Diff for /imach/src/imach.c between versions 1.8 and 1.160

version 1.8, 2001/05/02 17:54:31 version 1.160, 2014/09/02 09:24:05
Line 1 Line 1
      /* $Id$
 /*********************** Imach **************************************            $State$
   This program computes Healthy Life Expectancies from cross-longitudinal    $Log$
   data. Cross-longitudinal consist in a first survey ("cross") where    Revision 1.160  2014/09/02 09:24:05  brouard
   individuals from different ages are interviewed on their health status    *** empty log message ***
   or degree of  disability. At least a second wave of interviews  
   ("longitudinal") should  measure each new individual health status.    Revision 1.159  2014/09/01 10:34:10  brouard
   Health expectancies are computed from the transistions observed between    Summary: WIN32
   waves and are computed for each degree of severity of disability (number    Author: Brouard
   of life states). More degrees you consider, more time is necessary to  
   reach the Maximum Likelihood of the parameters involved in the model.    Revision 1.158  2014/08/27 17:11:51  brouard
   The simplest model is the multinomial logistic model where pij is    *** empty log message ***
   the probabibility to be observed in state j at the second wave conditional  
   to be observed in state i at the first wave. Therefore the model is:    Revision 1.157  2014/08/27 16:26:55  brouard
   log(pij/pii)= aij + bij*age+ cij*sex + etc , where 'age' is age and 'sex'    Summary: Preparing windows Visual studio version
   is a covariate. If you want to have a more complex model than "constant and    Author: Brouard
   age", you should modify the program where the markup  
     *Covariates have to be included here again* invites you to do it.    In order to compile on Visual studio, time.h is now correct and time_t
   More covariates you add, less is the speed of the convergence.    and tm struct should be used. difftime should be used but sometimes I
     just make the differences in raw time format (time(&now).
   The advantage that this computer programme claims, comes from that if the    Trying to suppress #ifdef LINUX
   delay between waves is not identical for each individual, or if some    Add xdg-open for __linux in order to open default browser.
   individual missed an interview, the information is not rounded or lost, but  
   taken into account using an interpolation or extrapolation.    Revision 1.156  2014/08/25 20:10:10  brouard
   hPijx is the probability to be    *** empty log message ***
   observed in state i at age x+h conditional to the observed state i at age  
   x. The delay 'h' can be split into an exact number (nh*stepm) of    Revision 1.155  2014/08/25 18:32:34  brouard
   unobserved intermediate  states. This elementary transition (by month or    Summary: New compile, minor changes
   quarter trimester, semester or year) is model as a multinomial logistic.    Author: Brouard
   The hPx matrix is simply the matrix product of nh*stepm elementary matrices  
   and the contribution of each individual to the likelihood is simply hPijx.    Revision 1.154  2014/06/20 17:32:08  brouard
     Summary: Outputs now all graphs of convergence to period prevalence
   Also this programme outputs the covariance matrix of the parameters but also  
   of the life expectancies. It also computes the prevalence limits.    Revision 1.153  2014/06/20 16:45:46  brouard
      Summary: If 3 live state, convergence to period prevalence on same graph
   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).    Author: Brouard
            Institut national d'études démographiques, Paris.  
   This software have been partly granted by Euro-REVES, a concerted action    Revision 1.152  2014/06/18 17:54:09  brouard
   from the European Union.    Summary: open browser, use gnuplot on same dir than imach if not found in the path
   It is copyrighted identically to a GNU software product, ie programme and  
   software can be distributed freely for non commercial use. Latest version    Revision 1.151  2014/06/18 16:43:30  brouard
   can be accessed at http://euroreves.ined.fr/imach .    *** empty log message ***
   **********************************************************************/  
      Revision 1.150  2014/06/18 16:42:35  brouard
 #include <math.h>    Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
 #include <stdio.h>    Author: brouard
 #include <stdlib.h>  
 #include <unistd.h>    Revision 1.149  2014/06/18 15:51:14  brouard
     Summary: Some fixes in parameter files errors
 #define MAXLINE 256    Author: Nicolas Brouard
 #define FILENAMELENGTH 80  
 /*#define DEBUG*/    Revision 1.148  2014/06/17 17:38:48  brouard
 #define windows    Summary: Nothing new
 #define GLOCK_ERROR_NOPATH              -1      /* empty path */    Author: Brouard
 #define GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */  
     Just a new packaging for OS/X version 0.98nS
 #define MAXPARM 30 /* Maximum number of parameters for the optimization */  
 #define NPARMAX 64 /* (nlstate+ndeath-1)*nlstate*ncovmodel */    Revision 1.147  2014/06/16 10:33:11  brouard
     *** empty log message ***
 #define NINTERVMAX 8  
 #define NLSTATEMAX 8 /* Maximum number of live states (for func) */    Revision 1.146  2014/06/16 10:20:28  brouard
 #define NDEATHMAX 8 /* Maximum number of dead states (for func) */    Summary: Merge
 #define NCOVMAX 8 /* Maximum number of covariates */    Author: Brouard
 #define MAXN 20000  
 #define YEARM 12. /* Number of months per year */    Merge, before building revised version.
 #define AGESUP 130  
 #define AGEBASE 40    Revision 1.145  2014/06/10 21:23:15  brouard
     Summary: Debugging with valgrind
     Author: Nicolas Brouard
 int nvar;  
 int cptcovn, cptcovage=0, cptcoveff=0,cptcov;    Lot of changes in order to output the results with some covariates
 int npar=NPARMAX;    After the Edimburgh REVES conference 2014, it seems mandatory to
 int nlstate=2; /* Number of live states */    improve the code.
 int ndeath=1; /* Number of dead states */    No more memory valgrind error but a lot has to be done in order to
 int ncovmodel, ncov;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */    continue the work of splitting the code into subroutines.
     Also, decodemodel has been improved. Tricode is still not
 int *wav; /* Number of waves for this individuual 0 is possible */    optimal. nbcode should be improved. Documentation has been added in
 int maxwav; /* Maxim number of waves */    the source code.
 int jmin, jmax; /* min, max spacing between 2 waves */  
 int mle, weightopt;    Revision 1.143  2014/01/26 09:45:38  brouard
 int **mw; /* mw[mi][i] is number of the mi wave for this individual */    Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
 int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */  
 double jmean; /* Mean space between 2 waves */    * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
 double **oldm, **newm, **savm; /* Working pointers to matrices */    (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
 double **oldms, **newms, **savms; /* Fixed working pointers to matrices */  
 FILE *fic,*ficpar, *ficparo,*ficres,  *ficrespl, *ficrespij, *ficrest;    Revision 1.142  2014/01/26 03:57:36  brouard
 FILE *ficgp, *fichtm;    Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
 FILE *ficreseij;  
   char filerese[FILENAMELENGTH];    * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
  FILE  *ficresvij;  
   char fileresv[FILENAMELENGTH];    Revision 1.141  2014/01/26 02:42:01  brouard
  FILE  *ficresvpl;    * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
   char fileresvpl[FILENAMELENGTH];  
     Revision 1.140  2011/09/02 10:37:54  brouard
 #define NR_END 1    Summary: times.h is ok with mingw32 now.
 #define FREE_ARG char*  
 #define FTOL 1.0e-10    Revision 1.139  2010/06/14 07:50:17  brouard
     After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
 #define NRANSI    I remember having already fixed agemin agemax which are pointers now but not cvs saved.
 #define ITMAX 200  
     Revision 1.138  2010/04/30 18:19:40  brouard
 #define TOL 2.0e-4    *** empty log message ***
   
 #define CGOLD 0.3819660    Revision 1.137  2010/04/29 18:11:38  brouard
 #define ZEPS 1.0e-10    (Module): Checking covariates for more complex models
 #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d);    than V1+V2. A lot of change to be done. Unstable.
   
 #define GOLD 1.618034    Revision 1.136  2010/04/26 20:30:53  brouard
 #define GLIMIT 100.0    (Module): merging some libgsl code. Fixing computation
 #define TINY 1.0e-20    of likelione (using inter/intrapolation if mle = 0) in order to
     get same likelihood as if mle=1.
 static double maxarg1,maxarg2;    Some cleaning of code and comments added.
 #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))  
 #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))    Revision 1.135  2009/10/29 15:33:14  brouard
      (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
 #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))  
 #define rint(a) floor(a+0.5)    Revision 1.134  2009/10/29 13:18:53  brouard
     (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
 static double sqrarg;  
 #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)    Revision 1.133  2009/07/06 10:21:25  brouard
 #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;}    just nforces
   
 int imx;    Revision 1.132  2009/07/06 08:22:05  brouard
 int stepm;    Many tings
 /* Stepm, step in month: minimum step interpolation*/  
     Revision 1.131  2009/06/20 16:22:47  brouard
 int m,nb;    Some dimensions resccaled
 int *num, firstpass=0, lastpass=4,*cod, *ncodemax, *Tage;  
 double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;    Revision 1.130  2009/05/26 06:44:34  brouard
 double **pmmij;    (Module): Max Covariate is now set to 20 instead of 8. A
     lot of cleaning with variables initialized to 0. Trying to make
 double *weight;    V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
 int **s; /* Status */  
 double *agedc, **covar, idx;    Revision 1.129  2007/08/31 13:49:27  lievre
 int **nbcode, *Tcode, *Tvar, **codtab, **Tvard, *Tprod, cptcovprod, *Tvaraff;    Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
   
 double ftol=FTOL; /* Tolerance for computing Max Likelihood */    Revision 1.128  2006/06/30 13:02:05  brouard
 double ftolhess; /* Tolerance for computing hessian */    (Module): Clarifications on computing e.j
   
 /**************** split *************************/    Revision 1.127  2006/04/28 18:11:50  brouard
 static  int split( char *path, char *dirc, char *name )    (Module): Yes the sum of survivors was wrong since
 {    imach-114 because nhstepm was no more computed in the age
    char *s;                             /* pointer */    loop. Now we define nhstepma in the age loop.
    int  l1, l2;                         /* length counters */    (Module): In order to speed up (in case of numerous covariates) we
     compute health expectancies (without variances) in a first step
    l1 = strlen( path );                 /* length of path */    and then all the health expectancies with variances or standard
    if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );    deviation (needs data from the Hessian matrices) which slows the
    s = strrchr( path, '\\' );           /* find last / */    computation.
    if ( s == NULL ) {                   /* no directory, so use current */    In the future we should be able to stop the program is only health
 #if     defined(__bsd__)                /* get current working directory */    expectancies and graph are needed without standard deviations.
       extern char       *getwd( );  
     Revision 1.126  2006/04/28 17:23:28  brouard
       if ( getwd( dirc ) == NULL ) {    (Module): Yes the sum of survivors was wrong since
 #else    imach-114 because nhstepm was no more computed in the age
       extern char       *getcwd( );    loop. Now we define nhstepma in the age loop.
     Version 0.98h
       if ( getcwd( dirc, FILENAME_MAX ) == NULL ) {  
 #endif    Revision 1.125  2006/04/04 15:20:31  lievre
          return( GLOCK_ERROR_GETCWD );    Errors in calculation of health expectancies. Age was not initialized.
       }    Forecasting file added.
       strcpy( name, path );             /* we've got it */  
    } else {                             /* strip direcotry from path */    Revision 1.124  2006/03/22 17:13:53  lievre
       s++;                              /* after this, the filename */    Parameters are printed with %lf instead of %f (more numbers after the comma).
       l2 = strlen( s );                 /* length of filename */    The log-likelihood is printed in the log file
       if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );  
       strcpy( name, s );                /* save file name */    Revision 1.123  2006/03/20 10:52:43  brouard
       strncpy( dirc, path, l1 - l2 );   /* now the directory */    * imach.c (Module): <title> changed, corresponds to .htm file
       dirc[l1-l2] = 0;                  /* add zero */    name. <head> headers where missing.
    }  
    l1 = strlen( dirc );                 /* length of directory */    * imach.c (Module): Weights can have a decimal point as for
    if ( dirc[l1-1] != '\\' ) { dirc[l1] = '\\'; dirc[l1+1] = 0; }    English (a comma might work with a correct LC_NUMERIC environment,
    return( 0 );                         /* we're done */    otherwise the weight is truncated).
 }    Modification of warning when the covariates values are not 0 or
     1.
     Version 0.98g
 /******************************************/  
     Revision 1.122  2006/03/20 09:45:41  brouard
 void replace(char *s, char*t)    (Module): Weights can have a decimal point as for
 {    English (a comma might work with a correct LC_NUMERIC environment,
   int i;    otherwise the weight is truncated).
   int lg=20;    Modification of warning when the covariates values are not 0 or
   i=0;    1.
   lg=strlen(t);    Version 0.98g
   for(i=0; i<= lg; i++) {  
     (s[i] = t[i]);    Revision 1.121  2006/03/16 17:45:01  lievre
     if (t[i]== '\\') s[i]='/';    * imach.c (Module): Comments concerning covariates added
   }  
 }    * imach.c (Module): refinements in the computation of lli if
     status=-2 in order to have more reliable computation if stepm is
 int nbocc(char *s, char occ)    not 1 month. Version 0.98f
 {  
   int i,j=0;    Revision 1.120  2006/03/16 15:10:38  lievre
   int lg=20;    (Module): refinements in the computation of lli if
   i=0;    status=-2 in order to have more reliable computation if stepm is
   lg=strlen(s);    not 1 month. Version 0.98f
   for(i=0; i<= lg; i++) {  
   if  (s[i] == occ ) j++;    Revision 1.119  2006/03/15 17:42:26  brouard
   }    (Module): Bug if status = -2, the loglikelihood was
   return j;    computed as likelihood omitting the logarithm. Version O.98e
 }  
     Revision 1.118  2006/03/14 18:20:07  brouard
 void cutv(char *u,char *v, char*t, char occ)    (Module): varevsij Comments added explaining the second
 {    table of variances if popbased=1 .
   int i,lg,j,p=0;    (Module): Covariances of eij, ekl added, graphs fixed, new html link.
   i=0;    (Module): Function pstamp added
   for(j=0; j<=strlen(t)-1; j++) {    (Module): Version 0.98d
     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1;  
   }    Revision 1.117  2006/03/14 17:16:22  brouard
     (Module): varevsij Comments added explaining the second
   lg=strlen(t);    table of variances if popbased=1 .
   for(j=0; j<p; j++) {    (Module): Covariances of eij, ekl added, graphs fixed, new html link.
     (u[j] = t[j]);    (Module): Function pstamp added
   }    (Module): Version 0.98d
      u[p]='\0';  
     Revision 1.116  2006/03/06 10:29:27  brouard
    for(j=0; j<= lg; j++) {    (Module): Variance-covariance wrong links and
     if (j>=(p+1))(v[j-p-1] = t[j]);    varian-covariance of ej. is needed (Saito).
   }  
 }    Revision 1.115  2006/02/27 12:17:45  brouard
     (Module): One freematrix added in mlikeli! 0.98c
 /********************** nrerror ********************/  
     Revision 1.114  2006/02/26 12:57:58  brouard
 void nrerror(char error_text[])    (Module): Some improvements in processing parameter
 {    filename with strsep.
   fprintf(stderr,"ERREUR ...\n");  
   fprintf(stderr,"%s\n",error_text);    Revision 1.113  2006/02/24 14:20:24  brouard
   exit(1);    (Module): Memory leaks checks with valgrind and:
 }    datafile was not closed, some imatrix were not freed and on matrix
 /*********************** vector *******************/    allocation too.
 double *vector(int nl, int nh)  
 {    Revision 1.112  2006/01/30 09:55:26  brouard
   double *v;    (Module): Back to gnuplot.exe instead of wgnuplot.exe
   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));  
   if (!v) nrerror("allocation failure in vector");    Revision 1.111  2006/01/25 20:38:18  brouard
   return v-nl+NR_END;    (Module): Lots of cleaning and bugs added (Gompertz)
 }    (Module): Comments can be added in data file. Missing date values
     can be a simple dot '.'.
 /************************ free vector ******************/  
 void free_vector(double*v, int nl, int nh)    Revision 1.110  2006/01/25 00:51:50  brouard
 {    (Module): Lots of cleaning and bugs added (Gompertz)
   free((FREE_ARG)(v+nl-NR_END));  
 }    Revision 1.109  2006/01/24 19:37:15  brouard
     (Module): Comments (lines starting with a #) are allowed in data.
 /************************ivector *******************************/  
 int *ivector(long nl,long nh)    Revision 1.108  2006/01/19 18:05:42  lievre
 {    Gnuplot problem appeared...
   int *v;    To be fixed
   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));  
   if (!v) nrerror("allocation failure in ivector");    Revision 1.107  2006/01/19 16:20:37  brouard
   return v-nl+NR_END;    Test existence of gnuplot in imach path
 }  
     Revision 1.106  2006/01/19 13:24:36  brouard
 /******************free ivector **************************/    Some cleaning and links added in html output
 void free_ivector(int *v, long nl, long nh)  
 {    Revision 1.105  2006/01/05 20:23:19  lievre
   free((FREE_ARG)(v+nl-NR_END));    *** empty log message ***
 }  
     Revision 1.104  2005/09/30 16:11:43  lievre
 /******************* imatrix *******************************/    (Module): sump fixed, loop imx fixed, and simplifications.
 int **imatrix(long nrl, long nrh, long ncl, long nch)    (Module): If the status is missing at the last wave but we know
      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */    that the person is alive, then we can code his/her status as -2
 {    (instead of missing=-1 in earlier versions) and his/her
   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1;    contributions to the likelihood is 1 - Prob of dying from last
   int **m;    health status (= 1-p13= p11+p12 in the easiest case of somebody in
      the healthy state at last known wave). Version is 0.98
   /* allocate pointers to rows */  
   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*)));    Revision 1.103  2005/09/30 15:54:49  lievre
   if (!m) nrerror("allocation failure 1 in matrix()");    (Module): sump fixed, loop imx fixed, and simplifications.
   m += NR_END;  
   m -= nrl;    Revision 1.102  2004/09/15 17:31:30  brouard
      Add the possibility to read data file including tab characters.
    
   /* allocate rows and set pointers to them */    Revision 1.101  2004/09/15 10:38:38  brouard
   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int)));    Fix on curr_time
   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");  
   m[nrl] += NR_END;    Revision 1.100  2004/07/12 18:29:06  brouard
   m[nrl] -= ncl;    Add version for Mac OS X. Just define UNIX in Makefile
    
   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol;    Revision 1.99  2004/06/05 08:57:40  brouard
      *** empty log message ***
   /* return pointer to array of pointers to rows */  
   return m;    Revision 1.98  2004/05/16 15:05:56  brouard
 }    New version 0.97 . First attempt to estimate force of mortality
     directly from the data i.e. without the need of knowing the health
 /****************** free_imatrix *************************/    state at each age, but using a Gompertz model: log u =a + b*age .
 void free_imatrix(m,nrl,nrh,ncl,nch)    This is the basic analysis of mortality and should be done before any
       int **m;    other analysis, in order to test if the mortality estimated from the
       long nch,ncl,nrh,nrl;    cross-longitudinal survey is different from the mortality estimated
      /* free an int matrix allocated by imatrix() */    from other sources like vital statistic data.
 {  
   free((FREE_ARG) (m[nrl]+ncl-NR_END));    The same imach parameter file can be used but the option for mle should be -3.
   free((FREE_ARG) (m+nrl-NR_END));  
 }    Agnès, who wrote this part of the code, tried to keep most of the
     former routines in order to include the new code within the former code.
 /******************* matrix *******************************/  
 double **matrix(long nrl, long nrh, long ncl, long nch)    The output is very simple: only an estimate of the intercept and of
 {    the slope with 95% confident intervals.
   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;  
   double **m;    Current limitations:
     A) Even if you enter covariates, i.e. with the
   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));    model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
   if (!m) nrerror("allocation failure 1 in matrix()");    B) There is no computation of Life Expectancy nor Life Table.
   m += NR_END;  
   m -= nrl;    Revision 1.97  2004/02/20 13:25:42  lievre
     Version 0.96d. Population forecasting command line is (temporarily)
   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));    suppressed.
   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");  
   m[nrl] += NR_END;    Revision 1.96  2003/07/15 15:38:55  brouard
   m[nrl] -= ncl;    * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
     rewritten within the same printf. Workaround: many printfs.
   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;  
   return m;    Revision 1.95  2003/07/08 07:54:34  brouard
 }    * imach.c (Repository):
     (Repository): Using imachwizard code to output a more meaningful covariance
 /*************************free matrix ************************/    matrix (cov(a12,c31) instead of numbers.
 void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)  
 {    Revision 1.94  2003/06/27 13:00:02  brouard
   free((FREE_ARG)(m[nrl]+ncl-NR_END));    Just cleaning
   free((FREE_ARG)(m+nrl-NR_END));  
 }    Revision 1.93  2003/06/25 16:33:55  brouard
     (Module): On windows (cygwin) function asctime_r doesn't
 /******************* ma3x *******************************/    exist so I changed back to asctime which exists.
 double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)    (Module): Version 0.96b
 {  
   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;    Revision 1.92  2003/06/25 16:30:45  brouard
   double ***m;    (Module): On windows (cygwin) function asctime_r doesn't
     exist so I changed back to asctime which exists.
   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));  
   if (!m) nrerror("allocation failure 1 in matrix()");    Revision 1.91  2003/06/25 15:30:29  brouard
   m += NR_END;    * imach.c (Repository): Duplicated warning errors corrected.
   m -= nrl;    (Repository): Elapsed time after each iteration is now output. It
     helps to forecast when convergence will be reached. Elapsed time
   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));    is stamped in powell.  We created a new html file for the graphs
   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");    concerning matrix of covariance. It has extension -cov.htm.
   m[nrl] += NR_END;  
   m[nrl] -= ncl;    Revision 1.90  2003/06/24 12:34:15  brouard
     (Module): Some bugs corrected for windows. Also, when
   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;    mle=-1 a template is output in file "or"mypar.txt with the design
     of the covariance matrix to be input.
   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));  
   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");    Revision 1.89  2003/06/24 12:30:52  brouard
   m[nrl][ncl] += NR_END;    (Module): Some bugs corrected for windows. Also, when
   m[nrl][ncl] -= nll;    mle=-1 a template is output in file "or"mypar.txt with the design
   for (j=ncl+1; j<=nch; j++)    of the covariance matrix to be input.
     m[nrl][j]=m[nrl][j-1]+nlay;  
      Revision 1.88  2003/06/23 17:54:56  brouard
   for (i=nrl+1; i<=nrh; i++) {    * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;  
     for (j=ncl+1; j<=nch; j++)    Revision 1.87  2003/06/18 12:26:01  brouard
       m[i][j]=m[i][j-1]+nlay;    Version 0.96
   }  
   return m;    Revision 1.86  2003/06/17 20:04:08  brouard
 }    (Module): Change position of html and gnuplot routines and added
     routine fileappend.
 /*************************free ma3x ************************/  
 void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)    Revision 1.85  2003/06/17 13:12:43  brouard
 {    * imach.c (Repository): Check when date of death was earlier that
   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));    current date of interview. It may happen when the death was just
   free((FREE_ARG)(m[nrl]+ncl-NR_END));    prior to the death. In this case, dh was negative and likelihood
   free((FREE_ARG)(m+nrl-NR_END));    was wrong (infinity). We still send an "Error" but patch by
 }    assuming that the date of death was just one stepm after the
     interview.
 /***************** f1dim *************************/    (Repository): Because some people have very long ID (first column)
 extern int ncom;    we changed int to long in num[] and we added a new lvector for
 extern double *pcom,*xicom;    memory allocation. But we also truncated to 8 characters (left
 extern double (*nrfunc)(double []);    truncation)
      (Repository): No more line truncation errors.
 double f1dim(double x)  
 {    Revision 1.84  2003/06/13 21:44:43  brouard
   int j;    * imach.c (Repository): Replace "freqsummary" at a correct
   double f;    place. It differs from routine "prevalence" which may be called
   double *xt;    many times. Probs is memory consuming and must be used with
      parcimony.
   xt=vector(1,ncom);    Version 0.95a3 (should output exactly the same maximization than 0.8a2)
   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j];  
   f=(*nrfunc)(xt);    Revision 1.83  2003/06/10 13:39:11  lievre
   free_vector(xt,1,ncom);    *** empty log message ***
   return f;  
 }    Revision 1.82  2003/06/05 15:57:20  brouard
     Add log in  imach.c and  fullversion number is now printed.
 /*****************brent *************************/  
 double brent(double ax, double bx, double cx, double (*f)(double), double tol,  double *xmin)  */
 {  /*
   int iter;     Interpolated Markov Chain
   double a,b,d,etemp;  
   double fu,fv,fw,fx;    Short summary of the programme:
   double ftemp;    
   double p,q,r,tol1,tol2,u,v,w,x,xm;    This program computes Healthy Life Expectancies from
   double e=0.0;    cross-longitudinal data. Cross-longitudinal data consist in: -1- a
      first survey ("cross") where individuals from different ages are
   a=(ax < cx ? ax : cx);    interviewed on their health status or degree of disability (in the
   b=(ax > cx ? ax : cx);    case of a health survey which is our main interest) -2- at least a
   x=w=v=bx;    second wave of interviews ("longitudinal") which measure each change
   fw=fv=fx=(*f)(x);    (if any) in individual health status.  Health expectancies are
   for (iter=1;iter<=ITMAX;iter++) {    computed from the time spent in each health state according to a
     xm=0.5*(a+b);    model. More health states you consider, more time is necessary to reach the
     tol2=2.0*(tol1=tol*fabs(x)+ZEPS);    Maximum Likelihood of the parameters involved in the model.  The
     /*          if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/    simplest model is the multinomial logistic model where pij is the
     printf(".");fflush(stdout);    probability to be observed in state j at the second wave
 #ifdef DEBUG    conditional to be observed in state i at the first wave. Therefore
     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);    the model is: log(pij/pii)= aij + bij*age+ cij*sex + etc , where
     /*          if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */    'age' is age and 'sex' is a covariate. If you want to have a more
 #endif    complex model than "constant and age", you should modify the program
     if (fabs(x-xm) <= (tol2-0.5*(b-a))){    where the markup *Covariates have to be included here again* invites
       *xmin=x;    you to do it.  More covariates you add, slower the
       return fx;    convergence.
     }  
     ftemp=fu;    The advantage of this computer programme, compared to a simple
     if (fabs(e) > tol1) {    multinomial logistic model, is clear when the delay between waves is not
       r=(x-w)*(fx-fv);    identical for each individual. Also, if a individual missed an
       q=(x-v)*(fx-fw);    intermediate interview, the information is lost, but taken into
       p=(x-v)*q-(x-w)*r;    account using an interpolation or extrapolation.  
       q=2.0*(q-r);  
       if (q > 0.0) p = -p;    hPijx is the probability to be observed in state i at age x+h
       q=fabs(q);    conditional to the observed state i at age x. The delay 'h' can be
       etemp=e;    split into an exact number (nh*stepm) of unobserved intermediate
       e=d;    states. This elementary transition (by month, quarter,
       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x))    semester or year) is modelled as a multinomial logistic.  The hPx
         d=CGOLD*(e=(x >= xm ? a-x : b-x));    matrix is simply the matrix product of nh*stepm elementary matrices
       else {    and the contribution of each individual to the likelihood is simply
         d=p/q;    hPijx.
         u=x+d;  
         if (u-a < tol2 || b-u < tol2)    Also this programme outputs the covariance matrix of the parameters but also
           d=SIGN(tol1,xm-x);    of the life expectancies. It also computes the period (stable) prevalence. 
       }    
     } else {    Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
       d=CGOLD*(e=(x >= xm ? a-x : b-x));             Institut national d'études démographiques, Paris.
     }    This software have been partly granted by Euro-REVES, a concerted action
     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d));    from the European Union.
     fu=(*f)(u);    It is copyrighted identically to a GNU software product, ie programme and
     if (fu <= fx) {    software can be distributed freely for non commercial use. Latest version
       if (u >= x) a=x; else b=x;    can be accessed at http://euroreves.ined.fr/imach .
       SHFT(v,w,x,u)  
         SHFT(fv,fw,fx,fu)    Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
         } else {    or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
           if (u < x) a=u; else b=u;    
           if (fu <= fw || w == x) {    **********************************************************************/
             v=w;  /*
             w=u;    main
             fv=fw;    read parameterfile
             fw=fu;    read datafile
           } else if (fu <= fv || v == x || v == w) {    concatwav
             v=u;    freqsummary
             fv=fu;    if (mle >= 1)
           }      mlikeli
         }    print results files
   }    if mle==1 
   nrerror("Too many iterations in brent");       computes hessian
   *xmin=x;    read end of parameter file: agemin, agemax, bage, fage, estepm
   return fx;        begin-prev-date,...
 }    open gnuplot file
     open html file
 /****************** mnbrak ***********************/    period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
      for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
 void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc,                                    | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
             double (*func)(double))      freexexit2 possible for memory heap.
 {  
   double ulim,u,r,q, dum;    h Pij x                         | pij_nom  ficrestpij
   double fu;     # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
           1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
   *fa=(*func)(*ax);         1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
   *fb=(*func)(*bx);  
   if (*fb > *fa) {         1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
     SHFT(dum,*ax,*bx,dum)         1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
       SHFT(dum,*fb,*fa,dum)    variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
       }     Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
   *cx=(*bx)+GOLD*(*bx-*ax);     Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
   *fc=(*func)(*cx);  
   while (*fb > *fc) {    forecasting if prevfcast==1 prevforecast call prevalence()
     r=(*bx-*ax)*(*fb-*fc);    health expectancies
     q=(*bx-*cx)*(*fb-*fa);    Variance-covariance of DFLE
     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/    prevalence()
       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r));     movingaverage()
     ulim=(*bx)+GLIMIT*(*cx-*bx);    varevsij() 
     if ((*bx-u)*(u-*cx) > 0.0) {    if popbased==1 varevsij(,popbased)
       fu=(*func)(u);    total life expectancies
     } else if ((*cx-u)*(u-ulim) > 0.0) {    Variance of period (stable) prevalence
       fu=(*func)(u);   end
       if (fu < *fc) {  */
         SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx))  
           SHFT(*fb,*fc,fu,(*func)(u))  
           }  
     } else if ((u-ulim)*(ulim-*cx) >= 0.0) {   
       u=ulim;  #include <math.h>
       fu=(*func)(u);  #include <stdio.h>
     } else {  #include <stdlib.h>
       u=(*cx)+GOLD*(*cx-*bx);  #include <string.h>
       fu=(*func)(u);  
     }  #ifdef _WIN32
     SHFT(*ax,*bx,*cx,u)  #include <io.h>
       SHFT(*fa,*fb,*fc,fu)  #else
       }  #include <unistd.h>
 }  #endif
   
 /*************** linmin ************************/  #include <limits.h>
   #include <sys/types.h>
 int ncom;  #include <sys/stat.h>
 double *pcom,*xicom;  #include <errno.h>
 double (*nrfunc)(double []);  /* extern int errno; */
    
 void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []))  /* #ifdef LINUX */
 {  /* #include <time.h> */
   double brent(double ax, double bx, double cx,  /* #include "timeval.h" */
                double (*f)(double), double tol, double *xmin);  /* #else */
   double f1dim(double x);  /* #include <sys/time.h> */
   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb,  /* #endif */
               double *fc, double (*func)(double));  
   int j;  #include <time.h>
   double xx,xmin,bx,ax;  
   double fx,fb,fa;  #ifdef GSL
    #include <gsl/gsl_errno.h>
   ncom=n;  #include <gsl/gsl_multimin.h>
   pcom=vector(1,n);  #endif
   xicom=vector(1,n);  
   nrfunc=func;  /* #include <libintl.h> */
   for (j=1;j<=n;j++) {  /* #define _(String) gettext (String) */
     pcom[j]=p[j];  
     xicom[j]=xi[j];  #define MAXLINE 1024 /* Was 256. Overflow with 312 with 2 states and 4 covariates. Should be ok */
   }  
   ax=0.0;  #define GNUPLOTPROGRAM "gnuplot"
   xx=1.0;  /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
   mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  #define FILENAMELENGTH 132
   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin);  
 #ifdef DEBUG  #define GLOCK_ERROR_NOPATH              -1      /* empty path */
   printf("retour brent fret=%.12e xmin=%.12e\n",*fret,xmin);  #define GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
 #endif  
   for (j=1;j<=n;j++) {  #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
     xi[j] *= xmin;  #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
     p[j] += xi[j];  
   }  #define NINTERVMAX 8
   free_vector(xicom,1,n);  #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
   free_vector(pcom,1,n);  #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
 }  #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
   #define codtabm(h,k)  1 & (h-1) >> (k-1) ;
 /*************** powell ************************/  #define MAXN 20000
 void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret,  #define YEARM 12. /**< Number of months per year */
             double (*func)(double []))  #define AGESUP 130
 {  #define AGEBASE 40
   void linmin(double p[], double xi[], int n, double *fret,  #define AGEGOMP 10. /**< Minimal age for Gompertz adjustment */
               double (*func)(double []));  #ifdef _WIN32
   int i,ibig,j;  #define DIRSEPARATOR '\\'
   double del,t,*pt,*ptt,*xit;  #define CHARSEPARATOR "\\"
   double fp,fptt;  #define ODIRSEPARATOR '/'
   double *xits;  #else
   pt=vector(1,n);  #define DIRSEPARATOR '/'
   ptt=vector(1,n);  #define CHARSEPARATOR "/"
   xit=vector(1,n);  #define ODIRSEPARATOR '\\'
   xits=vector(1,n);  #endif
   *fret=(*func)(p);  
   for (j=1;j<=n;j++) pt[j]=p[j];  /* $Id$ */
   for (*iter=1;;++(*iter)) {  /* $State$ */
     fp=(*fret);  
     ibig=0;  char version[]="Imach version 0.98nX, August 2014,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121)";
     del=0.0;  char fullversion[]="$Revision$ $Date$"; 
     printf("\nPowell iter=%d -2*LL=%.12f",*iter,*fret);  char strstart[80];
     for (i=1;i<=n;i++)  char optionfilext[10], optionfilefiname[FILENAMELENGTH];
       printf(" %d %.12f",i, p[i]);  int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
     printf("\n");  int nvar=0, nforce=0; /* Number of variables, number of forces */
     for (i=1;i<=n;i++) {  /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
       for (j=1;j<=n;j++) xit[j]=xi[j][i];  int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
       fptt=(*fret);  int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
 #ifdef DEBUG  int cptcovs=0; /**< cptcovs number of simple covariates V2+V1 =2 */
       printf("fret=%lf \n",*fret);  int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
 #endif  int cptcovprodnoage=0; /**< Number of covariate products without age */   
       printf("%d",i);fflush(stdout);  int cptcoveff=0; /* Total number of covariates to vary for printing results */
       linmin(p,xit,n,fret,func);  int cptcov=0; /* Working variable */
       if (fabs(fptt-(*fret)) > del) {  int npar=NPARMAX;
         del=fabs(fptt-(*fret));  int nlstate=2; /* Number of live states */
         ibig=i;  int ndeath=1; /* Number of dead states */
       }  int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
 #ifdef DEBUG  int popbased=0;
       printf("%d %.12e",i,(*fret));  
       for (j=1;j<=n;j++) {  int *wav; /* Number of waves for this individuual 0 is possible */
         xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);  int maxwav=0; /* Maxim number of waves */
         printf(" x(%d)=%.12e",j,xit[j]);  int jmin=0, jmax=0; /* min, max spacing between 2 waves */
       }  int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
       for(j=1;j<=n;j++)  int gipmx=0, gsw=0; /* Global variables on the number of contributions 
         printf(" p=%.12e",p[j]);                     to the likelihood and the sum of weights (done by funcone)*/
       printf("\n");  int mle=1, weightopt=0;
 #endif  int **mw; /* mw[mi][i] is number of the mi wave for this individual */
     }  int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
     if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) {  int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
 #ifdef DEBUG             * wave mi and wave mi+1 is not an exact multiple of stepm. */
       int k[2],l;  double jmean=1; /* Mean space between 2 waves */
       k[0]=1;  double **matprod2(); /* test */
       k[1]=-1;  double **oldm, **newm, **savm; /* Working pointers to matrices */
       printf("Max: %.12e",(*func)(p));  double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
       for (j=1;j<=n;j++)  /*FILE *fic ; */ /* Used in readdata only */
         printf(" %.12e",p[j]);  FILE *ficpar, *ficparo,*ficres, *ficresp, *ficrespl, *ficrespij, *ficrest,*ficresf,*ficrespop;
       printf("\n");  FILE *ficlog, *ficrespow;
       for(l=0;l<=1;l++) {  int globpr=0; /* Global variable for printing or not */
         for (j=1;j<=n;j++) {  double fretone; /* Only one call to likelihood */
           ptt[j]=p[j]+(p[j]-pt[j])*k[l];  long ipmx=0; /* Number of contributions */
           printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);  double sw; /* Sum of weights */
         }  char filerespow[FILENAMELENGTH];
         printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));  char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
       }  FILE *ficresilk;
 #endif  FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
   FILE *ficresprobmorprev;
   FILE *fichtm, *fichtmcov; /* Html File */
       free_vector(xit,1,n);  FILE *ficreseij;
       free_vector(xits,1,n);  char filerese[FILENAMELENGTH];
       free_vector(ptt,1,n);  FILE *ficresstdeij;
       free_vector(pt,1,n);  char fileresstde[FILENAMELENGTH];
       return;  FILE *ficrescveij;
     }  char filerescve[FILENAMELENGTH];
     if (*iter == ITMAX) nrerror("powell exceeding maximum iterations.");  FILE  *ficresvij;
     for (j=1;j<=n;j++) {  char fileresv[FILENAMELENGTH];
       ptt[j]=2.0*p[j]-pt[j];  FILE  *ficresvpl;
       xit[j]=p[j]-pt[j];  char fileresvpl[FILENAMELENGTH];
       pt[j]=p[j];  char title[MAXLINE];
     }  char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH];
     fptt=(*func)(ptt);  char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
     if (fptt < fp) {  char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt);  char command[FILENAMELENGTH];
       if (t < 0.0) {  int  outcmd=0;
         linmin(p,xit,n,fret,func);  
         for (j=1;j<=n;j++) {  char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
           xi[j][ibig]=xi[j][n];  
           xi[j][n]=xit[j];  char filelog[FILENAMELENGTH]; /* Log file */
         }  char filerest[FILENAMELENGTH];
 #ifdef DEBUG  char fileregp[FILENAMELENGTH];
         printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);  char popfile[FILENAMELENGTH];
         for(j=1;j<=n;j++)  
           printf(" %.12e",xit[j]);  char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
         printf("\n");  
 #endif  /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
       }  /* struct timezone tzp; */
     }  /* extern int gettimeofday(); */
   }  struct tm tml, *gmtime(), *localtime();
 }  
   extern time_t time();
 /**** Prevalence limit ****************/  
   struct tm start_time, end_time, curr_time, last_time, forecast_time;
 double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int ij)  time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
 {  struct tm tm;
   /* Computes the prevalence limit in each live state at age x by left multiplying the unit  
      matrix by transitions matrix until convergence is reached */  char strcurr[80], strfor[80];
   
   int i, ii,j,k;  char *endptr;
   double min, max, maxmin, maxmax,sumnew=0.;  long lval;
   double **matprod2();  double dval;
   double **out, cov[NCOVMAX], **pmij();  
   double **newm;  #define NR_END 1
   double agefin, delaymax=50 ; /* Max number of years to converge */  #define FREE_ARG char*
   #define FTOL 1.0e-10
   for (ii=1;ii<=nlstate+ndeath;ii++)  
     for (j=1;j<=nlstate+ndeath;j++){  #define NRANSI 
       oldm[ii][j]=(ii==j ? 1.0 : 0.0);  #define ITMAX 200 
     }  
   #define TOL 2.0e-4 
    cov[1]=1.;  
    #define CGOLD 0.3819660 
  /* Even if hstepm = 1, at least one multiplication by the unit matrix */  #define ZEPS 1.0e-10 
   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){  #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
     newm=savm;  
     /* Covariates have to be included here again */  #define GOLD 1.618034 
      cov[2]=agefin;  #define GLIMIT 100.0 
    #define TINY 1.0e-20 
       for (k=1; k<=cptcovn;k++) {  
         cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]];  static double maxarg1,maxarg2;
         /*printf("ij=%d Tvar[k]=%d nbcode=%d cov=%lf\n",ij, Tvar[k],nbcode[Tvar[k]][codtab[ij][Tvar[k]]],cov[2+k]);*/  #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
       }  #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
       for (k=1; k<=cptcovage;k++)    
         cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];  #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
       for (k=1; k<=cptcovprod;k++)  #define rint(a) floor(a+0.5)
         cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];  
   static double sqrarg;
       /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/  #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
       /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/  #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
   int agegomp= AGEGOMP;
     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);  
   int imx; 
     savm=oldm;  int stepm=1;
     oldm=newm;  /* Stepm, step in month: minimum step interpolation*/
     maxmax=0.;  
     for(j=1;j<=nlstate;j++){  int estepm;
       min=1.;  /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
       max=0.;  
       for(i=1; i<=nlstate; i++) {  int m,nb;
         sumnew=0;  long *num;
         for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];  int firstpass=0, lastpass=4,*cod, *ncodemax, *Tage,*cens;
         prlim[i][j]= newm[i][j]/(1-sumnew);  double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
         max=FMAX(max,prlim[i][j]);  double **pmmij, ***probs;
         min=FMIN(min,prlim[i][j]);  double *ageexmed,*agecens;
       }  double dateintmean=0;
       maxmin=max-min;  
       maxmax=FMAX(maxmax,maxmin);  double *weight;
     }  int **s; /* Status */
     if(maxmax < ftolpl){  double *agedc;
       return prlim;  double  **covar; /**< covar[j,i], value of jth covariate for individual i,
     }                    * covar=matrix(0,NCOVMAX,1,n); 
   }                    * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2]; */
 }  double  idx; 
   int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
 /*************** transition probabilities **********/  int *Ndum; /** Freq of modality (tricode */
   int **codtab; /**< codtab=imatrix(1,100,1,10); */
 double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )  int **Tvard, *Tprod, cptcovprod, *Tvaraff;
 {  double *lsurv, *lpop, *tpop;
   double s1, s2;  
   /*double t34;*/  double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
   int i,j,j1, nc, ii, jj;  double ftolhess; /**< Tolerance for computing hessian */
   
     for(i=1; i<= nlstate; i++){  /**************** split *************************/
     for(j=1; j<i;j++){  static  int split( char *path, char *dirc, char *name, char *ext, char *finame )
       for (nc=1, s2=0.;nc <=ncovmodel; nc++){  {
         /*s2 += param[i][j][nc]*cov[nc];*/    /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
         s2 += x[(i-1)*nlstate*ncovmodel+(j-1)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];       the name of the file (name), its extension only (ext) and its first part of the name (finame)
         /*printf("Int j<i s1=%.17e, s2=%.17e\n",s1,s2);*/    */ 
       }    char  *ss;                            /* pointer */
       ps[i][j]=s2;    int   l1, l2;                         /* length counters */
       /*printf("s1=%.17e, s2=%.17e\n",s1,s2);*/  
     }    l1 = strlen(path );                   /* length of path */
     for(j=i+1; j<=nlstate+ndeath;j++){    if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
       for (nc=1, s2=0.;nc <=ncovmodel; nc++){    ss= strrchr( path, DIRSEPARATOR );            /* find last / */
         s2 += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];    if ( ss == NULL ) {                   /* no directory, so determine current directory */
         /*printf("Int j>i s1=%.17e, s2=%.17e %lx %lx\n",s1,s2,s1,s2);*/      strcpy( name, path );               /* we got the fullname name because no directory */
       }      /*if(strrchr(path, ODIRSEPARATOR )==NULL)
       ps[i][j]=s2;        printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
     }      /* get current working directory */
   }      /*    extern  char* getcwd ( char *buf , int len);*/
   for(i=1; i<= nlstate; i++){      if ( getcwd( dirc, FILENAME_MAX ) == NULL ) {
      s1=0;        return( GLOCK_ERROR_GETCWD );
     for(j=1; j<i; j++)      }
       s1+=exp(ps[i][j]);      /* got dirc from getcwd*/
     for(j=i+1; j<=nlstate+ndeath; j++)      printf(" DIRC = %s \n",dirc);
       s1+=exp(ps[i][j]);    } else {                              /* strip direcotry from path */
     ps[i][i]=1./(s1+1.);      ss++;                               /* after this, the filename */
     for(j=1; j<i; j++)      l2 = strlen( ss );                  /* length of filename */
       ps[i][j]= exp(ps[i][j])*ps[i][i];      if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
     for(j=i+1; j<=nlstate+ndeath; j++)      strcpy( name, ss );         /* save file name */
       ps[i][j]= exp(ps[i][j])*ps[i][i];      strncpy( dirc, path, l1 - l2 );     /* now the directory */
     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */      dirc[l1-l2] = 0;                    /* add zero */
   } /* end i */      printf(" DIRC2 = %s \n",dirc);
     }
   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){    /* We add a separator at the end of dirc if not exists */
     for(jj=1; jj<= nlstate+ndeath; jj++){    l1 = strlen( dirc );                  /* length of directory */
       ps[ii][jj]=0;    if( dirc[l1-1] != DIRSEPARATOR ){
       ps[ii][ii]=1;      dirc[l1] =  DIRSEPARATOR;
     }      dirc[l1+1] = 0; 
   }      printf(" DIRC3 = %s \n",dirc);
     }
   /*   for(ii=1; ii<= nlstate+ndeath; ii++){    ss = strrchr( name, '.' );            /* find last / */
     for(jj=1; jj<= nlstate+ndeath; jj++){    if (ss >0){
      printf("%lf ",ps[ii][jj]);      ss++;
    }      strcpy(ext,ss);                     /* save extension */
     printf("\n ");      l1= strlen( name);
     }      l2= strlen(ss)+1;
     printf("\n ");printf("%lf ",cov[2]);*/      strncpy( finame, name, l1-l2);
 /*      finame[l1-l2]= 0;
   for(i=1; i<= npar; i++) printf("%f ",x[i]);    }
   goto end;*/  
     return ps;    return( 0 );                          /* we're done */
 }  }
   
 /**************** Product of 2 matrices ******************/  
   /******************************************/
 double **matprod2(double **out, double **in,long nrl, long nrh, long ncl, long nch, long ncolol, long ncoloh, double **b)  
 {  void replace_back_to_slash(char *s, char*t)
   /* Computes the matric product of in(1,nrh-nrl+1)(1,nch-ncl+1) times  {
      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */    int i;
   /* in, b, out are matrice of pointers which should have been initialized    int lg=0;
      before: only the contents of out is modified. The function returns    i=0;
      a pointer to pointers identical to out */    lg=strlen(t);
   long i, j, k;    for(i=0; i<= lg; i++) {
   for(i=nrl; i<= nrh; i++)      (s[i] = t[i]);
     for(k=ncolol; k<=ncoloh; k++)      if (t[i]== '\\') s[i]='/';
       for(j=ncl,out[i][k]=0.; j<=nch; j++)    }
         out[i][k] +=in[i][j]*b[j][k];  }
   
   return out;  char *trimbb(char *out, char *in)
 }  { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
     char *s;
     s=out;
 /************* Higher Matrix Product ***************/    while (*in != '\0'){
       while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
 double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij )        in++;
 {      }
   /* Computes the transition matrix starting at age 'age' over 'nhstepm*hstepm*stepm' month      *out++ = *in++;
      duration (i.e. until    }
      age (in years)  age+nhstepm*stepm/12) by multiplying nhstepm*hstepm matrices.    *out='\0';
      Output is stored in matrix po[i][j][h] for h every 'hstepm' step    return s;
      (typically every 2 years instead of every month which is too big).  }
      Model is determined by parameters x and covariates have to be  
      included manually here.  char *cutl(char *blocc, char *alocc, char *in, char occ)
   {
      */    /* cuts string in into blocc and alocc where blocc ends before first occurence of char 'occ' 
        and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
   int i, j, d, h, k;       gives blocc="abcdef2ghi" and alocc="j".
   double **out, cov[NCOVMAX];       If occ is not found blocc is null and alocc is equal to in. Returns blocc
   double **newm;    */
     char *s, *t;
   /* Hstepm could be zero and should return the unit matrix */    t=in;s=in;
   for (i=1;i<=nlstate+ndeath;i++)    while ((*in != occ) && (*in != '\0')){
     for (j=1;j<=nlstate+ndeath;j++){      *alocc++ = *in++;
       oldm[i][j]=(i==j ? 1.0 : 0.0);    }
       po[i][j][0]=(i==j ? 1.0 : 0.0);    if( *in == occ){
     }      *(alocc)='\0';
   /* Even if hstepm = 1, at least one multiplication by the unit matrix */      s=++in;
   for(h=1; h <=nhstepm; h++){    }
     for(d=1; d <=hstepm; d++){   
       newm=savm;    if (s == t) {/* occ not found */
       /* Covariates have to be included here again */      *(alocc-(in-s))='\0';
       cov[1]=1.;      in=s;
       cov[2]=age+((h-1)*hstepm + (d-1))*stepm/YEARM;    }
       for (k=1; k<=cptcovn;k++) cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]];    while ( *in != '\0'){
 for (k=1; k<=cptcovage;k++)      *blocc++ = *in++;
         cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];    }
    for (k=1; k<=cptcovprod;k++)  
         cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];    *blocc='\0';
     return t;
   }
       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/  char *cutv(char *blocc, char *alocc, char *in, char occ)
       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/  {
       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,    /* cuts string in into blocc and alocc where blocc ends before last occurence of char 'occ' 
                    pmij(pmmij,cov,ncovmodel,x,nlstate));       and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
       savm=oldm;       gives blocc="abcdef2ghi" and alocc="j".
       oldm=newm;       If occ is not found blocc is null and alocc is equal to in. Returns alocc
     }    */
     for(i=1; i<=nlstate+ndeath; i++)    char *s, *t;
       for(j=1;j<=nlstate+ndeath;j++) {    t=in;s=in;
         po[i][j][h]=newm[i][j];    while (*in != '\0'){
         /*printf("i=%d j=%d h=%d po[i][j][h]=%f ",i,j,h,po[i][j][h]);      while( *in == occ){
          */        *blocc++ = *in++;
       }        s=in;
   } /* end h */      }
   return po;      *blocc++ = *in++;
 }    }
     if (s == t) /* occ not found */
       *(blocc-(in-s))='\0';
 /*************** log-likelihood *************/    else
 double func( double *x)      *(blocc-(in-s)-1)='\0';
 {    in=s;
   int i, ii, j, k, mi, d, kk;    while ( *in != '\0'){
   double l, ll[NLSTATEMAX], cov[NCOVMAX];      *alocc++ = *in++;
   double **out;    }
   double sw; /* Sum of weights */  
   double lli; /* Individual log likelihood */    *alocc='\0';
   long ipmx;    return s;
   /*extern weight */  }
   /* We are differentiating ll according to initial status */  
   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/  int nbocc(char *s, char occ)
   /*for(i=1;i<imx;i++)  {
     printf(" %d\n",s[4][i]);    int i,j=0;
   */    int lg=20;
   cov[1]=1.;    i=0;
     lg=strlen(s);
   for(k=1; k<=nlstate; k++) ll[k]=0.;    for(i=0; i<= lg; i++) {
   for (i=1,ipmx=0, sw=0.; i<=imx; i++){    if  (s[i] == occ ) j++;
     for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];    }
     for(mi=1; mi<= wav[i]-1; mi++){    return j;
       for (ii=1;ii<=nlstate+ndeath;ii++)  }
         for (j=1;j<=nlstate+ndeath;j++) oldm[ii][j]=(ii==j ? 1.0 : 0.0);  
       for(d=0; d<dh[mi][i]; d++){  /* void cutv(char *u,char *v, char*t, char occ) */
         newm=savm;  /* { */
         cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;  /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
         for (kk=1; kk<=cptcovage;kk++) {  /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
           cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];  /*      gives u="abcdef2ghi" and v="j" *\/ */
         }  /*   int i,lg,j,p=0; */
          /*   i=0; */
         out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,  /*   lg=strlen(t); */
                      1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));  /*   for(j=0; j<=lg-1; j++) { */
         savm=oldm;  /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
         oldm=newm;  /*   } */
          
          /*   for(j=0; j<p; j++) { */
       } /* end mult */  /*     (u[j] = t[j]); */
        /*   } */
       lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);  /*      u[p]='\0'; */
       /* printf(" %f ",out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/  
       ipmx +=1;  /*    for(j=0; j<= lg; j++) { */
       sw += weight[i];  /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;  /*   } */
     } /* end of wave */  /* } */
   } /* end of individual */  
   #ifdef _WIN32
   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];  char * strsep(char **pp, const char *delim)
   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */  {
   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */    char *p, *q;
   return -l;           
 }    if ((p = *pp) == NULL)
       return 0;
     if ((q = strpbrk (p, delim)) != NULL)
 /*********** Maximum Likelihood Estimation ***************/    {
       *pp = q + 1;
 void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))      *q = '\0';
 {    }
   int i,j, iter;    else
   double **xi,*delti;      *pp = 0;
   double fret;    return p;
   xi=matrix(1,npar,1,npar);  }
   for (i=1;i<=npar;i++)  #endif
     for (j=1;j<=npar;j++)  
       xi[i][j]=(i==j ? 1.0 : 0.0);  /********************** nrerror ********************/
   printf("Powell\n");  
   powell(p,xi,npar,ftol,&iter,&fret,func);  void nrerror(char error_text[])
   {
    printf("\n#Number of iterations = %d, -2 Log likelihood = %.12f\n",iter,func(p));    fprintf(stderr,"ERREUR ...\n");
   fprintf(ficres,"#Number of iterations = %d, -2 Log likelihood = %.12f ",iter,func(p));    fprintf(stderr,"%s\n",error_text);
     exit(EXIT_FAILURE);
 }  }
   /*********************** vector *******************/
 /**** Computes Hessian and covariance matrix ***/  double *vector(int nl, int nh)
 void hesscov(double **matcov, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))  {
 {    double *v;
   double  **a,**y,*x,pd;    v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
   double **hess;    if (!v) nrerror("allocation failure in vector");
   int i, j,jk;    return v-nl+NR_END;
   int *indx;  }
   
   double hessii(double p[], double delta, int theta, double delti[]);  /************************ free vector ******************/
   double hessij(double p[], double delti[], int i, int j);  void free_vector(double*v, int nl, int nh)
   void lubksb(double **a, int npar, int *indx, double b[]) ;  {
   void ludcmp(double **a, int npar, int *indx, double *d) ;    free((FREE_ARG)(v+nl-NR_END));
   }
   
   hess=matrix(1,npar,1,npar);  /************************ivector *******************************/
   int *ivector(long nl,long nh)
   printf("\nCalculation of the hessian matrix. Wait...\n");  {
   for (i=1;i<=npar;i++){    int *v;
     printf("%d",i);fflush(stdout);    v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
     hess[i][i]=hessii(p,ftolhess,i,delti);    if (!v) nrerror("allocation failure in ivector");
     /*printf(" %f ",p[i]);*/    return v-nl+NR_END;
   }  }
   
   for (i=1;i<=npar;i++) {  /******************free ivector **************************/
     for (j=1;j<=npar;j++)  {  void free_ivector(int *v, long nl, long nh)
       if (j>i) {  {
         printf(".%d%d",i,j);fflush(stdout);    free((FREE_ARG)(v+nl-NR_END));
         hess[i][j]=hessij(p,delti,i,j);  }
         hess[j][i]=hess[i][j];  
       }  /************************lvector *******************************/
     }  long *lvector(long nl,long nh)
   }  {
   printf("\n");    long *v;
     v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");    if (!v) nrerror("allocation failure in ivector");
      return v-nl+NR_END;
   a=matrix(1,npar,1,npar);  }
   y=matrix(1,npar,1,npar);  
   x=vector(1,npar);  /******************free lvector **************************/
   indx=ivector(1,npar);  void free_lvector(long *v, long nl, long nh)
   for (i=1;i<=npar;i++)  {
     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];    free((FREE_ARG)(v+nl-NR_END));
   ludcmp(a,npar,indx,&pd);  }
   
   for (j=1;j<=npar;j++) {  /******************* imatrix *******************************/
     for (i=1;i<=npar;i++) x[i]=0;  int **imatrix(long nrl, long nrh, long ncl, long nch) 
     x[j]=1;       /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
     lubksb(a,npar,indx,x);  { 
     for (i=1;i<=npar;i++){    long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
       matcov[i][j]=x[i];    int **m; 
     }    
   }    /* allocate pointers to rows */ 
     m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
   printf("\n#Hessian matrix#\n");    if (!m) nrerror("allocation failure 1 in matrix()"); 
   for (i=1;i<=npar;i++) {    m += NR_END; 
     for (j=1;j<=npar;j++) {    m -= nrl; 
       printf("%.3e ",hess[i][j]);    
     }    
     printf("\n");    /* allocate rows and set pointers to them */ 
   }    m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
     if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
   /* Recompute Inverse */    m[nrl] += NR_END; 
   for (i=1;i<=npar;i++)    m[nrl] -= ncl; 
     for (j=1;j<=npar;j++) a[i][j]=matcov[i][j];    
   ludcmp(a,npar,indx,&pd);    for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
     
   /*  printf("\n#Hessian matrix recomputed#\n");    /* return pointer to array of pointers to rows */ 
     return m; 
   for (j=1;j<=npar;j++) {  } 
     for (i=1;i<=npar;i++) x[i]=0;  
     x[j]=1;  /****************** free_imatrix *************************/
     lubksb(a,npar,indx,x);  void free_imatrix(m,nrl,nrh,ncl,nch)
     for (i=1;i<=npar;i++){        int **m;
       y[i][j]=x[i];        long nch,ncl,nrh,nrl; 
       printf("%.3e ",y[i][j]);       /* free an int matrix allocated by imatrix() */ 
     }  { 
     printf("\n");    free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
   }    free((FREE_ARG) (m+nrl-NR_END)); 
   */  } 
   
   free_matrix(a,1,npar,1,npar);  /******************* matrix *******************************/
   free_matrix(y,1,npar,1,npar);  double **matrix(long nrl, long nrh, long ncl, long nch)
   free_vector(x,1,npar);  {
   free_ivector(indx,1,npar);    long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
   free_matrix(hess,1,npar,1,npar);    double **m;
   
     m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
 }    if (!m) nrerror("allocation failure 1 in matrix()");
     m += NR_END;
 /*************** hessian matrix ****************/    m -= nrl;
 double hessii( double x[], double delta, int theta, double delti[])  
 {    m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
   int i;    if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
   int l=1, lmax=20;    m[nrl] += NR_END;
   double k1,k2;    m[nrl] -= ncl;
   double p2[NPARMAX+1];  
   double res;    for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
   double delt, delts, nkhi=10.,nkhif=1., khi=1.e-4;    return m;
   double fx;    /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
   int k=0,kmax=10;  m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
   double l1;  that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
      */
   fx=func(x);  }
   for (i=1;i<=npar;i++) p2[i]=x[i];  
   for(l=0 ; l <=lmax; l++){  /*************************free matrix ************************/
     l1=pow(10,l);  void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
     delts=delt;  {
     for(k=1 ; k <kmax; k=k+1){    free((FREE_ARG)(m[nrl]+ncl-NR_END));
       delt = delta*(l1*k);    free((FREE_ARG)(m+nrl-NR_END));
       p2[theta]=x[theta] +delt;  }
       k1=func(p2)-fx;  
       p2[theta]=x[theta]-delt;  /******************* ma3x *******************************/
       k2=func(p2)-fx;  double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
       /*res= (k1-2.0*fx+k2)/delt/delt; */  {
       res= (k1+k2)/delt/delt/2.; /* Divided by because L and not 2*L */    long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
          double ***m;
 #ifdef DEBUG  
       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);    m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
 #endif    if (!m) nrerror("allocation failure 1 in matrix()");
       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */    m += NR_END;
       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){    m -= nrl;
         k=kmax;  
       }    m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */    if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
         k=kmax; l=lmax*10.;    m[nrl] += NR_END;
       }    m[nrl] -= ncl;
       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  
         delts=delt;    for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
       }  
     }    m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
   }    if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
   delti[theta]=delts;    m[nrl][ncl] += NR_END;
   return res;    m[nrl][ncl] -= nll;
      for (j=ncl+1; j<=nch; j++) 
 }      m[nrl][j]=m[nrl][j-1]+nlay;
     
 double hessij( double x[], double delti[], int thetai,int thetaj)    for (i=nrl+1; i<=nrh; i++) {
 {      m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
   int i;      for (j=ncl+1; j<=nch; j++) 
   int l=1, l1, lmax=20;        m[i][j]=m[i][j-1]+nlay;
   double k1,k2,k3,k4,res,fx;    }
   double p2[NPARMAX+1];    return m; 
   int k;    /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
              &(m[i][j][k]) <=> *((*(m+i) + j)+k)
   fx=func(x);    */
   for (k=1; k<=2; k++) {  }
     for (i=1;i<=npar;i++) p2[i]=x[i];  
     p2[thetai]=x[thetai]+delti[thetai]/k;  /*************************free ma3x ************************/
     p2[thetaj]=x[thetaj]+delti[thetaj]/k;  void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
     k1=func(p2)-fx;  {
      free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
     p2[thetai]=x[thetai]+delti[thetai]/k;    free((FREE_ARG)(m[nrl]+ncl-NR_END));
     p2[thetaj]=x[thetaj]-delti[thetaj]/k;    free((FREE_ARG)(m+nrl-NR_END));
     k2=func(p2)-fx;  }
    
     p2[thetai]=x[thetai]-delti[thetai]/k;  /*************** function subdirf ***********/
     p2[thetaj]=x[thetaj]+delti[thetaj]/k;  char *subdirf(char fileres[])
     k3=func(p2)-fx;  {
      /* Caution optionfilefiname is hidden */
     p2[thetai]=x[thetai]-delti[thetai]/k;    strcpy(tmpout,optionfilefiname);
     p2[thetaj]=x[thetaj]-delti[thetaj]/k;    strcat(tmpout,"/"); /* Add to the right */
     k4=func(p2)-fx;    strcat(tmpout,fileres);
     res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /* Because of L not 2*L */    return tmpout;
 #ifdef DEBUG  }
     printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);  
 #endif  /*************** function subdirf2 ***********/
   }  char *subdirf2(char fileres[], char *preop)
   return res;  {
 }    
     /* Caution optionfilefiname is hidden */
 /************** Inverse of matrix **************/    strcpy(tmpout,optionfilefiname);
 void ludcmp(double **a, int n, int *indx, double *d)    strcat(tmpout,"/");
 {    strcat(tmpout,preop);
   int i,imax,j,k;    strcat(tmpout,fileres);
   double big,dum,sum,temp;    return tmpout;
   double *vv;  }
    
   vv=vector(1,n);  /*************** function subdirf3 ***********/
   *d=1.0;  char *subdirf3(char fileres[], char *preop, char *preop2)
   for (i=1;i<=n;i++) {  {
     big=0.0;    
     for (j=1;j<=n;j++)    /* Caution optionfilefiname is hidden */
       if ((temp=fabs(a[i][j])) > big) big=temp;    strcpy(tmpout,optionfilefiname);
     if (big == 0.0) nrerror("Singular matrix in routine ludcmp");    strcat(tmpout,"/");
     vv[i]=1.0/big;    strcat(tmpout,preop);
   }    strcat(tmpout,preop2);
   for (j=1;j<=n;j++) {    strcat(tmpout,fileres);
     for (i=1;i<j;i++) {    return tmpout;
       sum=a[i][j];  }
       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j];  
       a[i][j]=sum;  /***************** f1dim *************************/
     }  extern int ncom; 
     big=0.0;  extern double *pcom,*xicom;
     for (i=j;i<=n;i++) {  extern double (*nrfunc)(double []); 
       sum=a[i][j];   
       for (k=1;k<j;k++)  double f1dim(double x) 
         sum -= a[i][k]*a[k][j];  { 
       a[i][j]=sum;    int j; 
       if ( (dum=vv[i]*fabs(sum)) >= big) {    double f;
         big=dum;    double *xt; 
         imax=i;   
       }    xt=vector(1,ncom); 
     }    for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
     if (j != imax) {    f=(*nrfunc)(xt); 
       for (k=1;k<=n;k++) {    free_vector(xt,1,ncom); 
         dum=a[imax][k];    return f; 
         a[imax][k]=a[j][k];  } 
         a[j][k]=dum;  
       }  /*****************brent *************************/
       *d = -(*d);  double brent(double ax, double bx, double cx, double (*f)(double), double tol,  double *xmin) 
       vv[imax]=vv[j];  { 
     }    int iter; 
     indx[j]=imax;    double a,b,d,etemp;
     if (a[j][j] == 0.0) a[j][j]=TINY;    double fu=0,fv,fw,fx;
     if (j != n) {    double ftemp;
       dum=1.0/(a[j][j]);    double p,q,r,tol1,tol2,u,v,w,x,xm; 
       for (i=j+1;i<=n;i++) a[i][j] *= dum;    double e=0.0; 
     }   
   }    a=(ax < cx ? ax : cx); 
   free_vector(vv,1,n);  /* Doesn't work */    b=(ax > cx ? ax : cx); 
 ;    x=w=v=bx; 
 }    fw=fv=fx=(*f)(x); 
     for (iter=1;iter<=ITMAX;iter++) { 
 void lubksb(double **a, int n, int *indx, double b[])      xm=0.5*(a+b); 
 {      tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
   int i,ii=0,ip,j;      /*          if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
   double sum;      printf(".");fflush(stdout);
        fprintf(ficlog,".");fflush(ficlog);
   for (i=1;i<=n;i++) {  #ifdef DEBUG
     ip=indx[i];      printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
     sum=b[ip];      fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
     b[ip]=b[i];      /*          if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
     if (ii)  #endif
       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j];      if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
     else if (sum) ii=i;        *xmin=x; 
     b[i]=sum;        return fx; 
   }      } 
   for (i=n;i>=1;i--) {      ftemp=fu;
     sum=b[i];      if (fabs(e) > tol1) { 
     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j];        r=(x-w)*(fx-fv); 
     b[i]=sum/a[i][i];        q=(x-v)*(fx-fw); 
   }        p=(x-v)*q-(x-w)*r; 
 }        q=2.0*(q-r); 
         if (q > 0.0) p = -p; 
 /************ Frequencies ********************/        q=fabs(q); 
 void  freqsummary(char fileres[], int agemin, int agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax)        etemp=e; 
 {  /* Some frequencies */        e=d; 
          if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
   int i, m, jk, k1, i1, j1, bool, z1,z2,j;          d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
   double ***freq; /* Frequencies */        else { 
   double *pp;          d=p/q; 
   double pos;          u=x+d; 
   FILE *ficresp;          if (u-a < tol2 || b-u < tol2) 
   char fileresp[FILENAMELENGTH];            d=SIGN(tol1,xm-x); 
         } 
   pp=vector(1,nlstate);      } else { 
         d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
   strcpy(fileresp,"p");      } 
   strcat(fileresp,fileres);      u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
   if((ficresp=fopen(fileresp,"w"))==NULL) {      fu=(*f)(u); 
     printf("Problem with prevalence resultfile: %s\n", fileresp);      if (fu <= fx) { 
     exit(0);        if (u >= x) a=x; else b=x; 
   }        SHFT(v,w,x,u) 
   freq= ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,agemin,agemax+3);          SHFT(fv,fw,fx,fu) 
   j1=0;          } else { 
             if (u < x) a=u; else b=u; 
   j=cptcoveff;            if (fu <= fw || w == x) { 
   if (cptcovn<1) {j=1;ncodemax[1]=1;}              v=w; 
               w=u; 
   for(k1=1; k1<=j;k1++){              fv=fw; 
    for(i1=1; i1<=ncodemax[k1];i1++){              fw=fu; 
        j1++;            } else if (fu <= fv || v == x || v == w) { 
        /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);              v=u; 
          scanf("%d", i);*/              fv=fu; 
         for (i=-1; i<=nlstate+ndeath; i++)              } 
          for (jk=-1; jk<=nlstate+ndeath; jk++)            } 
            for(m=agemin; m <= agemax+3; m++)    } 
              freq[i][jk][m]=0;    nrerror("Too many iterations in brent"); 
            *xmin=x; 
        for (i=1; i<=imx; i++) {    return fx; 
          bool=1;  } 
          if  (cptcovn>0) {  
            for (z1=1; z1<=cptcoveff; z1++)  /****************** mnbrak ***********************/
              if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtab[j1][z1]])  
                bool=0;  void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
          }              double (*func)(double)) 
           if (bool==1) {  { 
            for(m=firstpass; m<=lastpass-1; m++){    double ulim,u,r,q, dum;
              if(agev[m][i]==0) agev[m][i]=agemax+1;    double fu; 
              if(agev[m][i]==1) agev[m][i]=agemax+2;   
              freq[s[m][i]][s[m+1][i]][(int)agev[m][i]] += weight[i];    *fa=(*func)(*ax); 
              freq[s[m][i]][s[m+1][i]][(int) agemax+3] += weight[i];    *fb=(*func)(*bx); 
            }    if (*fb > *fa) { 
          }      SHFT(dum,*ax,*bx,dum) 
        }        SHFT(dum,*fb,*fa,dum) 
         if  (cptcovn>0) {        } 
          fprintf(ficresp, "\n#********** Variable ");    *cx=(*bx)+GOLD*(*bx-*ax); 
          for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);    *fc=(*func)(*cx); 
        fprintf(ficresp, "**********\n#");    while (*fb > *fc) { 
         }      r=(*bx-*ax)*(*fb-*fc); 
        for(i=1; i<=nlstate;i++)      q=(*bx-*cx)*(*fb-*fa); 
          fprintf(ficresp, " Age Prev(%d) N(%d) N",i,i);      u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
        fprintf(ficresp, "\n");        (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); 
              ulim=(*bx)+GLIMIT*(*cx-*bx); 
   for(i=(int)agemin; i <= (int)agemax+3; i++){      if ((*bx-u)*(u-*cx) > 0.0) { 
     if(i==(int)agemax+3)        fu=(*func)(u); 
       printf("Total");      } else if ((*cx-u)*(u-ulim) > 0.0) { 
     else        fu=(*func)(u); 
       printf("Age %d", i);        if (fu < *fc) { 
     for(jk=1; jk <=nlstate ; jk++){          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
       for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)            SHFT(*fb,*fc,fu,(*func)(u)) 
         pp[jk] += freq[jk][m][i];            } 
     }      } else if ((u-ulim)*(ulim-*cx) >= 0.0) { 
     for(jk=1; jk <=nlstate ; jk++){        u=ulim; 
       for(m=-1, pos=0; m <=0 ; m++)        fu=(*func)(u); 
         pos += freq[jk][m][i];      } else { 
       if(pp[jk]>=1.e-10)        u=(*cx)+GOLD*(*cx-*bx); 
         printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);        fu=(*func)(u); 
       else      } 
         printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);      SHFT(*ax,*bx,*cx,u) 
     }        SHFT(*fa,*fb,*fc,fu) 
     for(jk=1; jk <=nlstate ; jk++){        } 
       for(m=1, pp[jk]=0; m <=nlstate+ndeath; m++)  } 
         pp[jk] += freq[jk][m][i];  
     }  /*************** linmin ************************/
     for(jk=1,pos=0; jk <=nlstate ; jk++)  
       pos += pp[jk];  int ncom; 
     for(jk=1; jk <=nlstate ; jk++){  double *pcom,*xicom;
       if(pos>=1.e-5)  double (*nrfunc)(double []); 
         printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);   
       else  void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
         printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);  { 
       if( i <= (int) agemax){    double brent(double ax, double bx, double cx, 
         if(pos>=1.e-5)                 double (*f)(double), double tol, double *xmin); 
           fprintf(ficresp," %d %.5f %.0f %.0f",i,pp[jk]/pos, pp[jk],pos);    double f1dim(double x); 
       else    void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
           fprintf(ficresp," %d NaNq %.0f %.0f",i,pp[jk],pos);                double *fc, double (*func)(double)); 
       }    int j; 
     }    double xx,xmin,bx,ax; 
     for(jk=-1; jk <=nlstate+ndeath; jk++)    double fx,fb,fa;
       for(m=-1; m <=nlstate+ndeath; m++)   
         if(freq[jk][m][i] !=0 ) printf(" %d%d=%.0f",jk,m,freq[jk][m][i]);    ncom=n; 
     if(i <= (int) agemax)    pcom=vector(1,n); 
       fprintf(ficresp,"\n");    xicom=vector(1,n); 
     printf("\n");    nrfunc=func; 
     }    for (j=1;j<=n;j++) { 
     }      pcom[j]=p[j]; 
  }      xicom[j]=xi[j]; 
      } 
   fclose(ficresp);    ax=0.0; 
   free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath,(int) agemin,(int) agemax+3);    xx=1.0; 
   free_vector(pp,1,nlstate);    mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim); 
     *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); 
 }  /* End of Freq */  #ifdef DEBUG
     printf("retour brent fret=%.12e xmin=%.12e\n",*fret,xmin);
 /************* Waves Concatenation ***************/    fprintf(ficlog,"retour brent fret=%.12e xmin=%.12e\n",*fret,xmin);
   #endif
 void  concatwav(int wav[], int **dh, int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)    for (j=1;j<=n;j++) { 
 {      xi[j] *= xmin; 
   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.      p[j] += xi[j]; 
      Death is a valid wave (if date is known).    } 
      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i    free_vector(xicom,1,n); 
      dh[m][i] of dh[mw[mi][i][i] is the delay between two effective waves m=mw[mi][i]    free_vector(pcom,1,n); 
      and mw[mi+1][i]. dh depends on stepm.  } 
      */  
   char *asc_diff_time(long time_sec, char ascdiff[])
   int i, mi, m;  {
   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;    long sec_left, days, hours, minutes;
      double sum=0., jmean=0.;*/    days = (time_sec) / (60*60*24);
     sec_left = (time_sec) % (60*60*24);
 int j, k=0,jk, ju, jl;    hours = (sec_left) / (60*60) ;
      double sum=0.;    sec_left = (sec_left) %(60*60);
 jmin=1e+5;    minutes = (sec_left) /60;
  jmax=-1;    sec_left = (sec_left) % (60);
 jmean=0.;    sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
   for(i=1; i<=imx; i++){    return ascdiff;
     mi=0;  }
     m=firstpass;  
     while(s[m][i] <= nlstate){  /*************** powell ************************/
       if(s[m][i]>=1)  void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
         mw[++mi][i]=m;              double (*func)(double [])) 
       if(m >=lastpass)  { 
         break;    void linmin(double p[], double xi[], int n, double *fret, 
       else                double (*func)(double [])); 
         m++;    int i,ibig,j; 
     }/* end while */    double del,t,*pt,*ptt,*xit;
     if (s[m][i] > nlstate){    double fp,fptt;
       mi++;     /* Death is another wave */    double *xits;
       /* if(mi==0)  never been interviewed correctly before death */    int niterf, itmp;
          /* Only death is a correct wave */  
       mw[mi][i]=m;    pt=vector(1,n); 
     }    ptt=vector(1,n); 
     xit=vector(1,n); 
     wav[i]=mi;    xits=vector(1,n); 
     if(mi==0)    *fret=(*func)(p); 
       printf("Warning, no any valid information for:%d line=%d\n",num[i],i);    for (j=1;j<=n;j++) pt[j]=p[j]; 
   }      rcurr_time = time(NULL);  
     for (*iter=1;;++(*iter)) { 
   for(i=1; i<=imx; i++){      fp=(*fret); 
     for(mi=1; mi<wav[i];mi++){      ibig=0; 
       if (stepm <=0)      del=0.0; 
         dh[mi][i]=1;      rlast_time=rcurr_time;
       else{      /* (void) gettimeofday(&curr_time,&tzp); */
         if (s[mw[mi+1][i]][i] > nlstate) {      rcurr_time = time(NULL);  
           j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12);      curr_time = *localtime(&rcurr_time);
           /*if ((j<0) || (j>28)) printf("j=%d num=%d ",j,i);*/      printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
           if(j==0) j=1;  /* Survives at least one month after exam */      fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
           k=k+1;  /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
           if (j >= jmax) jmax=j;     for (i=1;i<=n;i++) {
           else if (j <= jmin)jmin=j;        printf(" %d %.12f",i, p[i]);
           sum=sum+j;        fprintf(ficlog," %d %.12lf",i, p[i]);
         }        fprintf(ficrespow," %.12lf", p[i]);
         else{      }
           j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));      printf("\n");
           /*if ((j<0) || (j>28)) printf("j=%d num=%d ",j,i);*/      fprintf(ficlog,"\n");
           k=k+1;      fprintf(ficrespow,"\n");fflush(ficrespow);
           if (j >= jmax) jmax=j;      if(*iter <=3){
           else if (j <= jmin)jmin=j;        tml = *localtime(&rcurr_time);
           sum=sum+j;        strcpy(strcurr,asctime(&tml));
         }  /*       asctime_r(&tm,strcurr); */
         jk= j/stepm;        rforecast_time=rcurr_time; 
         jl= j -jk*stepm;        itmp = strlen(strcurr);
         ju= j -(jk+1)*stepm;        if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
         if(jl <= -ju)          strcurr[itmp-1]='\0';
           dh[mi][i]=jk;        printf("\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
         else        fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
           dh[mi][i]=jk+1;        for(niterf=10;niterf<=30;niterf+=10){
         if(dh[mi][i]==0)          rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
           dh[mi][i]=1; /* At least one step */          forecast_time = *localtime(&rforecast_time);
       }  /*      asctime_r(&tmf,strfor); */
     }          strcpy(strfor,asctime(&forecast_time));
   }          itmp = strlen(strfor);
   jmean=sum/k;          if(strfor[itmp-1]=='\n')
   printf("Delay (in months) between two waves Min=%d Max=%d Mean=%f\n\n ",jmin, jmax,jmean);          strfor[itmp-1]='\0';
 }          printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
 /*********** Tricode ****************************/          fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
 void tricode(int *Tvar, int **nbcode, int imx)        }
 {      }
   int Ndum[20],ij=1, k, j, i;      for (i=1;i<=n;i++) { 
   int cptcode=0;        for (j=1;j<=n;j++) xit[j]=xi[j][i]; 
   cptcoveff=0;        fptt=(*fret); 
    #ifdef DEBUG
   for (k=0; k<19; k++) Ndum[k]=0;        printf("fret=%lf \n",*fret);
   for (k=1; k<=7; k++) ncodemax[k]=0;        fprintf(ficlog,"fret=%lf \n",*fret);
   #endif
   for (j=1; j<=(cptcovn+2*cptcovprod); j++) {        printf("%d",i);fflush(stdout);
     for (i=1; i<=imx; i++) {        fprintf(ficlog,"%d",i);fflush(ficlog);
       ij=(int)(covar[Tvar[j]][i]);        linmin(p,xit,n,fret,func); 
       Ndum[ij]++;        if (fabs(fptt-(*fret)) > del) { 
       /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/          del=fabs(fptt-(*fret)); 
       if (ij > cptcode) cptcode=ij;          ibig=i; 
     }        } 
   #ifdef DEBUG
     for (i=0; i<=cptcode; i++) {        printf("%d %.12e",i,(*fret));
       if(Ndum[i]!=0) ncodemax[j]++;        fprintf(ficlog,"%d %.12e",i,(*fret));
     }        for (j=1;j<=n;j++) {
     ij=1;          xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
           printf(" x(%d)=%.12e",j,xit[j]);
           fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
     for (i=1; i<=ncodemax[j]; i++) {        }
       for (k=0; k<=19; k++) {        for(j=1;j<=n;j++) {
         if (Ndum[k] != 0) {          printf(" p=%.12e",p[j]);
           nbcode[Tvar[j]][ij]=k;          fprintf(ficlog," p=%.12e",p[j]);
           ij++;        }
         }        printf("\n");
         if (ij > ncodemax[j]) break;        fprintf(ficlog,"\n");
       }    #endif
     }      } 
   }        if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) {
   #ifdef DEBUG
  for (k=0; k<19; k++) Ndum[k]=0;        int k[2],l;
         k[0]=1;
  for (i=1; i<=ncovmodel; i++) {        k[1]=-1;
       ij=Tvar[i];        printf("Max: %.12e",(*func)(p));
       Ndum[ij]++;        fprintf(ficlog,"Max: %.12e",(*func)(p));
     }        for (j=1;j<=n;j++) {
           printf(" %.12e",p[j]);
  ij=1;          fprintf(ficlog," %.12e",p[j]);
  for (i=1; i<=10; i++) {        }
    if((Ndum[i]!=0) && (i<=ncov)){        printf("\n");
      Tvaraff[ij]=i;        fprintf(ficlog,"\n");
      ij++;        for(l=0;l<=1;l++) {
    }          for (j=1;j<=n;j++) {
  }            ptt[j]=p[j]+(p[j]-pt[j])*k[l];
              printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
     cptcoveff=ij-1;            fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
 }          }
           printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
 /*********** Health Expectancies ****************/          fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
         }
 void evsij(char fileres[], double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int ij)  #endif
 {  
   /* Health expectancies */  
   int i, j, nhstepm, hstepm, h;        free_vector(xit,1,n); 
   double age, agelim,hf;        free_vector(xits,1,n); 
   double ***p3mat;        free_vector(ptt,1,n); 
          free_vector(pt,1,n); 
   fprintf(ficreseij,"# Health expectancies\n");        return; 
   fprintf(ficreseij,"# Age");      } 
   for(i=1; i<=nlstate;i++)      if (*iter == ITMAX) nrerror("powell exceeding maximum iterations."); 
     for(j=1; j<=nlstate;j++)      for (j=1;j<=n;j++) { 
       fprintf(ficreseij," %1d-%1d",i,j);        ptt[j]=2.0*p[j]-pt[j]; 
   fprintf(ficreseij,"\n");        xit[j]=p[j]-pt[j]; 
         pt[j]=p[j]; 
   hstepm=1*YEARM; /*  Every j years of age (in month) */      } 
   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */      fptt=(*func)(ptt); 
       if (fptt < fp) { 
   agelim=AGESUP;        t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); 
   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */        if (t < 0.0) { 
     /* nhstepm age range expressed in number of stepm */          linmin(p,xit,n,fret,func); 
     nhstepm=(int) rint((agelim-age)*YEARM/stepm);          for (j=1;j<=n;j++) { 
     /* Typically if 20 years = 20*12/6=40 stepm */            xi[j][ibig]=xi[j][n]; 
     if (stepm >= YEARM) hstepm=1;            xi[j][n]=xit[j]; 
     nhstepm = nhstepm/hstepm;/* Expressed in hstepm, typically 40/4=10 */          }
     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);  #ifdef DEBUG
     /* Computed by stepm unit matrices, product of hstepm matrices, stored          printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */          fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
     hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, ij);            for(j=1;j<=n;j++){
             printf(" %.12e",xit[j]);
             fprintf(ficlog," %.12e",xit[j]);
     for(i=1; i<=nlstate;i++)          }
       for(j=1; j<=nlstate;j++)          printf("\n");
         for (h=0, eij[i][j][(int)age]=0; h<=nhstepm; h++){          fprintf(ficlog,"\n");
           eij[i][j][(int)age] +=p3mat[i][j][h];  #endif
         }        }
          } 
     hf=1;    } 
     if (stepm >= YEARM) hf=stepm/YEARM;  } 
     fprintf(ficreseij,"%.0f",age );  
     for(i=1; i<=nlstate;i++)  /**** Prevalence limit (stable or period prevalence)  ****************/
       for(j=1; j<=nlstate;j++){  
         fprintf(ficreseij," %.4f", hf*eij[i][j][(int)age]);  double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int ij)
       }  {
     fprintf(ficreseij,"\n");    /* Computes the prevalence limit in each live state at age x by left multiplying the unit
     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);       matrix by transitions matrix until convergence is reached */
   }  
 }    int i, ii,j,k;
     double min, max, maxmin, maxmax,sumnew=0.;
 /************ Variance ******************/    /* double **matprod2(); */ /* test */
 void varevsij(char fileres[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij)    double **out, cov[NCOVMAX+1], **pmij();
 {    double **newm;
   /* Variance of health expectancies */    double agefin, delaymax=50 ; /* Max number of years to converge */
   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/  
   double **newm;    for (ii=1;ii<=nlstate+ndeath;ii++)
   double **dnewm,**doldm;      for (j=1;j<=nlstate+ndeath;j++){
   int i, j, nhstepm, hstepm, h;        oldm[ii][j]=(ii==j ? 1.0 : 0.0);
   int k, cptcode;      }
    double *xp;  
   double **gp, **gm;     cov[1]=1.;
   double ***gradg, ***trgradg;   
   double ***p3mat;   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
   double age,agelim;    for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
   int theta;      newm=savm;
       /* Covariates have to be included here again */
    fprintf(ficresvij,"# Covariances of life expectancies\n");      cov[2]=agefin;
   fprintf(ficresvij,"# Age");      
   for(i=1; i<=nlstate;i++)      for (k=1; k<=cptcovn;k++) {
     for(j=1; j<=nlstate;j++)        cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]];
       fprintf(ficresvij," Cov(e%1d, e%1d)",i,j);        /*printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtab[%d][Tvar[%d]]=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtab[ij][Tvar[k]]],cov[2+k], ij, k, codtab[ij][Tvar[k]]);*/
   fprintf(ficresvij,"\n");      }
       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
   xp=vector(1,npar);      /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
   dnewm=matrix(1,nlstate,1,npar);      /*   cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]] * nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]]; */
   doldm=matrix(1,nlstate,1,nlstate);      
        /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
   hstepm=1*YEARM; /* Every year of age */      /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */      /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
   agelim = AGESUP;      /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */      /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */      out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
     if (stepm >= YEARM) hstepm=1;      
     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */      savm=oldm;
     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);      oldm=newm;
     gradg=ma3x(0,nhstepm,1,npar,1,nlstate);      maxmax=0.;
     gp=matrix(0,nhstepm,1,nlstate);      for(j=1;j<=nlstate;j++){
     gm=matrix(0,nhstepm,1,nlstate);        min=1.;
         max=0.;
     for(theta=1; theta <=npar; theta++){        for(i=1; i<=nlstate; i++) {
       for(i=1; i<=npar; i++){ /* Computes gradient */          sumnew=0;
         xp[i] = x[i] + (i==theta ?delti[theta]:0);          for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
       }          prlim[i][j]= newm[i][j]/(1-sumnew);
       hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);            /*printf(" prevalim i=%d, j=%d, prmlim[%d][%d]=%f, agefin=%d \n", i, j, i, j, prlim[i][j],(int)agefin);*/
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);          max=FMAX(max,prlim[i][j]);
       for(j=1; j<= nlstate; j++){          min=FMIN(min,prlim[i][j]);
         for(h=0; h<=nhstepm; h++){        }
           for(i=1, gp[h][j]=0.;i<=nlstate;i++)        maxmin=max-min;
             gp[h][j] += prlim[i][i]*p3mat[i][j][h];        maxmax=FMAX(maxmax,maxmin);
         }      }
       }      if(maxmax < ftolpl){
            return prlim;
       for(i=1; i<=npar; i++) /* Computes gradient */      }
         xp[i] = x[i] - (i==theta ?delti[theta]:0);    }
       hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);    }
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);  
       for(j=1; j<= nlstate; j++){  /*************** transition probabilities ***************/ 
         for(h=0; h<=nhstepm; h++){  
           for(i=1, gm[h][j]=0.;i<=nlstate;i++)  double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
             gm[h][j] += prlim[i][i]*p3mat[i][j][h];  {
         }    /* According to parameters values stored in x and the covariate's values stored in cov,
       }       computes the probability to be observed in state j being in state i by appying the
       for(j=1; j<= nlstate; j++)       model to the ncovmodel covariates (including constant and age).
         for(h=0; h<=nhstepm; h++){       lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];       and, according on how parameters are entered, the position of the coefficient xij(nc) of the
         }       ncth covariate in the global vector x is given by the formula:
     } /* End theta */       j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
        j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
     trgradg =ma3x(0,nhstepm,1,nlstate,1,npar);       Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
        sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
     for(h=0; h<=nhstepm; h++)       Outputs ps[i][j] the probability to be observed in j being in j according to
       for(j=1; j<=nlstate;j++)       the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
         for(theta=1; theta <=npar; theta++)    */
           trgradg[h][j][theta]=gradg[h][theta][j];    double s1, lnpijopii;
     /*double t34;*/
     for(i=1;i<=nlstate;i++)    int i,j,j1, nc, ii, jj;
       for(j=1;j<=nlstate;j++)  
         vareij[i][j][(int)age] =0.;      for(i=1; i<= nlstate; i++){
     for(h=0;h<=nhstepm;h++){        for(j=1; j<i;j++){
       for(k=0;k<=nhstepm;k++){          for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);            /*lnpijopii += param[i][j][nc]*cov[nc];*/
         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);            lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
         for(i=1;i<=nlstate;i++)  /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
           for(j=1;j<=nlstate;j++)          }
             vareij[i][j][(int)age] += doldm[i][j];          ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
       }  /*      printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
     }        }
     h=1;        for(j=i+1; j<=nlstate+ndeath;j++){
     if (stepm >= YEARM) h=stepm/YEARM;          for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
     fprintf(ficresvij,"%.0f ",age );            /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
     for(i=1; i<=nlstate;i++)            lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
       for(j=1; j<=nlstate;j++){  /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
         fprintf(ficresvij," %.4f", h*vareij[i][j][(int)age]);          }
       }          ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
     fprintf(ficresvij,"\n");        }
     free_matrix(gp,0,nhstepm,1,nlstate);      }
     free_matrix(gm,0,nhstepm,1,nlstate);      
     free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);      for(i=1; i<= nlstate; i++){
     free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);        s1=0;
     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);        for(j=1; j<i; j++){
   } /* End age */          s1+=exp(ps[i][j]); /* In fact sums pij/pii */
            /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
   free_vector(xp,1,npar);        }
   free_matrix(doldm,1,nlstate,1,npar);        for(j=i+1; j<=nlstate+ndeath; j++){
   free_matrix(dnewm,1,nlstate,1,nlstate);          s1+=exp(ps[i][j]); /* In fact sums pij/pii */
           /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
 }        }
         /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
 /************ Variance of prevlim ******************/        ps[i][i]=1./(s1+1.);
 void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij)        /* Computing other pijs */
 {        for(j=1; j<i; j++)
   /* Variance of prevalence limit */          ps[i][j]= exp(ps[i][j])*ps[i][i];
   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/        for(j=i+1; j<=nlstate+ndeath; j++)
   double **newm;          ps[i][j]= exp(ps[i][j])*ps[i][i];
   double **dnewm,**doldm;        /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
   int i, j, nhstepm, hstepm;      } /* end i */
   int k, cptcode;      
   double *xp;      for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
   double *gp, *gm;        for(jj=1; jj<= nlstate+ndeath; jj++){
   double **gradg, **trgradg;          ps[ii][jj]=0;
   double age,agelim;          ps[ii][ii]=1;
   int theta;        }
          }
   fprintf(ficresvpl,"# Standard deviation of prevalences limit\n");      
   fprintf(ficresvpl,"# Age");      
   for(i=1; i<=nlstate;i++)      /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
       fprintf(ficresvpl," %1d-%1d",i,i);      /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
   fprintf(ficresvpl,"\n");      /*  printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
       /*   } */
   xp=vector(1,npar);      /*   printf("\n "); */
   dnewm=matrix(1,nlstate,1,npar);      /* } */
   doldm=matrix(1,nlstate,1,nlstate);      /* printf("\n ");printf("%lf ",cov[2]);*/
        /*
   hstepm=1*YEARM; /* Every year of age */        for(i=1; i<= npar; i++) printf("%f ",x[i]);
   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */        goto end;*/
   agelim = AGESUP;      return ps;
   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */  }
     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */  
     if (stepm >= YEARM) hstepm=1;  /**************** Product of 2 matrices ******************/
     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */  
     gradg=matrix(1,npar,1,nlstate);  double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
     gp=vector(1,nlstate);  {
     gm=vector(1,nlstate);    /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
        b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
     for(theta=1; theta <=npar; theta++){    /* in, b, out are matrice of pointers which should have been initialized 
       for(i=1; i<=npar; i++){ /* Computes gradient */       before: only the contents of out is modified. The function returns
         xp[i] = x[i] + (i==theta ?delti[theta]:0);       a pointer to pointers identical to out */
       }    int i, j, k;
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);    for(i=nrl; i<= nrh; i++)
       for(i=1;i<=nlstate;i++)      for(k=ncolol; k<=ncoloh; k++){
         gp[i] = prlim[i][i];        out[i][k]=0.;
            for(j=ncl; j<=nch; j++)
       for(i=1; i<=npar; i++) /* Computes gradient */          out[i][k] +=in[i][j]*b[j][k];
         xp[i] = x[i] - (i==theta ?delti[theta]:0);      }
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);    return out;
       for(i=1;i<=nlstate;i++)  }
         gm[i] = prlim[i][i];  
   
       for(i=1;i<=nlstate;i++)  /************* Higher Matrix Product ***************/
         gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];  
     } /* End theta */  double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij )
   {
     trgradg =matrix(1,nlstate,1,npar);    /* Computes the transition matrix starting at age 'age' over 
        'nhstepm*hstepm*stepm' months (i.e. until
     for(j=1; j<=nlstate;j++)       age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
       for(theta=1; theta <=npar; theta++)       nhstepm*hstepm matrices. 
         trgradg[j][theta]=gradg[theta][j];       Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
        (typically every 2 years instead of every month which is too big 
     for(i=1;i<=nlstate;i++)       for the memory).
       varpl[i][(int)age] =0.;       Model is determined by parameters x and covariates have to be 
     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);       included manually here. 
     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);  
     for(i=1;i<=nlstate;i++)       */
       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */  
     int i, j, d, h, k;
     fprintf(ficresvpl,"%.0f ",age );    double **out, cov[NCOVMAX+1];
     for(i=1; i<=nlstate;i++)    double **newm;
       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));  
     fprintf(ficresvpl,"\n");    /* Hstepm could be zero and should return the unit matrix */
     free_vector(gp,1,nlstate);    for (i=1;i<=nlstate+ndeath;i++)
     free_vector(gm,1,nlstate);      for (j=1;j<=nlstate+ndeath;j++){
     free_matrix(gradg,1,npar,1,nlstate);        oldm[i][j]=(i==j ? 1.0 : 0.0);
     free_matrix(trgradg,1,nlstate,1,npar);        po[i][j][0]=(i==j ? 1.0 : 0.0);
   } /* End age */      }
     /* Even if hstepm = 1, at least one multiplication by the unit matrix */
   free_vector(xp,1,npar);    for(h=1; h <=nhstepm; h++){
   free_matrix(doldm,1,nlstate,1,npar);      for(d=1; d <=hstepm; d++){
   free_matrix(dnewm,1,nlstate,1,nlstate);        newm=savm;
         /* Covariates have to be included here again */
 }        cov[1]=1.;
         cov[2]=age+((h-1)*hstepm + (d-1))*stepm/YEARM;
         for (k=1; k<=cptcovn;k++) 
           cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]];
 /***********************************************/        for (k=1; k<=cptcovage;k++)
 /**************** Main Program *****************/          cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];
 /***********************************************/        for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
           cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];
 /*int main(int argc, char *argv[])*/  
 int main()  
 {        /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
         /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
   int i,j, k, n=MAXN,iter,m,size,cptcode, cptcod;        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
   double agedeb, agefin,hf;                     pmij(pmmij,cov,ncovmodel,x,nlstate));
   double agemin=1.e20, agemax=-1.e20;        savm=oldm;
         oldm=newm;
   double fret;      }
   double **xi,tmp,delta;      for(i=1; i<=nlstate+ndeath; i++)
         for(j=1;j<=nlstate+ndeath;j++) {
   double dum; /* Dummy variable */          po[i][j][h]=newm[i][j];
   double ***p3mat;          /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
   int *indx;        }
   char line[MAXLINE], linepar[MAXLINE];      /*printf("h=%d ",h);*/
   char title[MAXLINE];    } /* end h */
   char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH];  /*     printf("\n H=%d \n",h); */
   char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filereso[FILENAMELENGTH];    return po;
   char filerest[FILENAMELENGTH];  }
   char fileregp[FILENAMELENGTH];  
   char path[80],pathc[80],pathcd[80],pathtot[80],model[20];  
   int firstobs=1, lastobs=10;  /*************** log-likelihood *************/
   int sdeb, sfin; /* Status at beginning and end */  double func( double *x)
   int c,  h , cpt,l;  {
   int ju,jl, mi;    int i, ii, j, k, mi, d, kk;
   int i1,j1, k1,k2,k3,jk,aa,bb, stepsize, ij;    double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
   int jnais,jdc,jint4,jint1,jint2,jint3,**outcome,**adl,*tab;    double **out;
      double sw; /* Sum of weights */
   int hstepm, nhstepm;    double lli; /* Individual log likelihood */
   double bage, fage, age, agelim, agebase;    int s1, s2;
   double ftolpl=FTOL;    double bbh, survp;
   double **prlim;    long ipmx;
   double *severity;    /*extern weight */
   double ***param; /* Matrix of parameters */    /* We are differentiating ll according to initial status */
   double  *p;    /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
   double **matcov; /* Matrix of covariance */    /*for(i=1;i<imx;i++) 
   double ***delti3; /* Scale */      printf(" %d\n",s[4][i]);
   double *delti; /* Scale */    */
   double ***eij, ***vareij;    cov[1]=1.;
   double **varpl; /* Variances of prevalence limits by age */  
   double *epj, vepp;    for(k=1; k<=nlstate; k++) ll[k]=0.;
   char version[80]="Imach version 62c, May 1999, INED-EUROREVES ";  
   char *alph[]={"a","a","b","c","d","e"}, str[4];    if(mle==1){
       for (i=1,ipmx=0, sw=0.; i<=imx; i++){
   char z[1]="c", occ;        /* Computes the values of the ncovmodel covariates of the model
 #include <sys/time.h>           depending if the covariates are fixed or variying (age dependent) and stores them in cov[]
 #include <time.h>           Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
   char stra[80], strb[80], strc[80], strd[80],stre[80],modelsav[80];           to be observed in j being in i according to the model.
   /* long total_usecs;         */
   struct timeval start_time, end_time;        for (k=1; k<=cptcovn;k++){ /* Simple and product covariates without age* products */
            cov[2+k]=covar[Tvar[k]][i];
   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */        }
         /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
            is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
   printf("\nIMACH, Version 0.64a");           has been calculated etc */
   printf("\nEnter the parameter file name: ");        for(mi=1; mi<= wav[i]-1; mi++){
           for (ii=1;ii<=nlstate+ndeath;ii++)
 #ifdef windows            for (j=1;j<=nlstate+ndeath;j++){
   scanf("%s",pathtot);              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
   getcwd(pathcd, size);              savm[ii][j]=(ii==j ? 1.0 : 0.0);
   /*cygwin_split_path(pathtot,path,optionfile);            }
     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/          for(d=0; d<dh[mi][i]; d++){
   /* cutv(path,optionfile,pathtot,'\\');*/            newm=savm;
             cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
 split(pathtot, path,optionfile);            for (kk=1; kk<=cptcovage;kk++) {
   chdir(path);              cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2]; /* Tage[kk] gives the data-covariate associated with age */
   replace(pathc,path);            }
 #endif            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
 #ifdef unix                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
   scanf("%s",optionfile);            savm=oldm;
 #endif            oldm=newm;
           } /* end mult */
 /*-------- arguments in the command line --------*/        
           /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
   strcpy(fileres,"r");          /* But now since version 0.9 we anticipate for bias at large stepm.
   strcat(fileres, optionfile);           * If stepm is larger than one month (smallest stepm) and if the exact delay 
            * (in months) between two waves is not a multiple of stepm, we rounded to 
   /*---------arguments file --------*/           * the nearest (and in case of equal distance, to the lowest) interval but now
            * we keep into memory the bias bh[mi][i] and also the previous matrix product
   if((ficpar=fopen(optionfile,"r"))==NULL)    {           * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
     printf("Problem with optionfile %s\n",optionfile);           * probability in order to take into account the bias as a fraction of the way
     goto end;           * from savm to out if bh is negative or even beyond if bh is positive. bh varies
   }           * -stepm/2 to stepm/2 .
            * For stepm=1 the results are the same as for previous versions of Imach.
   strcpy(filereso,"o");           * For stepm > 1 the results are less biased than in previous versions. 
   strcat(filereso,fileres);           */
   if((ficparo=fopen(filereso,"w"))==NULL) {          s1=s[mw[mi][i]][i];
     printf("Problem with Output resultfile: %s\n", filereso);goto end;          s2=s[mw[mi+1][i]][i];
   }          bbh=(double)bh[mi][i]/(double)stepm; 
           /* bias bh is positive if real duration
   /* Reads comments: lines beginning with '#' */           * is higher than the multiple of stepm and negative otherwise.
   while((c=getc(ficpar))=='#' && c!= EOF){           */
     ungetc(c,ficpar);          /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
     fgets(line, MAXLINE, ficpar);          if( s2 > nlstate){ 
     puts(line);            /* i.e. if s2 is a death state and if the date of death is known 
     fputs(line,ficparo);               then the contribution to the likelihood is the probability to 
   }               die between last step unit time and current  step unit time, 
   ungetc(c,ficpar);               which is also equal to probability to die before dh 
                minus probability to die before dh-stepm . 
   fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncov=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncov, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model);               In version up to 0.92 likelihood was computed
   printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncov=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncov, nlstate,ndeath, maxwav, mle, weightopt,model);          as if date of death was unknown. Death was treated as any other
   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncov=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncov,nlstate,ndeath,maxwav, mle, weightopt,model);          health state: the date of the interview describes the actual state
           and not the date of a change in health state. The former idea was
   covar=matrix(0,NCOVMAX,1,n);          to consider that at each interview the state was recorded
   cptcovn=0;          (healthy, disable or death) and IMaCh was corrected; but when we
   if (strlen(model)>1) cptcovn=nbocc(model,'+')+1;          introduced the exact date of death then we should have modified
           the contribution of an exact death to the likelihood. This new
   ncovmodel=2+cptcovn;          contribution is smaller and very dependent of the step unit
   nvar=ncovmodel-1; /* Suppressing age as a basic covariate */          stepm. It is no more the probability to die between last interview
            and month of death but the probability to survive from last
   /* Read guess parameters */          interview up to one month before death multiplied by the
   /* Reads comments: lines beginning with '#' */          probability to die within a month. Thanks to Chris
   while((c=getc(ficpar))=='#' && c!= EOF){          Jackson for correcting this bug.  Former versions increased
     ungetc(c,ficpar);          mortality artificially. The bad side is that we add another loop
     fgets(line, MAXLINE, ficpar);          which slows down the processing. The difference can be up to 10%
     puts(line);          lower mortality.
     fputs(line,ficparo);            */
   }            lli=log(out[s1][s2] - savm[s1][s2]);
   ungetc(c,ficpar);  
    
   param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);          } else if  (s2==-2) {
     for(i=1; i <=nlstate; i++)            for (j=1,survp=0. ; j<=nlstate; j++) 
     for(j=1; j <=nlstate+ndeath-1; j++){              survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
       fscanf(ficpar,"%1d%1d",&i1,&j1);            /*survp += out[s1][j]; */
       fprintf(ficparo,"%1d%1d",i1,j1);            lli= log(survp);
       printf("%1d%1d",i,j);          }
       for(k=1; k<=ncovmodel;k++){          
         fscanf(ficpar," %lf",&param[i][j][k]);          else if  (s2==-4) { 
         printf(" %lf",param[i][j][k]);            for (j=3,survp=0. ; j<=nlstate; j++)  
         fprintf(ficparo," %lf",param[i][j][k]);              survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
       }            lli= log(survp); 
       fscanf(ficpar,"\n");          } 
       printf("\n");  
       fprintf(ficparo,"\n");          else if  (s2==-5) { 
     }            for (j=1,survp=0. ; j<=2; j++)  
                survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
   npar= (nlstate+ndeath-1)*nlstate*ncovmodel;            lli= log(survp); 
   p=param[1][1];          } 
            
   /* Reads comments: lines beginning with '#' */          else{
   while((c=getc(ficpar))=='#' && c!= EOF){            lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
     ungetc(c,ficpar);            /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
     fgets(line, MAXLINE, ficpar);          } 
     puts(line);          /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
     fputs(line,ficparo);          /*if(lli ==000.0)*/
   }          /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
   ungetc(c,ficpar);          ipmx +=1;
           sw += weight[i];
   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
   delti=vector(1,npar); /* Scale of each paramater (output from hesscov) */        } /* end of wave */
   for(i=1; i <=nlstate; i++){      } /* end of individual */
     for(j=1; j <=nlstate+ndeath-1; j++){    }  else if(mle==2){
       fscanf(ficpar,"%1d%1d",&i1,&j1);      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
       printf("%1d%1d",i,j);        for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
       fprintf(ficparo,"%1d%1d",i1,j1);        for(mi=1; mi<= wav[i]-1; mi++){
       for(k=1; k<=ncovmodel;k++){          for (ii=1;ii<=nlstate+ndeath;ii++)
         fscanf(ficpar,"%le",&delti3[i][j][k]);            for (j=1;j<=nlstate+ndeath;j++){
         printf(" %le",delti3[i][j][k]);              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
         fprintf(ficparo," %le",delti3[i][j][k]);              savm[ii][j]=(ii==j ? 1.0 : 0.0);
       }            }
       fscanf(ficpar,"\n");          for(d=0; d<=dh[mi][i]; d++){
       printf("\n");            newm=savm;
       fprintf(ficparo,"\n");            cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
     }            for (kk=1; kk<=cptcovage;kk++) {
   }              cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
   delti=delti3[1][1];            }
              out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
   /* Reads comments: lines beginning with '#' */                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
   while((c=getc(ficpar))=='#' && c!= EOF){            savm=oldm;
     ungetc(c,ficpar);            oldm=newm;
     fgets(line, MAXLINE, ficpar);          } /* end mult */
     puts(line);        
     fputs(line,ficparo);          s1=s[mw[mi][i]][i];
   }          s2=s[mw[mi+1][i]][i];
   ungetc(c,ficpar);          bbh=(double)bh[mi][i]/(double)stepm; 
            lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
   matcov=matrix(1,npar,1,npar);          ipmx +=1;
   for(i=1; i <=npar; i++){          sw += weight[i];
     fscanf(ficpar,"%s",&str);          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
     printf("%s",str);        } /* end of wave */
     fprintf(ficparo,"%s",str);      } /* end of individual */
     for(j=1; j <=i; j++){    }  else if(mle==3){  /* exponential inter-extrapolation */
       fscanf(ficpar," %le",&matcov[i][j]);      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
       printf(" %.5le",matcov[i][j]);        for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
       fprintf(ficparo," %.5le",matcov[i][j]);        for(mi=1; mi<= wav[i]-1; mi++){
     }          for (ii=1;ii<=nlstate+ndeath;ii++)
     fscanf(ficpar,"\n");            for (j=1;j<=nlstate+ndeath;j++){
     printf("\n");              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
     fprintf(ficparo,"\n");              savm[ii][j]=(ii==j ? 1.0 : 0.0);
   }            }
   for(i=1; i <=npar; i++)          for(d=0; d<dh[mi][i]; d++){
     for(j=i+1;j<=npar;j++)            newm=savm;
       matcov[i][j]=matcov[j][i];            cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
                for (kk=1; kk<=cptcovage;kk++) {
   printf("\n");              cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
             }
             out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
     /*-------- data file ----------*/                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
     if((ficres =fopen(fileres,"w"))==NULL) {            savm=oldm;
       printf("Problem with resultfile: %s\n", fileres);goto end;            oldm=newm;
     }          } /* end mult */
     fprintf(ficres,"#%s\n",version);        
              s1=s[mw[mi][i]][i];
     if((fic=fopen(datafile,"r"))==NULL)    {          s2=s[mw[mi+1][i]][i];
       printf("Problem with datafile: %s\n", datafile);goto end;          bbh=(double)bh[mi][i]/(double)stepm; 
     }          lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
           ipmx +=1;
     n= lastobs;          sw += weight[i];
     severity = vector(1,maxwav);          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
     outcome=imatrix(1,maxwav+1,1,n);        } /* end of wave */
     num=ivector(1,n);      } /* end of individual */
     moisnais=vector(1,n);    }else if (mle==4){  /* ml=4 no inter-extrapolation */
     annais=vector(1,n);      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
     moisdc=vector(1,n);        for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
     andc=vector(1,n);        for(mi=1; mi<= wav[i]-1; mi++){
     agedc=vector(1,n);          for (ii=1;ii<=nlstate+ndeath;ii++)
     cod=ivector(1,n);            for (j=1;j<=nlstate+ndeath;j++){
     weight=vector(1,n);              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
     for(i=1;i<=n;i++) weight[i]=1.0; /* Equal weights, 1 by default */              savm[ii][j]=(ii==j ? 1.0 : 0.0);
     mint=matrix(1,maxwav,1,n);            }
     anint=matrix(1,maxwav,1,n);          for(d=0; d<dh[mi][i]; d++){
     s=imatrix(1,maxwav+1,1,n);            newm=savm;
     adl=imatrix(1,maxwav+1,1,n);                cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
     tab=ivector(1,NCOVMAX);            for (kk=1; kk<=cptcovage;kk++) {
     ncodemax=ivector(1,8);              cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
             }
     i=1;          
     while (fgets(line, MAXLINE, fic) != NULL)    {            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
       if ((i >= firstobs) && (i <=lastobs)) {                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                    savm=oldm;
         for (j=maxwav;j>=1;j--){            oldm=newm;
           cutv(stra, strb,line,' '); s[j][i]=atoi(strb);          } /* end mult */
           strcpy(line,stra);        
           cutv(stra, strb,line,'/'); anint[j][i]=(double)(atoi(strb)); strcpy(line,stra);          s1=s[mw[mi][i]][i];
           cutv(stra, strb,line,' '); mint[j][i]=(double)(atoi(strb)); strcpy(line,stra);          s2=s[mw[mi+1][i]][i];
         }          if( s2 > nlstate){ 
                    lli=log(out[s1][s2] - savm[s1][s2]);
         cutv(stra, strb,line,'/'); andc[i]=(double)(atoi(strb)); strcpy(line,stra);          }else{
         cutv(stra, strb,line,' '); moisdc[i]=(double)(atoi(strb)); strcpy(line,stra);            lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
           }
         cutv(stra, strb,line,'/'); annais[i]=(double)(atoi(strb)); strcpy(line,stra);          ipmx +=1;
         cutv(stra, strb,line,' '); moisnais[i]=(double)(atoi(strb)); strcpy(line,stra);          sw += weight[i];
           ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
         cutv(stra, strb,line,' '); weight[i]=(double)(atoi(strb)); strcpy(line,stra);  /*      printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
         for (j=ncov;j>=1;j--){        } /* end of wave */
           cutv(stra, strb,line,' '); covar[j][i]=(double)(atoi(strb)); strcpy(line,stra);      } /* end of individual */
         }    }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
         num[i]=atol(stra);      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
         for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
         /*printf("%d %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]), (weight[i]), (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i]));*/        for(mi=1; mi<= wav[i]-1; mi++){
           for (ii=1;ii<=nlstate+ndeath;ii++)
         i=i+1;            for (j=1;j<=nlstate+ndeath;j++){
       }              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
     }              savm[ii][j]=(ii==j ? 1.0 : 0.0);
             }
     /*scanf("%d",i);*/          for(d=0; d<dh[mi][i]; d++){
   imx=i-1; /* Number of individuals */            newm=savm;
             cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
   /* Calculation of the number of parameter from char model*/            for (kk=1; kk<=cptcovage;kk++) {
   Tvar=ivector(1,15);              cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
   Tprod=ivector(1,15);            }
   Tvaraff=ivector(1,15);          
   Tvard=imatrix(1,15,1,2);            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
   Tage=ivector(1,15);                               1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                savm=oldm;
   if (strlen(model) >1){            oldm=newm;
     j=0, j1=0, k1=1, k2=1;          } /* end mult */
     j=nbocc(model,'+');        
     j1=nbocc(model,'*');          s1=s[mw[mi][i]][i];
     cptcovn=j+1;          s2=s[mw[mi+1][i]][i];
     cptcovprod=j1;          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
              ipmx +=1;
              sw += weight[i];
     strcpy(modelsav,model);          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
     if ((strcmp(model,"age")==0) || (strcmp(model,"age*age")==0)){          /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
       printf("Error. Non available option model=%s ",model);        } /* end of wave */
       goto end;      } /* end of individual */
     }    } /* End of if */
        for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
     for(i=(j+1); i>=1;i--){    /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
       cutv(stra,strb,modelsav,'+');    l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
       if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav);    return -l;
       /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/  }
       /*scanf("%d",i);*/  
       if (strchr(strb,'*')) {  /*************** log-likelihood *************/
         cutv(strd,strc,strb,'*');  double funcone( double *x)
         if (strcmp(strc,"age")==0) {  {
           cptcovprod--;    /* Same as likeli but slower because of a lot of printf and if */
           cutv(strb,stre,strd,'V');    int i, ii, j, k, mi, d, kk;
           Tvar[i]=atoi(stre);    double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
           cptcovage++;    double **out;
             Tage[cptcovage]=i;    double lli; /* Individual log likelihood */
             /*printf("stre=%s ", stre);*/    double llt;
         }    int s1, s2;
         else if (strcmp(strd,"age")==0) {    double bbh, survp;
           cptcovprod--;    /*extern weight */
           cutv(strb,stre,strc,'V');    /* We are differentiating ll according to initial status */
           Tvar[i]=atoi(stre);    /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
           cptcovage++;    /*for(i=1;i<imx;i++) 
           Tage[cptcovage]=i;      printf(" %d\n",s[4][i]);
         }    */
         else {    cov[1]=1.;
           cutv(strb,stre,strc,'V');  
           Tvar[i]=ncov+k1;    for(k=1; k<=nlstate; k++) ll[k]=0.;
           cutv(strb,strc,strd,'V');  
           Tprod[k1]=i;    for (i=1,ipmx=0, sw=0.; i<=imx; i++){
           Tvard[k1][1]=atoi(strc);      for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
           Tvard[k1][2]=atoi(stre);      for(mi=1; mi<= wav[i]-1; mi++){
           Tvar[cptcovn+k2]=Tvard[k1][1];        for (ii=1;ii<=nlstate+ndeath;ii++)
           Tvar[cptcovn+k2+1]=Tvard[k1][2];          for (j=1;j<=nlstate+ndeath;j++){
           for (k=1; k<=lastobs;k++)            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
             covar[ncov+k1][k]=covar[atoi(stre)][k]*covar[atoi(strc)][k];            savm[ii][j]=(ii==j ? 1.0 : 0.0);
           k1++;          }
           k2=k2+2;        for(d=0; d<dh[mi][i]; d++){
         }          newm=savm;
       }          cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
       else {          for (kk=1; kk<=cptcovage;kk++) {
         /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/            cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
        /*  scanf("%d",i);*/          }
       cutv(strd,strc,strb,'V');          /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
       Tvar[i]=atoi(strc);          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
       }                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
       strcpy(modelsav,stra);            /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
       /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);          /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
         scanf("%d",i);*/          savm=oldm;
     }          oldm=newm;
 }        } /* end mult */
          
   /*printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);        s1=s[mw[mi][i]][i];
   printf("cptcovprod=%d ", cptcovprod);        s2=s[mw[mi+1][i]][i];
   scanf("%d ",i);*/        bbh=(double)bh[mi][i]/(double)stepm; 
     fclose(fic);        /* bias is positive if real duration
          * is higher than the multiple of stepm and negative otherwise.
     /*  if(mle==1){*/         */
     if (weightopt != 1) { /* Maximisation without weights*/        if( s2 > nlstate && (mle <5) ){  /* Jackson */
       for(i=1;i<=n;i++) weight[i]=1.0;          lli=log(out[s1][s2] - savm[s1][s2]);
     }        } else if  (s2==-2) {
     /*-calculation of age at interview from date of interview and age at death -*/          for (j=1,survp=0. ; j<=nlstate; j++) 
     agev=matrix(1,maxwav,1,imx);            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
              lli= log(survp);
     for (i=1; i<=imx; i++)  {        }else if (mle==1){
       agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
       for(m=1; (m<= maxwav); m++){        } else if(mle==2){
         if(s[m][i] >0){          lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
           if (s[m][i] == nlstate+1) {        } else if(mle==3){  /* exponential inter-extrapolation */
             if(agedc[i]>0)          lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
               if(moisdc[i]!=99 && andc[i]!=9999)        } else if (mle==4){  /* mle=4 no inter-extrapolation */
               agev[m][i]=agedc[i];          lli=log(out[s1][s2]); /* Original formula */
             else {        } else{  /* mle=0 back to 1 */
               if (andc[i]!=9999){          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
               printf("Warning negative age at death: %d line:%d\n",num[i],i);          /*lli=log(out[s1][s2]); */ /* Original formula */
               agev[m][i]=-1;        } /* End of if */
               }        ipmx +=1;
             }        sw += weight[i];
           }        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
           else if(s[m][i] !=9){ /* Should no more exist */        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
             agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);        if(globpr){
             if(mint[m][i]==99 || anint[m][i]==9999)          fprintf(ficresilk,"%9ld %6d %2d %2d %1d %1d %3d %11.6f %8.4f\
               agev[m][i]=1;   %11.6f %11.6f %11.6f ", \
             else if(agev[m][i] <agemin){                  num[i],i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],
               agemin=agev[m][i];                  2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
               /*printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], agemin);*/          for(k=1,llt=0.,l=0.; k<=nlstate; k++){
             }            llt +=ll[k]*gipmx/gsw;
             else if(agev[m][i] >agemax){            fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
               agemax=agev[m][i];          }
              /* printf(" anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.0f\n",m,i,anint[m][i], i,annais[i], agemax);*/          fprintf(ficresilk," %10.6f\n", -llt);
             }        }
             /*agev[m][i]=anint[m][i]-annais[i];*/      } /* end of wave */
             /*   agev[m][i] = age[i]+2*m;*/    } /* end of individual */
           }    for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
           else { /* =9 */    /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
             agev[m][i]=1;    l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
             s[m][i]=-1;    if(globpr==0){ /* First time we count the contributions and weights */
           }      gipmx=ipmx;
         }      gsw=sw;
         else /*= 0 Unknown */    }
           agev[m][i]=1;    return -l;
       }  }
      
     }  
     for (i=1; i<=imx; i++)  {  /*************** function likelione ***********/
       for(m=1; (m<= maxwav); m++){  void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
         if (s[m][i] > (nlstate+ndeath)) {  {
           printf("Error: Wrong value in nlstate or ndeath\n");      /* This routine should help understanding what is done with 
           goto end;       the selection of individuals/waves and
         }       to check the exact contribution to the likelihood.
       }       Plotting could be done.
     }     */
     int k;
 printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, agemin, agemax);  
     if(*globpri !=0){ /* Just counts and sums, no printings */
     free_vector(severity,1,maxwav);      strcpy(fileresilk,"ilk"); 
     free_imatrix(outcome,1,maxwav+1,1,n);      strcat(fileresilk,fileres);
     free_vector(moisnais,1,n);      if((ficresilk=fopen(fileresilk,"w"))==NULL) {
     free_vector(annais,1,n);        printf("Problem with resultfile: %s\n", fileresilk);
     free_matrix(mint,1,maxwav,1,n);        fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
     free_matrix(anint,1,maxwav,1,n);      }
     free_vector(moisdc,1,n);      fprintf(ficresilk, "#individual(line's_record) s1 s2 wave# effective_wave# number_of_matrices_product pij weight -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
     free_vector(andc,1,n);      fprintf(ficresilk, "#num_i i s1 s2 mi mw dh likeli weight 2wlli out sav ");
       /*  i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
          for(k=1; k<=nlstate; k++) 
     wav=ivector(1,imx);        fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
     dh=imatrix(1,lastpass-firstpass+1,1,imx);      fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
     mw=imatrix(1,lastpass-firstpass+1,1,imx);    }
      
     /* Concatenates waves */    *fretone=(*funcone)(p);
       concatwav(wav, dh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);    if(*globpri !=0){
       fclose(ficresilk);
       fprintf(fichtm,"\n<br>File of contributions to the likelihood: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
       Tcode=ivector(1,100);      fflush(fichtm); 
       nbcode=imatrix(0,NCOVMAX,0,NCOVMAX);    } 
       ncodemax[1]=1;    return;
       if (cptcovn > 0) tricode(Tvar,nbcode,imx);  }
        
    codtab=imatrix(1,100,1,10);  
    h=0;  /*********** Maximum Likelihood Estimation ***************/
    m=pow(2,cptcoveff);  
    void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
    for(k=1;k<=cptcoveff; k++){  {
      for(i=1; i <=(m/pow(2,k));i++){    int i,j, iter;
        for(j=1; j <= ncodemax[k]; j++){    double **xi;
          for(cpt=1; cpt <=(m/pow(2,cptcoveff+1-k)); cpt++){    double fret;
            h++;    double fretone; /* Only one call to likelihood */
            if (h>m) h=1;codtab[h][k]=j;    /*  char filerespow[FILENAMELENGTH];*/
          }    xi=matrix(1,npar,1,npar);
        }    for (i=1;i<=npar;i++)
      }      for (j=1;j<=npar;j++)
    }        xi[i][j]=(i==j ? 1.0 : 0.0);
     printf("Powell\n");  fprintf(ficlog,"Powell\n");
     strcpy(filerespow,"pow"); 
    /*for(i=1; i <=m ;i++){    strcat(filerespow,fileres);
      for(k=1; k <=cptcovn; k++){    if((ficrespow=fopen(filerespow,"w"))==NULL) {
        printf("i=%d k=%d %d %d",i,k,codtab[i][k], cptcoveff);      printf("Problem with resultfile: %s\n", filerespow);
      }      fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
      printf("\n");    }
    }    fprintf(ficrespow,"# Powell\n# iter -2*LL");
    scanf("%d",i);*/    for (i=1;i<=nlstate;i++)
          for(j=1;j<=nlstate+ndeath;j++)
    /* Calculates basic frequencies. Computes observed prevalence at single age        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
        and prints on file fileres'p'. */    fprintf(ficrespow,"\n");
   freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax);  
     powell(p,xi,npar,ftol,&iter,&fret,func);
     pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */  
     oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */    free_matrix(xi,1,npar,1,npar);
     newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */    fclose(ficrespow);
     savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */    printf("\n#Number of iterations = %d, -2 Log likelihood = %.12f\n",iter,func(p));
     oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */    fprintf(ficlog,"\n#Number of iterations = %d, -2 Log likelihood = %.12f \n",iter,func(p));
        fprintf(ficres,"#Number of iterations = %d, -2 Log likelihood = %.12f \n",iter,func(p));
     /* For Powell, parameters are in a vector p[] starting at p[1]  
        so we point p on param[1][1] so that p[1] maps on param[1][1][1] */  }
     p=param[1][1]; /* *(*(*(param +1)+1)+0) */  
   /**** Computes Hessian and covariance matrix ***/
     if(mle==1){  void hesscov(double **matcov, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
     mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);  {
     }    double  **a,**y,*x,pd;
        double **hess;
     /*--------- results files --------------*/    int i, j,jk;
     fprintf(ficres,"\ntitle=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncov=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncov, nlstate, ndeath, maxwav, mle,weightopt,model);    int *indx;
      
    jk=1;    double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
    fprintf(ficres,"# Parameters\n");    double hessij(double p[], double delti[], int i, int j,double (*func)(double []),int npar);
    printf("# Parameters\n");    void lubksb(double **a, int npar, int *indx, double b[]) ;
    for(i=1,jk=1; i <=nlstate; i++){    void ludcmp(double **a, int npar, int *indx, double *d) ;
      for(k=1; k <=(nlstate+ndeath); k++){    double gompertz(double p[]);
        if (k != i)    hess=matrix(1,npar,1,npar);
          {  
            printf("%d%d ",i,k);    printf("\nCalculation of the hessian matrix. Wait...\n");
            fprintf(ficres,"%1d%1d ",i,k);    fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
            for(j=1; j <=ncovmodel; j++){    for (i=1;i<=npar;i++){
              printf("%f ",p[jk]);      printf("%d",i);fflush(stdout);
              fprintf(ficres,"%f ",p[jk]);      fprintf(ficlog,"%d",i);fflush(ficlog);
              jk++;     
            }       hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
            printf("\n");      
            fprintf(ficres,"\n");      /*  printf(" %f ",p[i]);
          }          printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
      }    }
    }    
  if(mle==1){    for (i=1;i<=npar;i++) {
     /* Computing hessian and covariance matrix */      for (j=1;j<=npar;j++)  {
     ftolhess=ftol; /* Usually correct */        if (j>i) { 
     hesscov(matcov, p, npar, delti, ftolhess, func);          printf(".%d%d",i,j);fflush(stdout);
  }          fprintf(ficlog,".%d%d",i,j);fflush(ficlog);
     fprintf(ficres,"# Scales\n");          hess[i][j]=hessij(p,delti,i,j,func,npar);
     printf("# Scales\n");          
      for(i=1,jk=1; i <=nlstate; i++){          hess[j][i]=hess[i][j];    
       for(j=1; j <=nlstate+ndeath; j++){          /*printf(" %lf ",hess[i][j]);*/
         if (j!=i) {        }
           fprintf(ficres,"%1d%1d",i,j);      }
           printf("%1d%1d",i,j);    }
           for(k=1; k<=ncovmodel;k++){    printf("\n");
             printf(" %.5e",delti[jk]);    fprintf(ficlog,"\n");
             fprintf(ficres," %.5e",delti[jk]);  
             jk++;    printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
           }    fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
           printf("\n");    
           fprintf(ficres,"\n");    a=matrix(1,npar,1,npar);
         }    y=matrix(1,npar,1,npar);
       }    x=vector(1,npar);
       }    indx=ivector(1,npar);
        for (i=1;i<=npar;i++)
     k=1;      for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
     fprintf(ficres,"# Covariance\n");    ludcmp(a,npar,indx,&pd);
     printf("# Covariance\n");  
     for(i=1;i<=npar;i++){    for (j=1;j<=npar;j++) {
       /*  if (k>nlstate) k=1;      for (i=1;i<=npar;i++) x[i]=0;
       i1=(i-1)/(ncovmodel*nlstate)+1;      x[j]=1;
       fprintf(ficres,"%s%d%d",alph[k],i1,tab[i]);      lubksb(a,npar,indx,x);
       printf("%s%d%d",alph[k],i1,tab[i]);*/      for (i=1;i<=npar;i++){ 
       fprintf(ficres,"%3d",i);        matcov[i][j]=x[i];
       printf("%3d",i);      }
       for(j=1; j<=i;j++){    }
         fprintf(ficres," %.5e",matcov[i][j]);  
         printf(" %.5e",matcov[i][j]);    printf("\n#Hessian matrix#\n");
       }    fprintf(ficlog,"\n#Hessian matrix#\n");
       fprintf(ficres,"\n");    for (i=1;i<=npar;i++) { 
       printf("\n");      for (j=1;j<=npar;j++) { 
       k++;        printf("%.3e ",hess[i][j]);
     }        fprintf(ficlog,"%.3e ",hess[i][j]);
          }
     while((c=getc(ficpar))=='#' && c!= EOF){      printf("\n");
       ungetc(c,ficpar);      fprintf(ficlog,"\n");
       fgets(line, MAXLINE, ficpar);    }
       puts(line);  
       fputs(line,ficparo);    /* Recompute Inverse */
     }    for (i=1;i<=npar;i++)
     ungetc(c,ficpar);      for (j=1;j<=npar;j++) a[i][j]=matcov[i][j];
      ludcmp(a,npar,indx,&pd);
     fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf\n",&agemin,&agemax, &bage, &fage);  
        /*  printf("\n#Hessian matrix recomputed#\n");
     if (fage <= 2) {  
       bage = agemin;    for (j=1;j<=npar;j++) {
       fage = agemax;      for (i=1;i<=npar;i++) x[i]=0;
     }      x[j]=1;
       lubksb(a,npar,indx,x);
     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");      for (i=1;i<=npar;i++){ 
     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f\n",agemin,agemax,bage,fage);        y[i][j]=x[i];
         printf("%.3e ",y[i][j]);
            fprintf(ficlog,"%.3e ",y[i][j]);
 /*------------ gnuplot -------------*/      }
 chdir(pathcd);      printf("\n");
   if((ficgp=fopen("graph.plt","w"))==NULL) {      fprintf(ficlog,"\n");
     printf("Problem with file graph.gp");goto end;    }
   }    */
 #ifdef windows  
   fprintf(ficgp,"cd \"%s\" \n",pathc);    free_matrix(a,1,npar,1,npar);
 #endif    free_matrix(y,1,npar,1,npar);
 m=pow(2,cptcoveff);    free_vector(x,1,npar);
      free_ivector(indx,1,npar);
  /* 1eme*/    free_matrix(hess,1,npar,1,npar);
   for (cpt=1; cpt<= nlstate ; cpt ++) {  
    for (k1=1; k1<= m ; k1 ++) {  
   }
 #ifdef windows  
     fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter gif small size 400,300\nplot [%.f:%.f] \"vpl%s\" every :::%d::%d u 1:2 \"\%%lf",agemin,fage,fileres,k1-1,k1-1);  /*************** hessian matrix ****************/
 #endif  double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
 #ifdef unix  {
 fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nplot [%.f:%.f] \"vpl%s\" u 1:2 \"\%%lf",agemin,fage,fileres);    int i;
 #endif    int l=1, lmax=20;
     double k1,k2;
 for (i=1; i<= nlstate ; i ++) {    double p2[MAXPARM+1]; /* identical to x */
   if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");    double res;
   else fprintf(ficgp," \%%*lf (\%%*lf)");    double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
 }    double fx;
     fprintf(ficgp,"\" t\"Stationary prevalence\" w l 0,\"vpl%s\" every :::%d::%d u 1:($2+2*$3) \"\%%lf",fileres,k1-1,k1-1);    int k=0,kmax=10;
     for (i=1; i<= nlstate ; i ++) {    double l1;
   if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");  
   else fprintf(ficgp," \%%*lf (\%%*lf)");    fx=func(x);
 }    for (i=1;i<=npar;i++) p2[i]=x[i];
   fprintf(ficgp,"\" t\"95\%% CI\" w l 1,\"vpl%s\" every :::%d::%d u 1:($2-2*$3) \"\%%lf",fileres,k1-1,k1-1);    for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
      for (i=1; i<= nlstate ; i ++) {      l1=pow(10,l);
   if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");      delts=delt;
   else fprintf(ficgp," \%%*lf (\%%*lf)");      for(k=1 ; k <kmax; k=k+1){
 }          delt = delta*(l1*k);
      fprintf(ficgp,"\" t\"\" w l 1,\"p%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence \" w l 2",fileres,k1-1,k1-1,2+4*(cpt-1));        p2[theta]=x[theta] +delt;
 #ifdef unix        k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
 fprintf(ficgp,"\nset ter gif small size 400,300");        p2[theta]=x[theta]-delt;
 #endif        k2=func(p2)-fx;
 fprintf(ficgp,"\nset out \"v%s%d%d.gif\" \nreplot\n\n",strtok(optionfile, "."),cpt,k1);        /*res= (k1-2.0*fx+k2)/delt/delt; */
    }        res= (k1+k2)/delt/delt/2.; /* Divided by because L and not 2*L */
   }        
   /*2 eme*/  #ifdef DEBUGHESS
         printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
   for (k1=1; k1<= m ; k1 ++) {        fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
     fprintf(ficgp,"set ylabel \"Years\" \nset ter gif small size 400,300\nplot [%.f:%.f] ",agemin,fage);  #endif
            /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
     for (i=1; i<= nlstate+1 ; i ++) {        if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
       k=2*i;          k=kmax;
       fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:2 \"\%%lf",fileres,k1-1,k1-1);        }
       for (j=1; j<= nlstate+1 ; j ++) {        else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
   if (j==i) fprintf(ficgp," \%%lf (\%%lf)");          k=kmax; l=lmax*10.;
   else fprintf(ficgp," \%%*lf (\%%*lf)");        }
 }          else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
       if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l ,");          delts=delt;
       else fprintf(ficgp,"\" t\"LE in state (%d)\" w l ,",i-1);        }
     fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:($2-$3*2) \"\%%lf",fileres,k1-1,k1-1);      }
       for (j=1; j<= nlstate+1 ; j ++) {    }
         if (j==i) fprintf(ficgp," \%%lf (\%%lf)");    delti[theta]=delts;
         else fprintf(ficgp," \%%*lf (\%%*lf)");    return res; 
 }      
       fprintf(ficgp,"\" t\"\" w l 0,");  }
      fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:($2+$3*2) \"\%%lf",fileres,k1-1,k1-1);  
       for (j=1; j<= nlstate+1 ; j ++) {  double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
   if (j==i) fprintf(ficgp," \%%lf (\%%lf)");  {
   else fprintf(ficgp," \%%*lf (\%%*lf)");    int i;
 }      int l=1, l1, lmax=20;
       if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l 0");    double k1,k2,k3,k4,res,fx;
       else fprintf(ficgp,"\" t\"\" w l 0,");    double p2[MAXPARM+1];
     }    int k;
     fprintf(ficgp,"\nset out \"e%s%d.gif\" \nreplot\n\n",strtok(optionfile, "."),k1);  
   }    fx=func(x);
      for (k=1; k<=2; k++) {
   /*3eme*/      for (i=1;i<=npar;i++) p2[i]=x[i];
       p2[thetai]=x[thetai]+delti[thetai]/k;
   for (k1=1; k1<= m ; k1 ++) {      p2[thetaj]=x[thetaj]+delti[thetaj]/k;
     for (cpt=1; cpt<= nlstate ; cpt ++) {      k1=func(p2)-fx;
       k=2+nlstate*(cpt-1);    
       fprintf(ficgp,"set ter gif small size 400,300\nplot [%.f:%.f] \"e%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",agemin,fage,fileres,k1-1,k1-1,k,cpt);      p2[thetai]=x[thetai]+delti[thetai]/k;
       for (i=1; i< nlstate ; i ++) {      p2[thetaj]=x[thetaj]-delti[thetaj]/k;
         fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",fileres,k1-1,k1-1,k+i,cpt,i+1);      k2=func(p2)-fx;
       }    
       fprintf(ficgp,"\nset out \"exp%s%d%d.gif\" \nreplot\n\n",strtok(optionfile, "."),cpt,k1);      p2[thetai]=x[thetai]-delti[thetai]/k;
     }      p2[thetaj]=x[thetaj]+delti[thetaj]/k;
   }      k3=func(p2)-fx;
      
   /* CV preval stat */      p2[thetai]=x[thetai]-delti[thetai]/k;
   for (k1=1; k1<= m ; k1 ++) {      p2[thetaj]=x[thetaj]-delti[thetaj]/k;
     for (cpt=1; cpt<nlstate ; cpt ++) {      k4=func(p2)-fx;
       k=3;      res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /* Because of L not 2*L */
       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter gif small size 400,300\nplot [%.f:%.f] \"pij%s\" u ($1==%d ? ($3):1/0):($%d/($%d",agemin,agemax,fileres,k1,k+cpt+1,k+1);  #ifdef DEBUG
       for (i=1; i< nlstate ; i ++)      printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
         fprintf(ficgp,"+$%d",k+i+1);      fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
       fprintf(ficgp,")) t\"prev(%d,%d)\" w l",cpt,cpt+1);  #endif
          }
       l=3+(nlstate+ndeath)*cpt;    return res;
       fprintf(ficgp,",\"pij%s\" u ($1==%d ? ($3):1/0):($%d/($%d",fileres,k1,l+cpt+1,l+1);  }
       for (i=1; i< nlstate ; i ++) {  
         l=3+(nlstate+ndeath)*cpt;  /************** Inverse of matrix **************/
         fprintf(ficgp,"+$%d",l+i+1);  void ludcmp(double **a, int n, int *indx, double *d) 
       }  { 
       fprintf(ficgp,")) t\"prev(%d,%d)\" w l\n",cpt+1,cpt+1);      int i,imax,j,k; 
       fprintf(ficgp,"set out \"p%s%d%d.gif\" \nreplot\n\n",strtok(optionfile, "."),cpt,k1);    double big,dum,sum,temp; 
     }    double *vv; 
   }   
     vv=vector(1,n); 
   /* proba elementaires */    *d=1.0; 
    for(i=1,jk=1; i <=nlstate; i++){    for (i=1;i<=n;i++) { 
     for(k=1; k <=(nlstate+ndeath); k++){      big=0.0; 
       if (k != i) {      for (j=1;j<=n;j++) 
         for(j=1; j <=ncovmodel; j++){        if ((temp=fabs(a[i][j])) > big) big=temp; 
           /*fprintf(ficgp,"%s%1d%1d=%f ",alph[j],i,k,p[jk]);*/      if (big == 0.0) nrerror("Singular matrix in routine ludcmp"); 
           /*fprintf(ficgp,"%s",alph[1]);*/      vv[i]=1.0/big; 
           fprintf(ficgp,"p%d=%f ",jk,p[jk]);    } 
           jk++;    for (j=1;j<=n;j++) { 
           fprintf(ficgp,"\n");      for (i=1;i<j;i++) { 
         }        sum=a[i][j]; 
       }        for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
     }        a[i][j]=sum; 
     }      } 
       big=0.0; 
   for(jk=1; jk <=m; jk++) {      for (i=j;i<=n;i++) { 
   fprintf(ficgp,"\nset ter gif small size 400,300\nset log y\nplot  [%.f:%.f] ",agemin,agemax);        sum=a[i][j]; 
    i=1;        for (k=1;k<j;k++) 
    for(k2=1; k2<=nlstate; k2++) {          sum -= a[i][k]*a[k][j]; 
      k3=i;        a[i][j]=sum; 
      for(k=1; k<=(nlstate+ndeath); k++) {        if ( (dum=vv[i]*fabs(sum)) >= big) { 
        if (k != k2){          big=dum; 
         fprintf(ficgp," exp(p%d+p%d*x",i,i+1);          imax=i; 
 ij=1;        } 
         for(j=3; j <=ncovmodel; j++) {      } 
           if(((j-2)==Tage[ij]) &&(ij <=cptcovage)) {      if (j != imax) { 
             fprintf(ficgp,"+p%d*%d*x",i+j-1,nbcode[Tvar[j-2]][codtab[jk][Tvar[j-2]]]);        for (k=1;k<=n;k++) { 
             ij++;          dum=a[imax][k]; 
           }          a[imax][k]=a[j][k]; 
           else          a[j][k]=dum; 
           fprintf(ficgp,"+p%d*%d",i+j-1,nbcode[Tvar[j-2]][codtab[jk][j-2]]);        } 
         }        *d = -(*d); 
           fprintf(ficgp,")/(1");        vv[imax]=vv[j]; 
              } 
         for(k1=1; k1 <=nlstate; k1++){        indx[j]=imax; 
           fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);      if (a[j][j] == 0.0) a[j][j]=TINY; 
 ij=1;      if (j != n) { 
           for(j=3; j <=ncovmodel; j++){        dum=1.0/(a[j][j]); 
           if(((j-2)==Tage[ij]) &&(ij <=cptcovage)) {        for (i=j+1;i<=n;i++) a[i][j] *= dum; 
             fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2,nbcode[Tvar[j-2]][codtab[jk][Tvar[j-2]]]);      } 
             ij++;    } 
           }    free_vector(vv,1,n);  /* Doesn't work */
           else  ;
             fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2,nbcode[Tvar[j-2]][codtab[jk][j-2]]);  } 
           }  
           fprintf(ficgp,")");  void lubksb(double **a, int n, int *indx, double b[]) 
         }  { 
         fprintf(ficgp,") t \"p%d%d\" ", k2,k);    int i,ii=0,ip,j; 
         if ((k+k2)!= (nlstate*2+ndeath)) fprintf(ficgp,",");    double sum; 
         i=i+ncovmodel;   
        }    for (i=1;i<=n;i++) { 
      }      ip=indx[i]; 
    }      sum=b[ip]; 
    fprintf(ficgp,"\nset out \"pe%s%d.gif\" \nreplot\n\n",strtok(optionfile, "."),jk);      b[ip]=b[i]; 
   }      if (ii) 
            for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
   fclose(ficgp);      else if (sum) ii=i; 
          b[i]=sum; 
 chdir(path);    } 
     free_matrix(agev,1,maxwav,1,imx);    for (i=n;i>=1;i--) { 
     free_ivector(wav,1,imx);      sum=b[i]; 
     free_imatrix(dh,1,lastpass-firstpass+1,1,imx);      for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
     free_imatrix(mw,1,lastpass-firstpass+1,1,imx);      b[i]=sum/a[i][i]; 
        } 
     free_imatrix(s,1,maxwav+1,1,n);  } 
      
      void pstamp(FILE *fichier)
     free_ivector(num,1,n);  {
     free_vector(agedc,1,n);    fprintf(fichier,"# %s.%s\n#%s\n#%s\n# %s", optionfilefiname,optionfilext,version,fullversion,strstart);
     free_vector(weight,1,n);  }
     /*free_matrix(covar,1,NCOVMAX,1,n);*/  
     fclose(ficparo);  /************ Frequencies ********************/
     fclose(ficres);  void  freqsummary(char fileres[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, int *Tvaraff, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[])
     /*  }*/  {  /* Some frequencies */
        
    /*________fin mle=1_________*/    int i, m, jk, k1,i1, j1, bool, z1,j;
        int first;
     double ***freq; /* Frequencies */
      double *pp, **prop;
     /* No more information from the sample is required now */    double pos,posprop, k2, dateintsum=0,k2cpt=0;
   /* Reads comments: lines beginning with '#' */    char fileresp[FILENAMELENGTH];
   while((c=getc(ficpar))=='#' && c!= EOF){    
     ungetc(c,ficpar);    pp=vector(1,nlstate);
     fgets(line, MAXLINE, ficpar);    prop=matrix(1,nlstate,iagemin,iagemax+3);
     puts(line);    strcpy(fileresp,"p");
     fputs(line,ficparo);    strcat(fileresp,fileres);
   }    if((ficresp=fopen(fileresp,"w"))==NULL) {
   ungetc(c,ficpar);      printf("Problem with prevalence resultfile: %s\n", fileresp);
        fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
   fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf\n",&agemin,&agemax, &bage, &fage);      exit(0);
   printf("agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f\n",agemin,agemax, bage, fage);    }
   fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f\n",agemin,agemax,bage,fage);    freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin,iagemax+3);
 /*--------- index.htm --------*/    j1=0;
     
   if((fichtm=fopen("index.htm","w"))==NULL)    {    j=cptcoveff;
     printf("Problem with index.htm \n");goto end;    if (cptcovn<1) {j=1;ncodemax[1]=1;}
   }  
     first=1;
  fprintf(fichtm,"<body><ul> <font size=\"6\">Imach, Version 0.64a </font> <hr size=\"2\" color=\"#EC5E5E\">  
 Titre=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=%s<br>    /* for(k1=1; k1<=j ; k1++){   /* Loop on covariates */
 Total number of observations=%d <br>    /*  for(i1=1; i1<=ncodemax[k1];i1++){ /* Now it is 2 */
 Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>    /*    j1++;
 <hr  size=\"2\" color=\"#EC5E5E\">  */
 <li>Outputs files<br><br>\n    for (j1 = 1; j1 <= (int) pow(2,cptcoveff); j1++){
         - Observed prevalence in each state: <a href=\"p%s\">p%s</a> <br>\n        /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
 - Estimated parameters and the covariance matrix: <a href=\"%s\">%s</a> <br>          scanf("%d", i);*/
         - Stationary prevalence in each state: <a href=\"pl%s\">pl%s</a> <br>        for (i=-5; i<=nlstate+ndeath; i++)  
         - Transition probabilities: <a href=\"pij%s\">pij%s</a><br>          for (jk=-5; jk<=nlstate+ndeath; jk++)  
         - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>            for(m=iagemin; m <= iagemax+3; m++)
         - Life expectancies by age and initial health status: <a href=\"e%s\">e%s</a> <br>              freq[i][jk][m]=0;
         - Variances of life expectancies by age and initial health status: <a href=\"v%s\">v%s</a><br>        
         - Health expectancies with their variances: <a href=\"t%s\">t%s</a> <br>        for (i=1; i<=nlstate; i++)  
         - Standard deviation of stationary prevalences: <a href=\"vpl%s\">vpl%s</a> <br><br>",title,datafile,firstpass,lastpass,stepm, weightopt,model,imx,jmin,jmax,jmean,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres);          for(m=iagemin; m <= iagemax+3; m++)
             prop[i][m]=0;
  fprintf(fichtm," <li>Graphs</li><p>");        
         dateintsum=0;
  m=cptcoveff;        k2cpt=0;
  if (cptcovn < 1) {m=1;ncodemax[1]=1;}        for (i=1; i<=imx; i++) {
           bool=1;
  j1=0;          if  (cptcovn>0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
  for(k1=1; k1<=m;k1++){            for (z1=1; z1<=cptcoveff; z1++)       
    for(i1=1; i1<=ncodemax[k1];i1++){              if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtab[j1][z1]]){
        j1++;                  /* Tests if the value of each of the covariates of i is equal to filter j1 */
        if (cptcovn > 0) {                bool=0;
          fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");                /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtab[%d][%d]=%d, nbcode[Tvaraff][codtab[%d][%d]=%d, j1=%d\n", 
          for (cpt=1; cpt<=cptcoveff;cpt++)                  bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtab[j1][z1],
            fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtab[j1][cpt]]);                  j1,z1,nbcode[Tvaraff[z1]][codtab[j1][z1]],j1);*/
          fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");                /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtab[7][3]=1 and nbcde[3][?]=1*/
        }              } 
        fprintf(fichtm,"<br>- Probabilities: pe%s%d.gif<br>          }
 <img src=\"pe%s%d.gif\">",strtok(optionfile, "."),j1,strtok(optionfile, "."),j1);       
        for(cpt=1; cpt<nlstate;cpt++){          if (bool==1){
          fprintf(fichtm,"<br>- Prevalence of disability : p%s%d%d.gif<br>            for(m=firstpass; m<=lastpass; m++){
 <img src=\"p%s%d%d.gif\">",strtok(optionfile, "."),cpt,j1,strtok(optionfile, "."),cpt,j1);              k2=anint[m][i]+(mint[m][i]/12.);
        }              /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
     for(cpt=1; cpt<=nlstate;cpt++) {                if(agev[m][i]==0) agev[m][i]=iagemax+1;
        fprintf(fichtm,"<br>- Observed and stationary prevalence (with confident                if(agev[m][i]==1) agev[m][i]=iagemax+2;
 interval) in state (%d): v%s%d%d.gif <br>                if (s[m][i]>0 && s[m][i]<=nlstate) prop[s[m][i]][(int)agev[m][i]] += weight[i];
 <img src=\"v%s%d%d.gif\">",cpt,strtok(optionfile, "."),cpt,j1,strtok(optionfile, "."),cpt,j1);                  if (m<lastpass) {
      }                  freq[s[m][i]][s[m+1][i]][(int)agev[m][i]] += weight[i];
      for(cpt=1; cpt<=nlstate;cpt++) {                  freq[s[m][i]][s[m+1][i]][iagemax+3] += weight[i];
         fprintf(fichtm,"\n<br>- Health life expectancies by age and initial health state (%d): exp%s%d%d.gif <br>                }
 <img src=\"exp%s%d%d.gif\">",cpt,strtok(optionfile, "."),cpt,j1,strtok(optionfile, "."),cpt,j1);                
      }                if ((agev[m][i]>1) && (agev[m][i]< (iagemax+3))) {
      fprintf(fichtm,"\n<br>- Total life expectancy by age and                  dateintsum=dateintsum+k2;
 health expectancies in states (1) and (2): e%s%d.gif<br>                  k2cpt++;
 <img src=\"e%s%d.gif\">",strtok(optionfile, "."),j1,strtok(optionfile, "."),j1);                }
 fprintf(fichtm,"\n</body>");                /*}*/
    }            }
  }          }
 fclose(fichtm);        } /* end i */
          
   /*--------------- Prevalence limit --------------*/        /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
          pstamp(ficresp);
   strcpy(filerespl,"pl");        if  (cptcovn>0) {
   strcat(filerespl,fileres);          fprintf(ficresp, "\n#********** Variable "); 
   if((ficrespl=fopen(filerespl,"w"))==NULL) {          for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
     printf("Problem with Prev limit resultfile: %s\n", filerespl);goto end;          fprintf(ficresp, "**********\n#");
   }          fprintf(ficlog, "\n#********** Variable "); 
   printf("Computing prevalence limit: result on file '%s' \n", filerespl);          for (z1=1; z1<=cptcoveff; z1++) fprintf(ficlog, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
   fprintf(ficrespl,"#Prevalence limit\n");          fprintf(ficlog, "**********\n#");
   fprintf(ficrespl,"#Age ");        }
   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);        for(i=1; i<=nlstate;i++) 
   fprintf(ficrespl,"\n");          fprintf(ficresp, " Age Prev(%d) N(%d) N",i,i);
          fprintf(ficresp, "\n");
   prlim=matrix(1,nlstate,1,nlstate);        
   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */        for(i=iagemin; i <= iagemax+3; i++){
   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */          if(i==iagemax+3){
   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */            fprintf(ficlog,"Total");
   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */          }else{
   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */            if(first==1){
   k=0;              first=0;
   agebase=agemin;              printf("See log file for details...\n");
   agelim=agemax;            }
   ftolpl=1.e-10;            fprintf(ficlog,"Age %d", i);
   i1=cptcoveff;          }
   if (cptcovn < 1){i1=1;}          for(jk=1; jk <=nlstate ; jk++){
             for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
   for(cptcov=1;cptcov<=i1;cptcov++){              pp[jk] += freq[jk][m][i]; 
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){          }
         k=k+1;          for(jk=1; jk <=nlstate ; jk++){
         /*printf("cptcov=%d cptcod=%d codtab=%d nbcode=%d\n",cptcov, cptcod,Tcode[cptcode],codtab[cptcod][cptcov]);*/            for(m=-1, pos=0; m <=0 ; m++)
         fprintf(ficrespl,"\n#******");              pos += freq[jk][m][i];
         for(j=1;j<=cptcoveff;j++)            if(pp[jk]>=1.e-10){
           fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);              if(first==1){
         fprintf(ficrespl,"******\n");                printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                      }
         for (age=agebase; age<=agelim; age++){              fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
           prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);            }else{
           fprintf(ficrespl,"%.0f",age );              if(first==1)
           for(i=1; i<=nlstate;i++)                printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
           fprintf(ficrespl," %.5f", prlim[i][i]);              fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
           fprintf(ficrespl,"\n");            }
         }          }
       }  
     }          for(jk=1; jk <=nlstate ; jk++){
   fclose(ficrespl);            for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)
   /*------------- h Pij x at various ages ------------*/              pp[jk] += freq[jk][m][i];
            }       
   strcpy(filerespij,"pij");  strcat(filerespij,fileres);          for(jk=1,pos=0,posprop=0; jk <=nlstate ; jk++){
   if((ficrespij=fopen(filerespij,"w"))==NULL) {            pos += pp[jk];
     printf("Problem with Pij resultfile: %s\n", filerespij);goto end;            posprop += prop[jk][i];
   }          }
   printf("Computing pij: result on file '%s' \n", filerespij);          for(jk=1; jk <=nlstate ; jk++){
              if(pos>=1.e-5){
   stepsize=(int) (stepm+YEARM-1)/YEARM;              if(first==1)
   if (stepm<=24) stepsize=2;                printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
               fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
   agelim=AGESUP;            }else{
   hstepm=stepsize*YEARM; /* Every year of age */              if(first==1)
   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */                printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
   k=0;            }
   for(cptcov=1;cptcov<=i1;cptcov++){            if( i <= iagemax){
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){              if(pos>=1.e-5){
       k=k+1;                fprintf(ficresp," %d %.5f %.0f %.0f",i,prop[jk][i]/posprop, prop[jk][i],posprop);
         fprintf(ficrespij,"\n#****** ");                /*probs[i][jk][j1]= pp[jk]/pos;*/
         for(j=1;j<=cptcoveff;j++)                /*printf("\ni=%d jk=%d j1=%d %.5f %.0f %.0f %f",i,jk,j1,pp[jk]/pos, pp[jk],pos,probs[i][jk][j1]);*/
           fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);              }
         fprintf(ficrespij,"******\n");              else
                        fprintf(ficresp," %d NaNq %.0f %.0f",i,prop[jk][i],posprop);
         for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */            }
           nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */          }
           nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */          
           p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);          for(jk=-1; jk <=nlstate+ndeath; jk++)
           oldm=oldms;savm=savms;            for(m=-1; m <=nlstate+ndeath; m++)
           hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);                if(freq[jk][m][i] !=0 ) {
           fprintf(ficrespij,"# Age");              if(first==1)
           for(i=1; i<=nlstate;i++)                printf(" %d%d=%.0f",jk,m,freq[jk][m][i]);
             for(j=1; j<=nlstate+ndeath;j++)                fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][i]);
               fprintf(ficrespij," %1d-%1d",i,j);              }
           fprintf(ficrespij,"\n");          if(i <= iagemax)
           for (h=0; h<=nhstepm; h++){            fprintf(ficresp,"\n");
             fprintf(ficrespij,"%d %.0f %.0f",k,agedeb, agedeb+ h*hstepm/YEARM*stepm );          if(first==1)
             for(i=1; i<=nlstate;i++)            printf("Others in log...\n");
               for(j=1; j<=nlstate+ndeath;j++)          fprintf(ficlog,"\n");
                 fprintf(ficrespij," %.5f", p3mat[i][j][h]);        }
             fprintf(ficrespij,"\n");        /*}*/
           }    }
           free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);    dateintmean=dateintsum/k2cpt; 
           fprintf(ficrespij,"\n");   
         }    fclose(ficresp);
     }    free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin, iagemax+3);
   }    free_vector(pp,1,nlstate);
     free_matrix(prop,1,nlstate,iagemin, iagemax+3);
   fclose(ficrespij);    /* End of Freq */
   }
   /*---------- Health expectancies and variances ------------*/  
   /************ Prevalence ********************/
   strcpy(filerest,"t");  void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
   strcat(filerest,fileres);  {  
   if((ficrest=fopen(filerest,"w"))==NULL) {    /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
     printf("Problem with total LE resultfile: %s\n", filerest);goto end;       in each health status at the date of interview (if between dateprev1 and dateprev2).
   }       We still use firstpass and lastpass as another selection.
   printf("Computing Total LEs with variances: file '%s' \n", filerest);    */
    
     int i, m, jk, k1, i1, j1, bool, z1,j;
   strcpy(filerese,"e");    double ***freq; /* Frequencies */
   strcat(filerese,fileres);    double *pp, **prop;
   if((ficreseij=fopen(filerese,"w"))==NULL) {    double pos,posprop; 
     printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);    double  y2; /* in fractional years */
   }    int iagemin, iagemax;
   printf("Computing Health Expectancies: result on file '%s' \n", filerese);    int first; /** to stop verbosity which is redirected to log file */
   
  strcpy(fileresv,"v");    iagemin= (int) agemin;
   strcat(fileresv,fileres);    iagemax= (int) agemax;
   if((ficresvij=fopen(fileresv,"w"))==NULL) {    /*pp=vector(1,nlstate);*/
     printf("Problem with variance resultfile: %s\n", fileresv);exit(0);    prop=matrix(1,nlstate,iagemin,iagemax+3); 
   }    /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
   printf("Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);    j1=0;
     
   k=0;    /*j=cptcoveff;*/
   for(cptcov=1;cptcov<=i1;cptcov++){    if (cptcovn<1) {j=1;ncodemax[1]=1;}
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){    
       k=k+1;    first=1;
       fprintf(ficrest,"\n#****** ");    for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){
       for(j=1;j<=cptcoveff;j++)      /*for(i1=1; i1<=ncodemax[k1];i1++){
         fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);        j1++;*/
       fprintf(ficrest,"******\n");        
         for (i=1; i<=nlstate; i++)  
       fprintf(ficreseij,"\n#****** ");          for(m=iagemin; m <= iagemax+3; m++)
       for(j=1;j<=cptcoveff;j++)            prop[i][m]=0.0;
         fprintf(ficreseij,"V%d=%d ",j,nbcode[j][codtab[k][j]]);       
       fprintf(ficreseij,"******\n");        for (i=1; i<=imx; i++) { /* Each individual */
           bool=1;
       fprintf(ficresvij,"\n#****** ");          if  (cptcovn>0) {
       for(j=1;j<=cptcoveff;j++)            for (z1=1; z1<=cptcoveff; z1++) 
         fprintf(ficresvij,"V%d=%d ",j,nbcode[j][codtab[k][j]]);              if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtab[j1][z1]]) 
       fprintf(ficresvij,"******\n");                bool=0;
           } 
       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);          if (bool==1) { 
       oldm=oldms;savm=savms;            for(m=firstpass; m<=lastpass; m++){/* Other selection (we can limit to certain interviews*/
       evsij(fileres, eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k);                y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);              if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
       oldm=oldms;savm=savms;                if(agev[m][i]==0) agev[m][i]=iagemax+1;
       varevsij(fileres, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k);                if(agev[m][i]==1) agev[m][i]=iagemax+2;
                      if((int)agev[m][i] <iagemin || (int)agev[m][i] >iagemax+3) printf("Error on individual =%d agev[m][i]=%f m=%d\n",i, agev[m][i],m); 
       fprintf(ficrest,"#Total LEs with variances: e.. (std) ");                if (s[m][i]>0 && s[m][i]<=nlstate) { 
       for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);                  /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
       fprintf(ficrest,"\n");                  prop[s[m][i]][(int)agev[m][i]] += weight[i];
                          prop[s[m][i]][iagemax+3] += weight[i]; 
       hf=1;                } 
       if (stepm >= YEARM) hf=stepm/YEARM;              }
       epj=vector(1,nlstate+1);            } /* end selection of waves */
       for(age=bage; age <=fage ;age++){          }
         prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);        }
         fprintf(ficrest," %.0f",age);        for(i=iagemin; i <= iagemax+3; i++){  
         for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){          for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
           for(i=1, epj[j]=0.;i <=nlstate;i++) {            posprop += prop[jk][i]; 
             epj[j] += prlim[i][i]*hf*eij[i][j][(int)age];          } 
           }          
           epj[nlstate+1] +=epj[j];          for(jk=1; jk <=nlstate ; jk++){     
         }            if( i <=  iagemax){ 
         for(i=1, vepp=0.;i <=nlstate;i++)              if(posprop>=1.e-5){ 
           for(j=1;j <=nlstate;j++)                probs[i][jk][j1]= prop[jk][i]/posprop;
             vepp += vareij[i][j][(int)age];              } else{
         fprintf(ficrest," %.2f (%.2f)", epj[nlstate+1],hf*sqrt(vepp));                if(first==1){
         for(j=1;j <=nlstate;j++){                  first=0;
           fprintf(ficrest," %.2f (%.2f)", epj[j],hf*sqrt(vareij[j][j][(int)age]));                  printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others on log file...\n",jk,i,j1,probs[i][jk][j1]);
         }                }
         fprintf(ficrest,"\n");              }
       }            } 
     }          }/* end jk */ 
   }        }/* end i */ 
              /*} *//* end i1 */
  fclose(ficreseij);    } /* end j1 */
  fclose(ficresvij);    
   fclose(ficrest);    /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
   fclose(ficpar);    /*free_vector(pp,1,nlstate);*/
   free_vector(epj,1,nlstate+1);    free_matrix(prop,1,nlstate, iagemin,iagemax+3);
   /*  scanf("%d ",i); */  }  /* End of prevalence */
   
   /*------- Variance limit prevalence------*/    /************* Waves Concatenation ***************/
   
 strcpy(fileresvpl,"vpl");  void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
   strcat(fileresvpl,fileres);  {
   if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {    /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
     printf("Problem with variance prev lim resultfile: %s\n", fileresvpl);       Death is a valid wave (if date is known).
     exit(0);       mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
   }       dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
   printf("Computing Variance-covariance of Prevalence limit: file '%s' \n", fileresvpl);       and mw[mi+1][i]. dh depends on stepm.
        */
  k=0;  
  for(cptcov=1;cptcov<=i1;cptcov++){    int i, mi, m;
    for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){    /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
      k=k+1;       double sum=0., jmean=0.;*/
      fprintf(ficresvpl,"\n#****** ");    int first;
      for(j=1;j<=cptcoveff;j++)    int j, k=0,jk, ju, jl;
        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);    double sum=0.;
      fprintf(ficresvpl,"******\n");    first=0;
          jmin=1e+5;
      varpl=matrix(1,nlstate,(int) bage, (int) fage);    jmax=-1;
      oldm=oldms;savm=savms;    jmean=0.;
      varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k);    for(i=1; i<=imx; i++){
    }      mi=0;
  }      m=firstpass;
       while(s[m][i] <= nlstate){
   fclose(ficresvpl);        if(s[m][i]>=1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5)
           mw[++mi][i]=m;
   /*---------- End : free ----------------*/        if(m >=lastpass)
   free_matrix(varpl,1,nlstate,(int) bage, (int)fage);          break;
          else
   free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);          m++;
   free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);      }/* end while */
        if (s[m][i] > nlstate){
          mi++;     /* Death is another wave */
   free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);        /* if(mi==0)  never been interviewed correctly before death */
   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);           /* Only death is a correct wave */
   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);        mw[mi][i]=m;
   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);      }
    
   free_matrix(matcov,1,npar,1,npar);      wav[i]=mi;
   free_vector(delti,1,npar);      if(mi==0){
          nbwarn++;
   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);        if(first==0){
           printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
   printf("End of Imach\n");          first=1;
   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */        }
          if(first==1){
   /* printf("Total time was %d Sec. %d uSec.\n", end_time.tv_sec -start_time.tv_sec, end_time.tv_usec -start_time.tv_usec);*/          fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
   /*printf("Total time was %d uSec.\n", total_usecs);*/        }
   /*------ End -----------*/      } /* end mi==0 */
     } /* End individuals */
  end:  
 #ifdef windows    for(i=1; i<=imx; i++){
  chdir(pathcd);      for(mi=1; mi<wav[i];mi++){
 #endif        if (stepm <=0)
  /*system("wgnuplot graph.plt");*/          dh[mi][i]=1;
  system("../gp37mgw/wgnuplot graph.plt");        else{
           if (s[mw[mi+1][i]][i] > nlstate) { /* A death */
 #ifdef windows            if (agedc[i] < 2*AGESUP) {
   while (z[0] != 'q') {              j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
     chdir(pathcd);              if(j==0) j=1;  /* Survives at least one month after exam */
     printf("\nType e to edit output files, c to start again, and q for exiting: ");              else if(j<0){
     scanf("%s",z);                nberr++;
     if (z[0] == 'c') system("./imach");                printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
     else if (z[0] == 'e') {                j=1; /* Temporary Dangerous patch */
       chdir(path);                printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
       system("index.htm");                fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
     }                fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
     else if (z[0] == 'q') exit(0);              }
   }              k=k+1;
 #endif              if (j >= jmax){
 }                jmax=j;
                 ijmax=i;
               }
               if (j <= jmin){
                 jmin=j;
                 ijmin=i;
               }
               sum=sum+j;
               /*if (j<0) printf("j=%d num=%d \n",j,i);*/
               /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
             }
           }
           else{
             j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
   /*        if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
   
             k=k+1;
             if (j >= jmax) {
               jmax=j;
               ijmax=i;
             }
             else if (j <= jmin){
               jmin=j;
               ijmin=i;
             }
             /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
             /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
             if(j<0){
               nberr++;
               printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
               fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
             }
             sum=sum+j;
           }
           jk= j/stepm;
           jl= j -jk*stepm;
           ju= j -(jk+1)*stepm;
           if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
             if(jl==0){
               dh[mi][i]=jk;
               bh[mi][i]=0;
             }else{ /* We want a negative bias in order to only have interpolation ie
                     * to avoid the price of an extra matrix product in likelihood */
               dh[mi][i]=jk+1;
               bh[mi][i]=ju;
             }
           }else{
             if(jl <= -ju){
               dh[mi][i]=jk;
               bh[mi][i]=jl;       /* bias is positive if real duration
                                    * is higher than the multiple of stepm and negative otherwise.
                                    */
             }
             else{
               dh[mi][i]=jk+1;
               bh[mi][i]=ju;
             }
             if(dh[mi][i]==0){
               dh[mi][i]=1; /* At least one step */
               bh[mi][i]=ju; /* At least one step */
               /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
             }
           } /* end if mle */
         }
       } /* end wave */
     }
     jmean=sum/k;
     printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
     fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
    }
   
   /*********** Tricode ****************************/
   void tricode(int *Tvar, int **nbcode, int imx, int *Ndum)
   {
     /**< Uses cptcovn+2*cptcovprod as the number of covariates */
     /*      Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
     /* Boring subroutine which should only output nbcode[Tvar[j]][k]
      * Tvar[5] in V2+V1+V3*age+V2*V4 is 2 (V2)
     /* nbcode[Tvar[j]][1]= 
     */
   
     int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
     int modmaxcovj=0; /* Modality max of covariates j */
     int cptcode=0; /* Modality max of covariates j */
     int modmincovj=0; /* Modality min of covariates j */
   
   
     cptcoveff=0; 
    
     for (k=-1; k < maxncov; k++) Ndum[k]=0;
     for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
   
     /* Loop on covariates without age and products */
     for (j=1; j<=(cptcovs); j++) { /* model V1 + V2*age+ V3 + V3*V4 : V1 + V3 = 2 only */
       for (i=1; i<=imx; i++) { /* Lopp on individuals: reads the data file to get the maximum value of the 
                                  modality of this covariate Vj*/ 
         ij=(int)(covar[Tvar[j]][i]); /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                                       * If product of Vn*Vm, still boolean *:
                                       * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                                       * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
         /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                                         modality of the nth covariate of individual i. */
         if (ij > modmaxcovj)
           modmaxcovj=ij; 
         else if (ij < modmincovj) 
           modmincovj=ij; 
         if ((ij < -1) && (ij > NCOVMAX)){
           printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
           exit(1);
         }else
         Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
         /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
         /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
         /* getting the maximum value of the modality of the covariate
            (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
            female is 1, then modmaxcovj=1.*/
       }
       printf(" Minimal and maximal values of %d th covariate V%d: min=%d max=%d \n", j, Tvar[j], modmincovj, modmaxcovj);
       cptcode=modmaxcovj;
       /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
      /*for (i=0; i<=cptcode; i++) {*/
       for (i=modmincovj;  i<=modmaxcovj; i++) { /* i=-1 ? 0 and 1*//* For each value of the modality of model-cov j */
         printf("Frequencies of covariates %d V%d %d\n", j, Tvar[j], Ndum[i]);
         if( Ndum[i] != 0 ){ /* Counts if nobody answered, empty modality */
           ncodemax[j]++;  /* ncodemax[j]= Number of non-null modalities of the j th covariate. */
         }
         /* In fact  ncodemax[j]=2 (dichotom. variables only) but it could be more for
            historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
       } /* Ndum[-1] number of undefined modalities */
   
       /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
       /* For covariate j, modalities could be 1, 2, 3, 4. If Ndum[2]=0 ncodemax[j] is not 4 but 3 */
       /* If Ndum[3}= 635; Ndum[4]=0; Ndum[5]=0; Ndum[6]=27; Ndum[7]=125;
          modmincovj=3; modmaxcovj = 7;
          There are only 3 modalities non empty (or 2 if 27 is too few) : ncodemax[j]=3;
          which will be coded 0, 1, 2 which in binary on 3-1 digits are 0=00 1=01, 2=10; defining two dummy 
          variables V1_1 and V1_2.
          nbcode[Tvar[j]][ij]=k;
          nbcode[Tvar[j]][1]=0;
          nbcode[Tvar[j]][2]=1;
          nbcode[Tvar[j]][3]=2;
       */
       ij=1; /* ij is similar to i but can jumps over null modalities */
       for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 */
         for (k=0; k<= cptcode; k++) { /* k=-1 ? k=0 to 1 *//* Could be 1 to 4 */
           /*recode from 0 */
           if (Ndum[k] != 0) { /* If at least one individual responded to this modality k */
             nbcode[Tvar[j]][ij]=k;  /* stores the modality in an array nbcode. 
                                        k is a modality. If we have model=V1+V1*sex 
                                        then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
             ij++;
           }
           if (ij > ncodemax[j]) break; 
         }  /* end of loop on */
       } /* end of loop on modality */ 
     } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
     
    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
     
     for (i=1; i<=ncovmodel-2; i++) { /* -2, cste and age */ 
      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
      ij=Tvar[i]; /* Tvar might be -1 if status was unknown */ 
      Ndum[ij]++; 
    } 
   
    ij=1;
    for (i=0; i<=  maxncov-1; i++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
      if((Ndum[i]!=0) && (i<=ncovcol)){
        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
        Tvaraff[ij]=i; /*For printing (unclear) */
        ij++;
      }else
          Tvaraff[ij]=0;
    }
    ij--;
    cptcoveff=ij; /*Number of total covariates*/
   
   }
   
   
   /*********** Health Expectancies ****************/
   
   void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[] )
   
   {
     /* Health expectancies, no variances */
     int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2;
     int nhstepma, nstepma; /* Decreasing with age */
     double age, agelim, hf;
     double ***p3mat;
     double eip;
   
     pstamp(ficreseij);
     fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
     fprintf(ficreseij,"# Age");
     for(i=1; i<=nlstate;i++){
       for(j=1; j<=nlstate;j++){
         fprintf(ficreseij," e%1d%1d ",i,j);
       }
       fprintf(ficreseij," e%1d. ",i);
     }
     fprintf(ficreseij,"\n");
   
     
     if(estepm < stepm){
       printf ("Problem %d lower than %d\n",estepm, stepm);
     }
     else  hstepm=estepm;   
     /* We compute the life expectancy from trapezoids spaced every estepm months
      * This is mainly to measure the difference between two models: for example
      * if stepm=24 months pijx are given only every 2 years and by summing them
      * we are calculating an estimate of the Life Expectancy assuming a linear 
      * progression in between and thus overestimating or underestimating according
      * to the curvature of the survival function. If, for the same date, we 
      * estimate the model with stepm=1 month, we can keep estepm to 24 months
      * to compare the new estimate of Life expectancy with the same linear 
      * hypothesis. A more precise result, taking into account a more precise
      * curvature will be obtained if estepm is as small as stepm. */
   
     /* For example we decided to compute the life expectancy with the smallest unit */
     /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
        nhstepm is the number of hstepm from age to agelim 
        nstepm is the number of stepm from age to agelin. 
        Look at hpijx to understand the reason of that which relies in memory size
        and note for a fixed period like estepm months */
     /* We decided (b) to get a life expectancy respecting the most precise curvature of the
        survival function given by stepm (the optimization length). Unfortunately it
        means that if the survival funtion is printed only each two years of age and if
        you sum them up and add 1 year (area under the trapezoids) you won't get the same 
        results. So we changed our mind and took the option of the best precision.
     */
     hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
   
     agelim=AGESUP;
     /* If stepm=6 months */
       /* Computed by stepm unit matrices, product of hstepm matrices, stored
          in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
       
   /* nhstepm age range expressed in number of stepm */
     nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
     /* if (stepm >= YEARM) hstepm=1;*/
     nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
   
     for (age=bage; age<=fage; age ++){ 
       nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
       /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
       /* if (stepm >= YEARM) hstepm=1;*/
       nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
   
       /* If stepm=6 months */
       /* Computed by stepm unit matrices, product of hstepma matrices, stored
          in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
       
       hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij);  
       
       hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
       
       printf("%d|",(int)age);fflush(stdout);
       fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
       
       /* Computing expectancies */
       for(i=1; i<=nlstate;i++)
         for(j=1; j<=nlstate;j++)
           for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
             eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
             
             /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
   
           }
   
       fprintf(ficreseij,"%3.0f",age );
       for(i=1; i<=nlstate;i++){
         eip=0;
         for(j=1; j<=nlstate;j++){
           eip +=eij[i][j][(int)age];
           fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
         }
         fprintf(ficreseij,"%9.4f", eip );
       }
       fprintf(ficreseij,"\n");
       
     }
     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     printf("\n");
     fprintf(ficlog,"\n");
     
   }
   
   void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[] )
   
   {
     /* Covariances of health expectancies eij and of total life expectancies according
      to initial status i, ei. .
     */
     int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
     int nhstepma, nstepma; /* Decreasing with age */
     double age, agelim, hf;
     double ***p3matp, ***p3matm, ***varhe;
     double **dnewm,**doldm;
     double *xp, *xm;
     double **gp, **gm;
     double ***gradg, ***trgradg;
     int theta;
   
     double eip, vip;
   
     varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
     xp=vector(1,npar);
     xm=vector(1,npar);
     dnewm=matrix(1,nlstate*nlstate,1,npar);
     doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
     
     pstamp(ficresstdeij);
     fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
     fprintf(ficresstdeij,"# Age");
     for(i=1; i<=nlstate;i++){
       for(j=1; j<=nlstate;j++)
         fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
       fprintf(ficresstdeij," e%1d. ",i);
     }
     fprintf(ficresstdeij,"\n");
   
     pstamp(ficrescveij);
     fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
     fprintf(ficrescveij,"# Age");
     for(i=1; i<=nlstate;i++)
       for(j=1; j<=nlstate;j++){
         cptj= (j-1)*nlstate+i;
         for(i2=1; i2<=nlstate;i2++)
           for(j2=1; j2<=nlstate;j2++){
             cptj2= (j2-1)*nlstate+i2;
             if(cptj2 <= cptj)
               fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
           }
       }
     fprintf(ficrescveij,"\n");
     
     if(estepm < stepm){
       printf ("Problem %d lower than %d\n",estepm, stepm);
     }
     else  hstepm=estepm;   
     /* We compute the life expectancy from trapezoids spaced every estepm months
      * This is mainly to measure the difference between two models: for example
      * if stepm=24 months pijx are given only every 2 years and by summing them
      * we are calculating an estimate of the Life Expectancy assuming a linear 
      * progression in between and thus overestimating or underestimating according
      * to the curvature of the survival function. If, for the same date, we 
      * estimate the model with stepm=1 month, we can keep estepm to 24 months
      * to compare the new estimate of Life expectancy with the same linear 
      * hypothesis. A more precise result, taking into account a more precise
      * curvature will be obtained if estepm is as small as stepm. */
   
     /* For example we decided to compute the life expectancy with the smallest unit */
     /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
        nhstepm is the number of hstepm from age to agelim 
        nstepm is the number of stepm from age to agelin. 
        Look at hpijx to understand the reason of that which relies in memory size
        and note for a fixed period like estepm months */
     /* We decided (b) to get a life expectancy respecting the most precise curvature of the
        survival function given by stepm (the optimization length). Unfortunately it
        means that if the survival funtion is printed only each two years of age and if
        you sum them up and add 1 year (area under the trapezoids) you won't get the same 
        results. So we changed our mind and took the option of the best precision.
     */
     hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
   
     /* If stepm=6 months */
     /* nhstepm age range expressed in number of stepm */
     agelim=AGESUP;
     nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
     /* if (stepm >= YEARM) hstepm=1;*/
     nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
     
     p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
     trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
     gp=matrix(0,nhstepm,1,nlstate*nlstate);
     gm=matrix(0,nhstepm,1,nlstate*nlstate);
   
     for (age=bage; age<=fage; age ++){ 
       nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
       /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
       /* if (stepm >= YEARM) hstepm=1;*/
       nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
   
       /* If stepm=6 months */
       /* Computed by stepm unit matrices, product of hstepma matrices, stored
          in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
       
       hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
   
       /* Computing  Variances of health expectancies */
       /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
          decrease memory allocation */
       for(theta=1; theta <=npar; theta++){
         for(i=1; i<=npar; i++){ 
           xp[i] = x[i] + (i==theta ?delti[theta]:0);
           xm[i] = x[i] - (i==theta ?delti[theta]:0);
         }
         hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij);  
         hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij);  
     
         for(j=1; j<= nlstate; j++){
           for(i=1; i<=nlstate; i++){
             for(h=0; h<=nhstepm-1; h++){
               gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
               gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
             }
           }
         }
        
         for(ij=1; ij<= nlstate*nlstate; ij++)
           for(h=0; h<=nhstepm-1; h++){
             gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
           }
       }/* End theta */
       
       
       for(h=0; h<=nhstepm-1; h++)
         for(j=1; j<=nlstate*nlstate;j++)
           for(theta=1; theta <=npar; theta++)
             trgradg[h][j][theta]=gradg[h][theta][j];
       
   
        for(ij=1;ij<=nlstate*nlstate;ij++)
         for(ji=1;ji<=nlstate*nlstate;ji++)
           varhe[ij][ji][(int)age] =0.;
   
        printf("%d|",(int)age);fflush(stdout);
        fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
        for(h=0;h<=nhstepm-1;h++){
         for(k=0;k<=nhstepm-1;k++){
           matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
           matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
           for(ij=1;ij<=nlstate*nlstate;ij++)
             for(ji=1;ji<=nlstate*nlstate;ji++)
               varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
         }
       }
   
       /* Computing expectancies */
       hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij);  
       for(i=1; i<=nlstate;i++)
         for(j=1; j<=nlstate;j++)
           for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
             eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
             
             /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
   
           }
   
       fprintf(ficresstdeij,"%3.0f",age );
       for(i=1; i<=nlstate;i++){
         eip=0.;
         vip=0.;
         for(j=1; j<=nlstate;j++){
           eip += eij[i][j][(int)age];
           for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
             vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
           fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
         }
         fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
       }
       fprintf(ficresstdeij,"\n");
   
       fprintf(ficrescveij,"%3.0f",age );
       for(i=1; i<=nlstate;i++)
         for(j=1; j<=nlstate;j++){
           cptj= (j-1)*nlstate+i;
           for(i2=1; i2<=nlstate;i2++)
             for(j2=1; j2<=nlstate;j2++){
               cptj2= (j2-1)*nlstate+i2;
               if(cptj2 <= cptj)
                 fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
             }
         }
       fprintf(ficrescveij,"\n");
      
     }
     free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
     free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
     free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
     free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
     free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     printf("\n");
     fprintf(ficlog,"\n");
   
     free_vector(xm,1,npar);
     free_vector(xp,1,npar);
     free_matrix(dnewm,1,nlstate*nlstate,1,npar);
     free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
     free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
   }
   
   /************ Variance ******************/
   void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[])
   {
     /* Variance of health expectancies */
     /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
     /* double **newm;*/
     double **dnewm,**doldm;
     double **dnewmp,**doldmp;
     int i, j, nhstepm, hstepm, h, nstepm ;
     int k, cptcode;
     double *xp;
     double **gp, **gm;  /* for var eij */
     double ***gradg, ***trgradg; /*for var eij */
     double **gradgp, **trgradgp; /* for var p point j */
     double *gpp, *gmp; /* for var p point j */
     double **varppt; /* for var p point j nlstate to nlstate+ndeath */
     double ***p3mat;
     double age,agelim, hf;
     double ***mobaverage;
     int theta;
     char digit[4];
     char digitp[25];
   
     char fileresprobmorprev[FILENAMELENGTH];
   
     if(popbased==1){
       if(mobilav!=0)
         strcpy(digitp,"-populbased-mobilav-");
       else strcpy(digitp,"-populbased-nomobil-");
     }
     else 
       strcpy(digitp,"-stablbased-");
   
     if (mobilav!=0) {
       mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){
         fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
         printf(" Error in movingaverage mobilav=%d\n",mobilav);
       }
     }
   
     strcpy(fileresprobmorprev,"prmorprev"); 
     sprintf(digit,"%-d",ij);
     /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
     strcat(fileresprobmorprev,digit); /* Tvar to be done */
     strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
     strcat(fileresprobmorprev,fileres);
     if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
       printf("Problem with resultfile: %s\n", fileresprobmorprev);
       fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
     }
     printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
    
     fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
     pstamp(ficresprobmorprev);
     fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
     fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
     for(j=nlstate+1; j<=(nlstate+ndeath);j++){
       fprintf(ficresprobmorprev," p.%-d SE",j);
       for(i=1; i<=nlstate;i++)
         fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
     }  
     fprintf(ficresprobmorprev,"\n");
     fprintf(ficgp,"\n# Routine varevsij");
     /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
     fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
     fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
   /*   } */
     varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
     pstamp(ficresvij);
     fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
     if(popbased==1)
       fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
     else
       fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
     fprintf(ficresvij,"# Age");
     for(i=1; i<=nlstate;i++)
       for(j=1; j<=nlstate;j++)
         fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
     fprintf(ficresvij,"\n");
   
     xp=vector(1,npar);
     dnewm=matrix(1,nlstate,1,npar);
     doldm=matrix(1,nlstate,1,nlstate);
     dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
     doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
   
     gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
     gpp=vector(nlstate+1,nlstate+ndeath);
     gmp=vector(nlstate+1,nlstate+ndeath);
     trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
     
     if(estepm < stepm){
       printf ("Problem %d lower than %d\n",estepm, stepm);
     }
     else  hstepm=estepm;   
     /* For example we decided to compute the life expectancy with the smallest unit */
     /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
        nhstepm is the number of hstepm from age to agelim 
        nstepm is the number of stepm from age to agelin. 
        Look at function hpijx to understand why (it is linked to memory size questions) */
     /* We decided (b) to get a life expectancy respecting the most precise curvature of the
        survival function given by stepm (the optimization length). Unfortunately it
        means that if the survival funtion is printed every two years of age and if
        you sum them up and add 1 year (area under the trapezoids) you won't get the same 
        results. So we changed our mind and took the option of the best precision.
     */
     hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
     agelim = AGESUP;
     for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
       nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
       nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
       gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
       gp=matrix(0,nhstepm,1,nlstate);
       gm=matrix(0,nhstepm,1,nlstate);
   
   
       for(theta=1; theta <=npar; theta++){
         for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
           xp[i] = x[i] + (i==theta ?delti[theta]:0);
         }
         hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);  
         prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);
   
         if (popbased==1) {
           if(mobilav ==0){
             for(i=1; i<=nlstate;i++)
               prlim[i][i]=probs[(int)age][i][ij];
           }else{ /* mobilav */ 
             for(i=1; i<=nlstate;i++)
               prlim[i][i]=mobaverage[(int)age][i][ij];
           }
         }
     
         for(j=1; j<= nlstate; j++){
           for(h=0; h<=nhstepm; h++){
             for(i=1, gp[h][j]=0.;i<=nlstate;i++)
               gp[h][j] += prlim[i][i]*p3mat[i][j][h];
           }
         }
         /* This for computing probability of death (h=1 means
            computed over hstepm matrices product = hstepm*stepm months) 
            as a weighted average of prlim.
         */
         for(j=nlstate+1;j<=nlstate+ndeath;j++){
           for(i=1,gpp[j]=0.; i<= nlstate; i++)
             gpp[j] += prlim[i][i]*p3mat[i][j][1];
         }    
         /* end probability of death */
   
         for(i=1; i<=npar; i++) /* Computes gradient x - delta */
           xp[i] = x[i] - (i==theta ?delti[theta]:0);
         hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);  
         prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);
    
         if (popbased==1) {
           if(mobilav ==0){
             for(i=1; i<=nlstate;i++)
               prlim[i][i]=probs[(int)age][i][ij];
           }else{ /* mobilav */ 
             for(i=1; i<=nlstate;i++)
               prlim[i][i]=mobaverage[(int)age][i][ij];
           }
         }
   
         for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
           for(h=0; h<=nhstepm; h++){
             for(i=1, gm[h][j]=0.;i<=nlstate;i++)
               gm[h][j] += prlim[i][i]*p3mat[i][j][h];
           }
         }
         /* This for computing probability of death (h=1 means
            computed over hstepm matrices product = hstepm*stepm months) 
            as a weighted average of prlim.
         */
         for(j=nlstate+1;j<=nlstate+ndeath;j++){
           for(i=1,gmp[j]=0.; i<= nlstate; i++)
            gmp[j] += prlim[i][i]*p3mat[i][j][1];
         }    
         /* end probability of death */
   
         for(j=1; j<= nlstate; j++) /* vareij */
           for(h=0; h<=nhstepm; h++){
             gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
           }
   
         for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
           gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
         }
   
       } /* End theta */
   
       trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
   
       for(h=0; h<=nhstepm; h++) /* veij */
         for(j=1; j<=nlstate;j++)
           for(theta=1; theta <=npar; theta++)
             trgradg[h][j][theta]=gradg[h][theta][j];
   
       for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
         for(theta=1; theta <=npar; theta++)
           trgradgp[j][theta]=gradgp[theta][j];
     
   
       hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
       for(i=1;i<=nlstate;i++)
         for(j=1;j<=nlstate;j++)
           vareij[i][j][(int)age] =0.;
   
       for(h=0;h<=nhstepm;h++){
         for(k=0;k<=nhstepm;k++){
           matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
           matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
           for(i=1;i<=nlstate;i++)
             for(j=1;j<=nlstate;j++)
               vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
         }
       }
     
       /* pptj */
       matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
       matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
       for(j=nlstate+1;j<=nlstate+ndeath;j++)
         for(i=nlstate+1;i<=nlstate+ndeath;i++)
           varppt[j][i]=doldmp[j][i];
       /* end ppptj */
       /*  x centered again */
       hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij);  
       prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ij);
    
       if (popbased==1) {
         if(mobilav ==0){
           for(i=1; i<=nlstate;i++)
             prlim[i][i]=probs[(int)age][i][ij];
         }else{ /* mobilav */ 
           for(i=1; i<=nlstate;i++)
             prlim[i][i]=mobaverage[(int)age][i][ij];
         }
       }
                
       /* This for computing probability of death (h=1 means
          computed over hstepm (estepm) matrices product = hstepm*stepm months) 
          as a weighted average of prlim.
       */
       for(j=nlstate+1;j<=nlstate+ndeath;j++){
         for(i=1,gmp[j]=0.;i<= nlstate; i++) 
           gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
       }    
       /* end probability of death */
   
       fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
       for(j=nlstate+1; j<=(nlstate+ndeath);j++){
         fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
         for(i=1; i<=nlstate;i++){
           fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
         }
       } 
       fprintf(ficresprobmorprev,"\n");
   
       fprintf(ficresvij,"%.0f ",age );
       for(i=1; i<=nlstate;i++)
         for(j=1; j<=nlstate;j++){
           fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
         }
       fprintf(ficresvij,"\n");
       free_matrix(gp,0,nhstepm,1,nlstate);
       free_matrix(gm,0,nhstepm,1,nlstate);
       free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
       free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     } /* End age */
     free_vector(gpp,nlstate+1,nlstate+ndeath);
     free_vector(gmp,nlstate+1,nlstate+ndeath);
     free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
     free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
     fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240");
     /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
     fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
   /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
   /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
   /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
     fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
     fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95\%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
     fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
     fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
     fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.png\"> <br>\n", estepm,subdirf3(optionfilefiname,"varmuptjgr",digitp),digit);
     /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.png\"> <br>\n", stepm,YEARM,digitp,digit);
   */
   /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.png\";replot;",digitp,optionfilefiname,digit); */
     fprintf(ficgp,"\nset out \"%s%s.png\";replot;\n",subdirf3(optionfilefiname,"varmuptjgr",digitp),digit);
   
     free_vector(xp,1,npar);
     free_matrix(doldm,1,nlstate,1,nlstate);
     free_matrix(dnewm,1,nlstate,1,npar);
     free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
     free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
     free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
     if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     fclose(ficresprobmorprev);
     fflush(ficgp);
     fflush(fichtm); 
   }  /* end varevsij */
   
   /************ Variance of prevlim ******************/
   void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij, char strstart[])
   {
     /* Variance of prevalence limit */
     /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
     double **newm;
     double **dnewm,**doldm;
     int i, j, nhstepm, hstepm;
     int k, cptcode;
     double *xp;
     double *gp, *gm;
     double **gradg, **trgradg;
     double age,agelim;
     int theta;
     
     pstamp(ficresvpl);
     fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
     fprintf(ficresvpl,"# Age");
     for(i=1; i<=nlstate;i++)
         fprintf(ficresvpl," %1d-%1d",i,i);
     fprintf(ficresvpl,"\n");
   
     xp=vector(1,npar);
     dnewm=matrix(1,nlstate,1,npar);
     doldm=matrix(1,nlstate,1,nlstate);
     
     hstepm=1*YEARM; /* Every year of age */
     hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
     agelim = AGESUP;
     for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
       nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
       if (stepm >= YEARM) hstepm=1;
       nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
       gradg=matrix(1,npar,1,nlstate);
       gp=vector(1,nlstate);
       gm=vector(1,nlstate);
   
       for(theta=1; theta <=npar; theta++){
         for(i=1; i<=npar; i++){ /* Computes gradient */
           xp[i] = x[i] + (i==theta ?delti[theta]:0);
         }
         prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);
         for(i=1;i<=nlstate;i++)
           gp[i] = prlim[i][i];
       
         for(i=1; i<=npar; i++) /* Computes gradient */
           xp[i] = x[i] - (i==theta ?delti[theta]:0);
         prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);
         for(i=1;i<=nlstate;i++)
           gm[i] = prlim[i][i];
   
         for(i=1;i<=nlstate;i++)
           gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
       } /* End theta */
   
       trgradg =matrix(1,nlstate,1,npar);
   
       for(j=1; j<=nlstate;j++)
         for(theta=1; theta <=npar; theta++)
           trgradg[j][theta]=gradg[theta][j];
   
       for(i=1;i<=nlstate;i++)
         varpl[i][(int)age] =0.;
       matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
       matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
       for(i=1;i<=nlstate;i++)
         varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
   
       fprintf(ficresvpl,"%.0f ",age );
       for(i=1; i<=nlstate;i++)
         fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
       fprintf(ficresvpl,"\n");
       free_vector(gp,1,nlstate);
       free_vector(gm,1,nlstate);
       free_matrix(gradg,1,npar,1,nlstate);
       free_matrix(trgradg,1,nlstate,1,npar);
     } /* End age */
   
     free_vector(xp,1,npar);
     free_matrix(doldm,1,nlstate,1,npar);
     free_matrix(dnewm,1,nlstate,1,nlstate);
   
   }
   
   /************ Variance of one-step probabilities  ******************/
   void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
   {
     int i, j=0,  i1, k1, l1, t, tj;
     int k2, l2, j1,  z1;
     int k=0,l, cptcode;
     int first=1, first1, first2;
     double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
     double **dnewm,**doldm;
     double *xp;
     double *gp, *gm;
     double **gradg, **trgradg;
     double **mu;
     double age,agelim, cov[NCOVMAX+1];
     double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
     int theta;
     char fileresprob[FILENAMELENGTH];
     char fileresprobcov[FILENAMELENGTH];
     char fileresprobcor[FILENAMELENGTH];
     double ***varpij;
   
     strcpy(fileresprob,"prob"); 
     strcat(fileresprob,fileres);
     if((ficresprob=fopen(fileresprob,"w"))==NULL) {
       printf("Problem with resultfile: %s\n", fileresprob);
       fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
     }
     strcpy(fileresprobcov,"probcov"); 
     strcat(fileresprobcov,fileres);
     if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
       printf("Problem with resultfile: %s\n", fileresprobcov);
       fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
     }
     strcpy(fileresprobcor,"probcor"); 
     strcat(fileresprobcor,fileres);
     if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
       printf("Problem with resultfile: %s\n", fileresprobcor);
       fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
     }
     printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
     fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
     printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
     fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
     printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
     fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
     pstamp(ficresprob);
     fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
     fprintf(ficresprob,"# Age");
     pstamp(ficresprobcov);
     fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
     fprintf(ficresprobcov,"# Age");
     pstamp(ficresprobcor);
     fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
     fprintf(ficresprobcor,"# Age");
   
   
     for(i=1; i<=nlstate;i++)
       for(j=1; j<=(nlstate+ndeath);j++){
         fprintf(ficresprob," p%1d-%1d (SE)",i,j);
         fprintf(ficresprobcov," p%1d-%1d ",i,j);
         fprintf(ficresprobcor," p%1d-%1d ",i,j);
       }  
    /* fprintf(ficresprob,"\n");
     fprintf(ficresprobcov,"\n");
     fprintf(ficresprobcor,"\n");
    */
     xp=vector(1,npar);
     dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
     doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
     mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
     varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
     first=1;
     fprintf(ficgp,"\n# Routine varprob");
     fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
     fprintf(fichtm,"\n");
   
     fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of pairs of step probabilities (drawings)</a></h4></li>\n",optionfilehtmcov);
     fprintf(fichtmcov,"\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n\
     file %s<br>\n",optionfilehtmcov);
     fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated\
   and drawn. It helps understanding how is the covariance between two incidences.\
    They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
     fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
   It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
   would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
   standard deviations wide on each axis. <br>\
    Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
    and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
   To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
   
     cov[1]=1;
     /* tj=cptcoveff; */
     tj = (int) pow(2,cptcoveff);
     if (cptcovn<1) {tj=1;ncodemax[1]=1;}
     j1=0;
     for(j1=1; j1<=tj;j1++){
       /*for(i1=1; i1<=ncodemax[t];i1++){ */
       /*j1++;*/
         if  (cptcovn>0) {
           fprintf(ficresprob, "\n#********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
           fprintf(ficresprob, "**********\n#\n");
           fprintf(ficresprobcov, "\n#********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
           fprintf(ficresprobcov, "**********\n#\n");
           
           fprintf(ficgp, "\n#********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
           fprintf(ficgp, "**********\n#\n");
           
           
           fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
           fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
           
           fprintf(ficresprobcor, "\n#********** Variable ");    
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
           fprintf(ficresprobcor, "**********\n#");    
         }
         
         gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
         trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
         gp=vector(1,(nlstate)*(nlstate+ndeath));
         gm=vector(1,(nlstate)*(nlstate+ndeath));
         for (age=bage; age<=fage; age ++){ 
           cov[2]=age;
           for (k=1; k<=cptcovn;k++) {
             cov[2+k]=nbcode[Tvar[k]][codtab[j1][Tvar[k]]];/* j1 1 2 3 4
                                                            * 1  1 1 1 1
                                                            * 2  2 1 1 1
                                                            * 3  1 2 1 1
                                                            */
             /* nbcode[1][1]=0 nbcode[1][2]=1;*/
           }
           for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];
           for (k=1; k<=cptcovprod;k++)
             cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];
           
       
           for(theta=1; theta <=npar; theta++){
             for(i=1; i<=npar; i++)
               xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
             
             pmij(pmmij,cov,ncovmodel,xp,nlstate);
             
             k=0;
             for(i=1; i<= (nlstate); i++){
               for(j=1; j<=(nlstate+ndeath);j++){
                 k=k+1;
                 gp[k]=pmmij[i][j];
               }
             }
             
             for(i=1; i<=npar; i++)
               xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
       
             pmij(pmmij,cov,ncovmodel,xp,nlstate);
             k=0;
             for(i=1; i<=(nlstate); i++){
               for(j=1; j<=(nlstate+ndeath);j++){
                 k=k+1;
                 gm[k]=pmmij[i][j];
               }
             }
        
             for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
               gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
           }
   
           for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
             for(theta=1; theta <=npar; theta++)
               trgradg[j][theta]=gradg[theta][j];
           
           matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
           matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
   
           pmij(pmmij,cov,ncovmodel,x,nlstate);
           
           k=0;
           for(i=1; i<=(nlstate); i++){
             for(j=1; j<=(nlstate+ndeath);j++){
               k=k+1;
               mu[k][(int) age]=pmmij[i][j];
             }
           }
           for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
             for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
               varpij[i][j][(int)age] = doldm[i][j];
   
           /*printf("\n%d ",(int)age);
             for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
             printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
             fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
             }*/
   
           fprintf(ficresprob,"\n%d ",(int)age);
           fprintf(ficresprobcov,"\n%d ",(int)age);
           fprintf(ficresprobcor,"\n%d ",(int)age);
   
           for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
             fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
           for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
             fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
             fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
           }
           i=0;
           for (k=1; k<=(nlstate);k++){
             for (l=1; l<=(nlstate+ndeath);l++){ 
               i++;
               fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
               fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
               for (j=1; j<=i;j++){
                 /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                 fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                 fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
               }
             }
           }/* end of loop for state */
         } /* end of loop for age */
         free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
         free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
         free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
         free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
         
         /* Confidence intervalle of pij  */
         /*
           fprintf(ficgp,"\nunset parametric;unset label");
           fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
           fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
           fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
           fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
           fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
           fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
         */
   
         /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
         first1=1;first2=2;
         for (k2=1; k2<=(nlstate);k2++){
           for (l2=1; l2<=(nlstate+ndeath);l2++){ 
             if(l2==k2) continue;
             j=(k2-1)*(nlstate+ndeath)+l2;
             for (k1=1; k1<=(nlstate);k1++){
               for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                 if(l1==k1) continue;
                 i=(k1-1)*(nlstate+ndeath)+l1;
                 if(i<=j) continue;
                 for (age=bage; age<=fage; age ++){ 
                   if ((int)age %5==0){
                     v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                     v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                     cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                     mu1=mu[i][(int) age]/stepm*YEARM ;
                     mu2=mu[j][(int) age]/stepm*YEARM;
                     c12=cv12/sqrt(v1*v2);
                     /* Computing eigen value of matrix of covariance */
                     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                     if ((lc2 <0) || (lc1 <0) ){
                       if(first2==1){
                         first1=0;
                       printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                       }
                       fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                       /* lc1=fabs(lc1); */ /* If we want to have them positive */
                       /* lc2=fabs(lc2); */
                     }
   
                     /* Eigen vectors */
                     v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                     /*v21=sqrt(1.-v11*v11); *//* error */
                     v21=(lc1-v1)/cv12*v11;
                     v12=-v21;
                     v22=v11;
                     tnalp=v21/v11;
                     if(first1==1){
                       first1=0;
                       printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                     }
                     fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                     /*printf(fignu*/
                     /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                     /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                     if(first==1){
                       first=0;
                       fprintf(ficgp,"\nset parametric;unset label");
                       fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                       fprintf(ficgp,"\nset ter png small size 320, 240");
                       fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
    :<a href=\"%s%d%1d%1d-%1d%1d.png\">\
   %s%d%1d%1d-%1d%1d.png</A>, ",k1,l1,k2,l2,\
                               subdirf2(optionfilefiname,"varpijgr"), j1,k1,l1,k2,l2,\
                               subdirf2(optionfilefiname,"varpijgr"), j1,k1,l1,k2,l2);
                       fprintf(fichtmcov,"\n<br><img src=\"%s%d%1d%1d-%1d%1d.png\"> ",subdirf2(optionfilefiname,"varpijgr"), j1,k1,l1,k2,l2);
                       fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                       fprintf(ficgp,"\nset out \"%s%d%1d%1d-%1d%1d.png\"",subdirf2(optionfilefiname,"varpijgr"), j1,k1,l1,k2,l2);
                       fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                       fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                       fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",\
                               mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),\
                               mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                     }else{
                       first=0;
                       fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                       fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                       fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                       fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",\
                               mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),\
                               mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                     }/* if first */
                   } /* age mod 5 */
                 } /* end loop age */
                 fprintf(ficgp,"\nset out \"%s%d%1d%1d-%1d%1d.png\";replot;",subdirf2(optionfilefiname,"varpijgr"), j1,k1,l1,k2,l2);
                 first=1;
               } /*l12 */
             } /* k12 */
           } /*l1 */
         }/* k1 */
         /* } /* loop covariates */
     }
     free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
     free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
     free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
     free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
     free_vector(xp,1,npar);
     fclose(ficresprob);
     fclose(ficresprobcov);
     fclose(ficresprobcor);
     fflush(ficgp);
     fflush(fichtmcov);
   }
   
   
   /******************* Printing html file ***********/
   void printinghtml(char fileres[], char title[], char datafile[], int firstpass, \
                     int lastpass, int stepm, int weightopt, char model[],\
                     int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
                     int popforecast, int estepm ,\
                     double jprev1, double mprev1,double anprev1, \
                     double jprev2, double mprev2,double anprev2){
     int jj1, k1, i1, cpt;
   
      fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
      <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
   </ul>");
      fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n \
    - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> <br>\n ",
              jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirf2(fileres,"p"),subdirf2(fileres,"p"));
      fprintf(fichtm,"\
    - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
              stepm,subdirf2(fileres,"pij"),subdirf2(fileres,"pij"));
      fprintf(fichtm,"\
    - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
              subdirf2(fileres,"pl"),subdirf2(fileres,"pl"));
      fprintf(fichtm,"\
    - (a) Life expectancies by health status at initial age, ei. (b) health expectancies by health status at initial age, eij . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
      <a href=\"%s\">%s</a> <br>\n",
              estepm,subdirf2(fileres,"e"),subdirf2(fileres,"e"));
      fprintf(fichtm,"\
    - Population projections by age and states: \
      <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileres,"f"),subdirf2(fileres,"f"));
   
   fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
   
    m=pow(2,cptcoveff);
    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
   
    jj1=0;
    for(k1=1; k1<=m;k1++){
      for(i1=1; i1<=ncodemax[k1];i1++){
        jj1++;
        if (cptcovn > 0) {
          fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
          for (cpt=1; cpt<=cptcoveff;cpt++) 
            fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtab[jj1][cpt]]);
          fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
        }
        /* Pij */
        fprintf(fichtm,"<br>- Pij or Conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s%d_1.png\">%s%d_1.png</a><br> \
   <img src=\"%s%d_1.png\">",stepm,subdirf2(optionfilefiname,"pe"),jj1,subdirf2(optionfilefiname,"pe"),jj1,subdirf2(optionfilefiname,"pe"),jj1);     
        /* Quasi-incidences */
        fprintf(fichtm,"<br>- Pij or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
    before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too: <a href=\"%s%d_2.png\">%s%d_2.png</a><br> \
   <img src=\"%s%d_2.png\">",stepm,subdirf2(optionfilefiname,"pe"),jj1,subdirf2(optionfilefiname,"pe"),jj1,subdirf2(optionfilefiname,"pe"),jj1); 
          /* Period (stable) prevalence in each health state */
          for(cpt=1; cpt<=nlstate;cpt++){
            fprintf(fichtm,"<br>- Convergence from each state (1 to %d) to period (stable) prevalence in state %d <a href=\"%s%d_%d.png\">%s%d_%d.png</a><br> \
   <img src=\"%s%d_%d.png\">",nlstate, cpt, subdirf2(optionfilefiname,"p"),cpt,jj1,subdirf2(optionfilefiname,"p"),cpt,jj1,subdirf2(optionfilefiname,"p"),cpt,jj1);
          }
        for(cpt=1; cpt<=nlstate;cpt++) {
           fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) : <a href=\"%s%d%d.png\">%s%d%d.png</a> <br> \
   <img src=\"%s%d%d.png\">",cpt,nlstate,subdirf2(optionfilefiname,"exp"),cpt,jj1,subdirf2(optionfilefiname,"exp"),cpt,jj1,subdirf2(optionfilefiname,"exp"),cpt,jj1);
        }
      } /* end i1 */
    }/* End k1 */
    fprintf(fichtm,"</ul>");
   
   
    fprintf(fichtm,"\
   \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
    - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br>\n", rfileres,rfileres);
   
    fprintf(fichtm," - Variance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
            subdirf2(fileres,"prob"),subdirf2(fileres,"prob"));
    fprintf(fichtm,"\
    - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
            subdirf2(fileres,"probcov"),subdirf2(fileres,"probcov"));
   
    fprintf(fichtm,"\
    - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
            subdirf2(fileres,"probcor"),subdirf2(fileres,"probcor"));
    fprintf(fichtm,"\
    - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
      <a href=\"%s\">%s</a> <br>\n</li>",
              estepm,subdirf2(fileres,"cve"),subdirf2(fileres,"cve"));
    fprintf(fichtm,"\
    - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
      <a href=\"%s\">%s</a> <br>\n</li>",
              estepm,subdirf2(fileres,"stde"),subdirf2(fileres,"stde"));
    fprintf(fichtm,"\
    - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
            estepm, subdirf2(fileres,"v"),subdirf2(fileres,"v"));
    fprintf(fichtm,"\
    - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
            estepm, subdirf2(fileres,"t"),subdirf2(fileres,"t"));
    fprintf(fichtm,"\
    - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
            subdirf2(fileres,"vpl"),subdirf2(fileres,"vpl"));
   
   /*  if(popforecast==1) fprintf(fichtm,"\n */
   /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
   /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
   /*      <br>",fileres,fileres,fileres,fileres); */
   /*  else  */
   /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
    fflush(fichtm);
    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
   
    m=pow(2,cptcoveff);
    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
   
    jj1=0;
    for(k1=1; k1<=m;k1++){
      for(i1=1; i1<=ncodemax[k1];i1++){
        jj1++;
        if (cptcovn > 0) {
          fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
          for (cpt=1; cpt<=cptcoveff;cpt++) 
            fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtab[jj1][cpt]]);
          fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
        }
        for(cpt=1; cpt<=nlstate;cpt++) {
          fprintf(fichtm,"<br>- Observed (cross-sectional) and period (incidence based) \
   prevalence (with 95%% confidence interval) in state (%d): %s%d_%d.png <br>\
   <img src=\"%s%d_%d.png\">",cpt,subdirf2(optionfilefiname,"v"),cpt,jj1,subdirf2(optionfilefiname,"v"),cpt,jj1);  
        }
        fprintf(fichtm,"\n<br>- Total life expectancy by age and \
   health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
   true period expectancies (those weighted with period prevalences are also\
    drawn in addition to the population based expectancies computed using\
    observed and cahotic prevalences: %s%d.png<br>\
   <img src=\"%s%d.png\">",subdirf2(optionfilefiname,"e"),jj1,subdirf2(optionfilefiname,"e"),jj1);
      } /* end i1 */
    }/* End k1 */
    fprintf(fichtm,"</ul>");
    fflush(fichtm);
   }
   
   /******************* Gnuplot file **************/
   void printinggnuplot(char fileres[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
   
     char dirfileres[132],optfileres[132];
     int m0,cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,ij=0,l=0;
     int ng=0;
   /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
   /*     printf("Problem with file %s",optionfilegnuplot); */
   /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
   /*   } */
   
     /*#ifdef windows */
     fprintf(ficgp,"cd \"%s\" \n",pathc);
       /*#endif */
     m=pow(2,cptcoveff);
   
     strcpy(dirfileres,optionfilefiname);
     strcpy(optfileres,"vpl");
    /* 1eme*/
     fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'vpl' files\n");
     for (cpt=1; cpt<= nlstate ; cpt ++) {
       for (k1=1; k1<= m ; k1 ++) { /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
        fprintf(ficgp,"\nset out \"%s%d_%d.png\" \n",subdirf2(optionfilefiname,"v"),cpt,k1);
        fprintf(ficgp,"\n#set out \"v%s%d_%d.png\" \n",optionfilefiname,cpt,k1);
        fprintf(ficgp,"set xlabel \"Age\" \n\
   set ylabel \"Probability\" \n\
   set ter png small size 320, 240\n\
   plot [%.f:%.f] \"%s\" every :::%d::%d u 1:2 \"\%%lf",ageminpar,fage,subdirf2(fileres,"vpl"),k1-1,k1-1);
   
        for (i=1; i<= nlstate ; i ++) {
          if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");
          else        fprintf(ficgp," \%%*lf (\%%*lf)");
        }
        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2+1.96*$3) \"\%%lf",subdirf2(fileres,"vpl"),k1-1,k1-1);
        for (i=1; i<= nlstate ; i ++) {
          if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");
          else fprintf(ficgp," \%%*lf (\%%*lf)");
        } 
        fprintf(ficgp,"\" t\"95\%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2-1.96*$3) \"\%%lf",subdirf2(fileres,"vpl"),k1-1,k1-1); 
        for (i=1; i<= nlstate ; i ++) {
          if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");
          else fprintf(ficgp," \%%*lf (\%%*lf)");
        }  
        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence \" w l lt 2",subdirf2(fileres,"p"),k1-1,k1-1,2+4*(cpt-1));
      }
     }
     /*2 eme*/
     fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files\n");
     for (k1=1; k1<= m ; k1 ++) { 
       fprintf(ficgp,"\nset out \"%s%d.png\" \n",subdirf2(optionfilefiname,"e"),k1);
       fprintf(ficgp,"set ylabel \"Years\" \nset ter png small size 320, 240\nplot [%.f:%.f] ",ageminpar,fage);
       
       for (i=1; i<= nlstate+1 ; i ++) {
         k=2*i;
         fprintf(ficgp,"\"%s\" every :::%d::%d u 1:2 \"\%%lf",subdirf2(fileres,"t"),k1-1,k1-1);
         for (j=1; j<= nlstate+1 ; j ++) {
           if (j==i) fprintf(ficgp," \%%lf (\%%lf)");
           else fprintf(ficgp," \%%*lf (\%%*lf)");
         }   
         if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l ,");
         else fprintf(ficgp,"\" t\"LE in state (%d)\" w l ,",i-1);
         fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2-$3*2) \"\%%lf",subdirf2(fileres,"t"),k1-1,k1-1);
         for (j=1; j<= nlstate+1 ; j ++) {
           if (j==i) fprintf(ficgp," \%%lf (\%%lf)");
           else fprintf(ficgp," \%%*lf (\%%*lf)");
         }   
         fprintf(ficgp,"\" t\"\" w l lt 0,");
         fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2+$3*2) \"\%%lf",subdirf2(fileres,"t"),k1-1,k1-1);
         for (j=1; j<= nlstate+1 ; j ++) {
           if (j==i) fprintf(ficgp," \%%lf (\%%lf)");
           else fprintf(ficgp," \%%*lf (\%%*lf)");
         }   
         if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
         else fprintf(ficgp,"\" t\"\" w l lt 0,");
       }
     }
     
     /*3eme*/
     
     for (k1=1; k1<= m ; k1 ++) { 
       for (cpt=1; cpt<= nlstate ; cpt ++) {
         /*       k=2+nlstate*(2*cpt-2); */
         k=2+(nlstate+1)*(cpt-1);
         fprintf(ficgp,"\nset out \"%s%d%d.png\" \n",subdirf2(optionfilefiname,"exp"),cpt,k1);
         fprintf(ficgp,"set ter png small size 320, 240\n\
   plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileres,"e"),k1-1,k1-1,k,cpt);
         /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
           for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
           fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
           fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
           for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
           fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
           
         */
         for (i=1; i< nlstate ; i ++) {
           fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+i,cpt,i+1);
           /*      fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
           
         } 
         fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+nlstate,cpt);
       }
     }
     
     /* CV preval stable (period) */
     for (k1=1; k1<= m ; k1 ++) { /* For each multivariate if any */
       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
         k=3;
         fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, cov=%d state=%d",k1, cpt);
         fprintf(ficgp,"\nset out \"%s%d_%d.png\" \n",subdirf2(optionfilefiname,"p"),cpt,k1);
         fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
   set ter png small size 320, 240\n\
   unset log y\n\
   plot [%.f:%.f]  ", ageminpar, agemaxpar);
         for (i=1; i<= nlstate ; i ++){
           if(i==1)
             fprintf(ficgp,"\"%s\"",subdirf2(fileres,"pij"));
           else
             fprintf(ficgp,", '' ");
           l=(nlstate+ndeath)*(i-1)+1;
           fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
           for (j=1; j<= (nlstate-1) ; j ++)
             fprintf(ficgp,"+$%d",k+l+j);
           fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
         } /* nlstate */
         fprintf(ficgp,"\n");
       } /* end cpt state*/ 
     } /* end covariate */  
     
     /* proba elementaires */
     for(i=1,jk=1; i <=nlstate; i++){
       for(k=1; k <=(nlstate+ndeath); k++){
         if (k != i) {
           for(j=1; j <=ncovmodel; j++){
             fprintf(ficgp,"p%d=%f ",jk,p[jk]);
             jk++; 
             fprintf(ficgp,"\n");
           }
         }
       }
      }
     /*goto avoid;*/
      for(ng=1; ng<=2;ng++){ /* Number of graphics: first is probabilities second is incidence per year*/
        for(jk=1; jk <=m; jk++) {
          fprintf(ficgp,"\nset out \"%s%d_%d.png\" \n",subdirf2(optionfilefiname,"pe"),jk,ng); 
          if (ng==2)
            fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
          else
            fprintf(ficgp,"\nset title \"Probability\"\n");
          fprintf(ficgp,"\nset ter png small size 320, 240\nset log y\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
          i=1;
          for(k2=1; k2<=nlstate; k2++) {
            k3=i;
            for(k=1; k<=(nlstate+ndeath); k++) {
              if (k != k2){
                if(ng==2)
                  fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                else
                  fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                ij=1;/* To be checked else nbcode[0][0] wrong */
                for(j=3; j <=ncovmodel; j++) {
                  /* if(((j-2)==Tage[ij]) &&(ij <=cptcovage)) { /\* Bug valgrind *\/ */
                  /*        /\*fprintf(ficgp,"+p%d*%d*x",i+j-1,nbcode[Tvar[j-2]][codtab[jk][Tvar[j-2]]]);*\/ */
                  /*        ij++; */
                  /* } */
                  /* else */
                    fprintf(ficgp,"+p%d*%d",i+j-1,nbcode[Tvar[j-2]][codtab[jk][j-2]]);
                }
                fprintf(ficgp,")/(1");
                
                for(k1=1; k1 <=nlstate; k1++){   
                  fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                  ij=1;
                  for(j=3; j <=ncovmodel; j++){
                    /* if(((j-2)==Tage[ij]) &&(ij <=cptcovage)) { */
                    /*   fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2,nbcode[Tvar[j-2]][codtab[jk][Tvar[j-2]]]); */
                    /*   ij++; */
                    /* } */
                    /* else */
                      fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2,nbcode[Tvar[j-2]][codtab[jk][j-2]]);
                  }
                  fprintf(ficgp,")");
                }
                fprintf(ficgp,") t \"p%d%d\" ", k2,k);
                if ((k+k2)!= (nlstate*2+ndeath)) fprintf(ficgp,",");
                i=i+ncovmodel;
              }
            } /* end k */
          } /* end k2 */
        } /* end jk */
      } /* end ng */
    avoid:
      fflush(ficgp); 
   }  /* end gnuplot */
   
   
   /*************** Moving average **************/
   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav){
   
     int i, cpt, cptcod;
     int modcovmax =1;
     int mobilavrange, mob;
     double age;
   
     modcovmax=2*cptcoveff;/* Max number of modalities. We suppose 
                              a covariate has 2 modalities */
     if (cptcovn<1) modcovmax=1; /* At least 1 pass */
   
     if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
       if(mobilav==1) mobilavrange=5; /* default */
       else mobilavrange=mobilav;
       for (age=bage; age<=fage; age++)
         for (i=1; i<=nlstate;i++)
           for (cptcod=1;cptcod<=modcovmax;cptcod++)
             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
       /* We keep the original values on the extreme ages bage, fage and for 
          fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
          we use a 5 terms etc. until the borders are no more concerned. 
       */ 
       for (mob=3;mob <=mobilavrange;mob=mob+2){
         for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
           for (i=1; i<=nlstate;i++){
             for (cptcod=1;cptcod<=modcovmax;cptcod++){
               mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                 for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                 }
               mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
             }
           }
         }/* end age */
       }/* end mob */
     }else return -1;
     return 0;
   }/* End movingaverage */
   
   
   /************** Forecasting ******************/
   prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
     /* proj1, year, month, day of starting projection 
        agemin, agemax range of age
        dateprev1 dateprev2 range of dates during which prevalence is computed
        anproj2 year of en of projection (same day and month as proj1).
     */
     int yearp, stepsize, hstepm, nhstepm, j, k, c, cptcod, i, h, i1;
     int *popage;
     double agec; /* generic age */
     double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
     double *popeffectif,*popcount;
     double ***p3mat;
     double ***mobaverage;
     char fileresf[FILENAMELENGTH];
   
     agelim=AGESUP;
     prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
    
     strcpy(fileresf,"f"); 
     strcat(fileresf,fileres);
     if((ficresf=fopen(fileresf,"w"))==NULL) {
       printf("Problem with forecast resultfile: %s\n", fileresf);
       fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
     }
     printf("Computing forecasting: result on file '%s' \n", fileresf);
     fprintf(ficlog,"Computing forecasting: result on file '%s' \n", fileresf);
   
     if (cptcoveff==0) ncodemax[cptcoveff]=1;
   
     if (mobilav!=0) {
       mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){
         fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
         printf(" Error in movingaverage mobilav=%d\n",mobilav);
       }
     }
   
     stepsize=(int) (stepm+YEARM-1)/YEARM;
     if (stepm<=12) stepsize=1;
     if(estepm < stepm){
       printf ("Problem %d lower than %d\n",estepm, stepm);
     }
     else  hstepm=estepm;   
   
     hstepm=hstepm/stepm; 
     yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                                  fractional in yp1 */
     anprojmean=yp;
     yp2=modf((yp1*12),&yp);
     mprojmean=yp;
     yp1=modf((yp2*30.5),&yp);
     jprojmean=yp;
     if(jprojmean==0) jprojmean=1;
     if(mprojmean==0) jprojmean=1;
   
     i1=cptcoveff;
     if (cptcovn < 1){i1=1;}
     
     fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
     
     fprintf(ficresf,"#****** Routine prevforecast **\n");
   
   /*            if (h==(int)(YEARM*yearp)){ */
     for(cptcov=1, k=0;cptcov<=i1;cptcov++){
       for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){
         k=k+1;
         fprintf(ficresf,"\n#******");
         for(j=1;j<=cptcoveff;j++) {
           fprintf(ficresf," V%d=%d, hpijx=probability over h years, hp.jx is weighted by observed prev ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
         }
         fprintf(ficresf,"******\n");
         fprintf(ficresf,"# Covariate valuofcovar yearproj age");
         for(j=1; j<=nlstate+ndeath;j++){ 
           for(i=1; i<=nlstate;i++)              
             fprintf(ficresf," p%d%d",i,j);
           fprintf(ficresf," p.%d",j);
         }
         for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) { 
           fprintf(ficresf,"\n");
           fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
   
           for (agec=fage; agec>=(ageminpar-1); agec--){ 
             nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
             nhstepm = nhstepm/hstepm; 
             p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             oldm=oldms;savm=savms;
             hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k);  
           
             for (h=0; h<=nhstepm; h++){
               if (h*hstepm/YEARM*stepm ==yearp) {
                 fprintf(ficresf,"\n");
                 for(j=1;j<=cptcoveff;j++) 
                   fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
                 fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
               } 
               for(j=1; j<=nlstate+ndeath;j++) {
                 ppij=0.;
                 for(i=1; i<=nlstate;i++) {
                   if (mobilav==1) 
                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod];
                   else {
                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod];
                   }
                   if (h*hstepm/YEARM*stepm== yearp) {
                     fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   }
                 } /* end i */
                 if (h*hstepm/YEARM*stepm==yearp) {
                   fprintf(ficresf," %.3f", ppij);
                 }
               }/* end j */
             } /* end h */
             free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           } /* end agec */
         } /* end yearp */
       } /* end cptcod */
     } /* end  cptcov */
          
     if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
   
     fclose(ficresf);
   }
   
   /************** Forecasting *****not tested NB*************/
   populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){
     
     int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h;
     int *popage;
     double calagedatem, agelim, kk1, kk2;
     double *popeffectif,*popcount;
     double ***p3mat,***tabpop,***tabpopprev;
     double ***mobaverage;
     char filerespop[FILENAMELENGTH];
   
     tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     agelim=AGESUP;
     calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM;
     
     prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
     
     
     strcpy(filerespop,"pop"); 
     strcat(filerespop,fileres);
     if((ficrespop=fopen(filerespop,"w"))==NULL) {
       printf("Problem with forecast resultfile: %s\n", filerespop);
       fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop);
     }
     printf("Computing forecasting: result on file '%s' \n", filerespop);
     fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop);
   
     if (cptcoveff==0) ncodemax[cptcoveff]=1;
   
     if (mobilav!=0) {
       mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){
         fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
         printf(" Error in movingaverage mobilav=%d\n",mobilav);
       }
     }
   
     stepsize=(int) (stepm+YEARM-1)/YEARM;
     if (stepm<=12) stepsize=1;
     
     agelim=AGESUP;
     
     hstepm=1;
     hstepm=hstepm/stepm; 
     
     if (popforecast==1) {
       if((ficpop=fopen(popfile,"r"))==NULL) {
         printf("Problem with population file : %s\n",popfile);exit(0);
         fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0);
       } 
       popage=ivector(0,AGESUP);
       popeffectif=vector(0,AGESUP);
       popcount=vector(0,AGESUP);
       
       i=1;   
       while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1;
      
       imx=i;
       for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i];
     }
   
     for(cptcov=1,k=0;cptcov<=i2;cptcov++){
      for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){
         k=k+1;
         fprintf(ficrespop,"\n#******");
         for(j=1;j<=cptcoveff;j++) {
           fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
         }
         fprintf(ficrespop,"******\n");
         fprintf(ficrespop,"# Age");
         for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j);
         if (popforecast==1)  fprintf(ficrespop," [Population]");
         
         for (cpt=0; cpt<=0;cpt++) { 
           fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);   
           
           for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){ 
             nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); 
             nhstepm = nhstepm/hstepm; 
             
             p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             oldm=oldms;savm=savms;
             hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
           
             for (h=0; h<=nhstepm; h++){
               if (h==(int) (calagedatem+YEARM*cpt)) {
                 fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm);
               } 
               for(j=1; j<=nlstate+ndeath;j++) {
                 kk1=0.;kk2=0;
                 for(i=1; i<=nlstate;i++) {              
                   if (mobilav==1) 
                     kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod];
                   else {
                     kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod];
                   }
                 }
                 if (h==(int)(calagedatem+12*cpt)){
                   tabpop[(int)(agedeb)][j][cptcod]=kk1;
                     /*fprintf(ficrespop," %.3f", kk1);
                       if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*/
                 }
               }
               for(i=1; i<=nlstate;i++){
                 kk1=0.;
                   for(j=1; j<=nlstate;j++){
                     kk1= kk1+tabpop[(int)(agedeb)][j][cptcod]; 
                   }
                     tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)];
               }
   
               if (h==(int)(calagedatem+12*cpt)) for(j=1; j<=nlstate;j++) 
                 fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]);
             }
             free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           }
         }
    
     /******/
   
         for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) { 
           fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);   
           for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){ 
             nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); 
             nhstepm = nhstepm/hstepm; 
             
             p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             oldm=oldms;savm=savms;
             hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
             for (h=0; h<=nhstepm; h++){
               if (h==(int) (calagedatem+YEARM*cpt)) {
                 fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm);
               } 
               for(j=1; j<=nlstate+ndeath;j++) {
                 kk1=0.;kk2=0;
                 for(i=1; i<=nlstate;i++) {              
                   kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];    
                 }
                 if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);        
               }
             }
             free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           }
         }
      } 
     }
    
     if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
   
     if (popforecast==1) {
       free_ivector(popage,0,AGESUP);
       free_vector(popeffectif,0,AGESUP);
       free_vector(popcount,0,AGESUP);
     }
     free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     fclose(ficrespop);
   } /* End of popforecast */
   
   int fileappend(FILE *fichier, char *optionfich)
   {
     if((fichier=fopen(optionfich,"a"))==NULL) {
       printf("Problem with file: %s\n", optionfich);
       fprintf(ficlog,"Problem with file: %s\n", optionfich);
       return (0);
     }
     fflush(fichier);
     return (1);
   }
   
   
   /**************** function prwizard **********************/
   void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
   {
   
     /* Wizard to print covariance matrix template */
   
     char ca[32], cb[32], cc[32];
     int i,j, k, l, li, lj, lk, ll, jj, npar, itimes;
     int numlinepar;
   
     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
     fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
     for(i=1; i <=nlstate; i++){
       jj=0;
       for(j=1; j <=nlstate+ndeath; j++){
         if(j==i) continue;
         jj++;
         /*ca[0]= k+'a'-1;ca[1]='\0';*/
         printf("%1d%1d",i,j);
         fprintf(ficparo,"%1d%1d",i,j);
         for(k=1; k<=ncovmodel;k++){
           /*        printf(" %lf",param[i][j][k]); */
           /*        fprintf(ficparo," %lf",param[i][j][k]); */
           printf(" 0.");
           fprintf(ficparo," 0.");
         }
         printf("\n");
         fprintf(ficparo,"\n");
       }
     }
     printf("# Scales (for hessian or gradient estimation)\n");
     fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
     npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
     for(i=1; i <=nlstate; i++){
       jj=0;
       for(j=1; j <=nlstate+ndeath; j++){
         if(j==i) continue;
         jj++;
         fprintf(ficparo,"%1d%1d",i,j);
         printf("%1d%1d",i,j);
         fflush(stdout);
         for(k=1; k<=ncovmodel;k++){
           /*      printf(" %le",delti3[i][j][k]); */
           /*      fprintf(ficparo," %le",delti3[i][j][k]); */
           printf(" 0.");
           fprintf(ficparo," 0.");
         }
         numlinepar++;
         printf("\n");
         fprintf(ficparo,"\n");
       }
     }
     printf("# Covariance matrix\n");
   /* # 121 Var(a12)\n\ */
   /* # 122 Cov(b12,a12) Var(b12)\n\ */
   /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
   /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
   /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
   /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
   /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
   /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
     fflush(stdout);
     fprintf(ficparo,"# Covariance matrix\n");
     /* # 121 Var(a12)\n\ */
     /* # 122 Cov(b12,a12) Var(b12)\n\ */
     /* #   ...\n\ */
     /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
     
     for(itimes=1;itimes<=2;itimes++){
       jj=0;
       for(i=1; i <=nlstate; i++){
         for(j=1; j <=nlstate+ndeath; j++){
           if(j==i) continue;
           for(k=1; k<=ncovmodel;k++){
             jj++;
             ca[0]= k+'a'-1;ca[1]='\0';
             if(itimes==1){
               printf("#%1d%1d%d",i,j,k);
               fprintf(ficparo,"#%1d%1d%d",i,j,k);
             }else{
               printf("%1d%1d%d",i,j,k);
               fprintf(ficparo,"%1d%1d%d",i,j,k);
               /*  printf(" %.5le",matcov[i][j]); */
             }
             ll=0;
             for(li=1;li <=nlstate; li++){
               for(lj=1;lj <=nlstate+ndeath; lj++){
                 if(lj==li) continue;
                 for(lk=1;lk<=ncovmodel;lk++){
                   ll++;
                   if(ll<=jj){
                     cb[0]= lk +'a'-1;cb[1]='\0';
                     if(ll<jj){
                       if(itimes==1){
                         printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                         fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                       }else{
                         printf(" 0.");
                         fprintf(ficparo," 0.");
                       }
                     }else{
                       if(itimes==1){
                         printf(" Var(%s%1d%1d)",ca,i,j);
                         fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                       }else{
                         printf(" 0.");
                         fprintf(ficparo," 0.");
                       }
                     }
                   }
                 } /* end lk */
               } /* end lj */
             } /* end li */
             printf("\n");
             fprintf(ficparo,"\n");
             numlinepar++;
           } /* end k*/
         } /*end j */
       } /* end i */
     } /* end itimes */
   
   } /* end of prwizard */
   /******************* Gompertz Likelihood ******************************/
   double gompertz(double x[])
   { 
     double A,B,L=0.0,sump=0.,num=0.;
     int i,n=0; /* n is the size of the sample */
   
     for (i=0;i<=imx-1 ; i++) {
       sump=sump+weight[i];
       /*    sump=sump+1;*/
       num=num+1;
     }
    
    
     /* for (i=0; i<=imx; i++) 
        if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
   
     for (i=1;i<=imx ; i++)
       {
         if (cens[i] == 1 && wav[i]>1)
           A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
         
         if (cens[i] == 0 && wav[i]>1)
           A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
         
         /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
         if (wav[i] > 1 ) { /* ??? */
           L=L+A*weight[i];
           /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
         }
       }
   
    /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
    
     return -2*L*num/sump;
   }
   
   #ifdef GSL
   /******************* Gompertz_f Likelihood ******************************/
   double gompertz_f(const gsl_vector *v, void *params)
   { 
     double A,B,LL=0.0,sump=0.,num=0.;
     double *x= (double *) v->data;
     int i,n=0; /* n is the size of the sample */
   
     for (i=0;i<=imx-1 ; i++) {
       sump=sump+weight[i];
       /*    sump=sump+1;*/
       num=num+1;
     }
    
    
     /* for (i=0; i<=imx; i++) 
        if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
     printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
     for (i=1;i<=imx ; i++)
       {
         if (cens[i] == 1 && wav[i]>1)
           A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
         
         if (cens[i] == 0 && wav[i]>1)
           A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
         
         /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
         if (wav[i] > 1 ) { /* ??? */
           LL=LL+A*weight[i];
           /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
         }
       }
   
    /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
     printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
    
     return -2*LL*num/sump;
   }
   #endif
   
   /******************* Printing html file ***********/
   void printinghtmlmort(char fileres[], char title[], char datafile[], int firstpass, \
                     int lastpass, int stepm, int weightopt, char model[],\
                     int imx,  double p[],double **matcov,double agemortsup){
     int i,k;
   
     fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
     fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
     for (i=1;i<=2;i++) 
       fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
     fprintf(fichtm,"<br><br><img src=\"graphmort.png\">");
     fprintf(fichtm,"</ul>");
   
   fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
   
    fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
   
    for (k=agegomp;k<(agemortsup-2);k++) 
      fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
   
    
     fflush(fichtm);
   }
   
   /******************* Gnuplot file **************/
   void printinggnuplotmort(char fileres[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
   
     char dirfileres[132],optfileres[132];
     int m,cpt,k1,i,k,j,jk,k2,k3,ij,l;
     int ng;
   
   
     /*#ifdef windows */
     fprintf(ficgp,"cd \"%s\" \n",pathc);
       /*#endif */
   
   
     strcpy(dirfileres,optionfilefiname);
     strcpy(optfileres,"vpl");
     fprintf(ficgp,"set out \"graphmort.png\"\n "); 
     fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
     fprintf(ficgp, "set ter png small size 320, 240\n set log y\n"); 
     /* fprintf(ficgp, "set size 0.65,0.65\n"); */
     fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
   
   } 
   
   int readdata(char datafile[], int firstobs, int lastobs, int *imax)
   {
   
     /*-------- data file ----------*/
     FILE *fic;
     char dummy[]="                         ";
     int i, j, n;
     int linei, month, year,iout;
     char line[MAXLINE], linetmp[MAXLINE];
     char stra[80], strb[80];
     char *stratrunc;
     int lstra;
   
   
     if((fic=fopen(datafile,"r"))==NULL)    {
       printf("Problem while opening datafile: %s\n", datafile);return 1;
       fprintf(ficlog,"Problem while opening datafile: %s\n", datafile);return 1;
     }
   
     i=1;
     linei=0;
     while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
       linei=linei+1;
       for(j=strlen(line); j>=0;j--){  /* Untabifies line */
         if(line[j] == '\t')
           line[j] = ' ';
       }
       for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
         ;
       };
       line[j+1]=0;  /* Trims blanks at end of line */
       if(line[0]=='#'){
         fprintf(ficlog,"Comment line\n%s\n",line);
         printf("Comment line\n%s\n",line);
         continue;
       }
       trimbb(linetmp,line); /* Trims multiple blanks in line */
       for (j=0; line[j]!='\0';j++){
         line[j]=linetmp[j];
       }
     
   
       for (j=maxwav;j>=1;j--){
         cutv(stra, strb, line, ' '); 
         if(strb[0]=='.') { /* Missing status */
           lval=-1;
         }else{
           errno=0;
           lval=strtol(strb,&endptr,10); 
         /*        if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
           if( strb[0]=='\0' || (*endptr != '\0')){
             printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
             fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
             return 1;
           }
         }
         s[j][i]=lval;
         
         strcpy(line,stra);
         cutv(stra, strb,line,' ');
         if(iout=sscanf(strb,"%d/%d",&month, &year) != 0){
         }
         else  if(iout=sscanf(strb,"%s.",dummy) != 0){
           month=99;
           year=9999;
         }else{
           printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
           fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
           return 1;
         }
         anint[j][i]= (double) year; 
         mint[j][i]= (double)month; 
         strcpy(line,stra);
       } /* ENd Waves */
       
       cutv(stra, strb,line,' '); 
       if(iout=sscanf(strb,"%d/%d",&month, &year) != 0){
       }
       else  if(iout=sscanf(strb,"%s.",dummy) != 0){
         month=99;
         year=9999;
       }else{
         printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
           fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
           return 1;
       }
       andc[i]=(double) year; 
       moisdc[i]=(double) month; 
       strcpy(line,stra);
       
       cutv(stra, strb,line,' '); 
       if(iout=sscanf(strb,"%d/%d",&month, &year) != 0){
       }
       else  if(iout=sscanf(strb,"%s.", dummy) != 0){
         month=99;
         year=9999;
       }else{
         printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
         fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
           return 1;
       }
       if (year==9999) {
         printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
         fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
           return 1;
   
       }
       annais[i]=(double)(year);
       moisnais[i]=(double)(month); 
       strcpy(line,stra);
       
       cutv(stra, strb,line,' '); 
       errno=0;
       dval=strtod(strb,&endptr); 
       if( strb[0]=='\0' || (*endptr != '\0')){
         printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
         fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
         fflush(ficlog);
         return 1;
       }
       weight[i]=dval; 
       strcpy(line,stra);
       
       for (j=ncovcol;j>=1;j--){
         cutv(stra, strb,line,' '); 
         if(strb[0]=='.') { /* Missing status */
           lval=-1;
         }else{
           errno=0;
           lval=strtol(strb,&endptr,10); 
           if( strb[0]=='\0' || (*endptr != '\0')){
             printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
             fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
             return 1;
           }
         }
         if(lval <-1 || lval >1){
           printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
    Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
    for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
    For example, for multinomial values like 1, 2 and 3,\n \
    build V1=0 V2=0 for the reference value (1),\n \
           V1=1 V2=0 for (2) \n \
    and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
    output of IMaCh is often meaningless.\n \
    Exiting.\n",lval,linei, i,line,j);
           fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
    Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
    for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
    For example, for multinomial values like 1, 2 and 3,\n \
    build V1=0 V2=0 for the reference value (1),\n \
           V1=1 V2=0 for (2) \n \
    and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
    output of IMaCh is often meaningless.\n \
    Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
           return 1;
         }
         covar[j][i]=(double)(lval);
         strcpy(line,stra);
       }  
       lstra=strlen(stra);
        
       if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
         stratrunc = &(stra[lstra-9]);
         num[i]=atol(stratrunc);
       }
       else
         num[i]=atol(stra);
       /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
         printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
       
       i=i+1;
     } /* End loop reading  data */
   
     *imax=i-1; /* Number of individuals */
     fclose(fic);
    
     return (0);
     endread:
       printf("Exiting readdata: ");
       fclose(fic);
       return (1);
   
   
   
   }
   void removespace(char *str) {
     char *p1 = str, *p2 = str;
     do
       while (*p2 == ' ')
         p2++;
     while (*p1++ = *p2++);
   }
   
   int decodemodel ( char model[], int lastobs) /**< This routine decode the model and returns:
      * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age
      * - cptcovt total number of covariates of the model nbocc(+)+1 = 8
      * - cptcovn or number of covariates k of the models excluding age*products =6
      * - cptcovage number of covariates with age*products =2
      * - cptcovs number of simple covariates
      * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
      *     which is a new column after the 9 (ncovcol) variables. 
      * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
      * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
      *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
      * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
    */
   {
     int i, j, k, ks;
     int i1, j1, k1, k2;
     char modelsav[80];
     char stra[80], strb[80], strc[80], strd[80],stre[80];
   
     /*removespace(model);*/
     if (strlen(model) >1){ /* If there is at least 1 covariate */
       j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
       j=nbocc(model,'+'); /**< j=Number of '+' */
       j1=nbocc(model,'*'); /**< j1=Number of '*' */
       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V2*age+V3 +V3*V4=> V1 + V3 =2  */
       cptcovt= j+1; /* Number of total covariates in the model V1 + V2*age+ V3 + V3*V4=> 4*/
                     /* including age products which are counted in cptcovage.
                     /* but the covariates which are products must be treated separately: ncovn=4- 2=2 (V1+V3). */
       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
       strcpy(modelsav,model); 
       if (strstr(model,"AGE") !=0){
         printf("Error. AGE must be in lower case 'age' model=%s ",model);
         fprintf(ficlog,"Error. AGE must be in lower case model=%s ",model);fflush(ficlog);
         return 1;
       }
       if (strstr(model,"v") !=0){
         printf("Error. 'v' must be in upper case 'V' model=%s ",model);
         fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
         return 1;
       }
       
       /*   Design
        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
        *  <          ncovcol=8                >
        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
        *   k=  1    2      3       4     5       6      7        8
        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
        *  covar[k,i], value of kth covariate if not including age for individual i:
        *       covar[1][i]= (V2), covar[4][i]=(V3), covar[8][i]=(V8)
        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[4]=3 Tvar[8]=8
        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
        *  Tage[++cptcovage]=k
        *       if products, new covar are created after ncovcol with k1
        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
        *  <          ncovcol=8                >
        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
        * p Tprod[1]@2={                         6, 5}
        *p Tvard[1][1]@4= {7, 8, 5, 6}
        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
        *How to reorganize?
        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
        *       {2,   1,     4,      8,    5,      6,     3,       7}
        * Struct []
        */
   
       /* This loop fills the array Tvar from the string 'model'.*/
       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
       /*  k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
       /*  k=3 V4 Tvar[k=3]= 4 (from V4) */
       /*  k=2 V1 Tvar[k=2]= 1 (from V1) */
       /*  k=1 Tvar[1]=2 (from V2) */
       /*  k=5 Tvar[5] */
       /* for (k=1; k<=cptcovn;k++) { */
       /*  cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]]; */
       /*  } */
       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
       /*
        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
       for(k=cptcovt; k>=1;k--) /**< Number of covariates */
           Tvar[k]=0;
       cptcovage=0;
       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
         cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
                                        modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
         if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
         /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
         /*scanf("%d",i);*/
         if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
           cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
           if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
             /* covar is not filled and then is empty */
             cptcovprod--;
             cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
             Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2 */
             cptcovage++; /* Sums the number of covariates which include age as a product */
             Tage[cptcovage]=k;  /* Tage[1] = 4 */
             /*printf("stre=%s ", stre);*/
           } else if (strcmp(strd,"age")==0) { /* or age*Vn */
             cptcovprod--;
             cutl(stre,strb,strc,'V');
             Tvar[k]=atoi(stre);
             cptcovage++;
             Tage[cptcovage]=k;
           } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
             /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
             cptcovn++;
             cptcovprodnoage++;k1++;
             cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
             Tvar[k]=ncovcol+k1; /* For model-covariate k tells which data-covariate to use but
                                     because this model-covariate is a construction we invent a new column
                                     ncovcol + k1
                                     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                                     Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
             cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
             Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
             Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
             Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
             k2=k2+2;
             Tvar[cptcovt+k2]=Tvard[k1][1]; /* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) */
             Tvar[cptcovt+k2+1]=Tvard[k1][2];  /* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) */
             for (i=1; i<=lastobs;i++){
               /* Computes the new covariate which is a product of
                  covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
               covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
             }
           } /* End age is not in the model */
         } /* End if model includes a product */
         else { /* no more sum */
           /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
          /*  scanf("%d",i);*/
           cutl(strd,strc,strb,'V');
           ks++; /**< Number of simple covariates */
           cptcovn++;
           Tvar[k]=atoi(strd);
         }
         strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
         /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
           scanf("%d",i);*/
       } /* end of loop + */
     } /* end model */
     
     /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
       If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
   
     /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
     printf("cptcovprod=%d ", cptcovprod);
     fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
   
     scanf("%d ",i);*/
   
   
     return (0); /* with covar[new additional covariate if product] and Tage if age */ 
     endread:
       printf("Exiting decodemodel: ");
       return (1);
   }
   
   calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
   {
     int i, m;
   
     for (i=1; i<=imx; i++) {
       for(m=2; (m<= maxwav); m++) {
         if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
           anint[m][i]=9999;
           s[m][i]=-1;
         }
         if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
           *nberr++;
           printf("Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results are biased\n",(int)moisdc[i],(int)andc[i],num[i],i);
           fprintf(ficlog,"Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results are biased\n",(int)moisdc[i],(int)andc[i],num[i],i);
           s[m][i]=-1;
         }
         if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
           *nberr++;
           printf("Error! Month of death of individual %ld on line %d was unknown %2d, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,(int)moisdc[i]); 
           fprintf(ficlog,"Error! Month of death of individual %ld on line %d was unknown %f, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,moisdc[i]); 
           s[m][i]=-1; /* We prefer to skip it (and to skip it in version 0.8a1 too */
         }
       }
     }
   
     for (i=1; i<=imx; i++)  {
       agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
       for(m=firstpass; (m<= lastpass); m++){
         if(s[m][i] >0 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){
           if (s[m][i] >= nlstate+1) {
             if(agedc[i]>0)
               if((int)moisdc[i]!=99 && (int)andc[i]!=9999)
                 agev[m][i]=agedc[i];
             /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
               else {
                 if ((int)andc[i]!=9999){
                   nbwarn++;
                   printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   agev[m][i]=-1;
                 }
               }
           }
           else if(s[m][i] !=9){ /* Standard case, age in fractional
                                    years but with the precision of a month */
             agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
             if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
               agev[m][i]=1;
             else if(agev[m][i] < *agemin){ 
               *agemin=agev[m][i];
               printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
             }
             else if(agev[m][i] >*agemax){
               *agemax=agev[m][i];
               /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
             }
             /*agev[m][i]=anint[m][i]-annais[i];*/
             /*     agev[m][i] = age[i]+2*m;*/
           }
           else { /* =9 */
             agev[m][i]=1;
             s[m][i]=-1;
           }
         }
         else /*= 0 Unknown */
           agev[m][i]=1;
       }
       
     }
     for (i=1; i<=imx; i++)  {
       for(m=firstpass; (m<=lastpass); m++){
         if (s[m][i] > (nlstate+ndeath)) {
           *nberr++;
           printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
           fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
           return 1;
         }
       }
     }
   
     /*for (i=1; i<=imx; i++){
     for (m=firstpass; (m<lastpass); m++){
        printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
   }
   
   }*/
   
   
     printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
     fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
   
     return (0);
     endread:
       printf("Exiting calandcheckages: ");
       return (1);
   }
   
   
   /***********************************************/
   /**************** Main Program *****************/
   /***********************************************/
   
   int main(int argc, char *argv[])
   {
   #ifdef GSL
     const gsl_multimin_fminimizer_type *T;
     size_t iteri = 0, it;
     int rval = GSL_CONTINUE;
     int status = GSL_SUCCESS;
     double ssval;
   #endif
     int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
     int i,j, k, n=MAXN,iter,m,size=100,cptcode, cptcod;
     int linei, month, year,iout;
     int jj, ll, li, lj, lk, imk;
     int numlinepar=0; /* Current linenumber of parameter file */
     int itimes;
     int NDIM=2;
     int vpopbased=0;
   
     char ca[32], cb[32], cc[32];
     /*  FILE *fichtm; *//* Html File */
     /* FILE *ficgp;*/ /*Gnuplot File */
     struct stat info;
     double agedeb, agefin,hf;
     double ageminpar=1.e20,agemin=1.e20, agemaxpar=-1.e20, agemax=-1.e20;
   
     double fret;
     double **xi,tmp,delta;
   
     double dum; /* Dummy variable */
     double ***p3mat;
     double ***mobaverage;
     int *indx;
     char line[MAXLINE], linepar[MAXLINE];
     char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE],model[MAXLINE];
     char pathr[MAXLINE], pathimach[MAXLINE]; 
     char **bp, *tok, *val; /* pathtot */
     int firstobs=1, lastobs=10;
     int sdeb, sfin; /* Status at beginning and end */
     int c,  h , cpt,l;
     int ju,jl, mi;
     int i1,j1, jk,aa,bb, stepsize, ij;
     int jnais,jdc,jint4,jint1,jint2,jint3,*tab; 
     int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
     int mobilav=0,popforecast=0;
     int hstepm, nhstepm;
     int agemortsup;
     float  sumlpop=0.;
     double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
     double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
   
     double bage, fage, age, agelim, agebase;
     double ftolpl=FTOL;
     double **prlim;
     double ***param; /* Matrix of parameters */
     double  *p;
     double **matcov; /* Matrix of covariance */
     double ***delti3; /* Scale */
     double *delti; /* Scale */
     double ***eij, ***vareij;
     double **varpl; /* Variances of prevalence limits by age */
     double *epj, vepp;
     double kk1, kk2;
     double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
     double **ximort;
     char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
     int *dcwave;
   
     char z[1]="c", occ;
   
     /*char  *strt;*/
     char strtend[80];
   
     long total_usecs;
    
   /*   setlocale (LC_ALL, ""); */
   /*   bindtextdomain (PACKAGE, LOCALEDIR); */
   /*   textdomain (PACKAGE); */
   /*   setlocale (LC_CTYPE, ""); */
   /*   setlocale (LC_MESSAGES, ""); */
   
     /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
     rstart_time = time(NULL);  
     /*  (void) gettimeofday(&start_time,&tzp);*/
     start_time = *localtime(&rstart_time);
     curr_time=start_time;
     /*tml = *localtime(&start_time.tm_sec);*/
     /* strcpy(strstart,asctime(&tml)); */
     strcpy(strstart,asctime(&start_time));
   
   /*  printf("Localtime (at start)=%s",strstart); */
   /*  tp.tm_sec = tp.tm_sec +86400; */
   /*  tm = *localtime(&start_time.tm_sec); */
   /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
   /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
   /*   tmg.tm_hour=tmg.tm_hour + 1; */
   /*   tp.tm_sec = mktime(&tmg); */
   /*   strt=asctime(&tmg); */
   /*   printf("Time(after) =%s",strstart);  */
   /*  (void) time (&time_value);
   *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
   *  tm = *localtime(&time_value);
   *  strstart=asctime(&tm);
   *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
   */
   
     nberr=0; /* Number of errors and warnings */
     nbwarn=0;
     getcwd(pathcd, size);
   
     printf("\n%s\n%s",version,fullversion);
     if(argc <=1){
       printf("\nEnter the parameter file name: ");
       fgets(pathr,FILENAMELENGTH,stdin);
       i=strlen(pathr);
       if(pathr[i-1]=='\n')
         pathr[i-1]='\0';
       i=strlen(pathr);
       if(pathr[i-1]==' ') /* This may happen when dragging on oS/X! */
         pathr[i-1]='\0';
      for (tok = pathr; tok != NULL; ){
         printf("Pathr |%s|\n",pathr);
         while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
         printf("val= |%s| pathr=%s\n",val,pathr);
         strcpy (pathtot, val);
         if(pathr[0] == '\0') break; /* Dirty */
       }
     }
     else{
       strcpy(pathtot,argv[1]);
     }
     /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
     /*cygwin_split_path(pathtot,path,optionfile);
       printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
     /* cutv(path,optionfile,pathtot,'\\');*/
   
     /* Split argv[0], imach program to get pathimach */
     printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
     split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
     printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
    /*   strcpy(pathimach,argv[0]); */
     /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
     split(pathtot,path,optionfile,optionfilext,optionfilefiname);
     printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
     chdir(path); /* Can be a relative path */
     if(getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
       printf("Current directory %s!\n",pathcd);
     strcpy(command,"mkdir ");
     strcat(command,optionfilefiname);
     if((outcmd=system(command)) != 0){
       printf("Problem creating directory or it already exists %s%s, err=%d\n",path,optionfilefiname,outcmd);
       /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
       /* fclose(ficlog); */
   /*     exit(1); */
     }
   /*   if((imk=mkdir(optionfilefiname))<0){ */
   /*     perror("mkdir"); */
   /*   } */
   
     /*-------- arguments in the command line --------*/
   
     /* Log file */
     strcat(filelog, optionfilefiname);
     strcat(filelog,".log");    /* */
     if((ficlog=fopen(filelog,"w"))==NULL)    {
       printf("Problem with logfile %s\n",filelog);
       goto end;
     }
     fprintf(ficlog,"Log filename:%s\n",filelog);
     fprintf(ficlog,"\n%s\n%s",version,fullversion);
     fprintf(ficlog,"\nEnter the parameter file name: \n");
     fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
    path=%s \n\
    optionfile=%s\n\
    optionfilext=%s\n\
    optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
   
     printf("Local time (at start):%s",strstart);
     fprintf(ficlog,"Local time (at start): %s",strstart);
     fflush(ficlog);
   /*   (void) gettimeofday(&curr_time,&tzp); */
   /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
   
     /* */
     strcpy(fileres,"r");
     strcat(fileres, optionfilefiname);
     strcat(fileres,".txt");    /* Other files have txt extension */
   
     /*---------arguments file --------*/
   
     if((ficpar=fopen(optionfile,"r"))==NULL)    {
       printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
       fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
       fflush(ficlog);
       /* goto end; */
       exit(70); 
     }
   
   
   
     strcpy(filereso,"o");
     strcat(filereso,fileres);
     if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
       printf("Problem with Output resultfile: %s\n", filereso);
       fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
       fflush(ficlog);
       goto end;
     }
   
     /* Reads comments: lines beginning with '#' */
     numlinepar=0;
     while((c=getc(ficpar))=='#' && c!= EOF){
       ungetc(c,ficpar);
       fgets(line, MAXLINE, ficpar);
       numlinepar++;
       fputs(line,stdout);
       fputs(line,ficparo);
       fputs(line,ficlog);
     }
     ungetc(c,ficpar);
   
     fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model);
     numlinepar++;
     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model);
     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model);
     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model);
     fflush(ficlog);
     while((c=getc(ficpar))=='#' && c!= EOF){
       ungetc(c,ficpar);
       fgets(line, MAXLINE, ficpar);
       numlinepar++;
       fputs(line, stdout);
       //puts(line);
       fputs(line,ficparo);
       fputs(line,ficlog);
     }
     ungetc(c,ficpar);
   
      
     covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
     cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
     /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
        v1+v2*age+v2*v3 makes cptcovn = 3
     */
     if (strlen(model)>1) 
       ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7*/
     else
       ncovmodel=2;
     nvar=ncovmodel-1; /* Suppressing age as a basic covariate */
     nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
     npar= nforce*ncovmodel; /* Number of parameters like aij*/
     if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
       printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
       fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
       fflush(stdout);
       fclose (ficlog);
       goto end;
     }
     delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
     delti=delti3[1][1];
     /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
     if(mle==-1){ /* Print a wizard for help writing covariance matrix */
       prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
       printf(" You choose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
       fprintf(ficlog," You choose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
       free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
       fclose (ficparo);
       fclose (ficlog);
       goto end;
       exit(0);
     }
     else if(mle==-3) {
       prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
       printf(" You choose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
       fprintf(ficlog," You choose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
       param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
       matcov=matrix(1,npar,1,npar);
     }
     else{
       /* Read guessed parameters */
       /* Reads comments: lines beginning with '#' */
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         numlinepar++;
         fputs(line,stdout);
         fputs(line,ficparo);
         fputs(line,ficlog);
       }
       ungetc(c,ficpar);
       
       param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
       for(i=1; i <=nlstate; i++){
         j=0;
         for(jj=1; jj <=nlstate+ndeath; jj++){
           if(jj==i) continue;
           j++;
           fscanf(ficpar,"%1d%1d",&i1,&j1);
           if ((i1 != i) && (j1 != j)){
             printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
   It might be a problem of design; if ncovcol and the model are correct\n \
   run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
             exit(1);
           }
           fprintf(ficparo,"%1d%1d",i1,j1);
           if(mle==1)
             printf("%1d%1d",i,j);
           fprintf(ficlog,"%1d%1d",i,j);
           for(k=1; k<=ncovmodel;k++){
             fscanf(ficpar," %lf",&param[i][j][k]);
             if(mle==1){
               printf(" %lf",param[i][j][k]);
               fprintf(ficlog," %lf",param[i][j][k]);
             }
             else
               fprintf(ficlog," %lf",param[i][j][k]);
             fprintf(ficparo," %lf",param[i][j][k]);
           }
           fscanf(ficpar,"\n");
           numlinepar++;
           if(mle==1)
             printf("\n");
           fprintf(ficlog,"\n");
           fprintf(ficparo,"\n");
         }
       }  
       fflush(ficlog);
   
       /* Reads scales values */
       p=param[1][1];
       
       /* Reads comments: lines beginning with '#' */
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         numlinepar++;
         fputs(line,stdout);
         fputs(line,ficparo);
         fputs(line,ficlog);
       }
       ungetc(c,ficpar);
   
       for(i=1; i <=nlstate; i++){
         for(j=1; j <=nlstate+ndeath-1; j++){
           fscanf(ficpar,"%1d%1d",&i1,&j1);
           if ((i1-i)*(j1-j)!=0){
             printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
             exit(1);
           }
           printf("%1d%1d",i,j);
           fprintf(ficparo,"%1d%1d",i1,j1);
           fprintf(ficlog,"%1d%1d",i1,j1);
           for(k=1; k<=ncovmodel;k++){
             fscanf(ficpar,"%le",&delti3[i][j][k]);
             printf(" %le",delti3[i][j][k]);
             fprintf(ficparo," %le",delti3[i][j][k]);
             fprintf(ficlog," %le",delti3[i][j][k]);
           }
           fscanf(ficpar,"\n");
           numlinepar++;
           printf("\n");
           fprintf(ficparo,"\n");
           fprintf(ficlog,"\n");
         }
       }
       fflush(ficlog);
   
       /* Reads covariance matrix */
       delti=delti3[1][1];
   
   
       /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
     
       /* Reads comments: lines beginning with '#' */
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         numlinepar++;
         fputs(line,stdout);
         fputs(line,ficparo);
         fputs(line,ficlog);
       }
       ungetc(c,ficpar);
     
       matcov=matrix(1,npar,1,npar);
       for(i=1; i <=npar; i++)
         for(j=1; j <=npar; j++) matcov[i][j]=0.;
         
       for(i=1; i <=npar; i++){
         fscanf(ficpar,"%s",str);
         if(mle==1)
           printf("%s",str);
         fprintf(ficlog,"%s",str);
         fprintf(ficparo,"%s",str);
         for(j=1; j <=i; j++){
           fscanf(ficpar," %le",&matcov[i][j]);
           if(mle==1){
             printf(" %.5le",matcov[i][j]);
           }
           fprintf(ficlog," %.5le",matcov[i][j]);
           fprintf(ficparo," %.5le",matcov[i][j]);
         }
         fscanf(ficpar,"\n");
         numlinepar++;
         if(mle==1)
           printf("\n");
         fprintf(ficlog,"\n");
         fprintf(ficparo,"\n");
       }
       for(i=1; i <=npar; i++)
         for(j=i+1;j<=npar;j++)
           matcov[i][j]=matcov[j][i];
       
       if(mle==1)
         printf("\n");
       fprintf(ficlog,"\n");
       
       fflush(ficlog);
       
       /*-------- Rewriting parameter file ----------*/
       strcpy(rfileres,"r");    /* "Rparameterfile */
       strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
       strcat(rfileres,".");    /* */
       strcat(rfileres,optionfilext);    /* Other files have txt extension */
       if((ficres =fopen(rfileres,"w"))==NULL) {
         printf("Problem writing new parameter file: %s\n", fileres);goto end;
         fprintf(ficlog,"Problem writing new parameter file: %s\n", fileres);goto end;
       }
       fprintf(ficres,"#%s\n",version);
     }    /* End of mle != -3 */
   
   
     n= lastobs;
     num=lvector(1,n);
     moisnais=vector(1,n);
     annais=vector(1,n);
     moisdc=vector(1,n);
     andc=vector(1,n);
     agedc=vector(1,n);
     cod=ivector(1,n);
     weight=vector(1,n);
     for(i=1;i<=n;i++) weight[i]=1.0; /* Equal weights, 1 by default */
     mint=matrix(1,maxwav,1,n);
     anint=matrix(1,maxwav,1,n);
     s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
     tab=ivector(1,NCOVMAX);
     ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
   
     /* Reads data from file datafile */
     if (readdata(datafile, firstobs, lastobs, &imx)==1)
       goto end;
   
     /* Calculation of the number of parameters from char model */
       /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
           k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
           k=3 V4 Tvar[k=3]= 4 (from V4)
           k=2 V1 Tvar[k=2]= 1 (from V1)
           k=1 Tvar[1]=2 (from V2)
       */
     Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
     /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
         For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
         Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
     */
     /* For model-covariate k tells which data-covariate to use but
       because this model-covariate is a construction we invent a new column
       ncovcol + k1
       If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
       Tvar[3=V1*V4]=4+1 etc */
     Tprod=ivector(1,NCOVMAX); /* Gives the position of a product */
     /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
        if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
     */
     Tvaraff=ivector(1,NCOVMAX); /* Unclear */
     Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
                               * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                               * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
     Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
                            4 covariates (3 plus signs)
                            Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                         */  
   
     if(decodemodel(model, lastobs) == 1)
       goto end;
   
     if((double)(lastobs-imx)/(double)imx > 1.10){
       nbwarn++;
       printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
       fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
     }
       /*  if(mle==1){*/
     if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
       for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
     }
   
       /*-calculation of age at interview from date of interview and age at death -*/
     agev=matrix(1,maxwav,1,imx);
   
     if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
       goto end;
   
   
     agegomp=(int)agemin;
     free_vector(moisnais,1,n);
     free_vector(annais,1,n);
     /* free_matrix(mint,1,maxwav,1,n);
        free_matrix(anint,1,maxwav,1,n);*/
     free_vector(moisdc,1,n);
     free_vector(andc,1,n);
     /* */
     
     wav=ivector(1,imx);
     dh=imatrix(1,lastpass-firstpass+1,1,imx);
     bh=imatrix(1,lastpass-firstpass+1,1,imx);
     mw=imatrix(1,lastpass-firstpass+1,1,imx);
      
     /* Concatenates waves */
     concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
     /* */
    
     /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
   
     nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
     ncodemax[1]=1;
     Ndum =ivector(-1,NCOVMAX);  
     if (ncovmodel > 2)
       tricode(Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
   
     codtab=imatrix(1,100,1,10); /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
     /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtab[100][10]);*/
     h=0;
   
   
     /*if (cptcovn > 0) */
         
    
     m=pow(2,cptcoveff);
    
     for(k=1;k<=cptcoveff; k++){ /* scans any effective covariate */
       for(i=1; i <=pow(2,cptcoveff-k);i++){ /* i=1 to 8/1=8; i=1 to 8/2=4; i=1 to 8/8=1 */ 
         for(j=1; j <= ncodemax[k]; j++){ /* For each modality of this covariate ncodemax=2*/
           for(cpt=1; cpt <=pow(2,k-1); cpt++){  /* cpt=1 to 8/2**(3+1-1 or 3+1-3) =1 or 4 */ 
             h++;
             if (h>m) 
               h=1;
             /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
              *     h     1     2     3     4
              *______________________________  
              *     1 i=1 1 i=1 1 i=1 1 i=1 1
              *     2     2     1     1     1
              *     3 i=2 1     2     1     1
              *     4     2     2     1     1
              *     5 i=3 1 i=2 1     2     1
              *     6     2     1     2     1
              *     7 i=4 1     2     2     1
              *     8     2     2     2     1
              *     9 i=5 1 i=3 1 i=2 1     1
              *    10     2     1     1     1
              *    11 i=6 1     2     1     1
              *    12     2     2     1     1
              *    13 i=7 1 i=4 1     2     1    
              *    14     2     1     2     1
              *    15 i=8 1     2     2     1
              *    16     2     2     2     1
              */
             codtab[h][k]=j;
             /*codtab[h][Tvar[k]]=j;*/
             printf("h=%d k=%d j=%d codtab[h][k]=%d Tvar[k]=%d codtab[h][Tvar[k]]=%d \n",h, k,j,codtab[h][k],Tvar[k],codtab[h][Tvar[k]]);
           } 
         }
       }
     } 
     /* printf("codtab[1][2]=%d codtab[2][2]=%d",codtab[1][2],codtab[2][2]); 
        codtab[1][2]=1;codtab[2][2]=2; */
     /* for(i=1; i <=m ;i++){ 
        for(k=1; k <=cptcovn; k++){
          printf("i=%d k=%d %d %d ",i,k,codtab[i][k], cptcoveff);
        }
        printf("\n");
        }
        scanf("%d",i);*/
   
    free_ivector(Ndum,-1,NCOVMAX);
   
   
       
     /*------------ gnuplot -------------*/
     strcpy(optionfilegnuplot,optionfilefiname);
     if(mle==-3)
       strcat(optionfilegnuplot,"-mort");
     strcat(optionfilegnuplot,".gp");
   
     if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
       printf("Problem with file %s",optionfilegnuplot);
     }
     else{
       fprintf(ficgp,"\n# %s\n", version); 
       fprintf(ficgp,"# %s\n", optionfilegnuplot); 
       //fprintf(ficgp,"set missing 'NaNq'\n");
       fprintf(ficgp,"set datafile missing 'NaNq'\n");
     }
     /*  fclose(ficgp);*/
     /*--------- index.htm --------*/
   
     strcpy(optionfilehtm,optionfilefiname); /* Main html file */
     if(mle==-3)
       strcat(optionfilehtm,"-mort");
     strcat(optionfilehtm,".htm");
     if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
       printf("Problem with %s \n",optionfilehtm);
       exit(0);
     }
   
     strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
     strcat(optionfilehtmcov,"-cov.htm");
     if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
       printf("Problem with %s \n",optionfilehtmcov), exit(0);
     }
     else{
     fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
   <hr size=\"2\" color=\"#EC5E5E\"> \n\
   Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=%s<br>\n",\
             optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
     }
   
     fprintf(fichtm,"<html><head>\n<title>IMaCh %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
   <hr size=\"2\" color=\"#EC5E5E\"> \n\
   Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=%s<br>\n\
   \n\
   <hr  size=\"2\" color=\"#EC5E5E\">\
    <ul><li><h4>Parameter files</h4>\n\
    - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
    - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
    - Log file of the run: <a href=\"%s\">%s</a><br>\n\
    - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
    - Date and time at start: %s</ul>\n",\
             optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
             optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
             fileres,fileres,\
             filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
     fflush(fichtm);
   
     strcpy(pathr,path);
     strcat(pathr,optionfilefiname);
     chdir(optionfilefiname); /* Move to directory named optionfile */
     
     /* Calculates basic frequencies. Computes observed prevalence at single age
        and prints on file fileres'p'. */
     freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart);
   
     fprintf(fichtm,"\n");
     fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
   Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
   Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
             imx,agemin,agemax,jmin,jmax,jmean);
     pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
       
      
     /* For Powell, parameters are in a vector p[] starting at p[1]
        so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
     p=param[1][1]; /* *(*(*(param +1)+1)+0) */
   
     globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
   
     if (mle==-3){
       ximort=matrix(1,NDIM,1,NDIM); 
   /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
       cens=ivector(1,n);
       ageexmed=vector(1,n);
       agecens=vector(1,n);
       dcwave=ivector(1,n);
    
       for (i=1; i<=imx; i++){
         dcwave[i]=-1;
         for (m=firstpass; m<=lastpass; m++)
           if (s[m][i]>nlstate) {
             dcwave[i]=m;
             /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
             break;
           }
       }
   
       for (i=1; i<=imx; i++) {
         if (wav[i]>0){
           ageexmed[i]=agev[mw[1][i]][i];
           j=wav[i];
           agecens[i]=1.; 
   
           if (ageexmed[i]> 1 && wav[i] > 0){
             agecens[i]=agev[mw[j][i]][i];
             cens[i]= 1;
           }else if (ageexmed[i]< 1) 
             cens[i]= -1;
           if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
             cens[i]=0 ;
         }
         else cens[i]=-1;
       }
       
       for (i=1;i<=NDIM;i++) {
         for (j=1;j<=NDIM;j++)
           ximort[i][j]=(i == j ? 1.0 : 0.0);
       }
       
       /*p[1]=0.0268; p[NDIM]=0.083;*/
       /*printf("%lf %lf", p[1], p[2]);*/
       
       
   #ifdef GSL
       printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
   #elsedef
       printf("Powell\n");  fprintf(ficlog,"Powell\n");
   #endif
       strcpy(filerespow,"pow-mort"); 
       strcat(filerespow,fileres);
       if((ficrespow=fopen(filerespow,"w"))==NULL) {
         printf("Problem with resultfile: %s\n", filerespow);
         fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
       }
   #ifdef GSL
       fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
   #elsedef
       fprintf(ficrespow,"# Powell\n# iter -2*LL");
   #endif
       /*  for (i=1;i<=nlstate;i++)
           for(j=1;j<=nlstate+ndeath;j++)
           if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
       */
       fprintf(ficrespow,"\n");
   #ifdef GSL
       /* gsl starts here */ 
       T = gsl_multimin_fminimizer_nmsimplex;
       gsl_multimin_fminimizer *sfm = NULL;
       gsl_vector *ss, *x;
       gsl_multimin_function minex_func;
   
       /* Initial vertex size vector */
       ss = gsl_vector_alloc (NDIM);
       
       if (ss == NULL){
         GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
       }
       /* Set all step sizes to 1 */
       gsl_vector_set_all (ss, 0.001);
   
       /* Starting point */
       
       x = gsl_vector_alloc (NDIM);
       
       if (x == NULL){
         gsl_vector_free(ss);
         GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
       }
     
       /* Initialize method and iterate */
       /*     p[1]=0.0268; p[NDIM]=0.083; */
   /*     gsl_vector_set(x, 0, 0.0268); */
   /*     gsl_vector_set(x, 1, 0.083); */
       gsl_vector_set(x, 0, p[1]);
       gsl_vector_set(x, 1, p[2]);
   
       minex_func.f = &gompertz_f;
       minex_func.n = NDIM;
       minex_func.params = (void *)&p; /* ??? */
       
       sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
       gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
       
       printf("Iterations beginning .....\n\n");
       printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
   
       iteri=0;
       while (rval == GSL_CONTINUE){
         iteri++;
         status = gsl_multimin_fminimizer_iterate(sfm);
         
         if (status) printf("error: %s\n", gsl_strerror (status));
         fflush(0);
         
         if (status) 
           break;
         
         rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
         ssval = gsl_multimin_fminimizer_size (sfm);
         
         if (rval == GSL_SUCCESS)
           printf ("converged to a local maximum at\n");
         
         printf("%5d ", iteri);
         for (it = 0; it < NDIM; it++){
           printf ("%10.5f ", gsl_vector_get (sfm->x, it));
         }
         printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
       }
       
       printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
       
       gsl_vector_free(x); /* initial values */
       gsl_vector_free(ss); /* inital step size */
       for (it=0; it<NDIM; it++){
         p[it+1]=gsl_vector_get(sfm->x,it);
         fprintf(ficrespow," %.12lf", p[it]);
       }
       gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
   #endif
   #ifdef POWELL
        powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
   #endif  
       fclose(ficrespow);
       
       hesscov(matcov, p, NDIM, delti, 1e-4, gompertz); 
   
       for(i=1; i <=NDIM; i++)
         for(j=i+1;j<=NDIM;j++)
           matcov[i][j]=matcov[j][i];
       
       printf("\nCovariance matrix\n ");
       for(i=1; i <=NDIM; i++) {
         for(j=1;j<=NDIM;j++){ 
           printf("%f ",matcov[i][j]);
         }
         printf("\n ");
       }
       
       printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
       for (i=1;i<=NDIM;i++) 
         printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
   
       lsurv=vector(1,AGESUP);
       lpop=vector(1,AGESUP);
       tpop=vector(1,AGESUP);
       lsurv[agegomp]=100000;
       
       for (k=agegomp;k<=AGESUP;k++) {
         agemortsup=k;
         if (p[1]*exp(p[2]*(k-agegomp))>1) break;
       }
       
       for (k=agegomp;k<agemortsup;k++)
         lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
       
       for (k=agegomp;k<agemortsup;k++){
         lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
         sumlpop=sumlpop+lpop[k];
       }
       
       tpop[agegomp]=sumlpop;
       for (k=agegomp;k<(agemortsup-3);k++){
         /*  tpop[k+1]=2;*/
         tpop[k+1]=tpop[k]-lpop[k];
       }
       
       
       printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
       for (k=agegomp;k<(agemortsup-2);k++) 
         printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
       
       
       replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
       printinggnuplotmort(fileres, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
       
       printinghtmlmort(fileres,title,datafile, firstpass, lastpass, \
                        stepm, weightopt,\
                        model,imx,p,matcov,agemortsup);
       
       free_vector(lsurv,1,AGESUP);
       free_vector(lpop,1,AGESUP);
       free_vector(tpop,1,AGESUP);
   #ifdef GSL
       free_ivector(cens,1,n);
       free_vector(agecens,1,n);
       free_ivector(dcwave,1,n);
       free_matrix(ximort,1,NDIM,1,NDIM);
   #endif
     } /* Endof if mle==-3 */
     
     else{ /* For mle >=1 */
       globpr=0;/* debug */
       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
       printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
       for (k=1; k<=npar;k++)
         printf(" %d %8.5f",k,p[k]);
       printf("\n");
       globpr=1; /* to print the contributions */
       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
       printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
       for (k=1; k<=npar;k++)
         printf(" %d %8.5f",k,p[k]);
       printf("\n");
       if(mle>=1){ /* Could be 1 or 2 */
         mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
       }
       
       /*--------- results files --------------*/
       fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate, ndeath, maxwav, weightopt,model);
       
       
       fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
       printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
       fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
       for(i=1,jk=1; i <=nlstate; i++){
         for(k=1; k <=(nlstate+ndeath); k++){
           if (k != i) {
             printf("%d%d ",i,k);
             fprintf(ficlog,"%d%d ",i,k);
             fprintf(ficres,"%1d%1d ",i,k);
             for(j=1; j <=ncovmodel; j++){
               printf("%lf ",p[jk]);
               fprintf(ficlog,"%lf ",p[jk]);
               fprintf(ficres,"%lf ",p[jk]);
               jk++; 
             }
             printf("\n");
             fprintf(ficlog,"\n");
             fprintf(ficres,"\n");
           }
         }
       }
       if(mle!=0){
         /* Computing hessian and covariance matrix */
         ftolhess=ftol; /* Usually correct */
         hesscov(matcov, p, npar, delti, ftolhess, func);
       }
       fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
       printf("# Scales (for hessian or gradient estimation)\n");
       fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
       for(i=1,jk=1; i <=nlstate; i++){
         for(j=1; j <=nlstate+ndeath; j++){
           if (j!=i) {
             fprintf(ficres,"%1d%1d",i,j);
             printf("%1d%1d",i,j);
             fprintf(ficlog,"%1d%1d",i,j);
             for(k=1; k<=ncovmodel;k++){
               printf(" %.5e",delti[jk]);
               fprintf(ficlog," %.5e",delti[jk]);
               fprintf(ficres," %.5e",delti[jk]);
               jk++;
             }
             printf("\n");
             fprintf(ficlog,"\n");
             fprintf(ficres,"\n");
           }
         }
       }
       
       fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
       if(mle>=1)
         printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
       fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
       /* # 121 Var(a12)\n\ */
       /* # 122 Cov(b12,a12) Var(b12)\n\ */
       /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
       /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
       /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
       /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
       /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
       /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
       
       
       /* Just to have a covariance matrix which will be more understandable
          even is we still don't want to manage dictionary of variables
       */
       for(itimes=1;itimes<=2;itimes++){
         jj=0;
         for(i=1; i <=nlstate; i++){
           for(j=1; j <=nlstate+ndeath; j++){
             if(j==i) continue;
             for(k=1; k<=ncovmodel;k++){
               jj++;
               ca[0]= k+'a'-1;ca[1]='\0';
               if(itimes==1){
                 if(mle>=1)
                   printf("#%1d%1d%d",i,j,k);
                 fprintf(ficlog,"#%1d%1d%d",i,j,k);
                 fprintf(ficres,"#%1d%1d%d",i,j,k);
               }else{
                 if(mle>=1)
                   printf("%1d%1d%d",i,j,k);
                 fprintf(ficlog,"%1d%1d%d",i,j,k);
                 fprintf(ficres,"%1d%1d%d",i,j,k);
               }
               ll=0;
               for(li=1;li <=nlstate; li++){
                 for(lj=1;lj <=nlstate+ndeath; lj++){
                   if(lj==li) continue;
                   for(lk=1;lk<=ncovmodel;lk++){
                     ll++;
                     if(ll<=jj){
                       cb[0]= lk +'a'-1;cb[1]='\0';
                       if(ll<jj){
                         if(itimes==1){
                           if(mle>=1)
                             printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                           fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                           fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                         }else{
                           if(mle>=1)
                             printf(" %.5e",matcov[jj][ll]); 
                           fprintf(ficlog," %.5e",matcov[jj][ll]); 
                           fprintf(ficres," %.5e",matcov[jj][ll]); 
                         }
                       }else{
                         if(itimes==1){
                           if(mle>=1)
                             printf(" Var(%s%1d%1d)",ca,i,j);
                           fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                           fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                         }else{
                           if(mle>=1)
                             printf(" %.5e",matcov[jj][ll]); 
                           fprintf(ficlog," %.5e",matcov[jj][ll]); 
                           fprintf(ficres," %.5e",matcov[jj][ll]); 
                         }
                       }
                     }
                   } /* end lk */
                 } /* end lj */
               } /* end li */
               if(mle>=1)
                 printf("\n");
               fprintf(ficlog,"\n");
               fprintf(ficres,"\n");
               numlinepar++;
             } /* end k*/
           } /*end j */
         } /* end i */
       } /* end itimes */
       
       fflush(ficlog);
       fflush(ficres);
       
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         fputs(line,stdout);
         fputs(line,ficparo);
       }
       ungetc(c,ficpar);
       
       estepm=0;
       fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm);
       if (estepm==0 || estepm < stepm) estepm=stepm;
       if (fage <= 2) {
         bage = ageminpar;
         fage = agemaxpar;
       }
       
       fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
       fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d\n",ageminpar,agemaxpar,bage,fage, estepm);
       fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d\n",ageminpar,agemaxpar,bage,fage, estepm);
       
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         fputs(line,stdout);
         fputs(line,ficparo);
       }
       ungetc(c,ficpar);
       
       fscanf(ficpar,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav);
       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
       
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         fputs(line,stdout);
         fputs(line,ficparo);
       }
       ungetc(c,ficpar);
       
       
       dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
       dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
       
       fscanf(ficpar,"pop_based=%d\n",&popbased);
       fprintf(ficparo,"pop_based=%d\n",popbased);   
       fprintf(ficres,"pop_based=%d\n",popbased);   
       
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         fputs(line,stdout);
         fputs(line,ficparo);
       }
       ungetc(c,ficpar);
       
       fscanf(ficpar,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj);
       fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
       printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
       fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
       fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
       /* day and month of proj2 are not used but only year anproj2.*/
       
       
       
        /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
       /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
       
       replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
       printinggnuplot(fileres, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
       
       printinghtml(fileres,title,datafile, firstpass, lastpass, stepm, weightopt,\
                    model,imx,jmin,jmax,jmean,rfileres,popforecast,estepm,\
                    jprev1,mprev1,anprev1,jprev2,mprev2,anprev2);
         
      /*------------ free_vector  -------------*/
      /*  chdir(path); */
    
       free_ivector(wav,1,imx);
       free_imatrix(dh,1,lastpass-firstpass+1,1,imx);
       free_imatrix(bh,1,lastpass-firstpass+1,1,imx);
       free_imatrix(mw,1,lastpass-firstpass+1,1,imx);   
       free_lvector(num,1,n);
       free_vector(agedc,1,n);
       /*free_matrix(covar,0,NCOVMAX,1,n);*/
       /*free_matrix(covar,1,NCOVMAX,1,n);*/
       fclose(ficparo);
       fclose(ficres);
   
   
       /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
   #include "prevlim.h"  /* Use ficrespl, ficlog */
       fclose(ficrespl);
   
   #ifdef FREEEXIT2
   #include "freeexit2.h"
   #endif
   
       /*------------- h Pij x at various ages ------------*/
   #include "hpijx.h"
       fclose(ficrespij);
   
     /*-------------- Variance of one-step probabilities---*/
       k=1;
       varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
   
   
       probs= ma3x(1,AGESUP,1,NCOVMAX, 1,NCOVMAX);
       for(i=1;i<=AGESUP;i++)
         for(j=1;j<=NCOVMAX;j++)
           for(k=1;k<=NCOVMAX;k++)
             probs[i][j][k]=0.;
   
       /*---------- Forecasting ------------------*/
       /*if((stepm == 1) && (strcmp(model,".")==0)){*/
       if(prevfcast==1){
         /*    if(stepm ==1){*/
         prevforecast(fileres, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
         /* (popforecast==1) populforecast(fileres, anpyram,mpyram,jpyram, agemin,agemax, dateprev1, dateprev2,mobilav, agedeb, fage, popforecast, popfile, anpyram1,p, i1);*/
         /*      }  */
         /*      else{ */
         /*        erreur=108; */
         /*        printf("Warning %d!! You can only forecast the prevalences if the optimization\n  has been performed with stepm = 1 (month) instead of %d or model=. instead of '%s'\n", erreur, stepm, model); */
         /*        fprintf(ficlog,"Warning %d!! You can only forecast the prevalences if the optimization\n  has been performed with stepm = 1 (month) instead of %d or model=. instead of '%s'\n", erreur, stepm, model); */
         /*      } */
       }
     
   
       /* Computes prevalence between agemin (i.e minimal age computed) and no more ageminpar */
   
       prevalence(probs, agemin, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
       /*  printf("ageminpar=%f, agemax=%f, s[lastpass][imx]=%d, agev[lastpass][imx]=%f, nlstate=%d, imx=%d,  mint[lastpass][imx]=%f, anint[lastpass][imx]=%f,dateprev1=%f, dateprev2=%f, firstpass=%d, lastpass=%d\n",\
           ageminpar, agemax, s[lastpass][imx], agev[lastpass][imx], nlstate, imx, mint[lastpass][imx],anint[lastpass][imx], dateprev1, dateprev2, firstpass, lastpass);
       */
   
       if (mobilav!=0) {
         mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
         if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){
           fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
           printf(" Error in movingaverage mobilav=%d\n",mobilav);
         }
       }
   
   
       /*---------- Health expectancies, no variances ------------*/
   
       strcpy(filerese,"e");
       strcat(filerese,fileres);
       if((ficreseij=fopen(filerese,"w"))==NULL) {
         printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
         fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
       }
       printf("Computing Health Expectancies: result on file '%s' \n", filerese);
       fprintf(ficlog,"Computing Health Expectancies: result on file '%s' \n", filerese);
       /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
         for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
             
       for (k=1; k <= (int) pow(2,cptcoveff); k++){
           fprintf(ficreseij,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) {
             fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
           }
           fprintf(ficreseij,"******\n");
   
           eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
           oldm=oldms;savm=savms;
           evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart);  
         
           free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
         /*}*/
       }
       fclose(ficreseij);
   
   
       /*---------- Health expectancies and variances ------------*/
   
   
       strcpy(filerest,"t");
       strcat(filerest,fileres);
       if((ficrest=fopen(filerest,"w"))==NULL) {
         printf("Problem with total LE resultfile: %s\n", filerest);goto end;
         fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
       }
       printf("Computing Total Life expectancies with their standard errors: file '%s' \n", filerest); 
       fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' \n", filerest); 
   
   
       strcpy(fileresstde,"stde");
       strcat(fileresstde,fileres);
       if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
         printf("Problem with Health Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
         fprintf(ficlog,"Problem with Health Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
       }
       printf("Computing Health Expectancies and standard errors: result on file '%s' \n", fileresstde);
       fprintf(ficlog,"Computing Health Expectancies and standard errors: result on file '%s' \n", fileresstde);
   
       strcpy(filerescve,"cve");
       strcat(filerescve,fileres);
       if((ficrescveij=fopen(filerescve,"w"))==NULL) {
         printf("Problem with Covar. Health Exp. resultfile: %s\n", filerescve); exit(0);
         fprintf(ficlog,"Problem with Covar. Health Exp. resultfile: %s\n", filerescve); exit(0);
       }
       printf("Computing Covar. of Health Expectancies: result on file '%s' \n", filerescve);
       fprintf(ficlog,"Computing Covar. of Health Expectancies: result on file '%s' \n", filerescve);
   
       strcpy(fileresv,"v");
       strcat(fileresv,fileres);
       if((ficresvij=fopen(fileresv,"w"))==NULL) {
         printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
         fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
       }
       printf("Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);
       fprintf(ficlog,"Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);
   
       /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
         for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
             
       for (k=1; k <= (int) pow(2,cptcoveff); k++){
           fprintf(ficrest,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) 
             fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
           fprintf(ficrest,"******\n");
   
           fprintf(ficresstdeij,"\n#****** ");
           fprintf(ficrescveij,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) {
             fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
             fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
           }
           fprintf(ficresstdeij,"******\n");
           fprintf(ficrescveij,"******\n");
   
           fprintf(ficresvij,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) 
             fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
           fprintf(ficresvij,"******\n");
   
           eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
           oldm=oldms;savm=savms;
           cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart);  
           /*
            */
           /* goto endfree; */
    
           vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
           pstamp(ficrest);
   
   
           for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
             oldm=oldms;savm=savms; /* Segmentation fault */
             varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart);
             fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
             if(vpopbased==1)
               fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
             else
               fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
             fprintf(ficrest,"# Age e.. (std) ");
             for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
             fprintf(ficrest,"\n");
   
             epj=vector(1,nlstate+1);
             for(age=bage; age <=fage ;age++){
               prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);
               if (vpopbased==1) {
                 if(mobilav ==0){
                   for(i=1; i<=nlstate;i++)
                     prlim[i][i]=probs[(int)age][i][k];
                 }else{ /* mobilav */ 
                   for(i=1; i<=nlstate;i++)
                     prlim[i][i]=mobaverage[(int)age][i][k];
                 }
               }
           
               fprintf(ficrest," %4.0f",age);
               for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                 for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   /*  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                 }
                 epj[nlstate+1] +=epj[j];
               }
   
               for(i=1, vepp=0.;i <=nlstate;i++)
                 for(j=1;j <=nlstate;j++)
                   vepp += vareij[i][j][(int)age];
               fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
               for(j=1;j <=nlstate;j++){
                 fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
               }
               fprintf(ficrest,"\n");
             }
           }
           free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
           free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
           free_vector(epj,1,nlstate+1);
         /*}*/
       }
       free_vector(weight,1,n);
       free_imatrix(Tvard,1,NCOVMAX,1,2);
       free_imatrix(s,1,maxwav+1,1,n);
       free_matrix(anint,1,maxwav,1,n); 
       free_matrix(mint,1,maxwav,1,n);
       free_ivector(cod,1,n);
       free_ivector(tab,1,NCOVMAX);
       fclose(ficresstdeij);
       fclose(ficrescveij);
       fclose(ficresvij);
       fclose(ficrest);
       fclose(ficpar);
     
       /*------- Variance of period (stable) prevalence------*/   
   
       strcpy(fileresvpl,"vpl");
       strcat(fileresvpl,fileres);
       if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
         printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
         exit(0);
       }
       printf("Computing Variance-covariance of period (stable) prevalence: file '%s' \n", fileresvpl);
   
       /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
         for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
             
       for (k=1; k <= (int) pow(2,cptcoveff); k++){
           fprintf(ficresvpl,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) 
             fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
           fprintf(ficresvpl,"******\n");
         
           varpl=matrix(1,nlstate,(int) bage, (int) fage);
           oldm=oldms;savm=savms;
           varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k,strstart);
           free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
         /*}*/
       }
   
       fclose(ficresvpl);
   
       /*---------- End : free ----------------*/
       if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       free_ma3x(probs,1,AGESUP,1,NCOVMAX, 1,NCOVMAX);
     }  /* mle==-3 arrives here for freeing */
    endfree:
       free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
       free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
       free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
       free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
       free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
       free_matrix(covar,0,NCOVMAX,1,n);
       free_matrix(matcov,1,npar,1,npar);
       /*free_vector(delti,1,npar);*/
       free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
       free_matrix(agev,1,maxwav,1,imx);
       free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
   
       free_ivector(ncodemax,1,NCOVMAX);
       free_ivector(Tvar,1,NCOVMAX);
       free_ivector(Tprod,1,NCOVMAX);
       free_ivector(Tvaraff,1,NCOVMAX);
       free_ivector(Tage,1,NCOVMAX);
   
       free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
       free_imatrix(codtab,1,100,1,10);
     fflush(fichtm);
     fflush(ficgp);
     
   
     if((nberr >0) || (nbwarn>0)){
       printf("End of Imach with %d errors and/or %d warnings\n",nberr,nbwarn);
       fprintf(ficlog,"End of Imach with %d errors and/or warnings %d\n",nberr,nbwarn);
     }else{
       printf("End of Imach\n");
       fprintf(ficlog,"End of Imach\n");
     }
     printf("See log file on %s\n",filelog);
     /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
     /*(void) gettimeofday(&end_time,&tzp);*/
     rend_time = time(NULL);  
     end_time = *localtime(&rend_time);
     /* tml = *localtime(&end_time.tm_sec); */
     strcpy(strtend,asctime(&end_time));
     printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
     fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
     printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
   
     printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
     fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
     fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
     /*  printf("Total time was %d uSec.\n", total_usecs);*/
   /*   if(fileappend(fichtm,optionfilehtm)){ */
     fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
     fclose(fichtm);
     fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
     fclose(fichtmcov);
     fclose(ficgp);
     fclose(ficlog);
     /*------ End -----------*/
   
   
      printf("Before Current directory %s!\n",pathcd);
      if(chdir(pathcd) != 0)
       printf("Can't move to directory %s!\n",path);
     if(getcwd(pathcd,MAXLINE) > 0)
       printf("Current directory %s!\n",pathcd);
     /*strcat(plotcmd,CHARSEPARATOR);*/
     sprintf(plotcmd,"gnuplot");
   #ifdef _WIN32
     sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
   #endif
     if(!stat(plotcmd,&info)){
       printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
       if(!stat(getenv("GNUPLOTBIN"),&info)){
         printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
       }else
         strcpy(pplotcmd,plotcmd);
   #ifdef __unix
       strcpy(plotcmd,GNUPLOTPROGRAM);
       if(!stat(plotcmd,&info)){
         printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
       }else
         strcpy(pplotcmd,plotcmd);
   #endif
     }else
       strcpy(pplotcmd,plotcmd);
     
     sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
     printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
   
     if((outcmd=system(plotcmd)) != 0){
       printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
       printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
       sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
       if((outcmd=system(plotcmd)) != 0)
         printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
     }
     printf(" Successful, please wait...");
     while (z[0] != 'q') {
       /* chdir(path); */
       printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
       scanf("%s",z);
   /*     if (z[0] == 'c') system("./imach"); */
       if (z[0] == 'e') {
   #ifdef __APPLE__
         sprintf(pplotcmd, "open %s", optionfilehtm);
   #elif __linux
         sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
   #else
         sprintf(pplotcmd, "%s", optionfilehtm);
   #endif
         printf("Starting browser with: %s",pplotcmd);fflush(stdout);
         system(pplotcmd);
       }
       else if (z[0] == 'g') system(plotcmd);
       else if (z[0] == 'q') exit(0);
     }
     end:
     while (z[0] != 'q') {
       printf("\nType  q for exiting: ");
       scanf("%s",z);
     }
   }

Removed from v.1.8  
changed lines
  Added in v.1.160


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