Diff for /imach/src/imach.c between versions 1.14 and 1.153

version 1.14, 2002/02/20 17:05:44 version 1.153, 2014/06/20 16:45:46
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      /* $Id$
 /*********************** Imach **************************************            $State$
   This program computes Healthy Life Expectancies from cross-longitudinal    $Log$
   data. Cross-longitudinal consist in a first survey ("cross") where    Revision 1.153  2014/06/20 16:45:46  brouard
   individuals from different ages are interviewed on their health status    Summary: If 3 live state, convergence to period prevalence on same graph
   or degree of  disability. At least a second wave of interviews    Author: Brouard
   ("longitudinal") should  measure each new individual health status.  
   Health expectancies are computed from the transistions observed between    Revision 1.152  2014/06/18 17:54:09  brouard
   waves and are computed for each degree of severity of disability (number    Summary: open browser, use gnuplot on same dir than imach if not found in the path
   of life states). More degrees you consider, more time is necessary to  
   reach the Maximum Likelihood of the parameters involved in the model.    Revision 1.151  2014/06/18 16:43:30  brouard
   The simplest model is the multinomial logistic model where pij is    *** empty log message ***
   the probabibility to be observed in state j at the second wave conditional  
   to be observed in state i at the first wave. Therefore the model is:    Revision 1.150  2014/06/18 16:42:35  brouard
   log(pij/pii)= aij + bij*age+ cij*sex + etc , where 'age' is age and 'sex'    Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
   is a covariate. If you want to have a more complex model than "constant and    Author: brouard
   age", you should modify the program where the markup  
     *Covariates have to be included here again* invites you to do it.    Revision 1.149  2014/06/18 15:51:14  brouard
   More covariates you add, less is the speed of the convergence.    Summary: Some fixes in parameter files errors
     Author: Nicolas Brouard
   The advantage that this computer programme claims, comes from that if the  
   delay between waves is not identical for each individual, or if some    Revision 1.148  2014/06/17 17:38:48  brouard
   individual missed an interview, the information is not rounded or lost, but    Summary: Nothing new
   taken into account using an interpolation or extrapolation.    Author: Brouard
   hPijx is the probability to be  
   observed in state i at age x+h conditional to the observed state i at age    Just a new packaging for OS/X version 0.98nS
   x. The delay 'h' can be split into an exact number (nh*stepm) of  
   unobserved intermediate  states. This elementary transition (by month or    Revision 1.147  2014/06/16 10:33:11  brouard
   quarter trimester, semester or year) is model as a multinomial logistic.    *** empty log message ***
   The hPx matrix is simply the matrix product of nh*stepm elementary matrices  
   and the contribution of each individual to the likelihood is simply hPijx.    Revision 1.146  2014/06/16 10:20:28  brouard
     Summary: Merge
   Also this programme outputs the covariance matrix of the parameters but also    Author: Brouard
   of the life expectancies. It also computes the prevalence limits.  
      Merge, before building revised version.
   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).  
            Institut national d'études démographiques, Paris.    Revision 1.145  2014/06/10 21:23:15  brouard
   This software have been partly granted by Euro-REVES, a concerted action    Summary: Debugging with valgrind
   from the European Union.    Author: Nicolas Brouard
   It is copyrighted identically to a GNU software product, ie programme and  
   software can be distributed freely for non commercial use. Latest version    Lot of changes in order to output the results with some covariates
   can be accessed at http://euroreves.ined.fr/imach .    After the Edimburgh REVES conference 2014, it seems mandatory to
   **********************************************************************/    improve the code.
      No more memory valgrind error but a lot has to be done in order to
 #include <math.h>    continue the work of splitting the code into subroutines.
 #include <stdio.h>    Also, decodemodel has been improved. Tricode is still not
 #include <stdlib.h>    optimal. nbcode should be improved. Documentation has been added in
 #include <unistd.h>    the source code.
   
 #define MAXLINE 256    Revision 1.143  2014/01/26 09:45:38  brouard
 #define FILENAMELENGTH 80    Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
 /*#define DEBUG*/  
 #define windows    * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
 #define GLOCK_ERROR_NOPATH              -1      /* empty path */    (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
 #define GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */  
     Revision 1.142  2014/01/26 03:57:36  brouard
 #define MAXPARM 30 /* Maximum number of parameters for the optimization */    Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
 #define NPARMAX 64 /* (nlstate+ndeath-1)*nlstate*ncovmodel */  
     * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
 #define NINTERVMAX 8  
 #define NLSTATEMAX 8 /* Maximum number of live states (for func) */    Revision 1.141  2014/01/26 02:42:01  brouard
 #define NDEATHMAX 8 /* Maximum number of dead states (for func) */    * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
 #define NCOVMAX 8 /* Maximum number of covariates */  
 #define MAXN 20000    Revision 1.140  2011/09/02 10:37:54  brouard
 #define YEARM 12. /* Number of months per year */    Summary: times.h is ok with mingw32 now.
 #define AGESUP 130  
 #define AGEBASE 40    Revision 1.139  2010/06/14 07:50:17  brouard
     After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
     I remember having already fixed agemin agemax which are pointers now but not cvs saved.
 int nvar;  
 int cptcovn, cptcovage=0, cptcoveff=0,cptcov;    Revision 1.138  2010/04/30 18:19:40  brouard
 int npar=NPARMAX;    *** empty log message ***
 int nlstate=2; /* Number of live states */  
 int ndeath=1; /* Number of dead states */    Revision 1.137  2010/04/29 18:11:38  brouard
 int ncovmodel, ncov;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */    (Module): Checking covariates for more complex models
 int popbased=0, fprev,lprev;    than V1+V2. A lot of change to be done. Unstable.
   
 int *wav; /* Number of waves for this individuual 0 is possible */    Revision 1.136  2010/04/26 20:30:53  brouard
 int maxwav; /* Maxim number of waves */    (Module): merging some libgsl code. Fixing computation
 int jmin, jmax; /* min, max spacing between 2 waves */    of likelione (using inter/intrapolation if mle = 0) in order to
 int mle, weightopt;    get same likelihood as if mle=1.
 int **mw; /* mw[mi][i] is number of the mi wave for this individual */    Some cleaning of code and comments added.
 int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */  
 double jmean; /* Mean space between 2 waves */    Revision 1.135  2009/10/29 15:33:14  brouard
 double **oldm, **newm, **savm; /* Working pointers to matrices */    (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
 double **oldms, **newms, **savms; /* Fixed working pointers to matrices */  
 FILE *fic,*ficpar, *ficparo,*ficres,  *ficrespl, *ficrespij, *ficrest,*ficresf;    Revision 1.134  2009/10/29 13:18:53  brouard
 FILE *ficgp, *fichtm,*ficresprob;    (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
 FILE *ficreseij;  
   char filerese[FILENAMELENGTH];    Revision 1.133  2009/07/06 10:21:25  brouard
  FILE  *ficresvij;    just nforces
   char fileresv[FILENAMELENGTH];  
  FILE  *ficresvpl;    Revision 1.132  2009/07/06 08:22:05  brouard
   char fileresvpl[FILENAMELENGTH];    Many tings
   
 #define NR_END 1    Revision 1.131  2009/06/20 16:22:47  brouard
 #define FREE_ARG char*    Some dimensions resccaled
 #define FTOL 1.0e-10  
     Revision 1.130  2009/05/26 06:44:34  brouard
 #define NRANSI    (Module): Max Covariate is now set to 20 instead of 8. A
 #define ITMAX 200    lot of cleaning with variables initialized to 0. Trying to make
     V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
 #define TOL 2.0e-4  
     Revision 1.129  2007/08/31 13:49:27  lievre
 #define CGOLD 0.3819660    Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
 #define ZEPS 1.0e-10  
 #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d);    Revision 1.128  2006/06/30 13:02:05  brouard
     (Module): Clarifications on computing e.j
 #define GOLD 1.618034  
 #define GLIMIT 100.0    Revision 1.127  2006/04/28 18:11:50  brouard
 #define TINY 1.0e-20    (Module): Yes the sum of survivors was wrong since
     imach-114 because nhstepm was no more computed in the age
 static double maxarg1,maxarg2;    loop. Now we define nhstepma in the age loop.
 #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))    (Module): In order to speed up (in case of numerous covariates) we
 #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))    compute health expectancies (without variances) in a first step
      and then all the health expectancies with variances or standard
 #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))    deviation (needs data from the Hessian matrices) which slows the
 #define rint(a) floor(a+0.5)    computation.
     In the future we should be able to stop the program is only health
 static double sqrarg;    expectancies and graph are needed without standard deviations.
 #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)  
 #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;}    Revision 1.126  2006/04/28 17:23:28  brouard
     (Module): Yes the sum of survivors was wrong since
 int imx;    imach-114 because nhstepm was no more computed in the age
 int stepm;    loop. Now we define nhstepma in the age loop.
 /* Stepm, step in month: minimum step interpolation*/    Version 0.98h
   
 int m,nb;    Revision 1.125  2006/04/04 15:20:31  lievre
 int *num, firstpass=0, lastpass=4,*cod, *ncodemax, *Tage;    Errors in calculation of health expectancies. Age was not initialized.
 double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;    Forecasting file added.
 double **pmmij, ***probs, ***mobaverage;  
     Revision 1.124  2006/03/22 17:13:53  lievre
 double *weight;    Parameters are printed with %lf instead of %f (more numbers after the comma).
 int **s; /* Status */    The log-likelihood is printed in the log file
 double *agedc, **covar, idx;  
 int **nbcode, *Tcode, *Tvar, **codtab, **Tvard, *Tprod, cptcovprod, *Tvaraff;    Revision 1.123  2006/03/20 10:52:43  brouard
     * imach.c (Module): <title> changed, corresponds to .htm file
 double ftol=FTOL; /* Tolerance for computing Max Likelihood */    name. <head> headers where missing.
 double ftolhess; /* Tolerance for computing hessian */  
     * imach.c (Module): Weights can have a decimal point as for
 /**************** split *************************/    English (a comma might work with a correct LC_NUMERIC environment,
 static  int split( char *path, char *dirc, char *name )    otherwise the weight is truncated).
 {    Modification of warning when the covariates values are not 0 or
    char *s;                             /* pointer */    1.
    int  l1, l2;                         /* length counters */    Version 0.98g
   
    l1 = strlen( path );                 /* length of path */    Revision 1.122  2006/03/20 09:45:41  brouard
    if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );    (Module): Weights can have a decimal point as for
    s = strrchr( path, '\\' );           /* find last / */    English (a comma might work with a correct LC_NUMERIC environment,
    if ( s == NULL ) {                   /* no directory, so use current */    otherwise the weight is truncated).
 #if     defined(__bsd__)                /* get current working directory */    Modification of warning when the covariates values are not 0 or
       extern char       *getwd( );    1.
     Version 0.98g
       if ( getwd( dirc ) == NULL ) {  
 #else    Revision 1.121  2006/03/16 17:45:01  lievre
       extern char       *getcwd( );    * imach.c (Module): Comments concerning covariates added
   
       if ( getcwd( dirc, FILENAME_MAX ) == NULL ) {    * imach.c (Module): refinements in the computation of lli if
 #endif    status=-2 in order to have more reliable computation if stepm is
          return( GLOCK_ERROR_GETCWD );    not 1 month. Version 0.98f
       }  
       strcpy( name, path );             /* we've got it */    Revision 1.120  2006/03/16 15:10:38  lievre
    } else {                             /* strip direcotry from path */    (Module): refinements in the computation of lli if
       s++;                              /* after this, the filename */    status=-2 in order to have more reliable computation if stepm is
       l2 = strlen( s );                 /* length of filename */    not 1 month. Version 0.98f
       if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );  
       strcpy( name, s );                /* save file name */    Revision 1.119  2006/03/15 17:42:26  brouard
       strncpy( dirc, path, l1 - l2 );   /* now the directory */    (Module): Bug if status = -2, the loglikelihood was
       dirc[l1-l2] = 0;                  /* add zero */    computed as likelihood omitting the logarithm. Version O.98e
    }  
    l1 = strlen( dirc );                 /* length of directory */    Revision 1.118  2006/03/14 18:20:07  brouard
    if ( dirc[l1-1] != '\\' ) { dirc[l1] = '\\'; dirc[l1+1] = 0; }    (Module): varevsij Comments added explaining the second
    return( 0 );                         /* we're done */    table of variances if popbased=1 .
 }    (Module): Covariances of eij, ekl added, graphs fixed, new html link.
     (Module): Function pstamp added
     (Module): Version 0.98d
 /******************************************/  
     Revision 1.117  2006/03/14 17:16:22  brouard
 void replace(char *s, char*t)    (Module): varevsij Comments added explaining the second
 {    table of variances if popbased=1 .
   int i;    (Module): Covariances of eij, ekl added, graphs fixed, new html link.
   int lg=20;    (Module): Function pstamp added
   i=0;    (Module): Version 0.98d
   lg=strlen(t);  
   for(i=0; i<= lg; i++) {    Revision 1.116  2006/03/06 10:29:27  brouard
     (s[i] = t[i]);    (Module): Variance-covariance wrong links and
     if (t[i]== '\\') s[i]='/';    varian-covariance of ej. is needed (Saito).
   }  
 }    Revision 1.115  2006/02/27 12:17:45  brouard
     (Module): One freematrix added in mlikeli! 0.98c
 int nbocc(char *s, char occ)  
 {    Revision 1.114  2006/02/26 12:57:58  brouard
   int i,j=0;    (Module): Some improvements in processing parameter
   int lg=20;    filename with strsep.
   i=0;  
   lg=strlen(s);    Revision 1.113  2006/02/24 14:20:24  brouard
   for(i=0; i<= lg; i++) {    (Module): Memory leaks checks with valgrind and:
   if  (s[i] == occ ) j++;    datafile was not closed, some imatrix were not freed and on matrix
   }    allocation too.
   return j;  
 }    Revision 1.112  2006/01/30 09:55:26  brouard
     (Module): Back to gnuplot.exe instead of wgnuplot.exe
 void cutv(char *u,char *v, char*t, char occ)  
 {    Revision 1.111  2006/01/25 20:38:18  brouard
   int i,lg,j,p=0;    (Module): Lots of cleaning and bugs added (Gompertz)
   i=0;    (Module): Comments can be added in data file. Missing date values
   for(j=0; j<=strlen(t)-1; j++) {    can be a simple dot '.'.
     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1;  
   }    Revision 1.110  2006/01/25 00:51:50  brouard
     (Module): Lots of cleaning and bugs added (Gompertz)
   lg=strlen(t);  
   for(j=0; j<p; j++) {    Revision 1.109  2006/01/24 19:37:15  brouard
     (u[j] = t[j]);    (Module): Comments (lines starting with a #) are allowed in data.
   }  
      u[p]='\0';    Revision 1.108  2006/01/19 18:05:42  lievre
     Gnuplot problem appeared...
    for(j=0; j<= lg; j++) {    To be fixed
     if (j>=(p+1))(v[j-p-1] = t[j]);  
   }    Revision 1.107  2006/01/19 16:20:37  brouard
 }    Test existence of gnuplot in imach path
   
 /********************** nrerror ********************/    Revision 1.106  2006/01/19 13:24:36  brouard
     Some cleaning and links added in html output
 void nrerror(char error_text[])  
 {    Revision 1.105  2006/01/05 20:23:19  lievre
   fprintf(stderr,"ERREUR ...\n");    *** empty log message ***
   fprintf(stderr,"%s\n",error_text);  
   exit(1);    Revision 1.104  2005/09/30 16:11:43  lievre
 }    (Module): sump fixed, loop imx fixed, and simplifications.
 /*********************** vector *******************/    (Module): If the status is missing at the last wave but we know
 double *vector(int nl, int nh)    that the person is alive, then we can code his/her status as -2
 {    (instead of missing=-1 in earlier versions) and his/her
   double *v;    contributions to the likelihood is 1 - Prob of dying from last
   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));    health status (= 1-p13= p11+p12 in the easiest case of somebody in
   if (!v) nrerror("allocation failure in vector");    the healthy state at last known wave). Version is 0.98
   return v-nl+NR_END;  
 }    Revision 1.103  2005/09/30 15:54:49  lievre
     (Module): sump fixed, loop imx fixed, and simplifications.
 /************************ free vector ******************/  
 void free_vector(double*v, int nl, int nh)    Revision 1.102  2004/09/15 17:31:30  brouard
 {    Add the possibility to read data file including tab characters.
   free((FREE_ARG)(v+nl-NR_END));  
 }    Revision 1.101  2004/09/15 10:38:38  brouard
     Fix on curr_time
 /************************ivector *******************************/  
 int *ivector(long nl,long nh)    Revision 1.100  2004/07/12 18:29:06  brouard
 {    Add version for Mac OS X. Just define UNIX in Makefile
   int *v;  
   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));    Revision 1.99  2004/06/05 08:57:40  brouard
   if (!v) nrerror("allocation failure in ivector");    *** empty log message ***
   return v-nl+NR_END;  
 }    Revision 1.98  2004/05/16 15:05:56  brouard
     New version 0.97 . First attempt to estimate force of mortality
 /******************free ivector **************************/    directly from the data i.e. without the need of knowing the health
 void free_ivector(int *v, long nl, long nh)    state at each age, but using a Gompertz model: log u =a + b*age .
 {    This is the basic analysis of mortality and should be done before any
   free((FREE_ARG)(v+nl-NR_END));    other analysis, in order to test if the mortality estimated from the
 }    cross-longitudinal survey is different from the mortality estimated
     from other sources like vital statistic data.
 /******************* imatrix *******************************/  
 int **imatrix(long nrl, long nrh, long ncl, long nch)    The same imach parameter file can be used but the option for mle should be -3.
      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */  
 {    Agnès, who wrote this part of the code, tried to keep most of the
   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1;    former routines in order to include the new code within the former code.
   int **m;  
      The output is very simple: only an estimate of the intercept and of
   /* allocate pointers to rows */    the slope with 95% confident intervals.
   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*)));  
   if (!m) nrerror("allocation failure 1 in matrix()");    Current limitations:
   m += NR_END;    A) Even if you enter covariates, i.e. with the
   m -= nrl;    model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
      B) There is no computation of Life Expectancy nor Life Table.
    
   /* allocate rows and set pointers to them */    Revision 1.97  2004/02/20 13:25:42  lievre
   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int)));    Version 0.96d. Population forecasting command line is (temporarily)
   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");    suppressed.
   m[nrl] += NR_END;  
   m[nrl] -= ncl;    Revision 1.96  2003/07/15 15:38:55  brouard
      * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol;    rewritten within the same printf. Workaround: many printfs.
    
   /* return pointer to array of pointers to rows */    Revision 1.95  2003/07/08 07:54:34  brouard
   return m;    * imach.c (Repository):
 }    (Repository): Using imachwizard code to output a more meaningful covariance
     matrix (cov(a12,c31) instead of numbers.
 /****************** free_imatrix *************************/  
 void free_imatrix(m,nrl,nrh,ncl,nch)    Revision 1.94  2003/06/27 13:00:02  brouard
       int **m;    Just cleaning
       long nch,ncl,nrh,nrl;  
      /* free an int matrix allocated by imatrix() */    Revision 1.93  2003/06/25 16:33:55  brouard
 {    (Module): On windows (cygwin) function asctime_r doesn't
   free((FREE_ARG) (m[nrl]+ncl-NR_END));    exist so I changed back to asctime which exists.
   free((FREE_ARG) (m+nrl-NR_END));    (Module): Version 0.96b
 }  
     Revision 1.92  2003/06/25 16:30:45  brouard
 /******************* matrix *******************************/    (Module): On windows (cygwin) function asctime_r doesn't
 double **matrix(long nrl, long nrh, long ncl, long nch)    exist so I changed back to asctime which exists.
 {  
   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;    Revision 1.91  2003/06/25 15:30:29  brouard
   double **m;    * imach.c (Repository): Duplicated warning errors corrected.
     (Repository): Elapsed time after each iteration is now output. It
   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));    helps to forecast when convergence will be reached. Elapsed time
   if (!m) nrerror("allocation failure 1 in matrix()");    is stamped in powell.  We created a new html file for the graphs
   m += NR_END;    concerning matrix of covariance. It has extension -cov.htm.
   m -= nrl;  
     Revision 1.90  2003/06/24 12:34:15  brouard
   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));    (Module): Some bugs corrected for windows. Also, when
   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");    mle=-1 a template is output in file "or"mypar.txt with the design
   m[nrl] += NR_END;    of the covariance matrix to be input.
   m[nrl] -= ncl;  
     Revision 1.89  2003/06/24 12:30:52  brouard
   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;    (Module): Some bugs corrected for windows. Also, when
   return m;    mle=-1 a template is output in file "or"mypar.txt with the design
 }    of the covariance matrix to be input.
   
 /*************************free matrix ************************/    Revision 1.88  2003/06/23 17:54:56  brouard
 void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)    * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
 {  
   free((FREE_ARG)(m[nrl]+ncl-NR_END));    Revision 1.87  2003/06/18 12:26:01  brouard
   free((FREE_ARG)(m+nrl-NR_END));    Version 0.96
 }  
     Revision 1.86  2003/06/17 20:04:08  brouard
 /******************* ma3x *******************************/    (Module): Change position of html and gnuplot routines and added
 double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)    routine fileappend.
 {  
   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;    Revision 1.85  2003/06/17 13:12:43  brouard
   double ***m;    * imach.c (Repository): Check when date of death was earlier that
     current date of interview. It may happen when the death was just
   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));    prior to the death. In this case, dh was negative and likelihood
   if (!m) nrerror("allocation failure 1 in matrix()");    was wrong (infinity). We still send an "Error" but patch by
   m += NR_END;    assuming that the date of death was just one stepm after the
   m -= nrl;    interview.
     (Repository): Because some people have very long ID (first column)
   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));    we changed int to long in num[] and we added a new lvector for
   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");    memory allocation. But we also truncated to 8 characters (left
   m[nrl] += NR_END;    truncation)
   m[nrl] -= ncl;    (Repository): No more line truncation errors.
   
   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;    Revision 1.84  2003/06/13 21:44:43  brouard
     * imach.c (Repository): Replace "freqsummary" at a correct
   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));    place. It differs from routine "prevalence" which may be called
   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");    many times. Probs is memory consuming and must be used with
   m[nrl][ncl] += NR_END;    parcimony.
   m[nrl][ncl] -= nll;    Version 0.95a3 (should output exactly the same maximization than 0.8a2)
   for (j=ncl+1; j<=nch; j++)  
     m[nrl][j]=m[nrl][j-1]+nlay;    Revision 1.83  2003/06/10 13:39:11  lievre
      *** empty log message ***
   for (i=nrl+1; i<=nrh; i++) {  
     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;    Revision 1.82  2003/06/05 15:57:20  brouard
     for (j=ncl+1; j<=nch; j++)    Add log in  imach.c and  fullversion number is now printed.
       m[i][j]=m[i][j-1]+nlay;  
   }  */
   return m;  /*
 }     Interpolated Markov Chain
   
 /*************************free ma3x ************************/    Short summary of the programme:
 void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)    
 {    This program computes Healthy Life Expectancies from
   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));    cross-longitudinal data. Cross-longitudinal data consist in: -1- a
   free((FREE_ARG)(m[nrl]+ncl-NR_END));    first survey ("cross") where individuals from different ages are
   free((FREE_ARG)(m+nrl-NR_END));    interviewed on their health status or degree of disability (in the
 }    case of a health survey which is our main interest) -2- at least a
     second wave of interviews ("longitudinal") which measure each change
 /***************** f1dim *************************/    (if any) in individual health status.  Health expectancies are
 extern int ncom;    computed from the time spent in each health state according to a
 extern double *pcom,*xicom;    model. More health states you consider, more time is necessary to reach the
 extern double (*nrfunc)(double []);    Maximum Likelihood of the parameters involved in the model.  The
      simplest model is the multinomial logistic model where pij is the
 double f1dim(double x)    probability to be observed in state j at the second wave
 {    conditional to be observed in state i at the first wave. Therefore
   int j;    the model is: log(pij/pii)= aij + bij*age+ cij*sex + etc , where
   double f;    'age' is age and 'sex' is a covariate. If you want to have a more
   double *xt;    complex model than "constant and age", you should modify the program
      where the markup *Covariates have to be included here again* invites
   xt=vector(1,ncom);    you to do it.  More covariates you add, slower the
   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j];    convergence.
   f=(*nrfunc)(xt);  
   free_vector(xt,1,ncom);    The advantage of this computer programme, compared to a simple
   return f;    multinomial logistic model, is clear when the delay between waves is not
 }    identical for each individual. Also, if a individual missed an
     intermediate interview, the information is lost, but taken into
 /*****************brent *************************/    account using an interpolation or extrapolation.  
 double brent(double ax, double bx, double cx, double (*f)(double), double tol,  double *xmin)  
 {    hPijx is the probability to be observed in state i at age x+h
   int iter;    conditional to the observed state i at age x. The delay 'h' can be
   double a,b,d,etemp;    split into an exact number (nh*stepm) of unobserved intermediate
   double fu,fv,fw,fx;    states. This elementary transition (by month, quarter,
   double ftemp;    semester or year) is modelled as a multinomial logistic.  The hPx
   double p,q,r,tol1,tol2,u,v,w,x,xm;    matrix is simply the matrix product of nh*stepm elementary matrices
   double e=0.0;    and the contribution of each individual to the likelihood is simply
      hPijx.
   a=(ax < cx ? ax : cx);  
   b=(ax > cx ? ax : cx);    Also this programme outputs the covariance matrix of the parameters but also
   x=w=v=bx;    of the life expectancies. It also computes the period (stable) prevalence. 
   fw=fv=fx=(*f)(x);    
   for (iter=1;iter<=ITMAX;iter++) {    Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
     xm=0.5*(a+b);             Institut national d'études démographiques, Paris.
     tol2=2.0*(tol1=tol*fabs(x)+ZEPS);    This software have been partly granted by Euro-REVES, a concerted action
     /*          if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/    from the European Union.
     printf(".");fflush(stdout);    It is copyrighted identically to a GNU software product, ie programme and
 #ifdef DEBUG    software can be distributed freely for non commercial use. Latest version
     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);    can be accessed at http://euroreves.ined.fr/imach .
     /*          if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */  
 #endif    Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
     if (fabs(x-xm) <= (tol2-0.5*(b-a))){    or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
       *xmin=x;    
       return fx;    **********************************************************************/
     }  /*
     ftemp=fu;    main
     if (fabs(e) > tol1) {    read parameterfile
       r=(x-w)*(fx-fv);    read datafile
       q=(x-v)*(fx-fw);    concatwav
       p=(x-v)*q-(x-w)*r;    freqsummary
       q=2.0*(q-r);    if (mle >= 1)
       if (q > 0.0) p = -p;      mlikeli
       q=fabs(q);    print results files
       etemp=e;    if mle==1 
       e=d;       computes hessian
       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x))    read end of parameter file: agemin, agemax, bage, fage, estepm
         d=CGOLD*(e=(x >= xm ? a-x : b-x));        begin-prev-date,...
       else {    open gnuplot file
         d=p/q;    open html file
         u=x+d;    period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
         if (u-a < tol2 || b-u < tol2)     for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
           d=SIGN(tol1,xm-x);                                    | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
       }      freexexit2 possible for memory heap.
     } else {  
       d=CGOLD*(e=(x >= xm ? a-x : b-x));    h Pij x                         | pij_nom  ficrestpij
     }     # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d));         1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
     fu=(*f)(u);         1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
     if (fu <= fx) {  
       if (u >= x) a=x; else b=x;         1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
       SHFT(v,w,x,u)         1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
         SHFT(fv,fw,fx,fu)    variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
         } else {     Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
           if (u < x) a=u; else b=u;     Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
           if (fu <= fw || w == x) {  
             v=w;    forecasting if prevfcast==1 prevforecast call prevalence()
             w=u;    health expectancies
             fv=fw;    Variance-covariance of DFLE
             fw=fu;    prevalence()
           } else if (fu <= fv || v == x || v == w) {     movingaverage()
             v=u;    varevsij() 
             fv=fu;    if popbased==1 varevsij(,popbased)
           }    total life expectancies
         }    Variance of period (stable) prevalence
   }   end
   nrerror("Too many iterations in brent");  */
   *xmin=x;  
   return fx;  
 }  
    
 /****************** mnbrak ***********************/  #include <math.h>
   #include <stdio.h>
 void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc,  #include <stdlib.h>
             double (*func)(double))  #include <string.h>
 {  #include <unistd.h>
   double ulim,u,r,q, dum;  
   double fu;  #include <limits.h>
    #include <sys/types.h>
   *fa=(*func)(*ax);  #include <sys/stat.h>
   *fb=(*func)(*bx);  #include <errno.h>
   if (*fb > *fa) {  extern int errno;
     SHFT(dum,*ax,*bx,dum)  
       SHFT(dum,*fb,*fa,dum)  #ifdef LINUX
       }  #include <time.h>
   *cx=(*bx)+GOLD*(*bx-*ax);  #include "timeval.h"
   *fc=(*func)(*cx);  #else
   while (*fb > *fc) {  #include <sys/time.h>
     r=(*bx-*ax)*(*fb-*fc);  #endif
     q=(*bx-*cx)*(*fb-*fa);  
     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/  #ifdef GSL
       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r));  #include <gsl/gsl_errno.h>
     ulim=(*bx)+GLIMIT*(*cx-*bx);  #include <gsl/gsl_multimin.h>
     if ((*bx-u)*(u-*cx) > 0.0) {  #endif
       fu=(*func)(u);  
     } else if ((*cx-u)*(u-ulim) > 0.0) {  /* #include <libintl.h> */
       fu=(*func)(u);  /* #define _(String) gettext (String) */
       if (fu < *fc) {  
         SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx))  #define MAXLINE 1024 /* Was 256. Overflow with 312 with 2 states and 4 covariates. Should be ok */
           SHFT(*fb,*fc,fu,(*func)(u))  
           }  #define GNUPLOTPROGRAM "gnuplot"
     } else if ((u-ulim)*(ulim-*cx) >= 0.0) {  /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
       u=ulim;  #define FILENAMELENGTH 132
       fu=(*func)(u);  
     } else {  #define GLOCK_ERROR_NOPATH              -1      /* empty path */
       u=(*cx)+GOLD*(*cx-*bx);  #define GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
       fu=(*func)(u);  
     }  #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
     SHFT(*ax,*bx,*cx,u)  #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
       SHFT(*fa,*fb,*fc,fu)  
       }  #define NINTERVMAX 8
 }  #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
   #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
 /*************** linmin ************************/  #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
   #define codtabm(h,k)  1 & (h-1) >> (k-1) ;
 int ncom;  #define MAXN 20000
 double *pcom,*xicom;  #define YEARM 12. /**< Number of months per year */
 double (*nrfunc)(double []);  #define AGESUP 130
    #define AGEBASE 40
 void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []))  #define AGEGOMP 10. /**< Minimal age for Gompertz adjustment */
 {  #ifdef UNIX
   double brent(double ax, double bx, double cx,  #define DIRSEPARATOR '/'
                double (*f)(double), double tol, double *xmin);  #define CHARSEPARATOR "/"
   double f1dim(double x);  #define ODIRSEPARATOR '\\'
   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb,  #else
               double *fc, double (*func)(double));  #define DIRSEPARATOR '\\'
   int j;  #define CHARSEPARATOR "\\"
   double xx,xmin,bx,ax;  #define ODIRSEPARATOR '/'
   double fx,fb,fa;  #endif
    
   ncom=n;  /* $Id$ */
   pcom=vector(1,n);  /* $State$ */
   xicom=vector(1,n);  
   nrfunc=func;  char version[]="Imach version 0.98nT, January 2014,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121)";
   for (j=1;j<=n;j++) {  char fullversion[]="$Revision$ $Date$"; 
     pcom[j]=p[j];  char strstart[80];
     xicom[j]=xi[j];  char optionfilext[10], optionfilefiname[FILENAMELENGTH];
   }  int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
   ax=0.0;  int nvar=0, nforce=0; /* Number of variables, number of forces */
   xx=1.0;  /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
   mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin);  int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
 #ifdef DEBUG  int cptcovs=0; /**< cptcovs number of simple covariates V2+V1 =2 */
   printf("retour brent fret=%.12e xmin=%.12e\n",*fret,xmin);  int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
 #endif  int cptcovprodnoage=0; /**< Number of covariate products without age */   
   for (j=1;j<=n;j++) {  int cptcoveff=0; /* Total number of covariates to vary for printing results */
     xi[j] *= xmin;  int cptcov=0; /* Working variable */
     p[j] += xi[j];  int npar=NPARMAX;
   }  int nlstate=2; /* Number of live states */
   free_vector(xicom,1,n);  int ndeath=1; /* Number of dead states */
   free_vector(pcom,1,n);  int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
 }  int popbased=0;
   
 /*************** powell ************************/  int *wav; /* Number of waves for this individuual 0 is possible */
 void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret,  int maxwav=0; /* Maxim number of waves */
             double (*func)(double []))  int jmin=0, jmax=0; /* min, max spacing between 2 waves */
 {  int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
   void linmin(double p[], double xi[], int n, double *fret,  int gipmx=0, gsw=0; /* Global variables on the number of contributions 
               double (*func)(double []));                     to the likelihood and the sum of weights (done by funcone)*/
   int i,ibig,j;  int mle=1, weightopt=0;
   double del,t,*pt,*ptt,*xit;  int **mw; /* mw[mi][i] is number of the mi wave for this individual */
   double fp,fptt;  int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
   double *xits;  int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
   pt=vector(1,n);             * wave mi and wave mi+1 is not an exact multiple of stepm. */
   ptt=vector(1,n);  double jmean=1; /* Mean space between 2 waves */
   xit=vector(1,n);  double **matprod2(); /* test */
   xits=vector(1,n);  double **oldm, **newm, **savm; /* Working pointers to matrices */
   *fret=(*func)(p);  double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
   for (j=1;j<=n;j++) pt[j]=p[j];  /*FILE *fic ; */ /* Used in readdata only */
   for (*iter=1;;++(*iter)) {  FILE *ficpar, *ficparo,*ficres, *ficresp, *ficrespl, *ficrespij, *ficrest,*ficresf,*ficrespop;
     fp=(*fret);  FILE *ficlog, *ficrespow;
     ibig=0;  int globpr=0; /* Global variable for printing or not */
     del=0.0;  double fretone; /* Only one call to likelihood */
     printf("\nPowell iter=%d -2*LL=%.12f",*iter,*fret);  long ipmx=0; /* Number of contributions */
     for (i=1;i<=n;i++)  double sw; /* Sum of weights */
       printf(" %d %.12f",i, p[i]);  char filerespow[FILENAMELENGTH];
     printf("\n");  char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
     for (i=1;i<=n;i++) {  FILE *ficresilk;
       for (j=1;j<=n;j++) xit[j]=xi[j][i];  FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
       fptt=(*fret);  FILE *ficresprobmorprev;
 #ifdef DEBUG  FILE *fichtm, *fichtmcov; /* Html File */
       printf("fret=%lf \n",*fret);  FILE *ficreseij;
 #endif  char filerese[FILENAMELENGTH];
       printf("%d",i);fflush(stdout);  FILE *ficresstdeij;
       linmin(p,xit,n,fret,func);  char fileresstde[FILENAMELENGTH];
       if (fabs(fptt-(*fret)) > del) {  FILE *ficrescveij;
         del=fabs(fptt-(*fret));  char filerescve[FILENAMELENGTH];
         ibig=i;  FILE  *ficresvij;
       }  char fileresv[FILENAMELENGTH];
 #ifdef DEBUG  FILE  *ficresvpl;
       printf("%d %.12e",i,(*fret));  char fileresvpl[FILENAMELENGTH];
       for (j=1;j<=n;j++) {  char title[MAXLINE];
         xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);  char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH];
         printf(" x(%d)=%.12e",j,xit[j]);  char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
       }  char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
       for(j=1;j<=n;j++)  char command[FILENAMELENGTH];
         printf(" p=%.12e",p[j]);  int  outcmd=0;
       printf("\n");  
 #endif  char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
     }  
     if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) {  char filelog[FILENAMELENGTH]; /* Log file */
 #ifdef DEBUG  char filerest[FILENAMELENGTH];
       int k[2],l;  char fileregp[FILENAMELENGTH];
       k[0]=1;  char popfile[FILENAMELENGTH];
       k[1]=-1;  
       printf("Max: %.12e",(*func)(p));  char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
       for (j=1;j<=n;j++)  
         printf(" %.12e",p[j]);  struct timeval start_time, end_time, curr_time, last_time, forecast_time;
       printf("\n");  struct timezone tzp;
       for(l=0;l<=1;l++) {  extern int gettimeofday();
         for (j=1;j<=n;j++) {  struct tm tmg, tm, tmf, *gmtime(), *localtime();
           ptt[j]=p[j]+(p[j]-pt[j])*k[l];  long time_value;
           printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);  extern long time();
         }  char strcurr[80], strfor[80];
         printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));  
       }  char *endptr;
 #endif  long lval;
   double dval;
   
       free_vector(xit,1,n);  #define NR_END 1
       free_vector(xits,1,n);  #define FREE_ARG char*
       free_vector(ptt,1,n);  #define FTOL 1.0e-10
       free_vector(pt,1,n);  
       return;  #define NRANSI 
     }  #define ITMAX 200 
     if (*iter == ITMAX) nrerror("powell exceeding maximum iterations.");  
     for (j=1;j<=n;j++) {  #define TOL 2.0e-4 
       ptt[j]=2.0*p[j]-pt[j];  
       xit[j]=p[j]-pt[j];  #define CGOLD 0.3819660 
       pt[j]=p[j];  #define ZEPS 1.0e-10 
     }  #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
     fptt=(*func)(ptt);  
     if (fptt < fp) {  #define GOLD 1.618034 
       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt);  #define GLIMIT 100.0 
       if (t < 0.0) {  #define TINY 1.0e-20 
         linmin(p,xit,n,fret,func);  
         for (j=1;j<=n;j++) {  static double maxarg1,maxarg2;
           xi[j][ibig]=xi[j][n];  #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
           xi[j][n]=xit[j];  #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
         }    
 #ifdef DEBUG  #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
         printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);  #define rint(a) floor(a+0.5)
         for(j=1;j<=n;j++)  
           printf(" %.12e",xit[j]);  static double sqrarg;
         printf("\n");  #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
 #endif  #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
       }  int agegomp= AGEGOMP;
     }  
   }  int imx; 
 }  int stepm=1;
   /* Stepm, step in month: minimum step interpolation*/
 /**** Prevalence limit ****************/  
   int estepm;
 double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int ij)  /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
 {  
   /* Computes the prevalence limit in each live state at age x by left multiplying the unit  int m,nb;
      matrix by transitions matrix until convergence is reached */  long *num;
   int firstpass=0, lastpass=4,*cod, *ncodemax, *Tage,*cens;
   int i, ii,j,k;  double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
   double min, max, maxmin, maxmax,sumnew=0.;  double **pmmij, ***probs;
   double **matprod2();  double *ageexmed,*agecens;
   double **out, cov[NCOVMAX], **pmij();  double dateintmean=0;
   double **newm;  
   double agefin, delaymax=50 ; /* Max number of years to converge */  double *weight;
   int **s; /* Status */
   for (ii=1;ii<=nlstate+ndeath;ii++)  double *agedc;
     for (j=1;j<=nlstate+ndeath;j++){  double  **covar; /**< covar[j,i], value of jth covariate for individual i,
       oldm[ii][j]=(ii==j ? 1.0 : 0.0);                    * covar=matrix(0,NCOVMAX,1,n); 
     }                    * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2]; */
   double  idx; 
    cov[1]=1.;  int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
    int *Ndum; /** Freq of modality (tricode */
  /* Even if hstepm = 1, at least one multiplication by the unit matrix */  int **codtab; /**< codtab=imatrix(1,100,1,10); */
   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){  int **Tvard, *Tprod, cptcovprod, *Tvaraff;
     newm=savm;  double *lsurv, *lpop, *tpop;
     /* Covariates have to be included here again */  
      cov[2]=agefin;  double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
    double ftolhess; /**< Tolerance for computing hessian */
       for (k=1; k<=cptcovn;k++) {  
         cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]];  /**************** split *************************/
         /*printf("ij=%d Tvar[k]=%d nbcode=%d cov=%lf\n",ij, Tvar[k],nbcode[Tvar[k]][codtab[ij][Tvar[k]]],cov[2+k]);*/  static  int split( char *path, char *dirc, char *name, char *ext, char *finame )
       }  {
       for (k=1; k<=cptcovage;k++)    /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
         cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];       the name of the file (name), its extension only (ext) and its first part of the name (finame)
       for (k=1; k<=cptcovprod;k++)    */ 
         cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];    char  *ss;                            /* pointer */
     int   l1, l2;                         /* length counters */
       /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/  
       /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/    l1 = strlen(path );                   /* length of path */
     if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);    ss= strrchr( path, DIRSEPARATOR );            /* find last / */
     if ( ss == NULL ) {                   /* no directory, so determine current directory */
     savm=oldm;      strcpy( name, path );               /* we got the fullname name because no directory */
     oldm=newm;      /*if(strrchr(path, ODIRSEPARATOR )==NULL)
     maxmax=0.;        printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
     for(j=1;j<=nlstate;j++){      /* get current working directory */
       min=1.;      /*    extern  char* getcwd ( char *buf , int len);*/
       max=0.;      if ( getcwd( dirc, FILENAME_MAX ) == NULL ) {
       for(i=1; i<=nlstate; i++) {        return( GLOCK_ERROR_GETCWD );
         sumnew=0;      }
         for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];      /* got dirc from getcwd*/
         prlim[i][j]= newm[i][j]/(1-sumnew);      printf(" DIRC = %s \n",dirc);
         max=FMAX(max,prlim[i][j]);    } else {                              /* strip direcotry from path */
         min=FMIN(min,prlim[i][j]);      ss++;                               /* after this, the filename */
       }      l2 = strlen( ss );                  /* length of filename */
       maxmin=max-min;      if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
       maxmax=FMAX(maxmax,maxmin);      strcpy( name, ss );         /* save file name */
     }      strncpy( dirc, path, l1 - l2 );     /* now the directory */
     if(maxmax < ftolpl){      dirc[l1-l2] = 0;                    /* add zero */
       return prlim;      printf(" DIRC2 = %s \n",dirc);
     }    }
   }    /* We add a separator at the end of dirc if not exists */
 }    l1 = strlen( dirc );                  /* length of directory */
     if( dirc[l1-1] != DIRSEPARATOR ){
 /*************** transition probabilities ***************/      dirc[l1] =  DIRSEPARATOR;
       dirc[l1+1] = 0; 
 double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )      printf(" DIRC3 = %s \n",dirc);
 {    }
   double s1, s2;    ss = strrchr( name, '.' );            /* find last / */
   /*double t34;*/    if (ss >0){
   int i,j,j1, nc, ii, jj;      ss++;
       strcpy(ext,ss);                     /* save extension */
     for(i=1; i<= nlstate; i++){      l1= strlen( name);
     for(j=1; j<i;j++){      l2= strlen(ss)+1;
       for (nc=1, s2=0.;nc <=ncovmodel; nc++){      strncpy( finame, name, l1-l2);
         /*s2 += param[i][j][nc]*cov[nc];*/      finame[l1-l2]= 0;
         s2 += x[(i-1)*nlstate*ncovmodel+(j-1)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];    }
         /*printf("Int j<i s1=%.17e, s2=%.17e\n",s1,s2);*/  
       }    return( 0 );                          /* we're done */
       ps[i][j]=s2;  }
       /*printf("s1=%.17e, s2=%.17e\n",s1,s2);*/  
     }  
     for(j=i+1; j<=nlstate+ndeath;j++){  /******************************************/
       for (nc=1, s2=0.;nc <=ncovmodel; nc++){  
         s2 += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];  void replace_back_to_slash(char *s, char*t)
         /*printf("Int j>i s1=%.17e, s2=%.17e %lx %lx\n",s1,s2,s1,s2);*/  {
       }    int i;
       ps[i][j]=(s2);    int lg=0;
     }    i=0;
   }    lg=strlen(t);
     /*ps[3][2]=1;*/    for(i=0; i<= lg; i++) {
       (s[i] = t[i]);
   for(i=1; i<= nlstate; i++){      if (t[i]== '\\') s[i]='/';
      s1=0;    }
     for(j=1; j<i; j++)  }
       s1+=exp(ps[i][j]);  
     for(j=i+1; j<=nlstate+ndeath; j++)  char *trimbb(char *out, char *in)
       s1+=exp(ps[i][j]);  { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
     ps[i][i]=1./(s1+1.);    char *s;
     for(j=1; j<i; j++)    s=out;
       ps[i][j]= exp(ps[i][j])*ps[i][i];    while (*in != '\0'){
     for(j=i+1; j<=nlstate+ndeath; j++)      while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
       ps[i][j]= exp(ps[i][j])*ps[i][i];        in++;
     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */      }
   } /* end i */      *out++ = *in++;
     }
   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){    *out='\0';
     for(jj=1; jj<= nlstate+ndeath; jj++){    return s;
       ps[ii][jj]=0;  }
       ps[ii][ii]=1;  
     }  char *cutl(char *blocc, char *alocc, char *in, char occ)
   }  {
     /* cuts string in into blocc and alocc where blocc ends before first occurence of char 'occ' 
        and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
   /*   for(ii=1; ii<= nlstate+ndeath; ii++){       gives blocc="abcdef2ghi" and alocc="j".
     for(jj=1; jj<= nlstate+ndeath; jj++){       If occ is not found blocc is null and alocc is equal to in. Returns blocc
      printf("%lf ",ps[ii][jj]);    */
    }    char *s, *t, *bl;
     printf("\n ");    t=in;s=in;
     }    while ((*in != occ) && (*in != '\0')){
     printf("\n ");printf("%lf ",cov[2]);*/      *alocc++ = *in++;
 /*    }
   for(i=1; i<= npar; i++) printf("%f ",x[i]);    if( *in == occ){
   goto end;*/      *(alocc)='\0';
     return ps;      s=++in;
 }    }
    
 /**************** Product of 2 matrices ******************/    if (s == t) {/* occ not found */
       *(alocc-(in-s))='\0';
 double **matprod2(double **out, double **in,long nrl, long nrh, long ncl, long nch, long ncolol, long ncoloh, double **b)      in=s;
 {    }
   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times    while ( *in != '\0'){
      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */      *blocc++ = *in++;
   /* in, b, out are matrice of pointers which should have been initialized    }
      before: only the contents of out is modified. The function returns  
      a pointer to pointers identical to out */    *blocc='\0';
   long i, j, k;    return t;
   for(i=nrl; i<= nrh; i++)  }
     for(k=ncolol; k<=ncoloh; k++)  char *cutv(char *blocc, char *alocc, char *in, char occ)
       for(j=ncl,out[i][k]=0.; j<=nch; j++)  {
         out[i][k] +=in[i][j]*b[j][k];    /* cuts string in into blocc and alocc where blocc ends before last occurence of char 'occ' 
        and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
   return out;       gives blocc="abcdef2ghi" and alocc="j".
 }       If occ is not found blocc is null and alocc is equal to in. Returns alocc
     */
     char *s, *t;
 /************* Higher Matrix Product ***************/    t=in;s=in;
     while (*in != '\0'){
 double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij )      while( *in == occ){
 {        *blocc++ = *in++;
   /* Computes the transition matrix starting at age 'age' over 'nhstepm*hstepm*stepm' month        s=in;
      duration (i.e. until      }
      age (in years)  age+nhstepm*stepm/12) by multiplying nhstepm*hstepm matrices.      *blocc++ = *in++;
      Output is stored in matrix po[i][j][h] for h every 'hstepm' step    }
      (typically every 2 years instead of every month which is too big).    if (s == t) /* occ not found */
      Model is determined by parameters x and covariates have to be      *(blocc-(in-s))='\0';
      included manually here.    else
       *(blocc-(in-s)-1)='\0';
      */    in=s;
     while ( *in != '\0'){
   int i, j, d, h, k;      *alocc++ = *in++;
   double **out, cov[NCOVMAX];    }
   double **newm;  
     *alocc='\0';
   /* Hstepm could be zero and should return the unit matrix */    return s;
   for (i=1;i<=nlstate+ndeath;i++)  }
     for (j=1;j<=nlstate+ndeath;j++){  
       oldm[i][j]=(i==j ? 1.0 : 0.0);  int nbocc(char *s, char occ)
       po[i][j][0]=(i==j ? 1.0 : 0.0);  {
     }    int i,j=0;
   /* Even if hstepm = 1, at least one multiplication by the unit matrix */    int lg=20;
   for(h=1; h <=nhstepm; h++){    i=0;
     for(d=1; d <=hstepm; d++){    lg=strlen(s);
       newm=savm;    for(i=0; i<= lg; i++) {
       /* Covariates have to be included here again */    if  (s[i] == occ ) j++;
       cov[1]=1.;    }
       cov[2]=age+((h-1)*hstepm + (d-1))*stepm/YEARM;    return j;
       for (k=1; k<=cptcovn;k++) cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]];  }
       for (k=1; k<=cptcovage;k++)  
         cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];  /* void cutv(char *u,char *v, char*t, char occ) */
       for (k=1; k<=cptcovprod;k++)  /* { */
         cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];  /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
   /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
   /*      gives u="abcdef2ghi" and v="j" *\/ */
       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/  /*   int i,lg,j,p=0; */
       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/  /*   i=0; */
       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,  /*   lg=strlen(t); */
                    pmij(pmmij,cov,ncovmodel,x,nlstate));  /*   for(j=0; j<=lg-1; j++) { */
       savm=oldm;  /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
       oldm=newm;  /*   } */
     }  
     for(i=1; i<=nlstate+ndeath; i++)  /*   for(j=0; j<p; j++) { */
       for(j=1;j<=nlstate+ndeath;j++) {  /*     (u[j] = t[j]); */
         po[i][j][h]=newm[i][j];  /*   } */
         /*printf("i=%d j=%d h=%d po[i][j][h]=%f ",i,j,h,po[i][j][h]);  /*      u[p]='\0'; */
          */  
       }  /*    for(j=0; j<= lg; j++) { */
   } /* end h */  /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
   return po;  /*   } */
 }  /* } */
   
   /********************** nrerror ********************/
 /*************** log-likelihood *************/  
 double func( double *x)  void nrerror(char error_text[])
 {  {
   int i, ii, j, k, mi, d, kk;    fprintf(stderr,"ERREUR ...\n");
   double l, ll[NLSTATEMAX], cov[NCOVMAX];    fprintf(stderr,"%s\n",error_text);
   double **out;    exit(EXIT_FAILURE);
   double sw; /* Sum of weights */  }
   double lli; /* Individual log likelihood */  /*********************** vector *******************/
   long ipmx;  double *vector(int nl, int nh)
   /*extern weight */  {
   /* We are differentiating ll according to initial status */    double *v;
   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/    v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
   /*for(i=1;i<imx;i++)    if (!v) nrerror("allocation failure in vector");
     printf(" %d\n",s[4][i]);    return v-nl+NR_END;
   */  }
   cov[1]=1.;  
   /************************ free vector ******************/
   for(k=1; k<=nlstate; k++) ll[k]=0.;  void free_vector(double*v, int nl, int nh)
   for (i=1,ipmx=0, sw=0.; i<=imx; i++){  {
     for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];    free((FREE_ARG)(v+nl-NR_END));
     for(mi=1; mi<= wav[i]-1; mi++){  }
       for (ii=1;ii<=nlstate+ndeath;ii++)  
         for (j=1;j<=nlstate+ndeath;j++) oldm[ii][j]=(ii==j ? 1.0 : 0.0);  /************************ivector *******************************/
       for(d=0; d<dh[mi][i]; d++){  int *ivector(long nl,long nh)
         newm=savm;  {
         cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;    int *v;
         for (kk=1; kk<=cptcovage;kk++) {    v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
           cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];    if (!v) nrerror("allocation failure in ivector");
         }    return v-nl+NR_END;
          }
         out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,  
                      1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));  /******************free ivector **************************/
         savm=oldm;  void free_ivector(int *v, long nl, long nh)
         oldm=newm;  {
            free((FREE_ARG)(v+nl-NR_END));
          }
       } /* end mult */  
        /************************lvector *******************************/
       lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);  long *lvector(long nl,long nh)
       /* printf(" %f ",out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/  {
       ipmx +=1;    long *v;
       sw += weight[i];    v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;    if (!v) nrerror("allocation failure in ivector");
     } /* end of wave */    return v-nl+NR_END;
   } /* end of individual */  }
   
   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];  /******************free lvector **************************/
   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */  void free_lvector(long *v, long nl, long nh)
   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */  {
   return -l;    free((FREE_ARG)(v+nl-NR_END));
 }  }
   
   /******************* imatrix *******************************/
 /*********** Maximum Likelihood Estimation ***************/  int **imatrix(long nrl, long nrh, long ncl, long nch) 
        /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
 void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))  { 
 {    long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
   int i,j, iter;    int **m; 
   double **xi,*delti;    
   double fret;    /* allocate pointers to rows */ 
   xi=matrix(1,npar,1,npar);    m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
   for (i=1;i<=npar;i++)    if (!m) nrerror("allocation failure 1 in matrix()"); 
     for (j=1;j<=npar;j++)    m += NR_END; 
       xi[i][j]=(i==j ? 1.0 : 0.0);    m -= nrl; 
   printf("Powell\n");    
   powell(p,xi,npar,ftol,&iter,&fret,func);    
     /* allocate rows and set pointers to them */ 
    printf("\n#Number of iterations = %d, -2 Log likelihood = %.12f\n",iter,func(p));    m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
   fprintf(ficres,"#Number of iterations = %d, -2 Log likelihood = %.12f ",iter,func(p));    if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
     m[nrl] += NR_END; 
 }    m[nrl] -= ncl; 
     
 /**** Computes Hessian and covariance matrix ***/    for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
 void hesscov(double **matcov, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))    
 {    /* return pointer to array of pointers to rows */ 
   double  **a,**y,*x,pd;    return m; 
   double **hess;  } 
   int i, j,jk;  
   int *indx;  /****************** free_imatrix *************************/
   void free_imatrix(m,nrl,nrh,ncl,nch)
   double hessii(double p[], double delta, int theta, double delti[]);        int **m;
   double hessij(double p[], double delti[], int i, int j);        long nch,ncl,nrh,nrl; 
   void lubksb(double **a, int npar, int *indx, double b[]) ;       /* free an int matrix allocated by imatrix() */ 
   void ludcmp(double **a, int npar, int *indx, double *d) ;  { 
     free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
   hess=matrix(1,npar,1,npar);    free((FREE_ARG) (m+nrl-NR_END)); 
   } 
   printf("\nCalculation of the hessian matrix. Wait...\n");  
   for (i=1;i<=npar;i++){  /******************* matrix *******************************/
     printf("%d",i);fflush(stdout);  double **matrix(long nrl, long nrh, long ncl, long nch)
     hess[i][i]=hessii(p,ftolhess,i,delti);  {
     /*printf(" %f ",p[i]);*/    long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
     /*printf(" %lf ",hess[i][i]);*/    double **m;
   }  
      m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
   for (i=1;i<=npar;i++) {    if (!m) nrerror("allocation failure 1 in matrix()");
     for (j=1;j<=npar;j++)  {    m += NR_END;
       if (j>i) {    m -= nrl;
         printf(".%d%d",i,j);fflush(stdout);  
         hess[i][j]=hessij(p,delti,i,j);    m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
         hess[j][i]=hess[i][j];        if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
         /*printf(" %lf ",hess[i][j]);*/    m[nrl] += NR_END;
       }    m[nrl] -= ncl;
     }  
   }    for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
   printf("\n");    return m;
     /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");  m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
    that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
   a=matrix(1,npar,1,npar);     */
   y=matrix(1,npar,1,npar);  }
   x=vector(1,npar);  
   indx=ivector(1,npar);  /*************************free matrix ************************/
   for (i=1;i<=npar;i++)  void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];  {
   ludcmp(a,npar,indx,&pd);    free((FREE_ARG)(m[nrl]+ncl-NR_END));
     free((FREE_ARG)(m+nrl-NR_END));
   for (j=1;j<=npar;j++) {  }
     for (i=1;i<=npar;i++) x[i]=0;  
     x[j]=1;  /******************* ma3x *******************************/
     lubksb(a,npar,indx,x);  double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
     for (i=1;i<=npar;i++){  {
       matcov[i][j]=x[i];    long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
     }    double ***m;
   }  
     m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
   printf("\n#Hessian matrix#\n");    if (!m) nrerror("allocation failure 1 in matrix()");
   for (i=1;i<=npar;i++) {    m += NR_END;
     for (j=1;j<=npar;j++) {    m -= nrl;
       printf("%.3e ",hess[i][j]);  
     }    m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
     printf("\n");    if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
   }    m[nrl] += NR_END;
     m[nrl] -= ncl;
   /* Recompute Inverse */  
   for (i=1;i<=npar;i++)    for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
     for (j=1;j<=npar;j++) a[i][j]=matcov[i][j];  
   ludcmp(a,npar,indx,&pd);    m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
     if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
   /*  printf("\n#Hessian matrix recomputed#\n");    m[nrl][ncl] += NR_END;
     m[nrl][ncl] -= nll;
   for (j=1;j<=npar;j++) {    for (j=ncl+1; j<=nch; j++) 
     for (i=1;i<=npar;i++) x[i]=0;      m[nrl][j]=m[nrl][j-1]+nlay;
     x[j]=1;    
     lubksb(a,npar,indx,x);    for (i=nrl+1; i<=nrh; i++) {
     for (i=1;i<=npar;i++){      m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
       y[i][j]=x[i];      for (j=ncl+1; j<=nch; j++) 
       printf("%.3e ",y[i][j]);        m[i][j]=m[i][j-1]+nlay;
     }    }
     printf("\n");    return m; 
   }    /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
   */             &(m[i][j][k]) <=> *((*(m+i) + j)+k)
     */
   free_matrix(a,1,npar,1,npar);  }
   free_matrix(y,1,npar,1,npar);  
   free_vector(x,1,npar);  /*************************free ma3x ************************/
   free_ivector(indx,1,npar);  void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
   free_matrix(hess,1,npar,1,npar);  {
     free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
     free((FREE_ARG)(m[nrl]+ncl-NR_END));
 }    free((FREE_ARG)(m+nrl-NR_END));
   }
 /*************** hessian matrix ****************/  
 double hessii( double x[], double delta, int theta, double delti[])  /*************** function subdirf ***********/
 {  char *subdirf(char fileres[])
   int i;  {
   int l=1, lmax=20;    /* Caution optionfilefiname is hidden */
   double k1,k2;    strcpy(tmpout,optionfilefiname);
   double p2[NPARMAX+1];    strcat(tmpout,"/"); /* Add to the right */
   double res;    strcat(tmpout,fileres);
   double delt, delts, nkhi=10.,nkhif=1., khi=1.e-4;    return tmpout;
   double fx;  }
   int k=0,kmax=10;  
   double l1;  /*************** function subdirf2 ***********/
   char *subdirf2(char fileres[], char *preop)
   fx=func(x);  {
   for (i=1;i<=npar;i++) p2[i]=x[i];    
   for(l=0 ; l <=lmax; l++){    /* Caution optionfilefiname is hidden */
     l1=pow(10,l);    strcpy(tmpout,optionfilefiname);
     delts=delt;    strcat(tmpout,"/");
     for(k=1 ; k <kmax; k=k+1){    strcat(tmpout,preop);
       delt = delta*(l1*k);    strcat(tmpout,fileres);
       p2[theta]=x[theta] +delt;    return tmpout;
       k1=func(p2)-fx;  }
       p2[theta]=x[theta]-delt;  
       k2=func(p2)-fx;  /*************** function subdirf3 ***********/
       /*res= (k1-2.0*fx+k2)/delt/delt; */  char *subdirf3(char fileres[], char *preop, char *preop2)
       res= (k1+k2)/delt/delt/2.; /* Divided by because L and not 2*L */  {
          
 #ifdef DEBUG    /* Caution optionfilefiname is hidden */
       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);    strcpy(tmpout,optionfilefiname);
 #endif    strcat(tmpout,"/");
       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */    strcat(tmpout,preop);
       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){    strcat(tmpout,preop2);
         k=kmax;    strcat(tmpout,fileres);
       }    return tmpout;
       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */  }
         k=kmax; l=lmax*10.;  
       }  /***************** f1dim *************************/
       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  extern int ncom; 
         delts=delt;  extern double *pcom,*xicom;
       }  extern double (*nrfunc)(double []); 
     }   
   }  double f1dim(double x) 
   delti[theta]=delts;  { 
   return res;    int j; 
      double f;
 }    double *xt; 
    
 double hessij( double x[], double delti[], int thetai,int thetaj)    xt=vector(1,ncom); 
 {    for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
   int i;    f=(*nrfunc)(xt); 
   int l=1, l1, lmax=20;    free_vector(xt,1,ncom); 
   double k1,k2,k3,k4,res,fx;    return f; 
   double p2[NPARMAX+1];  } 
   int k;  
   /*****************brent *************************/
   fx=func(x);  double brent(double ax, double bx, double cx, double (*f)(double), double tol,  double *xmin) 
   for (k=1; k<=2; k++) {  { 
     for (i=1;i<=npar;i++) p2[i]=x[i];    int iter; 
     p2[thetai]=x[thetai]+delti[thetai]/k;    double a,b,d,etemp;
     p2[thetaj]=x[thetaj]+delti[thetaj]/k;    double fu,fv,fw,fx;
     k1=func(p2)-fx;    double ftemp;
      double p,q,r,tol1,tol2,u,v,w,x,xm; 
     p2[thetai]=x[thetai]+delti[thetai]/k;    double e=0.0; 
     p2[thetaj]=x[thetaj]-delti[thetaj]/k;   
     k2=func(p2)-fx;    a=(ax < cx ? ax : cx); 
      b=(ax > cx ? ax : cx); 
     p2[thetai]=x[thetai]-delti[thetai]/k;    x=w=v=bx; 
     p2[thetaj]=x[thetaj]+delti[thetaj]/k;    fw=fv=fx=(*f)(x); 
     k3=func(p2)-fx;    for (iter=1;iter<=ITMAX;iter++) { 
        xm=0.5*(a+b); 
     p2[thetai]=x[thetai]-delti[thetai]/k;      tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
     p2[thetaj]=x[thetaj]-delti[thetaj]/k;      /*          if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
     k4=func(p2)-fx;      printf(".");fflush(stdout);
     res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /* Because of L not 2*L */      fprintf(ficlog,".");fflush(ficlog);
 #ifdef DEBUG  #ifdef DEBUG
     printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);      printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
 #endif      fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
   }      /*          if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
   return res;  #endif
 }      if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
         *xmin=x; 
 /************** Inverse of matrix **************/        return fx; 
 void ludcmp(double **a, int n, int *indx, double *d)      } 
 {      ftemp=fu;
   int i,imax,j,k;      if (fabs(e) > tol1) { 
   double big,dum,sum,temp;        r=(x-w)*(fx-fv); 
   double *vv;        q=(x-v)*(fx-fw); 
          p=(x-v)*q-(x-w)*r; 
   vv=vector(1,n);        q=2.0*(q-r); 
   *d=1.0;        if (q > 0.0) p = -p; 
   for (i=1;i<=n;i++) {        q=fabs(q); 
     big=0.0;        etemp=e; 
     for (j=1;j<=n;j++)        e=d; 
       if ((temp=fabs(a[i][j])) > big) big=temp;        if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
     if (big == 0.0) nrerror("Singular matrix in routine ludcmp");          d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
     vv[i]=1.0/big;        else { 
   }          d=p/q; 
   for (j=1;j<=n;j++) {          u=x+d; 
     for (i=1;i<j;i++) {          if (u-a < tol2 || b-u < tol2) 
       sum=a[i][j];            d=SIGN(tol1,xm-x); 
       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j];        } 
       a[i][j]=sum;      } else { 
     }        d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
     big=0.0;      } 
     for (i=j;i<=n;i++) {      u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
       sum=a[i][j];      fu=(*f)(u); 
       for (k=1;k<j;k++)      if (fu <= fx) { 
         sum -= a[i][k]*a[k][j];        if (u >= x) a=x; else b=x; 
       a[i][j]=sum;        SHFT(v,w,x,u) 
       if ( (dum=vv[i]*fabs(sum)) >= big) {          SHFT(fv,fw,fx,fu) 
         big=dum;          } else { 
         imax=i;            if (u < x) a=u; else b=u; 
       }            if (fu <= fw || w == x) { 
     }              v=w; 
     if (j != imax) {              w=u; 
       for (k=1;k<=n;k++) {              fv=fw; 
         dum=a[imax][k];              fw=fu; 
         a[imax][k]=a[j][k];            } else if (fu <= fv || v == x || v == w) { 
         a[j][k]=dum;              v=u; 
       }              fv=fu; 
       *d = -(*d);            } 
       vv[imax]=vv[j];          } 
     }    } 
     indx[j]=imax;    nrerror("Too many iterations in brent"); 
     if (a[j][j] == 0.0) a[j][j]=TINY;    *xmin=x; 
     if (j != n) {    return fx; 
       dum=1.0/(a[j][j]);  } 
       for (i=j+1;i<=n;i++) a[i][j] *= dum;  
     }  /****************** mnbrak ***********************/
   }  
   free_vector(vv,1,n);  /* Doesn't work */  void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
 ;              double (*func)(double)) 
 }  { 
     double ulim,u,r,q, dum;
 void lubksb(double **a, int n, int *indx, double b[])    double fu; 
 {   
   int i,ii=0,ip,j;    *fa=(*func)(*ax); 
   double sum;    *fb=(*func)(*bx); 
      if (*fb > *fa) { 
   for (i=1;i<=n;i++) {      SHFT(dum,*ax,*bx,dum) 
     ip=indx[i];        SHFT(dum,*fb,*fa,dum) 
     sum=b[ip];        } 
     b[ip]=b[i];    *cx=(*bx)+GOLD*(*bx-*ax); 
     if (ii)    *fc=(*func)(*cx); 
       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j];    while (*fb > *fc) { 
     else if (sum) ii=i;      r=(*bx-*ax)*(*fb-*fc); 
     b[i]=sum;      q=(*bx-*cx)*(*fb-*fa); 
   }      u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
   for (i=n;i>=1;i--) {        (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); 
     sum=b[i];      ulim=(*bx)+GLIMIT*(*cx-*bx); 
     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j];      if ((*bx-u)*(u-*cx) > 0.0) { 
     b[i]=sum/a[i][i];        fu=(*func)(u); 
   }      } else if ((*cx-u)*(u-ulim) > 0.0) { 
 }        fu=(*func)(u); 
         if (fu < *fc) { 
 /************ Frequencies ********************/          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
 void  freqsummary(char fileres[], int agemin, int agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax)            SHFT(*fb,*fc,fu,(*func)(u)) 
 {  /* Some frequencies */            } 
        } else if ((u-ulim)*(ulim-*cx) >= 0.0) { 
   int i, m, jk, k1, i1, j1, bool, z1,z2,j;        u=ulim; 
   double ***freq; /* Frequencies */        fu=(*func)(u); 
   double *pp;      } else { 
   double pos;        u=(*cx)+GOLD*(*cx-*bx); 
   FILE *ficresp;        fu=(*func)(u); 
   char fileresp[FILENAMELENGTH];      } 
       SHFT(*ax,*bx,*cx,u) 
   pp=vector(1,nlstate);        SHFT(*fa,*fb,*fc,fu) 
  probs= ma3x(1,130 ,1,8, 1,8);        } 
   strcpy(fileresp,"p");  } 
   strcat(fileresp,fileres);  
   if((ficresp=fopen(fileresp,"w"))==NULL) {  /*************** linmin ************************/
     printf("Problem with prevalence resultfile: %s\n", fileresp);  
     exit(0);  int ncom; 
   }  double *pcom,*xicom;
   freq= ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,agemin,agemax+3);  double (*nrfunc)(double []); 
   j1=0;   
   void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
   j=cptcoveff;  { 
   if (cptcovn<1) {j=1;ncodemax[1]=1;}    double brent(double ax, double bx, double cx, 
                  double (*f)(double), double tol, double *xmin); 
   for(k1=1; k1<=j;k1++){    double f1dim(double x); 
    for(i1=1; i1<=ncodemax[k1];i1++){    void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
        j1++;                double *fc, double (*func)(double)); 
        /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);    int j; 
          scanf("%d", i);*/    double xx,xmin,bx,ax; 
         for (i=-1; i<=nlstate+ndeath; i++)      double fx,fb,fa;
          for (jk=-1; jk<=nlstate+ndeath; jk++)     
            for(m=agemin; m <= agemax+3; m++)    ncom=n; 
              freq[i][jk][m]=0;    pcom=vector(1,n); 
            xicom=vector(1,n); 
        for (i=1; i<=imx; i++) {    nrfunc=func; 
          bool=1;    for (j=1;j<=n;j++) { 
          if  (cptcovn>0) {      pcom[j]=p[j]; 
            for (z1=1; z1<=cptcoveff; z1++)      xicom[j]=xi[j]; 
              if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtab[j1][z1]])    } 
                bool=0;    ax=0.0; 
          }    xx=1.0; 
           if (bool==1) {    mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim); 
            for(m=fprev; m<=lprev; m++){    *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); 
              if(agev[m][i]==0) agev[m][i]=agemax+1;  #ifdef DEBUG
              if(agev[m][i]==1) agev[m][i]=agemax+2;    printf("retour brent fret=%.12e xmin=%.12e\n",*fret,xmin);
              freq[s[m][i]][s[m+1][i]][(int)agev[m][i]] += weight[i];    fprintf(ficlog,"retour brent fret=%.12e xmin=%.12e\n",*fret,xmin);
              freq[s[m][i]][s[m+1][i]][(int) agemax+3] += weight[i];  #endif
            }    for (j=1;j<=n;j++) { 
          }      xi[j] *= xmin; 
        }      p[j] += xi[j]; 
         if  (cptcovn>0) {    } 
          fprintf(ficresp, "\n#********** Variable ");    free_vector(xicom,1,n); 
          for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);    free_vector(pcom,1,n); 
        fprintf(ficresp, "**********\n#");  } 
         }  
        for(i=1; i<=nlstate;i++)  char *asc_diff_time(long time_sec, char ascdiff[])
          fprintf(ficresp, " Age Prev(%d) N(%d) N",i,i);  {
        fprintf(ficresp, "\n");    long sec_left, days, hours, minutes;
            days = (time_sec) / (60*60*24);
   for(i=(int)agemin; i <= (int)agemax+3; i++){    sec_left = (time_sec) % (60*60*24);
     if(i==(int)agemax+3)    hours = (sec_left) / (60*60) ;
       printf("Total");    sec_left = (sec_left) %(60*60);
     else    minutes = (sec_left) /60;
       printf("Age %d", i);    sec_left = (sec_left) % (60);
     for(jk=1; jk <=nlstate ; jk++){    sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
       for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)    return ascdiff;
         pp[jk] += freq[jk][m][i];  }
     }  
     for(jk=1; jk <=nlstate ; jk++){  /*************** powell ************************/
       for(m=-1, pos=0; m <=0 ; m++)  void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
         pos += freq[jk][m][i];              double (*func)(double [])) 
       if(pp[jk]>=1.e-10)  { 
         printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);    void linmin(double p[], double xi[], int n, double *fret, 
       else                double (*func)(double [])); 
         printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);    int i,ibig,j; 
     }    double del,t,*pt,*ptt,*xit;
     double fp,fptt;
      for(jk=1; jk <=nlstate ; jk++){    double *xits;
       for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)    int niterf, itmp;
         pp[jk] += freq[jk][m][i];  
      }    pt=vector(1,n); 
     ptt=vector(1,n); 
     for(jk=1,pos=0; jk <=nlstate ; jk++)    xit=vector(1,n); 
       pos += pp[jk];    xits=vector(1,n); 
     for(jk=1; jk <=nlstate ; jk++){    *fret=(*func)(p); 
       if(pos>=1.e-5)    for (j=1;j<=n;j++) pt[j]=p[j]; 
         printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);    for (*iter=1;;++(*iter)) { 
       else      fp=(*fret); 
         printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);      ibig=0; 
       if( i <= (int) agemax){      del=0.0; 
         if(pos>=1.e-5){      last_time=curr_time;
           fprintf(ficresp," %d %.5f %.0f %.0f",i,pp[jk]/pos, pp[jk],pos);      (void) gettimeofday(&curr_time,&tzp);
           probs[i][jk][j1]= pp[jk]/pos;      printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, curr_time.tv_sec-last_time.tv_sec, curr_time.tv_sec-start_time.tv_sec);fflush(stdout);
           /*printf("\ni=%d jk=%d j1=%d %.5f %.0f %.0f %f",i,jk,j1,pp[jk]/pos, pp[jk],pos,probs[i][jk][j1]);*/      fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, curr_time.tv_sec-last_time.tv_sec, curr_time.tv_sec-start_time.tv_sec); fflush(ficlog);
         }  /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tv_sec-start_time.tv_sec); */
       else     for (i=1;i<=n;i++) {
           fprintf(ficresp," %d NaNq %.0f %.0f",i,pp[jk],pos);        printf(" %d %.12f",i, p[i]);
       }        fprintf(ficlog," %d %.12lf",i, p[i]);
     }        fprintf(ficrespow," %.12lf", p[i]);
     for(jk=-1; jk <=nlstate+ndeath; jk++)      }
       for(m=-1; m <=nlstate+ndeath; m++)      printf("\n");
         if(freq[jk][m][i] !=0 ) printf(" %d%d=%.0f",jk,m,freq[jk][m][i]);      fprintf(ficlog,"\n");
     if(i <= (int) agemax)      fprintf(ficrespow,"\n");fflush(ficrespow);
       fprintf(ficresp,"\n");      if(*iter <=3){
     printf("\n");        tm = *localtime(&curr_time.tv_sec);
     }        strcpy(strcurr,asctime(&tm));
     }  /*       asctime_r(&tm,strcurr); */
  }        forecast_time=curr_time; 
          itmp = strlen(strcurr);
   fclose(ficresp);        if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
   free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath,(int) agemin,(int) agemax+3);          strcurr[itmp-1]='\0';
   free_vector(pp,1,nlstate);        printf("\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,curr_time.tv_sec-last_time.tv_sec);
         fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,curr_time.tv_sec-last_time.tv_sec);
 }  /* End of Freq */        for(niterf=10;niterf<=30;niterf+=10){
           forecast_time.tv_sec=curr_time.tv_sec+(niterf-*iter)*(curr_time.tv_sec-last_time.tv_sec);
 /************* Waves Concatenation ***************/          tmf = *localtime(&forecast_time.tv_sec);
   /*      asctime_r(&tmf,strfor); */
 void  concatwav(int wav[], int **dh, int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)          strcpy(strfor,asctime(&tmf));
 {          itmp = strlen(strfor);
   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.          if(strfor[itmp-1]=='\n')
      Death is a valid wave (if date is known).          strfor[itmp-1]='\0';
      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i          printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(forecast_time.tv_sec-curr_time.tv_sec,tmpout),strfor,strcurr);
      dh[m][i] of dh[mw[mi][i][i] is the delay between two effective waves m=mw[mi][i]          fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(forecast_time.tv_sec-curr_time.tv_sec,tmpout),strfor,strcurr);
      and mw[mi+1][i]. dh depends on stepm.        }
      */      }
       for (i=1;i<=n;i++) { 
   int i, mi, m;        for (j=1;j<=n;j++) xit[j]=xi[j][i]; 
   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;        fptt=(*fret); 
      double sum=0., jmean=0.;*/  #ifdef DEBUG
         printf("fret=%lf \n",*fret);
   int j, k=0,jk, ju, jl;        fprintf(ficlog,"fret=%lf \n",*fret);
   double sum=0.;  #endif
   jmin=1e+5;        printf("%d",i);fflush(stdout);
   jmax=-1;        fprintf(ficlog,"%d",i);fflush(ficlog);
   jmean=0.;        linmin(p,xit,n,fret,func); 
   for(i=1; i<=imx; i++){        if (fabs(fptt-(*fret)) > del) { 
     mi=0;          del=fabs(fptt-(*fret)); 
     m=firstpass;          ibig=i; 
     while(s[m][i] <= nlstate){        } 
       if(s[m][i]>=1)  #ifdef DEBUG
         mw[++mi][i]=m;        printf("%d %.12e",i,(*fret));
       if(m >=lastpass)        fprintf(ficlog,"%d %.12e",i,(*fret));
         break;        for (j=1;j<=n;j++) {
       else          xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
         m++;          printf(" x(%d)=%.12e",j,xit[j]);
     }/* end while */          fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
     if (s[m][i] > nlstate){        }
       mi++;     /* Death is another wave */        for(j=1;j<=n;j++) {
       /* if(mi==0)  never been interviewed correctly before death */          printf(" p=%.12e",p[j]);
          /* Only death is a correct wave */          fprintf(ficlog," p=%.12e",p[j]);
       mw[mi][i]=m;        }
     }        printf("\n");
         fprintf(ficlog,"\n");
     wav[i]=mi;  #endif
     if(mi==0)      } 
       printf("Warning, no any valid information for:%d line=%d\n",num[i],i);      if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) {
   }  #ifdef DEBUG
         int k[2],l;
   for(i=1; i<=imx; i++){        k[0]=1;
     for(mi=1; mi<wav[i];mi++){        k[1]=-1;
       if (stepm <=0)        printf("Max: %.12e",(*func)(p));
         dh[mi][i]=1;        fprintf(ficlog,"Max: %.12e",(*func)(p));
       else{        for (j=1;j<=n;j++) {
         if (s[mw[mi+1][i]][i] > nlstate) {          printf(" %.12e",p[j]);
           if (agedc[i] < 2*AGESUP) {          fprintf(ficlog," %.12e",p[j]);
           j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12);        }
           if(j==0) j=1;  /* Survives at least one month after exam */        printf("\n");
           k=k+1;        fprintf(ficlog,"\n");
           if (j >= jmax) jmax=j;        for(l=0;l<=1;l++) {
           if (j <= jmin) jmin=j;          for (j=1;j<=n;j++) {
           sum=sum+j;            ptt[j]=p[j]+(p[j]-pt[j])*k[l];
           /* if (j<10) printf("j=%d num=%d ",j,i); */            printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
           }            fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
         }          }
         else{          printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
           j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));          fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
           k=k+1;        }
           if (j >= jmax) jmax=j;  #endif
           else if (j <= jmin)jmin=j;  
           /*   if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */  
           sum=sum+j;        free_vector(xit,1,n); 
         }        free_vector(xits,1,n); 
         jk= j/stepm;        free_vector(ptt,1,n); 
         jl= j -jk*stepm;        free_vector(pt,1,n); 
         ju= j -(jk+1)*stepm;        return; 
         if(jl <= -ju)      } 
           dh[mi][i]=jk;      if (*iter == ITMAX) nrerror("powell exceeding maximum iterations."); 
         else      for (j=1;j<=n;j++) { 
           dh[mi][i]=jk+1;        ptt[j]=2.0*p[j]-pt[j]; 
         if(dh[mi][i]==0)        xit[j]=p[j]-pt[j]; 
           dh[mi][i]=1; /* At least one step */        pt[j]=p[j]; 
       }      } 
     }      fptt=(*func)(ptt); 
   }      if (fptt < fp) { 
   jmean=sum/k;        t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); 
   printf("Delay (in months) between two waves Min=%d Max=%d Mean=%f\n\n ",jmin, jmax,jmean);        if (t < 0.0) { 
  }          linmin(p,xit,n,fret,func); 
 /*********** Tricode ****************************/          for (j=1;j<=n;j++) { 
 void tricode(int *Tvar, int **nbcode, int imx)            xi[j][ibig]=xi[j][n]; 
 {            xi[j][n]=xit[j]; 
   int Ndum[20],ij=1, k, j, i;          }
   int cptcode=0;  #ifdef DEBUG
   cptcoveff=0;          printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
            fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
   for (k=0; k<19; k++) Ndum[k]=0;          for(j=1;j<=n;j++){
   for (k=1; k<=7; k++) ncodemax[k]=0;            printf(" %.12e",xit[j]);
             fprintf(ficlog," %.12e",xit[j]);
   for (j=1; j<=(cptcovn+2*cptcovprod); j++) {          }
     for (i=1; i<=imx; i++) {          printf("\n");
       ij=(int)(covar[Tvar[j]][i]);          fprintf(ficlog,"\n");
       Ndum[ij]++;  #endif
       /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/        }
       if (ij > cptcode) cptcode=ij;      } 
     }    } 
   } 
     for (i=0; i<=cptcode; i++) {  
       if(Ndum[i]!=0) ncodemax[j]++;  /**** Prevalence limit (stable or period prevalence)  ****************/
     }  
     ij=1;  double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int ij)
   {
     /* Computes the prevalence limit in each live state at age x by left multiplying the unit
     for (i=1; i<=ncodemax[j]; i++) {       matrix by transitions matrix until convergence is reached */
       for (k=0; k<=19; k++) {  
         if (Ndum[k] != 0) {    int i, ii,j,k;
           nbcode[Tvar[j]][ij]=k;    double min, max, maxmin, maxmax,sumnew=0.;
           ij++;    /* double **matprod2(); */ /* test */
         }    double **out, cov[NCOVMAX+1], **pmij();
         if (ij > ncodemax[j]) break;    double **newm;
       }      double agefin, delaymax=50 ; /* Max number of years to converge */
     }  
   }      for (ii=1;ii<=nlstate+ndeath;ii++)
       for (j=1;j<=nlstate+ndeath;j++){
  for (k=0; k<19; k++) Ndum[k]=0;        oldm[ii][j]=(ii==j ? 1.0 : 0.0);
       }
  for (i=1; i<=ncovmodel-2; i++) {  
       ij=Tvar[i];     cov[1]=1.;
       Ndum[ij]++;   
     }   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
     for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
  ij=1;      newm=savm;
  for (i=1; i<=10; i++) {      /* Covariates have to be included here again */
    if((Ndum[i]!=0) && (i<=ncov)){      cov[2]=agefin;
      Tvaraff[ij]=i;      
      ij++;      for (k=1; k<=cptcovn;k++) {
    }        cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]];
  }        /*printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtab[%d][Tvar[%d]]=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtab[ij][Tvar[k]]],cov[2+k], ij, k, codtab[ij][Tvar[k]]);*/
        }
     cptcoveff=ij-1;      /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
 }      /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
       /*   cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]] * nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]]; */
 /*********** Health Expectancies ****************/      
       /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
 void evsij(char fileres[], double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int ij)      /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
 {      /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
   /* Health expectancies */      /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
   int i, j, nhstepm, hstepm, h;      /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
   double age, agelim,hf;      out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
   double ***p3mat;      
        savm=oldm;
   fprintf(ficreseij,"# Health expectancies\n");      oldm=newm;
   fprintf(ficreseij,"# Age");      maxmax=0.;
   for(i=1; i<=nlstate;i++)      for(j=1;j<=nlstate;j++){
     for(j=1; j<=nlstate;j++)        min=1.;
       fprintf(ficreseij," %1d-%1d",i,j);        max=0.;
   fprintf(ficreseij,"\n");        for(i=1; i<=nlstate; i++) {
           sumnew=0;
   hstepm=1*YEARM; /*  Every j years of age (in month) */          for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */          prlim[i][j]= newm[i][j]/(1-sumnew);
           /*printf(" prevalim i=%d, j=%d, prmlim[%d][%d]=%f, agefin=%d \n", i, j, i, j, prlim[i][j],(int)agefin);*/
   agelim=AGESUP;          max=FMAX(max,prlim[i][j]);
   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */          min=FMIN(min,prlim[i][j]);
     /* nhstepm age range expressed in number of stepm */        }
     nhstepm=(int) rint((agelim-age)*YEARM/stepm);        maxmin=max-min;
     /* Typically if 20 years = 20*12/6=40 stepm */        maxmax=FMAX(maxmax,maxmin);
     if (stepm >= YEARM) hstepm=1;      }
     nhstepm = nhstepm/hstepm;/* Expressed in hstepm, typically 40/4=10 */      if(maxmax < ftolpl){
     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);        return prlim;
     /* Computed by stepm unit matrices, product of hstepm matrices, stored      }
        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */    }
     hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, ij);    }
   
   /*************** transition probabilities ***************/ 
     for(i=1; i<=nlstate;i++)  
       for(j=1; j<=nlstate;j++)  double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
         for (h=0, eij[i][j][(int)age]=0; h<=nhstepm; h++){  {
           eij[i][j][(int)age] +=p3mat[i][j][h];    /* According to parameters values stored in x and the covariate's values stored in cov,
         }       computes the probability to be observed in state j being in state i by appying the
           model to the ncovmodel covariates (including constant and age).
     hf=1;       lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
     if (stepm >= YEARM) hf=stepm/YEARM;       and, according on how parameters are entered, the position of the coefficient xij(nc) of the
     fprintf(ficreseij,"%.0f",age );       ncth covariate in the global vector x is given by the formula:
     for(i=1; i<=nlstate;i++)       j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
       for(j=1; j<=nlstate;j++){       j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
         fprintf(ficreseij," %.4f", hf*eij[i][j][(int)age]);       Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
       }       sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
     fprintf(ficreseij,"\n");       Outputs ps[i][j] the probability to be observed in j being in j according to
     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);       the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
   }    */
 }    double s1, lnpijopii;
     /*double t34;*/
 /************ Variance ******************/    int i,j,j1, nc, ii, jj;
 void varevsij(char fileres[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij)  
 {      for(i=1; i<= nlstate; i++){
   /* Variance of health expectancies */        for(j=1; j<i;j++){
   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/          for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
   double **newm;            /*lnpijopii += param[i][j][nc]*cov[nc];*/
   double **dnewm,**doldm;            lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
   int i, j, nhstepm, hstepm, h;  /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
   int k, cptcode;          }
   double *xp;          ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
   double **gp, **gm;  /*      printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
   double ***gradg, ***trgradg;        }
   double ***p3mat;        for(j=i+1; j<=nlstate+ndeath;j++){
   double age,agelim;          for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
   int theta;            /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
             lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
    fprintf(ficresvij,"# Covariances of life expectancies\n");  /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
   fprintf(ficresvij,"# Age");          }
   for(i=1; i<=nlstate;i++)          ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
     for(j=1; j<=nlstate;j++)        }
       fprintf(ficresvij," Cov(e%1d, e%1d)",i,j);      }
   fprintf(ficresvij,"\n");      
       for(i=1; i<= nlstate; i++){
   xp=vector(1,npar);        s1=0;
   dnewm=matrix(1,nlstate,1,npar);        for(j=1; j<i; j++){
   doldm=matrix(1,nlstate,1,nlstate);          s1+=exp(ps[i][j]); /* In fact sums pij/pii */
            /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
   hstepm=1*YEARM; /* Every year of age */        }
   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */        for(j=i+1; j<=nlstate+ndeath; j++){
   agelim = AGESUP;          s1+=exp(ps[i][j]); /* In fact sums pij/pii */
   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */          /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */        }
     if (stepm >= YEARM) hstepm=1;        /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */        ps[i][i]=1./(s1+1.);
     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);        /* Computing other pijs */
     gradg=ma3x(0,nhstepm,1,npar,1,nlstate);        for(j=1; j<i; j++)
     gp=matrix(0,nhstepm,1,nlstate);          ps[i][j]= exp(ps[i][j])*ps[i][i];
     gm=matrix(0,nhstepm,1,nlstate);        for(j=i+1; j<=nlstate+ndeath; j++)
           ps[i][j]= exp(ps[i][j])*ps[i][i];
     for(theta=1; theta <=npar; theta++){        /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
       for(i=1; i<=npar; i++){ /* Computes gradient */      } /* end i */
         xp[i] = x[i] + (i==theta ?delti[theta]:0);      
       }      for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
       hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);          for(jj=1; jj<= nlstate+ndeath; jj++){
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);          ps[ii][jj]=0;
           ps[ii][ii]=1;
       if (popbased==1) {        }
         for(i=1; i<=nlstate;i++)      }
           prlim[i][i]=probs[(int)age][i][ij];      
       }      
            /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
       for(j=1; j<= nlstate; j++){      /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
         for(h=0; h<=nhstepm; h++){      /*  printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
           for(i=1, gp[h][j]=0.;i<=nlstate;i++)      /*   } */
             gp[h][j] += prlim[i][i]*p3mat[i][j][h];      /*   printf("\n "); */
         }      /* } */
       }      /* printf("\n ");printf("%lf ",cov[2]);*/
          /*
       for(i=1; i<=npar; i++) /* Computes gradient */        for(i=1; i<= npar; i++) printf("%f ",x[i]);
         xp[i] = x[i] - (i==theta ?delti[theta]:0);        goto end;*/
       hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);        return ps;
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);  }
   
       if (popbased==1) {  /**************** Product of 2 matrices ******************/
         for(i=1; i<=nlstate;i++)  
           prlim[i][i]=probs[(int)age][i][ij];  double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
       }  {
     /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
       for(j=1; j<= nlstate; j++){       b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
         for(h=0; h<=nhstepm; h++){    /* in, b, out are matrice of pointers which should have been initialized 
           for(i=1, gm[h][j]=0.;i<=nlstate;i++)       before: only the contents of out is modified. The function returns
             gm[h][j] += prlim[i][i]*p3mat[i][j][h];       a pointer to pointers identical to out */
         }    int i, j, k;
       }    for(i=nrl; i<= nrh; i++)
       for(k=ncolol; k<=ncoloh; k++){
       for(j=1; j<= nlstate; j++)        out[i][k]=0.;
         for(h=0; h<=nhstepm; h++){        for(j=ncl; j<=nch; j++)
           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];          out[i][k] +=in[i][j]*b[j][k];
         }      }
     } /* End theta */    return out;
   }
     trgradg =ma3x(0,nhstepm,1,nlstate,1,npar);  
   
     for(h=0; h<=nhstepm; h++)  /************* Higher Matrix Product ***************/
       for(j=1; j<=nlstate;j++)  
         for(theta=1; theta <=npar; theta++)  double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij )
           trgradg[h][j][theta]=gradg[h][theta][j];  {
     /* Computes the transition matrix starting at age 'age' over 
     for(i=1;i<=nlstate;i++)       'nhstepm*hstepm*stepm' months (i.e. until
       for(j=1;j<=nlstate;j++)       age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
         vareij[i][j][(int)age] =0.;       nhstepm*hstepm matrices. 
     for(h=0;h<=nhstepm;h++){       Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
       for(k=0;k<=nhstepm;k++){       (typically every 2 years instead of every month which is too big 
         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);       for the memory).
         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);       Model is determined by parameters x and covariates have to be 
         for(i=1;i<=nlstate;i++)       included manually here. 
           for(j=1;j<=nlstate;j++)  
             vareij[i][j][(int)age] += doldm[i][j];       */
       }  
     }    int i, j, d, h, k;
     h=1;    double **out, cov[NCOVMAX+1];
     if (stepm >= YEARM) h=stepm/YEARM;    double **newm;
     fprintf(ficresvij,"%.0f ",age );  
     for(i=1; i<=nlstate;i++)    /* Hstepm could be zero and should return the unit matrix */
       for(j=1; j<=nlstate;j++){    for (i=1;i<=nlstate+ndeath;i++)
         fprintf(ficresvij," %.4f", h*vareij[i][j][(int)age]);      for (j=1;j<=nlstate+ndeath;j++){
       }        oldm[i][j]=(i==j ? 1.0 : 0.0);
     fprintf(ficresvij,"\n");        po[i][j][0]=(i==j ? 1.0 : 0.0);
     free_matrix(gp,0,nhstepm,1,nlstate);      }
     free_matrix(gm,0,nhstepm,1,nlstate);    /* Even if hstepm = 1, at least one multiplication by the unit matrix */
     free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);    for(h=1; h <=nhstepm; h++){
     free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);      for(d=1; d <=hstepm; d++){
     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);        newm=savm;
   } /* End age */        /* Covariates have to be included here again */
          cov[1]=1.;
   free_vector(xp,1,npar);        cov[2]=age+((h-1)*hstepm + (d-1))*stepm/YEARM;
   free_matrix(doldm,1,nlstate,1,npar);        for (k=1; k<=cptcovn;k++) 
   free_matrix(dnewm,1,nlstate,1,nlstate);          cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]];
         for (k=1; k<=cptcovage;k++)
 }          cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];
         for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
 /************ Variance of prevlim ******************/          cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];
 void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij)  
 {  
   /* Variance of prevalence limit */        /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/        /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
   double **newm;        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
   double **dnewm,**doldm;                     pmij(pmmij,cov,ncovmodel,x,nlstate));
   int i, j, nhstepm, hstepm;        savm=oldm;
   int k, cptcode;        oldm=newm;
   double *xp;      }
   double *gp, *gm;      for(i=1; i<=nlstate+ndeath; i++)
   double **gradg, **trgradg;        for(j=1;j<=nlstate+ndeath;j++) {
   double age,agelim;          po[i][j][h]=newm[i][j];
   int theta;          /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
            }
   fprintf(ficresvpl,"# Standard deviation of prevalences limit\n");      /*printf("h=%d ",h);*/
   fprintf(ficresvpl,"# Age");    } /* end h */
   for(i=1; i<=nlstate;i++)  /*     printf("\n H=%d \n",h); */
       fprintf(ficresvpl," %1d-%1d",i,i);    return po;
   fprintf(ficresvpl,"\n");  }
   
   xp=vector(1,npar);  
   dnewm=matrix(1,nlstate,1,npar);  /*************** log-likelihood *************/
   doldm=matrix(1,nlstate,1,nlstate);  double func( double *x)
    {
   hstepm=1*YEARM; /* Every year of age */    int i, ii, j, k, mi, d, kk;
   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */    double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
   agelim = AGESUP;    double **out;
   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */    double sw; /* Sum of weights */
     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */    double lli; /* Individual log likelihood */
     if (stepm >= YEARM) hstepm=1;    int s1, s2;
     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */    double bbh, survp;
     gradg=matrix(1,npar,1,nlstate);    long ipmx;
     gp=vector(1,nlstate);    /*extern weight */
     gm=vector(1,nlstate);    /* We are differentiating ll according to initial status */
     /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
     for(theta=1; theta <=npar; theta++){    /*for(i=1;i<imx;i++) 
       for(i=1; i<=npar; i++){ /* Computes gradient */      printf(" %d\n",s[4][i]);
         xp[i] = x[i] + (i==theta ?delti[theta]:0);    */
       }    cov[1]=1.;
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);  
       for(i=1;i<=nlstate;i++)    for(k=1; k<=nlstate; k++) ll[k]=0.;
         gp[i] = prlim[i][i];  
        if(mle==1){
       for(i=1; i<=npar; i++) /* Computes gradient */      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
         xp[i] = x[i] - (i==theta ?delti[theta]:0);        /* Computes the values of the ncovmodel covariates of the model
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);           depending if the covariates are fixed or variying (age dependent) and stores them in cov[]
       for(i=1;i<=nlstate;i++)           Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
         gm[i] = prlim[i][i];           to be observed in j being in i according to the model.
          */
       for(i=1;i<=nlstate;i++)        for (k=1; k<=cptcovn;k++){ /* Simple and product covariates without age* products */
         gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];          cov[2+k]=covar[Tvar[k]][i];
     } /* End theta */        }
         /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
     trgradg =matrix(1,nlstate,1,npar);           is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
            has been calculated etc */
     for(j=1; j<=nlstate;j++)        for(mi=1; mi<= wav[i]-1; mi++){
       for(theta=1; theta <=npar; theta++)          for (ii=1;ii<=nlstate+ndeath;ii++)
         trgradg[j][theta]=gradg[theta][j];            for (j=1;j<=nlstate+ndeath;j++){
               oldm[ii][j]=(ii==j ? 1.0 : 0.0);
     for(i=1;i<=nlstate;i++)              savm[ii][j]=(ii==j ? 1.0 : 0.0);
       varpl[i][(int)age] =0.;            }
     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);          for(d=0; d<dh[mi][i]; d++){
     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);            newm=savm;
     for(i=1;i<=nlstate;i++)            cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */            for (kk=1; kk<=cptcovage;kk++) {
               cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2]; /* Tage[kk] gives the data-covariate associated with age */
     fprintf(ficresvpl,"%.0f ",age );            }
     for(i=1; i<=nlstate;i++)            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
     fprintf(ficresvpl,"\n");            savm=oldm;
     free_vector(gp,1,nlstate);            oldm=newm;
     free_vector(gm,1,nlstate);          } /* end mult */
     free_matrix(gradg,1,npar,1,nlstate);        
     free_matrix(trgradg,1,nlstate,1,npar);          /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
   } /* End age */          /* But now since version 0.9 we anticipate for bias at large stepm.
            * If stepm is larger than one month (smallest stepm) and if the exact delay 
   free_vector(xp,1,npar);           * (in months) between two waves is not a multiple of stepm, we rounded to 
   free_matrix(doldm,1,nlstate,1,npar);           * the nearest (and in case of equal distance, to the lowest) interval but now
   free_matrix(dnewm,1,nlstate,1,nlstate);           * we keep into memory the bias bh[mi][i] and also the previous matrix product
            * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
 }           * probability in order to take into account the bias as a fraction of the way
            * from savm to out if bh is negative or even beyond if bh is positive. bh varies
 /************ Variance of one-step probabilities  ******************/           * -stepm/2 to stepm/2 .
 void varprob(char fileres[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij)           * For stepm=1 the results are the same as for previous versions of Imach.
 {           * For stepm > 1 the results are less biased than in previous versions. 
   int i, j;           */
   int k=0, cptcode;          s1=s[mw[mi][i]][i];
   double **dnewm,**doldm;          s2=s[mw[mi+1][i]][i];
   double *xp;          bbh=(double)bh[mi][i]/(double)stepm; 
   double *gp, *gm;          /* bias bh is positive if real duration
   double **gradg, **trgradg;           * is higher than the multiple of stepm and negative otherwise.
   double age,agelim, cov[NCOVMAX];           */
   int theta;          /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
   char fileresprob[FILENAMELENGTH];          if( s2 > nlstate){ 
             /* i.e. if s2 is a death state and if the date of death is known 
   strcpy(fileresprob,"prob");               then the contribution to the likelihood is the probability to 
   strcat(fileresprob,fileres);               die between last step unit time and current  step unit time, 
   if((ficresprob=fopen(fileresprob,"w"))==NULL) {               which is also equal to probability to die before dh 
     printf("Problem with resultfile: %s\n", fileresprob);               minus probability to die before dh-stepm . 
   }               In version up to 0.92 likelihood was computed
   printf("Computing variance of one-step probabilities: result on file '%s' \n",fileresprob);          as if date of death was unknown. Death was treated as any other
            health state: the date of the interview describes the actual state
           and not the date of a change in health state. The former idea was
   xp=vector(1,npar);          to consider that at each interview the state was recorded
   dnewm=matrix(1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);          (healthy, disable or death) and IMaCh was corrected; but when we
   doldm=matrix(1,(nlstate+ndeath)*(nlstate+ndeath),1,(nlstate+ndeath)*(nlstate+ndeath));          introduced the exact date of death then we should have modified
            the contribution of an exact death to the likelihood. This new
   cov[1]=1;          contribution is smaller and very dependent of the step unit
   for (age=bage; age<=fage; age ++){          stepm. It is no more the probability to die between last interview
     cov[2]=age;          and month of death but the probability to survive from last
     gradg=matrix(1,npar,1,9);          interview up to one month before death multiplied by the
     trgradg=matrix(1,9,1,npar);          probability to die within a month. Thanks to Chris
     gp=vector(1,(nlstate+ndeath)*(nlstate+ndeath));          Jackson for correcting this bug.  Former versions increased
     gm=vector(1,(nlstate+ndeath)*(nlstate+ndeath));          mortality artificially. The bad side is that we add another loop
              which slows down the processing. The difference can be up to 10%
     for(theta=1; theta <=npar; theta++){          lower mortality.
       for(i=1; i<=npar; i++)            */
         xp[i] = x[i] + (i==theta ?delti[theta]:0);            lli=log(out[s1][s2] - savm[s1][s2]);
        
       pmij(pmmij,cov,ncovmodel,xp,nlstate);  
              } else if  (s2==-2) {
       k=0;            for (j=1,survp=0. ; j<=nlstate; j++) 
       for(i=1; i<= (nlstate+ndeath); i++){              survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
         for(j=1; j<=(nlstate+ndeath);j++){            /*survp += out[s1][j]; */
            k=k+1;            lli= log(survp);
           gp[k]=pmmij[i][j];          }
         }          
       }          else if  (s2==-4) { 
             for (j=3,survp=0. ; j<=nlstate; j++)  
       for(i=1; i<=npar; i++)              survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
         xp[i] = x[i] - (i==theta ?delti[theta]:0);            lli= log(survp); 
              } 
   
       pmij(pmmij,cov,ncovmodel,xp,nlstate);          else if  (s2==-5) { 
       k=0;            for (j=1,survp=0. ; j<=2; j++)  
       for(i=1; i<=(nlstate+ndeath); i++){              survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
         for(j=1; j<=(nlstate+ndeath);j++){            lli= log(survp); 
           k=k+1;          } 
           gm[k]=pmmij[i][j];          
         }          else{
       }            lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                  /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
        for(i=1; i<= (nlstate+ndeath)*(nlstate+ndeath); i++)          } 
            gradg[theta][i]=(gp[i]-gm[i])/2./delti[theta];            /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
     }          /*if(lli ==000.0)*/
           /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
      for(j=1; j<=(nlstate+ndeath)*(nlstate+ndeath);j++)          ipmx +=1;
       for(theta=1; theta <=npar; theta++)          sw += weight[i];
       trgradg[j][theta]=gradg[theta][j];          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
          } /* end of wave */
      matprod2(dnewm,trgradg,1,9,1,npar,1,npar,matcov);      } /* end of individual */
      matprod2(doldm,dnewm,1,9,1,npar,1,9,gradg);    }  else if(mle==2){
       for (i=1,ipmx=0, sw=0.; i<=imx; i++){
      pmij(pmmij,cov,ncovmodel,x,nlstate);        for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
         for(mi=1; mi<= wav[i]-1; mi++){
      k=0;          for (ii=1;ii<=nlstate+ndeath;ii++)
      for(i=1; i<=(nlstate+ndeath); i++){            for (j=1;j<=nlstate+ndeath;j++){
        for(j=1; j<=(nlstate+ndeath);j++){              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
          k=k+1;              savm[ii][j]=(ii==j ? 1.0 : 0.0);
          gm[k]=pmmij[i][j];            }
         }          for(d=0; d<=dh[mi][i]; d++){
      }            newm=savm;
                  cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
      /*printf("\n%d ",(int)age);            for (kk=1; kk<=cptcovage;kk++) {
      for (i=1; i<=(nlstate+ndeath)*(nlstate+ndeath-1);i++){              cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                    }
             out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
        printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
      }*/            savm=oldm;
             oldm=newm;
   fprintf(ficresprob,"\n%d ",(int)age);          } /* end mult */
         
   for (i=1; i<=(nlstate+ndeath)*(nlstate+ndeath-1);i++){          s1=s[mw[mi][i]][i];
     if (i== 2) fprintf(ficresprob,"%.3e %.3e ",gm[i],doldm[i][i]);          s2=s[mw[mi+1][i]][i];
 if (i== 4) fprintf(ficresprob,"%.3e %.3e ",gm[i],doldm[i][i]);          bbh=(double)bh[mi][i]/(double)stepm; 
   }          lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
           ipmx +=1;
     free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));          sw += weight[i];
     free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
     free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);        } /* end of wave */
     free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);      } /* end of individual */
 }    }  else if(mle==3){  /* exponential inter-extrapolation */
  free_vector(xp,1,npar);      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
 fclose(ficresprob);        for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
  exit(0);        for(mi=1; mi<= wav[i]-1; mi++){
 }          for (ii=1;ii<=nlstate+ndeath;ii++)
             for (j=1;j<=nlstate+ndeath;j++){
 /***********************************************/              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
 /**************** Main Program *****************/              savm[ii][j]=(ii==j ? 1.0 : 0.0);
 /***********************************************/            }
           for(d=0; d<dh[mi][i]; d++){
 /*int main(int argc, char *argv[])*/            newm=savm;
 int main()            cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
 {            for (kk=1; kk<=cptcovage;kk++) {
               cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
   int i,j, k, n=MAXN,iter,m,size,cptcode, cptcod;            }
   double agedeb, agefin,hf;            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
   double agemin=1.e20, agemax=-1.e20;                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
             savm=oldm;
   double fret;            oldm=newm;
   double **xi,tmp,delta;          } /* end mult */
         
   double dum; /* Dummy variable */          s1=s[mw[mi][i]][i];
   double ***p3mat;          s2=s[mw[mi+1][i]][i];
   int *indx;          bbh=(double)bh[mi][i]/(double)stepm; 
   char line[MAXLINE], linepar[MAXLINE];          lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
   char title[MAXLINE];          ipmx +=1;
   char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH];          sw += weight[i];
   char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filereso[FILENAMELENGTH], fileresf[FILENAMELENGTH];          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
   char filerest[FILENAMELENGTH];        } /* end of wave */
   char fileregp[FILENAMELENGTH];      } /* end of individual */
   char path[80],pathc[80],pathcd[80],pathtot[80],model[20];    }else if (mle==4){  /* ml=4 no inter-extrapolation */
   int firstobs=1, lastobs=10;      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
   int sdeb, sfin; /* Status at beginning and end */        for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
   int c,  h , cpt,l;        for(mi=1; mi<= wav[i]-1; mi++){
   int ju,jl, mi;          for (ii=1;ii<=nlstate+ndeath;ii++)
   int i1,j1, k1,k2,k3,jk,aa,bb, stepsize, ij;            for (j=1;j<=nlstate+ndeath;j++){
   int jnais,jdc,jint4,jint1,jint2,jint3,**outcome,**adl,*tab;              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
   int mobilav=0, fprevfore=1, lprevfore=1;              savm[ii][j]=(ii==j ? 1.0 : 0.0);
   int hstepm, nhstepm;            }
           for(d=0; d<dh[mi][i]; d++){
   double bage, fage, age, agelim, agebase;            newm=savm;
   double ftolpl=FTOL;            cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
   double **prlim;            for (kk=1; kk<=cptcovage;kk++) {
   double *severity;              cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
   double ***param; /* Matrix of parameters */            }
   double  *p;          
   double **matcov; /* Matrix of covariance */            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
   double ***delti3; /* Scale */                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
   double *delti; /* Scale */            savm=oldm;
   double ***eij, ***vareij;            oldm=newm;
   double **varpl; /* Variances of prevalence limits by age */          } /* end mult */
   double *epj, vepp;        
   double kk1;          s1=s[mw[mi][i]][i];
           s2=s[mw[mi+1][i]][i];
   char version[80]="Imach version 64b, May 2001, INED-EUROREVES ";          if( s2 > nlstate){ 
   char *alph[]={"a","a","b","c","d","e"}, str[4];            lli=log(out[s1][s2] - savm[s1][s2]);
           }else{
             lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
   char z[1]="c", occ;          }
 #include <sys/time.h>          ipmx +=1;
 #include <time.h>          sw += weight[i];
   char stra[80], strb[80], strc[80], strd[80],stre[80],modelsav[80];          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
   /* long total_usecs;  /*      printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
   struct timeval start_time, end_time;        } /* end of wave */
        } /* end of individual */
   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */    }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
       for (i=1,ipmx=0, sw=0.; i<=imx; i++){
         for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
   printf("\nIMACH, Version 0.64b");        for(mi=1; mi<= wav[i]-1; mi++){
   printf("\nEnter the parameter file name: ");          for (ii=1;ii<=nlstate+ndeath;ii++)
             for (j=1;j<=nlstate+ndeath;j++){
 #ifdef windows              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
   scanf("%s",pathtot);              savm[ii][j]=(ii==j ? 1.0 : 0.0);
   getcwd(pathcd, size);            }
   /*cygwin_split_path(pathtot,path,optionfile);          for(d=0; d<dh[mi][i]; d++){
     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/            newm=savm;
   /* cutv(path,optionfile,pathtot,'\\');*/            cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
             for (kk=1; kk<=cptcovage;kk++) {
 split(pathtot, path,optionfile);              cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
   chdir(path);            }
   replace(pathc,path);          
 #endif            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
 #ifdef unix                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
   scanf("%s",optionfile);            savm=oldm;
 #endif            oldm=newm;
           } /* end mult */
 /*-------- arguments in the command line --------*/        
           s1=s[mw[mi][i]][i];
   strcpy(fileres,"r");          s2=s[mw[mi+1][i]][i];
   strcat(fileres, optionfile);          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
           ipmx +=1;
   /*---------arguments file --------*/          sw += weight[i];
           ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
   if((ficpar=fopen(optionfile,"r"))==NULL)    {          /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
     printf("Problem with optionfile %s\n",optionfile);        } /* end of wave */
     goto end;      } /* end of individual */
   }    } /* End of if */
     for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
   strcpy(filereso,"o");    /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
   strcat(filereso,fileres);    l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
   if((ficparo=fopen(filereso,"w"))==NULL) {    return -l;
     printf("Problem with Output resultfile: %s\n", filereso);goto end;  }
   }  
   /*************** log-likelihood *************/
   /* Reads comments: lines beginning with '#' */  double funcone( double *x)
   while((c=getc(ficpar))=='#' && c!= EOF){  {
     ungetc(c,ficpar);    /* Same as likeli but slower because of a lot of printf and if */
     fgets(line, MAXLINE, ficpar);    int i, ii, j, k, mi, d, kk;
     puts(line);    double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
     fputs(line,ficparo);    double **out;
   }    double lli; /* Individual log likelihood */
   ungetc(c,ficpar);    double llt;
     int s1, s2;
   fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncov=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncov, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model);    double bbh, survp;
   printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncov=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncov, nlstate,ndeath, maxwav, mle, weightopt,model);    /*extern weight */
   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncov=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncov,nlstate,ndeath,maxwav, mle, weightopt,model);    /* We are differentiating ll according to initial status */
 while((c=getc(ficpar))=='#' && c!= EOF){    /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
     ungetc(c,ficpar);    /*for(i=1;i<imx;i++) 
     fgets(line, MAXLINE, ficpar);      printf(" %d\n",s[4][i]);
     puts(line);    */
     fputs(line,ficparo);    cov[1]=1.;
   }  
   ungetc(c,ficpar);    for(k=1; k<=nlstate; k++) ll[k]=0.;
    
   fscanf(ficpar,"fprevalence=%d lprevalence=%d pop_based=%d\n",&fprev,&lprev,&popbased);    for (i=1,ipmx=0, sw=0.; i<=imx; i++){
  while((c=getc(ficpar))=='#' && c!= EOF){      for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
     ungetc(c,ficpar);      for(mi=1; mi<= wav[i]-1; mi++){
     fgets(line, MAXLINE, ficpar);        for (ii=1;ii<=nlstate+ndeath;ii++)
     puts(line);          for (j=1;j<=nlstate+ndeath;j++){
     fputs(line,ficparo);            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
   }            savm[ii][j]=(ii==j ? 1.0 : 0.0);
   ungetc(c,ficpar);          }
          for(d=0; d<dh[mi][i]; d++){
   fscanf(ficpar,"fprevalence=%d lprevalence=%d mob_average=%d\n",&fprevfore,&lprevfore,&mobilav);          newm=savm;
            cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
   covar=matrix(0,NCOVMAX,1,n);          for (kk=1; kk<=cptcovage;kk++) {
   cptcovn=0;            cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
   if (strlen(model)>1) cptcovn=nbocc(model,'+')+1;          }
           /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
   ncovmodel=2+cptcovn;          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
   nvar=ncovmodel-1; /* Suppressing age as a basic covariate */                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
            /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
   /* Read guess parameters */          /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
   /* Reads comments: lines beginning with '#' */          savm=oldm;
   while((c=getc(ficpar))=='#' && c!= EOF){          oldm=newm;
     ungetc(c,ficpar);        } /* end mult */
     fgets(line, MAXLINE, ficpar);        
     puts(line);        s1=s[mw[mi][i]][i];
     fputs(line,ficparo);        s2=s[mw[mi+1][i]][i];
   }        bbh=(double)bh[mi][i]/(double)stepm; 
   ungetc(c,ficpar);        /* bias is positive if real duration
           * is higher than the multiple of stepm and negative otherwise.
   param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);         */
     for(i=1; i <=nlstate; i++)        if( s2 > nlstate && (mle <5) ){  /* Jackson */
     for(j=1; j <=nlstate+ndeath-1; j++){          lli=log(out[s1][s2] - savm[s1][s2]);
       fscanf(ficpar,"%1d%1d",&i1,&j1);        } else if  (s2==-2) {
       fprintf(ficparo,"%1d%1d",i1,j1);          for (j=1,survp=0. ; j<=nlstate; j++) 
       printf("%1d%1d",i,j);            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
       for(k=1; k<=ncovmodel;k++){          lli= log(survp);
         fscanf(ficpar," %lf",&param[i][j][k]);        }else if (mle==1){
         printf(" %lf",param[i][j][k]);          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
         fprintf(ficparo," %lf",param[i][j][k]);        } else if(mle==2){
       }          lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
       fscanf(ficpar,"\n");        } else if(mle==3){  /* exponential inter-extrapolation */
       printf("\n");          lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
       fprintf(ficparo,"\n");        } else if (mle==4){  /* mle=4 no inter-extrapolation */
     }          lli=log(out[s1][s2]); /* Original formula */
          } else{  /* mle=0 back to 1 */
     npar= (nlstate+ndeath-1)*nlstate*ncovmodel;          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
           /*lli=log(out[s1][s2]); */ /* Original formula */
   p=param[1][1];        } /* End of if */
          ipmx +=1;
   /* Reads comments: lines beginning with '#' */        sw += weight[i];
   while((c=getc(ficpar))=='#' && c!= EOF){        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
     ungetc(c,ficpar);        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
     fgets(line, MAXLINE, ficpar);        if(globpr){
     puts(line);          fprintf(ficresilk,"%9ld %6d %2d %2d %1d %1d %3d %11.6f %8.4f\
     fputs(line,ficparo);   %11.6f %11.6f %11.6f ", \
   }                  num[i],i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],
   ungetc(c,ficpar);                  2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
           for(k=1,llt=0.,l=0.; k<=nlstate; k++){
   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);            llt +=ll[k]*gipmx/gsw;
   delti=vector(1,npar); /* Scale of each paramater (output from hesscov) */            fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
   for(i=1; i <=nlstate; i++){          }
     for(j=1; j <=nlstate+ndeath-1; j++){          fprintf(ficresilk," %10.6f\n", -llt);
       fscanf(ficpar,"%1d%1d",&i1,&j1);        }
       printf("%1d%1d",i,j);      } /* end of wave */
       fprintf(ficparo,"%1d%1d",i1,j1);    } /* end of individual */
       for(k=1; k<=ncovmodel;k++){    for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
         fscanf(ficpar,"%le",&delti3[i][j][k]);    /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
         printf(" %le",delti3[i][j][k]);    l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
         fprintf(ficparo," %le",delti3[i][j][k]);    if(globpr==0){ /* First time we count the contributions and weights */
       }      gipmx=ipmx;
       fscanf(ficpar,"\n");      gsw=sw;
       printf("\n");    }
       fprintf(ficparo,"\n");    return -l;
     }  }
   }  
   delti=delti3[1][1];  
    /*************** function likelione ***********/
   /* Reads comments: lines beginning with '#' */  void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
   while((c=getc(ficpar))=='#' && c!= EOF){  {
     ungetc(c,ficpar);    /* This routine should help understanding what is done with 
     fgets(line, MAXLINE, ficpar);       the selection of individuals/waves and
     puts(line);       to check the exact contribution to the likelihood.
     fputs(line,ficparo);       Plotting could be done.
   }     */
   ungetc(c,ficpar);    int k;
    
   matcov=matrix(1,npar,1,npar);    if(*globpri !=0){ /* Just counts and sums, no printings */
   for(i=1; i <=npar; i++){      strcpy(fileresilk,"ilk"); 
     fscanf(ficpar,"%s",&str);      strcat(fileresilk,fileres);
     printf("%s",str);      if((ficresilk=fopen(fileresilk,"w"))==NULL) {
     fprintf(ficparo,"%s",str);        printf("Problem with resultfile: %s\n", fileresilk);
     for(j=1; j <=i; j++){        fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
       fscanf(ficpar," %le",&matcov[i][j]);      }
       printf(" %.5le",matcov[i][j]);      fprintf(ficresilk, "#individual(line's_record) s1 s2 wave# effective_wave# number_of_matrices_product pij weight -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
       fprintf(ficparo," %.5le",matcov[i][j]);      fprintf(ficresilk, "#num_i i s1 s2 mi mw dh likeli weight 2wlli out sav ");
     }      /*  i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
     fscanf(ficpar,"\n");      for(k=1; k<=nlstate; k++) 
     printf("\n");        fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
     fprintf(ficparo,"\n");      fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
   }    }
   for(i=1; i <=npar; i++)  
     for(j=i+1;j<=npar;j++)    *fretone=(*funcone)(p);
       matcov[i][j]=matcov[j][i];    if(*globpri !=0){
          fclose(ficresilk);
   printf("\n");      fprintf(fichtm,"\n<br>File of contributions to the likelihood: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
       fflush(fichtm); 
     } 
     /*-------- data file ----------*/    return;
     if((ficres =fopen(fileres,"w"))==NULL) {  }
       printf("Problem with resultfile: %s\n", fileres);goto end;  
     }  
     fprintf(ficres,"#%s\n",version);  /*********** Maximum Likelihood Estimation ***************/
      
     if((fic=fopen(datafile,"r"))==NULL)    {  void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
       printf("Problem with datafile: %s\n", datafile);goto end;  {
     }    int i,j, iter;
     double **xi;
     n= lastobs;    double fret;
     severity = vector(1,maxwav);    double fretone; /* Only one call to likelihood */
     outcome=imatrix(1,maxwav+1,1,n);    /*  char filerespow[FILENAMELENGTH];*/
     num=ivector(1,n);    xi=matrix(1,npar,1,npar);
     moisnais=vector(1,n);    for (i=1;i<=npar;i++)
     annais=vector(1,n);      for (j=1;j<=npar;j++)
     moisdc=vector(1,n);        xi[i][j]=(i==j ? 1.0 : 0.0);
     andc=vector(1,n);    printf("Powell\n");  fprintf(ficlog,"Powell\n");
     agedc=vector(1,n);    strcpy(filerespow,"pow"); 
     cod=ivector(1,n);    strcat(filerespow,fileres);
     weight=vector(1,n);    if((ficrespow=fopen(filerespow,"w"))==NULL) {
     for(i=1;i<=n;i++) weight[i]=1.0; /* Equal weights, 1 by default */      printf("Problem with resultfile: %s\n", filerespow);
     mint=matrix(1,maxwav,1,n);      fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
     anint=matrix(1,maxwav,1,n);    }
     s=imatrix(1,maxwav+1,1,n);    fprintf(ficrespow,"# Powell\n# iter -2*LL");
     adl=imatrix(1,maxwav+1,1,n);        for (i=1;i<=nlstate;i++)
     tab=ivector(1,NCOVMAX);      for(j=1;j<=nlstate+ndeath;j++)
     ncodemax=ivector(1,8);        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
     fprintf(ficrespow,"\n");
     i=1;  
     while (fgets(line, MAXLINE, fic) != NULL)    {    powell(p,xi,npar,ftol,&iter,&fret,func);
       if ((i >= firstobs) && (i <=lastobs)) {  
            free_matrix(xi,1,npar,1,npar);
         for (j=maxwav;j>=1;j--){    fclose(ficrespow);
           cutv(stra, strb,line,' '); s[j][i]=atoi(strb);    printf("\n#Number of iterations = %d, -2 Log likelihood = %.12f\n",iter,func(p));
           strcpy(line,stra);    fprintf(ficlog,"\n#Number of iterations = %d, -2 Log likelihood = %.12f \n",iter,func(p));
           cutv(stra, strb,line,'/'); anint[j][i]=(double)(atoi(strb)); strcpy(line,stra);    fprintf(ficres,"#Number of iterations = %d, -2 Log likelihood = %.12f \n",iter,func(p));
           cutv(stra, strb,line,' '); mint[j][i]=(double)(atoi(strb)); strcpy(line,stra);  
         }  }
          
         cutv(stra, strb,line,'/'); andc[i]=(double)(atoi(strb)); strcpy(line,stra);  /**** Computes Hessian and covariance matrix ***/
         cutv(stra, strb,line,' '); moisdc[i]=(double)(atoi(strb)); strcpy(line,stra);  void hesscov(double **matcov, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
   {
         cutv(stra, strb,line,'/'); annais[i]=(double)(atoi(strb)); strcpy(line,stra);    double  **a,**y,*x,pd;
         cutv(stra, strb,line,' '); moisnais[i]=(double)(atoi(strb)); strcpy(line,stra);    double **hess;
     int i, j,jk;
         cutv(stra, strb,line,' '); weight[i]=(double)(atoi(strb)); strcpy(line,stra);    int *indx;
         for (j=ncov;j>=1;j--){  
           cutv(stra, strb,line,' '); covar[j][i]=(double)(atoi(strb)); strcpy(line,stra);    double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
         }    double hessij(double p[], double delti[], int i, int j,double (*func)(double []),int npar);
         num[i]=atol(stra);    void lubksb(double **a, int npar, int *indx, double b[]) ;
            void ludcmp(double **a, int npar, int *indx, double *d) ;
         /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){    double gompertz(double p[]);
           printf("%d %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/    hess=matrix(1,npar,1,npar);
   
         i=i+1;    printf("\nCalculation of the hessian matrix. Wait...\n");
       }    fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
     }    for (i=1;i<=npar;i++){
     /* printf("ii=%d", ij);      printf("%d",i);fflush(stdout);
        scanf("%d",i);*/      fprintf(ficlog,"%d",i);fflush(ficlog);
   imx=i-1; /* Number of individuals */     
        hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
   /* for (i=1; i<=imx; i++){      
     if ((s[1][i]==3) && (s[2][i]==2)) s[2][i]=3;      /*  printf(" %f ",p[i]);
     if ((s[2][i]==3) && (s[3][i]==2)) s[3][i]=3;          printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
     if ((s[3][i]==3) && (s[4][i]==2)) s[4][i]=3;    }
     }    
     for (i=1; i<=imx; i++) printf("%d %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]), (weight[i]), (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i]));*/    for (i=1;i<=npar;i++) {
       for (j=1;j<=npar;j++)  {
   /* Calculation of the number of parameter from char model*/        if (j>i) { 
   Tvar=ivector(1,15);          printf(".%d%d",i,j);fflush(stdout);
   Tprod=ivector(1,15);          fprintf(ficlog,".%d%d",i,j);fflush(ficlog);
   Tvaraff=ivector(1,15);          hess[i][j]=hessij(p,delti,i,j,func,npar);
   Tvard=imatrix(1,15,1,2);          
   Tage=ivector(1,15);                hess[j][i]=hess[i][j];    
              /*printf(" %lf ",hess[i][j]);*/
   if (strlen(model) >1){        }
     j=0, j1=0, k1=1, k2=1;      }
     j=nbocc(model,'+');    }
     j1=nbocc(model,'*');    printf("\n");
     cptcovn=j+1;    fprintf(ficlog,"\n");
     cptcovprod=j1;  
        printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
        fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
     strcpy(modelsav,model);    
     if ((strcmp(model,"age")==0) || (strcmp(model,"age*age")==0)){    a=matrix(1,npar,1,npar);
       printf("Error. Non available option model=%s ",model);    y=matrix(1,npar,1,npar);
       goto end;    x=vector(1,npar);
     }    indx=ivector(1,npar);
        for (i=1;i<=npar;i++)
     for(i=(j+1); i>=1;i--){      for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
       cutv(stra,strb,modelsav,'+');    ludcmp(a,npar,indx,&pd);
       if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav);  
       /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/    for (j=1;j<=npar;j++) {
       /*scanf("%d",i);*/      for (i=1;i<=npar;i++) x[i]=0;
       if (strchr(strb,'*')) {      x[j]=1;
         cutv(strd,strc,strb,'*');      lubksb(a,npar,indx,x);
         if (strcmp(strc,"age")==0) {      for (i=1;i<=npar;i++){ 
           cptcovprod--;        matcov[i][j]=x[i];
           cutv(strb,stre,strd,'V');      }
           Tvar[i]=atoi(stre);    }
           cptcovage++;  
             Tage[cptcovage]=i;    printf("\n#Hessian matrix#\n");
             /*printf("stre=%s ", stre);*/    fprintf(ficlog,"\n#Hessian matrix#\n");
         }    for (i=1;i<=npar;i++) { 
         else if (strcmp(strd,"age")==0) {      for (j=1;j<=npar;j++) { 
           cptcovprod--;        printf("%.3e ",hess[i][j]);
           cutv(strb,stre,strc,'V');        fprintf(ficlog,"%.3e ",hess[i][j]);
           Tvar[i]=atoi(stre);      }
           cptcovage++;      printf("\n");
           Tage[cptcovage]=i;      fprintf(ficlog,"\n");
         }    }
         else {  
           cutv(strb,stre,strc,'V');    /* Recompute Inverse */
           Tvar[i]=ncov+k1;    for (i=1;i<=npar;i++)
           cutv(strb,strc,strd,'V');      for (j=1;j<=npar;j++) a[i][j]=matcov[i][j];
           Tprod[k1]=i;    ludcmp(a,npar,indx,&pd);
           Tvard[k1][1]=atoi(strc);  
           Tvard[k1][2]=atoi(stre);    /*  printf("\n#Hessian matrix recomputed#\n");
           Tvar[cptcovn+k2]=Tvard[k1][1];  
           Tvar[cptcovn+k2+1]=Tvard[k1][2];    for (j=1;j<=npar;j++) {
           for (k=1; k<=lastobs;k++)      for (i=1;i<=npar;i++) x[i]=0;
             covar[ncov+k1][k]=covar[atoi(stre)][k]*covar[atoi(strc)][k];      x[j]=1;
           k1++;      lubksb(a,npar,indx,x);
           k2=k2+2;      for (i=1;i<=npar;i++){ 
         }        y[i][j]=x[i];
       }        printf("%.3e ",y[i][j]);
       else {        fprintf(ficlog,"%.3e ",y[i][j]);
         /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/      }
        /*  scanf("%d",i);*/      printf("\n");
       cutv(strd,strc,strb,'V');      fprintf(ficlog,"\n");
       Tvar[i]=atoi(strc);    }
       }    */
       strcpy(modelsav,stra);    
       /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);    free_matrix(a,1,npar,1,npar);
         scanf("%d",i);*/    free_matrix(y,1,npar,1,npar);
     }    free_vector(x,1,npar);
 }    free_ivector(indx,1,npar);
      free_matrix(hess,1,npar,1,npar);
   /*printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);  
   printf("cptcovprod=%d ", cptcovprod);  
   scanf("%d ",i);*/  }
     fclose(fic);  
   /*************** hessian matrix ****************/
     /*  if(mle==1){*/  double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
     if (weightopt != 1) { /* Maximisation without weights*/  {
       for(i=1;i<=n;i++) weight[i]=1.0;    int i;
     }    int l=1, lmax=20;
     /*-calculation of age at interview from date of interview and age at death -*/    double k1,k2;
     agev=matrix(1,maxwav,1,imx);    double p2[MAXPARM+1]; /* identical to x */
     double res;
    for (i=1; i<=imx; i++)    double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
      for(m=2; (m<= maxwav); m++)    double fx;
        if ((mint[m][i]== 99) && (s[m][i] <= nlstate)){    int k=0,kmax=10;
          anint[m][i]=9999;    double l1;
          s[m][i]=-1;  
        }    fx=func(x);
        for (i=1;i<=npar;i++) p2[i]=x[i];
     for (i=1; i<=imx; i++)  {    for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
       agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);      l1=pow(10,l);
       for(m=1; (m<= maxwav); m++){      delts=delt;
         if(s[m][i] >0){      for(k=1 ; k <kmax; k=k+1){
           if (s[m][i] == nlstate+1) {        delt = delta*(l1*k);
             if(agedc[i]>0)        p2[theta]=x[theta] +delt;
               if(moisdc[i]!=99 && andc[i]!=9999)        k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
               agev[m][i]=agedc[i];        p2[theta]=x[theta]-delt;
             else {        k2=func(p2)-fx;
               if (andc[i]!=9999){        /*res= (k1-2.0*fx+k2)/delt/delt; */
               printf("Warning negative age at death: %d line:%d\n",num[i],i);        res= (k1+k2)/delt/delt/2.; /* Divided by because L and not 2*L */
               agev[m][i]=-1;        
               }  #ifdef DEBUGHESS
             }        printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
           }        fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
           else if(s[m][i] !=9){ /* Should no more exist */  #endif
             agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);        /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
             if(mint[m][i]==99 || anint[m][i]==9999)        if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
               agev[m][i]=1;          k=kmax;
             else if(agev[m][i] <agemin){        }
               agemin=agev[m][i];        else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
               /*printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], agemin);*/          k=kmax; l=lmax*10.;
             }        }
             else if(agev[m][i] >agemax){        else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
               agemax=agev[m][i];          delts=delt;
              /* printf(" anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.0f\n",m,i,anint[m][i], i,annais[i], agemax);*/        }
             }      }
             /*agev[m][i]=anint[m][i]-annais[i];*/    }
             /*   agev[m][i] = age[i]+2*m;*/    delti[theta]=delts;
           }    return res; 
           else { /* =9 */    
             agev[m][i]=1;  }
             s[m][i]=-1;  
           }  double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
         }  {
         else /*= 0 Unknown */    int i;
           agev[m][i]=1;    int l=1, l1, lmax=20;
       }    double k1,k2,k3,k4,res,fx;
        double p2[MAXPARM+1];
     }    int k;
     for (i=1; i<=imx; i++)  {  
       for(m=1; (m<= maxwav); m++){    fx=func(x);
         if (s[m][i] > (nlstate+ndeath)) {    for (k=1; k<=2; k++) {
           printf("Error: Wrong value in nlstate or ndeath\n");        for (i=1;i<=npar;i++) p2[i]=x[i];
           goto end;      p2[thetai]=x[thetai]+delti[thetai]/k;
         }      p2[thetaj]=x[thetaj]+delti[thetaj]/k;
       }      k1=func(p2)-fx;
     }    
       p2[thetai]=x[thetai]+delti[thetai]/k;
 printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, agemin, agemax);      p2[thetaj]=x[thetaj]-delti[thetaj]/k;
       k2=func(p2)-fx;
     free_vector(severity,1,maxwav);    
     free_imatrix(outcome,1,maxwav+1,1,n);      p2[thetai]=x[thetai]-delti[thetai]/k;
     free_vector(moisnais,1,n);      p2[thetaj]=x[thetaj]+delti[thetaj]/k;
     free_vector(annais,1,n);      k3=func(p2)-fx;
     free_matrix(mint,1,maxwav,1,n);    
     free_matrix(anint,1,maxwav,1,n);      p2[thetai]=x[thetai]-delti[thetai]/k;
     free_vector(moisdc,1,n);      p2[thetaj]=x[thetaj]-delti[thetaj]/k;
     free_vector(andc,1,n);      k4=func(p2)-fx;
       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /* Because of L not 2*L */
      #ifdef DEBUG
     wav=ivector(1,imx);      printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
     dh=imatrix(1,lastpass-firstpass+1,1,imx);      fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
     mw=imatrix(1,lastpass-firstpass+1,1,imx);  #endif
        }
     /* Concatenates waves */    return res;
       concatwav(wav, dh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);  }
   
   /************** Inverse of matrix **************/
       Tcode=ivector(1,100);  void ludcmp(double **a, int n, int *indx, double *d) 
       nbcode=imatrix(0,NCOVMAX,0,NCOVMAX);  { 
       ncodemax[1]=1;    int i,imax,j,k; 
       if (cptcovn > 0) tricode(Tvar,nbcode,imx);    double big,dum,sum,temp; 
          double *vv; 
    codtab=imatrix(1,100,1,10);   
    h=0;    vv=vector(1,n); 
    m=pow(2,cptcoveff);    *d=1.0; 
      for (i=1;i<=n;i++) { 
    for(k=1;k<=cptcoveff; k++){      big=0.0; 
      for(i=1; i <=(m/pow(2,k));i++){      for (j=1;j<=n;j++) 
        for(j=1; j <= ncodemax[k]; j++){        if ((temp=fabs(a[i][j])) > big) big=temp; 
          for(cpt=1; cpt <=(m/pow(2,cptcoveff+1-k)); cpt++){      if (big == 0.0) nrerror("Singular matrix in routine ludcmp"); 
            h++;      vv[i]=1.0/big; 
            if (h>m) h=1;codtab[h][k]=j;    } 
          }    for (j=1;j<=n;j++) { 
        }      for (i=1;i<j;i++) { 
      }        sum=a[i][j]; 
    }        for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
         a[i][j]=sum; 
       } 
    /*for(i=1; i <=m ;i++){      big=0.0; 
      for(k=1; k <=cptcovn; k++){      for (i=j;i<=n;i++) { 
        printf("i=%d k=%d %d %d",i,k,codtab[i][k], cptcoveff);        sum=a[i][j]; 
      }        for (k=1;k<j;k++) 
      printf("\n");          sum -= a[i][k]*a[k][j]; 
    }        a[i][j]=sum; 
    scanf("%d",i);*/        if ( (dum=vv[i]*fabs(sum)) >= big) { 
              big=dum; 
    /* Calculates basic frequencies. Computes observed prevalence at single age          imax=i; 
        and prints on file fileres'p'. */        } 
   freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax);      } 
       if (j != imax) { 
     pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */        for (k=1;k<=n;k++) { 
     oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */          dum=a[imax][k]; 
     newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */          a[imax][k]=a[j][k]; 
     savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */          a[j][k]=dum; 
     oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */        } 
              *d = -(*d); 
     /* For Powell, parameters are in a vector p[] starting at p[1]        vv[imax]=vv[j]; 
        so we point p on param[1][1] so that p[1] maps on param[1][1][1] */      } 
     p=param[1][1]; /* *(*(*(param +1)+1)+0) */      indx[j]=imax; 
       if (a[j][j] == 0.0) a[j][j]=TINY; 
     if(mle==1){      if (j != n) { 
     mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);        dum=1.0/(a[j][j]); 
     }        for (i=j+1;i<=n;i++) a[i][j] *= dum; 
          } 
     /*--------- results files --------------*/    } 
     fprintf(ficres,"\ntitle=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncov=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncov, nlstate, ndeath, maxwav, mle,weightopt,model);    free_vector(vv,1,n);  /* Doesn't work */
      ;
    jk=1;  } 
    fprintf(ficres,"# Parameters\n");  
    printf("# Parameters\n");  void lubksb(double **a, int n, int *indx, double b[]) 
    for(i=1,jk=1; i <=nlstate; i++){  { 
      for(k=1; k <=(nlstate+ndeath); k++){    int i,ii=0,ip,j; 
        if (k != i)    double sum; 
          {   
            printf("%d%d ",i,k);    for (i=1;i<=n;i++) { 
            fprintf(ficres,"%1d%1d ",i,k);      ip=indx[i]; 
            for(j=1; j <=ncovmodel; j++){      sum=b[ip]; 
              printf("%f ",p[jk]);      b[ip]=b[i]; 
              fprintf(ficres,"%f ",p[jk]);      if (ii) 
              jk++;        for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
            }      else if (sum) ii=i; 
            printf("\n");      b[i]=sum; 
            fprintf(ficres,"\n");    } 
          }    for (i=n;i>=1;i--) { 
      }      sum=b[i]; 
    }      for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
  if(mle==1){      b[i]=sum/a[i][i]; 
     /* Computing hessian and covariance matrix */    } 
     ftolhess=ftol; /* Usually correct */  } 
     hesscov(matcov, p, npar, delti, ftolhess, func);  
  }  void pstamp(FILE *fichier)
     fprintf(ficres,"# Scales\n");  {
     printf("# Scales\n");    fprintf(fichier,"# %s.%s\n#%s\n#%s\n# %s", optionfilefiname,optionfilext,version,fullversion,strstart);
      for(i=1,jk=1; i <=nlstate; i++){  }
       for(j=1; j <=nlstate+ndeath; j++){  
         if (j!=i) {  /************ Frequencies ********************/
           fprintf(ficres,"%1d%1d",i,j);  void  freqsummary(char fileres[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, int *Tvaraff, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[])
           printf("%1d%1d",i,j);  {  /* Some frequencies */
           for(k=1; k<=ncovmodel;k++){    
             printf(" %.5e",delti[jk]);    int i, m, jk, k1,i1, j1, bool, z1,j;
             fprintf(ficres," %.5e",delti[jk]);    int first;
             jk++;    double ***freq; /* Frequencies */
           }    double *pp, **prop;
           printf("\n");    double pos,posprop, k2, dateintsum=0,k2cpt=0;
           fprintf(ficres,"\n");    char fileresp[FILENAMELENGTH];
         }    
       }    pp=vector(1,nlstate);
       }    prop=matrix(1,nlstate,iagemin,iagemax+3);
        strcpy(fileresp,"p");
     k=1;    strcat(fileresp,fileres);
     fprintf(ficres,"# Covariance\n");    if((ficresp=fopen(fileresp,"w"))==NULL) {
     printf("# Covariance\n");      printf("Problem with prevalence resultfile: %s\n", fileresp);
     for(i=1;i<=npar;i++){      fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
       /*  if (k>nlstate) k=1;      exit(0);
       i1=(i-1)/(ncovmodel*nlstate)+1;    }
       fprintf(ficres,"%s%d%d",alph[k],i1,tab[i]);    freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin,iagemax+3);
       printf("%s%d%d",alph[k],i1,tab[i]);*/    j1=0;
       fprintf(ficres,"%3d",i);    
       printf("%3d",i);    j=cptcoveff;
       for(j=1; j<=i;j++){    if (cptcovn<1) {j=1;ncodemax[1]=1;}
         fprintf(ficres," %.5e",matcov[i][j]);  
         printf(" %.5e",matcov[i][j]);    first=1;
       }  
       fprintf(ficres,"\n");    /* for(k1=1; k1<=j ; k1++){   /* Loop on covariates */
       printf("\n");    /*  for(i1=1; i1<=ncodemax[k1];i1++){ /* Now it is 2 */
       k++;    /*    j1++;
     }  */
        for (j1 = 1; j1 <= (int) pow(2,cptcoveff); j1++){
     while((c=getc(ficpar))=='#' && c!= EOF){        /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
       ungetc(c,ficpar);          scanf("%d", i);*/
       fgets(line, MAXLINE, ficpar);        for (i=-5; i<=nlstate+ndeath; i++)  
       puts(line);          for (jk=-5; jk<=nlstate+ndeath; jk++)  
       fputs(line,ficparo);            for(m=iagemin; m <= iagemax+3; m++)
     }              freq[i][jk][m]=0;
     ungetc(c,ficpar);        
          for (i=1; i<=nlstate; i++)  
     fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf\n",&agemin,&agemax, &bage, &fage);          for(m=iagemin; m <= iagemax+3; m++)
                prop[i][m]=0;
     if (fage <= 2) {        
       bage = agemin;        dateintsum=0;
       fage = agemax;        k2cpt=0;
     }        for (i=1; i<=imx; i++) {
           bool=1;
     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");          if  (cptcovn>0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f\n",agemin,agemax,bage,fage);            for (z1=1; z1<=cptcoveff; z1++)       
               if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtab[j1][z1]]){
                      /* Tests if the value of each of the covariates of i is equal to filter j1 */
 /*------------ gnuplot -------------*/                bool=0;
 chdir(pathcd);                /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtab[%d][%d]=%d, nbcode[Tvaraff][codtab[%d][%d]=%d, j1=%d\n", 
   if((ficgp=fopen("graph.plt","w"))==NULL) {                  bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtab[j1][z1],
     printf("Problem with file graph.gp");goto end;                  j1,z1,nbcode[Tvaraff[z1]][codtab[j1][z1]],j1);*/
   }                /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtab[7][3]=1 and nbcde[3][?]=1*/
 #ifdef windows              } 
   fprintf(ficgp,"cd \"%s\" \n",pathc);          }
 #endif   
 m=pow(2,cptcoveff);          if (bool==1){
              for(m=firstpass; m<=lastpass; m++){
  /* 1eme*/              k2=anint[m][i]+(mint[m][i]/12.);
   for (cpt=1; cpt<= nlstate ; cpt ++) {              /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
    for (k1=1; k1<= m ; k1 ++) {                if(agev[m][i]==0) agev[m][i]=iagemax+1;
                 if(agev[m][i]==1) agev[m][i]=iagemax+2;
 #ifdef windows                if (s[m][i]>0 && s[m][i]<=nlstate) prop[s[m][i]][(int)agev[m][i]] += weight[i];
     fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter gif small size 400,300\nplot [%.f:%.f] \"vpl%s\" every :::%d::%d u 1:2 \"\%%lf",agemin,fage,fileres,k1-1,k1-1);                if (m<lastpass) {
 #endif                  freq[s[m][i]][s[m+1][i]][(int)agev[m][i]] += weight[i];
 #ifdef unix                  freq[s[m][i]][s[m+1][i]][iagemax+3] += weight[i];
 fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nplot [%.f:%.f] \"vpl%s\" u 1:2 \"\%%lf",agemin,fage,fileres);                }
 #endif                
                 if ((agev[m][i]>1) && (agev[m][i]< (iagemax+3))) {
 for (i=1; i<= nlstate ; i ++) {                  dateintsum=dateintsum+k2;
   if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");                  k2cpt++;
   else fprintf(ficgp," \%%*lf (\%%*lf)");                }
 }                /*}*/
     fprintf(ficgp,"\" t\"Stationary prevalence\" w l 0,\"vpl%s\" every :::%d::%d u 1:($2+2*$3) \"\%%lf",fileres,k1-1,k1-1);            }
     for (i=1; i<= nlstate ; i ++) {          }
   if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");        } /* end i */
   else fprintf(ficgp," \%%*lf (\%%*lf)");         
 }        /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
   fprintf(ficgp,"\" t\"95\%% CI\" w l 1,\"vpl%s\" every :::%d::%d u 1:($2-2*$3) \"\%%lf",fileres,k1-1,k1-1);        pstamp(ficresp);
      for (i=1; i<= nlstate ; i ++) {        if  (cptcovn>0) {
   if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");          fprintf(ficresp, "\n#********** Variable "); 
   else fprintf(ficgp," \%%*lf (\%%*lf)");          for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
 }            fprintf(ficresp, "**********\n#");
      fprintf(ficgp,"\" t\"\" w l 1,\"p%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence \" w l 2",fileres,k1-1,k1-1,2+4*(cpt-1));          fprintf(ficlog, "\n#********** Variable "); 
 #ifdef unix          for (z1=1; z1<=cptcoveff; z1++) fprintf(ficlog, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
 fprintf(ficgp,"\nset ter gif small size 400,300");          fprintf(ficlog, "**********\n#");
 #endif        }
 fprintf(ficgp,"\nset out \"v%s%d%d.gif\" \nreplot\n\n",strtok(optionfile, "."),cpt,k1);        for(i=1; i<=nlstate;i++) 
    }          fprintf(ficresp, " Age Prev(%d) N(%d) N",i,i);
   }        fprintf(ficresp, "\n");
   /*2 eme*/        
         for(i=iagemin; i <= iagemax+3; i++){
   for (k1=1; k1<= m ; k1 ++) {          if(i==iagemax+3){
     fprintf(ficgp,"set ylabel \"Years\" \nset ter gif small size 400,300\nplot [%.f:%.f] ",agemin,fage);            fprintf(ficlog,"Total");
              }else{
     for (i=1; i<= nlstate+1 ; i ++) {            if(first==1){
       k=2*i;              first=0;
       fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:2 \"\%%lf",fileres,k1-1,k1-1);              printf("See log file for details...\n");
       for (j=1; j<= nlstate+1 ; j ++) {            }
   if (j==i) fprintf(ficgp," \%%lf (\%%lf)");            fprintf(ficlog,"Age %d", i);
   else fprintf(ficgp," \%%*lf (\%%*lf)");          }
 }            for(jk=1; jk <=nlstate ; jk++){
       if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l ,");            for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
       else fprintf(ficgp,"\" t\"LE in state (%d)\" w l ,",i-1);              pp[jk] += freq[jk][m][i]; 
     fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:($2-$3*2) \"\%%lf",fileres,k1-1,k1-1);          }
       for (j=1; j<= nlstate+1 ; j ++) {          for(jk=1; jk <=nlstate ; jk++){
         if (j==i) fprintf(ficgp," \%%lf (\%%lf)");            for(m=-1, pos=0; m <=0 ; m++)
         else fprintf(ficgp," \%%*lf (\%%*lf)");              pos += freq[jk][m][i];
 }              if(pp[jk]>=1.e-10){
       fprintf(ficgp,"\" t\"\" w l 0,");              if(first==1){
      fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:($2+$3*2) \"\%%lf",fileres,k1-1,k1-1);                printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
       for (j=1; j<= nlstate+1 ; j ++) {              }
   if (j==i) fprintf(ficgp," \%%lf (\%%lf)");              fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
   else fprintf(ficgp," \%%*lf (\%%*lf)");            }else{
 }                if(first==1)
       if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l 0");                printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
       else fprintf(ficgp,"\" t\"\" w l 0,");              fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
     }            }
     fprintf(ficgp,"\nset out \"e%s%d.gif\" \nreplot\n\n",strtok(optionfile, "."),k1);          }
   }  
            for(jk=1; jk <=nlstate ; jk++){
   /*3eme*/            for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)
               pp[jk] += freq[jk][m][i];
   for (k1=1; k1<= m ; k1 ++) {          }       
     for (cpt=1; cpt<= nlstate ; cpt ++) {          for(jk=1,pos=0,posprop=0; jk <=nlstate ; jk++){
       k=2+nlstate*(cpt-1);            pos += pp[jk];
       fprintf(ficgp,"set ter gif small size 400,300\nplot [%.f:%.f] \"e%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",agemin,fage,fileres,k1-1,k1-1,k,cpt);            posprop += prop[jk][i];
       for (i=1; i< nlstate ; i ++) {          }
         fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",fileres,k1-1,k1-1,k+i,cpt,i+1);          for(jk=1; jk <=nlstate ; jk++){
       }            if(pos>=1.e-5){
       fprintf(ficgp,"\nset out \"exp%s%d%d.gif\" \nreplot\n\n",strtok(optionfile, "."),cpt,k1);              if(first==1)
     }                printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
   }              fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
              }else{
   /* CV preval stat */              if(first==1)
   for (k1=1; k1<= m ; k1 ++) {                printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
     for (cpt=1; cpt<nlstate ; cpt ++) {              fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
       k=3;            }
       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter gif small size 400,300\nplot [%.f:%.f] \"pij%s\" u ($1==%d ? ($3):1/0):($%d/($%d",agemin,agemax,fileres,k1,k+cpt+1,k+1);            if( i <= iagemax){
       for (i=1; i< nlstate ; i ++)              if(pos>=1.e-5){
         fprintf(ficgp,"+$%d",k+i+1);                fprintf(ficresp," %d %.5f %.0f %.0f",i,prop[jk][i]/posprop, prop[jk][i],posprop);
       fprintf(ficgp,")) t\"prev(%d,%d)\" w l",cpt,cpt+1);                /*probs[i][jk][j1]= pp[jk]/pos;*/
                      /*printf("\ni=%d jk=%d j1=%d %.5f %.0f %.0f %f",i,jk,j1,pp[jk]/pos, pp[jk],pos,probs[i][jk][j1]);*/
       l=3+(nlstate+ndeath)*cpt;              }
       fprintf(ficgp,",\"pij%s\" u ($1==%d ? ($3):1/0):($%d/($%d",fileres,k1,l+cpt+1,l+1);              else
       for (i=1; i< nlstate ; i ++) {                fprintf(ficresp," %d NaNq %.0f %.0f",i,prop[jk][i],posprop);
         l=3+(nlstate+ndeath)*cpt;            }
         fprintf(ficgp,"+$%d",l+i+1);          }
       }          
       fprintf(ficgp,")) t\"prev(%d,%d)\" w l\n",cpt+1,cpt+1);            for(jk=-1; jk <=nlstate+ndeath; jk++)
       fprintf(ficgp,"set out \"p%s%d%d.gif\" \nreplot\n\n",strtok(optionfile, "."),cpt,k1);            for(m=-1; m <=nlstate+ndeath; m++)
     }              if(freq[jk][m][i] !=0 ) {
   }                if(first==1)
                 printf(" %d%d=%.0f",jk,m,freq[jk][m][i]);
   /* proba elementaires */                fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][i]);
    for(i=1,jk=1; i <=nlstate; i++){              }
     for(k=1; k <=(nlstate+ndeath); k++){          if(i <= iagemax)
       if (k != i) {            fprintf(ficresp,"\n");
         for(j=1; j <=ncovmodel; j++){          if(first==1)
           /*fprintf(ficgp,"%s%1d%1d=%f ",alph[j],i,k,p[jk]);*/            printf("Others in log...\n");
           /*fprintf(ficgp,"%s",alph[1]);*/          fprintf(ficlog,"\n");
           fprintf(ficgp,"p%d=%f ",jk,p[jk]);        }
           jk++;        /*}*/
           fprintf(ficgp,"\n");    }
         }    dateintmean=dateintsum/k2cpt; 
       }   
     }    fclose(ficresp);
     }    free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin, iagemax+3);
     free_vector(pp,1,nlstate);
   for(jk=1; jk <=m; jk++) {    free_matrix(prop,1,nlstate,iagemin, iagemax+3);
   fprintf(ficgp,"\nset ter gif small size 400,300\nset log y\nplot  [%.f:%.f] ",agemin,agemax);    /* End of Freq */
    i=1;  }
    for(k2=1; k2<=nlstate; k2++) {  
      k3=i;  /************ Prevalence ********************/
      for(k=1; k<=(nlstate+ndeath); k++) {  void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
        if (k != k2){  {  
         fprintf(ficgp," exp(p%d+p%d*x",i,i+1);    /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
 ij=1;       in each health status at the date of interview (if between dateprev1 and dateprev2).
         for(j=3; j <=ncovmodel; j++) {       We still use firstpass and lastpass as another selection.
           if(((j-2)==Tage[ij]) &&(ij <=cptcovage)) {    */
             fprintf(ficgp,"+p%d*%d*x",i+j-1,nbcode[Tvar[j-2]][codtab[jk][Tvar[j-2]]]);   
             ij++;    int i, m, jk, k1, i1, j1, bool, z1,j;
           }    double ***freq; /* Frequencies */
           else    double *pp, **prop;
           fprintf(ficgp,"+p%d*%d",i+j-1,nbcode[Tvar[j-2]][codtab[jk][j-2]]);    double pos,posprop; 
         }    double  y2; /* in fractional years */
           fprintf(ficgp,")/(1");    int iagemin, iagemax;
            int first; /** to stop verbosity which is redirected to log file */
         for(k1=1; k1 <=nlstate; k1++){    
           fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);    iagemin= (int) agemin;
 ij=1;    iagemax= (int) agemax;
           for(j=3; j <=ncovmodel; j++){    /*pp=vector(1,nlstate);*/
           if(((j-2)==Tage[ij]) &&(ij <=cptcovage)) {    prop=matrix(1,nlstate,iagemin,iagemax+3); 
             fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2,nbcode[Tvar[j-2]][codtab[jk][Tvar[j-2]]]);    /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
             ij++;    j1=0;
           }    
           else    /*j=cptcoveff;*/
             fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2,nbcode[Tvar[j-2]][codtab[jk][j-2]]);    if (cptcovn<1) {j=1;ncodemax[1]=1;}
           }    
           fprintf(ficgp,")");    first=1;
         }    for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){
         fprintf(ficgp,") t \"p%d%d\" ", k2,k);      /*for(i1=1; i1<=ncodemax[k1];i1++){
         if ((k+k2)!= (nlstate*2+ndeath)) fprintf(ficgp,",");        j1++;*/
         i=i+ncovmodel;        
        }        for (i=1; i<=nlstate; i++)  
      }          for(m=iagemin; m <= iagemax+3; m++)
    }            prop[i][m]=0.0;
    fprintf(ficgp,"\nset out \"pe%s%d.gif\" \nreplot\n\n",strtok(optionfile, "."),jk);       
   }        for (i=1; i<=imx; i++) { /* Each individual */
              bool=1;
   fclose(ficgp);          if  (cptcovn>0) {
                for (z1=1; z1<=cptcoveff; z1++) 
 chdir(path);              if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtab[j1][z1]]) 
     free_matrix(agev,1,maxwav,1,imx);                bool=0;
     free_ivector(wav,1,imx);          } 
     free_imatrix(dh,1,lastpass-firstpass+1,1,imx);          if (bool==1) { 
     free_imatrix(mw,1,lastpass-firstpass+1,1,imx);            for(m=firstpass; m<=lastpass; m++){/* Other selection (we can limit to certain interviews*/
                  y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
     free_imatrix(s,1,maxwav+1,1,n);              if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                    if(agev[m][i]==0) agev[m][i]=iagemax+1;
                    if(agev[m][i]==1) agev[m][i]=iagemax+2;
     free_ivector(num,1,n);                if((int)agev[m][i] <iagemin || (int)agev[m][i] >iagemax+3) printf("Error on individual =%d agev[m][i]=%f m=%d\n",i, agev[m][i],m); 
     free_vector(agedc,1,n);                if (s[m][i]>0 && s[m][i]<=nlstate) { 
     free_vector(weight,1,n);                  /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
     /*free_matrix(covar,1,NCOVMAX,1,n);*/                  prop[s[m][i]][(int)agev[m][i]] += weight[i];
     fclose(ficparo);                  prop[s[m][i]][iagemax+3] += weight[i]; 
     fclose(ficres);                } 
     /*  }*/              }
                } /* end selection of waves */
    /*________fin mle=1_________*/          }
            }
         for(i=iagemin; i <= iagemax+3; i++){  
            for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
     /* No more information from the sample is required now */            posprop += prop[jk][i]; 
   /* Reads comments: lines beginning with '#' */          } 
   while((c=getc(ficpar))=='#' && c!= EOF){          
     ungetc(c,ficpar);          for(jk=1; jk <=nlstate ; jk++){     
     fgets(line, MAXLINE, ficpar);            if( i <=  iagemax){ 
     puts(line);              if(posprop>=1.e-5){ 
     fputs(line,ficparo);                probs[i][jk][j1]= prop[jk][i]/posprop;
   }              } else{
   ungetc(c,ficpar);                if(first==1){
                    first=0;
   fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf\n",&agemin,&agemax, &bage, &fage);                  printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others on log file...\n",jk,i,j1,probs[i][jk][j1]);
   printf("agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f\n",agemin,agemax, bage, fage);                }
   fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f\n",agemin,agemax,bage,fage);              }
 /*--------- index.htm --------*/            } 
           }/* end jk */ 
   strcpy(optionfilehtm,optionfile);        }/* end i */ 
   strcat(optionfilehtm,".htm");      /*} *//* end i1 */
   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {    } /* end j1 */
     printf("Problem with %s \n",optionfilehtm);goto end;    
   }    /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
     /*free_vector(pp,1,nlstate);*/
  fprintf(fichtm,"<body><ul> <font size=\"6\">Imach, Version 0.64b </font> <hr size=\"2\" color=\"#EC5E5E\">    free_matrix(prop,1,nlstate, iagemin,iagemax+3);
 Titre=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=%s<br>  }  /* End of prevalence */
 Total number of observations=%d <br>  
 Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>  /************* Waves Concatenation ***************/
 <hr  size=\"2\" color=\"#EC5E5E\">  
 <li>Outputs files<br><br>\n  void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
         - Observed prevalence in each state: <a href=\"p%s\">p%s</a> <br>\n  {
 - Estimated parameters and the covariance matrix: <a href=\"%s\">%s</a> <br>    /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
         - Stationary prevalence in each state: <a href=\"pl%s\">pl%s</a> <br>       Death is a valid wave (if date is known).
         - Transition probabilities: <a href=\"pij%s\">pij%s</a><br>       mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
         - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>       dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
         - Life expectancies by age and initial health status: <a href=\"e%s\">e%s</a> <br>       and mw[mi+1][i]. dh depends on stepm.
         - Variances of life expectancies by age and initial health status: <a href=\"v%s\">v%s</a><br>       */
         - Health expectancies with their variances: <a href=\"t%s\">t%s</a> <br>  
         - Standard deviation of stationary prevalences: <a href=\"vpl%s\">vpl%s</a> <br>    int i, mi, m;
         - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>    /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
 <br>",title,datafile,firstpass,lastpass,stepm, weightopt,model,imx,jmin,jmax,jmean,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres);       double sum=0., jmean=0.;*/
     int first;
  fprintf(fichtm," <li>Graphs</li><p>");    int j, k=0,jk, ju, jl;
     double sum=0.;
  m=cptcoveff;    first=0;
  if (cptcovn < 1) {m=1;ncodemax[1]=1;}    jmin=1e+5;
     jmax=-1;
  j1=0;    jmean=0.;
  for(k1=1; k1<=m;k1++){    for(i=1; i<=imx; i++){
    for(i1=1; i1<=ncodemax[k1];i1++){      mi=0;
        j1++;      m=firstpass;
        if (cptcovn > 0) {      while(s[m][i] <= nlstate){
          fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");        if(s[m][i]>=1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5)
          for (cpt=1; cpt<=cptcoveff;cpt++)          mw[++mi][i]=m;
            fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtab[j1][cpt]]);        if(m >=lastpass)
          fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");          break;
        }        else
        fprintf(fichtm,"<br>- Probabilities: pe%s%d.gif<br>          m++;
 <img src=\"pe%s%d.gif\">",strtok(optionfile, "."),j1,strtok(optionfile, "."),j1);          }/* end while */
        for(cpt=1; cpt<nlstate;cpt++){      if (s[m][i] > nlstate){
          fprintf(fichtm,"<br>- Prevalence of disability : p%s%d%d.gif<br>        mi++;     /* Death is another wave */
 <img src=\"p%s%d%d.gif\">",strtok(optionfile, "."),cpt,j1,strtok(optionfile, "."),cpt,j1);        /* if(mi==0)  never been interviewed correctly before death */
        }           /* Only death is a correct wave */
     for(cpt=1; cpt<=nlstate;cpt++) {        mw[mi][i]=m;
        fprintf(fichtm,"<br>- Observed and stationary prevalence (with confident      }
 interval) in state (%d): v%s%d%d.gif <br>  
 <img src=\"v%s%d%d.gif\">",cpt,strtok(optionfile, "."),cpt,j1,strtok(optionfile, "."),cpt,j1);        wav[i]=mi;
      }      if(mi==0){
      for(cpt=1; cpt<=nlstate;cpt++) {        nbwarn++;
         fprintf(fichtm,"\n<br>- Health life expectancies by age and initial health state (%d): exp%s%d%d.gif <br>        if(first==0){
 <img src=\"exp%s%d%d.gif\">",cpt,strtok(optionfile, "."),cpt,j1,strtok(optionfile, "."),cpt,j1);          printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
      }          first=1;
      fprintf(fichtm,"\n<br>- Total life expectancy by age and        }
 health expectancies in states (1) and (2): e%s%d.gif<br>        if(first==1){
 <img src=\"e%s%d.gif\">",strtok(optionfile, "."),j1,strtok(optionfile, "."),j1);          fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
 fprintf(fichtm,"\n</body>");        }
    }      } /* end mi==0 */
  }    } /* End individuals */
 fclose(fichtm);  
     for(i=1; i<=imx; i++){
   /*--------------- Prevalence limit --------------*/      for(mi=1; mi<wav[i];mi++){
          if (stepm <=0)
   strcpy(filerespl,"pl");          dh[mi][i]=1;
   strcat(filerespl,fileres);        else{
   if((ficrespl=fopen(filerespl,"w"))==NULL) {          if (s[mw[mi+1][i]][i] > nlstate) { /* A death */
     printf("Problem with Prev limit resultfile: %s\n", filerespl);goto end;            if (agedc[i] < 2*AGESUP) {
   }              j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
   printf("Computing prevalence limit: result on file '%s' \n", filerespl);              if(j==0) j=1;  /* Survives at least one month after exam */
   fprintf(ficrespl,"#Prevalence limit\n");              else if(j<0){
   fprintf(ficrespl,"#Age ");                nberr++;
   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);                printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
   fprintf(ficrespl,"\n");                j=1; /* Temporary Dangerous patch */
                  printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
   prlim=matrix(1,nlstate,1,nlstate);                fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */                fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */              }
   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */              k=k+1;
   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */              if (j >= jmax){
   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */                jmax=j;
   k=0;                ijmax=i;
   agebase=agemin;              }
   agelim=agemax;              if (j <= jmin){
   ftolpl=1.e-10;                jmin=j;
   i1=cptcoveff;                ijmin=i;
   if (cptcovn < 1){i1=1;}              }
               sum=sum+j;
   for(cptcov=1;cptcov<=i1;cptcov++){              /*if (j<0) printf("j=%d num=%d \n",j,i);*/
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){              /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
         k=k+1;            }
         /*printf("cptcov=%d cptcod=%d codtab=%d nbcode=%d\n",cptcov, cptcod,Tcode[cptcode],codtab[cptcod][cptcov]);*/          }
         fprintf(ficrespl,"\n#******");          else{
         for(j=1;j<=cptcoveff;j++)            j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
           fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);  /*        if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
         fprintf(ficrespl,"******\n");  
                    k=k+1;
         for (age=agebase; age<=agelim; age++){            if (j >= jmax) {
           prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);              jmax=j;
           fprintf(ficrespl,"%.0f",age );              ijmax=i;
           for(i=1; i<=nlstate;i++)            }
           fprintf(ficrespl," %.5f", prlim[i][i]);            else if (j <= jmin){
           fprintf(ficrespl,"\n");              jmin=j;
         }              ijmin=i;
       }            }
     }            /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
   fclose(ficrespl);            /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
             if(j<0){
   /*------------- h Pij x at various ages ------------*/              nberr++;
                printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
   strcpy(filerespij,"pij");  strcat(filerespij,fileres);              fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
   if((ficrespij=fopen(filerespij,"w"))==NULL) {            }
     printf("Problem with Pij resultfile: %s\n", filerespij);goto end;            sum=sum+j;
   }          }
   printf("Computing pij: result on file '%s' \n", filerespij);          jk= j/stepm;
            jl= j -jk*stepm;
   stepsize=(int) (stepm+YEARM-1)/YEARM;          ju= j -(jk+1)*stepm;
   /*if (stepm<=24) stepsize=2;*/          if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
             if(jl==0){
   agelim=AGESUP;              dh[mi][i]=jk;
   hstepm=stepsize*YEARM; /* Every year of age */              bh[mi][i]=0;
   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */            }else{ /* We want a negative bias in order to only have interpolation ie
                      * to avoid the price of an extra matrix product in likelihood */
   k=0;              dh[mi][i]=jk+1;
   for(cptcov=1;cptcov<=i1;cptcov++){              bh[mi][i]=ju;
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){            }
       k=k+1;          }else{
         fprintf(ficrespij,"\n#****** ");            if(jl <= -ju){
         for(j=1;j<=cptcoveff;j++)              dh[mi][i]=jk;
           fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);              bh[mi][i]=jl;       /* bias is positive if real duration
         fprintf(ficrespij,"******\n");                                   * is higher than the multiple of stepm and negative otherwise.
                                           */
         for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */            }
           nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */            else{
           nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */              dh[mi][i]=jk+1;
           p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);              bh[mi][i]=ju;
           oldm=oldms;savm=savms;            }
           hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);              if(dh[mi][i]==0){
           fprintf(ficrespij,"# Age");              dh[mi][i]=1; /* At least one step */
           for(i=1; i<=nlstate;i++)              bh[mi][i]=ju; /* At least one step */
             for(j=1; j<=nlstate+ndeath;j++)              /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
               fprintf(ficrespij," %1d-%1d",i,j);            }
           fprintf(ficrespij,"\n");          } /* end if mle */
           for (h=0; h<=nhstepm; h++){        }
             fprintf(ficrespij,"%d %.0f %.0f",k,agedeb, agedeb+ h*hstepm/YEARM*stepm );      } /* end wave */
             for(i=1; i<=nlstate;i++)    }
               for(j=1; j<=nlstate+ndeath;j++)    jmean=sum/k;
                 fprintf(ficrespij," %.5f", p3mat[i][j][h]);    printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
             fprintf(ficrespij,"\n");    fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
           }   }
           free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);  
           fprintf(ficrespij,"\n");  /*********** Tricode ****************************/
         }  void tricode(int *Tvar, int **nbcode, int imx, int *Ndum)
     }  {
   }    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
     /*      Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
   /* varprob(fileres, matcov, p, delti, nlstate, (int) bage, (int) fage,k);*/    /* Boring subroutine which should only output nbcode[Tvar[j]][k]
      * Tvar[5] in V2+V1+V3*age+V2*V4 is 2 (V2)
   fclose(ficrespij);    /* nbcode[Tvar[j]][1]= 
     */
   /*---------- Forecasting ------------------*/  
     int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
   strcpy(fileresf,"f");    int modmaxcovj=0; /* Modality max of covariates j */
   strcat(fileresf,fileres);    int cptcode=0; /* Modality max of covariates j */
   if((ficresf=fopen(fileresf,"w"))==NULL) {    int modmincovj=0; /* Modality min of covariates j */
     printf("Problem with forecast resultfile: %s\n", fileresf);goto end;  
   }  
   printf("Computing forecasting: result on file '%s' \n", fileresf);    cptcoveff=0; 
    
   /* Mobile average */    for (k=-1; k < maxncov; k++) Ndum[k]=0;
     for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
   /* for (agedeb=bage; agedeb<=fage; agedeb++)  
     for (i=1; i<=nlstate;i++)    /* Loop on covariates without age and products */
       for (cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++)    for (j=1; j<=(cptcovs); j++) { /* model V1 + V2*age+ V3 + V3*V4 : V1 + V3 = 2 only */
       printf("%f %d i=%d j1=%d\n", probs[(int)agedeb][i][cptcod],(int) agedeb,i,cptcod);*/      for (i=1; i<=imx; i++) { /* Lopp on individuals: reads the data file to get the maximum value of the 
                                  modality of this covariate Vj*/ 
   if (cptcoveff==0) ncodemax[cptcoveff]=1;        ij=(int)(covar[Tvar[j]][i]); /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                                       * If product of Vn*Vm, still boolean *:
   if (mobilav==1) {                                      * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
     mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);                                      * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
     for (agedeb=bage+3; agedeb<=fage-2; agedeb++)        /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
       for (i=1; i<=nlstate;i++)                                        modality of the nth covariate of individual i. */
         for (cptcod=1;cptcod<=ncodemax[cptcov];cptcod++)        if (ij > modmaxcovj)
           mobaverage[(int)agedeb][i][cptcod]=0.;          modmaxcovj=ij; 
            else if (ij < modmincovj) 
     for (agedeb=bage+4; agedeb<=fage; agedeb++){          modmincovj=ij; 
       for (i=1; i<=nlstate;i++){        if ((ij < -1) && (ij > NCOVMAX)){
         for (cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){          printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
           for (cpt=0;cpt<=4;cpt++){          exit(1);
             mobaverage[(int)agedeb-2][i][cptcod]=mobaverage[(int)agedeb-2][i][cptcod]+probs[(int)agedeb-cpt][i][cptcod];        }else
           }        Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
           mobaverage[(int)agedeb-2][i][cptcod]=mobaverage[(int)agedeb-2][i][cptcod]/5;        /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
         }        /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
       }        /* getting the maximum value of the modality of the covariate
     }             (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
   }           female is 1, then modmaxcovj=1.*/
       }
   stepsize=(int) (stepm+YEARM-1)/YEARM;      printf(" Minimal and maximal values of %d th covariate V%d: min=%d max=%d \n", j, Tvar[j], modmincovj, modmaxcovj);
   if (stepm<=24) stepsize=2;      cptcode=modmaxcovj;
       /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
   agelim=AGESUP;     /*for (i=0; i<=cptcode; i++) {*/
   hstepm=stepsize*YEARM; /* Every year of age */      for (i=modmincovj;  i<=modmaxcovj; i++) { /* i=-1 ? 0 and 1*//* For each value of the modality of model-cov j */
   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */        printf("Frequencies of covariates %d V%d %d\n", j, Tvar[j], Ndum[i]);
   hstepm=12;        if( Ndum[i] != 0 ){ /* Counts if nobody answered, empty modality */
    k=0;          ncodemax[j]++;  /* ncodemax[j]= Number of non-null modalities of the j th covariate. */
   for(cptcov=1;cptcov<=i1;cptcov++){        }
     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){        /* In fact  ncodemax[j]=2 (dichotom. variables only) but it could be more for
       k=k+1;           historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
       fprintf(ficresf,"\n#****** ");      } /* Ndum[-1] number of undefined modalities */
       for(j=1;j<=cptcoveff;j++) {  
         fprintf(ficresf,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);      /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
       }      /* For covariate j, modalities could be 1, 2, 3, 4. If Ndum[2]=0 ncodemax[j] is not 4 but 3 */
            /* If Ndum[3}= 635; Ndum[4]=0; Ndum[5]=0; Ndum[6]=27; Ndum[7]=125;
       fprintf(ficresf,"******\n");         modmincovj=3; modmaxcovj = 7;
          There are only 3 modalities non empty (or 2 if 27 is too few) : ncodemax[j]=3;
       fprintf(ficresf,"# StartingAge FinalAge Horizon(in years)");         which will be coded 0, 1, 2 which in binary on 3-1 digits are 0=00 1=01, 2=10; defining two dummy 
       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficresf," P.%d",j);         variables V1_1 and V1_2.
          nbcode[Tvar[j]][ij]=k;
       for (agedeb=fage; agedeb>=bage; agedeb--){         nbcode[Tvar[j]][1]=0;
         fprintf(ficresf,"\n%d %.f %.f 0 ",k,agedeb, agedeb);         nbcode[Tvar[j]][2]=1;
        if (mobilav==1) {         nbcode[Tvar[j]][3]=2;
         for(j=1; j<=nlstate;j++)      */
           fprintf(ficresf,"%.5f ",mobaverage[(int)agedeb][j][cptcod]);      ij=1; /* ij is similar to i but can jumps over null modalities */
         }      for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 */
         else {        for (k=0; k<= cptcode; k++) { /* k=-1 ? k=0 to 1 *//* Could be 1 to 4 */
           for(j=1; j<=nlstate;j++)          /*recode from 0 */
           fprintf(ficresf,"%.5f ",probs[(int)agedeb][j][cptcod]);          if (Ndum[k] != 0) { /* If at least one individual responded to this modality k */
         }            nbcode[Tvar[j]][ij]=k;  /* stores the modality in an array nbcode. 
                                               k is a modality. If we have model=V1+V1*sex 
       for(j=1; j<=ndeath;j++) fprintf(ficresf,"0.");                                       then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
       }            ij++;
       for (cpt=1; cpt<=NCOVMAX;cpt++)            }
       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */          if (ij > ncodemax[j]) break; 
                }  /* end of loop on */
         nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */      } /* end of loop on modality */ 
         nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
         /*printf("stepm=%d hstepm=%d nhstepm=%d \n",stepm,hstepm,nhstepm);*/    
    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
         p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);    
         oldm=oldms;savm=savms;    for (i=1; i<=ncovmodel-2; i++) { /* -2, cste and age */ 
         hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);       /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                     ij=Tvar[i]; /* Tvar might be -1 if status was unknown */ 
         for (h=0; h<=nhstepm; h++){     Ndum[ij]++; 
           } 
           if (h*hstepm/YEARM*stepm==cpt)  
  fprintf(ficresf,"\n%d %.f %.f %.f",k,agedeb, agedeb+ h*hstepm/YEARM*stepm, h*hstepm/YEARM*stepm);   ij=1;
             for (i=0; i<=  maxncov-1; i++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
           for(j=1; j<=nlstate+ndeath;j++) {     /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
             kk1=0.;     if((Ndum[i]!=0) && (i<=ncovcol)){
             for(i=1; i<=nlstate;i++) {               /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
               if (mobilav==1)       Tvaraff[ij]=i; /*For printing (unclear) */
               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb][i][cptcod];       ij++;
               else kk1=kk1+p3mat[i][j][h]*probs[(int)agedeb][i][cptcod];     }else
             }             Tvaraff[ij]=0;
             if (h*hstepm/YEARM*stepm==cpt) fprintf(ficresf," %.5f ", kk1);   }
           }   ij--;
         }   cptcoveff=ij; /*Number of total covariates*/
         free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);  
       }  }
     }  
   }  
   if (mobilav==1) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);  /*********** Health Expectancies ****************/
   fclose(ficresf);  
   /*---------- Health expectancies and variances ------------*/  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[] )
   
   strcpy(filerest,"t");  {
   strcat(filerest,fileres);    /* Health expectancies, no variances */
   if((ficrest=fopen(filerest,"w"))==NULL) {    int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2;
     printf("Problem with total LE resultfile: %s\n", filerest);goto end;    int nhstepma, nstepma; /* Decreasing with age */
   }    double age, agelim, hf;
   printf("Computing Total LEs with variances: file '%s' \n", filerest);    double ***p3mat;
     double eip;
   
   strcpy(filerese,"e");    pstamp(ficreseij);
   strcat(filerese,fileres);    fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
   if((ficreseij=fopen(filerese,"w"))==NULL) {    fprintf(ficreseij,"# Age");
     printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);    for(i=1; i<=nlstate;i++){
   }      for(j=1; j<=nlstate;j++){
   printf("Computing Health Expectancies: result on file '%s' \n", filerese);        fprintf(ficreseij," e%1d%1d ",i,j);
       }
  strcpy(fileresv,"v");      fprintf(ficreseij," e%1d. ",i);
   strcat(fileresv,fileres);    }
   if((ficresvij=fopen(fileresv,"w"))==NULL) {    fprintf(ficreseij,"\n");
     printf("Problem with variance resultfile: %s\n", fileresv);exit(0);  
   }    
   printf("Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);    if(estepm < stepm){
       printf ("Problem %d lower than %d\n",estepm, stepm);
   k=0;    }
   for(cptcov=1;cptcov<=i1;cptcov++){    else  hstepm=estepm;   
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){    /* We compute the life expectancy from trapezoids spaced every estepm months
       k=k+1;     * This is mainly to measure the difference between two models: for example
       fprintf(ficrest,"\n#****** ");     * if stepm=24 months pijx are given only every 2 years and by summing them
       for(j=1;j<=cptcoveff;j++)     * we are calculating an estimate of the Life Expectancy assuming a linear 
         fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);     * progression in between and thus overestimating or underestimating according
       fprintf(ficrest,"******\n");     * to the curvature of the survival function. If, for the same date, we 
      * estimate the model with stepm=1 month, we can keep estepm to 24 months
       fprintf(ficreseij,"\n#****** ");     * to compare the new estimate of Life expectancy with the same linear 
       for(j=1;j<=cptcoveff;j++)     * hypothesis. A more precise result, taking into account a more precise
         fprintf(ficreseij,"V%d=%d ",j,nbcode[j][codtab[k][j]]);     * curvature will be obtained if estepm is as small as stepm. */
       fprintf(ficreseij,"******\n");  
     /* For example we decided to compute the life expectancy with the smallest unit */
       fprintf(ficresvij,"\n#****** ");    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
       for(j=1;j<=cptcoveff;j++)       nhstepm is the number of hstepm from age to agelim 
         fprintf(ficresvij,"V%d=%d ",j,nbcode[j][codtab[k][j]]);       nstepm is the number of stepm from age to agelin. 
       fprintf(ficresvij,"******\n");       Look at hpijx to understand the reason of that which relies in memory size
        and note for a fixed period like estepm months */
       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);    /* We decided (b) to get a life expectancy respecting the most precise curvature of the
       oldm=oldms;savm=savms;       survival function given by stepm (the optimization length). Unfortunately it
       evsij(fileres, eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k);         means that if the survival funtion is printed only each two years of age and if
       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
       oldm=oldms;savm=savms;       results. So we changed our mind and took the option of the best precision.
       varevsij(fileres, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k);    */
          hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
       fprintf(ficrest,"#Total LEs with variances: e.. (std) ");  
       for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);    agelim=AGESUP;
       fprintf(ficrest,"\n");    /* If stepm=6 months */
              /* Computed by stepm unit matrices, product of hstepm matrices, stored
       hf=1;         in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
       if (stepm >= YEARM) hf=stepm/YEARM;      
       epj=vector(1,nlstate+1);  /* nhstepm age range expressed in number of stepm */
       for(age=bage; age <=fage ;age++){    nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
         prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);    /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
         if (popbased==1) {    /* if (stepm >= YEARM) hstepm=1;*/
           for(i=1; i<=nlstate;i++)    nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
             prlim[i][i]=probs[(int)age][i][k];    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
         }  
            for (age=bage; age<=fage; age ++){ 
         fprintf(ficrest," %.0f",age);      nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
         for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){      /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
           for(i=1, epj[j]=0.;i <=nlstate;i++) {      /* if (stepm >= YEARM) hstepm=1;*/
             epj[j] += prlim[i][i]*hf*eij[i][j][(int)age];      nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
           }  
           epj[nlstate+1] +=epj[j];      /* If stepm=6 months */
         }      /* Computed by stepm unit matrices, product of hstepma matrices, stored
         for(i=1, vepp=0.;i <=nlstate;i++)         in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
           for(j=1;j <=nlstate;j++)      
             vepp += vareij[i][j][(int)age];      hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij);  
         fprintf(ficrest," %.2f (%.2f)", epj[nlstate+1],hf*sqrt(vepp));      
         for(j=1;j <=nlstate;j++){      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
           fprintf(ficrest," %.2f (%.2f)", epj[j],hf*sqrt(vareij[j][j][(int)age]));      
         }      printf("%d|",(int)age);fflush(stdout);
         fprintf(ficrest,"\n");      fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
       }      
     }      /* Computing expectancies */
   }      for(i=1; i<=nlstate;i++)
                for(j=1; j<=nlstate;j++)
                  for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
             eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
             
  fclose(ficreseij);            /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
  fclose(ficresvij);  
   fclose(ficrest);          }
   fclose(ficpar);  
   free_vector(epj,1,nlstate+1);      fprintf(ficreseij,"%3.0f",age );
   /*  scanf("%d ",i); */      for(i=1; i<=nlstate;i++){
         eip=0;
   /*------- Variance limit prevalence------*/          for(j=1; j<=nlstate;j++){
           eip +=eij[i][j][(int)age];
 strcpy(fileresvpl,"vpl");          fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
   strcat(fileresvpl,fileres);        }
   if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {        fprintf(ficreseij,"%9.4f", eip );
     printf("Problem with variance prev lim resultfile: %s\n", fileresvpl);      }
     exit(0);      fprintf(ficreseij,"\n");
   }      
   printf("Computing Variance-covariance of Prevalence limit: file '%s' \n", fileresvpl);    }
     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
  k=0;    printf("\n");
  for(cptcov=1;cptcov<=i1;cptcov++){    fprintf(ficlog,"\n");
    for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){    
      k=k+1;  }
      fprintf(ficresvpl,"\n#****** ");  
      for(j=1;j<=cptcoveff;j++)  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[] )
        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);  
      fprintf(ficresvpl,"******\n");  {
          /* Covariances of health expectancies eij and of total life expectancies according
      varpl=matrix(1,nlstate,(int) bage, (int) fage);     to initial status i, ei. .
      oldm=oldms;savm=savms;    */
      varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k);    int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
    }    int nhstepma, nstepma; /* Decreasing with age */
  }    double age, agelim, hf;
     double ***p3matp, ***p3matm, ***varhe;
   fclose(ficresvpl);    double **dnewm,**doldm;
     double *xp, *xm;
   /*---------- End : free ----------------*/    double **gp, **gm;
   free_matrix(varpl,1,nlstate,(int) bage, (int)fage);    double ***gradg, ***trgradg;
      int theta;
   free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);  
   free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);    double eip, vip;
    
      varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
   free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);    xp=vector(1,npar);
   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);    xm=vector(1,npar);
   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);    dnewm=matrix(1,nlstate*nlstate,1,npar);
   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);    doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
      
   free_matrix(matcov,1,npar,1,npar);    pstamp(ficresstdeij);
   free_vector(delti,1,npar);    fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
      fprintf(ficresstdeij,"# Age");
   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);    for(i=1; i<=nlstate;i++){
       for(j=1; j<=nlstate;j++)
   printf("End of Imach\n");        fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */      fprintf(ficresstdeij," e%1d. ",i);
      }
   /* printf("Total time was %d Sec. %d uSec.\n", end_time.tv_sec -start_time.tv_sec, end_time.tv_usec -start_time.tv_usec);*/    fprintf(ficresstdeij,"\n");
   /*printf("Total time was %d uSec.\n", total_usecs);*/  
   /*------ End -----------*/    pstamp(ficrescveij);
     fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
     fprintf(ficrescveij,"# Age");
  end:    for(i=1; i<=nlstate;i++)
 #ifdef windows      for(j=1; j<=nlstate;j++){
  chdir(pathcd);        cptj= (j-1)*nlstate+i;
 #endif        for(i2=1; i2<=nlstate;i2++)
            for(j2=1; j2<=nlstate;j2++){
  system("..\\gp37mgw\\wgnuplot graph.plt");            cptj2= (j2-1)*nlstate+i2;
             if(cptj2 <= cptj)
 #ifdef windows              fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
   while (z[0] != 'q') {          }
     chdir(pathcd);      }
     printf("\nType e to edit output files, c to start again, and q for exiting: ");    fprintf(ficrescveij,"\n");
     scanf("%s",z);    
     if (z[0] == 'c') system("./imach");    if(estepm < stepm){
     else if (z[0] == 'e') {      printf ("Problem %d lower than %d\n",estepm, stepm);
       chdir(path);    }
       system(optionfilehtm);    else  hstepm=estepm;   
     }    /* We compute the life expectancy from trapezoids spaced every estepm months
     else if (z[0] == 'q') exit(0);     * This is mainly to measure the difference between two models: for example
   }     * if stepm=24 months pijx are given only every 2 years and by summing them
 #endif     * we are calculating an estimate of the Life Expectancy assuming a linear 
 }     * progression in between and thus overestimating or underestimating according
      * to the curvature of the survival function. If, for the same date, we 
      * estimate the model with stepm=1 month, we can keep estepm to 24 months
      * to compare the new estimate of Life expectancy with the same linear 
      * hypothesis. A more precise result, taking into account a more precise
      * curvature will be obtained if estepm is as small as stepm. */
   
     /* For example we decided to compute the life expectancy with the smallest unit */
     /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
        nhstepm is the number of hstepm from age to agelim 
        nstepm is the number of stepm from age to agelin. 
        Look at hpijx to understand the reason of that which relies in memory size
        and note for a fixed period like estepm months */
     /* We decided (b) to get a life expectancy respecting the most precise curvature of the
        survival function given by stepm (the optimization length). Unfortunately it
        means that if the survival funtion is printed only each two years of age and if
        you sum them up and add 1 year (area under the trapezoids) you won't get the same 
        results. So we changed our mind and took the option of the best precision.
     */
     hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
   
     /* If stepm=6 months */
     /* nhstepm age range expressed in number of stepm */
     agelim=AGESUP;
     nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
     /* if (stepm >= YEARM) hstepm=1;*/
     nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
     
     p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
     trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
     gp=matrix(0,nhstepm,1,nlstate*nlstate);
     gm=matrix(0,nhstepm,1,nlstate*nlstate);
   
     for (age=bage; age<=fage; age ++){ 
       nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
       /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
       /* if (stepm >= YEARM) hstepm=1;*/
       nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
   
       /* If stepm=6 months */
       /* Computed by stepm unit matrices, product of hstepma matrices, stored
          in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
       
       hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
   
       /* Computing  Variances of health expectancies */
       /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
          decrease memory allocation */
       for(theta=1; theta <=npar; theta++){
         for(i=1; i<=npar; i++){ 
           xp[i] = x[i] + (i==theta ?delti[theta]:0);
           xm[i] = x[i] - (i==theta ?delti[theta]:0);
         }
         hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij);  
         hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij);  
     
         for(j=1; j<= nlstate; j++){
           for(i=1; i<=nlstate; i++){
             for(h=0; h<=nhstepm-1; h++){
               gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
               gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
             }
           }
         }
        
         for(ij=1; ij<= nlstate*nlstate; ij++)
           for(h=0; h<=nhstepm-1; h++){
             gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
           }
       }/* End theta */
       
       
       for(h=0; h<=nhstepm-1; h++)
         for(j=1; j<=nlstate*nlstate;j++)
           for(theta=1; theta <=npar; theta++)
             trgradg[h][j][theta]=gradg[h][theta][j];
       
   
        for(ij=1;ij<=nlstate*nlstate;ij++)
         for(ji=1;ji<=nlstate*nlstate;ji++)
           varhe[ij][ji][(int)age] =0.;
   
        printf("%d|",(int)age);fflush(stdout);
        fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
        for(h=0;h<=nhstepm-1;h++){
         for(k=0;k<=nhstepm-1;k++){
           matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
           matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
           for(ij=1;ij<=nlstate*nlstate;ij++)
             for(ji=1;ji<=nlstate*nlstate;ji++)
               varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
         }
       }
   
       /* Computing expectancies */
       hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij);  
       for(i=1; i<=nlstate;i++)
         for(j=1; j<=nlstate;j++)
           for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
             eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
             
             /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
   
           }
   
       fprintf(ficresstdeij,"%3.0f",age );
       for(i=1; i<=nlstate;i++){
         eip=0.;
         vip=0.;
         for(j=1; j<=nlstate;j++){
           eip += eij[i][j][(int)age];
           for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
             vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
           fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
         }
         fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
       }
       fprintf(ficresstdeij,"\n");
   
       fprintf(ficrescveij,"%3.0f",age );
       for(i=1; i<=nlstate;i++)
         for(j=1; j<=nlstate;j++){
           cptj= (j-1)*nlstate+i;
           for(i2=1; i2<=nlstate;i2++)
             for(j2=1; j2<=nlstate;j2++){
               cptj2= (j2-1)*nlstate+i2;
               if(cptj2 <= cptj)
                 fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
             }
         }
       fprintf(ficrescveij,"\n");
      
     }
     free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
     free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
     free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
     free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
     free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     printf("\n");
     fprintf(ficlog,"\n");
   
     free_vector(xm,1,npar);
     free_vector(xp,1,npar);
     free_matrix(dnewm,1,nlstate*nlstate,1,npar);
     free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
     free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
   }
   
   /************ Variance ******************/
   void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[])
   {
     /* Variance of health expectancies */
     /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
     /* double **newm;*/
     double **dnewm,**doldm;
     double **dnewmp,**doldmp;
     int i, j, nhstepm, hstepm, h, nstepm ;
     int k, cptcode;
     double *xp;
     double **gp, **gm;  /* for var eij */
     double ***gradg, ***trgradg; /*for var eij */
     double **gradgp, **trgradgp; /* for var p point j */
     double *gpp, *gmp; /* for var p point j */
     double **varppt; /* for var p point j nlstate to nlstate+ndeath */
     double ***p3mat;
     double age,agelim, hf;
     double ***mobaverage;
     int theta;
     char digit[4];
     char digitp[25];
   
     char fileresprobmorprev[FILENAMELENGTH];
   
     if(popbased==1){
       if(mobilav!=0)
         strcpy(digitp,"-populbased-mobilav-");
       else strcpy(digitp,"-populbased-nomobil-");
     }
     else 
       strcpy(digitp,"-stablbased-");
   
     if (mobilav!=0) {
       mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){
         fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
         printf(" Error in movingaverage mobilav=%d\n",mobilav);
       }
     }
   
     strcpy(fileresprobmorprev,"prmorprev"); 
     sprintf(digit,"%-d",ij);
     /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
     strcat(fileresprobmorprev,digit); /* Tvar to be done */
     strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
     strcat(fileresprobmorprev,fileres);
     if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
       printf("Problem with resultfile: %s\n", fileresprobmorprev);
       fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
     }
     printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
    
     fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
     pstamp(ficresprobmorprev);
     fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
     fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
     for(j=nlstate+1; j<=(nlstate+ndeath);j++){
       fprintf(ficresprobmorprev," p.%-d SE",j);
       for(i=1; i<=nlstate;i++)
         fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
     }  
     fprintf(ficresprobmorprev,"\n");
     fprintf(ficgp,"\n# Routine varevsij");
     /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
     fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
     fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
   /*   } */
     varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
     pstamp(ficresvij);
     fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
     if(popbased==1)
       fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
     else
       fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
     fprintf(ficresvij,"# Age");
     for(i=1; i<=nlstate;i++)
       for(j=1; j<=nlstate;j++)
         fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
     fprintf(ficresvij,"\n");
   
     xp=vector(1,npar);
     dnewm=matrix(1,nlstate,1,npar);
     doldm=matrix(1,nlstate,1,nlstate);
     dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
     doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
   
     gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
     gpp=vector(nlstate+1,nlstate+ndeath);
     gmp=vector(nlstate+1,nlstate+ndeath);
     trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
     
     if(estepm < stepm){
       printf ("Problem %d lower than %d\n",estepm, stepm);
     }
     else  hstepm=estepm;   
     /* For example we decided to compute the life expectancy with the smallest unit */
     /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
        nhstepm is the number of hstepm from age to agelim 
        nstepm is the number of stepm from age to agelin. 
        Look at function hpijx to understand why (it is linked to memory size questions) */
     /* We decided (b) to get a life expectancy respecting the most precise curvature of the
        survival function given by stepm (the optimization length). Unfortunately it
        means that if the survival funtion is printed every two years of age and if
        you sum them up and add 1 year (area under the trapezoids) you won't get the same 
        results. So we changed our mind and took the option of the best precision.
     */
     hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
     agelim = AGESUP;
     for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
       nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
       nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
       gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
       gp=matrix(0,nhstepm,1,nlstate);
       gm=matrix(0,nhstepm,1,nlstate);
   
   
       for(theta=1; theta <=npar; theta++){
         for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
           xp[i] = x[i] + (i==theta ?delti[theta]:0);
         }
         hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);  
         prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);
   
         if (popbased==1) {
           if(mobilav ==0){
             for(i=1; i<=nlstate;i++)
               prlim[i][i]=probs[(int)age][i][ij];
           }else{ /* mobilav */ 
             for(i=1; i<=nlstate;i++)
               prlim[i][i]=mobaverage[(int)age][i][ij];
           }
         }
     
         for(j=1; j<= nlstate; j++){
           for(h=0; h<=nhstepm; h++){
             for(i=1, gp[h][j]=0.;i<=nlstate;i++)
               gp[h][j] += prlim[i][i]*p3mat[i][j][h];
           }
         }
         /* This for computing probability of death (h=1 means
            computed over hstepm matrices product = hstepm*stepm months) 
            as a weighted average of prlim.
         */
         for(j=nlstate+1;j<=nlstate+ndeath;j++){
           for(i=1,gpp[j]=0.; i<= nlstate; i++)
             gpp[j] += prlim[i][i]*p3mat[i][j][1];
         }    
         /* end probability of death */
   
         for(i=1; i<=npar; i++) /* Computes gradient x - delta */
           xp[i] = x[i] - (i==theta ?delti[theta]:0);
         hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);  
         prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);
    
         if (popbased==1) {
           if(mobilav ==0){
             for(i=1; i<=nlstate;i++)
               prlim[i][i]=probs[(int)age][i][ij];
           }else{ /* mobilav */ 
             for(i=1; i<=nlstate;i++)
               prlim[i][i]=mobaverage[(int)age][i][ij];
           }
         }
   
         for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
           for(h=0; h<=nhstepm; h++){
             for(i=1, gm[h][j]=0.;i<=nlstate;i++)
               gm[h][j] += prlim[i][i]*p3mat[i][j][h];
           }
         }
         /* This for computing probability of death (h=1 means
            computed over hstepm matrices product = hstepm*stepm months) 
            as a weighted average of prlim.
         */
         for(j=nlstate+1;j<=nlstate+ndeath;j++){
           for(i=1,gmp[j]=0.; i<= nlstate; i++)
            gmp[j] += prlim[i][i]*p3mat[i][j][1];
         }    
         /* end probability of death */
   
         for(j=1; j<= nlstate; j++) /* vareij */
           for(h=0; h<=nhstepm; h++){
             gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
           }
   
         for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
           gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
         }
   
       } /* End theta */
   
       trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
   
       for(h=0; h<=nhstepm; h++) /* veij */
         for(j=1; j<=nlstate;j++)
           for(theta=1; theta <=npar; theta++)
             trgradg[h][j][theta]=gradg[h][theta][j];
   
       for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
         for(theta=1; theta <=npar; theta++)
           trgradgp[j][theta]=gradgp[theta][j];
     
   
       hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
       for(i=1;i<=nlstate;i++)
         for(j=1;j<=nlstate;j++)
           vareij[i][j][(int)age] =0.;
   
       for(h=0;h<=nhstepm;h++){
         for(k=0;k<=nhstepm;k++){
           matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
           matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
           for(i=1;i<=nlstate;i++)
             for(j=1;j<=nlstate;j++)
               vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
         }
       }
     
       /* pptj */
       matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
       matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
       for(j=nlstate+1;j<=nlstate+ndeath;j++)
         for(i=nlstate+1;i<=nlstate+ndeath;i++)
           varppt[j][i]=doldmp[j][i];
       /* end ppptj */
       /*  x centered again */
       hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij);  
       prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ij);
    
       if (popbased==1) {
         if(mobilav ==0){
           for(i=1; i<=nlstate;i++)
             prlim[i][i]=probs[(int)age][i][ij];
         }else{ /* mobilav */ 
           for(i=1; i<=nlstate;i++)
             prlim[i][i]=mobaverage[(int)age][i][ij];
         }
       }
                
       /* This for computing probability of death (h=1 means
          computed over hstepm (estepm) matrices product = hstepm*stepm months) 
          as a weighted average of prlim.
       */
       for(j=nlstate+1;j<=nlstate+ndeath;j++){
         for(i=1,gmp[j]=0.;i<= nlstate; i++) 
           gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
       }    
       /* end probability of death */
   
       fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
       for(j=nlstate+1; j<=(nlstate+ndeath);j++){
         fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
         for(i=1; i<=nlstate;i++){
           fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
         }
       } 
       fprintf(ficresprobmorprev,"\n");
   
       fprintf(ficresvij,"%.0f ",age );
       for(i=1; i<=nlstate;i++)
         for(j=1; j<=nlstate;j++){
           fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
         }
       fprintf(ficresvij,"\n");
       free_matrix(gp,0,nhstepm,1,nlstate);
       free_matrix(gm,0,nhstepm,1,nlstate);
       free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
       free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     } /* End age */
     free_vector(gpp,nlstate+1,nlstate+ndeath);
     free_vector(gmp,nlstate+1,nlstate+ndeath);
     free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
     free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
     fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240");
     /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
     fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
   /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
   /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
   /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
     fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
     fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95\%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
     fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
     fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
     fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.png\"> <br>\n", estepm,subdirf3(optionfilefiname,"varmuptjgr",digitp),digit);
     /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.png\"> <br>\n", stepm,YEARM,digitp,digit);
   */
   /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.png\";replot;",digitp,optionfilefiname,digit); */
     fprintf(ficgp,"\nset out \"%s%s.png\";replot;\n",subdirf3(optionfilefiname,"varmuptjgr",digitp),digit);
   
     free_vector(xp,1,npar);
     free_matrix(doldm,1,nlstate,1,nlstate);
     free_matrix(dnewm,1,nlstate,1,npar);
     free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
     free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
     free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
     if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     fclose(ficresprobmorprev);
     fflush(ficgp);
     fflush(fichtm); 
   }  /* end varevsij */
   
   /************ Variance of prevlim ******************/
   void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij, char strstart[])
   {
     /* Variance of prevalence limit */
     /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
     double **newm;
     double **dnewm,**doldm;
     int i, j, nhstepm, hstepm;
     int k, cptcode;
     double *xp;
     double *gp, *gm;
     double **gradg, **trgradg;
     double age,agelim;
     int theta;
     
     pstamp(ficresvpl);
     fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
     fprintf(ficresvpl,"# Age");
     for(i=1; i<=nlstate;i++)
         fprintf(ficresvpl," %1d-%1d",i,i);
     fprintf(ficresvpl,"\n");
   
     xp=vector(1,npar);
     dnewm=matrix(1,nlstate,1,npar);
     doldm=matrix(1,nlstate,1,nlstate);
     
     hstepm=1*YEARM; /* Every year of age */
     hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
     agelim = AGESUP;
     for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
       nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
       if (stepm >= YEARM) hstepm=1;
       nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
       gradg=matrix(1,npar,1,nlstate);
       gp=vector(1,nlstate);
       gm=vector(1,nlstate);
   
       for(theta=1; theta <=npar; theta++){
         for(i=1; i<=npar; i++){ /* Computes gradient */
           xp[i] = x[i] + (i==theta ?delti[theta]:0);
         }
         prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);
         for(i=1;i<=nlstate;i++)
           gp[i] = prlim[i][i];
       
         for(i=1; i<=npar; i++) /* Computes gradient */
           xp[i] = x[i] - (i==theta ?delti[theta]:0);
         prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);
         for(i=1;i<=nlstate;i++)
           gm[i] = prlim[i][i];
   
         for(i=1;i<=nlstate;i++)
           gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
       } /* End theta */
   
       trgradg =matrix(1,nlstate,1,npar);
   
       for(j=1; j<=nlstate;j++)
         for(theta=1; theta <=npar; theta++)
           trgradg[j][theta]=gradg[theta][j];
   
       for(i=1;i<=nlstate;i++)
         varpl[i][(int)age] =0.;
       matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
       matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
       for(i=1;i<=nlstate;i++)
         varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
   
       fprintf(ficresvpl,"%.0f ",age );
       for(i=1; i<=nlstate;i++)
         fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
       fprintf(ficresvpl,"\n");
       free_vector(gp,1,nlstate);
       free_vector(gm,1,nlstate);
       free_matrix(gradg,1,npar,1,nlstate);
       free_matrix(trgradg,1,nlstate,1,npar);
     } /* End age */
   
     free_vector(xp,1,npar);
     free_matrix(doldm,1,nlstate,1,npar);
     free_matrix(dnewm,1,nlstate,1,nlstate);
   
   }
   
   /************ Variance of one-step probabilities  ******************/
   void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
   {
     int i, j=0,  i1, k1, l1, t, tj;
     int k2, l2, j1,  z1;
     int k=0,l, cptcode;
     int first=1, first1, first2;
     double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
     double **dnewm,**doldm;
     double *xp;
     double *gp, *gm;
     double **gradg, **trgradg;
     double **mu;
     double age,agelim, cov[NCOVMAX+1];
     double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
     int theta;
     char fileresprob[FILENAMELENGTH];
     char fileresprobcov[FILENAMELENGTH];
     char fileresprobcor[FILENAMELENGTH];
     double ***varpij;
   
     strcpy(fileresprob,"prob"); 
     strcat(fileresprob,fileres);
     if((ficresprob=fopen(fileresprob,"w"))==NULL) {
       printf("Problem with resultfile: %s\n", fileresprob);
       fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
     }
     strcpy(fileresprobcov,"probcov"); 
     strcat(fileresprobcov,fileres);
     if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
       printf("Problem with resultfile: %s\n", fileresprobcov);
       fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
     }
     strcpy(fileresprobcor,"probcor"); 
     strcat(fileresprobcor,fileres);
     if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
       printf("Problem with resultfile: %s\n", fileresprobcor);
       fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
     }
     printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
     fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
     printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
     fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
     printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
     fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
     pstamp(ficresprob);
     fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
     fprintf(ficresprob,"# Age");
     pstamp(ficresprobcov);
     fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
     fprintf(ficresprobcov,"# Age");
     pstamp(ficresprobcor);
     fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
     fprintf(ficresprobcor,"# Age");
   
   
     for(i=1; i<=nlstate;i++)
       for(j=1; j<=(nlstate+ndeath);j++){
         fprintf(ficresprob," p%1d-%1d (SE)",i,j);
         fprintf(ficresprobcov," p%1d-%1d ",i,j);
         fprintf(ficresprobcor," p%1d-%1d ",i,j);
       }  
    /* fprintf(ficresprob,"\n");
     fprintf(ficresprobcov,"\n");
     fprintf(ficresprobcor,"\n");
    */
     xp=vector(1,npar);
     dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
     doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
     mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
     varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
     first=1;
     fprintf(ficgp,"\n# Routine varprob");
     fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
     fprintf(fichtm,"\n");
   
     fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of pairs of step probabilities (drawings)</a></h4></li>\n",optionfilehtmcov);
     fprintf(fichtmcov,"\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n\
     file %s<br>\n",optionfilehtmcov);
     fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated\
   and drawn. It helps understanding how is the covariance between two incidences.\
    They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
     fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
   It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
   would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
   standard deviations wide on each axis. <br>\
    Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
    and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
   To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
   
     cov[1]=1;
     /* tj=cptcoveff; */
     tj = (int) pow(2,cptcoveff);
     if (cptcovn<1) {tj=1;ncodemax[1]=1;}
     j1=0;
     for(j1=1; j1<=tj;j1++){
       /*for(i1=1; i1<=ncodemax[t];i1++){ */
       /*j1++;*/
         if  (cptcovn>0) {
           fprintf(ficresprob, "\n#********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
           fprintf(ficresprob, "**********\n#\n");
           fprintf(ficresprobcov, "\n#********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
           fprintf(ficresprobcov, "**********\n#\n");
           
           fprintf(ficgp, "\n#********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
           fprintf(ficgp, "**********\n#\n");
           
           
           fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
           fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
           
           fprintf(ficresprobcor, "\n#********** Variable ");    
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
           fprintf(ficresprobcor, "**********\n#");    
         }
         
         gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
         trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
         gp=vector(1,(nlstate)*(nlstate+ndeath));
         gm=vector(1,(nlstate)*(nlstate+ndeath));
         for (age=bage; age<=fage; age ++){ 
           cov[2]=age;
           for (k=1; k<=cptcovn;k++) {
             cov[2+k]=nbcode[Tvar[k]][codtab[j1][Tvar[k]]];/* j1 1 2 3 4
                                                            * 1  1 1 1 1
                                                            * 2  2 1 1 1
                                                            * 3  1 2 1 1
                                                            */
             /* nbcode[1][1]=0 nbcode[1][2]=1;*/
           }
           for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];
           for (k=1; k<=cptcovprod;k++)
             cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];
           
       
           for(theta=1; theta <=npar; theta++){
             for(i=1; i<=npar; i++)
               xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
             
             pmij(pmmij,cov,ncovmodel,xp,nlstate);
             
             k=0;
             for(i=1; i<= (nlstate); i++){
               for(j=1; j<=(nlstate+ndeath);j++){
                 k=k+1;
                 gp[k]=pmmij[i][j];
               }
             }
             
             for(i=1; i<=npar; i++)
               xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
       
             pmij(pmmij,cov,ncovmodel,xp,nlstate);
             k=0;
             for(i=1; i<=(nlstate); i++){
               for(j=1; j<=(nlstate+ndeath);j++){
                 k=k+1;
                 gm[k]=pmmij[i][j];
               }
             }
        
             for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
               gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
           }
   
           for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
             for(theta=1; theta <=npar; theta++)
               trgradg[j][theta]=gradg[theta][j];
           
           matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
           matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
   
           pmij(pmmij,cov,ncovmodel,x,nlstate);
           
           k=0;
           for(i=1; i<=(nlstate); i++){
             for(j=1; j<=(nlstate+ndeath);j++){
               k=k+1;
               mu[k][(int) age]=pmmij[i][j];
             }
           }
           for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
             for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
               varpij[i][j][(int)age] = doldm[i][j];
   
           /*printf("\n%d ",(int)age);
             for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
             printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
             fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
             }*/
   
           fprintf(ficresprob,"\n%d ",(int)age);
           fprintf(ficresprobcov,"\n%d ",(int)age);
           fprintf(ficresprobcor,"\n%d ",(int)age);
   
           for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
             fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
           for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
             fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
             fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
           }
           i=0;
           for (k=1; k<=(nlstate);k++){
             for (l=1; l<=(nlstate+ndeath);l++){ 
               i++;
               fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
               fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
               for (j=1; j<=i;j++){
                 /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                 fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                 fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
               }
             }
           }/* end of loop for state */
         } /* end of loop for age */
         free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
         free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
         free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
         free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
         
         /* Confidence intervalle of pij  */
         /*
           fprintf(ficgp,"\nunset parametric;unset label");
           fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
           fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
           fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
           fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
           fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
           fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
         */
   
         /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
         first1=1;first2=2;
         for (k2=1; k2<=(nlstate);k2++){
           for (l2=1; l2<=(nlstate+ndeath);l2++){ 
             if(l2==k2) continue;
             j=(k2-1)*(nlstate+ndeath)+l2;
             for (k1=1; k1<=(nlstate);k1++){
               for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                 if(l1==k1) continue;
                 i=(k1-1)*(nlstate+ndeath)+l1;
                 if(i<=j) continue;
                 for (age=bage; age<=fage; age ++){ 
                   if ((int)age %5==0){
                     v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                     v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                     cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                     mu1=mu[i][(int) age]/stepm*YEARM ;
                     mu2=mu[j][(int) age]/stepm*YEARM;
                     c12=cv12/sqrt(v1*v2);
                     /* Computing eigen value of matrix of covariance */
                     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                     if ((lc2 <0) || (lc1 <0) ){
                       if(first2==1){
                         first1=0;
                       printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                       }
                       fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                       /* lc1=fabs(lc1); */ /* If we want to have them positive */
                       /* lc2=fabs(lc2); */
                     }
   
                     /* Eigen vectors */
                     v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                     /*v21=sqrt(1.-v11*v11); *//* error */
                     v21=(lc1-v1)/cv12*v11;
                     v12=-v21;
                     v22=v11;
                     tnalp=v21/v11;
                     if(first1==1){
                       first1=0;
                       printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                     }
                     fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                     /*printf(fignu*/
                     /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                     /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                     if(first==1){
                       first=0;
                       fprintf(ficgp,"\nset parametric;unset label");
                       fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                       fprintf(ficgp,"\nset ter png small size 320, 240");
                       fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
    :<a href=\"%s%d%1d%1d-%1d%1d.png\">\
   %s%d%1d%1d-%1d%1d.png</A>, ",k1,l1,k2,l2,\
                               subdirf2(optionfilefiname,"varpijgr"), j1,k1,l1,k2,l2,\
                               subdirf2(optionfilefiname,"varpijgr"), j1,k1,l1,k2,l2);
                       fprintf(fichtmcov,"\n<br><img src=\"%s%d%1d%1d-%1d%1d.png\"> ",subdirf2(optionfilefiname,"varpijgr"), j1,k1,l1,k2,l2);
                       fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                       fprintf(ficgp,"\nset out \"%s%d%1d%1d-%1d%1d.png\"",subdirf2(optionfilefiname,"varpijgr"), j1,k1,l1,k2,l2);
                       fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                       fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                       fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",\
                               mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),\
                               mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                     }else{
                       first=0;
                       fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                       fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                       fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                       fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",\
                               mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),\
                               mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                     }/* if first */
                   } /* age mod 5 */
                 } /* end loop age */
                 fprintf(ficgp,"\nset out \"%s%d%1d%1d-%1d%1d.png\";replot;",subdirf2(optionfilefiname,"varpijgr"), j1,k1,l1,k2,l2);
                 first=1;
               } /*l12 */
             } /* k12 */
           } /*l1 */
         }/* k1 */
         /* } /* loop covariates */
     }
     free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
     free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
     free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
     free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
     free_vector(xp,1,npar);
     fclose(ficresprob);
     fclose(ficresprobcov);
     fclose(ficresprobcor);
     fflush(ficgp);
     fflush(fichtmcov);
   }
   
   
   /******************* Printing html file ***********/
   void printinghtml(char fileres[], char title[], char datafile[], int firstpass, \
                     int lastpass, int stepm, int weightopt, char model[],\
                     int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
                     int popforecast, int estepm ,\
                     double jprev1, double mprev1,double anprev1, \
                     double jprev2, double mprev2,double anprev2){
     int jj1, k1, i1, cpt;
   
      fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
      <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
   </ul>");
      fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n \
    - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> <br>\n ",
              jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirf2(fileres,"p"),subdirf2(fileres,"p"));
      fprintf(fichtm,"\
    - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
              stepm,subdirf2(fileres,"pij"),subdirf2(fileres,"pij"));
      fprintf(fichtm,"\
    - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
              subdirf2(fileres,"pl"),subdirf2(fileres,"pl"));
      fprintf(fichtm,"\
    - (a) Life expectancies by health status at initial age, ei. (b) health expectancies by health status at initial age, eij . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
      <a href=\"%s\">%s</a> <br>\n",
              estepm,subdirf2(fileres,"e"),subdirf2(fileres,"e"));
      fprintf(fichtm,"\
    - Population projections by age and states: \
      <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileres,"f"),subdirf2(fileres,"f"));
   
   fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
   
    m=pow(2,cptcoveff);
    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
   
    jj1=0;
    for(k1=1; k1<=m;k1++){
      for(i1=1; i1<=ncodemax[k1];i1++){
        jj1++;
        if (cptcovn > 0) {
          fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
          for (cpt=1; cpt<=cptcoveff;cpt++) 
            fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtab[jj1][cpt]]);
          fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
        }
        /* Pij */
        fprintf(fichtm,"<br>- Pij or Conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s%d_1.png\">%s%d_1.png</a><br> \
   <img src=\"%s%d_1.png\">",stepm,subdirf2(optionfilefiname,"pe"),jj1,subdirf2(optionfilefiname,"pe"),jj1,subdirf2(optionfilefiname,"pe"),jj1);     
        /* Quasi-incidences */
        fprintf(fichtm,"<br>- Pij or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
    before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too: <a href=\"%s%d_2.png\">%s%d_2.png</a><br> \
   <img src=\"%s%d_2.png\">",stepm,subdirf2(optionfilefiname,"pe"),jj1,subdirf2(optionfilefiname,"pe"),jj1,subdirf2(optionfilefiname,"pe"),jj1); 
          /* Period (stable) prevalence in each health state */
          for(cpt=1; cpt<nlstate;cpt++){
            fprintf(fichtm,"<br>- Period (stable) prevalence in each health state : <a href=\"%s%d_%d.png\">%s%d_%d.png</a><br> \
   <img src=\"%s%d_%d.png\">",subdirf2(optionfilefiname,"p"),cpt,jj1,subdirf2(optionfilefiname,"p"),cpt,jj1,subdirf2(optionfilefiname,"p"),cpt,jj1);
          }
        for(cpt=1; cpt<=nlstate;cpt++) {
           fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies : <a href=\"%s%d%d.png\">%s%d%d.png</a> <br> \
   <img src=\"%s%d%d.png\">",cpt,subdirf2(optionfilefiname,"exp"),cpt,jj1,subdirf2(optionfilefiname,"exp"),cpt,jj1,subdirf2(optionfilefiname,"exp"),cpt,jj1);
        }
      } /* end i1 */
    }/* End k1 */
    fprintf(fichtm,"</ul>");
   
   
    fprintf(fichtm,"\
   \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
    - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br>\n", rfileres,rfileres);
   
    fprintf(fichtm," - Variance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
            subdirf2(fileres,"prob"),subdirf2(fileres,"prob"));
    fprintf(fichtm,"\
    - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
            subdirf2(fileres,"probcov"),subdirf2(fileres,"probcov"));
   
    fprintf(fichtm,"\
    - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
            subdirf2(fileres,"probcor"),subdirf2(fileres,"probcor"));
    fprintf(fichtm,"\
    - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
      <a href=\"%s\">%s</a> <br>\n</li>",
              estepm,subdirf2(fileres,"cve"),subdirf2(fileres,"cve"));
    fprintf(fichtm,"\
    - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
      <a href=\"%s\">%s</a> <br>\n</li>",
              estepm,subdirf2(fileres,"stde"),subdirf2(fileres,"stde"));
    fprintf(fichtm,"\
    - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
            estepm, subdirf2(fileres,"v"),subdirf2(fileres,"v"));
    fprintf(fichtm,"\
    - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
            estepm, subdirf2(fileres,"t"),subdirf2(fileres,"t"));
    fprintf(fichtm,"\
    - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
            subdirf2(fileres,"vpl"),subdirf2(fileres,"vpl"));
   
   /*  if(popforecast==1) fprintf(fichtm,"\n */
   /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
   /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
   /*      <br>",fileres,fileres,fileres,fileres); */
   /*  else  */
   /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
    fflush(fichtm);
    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
   
    m=pow(2,cptcoveff);
    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
   
    jj1=0;
    for(k1=1; k1<=m;k1++){
      for(i1=1; i1<=ncodemax[k1];i1++){
        jj1++;
        if (cptcovn > 0) {
          fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
          for (cpt=1; cpt<=cptcoveff;cpt++) 
            fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtab[jj1][cpt]]);
          fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
        }
        for(cpt=1; cpt<=nlstate;cpt++) {
          fprintf(fichtm,"<br>- Observed (cross-sectional) and period (incidence based) \
   prevalence (with 95%% confidence interval) in state (%d): %s%d_%d.png <br>\
   <img src=\"%s%d_%d.png\">",cpt,subdirf2(optionfilefiname,"v"),cpt,jj1,subdirf2(optionfilefiname,"v"),cpt,jj1);  
        }
        fprintf(fichtm,"\n<br>- Total life expectancy by age and \
   health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
   true period expectancies (those weighted with period prevalences are also\
    drawn in addition to the population based expectancies computed using\
    observed and cahotic prevalences: %s%d.png<br>\
   <img src=\"%s%d.png\">",subdirf2(optionfilefiname,"e"),jj1,subdirf2(optionfilefiname,"e"),jj1);
      } /* end i1 */
    }/* End k1 */
    fprintf(fichtm,"</ul>");
    fflush(fichtm);
   }
   
   /******************* Gnuplot file **************/
   void printinggnuplot(char fileres[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
   
     char dirfileres[132],optfileres[132];
     int m0,cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,ij=0,l=0;
     int ng=0;
   /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
   /*     printf("Problem with file %s",optionfilegnuplot); */
   /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
   /*   } */
   
     /*#ifdef windows */
     fprintf(ficgp,"cd \"%s\" \n",pathc);
       /*#endif */
     m=pow(2,cptcoveff);
   
     strcpy(dirfileres,optionfilefiname);
     strcpy(optfileres,"vpl");
    /* 1eme*/
     fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'vpl' files\n");
     for (cpt=1; cpt<= nlstate ; cpt ++) {
       for (k1=1; k1<= m ; k1 ++) { /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
        fprintf(ficgp,"\nset out \"%s%d_%d.png\" \n",subdirf2(optionfilefiname,"v"),cpt,k1);
        fprintf(ficgp,"\n#set out \"v%s%d_%d.png\" \n",optionfilefiname,cpt,k1);
        fprintf(ficgp,"set xlabel \"Age\" \n\
   set ylabel \"Probability\" \n\
   set ter png small size 320, 240\n\
   plot [%.f:%.f] \"%s\" every :::%d::%d u 1:2 \"\%%lf",ageminpar,fage,subdirf2(fileres,"vpl"),k1-1,k1-1);
   
        for (i=1; i<= nlstate ; i ++) {
          if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");
          else        fprintf(ficgp," \%%*lf (\%%*lf)");
        }
        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2+1.96*$3) \"\%%lf",subdirf2(fileres,"vpl"),k1-1,k1-1);
        for (i=1; i<= nlstate ; i ++) {
          if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");
          else fprintf(ficgp," \%%*lf (\%%*lf)");
        } 
        fprintf(ficgp,"\" t\"95\%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2-1.96*$3) \"\%%lf",subdirf2(fileres,"vpl"),k1-1,k1-1); 
        for (i=1; i<= nlstate ; i ++) {
          if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");
          else fprintf(ficgp," \%%*lf (\%%*lf)");
        }  
        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence \" w l lt 2",subdirf2(fileres,"p"),k1-1,k1-1,2+4*(cpt-1));
      }
     }
     /*2 eme*/
     fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files\n");
     for (k1=1; k1<= m ; k1 ++) { 
       fprintf(ficgp,"\nset out \"%s%d.png\" \n",subdirf2(optionfilefiname,"e"),k1);
       fprintf(ficgp,"set ylabel \"Years\" \nset ter png small size 320, 240\nplot [%.f:%.f] ",ageminpar,fage);
       
       for (i=1; i<= nlstate+1 ; i ++) {
         k=2*i;
         fprintf(ficgp,"\"%s\" every :::%d::%d u 1:2 \"\%%lf",subdirf2(fileres,"t"),k1-1,k1-1);
         for (j=1; j<= nlstate+1 ; j ++) {
           if (j==i) fprintf(ficgp," \%%lf (\%%lf)");
           else fprintf(ficgp," \%%*lf (\%%*lf)");
         }   
         if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l ,");
         else fprintf(ficgp,"\" t\"LE in state (%d)\" w l ,",i-1);
         fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2-$3*2) \"\%%lf",subdirf2(fileres,"t"),k1-1,k1-1);
         for (j=1; j<= nlstate+1 ; j ++) {
           if (j==i) fprintf(ficgp," \%%lf (\%%lf)");
           else fprintf(ficgp," \%%*lf (\%%*lf)");
         }   
         fprintf(ficgp,"\" t\"\" w l lt 0,");
         fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2+$3*2) \"\%%lf",subdirf2(fileres,"t"),k1-1,k1-1);
         for (j=1; j<= nlstate+1 ; j ++) {
           if (j==i) fprintf(ficgp," \%%lf (\%%lf)");
           else fprintf(ficgp," \%%*lf (\%%*lf)");
         }   
         if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
         else fprintf(ficgp,"\" t\"\" w l lt 0,");
       }
     }
     
     /*3eme*/
     
     for (k1=1; k1<= m ; k1 ++) { 
       for (cpt=1; cpt<= nlstate ; cpt ++) {
         /*       k=2+nlstate*(2*cpt-2); */
         k=2+(nlstate+1)*(cpt-1);
         fprintf(ficgp,"\nset out \"%s%d%d.png\" \n",subdirf2(optionfilefiname,"exp"),cpt,k1);
         fprintf(ficgp,"set ter png small size 320, 240\n\
   plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileres,"e"),k1-1,k1-1,k,cpt);
         /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
           for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
           fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
           fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
           for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
           fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
           
         */
         for (i=1; i< nlstate ; i ++) {
           fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+i,cpt,i+1);
           /*      fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
           
         } 
         fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+nlstate,cpt);
       }
     }
     
     /* CV preval stable (period) */
     for (k1=1; k1<= m ; k1 ++) { /* For each multivariate if any */
       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
         k=3;
         fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, cov=%d state=%d",k1, cpt);
         fprintf(ficgp,"\nset out \"%s%d_%d.png\" \n",subdirf2(optionfilefiname,"p"),cpt,k1);
         l=(nlstate+ndeath)*(cpt-1)+1;
         fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
   set ter png small size 320, 240\n\
   unset log y\n\
   plot [%.f:%.f]  ", ageminpar, agemaxpar);
         for (i=1; i<= nlstate ; i ++){
           if(i==1)
             fprintf(ficgp,"\"%s\"",subdirf2(fileres,"pij"));
           else
             fprintf(ficgp,", '' ");
           fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l,k+l);
           for (j=1; j<= (nlstate-1) ; j ++)
             fprintf(ficgp,"+$%d",k+l+j);
           fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
         } /* nlstate */
         fprintf(ficgp,"\n");
       } /* end cpt state*/ 
     } /* end covariate */  
     
     /* proba elementaires */
     for(i=1,jk=1; i <=nlstate; i++){
       for(k=1; k <=(nlstate+ndeath); k++){
         if (k != i) {
           for(j=1; j <=ncovmodel; j++){
             fprintf(ficgp,"p%d=%f ",jk,p[jk]);
             jk++; 
             fprintf(ficgp,"\n");
           }
         }
       }
      }
     /*goto avoid;*/
      for(ng=1; ng<=2;ng++){ /* Number of graphics: first is probabilities second is incidence per year*/
        for(jk=1; jk <=m; jk++) {
          fprintf(ficgp,"\nset out \"%s%d_%d.png\" \n",subdirf2(optionfilefiname,"pe"),jk,ng); 
          if (ng==2)
            fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
          else
            fprintf(ficgp,"\nset title \"Probability\"\n");
          fprintf(ficgp,"\nset ter png small size 320, 240\nset log y\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
          i=1;
          for(k2=1; k2<=nlstate; k2++) {
            k3=i;
            for(k=1; k<=(nlstate+ndeath); k++) {
              if (k != k2){
                if(ng==2)
                  fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                else
                  fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                ij=1;/* To be checked else nbcode[0][0] wrong */
                for(j=3; j <=ncovmodel; j++) {
                  /* if(((j-2)==Tage[ij]) &&(ij <=cptcovage)) { /\* Bug valgrind *\/ */
                  /*        /\*fprintf(ficgp,"+p%d*%d*x",i+j-1,nbcode[Tvar[j-2]][codtab[jk][Tvar[j-2]]]);*\/ */
                  /*        ij++; */
                  /* } */
                  /* else */
                    fprintf(ficgp,"+p%d*%d",i+j-1,nbcode[Tvar[j-2]][codtab[jk][j-2]]);
                }
                fprintf(ficgp,")/(1");
                
                for(k1=1; k1 <=nlstate; k1++){   
                  fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                  ij=1;
                  for(j=3; j <=ncovmodel; j++){
                    /* if(((j-2)==Tage[ij]) &&(ij <=cptcovage)) { */
                    /*   fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2,nbcode[Tvar[j-2]][codtab[jk][Tvar[j-2]]]); */
                    /*   ij++; */
                    /* } */
                    /* else */
                      fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2,nbcode[Tvar[j-2]][codtab[jk][j-2]]);
                  }
                  fprintf(ficgp,")");
                }
                fprintf(ficgp,") t \"p%d%d\" ", k2,k);
                if ((k+k2)!= (nlstate*2+ndeath)) fprintf(ficgp,",");
                i=i+ncovmodel;
              }
            } /* end k */
          } /* end k2 */
        } /* end jk */
      } /* end ng */
    avoid:
      fflush(ficgp); 
   }  /* end gnuplot */
   
   
   /*************** Moving average **************/
   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav){
   
     int i, cpt, cptcod;
     int modcovmax =1;
     int mobilavrange, mob;
     double age;
   
     modcovmax=2*cptcoveff;/* Max number of modalities. We suppose 
                              a covariate has 2 modalities */
     if (cptcovn<1) modcovmax=1; /* At least 1 pass */
   
     if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
       if(mobilav==1) mobilavrange=5; /* default */
       else mobilavrange=mobilav;
       for (age=bage; age<=fage; age++)
         for (i=1; i<=nlstate;i++)
           for (cptcod=1;cptcod<=modcovmax;cptcod++)
             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
       /* We keep the original values on the extreme ages bage, fage and for 
          fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
          we use a 5 terms etc. until the borders are no more concerned. 
       */ 
       for (mob=3;mob <=mobilavrange;mob=mob+2){
         for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
           for (i=1; i<=nlstate;i++){
             for (cptcod=1;cptcod<=modcovmax;cptcod++){
               mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                 for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                 }
               mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
             }
           }
         }/* end age */
       }/* end mob */
     }else return -1;
     return 0;
   }/* End movingaverage */
   
   
   /************** Forecasting ******************/
   prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
     /* proj1, year, month, day of starting projection 
        agemin, agemax range of age
        dateprev1 dateprev2 range of dates during which prevalence is computed
        anproj2 year of en of projection (same day and month as proj1).
     */
     int yearp, stepsize, hstepm, nhstepm, j, k, c, cptcod, i, h, i1;
     int *popage;
     double agec; /* generic age */
     double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
     double *popeffectif,*popcount;
     double ***p3mat;
     double ***mobaverage;
     char fileresf[FILENAMELENGTH];
   
     agelim=AGESUP;
     prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
    
     strcpy(fileresf,"f"); 
     strcat(fileresf,fileres);
     if((ficresf=fopen(fileresf,"w"))==NULL) {
       printf("Problem with forecast resultfile: %s\n", fileresf);
       fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
     }
     printf("Computing forecasting: result on file '%s' \n", fileresf);
     fprintf(ficlog,"Computing forecasting: result on file '%s' \n", fileresf);
   
     if (cptcoveff==0) ncodemax[cptcoveff]=1;
   
     if (mobilav!=0) {
       mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){
         fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
         printf(" Error in movingaverage mobilav=%d\n",mobilav);
       }
     }
   
     stepsize=(int) (stepm+YEARM-1)/YEARM;
     if (stepm<=12) stepsize=1;
     if(estepm < stepm){
       printf ("Problem %d lower than %d\n",estepm, stepm);
     }
     else  hstepm=estepm;   
   
     hstepm=hstepm/stepm; 
     yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                                  fractional in yp1 */
     anprojmean=yp;
     yp2=modf((yp1*12),&yp);
     mprojmean=yp;
     yp1=modf((yp2*30.5),&yp);
     jprojmean=yp;
     if(jprojmean==0) jprojmean=1;
     if(mprojmean==0) jprojmean=1;
   
     i1=cptcoveff;
     if (cptcovn < 1){i1=1;}
     
     fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
     
     fprintf(ficresf,"#****** Routine prevforecast **\n");
   
   /*            if (h==(int)(YEARM*yearp)){ */
     for(cptcov=1, k=0;cptcov<=i1;cptcov++){
       for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){
         k=k+1;
         fprintf(ficresf,"\n#******");
         for(j=1;j<=cptcoveff;j++) {
           fprintf(ficresf," V%d=%d, hpijx=probability over h years, hp.jx is weighted by observed prev ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
         }
         fprintf(ficresf,"******\n");
         fprintf(ficresf,"# Covariate valuofcovar yearproj age");
         for(j=1; j<=nlstate+ndeath;j++){ 
           for(i=1; i<=nlstate;i++)              
             fprintf(ficresf," p%d%d",i,j);
           fprintf(ficresf," p.%d",j);
         }
         for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) { 
           fprintf(ficresf,"\n");
           fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
   
           for (agec=fage; agec>=(ageminpar-1); agec--){ 
             nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
             nhstepm = nhstepm/hstepm; 
             p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             oldm=oldms;savm=savms;
             hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k);  
           
             for (h=0; h<=nhstepm; h++){
               if (h*hstepm/YEARM*stepm ==yearp) {
                 fprintf(ficresf,"\n");
                 for(j=1;j<=cptcoveff;j++) 
                   fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
                 fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
               } 
               for(j=1; j<=nlstate+ndeath;j++) {
                 ppij=0.;
                 for(i=1; i<=nlstate;i++) {
                   if (mobilav==1) 
                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod];
                   else {
                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod];
                   }
                   if (h*hstepm/YEARM*stepm== yearp) {
                     fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   }
                 } /* end i */
                 if (h*hstepm/YEARM*stepm==yearp) {
                   fprintf(ficresf," %.3f", ppij);
                 }
               }/* end j */
             } /* end h */
             free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           } /* end agec */
         } /* end yearp */
       } /* end cptcod */
     } /* end  cptcov */
          
     if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
   
     fclose(ficresf);
   }
   
   /************** Forecasting *****not tested NB*************/
   populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){
     
     int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h;
     int *popage;
     double calagedatem, agelim, kk1, kk2;
     double *popeffectif,*popcount;
     double ***p3mat,***tabpop,***tabpopprev;
     double ***mobaverage;
     char filerespop[FILENAMELENGTH];
   
     tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     agelim=AGESUP;
     calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM;
     
     prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
     
     
     strcpy(filerespop,"pop"); 
     strcat(filerespop,fileres);
     if((ficrespop=fopen(filerespop,"w"))==NULL) {
       printf("Problem with forecast resultfile: %s\n", filerespop);
       fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop);
     }
     printf("Computing forecasting: result on file '%s' \n", filerespop);
     fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop);
   
     if (cptcoveff==0) ncodemax[cptcoveff]=1;
   
     if (mobilav!=0) {
       mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){
         fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
         printf(" Error in movingaverage mobilav=%d\n",mobilav);
       }
     }
   
     stepsize=(int) (stepm+YEARM-1)/YEARM;
     if (stepm<=12) stepsize=1;
     
     agelim=AGESUP;
     
     hstepm=1;
     hstepm=hstepm/stepm; 
     
     if (popforecast==1) {
       if((ficpop=fopen(popfile,"r"))==NULL) {
         printf("Problem with population file : %s\n",popfile);exit(0);
         fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0);
       } 
       popage=ivector(0,AGESUP);
       popeffectif=vector(0,AGESUP);
       popcount=vector(0,AGESUP);
       
       i=1;   
       while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1;
      
       imx=i;
       for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i];
     }
   
     for(cptcov=1,k=0;cptcov<=i2;cptcov++){
      for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){
         k=k+1;
         fprintf(ficrespop,"\n#******");
         for(j=1;j<=cptcoveff;j++) {
           fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
         }
         fprintf(ficrespop,"******\n");
         fprintf(ficrespop,"# Age");
         for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j);
         if (popforecast==1)  fprintf(ficrespop," [Population]");
         
         for (cpt=0; cpt<=0;cpt++) { 
           fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);   
           
           for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){ 
             nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); 
             nhstepm = nhstepm/hstepm; 
             
             p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             oldm=oldms;savm=savms;
             hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
           
             for (h=0; h<=nhstepm; h++){
               if (h==(int) (calagedatem+YEARM*cpt)) {
                 fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm);
               } 
               for(j=1; j<=nlstate+ndeath;j++) {
                 kk1=0.;kk2=0;
                 for(i=1; i<=nlstate;i++) {              
                   if (mobilav==1) 
                     kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod];
                   else {
                     kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod];
                   }
                 }
                 if (h==(int)(calagedatem+12*cpt)){
                   tabpop[(int)(agedeb)][j][cptcod]=kk1;
                     /*fprintf(ficrespop," %.3f", kk1);
                       if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*/
                 }
               }
               for(i=1; i<=nlstate;i++){
                 kk1=0.;
                   for(j=1; j<=nlstate;j++){
                     kk1= kk1+tabpop[(int)(agedeb)][j][cptcod]; 
                   }
                     tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)];
               }
   
               if (h==(int)(calagedatem+12*cpt)) for(j=1; j<=nlstate;j++) 
                 fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]);
             }
             free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           }
         }
    
     /******/
   
         for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) { 
           fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);   
           for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){ 
             nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); 
             nhstepm = nhstepm/hstepm; 
             
             p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             oldm=oldms;savm=savms;
             hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
             for (h=0; h<=nhstepm; h++){
               if (h==(int) (calagedatem+YEARM*cpt)) {
                 fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm);
               } 
               for(j=1; j<=nlstate+ndeath;j++) {
                 kk1=0.;kk2=0;
                 for(i=1; i<=nlstate;i++) {              
                   kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];    
                 }
                 if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);        
               }
             }
             free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           }
         }
      } 
     }
    
     if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
   
     if (popforecast==1) {
       free_ivector(popage,0,AGESUP);
       free_vector(popeffectif,0,AGESUP);
       free_vector(popcount,0,AGESUP);
     }
     free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     fclose(ficrespop);
   } /* End of popforecast */
   
   int fileappend(FILE *fichier, char *optionfich)
   {
     if((fichier=fopen(optionfich,"a"))==NULL) {
       printf("Problem with file: %s\n", optionfich);
       fprintf(ficlog,"Problem with file: %s\n", optionfich);
       return (0);
     }
     fflush(fichier);
     return (1);
   }
   
   
   /**************** function prwizard **********************/
   void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
   {
   
     /* Wizard to print covariance matrix template */
   
     char ca[32], cb[32], cc[32];
     int i,j, k, l, li, lj, lk, ll, jj, npar, itimes;
     int numlinepar;
   
     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
     fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
     for(i=1; i <=nlstate; i++){
       jj=0;
       for(j=1; j <=nlstate+ndeath; j++){
         if(j==i) continue;
         jj++;
         /*ca[0]= k+'a'-1;ca[1]='\0';*/
         printf("%1d%1d",i,j);
         fprintf(ficparo,"%1d%1d",i,j);
         for(k=1; k<=ncovmodel;k++){
           /*        printf(" %lf",param[i][j][k]); */
           /*        fprintf(ficparo," %lf",param[i][j][k]); */
           printf(" 0.");
           fprintf(ficparo," 0.");
         }
         printf("\n");
         fprintf(ficparo,"\n");
       }
     }
     printf("# Scales (for hessian or gradient estimation)\n");
     fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
     npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
     for(i=1; i <=nlstate; i++){
       jj=0;
       for(j=1; j <=nlstate+ndeath; j++){
         if(j==i) continue;
         jj++;
         fprintf(ficparo,"%1d%1d",i,j);
         printf("%1d%1d",i,j);
         fflush(stdout);
         for(k=1; k<=ncovmodel;k++){
           /*      printf(" %le",delti3[i][j][k]); */
           /*      fprintf(ficparo," %le",delti3[i][j][k]); */
           printf(" 0.");
           fprintf(ficparo," 0.");
         }
         numlinepar++;
         printf("\n");
         fprintf(ficparo,"\n");
       }
     }
     printf("# Covariance matrix\n");
   /* # 121 Var(a12)\n\ */
   /* # 122 Cov(b12,a12) Var(b12)\n\ */
   /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
   /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
   /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
   /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
   /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
   /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
     fflush(stdout);
     fprintf(ficparo,"# Covariance matrix\n");
     /* # 121 Var(a12)\n\ */
     /* # 122 Cov(b12,a12) Var(b12)\n\ */
     /* #   ...\n\ */
     /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
     
     for(itimes=1;itimes<=2;itimes++){
       jj=0;
       for(i=1; i <=nlstate; i++){
         for(j=1; j <=nlstate+ndeath; j++){
           if(j==i) continue;
           for(k=1; k<=ncovmodel;k++){
             jj++;
             ca[0]= k+'a'-1;ca[1]='\0';
             if(itimes==1){
               printf("#%1d%1d%d",i,j,k);
               fprintf(ficparo,"#%1d%1d%d",i,j,k);
             }else{
               printf("%1d%1d%d",i,j,k);
               fprintf(ficparo,"%1d%1d%d",i,j,k);
               /*  printf(" %.5le",matcov[i][j]); */
             }
             ll=0;
             for(li=1;li <=nlstate; li++){
               for(lj=1;lj <=nlstate+ndeath; lj++){
                 if(lj==li) continue;
                 for(lk=1;lk<=ncovmodel;lk++){
                   ll++;
                   if(ll<=jj){
                     cb[0]= lk +'a'-1;cb[1]='\0';
                     if(ll<jj){
                       if(itimes==1){
                         printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                         fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                       }else{
                         printf(" 0.");
                         fprintf(ficparo," 0.");
                       }
                     }else{
                       if(itimes==1){
                         printf(" Var(%s%1d%1d)",ca,i,j);
                         fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                       }else{
                         printf(" 0.");
                         fprintf(ficparo," 0.");
                       }
                     }
                   }
                 } /* end lk */
               } /* end lj */
             } /* end li */
             printf("\n");
             fprintf(ficparo,"\n");
             numlinepar++;
           } /* end k*/
         } /*end j */
       } /* end i */
     } /* end itimes */
   
   } /* end of prwizard */
   /******************* Gompertz Likelihood ******************************/
   double gompertz(double x[])
   { 
     double A,B,L=0.0,sump=0.,num=0.;
     int i,n=0; /* n is the size of the sample */
   
     for (i=0;i<=imx-1 ; i++) {
       sump=sump+weight[i];
       /*    sump=sump+1;*/
       num=num+1;
     }
    
    
     /* for (i=0; i<=imx; i++) 
        if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
   
     for (i=1;i<=imx ; i++)
       {
         if (cens[i] == 1 && wav[i]>1)
           A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
         
         if (cens[i] == 0 && wav[i]>1)
           A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
         
         /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
         if (wav[i] > 1 ) { /* ??? */
           L=L+A*weight[i];
           /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
         }
       }
   
    /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
    
     return -2*L*num/sump;
   }
   
   #ifdef GSL
   /******************* Gompertz_f Likelihood ******************************/
   double gompertz_f(const gsl_vector *v, void *params)
   { 
     double A,B,LL=0.0,sump=0.,num=0.;
     double *x= (double *) v->data;
     int i,n=0; /* n is the size of the sample */
   
     for (i=0;i<=imx-1 ; i++) {
       sump=sump+weight[i];
       /*    sump=sump+1;*/
       num=num+1;
     }
    
    
     /* for (i=0; i<=imx; i++) 
        if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
     printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
     for (i=1;i<=imx ; i++)
       {
         if (cens[i] == 1 && wav[i]>1)
           A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
         
         if (cens[i] == 0 && wav[i]>1)
           A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
         
         /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
         if (wav[i] > 1 ) { /* ??? */
           LL=LL+A*weight[i];
           /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
         }
       }
   
    /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
     printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
    
     return -2*LL*num/sump;
   }
   #endif
   
   /******************* Printing html file ***********/
   void printinghtmlmort(char fileres[], char title[], char datafile[], int firstpass, \
                     int lastpass, int stepm, int weightopt, char model[],\
                     int imx,  double p[],double **matcov,double agemortsup){
     int i,k;
   
     fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
     fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
     for (i=1;i<=2;i++) 
       fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
     fprintf(fichtm,"<br><br><img src=\"graphmort.png\">");
     fprintf(fichtm,"</ul>");
   
   fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
   
    fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
   
    for (k=agegomp;k<(agemortsup-2);k++) 
      fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
   
    
     fflush(fichtm);
   }
   
   /******************* Gnuplot file **************/
   void printinggnuplotmort(char fileres[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
   
     char dirfileres[132],optfileres[132];
     int m,cpt,k1,i,k,j,jk,k2,k3,ij,l;
     int ng;
   
   
     /*#ifdef windows */
     fprintf(ficgp,"cd \"%s\" \n",pathc);
       /*#endif */
   
   
     strcpy(dirfileres,optionfilefiname);
     strcpy(optfileres,"vpl");
     fprintf(ficgp,"set out \"graphmort.png\"\n "); 
     fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
     fprintf(ficgp, "set ter png small size 320, 240\n set log y\n"); 
     /* fprintf(ficgp, "set size 0.65,0.65\n"); */
     fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
   
   } 
   
   int readdata(char datafile[], int firstobs, int lastobs, int *imax)
   {
   
     /*-------- data file ----------*/
     FILE *fic;
     char dummy[]="                         ";
     int i, j, n;
     int linei, month, year,iout;
     char line[MAXLINE], linetmp[MAXLINE];
     char stra[80], strb[80];
     char *stratrunc;
     int lstra;
   
   
     if((fic=fopen(datafile,"r"))==NULL)    {
       printf("Problem while opening datafile: %s\n", datafile);return 1;
       fprintf(ficlog,"Problem while opening datafile: %s\n", datafile);return 1;
     }
   
     i=1;
     linei=0;
     while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
       linei=linei+1;
       for(j=strlen(line); j>=0;j--){  /* Untabifies line */
         if(line[j] == '\t')
           line[j] = ' ';
       }
       for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
         ;
       };
       line[j+1]=0;  /* Trims blanks at end of line */
       if(line[0]=='#'){
         fprintf(ficlog,"Comment line\n%s\n",line);
         printf("Comment line\n%s\n",line);
         continue;
       }
       trimbb(linetmp,line); /* Trims multiple blanks in line */
       for (j=0; line[j]!='\0';j++){
         line[j]=linetmp[j];
       }
     
   
       for (j=maxwav;j>=1;j--){
         cutv(stra, strb, line, ' '); 
         if(strb[0]=='.') { /* Missing status */
           lval=-1;
         }else{
           errno=0;
           lval=strtol(strb,&endptr,10); 
         /*        if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
           if( strb[0]=='\0' || (*endptr != '\0')){
             printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
             fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
             return 1;
           }
         }
         s[j][i]=lval;
         
         strcpy(line,stra);
         cutv(stra, strb,line,' ');
         if(iout=sscanf(strb,"%d/%d",&month, &year) != 0){
         }
         else  if(iout=sscanf(strb,"%s.",dummy) != 0){
           month=99;
           year=9999;
         }else{
           printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
           fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
           return 1;
         }
         anint[j][i]= (double) year; 
         mint[j][i]= (double)month; 
         strcpy(line,stra);
       } /* ENd Waves */
       
       cutv(stra, strb,line,' '); 
       if(iout=sscanf(strb,"%d/%d",&month, &year) != 0){
       }
       else  if(iout=sscanf(strb,"%s.",dummy) != 0){
         month=99;
         year=9999;
       }else{
         printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
           fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
           return 1;
       }
       andc[i]=(double) year; 
       moisdc[i]=(double) month; 
       strcpy(line,stra);
       
       cutv(stra, strb,line,' '); 
       if(iout=sscanf(strb,"%d/%d",&month, &year) != 0){
       }
       else  if(iout=sscanf(strb,"%s.", dummy) != 0){
         month=99;
         year=9999;
       }else{
         printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
         fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
           return 1;
       }
       if (year==9999) {
         printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
         fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
           return 1;
   
       }
       annais[i]=(double)(year);
       moisnais[i]=(double)(month); 
       strcpy(line,stra);
       
       cutv(stra, strb,line,' '); 
       errno=0;
       dval=strtod(strb,&endptr); 
       if( strb[0]=='\0' || (*endptr != '\0')){
         printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
         fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
         fflush(ficlog);
         return 1;
       }
       weight[i]=dval; 
       strcpy(line,stra);
       
       for (j=ncovcol;j>=1;j--){
         cutv(stra, strb,line,' '); 
         if(strb[0]=='.') { /* Missing status */
           lval=-1;
         }else{
           errno=0;
           lval=strtol(strb,&endptr,10); 
           if( strb[0]=='\0' || (*endptr != '\0')){
             printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
             fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
             return 1;
           }
         }
         if(lval <-1 || lval >1){
           printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
    Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
    for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
    For example, for multinomial values like 1, 2 and 3,\n \
    build V1=0 V2=0 for the reference value (1),\n \
           V1=1 V2=0 for (2) \n \
    and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
    output of IMaCh is often meaningless.\n \
    Exiting.\n",lval,linei, i,line,j);
           fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
    Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
    for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
    For example, for multinomial values like 1, 2 and 3,\n \
    build V1=0 V2=0 for the reference value (1),\n \
           V1=1 V2=0 for (2) \n \
    and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
    output of IMaCh is often meaningless.\n \
    Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
           return 1;
         }
         covar[j][i]=(double)(lval);
         strcpy(line,stra);
       }  
       lstra=strlen(stra);
        
       if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
         stratrunc = &(stra[lstra-9]);
         num[i]=atol(stratrunc);
       }
       else
         num[i]=atol(stra);
       /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
         printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
       
       i=i+1;
     } /* End loop reading  data */
   
     *imax=i-1; /* Number of individuals */
     fclose(fic);
    
     return (0);
     endread:
       printf("Exiting readdata: ");
       fclose(fic);
       return (1);
   
   
   
   }
   void removespace(char *str) {
     char *p1 = str, *p2 = str;
     do
       while (*p2 == ' ')
         p2++;
     while (*p1++ = *p2++);
   }
   
   int decodemodel ( char model[], int lastobs) /**< This routine decode the model and returns:
      * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age
      * - cptcovt total number of covariates of the model nbocc(+)+1 = 8
      * - cptcovn or number of covariates k of the models excluding age*products =6
      * - cptcovage number of covariates with age*products =2
      * - cptcovs number of simple covariates
      * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
      *     which is a new column after the 9 (ncovcol) variables. 
      * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
      * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
      *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
      * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
    */
   {
     int i, j, k, ks;
     int i1, j1, k1, k2;
     char modelsav[80];
     char stra[80], strb[80], strc[80], strd[80],stre[80];
   
     /*removespace(model);*/
     if (strlen(model) >1){ /* If there is at least 1 covariate */
       j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
       j=nbocc(model,'+'); /**< j=Number of '+' */
       j1=nbocc(model,'*'); /**< j1=Number of '*' */
       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V2*age+V3 +V3*V4=> V1 + V3 =2  */
       cptcovt= j+1; /* Number of total covariates in the model V1 + V2*age+ V3 + V3*V4=> 4*/
                     /* including age products which are counted in cptcovage.
                     /* but the covariates which are products must be treated separately: ncovn=4- 2=2 (V1+V3). */
       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
       strcpy(modelsav,model); 
       if (strstr(model,"AGE") !=0){
         printf("Error. AGE must be in lower case 'age' model=%s ",model);
         fprintf(ficlog,"Error. AGE must be in lower case model=%s ",model);fflush(ficlog);
         return 1;
       }
       if (strstr(model,"v") !=0){
         printf("Error. 'v' must be in upper case 'V' model=%s ",model);
         fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
         return 1;
       }
       
       /*   Design
        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
        *  <          ncovcol=8                >
        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
        *   k=  1    2      3       4     5       6      7        8
        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
        *  covar[k,i], value of kth covariate if not including age for individual i:
        *       covar[1][i]= (V2), covar[4][i]=(V3), covar[8][i]=(V8)
        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[4]=3 Tvar[8]=8
        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
        *  Tage[++cptcovage]=k
        *       if products, new covar are created after ncovcol with k1
        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
        *  <          ncovcol=8                >
        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
        * p Tprod[1]@2={                         6, 5}
        *p Tvard[1][1]@4= {7, 8, 5, 6}
        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
        *How to reorganize?
        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
        *       {2,   1,     4,      8,    5,      6,     3,       7}
        * Struct []
        */
   
       /* This loop fills the array Tvar from the string 'model'.*/
       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
       /*  k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
       /*  k=3 V4 Tvar[k=3]= 4 (from V4) */
       /*  k=2 V1 Tvar[k=2]= 1 (from V1) */
       /*  k=1 Tvar[1]=2 (from V2) */
       /*  k=5 Tvar[5] */
       /* for (k=1; k<=cptcovn;k++) { */
       /*  cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]]; */
       /*  } */
       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
       /*
        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
       for(k=cptcovt; k>=1;k--) /**< Number of covariates */
           Tvar[k]=0;
       cptcovage=0;
       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
         cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
                                        modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
         if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
         /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
         /*scanf("%d",i);*/
         if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
           cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
           if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
             /* covar is not filled and then is empty */
             cptcovprod--;
             cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
             Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2 */
             cptcovage++; /* Sums the number of covariates which include age as a product */
             Tage[cptcovage]=k;  /* Tage[1] = 4 */
             /*printf("stre=%s ", stre);*/
           } else if (strcmp(strd,"age")==0) { /* or age*Vn */
             cptcovprod--;
             cutl(stre,strb,strc,'V');
             Tvar[k]=atoi(stre);
             cptcovage++;
             Tage[cptcovage]=k;
           } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
             /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
             cptcovn++;
             cptcovprodnoage++;k1++;
             cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
             Tvar[k]=ncovcol+k1; /* For model-covariate k tells which data-covariate to use but
                                     because this model-covariate is a construction we invent a new column
                                     ncovcol + k1
                                     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                                     Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
             cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
             Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
             Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
             Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
             k2=k2+2;
             Tvar[cptcovt+k2]=Tvard[k1][1]; /* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) */
             Tvar[cptcovt+k2+1]=Tvard[k1][2];  /* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) */
             for (i=1; i<=lastobs;i++){
               /* Computes the new covariate which is a product of
                  covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
               covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
             }
           } /* End age is not in the model */
         } /* End if model includes a product */
         else { /* no more sum */
           /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
          /*  scanf("%d",i);*/
           cutl(strd,strc,strb,'V');
           ks++; /**< Number of simple covariates */
           cptcovn++;
           Tvar[k]=atoi(strd);
         }
         strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
         /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
           scanf("%d",i);*/
       } /* end of loop + */
     } /* end model */
     
     /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
       If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
   
     /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
     printf("cptcovprod=%d ", cptcovprod);
     fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
   
     scanf("%d ",i);*/
   
   
     return (0); /* with covar[new additional covariate if product] and Tage if age */ 
     endread:
       printf("Exiting decodemodel: ");
       return (1);
   }
   
   calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
   {
     int i, m;
   
     for (i=1; i<=imx; i++) {
       for(m=2; (m<= maxwav); m++) {
         if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
           anint[m][i]=9999;
           s[m][i]=-1;
         }
         if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
           *nberr++;
           printf("Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results are biased\n",(int)moisdc[i],(int)andc[i],num[i],i);
           fprintf(ficlog,"Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results are biased\n",(int)moisdc[i],(int)andc[i],num[i],i);
           s[m][i]=-1;
         }
         if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
           *nberr++;
           printf("Error! Month of death of individual %ld on line %d was unknown %2d, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,(int)moisdc[i]); 
           fprintf(ficlog,"Error! Month of death of individual %ld on line %d was unknown %f, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,moisdc[i]); 
           s[m][i]=-1; /* We prefer to skip it (and to skip it in version 0.8a1 too */
         }
       }
     }
   
     for (i=1; i<=imx; i++)  {
       agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
       for(m=firstpass; (m<= lastpass); m++){
         if(s[m][i] >0 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){
           if (s[m][i] >= nlstate+1) {
             if(agedc[i]>0)
               if((int)moisdc[i]!=99 && (int)andc[i]!=9999)
                 agev[m][i]=agedc[i];
             /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
               else {
                 if ((int)andc[i]!=9999){
                   nbwarn++;
                   printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   agev[m][i]=-1;
                 }
               }
           }
           else if(s[m][i] !=9){ /* Standard case, age in fractional
                                    years but with the precision of a month */
             agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
             if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
               agev[m][i]=1;
             else if(agev[m][i] < *agemin){ 
               *agemin=agev[m][i];
               printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
             }
             else if(agev[m][i] >*agemax){
               *agemax=agev[m][i];
               printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);
             }
             /*agev[m][i]=anint[m][i]-annais[i];*/
             /*     agev[m][i] = age[i]+2*m;*/
           }
           else { /* =9 */
             agev[m][i]=1;
             s[m][i]=-1;
           }
         }
         else /*= 0 Unknown */
           agev[m][i]=1;
       }
       
     }
     for (i=1; i<=imx; i++)  {
       for(m=firstpass; (m<=lastpass); m++){
         if (s[m][i] > (nlstate+ndeath)) {
           *nberr++;
           printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
           fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
           return 1;
         }
       }
     }
   
     /*for (i=1; i<=imx; i++){
     for (m=firstpass; (m<lastpass); m++){
        printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
   }
   
   }*/
   
   
     printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
     fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
   
     return (0);
     endread:
       printf("Exiting calandcheckages: ");
       return (1);
   }
   
   
   /***********************************************/
   /**************** Main Program *****************/
   /***********************************************/
   
   int main(int argc, char *argv[])
   {
   #ifdef GSL
     const gsl_multimin_fminimizer_type *T;
     size_t iteri = 0, it;
     int rval = GSL_CONTINUE;
     int status = GSL_SUCCESS;
     double ssval;
   #endif
     int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
     int i,j, k, n=MAXN,iter,m,size=100,cptcode, cptcod;
     int linei, month, year,iout;
     int jj, ll, li, lj, lk, imk;
     int numlinepar=0; /* Current linenumber of parameter file */
     int itimes;
     int NDIM=2;
     int vpopbased=0;
   
     char ca[32], cb[32], cc[32];
     /*  FILE *fichtm; *//* Html File */
     /* FILE *ficgp;*/ /*Gnuplot File */
     struct stat info;
     double agedeb, agefin,hf;
     double ageminpar=1.e20,agemin=1.e20, agemaxpar=-1.e20, agemax=-1.e20;
   
     double fret;
     double **xi,tmp,delta;
   
     double dum; /* Dummy variable */
     double ***p3mat;
     double ***mobaverage;
     int *indx;
     char line[MAXLINE], linepar[MAXLINE];
     char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE],model[MAXLINE];
     char pathr[MAXLINE], pathimach[MAXLINE]; 
     char **bp, *tok, *val; /* pathtot */
     int firstobs=1, lastobs=10;
     int sdeb, sfin; /* Status at beginning and end */
     int c,  h , cpt,l;
     int ju,jl, mi;
     int i1,j1, jk,aa,bb, stepsize, ij;
     int jnais,jdc,jint4,jint1,jint2,jint3,*tab; 
     int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
     int mobilav=0,popforecast=0;
     int hstepm, nhstepm;
     int agemortsup;
     float  sumlpop=0.;
     double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
     double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
   
     double bage, fage, age, agelim, agebase;
     double ftolpl=FTOL;
     double **prlim;
     double ***param; /* Matrix of parameters */
     double  *p;
     double **matcov; /* Matrix of covariance */
     double ***delti3; /* Scale */
     double *delti; /* Scale */
     double ***eij, ***vareij;
     double **varpl; /* Variances of prevalence limits by age */
     double *epj, vepp;
     double kk1, kk2;
     double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
     double **ximort;
     char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
     int *dcwave;
   
     char z[1]="c", occ;
   
     /*char  *strt;*/
     char strtend[80];
   
     long total_usecs;
    
   /*   setlocale (LC_ALL, ""); */
   /*   bindtextdomain (PACKAGE, LOCALEDIR); */
   /*   textdomain (PACKAGE); */
   /*   setlocale (LC_CTYPE, ""); */
   /*   setlocale (LC_MESSAGES, ""); */
   
     /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
     (void) gettimeofday(&start_time,&tzp);
     curr_time=start_time;
     tm = *localtime(&start_time.tv_sec);
     tmg = *gmtime(&start_time.tv_sec);
     strcpy(strstart,asctime(&tm));
   
   /*  printf("Localtime (at start)=%s",strstart); */
   /*  tp.tv_sec = tp.tv_sec +86400; */
   /*  tm = *localtime(&start_time.tv_sec); */
   /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
   /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
   /*   tmg.tm_hour=tmg.tm_hour + 1; */
   /*   tp.tv_sec = mktime(&tmg); */
   /*   strt=asctime(&tmg); */
   /*   printf("Time(after) =%s",strstart);  */
   /*  (void) time (&time_value);
   *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
   *  tm = *localtime(&time_value);
   *  strstart=asctime(&tm);
   *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
   */
   
     nberr=0; /* Number of errors and warnings */
     nbwarn=0;
     getcwd(pathcd, size);
   
     printf("\n%s\n%s",version,fullversion);
     if(argc <=1){
       printf("\nEnter the parameter file name: ");
       fgets(pathr,FILENAMELENGTH,stdin);
       i=strlen(pathr);
       if(pathr[i-1]=='\n')
         pathr[i-1]='\0';
      for (tok = pathr; tok != NULL; ){
         printf("Pathr |%s|\n",pathr);
         while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
         printf("val= |%s| pathr=%s\n",val,pathr);
         strcpy (pathtot, val);
         if(pathr[0] == '\0') break; /* Dirty */
       }
     }
     else{
       strcpy(pathtot,argv[1]);
     }
     /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
     /*cygwin_split_path(pathtot,path,optionfile);
       printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
     /* cutv(path,optionfile,pathtot,'\\');*/
   
     /* Split argv[0], imach program to get pathimach */
     printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
     split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
     printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
    /*   strcpy(pathimach,argv[0]); */
     /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
     split(pathtot,path,optionfile,optionfilext,optionfilefiname);
     printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
     chdir(path); /* Can be a relative path */
     if(getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
       printf("Current directory %s!\n",pathcd);
     strcpy(command,"mkdir ");
     strcat(command,optionfilefiname);
     if((outcmd=system(command)) != 0){
       printf("Problem creating directory or it already exists %s%s, err=%d\n",path,optionfilefiname,outcmd);
       /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
       /* fclose(ficlog); */
   /*     exit(1); */
     }
   /*   if((imk=mkdir(optionfilefiname))<0){ */
   /*     perror("mkdir"); */
   /*   } */
   
     /*-------- arguments in the command line --------*/
   
     /* Log file */
     strcat(filelog, optionfilefiname);
     strcat(filelog,".log");    /* */
     if((ficlog=fopen(filelog,"w"))==NULL)    {
       printf("Problem with logfile %s\n",filelog);
       goto end;
     }
     fprintf(ficlog,"Log filename:%s\n",filelog);
     fprintf(ficlog,"\n%s\n%s",version,fullversion);
     fprintf(ficlog,"\nEnter the parameter file name: \n");
     fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
    path=%s \n\
    optionfile=%s\n\
    optionfilext=%s\n\
    optionfilefiname=%s\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
   
     printf("Local time (at start):%s",strstart);
     fprintf(ficlog,"Local time (at start): %s",strstart);
     fflush(ficlog);
   /*   (void) gettimeofday(&curr_time,&tzp); */
   /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tv_sec-start_time.tv_sec,tmpout)); */
   
     /* */
     strcpy(fileres,"r");
     strcat(fileres, optionfilefiname);
     strcat(fileres,".txt");    /* Other files have txt extension */
   
     /*---------arguments file --------*/
   
     if((ficpar=fopen(optionfile,"r"))==NULL)    {
       printf("Problem with optionfile %s with errno=%s\n",optionfile,strerror(errno));
       fprintf(ficlog,"Problem with optionfile %s with errno=%s\n",optionfile,strerror(errno));
       fflush(ficlog);
       /* goto end; */
       exit(70); 
     }
   
   
   
     strcpy(filereso,"o");
     strcat(filereso,fileres);
     if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
       printf("Problem with Output resultfile: %s\n", filereso);
       fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
       fflush(ficlog);
       goto end;
     }
   
     /* Reads comments: lines beginning with '#' */
     numlinepar=0;
     while((c=getc(ficpar))=='#' && c!= EOF){
       ungetc(c,ficpar);
       fgets(line, MAXLINE, ficpar);
       numlinepar++;
       fputs(line,stdout);
       fputs(line,ficparo);
       fputs(line,ficlog);
     }
     ungetc(c,ficpar);
   
     fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model);
     numlinepar++;
     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model);
     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model);
     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model);
     fflush(ficlog);
     while((c=getc(ficpar))=='#' && c!= EOF){
       ungetc(c,ficpar);
       fgets(line, MAXLINE, ficpar);
       numlinepar++;
       fputs(line, stdout);
       //puts(line);
       fputs(line,ficparo);
       fputs(line,ficlog);
     }
     ungetc(c,ficpar);
   
      
     covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
     cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
     /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
        v1+v2*age+v2*v3 makes cptcovn = 3
     */
     if (strlen(model)>1) 
       ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7*/
     else
       ncovmodel=2;
     nvar=ncovmodel-1; /* Suppressing age as a basic covariate */
     nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
     npar= nforce*ncovmodel; /* Number of parameters like aij*/
     if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
       printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
       fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
       fflush(stdout);
       fclose (ficlog);
       goto end;
     }
     delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
     delti=delti3[1][1];
     /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
     if(mle==-1){ /* Print a wizard for help writing covariance matrix */
       prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
       printf(" You choose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
       fprintf(ficlog," You choose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
       free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
       fclose (ficparo);
       fclose (ficlog);
       goto end;
       exit(0);
     }
     else if(mle==-3) {
       prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
       printf(" You choose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
       fprintf(ficlog," You choose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
       param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
       matcov=matrix(1,npar,1,npar);
     }
     else{
       /* Read guessed parameters */
       /* Reads comments: lines beginning with '#' */
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         numlinepar++;
         fputs(line,stdout);
         fputs(line,ficparo);
         fputs(line,ficlog);
       }
       ungetc(c,ficpar);
       
       param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
       for(i=1; i <=nlstate; i++){
         j=0;
         for(jj=1; jj <=nlstate+ndeath; jj++){
           if(jj==i) continue;
           j++;
           fscanf(ficpar,"%1d%1d",&i1,&j1);
           if ((i1 != i) && (j1 != j)){
             printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
   It might be a problem of design; if ncovcol and the model are correct\n \
   run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
             exit(1);
           }
           fprintf(ficparo,"%1d%1d",i1,j1);
           if(mle==1)
             printf("%1d%1d",i,j);
           fprintf(ficlog,"%1d%1d",i,j);
           for(k=1; k<=ncovmodel;k++){
             fscanf(ficpar," %lf",&param[i][j][k]);
             if(mle==1){
               printf(" %lf",param[i][j][k]);
               fprintf(ficlog," %lf",param[i][j][k]);
             }
             else
               fprintf(ficlog," %lf",param[i][j][k]);
             fprintf(ficparo," %lf",param[i][j][k]);
           }
           fscanf(ficpar,"\n");
           numlinepar++;
           if(mle==1)
             printf("\n");
           fprintf(ficlog,"\n");
           fprintf(ficparo,"\n");
         }
       }  
       fflush(ficlog);
   
       /* Reads scales values */
       p=param[1][1];
       
       /* Reads comments: lines beginning with '#' */
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         numlinepar++;
         fputs(line,stdout);
         fputs(line,ficparo);
         fputs(line,ficlog);
       }
       ungetc(c,ficpar);
   
       for(i=1; i <=nlstate; i++){
         for(j=1; j <=nlstate+ndeath-1; j++){
           fscanf(ficpar,"%1d%1d",&i1,&j1);
           if ((i1-i)*(j1-j)!=0){
             printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
             exit(1);
           }
           printf("%1d%1d",i,j);
           fprintf(ficparo,"%1d%1d",i1,j1);
           fprintf(ficlog,"%1d%1d",i1,j1);
           for(k=1; k<=ncovmodel;k++){
             fscanf(ficpar,"%le",&delti3[i][j][k]);
             printf(" %le",delti3[i][j][k]);
             fprintf(ficparo," %le",delti3[i][j][k]);
             fprintf(ficlog," %le",delti3[i][j][k]);
           }
           fscanf(ficpar,"\n");
           numlinepar++;
           printf("\n");
           fprintf(ficparo,"\n");
           fprintf(ficlog,"\n");
         }
       }
       fflush(ficlog);
   
       /* Reads covariance matrix */
       delti=delti3[1][1];
   
   
       /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
     
       /* Reads comments: lines beginning with '#' */
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         numlinepar++;
         fputs(line,stdout);
         fputs(line,ficparo);
         fputs(line,ficlog);
       }
       ungetc(c,ficpar);
     
       matcov=matrix(1,npar,1,npar);
       for(i=1; i <=npar; i++)
         for(j=1; j <=npar; j++) matcov[i][j]=0.;
         
       for(i=1; i <=npar; i++){
         fscanf(ficpar,"%s",str);
         if(mle==1)
           printf("%s",str);
         fprintf(ficlog,"%s",str);
         fprintf(ficparo,"%s",str);
         for(j=1; j <=i; j++){
           fscanf(ficpar," %le",&matcov[i][j]);
           if(mle==1){
             printf(" %.5le",matcov[i][j]);
           }
           fprintf(ficlog," %.5le",matcov[i][j]);
           fprintf(ficparo," %.5le",matcov[i][j]);
         }
         fscanf(ficpar,"\n");
         numlinepar++;
         if(mle==1)
           printf("\n");
         fprintf(ficlog,"\n");
         fprintf(ficparo,"\n");
       }
       for(i=1; i <=npar; i++)
         for(j=i+1;j<=npar;j++)
           matcov[i][j]=matcov[j][i];
       
       if(mle==1)
         printf("\n");
       fprintf(ficlog,"\n");
       
       fflush(ficlog);
       
       /*-------- Rewriting parameter file ----------*/
       strcpy(rfileres,"r");    /* "Rparameterfile */
       strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
       strcat(rfileres,".");    /* */
       strcat(rfileres,optionfilext);    /* Other files have txt extension */
       if((ficres =fopen(rfileres,"w"))==NULL) {
         printf("Problem writing new parameter file: %s\n", fileres);goto end;
         fprintf(ficlog,"Problem writing new parameter file: %s\n", fileres);goto end;
       }
       fprintf(ficres,"#%s\n",version);
     }    /* End of mle != -3 */
   
   
     n= lastobs;
     num=lvector(1,n);
     moisnais=vector(1,n);
     annais=vector(1,n);
     moisdc=vector(1,n);
     andc=vector(1,n);
     agedc=vector(1,n);
     cod=ivector(1,n);
     weight=vector(1,n);
     for(i=1;i<=n;i++) weight[i]=1.0; /* Equal weights, 1 by default */
     mint=matrix(1,maxwav,1,n);
     anint=matrix(1,maxwav,1,n);
     s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
     tab=ivector(1,NCOVMAX);
     ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
   
     /* Reads data from file datafile */
     if (readdata(datafile, firstobs, lastobs, &imx)==1)
       goto end;
   
     /* Calculation of the number of parameters from char model */
       /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
           k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
           k=3 V4 Tvar[k=3]= 4 (from V4)
           k=2 V1 Tvar[k=2]= 1 (from V1)
           k=1 Tvar[1]=2 (from V2)
       */
     Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
     /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
         For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
         Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
     */
     /* For model-covariate k tells which data-covariate to use but
       because this model-covariate is a construction we invent a new column
       ncovcol + k1
       If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
       Tvar[3=V1*V4]=4+1 etc */
     Tprod=ivector(1,NCOVMAX); /* Gives the position of a product */
     /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
        if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
     */
     Tvaraff=ivector(1,NCOVMAX); /* Unclear */
     Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
                               * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                               * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
     Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
                            4 covariates (3 plus signs)
                            Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                         */  
   
     if(decodemodel(model, lastobs) == 1)
       goto end;
   
     if((double)(lastobs-imx)/(double)imx > 1.10){
       nbwarn++;
       printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
       fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
     }
       /*  if(mle==1){*/
     if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
       for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
     }
   
       /*-calculation of age at interview from date of interview and age at death -*/
     agev=matrix(1,maxwav,1,imx);
   
     if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
       goto end;
   
   
     agegomp=(int)agemin;
     free_vector(moisnais,1,n);
     free_vector(annais,1,n);
     /* free_matrix(mint,1,maxwav,1,n);
        free_matrix(anint,1,maxwav,1,n);*/
     free_vector(moisdc,1,n);
     free_vector(andc,1,n);
     /* */
     
     wav=ivector(1,imx);
     dh=imatrix(1,lastpass-firstpass+1,1,imx);
     bh=imatrix(1,lastpass-firstpass+1,1,imx);
     mw=imatrix(1,lastpass-firstpass+1,1,imx);
      
     /* Concatenates waves */
     concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
     /* */
    
     /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
   
     nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
     ncodemax[1]=1;
     Ndum =ivector(-1,NCOVMAX);  
     if (ncovmodel > 2)
       tricode(Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
   
     codtab=imatrix(1,100,1,10); /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
     /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtab[100][10]);*/
     h=0;
   
   
     /*if (cptcovn > 0) */
         
    
     m=pow(2,cptcoveff);
    
     for(k=1;k<=cptcoveff; k++){ /* scans any effective covariate */
       for(i=1; i <=pow(2,cptcoveff-k);i++){ /* i=1 to 8/1=8; i=1 to 8/2=4; i=1 to 8/8=1 */ 
         for(j=1; j <= ncodemax[k]; j++){ /* For each modality of this covariate ncodemax=2*/
           for(cpt=1; cpt <=pow(2,k-1); cpt++){  /* cpt=1 to 8/2**(3+1-1 or 3+1-3) =1 or 4 */ 
             h++;
             if (h>m) 
               h=1;
             /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
              *     h     1     2     3     4
              *______________________________  
              *     1 i=1 1 i=1 1 i=1 1 i=1 1
              *     2     2     1     1     1
              *     3 i=2 1     2     1     1
              *     4     2     2     1     1
              *     5 i=3 1 i=2 1     2     1
              *     6     2     1     2     1
              *     7 i=4 1     2     2     1
              *     8     2     2     2     1
              *     9 i=5 1 i=3 1 i=2 1     1
              *    10     2     1     1     1
              *    11 i=6 1     2     1     1
              *    12     2     2     1     1
              *    13 i=7 1 i=4 1     2     1    
              *    14     2     1     2     1
              *    15 i=8 1     2     2     1
              *    16     2     2     2     1
              */
             codtab[h][k]=j;
             /*codtab[h][Tvar[k]]=j;*/
             printf("h=%d k=%d j=%d codtab[h][k]=%d Tvar[k]=%d codtab[h][Tvar[k]]=%d \n",h, k,j,codtab[h][k],Tvar[k],codtab[h][Tvar[k]]);
           } 
         }
       }
     } 
     /* printf("codtab[1][2]=%d codtab[2][2]=%d",codtab[1][2],codtab[2][2]); 
        codtab[1][2]=1;codtab[2][2]=2; */
     /* for(i=1; i <=m ;i++){ 
        for(k=1; k <=cptcovn; k++){
          printf("i=%d k=%d %d %d ",i,k,codtab[i][k], cptcoveff);
        }
        printf("\n");
        }
        scanf("%d",i);*/
   
    free_ivector(Ndum,-1,NCOVMAX);
   
   
       
     /*------------ gnuplot -------------*/
     strcpy(optionfilegnuplot,optionfilefiname);
     if(mle==-3)
       strcat(optionfilegnuplot,"-mort");
     strcat(optionfilegnuplot,".gp");
   
     if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
       printf("Problem with file %s",optionfilegnuplot);
     }
     else{
       fprintf(ficgp,"\n# %s\n", version); 
       fprintf(ficgp,"# %s\n", optionfilegnuplot); 
       //fprintf(ficgp,"set missing 'NaNq'\n");
       fprintf(ficgp,"set datafile missing 'NaNq'\n");
     }
     /*  fclose(ficgp);*/
     /*--------- index.htm --------*/
   
     strcpy(optionfilehtm,optionfilefiname); /* Main html file */
     if(mle==-3)
       strcat(optionfilehtm,"-mort");
     strcat(optionfilehtm,".htm");
     if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
       printf("Problem with %s \n",optionfilehtm);
       exit(0);
     }
   
     strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
     strcat(optionfilehtmcov,"-cov.htm");
     if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
       printf("Problem with %s \n",optionfilehtmcov), exit(0);
     }
     else{
     fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
   <hr size=\"2\" color=\"#EC5E5E\"> \n\
   Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=%s<br>\n",\
             optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
     }
   
     fprintf(fichtm,"<html><head>\n<title>IMaCh %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
   <hr size=\"2\" color=\"#EC5E5E\"> \n\
   Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=%s<br>\n\
   \n\
   <hr  size=\"2\" color=\"#EC5E5E\">\
    <ul><li><h4>Parameter files</h4>\n\
    - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
    - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
    - Log file of the run: <a href=\"%s\">%s</a><br>\n\
    - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
    - Date and time at start: %s</ul>\n",\
             optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
             optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
             fileres,fileres,\
             filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
     fflush(fichtm);
   
     strcpy(pathr,path);
     strcat(pathr,optionfilefiname);
     chdir(optionfilefiname); /* Move to directory named optionfile */
     
     /* Calculates basic frequencies. Computes observed prevalence at single age
        and prints on file fileres'p'. */
     freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart);
   
     fprintf(fichtm,"\n");
     fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
   Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
   Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
             imx,agemin,agemax,jmin,jmax,jmean);
     pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
       
      
     /* For Powell, parameters are in a vector p[] starting at p[1]
        so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
     p=param[1][1]; /* *(*(*(param +1)+1)+0) */
   
     globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
   
     if (mle==-3){
       ximort=matrix(1,NDIM,1,NDIM); 
   /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
       cens=ivector(1,n);
       ageexmed=vector(1,n);
       agecens=vector(1,n);
       dcwave=ivector(1,n);
    
       for (i=1; i<=imx; i++){
         dcwave[i]=-1;
         for (m=firstpass; m<=lastpass; m++)
           if (s[m][i]>nlstate) {
             dcwave[i]=m;
             /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
             break;
           }
       }
   
       for (i=1; i<=imx; i++) {
         if (wav[i]>0){
           ageexmed[i]=agev[mw[1][i]][i];
           j=wav[i];
           agecens[i]=1.; 
   
           if (ageexmed[i]> 1 && wav[i] > 0){
             agecens[i]=agev[mw[j][i]][i];
             cens[i]= 1;
           }else if (ageexmed[i]< 1) 
             cens[i]= -1;
           if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
             cens[i]=0 ;
         }
         else cens[i]=-1;
       }
       
       for (i=1;i<=NDIM;i++) {
         for (j=1;j<=NDIM;j++)
           ximort[i][j]=(i == j ? 1.0 : 0.0);
       }
       
       /*p[1]=0.0268; p[NDIM]=0.083;*/
       /*printf("%lf %lf", p[1], p[2]);*/
       
       
   #ifdef GSL
       printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
   #elsedef
       printf("Powell\n");  fprintf(ficlog,"Powell\n");
   #endif
       strcpy(filerespow,"pow-mort"); 
       strcat(filerespow,fileres);
       if((ficrespow=fopen(filerespow,"w"))==NULL) {
         printf("Problem with resultfile: %s\n", filerespow);
         fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
       }
   #ifdef GSL
       fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
   #elsedef
       fprintf(ficrespow,"# Powell\n# iter -2*LL");
   #endif
       /*  for (i=1;i<=nlstate;i++)
           for(j=1;j<=nlstate+ndeath;j++)
           if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
       */
       fprintf(ficrespow,"\n");
   #ifdef GSL
       /* gsl starts here */ 
       T = gsl_multimin_fminimizer_nmsimplex;
       gsl_multimin_fminimizer *sfm = NULL;
       gsl_vector *ss, *x;
       gsl_multimin_function minex_func;
   
       /* Initial vertex size vector */
       ss = gsl_vector_alloc (NDIM);
       
       if (ss == NULL){
         GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
       }
       /* Set all step sizes to 1 */
       gsl_vector_set_all (ss, 0.001);
   
       /* Starting point */
       
       x = gsl_vector_alloc (NDIM);
       
       if (x == NULL){
         gsl_vector_free(ss);
         GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
       }
     
       /* Initialize method and iterate */
       /*     p[1]=0.0268; p[NDIM]=0.083; */
   /*     gsl_vector_set(x, 0, 0.0268); */
   /*     gsl_vector_set(x, 1, 0.083); */
       gsl_vector_set(x, 0, p[1]);
       gsl_vector_set(x, 1, p[2]);
   
       minex_func.f = &gompertz_f;
       minex_func.n = NDIM;
       minex_func.params = (void *)&p; /* ??? */
       
       sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
       gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
       
       printf("Iterations beginning .....\n\n");
       printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
   
       iteri=0;
       while (rval == GSL_CONTINUE){
         iteri++;
         status = gsl_multimin_fminimizer_iterate(sfm);
         
         if (status) printf("error: %s\n", gsl_strerror (status));
         fflush(0);
         
         if (status) 
           break;
         
         rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
         ssval = gsl_multimin_fminimizer_size (sfm);
         
         if (rval == GSL_SUCCESS)
           printf ("converged to a local maximum at\n");
         
         printf("%5d ", iteri);
         for (it = 0; it < NDIM; it++){
           printf ("%10.5f ", gsl_vector_get (sfm->x, it));
         }
         printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
       }
       
       printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
       
       gsl_vector_free(x); /* initial values */
       gsl_vector_free(ss); /* inital step size */
       for (it=0; it<NDIM; it++){
         p[it+1]=gsl_vector_get(sfm->x,it);
         fprintf(ficrespow," %.12lf", p[it]);
       }
       gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
   #endif
   #ifdef POWELL
        powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
   #endif  
       fclose(ficrespow);
       
       hesscov(matcov, p, NDIM, delti, 1e-4, gompertz); 
   
       for(i=1; i <=NDIM; i++)
         for(j=i+1;j<=NDIM;j++)
           matcov[i][j]=matcov[j][i];
       
       printf("\nCovariance matrix\n ");
       for(i=1; i <=NDIM; i++) {
         for(j=1;j<=NDIM;j++){ 
           printf("%f ",matcov[i][j]);
         }
         printf("\n ");
       }
       
       printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
       for (i=1;i<=NDIM;i++) 
         printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
   
       lsurv=vector(1,AGESUP);
       lpop=vector(1,AGESUP);
       tpop=vector(1,AGESUP);
       lsurv[agegomp]=100000;
       
       for (k=agegomp;k<=AGESUP;k++) {
         agemortsup=k;
         if (p[1]*exp(p[2]*(k-agegomp))>1) break;
       }
       
       for (k=agegomp;k<agemortsup;k++)
         lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
       
       for (k=agegomp;k<agemortsup;k++){
         lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
         sumlpop=sumlpop+lpop[k];
       }
       
       tpop[agegomp]=sumlpop;
       for (k=agegomp;k<(agemortsup-3);k++){
         /*  tpop[k+1]=2;*/
         tpop[k+1]=tpop[k]-lpop[k];
       }
       
       
       printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
       for (k=agegomp;k<(agemortsup-2);k++) 
         printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
       
       
       replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
       printinggnuplotmort(fileres, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
       
       printinghtmlmort(fileres,title,datafile, firstpass, lastpass, \
                        stepm, weightopt,\
                        model,imx,p,matcov,agemortsup);
       
       free_vector(lsurv,1,AGESUP);
       free_vector(lpop,1,AGESUP);
       free_vector(tpop,1,AGESUP);
   #ifdef GSL
       free_ivector(cens,1,n);
       free_vector(agecens,1,n);
       free_ivector(dcwave,1,n);
       free_matrix(ximort,1,NDIM,1,NDIM);
   #endif
     } /* Endof if mle==-3 */
     
     else{ /* For mle >=1 */
       globpr=0;/* debug */
       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
       printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
       for (k=1; k<=npar;k++)
         printf(" %d %8.5f",k,p[k]);
       printf("\n");
       globpr=1; /* to print the contributions */
       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
       printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
       for (k=1; k<=npar;k++)
         printf(" %d %8.5f",k,p[k]);
       printf("\n");
       if(mle>=1){ /* Could be 1 or 2 */
         mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
       }
       
       /*--------- results files --------------*/
       fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate, ndeath, maxwav, weightopt,model);
       
       
       fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
       printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
       fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
       for(i=1,jk=1; i <=nlstate; i++){
         for(k=1; k <=(nlstate+ndeath); k++){
           if (k != i) {
             printf("%d%d ",i,k);
             fprintf(ficlog,"%d%d ",i,k);
             fprintf(ficres,"%1d%1d ",i,k);
             for(j=1; j <=ncovmodel; j++){
               printf("%lf ",p[jk]);
               fprintf(ficlog,"%lf ",p[jk]);
               fprintf(ficres,"%lf ",p[jk]);
               jk++; 
             }
             printf("\n");
             fprintf(ficlog,"\n");
             fprintf(ficres,"\n");
           }
         }
       }
       if(mle!=0){
         /* Computing hessian and covariance matrix */
         ftolhess=ftol; /* Usually correct */
         hesscov(matcov, p, npar, delti, ftolhess, func);
       }
       fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
       printf("# Scales (for hessian or gradient estimation)\n");
       fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
       for(i=1,jk=1; i <=nlstate; i++){
         for(j=1; j <=nlstate+ndeath; j++){
           if (j!=i) {
             fprintf(ficres,"%1d%1d",i,j);
             printf("%1d%1d",i,j);
             fprintf(ficlog,"%1d%1d",i,j);
             for(k=1; k<=ncovmodel;k++){
               printf(" %.5e",delti[jk]);
               fprintf(ficlog," %.5e",delti[jk]);
               fprintf(ficres," %.5e",delti[jk]);
               jk++;
             }
             printf("\n");
             fprintf(ficlog,"\n");
             fprintf(ficres,"\n");
           }
         }
       }
       
       fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
       if(mle>=1)
         printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
       fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
       /* # 121 Var(a12)\n\ */
       /* # 122 Cov(b12,a12) Var(b12)\n\ */
       /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
       /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
       /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
       /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
       /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
       /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
       
       
       /* Just to have a covariance matrix which will be more understandable
          even is we still don't want to manage dictionary of variables
       */
       for(itimes=1;itimes<=2;itimes++){
         jj=0;
         for(i=1; i <=nlstate; i++){
           for(j=1; j <=nlstate+ndeath; j++){
             if(j==i) continue;
             for(k=1; k<=ncovmodel;k++){
               jj++;
               ca[0]= k+'a'-1;ca[1]='\0';
               if(itimes==1){
                 if(mle>=1)
                   printf("#%1d%1d%d",i,j,k);
                 fprintf(ficlog,"#%1d%1d%d",i,j,k);
                 fprintf(ficres,"#%1d%1d%d",i,j,k);
               }else{
                 if(mle>=1)
                   printf("%1d%1d%d",i,j,k);
                 fprintf(ficlog,"%1d%1d%d",i,j,k);
                 fprintf(ficres,"%1d%1d%d",i,j,k);
               }
               ll=0;
               for(li=1;li <=nlstate; li++){
                 for(lj=1;lj <=nlstate+ndeath; lj++){
                   if(lj==li) continue;
                   for(lk=1;lk<=ncovmodel;lk++){
                     ll++;
                     if(ll<=jj){
                       cb[0]= lk +'a'-1;cb[1]='\0';
                       if(ll<jj){
                         if(itimes==1){
                           if(mle>=1)
                             printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                           fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                           fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                         }else{
                           if(mle>=1)
                             printf(" %.5e",matcov[jj][ll]); 
                           fprintf(ficlog," %.5e",matcov[jj][ll]); 
                           fprintf(ficres," %.5e",matcov[jj][ll]); 
                         }
                       }else{
                         if(itimes==1){
                           if(mle>=1)
                             printf(" Var(%s%1d%1d)",ca,i,j);
                           fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                           fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                         }else{
                           if(mle>=1)
                             printf(" %.5e",matcov[jj][ll]); 
                           fprintf(ficlog," %.5e",matcov[jj][ll]); 
                           fprintf(ficres," %.5e",matcov[jj][ll]); 
                         }
                       }
                     }
                   } /* end lk */
                 } /* end lj */
               } /* end li */
               if(mle>=1)
                 printf("\n");
               fprintf(ficlog,"\n");
               fprintf(ficres,"\n");
               numlinepar++;
             } /* end k*/
           } /*end j */
         } /* end i */
       } /* end itimes */
       
       fflush(ficlog);
       fflush(ficres);
       
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         fputs(line,stdout);
         fputs(line,ficparo);
       }
       ungetc(c,ficpar);
       
       estepm=0;
       fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm);
       if (estepm==0 || estepm < stepm) estepm=stepm;
       if (fage <= 2) {
         bage = ageminpar;
         fage = agemaxpar;
       }
       
       fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
       fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d\n",ageminpar,agemaxpar,bage,fage, estepm);
       fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d\n",ageminpar,agemaxpar,bage,fage, estepm);
       
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         fputs(line,stdout);
         fputs(line,ficparo);
       }
       ungetc(c,ficpar);
       
       fscanf(ficpar,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav);
       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
       
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         fputs(line,stdout);
         fputs(line,ficparo);
       }
       ungetc(c,ficpar);
       
       
       dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
       dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
       
       fscanf(ficpar,"pop_based=%d\n",&popbased);
       fprintf(ficparo,"pop_based=%d\n",popbased);   
       fprintf(ficres,"pop_based=%d\n",popbased);   
       
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         fputs(line,stdout);
         fputs(line,ficparo);
       }
       ungetc(c,ficpar);
       
       fscanf(ficpar,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj);
       fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
       printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
       fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
       fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
       /* day and month of proj2 are not used but only year anproj2.*/
       
       
       
        /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
       /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
       
       replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
       printinggnuplot(fileres, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
       
       printinghtml(fileres,title,datafile, firstpass, lastpass, stepm, weightopt,\
                    model,imx,jmin,jmax,jmean,rfileres,popforecast,estepm,\
                    jprev1,mprev1,anprev1,jprev2,mprev2,anprev2);
         
      /*------------ free_vector  -------------*/
      /*  chdir(path); */
    
       free_ivector(wav,1,imx);
       free_imatrix(dh,1,lastpass-firstpass+1,1,imx);
       free_imatrix(bh,1,lastpass-firstpass+1,1,imx);
       free_imatrix(mw,1,lastpass-firstpass+1,1,imx);   
       free_lvector(num,1,n);
       free_vector(agedc,1,n);
       /*free_matrix(covar,0,NCOVMAX,1,n);*/
       /*free_matrix(covar,1,NCOVMAX,1,n);*/
       fclose(ficparo);
       fclose(ficres);
   
   
       /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
   #include "prevlim.h"  /* Use ficrespl, ficlog */
       fclose(ficrespl);
   
   #ifdef FREEEXIT2
   #include "freeexit2.h"
   #endif
   
       /*------------- h Pij x at various ages ------------*/
   #include "hpijx.h"
       fclose(ficrespij);
   
     /*-------------- Variance of one-step probabilities---*/
       k=1;
       varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
   
   
       probs= ma3x(1,AGESUP,1,NCOVMAX, 1,NCOVMAX);
       for(i=1;i<=AGESUP;i++)
         for(j=1;j<=NCOVMAX;j++)
           for(k=1;k<=NCOVMAX;k++)
             probs[i][j][k]=0.;
   
       /*---------- Forecasting ------------------*/
       /*if((stepm == 1) && (strcmp(model,".")==0)){*/
       if(prevfcast==1){
         /*    if(stepm ==1){*/
         prevforecast(fileres, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
         /* (popforecast==1) populforecast(fileres, anpyram,mpyram,jpyram, agemin,agemax, dateprev1, dateprev2,mobilav, agedeb, fage, popforecast, popfile, anpyram1,p, i1);*/
         /*      }  */
         /*      else{ */
         /*        erreur=108; */
         /*        printf("Warning %d!! You can only forecast the prevalences if the optimization\n  has been performed with stepm = 1 (month) instead of %d or model=. instead of '%s'\n", erreur, stepm, model); */
         /*        fprintf(ficlog,"Warning %d!! You can only forecast the prevalences if the optimization\n  has been performed with stepm = 1 (month) instead of %d or model=. instead of '%s'\n", erreur, stepm, model); */
         /*      } */
       }
     
   
       /* Computes prevalence between agemin (i.e minimal age computed) and no more ageminpar */
   
       prevalence(probs, agemin, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
       /*  printf("ageminpar=%f, agemax=%f, s[lastpass][imx]=%d, agev[lastpass][imx]=%f, nlstate=%d, imx=%d,  mint[lastpass][imx]=%f, anint[lastpass][imx]=%f,dateprev1=%f, dateprev2=%f, firstpass=%d, lastpass=%d\n",\
           ageminpar, agemax, s[lastpass][imx], agev[lastpass][imx], nlstate, imx, mint[lastpass][imx],anint[lastpass][imx], dateprev1, dateprev2, firstpass, lastpass);
       */
   
       if (mobilav!=0) {
         mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
         if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){
           fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
           printf(" Error in movingaverage mobilav=%d\n",mobilav);
         }
       }
   
   
       /*---------- Health expectancies, no variances ------------*/
   
       strcpy(filerese,"e");
       strcat(filerese,fileres);
       if((ficreseij=fopen(filerese,"w"))==NULL) {
         printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
         fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
       }
       printf("Computing Health Expectancies: result on file '%s' \n", filerese);
       fprintf(ficlog,"Computing Health Expectancies: result on file '%s' \n", filerese);
       /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
         for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
             
       for (k=1; k <= (int) pow(2,cptcoveff); k++){
           fprintf(ficreseij,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) {
             fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
           }
           fprintf(ficreseij,"******\n");
   
           eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
           oldm=oldms;savm=savms;
           evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart);  
         
           free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
         /*}*/
       }
       fclose(ficreseij);
   
   
       /*---------- Health expectancies and variances ------------*/
   
   
       strcpy(filerest,"t");
       strcat(filerest,fileres);
       if((ficrest=fopen(filerest,"w"))==NULL) {
         printf("Problem with total LE resultfile: %s\n", filerest);goto end;
         fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
       }
       printf("Computing Total Life expectancies with their standard errors: file '%s' \n", filerest); 
       fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' \n", filerest); 
   
   
       strcpy(fileresstde,"stde");
       strcat(fileresstde,fileres);
       if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
         printf("Problem with Health Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
         fprintf(ficlog,"Problem with Health Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
       }
       printf("Computing Health Expectancies and standard errors: result on file '%s' \n", fileresstde);
       fprintf(ficlog,"Computing Health Expectancies and standard errors: result on file '%s' \n", fileresstde);
   
       strcpy(filerescve,"cve");
       strcat(filerescve,fileres);
       if((ficrescveij=fopen(filerescve,"w"))==NULL) {
         printf("Problem with Covar. Health Exp. resultfile: %s\n", filerescve); exit(0);
         fprintf(ficlog,"Problem with Covar. Health Exp. resultfile: %s\n", filerescve); exit(0);
       }
       printf("Computing Covar. of Health Expectancies: result on file '%s' \n", filerescve);
       fprintf(ficlog,"Computing Covar. of Health Expectancies: result on file '%s' \n", filerescve);
   
       strcpy(fileresv,"v");
       strcat(fileresv,fileres);
       if((ficresvij=fopen(fileresv,"w"))==NULL) {
         printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
         fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
       }
       printf("Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);
       fprintf(ficlog,"Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);
   
       /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
         for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
             
       for (k=1; k <= (int) pow(2,cptcoveff); k++){
           fprintf(ficrest,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) 
             fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
           fprintf(ficrest,"******\n");
   
           fprintf(ficresstdeij,"\n#****** ");
           fprintf(ficrescveij,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) {
             fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
             fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
           }
           fprintf(ficresstdeij,"******\n");
           fprintf(ficrescveij,"******\n");
   
           fprintf(ficresvij,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) 
             fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
           fprintf(ficresvij,"******\n");
   
           eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
           oldm=oldms;savm=savms;
           cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart);  
           /*
            */
           /* goto endfree; */
    
           vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
           pstamp(ficrest);
   
   
           for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
             oldm=oldms;savm=savms; /* Segmentation fault */
             varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart);
             fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
             if(vpopbased==1)
               fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
             else
               fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
             fprintf(ficrest,"# Age e.. (std) ");
             for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
             fprintf(ficrest,"\n");
   
             epj=vector(1,nlstate+1);
             for(age=bage; age <=fage ;age++){
               prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);
               if (vpopbased==1) {
                 if(mobilav ==0){
                   for(i=1; i<=nlstate;i++)
                     prlim[i][i]=probs[(int)age][i][k];
                 }else{ /* mobilav */ 
                   for(i=1; i<=nlstate;i++)
                     prlim[i][i]=mobaverage[(int)age][i][k];
                 }
               }
           
               fprintf(ficrest," %4.0f",age);
               for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                 for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   /*  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                 }
                 epj[nlstate+1] +=epj[j];
               }
   
               for(i=1, vepp=0.;i <=nlstate;i++)
                 for(j=1;j <=nlstate;j++)
                   vepp += vareij[i][j][(int)age];
               fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
               for(j=1;j <=nlstate;j++){
                 fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
               }
               fprintf(ficrest,"\n");
             }
           }
           free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
           free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
           free_vector(epj,1,nlstate+1);
         /*}*/
       }
       free_vector(weight,1,n);
       free_imatrix(Tvard,1,NCOVMAX,1,2);
       free_imatrix(s,1,maxwav+1,1,n);
       free_matrix(anint,1,maxwav,1,n); 
       free_matrix(mint,1,maxwav,1,n);
       free_ivector(cod,1,n);
       free_ivector(tab,1,NCOVMAX);
       fclose(ficresstdeij);
       fclose(ficrescveij);
       fclose(ficresvij);
       fclose(ficrest);
       fclose(ficpar);
     
       /*------- Variance of period (stable) prevalence------*/   
   
       strcpy(fileresvpl,"vpl");
       strcat(fileresvpl,fileres);
       if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
         printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
         exit(0);
       }
       printf("Computing Variance-covariance of period (stable) prevalence: file '%s' \n", fileresvpl);
   
       /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
         for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
             
       for (k=1; k <= (int) pow(2,cptcoveff); k++){
           fprintf(ficresvpl,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) 
             fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
           fprintf(ficresvpl,"******\n");
         
           varpl=matrix(1,nlstate,(int) bage, (int) fage);
           oldm=oldms;savm=savms;
           varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k,strstart);
           free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
         /*}*/
       }
   
       fclose(ficresvpl);
   
       /*---------- End : free ----------------*/
       if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       free_ma3x(probs,1,AGESUP,1,NCOVMAX, 1,NCOVMAX);
     }  /* mle==-3 arrives here for freeing */
    endfree:
       free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
       free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
       free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
       free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
       free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
       free_matrix(covar,0,NCOVMAX,1,n);
       free_matrix(matcov,1,npar,1,npar);
       /*free_vector(delti,1,npar);*/
       free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
       free_matrix(agev,1,maxwav,1,imx);
       free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
   
       free_ivector(ncodemax,1,NCOVMAX);
       free_ivector(Tvar,1,NCOVMAX);
       free_ivector(Tprod,1,NCOVMAX);
       free_ivector(Tvaraff,1,NCOVMAX);
       free_ivector(Tage,1,NCOVMAX);
   
       free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
       free_imatrix(codtab,1,100,1,10);
     fflush(fichtm);
     fflush(ficgp);
     
   
     if((nberr >0) || (nbwarn>0)){
       printf("End of Imach with %d errors and/or %d warnings\n",nberr,nbwarn);
       fprintf(ficlog,"End of Imach with %d errors and/or warnings %d\n",nberr,nbwarn);
     }else{
       printf("End of Imach\n");
       fprintf(ficlog,"End of Imach\n");
     }
     printf("See log file on %s\n",filelog);
     /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
     (void) gettimeofday(&end_time,&tzp);
     tm = *localtime(&end_time.tv_sec);
     tmg = *gmtime(&end_time.tv_sec);
     strcpy(strtend,asctime(&tm));
     printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
     fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
     printf("Total time used %s\n", asc_diff_time(end_time.tv_sec -start_time.tv_sec,tmpout));
   
     printf("Total time was %ld Sec.\n", end_time.tv_sec -start_time.tv_sec);
     fprintf(ficlog,"Total time used %s\n", asc_diff_time(end_time.tv_sec -start_time.tv_sec,tmpout));
     fprintf(ficlog,"Total time was %ld Sec.\n", end_time.tv_sec -start_time.tv_sec);
     /*  printf("Total time was %d uSec.\n", total_usecs);*/
   /*   if(fileappend(fichtm,optionfilehtm)){ */
     fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
     fclose(fichtm);
     fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
     fclose(fichtmcov);
     fclose(ficgp);
     fclose(ficlog);
     /*------ End -----------*/
   
   
      printf("Before Current directory %s!\n",pathcd);
      if(chdir(pathcd) != 0)
       printf("Can't move to directory %s!\n",path);
     if(getcwd(pathcd,MAXLINE) > 0)
       printf("Current directory %s!\n",pathcd);
     /*strcat(plotcmd,CHARSEPARATOR);*/
     sprintf(plotcmd,"gnuplot");
   #ifndef UNIX
     sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
   #endif
     if(!stat(plotcmd,&info)){
       printf("Error gnuplot program not found: %s\n",plotcmd);fflush(stdout);
       if(!stat(getenv("GNUPLOTBIN"),&info)){
         printf("Error gnuplot program not found: %s Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
       }else
         strcpy(pplotcmd,plotcmd);
   #ifdef UNIX
       strcpy(plotcmd,GNUPLOTPROGRAM);
       if(!stat(plotcmd,&info)){
         printf("Error gnuplot program not found: %s\n",plotcmd);fflush(stdout);
       }else
         strcpy(pplotcmd,plotcmd);
   #endif
     }else
       strcpy(pplotcmd,plotcmd);
     
     sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
     printf("Starting graphs with: %s\n",plotcmd);fflush(stdout);
   
     if((outcmd=system(plotcmd)) != 0){
       printf("\n Problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
       printf("\n Trying on same directory\n");
       sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
       if((outcmd=system(plotcmd)) != 0)
         printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
     }
     printf(" Wait...");
     while (z[0] != 'q') {
       /* chdir(path); */
       printf("\nType e to edit output files, g to graph again and q for exiting: ");
       scanf("%s",z);
   /*     if (z[0] == 'c') system("./imach"); */
       if (z[0] == 'e') {
   #ifdef OSX
         sprintf(pplotcmd, "open %s", optionfilehtm);
   #else
         sprintf(pplotcmd, "%s", optionfilehtm);
   #endif
         printf("Starting browser with: %s",pplotcmd);fflush(stdout);
         system(pplotcmd);
       }
       else if (z[0] == 'g') system(plotcmd);
       else if (z[0] == 'q') exit(0);
     }
     end:
     while (z[0] != 'q') {
       printf("\nType  q for exiting: ");
       scanf("%s",z);
     }
   }
   
   
   

Removed from v.1.14  
changed lines
  Added in v.1.153


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