Diff for /imach/src/imach.c between versions 1.4 and 1.120

version 1.4, 2001/05/02 17:34:41 version 1.120, 2006/03/16 15:10:38
Line 1 Line 1
      /* $Id$
 /*********************** Imach **************************************            $State$
   This program computes Healthy Life Expectancies from cross-longitudinal    $Log$
   data. Cross-longitudinal consist in a first survey ("cross") where    Revision 1.120  2006/03/16 15:10:38  lievre
   individuals from different ages are interviewed on their health status    (Module): refinements in the computation of lli if
   or degree of  disability. At least a second wave of interviews    status=-2 in order to have more reliable computation if stepm is
   ("longitudinal") should  measure each new individual health status.    not 1 month. Version 0.98f
   Health expectancies are computed from the transistions observed between  
   waves and are computed for each degree of severity of disability (number    Revision 1.119  2006/03/15 17:42:26  brouard
   of life states). More degrees you consider, more time is necessary to    (Module): Bug if status = -2, the loglikelihood was
   reach the Maximum Likelihood of the parameters involved in the model.    computed as likelihood omitting the logarithm. Version O.98e
   The simplest model is the multinomial logistic model where pij is  
   the probabibility to be observed in state j at the second wave conditional    Revision 1.118  2006/03/14 18:20:07  brouard
   to be observed in state i at the first wave. Therefore the model is:    (Module): varevsij Comments added explaining the second
   log(pij/pii)= aij + bij*age+ cij*sex + etc , where 'age' is age and 'sex'    table of variances if popbased=1 .
   is a covariate. If you want to have a more complex model than "constant and    (Module): Covariances of eij, ekl added, graphs fixed, new html link.
   age", you should modify the program where the markup    (Module): Function pstamp added
     *Covariates have to be included here again* invites you to do it.    (Module): Version 0.98d
   More covariates you add, less is the speed of the convergence.  
     Revision 1.117  2006/03/14 17:16:22  brouard
   The advantage that this computer programme claims, comes from that if the    (Module): varevsij Comments added explaining the second
   delay between waves is not identical for each individual, or if some    table of variances if popbased=1 .
   individual missed an interview, the information is not rounded or lost, but    (Module): Covariances of eij, ekl added, graphs fixed, new html link.
   taken into account using an interpolation or extrapolation.    (Module): Function pstamp added
   hPijx is the probability to be    (Module): Version 0.98d
   observed in state i at age x+h conditional to the observed state i at age  
   x. The delay 'h' can be split into an exact number (nh*stepm) of    Revision 1.116  2006/03/06 10:29:27  brouard
   unobserved intermediate  states. This elementary transition (by month or    (Module): Variance-covariance wrong links and
   quarter trimester, semester or year) is model as a multinomial logistic.    varian-covariance of ej. is needed (Saito).
   The hPx matrix is simply the matrix product of nh*stepm elementary matrices  
   and the contribution of each individual to the likelihood is simply hPijx.    Revision 1.115  2006/02/27 12:17:45  brouard
     (Module): One freematrix added in mlikeli! 0.98c
   Also this programme outputs the covariance matrix of the parameters but also  
   of the life expectancies. It also computes the prevalence limits.    Revision 1.114  2006/02/26 12:57:58  brouard
      (Module): Some improvements in processing parameter
   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).    filename with strsep.
            Institut national d'études démographiques, Paris.  
   This software have been partly granted by Euro-REVES, a concerted action    Revision 1.113  2006/02/24 14:20:24  brouard
   from the European Union.    (Module): Memory leaks checks with valgrind and:
   It is copyrighted identically to a GNU software product, ie programme and    datafile was not closed, some imatrix were not freed and on matrix
   software can be distributed freely for non commercial use. Latest version    allocation too.
   can be accessed at http://euroreves.ined.fr/imach .  
   **********************************************************************/    Revision 1.112  2006/01/30 09:55:26  brouard
      (Module): Back to gnuplot.exe instead of wgnuplot.exe
 #include <math.h>  
 #include <stdio.h>    Revision 1.111  2006/01/25 20:38:18  brouard
 #include <stdlib.h>    (Module): Lots of cleaning and bugs added (Gompertz)
 #include <unistd.h>    (Module): Comments can be added in data file. Missing date values
     can be a simple dot '.'.
 #define MAXLINE 256  
 #define FILENAMELENGTH 80    Revision 1.110  2006/01/25 00:51:50  brouard
 /*#define DEBUG*/    (Module): Lots of cleaning and bugs added (Gompertz)
 #define windows  
     Revision 1.109  2006/01/24 19:37:15  brouard
 #define MAXPARM 30 /* Maximum number of parameters for the optimization */    (Module): Comments (lines starting with a #) are allowed in data.
 #define NPARMAX 64 /* (nlstate+ndeath-1)*nlstate*ncovmodel */  
     Revision 1.108  2006/01/19 18:05:42  lievre
 #define NINTERVMAX 8    Gnuplot problem appeared...
 #define NLSTATEMAX 8 /* Maximum number of live states (for func) */    To be fixed
 #define NDEATHMAX 8 /* Maximum number of dead states (for func) */  
 #define NCOVMAX 8 /* Maximum number of covariates */    Revision 1.107  2006/01/19 16:20:37  brouard
 #define MAXN 20000    Test existence of gnuplot in imach path
 #define YEARM 12. /* Number of months per year */  
 #define AGESUP 130    Revision 1.106  2006/01/19 13:24:36  brouard
 #define AGEBASE 40    Some cleaning and links added in html output
   
     Revision 1.105  2006/01/05 20:23:19  lievre
 int nvar;    *** empty log message ***
 static int cptcov;  
 int cptcovn;    Revision 1.104  2005/09/30 16:11:43  lievre
 int npar=NPARMAX;    (Module): sump fixed, loop imx fixed, and simplifications.
 int nlstate=2; /* Number of live states */    (Module): If the status is missing at the last wave but we know
 int ndeath=1; /* Number of dead states */    that the person is alive, then we can code his/her status as -2
 int ncovmodel, ncov;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */    (instead of missing=-1 in earlier versions) and his/her
     contributions to the likelihood is 1 - Prob of dying from last
 int *wav; /* Number of waves for this individuual 0 is possible */    health status (= 1-p13= p11+p12 in the easiest case of somebody in
 int maxwav; /* Maxim number of waves */    the healthy state at last known wave). Version is 0.98
 int mle, weightopt;  
 int **mw; /* mw[mi][i] is number of the mi wave for this individual */    Revision 1.103  2005/09/30 15:54:49  lievre
 int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */    (Module): sump fixed, loop imx fixed, and simplifications.
 double **oldm, **newm, **savm; /* Working pointers to matrices */  
 double **oldms, **newms, **savms; /* Fixed working pointers to matrices */    Revision 1.102  2004/09/15 17:31:30  brouard
 FILE *fic,*ficpar, *ficparo,*ficres,  *ficrespl, *ficrespij, *ficrest;    Add the possibility to read data file including tab characters.
 FILE *ficgp, *fichtm;  
 FILE *ficreseij;    Revision 1.101  2004/09/15 10:38:38  brouard
   char filerese[FILENAMELENGTH];    Fix on curr_time
  FILE  *ficresvij;  
   char fileresv[FILENAMELENGTH];    Revision 1.100  2004/07/12 18:29:06  brouard
  FILE  *ficresvpl;    Add version for Mac OS X. Just define UNIX in Makefile
   char fileresvpl[FILENAMELENGTH];  
     Revision 1.99  2004/06/05 08:57:40  brouard
     *** empty log message ***
   
     Revision 1.98  2004/05/16 15:05:56  brouard
 #define NR_END 1    New version 0.97 . First attempt to estimate force of mortality
 #define FREE_ARG char*    directly from the data i.e. without the need of knowing the health
 #define FTOL 1.0e-10    state at each age, but using a Gompertz model: log u =a + b*age .
     This is the basic analysis of mortality and should be done before any
 #define NRANSI    other analysis, in order to test if the mortality estimated from the
 #define ITMAX 200    cross-longitudinal survey is different from the mortality estimated
     from other sources like vital statistic data.
 #define TOL 2.0e-4  
     The same imach parameter file can be used but the option for mle should be -3.
 #define CGOLD 0.3819660  
 #define ZEPS 1.0e-10    Agnès, who wrote this part of the code, tried to keep most of the
 #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d);    former routines in order to include the new code within the former code.
   
 #define GOLD 1.618034    The output is very simple: only an estimate of the intercept and of
 #define GLIMIT 100.0    the slope with 95% confident intervals.
 #define TINY 1.0e-20  
     Current limitations:
 static double maxarg1,maxarg2;    A) Even if you enter covariates, i.e. with the
 #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))    model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
 #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))    B) There is no computation of Life Expectancy nor Life Table.
    
 #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))    Revision 1.97  2004/02/20 13:25:42  lievre
 #define rint(a) floor(a+0.5)    Version 0.96d. Population forecasting command line is (temporarily)
     suppressed.
 static double sqrarg;  
 #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)    Revision 1.96  2003/07/15 15:38:55  brouard
 #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;}    * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
     rewritten within the same printf. Workaround: many printfs.
 int imx;  
 int stepm;    Revision 1.95  2003/07/08 07:54:34  brouard
 /* Stepm, step in month: minimum step interpolation*/    * imach.c (Repository):
     (Repository): Using imachwizard code to output a more meaningful covariance
 int m,nb;    matrix (cov(a12,c31) instead of numbers.
 int *num, firstpass=0, lastpass=4,*cod, *ncodemax;  
 double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;    Revision 1.94  2003/06/27 13:00:02  brouard
 double **pmmij;    Just cleaning
   
 double *weight;    Revision 1.93  2003/06/25 16:33:55  brouard
 int **s; /* Status */    (Module): On windows (cygwin) function asctime_r doesn't
 double *agedc, **covar, idx;    exist so I changed back to asctime which exists.
 int **nbcode, *Tcode, *Tvar, **codtab;    (Module): Version 0.96b
   
 double ftol=FTOL; /* Tolerance for computing Max Likelihood */    Revision 1.92  2003/06/25 16:30:45  brouard
 double ftolhess; /* Tolerance for computing hessian */    (Module): On windows (cygwin) function asctime_r doesn't
     exist so I changed back to asctime which exists.
   
 /******************************************/    Revision 1.91  2003/06/25 15:30:29  brouard
     * imach.c (Repository): Duplicated warning errors corrected.
 void replace(char *s, char*t)    (Repository): Elapsed time after each iteration is now output. It
 {    helps to forecast when convergence will be reached. Elapsed time
   int i;    is stamped in powell.  We created a new html file for the graphs
   int lg=20;    concerning matrix of covariance. It has extension -cov.htm.
   i=0;  
   lg=strlen(t);    Revision 1.90  2003/06/24 12:34:15  brouard
   for(i=0; i<= lg; i++) {    (Module): Some bugs corrected for windows. Also, when
     (s[i] = t[i]);    mle=-1 a template is output in file "or"mypar.txt with the design
     if (t[i]== '\\') s[i]='/';    of the covariance matrix to be input.
   }  
 }    Revision 1.89  2003/06/24 12:30:52  brouard
     (Module): Some bugs corrected for windows. Also, when
 int nbocc(char *s, char occ)    mle=-1 a template is output in file "or"mypar.txt with the design
 {    of the covariance matrix to be input.
   int i,j=0;  
   int lg=20;    Revision 1.88  2003/06/23 17:54:56  brouard
   i=0;    * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
   lg=strlen(s);  
   for(i=0; i<= lg; i++) {    Revision 1.87  2003/06/18 12:26:01  brouard
   if  (s[i] == occ ) j++;    Version 0.96
   }  
   return j;    Revision 1.86  2003/06/17 20:04:08  brouard
 }    (Module): Change position of html and gnuplot routines and added
     routine fileappend.
 void cutv(char *u,char *v, char*t, char occ)  
 {    Revision 1.85  2003/06/17 13:12:43  brouard
   int i,lg,j,p;    * imach.c (Repository): Check when date of death was earlier that
   i=0;    current date of interview. It may happen when the death was just
   for(j=0; j<=strlen(t)-1; j++) {    prior to the death. In this case, dh was negative and likelihood
     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1;    was wrong (infinity). We still send an "Error" but patch by
   }    assuming that the date of death was just one stepm after the
     interview.
   lg=strlen(t);    (Repository): Because some people have very long ID (first column)
   for(j=0; j<p; j++) {    we changed int to long in num[] and we added a new lvector for
     (u[j] = t[j]);    memory allocation. But we also truncated to 8 characters (left
     u[p]='\0';    truncation)
   }    (Repository): No more line truncation errors.
   
    for(j=0; j<= lg; j++) {    Revision 1.84  2003/06/13 21:44:43  brouard
     if (j>=(p+1))(v[j-p-1] = t[j]);    * imach.c (Repository): Replace "freqsummary" at a correct
   }    place. It differs from routine "prevalence" which may be called
 }    many times. Probs is memory consuming and must be used with
     parcimony.
 /********************** nrerror ********************/    Version 0.95a3 (should output exactly the same maximization than 0.8a2)
   
 void nrerror(char error_text[])    Revision 1.83  2003/06/10 13:39:11  lievre
 {    *** empty log message ***
   fprintf(stderr,"ERREUR ...\n");  
   fprintf(stderr,"%s\n",error_text);    Revision 1.82  2003/06/05 15:57:20  brouard
   exit(1);    Add log in  imach.c and  fullversion number is now printed.
 }  
 /*********************** vector *******************/  */
 double *vector(int nl, int nh)  /*
 {     Interpolated Markov Chain
   double *v;  
   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));    Short summary of the programme:
   if (!v) nrerror("allocation failure in vector");    
   return v-nl+NR_END;    This program computes Healthy Life Expectancies from
 }    cross-longitudinal data. Cross-longitudinal data consist in: -1- a
     first survey ("cross") where individuals from different ages are
 /************************ free vector ******************/    interviewed on their health status or degree of disability (in the
 void free_vector(double*v, int nl, int nh)    case of a health survey which is our main interest) -2- at least a
 {    second wave of interviews ("longitudinal") which measure each change
   free((FREE_ARG)(v+nl-NR_END));    (if any) in individual health status.  Health expectancies are
 }    computed from the time spent in each health state according to a
     model. More health states you consider, more time is necessary to reach the
 /************************ivector *******************************/    Maximum Likelihood of the parameters involved in the model.  The
 int *ivector(long nl,long nh)    simplest model is the multinomial logistic model where pij is the
 {    probability to be observed in state j at the second wave
   int *v;    conditional to be observed in state i at the first wave. Therefore
   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));    the model is: log(pij/pii)= aij + bij*age+ cij*sex + etc , where
   if (!v) nrerror("allocation failure in ivector");    'age' is age and 'sex' is a covariate. If you want to have a more
   return v-nl+NR_END;    complex model than "constant and age", you should modify the program
 }    where the markup *Covariates have to be included here again* invites
     you to do it.  More covariates you add, slower the
 /******************free ivector **************************/    convergence.
 void free_ivector(int *v, long nl, long nh)  
 {    The advantage of this computer programme, compared to a simple
   free((FREE_ARG)(v+nl-NR_END));    multinomial logistic model, is clear when the delay between waves is not
 }    identical for each individual. Also, if a individual missed an
     intermediate interview, the information is lost, but taken into
 /******************* imatrix *******************************/    account using an interpolation or extrapolation.  
 int **imatrix(long nrl, long nrh, long ncl, long nch)  
      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */    hPijx is the probability to be observed in state i at age x+h
 {    conditional to the observed state i at age x. The delay 'h' can be
   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1;    split into an exact number (nh*stepm) of unobserved intermediate
   int **m;    states. This elementary transition (by month, quarter,
      semester or year) is modelled as a multinomial logistic.  The hPx
   /* allocate pointers to rows */    matrix is simply the matrix product of nh*stepm elementary matrices
   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*)));    and the contribution of each individual to the likelihood is simply
   if (!m) nrerror("allocation failure 1 in matrix()");    hPijx.
   m += NR_END;  
   m -= nrl;    Also this programme outputs the covariance matrix of the parameters but also
      of the life expectancies. It also computes the period (stable) prevalence. 
      
   /* allocate rows and set pointers to them */    Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int)));             Institut national d'études démographiques, Paris.
   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");    This software have been partly granted by Euro-REVES, a concerted action
   m[nrl] += NR_END;    from the European Union.
   m[nrl] -= ncl;    It is copyrighted identically to a GNU software product, ie programme and
      software can be distributed freely for non commercial use. Latest version
   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol;    can be accessed at http://euroreves.ined.fr/imach .
    
   /* return pointer to array of pointers to rows */    Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
   return m;    or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
 }    
     **********************************************************************/
 /****************** free_imatrix *************************/  /*
 void free_imatrix(m,nrl,nrh,ncl,nch)    main
       int **m;    read parameterfile
       long nch,ncl,nrh,nrl;    read datafile
      /* free an int matrix allocated by imatrix() */    concatwav
 {    freqsummary
   free((FREE_ARG) (m[nrl]+ncl-NR_END));    if (mle >= 1)
   free((FREE_ARG) (m+nrl-NR_END));      mlikeli
 }    print results files
     if mle==1 
 /******************* matrix *******************************/       computes hessian
 double **matrix(long nrl, long nrh, long ncl, long nch)    read end of parameter file: agemin, agemax, bage, fage, estepm
 {        begin-prev-date,...
   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;    open gnuplot file
   double **m;    open html file
     period (stable) prevalence
   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));     for age prevalim()
   if (!m) nrerror("allocation failure 1 in matrix()");    h Pij x
   m += NR_END;    variance of p varprob
   m -= nrl;    forecasting if prevfcast==1 prevforecast call prevalence()
     health expectancies
   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));    Variance-covariance of DFLE
   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");    prevalence()
   m[nrl] += NR_END;     movingaverage()
   m[nrl] -= ncl;    varevsij() 
     if popbased==1 varevsij(,popbased)
   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;    total life expectancies
   return m;    Variance of period (stable) prevalence
 }   end
   */
 /*************************free matrix ************************/  
 void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)  
 {  
   free((FREE_ARG)(m[nrl]+ncl-NR_END));   
   free((FREE_ARG)(m+nrl-NR_END));  #include <math.h>
 }  #include <stdio.h>
   #include <stdlib.h>
 /******************* ma3x *******************************/  #include <string.h>
 double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)  #include <unistd.h>
 {  
   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;  #include <limits.h>
   double ***m;  #include <sys/types.h>
   #include <sys/stat.h>
   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));  #include <errno.h>
   if (!m) nrerror("allocation failure 1 in matrix()");  extern int errno;
   m += NR_END;  
   m -= nrl;  /* #include <sys/time.h> */
   #include <time.h>
   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));  #include "timeval.h"
   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");  
   m[nrl] += NR_END;  /* #include <libintl.h> */
   m[nrl] -= ncl;  /* #define _(String) gettext (String) */
   
   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;  #define MAXLINE 256
   
   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));  #define GNUPLOTPROGRAM "gnuplot"
   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");  /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
   m[nrl][ncl] += NR_END;  #define FILENAMELENGTH 132
   m[nrl][ncl] -= nll;  
   for (j=ncl+1; j<=nch; j++)  #define GLOCK_ERROR_NOPATH              -1      /* empty path */
     m[nrl][j]=m[nrl][j-1]+nlay;  #define GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
    
   for (i=nrl+1; i<=nrh; i++) {  #define MAXPARM 30 /* Maximum number of parameters for the optimization */
     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;  #define NPARMAX 64 /* (nlstate+ndeath-1)*nlstate*ncovmodel */
     for (j=ncl+1; j<=nch; j++)  
       m[i][j]=m[i][j-1]+nlay;  #define NINTERVMAX 8
   }  #define NLSTATEMAX 8 /* Maximum number of live states (for func) */
   return m;  #define NDEATHMAX 8 /* Maximum number of dead states (for func) */
 }  #define NCOVMAX 8 /* Maximum number of covariates */
   #define MAXN 20000
 /*************************free ma3x ************************/  #define YEARM 12. /* Number of months per year */
 void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)  #define AGESUP 130
 {  #define AGEBASE 40
   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));  #define AGEGOMP 10. /* Minimal age for Gompertz adjustment */
   free((FREE_ARG)(m[nrl]+ncl-NR_END));  #ifdef UNIX
   free((FREE_ARG)(m+nrl-NR_END));  #define DIRSEPARATOR '/'
 }  #define CHARSEPARATOR "/"
   #define ODIRSEPARATOR '\\'
 /***************** f1dim *************************/  #else
 extern int ncom;  #define DIRSEPARATOR '\\'
 extern double *pcom,*xicom;  #define CHARSEPARATOR "\\"
 extern double (*nrfunc)(double []);  #define ODIRSEPARATOR '/'
    #endif
 double f1dim(double x)  
 {  /* $Id$ */
   int j;  /* $State$ */
   double f;  
   double *xt;  char version[]="Imach version 0.98f, March 2006, INED-EUROREVES-Institut de longevite ";
    char fullversion[]="$Revision$ $Date$"; 
   xt=vector(1,ncom);  char strstart[80];
   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j];  char optionfilext[10], optionfilefiname[FILENAMELENGTH];
   f=(*nrfunc)(xt);  int erreur, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
   free_vector(xt,1,ncom);  int nvar;
   return f;  int cptcovn=0, cptcovage=0, cptcoveff=0,cptcov;
 }  int npar=NPARMAX;
   int nlstate=2; /* Number of live states */
 /*****************brent *************************/  int ndeath=1; /* Number of dead states */
 double brent(double ax, double bx, double cx, double (*f)(double), double tol,  double *xmin)  int ncovmodel, ncovcol;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
 {  int popbased=0;
   int iter;  
   double a,b,d,etemp;  int *wav; /* Number of waves for this individuual 0 is possible */
   double fu,fv,fw,fx;  int maxwav; /* Maxim number of waves */
   double ftemp;  int jmin, jmax; /* min, max spacing between 2 waves */
   double p,q,r,tol1,tol2,u,v,w,x,xm;  int ijmin, ijmax; /* Individuals having jmin and jmax */ 
   double e=0.0;  int gipmx, gsw; /* Global variables on the number of contributions 
                       to the likelihood and the sum of weights (done by funcone)*/
   a=(ax < cx ? ax : cx);  int mle, weightopt;
   b=(ax > cx ? ax : cx);  int **mw; /* mw[mi][i] is number of the mi wave for this individual */
   x=w=v=bx;  int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
   fw=fv=fx=(*f)(x);  int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
   for (iter=1;iter<=ITMAX;iter++) {             * wave mi and wave mi+1 is not an exact multiple of stepm. */
     xm=0.5*(a+b);  double jmean; /* Mean space between 2 waves */
     tol2=2.0*(tol1=tol*fabs(x)+ZEPS);  double **oldm, **newm, **savm; /* Working pointers to matrices */
     /*          if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/  double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
     printf(".");fflush(stdout);  FILE *fic,*ficpar, *ficparo,*ficres, *ficresp, *ficrespl, *ficrespij, *ficrest,*ficresf,*ficrespop;
 #ifdef DEBUG  FILE *ficlog, *ficrespow;
     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);  int globpr; /* Global variable for printing or not */
     /*          if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */  double fretone; /* Only one call to likelihood */
 #endif  long ipmx; /* Number of contributions */
     if (fabs(x-xm) <= (tol2-0.5*(b-a))){  double sw; /* Sum of weights */
       *xmin=x;  char filerespow[FILENAMELENGTH];
       return fx;  char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
     }  FILE *ficresilk;
     ftemp=fu;  FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
     if (fabs(e) > tol1) {  FILE *ficresprobmorprev;
       r=(x-w)*(fx-fv);  FILE *fichtm, *fichtmcov; /* Html File */
       q=(x-v)*(fx-fw);  FILE *ficreseij;
       p=(x-v)*q-(x-w)*r;  char filerese[FILENAMELENGTH];
       q=2.0*(q-r);  FILE *ficresstdeij;
       if (q > 0.0) p = -p;  char fileresstde[FILENAMELENGTH];
       q=fabs(q);  FILE *ficrescveij;
       etemp=e;  char filerescve[FILENAMELENGTH];
       e=d;  FILE  *ficresvij;
       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x))  char fileresv[FILENAMELENGTH];
         d=CGOLD*(e=(x >= xm ? a-x : b-x));  FILE  *ficresvpl;
       else {  char fileresvpl[FILENAMELENGTH];
         d=p/q;  char title[MAXLINE];
         u=x+d;  char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH];
         if (u-a < tol2 || b-u < tol2)  char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
           d=SIGN(tol1,xm-x);  char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
       }  char command[FILENAMELENGTH];
     } else {  int  outcmd=0;
       d=CGOLD*(e=(x >= xm ? a-x : b-x));  
     }  char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d));  
     fu=(*f)(u);  char filelog[FILENAMELENGTH]; /* Log file */
     if (fu <= fx) {  char filerest[FILENAMELENGTH];
       if (u >= x) a=x; else b=x;  char fileregp[FILENAMELENGTH];
       SHFT(v,w,x,u)  char popfile[FILENAMELENGTH];
         SHFT(fv,fw,fx,fu)  
         } else {  char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
           if (u < x) a=u; else b=u;  
           if (fu <= fw || w == x) {  struct timeval start_time, end_time, curr_time, last_time, forecast_time;
             v=w;  struct timezone tzp;
             w=u;  extern int gettimeofday();
             fv=fw;  struct tm tmg, tm, tmf, *gmtime(), *localtime();
             fw=fu;  long time_value;
           } else if (fu <= fv || v == x || v == w) {  extern long time();
             v=u;  char strcurr[80], strfor[80];
             fv=fu;  
           }  char *endptr;
         }  long lval;
   }  
   nrerror("Too many iterations in brent");  #define NR_END 1
   *xmin=x;  #define FREE_ARG char*
   return fx;  #define FTOL 1.0e-10
 }  
   #define NRANSI 
 /****************** mnbrak ***********************/  #define ITMAX 200 
   
 void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc,  #define TOL 2.0e-4 
             double (*func)(double))  
 {  #define CGOLD 0.3819660 
   double ulim,u,r,q, dum;  #define ZEPS 1.0e-10 
   double fu;  #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
    
   *fa=(*func)(*ax);  #define GOLD 1.618034 
   *fb=(*func)(*bx);  #define GLIMIT 100.0 
   if (*fb > *fa) {  #define TINY 1.0e-20 
     SHFT(dum,*ax,*bx,dum)  
       SHFT(dum,*fb,*fa,dum)  static double maxarg1,maxarg2;
       }  #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
   *cx=(*bx)+GOLD*(*bx-*ax);  #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
   *fc=(*func)(*cx);    
   while (*fb > *fc) {  #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
     r=(*bx-*ax)*(*fb-*fc);  #define rint(a) floor(a+0.5)
     q=(*bx-*cx)*(*fb-*fa);  
     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/  static double sqrarg;
       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r));  #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
     ulim=(*bx)+GLIMIT*(*cx-*bx);  #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
     if ((*bx-u)*(u-*cx) > 0.0) {  int agegomp= AGEGOMP;
       fu=(*func)(u);  
     } else if ((*cx-u)*(u-ulim) > 0.0) {  int imx; 
       fu=(*func)(u);  int stepm=1;
       if (fu < *fc) {  /* Stepm, step in month: minimum step interpolation*/
         SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx))  
           SHFT(*fb,*fc,fu,(*func)(u))  int estepm;
           }  /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
     } else if ((u-ulim)*(ulim-*cx) >= 0.0) {  
       u=ulim;  int m,nb;
       fu=(*func)(u);  long *num;
     } else {  int firstpass=0, lastpass=4,*cod, *ncodemax, *Tage,*cens;
       u=(*cx)+GOLD*(*cx-*bx);  double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
       fu=(*func)(u);  double **pmmij, ***probs;
     }  double *ageexmed,*agecens;
     SHFT(*ax,*bx,*cx,u)  double dateintmean=0;
       SHFT(*fa,*fb,*fc,fu)  
       }  double *weight;
 }  int **s; /* Status */
   double *agedc, **covar, idx;
 /*************** linmin ************************/  int **nbcode, *Tcode, *Tvar, **codtab, **Tvard, *Tprod, cptcovprod, *Tvaraff;
   double *lsurv, *lpop, *tpop;
 int ncom;  
 double *pcom,*xicom;  double ftol=FTOL; /* Tolerance for computing Max Likelihood */
 double (*nrfunc)(double []);  double ftolhess; /* Tolerance for computing hessian */
    
 void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []))  /**************** split *************************/
 {  static  int split( char *path, char *dirc, char *name, char *ext, char *finame )
   double brent(double ax, double bx, double cx,  {
                double (*f)(double), double tol, double *xmin);    /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
   double f1dim(double x);       the name of the file (name), its extension only (ext) and its first part of the name (finame)
   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb,    */ 
               double *fc, double (*func)(double));    char  *ss;                            /* pointer */
   int j;    int   l1, l2;                         /* length counters */
   double xx,xmin,bx,ax;  
   double fx,fb,fa;    l1 = strlen(path );                   /* length of path */
      if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
   ncom=n;    ss= strrchr( path, DIRSEPARATOR );            /* find last / */
   pcom=vector(1,n);    if ( ss == NULL ) {                   /* no directory, so determine current directory */
   xicom=vector(1,n);      strcpy( name, path );               /* we got the fullname name because no directory */
   nrfunc=func;      /*if(strrchr(path, ODIRSEPARATOR )==NULL)
   for (j=1;j<=n;j++) {        printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
     pcom[j]=p[j];      /* get current working directory */
     xicom[j]=xi[j];      /*    extern  char* getcwd ( char *buf , int len);*/
   }      if ( getcwd( dirc, FILENAME_MAX ) == NULL ) {
   ax=0.0;        return( GLOCK_ERROR_GETCWD );
   xx=1.0;      }
   mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);      /* got dirc from getcwd*/
   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin);      printf(" DIRC = %s \n",dirc);
 #ifdef DEBUG    } else {                              /* strip direcotry from path */
   printf("retour brent fret=%.12e xmin=%.12e\n",*fret,xmin);      ss++;                               /* after this, the filename */
 #endif      l2 = strlen( ss );                  /* length of filename */
   for (j=1;j<=n;j++) {      if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
     xi[j] *= xmin;      strcpy( name, ss );         /* save file name */
     p[j] += xi[j];      strncpy( dirc, path, l1 - l2 );     /* now the directory */
   }      dirc[l1-l2] = 0;                    /* add zero */
   free_vector(xicom,1,n);      printf(" DIRC2 = %s \n",dirc);
   free_vector(pcom,1,n);    }
 }    /* We add a separator at the end of dirc if not exists */
     l1 = strlen( dirc );                  /* length of directory */
 /*************** powell ************************/    if( dirc[l1-1] != DIRSEPARATOR ){
 void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret,      dirc[l1] =  DIRSEPARATOR;
             double (*func)(double []))      dirc[l1+1] = 0; 
 {      printf(" DIRC3 = %s \n",dirc);
   void linmin(double p[], double xi[], int n, double *fret,    }
               double (*func)(double []));    ss = strrchr( name, '.' );            /* find last / */
   int i,ibig,j;    if (ss >0){
   double del,t,*pt,*ptt,*xit;      ss++;
   double fp,fptt;      strcpy(ext,ss);                     /* save extension */
   double *xits;      l1= strlen( name);
   pt=vector(1,n);      l2= strlen(ss)+1;
   ptt=vector(1,n);      strncpy( finame, name, l1-l2);
   xit=vector(1,n);      finame[l1-l2]= 0;
   xits=vector(1,n);    }
   *fret=(*func)(p);  
   for (j=1;j<=n;j++) pt[j]=p[j];    return( 0 );                          /* we're done */
   for (*iter=1;;++(*iter)) {  }
     fp=(*fret);  
     ibig=0;  
     del=0.0;  /******************************************/
     printf("\nPowell iter=%d -2*LL=%.12f",*iter,*fret);  
     for (i=1;i<=n;i++)  void replace_back_to_slash(char *s, char*t)
       printf(" %d %.12f",i, p[i]);  {
     printf("\n");    int i;
     for (i=1;i<=n;i++) {    int lg=0;
       for (j=1;j<=n;j++) xit[j]=xi[j][i];    i=0;
       fptt=(*fret);    lg=strlen(t);
 #ifdef DEBUG    for(i=0; i<= lg; i++) {
       printf("fret=%lf \n",*fret);      (s[i] = t[i]);
 #endif      if (t[i]== '\\') s[i]='/';
       printf("%d",i);fflush(stdout);    }
       linmin(p,xit,n,fret,func);  }
       if (fabs(fptt-(*fret)) > del) {  
         del=fabs(fptt-(*fret));  int nbocc(char *s, char occ)
         ibig=i;  {
       }    int i,j=0;
 #ifdef DEBUG    int lg=20;
       printf("%d %.12e",i,(*fret));    i=0;
       for (j=1;j<=n;j++) {    lg=strlen(s);
         xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);    for(i=0; i<= lg; i++) {
         printf(" x(%d)=%.12e",j,xit[j]);    if  (s[i] == occ ) j++;
       }    }
       for(j=1;j<=n;j++)    return j;
         printf(" p=%.12e",p[j]);  }
       printf("\n");  
 #endif  void cutv(char *u,char *v, char*t, char occ)
     }  {
     if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) {    /* cuts string t into u and v where u ends before first occurence of char 'occ' 
 #ifdef DEBUG       and v starts after first occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2')
       int k[2],l;       gives u="abcedf" and v="ghi2j" */
       k[0]=1;    int i,lg,j,p=0;
       k[1]=-1;    i=0;
       printf("Max: %.12e",(*func)(p));    for(j=0; j<=strlen(t)-1; j++) {
       for (j=1;j<=n;j++)      if((t[j]!= occ) && (t[j+1]== occ)) p=j+1;
         printf(" %.12e",p[j]);    }
       printf("\n");  
       for(l=0;l<=1;l++) {    lg=strlen(t);
         for (j=1;j<=n;j++) {    for(j=0; j<p; j++) {
           ptt[j]=p[j]+(p[j]-pt[j])*k[l];      (u[j] = t[j]);
           printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);    }
         }       u[p]='\0';
         printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));  
       }     for(j=0; j<= lg; j++) {
 #endif      if (j>=(p+1))(v[j-p-1] = t[j]);
     }
   }
       free_vector(xit,1,n);  
       free_vector(xits,1,n);  /********************** nrerror ********************/
       free_vector(ptt,1,n);  
       free_vector(pt,1,n);  void nrerror(char error_text[])
       return;  {
     }    fprintf(stderr,"ERREUR ...\n");
     if (*iter == ITMAX) nrerror("powell exceeding maximum iterations.");    fprintf(stderr,"%s\n",error_text);
     for (j=1;j<=n;j++) {    exit(EXIT_FAILURE);
       ptt[j]=2.0*p[j]-pt[j];  }
       xit[j]=p[j]-pt[j];  /*********************** vector *******************/
       pt[j]=p[j];  double *vector(int nl, int nh)
     }  {
     fptt=(*func)(ptt);    double *v;
     if (fptt < fp) {    v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt);    if (!v) nrerror("allocation failure in vector");
       if (t < 0.0) {    return v-nl+NR_END;
         linmin(p,xit,n,fret,func);  }
         for (j=1;j<=n;j++) {  
           xi[j][ibig]=xi[j][n];  /************************ free vector ******************/
           xi[j][n]=xit[j];  void free_vector(double*v, int nl, int nh)
         }  {
 #ifdef DEBUG    free((FREE_ARG)(v+nl-NR_END));
         printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);  }
         for(j=1;j<=n;j++)  
           printf(" %.12e",xit[j]);  /************************ivector *******************************/
         printf("\n");  int *ivector(long nl,long nh)
 #endif  {
       }    int *v;
     }    v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
   }    if (!v) nrerror("allocation failure in ivector");
 }    return v-nl+NR_END;
   }
 /**** Prevalence limit ****************/  
   /******************free ivector **************************/
 double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int ij)  void free_ivector(int *v, long nl, long nh)
 {  {
   /* Computes the prevalence limit in each live state at age x by left multiplying the unit    free((FREE_ARG)(v+nl-NR_END));
      matrix by transitions matrix until convergence is reached */  }
   
   int i, ii,j,k;  /************************lvector *******************************/
   double min, max, maxmin, maxmax,sumnew=0.;  long *lvector(long nl,long nh)
   double **matprod2();  {
   double **out, cov[NCOVMAX], **pmij();    long *v;
   double **newm;    v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
   double agefin, delaymax=50 ; /* Max number of years to converge */    if (!v) nrerror("allocation failure in ivector");
     return v-nl+NR_END;
   for (ii=1;ii<=nlstate+ndeath;ii++)  }
     for (j=1;j<=nlstate+ndeath;j++){  
       oldm[ii][j]=(ii==j ? 1.0 : 0.0);  /******************free lvector **************************/
     }  void free_lvector(long *v, long nl, long nh)
   /* Even if hstepm = 1, at least one multiplication by the unit matrix */  {
   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){    free((FREE_ARG)(v+nl-NR_END));
     newm=savm;  }
     /* Covariates have to be included here again */  
     cov[1]=1.;  /******************* imatrix *******************************/
     cov[2]=agefin;  int **imatrix(long nrl, long nrh, long ncl, long nch) 
     if (cptcovn>0){       /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
       for (k=1; k<=cptcovn;k++) {cov[2+k]=nbcode[Tvar[k]][codtab[ij][k]];/*printf("Tcode[ij]=%d nbcode=%d\n",Tcode[ij],nbcode[k][Tcode[ij]]);*/}  { 
     }    long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);    int **m; 
     
     savm=oldm;    /* allocate pointers to rows */ 
     oldm=newm;    m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
     maxmax=0.;    if (!m) nrerror("allocation failure 1 in matrix()"); 
     for(j=1;j<=nlstate;j++){    m += NR_END; 
       min=1.;    m -= nrl; 
       max=0.;    
       for(i=1; i<=nlstate; i++) {    
         sumnew=0;    /* allocate rows and set pointers to them */ 
         for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];    m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
         prlim[i][j]= newm[i][j]/(1-sumnew);    if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
         max=FMAX(max,prlim[i][j]);    m[nrl] += NR_END; 
         min=FMIN(min,prlim[i][j]);    m[nrl] -= ncl; 
       }    
       maxmin=max-min;    for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
       maxmax=FMAX(maxmax,maxmin);    
     }    /* return pointer to array of pointers to rows */ 
     if(maxmax < ftolpl){    return m; 
       return prlim;  } 
     }  
   }  /****************** free_imatrix *************************/
 }  void free_imatrix(m,nrl,nrh,ncl,nch)
         int **m;
 /*************** transition probabilities **********/        long nch,ncl,nrh,nrl; 
        /* free an int matrix allocated by imatrix() */ 
 double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )  { 
 {    free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
   double s1, s2;    free((FREE_ARG) (m+nrl-NR_END)); 
   /*double t34;*/  } 
   int i,j,j1, nc, ii, jj;  
   /******************* matrix *******************************/
     for(i=1; i<= nlstate; i++){  double **matrix(long nrl, long nrh, long ncl, long nch)
     for(j=1; j<i;j++){  {
       for (nc=1, s2=0.;nc <=ncovmodel; nc++){    long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
         /*s2 += param[i][j][nc]*cov[nc];*/    double **m;
         s2 += x[(i-1)*nlstate*ncovmodel+(j-1)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];  
         /*printf("Int j<i s1=%.17e, s2=%.17e\n",s1,s2);*/    m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
       }    if (!m) nrerror("allocation failure 1 in matrix()");
       ps[i][j]=s2;    m += NR_END;
       /*printf("s1=%.17e, s2=%.17e\n",s1,s2);*/    m -= nrl;
     }  
     for(j=i+1; j<=nlstate+ndeath;j++){    m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
       for (nc=1, s2=0.;nc <=ncovmodel; nc++){    if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
         s2 += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];    m[nrl] += NR_END;
         /*printf("Int j>i s1=%.17e, s2=%.17e %lx %lx\n",s1,s2,s1,s2);*/    m[nrl] -= ncl;
       }  
       ps[i][j]=s2;    for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
     }    return m;
   }    /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) 
   for(i=1; i<= nlstate; i++){     */
      s1=0;  }
     for(j=1; j<i; j++)  
       s1+=exp(ps[i][j]);  /*************************free matrix ************************/
     for(j=i+1; j<=nlstate+ndeath; j++)  void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
       s1+=exp(ps[i][j]);  {
     ps[i][i]=1./(s1+1.);    free((FREE_ARG)(m[nrl]+ncl-NR_END));
     for(j=1; j<i; j++)    free((FREE_ARG)(m+nrl-NR_END));
       ps[i][j]= exp(ps[i][j])*ps[i][i];  }
     for(j=i+1; j<=nlstate+ndeath; j++)  
       ps[i][j]= exp(ps[i][j])*ps[i][i];  /******************* ma3x *******************************/
     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */  double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
   } /* end i */  {
     long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){    double ***m;
     for(jj=1; jj<= nlstate+ndeath; jj++){  
       ps[ii][jj]=0;    m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
       ps[ii][ii]=1;    if (!m) nrerror("allocation failure 1 in matrix()");
     }    m += NR_END;
   }    m -= nrl;
   
   /*   for(ii=1; ii<= nlstate+ndeath; ii++){    m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
     for(jj=1; jj<= nlstate+ndeath; jj++){    if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
      printf("%lf ",ps[ii][jj]);    m[nrl] += NR_END;
    }    m[nrl] -= ncl;
     printf("\n ");  
     }    for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
     printf("\n ");printf("%lf ",cov[2]);*/  
 /*    m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
   for(i=1; i<= npar; i++) printf("%f ",x[i]);    if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
   goto end;*/    m[nrl][ncl] += NR_END;
     return ps;    m[nrl][ncl] -= nll;
 }    for (j=ncl+1; j<=nch; j++) 
       m[nrl][j]=m[nrl][j-1]+nlay;
 /**************** Product of 2 matrices ******************/    
     for (i=nrl+1; i<=nrh; i++) {
 double **matprod2(double **out, double **in,long nrl, long nrh, long ncl, long nch, long ncolol, long ncoloh, double **b)      m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
 {      for (j=ncl+1; j<=nch; j++) 
   /* Computes the matric product of in(1,nrh-nrl+1)(1,nch-ncl+1) times        m[i][j]=m[i][j-1]+nlay;
      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */    }
   /* in, b, out are matrice of pointers which should have been initialized    return m; 
      before: only the contents of out is modified. The function returns    /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
      a pointer to pointers identical to out */             &(m[i][j][k]) <=> *((*(m+i) + j)+k)
   long i, j, k;    */
   for(i=nrl; i<= nrh; i++)  }
     for(k=ncolol; k<=ncoloh; k++)  
       for(j=ncl,out[i][k]=0.; j<=nch; j++)  /*************************free ma3x ************************/
         out[i][k] +=in[i][j]*b[j][k];  void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
   {
   return out;    free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
 }    free((FREE_ARG)(m[nrl]+ncl-NR_END));
     free((FREE_ARG)(m+nrl-NR_END));
   }
 /************* Higher Matrix Product ***************/  
   /*************** function subdirf ***********/
 double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij )  char *subdirf(char fileres[])
 {  {
   /* Computes the transition matrix starting at age 'age' over 'nhstepm*hstepm*stepm' month    /* Caution optionfilefiname is hidden */
      duration (i.e. until    strcpy(tmpout,optionfilefiname);
      age (in years)  age+nhstepm*stepm/12) by multiplying nhstepm*hstepm matrices.    strcat(tmpout,"/"); /* Add to the right */
      Output is stored in matrix po[i][j][h] for h every 'hstepm' step    strcat(tmpout,fileres);
      (typically every 2 years instead of every month which is too big).    return tmpout;
      Model is determined by parameters x and covariates have to be  }
      included manually here.  
   /*************** function subdirf2 ***********/
      */  char *subdirf2(char fileres[], char *preop)
   {
   int i, j, d, h, k;    
   double **out, cov[NCOVMAX];    /* Caution optionfilefiname is hidden */
   double **newm;    strcpy(tmpout,optionfilefiname);
     strcat(tmpout,"/");
   /* Hstepm could be zero and should return the unit matrix */    strcat(tmpout,preop);
   for (i=1;i<=nlstate+ndeath;i++)    strcat(tmpout,fileres);
     for (j=1;j<=nlstate+ndeath;j++){    return tmpout;
       oldm[i][j]=(i==j ? 1.0 : 0.0);  }
       po[i][j][0]=(i==j ? 1.0 : 0.0);  
     }  /*************** function subdirf3 ***********/
   /* Even if hstepm = 1, at least one multiplication by the unit matrix */  char *subdirf3(char fileres[], char *preop, char *preop2)
   for(h=1; h <=nhstepm; h++){  {
     for(d=1; d <=hstepm; d++){    
       newm=savm;    /* Caution optionfilefiname is hidden */
       /* Covariates have to be included here again */    strcpy(tmpout,optionfilefiname);
       cov[1]=1.;    strcat(tmpout,"/");
       cov[2]=age+((h-1)*hstepm + (d-1))*stepm/YEARM;    strcat(tmpout,preop);
       if (cptcovn>0){    strcat(tmpout,preop2);
       for (k=1; k<=cptcovn;k++) cov[2+k]=nbcode[Tvar[k]][codtab[ij][k]];    strcat(tmpout,fileres);
     }    return tmpout;
       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/  }
       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/  
       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,  /***************** f1dim *************************/
                    pmij(pmmij,cov,ncovmodel,x,nlstate));  extern int ncom; 
       savm=oldm;  extern double *pcom,*xicom;
       oldm=newm;  extern double (*nrfunc)(double []); 
     }   
     for(i=1; i<=nlstate+ndeath; i++)  double f1dim(double x) 
       for(j=1;j<=nlstate+ndeath;j++) {  { 
         po[i][j][h]=newm[i][j];    int j; 
         /*printf("i=%d j=%d h=%d po[i][j][h]=%f ",i,j,h,po[i][j][h]);    double f;
          */    double *xt; 
       }   
   } /* end h */    xt=vector(1,ncom); 
   return po;    for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
 }    f=(*nrfunc)(xt); 
     free_vector(xt,1,ncom); 
     return f; 
 /*************** log-likelihood *************/  } 
 double func( double *x)  
 {  /*****************brent *************************/
   int i, ii, j, k, mi, d;  double brent(double ax, double bx, double cx, double (*f)(double), double tol,  double *xmin) 
   double l, ll[NLSTATEMAX], cov[NCOVMAX];  { 
   double **out;    int iter; 
   double sw; /* Sum of weights */    double a,b,d,etemp;
   double lli; /* Individual log likelihood */    double fu,fv,fw,fx;
   long ipmx;    double ftemp;
   /*extern weight */    double p,q,r,tol1,tol2,u,v,w,x,xm; 
   /* We are differentiating ll according to initial status */    double e=0.0; 
   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/   
   /*for(i=1;i<imx;i++)    a=(ax < cx ? ax : cx); 
 printf(" %d\n",s[4][i]);    b=(ax > cx ? ax : cx); 
   */    x=w=v=bx; 
     fw=fv=fx=(*f)(x); 
   for(k=1; k<=nlstate; k++) ll[k]=0.;    for (iter=1;iter<=ITMAX;iter++) { 
   for (i=1,ipmx=0, sw=0.; i<=imx; i++){      xm=0.5*(a+b); 
        for(mi=1; mi<= wav[i]-1; mi++){      tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
       for (ii=1;ii<=nlstate+ndeath;ii++)      /*          if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
         for (j=1;j<=nlstate+ndeath;j++) oldm[ii][j]=(ii==j ? 1.0 : 0.0);      printf(".");fflush(stdout);
             for(d=0; d<dh[mi][i]; d++){      fprintf(ficlog,".");fflush(ficlog);
         newm=savm;  #ifdef DEBUG
           cov[1]=1.;      printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
           cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;      fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
           if (cptcovn>0){      /*          if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
             for (k=1; k<=cptcovn;k++) cov[2+k]=covar[1+k-1][i];  #endif
             }      if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
           out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,        *xmin=x; 
                        1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));        return fx; 
           savm=oldm;      } 
           oldm=newm;      ftemp=fu;
       if (fabs(e) > tol1) { 
         r=(x-w)*(fx-fv); 
       } /* end mult */        q=(x-v)*(fx-fw); 
            p=(x-v)*q-(x-w)*r; 
       lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);        q=2.0*(q-r); 
       /* printf(" %f ",out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/        if (q > 0.0) p = -p; 
       ipmx +=1;        q=fabs(q); 
       sw += weight[i];        etemp=e; 
       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;        e=d; 
     } /* end of wave */        if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
   } /* end of individual */          d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
         else { 
   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];          d=p/q; 
   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */          u=x+d; 
   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */          if (u-a < tol2 || b-u < tol2) 
   return -l;            d=SIGN(tol1,xm-x); 
 }        } 
       } else { 
         d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
 /*********** Maximum Likelihood Estimation ***************/      } 
       u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
 void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))      fu=(*f)(u); 
 {      if (fu <= fx) { 
   int i,j, iter;        if (u >= x) a=x; else b=x; 
   double **xi,*delti;        SHFT(v,w,x,u) 
   double fret;          SHFT(fv,fw,fx,fu) 
   xi=matrix(1,npar,1,npar);          } else { 
   for (i=1;i<=npar;i++)            if (u < x) a=u; else b=u; 
     for (j=1;j<=npar;j++)            if (fu <= fw || w == x) { 
       xi[i][j]=(i==j ? 1.0 : 0.0);              v=w; 
   printf("Powell\n");              w=u; 
   powell(p,xi,npar,ftol,&iter,&fret,func);              fv=fw; 
               fw=fu; 
    printf("\n#Number of iterations = %d, -2 Log likelihood = %.12f\n",iter,func(p));            } else if (fu <= fv || v == x || v == w) { 
   fprintf(ficres,"#Number of iterations = %d, -2 Log likelihood = %.12f ",iter,func(p));              v=u; 
               fv=fu; 
 }            } 
           } 
 /**** Computes Hessian and covariance matrix ***/    } 
 void hesscov(double **matcov, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))    nrerror("Too many iterations in brent"); 
 {    *xmin=x; 
   double  **a,**y,*x,pd;    return fx; 
   double **hess;  } 
   int i, j,jk;  
   int *indx;  /****************** mnbrak ***********************/
   
   double hessii(double p[], double delta, int theta, double delti[]);  void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
   double hessij(double p[], double delti[], int i, int j);              double (*func)(double)) 
   void lubksb(double **a, int npar, int *indx, double b[]) ;  { 
   void ludcmp(double **a, int npar, int *indx, double *d) ;    double ulim,u,r,q, dum;
     double fu; 
    
   hess=matrix(1,npar,1,npar);    *fa=(*func)(*ax); 
     *fb=(*func)(*bx); 
   printf("\nCalculation of the hessian matrix. Wait...\n");    if (*fb > *fa) { 
   for (i=1;i<=npar;i++){      SHFT(dum,*ax,*bx,dum) 
     printf("%d",i);fflush(stdout);        SHFT(dum,*fb,*fa,dum) 
     hess[i][i]=hessii(p,ftolhess,i,delti);        } 
     /*printf(" %f ",p[i]);*/    *cx=(*bx)+GOLD*(*bx-*ax); 
   }    *fc=(*func)(*cx); 
     while (*fb > *fc) { 
   for (i=1;i<=npar;i++) {      r=(*bx-*ax)*(*fb-*fc); 
     for (j=1;j<=npar;j++)  {      q=(*bx-*cx)*(*fb-*fa); 
       if (j>i) {      u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
         printf(".%d%d",i,j);fflush(stdout);        (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); 
         hess[i][j]=hessij(p,delti,i,j);      ulim=(*bx)+GLIMIT*(*cx-*bx); 
         hess[j][i]=hess[i][j];      if ((*bx-u)*(u-*cx) > 0.0) { 
       }        fu=(*func)(u); 
     }      } else if ((*cx-u)*(u-ulim) > 0.0) { 
   }        fu=(*func)(u); 
   printf("\n");        if (fu < *fc) { 
           SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");            SHFT(*fb,*fc,fu,(*func)(u)) 
              } 
   a=matrix(1,npar,1,npar);      } else if ((u-ulim)*(ulim-*cx) >= 0.0) { 
   y=matrix(1,npar,1,npar);        u=ulim; 
   x=vector(1,npar);        fu=(*func)(u); 
   indx=ivector(1,npar);      } else { 
   for (i=1;i<=npar;i++)        u=(*cx)+GOLD*(*cx-*bx); 
     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];        fu=(*func)(u); 
   ludcmp(a,npar,indx,&pd);      } 
       SHFT(*ax,*bx,*cx,u) 
   for (j=1;j<=npar;j++) {        SHFT(*fa,*fb,*fc,fu) 
     for (i=1;i<=npar;i++) x[i]=0;        } 
     x[j]=1;  } 
     lubksb(a,npar,indx,x);  
     for (i=1;i<=npar;i++){  /*************** linmin ************************/
       matcov[i][j]=x[i];  
     }  int ncom; 
   }  double *pcom,*xicom;
   double (*nrfunc)(double []); 
   printf("\n#Hessian matrix#\n");   
   for (i=1;i<=npar;i++) {  void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
     for (j=1;j<=npar;j++) {  { 
       printf("%.3e ",hess[i][j]);    double brent(double ax, double bx, double cx, 
     }                 double (*f)(double), double tol, double *xmin); 
     printf("\n");    double f1dim(double x); 
   }    void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                 double *fc, double (*func)(double)); 
   /* Recompute Inverse */    int j; 
   for (i=1;i<=npar;i++)    double xx,xmin,bx,ax; 
     for (j=1;j<=npar;j++) a[i][j]=matcov[i][j];    double fx,fb,fa;
   ludcmp(a,npar,indx,&pd);   
     ncom=n; 
   /*  printf("\n#Hessian matrix recomputed#\n");    pcom=vector(1,n); 
     xicom=vector(1,n); 
   for (j=1;j<=npar;j++) {    nrfunc=func; 
     for (i=1;i<=npar;i++) x[i]=0;    for (j=1;j<=n;j++) { 
     x[j]=1;      pcom[j]=p[j]; 
     lubksb(a,npar,indx,x);      xicom[j]=xi[j]; 
     for (i=1;i<=npar;i++){    } 
       y[i][j]=x[i];    ax=0.0; 
       printf("%.3e ",y[i][j]);    xx=1.0; 
     }    mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim); 
     printf("\n");    *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); 
   }  #ifdef DEBUG
   */    printf("retour brent fret=%.12e xmin=%.12e\n",*fret,xmin);
     fprintf(ficlog,"retour brent fret=%.12e xmin=%.12e\n",*fret,xmin);
   free_matrix(a,1,npar,1,npar);  #endif
   free_matrix(y,1,npar,1,npar);    for (j=1;j<=n;j++) { 
   free_vector(x,1,npar);      xi[j] *= xmin; 
   free_ivector(indx,1,npar);      p[j] += xi[j]; 
   free_matrix(hess,1,npar,1,npar);    } 
     free_vector(xicom,1,n); 
     free_vector(pcom,1,n); 
 }  } 
   
 /*************** hessian matrix ****************/  char *asc_diff_time(long time_sec, char ascdiff[])
 double hessii( double x[], double delta, int theta, double delti[])  {
 {    long sec_left, days, hours, minutes;
   int i;    days = (time_sec) / (60*60*24);
   int l=1, lmax=20;    sec_left = (time_sec) % (60*60*24);
   double k1,k2;    hours = (sec_left) / (60*60) ;
   double p2[NPARMAX+1];    sec_left = (sec_left) %(60*60);
   double res;    minutes = (sec_left) /60;
   double delt, delts, nkhi=10.,nkhif=1., khi=1.e-4;    sec_left = (sec_left) % (60);
   double fx;    sprintf(ascdiff,"%d day(s) %d hour(s) %d minute(s) %d second(s)",days, hours, minutes, sec_left);  
   int k=0,kmax=10;    return ascdiff;
   double l1;  }
   
   fx=func(x);  /*************** powell ************************/
   for (i=1;i<=npar;i++) p2[i]=x[i];  void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
   for(l=0 ; l <=lmax; l++){              double (*func)(double [])) 
     l1=pow(10,l);  { 
     delts=delt;    void linmin(double p[], double xi[], int n, double *fret, 
     for(k=1 ; k <kmax; k=k+1){                double (*func)(double [])); 
       delt = delta*(l1*k);    int i,ibig,j; 
       p2[theta]=x[theta] +delt;    double del,t,*pt,*ptt,*xit;
       k1=func(p2)-fx;    double fp,fptt;
       p2[theta]=x[theta]-delt;    double *xits;
       k2=func(p2)-fx;    int niterf, itmp;
       /*res= (k1-2.0*fx+k2)/delt/delt; */  
       res= (k1+k2)/delt/delt/2.; /* Divided by because L and not 2*L */    pt=vector(1,n); 
          ptt=vector(1,n); 
 #ifdef DEBUG    xit=vector(1,n); 
       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);    xits=vector(1,n); 
 #endif    *fret=(*func)(p); 
       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */    for (j=1;j<=n;j++) pt[j]=p[j]; 
       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){    for (*iter=1;;++(*iter)) { 
         k=kmax;      fp=(*fret); 
       }      ibig=0; 
       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */      del=0.0; 
         k=kmax; l=lmax*10.;      last_time=curr_time;
       }      (void) gettimeofday(&curr_time,&tzp);
       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){      printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, curr_time.tv_sec-last_time.tv_sec, curr_time.tv_sec-start_time.tv_sec);fflush(stdout);
         delts=delt;      /*    fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, curr_time.tv_sec-last_time.tv_sec, curr_time.tv_sec-start_time.tv_sec);
       }      fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tv_sec-start_time.tv_sec);
     }      */
   }     for (i=1;i<=n;i++) {
   delti[theta]=delts;        printf(" %d %.12f",i, p[i]);
   return res;        fprintf(ficlog," %d %.12lf",i, p[i]);
          fprintf(ficrespow," %.12lf", p[i]);
 }      }
       printf("\n");
 double hessij( double x[], double delti[], int thetai,int thetaj)      fprintf(ficlog,"\n");
 {      fprintf(ficrespow,"\n");fflush(ficrespow);
   int i;      if(*iter <=3){
   int l=1, l1, lmax=20;        tm = *localtime(&curr_time.tv_sec);
   double k1,k2,k3,k4,res,fx;        strcpy(strcurr,asctime(&tm));
   double p2[NPARMAX+1];  /*       asctime_r(&tm,strcurr); */
   int k;        forecast_time=curr_time; 
         itmp = strlen(strcurr);
   fx=func(x);        if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
   for (k=1; k<=2; k++) {          strcurr[itmp-1]='\0';
     for (i=1;i<=npar;i++) p2[i]=x[i];        printf("\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,curr_time.tv_sec-last_time.tv_sec);
     p2[thetai]=x[thetai]+delti[thetai]/k;        fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,curr_time.tv_sec-last_time.tv_sec);
     p2[thetaj]=x[thetaj]+delti[thetaj]/k;        for(niterf=10;niterf<=30;niterf+=10){
     k1=func(p2)-fx;          forecast_time.tv_sec=curr_time.tv_sec+(niterf-*iter)*(curr_time.tv_sec-last_time.tv_sec);
            tmf = *localtime(&forecast_time.tv_sec);
     p2[thetai]=x[thetai]+delti[thetai]/k;  /*      asctime_r(&tmf,strfor); */
     p2[thetaj]=x[thetaj]-delti[thetaj]/k;          strcpy(strfor,asctime(&tmf));
     k2=func(p2)-fx;          itmp = strlen(strfor);
            if(strfor[itmp-1]=='\n')
     p2[thetai]=x[thetai]-delti[thetai]/k;          strfor[itmp-1]='\0';
     p2[thetaj]=x[thetaj]+delti[thetaj]/k;          printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(forecast_time.tv_sec-curr_time.tv_sec,tmpout),strfor,strcurr);
     k3=func(p2)-fx;          fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(forecast_time.tv_sec-curr_time.tv_sec,tmpout),strfor,strcurr);
          }
     p2[thetai]=x[thetai]-delti[thetai]/k;      }
     p2[thetaj]=x[thetaj]-delti[thetaj]/k;      for (i=1;i<=n;i++) { 
     k4=func(p2)-fx;        for (j=1;j<=n;j++) xit[j]=xi[j][i]; 
     res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /* Because of L not 2*L */        fptt=(*fret); 
 #ifdef DEBUG  #ifdef DEBUG
     printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);        printf("fret=%lf \n",*fret);
 #endif        fprintf(ficlog,"fret=%lf \n",*fret);
   }  #endif
   return res;        printf("%d",i);fflush(stdout);
 }        fprintf(ficlog,"%d",i);fflush(ficlog);
         linmin(p,xit,n,fret,func); 
 /************** Inverse of matrix **************/        if (fabs(fptt-(*fret)) > del) { 
 void ludcmp(double **a, int n, int *indx, double *d)          del=fabs(fptt-(*fret)); 
 {          ibig=i; 
   int i,imax,j,k;        } 
   double big,dum,sum,temp;  #ifdef DEBUG
   double *vv;        printf("%d %.12e",i,(*fret));
          fprintf(ficlog,"%d %.12e",i,(*fret));
   vv=vector(1,n);        for (j=1;j<=n;j++) {
   *d=1.0;          xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
   for (i=1;i<=n;i++) {          printf(" x(%d)=%.12e",j,xit[j]);
     big=0.0;          fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
     for (j=1;j<=n;j++)        }
       if ((temp=fabs(a[i][j])) > big) big=temp;        for(j=1;j<=n;j++) {
     if (big == 0.0) nrerror("Singular matrix in routine ludcmp");          printf(" p=%.12e",p[j]);
     vv[i]=1.0/big;          fprintf(ficlog," p=%.12e",p[j]);
   }        }
   for (j=1;j<=n;j++) {        printf("\n");
     for (i=1;i<j;i++) {        fprintf(ficlog,"\n");
       sum=a[i][j];  #endif
       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j];      } 
       a[i][j]=sum;      if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) {
     }  #ifdef DEBUG
     big=0.0;        int k[2],l;
     for (i=j;i<=n;i++) {        k[0]=1;
       sum=a[i][j];        k[1]=-1;
       for (k=1;k<j;k++)        printf("Max: %.12e",(*func)(p));
         sum -= a[i][k]*a[k][j];        fprintf(ficlog,"Max: %.12e",(*func)(p));
       a[i][j]=sum;        for (j=1;j<=n;j++) {
       if ( (dum=vv[i]*fabs(sum)) >= big) {          printf(" %.12e",p[j]);
         big=dum;          fprintf(ficlog," %.12e",p[j]);
         imax=i;        }
       }        printf("\n");
     }        fprintf(ficlog,"\n");
     if (j != imax) {        for(l=0;l<=1;l++) {
       for (k=1;k<=n;k++) {          for (j=1;j<=n;j++) {
         dum=a[imax][k];            ptt[j]=p[j]+(p[j]-pt[j])*k[l];
         a[imax][k]=a[j][k];            printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
         a[j][k]=dum;            fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
       }          }
       *d = -(*d);          printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
       vv[imax]=vv[j];          fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
     }        }
     indx[j]=imax;  #endif
     if (a[j][j] == 0.0) a[j][j]=TINY;  
     if (j != n) {  
       dum=1.0/(a[j][j]);        free_vector(xit,1,n); 
       for (i=j+1;i<=n;i++) a[i][j] *= dum;        free_vector(xits,1,n); 
     }        free_vector(ptt,1,n); 
   }        free_vector(pt,1,n); 
   free_vector(vv,1,n);  /* Doesn't work */        return; 
 ;      } 
 }      if (*iter == ITMAX) nrerror("powell exceeding maximum iterations."); 
       for (j=1;j<=n;j++) { 
 void lubksb(double **a, int n, int *indx, double b[])        ptt[j]=2.0*p[j]-pt[j]; 
 {        xit[j]=p[j]-pt[j]; 
   int i,ii=0,ip,j;        pt[j]=p[j]; 
   double sum;      } 
        fptt=(*func)(ptt); 
   for (i=1;i<=n;i++) {      if (fptt < fp) { 
     ip=indx[i];        t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); 
     sum=b[ip];        if (t < 0.0) { 
     b[ip]=b[i];          linmin(p,xit,n,fret,func); 
     if (ii)          for (j=1;j<=n;j++) { 
       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j];            xi[j][ibig]=xi[j][n]; 
     else if (sum) ii=i;            xi[j][n]=xit[j]; 
     b[i]=sum;          }
   }  #ifdef DEBUG
   for (i=n;i>=1;i--) {          printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
     sum=b[i];          fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j];          for(j=1;j<=n;j++){
     b[i]=sum/a[i][i];            printf(" %.12e",xit[j]);
   }            fprintf(ficlog," %.12e",xit[j]);
 }          }
           printf("\n");
 /************ Frequencies ********************/          fprintf(ficlog,"\n");
 void  freqsummary(char fileres[], int agemin, int agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax)  #endif
 {  /* Some frequencies */        }
        } 
   int i, m, jk, k1, i1, j1, bool, z1,z2,j;    } 
   double ***freq; /* Frequencies */  } 
   double *pp;  
   double pos;  /**** Prevalence limit (stable or period prevalence)  ****************/
   FILE *ficresp;  
   char fileresp[FILENAMELENGTH];  double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int ij)
   {
   pp=vector(1,nlstate);    /* Computes the prevalence limit in each live state at age x by left multiplying the unit
        matrix by transitions matrix until convergence is reached */
   strcpy(fileresp,"p");  
   strcat(fileresp,fileres);    int i, ii,j,k;
   if((ficresp=fopen(fileresp,"w"))==NULL) {    double min, max, maxmin, maxmax,sumnew=0.;
     printf("Problem with prevalence resultfile: %s\n", fileresp);    double **matprod2();
     exit(0);    double **out, cov[NCOVMAX], **pmij();
   }    double **newm;
   freq= ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,agemin,agemax+3);    double agefin, delaymax=50 ; /* Max number of years to converge */
   j1=0;  
     for (ii=1;ii<=nlstate+ndeath;ii++)
   j=cptcovn;      for (j=1;j<=nlstate+ndeath;j++){
   if (cptcovn<1) {j=1;ncodemax[1]=1;}        oldm[ii][j]=(ii==j ? 1.0 : 0.0);
       }
   for(k1=1; k1<=j;k1++){  
    for(i1=1; i1<=ncodemax[k1];i1++){     cov[1]=1.;
        j1++;   
    /* Even if hstepm = 1, at least one multiplication by the unit matrix */
         for (i=-1; i<=nlstate+ndeath; i++)      for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
          for (jk=-1; jk<=nlstate+ndeath; jk++)        newm=savm;
            for(m=agemin; m <= agemax+3; m++)      /* Covariates have to be included here again */
              freq[i][jk][m]=0;       cov[2]=agefin;
            
        for (i=1; i<=imx; i++) {        for (k=1; k<=cptcovn;k++) {
          bool=1;          cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]];
          if  (cptcovn>0) {          /*      printf("ij=%d k=%d Tvar[k]=%d nbcode=%d cov=%lf codtab[ij][Tvar[k]]=%d \n",ij,k, Tvar[k],nbcode[Tvar[k]][codtab[ij][Tvar[k]]],cov[2+k], codtab[ij][Tvar[k]]);*/
            for (z1=1; z1<=cptcovn; z1++)        }
              if (covar[Tvar[z1]][i]!= nbcode[Tvar[z1]][codtab[j1][z1]]) bool=0;        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];
          }        for (k=1; k<=cptcovprod;k++)
           if (bool==1) {          cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];
            for(m=firstpass; m<=lastpass-1; m++){  
              if(agev[m][i]==0) agev[m][i]=agemax+1;        /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
              if(agev[m][i]==1) agev[m][i]=agemax+2;        /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
              freq[s[m][i]][s[m+1][i]][(int)agev[m][i]] += weight[i];        /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
              freq[s[m][i]][s[m+1][i]][(int) agemax+3] += weight[i];      out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
            }  
          }      savm=oldm;
        }      oldm=newm;
         if  (cptcovn>0) {      maxmax=0.;
          fprintf(ficresp, "\n#Variable");      for(j=1;j<=nlstate;j++){
          for (z1=1; z1<=cptcovn; z1++) fprintf(ficresp, " V%d=%d",Tvar[z1],nbcode[Tvar[z1]][codtab[j1][z1]]);        min=1.;
        }        max=0.;
        fprintf(ficresp, "\n#");        for(i=1; i<=nlstate; i++) {
        for(i=1; i<=nlstate;i++)          sumnew=0;
          fprintf(ficresp, " Age Prev(%d) N(%d) N",i,i);          for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
        fprintf(ficresp, "\n");          prlim[i][j]= newm[i][j]/(1-sumnew);
                  max=FMAX(max,prlim[i][j]);
   for(i=(int)agemin; i <= (int)agemax+3; i++){          min=FMIN(min,prlim[i][j]);
     if(i==(int)agemax+3)        }
       printf("Total");        maxmin=max-min;
     else        maxmax=FMAX(maxmax,maxmin);
       printf("Age %d", i);      }
     for(jk=1; jk <=nlstate ; jk++){      if(maxmax < ftolpl){
       for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)        return prlim;
         pp[jk] += freq[jk][m][i];      }
     }    }
     for(jk=1; jk <=nlstate ; jk++){  }
       for(m=-1, pos=0; m <=0 ; m++)  
         pos += freq[jk][m][i];  /*************** transition probabilities ***************/ 
       if(pp[jk]>=1.e-10)  
         printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);  double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
       else  {
         printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);    double s1, s2;
     }    /*double t34;*/
     for(jk=1; jk <=nlstate ; jk++){    int i,j,j1, nc, ii, jj;
       for(m=1, pp[jk]=0; m <=nlstate+ndeath; m++)  
         pp[jk] += freq[jk][m][i];      for(i=1; i<= nlstate; i++){
     }        for(j=1; j<i;j++){
     for(jk=1,pos=0; jk <=nlstate ; jk++)          for (nc=1, s2=0.;nc <=ncovmodel; nc++){
       pos += pp[jk];            /*s2 += param[i][j][nc]*cov[nc];*/
     for(jk=1; jk <=nlstate ; jk++){            s2 += x[(i-1)*nlstate*ncovmodel+(j-1)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];
       if(pos>=1.e-5)  /*       printf("Int j<i s1=%.17e, s2=%.17e\n",s1,s2); */
         printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);          }
       else          ps[i][j]=s2;
         printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);  /*      printf("s1=%.17e, s2=%.17e\n",s1,s2); */
       if( i <= (int) agemax){        }
         if(pos>=1.e-5)        for(j=i+1; j<=nlstate+ndeath;j++){
           fprintf(ficresp," %d %.5f %.0f %.0f",i,pp[jk]/pos, pp[jk],pos);          for (nc=1, s2=0.;nc <=ncovmodel; nc++){
       else            s2 += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];
           fprintf(ficresp," %d NaNq %.0f %.0f",i,pp[jk],pos);  /*        printf("Int j>i s1=%.17e, s2=%.17e %lx %lx\n",s1,s2,s1,s2); */
       }          }
     }          ps[i][j]=s2;
     for(jk=-1; jk <=nlstate+ndeath; jk++)        }
       for(m=-1; m <=nlstate+ndeath; m++)      }
         if(freq[jk][m][i] !=0 ) printf(" %d%d=%.0f",jk,m,freq[jk][m][i]);      /*ps[3][2]=1;*/
     if(i <= (int) agemax)      
       fprintf(ficresp,"\n");      for(i=1; i<= nlstate; i++){
     printf("\n");        s1=0;
     }        for(j=1; j<i; j++)
     }          s1+=exp(ps[i][j]);
  }        for(j=i+1; j<=nlstate+ndeath; j++)
            s1+=exp(ps[i][j]);
   fclose(ficresp);        ps[i][i]=1./(s1+1.);
   free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath,(int) agemin,(int) agemax+3);        for(j=1; j<i; j++)
   free_vector(pp,1,nlstate);          ps[i][j]= exp(ps[i][j])*ps[i][i];
         for(j=i+1; j<=nlstate+ndeath; j++)
 }  /* End of Freq */          ps[i][j]= exp(ps[i][j])*ps[i][i];
         /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
 /************* Waves Concatenation ***************/      } /* end i */
       
 void  concatwav(int wav[], int **dh, int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)      for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
 {        for(jj=1; jj<= nlstate+ndeath; jj++){
   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.          ps[ii][jj]=0;
      Death is a valid wave (if date is known).          ps[ii][ii]=1;
      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i        }
      dh[m][i] of dh[mw[mi][i][i] is the delay between two effective waves m=mw[mi][i]      }
      and mw[mi+1][i]. dh depends on stepm.      
      */  
   /*        for(ii=1; ii<= nlstate+ndeath; ii++){ */
   int i, mi, m;  /*       for(jj=1; jj<= nlstate+ndeath; jj++){ */
   int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;  /*         printf("ddd %lf ",ps[ii][jj]); */
 float sum=0.;  /*       } */
   /*       printf("\n "); */
   for(i=1; i<=imx; i++){  /*        } */
     mi=0;  /*        printf("\n ");printf("%lf ",cov[2]); */
     m=firstpass;         /*
     while(s[m][i] <= nlstate){        for(i=1; i<= npar; i++) printf("%f ",x[i]);
       if(s[m][i]>=1)        goto end;*/
         mw[++mi][i]=m;      return ps;
       if(m >=lastpass)  }
         break;  
       else  /**************** Product of 2 matrices ******************/
         m++;  
     }/* end while */  double **matprod2(double **out, double **in,long nrl, long nrh, long ncl, long nch, long ncolol, long ncoloh, double **b)
     if (s[m][i] > nlstate){  {
       mi++;     /* Death is another wave */    /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
       /* if(mi==0)  never been interviewed correctly before death */       b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
          /* Only death is a correct wave */    /* in, b, out are matrice of pointers which should have been initialized 
       mw[mi][i]=m;       before: only the contents of out is modified. The function returns
     }       a pointer to pointers identical to out */
     long i, j, k;
     wav[i]=mi;    for(i=nrl; i<= nrh; i++)
     if(mi==0)      for(k=ncolol; k<=ncoloh; k++)
       printf("Warning, no any valid information for:%d line=%d\n",num[i],i);        for(j=ncl,out[i][k]=0.; j<=nch; j++)
   }          out[i][k] +=in[i][j]*b[j][k];
   
   for(i=1; i<=imx; i++){    return out;
     for(mi=1; mi<wav[i];mi++){  }
       if (stepm <=0)  
         dh[mi][i]=1;  
       else{  /************* Higher Matrix Product ***************/
         if (s[mw[mi+1][i]][i] > nlstate) {  
           j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12);  double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij )
           if(j=0) j=1;  /* Survives at least one month after exam */  {
         }    /* Computes the transition matrix starting at age 'age' over 
         else{       'nhstepm*hstepm*stepm' months (i.e. until
           j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));       age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
           k=k+1;       nhstepm*hstepm matrices. 
           if (j >= jmax) jmax=j;       Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
           else if (j <= jmin)jmin=j;       (typically every 2 years instead of every month which is too big 
           sum=sum+j;       for the memory).
         }       Model is determined by parameters x and covariates have to be 
         jk= j/stepm;       included manually here. 
         jl= j -jk*stepm;  
         ju= j -(jk+1)*stepm;       */
         if(jl <= -ju)  
           dh[mi][i]=jk;    int i, j, d, h, k;
         else    double **out, cov[NCOVMAX];
           dh[mi][i]=jk+1;    double **newm;
         if(dh[mi][i]==0)  
           dh[mi][i]=1; /* At least one step */    /* Hstepm could be zero and should return the unit matrix */
       }    for (i=1;i<=nlstate+ndeath;i++)
     }      for (j=1;j<=nlstate+ndeath;j++){
   }        oldm[i][j]=(i==j ? 1.0 : 0.0);
   printf("Delay (in months) between two waves Min=%d Max=%d Mean=%f\n\n ",jmin, jmax,sum/k);        po[i][j][0]=(i==j ? 1.0 : 0.0);
 }      }
 /*********** Tricode ****************************/    /* Even if hstepm = 1, at least one multiplication by the unit matrix */
 void tricode(int *Tvar, int **nbcode, int imx)    for(h=1; h <=nhstepm; h++){
 {      for(d=1; d <=hstepm; d++){
   int Ndum[80],ij, k, j, i;        newm=savm;
   int cptcode=0;        /* Covariates have to be included here again */
   for (k=0; k<79; k++) Ndum[k]=0;        cov[1]=1.;
   for (k=1; k<=7; k++) ncodemax[k]=0;        cov[2]=age+((h-1)*hstepm + (d-1))*stepm/YEARM;
          for (k=1; k<=cptcovn;k++) cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]];
   for (j=1; j<=cptcovn; j++) {        for (k=1; k<=cptcovage;k++)
     for (i=1; i<=imx; i++) {          cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];
       ij=(int)(covar[Tvar[j]][i]);        for (k=1; k<=cptcovprod;k++)
       Ndum[ij]++;          cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];
       if (ij > cptcode) cptcode=ij;  
     }  
     /*printf("cptcode=%d cptcovn=%d ",cptcode,cptcovn);*/        /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
     for (i=0; i<=cptcode; i++) {        /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
       if(Ndum[i]!=0) ncodemax[j]++;        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
     }                     pmij(pmmij,cov,ncovmodel,x,nlstate));
          savm=oldm;
     ij=1;        oldm=newm;
     for (i=1; i<=ncodemax[j]; i++) {      }
       for (k=0; k<=79; k++) {      for(i=1; i<=nlstate+ndeath; i++)
         if (Ndum[k] != 0) {        for(j=1;j<=nlstate+ndeath;j++) {
           nbcode[Tvar[j]][ij]=k;          po[i][j][h]=newm[i][j];
           ij++;          /*printf("i=%d j=%d h=%d po[i][j][h]=%f ",i,j,h,po[i][j][h]);
         }           */
         if (ij > ncodemax[j]) break;        }
       }      } /* end h */
     }    return po;
   }    }
   
   }  
   /*************** log-likelihood *************/
 /*********** Health Expectancies ****************/  double func( double *x)
   {
 void evsij(char fileres[], double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int ij)    int i, ii, j, k, mi, d, kk;
 {    double l, ll[NLSTATEMAX], cov[NCOVMAX];
   /* Health expectancies */    double **out;
   int i, j, nhstepm, hstepm, h;    double sw; /* Sum of weights */
   double age, agelim,hf;    double lli; /* Individual log likelihood */
   double ***p3mat;    int s1, s2;
      double bbh, survp;
   fprintf(ficreseij,"# Health expectancies\n");    long ipmx;
   fprintf(ficreseij,"# Age");    /*extern weight */
   for(i=1; i<=nlstate;i++)    /* We are differentiating ll according to initial status */
     for(j=1; j<=nlstate;j++)    /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
       fprintf(ficreseij," %1d-%1d",i,j);    /*for(i=1;i<imx;i++) 
   fprintf(ficreseij,"\n");      printf(" %d\n",s[4][i]);
     */
   hstepm=1*YEARM; /*  Every j years of age (in month) */    cov[1]=1.;
   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */  
     for(k=1; k<=nlstate; k++) ll[k]=0.;
   agelim=AGESUP;  
   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */    if(mle==1){
     /* nhstepm age range expressed in number of stepm */      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
     nhstepm=(int) rint((agelim-age)*YEARM/stepm);        for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
     /* Typically if 20 years = 20*12/6=40 stepm */        for(mi=1; mi<= wav[i]-1; mi++){
     if (stepm >= YEARM) hstepm=1;          for (ii=1;ii<=nlstate+ndeath;ii++)
     nhstepm = nhstepm/hstepm;/* Expressed in hstepm, typically 40/4=10 */            for (j=1;j<=nlstate+ndeath;j++){
     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
     /* Computed by stepm unit matrices, product of hstepm matrices, stored              savm[ii][j]=(ii==j ? 1.0 : 0.0);
        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */            }
     hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, ij);            for(d=0; d<dh[mi][i]; d++){
             newm=savm;
             cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
     for(i=1; i<=nlstate;i++)            for (kk=1; kk<=cptcovage;kk++) {
       for(j=1; j<=nlstate;j++)              cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
         for (h=0, eij[i][j][(int)age]=0; h<=nhstepm; h++){            }
           eij[i][j][(int)age] +=p3mat[i][j][h];            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
         }                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                savm=oldm;
     hf=1;            oldm=newm;
     if (stepm >= YEARM) hf=stepm/YEARM;          } /* end mult */
     fprintf(ficreseij,"%.0f",age );        
     for(i=1; i<=nlstate;i++)          /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
       for(j=1; j<=nlstate;j++){          /* But now since version 0.9 we anticipate for bias at large stepm.
         fprintf(ficreseij," %.4f", hf*eij[i][j][(int)age]);           * If stepm is larger than one month (smallest stepm) and if the exact delay 
       }           * (in months) between two waves is not a multiple of stepm, we rounded to 
     fprintf(ficreseij,"\n");           * the nearest (and in case of equal distance, to the lowest) interval but now
     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);           * we keep into memory the bias bh[mi][i] and also the previous matrix product
   }           * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
 }           * probability in order to take into account the bias as a fraction of the way
            * from savm to out if bh is negative or even beyond if bh is positive. bh varies
 /************ Variance ******************/           * -stepm/2 to stepm/2 .
 void varevsij(char fileres[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij)           * For stepm=1 the results are the same as for previous versions of Imach.
 {           * For stepm > 1 the results are less biased than in previous versions. 
   /* Variance of health expectancies */           */
   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/          s1=s[mw[mi][i]][i];
   double **newm;          s2=s[mw[mi+1][i]][i];
   double **dnewm,**doldm;          bbh=(double)bh[mi][i]/(double)stepm; 
   int i, j, nhstepm, hstepm, h;          /* bias bh is positive if real duration
   int k, cptcode;           * is higher than the multiple of stepm and negative otherwise.
    double *xp;           */
   double **gp, **gm;          /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
   double ***gradg, ***trgradg;          if( s2 > nlstate){ 
   double ***p3mat;            /* i.e. if s2 is a death state and if the date of death is known 
   double age,agelim;               then the contribution to the likelihood is the probability to 
   int theta;               die between last step unit time and current  step unit time, 
                which is also equal to probability to die before dh 
    fprintf(ficresvij,"# Covariances of life expectancies\n");               minus probability to die before dh-stepm . 
   fprintf(ficresvij,"# Age");               In version up to 0.92 likelihood was computed
   for(i=1; i<=nlstate;i++)          as if date of death was unknown. Death was treated as any other
     for(j=1; j<=nlstate;j++)          health state: the date of the interview describes the actual state
       fprintf(ficresvij," Cov(e%1d, e%1d)",i,j);          and not the date of a change in health state. The former idea was
   fprintf(ficresvij,"\n");          to consider that at each interview the state was recorded
           (healthy, disable or death) and IMaCh was corrected; but when we
   xp=vector(1,npar);          introduced the exact date of death then we should have modified
   dnewm=matrix(1,nlstate,1,npar);          the contribution of an exact death to the likelihood. This new
   doldm=matrix(1,nlstate,1,nlstate);          contribution is smaller and very dependent of the step unit
            stepm. It is no more the probability to die between last interview
   hstepm=1*YEARM; /* Every year of age */          and month of death but the probability to survive from last
   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */          interview up to one month before death multiplied by the
   agelim = AGESUP;          probability to die within a month. Thanks to Chris
   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */          Jackson for correcting this bug.  Former versions increased
     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */          mortality artificially. The bad side is that we add another loop
     if (stepm >= YEARM) hstepm=1;          which slows down the processing. The difference can be up to 10%
     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */          lower mortality.
     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);            */
     gradg=ma3x(0,nhstepm,1,npar,1,nlstate);            lli=log(out[s1][s2] - savm[s1][s2]);
     gp=matrix(0,nhstepm,1,nlstate);  
     gm=matrix(0,nhstepm,1,nlstate);  
           } else if  (s2==-2) {
     for(theta=1; theta <=npar; theta++){            for (j=1,survp=0. ; j<=nlstate; j++) 
       for(i=1; i<=npar; i++){ /* Computes gradient */              survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
         xp[i] = x[i] + (i==theta ?delti[theta]:0);            /*survp += out[s1][j]; */
       }            lli= log(survp);
       hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);            }
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);          
       for(j=1; j<= nlstate; j++){          else if  (s2==-4) { 
         for(h=0; h<=nhstepm; h++){            for (j=3,survp=0. ; j<=nlstate; j++)  
           for(i=1, gp[h][j]=0.;i<=nlstate;i++)              survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
             gp[h][j] += prlim[i][i]*p3mat[i][j][h];            lli= log(survp); 
         }          } 
       }  
              else if  (s2==-5) { 
       for(i=1; i<=npar; i++) /* Computes gradient */            for (j=1,survp=0. ; j<=2; j++)  
         xp[i] = x[i] - (i==theta ?delti[theta]:0);              survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
       hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);              lli= log(survp); 
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);          } 
       for(j=1; j<= nlstate; j++){          
         for(h=0; h<=nhstepm; h++){          else{
           for(i=1, gm[h][j]=0.;i<=nlstate;i++)            lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
             gm[h][j] += prlim[i][i]*p3mat[i][j][h];            /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
         }          } 
       }          /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
       for(j=1; j<= nlstate; j++)          /*if(lli ==000.0)*/
         for(h=0; h<=nhstepm; h++){          /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];          ipmx +=1;
         }          sw += weight[i];
     } /* End theta */          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
         } /* end of wave */
     trgradg =ma3x(0,nhstepm,1,nlstate,1,npar);      } /* end of individual */
     }  else if(mle==2){
     for(h=0; h<=nhstepm; h++)      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
       for(j=1; j<=nlstate;j++)        for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
         for(theta=1; theta <=npar; theta++)        for(mi=1; mi<= wav[i]-1; mi++){
           trgradg[h][j][theta]=gradg[h][theta][j];          for (ii=1;ii<=nlstate+ndeath;ii++)
             for (j=1;j<=nlstate+ndeath;j++){
     for(i=1;i<=nlstate;i++)              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
       for(j=1;j<=nlstate;j++)              savm[ii][j]=(ii==j ? 1.0 : 0.0);
         vareij[i][j][(int)age] =0.;            }
     for(h=0;h<=nhstepm;h++){          for(d=0; d<=dh[mi][i]; d++){
       for(k=0;k<=nhstepm;k++){            newm=savm;
         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);            cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);            for (kk=1; kk<=cptcovage;kk++) {
         for(i=1;i<=nlstate;i++)              cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
           for(j=1;j<=nlstate;j++)            }
             vareij[i][j][(int)age] += doldm[i][j];            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
       }                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
     }            savm=oldm;
     h=1;            oldm=newm;
     if (stepm >= YEARM) h=stepm/YEARM;          } /* end mult */
     fprintf(ficresvij,"%.0f ",age );        
     for(i=1; i<=nlstate;i++)          s1=s[mw[mi][i]][i];
       for(j=1; j<=nlstate;j++){          s2=s[mw[mi+1][i]][i];
         fprintf(ficresvij," %.4f", h*vareij[i][j][(int)age]);          bbh=(double)bh[mi][i]/(double)stepm; 
       }          lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
     fprintf(ficresvij,"\n");          ipmx +=1;
     free_matrix(gp,0,nhstepm,1,nlstate);          sw += weight[i];
     free_matrix(gm,0,nhstepm,1,nlstate);          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
     free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);        } /* end of wave */
     free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);      } /* end of individual */
     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);    }  else if(mle==3){  /* exponential inter-extrapolation */
   } /* End age */      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
          for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
   free_vector(xp,1,npar);        for(mi=1; mi<= wav[i]-1; mi++){
   free_matrix(doldm,1,nlstate,1,npar);          for (ii=1;ii<=nlstate+ndeath;ii++)
   free_matrix(dnewm,1,nlstate,1,nlstate);            for (j=1;j<=nlstate+ndeath;j++){
               oldm[ii][j]=(ii==j ? 1.0 : 0.0);
 }              savm[ii][j]=(ii==j ? 1.0 : 0.0);
             }
 /************ Variance of prevlim ******************/          for(d=0; d<dh[mi][i]; d++){
 void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij)            newm=savm;
 {            cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
   /* Variance of prevalence limit */            for (kk=1; kk<=cptcovage;kk++) {
   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/              cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
   double **newm;            }
   double **dnewm,**doldm;            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
   int i, j, nhstepm, hstepm;                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
   int k, cptcode;            savm=oldm;
   double *xp;            oldm=newm;
   double *gp, *gm;          } /* end mult */
   double **gradg, **trgradg;        
   double age,agelim;          s1=s[mw[mi][i]][i];
   int theta;          s2=s[mw[mi+1][i]][i];
              bbh=(double)bh[mi][i]/(double)stepm; 
   fprintf(ficresvpl,"# Standard deviation of prevalences limit\n");          lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
   fprintf(ficresvpl,"# Age");          ipmx +=1;
   for(i=1; i<=nlstate;i++)          sw += weight[i];
       fprintf(ficresvpl," %1d-%1d",i,i);          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
   fprintf(ficresvpl,"\n");        } /* end of wave */
       } /* end of individual */
   xp=vector(1,npar);    }else if (mle==4){  /* ml=4 no inter-extrapolation */
   dnewm=matrix(1,nlstate,1,npar);      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
   doldm=matrix(1,nlstate,1,nlstate);        for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
          for(mi=1; mi<= wav[i]-1; mi++){
   hstepm=1*YEARM; /* Every year of age */          for (ii=1;ii<=nlstate+ndeath;ii++)
   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */            for (j=1;j<=nlstate+ndeath;j++){
   agelim = AGESUP;              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */              savm[ii][j]=(ii==j ? 1.0 : 0.0);
     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */            }
     if (stepm >= YEARM) hstepm=1;          for(d=0; d<dh[mi][i]; d++){
     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */            newm=savm;
     gradg=matrix(1,npar,1,nlstate);            cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
     gp=vector(1,nlstate);            for (kk=1; kk<=cptcovage;kk++) {
     gm=vector(1,nlstate);              cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
             }
     for(theta=1; theta <=npar; theta++){          
       for(i=1; i<=npar; i++){ /* Computes gradient */            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
         xp[i] = x[i] + (i==theta ?delti[theta]:0);                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
       }            savm=oldm;
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);            oldm=newm;
       for(i=1;i<=nlstate;i++)          } /* end mult */
         gp[i] = prlim[i][i];        
              s1=s[mw[mi][i]][i];
       for(i=1; i<=npar; i++) /* Computes gradient */          s2=s[mw[mi+1][i]][i];
         xp[i] = x[i] - (i==theta ?delti[theta]:0);          if( s2 > nlstate){ 
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);            lli=log(out[s1][s2] - savm[s1][s2]);
       for(i=1;i<=nlstate;i++)          }else{
         gm[i] = prlim[i][i];            lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
           }
       for(i=1;i<=nlstate;i++)          ipmx +=1;
         gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];          sw += weight[i];
     } /* End theta */          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
   /*      printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
     trgradg =matrix(1,nlstate,1,npar);        } /* end of wave */
       } /* end of individual */
     for(j=1; j<=nlstate;j++)    }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
       for(theta=1; theta <=npar; theta++)      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
         trgradg[j][theta]=gradg[theta][j];        for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
         for(mi=1; mi<= wav[i]-1; mi++){
     for(i=1;i<=nlstate;i++)          for (ii=1;ii<=nlstate+ndeath;ii++)
       varpl[i][(int)age] =0.;            for (j=1;j<=nlstate+ndeath;j++){
     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);              savm[ii][j]=(ii==j ? 1.0 : 0.0);
     for(i=1;i<=nlstate;i++)            }
       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */          for(d=0; d<dh[mi][i]; d++){
             newm=savm;
     fprintf(ficresvpl,"%.0f ",age );            cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
     for(i=1; i<=nlstate;i++)            for (kk=1; kk<=cptcovage;kk++) {
       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));              cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
     fprintf(ficresvpl,"\n");            }
     free_vector(gp,1,nlstate);          
     free_vector(gm,1,nlstate);            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
     free_matrix(gradg,1,npar,1,nlstate);                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
     free_matrix(trgradg,1,nlstate,1,npar);            savm=oldm;
   } /* End age */            oldm=newm;
           } /* end mult */
   free_vector(xp,1,npar);        
   free_matrix(doldm,1,nlstate,1,npar);          s1=s[mw[mi][i]][i];
   free_matrix(dnewm,1,nlstate,1,nlstate);          s2=s[mw[mi+1][i]][i];
           lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
 }          ipmx +=1;
           sw += weight[i];
           ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
           /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
 /***********************************************/        } /* end of wave */
 /**************** Main Program *****************/      } /* end of individual */
 /***********************************************/    } /* End of if */
     for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
 /*int main(int argc, char *argv[])*/    /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
 int main()    l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
 {    return -l;
   }
   int i,j, k, n=MAXN,iter,m,size,cptcode, aaa, cptcod;  
   double agedeb, agefin,hf;  /*************** log-likelihood *************/
   double agemin=1.e20, agemax=-1.e20;  double funcone( double *x)
   {
   double fret;    /* Same as likeli but slower because of a lot of printf and if */
   double **xi,tmp,delta;    int i, ii, j, k, mi, d, kk;
     double l, ll[NLSTATEMAX], cov[NCOVMAX];
   double dum; /* Dummy variable */    double **out;
   double ***p3mat;    double lli; /* Individual log likelihood */
   int *indx;    double llt;
   char line[MAXLINE], linepar[MAXLINE];    int s1, s2;
   char title[MAXLINE];    double bbh, survp;
   char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH];    /*extern weight */
   char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filereso[FILENAMELENGTH];    /* We are differentiating ll according to initial status */
   char filerest[FILENAMELENGTH];    /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
   char fileregp[FILENAMELENGTH];    /*for(i=1;i<imx;i++) 
   char path[80],pathc[80],pathcd[80],pathtot[80],model[20];      printf(" %d\n",s[4][i]);
   int firstobs=1, lastobs=10;    */
   int sdeb, sfin; /* Status at beginning and end */    cov[1]=1.;
   int c,  h , cpt,l;  
   int ju,jl, mi;    for(k=1; k<=nlstate; k++) ll[k]=0.;
   int i1,j1, k1,jk,aa,bb, stepsize;  
   int jnais,jdc,jint4,jint1,jint2,jint3,**outcome,**adl,*tab;    for (i=1,ipmx=0, sw=0.; i<=imx; i++){
        for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
   int hstepm, nhstepm;      for(mi=1; mi<= wav[i]-1; mi++){
   double bage, fage, age, agelim, agebase;        for (ii=1;ii<=nlstate+ndeath;ii++)
   double ftolpl=FTOL;          for (j=1;j<=nlstate+ndeath;j++){
   double **prlim;            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
   double *severity;            savm[ii][j]=(ii==j ? 1.0 : 0.0);
   double ***param; /* Matrix of parameters */          }
   double  *p;        for(d=0; d<dh[mi][i]; d++){
   double **matcov; /* Matrix of covariance */          newm=savm;
   double ***delti3; /* Scale */          cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
   double *delti; /* Scale */          for (kk=1; kk<=cptcovage;kk++) {
   double ***eij, ***vareij;            cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
   double **varpl; /* Variances of prevalence limits by age */          }
   double *epj, vepp;          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
   char version[80]="Imach version 0.64, May 2000, INED-EUROREVES ";                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
   char *alph[]={"a","a","b","c","d","e"}, str[4];          savm=oldm;
   char z[1]="c", occ;          oldm=newm;
 #include <sys/time.h>        } /* end mult */
 #include <time.h>        
   char stra[80], strb[80], strc[80], strd[80],stre[80],modelsav[80];        s1=s[mw[mi][i]][i];
   /* long total_usecs;        s2=s[mw[mi+1][i]][i];
   struct timeval start_time, end_time;        bbh=(double)bh[mi][i]/(double)stepm; 
          /* bias is positive if real duration
   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */         * is higher than the multiple of stepm and negative otherwise.
          */
         if( s2 > nlstate && (mle <5) ){  /* Jackson */
   printf("\nIMACH, Version 0.64a");          lli=log(out[s1][s2] - savm[s1][s2]);
   printf("\nEnter the parameter file name: ");        } else if  (s2==-2) {
           for (j=1,survp=0. ; j<=nlstate; j++) 
 #ifdef windows            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
   scanf("%s",pathtot);          lli= log(survp);
   cygwin_split_path(pathtot,path,optionfile);        }else if (mle==1){
      printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
      chdir(path);        } else if(mle==2){
            lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
   /*size=30;        } else if(mle==3){  /* exponential inter-extrapolation */
   getcwd(pathcd, size);            lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
   printf("pathcd=%s, path=%s, optionfile=%s\n",pathcd,path,optionfile);        } else if (mle==4){  /* mle=4 no inter-extrapolation */
   cutv(path,optionfile,pathtot,'\\');          lli=log(out[s1][s2]); /* Original formula */
   chdir(path);        } else{  /* ml>=5 no inter-extrapolation no jackson =0.8a */
   replace(pathc,path);          lli=log(out[s1][s2]); /* Original formula */
   printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);        } /* End of if */
   */        ipmx +=1;
 #endif        sw += weight[i];
 #ifdef unix        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
   scanf("%s",optionfile);  /*       printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
 #endif        if(globpr){
           fprintf(ficresilk,"%9d %6d %2d %2d %1d %1d %3d %11.6f %8.4f\
 /*-------- arguments in the command line --------*/   %11.6f %11.6f %11.6f ", \
                   num[i],i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],
   strcpy(fileres,"r");                  2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
   strcat(fileres, optionfile);          for(k=1,llt=0.,l=0.; k<=nlstate; k++){
             llt +=ll[k]*gipmx/gsw;
   /*---------arguments file --------*/            fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
           }
   if((ficpar=fopen(optionfile,"r"))==NULL)    {          fprintf(ficresilk," %10.6f\n", -llt);
     printf("Problem with optionfile %s\n",optionfile);        }
     goto end;      } /* end of wave */
   }    } /* end of individual */
     for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
   strcpy(filereso,"o");    /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
   strcat(filereso,fileres);    l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
   if((ficparo=fopen(filereso,"w"))==NULL) {    if(globpr==0){ /* First time we count the contributions and weights */
     printf("Problem with Output resultfile: %s\n", filereso);goto end;      gipmx=ipmx;
   }      gsw=sw;
     }
   /* Reads comments: lines beginning with '#' */    return -l;
   while((c=getc(ficpar))=='#' && c!= EOF){  }
     ungetc(c,ficpar);  
     fgets(line, MAXLINE, ficpar);  
     puts(line);  /*************** function likelione ***********/
     fputs(line,ficparo);  void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
   }  {
   ungetc(c,ficpar);    /* This routine should help understanding what is done with 
        the selection of individuals/waves and
   fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncov=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncov, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model);       to check the exact contribution to the likelihood.
   printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncov=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncov, nlstate,ndeath, maxwav, mle, weightopt,model);       Plotting could be done.
   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncov=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncov,nlstate,ndeath,maxwav, mle, weightopt,model);     */
     int k;
   covar=matrix(1,NCOVMAX,1,n);      
   if (strlen(model)<=1) cptcovn=0;    if(*globpri !=0){ /* Just counts and sums, no printings */
   else {      strcpy(fileresilk,"ilk"); 
     j=0;      strcat(fileresilk,fileres);
     j=nbocc(model,'+');      if((ficresilk=fopen(fileresilk,"w"))==NULL) {
     cptcovn=j+1;        printf("Problem with resultfile: %s\n", fileresilk);
   }        fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
       }
   ncovmodel=2+cptcovn;      fprintf(ficresilk, "#individual(line's_record) s1 s2 wave# effective_wave# number_of_matrices_product pij weight -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
   nvar=ncovmodel-1; /* Suppressing age as a basic covariate */      fprintf(ficresilk, "#num_i i s1 s2 mi mw dh likeli weight 2wlli out sav ");
        /*  i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
   /* Read guess parameters */      for(k=1; k<=nlstate; k++) 
   /* Reads comments: lines beginning with '#' */        fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
   while((c=getc(ficpar))=='#' && c!= EOF){      fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
     ungetc(c,ficpar);    }
     fgets(line, MAXLINE, ficpar);  
     puts(line);    *fretone=(*funcone)(p);
     fputs(line,ficparo);    if(*globpri !=0){
   }      fclose(ficresilk);
   ungetc(c,ficpar);      fprintf(fichtm,"\n<br>File of contributions to the likelihood: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
        fflush(fichtm); 
   param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);    } 
     for(i=1; i <=nlstate; i++)    return;
     for(j=1; j <=nlstate+ndeath-1; j++){  }
       fscanf(ficpar,"%1d%1d",&i1,&j1);  
       fprintf(ficparo,"%1d%1d",i1,j1);  
       printf("%1d%1d",i,j);  /*********** Maximum Likelihood Estimation ***************/
       for(k=1; k<=ncovmodel;k++){  
         fscanf(ficpar," %lf",&param[i][j][k]);  void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
         printf(" %lf",param[i][j][k]);  {
         fprintf(ficparo," %lf",param[i][j][k]);    int i,j, iter;
       }    double **xi;
       fscanf(ficpar,"\n");    double fret;
       printf("\n");    double fretone; /* Only one call to likelihood */
       fprintf(ficparo,"\n");    /*  char filerespow[FILENAMELENGTH];*/
     }    xi=matrix(1,npar,1,npar);
      for (i=1;i<=npar;i++)
   npar= (nlstate+ndeath-1)*nlstate*ncovmodel;      for (j=1;j<=npar;j++)
   p=param[1][1];        xi[i][j]=(i==j ? 1.0 : 0.0);
      printf("Powell\n");  fprintf(ficlog,"Powell\n");
   /* Reads comments: lines beginning with '#' */    strcpy(filerespow,"pow"); 
   while((c=getc(ficpar))=='#' && c!= EOF){    strcat(filerespow,fileres);
     ungetc(c,ficpar);    if((ficrespow=fopen(filerespow,"w"))==NULL) {
     fgets(line, MAXLINE, ficpar);      printf("Problem with resultfile: %s\n", filerespow);
     puts(line);      fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
     fputs(line,ficparo);    }
   }    fprintf(ficrespow,"# Powell\n# iter -2*LL");
   ungetc(c,ficpar);    for (i=1;i<=nlstate;i++)
       for(j=1;j<=nlstate+ndeath;j++)
   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
   delti=vector(1,npar); /* Scale of each paramater (output from hesscov) */    fprintf(ficrespow,"\n");
   for(i=1; i <=nlstate; i++){  
     for(j=1; j <=nlstate+ndeath-1; j++){    powell(p,xi,npar,ftol,&iter,&fret,func);
       fscanf(ficpar,"%1d%1d",&i1,&j1);  
       printf("%1d%1d",i,j);    free_matrix(xi,1,npar,1,npar);
       fprintf(ficparo,"%1d%1d",i1,j1);    fclose(ficrespow);
       for(k=1; k<=ncovmodel;k++){    printf("\n#Number of iterations = %d, -2 Log likelihood = %.12f\n",iter,func(p));
         fscanf(ficpar,"%le",&delti3[i][j][k]);    fprintf(ficlog,"\n#Number of iterations = %d, -2 Log likelihood = %.12f \n",iter,func(p));
         printf(" %le",delti3[i][j][k]);    fprintf(ficres,"#Number of iterations = %d, -2 Log likelihood = %.12f \n",iter,func(p));
         fprintf(ficparo," %le",delti3[i][j][k]);  
       }  }
       fscanf(ficpar,"\n");  
       printf("\n");  /**** Computes Hessian and covariance matrix ***/
       fprintf(ficparo,"\n");  void hesscov(double **matcov, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
     }  {
   }    double  **a,**y,*x,pd;
   delti=delti3[1][1];    double **hess;
      int i, j,jk;
   /* Reads comments: lines beginning with '#' */    int *indx;
   while((c=getc(ficpar))=='#' && c!= EOF){  
     ungetc(c,ficpar);    double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
     fgets(line, MAXLINE, ficpar);    double hessij(double p[], double delti[], int i, int j,double (*func)(double []),int npar);
     puts(line);    void lubksb(double **a, int npar, int *indx, double b[]) ;
     fputs(line,ficparo);    void ludcmp(double **a, int npar, int *indx, double *d) ;
   }    double gompertz(double p[]);
   ungetc(c,ficpar);    hess=matrix(1,npar,1,npar);
    
   matcov=matrix(1,npar,1,npar);    printf("\nCalculation of the hessian matrix. Wait...\n");
   for(i=1; i <=npar; i++){    fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
     fscanf(ficpar,"%s",&str);    for (i=1;i<=npar;i++){
     printf("%s",str);      printf("%d",i);fflush(stdout);
     fprintf(ficparo,"%s",str);      fprintf(ficlog,"%d",i);fflush(ficlog);
     for(j=1; j <=i; j++){     
       fscanf(ficpar," %le",&matcov[i][j]);       hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
       printf(" %.5le",matcov[i][j]);      
       fprintf(ficparo," %.5le",matcov[i][j]);      /*  printf(" %f ",p[i]);
     }          printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
     fscanf(ficpar,"\n");    }
     printf("\n");    
     fprintf(ficparo,"\n");    for (i=1;i<=npar;i++) {
   }      for (j=1;j<=npar;j++)  {
   for(i=1; i <=npar; i++)        if (j>i) { 
     for(j=i+1;j<=npar;j++)          printf(".%d%d",i,j);fflush(stdout);
       matcov[i][j]=matcov[j][i];          fprintf(ficlog,".%d%d",i,j);fflush(ficlog);
              hess[i][j]=hessij(p,delti,i,j,func,npar);
   printf("\n");          
           hess[j][i]=hess[i][j];    
           /*printf(" %lf ",hess[i][j]);*/
    if(mle==1){        }
     /*-------- data file ----------*/      }
     if((ficres =fopen(fileres,"w"))==NULL) {    }
       printf("Problem with resultfile: %s\n", fileres);goto end;    printf("\n");
     }    fprintf(ficlog,"\n");
     fprintf(ficres,"#%s\n",version);  
        printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
     if((fic=fopen(datafile,"r"))==NULL)    {    fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
       printf("Problem with datafile: %s\n", datafile);goto end;    
     }    a=matrix(1,npar,1,npar);
     y=matrix(1,npar,1,npar);
     n= lastobs;    x=vector(1,npar);
     severity = vector(1,maxwav);    indx=ivector(1,npar);
     outcome=imatrix(1,maxwav+1,1,n);    for (i=1;i<=npar;i++)
     num=ivector(1,n);      for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
     moisnais=vector(1,n);    ludcmp(a,npar,indx,&pd);
     annais=vector(1,n);  
     moisdc=vector(1,n);    for (j=1;j<=npar;j++) {
     andc=vector(1,n);      for (i=1;i<=npar;i++) x[i]=0;
     agedc=vector(1,n);      x[j]=1;
     cod=ivector(1,n);      lubksb(a,npar,indx,x);
     weight=vector(1,n);      for (i=1;i<=npar;i++){ 
     for(i=1;i<=n;i++) weight[i]=1.0; /* Equal weights, 1 by default */        matcov[i][j]=x[i];
     mint=matrix(1,maxwav,1,n);      }
     anint=matrix(1,maxwav,1,n);    }
     s=imatrix(1,maxwav+1,1,n);  
     adl=imatrix(1,maxwav+1,1,n);        printf("\n#Hessian matrix#\n");
     tab=ivector(1,NCOVMAX);    fprintf(ficlog,"\n#Hessian matrix#\n");
     ncodemax=ivector(1,8);    for (i=1;i<=npar;i++) { 
       for (j=1;j<=npar;j++) { 
     i=1;        printf("%.3e ",hess[i][j]);
     while (fgets(line, MAXLINE, fic) != NULL)    {        fprintf(ficlog,"%.3e ",hess[i][j]);
       if ((i >= firstobs) && (i <=lastobs)) {      }
              printf("\n");
         for (j=maxwav;j>=1;j--){      fprintf(ficlog,"\n");
           cutv(stra, strb,line,' '); s[j][i]=atoi(strb);    }
           strcpy(line,stra);  
           cutv(stra, strb,line,'/'); anint[j][i]=(double)(atoi(strb)); strcpy(line,stra);    /* Recompute Inverse */
           cutv(stra, strb,line,' '); mint[j][i]=(double)(atoi(strb)); strcpy(line,stra);    for (i=1;i<=npar;i++)
         }      for (j=1;j<=npar;j++) a[i][j]=matcov[i][j];
            ludcmp(a,npar,indx,&pd);
         cutv(stra, strb,line,'/'); andc[i]=(double)(atoi(strb)); strcpy(line,stra);  
         cutv(stra, strb,line,' '); moisdc[i]=(double)(atoi(strb)); strcpy(line,stra);    /*  printf("\n#Hessian matrix recomputed#\n");
   
         cutv(stra, strb,line,'/'); annais[i]=(double)(atoi(strb)); strcpy(line,stra);    for (j=1;j<=npar;j++) {
         cutv(stra, strb,line,' '); moisnais[i]=(double)(atoi(strb)); strcpy(line,stra);      for (i=1;i<=npar;i++) x[i]=0;
       x[j]=1;
         cutv(stra, strb,line,' '); weight[i]=(double)(atoi(strb)); strcpy(line,stra);      lubksb(a,npar,indx,x);
         for (j=ncov;j>=1;j--){      for (i=1;i<=npar;i++){ 
           cutv(stra, strb,line,' '); covar[j][i]=(double)(atoi(strb)); strcpy(line,stra);        y[i][j]=x[i];
         }        printf("%.3e ",y[i][j]);
         num[i]=atol(stra);        fprintf(ficlog,"%.3e ",y[i][j]);
       }
         /*printf("%d %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]), (weight[i]), (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i]),  (mint[5][i]), (anint[5][i]), (s[5][i]),  (mint[6][i]), (anint[6][i]), (s[6][i]));*/      printf("\n");
       fprintf(ficlog,"\n");
         i=i+1;    }
       }    */
     }  
     free_matrix(a,1,npar,1,npar);
     /*scanf("%d",i);*/    free_matrix(y,1,npar,1,npar);
   imx=i-1; /* Number of individuals */    free_vector(x,1,npar);
     free_ivector(indx,1,npar);
   /* Calculation of the number of parameter from char model*/    free_matrix(hess,1,npar,1,npar);
   Tvar=ivector(1,8);      
      
   if (strlen(model) >1){  }
     j=0;  
     j=nbocc(model,'+');  /*************** hessian matrix ****************/
     cptcovn=j+1;  double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
      {
     strcpy(modelsav,model);    int i;
     if (j==0) {    int l=1, lmax=20;
       cutv(stra,strb,modelsav,'V'); Tvar[1]=atoi(strb);    double k1,k2;
     }    double p2[NPARMAX+1];
     else {    double res;
       for(i=j; i>=1;i--){    double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
         cutv(stra,strb,modelsav,'+');    double fx;
         if (strchr(strb,'*')) {    int k=0,kmax=10;
           cutv(strd,strc,strb,'*');    double l1;
           cutv(strb,stre,strc,'V');Tvar[i+1]=ncov+1;  
           cutv(strb,strc,strd,'V');    fx=func(x);
           for (k=1; k<=lastobs;k++)    for (i=1;i<=npar;i++) p2[i]=x[i];
             covar[ncov+1][k]=covar[atoi(stre)][k]*covar[atoi(strc)][k];    for(l=0 ; l <=lmax; l++){
         }      l1=pow(10,l);
         else {cutv(strd,strc,strb,'V');      delts=delt;
         Tvar[i+1]=atoi(strc);      for(k=1 ; k <kmax; k=k+1){
         }        delt = delta*(l1*k);
         strcpy(modelsav,stra);          p2[theta]=x[theta] +delt;
       }        k1=func(p2)-fx;
       cutv(strd,strc,stra,'V');        p2[theta]=x[theta]-delt;
       Tvar[1]=atoi(strc);        k2=func(p2)-fx;
     }        /*res= (k1-2.0*fx+k2)/delt/delt; */
   }        res= (k1+k2)/delt/delt/2.; /* Divided by because L and not 2*L */
   /*printf("tvar=%d ",Tvar[1]);        
   scanf("%d ",i);*/  #ifdef DEBUG
     fclose(fic);        printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
         fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
     if (weightopt != 1) { /* Maximisation without weights*/  #endif
       for(i=1;i<=n;i++) weight[i]=1.0;        /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
     }        if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
     /*-calculation of age at interview from date of interview and age at death -*/          k=kmax;
     agev=matrix(1,maxwav,1,imx);        }
            else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
     for (i=1; i<=imx; i++)  {          k=kmax; l=lmax*10.;
       agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);        }
       for(m=1; (m<= maxwav); m++){        else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
         if(s[m][i] >0){          delts=delt;
           if (s[m][i] == nlstate+1) {        }
             if(agedc[i]>0)      }
               if(moisdc[i]!=99 && andc[i]!=9999)    }
               agev[m][i]=agedc[i];    delti[theta]=delts;
             else{    return res; 
               printf("Warning negative age at death: %d line:%d\n",num[i],i);    
               agev[m][i]=-1;  }
             }  
           }  double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
           else if(s[m][i] !=9){ /* Should no more exist */  {
             agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);    int i;
             if(mint[m][i]==99 || anint[m][i]==9999)    int l=1, l1, lmax=20;
               agev[m][i]=1;    double k1,k2,k3,k4,res,fx;
             else if(agev[m][i] <agemin){    double p2[NPARMAX+1];
               agemin=agev[m][i];    int k;
               /*printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], agemin);*/  
             }    fx=func(x);
             else if(agev[m][i] >agemax){    for (k=1; k<=2; k++) {
               agemax=agev[m][i];      for (i=1;i<=npar;i++) p2[i]=x[i];
              /* printf(" anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.0f\n",m,i,anint[m][i], i,annais[i], agemax);*/      p2[thetai]=x[thetai]+delti[thetai]/k;
             }      p2[thetaj]=x[thetaj]+delti[thetaj]/k;
             /*agev[m][i]=anint[m][i]-annais[i];*/      k1=func(p2)-fx;
             /*   agev[m][i] = age[i]+2*m;*/    
           }      p2[thetai]=x[thetai]+delti[thetai]/k;
           else { /* =9 */      p2[thetaj]=x[thetaj]-delti[thetaj]/k;
             agev[m][i]=1;      k2=func(p2)-fx;
             s[m][i]=-1;    
           }      p2[thetai]=x[thetai]-delti[thetai]/k;
         }      p2[thetaj]=x[thetaj]+delti[thetaj]/k;
         else /*= 0 Unknown */      k3=func(p2)-fx;
           agev[m][i]=1;    
       }      p2[thetai]=x[thetai]-delti[thetai]/k;
          p2[thetaj]=x[thetaj]-delti[thetaj]/k;
     }      k4=func(p2)-fx;
     for (i=1; i<=imx; i++)  {      res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /* Because of L not 2*L */
       for(m=1; (m<= maxwav); m++){  #ifdef DEBUG
         if (s[m][i] > (nlstate+ndeath)) {      printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
           printf("Error: Wrong value in nlstate or ndeath\n");        fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
           goto end;  #endif
         }    }
       }    return res;
     }  }
   
 printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, agemin, agemax);  /************** Inverse of matrix **************/
   void ludcmp(double **a, int n, int *indx, double *d) 
     free_vector(severity,1,maxwav);  { 
     free_imatrix(outcome,1,maxwav+1,1,n);    int i,imax,j,k; 
     free_vector(moisnais,1,n);    double big,dum,sum,temp; 
     free_vector(annais,1,n);    double *vv; 
     free_matrix(mint,1,maxwav,1,n);   
     free_matrix(anint,1,maxwav,1,n);    vv=vector(1,n); 
     free_vector(moisdc,1,n);    *d=1.0; 
     free_vector(andc,1,n);    for (i=1;i<=n;i++) { 
       big=0.0; 
          for (j=1;j<=n;j++) 
     wav=ivector(1,imx);        if ((temp=fabs(a[i][j])) > big) big=temp; 
     dh=imatrix(1,lastpass-firstpass+1,1,imx);      if (big == 0.0) nrerror("Singular matrix in routine ludcmp"); 
     mw=imatrix(1,lastpass-firstpass+1,1,imx);      vv[i]=1.0/big; 
        } 
     /* Concatenates waves */    for (j=1;j<=n;j++) { 
       concatwav(wav, dh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);      for (i=1;i<j;i++) { 
         sum=a[i][j]; 
         for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
 Tcode=ivector(1,100);        a[i][j]=sum; 
    nbcode=imatrix(1,nvar,1,8);        } 
    ncodemax[1]=1;      big=0.0; 
    if (cptcovn > 0) tricode(Tvar,nbcode,imx);      for (i=j;i<=n;i++) { 
          sum=a[i][j]; 
    codtab=imatrix(1,100,1,10);        for (k=1;k<j;k++) 
    h=0;          sum -= a[i][k]*a[k][j]; 
    m=pow(2,cptcovn);        a[i][j]=sum; 
          if ( (dum=vv[i]*fabs(sum)) >= big) { 
    for(k=1;k<=cptcovn; k++){          big=dum; 
      for(i=1; i <=(m/pow(2,k));i++){          imax=i; 
        for(j=1; j <= ncodemax[k]; j++){        } 
          for(cpt=1; cpt <=(m/pow(2,cptcovn+1-k)); cpt++){      } 
            h++;      if (j != imax) { 
            if (h>m) h=1;codtab[h][k]=j;        for (k=1;k<=n;k++) { 
          }          dum=a[imax][k]; 
        }          a[imax][k]=a[j][k]; 
      }          a[j][k]=dum; 
    }        } 
         *d = -(*d); 
    /*for(i=1; i <=m ;i++){        vv[imax]=vv[j]; 
      for(k=1; k <=cptcovn; k++){      } 
        printf("i=%d k=%d %d ",i,k,codtab[i][k]);      indx[j]=imax; 
      }      if (a[j][j] == 0.0) a[j][j]=TINY; 
      printf("\n");      if (j != n) { 
    }*/        dum=1.0/(a[j][j]); 
    /*scanf("%d",i);*/        for (i=j+1;i<=n;i++) a[i][j] *= dum; 
          } 
    /* Calculates basic frequencies. Computes observed prevalence at single age    } 
        and prints on file fileres'p'. */    free_vector(vv,1,n);  /* Doesn't work */
   freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax);  ;
   } 
   
   /*scanf("%d ",i);*/  void lubksb(double **a, int n, int *indx, double b[]) 
   { 
     int i,ii=0,ip,j; 
     pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */    double sum; 
     oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */   
     newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */    for (i=1;i<=n;i++) { 
     savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */      ip=indx[i]; 
     oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */      sum=b[ip]; 
          b[ip]=b[i]; 
     /* For Powell, parameters are in a vector p[] starting at p[1]      if (ii) 
        so we point p on param[1][1] so that p[1] maps on param[1][1][1] */        for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
     p=param[1][1]; /* *(*(*(param +1)+1)+0) */      else if (sum) ii=i; 
          b[i]=sum; 
     mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);    } 
     for (i=n;i>=1;i--) { 
          sum=b[i]; 
     /*--------- results files --------------*/      for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
     fprintf(ficres,"\ntitle=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncov=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncov, nlstate, ndeath, maxwav, mle,weightopt,model);      b[i]=sum/a[i][i]; 
        } 
    jk=1;  } 
    fprintf(ficres,"# Parameters\n");  
    printf("# Parameters\n");  void pstamp(FILE *fichier)
    for(i=1,jk=1; i <=nlstate; i++){  {
      for(k=1; k <=(nlstate+ndeath); k++){    fprintf(fichier,"# %s.%s\n#%s\n#%s\n# %s", optionfilefiname,optionfilext,version,fullversion,strstart);
        if (k != i)  }
          {  
            printf("%d%d ",i,k);  /************ Frequencies ********************/
            fprintf(ficres,"%1d%1d ",i,k);  void  freqsummary(char fileres[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, int *Tvaraff, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[])
            for(j=1; j <=ncovmodel; j++){  {  /* Some frequencies */
              printf("%f ",p[jk]);    
              fprintf(ficres,"%f ",p[jk]);    int i, m, jk, k1,i1, j1, bool, z1,z2,j;
              jk++;    int first;
            }    double ***freq; /* Frequencies */
            printf("\n");    double *pp, **prop;
            fprintf(ficres,"\n");    double pos,posprop, k2, dateintsum=0,k2cpt=0;
          }    char fileresp[FILENAMELENGTH];
      }    
    }    pp=vector(1,nlstate);
     prop=matrix(1,nlstate,iagemin,iagemax+3);
     /* Computing hessian and covariance matrix */    strcpy(fileresp,"p");
     ftolhess=ftol; /* Usually correct */    strcat(fileresp,fileres);
     hesscov(matcov, p, npar, delti, ftolhess, func);    if((ficresp=fopen(fileresp,"w"))==NULL) {
     fprintf(ficres,"# Scales\n");      printf("Problem with prevalence resultfile: %s\n", fileresp);
     printf("# Scales\n");      fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
      for(i=1,jk=1; i <=nlstate; i++){      exit(0);
       for(j=1; j <=nlstate+ndeath; j++){    }
         if (j!=i) {    freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin,iagemax+3);
           fprintf(ficres,"%1d%1d",i,j);    j1=0;
           printf("%1d%1d",i,j);    
           for(k=1; k<=ncovmodel;k++){    j=cptcoveff;
             printf(" %.5e",delti[jk]);    if (cptcovn<1) {j=1;ncodemax[1]=1;}
             fprintf(ficres," %.5e",delti[jk]);  
             jk++;    first=1;
           }  
           printf("\n");    for(k1=1; k1<=j;k1++){
           fprintf(ficres,"\n");      for(i1=1; i1<=ncodemax[k1];i1++){
         }        j1++;
       }        /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
       }          scanf("%d", i);*/
            for (i=-5; i<=nlstate+ndeath; i++)  
     k=1;          for (jk=-5; jk<=nlstate+ndeath; jk++)  
     fprintf(ficres,"# Covariance\n");            for(m=iagemin; m <= iagemax+3; m++)
     printf("# Covariance\n");              freq[i][jk][m]=0;
     for(i=1;i<=npar;i++){  
       /*  if (k>nlstate) k=1;      for (i=1; i<=nlstate; i++)  
       i1=(i-1)/(ncovmodel*nlstate)+1;        for(m=iagemin; m <= iagemax+3; m++)
       fprintf(ficres,"%s%d%d",alph[k],i1,tab[i]);          prop[i][m]=0;
       printf("%s%d%d",alph[k],i1,tab[i]);*/        
       fprintf(ficres,"%3d",i);        dateintsum=0;
       printf("%3d",i);        k2cpt=0;
       for(j=1; j<=i;j++){        for (i=1; i<=imx; i++) {
         fprintf(ficres," %.5e",matcov[i][j]);          bool=1;
         printf(" %.5e",matcov[i][j]);          if  (cptcovn>0) {
       }            for (z1=1; z1<=cptcoveff; z1++) 
       fprintf(ficres,"\n");              if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtab[j1][z1]]) 
       printf("\n");                bool=0;
       k++;          }
     }          if (bool==1){
                for(m=firstpass; m<=lastpass; m++){
     while((c=getc(ficpar))=='#' && c!= EOF){              k2=anint[m][i]+(mint[m][i]/12.);
       ungetc(c,ficpar);              /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
       fgets(line, MAXLINE, ficpar);                if(agev[m][i]==0) agev[m][i]=iagemax+1;
       puts(line);                if(agev[m][i]==1) agev[m][i]=iagemax+2;
       fputs(line,ficparo);                if (s[m][i]>0 && s[m][i]<=nlstate) prop[s[m][i]][(int)agev[m][i]] += weight[i];
     }                if (m<lastpass) {
     ungetc(c,ficpar);                  freq[s[m][i]][s[m+1][i]][(int)agev[m][i]] += weight[i];
                    freq[s[m][i]][s[m+1][i]][iagemax+3] += weight[i];
     fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf\n",&agemin,&agemax, &bage, &fage);                }
                    
     if (fage <= 2) {                if ((agev[m][i]>1) && (agev[m][i]< (iagemax+3))) {
       bage = agemin;                  dateintsum=dateintsum+k2;
       fage = agemax;                  k2cpt++;
     }                }
                 /*}*/
     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");            }
     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f\n",agemin,agemax,bage,fage);          }
 /*------------ gnuplot -------------*/        }
 chdir(pathcd);         
   if((ficgp=fopen("graph.plt","w"))==NULL) {        /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
     printf("Problem with file graph.plt");goto end;        pstamp(ficresp);
   }        if  (cptcovn>0) {
 #ifdef windows          fprintf(ficresp, "\n#********** Variable "); 
   fprintf(ficgp,"cd \"%s\" \n",pathc);          for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
 #endif          fprintf(ficresp, "**********\n#");
 m=pow(2,cptcovn);        }
          for(i=1; i<=nlstate;i++) 
  /* 1eme*/          fprintf(ficresp, " Age Prev(%d) N(%d) N",i,i);
   for (cpt=1; cpt<= nlstate ; cpt ++) {        fprintf(ficresp, "\n");
    for (k1=1; k1<= m ; k1 ++) {        
         for(i=iagemin; i <= iagemax+3; i++){
 #ifdef windows          if(i==iagemax+3){
     fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter gif small size 400,300\nplot [%.f:%.f] \"vpl%s\" every :::%d::%d u 1:2 \"\%%lf",agemin,fage,fileres,k1-1,k1-1);            fprintf(ficlog,"Total");
 #endif          }else{
 #ifdef unix            if(first==1){
 fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nplot [%.f:%.f] \"vpl%s\" u 1:2 \"\%%lf",agemin,fage,fileres);              first=0;
 #endif              printf("See log file for details...\n");
             }
 for (i=1; i<= nlstate ; i ++) {            fprintf(ficlog,"Age %d", i);
   if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");          }
   else fprintf(ficgp," \%%*lf (\%%*lf)");          for(jk=1; jk <=nlstate ; jk++){
 }            for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
     fprintf(ficgp,"\" t\"Stationary prevalence\" w l 0,\"vpl%s\" every :::%d::%d u 1:($2+2*$3) \"\%%lf",fileres,k1-1,k1-1);              pp[jk] += freq[jk][m][i]; 
     for (i=1; i<= nlstate ; i ++) {          }
   if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");          for(jk=1; jk <=nlstate ; jk++){
   else fprintf(ficgp," \%%*lf (\%%*lf)");            for(m=-1, pos=0; m <=0 ; m++)
 }              pos += freq[jk][m][i];
   fprintf(ficgp,"\" t\"95\%% CI\" w l 1,\"vpl%s\" every :::%d::%d u 1:($2-2*$3) \"\%%lf",fileres,k1-1,k1-1);            if(pp[jk]>=1.e-10){
      for (i=1; i<= nlstate ; i ++) {              if(first==1){
   if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");              printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
   else fprintf(ficgp," \%%*lf (\%%*lf)");              }
 }                fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
      fprintf(ficgp,"\" t\"\" w l 1,\"p%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence \" w l 2",fileres,k1-1,k1-1,2+4*(cpt-1));            }else{
 #ifdef unix              if(first==1)
 fprintf(ficgp,"\nset ter gif small size 400,300");                printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
 #endif              fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
 fprintf(ficgp,"\nset out \"v%s%d%d.gif\" \nreplot\n\n",strtok(optionfile, "."),cpt,k1);            }
    }          }
   }  
   /*2 eme*/          for(jk=1; jk <=nlstate ; jk++){
             for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)
   for (k1=1; k1<= m ; k1 ++) {              pp[jk] += freq[jk][m][i];
     fprintf(ficgp,"set ylabel \"Years\" \nset ter gif small size 400,300\nplot [%.f:%.f] ",agemin,fage);          }       
              for(jk=1,pos=0,posprop=0; jk <=nlstate ; jk++){
     for (i=1; i<= nlstate+1 ; i ++) {            pos += pp[jk];
       k=2*i;            posprop += prop[jk][i];
       fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:2 \"\%%lf",fileres,k1-1,k1-1);          }
       for (j=1; j<= nlstate+1 ; j ++) {          for(jk=1; jk <=nlstate ; jk++){
   if (j==i) fprintf(ficgp," \%%lf (\%%lf)");            if(pos>=1.e-5){
   else fprintf(ficgp," \%%*lf (\%%*lf)");              if(first==1)
 }                  printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
       if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l ,");              fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
       else fprintf(ficgp,"\" t\"LE in state (%d)\" w l ,",i-1);            }else{
     fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:($2-$3*2) \"\%%lf",fileres,k1-1,k1-1);              if(first==1)
       for (j=1; j<= nlstate+1 ; j ++) {                printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
         if (j==i) fprintf(ficgp," \%%lf (\%%lf)");              fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
         else fprintf(ficgp," \%%*lf (\%%*lf)");            }
 }              if( i <= iagemax){
       fprintf(ficgp,"\" t\"\" w l 0,");              if(pos>=1.e-5){
      fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:($2+$3*2) \"\%%lf",fileres,k1-1,k1-1);                fprintf(ficresp," %d %.5f %.0f %.0f",i,prop[jk][i]/posprop, prop[jk][i],posprop);
       for (j=1; j<= nlstate+1 ; j ++) {                /*probs[i][jk][j1]= pp[jk]/pos;*/
   if (j==i) fprintf(ficgp," \%%lf (\%%lf)");                /*printf("\ni=%d jk=%d j1=%d %.5f %.0f %.0f %f",i,jk,j1,pp[jk]/pos, pp[jk],pos,probs[i][jk][j1]);*/
   else fprintf(ficgp," \%%*lf (\%%*lf)");              }
 }                else
       if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l 0");                fprintf(ficresp," %d NaNq %.0f %.0f",i,prop[jk][i],posprop);
       else fprintf(ficgp,"\" t\"\" w l 0,");            }
     }          }
     fprintf(ficgp,"\nset out \"e%s%d.gif\" \nreplot\n\n",strtok(optionfile, "."),k1);          
   }          for(jk=-1; jk <=nlstate+ndeath; jk++)
              for(m=-1; m <=nlstate+ndeath; m++)
   /*3eme*/              if(freq[jk][m][i] !=0 ) {
               if(first==1)
    for (k1=1; k1<= m ; k1 ++) {                printf(" %d%d=%.0f",jk,m,freq[jk][m][i]);
     for (cpt=1; cpt<= nlstate ; cpt ++) {                fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][i]);
       k=2+nlstate*(cpt-1);              }
       fprintf(ficgp,"set ter gif small size 400,300\nplot [%.f:%.f] \"e%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",agemin,fage,fileres,k1-1,k1-1,k,cpt);          if(i <= iagemax)
       for (i=1; i< nlstate ; i ++) {            fprintf(ficresp,"\n");
         fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",fileres,k1-1,k1-1,k+i,cpt,i+1);          if(first==1)
       }            printf("Others in log...\n");
       fprintf(ficgp,"\nset out \"exp%s%d%d.gif\" \nreplot\n\n",strtok(optionfile, "."),cpt,k1);          fprintf(ficlog,"\n");
     }        }
    }      }
      }
   /* CV preval stat */    dateintmean=dateintsum/k2cpt; 
     for (k1=1; k1<= m ; k1 ++) {   
     for (cpt=1; cpt<nlstate ; cpt ++) {    fclose(ficresp);
       k=3;    free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin, iagemax+3);
       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter gif small size 400,300\nplot [%.f:%.f] \"pij%s\" u ($1==%d ? ($3):1/0):($%d/($%d",agemin,agemax,fileres,k1,k+cpt+1,k+1);    free_vector(pp,1,nlstate);
       for (i=1; i< nlstate ; i ++)    free_matrix(prop,1,nlstate,iagemin, iagemax+3);
         fprintf(ficgp,"+$%d",k+i+1);    /* End of Freq */
       fprintf(ficgp,")) t\"prev(%d,%d)\" w l",cpt,cpt+1);  }
        
       l=3+(nlstate+ndeath)*cpt;  /************ Prevalence ********************/
       fprintf(ficgp,",\"pij%s\" u ($1==%d ? ($3):1/0):($%d/($%d",fileres,k1,l+cpt+1,l+1);  void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
       for (i=1; i< nlstate ; i ++) {  {  
         l=3+(nlstate+ndeath)*cpt;    /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
         fprintf(ficgp,"+$%d",l+i+1);       in each health status at the date of interview (if between dateprev1 and dateprev2).
       }       We still use firstpass and lastpass as another selection.
       fprintf(ficgp,")) t\"prev(%d,%d)\" w l\n",cpt+1,cpt+1);      */
       fprintf(ficgp,"set out \"p%s%d%d.gif\" \nreplot\n\n",strtok(optionfile, "."),cpt,k1);   
     }    int i, m, jk, k1, i1, j1, bool, z1,z2,j;
   }    double ***freq; /* Frequencies */
      double *pp, **prop;
   /* proba elementaires */    double pos,posprop; 
   for(i=1,jk=1; i <=nlstate; i++){    double  y2; /* in fractional years */
     for(k=1; k <=(nlstate+ndeath); k++){    int iagemin, iagemax;
       if (k != i) {  
         /*  fprintf(ficgp,"%1d%1d ",i,k);*/    iagemin= (int) agemin;
         for(j=1; j <=ncovmodel; j++){    iagemax= (int) agemax;
           fprintf(ficgp,"%s%1d%1d=%f ",alph[j],i,k,p[jk]);    /*pp=vector(1,nlstate);*/
           jk++;    prop=matrix(1,nlstate,iagemin,iagemax+3); 
           fprintf(ficgp,"\n");    /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
         }    j1=0;
       }    
     }    j=cptcoveff;
   }    if (cptcovn<1) {j=1;ncodemax[1]=1;}
   for(jk=1; jk <=m; jk++) {    
   fprintf(ficgp,"\nset ter gif small size 400,300\nset log y\nplot  [%.f:%.f] ",agemin,agemax);    for(k1=1; k1<=j;k1++){
   for(i=1; i <=nlstate; i++) {      for(i1=1; i1<=ncodemax[k1];i1++){
     for(k=1; k <=(nlstate+ndeath); k++){        j1++;
       if (k != i) {        
         fprintf(ficgp," exp(a%d%d+b%d%d*x",i,k,i,k);        for (i=1; i<=nlstate; i++)  
         for(j=3; j <=ncovmodel; j++)          for(m=iagemin; m <= iagemax+3; m++)
           fprintf(ficgp,"+%s%d%d*%d",alph[j],i,k,nbcode[Tvar[j-2]][codtab[jk][j-2]]);            prop[i][m]=0.0;
         fprintf(ficgp,")/(1");       
         for(k1=1; k1 <=(nlstate+ndeath); k1++)        for (i=1; i<=imx; i++) { /* Each individual */
           if (k1 != i) {          bool=1;
             fprintf(ficgp,"+exp(a%d%d+b%d%d*x",i,k1,i,k1);          if  (cptcovn>0) {
             for(j=3; j <=ncovmodel; j++)            for (z1=1; z1<=cptcoveff; z1++) 
               fprintf(ficgp,"+%s%d%d*%d",alph[j],i,k,nbcode[Tvar[j-2]][codtab[jk][j-2]]);              if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtab[j1][z1]]) 
             fprintf(ficgp,")");                bool=0;
           }          } 
         fprintf(ficgp,") t \"p%d%d\" ", i,k);          if (bool==1) { 
       if ((i+k)!= (nlstate*2+ndeath)) fprintf(ficgp,",");            for(m=firstpass; m<=lastpass; m++){/* Other selection (we can limit to certain interviews*/
       }              y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
     }              if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
   }                if(agev[m][i]==0) agev[m][i]=iagemax+1;
 fprintf(ficgp,"\nset out \"pe%s%d.gif\" \nreplot\n\n",strtok(optionfile, "."),jk);                  if(agev[m][i]==1) agev[m][i]=iagemax+2;
   }                if((int)agev[m][i] <iagemin || (int)agev[m][i] >iagemax+3) printf("Error on individual =%d agev[m][i]=%f m=%d\n",i, agev[m][i],m); 
                  if (s[m][i]>0 && s[m][i]<=nlstate) { 
  fclose(ficgp);                  /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   prop[s[m][i]][(int)agev[m][i]] += weight[i];
     chdir(path);                  prop[s[m][i]][iagemax+3] += weight[i]; 
     free_matrix(agev,1,maxwav,1,imx);                } 
     free_ivector(wav,1,imx);              }
     free_imatrix(dh,1,lastpass-firstpass+1,1,imx);            } /* end selection of waves */
     free_imatrix(mw,1,lastpass-firstpass+1,1,imx);          }
            }
     free_imatrix(s,1,maxwav+1,1,n);        for(i=iagemin; i <= iagemax+3; i++){  
              
              for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
     free_ivector(num,1,n);            posprop += prop[jk][i]; 
     free_vector(agedc,1,n);          } 
     free_vector(weight,1,n);  
     /*free_matrix(covar,1,NCOVMAX,1,n);*/          for(jk=1; jk <=nlstate ; jk++){     
     fclose(ficparo);            if( i <=  iagemax){ 
     fclose(ficres);              if(posprop>=1.e-5){ 
    }                probs[i][jk][j1]= prop[jk][i]/posprop;
                  } 
    /*________fin mle=1_________*/            } 
              }/* end jk */ 
         }/* end i */ 
        } /* end i1 */
     /* No more information from the sample is required now */    } /* end k1 */
   /* Reads comments: lines beginning with '#' */    
   while((c=getc(ficpar))=='#' && c!= EOF){    /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
     ungetc(c,ficpar);    /*free_vector(pp,1,nlstate);*/
     fgets(line, MAXLINE, ficpar);    free_matrix(prop,1,nlstate, iagemin,iagemax+3);
     puts(line);  }  /* End of prevalence */
     fputs(line,ficparo);  
   }  /************* Waves Concatenation ***************/
   ungetc(c,ficpar);  
    void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
   {
   fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf\n",&agemin,&agemax, &bage, &fage);    /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
   printf("agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f\n",agemin,agemax, bage, fage);       Death is a valid wave (if date is known).
   fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f\n",agemin,agemax,bage,fage);       mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
 /*--------- index.htm --------*/       dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
        and mw[mi+1][i]. dh depends on stepm.
   if((fichtm=fopen("index.htm","w"))==NULL)    {       */
     printf("Problem with index.htm \n");goto end;  
   }    int i, mi, m;
     /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
  fprintf(fichtm,"<body><ul> Imach, Version 0.63<hr> <li>Outputs files<br><br>\n       double sum=0., jmean=0.;*/
         - Observed prevalence in each state: <a href=\"p%s\">p%s</a> <br>\n    int first;
 - Estimated parameters and the covariance matrix: <a href=\"%s\">%s</a> <br>    int j, k=0,jk, ju, jl;
         - Stationary prevalence in each state: <a href=\"pl%s\">pl%s</a> <br>    double sum=0.;
         - Transition probabilities: <a href=\"pij%s\">pij%s</a><br>    first=0;
         - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>    jmin=1e+5;
         - Life expectancies by age and initial health status: <a href=\"e%s\">e%s</a> <br>    jmax=-1;
         - Variances of life expectancies by age and initial health status: <a href=\"v%s\">v%s</a><br>    jmean=0.;
         - Health expectancies with their variances: <a href=\"t%s\">t%s</a> <br>    for(i=1; i<=imx; i++){
         - Standard deviation of stationary prevalences: <a href=\"vpl%s\">vpl%s</a> <br><br>",fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres);      mi=0;
       m=firstpass;
  fprintf(fichtm," <li>Graphs</li>\n<p>");      while(s[m][i] <= nlstate){
         if(s[m][i]>=1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5)
  m=cptcovn;          mw[++mi][i]=m;
  if (cptcovn < 1) {m=1;ncodemax[1]=1;}        if(m >=lastpass)
           break;
  j1=0;        else
  for(k1=1; k1<=m;k1++){          m++;
    for(i1=1; i1<=ncodemax[k1];i1++){      }/* end while */
        j1++;      if (s[m][i] > nlstate){
        if (cptcovn > 0) {        mi++;     /* Death is another wave */
          fprintf(fichtm,"<hr>************ Results for covariates");        /* if(mi==0)  never been interviewed correctly before death */
          for (cpt=1; cpt<=cptcovn;cpt++)           /* Only death is a correct wave */
            fprintf(fichtm," V%d=%d ",Tvar[cpt],nbcode[Tvar[cpt]][codtab[j1][cpt]]);        mw[mi][i]=m;
          fprintf(fichtm," ************\n<hr>");      }
        }  
        fprintf(fichtm,"<br>- Probabilities: pe%s%d.gif<br>      wav[i]=mi;
 <img src=\"pe%s%d.gif\">",strtok(optionfile, "."),j1,strtok(optionfile, "."),j1);          if(mi==0){
        for(cpt=1; cpt<nlstate;cpt++){        nbwarn++;
          fprintf(fichtm,"<br>- Prevalence of disability : p%s%d%d.gif<br>        if(first==0){
 <img src=\"p%s%d%d.gif\">",strtok(optionfile, "."),cpt,j1,strtok(optionfile, "."),cpt,j1);          printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
        }          first=1;
     for(cpt=1; cpt<=nlstate;cpt++) {        }
        fprintf(fichtm,"<br>- Observed and stationary prevalence (with confident        if(first==1){
 interval) in state (%d): v%s%d%d.gif <br>          fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
 <img src=\"v%s%d%d.gif\">",cpt,strtok(optionfile, "."),cpt,j1,strtok(optionfile, "."),cpt,j1);          }
      }      } /* end mi==0 */
      for(cpt=1; cpt<=nlstate;cpt++) {    } /* End individuals */
         fprintf(fichtm,"\n<br>- Health life expectancies by age and initial health state (%d): exp%s%d%d.gif <br>  
 <img src=\"ex%s%d%d.gif\">",cpt,strtok(optionfile, "."),cpt,j1,strtok(optionfile, "."),cpt,j1);    for(i=1; i<=imx; i++){
      }      for(mi=1; mi<wav[i];mi++){
      fprintf(fichtm,"\n<br>- Total life expectancy by age and        if (stepm <=0)
 health expectancies in states (1) and (2): e%s%d.gif<br>          dh[mi][i]=1;
 <img src=\"e%s%d.gif\">",strtok(optionfile, "."),j1,strtok(optionfile, "."),j1);        else{
 fprintf(fichtm,"\n</body>");          if (s[mw[mi+1][i]][i] > nlstate) { /* A death */
    }            if (agedc[i] < 2*AGESUP) {
  }              j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
 fclose(fichtm);              if(j==0) j=1;  /* Survives at least one month after exam */
               else if(j<0){
   /*--------------- Prevalence limit --------------*/                nberr++;
                  printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
   strcpy(filerespl,"pl");                j=1; /* Temporary Dangerous patch */
   strcat(filerespl,fileres);                printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
   if((ficrespl=fopen(filerespl,"w"))==NULL) {                fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
     printf("Problem with Prev limit resultfile: %s\n", filerespl);goto end;                fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
   }              }
   printf("Computing prevalence limit: result on file '%s' \n", filerespl);              k=k+1;
   fprintf(ficrespl,"#Prevalence limit\n");              if (j >= jmax){
   fprintf(ficrespl,"#Age ");                jmax=j;
   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);                ijmax=i;
   fprintf(ficrespl,"\n");              }
                if (j <= jmin){
   prlim=matrix(1,nlstate,1,nlstate);                jmin=j;
   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */                ijmin=i;
   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */              }
   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */              sum=sum+j;
   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */              /*if (j<0) printf("j=%d num=%d \n",j,i);*/
   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */              /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
   k=0;            }
   agebase=agemin;          }
   agelim=agemax;          else{
   ftolpl=1.e-10;            j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
   i1=cptcovn;  /*        if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
   if (cptcovn < 1){i1=1;}  
             k=k+1;
   for(cptcov=1;cptcov<=i1;cptcov++){            if (j >= jmax) {
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){              jmax=j;
         k=k+1;              ijmax=i;
         /*printf("cptcov=%d cptcod=%d codtab=%d nbcode=%d\n",cptcov, cptcod,Tcode[cptcode],codtab[cptcod][cptcov]);*/            }
         fprintf(ficrespl,"\n#****** ");            else if (j <= jmin){
         for(j=1;j<=cptcovn;j++)              jmin=j;
           fprintf(ficrespl,"V%d=%d ",Tvar[j],nbcode[Tvar[j]][codtab[k][j]]);              ijmin=i;
         fprintf(ficrespl,"******\n");            }
                    /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
         for (age=agebase; age<=agelim; age++){            /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
           prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);            if(j<0){
           fprintf(ficrespl,"%.0f",age );              nberr++;
           for(i=1; i<=nlstate;i++)              printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
           fprintf(ficrespl," %.5f", prlim[i][i]);              fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
           fprintf(ficrespl,"\n");            }
         }            sum=sum+j;
       }          }
     }          jk= j/stepm;
   fclose(ficrespl);          jl= j -jk*stepm;
   /*------------- h Pij x at various ages ------------*/          ju= j -(jk+1)*stepm;
            if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
   strcpy(filerespij,"pij");  strcat(filerespij,fileres);            if(jl==0){
   if((ficrespij=fopen(filerespij,"w"))==NULL) {              dh[mi][i]=jk;
     printf("Problem with Pij resultfile: %s\n", filerespij);goto end;              bh[mi][i]=0;
   }            }else{ /* We want a negative bias in order to only have interpolation ie
   printf("Computing pij: result on file '%s' \n", filerespij);                    * at the price of an extra matrix product in likelihood */
                dh[mi][i]=jk+1;
   stepsize=(int) (stepm+YEARM-1)/YEARM;              bh[mi][i]=ju;
   if (stepm<=24) stepsize=2;            }
           }else{
   agelim=AGESUP;            if(jl <= -ju){
   hstepm=stepsize*YEARM; /* Every year of age */              dh[mi][i]=jk;
   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */              bh[mi][i]=jl;       /* bias is positive if real duration
                                     * is higher than the multiple of stepm and negative otherwise.
   k=0;                                   */
   for(cptcov=1;cptcov<=i1;cptcov++){            }
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){            else{
       k=k+1;              dh[mi][i]=jk+1;
         fprintf(ficrespij,"\n#****** ");              bh[mi][i]=ju;
         for(j=1;j<=cptcovn;j++)            }
           fprintf(ficrespij,"V%d=%d ",Tvar[j],nbcode[Tvar[j]][codtab[k][j]]);            if(dh[mi][i]==0){
         fprintf(ficrespij,"******\n");              dh[mi][i]=1; /* At least one step */
                      bh[mi][i]=ju; /* At least one step */
         for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */              /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
           nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */            }
           nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */          } /* end if mle */
           p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);        }
           oldm=oldms;savm=savms;      } /* end wave */
           hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);      }
           fprintf(ficrespij,"# Age");    jmean=sum/k;
           for(i=1; i<=nlstate;i++)    printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
             for(j=1; j<=nlstate+ndeath;j++)    fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
               fprintf(ficrespij," %1d-%1d",i,j);   }
           fprintf(ficrespij,"\n");  
           for (h=0; h<=nhstepm; h++){  /*********** Tricode ****************************/
             fprintf(ficrespij,"%d %.0f %.0f",k,agedeb, agedeb+ h*hstepm/YEARM*stepm );  void tricode(int *Tvar, int **nbcode, int imx)
             for(i=1; i<=nlstate;i++)  {
               for(j=1; j<=nlstate+ndeath;j++)    
                 fprintf(ficrespij," %.5f", p3mat[i][j][h]);    int Ndum[20],ij=1, k, j, i, maxncov=19;
             fprintf(ficrespij,"\n");    int cptcode=0;
           }    cptcoveff=0; 
           free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);   
           fprintf(ficrespij,"\n");    for (k=0; k<maxncov; k++) Ndum[k]=0;
         }    for (k=1; k<=7; k++) ncodemax[k]=0;
     }  
   }    for (j=1; j<=(cptcovn+2*cptcovprod); j++) {
       for (i=1; i<=imx; i++) { /*reads the data file to get the maximum 
   fclose(ficrespij);                                 modality*/ 
         ij=(int)(covar[Tvar[j]][i]); /* ij is the modality of this individual*/
   /*---------- Health expectancies and variances ------------*/        Ndum[ij]++; /*store the modality */
         /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
   strcpy(filerest,"t");        if (ij > cptcode) cptcode=ij; /* getting the maximum of covariable 
   strcat(filerest,fileres);                                         Tvar[j]. If V=sex and male is 0 and 
   if((ficrest=fopen(filerest,"w"))==NULL) {                                         female is 1, then  cptcode=1.*/
     printf("Problem with total LE resultfile: %s\n", filerest);goto end;      }
   }  
   printf("Computing Total LEs with variances: file '%s' \n", filerest);      for (i=0; i<=cptcode; i++) {
         if(Ndum[i]!=0) ncodemax[j]++; /* Nomber of modalities of the j th covariates. In fact ncodemax[j]=2 (dichotom. variables) but it can be more */
       }
   strcpy(filerese,"e");  
   strcat(filerese,fileres);      ij=1; 
   if((ficreseij=fopen(filerese,"w"))==NULL) {      for (i=1; i<=ncodemax[j]; i++) {
     printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);        for (k=0; k<= maxncov; k++) {
   }          if (Ndum[k] != 0) {
   printf("Computing Health Expectancies: result on file '%s' \n", filerese);            nbcode[Tvar[j]][ij]=k; 
             /* store the modality in an array. k is a modality. If we have model=V1+V1*sex then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
  strcpy(fileresv,"v");            
   strcat(fileresv,fileres);            ij++;
   if((ficresvij=fopen(fileresv,"w"))==NULL) {          }
     printf("Problem with variance resultfile: %s\n", fileresv);exit(0);          if (ij > ncodemax[j]) break; 
   }        }  
   printf("Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);      } 
     }  
   k=0;  
   for(cptcov=1;cptcov<=i1;cptcov++){   for (k=0; k< maxncov; k++) Ndum[k]=0;
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){  
       k=k+1;   for (i=1; i<=ncovmodel-2; i++) { 
       fprintf(ficrest,"\n#****** ");     /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/
       for(j=1;j<=cptcovn;j++)     ij=Tvar[i];
         fprintf(ficrest,"V%d=%d ",Tvar[j],nbcode[Tvar[j]][codtab[k][j]]);     Ndum[ij]++;
       fprintf(ficrest,"******\n");   }
   
       fprintf(ficreseij,"\n#****** ");   ij=1;
       for(j=1;j<=cptcovn;j++)   for (i=1; i<= maxncov; i++) {
         fprintf(ficreseij,"V%d=%d ",j,nbcode[j][codtab[k][j]]);     if((Ndum[i]!=0) && (i<=ncovcol)){
       fprintf(ficreseij,"******\n");       Tvaraff[ij]=i; /*For printing */
        ij++;
       fprintf(ficresvij,"\n#****** ");     }
       for(j=1;j<=cptcovn;j++)   }
         fprintf(ficresvij,"V%d=%d ",j,nbcode[j][codtab[k][j]]);   
       fprintf(ficresvij,"******\n");   cptcoveff=ij-1; /*Number of simple covariates*/
   }
       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);  
       oldm=oldms;savm=savms;  /*********** Health Expectancies ****************/
       evsij(fileres, eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k);    
       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);  void evsij(char fileres[], double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[] )
       oldm=oldms;savm=savms;  
       varevsij(fileres, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k);  {
          /* Health expectancies, no variances */
       fprintf(ficrest,"#Total LEs with variances: e.. (std) ");    int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2;
       for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);    double age, agelim, hf;
       fprintf(ficrest,"\n");    double ***p3mat;
            double eip;
       hf=1;  
       if (stepm >= YEARM) hf=stepm/YEARM;    pstamp(ficreseij);
       epj=vector(1,nlstate+1);    fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
       for(age=bage; age <=fage ;age++){    fprintf(ficreseij,"# Age");
         prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);    for(i=1; i<=nlstate;i++){
         fprintf(ficrest," %.0f",age);      for(j=1; j<=nlstate;j++){
         for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){        fprintf(ficreseij," e%1d%1d ",i,j);
           for(i=1, epj[j]=0.;i <=nlstate;i++) {      }
             epj[j] += prlim[i][i]*hf*eij[i][j][(int)age];      fprintf(ficreseij," e%1d. ",i);
           }    }
           epj[nlstate+1] +=epj[j];    fprintf(ficreseij,"\n");
         }  
         for(i=1, vepp=0.;i <=nlstate;i++)    
           for(j=1;j <=nlstate;j++)    if(estepm < stepm){
             vepp += vareij[i][j][(int)age];      printf ("Problem %d lower than %d\n",estepm, stepm);
         fprintf(ficrest," %.2f (%.2f)", epj[nlstate+1],hf*sqrt(vepp));    }
         for(j=1;j <=nlstate;j++){    else  hstepm=estepm;   
           fprintf(ficrest," %.2f (%.2f)", epj[j],hf*sqrt(vareij[j][j][(int)age]));    /* We compute the life expectancy from trapezoids spaced every estepm months
         }     * This is mainly to measure the difference between two models: for example
         fprintf(ficrest,"\n");     * if stepm=24 months pijx are given only every 2 years and by summing them
       }     * we are calculating an estimate of the Life Expectancy assuming a linear 
     }     * progression in between and thus overestimating or underestimating according
   }     * to the curvature of the survival function. If, for the same date, we 
             * estimate the model with stepm=1 month, we can keep estepm to 24 months
  fclose(ficreseij);     * to compare the new estimate of Life expectancy with the same linear 
  fclose(ficresvij);     * hypothesis. A more precise result, taking into account a more precise
   fclose(ficrest);     * curvature will be obtained if estepm is as small as stepm. */
   fclose(ficpar);  
   free_vector(epj,1,nlstate+1);    /* For example we decided to compute the life expectancy with the smallest unit */
   /*scanf("%d ",i); */    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
        nhstepm is the number of hstepm from age to agelim 
   /*------- Variance limit prevalence------*/         nstepm is the number of stepm from age to agelin. 
        Look at hpijx to understand the reason of that which relies in memory size
 strcpy(fileresvpl,"vpl");       and note for a fixed period like estepm months */
   strcat(fileresvpl,fileres);    /* We decided (b) to get a life expectancy respecting the most precise curvature of the
   if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {       survival function given by stepm (the optimization length). Unfortunately it
     printf("Problem with variance prev lim resultfile: %s\n", fileresvpl);       means that if the survival funtion is printed only each two years of age and if
     exit(0);       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
   }       results. So we changed our mind and took the option of the best precision.
   printf("Computing Variance-covariance of Prevalence limit: file '%s' \n", fileresvpl);    */
     hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
  k=0;  
  for(cptcov=1;cptcov<=i1;cptcov++){    agelim=AGESUP;
    for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){    /* nhstepm age range expressed in number of stepm */
      k=k+1;    nstepm=(int) rint((agelim-age)*YEARM/stepm); 
      fprintf(ficresvpl,"\n#****** ");    /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
      for(j=1;j<=cptcovn;j++)    /* if (stepm >= YEARM) hstepm=1;*/
        fprintf(ficresvpl,"V%d=%d ",Tvar[j],nbcode[Tvar[j]][codtab[k][j]]);    nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
      fprintf(ficresvpl,"******\n");    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
        
      varpl=matrix(1,nlstate,(int) bage, (int) fage);    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
      oldm=oldms;savm=savms;      /* Computed by stepm unit matrices, product of hstepm matrices, stored
      varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k);         in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
    }      
  }      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij);  
       
   fclose(ficresvpl);      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
       
   /*---------- End : free ----------------*/      printf("%d|",(int)age);fflush(stdout);
   free_matrix(varpl,1,nlstate,(int) bage, (int)fage);      fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
        
   free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);      /* Computing expectancies */
   free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);      for(i=1; i<=nlstate;i++)
          for(j=1; j<=nlstate;j++)
            for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
   free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);            eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);            
   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);            /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);  
            }
   free_matrix(matcov,1,npar,1,npar);  
   free_vector(delti,1,npar);      fprintf(ficreseij,"%3.0f",age );
        for(i=1; i<=nlstate;i++){
   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);        eip=0;
         for(j=1; j<=nlstate;j++){
   printf("End of Imach\n");          eip +=eij[i][j][(int)age];
   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */          fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
          }
   /* printf("Total time was %d Sec. %d uSec.\n", end_time.tv_sec -start_time.tv_sec, end_time.tv_usec -start_time.tv_usec);*/        fprintf(ficreseij,"%9.4f", eip );
   /*printf("Total time was %d uSec.\n", total_usecs);*/      }
   /*------ End -----------*/      fprintf(ficreseij,"\n");
       
  end:    }
 #ifdef windows    free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
  chdir(pathcd);    printf("\n");
 #endif    fprintf(ficlog,"\n");
  system("wgnuplot graph.plt");    
   }
 #ifdef windows  
   while (z[0] != 'q') {  void cvevsij(char fileres[], double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[] )
     chdir(pathcd);  
     printf("\nType e to edit output files, c to start again, and q for exiting: ");  {
     scanf("%s",z);    /* Covariances of health expectancies eij and of total life expectancies according
     if (z[0] == 'c') system("./imach");     to initial status i, ei. .
     else if (z[0] == 'e') {    */
       chdir(path);    int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
       system("index.htm");    double age, agelim, hf;
     }    double ***p3matp, ***p3matm, ***varhe;
     else if (z[0] == 'q') exit(0);    double **dnewm,**doldm;
   }    double *xp, *xm;
 #endif    double **gp, **gm;
 }    double ***gradg, ***trgradg;
     int theta;
   
     double eip, vip;
   
     varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
     xp=vector(1,npar);
     xm=vector(1,npar);
     dnewm=matrix(1,nlstate*nlstate,1,npar);
     doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
     
     pstamp(ficresstdeij);
     fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
     fprintf(ficresstdeij,"# Age");
     for(i=1; i<=nlstate;i++){
       for(j=1; j<=nlstate;j++)
         fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
       fprintf(ficresstdeij," e%1d. ",i);
     }
     fprintf(ficresstdeij,"\n");
   
     pstamp(ficrescveij);
     fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
     fprintf(ficrescveij,"# Age");
     for(i=1; i<=nlstate;i++)
       for(j=1; j<=nlstate;j++){
         cptj= (j-1)*nlstate+i;
         for(i2=1; i2<=nlstate;i2++)
           for(j2=1; j2<=nlstate;j2++){
             cptj2= (j2-1)*nlstate+i2;
             if(cptj2 <= cptj)
               fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
           }
       }
     fprintf(ficrescveij,"\n");
     
     if(estepm < stepm){
       printf ("Problem %d lower than %d\n",estepm, stepm);
     }
     else  hstepm=estepm;   
     /* We compute the life expectancy from trapezoids spaced every estepm months
      * This is mainly to measure the difference between two models: for example
      * if stepm=24 months pijx are given only every 2 years and by summing them
      * we are calculating an estimate of the Life Expectancy assuming a linear 
      * progression in between and thus overestimating or underestimating according
      * to the curvature of the survival function. If, for the same date, we 
      * estimate the model with stepm=1 month, we can keep estepm to 24 months
      * to compare the new estimate of Life expectancy with the same linear 
      * hypothesis. A more precise result, taking into account a more precise
      * curvature will be obtained if estepm is as small as stepm. */
   
     /* For example we decided to compute the life expectancy with the smallest unit */
     /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
        nhstepm is the number of hstepm from age to agelim 
        nstepm is the number of stepm from age to agelin. 
        Look at hpijx to understand the reason of that which relies in memory size
        and note for a fixed period like estepm months */
     /* We decided (b) to get a life expectancy respecting the most precise curvature of the
        survival function given by stepm (the optimization length). Unfortunately it
        means that if the survival funtion is printed only each two years of age and if
        you sum them up and add 1 year (area under the trapezoids) you won't get the same 
        results. So we changed our mind and took the option of the best precision.
     */
     hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
   
     /* If stepm=6 months */
     /* nhstepm age range expressed in number of stepm */
     agelim=AGESUP;
     nstepm=(int) rint((agelim-age)*YEARM/stepm); 
     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
     /* if (stepm >= YEARM) hstepm=1;*/
     nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
     
     p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
     trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
     gp=matrix(0,nhstepm,1,nlstate*nlstate);
     gm=matrix(0,nhstepm,1,nlstate*nlstate);
   
     for (age=bage; age<=fage; age ++){ 
   
       /* Computed by stepm unit matrices, product of hstepm matrices, stored
          in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
    
       hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
   
       /* Computing  Variances of health expectancies */
       /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
          decrease memory allocation */
       for(theta=1; theta <=npar; theta++){
         for(i=1; i<=npar; i++){ 
           xp[i] = x[i] + (i==theta ?delti[theta]:0);
           xm[i] = x[i] - (i==theta ?delti[theta]:0);
         }
         hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij);  
         hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij);  
     
         for(j=1; j<= nlstate; j++){
           for(i=1; i<=nlstate; i++){
             for(h=0; h<=nhstepm-1; h++){
               gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
               gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
             }
           }
         }
        
         for(ij=1; ij<= nlstate*nlstate; ij++)
           for(h=0; h<=nhstepm-1; h++){
             gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
           }
       }/* End theta */
       
       
       for(h=0; h<=nhstepm-1; h++)
         for(j=1; j<=nlstate*nlstate;j++)
           for(theta=1; theta <=npar; theta++)
             trgradg[h][j][theta]=gradg[h][theta][j];
       
   
        for(ij=1;ij<=nlstate*nlstate;ij++)
         for(ji=1;ji<=nlstate*nlstate;ji++)
           varhe[ij][ji][(int)age] =0.;
   
        printf("%d|",(int)age);fflush(stdout);
        fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
        for(h=0;h<=nhstepm-1;h++){
         for(k=0;k<=nhstepm-1;k++){
           matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
           matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
           for(ij=1;ij<=nlstate*nlstate;ij++)
             for(ji=1;ji<=nlstate*nlstate;ji++)
               varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
         }
       }
       /* Computing expectancies */
       hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij);  
       for(i=1; i<=nlstate;i++)
         for(j=1; j<=nlstate;j++)
           for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
             eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
             
             /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
   
           }
   
       fprintf(ficresstdeij,"%3.0f",age );
       for(i=1; i<=nlstate;i++){
         eip=0.;
         vip=0.;
         for(j=1; j<=nlstate;j++){
           eip += eij[i][j][(int)age];
           for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
             vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
           fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
         }
         fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
       }
       fprintf(ficresstdeij,"\n");
   
       fprintf(ficrescveij,"%3.0f",age );
       for(i=1; i<=nlstate;i++)
         for(j=1; j<=nlstate;j++){
           cptj= (j-1)*nlstate+i;
           for(i2=1; i2<=nlstate;i2++)
             for(j2=1; j2<=nlstate;j2++){
               cptj2= (j2-1)*nlstate+i2;
               if(cptj2 <= cptj)
                 fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
             }
         }
       fprintf(ficrescveij,"\n");
      
     }
     free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
     free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
     free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
     free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
     free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     printf("\n");
     fprintf(ficlog,"\n");
   
     free_vector(xm,1,npar);
     free_vector(xp,1,npar);
     free_matrix(dnewm,1,nlstate*nlstate,1,npar);
     free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
     free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
   }
   
   /************ Variance ******************/
   void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[])
   {
     /* Variance of health expectancies */
     /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
     /* double **newm;*/
     double **dnewm,**doldm;
     double **dnewmp,**doldmp;
     int i, j, nhstepm, hstepm, h, nstepm ;
     int k, cptcode;
     double *xp;
     double **gp, **gm;  /* for var eij */
     double ***gradg, ***trgradg; /*for var eij */
     double **gradgp, **trgradgp; /* for var p point j */
     double *gpp, *gmp; /* for var p point j */
     double **varppt; /* for var p point j nlstate to nlstate+ndeath */
     double ***p3mat;
     double age,agelim, hf;
     double ***mobaverage;
     int theta;
     char digit[4];
     char digitp[25];
   
     char fileresprobmorprev[FILENAMELENGTH];
   
     if(popbased==1){
       if(mobilav!=0)
         strcpy(digitp,"-populbased-mobilav-");
       else strcpy(digitp,"-populbased-nomobil-");
     }
     else 
       strcpy(digitp,"-stablbased-");
   
     if (mobilav!=0) {
       mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){
         fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
         printf(" Error in movingaverage mobilav=%d\n",mobilav);
       }
     }
   
     strcpy(fileresprobmorprev,"prmorprev"); 
     sprintf(digit,"%-d",ij);
     /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
     strcat(fileresprobmorprev,digit); /* Tvar to be done */
     strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
     strcat(fileresprobmorprev,fileres);
     if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
       printf("Problem with resultfile: %s\n", fileresprobmorprev);
       fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
     }
     printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
    
     fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
     pstamp(ficresprobmorprev);
     fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
     fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
     for(j=nlstate+1; j<=(nlstate+ndeath);j++){
       fprintf(ficresprobmorprev," p.%-d SE",j);
       for(i=1; i<=nlstate;i++)
         fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
     }  
     fprintf(ficresprobmorprev,"\n");
     fprintf(ficgp,"\n# Routine varevsij");
     /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
     fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
     fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
   /*   } */
     varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
     pstamp(ficresvij);
     fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
     if(popbased==1)
       fprintf(ficresvij,"the age specific prevalence observed in the population i.e cross-sectionally\n in each health state (popbased=1)");
     else
       fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
     fprintf(ficresvij,"# Age");
     for(i=1; i<=nlstate;i++)
       for(j=1; j<=nlstate;j++)
         fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
     fprintf(ficresvij,"\n");
   
     xp=vector(1,npar);
     dnewm=matrix(1,nlstate,1,npar);
     doldm=matrix(1,nlstate,1,nlstate);
     dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
     doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
   
     gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
     gpp=vector(nlstate+1,nlstate+ndeath);
     gmp=vector(nlstate+1,nlstate+ndeath);
     trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
     
     if(estepm < stepm){
       printf ("Problem %d lower than %d\n",estepm, stepm);
     }
     else  hstepm=estepm;   
     /* For example we decided to compute the life expectancy with the smallest unit */
     /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
        nhstepm is the number of hstepm from age to agelim 
        nstepm is the number of stepm from age to agelin. 
        Look at hpijx to understand the reason of that which relies in memory size
        and note for a fixed period like k years */
     /* We decided (b) to get a life expectancy respecting the most precise curvature of the
        survival function given by stepm (the optimization length). Unfortunately it
        means that if the survival funtion is printed every two years of age and if
        you sum them up and add 1 year (area under the trapezoids) you won't get the same 
        results. So we changed our mind and took the option of the best precision.
     */
     hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
     agelim = AGESUP;
     for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
       nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
       nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
       gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
       gp=matrix(0,nhstepm,1,nlstate);
       gm=matrix(0,nhstepm,1,nlstate);
   
   
       for(theta=1; theta <=npar; theta++){
         for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
           xp[i] = x[i] + (i==theta ?delti[theta]:0);
         }
         hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);  
         prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);
   
         if (popbased==1) {
           if(mobilav ==0){
             for(i=1; i<=nlstate;i++)
               prlim[i][i]=probs[(int)age][i][ij];
           }else{ /* mobilav */ 
             for(i=1; i<=nlstate;i++)
               prlim[i][i]=mobaverage[(int)age][i][ij];
           }
         }
     
         for(j=1; j<= nlstate; j++){
           for(h=0; h<=nhstepm; h++){
             for(i=1, gp[h][j]=0.;i<=nlstate;i++)
               gp[h][j] += prlim[i][i]*p3mat[i][j][h];
           }
         }
         /* This for computing probability of death (h=1 means
            computed over hstepm matrices product = hstepm*stepm months) 
            as a weighted average of prlim.
         */
         for(j=nlstate+1;j<=nlstate+ndeath;j++){
           for(i=1,gpp[j]=0.; i<= nlstate; i++)
             gpp[j] += prlim[i][i]*p3mat[i][j][1];
         }    
         /* end probability of death */
   
         for(i=1; i<=npar; i++) /* Computes gradient x - delta */
           xp[i] = x[i] - (i==theta ?delti[theta]:0);
         hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);  
         prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);
    
         if (popbased==1) {
           if(mobilav ==0){
             for(i=1; i<=nlstate;i++)
               prlim[i][i]=probs[(int)age][i][ij];
           }else{ /* mobilav */ 
             for(i=1; i<=nlstate;i++)
               prlim[i][i]=mobaverage[(int)age][i][ij];
           }
         }
   
         for(j=1; j<= nlstate; j++){
           for(h=0; h<=nhstepm; h++){
             for(i=1, gm[h][j]=0.;i<=nlstate;i++)
               gm[h][j] += prlim[i][i]*p3mat[i][j][h];
           }
         }
         /* This for computing probability of death (h=1 means
            computed over hstepm matrices product = hstepm*stepm months) 
            as a weighted average of prlim.
         */
         for(j=nlstate+1;j<=nlstate+ndeath;j++){
           for(i=1,gmp[j]=0.; i<= nlstate; i++)
            gmp[j] += prlim[i][i]*p3mat[i][j][1];
         }    
         /* end probability of death */
   
         for(j=1; j<= nlstate; j++) /* vareij */
           for(h=0; h<=nhstepm; h++){
             gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
           }
   
         for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
           gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
         }
   
       } /* End theta */
   
       trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
   
       for(h=0; h<=nhstepm; h++) /* veij */
         for(j=1; j<=nlstate;j++)
           for(theta=1; theta <=npar; theta++)
             trgradg[h][j][theta]=gradg[h][theta][j];
   
       for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
         for(theta=1; theta <=npar; theta++)
           trgradgp[j][theta]=gradgp[theta][j];
     
   
       hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
       for(i=1;i<=nlstate;i++)
         for(j=1;j<=nlstate;j++)
           vareij[i][j][(int)age] =0.;
   
       for(h=0;h<=nhstepm;h++){
         for(k=0;k<=nhstepm;k++){
           matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
           matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
           for(i=1;i<=nlstate;i++)
             for(j=1;j<=nlstate;j++)
               vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
         }
       }
     
       /* pptj */
       matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
       matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
       for(j=nlstate+1;j<=nlstate+ndeath;j++)
         for(i=nlstate+1;i<=nlstate+ndeath;i++)
           varppt[j][i]=doldmp[j][i];
       /* end ppptj */
       /*  x centered again */
       hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij);  
       prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ij);
    
       if (popbased==1) {
         if(mobilav ==0){
           for(i=1; i<=nlstate;i++)
             prlim[i][i]=probs[(int)age][i][ij];
         }else{ /* mobilav */ 
           for(i=1; i<=nlstate;i++)
             prlim[i][i]=mobaverage[(int)age][i][ij];
         }
       }
                
       /* This for computing probability of death (h=1 means
          computed over hstepm (estepm) matrices product = hstepm*stepm months) 
          as a weighted average of prlim.
       */
       for(j=nlstate+1;j<=nlstate+ndeath;j++){
         for(i=1,gmp[j]=0.;i<= nlstate; i++) 
           gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
       }    
       /* end probability of death */
   
       fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
       for(j=nlstate+1; j<=(nlstate+ndeath);j++){
         fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
         for(i=1; i<=nlstate;i++){
           fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
         }
       } 
       fprintf(ficresprobmorprev,"\n");
   
       fprintf(ficresvij,"%.0f ",age );
       for(i=1; i<=nlstate;i++)
         for(j=1; j<=nlstate;j++){
           fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
         }
       fprintf(ficresvij,"\n");
       free_matrix(gp,0,nhstepm,1,nlstate);
       free_matrix(gm,0,nhstepm,1,nlstate);
       free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
       free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     } /* End age */
     free_vector(gpp,nlstate+1,nlstate+ndeath);
     free_vector(gmp,nlstate+1,nlstate+ndeath);
     free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
     free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
     fprintf(ficgp,"\nset noparametric;set nolabel; set ter png small;set size 0.65, 0.65");
     /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
     fprintf(ficgp,"\n set log y; set nolog x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
   /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
   /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
   /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
     fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l 1 ",subdirf(fileresprobmorprev));
     fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95\%% interval\" w l 2 ",subdirf(fileresprobmorprev));
     fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l 2 ",subdirf(fileresprobmorprev));
     fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
     fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.png\"> <br>\n", estepm,subdirf3(optionfilefiname,"varmuptjgr",digitp),digit);
     /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.png\"> <br>\n", stepm,YEARM,digitp,digit);
   */
   /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.png\";replot;",digitp,optionfilefiname,digit); */
     fprintf(ficgp,"\nset out \"%s%s.png\";replot;\n",subdirf3(optionfilefiname,"varmuptjgr",digitp),digit);
   
     free_vector(xp,1,npar);
     free_matrix(doldm,1,nlstate,1,nlstate);
     free_matrix(dnewm,1,nlstate,1,npar);
     free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
     free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
     free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
     if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     fclose(ficresprobmorprev);
     fflush(ficgp);
     fflush(fichtm); 
   }  /* end varevsij */
   
   /************ Variance of prevlim ******************/
   void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij, char strstart[])
   {
     /* Variance of prevalence limit */
     /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
     double **newm;
     double **dnewm,**doldm;
     int i, j, nhstepm, hstepm;
     int k, cptcode;
     double *xp;
     double *gp, *gm;
     double **gradg, **trgradg;
     double age,agelim;
     int theta;
     
     pstamp(ficresvpl);
     fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
     fprintf(ficresvpl,"# Age");
     for(i=1; i<=nlstate;i++)
         fprintf(ficresvpl," %1d-%1d",i,i);
     fprintf(ficresvpl,"\n");
   
     xp=vector(1,npar);
     dnewm=matrix(1,nlstate,1,npar);
     doldm=matrix(1,nlstate,1,nlstate);
     
     hstepm=1*YEARM; /* Every year of age */
     hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
     agelim = AGESUP;
     for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
       nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
       if (stepm >= YEARM) hstepm=1;
       nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
       gradg=matrix(1,npar,1,nlstate);
       gp=vector(1,nlstate);
       gm=vector(1,nlstate);
   
       for(theta=1; theta <=npar; theta++){
         for(i=1; i<=npar; i++){ /* Computes gradient */
           xp[i] = x[i] + (i==theta ?delti[theta]:0);
         }
         prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);
         for(i=1;i<=nlstate;i++)
           gp[i] = prlim[i][i];
       
         for(i=1; i<=npar; i++) /* Computes gradient */
           xp[i] = x[i] - (i==theta ?delti[theta]:0);
         prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);
         for(i=1;i<=nlstate;i++)
           gm[i] = prlim[i][i];
   
         for(i=1;i<=nlstate;i++)
           gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
       } /* End theta */
   
       trgradg =matrix(1,nlstate,1,npar);
   
       for(j=1; j<=nlstate;j++)
         for(theta=1; theta <=npar; theta++)
           trgradg[j][theta]=gradg[theta][j];
   
       for(i=1;i<=nlstate;i++)
         varpl[i][(int)age] =0.;
       matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
       matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
       for(i=1;i<=nlstate;i++)
         varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
   
       fprintf(ficresvpl,"%.0f ",age );
       for(i=1; i<=nlstate;i++)
         fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
       fprintf(ficresvpl,"\n");
       free_vector(gp,1,nlstate);
       free_vector(gm,1,nlstate);
       free_matrix(gradg,1,npar,1,nlstate);
       free_matrix(trgradg,1,nlstate,1,npar);
     } /* End age */
   
     free_vector(xp,1,npar);
     free_matrix(doldm,1,nlstate,1,npar);
     free_matrix(dnewm,1,nlstate,1,nlstate);
   
   }
   
   /************ Variance of one-step probabilities  ******************/
   void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
   {
     int i, j=0,  i1, k1, l1, t, tj;
     int k2, l2, j1,  z1;
     int k=0,l, cptcode;
     int first=1, first1;
     double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
     double **dnewm,**doldm;
     double *xp;
     double *gp, *gm;
     double **gradg, **trgradg;
     double **mu;
     double age,agelim, cov[NCOVMAX];
     double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
     int theta;
     char fileresprob[FILENAMELENGTH];
     char fileresprobcov[FILENAMELENGTH];
     char fileresprobcor[FILENAMELENGTH];
   
     double ***varpij;
   
     strcpy(fileresprob,"prob"); 
     strcat(fileresprob,fileres);
     if((ficresprob=fopen(fileresprob,"w"))==NULL) {
       printf("Problem with resultfile: %s\n", fileresprob);
       fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
     }
     strcpy(fileresprobcov,"probcov"); 
     strcat(fileresprobcov,fileres);
     if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
       printf("Problem with resultfile: %s\n", fileresprobcov);
       fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
     }
     strcpy(fileresprobcor,"probcor"); 
     strcat(fileresprobcor,fileres);
     if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
       printf("Problem with resultfile: %s\n", fileresprobcor);
       fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
     }
     printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
     fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
     printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
     fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
     printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
     fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
     pstamp(ficresprob);
     fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
     fprintf(ficresprob,"# Age");
     pstamp(ficresprobcov);
     fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
     fprintf(ficresprobcov,"# Age");
     pstamp(ficresprobcor);
     fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
     fprintf(ficresprobcor,"# Age");
   
   
     for(i=1; i<=nlstate;i++)
       for(j=1; j<=(nlstate+ndeath);j++){
         fprintf(ficresprob," p%1d-%1d (SE)",i,j);
         fprintf(ficresprobcov," p%1d-%1d ",i,j);
         fprintf(ficresprobcor," p%1d-%1d ",i,j);
       }  
    /* fprintf(ficresprob,"\n");
     fprintf(ficresprobcov,"\n");
     fprintf(ficresprobcor,"\n");
    */
    xp=vector(1,npar);
     dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
     doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
     mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
     varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
     first=1;
     fprintf(ficgp,"\n# Routine varprob");
     fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
     fprintf(fichtm,"\n");
   
     fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of pairs of step probabilities (drawings)</a></h4></li>\n",optionfilehtmcov);
     fprintf(fichtmcov,"\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n\
     file %s<br>\n",optionfilehtmcov);
     fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated\
   and drawn. It helps understanding how is the covariance between two incidences.\
    They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
     fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
   It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
   would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
   standard deviations wide on each axis. <br>\
    Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
    and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
   To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
   
     cov[1]=1;
     tj=cptcoveff;
     if (cptcovn<1) {tj=1;ncodemax[1]=1;}
     j1=0;
     for(t=1; t<=tj;t++){
       for(i1=1; i1<=ncodemax[t];i1++){ 
         j1++;
         if  (cptcovn>0) {
           fprintf(ficresprob, "\n#********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
           fprintf(ficresprob, "**********\n#\n");
           fprintf(ficresprobcov, "\n#********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
           fprintf(ficresprobcov, "**********\n#\n");
           
           fprintf(ficgp, "\n#********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
           fprintf(ficgp, "**********\n#\n");
           
           
           fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
           fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
           
           fprintf(ficresprobcor, "\n#********** Variable ");    
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
           fprintf(ficresprobcor, "**********\n#");    
         }
         
         for (age=bage; age<=fage; age ++){ 
           cov[2]=age;
           for (k=1; k<=cptcovn;k++) {
             cov[2+k]=nbcode[Tvar[k]][codtab[j1][Tvar[k]]];
           }
           for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];
           for (k=1; k<=cptcovprod;k++)
             cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];
           
           gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
           trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
           gp=vector(1,(nlstate)*(nlstate+ndeath));
           gm=vector(1,(nlstate)*(nlstate+ndeath));
       
           for(theta=1; theta <=npar; theta++){
             for(i=1; i<=npar; i++)
               xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
             
             pmij(pmmij,cov,ncovmodel,xp,nlstate);
             
             k=0;
             for(i=1; i<= (nlstate); i++){
               for(j=1; j<=(nlstate+ndeath);j++){
                 k=k+1;
                 gp[k]=pmmij[i][j];
               }
             }
             
             for(i=1; i<=npar; i++)
               xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
       
             pmij(pmmij,cov,ncovmodel,xp,nlstate);
             k=0;
             for(i=1; i<=(nlstate); i++){
               for(j=1; j<=(nlstate+ndeath);j++){
                 k=k+1;
                 gm[k]=pmmij[i][j];
               }
             }
        
             for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
               gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
           }
   
           for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
             for(theta=1; theta <=npar; theta++)
               trgradg[j][theta]=gradg[theta][j];
           
           matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
           matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
           free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
           free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
           free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
           free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
   
           pmij(pmmij,cov,ncovmodel,x,nlstate);
           
           k=0;
           for(i=1; i<=(nlstate); i++){
             for(j=1; j<=(nlstate+ndeath);j++){
               k=k+1;
               mu[k][(int) age]=pmmij[i][j];
             }
           }
           for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
             for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
               varpij[i][j][(int)age] = doldm[i][j];
   
           /*printf("\n%d ",(int)age);
             for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
             printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
             fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
             }*/
   
           fprintf(ficresprob,"\n%d ",(int)age);
           fprintf(ficresprobcov,"\n%d ",(int)age);
           fprintf(ficresprobcor,"\n%d ",(int)age);
   
           for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
             fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
           for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
             fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
             fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
           }
           i=0;
           for (k=1; k<=(nlstate);k++){
             for (l=1; l<=(nlstate+ndeath);l++){ 
               i=i++;
               fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
               fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
               for (j=1; j<=i;j++){
                 fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                 fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
               }
             }
           }/* end of loop for state */
         } /* end of loop for age */
   
         /* Confidence intervalle of pij  */
         /*
           fprintf(ficgp,"\nset noparametric;unset label");
           fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
           fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
           fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
           fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
           fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
           fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
         */
   
         /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
         first1=1;
         for (k2=1; k2<=(nlstate);k2++){
           for (l2=1; l2<=(nlstate+ndeath);l2++){ 
             if(l2==k2) continue;
             j=(k2-1)*(nlstate+ndeath)+l2;
             for (k1=1; k1<=(nlstate);k1++){
               for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                 if(l1==k1) continue;
                 i=(k1-1)*(nlstate+ndeath)+l1;
                 if(i<=j) continue;
                 for (age=bage; age<=fage; age ++){ 
                   if ((int)age %5==0){
                     v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                     v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                     cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                     mu1=mu[i][(int) age]/stepm*YEARM ;
                     mu2=mu[j][(int) age]/stepm*YEARM;
                     c12=cv12/sqrt(v1*v2);
                     /* Computing eigen value of matrix of covariance */
                     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                     /* Eigen vectors */
                     v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                     /*v21=sqrt(1.-v11*v11); *//* error */
                     v21=(lc1-v1)/cv12*v11;
                     v12=-v21;
                     v22=v11;
                     tnalp=v21/v11;
                     if(first1==1){
                       first1=0;
                       printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                     }
                     fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                     /*printf(fignu*/
                     /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                     /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                     if(first==1){
                       first=0;
                       fprintf(ficgp,"\nset parametric;unset label");
                       fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                       fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                       fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
    :<a href=\"%s%d%1d%1d-%1d%1d.png\">\
   %s%d%1d%1d-%1d%1d.png</A>, ",k1,l1,k2,l2,\
                               subdirf2(optionfilefiname,"varpijgr"), j1,k1,l1,k2,l2,\
                               subdirf2(optionfilefiname,"varpijgr"), j1,k1,l1,k2,l2);
                       fprintf(fichtmcov,"\n<br><img src=\"%s%d%1d%1d-%1d%1d.png\"> ",subdirf2(optionfilefiname,"varpijgr"), j1,k1,l1,k2,l2);
                       fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                       fprintf(ficgp,"\nset out \"%s%d%1d%1d-%1d%1d.png\"",subdirf2(optionfilefiname,"varpijgr"), j1,k1,l1,k2,l2);
                       fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                       fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                       fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",\
                               mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),\
                               mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                     }else{
                       first=0;
                       fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                       fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                       fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                       fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",\
                               mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),\
                               mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                     }/* if first */
                   } /* age mod 5 */
                 } /* end loop age */
                 fprintf(ficgp,"\nset out \"%s%d%1d%1d-%1d%1d.png\";replot;",subdirf2(optionfilefiname,"varpijgr"), j1,k1,l1,k2,l2);
                 first=1;
               } /*l12 */
             } /* k12 */
           } /*l1 */
         }/* k1 */
       } /* loop covariates */
     }
     free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
     free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
     free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
     free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
     free_vector(xp,1,npar);
     fclose(ficresprob);
     fclose(ficresprobcov);
     fclose(ficresprobcor);
     fflush(ficgp);
     fflush(fichtmcov);
   }
   
   
   /******************* Printing html file ***********/
   void printinghtml(char fileres[], char title[], char datafile[], int firstpass, \
                     int lastpass, int stepm, int weightopt, char model[],\
                     int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
                     int popforecast, int estepm ,\
                     double jprev1, double mprev1,double anprev1, \
                     double jprev2, double mprev2,double anprev2){
     int jj1, k1, i1, cpt;
   
      fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
      <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
   </ul>");
      fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n \
    - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> <br>\n ",
              jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirf2(fileres,"p"),subdirf2(fileres,"p"));
      fprintf(fichtm,"\
    - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
              stepm,subdirf2(fileres,"pij"),subdirf2(fileres,"pij"));
      fprintf(fichtm,"\
    - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
              subdirf2(fileres,"pl"),subdirf2(fileres,"pl"));
      fprintf(fichtm,"\
    - (a) Life expectancies by health status at initial age, (b) health expectancies by health status at initial age:  ei., eij (estepm=%2d months): \
      <a href=\"%s\">%s</a> <br>\n</li>",
              estepm,subdirf2(fileres,"e"),subdirf2(fileres,"e"));
   
   
   fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
   
    m=cptcoveff;
    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
   
    jj1=0;
    for(k1=1; k1<=m;k1++){
      for(i1=1; i1<=ncodemax[k1];i1++){
        jj1++;
        if (cptcovn > 0) {
          fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
          for (cpt=1; cpt<=cptcoveff;cpt++) 
            fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtab[jj1][cpt]]);
          fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
        }
        /* Pij */
        fprintf(fichtm,"<br>- Pij or Conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s%d1.png\">%s%d1.png</a><br> \
   <img src=\"%s%d1.png\">",stepm,subdirf2(optionfilefiname,"pe"),jj1,subdirf2(optionfilefiname,"pe"),jj1,subdirf2(optionfilefiname,"pe"),jj1);     
        /* Quasi-incidences */
        fprintf(fichtm,"<br>- Pij or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
    before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too: <a href=\"%s%d2.png\">%s%d2.png</a><br> \
   <img src=\"%s%d2.png\">",stepm,subdirf2(optionfilefiname,"pe"),jj1,subdirf2(optionfilefiname,"pe"),jj1,subdirf2(optionfilefiname,"pe"),jj1); 
          /* Period (stable) prevalence in each health state */
          for(cpt=1; cpt<nlstate;cpt++){
            fprintf(fichtm,"<br>- Period (stable) prevalence in each health state : <a href=\"%s%d%d.png\">%s%d%d.png</a><br> \
   <img src=\"%s%d%d.png\">",subdirf2(optionfilefiname,"p"),cpt,jj1,subdirf2(optionfilefiname,"p"),cpt,jj1,subdirf2(optionfilefiname,"p"),cpt,jj1);
          }
        for(cpt=1; cpt<=nlstate;cpt++) {
           fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies : <a href=\"%s%d%d.png\">%s%d%d.png</a> <br> \
   <img src=\"%s%d%d.png\">",cpt,subdirf2(optionfilefiname,"exp"),cpt,jj1,subdirf2(optionfilefiname,"exp"),cpt,jj1,subdirf2(optionfilefiname,"exp"),cpt,jj1);
        }
      } /* end i1 */
    }/* End k1 */
    fprintf(fichtm,"</ul>");
   
   
    fprintf(fichtm,"\
   \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
    - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br>\n", rfileres,rfileres);
   
    fprintf(fichtm," - Variance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
            subdirf2(fileres,"prob"),subdirf2(fileres,"prob"));
    fprintf(fichtm,"\
    - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
            subdirf2(fileres,"probcov"),subdirf2(fileres,"probcov"));
   
    fprintf(fichtm,"\
    - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
            subdirf2(fileres,"probcor"),subdirf2(fileres,"probcor"));
    fprintf(fichtm,"\
    - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
      <a href=\"%s\">%s</a> <br>\n</li>",
              estepm,subdirf2(fileres,"cve"),subdirf2(fileres,"cve"));
    fprintf(fichtm,"\
    - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
      <a href=\"%s\">%s</a> <br>\n</li>",
              estepm,subdirf2(fileres,"stde"),subdirf2(fileres,"stde"));
    fprintf(fichtm,"\
    - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), eij are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences (i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
            estepm, subdirf2(fileres,"v"),subdirf2(fileres,"v"));
    fprintf(fichtm,"\
    - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors: <a href=\"%s\">%s</a> <br>\n",
            subdirf2(fileres,"t"),subdirf2(fileres,"t"));
    fprintf(fichtm,"\
    - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
            subdirf2(fileres,"vpl"),subdirf2(fileres,"vpl"));
   
   /*  if(popforecast==1) fprintf(fichtm,"\n */
   /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
   /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
   /*      <br>",fileres,fileres,fileres,fileres); */
   /*  else  */
   /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
    fflush(fichtm);
    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
   
    m=cptcoveff;
    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
   
    jj1=0;
    for(k1=1; k1<=m;k1++){
      for(i1=1; i1<=ncodemax[k1];i1++){
        jj1++;
        if (cptcovn > 0) {
          fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
          for (cpt=1; cpt<=cptcoveff;cpt++) 
            fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtab[jj1][cpt]]);
          fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
        }
        for(cpt=1; cpt<=nlstate;cpt++) {
          fprintf(fichtm,"<br>- Observed (cross-sectional) and period (incidence based) \
   prevalence (with 95%% confidence interval) in state (%d): %s%d%d.png <br>\
   <img src=\"%s%d%d.png\">",cpt,subdirf2(optionfilefiname,"v"),cpt,jj1,subdirf2(optionfilefiname,"v"),cpt,jj1);  
        }
        fprintf(fichtm,"\n<br>- Total life expectancy by age and \
   health expectancies in states (1) and (2): %s%d.png<br>\
   <img src=\"%s%d.png\">",subdirf2(optionfilefiname,"e"),jj1,subdirf2(optionfilefiname,"e"),jj1);
      } /* end i1 */
    }/* End k1 */
    fprintf(fichtm,"</ul>");
    fflush(fichtm);
   }
   
   /******************* Gnuplot file **************/
   void printinggnuplot(char fileres[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
   
     char dirfileres[132],optfileres[132];
     int m,cpt,k1,i,k,j,jk,k2,k3,ij,l;
     int ng;
   /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
   /*     printf("Problem with file %s",optionfilegnuplot); */
   /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
   /*   } */
   
     /*#ifdef windows */
     fprintf(ficgp,"cd \"%s\" \n",pathc);
       /*#endif */
     m=pow(2,cptcoveff);
   
     strcpy(dirfileres,optionfilefiname);
     strcpy(optfileres,"vpl");
    /* 1eme*/
     for (cpt=1; cpt<= nlstate ; cpt ++) {
      for (k1=1; k1<= m ; k1 ++) {
        fprintf(ficgp,"\nset out \"%s%d%d.png\" \n",subdirf2(optionfilefiname,"v"),cpt,k1);
        fprintf(ficgp,"\n#set out \"v%s%d%d.png\" \n",optionfilefiname,cpt,k1);
        fprintf(ficgp,"set xlabel \"Age\" \n\
   set ylabel \"Probability\" \n\
   set ter png small\n\
   set size 0.65,0.65\n\
   plot [%.f:%.f] \"%s\" every :::%d::%d u 1:2 \"\%%lf",ageminpar,fage,subdirf2(fileres,"vpl"),k1-1,k1-1);
   
        for (i=1; i<= nlstate ; i ++) {
          if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");
          else fprintf(ficgp," \%%*lf (\%%*lf)");
        }
        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l 0,\"%s\" every :::%d::%d u 1:($2+1.96*$3) \"\%%lf",subdirf2(fileres,"vpl"),k1-1,k1-1);
        for (i=1; i<= nlstate ; i ++) {
          if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");
          else fprintf(ficgp," \%%*lf (\%%*lf)");
        } 
        fprintf(ficgp,"\" t\"95\%% CI\" w l 1,\"%s\" every :::%d::%d u 1:($2-1.96*$3) \"\%%lf",subdirf2(fileres,"vpl"),k1-1,k1-1); 
        for (i=1; i<= nlstate ; i ++) {
          if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");
          else fprintf(ficgp," \%%*lf (\%%*lf)");
        }  
        fprintf(ficgp,"\" t\"\" w l 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence \" w l 2",subdirf2(fileres,"p"),k1-1,k1-1,2+4*(cpt-1));
      }
     }
     /*2 eme*/
     
     for (k1=1; k1<= m ; k1 ++) { 
       fprintf(ficgp,"\nset out \"%s%d.png\" \n",subdirf2(optionfilefiname,"e"),k1);
       fprintf(ficgp,"set ylabel \"Years\" \nset ter png small\nset size 0.65,0.65\nplot [%.f:%.f] ",ageminpar,fage);
       
       for (i=1; i<= nlstate+1 ; i ++) {
         k=2*i;
         fprintf(ficgp,"\"%s\" every :::%d::%d u 1:2 \"\%%lf",subdirf2(fileres,"t"),k1-1,k1-1);
         for (j=1; j<= nlstate+1 ; j ++) {
           if (j==i) fprintf(ficgp," \%%lf (\%%lf)");
           else fprintf(ficgp," \%%*lf (\%%*lf)");
         }   
         if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l ,");
         else fprintf(ficgp,"\" t\"LE in state (%d)\" w l ,",i-1);
         fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2-$3*2) \"\%%lf",subdirf2(fileres,"t"),k1-1,k1-1);
         for (j=1; j<= nlstate+1 ; j ++) {
           if (j==i) fprintf(ficgp," \%%lf (\%%lf)");
           else fprintf(ficgp," \%%*lf (\%%*lf)");
         }   
         fprintf(ficgp,"\" t\"\" w l 0,");
         fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2+$3*2) \"\%%lf",subdirf2(fileres,"t"),k1-1,k1-1);
         for (j=1; j<= nlstate+1 ; j ++) {
           if (j==i) fprintf(ficgp," \%%lf (\%%lf)");
           else fprintf(ficgp," \%%*lf (\%%*lf)");
         }   
         if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l 0");
         else fprintf(ficgp,"\" t\"\" w l 0,");
       }
     }
     
     /*3eme*/
     
     for (k1=1; k1<= m ; k1 ++) { 
       for (cpt=1; cpt<= nlstate ; cpt ++) {
         /*       k=2+nlstate*(2*cpt-2); */
         k=2+(nlstate+1)*(cpt-1);
         fprintf(ficgp,"\nset out \"%s%d%d.png\" \n",subdirf2(optionfilefiname,"exp"),cpt,k1);
         fprintf(ficgp,"set ter png small\n\
   set size 0.65,0.65\n\
   plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileres,"e"),k1-1,k1-1,k,cpt);
         /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
           for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
           fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
           fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
           for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
           fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
           
         */
         for (i=1; i< nlstate ; i ++) {
           fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+i,cpt,i+1);
           /*      fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
           
         } 
         fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+nlstate,cpt);
       }
     }
     
     /* CV preval stable (period) */
     for (k1=1; k1<= m ; k1 ++) { 
       for (cpt=1; cpt<=nlstate ; cpt ++) {
         k=3;
         fprintf(ficgp,"\nset out \"%s%d%d.png\" \n",subdirf2(optionfilefiname,"p"),cpt,k1);
         fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
   set ter png small\nset size 0.65,0.65\n\
   unset log y\n\
   plot [%.f:%.f] \"%s\" u ($1==%d ? ($3):1/0):($%d/($%d",ageminpar,agemaxpar,subdirf2(fileres,"pij"),k1,k+cpt+1,k+1);
         
         for (i=1; i< nlstate ; i ++)
           fprintf(ficgp,"+$%d",k+i+1);
         fprintf(ficgp,")) t\"prev(%d,%d)\" w l",cpt,cpt+1);
         
         l=3+(nlstate+ndeath)*cpt;
         fprintf(ficgp,",\"%s\" u ($1==%d ? ($3):1/0):($%d/($%d",subdirf2(fileres,"pij"),k1,l+cpt+1,l+1);
         for (i=1; i< nlstate ; i ++) {
           l=3+(nlstate+ndeath)*cpt;
           fprintf(ficgp,"+$%d",l+i+1);
         }
         fprintf(ficgp,")) t\"prev(%d,%d)\" w l\n",cpt+1,cpt+1);   
       } 
     }  
     
     /* proba elementaires */
     for(i=1,jk=1; i <=nlstate; i++){
       for(k=1; k <=(nlstate+ndeath); k++){
         if (k != i) {
           for(j=1; j <=ncovmodel; j++){
             fprintf(ficgp,"p%d=%f ",jk,p[jk]);
             jk++; 
             fprintf(ficgp,"\n");
           }
         }
       }
      }
   
      for(ng=1; ng<=2;ng++){ /* Number of graphics: first is probabilities second is incidence per year*/
        for(jk=1; jk <=m; jk++) {
          fprintf(ficgp,"\nset out \"%s%d%d.png\" \n",subdirf2(optionfilefiname,"pe"),jk,ng); 
          if (ng==2)
            fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
          else
            fprintf(ficgp,"\nset title \"Probability\"\n");
          fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65\nset log y\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
          i=1;
          for(k2=1; k2<=nlstate; k2++) {
            k3=i;
            for(k=1; k<=(nlstate+ndeath); k++) {
              if (k != k2){
                if(ng==2)
                  fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                else
                  fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                ij=1;
                for(j=3; j <=ncovmodel; j++) {
                  if(((j-2)==Tage[ij]) &&(ij <=cptcovage)) {
                    fprintf(ficgp,"+p%d*%d*x",i+j-1,nbcode[Tvar[j-2]][codtab[jk][Tvar[j-2]]]);
                    ij++;
                  }
                  else
                    fprintf(ficgp,"+p%d*%d",i+j-1,nbcode[Tvar[j-2]][codtab[jk][j-2]]);
                }
                fprintf(ficgp,")/(1");
                
                for(k1=1; k1 <=nlstate; k1++){   
                  fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                  ij=1;
                  for(j=3; j <=ncovmodel; j++){
                    if(((j-2)==Tage[ij]) &&(ij <=cptcovage)) {
                      fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2,nbcode[Tvar[j-2]][codtab[jk][Tvar[j-2]]]);
                      ij++;
                    }
                    else
                      fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2,nbcode[Tvar[j-2]][codtab[jk][j-2]]);
                  }
                  fprintf(ficgp,")");
                }
                fprintf(ficgp,") t \"p%d%d\" ", k2,k);
                if ((k+k2)!= (nlstate*2+ndeath)) fprintf(ficgp,",");
                i=i+ncovmodel;
              }
            } /* end k */
          } /* end k2 */
        } /* end jk */
      } /* end ng */
      fflush(ficgp); 
   }  /* end gnuplot */
   
   
   /*************** Moving average **************/
   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav){
   
     int i, cpt, cptcod;
     int modcovmax =1;
     int mobilavrange, mob;
     double age;
   
     modcovmax=2*cptcoveff;/* Max number of modalities. We suppose 
                              a covariate has 2 modalities */
     if (cptcovn<1) modcovmax=1; /* At least 1 pass */
   
     if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
       if(mobilav==1) mobilavrange=5; /* default */
       else mobilavrange=mobilav;
       for (age=bage; age<=fage; age++)
         for (i=1; i<=nlstate;i++)
           for (cptcod=1;cptcod<=modcovmax;cptcod++)
             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
       /* We keep the original values on the extreme ages bage, fage and for 
          fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
          we use a 5 terms etc. until the borders are no more concerned. 
       */ 
       for (mob=3;mob <=mobilavrange;mob=mob+2){
         for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
           for (i=1; i<=nlstate;i++){
             for (cptcod=1;cptcod<=modcovmax;cptcod++){
               mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                 for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                 }
               mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
             }
           }
         }/* end age */
       }/* end mob */
     }else return -1;
     return 0;
   }/* End movingaverage */
   
   
   /************** Forecasting ******************/
   prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
     /* proj1, year, month, day of starting projection 
        agemin, agemax range of age
        dateprev1 dateprev2 range of dates during which prevalence is computed
        anproj2 year of en of projection (same day and month as proj1).
     */
     int yearp, stepsize, hstepm, nhstepm, j, k, c, cptcod, i, h, i1;
     int *popage;
     double agec; /* generic age */
     double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
     double *popeffectif,*popcount;
     double ***p3mat;
     double ***mobaverage;
     char fileresf[FILENAMELENGTH];
   
     agelim=AGESUP;
     prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
    
     strcpy(fileresf,"f"); 
     strcat(fileresf,fileres);
     if((ficresf=fopen(fileresf,"w"))==NULL) {
       printf("Problem with forecast resultfile: %s\n", fileresf);
       fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
     }
     printf("Computing forecasting: result on file '%s' \n", fileresf);
     fprintf(ficlog,"Computing forecasting: result on file '%s' \n", fileresf);
   
     if (cptcoveff==0) ncodemax[cptcoveff]=1;
   
     if (mobilav!=0) {
       mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){
         fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
         printf(" Error in movingaverage mobilav=%d\n",mobilav);
       }
     }
   
     stepsize=(int) (stepm+YEARM-1)/YEARM;
     if (stepm<=12) stepsize=1;
     if(estepm < stepm){
       printf ("Problem %d lower than %d\n",estepm, stepm);
     }
     else  hstepm=estepm;   
   
     hstepm=hstepm/stepm; 
     yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                                  fractional in yp1 */
     anprojmean=yp;
     yp2=modf((yp1*12),&yp);
     mprojmean=yp;
     yp1=modf((yp2*30.5),&yp);
     jprojmean=yp;
     if(jprojmean==0) jprojmean=1;
     if(mprojmean==0) jprojmean=1;
   
     i1=cptcoveff;
     if (cptcovn < 1){i1=1;}
     
     fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
     
     fprintf(ficresf,"#****** Routine prevforecast **\n");
   
   /*            if (h==(int)(YEARM*yearp)){ */
     for(cptcov=1, k=0;cptcov<=i1;cptcov++){
       for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){
         k=k+1;
         fprintf(ficresf,"\n#******");
         for(j=1;j<=cptcoveff;j++) {
           fprintf(ficresf," V%d=%d, hpijx=probability over h years, hp.jx is weighted by observed prev ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
         }
         fprintf(ficresf,"******\n");
         fprintf(ficresf,"# Covariate valuofcovar yearproj age");
         for(j=1; j<=nlstate+ndeath;j++){ 
           for(i=1; i<=nlstate;i++)              
             fprintf(ficresf," p%d%d",i,j);
           fprintf(ficresf," p.%d",j);
         }
         for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) { 
           fprintf(ficresf,"\n");
           fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
   
           for (agec=fage; agec>=(ageminpar-1); agec--){ 
             nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
             nhstepm = nhstepm/hstepm; 
             p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             oldm=oldms;savm=savms;
             hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k);  
           
             for (h=0; h<=nhstepm; h++){
               if (h*hstepm/YEARM*stepm ==yearp) {
                 fprintf(ficresf,"\n");
                 for(j=1;j<=cptcoveff;j++) 
                   fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
                 fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
               } 
               for(j=1; j<=nlstate+ndeath;j++) {
                 ppij=0.;
                 for(i=1; i<=nlstate;i++) {
                   if (mobilav==1) 
                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod];
                   else {
                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod];
                   }
                   if (h*hstepm/YEARM*stepm== yearp) {
                     fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   }
                 } /* end i */
                 if (h*hstepm/YEARM*stepm==yearp) {
                   fprintf(ficresf," %.3f", ppij);
                 }
               }/* end j */
             } /* end h */
             free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           } /* end agec */
         } /* end yearp */
       } /* end cptcod */
     } /* end  cptcov */
          
     if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
   
     fclose(ficresf);
   }
   
   /************** Forecasting *****not tested NB*************/
   populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){
     
     int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h;
     int *popage;
     double calagedatem, agelim, kk1, kk2;
     double *popeffectif,*popcount;
     double ***p3mat,***tabpop,***tabpopprev;
     double ***mobaverage;
     char filerespop[FILENAMELENGTH];
   
     tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     agelim=AGESUP;
     calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM;
     
     prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
     
     
     strcpy(filerespop,"pop"); 
     strcat(filerespop,fileres);
     if((ficrespop=fopen(filerespop,"w"))==NULL) {
       printf("Problem with forecast resultfile: %s\n", filerespop);
       fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop);
     }
     printf("Computing forecasting: result on file '%s' \n", filerespop);
     fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop);
   
     if (cptcoveff==0) ncodemax[cptcoveff]=1;
   
     if (mobilav!=0) {
       mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){
         fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
         printf(" Error in movingaverage mobilav=%d\n",mobilav);
       }
     }
   
     stepsize=(int) (stepm+YEARM-1)/YEARM;
     if (stepm<=12) stepsize=1;
     
     agelim=AGESUP;
     
     hstepm=1;
     hstepm=hstepm/stepm; 
     
     if (popforecast==1) {
       if((ficpop=fopen(popfile,"r"))==NULL) {
         printf("Problem with population file : %s\n",popfile);exit(0);
         fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0);
       } 
       popage=ivector(0,AGESUP);
       popeffectif=vector(0,AGESUP);
       popcount=vector(0,AGESUP);
       
       i=1;   
       while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1;
      
       imx=i;
       for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i];
     }
   
     for(cptcov=1,k=0;cptcov<=i2;cptcov++){
      for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){
         k=k+1;
         fprintf(ficrespop,"\n#******");
         for(j=1;j<=cptcoveff;j++) {
           fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
         }
         fprintf(ficrespop,"******\n");
         fprintf(ficrespop,"# Age");
         for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j);
         if (popforecast==1)  fprintf(ficrespop," [Population]");
         
         for (cpt=0; cpt<=0;cpt++) { 
           fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);   
           
           for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){ 
             nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); 
             nhstepm = nhstepm/hstepm; 
             
             p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             oldm=oldms;savm=savms;
             hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
           
             for (h=0; h<=nhstepm; h++){
               if (h==(int) (calagedatem+YEARM*cpt)) {
                 fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm);
               } 
               for(j=1; j<=nlstate+ndeath;j++) {
                 kk1=0.;kk2=0;
                 for(i=1; i<=nlstate;i++) {              
                   if (mobilav==1) 
                     kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod];
                   else {
                     kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod];
                   }
                 }
                 if (h==(int)(calagedatem+12*cpt)){
                   tabpop[(int)(agedeb)][j][cptcod]=kk1;
                     /*fprintf(ficrespop," %.3f", kk1);
                       if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*/
                 }
               }
               for(i=1; i<=nlstate;i++){
                 kk1=0.;
                   for(j=1; j<=nlstate;j++){
                     kk1= kk1+tabpop[(int)(agedeb)][j][cptcod]; 
                   }
                     tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)];
               }
   
               if (h==(int)(calagedatem+12*cpt)) for(j=1; j<=nlstate;j++) 
                 fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]);
             }
             free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           }
         }
    
     /******/
   
         for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) { 
           fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);   
           for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){ 
             nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); 
             nhstepm = nhstepm/hstepm; 
             
             p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             oldm=oldms;savm=savms;
             hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
             for (h=0; h<=nhstepm; h++){
               if (h==(int) (calagedatem+YEARM*cpt)) {
                 fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm);
               } 
               for(j=1; j<=nlstate+ndeath;j++) {
                 kk1=0.;kk2=0;
                 for(i=1; i<=nlstate;i++) {              
                   kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];    
                 }
                 if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);        
               }
             }
             free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           }
         }
      } 
     }
    
     if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
   
     if (popforecast==1) {
       free_ivector(popage,0,AGESUP);
       free_vector(popeffectif,0,AGESUP);
       free_vector(popcount,0,AGESUP);
     }
     free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     fclose(ficrespop);
   } /* End of popforecast */
   
   int fileappend(FILE *fichier, char *optionfich)
   {
     if((fichier=fopen(optionfich,"a"))==NULL) {
       printf("Problem with file: %s\n", optionfich);
       fprintf(ficlog,"Problem with file: %s\n", optionfich);
       return (0);
     }
     fflush(fichier);
     return (1);
   }
   
   
   /**************** function prwizard **********************/
   void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
   {
   
     /* Wizard to print covariance matrix template */
   
     char ca[32], cb[32], cc[32];
     int i,j, k, l, li, lj, lk, ll, jj, npar, itimes;
     int numlinepar;
   
     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
     fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
     for(i=1; i <=nlstate; i++){
       jj=0;
       for(j=1; j <=nlstate+ndeath; j++){
         if(j==i) continue;
         jj++;
         /*ca[0]= k+'a'-1;ca[1]='\0';*/
         printf("%1d%1d",i,j);
         fprintf(ficparo,"%1d%1d",i,j);
         for(k=1; k<=ncovmodel;k++){
           /*        printf(" %lf",param[i][j][k]); */
           /*        fprintf(ficparo," %lf",param[i][j][k]); */
           printf(" 0.");
           fprintf(ficparo," 0.");
         }
         printf("\n");
         fprintf(ficparo,"\n");
       }
     }
     printf("# Scales (for hessian or gradient estimation)\n");
     fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
     npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
     for(i=1; i <=nlstate; i++){
       jj=0;
       for(j=1; j <=nlstate+ndeath; j++){
         if(j==i) continue;
         jj++;
         fprintf(ficparo,"%1d%1d",i,j);
         printf("%1d%1d",i,j);
         fflush(stdout);
         for(k=1; k<=ncovmodel;k++){
           /*      printf(" %le",delti3[i][j][k]); */
           /*      fprintf(ficparo," %le",delti3[i][j][k]); */
           printf(" 0.");
           fprintf(ficparo," 0.");
         }
         numlinepar++;
         printf("\n");
         fprintf(ficparo,"\n");
       }
     }
     printf("# Covariance matrix\n");
   /* # 121 Var(a12)\n\ */
   /* # 122 Cov(b12,a12) Var(b12)\n\ */
   /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
   /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
   /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
   /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
   /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
   /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
     fflush(stdout);
     fprintf(ficparo,"# Covariance matrix\n");
     /* # 121 Var(a12)\n\ */
     /* # 122 Cov(b12,a12) Var(b12)\n\ */
     /* #   ...\n\ */
     /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
     
     for(itimes=1;itimes<=2;itimes++){
       jj=0;
       for(i=1; i <=nlstate; i++){
         for(j=1; j <=nlstate+ndeath; j++){
           if(j==i) continue;
           for(k=1; k<=ncovmodel;k++){
             jj++;
             ca[0]= k+'a'-1;ca[1]='\0';
             if(itimes==1){
               printf("#%1d%1d%d",i,j,k);
               fprintf(ficparo,"#%1d%1d%d",i,j,k);
             }else{
               printf("%1d%1d%d",i,j,k);
               fprintf(ficparo,"%1d%1d%d",i,j,k);
               /*  printf(" %.5le",matcov[i][j]); */
             }
             ll=0;
             for(li=1;li <=nlstate; li++){
               for(lj=1;lj <=nlstate+ndeath; lj++){
                 if(lj==li) continue;
                 for(lk=1;lk<=ncovmodel;lk++){
                   ll++;
                   if(ll<=jj){
                     cb[0]= lk +'a'-1;cb[1]='\0';
                     if(ll<jj){
                       if(itimes==1){
                         printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                         fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                       }else{
                         printf(" 0.");
                         fprintf(ficparo," 0.");
                       }
                     }else{
                       if(itimes==1){
                         printf(" Var(%s%1d%1d)",ca,i,j);
                         fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                       }else{
                         printf(" 0.");
                         fprintf(ficparo," 0.");
                       }
                     }
                   }
                 } /* end lk */
               } /* end lj */
             } /* end li */
             printf("\n");
             fprintf(ficparo,"\n");
             numlinepar++;
           } /* end k*/
         } /*end j */
       } /* end i */
     } /* end itimes */
   
   } /* end of prwizard */
   /******************* Gompertz Likelihood ******************************/
   double gompertz(double x[])
   { 
     double A,B,L=0.0,sump=0.,num=0.;
     int i,n=0; /* n is the size of the sample */
   
     for (i=0;i<=imx-1 ; i++) {
       sump=sump+weight[i];
       /*    sump=sump+1;*/
       num=num+1;
     }
    
    
     /* for (i=0; i<=imx; i++) 
        if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
   
     for (i=1;i<=imx ; i++)
       {
         if (cens[i] == 1 && wav[i]>1)
           A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
         
         if (cens[i] == 0 && wav[i]>1)
           A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
         
         /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
         if (wav[i] > 1 ) { /* ??? */
           L=L+A*weight[i];
           /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
         }
       }
   
    /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
    
     return -2*L*num/sump;
   }
   
   /******************* Printing html file ***********/
   void printinghtmlmort(char fileres[], char title[], char datafile[], int firstpass, \
                     int lastpass, int stepm, int weightopt, char model[],\
                     int imx,  double p[],double **matcov,double agemortsup){
     int i,k;
   
     fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
     fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
     for (i=1;i<=2;i++) 
       fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
     fprintf(fichtm,"<br><br><img src=\"graphmort.png\">");
     fprintf(fichtm,"</ul>");
   
   fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
   
    fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
   
    for (k=agegomp;k<(agemortsup-2);k++) 
      fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
   
    
     fflush(fichtm);
   }
   
   /******************* Gnuplot file **************/
   void printinggnuplotmort(char fileres[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
   
     char dirfileres[132],optfileres[132];
     int m,cpt,k1,i,k,j,jk,k2,k3,ij,l;
     int ng;
   
   
     /*#ifdef windows */
     fprintf(ficgp,"cd \"%s\" \n",pathc);
       /*#endif */
   
   
     strcpy(dirfileres,optionfilefiname);
     strcpy(optfileres,"vpl");
     fprintf(ficgp,"set out \"graphmort.png\"\n "); 
     fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
     fprintf(ficgp, "set ter png small\n set log y\n"); 
     fprintf(ficgp, "set size 0.65,0.65\n");
     fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
   
   } 
   
   
   
   
   
   /***********************************************/
   /**************** Main Program *****************/
   /***********************************************/
   
   int main(int argc, char *argv[])
   {
     int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
     int i,j, k, n=MAXN,iter,m,size=100,cptcode, cptcod;
     int linei, month, year,iout;
     int jj, ll, li, lj, lk, imk;
     int numlinepar=0; /* Current linenumber of parameter file */
     int itimes;
     int NDIM=2;
   
     char ca[32], cb[32], cc[32];
     char dummy[]="                         ";
     /*  FILE *fichtm; *//* Html File */
     /* FILE *ficgp;*/ /*Gnuplot File */
     struct stat info;
     double agedeb, agefin,hf;
     double ageminpar=1.e20,agemin=1.e20, agemaxpar=-1.e20, agemax=-1.e20;
   
     double fret;
     double **xi,tmp,delta;
   
     double dum; /* Dummy variable */
     double ***p3mat;
     double ***mobaverage;
     int *indx;
     char line[MAXLINE], linepar[MAXLINE];
     char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE],model[MAXLINE];
     char pathr[MAXLINE], pathimach[MAXLINE]; 
     char **bp, *tok, *val; /* pathtot */
     int firstobs=1, lastobs=10;
     int sdeb, sfin; /* Status at beginning and end */
     int c,  h , cpt,l;
     int ju,jl, mi;
     int i1,j1, k1,k2,k3,jk,aa,bb, stepsize, ij;
     int jnais,jdc,jint4,jint1,jint2,jint3,**outcome,*tab; 
     int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
     int mobilav=0,popforecast=0;
     int hstepm, nhstepm;
     int agemortsup;
     float  sumlpop=0.;
     double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
     double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
   
     double bage, fage, age, agelim, agebase;
     double ftolpl=FTOL;
     double **prlim;
     double *severity;
     double ***param; /* Matrix of parameters */
     double  *p;
     double **matcov; /* Matrix of covariance */
     double ***delti3; /* Scale */
     double *delti; /* Scale */
     double ***eij, ***vareij;
     double **varpl; /* Variances of prevalence limits by age */
     double *epj, vepp;
     double kk1, kk2;
     double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
     double **ximort;
     char *alph[]={"a","a","b","c","d","e"}, str[4];
     int *dcwave;
   
     char z[1]="c", occ;
   
     char stra[80], strb[80], strc[80], strd[80],stre[80],modelsav[80];
     char  *strt, strtend[80];
     char *stratrunc;
     int lstra;
   
     long total_usecs;
    
   /*   setlocale (LC_ALL, ""); */
   /*   bindtextdomain (PACKAGE, LOCALEDIR); */
   /*   textdomain (PACKAGE); */
   /*   setlocale (LC_CTYPE, ""); */
   /*   setlocale (LC_MESSAGES, ""); */
   
     /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
     (void) gettimeofday(&start_time,&tzp);
     curr_time=start_time;
     tm = *localtime(&start_time.tv_sec);
     tmg = *gmtime(&start_time.tv_sec);
     strcpy(strstart,asctime(&tm));
   
   /*  printf("Localtime (at start)=%s",strstart); */
   /*  tp.tv_sec = tp.tv_sec +86400; */
   /*  tm = *localtime(&start_time.tv_sec); */
   /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
   /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
   /*   tmg.tm_hour=tmg.tm_hour + 1; */
   /*   tp.tv_sec = mktime(&tmg); */
   /*   strt=asctime(&tmg); */
   /*   printf("Time(after) =%s",strstart);  */
   /*  (void) time (&time_value);
   *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
   *  tm = *localtime(&time_value);
   *  strstart=asctime(&tm);
   *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
   */
   
     nberr=0; /* Number of errors and warnings */
     nbwarn=0;
     getcwd(pathcd, size);
   
     printf("\n%s\n%s",version,fullversion);
     if(argc <=1){
       printf("\nEnter the parameter file name: ");
       fgets(pathr,FILENAMELENGTH,stdin);
       i=strlen(pathr);
       if(pathr[i-1]=='\n')
         pathr[i-1]='\0';
      for (tok = pathr; tok != NULL; ){
         printf("Pathr |%s|\n",pathr);
         while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
         printf("val= |%s| pathr=%s\n",val,pathr);
         strcpy (pathtot, val);
         if(pathr[0] == '\0') break; /* Dirty */
       }
     }
     else{
       strcpy(pathtot,argv[1]);
     }
     /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
     /*cygwin_split_path(pathtot,path,optionfile);
       printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
     /* cutv(path,optionfile,pathtot,'\\');*/
   
     /* Split argv[0], imach program to get pathimach */
     printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
     split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
     printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
    /*   strcpy(pathimach,argv[0]); */
     /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
     split(pathtot,path,optionfile,optionfilext,optionfilefiname);
     printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
     chdir(path); /* Can be a relative path */
     if(getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
       printf("Current directory %s!\n",pathcd);
     strcpy(command,"mkdir ");
     strcat(command,optionfilefiname);
     if((outcmd=system(command)) != 0){
       printf("Problem creating directory or it already exists %s%s, err=%d\n",path,optionfilefiname,outcmd);
       /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
       /* fclose(ficlog); */
   /*     exit(1); */
     }
   /*   if((imk=mkdir(optionfilefiname))<0){ */
   /*     perror("mkdir"); */
   /*   } */
   
     /*-------- arguments in the command line --------*/
   
     /* Log file */
     strcat(filelog, optionfilefiname);
     strcat(filelog,".log");    /* */
     if((ficlog=fopen(filelog,"w"))==NULL)    {
       printf("Problem with logfile %s\n",filelog);
       goto end;
     }
     fprintf(ficlog,"Log filename:%s\n",filelog);
     fprintf(ficlog,"\n%s\n%s",version,fullversion);
     fprintf(ficlog,"\nEnter the parameter file name: \n");
     fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
    path=%s \n\
    optionfile=%s\n\
    optionfilext=%s\n\
    optionfilefiname=%s\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
   
     printf("Local time (at start):%s",strstart);
     fprintf(ficlog,"Local time (at start): %s",strstart);
     fflush(ficlog);
   /*   (void) gettimeofday(&curr_time,&tzp); */
   /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tv_sec-start_time.tv_sec,tmpout)); */
   
     /* */
     strcpy(fileres,"r");
     strcat(fileres, optionfilefiname);
     strcat(fileres,".txt");    /* Other files have txt extension */
   
     /*---------arguments file --------*/
   
     if((ficpar=fopen(optionfile,"r"))==NULL)    {
       printf("Problem with optionfile %s\n",optionfile);
       fprintf(ficlog,"Problem with optionfile %s\n",optionfile);
       fflush(ficlog);
       goto end;
     }
   
   
   
     strcpy(filereso,"o");
     strcat(filereso,fileres);
     if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
       printf("Problem with Output resultfile: %s\n", filereso);
       fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
       fflush(ficlog);
       goto end;
     }
   
     /* Reads comments: lines beginning with '#' */
     numlinepar=0;
     while((c=getc(ficpar))=='#' && c!= EOF){
       ungetc(c,ficpar);
       fgets(line, MAXLINE, ficpar);
       numlinepar++;
       puts(line);
       fputs(line,ficparo);
       fputs(line,ficlog);
     }
     ungetc(c,ficpar);
   
     fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model);
     numlinepar++;
     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model);
     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model);
     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model);
     fflush(ficlog);
     while((c=getc(ficpar))=='#' && c!= EOF){
       ungetc(c,ficpar);
       fgets(line, MAXLINE, ficpar);
       numlinepar++;
       puts(line);
       fputs(line,ficparo);
       fputs(line,ficlog);
     }
     ungetc(c,ficpar);
   
      
     covar=matrix(0,NCOVMAX,1,n); 
     cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement*/
     if (strlen(model)>1) cptcovn=nbocc(model,'+')+1;
   
     ncovmodel=2+cptcovn; /*Number of variables = cptcovn + intercept + age */
     nvar=ncovmodel-1; /* Suppressing age as a basic covariate */
     npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/
   
     delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
     delti=delti3[1][1];
     /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
     if(mle==-1){ /* Print a wizard for help writing covariance matrix */
       prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
       printf(" You choose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
       fprintf(ficlog," You choose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
       free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
       fclose (ficparo);
       fclose (ficlog);
       exit(0);
     }
     else if(mle==-3) {
       prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
       printf(" You choose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
       fprintf(ficlog," You choose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
       param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
       matcov=matrix(1,npar,1,npar);
     }
     else{
       /* Read guess parameters */
       /* Reads comments: lines beginning with '#' */
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         numlinepar++;
         puts(line);
         fputs(line,ficparo);
         fputs(line,ficlog);
       }
       ungetc(c,ficpar);
       
       param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
       for(i=1; i <=nlstate; i++){
         j=0;
         for(jj=1; jj <=nlstate+ndeath; jj++){
           if(jj==i) continue;
           j++;
           fscanf(ficpar,"%1d%1d",&i1,&j1);
           if ((i1 != i) && (j1 != j)){
             printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
             exit(1);
           }
           fprintf(ficparo,"%1d%1d",i1,j1);
           if(mle==1)
             printf("%1d%1d",i,j);
           fprintf(ficlog,"%1d%1d",i,j);
           for(k=1; k<=ncovmodel;k++){
             fscanf(ficpar," %lf",&param[i][j][k]);
             if(mle==1){
               printf(" %lf",param[i][j][k]);
               fprintf(ficlog," %lf",param[i][j][k]);
             }
             else
               fprintf(ficlog," %lf",param[i][j][k]);
             fprintf(ficparo," %lf",param[i][j][k]);
           }
           fscanf(ficpar,"\n");
           numlinepar++;
           if(mle==1)
             printf("\n");
           fprintf(ficlog,"\n");
           fprintf(ficparo,"\n");
         }
       }  
       fflush(ficlog);
   
       p=param[1][1];
       
       /* Reads comments: lines beginning with '#' */
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         numlinepar++;
         puts(line);
         fputs(line,ficparo);
         fputs(line,ficlog);
       }
       ungetc(c,ficpar);
   
       for(i=1; i <=nlstate; i++){
         for(j=1; j <=nlstate+ndeath-1; j++){
           fscanf(ficpar,"%1d%1d",&i1,&j1);
           if ((i1-i)*(j1-j)!=0){
             printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
             exit(1);
           }
           printf("%1d%1d",i,j);
           fprintf(ficparo,"%1d%1d",i1,j1);
           fprintf(ficlog,"%1d%1d",i1,j1);
           for(k=1; k<=ncovmodel;k++){
             fscanf(ficpar,"%le",&delti3[i][j][k]);
             printf(" %le",delti3[i][j][k]);
             fprintf(ficparo," %le",delti3[i][j][k]);
             fprintf(ficlog," %le",delti3[i][j][k]);
           }
           fscanf(ficpar,"\n");
           numlinepar++;
           printf("\n");
           fprintf(ficparo,"\n");
           fprintf(ficlog,"\n");
         }
       }
       fflush(ficlog);
   
       delti=delti3[1][1];
   
   
       /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
     
       /* Reads comments: lines beginning with '#' */
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         numlinepar++;
         puts(line);
         fputs(line,ficparo);
         fputs(line,ficlog);
       }
       ungetc(c,ficpar);
     
       matcov=matrix(1,npar,1,npar);
       for(i=1; i <=npar; i++){
         fscanf(ficpar,"%s",&str);
         if(mle==1)
           printf("%s",str);
         fprintf(ficlog,"%s",str);
         fprintf(ficparo,"%s",str);
         for(j=1; j <=i; j++){
           fscanf(ficpar," %le",&matcov[i][j]);
           if(mle==1){
             printf(" %.5le",matcov[i][j]);
           }
           fprintf(ficlog," %.5le",matcov[i][j]);
           fprintf(ficparo," %.5le",matcov[i][j]);
         }
         fscanf(ficpar,"\n");
         numlinepar++;
         if(mle==1)
           printf("\n");
         fprintf(ficlog,"\n");
         fprintf(ficparo,"\n");
       }
       for(i=1; i <=npar; i++)
         for(j=i+1;j<=npar;j++)
           matcov[i][j]=matcov[j][i];
       
       if(mle==1)
         printf("\n");
       fprintf(ficlog,"\n");
       
       fflush(ficlog);
       
       /*-------- Rewriting parameter file ----------*/
       strcpy(rfileres,"r");    /* "Rparameterfile */
       strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
       strcat(rfileres,".");    /* */
       strcat(rfileres,optionfilext);    /* Other files have txt extension */
       if((ficres =fopen(rfileres,"w"))==NULL) {
         printf("Problem writing new parameter file: %s\n", fileres);goto end;
         fprintf(ficlog,"Problem writing new parameter file: %s\n", fileres);goto end;
       }
       fprintf(ficres,"#%s\n",version);
     }    /* End of mle != -3 */
   
     /*-------- data file ----------*/
     if((fic=fopen(datafile,"r"))==NULL)    {
       printf("Problem while opening datafile: %s\n", datafile);goto end;
       fprintf(ficlog,"Problem while opening datafile: %s\n", datafile);goto end;
     }
   
     n= lastobs;
     severity = vector(1,maxwav);
     outcome=imatrix(1,maxwav+1,1,n);
     num=lvector(1,n);
     moisnais=vector(1,n);
     annais=vector(1,n);
     moisdc=vector(1,n);
     andc=vector(1,n);
     agedc=vector(1,n);
     cod=ivector(1,n);
     weight=vector(1,n);
     for(i=1;i<=n;i++) weight[i]=1.0; /* Equal weights, 1 by default */
     mint=matrix(1,maxwav,1,n);
     anint=matrix(1,maxwav,1,n);
     s=imatrix(1,maxwav+1,1,n);
     tab=ivector(1,NCOVMAX);
     ncodemax=ivector(1,8);
   
     i=1;
     linei=0;
     while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
       linei=linei+1;
       for(j=strlen(line); j>=0;j--){  /* Untabifies line */
         if(line[j] == '\t')
           line[j] = ' ';
       }
       for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
         ;
       };
       line[j+1]=0;  /* Trims blanks at end of line */
       if(line[0]=='#'){
         fprintf(ficlog,"Comment line\n%s\n",line);
         printf("Comment line\n%s\n",line);
         continue;
       }
   
       for (j=maxwav;j>=1;j--){
         cutv(stra, strb,line,' '); 
         errno=0;
         lval=strtol(strb,&endptr,10); 
         /*        if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
         if( strb[0]=='\0' || (*endptr != '\0')){
           printf("Error reading data around '%d' at line number %d %s for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
           exit(1);
         }
         s[j][i]=lval;
         
         strcpy(line,stra);
         cutv(stra, strb,line,' ');
         if(iout=sscanf(strb,"%d/%d",&month, &year) != 0){
         }
         else  if(iout=sscanf(strb,"%s.") != 0){
           month=99;
           year=9999;
         }else{
           printf("Error reading data around '%s' at line number %ld %s for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
           exit(1);
         }
         anint[j][i]= (double) year; 
         mint[j][i]= (double)month; 
         strcpy(line,stra);
       } /* ENd Waves */
       
       cutv(stra, strb,line,' '); 
       if(iout=sscanf(strb,"%d/%d",&month, &year) != 0){
       }
       else  if(iout=sscanf(strb,"%s.",dummy) != 0){
         month=99;
         year=9999;
       }else{
         printf("Error reading data around '%s' at line number %ld %s for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
         exit(1);
       }
       andc[i]=(double) year; 
       moisdc[i]=(double) month; 
       strcpy(line,stra);
       
       cutv(stra, strb,line,' '); 
       if(iout=sscanf(strb,"%d/%d",&month, &year) != 0){
       }
       else  if(iout=sscanf(strb,"%s.") != 0){
         month=99;
         year=9999;
       }else{
         printf("Error reading data around '%s' at line number %ld %s for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line,j);
         exit(1);
       }
       annais[i]=(double)(year);
       moisnais[i]=(double)(month); 
       strcpy(line,stra);
       
       cutv(stra, strb,line,' '); 
       errno=0;
       lval=strtol(strb,&endptr,10); 
       if( strb[0]=='\0' || (*endptr != '\0')){
         printf("Error reading data around '%d' at line number %ld %s for individual %d\nShould be a weight.  Exiting.\n",lval, i,line,linei);
         exit(1);
       }
       weight[i]=(double)(lval); 
       strcpy(line,stra);
       
       for (j=ncovcol;j>=1;j--){
         cutv(stra, strb,line,' '); 
         errno=0;
         lval=strtol(strb,&endptr,10); 
         if( strb[0]=='\0' || (*endptr != '\0')){
           printf("Error reading data around '%d' at line number %ld %s for individual %d, '%s'\nShould be a covar (meaning 0 for the reference or 1).  Exiting.\n",lval, linei,i, line);
           exit(1);
         }
         if(lval <-1 || lval >1){
           printf("Error reading data around '%d' at line number %ld %s for individual %d, '%s'\nShould be a value of the %d covar (meaning 0 for the reference or 1. IMaCh does not build design variables, do it your self).  Exiting.\n",lval,linei, i,line,j);
           exit(1);
         }
         covar[j][i]=(double)(lval);
         strcpy(line,stra);
       } 
       lstra=strlen(stra);
       
       if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
         stratrunc = &(stra[lstra-9]);
         num[i]=atol(stratrunc);
       }
       else
         num[i]=atol(stra);
       /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
         printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
       
       i=i+1;
     } /* End loop reading  data */
     fclose(fic);
     /* printf("ii=%d", ij);
        scanf("%d",i);*/
     imx=i-1; /* Number of individuals */
   
     /* for (i=1; i<=imx; i++){
       if ((s[1][i]==3) && (s[2][i]==2)) s[2][i]=3;
       if ((s[2][i]==3) && (s[3][i]==2)) s[3][i]=3;
       if ((s[3][i]==3) && (s[4][i]==2)) s[4][i]=3;
       }*/
      /*  for (i=1; i<=imx; i++){
        if (s[4][i]==9)  s[4][i]=-1; 
        printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]), (weight[i]), (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i]));}*/
     
     /* for (i=1; i<=imx; i++) */
    
      /*if ((s[3][i]==3) ||  (s[4][i]==3)) weight[i]=0.08;
        else weight[i]=1;*/
   
     /* Calculation of the number of parameters from char model */
     Tvar=ivector(1,15); /* stores the number n of the covariates in Vm+Vn at 1 and m at 2 */
     Tprod=ivector(1,15); 
     Tvaraff=ivector(1,15); 
     Tvard=imatrix(1,15,1,2);
     Tage=ivector(1,15);      
      
     if (strlen(model) >1){ /* If there is at least 1 covariate */
       j=0, j1=0, k1=1, k2=1;
       j=nbocc(model,'+'); /* j=Number of '+' */
       j1=nbocc(model,'*'); /* j1=Number of '*' */
       cptcovn=j+1; 
       cptcovprod=j1; /*Number of products */
       
       strcpy(modelsav,model); 
       if ((strcmp(model,"age")==0) || (strcmp(model,"age*age")==0)){
         printf("Error. Non available option model=%s ",model);
         fprintf(ficlog,"Error. Non available option model=%s ",model);
         goto end;
       }
       
       /* This loop fills the array Tvar from the string 'model'.*/
   
       for(i=(j+1); i>=1;i--){
         cutv(stra,strb,modelsav,'+'); /* keeps in strb after the last + */ 
         if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
         /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
         /*scanf("%d",i);*/
         if (strchr(strb,'*')) {  /* Model includes a product */
           cutv(strd,strc,strb,'*'); /* strd*strc  Vm*Vn (if not *age)*/
           if (strcmp(strc,"age")==0) { /* Vn*age */
             cptcovprod--;
             cutv(strb,stre,strd,'V');
             Tvar[i]=atoi(stre); /* computes n in Vn and stores in Tvar*/
             cptcovage++;
               Tage[cptcovage]=i;
               /*printf("stre=%s ", stre);*/
           }
           else if (strcmp(strd,"age")==0) { /* or age*Vn */
             cptcovprod--;
             cutv(strb,stre,strc,'V');
             Tvar[i]=atoi(stre);
             cptcovage++;
             Tage[cptcovage]=i;
           }
           else {  /* Age is not in the model */
             cutv(strb,stre,strc,'V'); /* strc= Vn, stre is n*/
             Tvar[i]=ncovcol+k1;
             cutv(strb,strc,strd,'V'); /* strd was Vm, strc is m */
             Tprod[k1]=i;
             Tvard[k1][1]=atoi(strc); /* m*/
             Tvard[k1][2]=atoi(stre); /* n */
             Tvar[cptcovn+k2]=Tvard[k1][1];
             Tvar[cptcovn+k2+1]=Tvard[k1][2]; 
             for (k=1; k<=lastobs;k++) 
               covar[ncovcol+k1][k]=covar[atoi(stre)][k]*covar[atoi(strc)][k];
             k1++;
             k2=k2+2;
           }
         }
         else { /* no more sum */
           /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
          /*  scanf("%d",i);*/
         cutv(strd,strc,strb,'V');
         Tvar[i]=atoi(strc);
         }
         strcpy(modelsav,stra);  
         /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
           scanf("%d",i);*/
       } /* end of loop + */
     } /* end model */
     
     /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
       If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
   
     /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
     printf("cptcovprod=%d ", cptcovprod);
     fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
   
     scanf("%d ",i);*/
   
       /*  if(mle==1){*/
     if (weightopt != 1) { /* Maximisation without weights*/
       for(i=1;i<=n;i++) weight[i]=1.0;
     }
       /*-calculation of age at interview from date of interview and age at death -*/
     agev=matrix(1,maxwav,1,imx);
   
     for (i=1; i<=imx; i++) {
       for(m=2; (m<= maxwav); m++) {
         if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
           anint[m][i]=9999;
           s[m][i]=-1;
         }
         if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
           nberr++;
           printf("Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results are biased\n",(int)moisdc[i],(int)andc[i],num[i],i);
           fprintf(ficlog,"Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results are biased\n",(int)moisdc[i],(int)andc[i],num[i],i);
           s[m][i]=-1;
         }
         if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
           nberr++;
           printf("Error! Month of death of individual %ld on line %d was unknown %2d, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,(int)moisdc[i]); 
           fprintf(ficlog,"Error! Month of death of individual %ld on line %d was unknown %f, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,moisdc[i]); 
           s[m][i]=-1; /* We prefer to skip it (and to skip it in version 0.8a1 too */
         }
       }
     }
   
     for (i=1; i<=imx; i++)  {
       agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
       for(m=firstpass; (m<= lastpass); m++){
         if(s[m][i] >0 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){
           if (s[m][i] >= nlstate+1) {
             if(agedc[i]>0)
               if((int)moisdc[i]!=99 && (int)andc[i]!=9999)
                 agev[m][i]=agedc[i];
             /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
               else {
                 if ((int)andc[i]!=9999){
                   nbwarn++;
                   printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   agev[m][i]=-1;
                 }
               }
           }
           else if(s[m][i] !=9){ /* Standard case, age in fractional
                                    years but with the precision of a month */
             agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
             if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
               agev[m][i]=1;
             else if(agev[m][i] <agemin){ 
               agemin=agev[m][i];
               /*printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], agemin);*/
             }
             else if(agev[m][i] >agemax){
               agemax=agev[m][i];
               /* printf(" anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.0f\n",m,i,anint[m][i], i,annais[i], agemax);*/
             }
             /*agev[m][i]=anint[m][i]-annais[i];*/
             /*     agev[m][i] = age[i]+2*m;*/
           }
           else { /* =9 */
             agev[m][i]=1;
             s[m][i]=-1;
           }
         }
         else /*= 0 Unknown */
           agev[m][i]=1;
       }
       
     }
     for (i=1; i<=imx; i++)  {
       for(m=firstpass; (m<=lastpass); m++){
         if (s[m][i] > (nlstate+ndeath)) {
           nberr++;
           printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
           fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
           goto end;
         }
       }
     }
   
     /*for (i=1; i<=imx; i++){
     for (m=firstpass; (m<lastpass); m++){
        printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
   }
   
   }*/
   
   
     printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, agemin, agemax);
     fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, agemin, agemax); 
   
     agegomp=(int)agemin;
     free_vector(severity,1,maxwav);
     free_imatrix(outcome,1,maxwav+1,1,n);
     free_vector(moisnais,1,n);
     free_vector(annais,1,n);
     /* free_matrix(mint,1,maxwav,1,n);
        free_matrix(anint,1,maxwav,1,n);*/
     free_vector(moisdc,1,n);
     free_vector(andc,1,n);
   
      
     wav=ivector(1,imx);
     dh=imatrix(1,lastpass-firstpass+1,1,imx);
     bh=imatrix(1,lastpass-firstpass+1,1,imx);
     mw=imatrix(1,lastpass-firstpass+1,1,imx);
      
     /* Concatenates waves */
     concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
   
     /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
   
     Tcode=ivector(1,100);
     nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
     ncodemax[1]=1;
     if (cptcovn > 0) tricode(Tvar,nbcode,imx);
         
     codtab=imatrix(1,100,1,10); /* Cross tabulation to get the order of 
                                    the estimations*/
     h=0;
     m=pow(2,cptcoveff);
    
     for(k=1;k<=cptcoveff; k++){
       for(i=1; i <=(m/pow(2,k));i++){
         for(j=1; j <= ncodemax[k]; j++){
           for(cpt=1; cpt <=(m/pow(2,cptcoveff+1-k)); cpt++){
             h++;
             if (h>m) h=1;codtab[h][k]=j;codtab[h][Tvar[k]]=j;
             /*  printf("h=%d k=%d j=%d codtab[h][k]=%d tvar[k]=%d \n",h, k,j,codtab[h][k],Tvar[k]);*/
           } 
         }
       }
     } 
     /* printf("codtab[1][2]=%d codtab[2][2]=%d",codtab[1][2],codtab[2][2]); 
        codtab[1][2]=1;codtab[2][2]=2; */
     /* for(i=1; i <=m ;i++){ 
        for(k=1; k <=cptcovn; k++){
        printf("i=%d k=%d %d %d ",i,k,codtab[i][k], cptcoveff);
        }
        printf("\n");
        }
        scanf("%d",i);*/
       
     /*------------ gnuplot -------------*/
     strcpy(optionfilegnuplot,optionfilefiname);
     if(mle==-3)
       strcat(optionfilegnuplot,"-mort");
     strcat(optionfilegnuplot,".gp");
   
     if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
       printf("Problem with file %s",optionfilegnuplot);
     }
     else{
       fprintf(ficgp,"\n# %s\n", version); 
       fprintf(ficgp,"# %s\n", optionfilegnuplot); 
       fprintf(ficgp,"set missing 'NaNq'\n");
     }
     /*  fclose(ficgp);*/
     /*--------- index.htm --------*/
   
     strcpy(optionfilehtm,optionfilefiname); /* Main html file */
     if(mle==-3)
       strcat(optionfilehtm,"-mort");
     strcat(optionfilehtm,".htm");
     if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
       printf("Problem with %s \n",optionfilehtm), exit(0);
     }
   
     strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
     strcat(optionfilehtmcov,"-cov.htm");
     if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
       printf("Problem with %s \n",optionfilehtmcov), exit(0);
     }
     else{
     fprintf(fichtmcov,"<body>\n<title>IMaCh Cov %s</title>\n <font size=\"2\">%s <br> %s</font> \
   <hr size=\"2\" color=\"#EC5E5E\"> \n\
   Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=%s<br>\n",\
             fileres,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
     }
   
     fprintf(fichtm,"<body>\n<title>IMaCh %s</title>\n <font size=\"2\">%s <br> %s</font> \
   <hr size=\"2\" color=\"#EC5E5E\"> \n\
   Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=%s<br>\n\
   \n\
   <hr  size=\"2\" color=\"#EC5E5E\">\
    <ul><li><h4>Parameter files</h4>\n\
    - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
    - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
    - Log file of the run: <a href=\"%s\">%s</a><br>\n\
    - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
    - Date and time at start: %s</ul>\n",\
             fileres,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
             optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
             fileres,fileres,\
             filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
     fflush(fichtm);
   
     strcpy(pathr,path);
     strcat(pathr,optionfilefiname);
     chdir(optionfilefiname); /* Move to directory named optionfile */
     
     /* Calculates basic frequencies. Computes observed prevalence at single age
        and prints on file fileres'p'. */
     freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart);
   
     fprintf(fichtm,"\n");
     fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
   Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
   Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
             imx,agemin,agemax,jmin,jmax,jmean);
     pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
       
      
     /* For Powell, parameters are in a vector p[] starting at p[1]
        so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
     p=param[1][1]; /* *(*(*(param +1)+1)+0) */
   
     globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
   
     if (mle==-3){
       ximort=matrix(1,NDIM,1,NDIM);
       cens=ivector(1,n);
       ageexmed=vector(1,n);
       agecens=vector(1,n);
       dcwave=ivector(1,n);
    
       for (i=1; i<=imx; i++){
         dcwave[i]=-1;
         for (m=firstpass; m<=lastpass; m++)
           if (s[m][i]>nlstate) {
             dcwave[i]=m;
             /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
             break;
           }
       }
   
       for (i=1; i<=imx; i++) {
         if (wav[i]>0){
           ageexmed[i]=agev[mw[1][i]][i];
           j=wav[i];
           agecens[i]=1.; 
   
           if (ageexmed[i]> 1 && wav[i] > 0){
             agecens[i]=agev[mw[j][i]][i];
             cens[i]= 1;
           }else if (ageexmed[i]< 1) 
             cens[i]= -1;
           if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
             cens[i]=0 ;
         }
         else cens[i]=-1;
       }
       
       for (i=1;i<=NDIM;i++) {
         for (j=1;j<=NDIM;j++)
           ximort[i][j]=(i == j ? 1.0 : 0.0);
       }
       
       p[1]=0.0268; p[NDIM]=0.083;
       /*printf("%lf %lf", p[1], p[2]);*/
       
       
       printf("Powell\n");  fprintf(ficlog,"Powell\n");
       strcpy(filerespow,"pow-mort"); 
       strcat(filerespow,fileres);
       if((ficrespow=fopen(filerespow,"w"))==NULL) {
         printf("Problem with resultfile: %s\n", filerespow);
         fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
       }
       fprintf(ficrespow,"# Powell\n# iter -2*LL");
       /*  for (i=1;i<=nlstate;i++)
           for(j=1;j<=nlstate+ndeath;j++)
           if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
       */
       fprintf(ficrespow,"\n");
       
       powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
       fclose(ficrespow);
       
       hesscov(matcov, p, NDIM, delti, 1e-4, gompertz); 
   
       for(i=1; i <=NDIM; i++)
         for(j=i+1;j<=NDIM;j++)
           matcov[i][j]=matcov[j][i];
       
       printf("\nCovariance matrix\n ");
       for(i=1; i <=NDIM; i++) {
         for(j=1;j<=NDIM;j++){ 
           printf("%f ",matcov[i][j]);
         }
         printf("\n ");
       }
       
       printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
       for (i=1;i<=NDIM;i++) 
         printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
   
       lsurv=vector(1,AGESUP);
       lpop=vector(1,AGESUP);
       tpop=vector(1,AGESUP);
       lsurv[agegomp]=100000;
       
       for (k=agegomp;k<=AGESUP;k++) {
         agemortsup=k;
         if (p[1]*exp(p[2]*(k-agegomp))>1) break;
       }
       
       for (k=agegomp;k<agemortsup;k++)
         lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
       
       for (k=agegomp;k<agemortsup;k++){
         lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
         sumlpop=sumlpop+lpop[k];
       }
       
       tpop[agegomp]=sumlpop;
       for (k=agegomp;k<(agemortsup-3);k++){
         /*  tpop[k+1]=2;*/
         tpop[k+1]=tpop[k]-lpop[k];
       }
       
       
       printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
       for (k=agegomp;k<(agemortsup-2);k++) 
         printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
       
       
       replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
       printinggnuplotmort(fileres, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
       
       printinghtmlmort(fileres,title,datafile, firstpass, lastpass, \
                        stepm, weightopt,\
                        model,imx,p,matcov,agemortsup);
       
       free_vector(lsurv,1,AGESUP);
       free_vector(lpop,1,AGESUP);
       free_vector(tpop,1,AGESUP);
     } /* Endof if mle==-3 */
     
     else{ /* For mle >=1 */
     
       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
       printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
       for (k=1; k<=npar;k++)
         printf(" %d %8.5f",k,p[k]);
       printf("\n");
       globpr=1; /* to print the contributions */
       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
       printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
       for (k=1; k<=npar;k++)
         printf(" %d %8.5f",k,p[k]);
       printf("\n");
       if(mle>=1){ /* Could be 1 or 2 */
         mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
       }
       
       /*--------- results files --------------*/
       fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate, ndeath, maxwav, weightopt,model);
       
       
       fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
       printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
       fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
       for(i=1,jk=1; i <=nlstate; i++){
         for(k=1; k <=(nlstate+ndeath); k++){
           if (k != i) {
             printf("%d%d ",i,k);
             fprintf(ficlog,"%d%d ",i,k);
             fprintf(ficres,"%1d%1d ",i,k);
             for(j=1; j <=ncovmodel; j++){
               printf("%f ",p[jk]);
               fprintf(ficlog,"%f ",p[jk]);
               fprintf(ficres,"%f ",p[jk]);
               jk++; 
             }
             printf("\n");
             fprintf(ficlog,"\n");
             fprintf(ficres,"\n");
           }
         }
       }
       if(mle!=0){
         /* Computing hessian and covariance matrix */
         ftolhess=ftol; /* Usually correct */
         hesscov(matcov, p, npar, delti, ftolhess, func);
       }
       fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
       printf("# Scales (for hessian or gradient estimation)\n");
       fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
       for(i=1,jk=1; i <=nlstate; i++){
         for(j=1; j <=nlstate+ndeath; j++){
           if (j!=i) {
             fprintf(ficres,"%1d%1d",i,j);
             printf("%1d%1d",i,j);
             fprintf(ficlog,"%1d%1d",i,j);
             for(k=1; k<=ncovmodel;k++){
               printf(" %.5e",delti[jk]);
               fprintf(ficlog," %.5e",delti[jk]);
               fprintf(ficres," %.5e",delti[jk]);
               jk++;
             }
             printf("\n");
             fprintf(ficlog,"\n");
             fprintf(ficres,"\n");
           }
         }
       }
       
       fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
       if(mle>=1)
         printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
       fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
       /* # 121 Var(a12)\n\ */
       /* # 122 Cov(b12,a12) Var(b12)\n\ */
       /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
       /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
       /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
       /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
       /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
       /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
       
       
       /* Just to have a covariance matrix which will be more understandable
          even is we still don't want to manage dictionary of variables
       */
       for(itimes=1;itimes<=2;itimes++){
         jj=0;
         for(i=1; i <=nlstate; i++){
           for(j=1; j <=nlstate+ndeath; j++){
             if(j==i) continue;
             for(k=1; k<=ncovmodel;k++){
               jj++;
               ca[0]= k+'a'-1;ca[1]='\0';
               if(itimes==1){
                 if(mle>=1)
                   printf("#%1d%1d%d",i,j,k);
                 fprintf(ficlog,"#%1d%1d%d",i,j,k);
                 fprintf(ficres,"#%1d%1d%d",i,j,k);
               }else{
                 if(mle>=1)
                   printf("%1d%1d%d",i,j,k);
                 fprintf(ficlog,"%1d%1d%d",i,j,k);
                 fprintf(ficres,"%1d%1d%d",i,j,k);
               }
               ll=0;
               for(li=1;li <=nlstate; li++){
                 for(lj=1;lj <=nlstate+ndeath; lj++){
                   if(lj==li) continue;
                   for(lk=1;lk<=ncovmodel;lk++){
                     ll++;
                     if(ll<=jj){
                       cb[0]= lk +'a'-1;cb[1]='\0';
                       if(ll<jj){
                         if(itimes==1){
                           if(mle>=1)
                             printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                           fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                           fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                         }else{
                           if(mle>=1)
                             printf(" %.5e",matcov[jj][ll]); 
                           fprintf(ficlog," %.5e",matcov[jj][ll]); 
                           fprintf(ficres," %.5e",matcov[jj][ll]); 
                         }
                       }else{
                         if(itimes==1){
                           if(mle>=1)
                             printf(" Var(%s%1d%1d)",ca,i,j);
                           fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                           fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                         }else{
                           if(mle>=1)
                             printf(" %.5e",matcov[jj][ll]); 
                           fprintf(ficlog," %.5e",matcov[jj][ll]); 
                           fprintf(ficres," %.5e",matcov[jj][ll]); 
                         }
                       }
                     }
                   } /* end lk */
                 } /* end lj */
               } /* end li */
               if(mle>=1)
                 printf("\n");
               fprintf(ficlog,"\n");
               fprintf(ficres,"\n");
               numlinepar++;
             } /* end k*/
           } /*end j */
         } /* end i */
       } /* end itimes */
       
       fflush(ficlog);
       fflush(ficres);
       
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         puts(line);
         fputs(line,ficparo);
       }
       ungetc(c,ficpar);
       
       estepm=0;
       fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm);
       if (estepm==0 || estepm < stepm) estepm=stepm;
       if (fage <= 2) {
         bage = ageminpar;
         fage = agemaxpar;
       }
       
       fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
       fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d\n",ageminpar,agemaxpar,bage,fage, estepm);
       fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d\n",ageminpar,agemaxpar,bage,fage, estepm);
       
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         puts(line);
         fputs(line,ficparo);
       }
       ungetc(c,ficpar);
       
       fscanf(ficpar,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav);
       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
       
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         puts(line);
         fputs(line,ficparo);
       }
       ungetc(c,ficpar);
       
       
       dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
       dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
       
       fscanf(ficpar,"pop_based=%d\n",&popbased);
       fprintf(ficparo,"pop_based=%d\n",popbased);   
       fprintf(ficres,"pop_based=%d\n",popbased);   
       
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         puts(line);
         fputs(line,ficparo);
       }
       ungetc(c,ficpar);
       
       fscanf(ficpar,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj);
       fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
       printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
       fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
       fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
       /* day and month of proj2 are not used but only year anproj2.*/
       
       
       
       /*  freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint);*/
       /*,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
       
       replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
       printinggnuplot(fileres, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
       
       printinghtml(fileres,title,datafile, firstpass, lastpass, stepm, weightopt,\
                    model,imx,jmin,jmax,jmean,rfileres,popforecast,estepm,\
                    jprev1,mprev1,anprev1,jprev2,mprev2,anprev2);
         
      /*------------ free_vector  -------------*/
      /*  chdir(path); */
    
       free_ivector(wav,1,imx);
       free_imatrix(dh,1,lastpass-firstpass+1,1,imx);
       free_imatrix(bh,1,lastpass-firstpass+1,1,imx);
       free_imatrix(mw,1,lastpass-firstpass+1,1,imx);   
       free_lvector(num,1,n);
       free_vector(agedc,1,n);
       /*free_matrix(covar,0,NCOVMAX,1,n);*/
       /*free_matrix(covar,1,NCOVMAX,1,n);*/
       fclose(ficparo);
       fclose(ficres);
   
   
       /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
     
       strcpy(filerespl,"pl");
       strcat(filerespl,fileres);
       if((ficrespl=fopen(filerespl,"w"))==NULL) {
         printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);goto end;
         fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);goto end;
       }
       printf("Computing period (stable) prevalence: result on file '%s' \n", filerespl);
       fprintf(ficlog,"Computing period (stable) prevalence: result on file '%s' \n", filerespl);
       pstamp(ficrespl);
       fprintf(ficrespl,"# Period (stable) prevalence \n");
       fprintf(ficrespl,"#Age ");
       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
       fprintf(ficrespl,"\n");
     
       prlim=matrix(1,nlstate,1,nlstate);
   
       agebase=ageminpar;
       agelim=agemaxpar;
       ftolpl=1.e-10;
       i1=cptcoveff;
       if (cptcovn < 1){i1=1;}
   
       for(cptcov=1,k=0;cptcov<=i1;cptcov++){
         for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
           k=k+1;
           /*printf("cptcov=%d cptcod=%d codtab=%d nbcode=%d\n",cptcov, cptcod,Tcode[cptcode],codtab[cptcod][cptcov]);*/
           fprintf(ficrespl,"\n#******");
           printf("\n#******");
           fprintf(ficlog,"\n#******");
           for(j=1;j<=cptcoveff;j++) {
             fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
             printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
             fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
           }
           fprintf(ficrespl,"******\n");
           printf("******\n");
           fprintf(ficlog,"******\n");
           
           for (age=agebase; age<=agelim; age++){
             prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);
             fprintf(ficrespl,"%.0f ",age );
             for(j=1;j<=cptcoveff;j++)
               fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
             for(i=1; i<=nlstate;i++)
               fprintf(ficrespl," %.5f", prlim[i][i]);
             fprintf(ficrespl,"\n");
           }
         }
       }
       fclose(ficrespl);
   
       /*------------- h Pij x at various ages ------------*/
     
       strcpy(filerespij,"pij");  strcat(filerespij,fileres);
       if((ficrespij=fopen(filerespij,"w"))==NULL) {
         printf("Problem with Pij resultfile: %s\n", filerespij);goto end;
         fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij);goto end;
       }
       printf("Computing pij: result on file '%s' \n", filerespij);
       fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
     
       stepsize=(int) (stepm+YEARM-1)/YEARM;
       /*if (stepm<=24) stepsize=2;*/
   
       agelim=AGESUP;
       hstepm=stepsize*YEARM; /* Every year of age */
       hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
   
       /* hstepm=1;   aff par mois*/
       pstamp(ficrespij);
       fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
       for(cptcov=1,k=0;cptcov<=i1;cptcov++){
         for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
           k=k+1;
           fprintf(ficrespij,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) 
             fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
           fprintf(ficrespij,"******\n");
           
           for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
             nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
             nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
   
             /*      nhstepm=nhstepm*YEARM; aff par mois*/
   
             p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             oldm=oldms;savm=savms;
             hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
             fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
             for(i=1; i<=nlstate;i++)
               for(j=1; j<=nlstate+ndeath;j++)
                 fprintf(ficrespij," %1d-%1d",i,j);
             fprintf(ficrespij,"\n");
             for (h=0; h<=nhstepm; h++){
               fprintf(ficrespij,"%d %3.f %3.f",k,agedeb, agedeb+ h*hstepm/YEARM*stepm );
               for(i=1; i<=nlstate;i++)
                 for(j=1; j<=nlstate+ndeath;j++)
                   fprintf(ficrespij," %.5f", p3mat[i][j][h]);
               fprintf(ficrespij,"\n");
             }
             free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             fprintf(ficrespij,"\n");
           }
         }
       }
   
       varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
   
       fclose(ficrespij);
   
       probs= ma3x(1,AGESUP,1,NCOVMAX, 1,NCOVMAX);
       for(i=1;i<=AGESUP;i++)
         for(j=1;j<=NCOVMAX;j++)
           for(k=1;k<=NCOVMAX;k++)
             probs[i][j][k]=0.;
   
       /*---------- Forecasting ------------------*/
       /*if((stepm == 1) && (strcmp(model,".")==0)){*/
       if(prevfcast==1){
         /*    if(stepm ==1){*/
         prevforecast(fileres, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
         /* (popforecast==1) populforecast(fileres, anpyram,mpyram,jpyram, agemin,agemax, dateprev1, dateprev2,mobilav, agedeb, fage, popforecast, popfile, anpyram1,p, i1);*/
         /*      }  */
         /*      else{ */
         /*        erreur=108; */
         /*        printf("Warning %d!! You can only forecast the prevalences if the optimization\n  has been performed with stepm = 1 (month) instead of %d or model=. instead of '%s'\n", erreur, stepm, model); */
         /*        fprintf(ficlog,"Warning %d!! You can only forecast the prevalences if the optimization\n  has been performed with stepm = 1 (month) instead of %d or model=. instead of '%s'\n", erreur, stepm, model); */
         /*      } */
       }
     
   
       /*---------- Health expectancies and variances ------------*/
   
       strcpy(filerest,"t");
       strcat(filerest,fileres);
       if((ficrest=fopen(filerest,"w"))==NULL) {
         printf("Problem with total LE resultfile: %s\n", filerest);goto end;
         fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
       }
       printf("Computing Total Life expectancies with their standard errors: file '%s' \n", filerest); 
       fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' \n", filerest); 
   
   
       strcpy(filerese,"e");
       strcat(filerese,fileres);
       if((ficreseij=fopen(filerese,"w"))==NULL) {
         printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
         fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
       }
       printf("Computing Health Expectancies: result on file '%s' \n", filerese);
       fprintf(ficlog,"Computing Health Expectancies: result on file '%s' \n", filerese);
   
       strcpy(fileresstde,"stde");
       strcat(fileresstde,fileres);
       if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
         printf("Problem with Health Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
         fprintf(ficlog,"Problem with Health Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
       }
       printf("Computing Health Expectancies and standard errors: result on file '%s' \n", fileresstde);
       fprintf(ficlog,"Computing Health Expectancies and standard errors: result on file '%s' \n", fileresstde);
   
       strcpy(filerescve,"cve");
       strcat(filerescve,fileres);
       if((ficrescveij=fopen(filerescve,"w"))==NULL) {
         printf("Problem with Covar. Health Exp. resultfile: %s\n", filerescve); exit(0);
         fprintf(ficlog,"Problem with Covar. Health Exp. resultfile: %s\n", filerescve); exit(0);
       }
       printf("Computing Covar. of Health Expectancies: result on file '%s' \n", filerescve);
       fprintf(ficlog,"Computing Covar. of Health Expectancies: result on file '%s' \n", filerescve);
   
       strcpy(fileresv,"v");
       strcat(fileresv,fileres);
       if((ficresvij=fopen(fileresv,"w"))==NULL) {
         printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
         fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
       }
       printf("Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);
       fprintf(ficlog,"Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);
   
       /* Computes prevalence between agemin (i.e minimal age computed) and no more ageminpar */
       prevalence(probs, agemin, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
       /*  printf("ageminpar=%f, agemax=%f, s[lastpass][imx]=%d, agev[lastpass][imx]=%f, nlstate=%d, imx=%d,  mint[lastpass][imx]=%f, anint[lastpass][imx]=%f,dateprev1=%f, dateprev2=%f, firstpass=%d, lastpass=%d\n",\
           ageminpar, agemax, s[lastpass][imx], agev[lastpass][imx], nlstate, imx, mint[lastpass][imx],anint[lastpass][imx], dateprev1, dateprev2, firstpass, lastpass);
       */
   
       if (mobilav!=0) {
         mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
         if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){
           fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
           printf(" Error in movingaverage mobilav=%d\n",mobilav);
         }
       }
   
       for(cptcov=1,k=0;cptcov<=i1;cptcov++){
         for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
           k=k+1; 
           fprintf(ficrest,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) 
             fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
           fprintf(ficrest,"******\n");
   
           fprintf(ficreseij,"\n#****** ");
           fprintf(ficresstdeij,"\n#****** ");
           fprintf(ficrescveij,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) {
             fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
             fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
             fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
           }
           fprintf(ficreseij,"******\n");
           fprintf(ficresstdeij,"******\n");
           fprintf(ficrescveij,"******\n");
   
           fprintf(ficresvij,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) 
             fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
           fprintf(ficresvij,"******\n");
   
           eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
           oldm=oldms;savm=savms;
           evsij(fileres, eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart);  
           cvevsij(fileres, eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart);  
    
           vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
           oldm=oldms;savm=savms;
           varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k, estepm, cptcov,cptcod,0, mobilav, strstart);
           if(popbased==1){
             varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k, estepm, cptcov,cptcod,popbased,mobilav, strstart);
           }
   
           pstamp(ficrest);
           fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n# Age ( e.. (std) ");
           for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
           fprintf(ficrest,"\n");
   
           epj=vector(1,nlstate+1);
           for(age=bage; age <=fage ;age++){
             prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);
             if (popbased==1) {
               if(mobilav ==0){
                 for(i=1; i<=nlstate;i++)
                   prlim[i][i]=probs[(int)age][i][k];
               }else{ /* mobilav */ 
                 for(i=1; i<=nlstate;i++)
                   prlim[i][i]=mobaverage[(int)age][i][k];
               }
             }
           
             fprintf(ficrest," %4.0f",age);
             for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
               for(i=1, epj[j]=0.;i <=nlstate;i++) {
                 epj[j] += prlim[i][i]*eij[i][j][(int)age];
                 /*  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
               }
               epj[nlstate+1] +=epj[j];
             }
   
             for(i=1, vepp=0.;i <=nlstate;i++)
               for(j=1;j <=nlstate;j++)
                 vepp += vareij[i][j][(int)age];
             fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
             for(j=1;j <=nlstate;j++){
               fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
             }
             fprintf(ficrest,"\n");
           }
           free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
           free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
           free_vector(epj,1,nlstate+1);
         }
       }
       free_vector(weight,1,n);
       free_imatrix(Tvard,1,15,1,2);
       free_imatrix(s,1,maxwav+1,1,n);
       free_matrix(anint,1,maxwav,1,n); 
       free_matrix(mint,1,maxwav,1,n);
       free_ivector(cod,1,n);
       free_ivector(tab,1,NCOVMAX);
       fclose(ficreseij);
       fclose(ficresstdeij);
       fclose(ficrescveij);
       fclose(ficresvij);
       fclose(ficrest);
       fclose(ficpar);
     
       /*------- Variance of period (stable) prevalence------*/   
   
       strcpy(fileresvpl,"vpl");
       strcat(fileresvpl,fileres);
       if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
         printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
         exit(0);
       }
       printf("Computing Variance-covariance of period (stable) prevalence: file '%s' \n", fileresvpl);
   
       for(cptcov=1,k=0;cptcov<=i1;cptcov++){
         for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
           k=k+1;
           fprintf(ficresvpl,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) 
             fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
           fprintf(ficresvpl,"******\n");
         
           varpl=matrix(1,nlstate,(int) bage, (int) fage);
           oldm=oldms;savm=savms;
           varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k,strstart);
           free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
         }
       }
   
       fclose(ficresvpl);
   
       /*---------- End : free ----------------*/
       if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       free_ma3x(probs,1,AGESUP,1,NCOVMAX, 1,NCOVMAX);
   
     }  /* mle==-3 arrives here for freeing */
     free_matrix(prlim,1,nlstate,1,nlstate);
       free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
       free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
       free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
       free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
       free_matrix(covar,0,NCOVMAX,1,n);
       free_matrix(matcov,1,npar,1,npar);
       /*free_vector(delti,1,npar);*/
       free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
       free_matrix(agev,1,maxwav,1,imx);
       free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
   
       free_ivector(ncodemax,1,8);
       free_ivector(Tvar,1,15);
       free_ivector(Tprod,1,15);
       free_ivector(Tvaraff,1,15);
       free_ivector(Tage,1,15);
       free_ivector(Tcode,1,100);
   
       free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
       free_imatrix(codtab,1,100,1,10);
     fflush(fichtm);
     fflush(ficgp);
     
   
     if((nberr >0) || (nbwarn>0)){
       printf("End of Imach with %d errors and/or %d warnings\n",nberr,nbwarn);
       fprintf(ficlog,"End of Imach with %d errors and/or warnings %d\n",nberr,nbwarn);
     }else{
       printf("End of Imach\n");
       fprintf(ficlog,"End of Imach\n");
     }
     printf("See log file on %s\n",filelog);
     /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
     (void) gettimeofday(&end_time,&tzp);
     tm = *localtime(&end_time.tv_sec);
     tmg = *gmtime(&end_time.tv_sec);
     strcpy(strtend,asctime(&tm));
     printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
     fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
     printf("Total time used %s\n", asc_diff_time(end_time.tv_sec -start_time.tv_sec,tmpout));
   
     printf("Total time was %d Sec.\n", end_time.tv_sec -start_time.tv_sec);
     fprintf(ficlog,"Total time used %s\n", asc_diff_time(end_time.tv_sec -start_time.tv_sec,tmpout));
     fprintf(ficlog,"Total time was %d Sec.\n", end_time.tv_sec -start_time.tv_sec);
     /*  printf("Total time was %d uSec.\n", total_usecs);*/
   /*   if(fileappend(fichtm,optionfilehtm)){ */
     fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>",strstart, strtend);
     fclose(fichtm);
     fclose(fichtmcov);
     fclose(ficgp);
     fclose(ficlog);
     /*------ End -----------*/
   
   
      printf("Before Current directory %s!\n",pathcd);
      if(chdir(pathcd) != 0)
       printf("Can't move to directory %s!\n",path);
     if(getcwd(pathcd,MAXLINE) > 0)
       printf("Current directory %s!\n",pathcd);
     /*strcat(plotcmd,CHARSEPARATOR);*/
     sprintf(plotcmd,"gnuplot");
   #ifndef UNIX
     sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
   #endif
     if(!stat(plotcmd,&info)){
       printf("Error gnuplot program not found: %s\n",plotcmd);fflush(stdout);
       if(!stat(getenv("GNUPLOTBIN"),&info)){
         printf("Error gnuplot program not found: %s Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
       }else
         strcpy(pplotcmd,plotcmd);
   #ifdef UNIX
       strcpy(plotcmd,GNUPLOTPROGRAM);
       if(!stat(plotcmd,&info)){
         printf("Error gnuplot program not found: %s\n",plotcmd);fflush(stdout);
       }else
         strcpy(pplotcmd,plotcmd);
   #endif
     }else
       strcpy(pplotcmd,plotcmd);
     
     sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
     printf("Starting graphs with: %s\n",plotcmd);fflush(stdout);
   
     if((outcmd=system(plotcmd)) != 0){
       printf("\n Problem with gnuplot\n");
     }
     printf(" Wait...");
     while (z[0] != 'q') {
       /* chdir(path); */
       printf("\nType e to edit output files, g to graph again and q for exiting: ");
       scanf("%s",z);
   /*     if (z[0] == 'c') system("./imach"); */
       if (z[0] == 'e') {
         printf("Starting browser with: %s",optionfilehtm);fflush(stdout);
         system(optionfilehtm);
       }
       else if (z[0] == 'g') system(plotcmd);
       else if (z[0] == 'q') exit(0);
     }
     end:
     while (z[0] != 'q') {
       printf("\nType  q for exiting: ");
       scanf("%s",z);
     }
   }
   
   
   

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  Added in v.1.120


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