Diff for /imach/src/imach.c between versions 1.51 and 1.201

version 1.51, 2002/07/19 12:22:25 version 1.201, 2015/09/15 17:34:58
Line 1 Line 1
 /* $Id$  /* $Id$
    Interpolated Markov Chain    $State$
     $Log$
   Short summary of the programme:    Revision 1.201  2015/09/15 17:34:58  brouard
      Summary: 0.98r0
   This program computes Healthy Life Expectancies from  
   cross-longitudinal data. Cross-longitudinal data consist in: -1- a    - Some new graphs like suvival functions
   first survey ("cross") where individuals from different ages are    - Some bugs fixed like model=1+age+V2.
   interviewed on their health status or degree of disability (in the  
   case of a health survey which is our main interest) -2- at least a    Revision 1.200  2015/09/09 16:53:55  brouard
   second wave of interviews ("longitudinal") which measure each change    Summary: Big bug thanks to Flavia
   (if any) in individual health status.  Health expectancies are  
   computed from the time spent in each health state according to a    Even model=1+age+V2. did not work anymore
   model. More health states you consider, more time is necessary to reach the  
   Maximum Likelihood of the parameters involved in the model.  The    Revision 1.199  2015/09/07 14:09:23  brouard
   simplest model is the multinomial logistic model where pij is the    Summary: 0.98q6 changing default small png format for graph to vectorized svg.
   probability to be observed in state j at the second wave  
   conditional to be observed in state i at the first wave. Therefore    Revision 1.198  2015/09/03 07:14:39  brouard
   the model is: log(pij/pii)= aij + bij*age+ cij*sex + etc , where    Summary: 0.98q5 Flavia
   'age' is age and 'sex' is a covariate. If you want to have a more  
   complex model than "constant and age", you should modify the program    Revision 1.197  2015/09/01 18:24:39  brouard
   where the markup *Covariates have to be included here again* invites    *** empty log message ***
   you to do it.  More covariates you add, slower the  
   convergence.    Revision 1.196  2015/08/18 23:17:52  brouard
     Summary: 0.98q5
   The advantage of this computer programme, compared to a simple  
   multinomial logistic model, is clear when the delay between waves is not    Revision 1.195  2015/08/18 16:28:39  brouard
   identical for each individual. Also, if a individual missed an    Summary: Adding a hack for testing purpose
   intermediate interview, the information is lost, but taken into  
   account using an interpolation or extrapolation.      After reading the title, ftol and model lines, if the comment line has
     a q, starting with #q, the answer at the end of the run is quit. It
   hPijx is the probability to be observed in state i at age x+h    permits to run test files in batch with ctest. The former workaround was
   conditional to the observed state i at age x. The delay 'h' can be    $ echo q | imach foo.imach
   split into an exact number (nh*stepm) of unobserved intermediate  
   states. This elementary transition (by month or quarter trimester,    Revision 1.194  2015/08/18 13:32:00  brouard
   semester or year) is model as a multinomial logistic.  The hPx    Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
   matrix is simply the matrix product of nh*stepm elementary matrices  
   and the contribution of each individual to the likelihood is simply    Revision 1.193  2015/08/04 07:17:42  brouard
   hPijx.    Summary: 0.98q4
   
   Also this programme outputs the covariance matrix of the parameters but also    Revision 1.192  2015/07/16 16:49:02  brouard
   of the life expectancies. It also computes the prevalence limits.    Summary: Fixing some outputs
    
   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).    Revision 1.191  2015/07/14 10:00:33  brouard
            Institut national d'études démographiques, Paris.    Summary: Some fixes
   This software have been partly granted by Euro-REVES, a concerted action  
   from the European Union.    Revision 1.190  2015/05/05 08:51:13  brouard
   It is copyrighted identically to a GNU software product, ie programme and    Summary: Adding digits in output parameters (7 digits instead of 6)
   software can be distributed freely for non commercial use. Latest version  
   can be accessed at http://euroreves.ined.fr/imach .    Fix 1+age+.
   **********************************************************************/  
      Revision 1.189  2015/04/30 14:45:16  brouard
 #include <math.h>    Summary: 0.98q2
 #include <stdio.h>  
 #include <stdlib.h>    Revision 1.188  2015/04/30 08:27:53  brouard
 #include <unistd.h>    *** empty log message ***
   
 #define MAXLINE 256    Revision 1.187  2015/04/29 09:11:15  brouard
 #define GNUPLOTPROGRAM "gnuplot"    *** empty log message ***
 /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/  
 #define FILENAMELENGTH 80    Revision 1.186  2015/04/23 12:01:52  brouard
 /*#define DEBUG*/    Summary: V1*age is working now, version 0.98q1
 #define windows  
 #define GLOCK_ERROR_NOPATH              -1      /* empty path */    Some codes had been disabled in order to simplify and Vn*age was
 #define GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */    working in the optimization phase, ie, giving correct MLE parameters,
     but, as usual, outputs were not correct and program core dumped.
 #define MAXPARM 30 /* Maximum number of parameters for the optimization */  
 #define NPARMAX 64 /* (nlstate+ndeath-1)*nlstate*ncovmodel */    Revision 1.185  2015/03/11 13:26:42  brouard
     Summary: Inclusion of compile and links command line for Intel Compiler
 #define NINTERVMAX 8  
 #define NLSTATEMAX 8 /* Maximum number of live states (for func) */    Revision 1.184  2015/03/11 11:52:39  brouard
 #define NDEATHMAX 8 /* Maximum number of dead states (for func) */    Summary: Back from Windows 8. Intel Compiler
 #define NCOVMAX 8 /* Maximum number of covariates */  
 #define MAXN 20000    Revision 1.183  2015/03/10 20:34:32  brouard
 #define YEARM 12. /* Number of months per year */    Summary: 0.98q0, trying with directest, mnbrak fixed
 #define AGESUP 130  
 #define AGEBASE 40    We use directest instead of original Powell test; probably no
 #ifdef windows    incidence on the results, but better justifications;
 #define DIRSEPARATOR '\\'    We fixed Numerical Recipes mnbrak routine which was wrong and gave
 #define ODIRSEPARATOR '/'    wrong results.
 #else  
 #define DIRSEPARATOR '/'    Revision 1.182  2015/02/12 08:19:57  brouard
 #define ODIRSEPARATOR '\\'    Summary: Trying to keep directest which seems simpler and more general
 #endif    Author: Nicolas Brouard
   
 char version[80]="Imach version 0.8i, June 2002, INED-EUROREVES ";    Revision 1.181  2015/02/11 23:22:24  brouard
 int erreur; /* Error number */    Summary: Comments on Powell added
 int nvar;  
 int cptcovn=0, cptcovage=0, cptcoveff=0,cptcov;    Author:
 int npar=NPARMAX;  
 int nlstate=2; /* Number of live states */    Revision 1.180  2015/02/11 17:33:45  brouard
 int ndeath=1; /* Number of dead states */    Summary: Finishing move from main to function (hpijx and prevalence_limit)
 int ncovmodel, ncovcol;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */  
 int popbased=0;    Revision 1.179  2015/01/04 09:57:06  brouard
     Summary: back to OS/X
 int *wav; /* Number of waves for this individuual 0 is possible */  
 int maxwav; /* Maxim number of waves */    Revision 1.178  2015/01/04 09:35:48  brouard
 int jmin, jmax; /* min, max spacing between 2 waves */    *** empty log message ***
 int mle, weightopt;  
 int **mw; /* mw[mi][i] is number of the mi wave for this individual */    Revision 1.177  2015/01/03 18:40:56  brouard
 int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */    Summary: Still testing ilc32 on OSX
 double jmean; /* Mean space between 2 waves */  
 double **oldm, **newm, **savm; /* Working pointers to matrices */    Revision 1.176  2015/01/03 16:45:04  brouard
 double **oldms, **newms, **savms; /* Fixed working pointers to matrices */    *** empty log message ***
 FILE *fic,*ficpar, *ficparo,*ficres,  *ficrespl, *ficrespij, *ficrest,*ficresf,*ficrespop;  
 FILE *ficlog;    Revision 1.175  2015/01/03 16:33:42  brouard
 FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;    *** empty log message ***
 FILE *ficresprobmorprev;  
 FILE *fichtm; /* Html File */    Revision 1.174  2015/01/03 16:15:49  brouard
 FILE *ficreseij;    Summary: Still in cross-compilation
 char filerese[FILENAMELENGTH];  
 FILE  *ficresvij;    Revision 1.173  2015/01/03 12:06:26  brouard
 char fileresv[FILENAMELENGTH];    Summary: trying to detect cross-compilation
 FILE  *ficresvpl;  
 char fileresvpl[FILENAMELENGTH];    Revision 1.172  2014/12/27 12:07:47  brouard
 char title[MAXLINE];    Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
 char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH];  
 char optionfilext[10], optionfilefiname[FILENAMELENGTH], plotcmd[FILENAMELENGTH];    Revision 1.171  2014/12/23 13:26:59  brouard
     Summary: Back from Visual C
 char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];  
 char filelog[FILENAMELENGTH]; /* Log file */    Still problem with utsname.h on Windows
 char filerest[FILENAMELENGTH];  
 char fileregp[FILENAMELENGTH];    Revision 1.170  2014/12/23 11:17:12  brouard
 char popfile[FILENAMELENGTH];    Summary: Cleaning some \%% back to %%
   
 char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH];    The escape was mandatory for a specific compiler (which one?), but too many warnings.
   
 #define NR_END 1    Revision 1.169  2014/12/22 23:08:31  brouard
 #define FREE_ARG char*    Summary: 0.98p
 #define FTOL 1.0e-10  
     Outputs some informations on compiler used, OS etc. Testing on different platforms.
 #define NRANSI  
 #define ITMAX 200    Revision 1.168  2014/12/22 15:17:42  brouard
     Summary: update
 #define TOL 2.0e-4  
     Revision 1.167  2014/12/22 13:50:56  brouard
 #define CGOLD 0.3819660    Summary: Testing uname and compiler version and if compiled 32 or 64
 #define ZEPS 1.0e-10  
 #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d);    Testing on Linux 64
   
 #define GOLD 1.618034    Revision 1.166  2014/12/22 11:40:47  brouard
 #define GLIMIT 100.0    *** empty log message ***
 #define TINY 1.0e-20  
     Revision 1.165  2014/12/16 11:20:36  brouard
 static double maxarg1,maxarg2;    Summary: After compiling on Visual C
 #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))  
 #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))    * imach.c (Module): Merging 1.61 to 1.162
    
 #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))    Revision 1.164  2014/12/16 10:52:11  brouard
 #define rint(a) floor(a+0.5)    Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
   
 static double sqrarg;    * imach.c (Module): Merging 1.61 to 1.162
 #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)  
 #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;}    Revision 1.163  2014/12/16 10:30:11  brouard
     * imach.c (Module): Merging 1.61 to 1.162
 int imx;  
 int stepm;    Revision 1.162  2014/09/25 11:43:39  brouard
 /* Stepm, step in month: minimum step interpolation*/    Summary: temporary backup 0.99!
   
 int estepm;    Revision 1.1  2014/09/16 11:06:58  brouard
 /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/    Summary: With some code (wrong) for nlopt
   
 int m,nb;    Author:
 int *num, firstpass=0, lastpass=4,*cod, *ncodemax, *Tage;  
 double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;    Revision 1.161  2014/09/15 20:41:41  brouard
 double **pmmij, ***probs, ***mobaverage;    Summary: Problem with macro SQR on Intel compiler
 double dateintmean=0;  
     Revision 1.160  2014/09/02 09:24:05  brouard
 double *weight;    *** empty log message ***
 int **s; /* Status */  
 double *agedc, **covar, idx;    Revision 1.159  2014/09/01 10:34:10  brouard
 int **nbcode, *Tcode, *Tvar, **codtab, **Tvard, *Tprod, cptcovprod, *Tvaraff;    Summary: WIN32
     Author: Brouard
 double ftol=FTOL; /* Tolerance for computing Max Likelihood */  
 double ftolhess; /* Tolerance for computing hessian */    Revision 1.158  2014/08/27 17:11:51  brouard
     *** empty log message ***
 /**************** split *************************/  
 static  int split( char *path, char *dirc, char *name, char *ext, char *finame )    Revision 1.157  2014/08/27 16:26:55  brouard
 {    Summary: Preparing windows Visual studio version
    char *s;                             /* pointer */    Author: Brouard
    int  l1, l2;                         /* length counters */  
     In order to compile on Visual studio, time.h is now correct and time_t
    l1 = strlen( path );                 /* length of path */    and tm struct should be used. difftime should be used but sometimes I
    if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );    just make the differences in raw time format (time(&now).
    s= strrchr( path, DIRSEPARATOR );            /* find last / */    Trying to suppress #ifdef LINUX
    if ( s == NULL ) {                   /* no directory, so use current */    Add xdg-open for __linux in order to open default browser.
      /*if(strrchr(path, ODIRSEPARATOR )==NULL)  
        printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/    Revision 1.156  2014/08/25 20:10:10  brouard
 #if     defined(__bsd__)                /* get current working directory */    *** empty log message ***
       extern char       *getwd( );  
     Revision 1.155  2014/08/25 18:32:34  brouard
       if ( getwd( dirc ) == NULL ) {    Summary: New compile, minor changes
 #else    Author: Brouard
       extern char       *getcwd( );  
     Revision 1.154  2014/06/20 17:32:08  brouard
       if ( getcwd( dirc, FILENAME_MAX ) == NULL ) {    Summary: Outputs now all graphs of convergence to period prevalence
 #endif  
          return( GLOCK_ERROR_GETCWD );    Revision 1.153  2014/06/20 16:45:46  brouard
       }    Summary: If 3 live state, convergence to period prevalence on same graph
       strcpy( name, path );             /* we've got it */    Author: Brouard
    } else {                             /* strip direcotry from path */  
       s++;                              /* after this, the filename */    Revision 1.152  2014/06/18 17:54:09  brouard
       l2 = strlen( s );                 /* length of filename */    Summary: open browser, use gnuplot on same dir than imach if not found in the path
       if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );  
       strcpy( name, s );                /* save file name */    Revision 1.151  2014/06/18 16:43:30  brouard
       strncpy( dirc, path, l1 - l2 );   /* now the directory */    *** empty log message ***
       dirc[l1-l2] = 0;                  /* add zero */  
    }    Revision 1.150  2014/06/18 16:42:35  brouard
    l1 = strlen( dirc );                 /* length of directory */    Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
 #ifdef windows    Author: brouard
    if ( dirc[l1-1] != '\\' ) { dirc[l1] = '\\'; dirc[l1+1] = 0; }  
 #else    Revision 1.149  2014/06/18 15:51:14  brouard
    if ( dirc[l1-1] != '/' ) { dirc[l1] = '/'; dirc[l1+1] = 0; }    Summary: Some fixes in parameter files errors
 #endif    Author: Nicolas Brouard
    s = strrchr( name, '.' );            /* find last / */  
    s++;    Revision 1.148  2014/06/17 17:38:48  brouard
    strcpy(ext,s);                       /* save extension */    Summary: Nothing new
    l1= strlen( name);    Author: Brouard
    l2= strlen( s)+1;  
    strncpy( finame, name, l1-l2);    Just a new packaging for OS/X version 0.98nS
    finame[l1-l2]= 0;  
    return( 0 );                         /* we're done */    Revision 1.147  2014/06/16 10:33:11  brouard
 }    *** empty log message ***
   
     Revision 1.146  2014/06/16 10:20:28  brouard
 /******************************************/    Summary: Merge
     Author: Brouard
 void replace(char *s, char*t)  
 {    Merge, before building revised version.
   int i;  
   int lg=20;    Revision 1.145  2014/06/10 21:23:15  brouard
   i=0;    Summary: Debugging with valgrind
   lg=strlen(t);    Author: Nicolas Brouard
   for(i=0; i<= lg; i++) {  
     (s[i] = t[i]);    Lot of changes in order to output the results with some covariates
     if (t[i]== '\\') s[i]='/';    After the Edimburgh REVES conference 2014, it seems mandatory to
   }    improve the code.
 }    No more memory valgrind error but a lot has to be done in order to
     continue the work of splitting the code into subroutines.
 int nbocc(char *s, char occ)    Also, decodemodel has been improved. Tricode is still not
 {    optimal. nbcode should be improved. Documentation has been added in
   int i,j=0;    the source code.
   int lg=20;  
   i=0;    Revision 1.143  2014/01/26 09:45:38  brouard
   lg=strlen(s);    Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
   for(i=0; i<= lg; i++) {  
   if  (s[i] == occ ) j++;    * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
   }    (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
   return j;  
 }    Revision 1.142  2014/01/26 03:57:36  brouard
     Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
 void cutv(char *u,char *v, char*t, char occ)  
 {    * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
   /* cuts string t into u and v where u is ended by char occ excluding it  
      and v is after occ excluding it too : ex cutv(u,v,"abcdef2ghi2j",2)    Revision 1.141  2014/01/26 02:42:01  brouard
      gives u="abcedf" and v="ghi2j" */    * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
   int i,lg,j,p=0;  
   i=0;    Revision 1.140  2011/09/02 10:37:54  brouard
   for(j=0; j<=strlen(t)-1; j++) {    Summary: times.h is ok with mingw32 now.
     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1;  
   }    Revision 1.139  2010/06/14 07:50:17  brouard
     After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
   lg=strlen(t);    I remember having already fixed agemin agemax which are pointers now but not cvs saved.
   for(j=0; j<p; j++) {  
     (u[j] = t[j]);    Revision 1.138  2010/04/30 18:19:40  brouard
   }    *** empty log message ***
      u[p]='\0';  
     Revision 1.137  2010/04/29 18:11:38  brouard
    for(j=0; j<= lg; j++) {    (Module): Checking covariates for more complex models
     if (j>=(p+1))(v[j-p-1] = t[j]);    than V1+V2. A lot of change to be done. Unstable.
   }  
 }    Revision 1.136  2010/04/26 20:30:53  brouard
     (Module): merging some libgsl code. Fixing computation
 /********************** nrerror ********************/    of likelione (using inter/intrapolation if mle = 0) in order to
     get same likelihood as if mle=1.
 void nrerror(char error_text[])    Some cleaning of code and comments added.
 {  
   fprintf(stderr,"ERREUR ...\n");    Revision 1.135  2009/10/29 15:33:14  brouard
   fprintf(stderr,"%s\n",error_text);    (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
   exit(1);  
 }    Revision 1.134  2009/10/29 13:18:53  brouard
 /*********************** vector *******************/    (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
 double *vector(int nl, int nh)  
 {    Revision 1.133  2009/07/06 10:21:25  brouard
   double *v;    just nforces
   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));  
   if (!v) nrerror("allocation failure in vector");    Revision 1.132  2009/07/06 08:22:05  brouard
   return v-nl+NR_END;    Many tings
 }  
     Revision 1.131  2009/06/20 16:22:47  brouard
 /************************ free vector ******************/    Some dimensions resccaled
 void free_vector(double*v, int nl, int nh)  
 {    Revision 1.130  2009/05/26 06:44:34  brouard
   free((FREE_ARG)(v+nl-NR_END));    (Module): Max Covariate is now set to 20 instead of 8. A
 }    lot of cleaning with variables initialized to 0. Trying to make
     V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
 /************************ivector *******************************/  
 int *ivector(long nl,long nh)    Revision 1.129  2007/08/31 13:49:27  lievre
 {    Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
   int *v;  
   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));    Revision 1.128  2006/06/30 13:02:05  brouard
   if (!v) nrerror("allocation failure in ivector");    (Module): Clarifications on computing e.j
   return v-nl+NR_END;  
 }    Revision 1.127  2006/04/28 18:11:50  brouard
     (Module): Yes the sum of survivors was wrong since
 /******************free ivector **************************/    imach-114 because nhstepm was no more computed in the age
 void free_ivector(int *v, long nl, long nh)    loop. Now we define nhstepma in the age loop.
 {    (Module): In order to speed up (in case of numerous covariates) we
   free((FREE_ARG)(v+nl-NR_END));    compute health expectancies (without variances) in a first step
 }    and then all the health expectancies with variances or standard
     deviation (needs data from the Hessian matrices) which slows the
 /******************* imatrix *******************************/    computation.
 int **imatrix(long nrl, long nrh, long ncl, long nch)    In the future we should be able to stop the program is only health
      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */    expectancies and graph are needed without standard deviations.
 {  
   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1;    Revision 1.126  2006/04/28 17:23:28  brouard
   int **m;    (Module): Yes the sum of survivors was wrong since
      imach-114 because nhstepm was no more computed in the age
   /* allocate pointers to rows */    loop. Now we define nhstepma in the age loop.
   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*)));    Version 0.98h
   if (!m) nrerror("allocation failure 1 in matrix()");  
   m += NR_END;    Revision 1.125  2006/04/04 15:20:31  lievre
   m -= nrl;    Errors in calculation of health expectancies. Age was not initialized.
      Forecasting file added.
    
   /* allocate rows and set pointers to them */    Revision 1.124  2006/03/22 17:13:53  lievre
   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int)));    Parameters are printed with %lf instead of %f (more numbers after the comma).
   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");    The log-likelihood is printed in the log file
   m[nrl] += NR_END;  
   m[nrl] -= ncl;    Revision 1.123  2006/03/20 10:52:43  brouard
      * imach.c (Module): <title> changed, corresponds to .htm file
   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol;    name. <head> headers where missing.
    
   /* return pointer to array of pointers to rows */    * imach.c (Module): Weights can have a decimal point as for
   return m;    English (a comma might work with a correct LC_NUMERIC environment,
 }    otherwise the weight is truncated).
     Modification of warning when the covariates values are not 0 or
 /****************** free_imatrix *************************/    1.
 void free_imatrix(m,nrl,nrh,ncl,nch)    Version 0.98g
       int **m;  
       long nch,ncl,nrh,nrl;    Revision 1.122  2006/03/20 09:45:41  brouard
      /* free an int matrix allocated by imatrix() */    (Module): Weights can have a decimal point as for
 {    English (a comma might work with a correct LC_NUMERIC environment,
   free((FREE_ARG) (m[nrl]+ncl-NR_END));    otherwise the weight is truncated).
   free((FREE_ARG) (m+nrl-NR_END));    Modification of warning when the covariates values are not 0 or
 }    1.
     Version 0.98g
 /******************* matrix *******************************/  
 double **matrix(long nrl, long nrh, long ncl, long nch)    Revision 1.121  2006/03/16 17:45:01  lievre
 {    * imach.c (Module): Comments concerning covariates added
   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;  
   double **m;    * imach.c (Module): refinements in the computation of lli if
     status=-2 in order to have more reliable computation if stepm is
   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));    not 1 month. Version 0.98f
   if (!m) nrerror("allocation failure 1 in matrix()");  
   m += NR_END;    Revision 1.120  2006/03/16 15:10:38  lievre
   m -= nrl;    (Module): refinements in the computation of lli if
     status=-2 in order to have more reliable computation if stepm is
   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));    not 1 month. Version 0.98f
   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");  
   m[nrl] += NR_END;    Revision 1.119  2006/03/15 17:42:26  brouard
   m[nrl] -= ncl;    (Module): Bug if status = -2, the loglikelihood was
     computed as likelihood omitting the logarithm. Version O.98e
   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;  
   return m;    Revision 1.118  2006/03/14 18:20:07  brouard
 }    (Module): varevsij Comments added explaining the second
     table of variances if popbased=1 .
 /*************************free matrix ************************/    (Module): Covariances of eij, ekl added, graphs fixed, new html link.
 void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)    (Module): Function pstamp added
 {    (Module): Version 0.98d
   free((FREE_ARG)(m[nrl]+ncl-NR_END));  
   free((FREE_ARG)(m+nrl-NR_END));    Revision 1.117  2006/03/14 17:16:22  brouard
 }    (Module): varevsij Comments added explaining the second
     table of variances if popbased=1 .
 /******************* ma3x *******************************/    (Module): Covariances of eij, ekl added, graphs fixed, new html link.
 double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)    (Module): Function pstamp added
 {    (Module): Version 0.98d
   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;  
   double ***m;    Revision 1.116  2006/03/06 10:29:27  brouard
     (Module): Variance-covariance wrong links and
   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));    varian-covariance of ej. is needed (Saito).
   if (!m) nrerror("allocation failure 1 in matrix()");  
   m += NR_END;    Revision 1.115  2006/02/27 12:17:45  brouard
   m -= nrl;    (Module): One freematrix added in mlikeli! 0.98c
   
   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));    Revision 1.114  2006/02/26 12:57:58  brouard
   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");    (Module): Some improvements in processing parameter
   m[nrl] += NR_END;    filename with strsep.
   m[nrl] -= ncl;  
     Revision 1.113  2006/02/24 14:20:24  brouard
   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;    (Module): Memory leaks checks with valgrind and:
     datafile was not closed, some imatrix were not freed and on matrix
   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));    allocation too.
   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");  
   m[nrl][ncl] += NR_END;    Revision 1.112  2006/01/30 09:55:26  brouard
   m[nrl][ncl] -= nll;    (Module): Back to gnuplot.exe instead of wgnuplot.exe
   for (j=ncl+1; j<=nch; j++)  
     m[nrl][j]=m[nrl][j-1]+nlay;    Revision 1.111  2006/01/25 20:38:18  brouard
      (Module): Lots of cleaning and bugs added (Gompertz)
   for (i=nrl+1; i<=nrh; i++) {    (Module): Comments can be added in data file. Missing date values
     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;    can be a simple dot '.'.
     for (j=ncl+1; j<=nch; j++)  
       m[i][j]=m[i][j-1]+nlay;    Revision 1.110  2006/01/25 00:51:50  brouard
   }    (Module): Lots of cleaning and bugs added (Gompertz)
   return m;  
 }    Revision 1.109  2006/01/24 19:37:15  brouard
     (Module): Comments (lines starting with a #) are allowed in data.
 /*************************free ma3x ************************/  
 void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)    Revision 1.108  2006/01/19 18:05:42  lievre
 {    Gnuplot problem appeared...
   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));    To be fixed
   free((FREE_ARG)(m[nrl]+ncl-NR_END));  
   free((FREE_ARG)(m+nrl-NR_END));    Revision 1.107  2006/01/19 16:20:37  brouard
 }    Test existence of gnuplot in imach path
   
 /***************** f1dim *************************/    Revision 1.106  2006/01/19 13:24:36  brouard
 extern int ncom;    Some cleaning and links added in html output
 extern double *pcom,*xicom;  
 extern double (*nrfunc)(double []);    Revision 1.105  2006/01/05 20:23:19  lievre
      *** empty log message ***
 double f1dim(double x)  
 {    Revision 1.104  2005/09/30 16:11:43  lievre
   int j;    (Module): sump fixed, loop imx fixed, and simplifications.
   double f;    (Module): If the status is missing at the last wave but we know
   double *xt;    that the person is alive, then we can code his/her status as -2
      (instead of missing=-1 in earlier versions) and his/her
   xt=vector(1,ncom);    contributions to the likelihood is 1 - Prob of dying from last
   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j];    health status (= 1-p13= p11+p12 in the easiest case of somebody in
   f=(*nrfunc)(xt);    the healthy state at last known wave). Version is 0.98
   free_vector(xt,1,ncom);  
   return f;    Revision 1.103  2005/09/30 15:54:49  lievre
 }    (Module): sump fixed, loop imx fixed, and simplifications.
   
 /*****************brent *************************/    Revision 1.102  2004/09/15 17:31:30  brouard
 double brent(double ax, double bx, double cx, double (*f)(double), double tol,  double *xmin)    Add the possibility to read data file including tab characters.
 {  
   int iter;    Revision 1.101  2004/09/15 10:38:38  brouard
   double a,b,d,etemp;    Fix on curr_time
   double fu,fv,fw,fx;  
   double ftemp;    Revision 1.100  2004/07/12 18:29:06  brouard
   double p,q,r,tol1,tol2,u,v,w,x,xm;    Add version for Mac OS X. Just define UNIX in Makefile
   double e=0.0;  
      Revision 1.99  2004/06/05 08:57:40  brouard
   a=(ax < cx ? ax : cx);    *** empty log message ***
   b=(ax > cx ? ax : cx);  
   x=w=v=bx;    Revision 1.98  2004/05/16 15:05:56  brouard
   fw=fv=fx=(*f)(x);    New version 0.97 . First attempt to estimate force of mortality
   for (iter=1;iter<=ITMAX;iter++) {    directly from the data i.e. without the need of knowing the health
     xm=0.5*(a+b);    state at each age, but using a Gompertz model: log u =a + b*age .
     tol2=2.0*(tol1=tol*fabs(x)+ZEPS);    This is the basic analysis of mortality and should be done before any
     /*          if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/    other analysis, in order to test if the mortality estimated from the
     printf(".");fflush(stdout);    cross-longitudinal survey is different from the mortality estimated
     fprintf(ficlog,".");fflush(ficlog);    from other sources like vital statistic data.
 #ifdef DEBUG  
     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);    The same imach parameter file can be used but the option for mle should be -3.
     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);  
     /*          if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */    Agnès, who wrote this part of the code, tried to keep most of the
 #endif    former routines in order to include the new code within the former code.
     if (fabs(x-xm) <= (tol2-0.5*(b-a))){  
       *xmin=x;    The output is very simple: only an estimate of the intercept and of
       return fx;    the slope with 95% confident intervals.
     }  
     ftemp=fu;    Current limitations:
     if (fabs(e) > tol1) {    A) Even if you enter covariates, i.e. with the
       r=(x-w)*(fx-fv);    model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
       q=(x-v)*(fx-fw);    B) There is no computation of Life Expectancy nor Life Table.
       p=(x-v)*q-(x-w)*r;  
       q=2.0*(q-r);    Revision 1.97  2004/02/20 13:25:42  lievre
       if (q > 0.0) p = -p;    Version 0.96d. Population forecasting command line is (temporarily)
       q=fabs(q);    suppressed.
       etemp=e;  
       e=d;    Revision 1.96  2003/07/15 15:38:55  brouard
       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x))    * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
         d=CGOLD*(e=(x >= xm ? a-x : b-x));    rewritten within the same printf. Workaround: many printfs.
       else {  
         d=p/q;    Revision 1.95  2003/07/08 07:54:34  brouard
         u=x+d;    * imach.c (Repository):
         if (u-a < tol2 || b-u < tol2)    (Repository): Using imachwizard code to output a more meaningful covariance
           d=SIGN(tol1,xm-x);    matrix (cov(a12,c31) instead of numbers.
       }  
     } else {    Revision 1.94  2003/06/27 13:00:02  brouard
       d=CGOLD*(e=(x >= xm ? a-x : b-x));    Just cleaning
     }  
     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d));    Revision 1.93  2003/06/25 16:33:55  brouard
     fu=(*f)(u);    (Module): On windows (cygwin) function asctime_r doesn't
     if (fu <= fx) {    exist so I changed back to asctime which exists.
       if (u >= x) a=x; else b=x;    (Module): Version 0.96b
       SHFT(v,w,x,u)  
         SHFT(fv,fw,fx,fu)    Revision 1.92  2003/06/25 16:30:45  brouard
         } else {    (Module): On windows (cygwin) function asctime_r doesn't
           if (u < x) a=u; else b=u;    exist so I changed back to asctime which exists.
           if (fu <= fw || w == x) {  
             v=w;    Revision 1.91  2003/06/25 15:30:29  brouard
             w=u;    * imach.c (Repository): Duplicated warning errors corrected.
             fv=fw;    (Repository): Elapsed time after each iteration is now output. It
             fw=fu;    helps to forecast when convergence will be reached. Elapsed time
           } else if (fu <= fv || v == x || v == w) {    is stamped in powell.  We created a new html file for the graphs
             v=u;    concerning matrix of covariance. It has extension -cov.htm.
             fv=fu;  
           }    Revision 1.90  2003/06/24 12:34:15  brouard
         }    (Module): Some bugs corrected for windows. Also, when
   }    mle=-1 a template is output in file "or"mypar.txt with the design
   nrerror("Too many iterations in brent");    of the covariance matrix to be input.
   *xmin=x;  
   return fx;    Revision 1.89  2003/06/24 12:30:52  brouard
 }    (Module): Some bugs corrected for windows. Also, when
     mle=-1 a template is output in file "or"mypar.txt with the design
 /****************** mnbrak ***********************/    of the covariance matrix to be input.
   
 void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc,    Revision 1.88  2003/06/23 17:54:56  brouard
             double (*func)(double))    * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
 {  
   double ulim,u,r,q, dum;    Revision 1.87  2003/06/18 12:26:01  brouard
   double fu;    Version 0.96
    
   *fa=(*func)(*ax);    Revision 1.86  2003/06/17 20:04:08  brouard
   *fb=(*func)(*bx);    (Module): Change position of html and gnuplot routines and added
   if (*fb > *fa) {    routine fileappend.
     SHFT(dum,*ax,*bx,dum)  
       SHFT(dum,*fb,*fa,dum)    Revision 1.85  2003/06/17 13:12:43  brouard
       }    * imach.c (Repository): Check when date of death was earlier that
   *cx=(*bx)+GOLD*(*bx-*ax);    current date of interview. It may happen when the death was just
   *fc=(*func)(*cx);    prior to the death. In this case, dh was negative and likelihood
   while (*fb > *fc) {    was wrong (infinity). We still send an "Error" but patch by
     r=(*bx-*ax)*(*fb-*fc);    assuming that the date of death was just one stepm after the
     q=(*bx-*cx)*(*fb-*fa);    interview.
     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/    (Repository): Because some people have very long ID (first column)
       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r));    we changed int to long in num[] and we added a new lvector for
     ulim=(*bx)+GLIMIT*(*cx-*bx);    memory allocation. But we also truncated to 8 characters (left
     if ((*bx-u)*(u-*cx) > 0.0) {    truncation)
       fu=(*func)(u);    (Repository): No more line truncation errors.
     } else if ((*cx-u)*(u-ulim) > 0.0) {  
       fu=(*func)(u);    Revision 1.84  2003/06/13 21:44:43  brouard
       if (fu < *fc) {    * imach.c (Repository): Replace "freqsummary" at a correct
         SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx))    place. It differs from routine "prevalence" which may be called
           SHFT(*fb,*fc,fu,(*func)(u))    many times. Probs is memory consuming and must be used with
           }    parcimony.
     } else if ((u-ulim)*(ulim-*cx) >= 0.0) {    Version 0.95a3 (should output exactly the same maximization than 0.8a2)
       u=ulim;  
       fu=(*func)(u);    Revision 1.83  2003/06/10 13:39:11  lievre
     } else {    *** empty log message ***
       u=(*cx)+GOLD*(*cx-*bx);  
       fu=(*func)(u);    Revision 1.82  2003/06/05 15:57:20  brouard
     }    Add log in  imach.c and  fullversion number is now printed.
     SHFT(*ax,*bx,*cx,u)  
       SHFT(*fa,*fb,*fc,fu)  */
       }  /*
 }     Interpolated Markov Chain
   
 /*************** linmin ************************/    Short summary of the programme:
     
 int ncom;    This program computes Healthy Life Expectancies from
 double *pcom,*xicom;    cross-longitudinal data. Cross-longitudinal data consist in: -1- a
 double (*nrfunc)(double []);    first survey ("cross") where individuals from different ages are
      interviewed on their health status or degree of disability (in the
 void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []))    case of a health survey which is our main interest) -2- at least a
 {    second wave of interviews ("longitudinal") which measure each change
   double brent(double ax, double bx, double cx,    (if any) in individual health status.  Health expectancies are
                double (*f)(double), double tol, double *xmin);    computed from the time spent in each health state according to a
   double f1dim(double x);    model. More health states you consider, more time is necessary to reach the
   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb,    Maximum Likelihood of the parameters involved in the model.  The
               double *fc, double (*func)(double));    simplest model is the multinomial logistic model where pij is the
   int j;    probability to be observed in state j at the second wave
   double xx,xmin,bx,ax;    conditional to be observed in state i at the first wave. Therefore
   double fx,fb,fa;    the model is: log(pij/pii)= aij + bij*age+ cij*sex + etc , where
      'age' is age and 'sex' is a covariate. If you want to have a more
   ncom=n;    complex model than "constant and age", you should modify the program
   pcom=vector(1,n);    where the markup *Covariates have to be included here again* invites
   xicom=vector(1,n);    you to do it.  More covariates you add, slower the
   nrfunc=func;    convergence.
   for (j=1;j<=n;j++) {  
     pcom[j]=p[j];    The advantage of this computer programme, compared to a simple
     xicom[j]=xi[j];    multinomial logistic model, is clear when the delay between waves is not
   }    identical for each individual. Also, if a individual missed an
   ax=0.0;    intermediate interview, the information is lost, but taken into
   xx=1.0;    account using an interpolation or extrapolation.  
   mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  
   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin);    hPijx is the probability to be observed in state i at age x+h
 #ifdef DEBUG    conditional to the observed state i at age x. The delay 'h' can be
   printf("retour brent fret=%.12e xmin=%.12e\n",*fret,xmin);    split into an exact number (nh*stepm) of unobserved intermediate
   fprintf(ficlog,"retour brent fret=%.12e xmin=%.12e\n",*fret,xmin);    states. This elementary transition (by month, quarter,
 #endif    semester or year) is modelled as a multinomial logistic.  The hPx
   for (j=1;j<=n;j++) {    matrix is simply the matrix product of nh*stepm elementary matrices
     xi[j] *= xmin;    and the contribution of each individual to the likelihood is simply
     p[j] += xi[j];    hPijx.
   }  
   free_vector(xicom,1,n);    Also this programme outputs the covariance matrix of the parameters but also
   free_vector(pcom,1,n);    of the life expectancies. It also computes the period (stable) prevalence. 
 }    
     Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
 /*************** powell ************************/             Institut national d'études démographiques, Paris.
 void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret,    This software have been partly granted by Euro-REVES, a concerted action
             double (*func)(double []))    from the European Union.
 {    It is copyrighted identically to a GNU software product, ie programme and
   void linmin(double p[], double xi[], int n, double *fret,    software can be distributed freely for non commercial use. Latest version
               double (*func)(double []));    can be accessed at http://euroreves.ined.fr/imach .
   int i,ibig,j;  
   double del,t,*pt,*ptt,*xit;    Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
   double fp,fptt;    or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
   double *xits;    
   pt=vector(1,n);    **********************************************************************/
   ptt=vector(1,n);  /*
   xit=vector(1,n);    main
   xits=vector(1,n);    read parameterfile
   *fret=(*func)(p);    read datafile
   for (j=1;j<=n;j++) pt[j]=p[j];    concatwav
   for (*iter=1;;++(*iter)) {    freqsummary
     fp=(*fret);    if (mle >= 1)
     ibig=0;      mlikeli
     del=0.0;    print results files
     printf("\nPowell iter=%d -2*LL=%.12f",*iter,*fret);    if mle==1 
     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f",*iter,*fret);       computes hessian
     for (i=1;i<=n;i++)    read end of parameter file: agemin, agemax, bage, fage, estepm
       printf(" %d %.12f",i, p[i]);        begin-prev-date,...
     fprintf(ficlog," %d %.12f",i, p[i]);    open gnuplot file
     printf("\n");    open html file
     fprintf(ficlog,"\n");    period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
     for (i=1;i<=n;i++) {     for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
       for (j=1;j<=n;j++) xit[j]=xi[j][i];                                    | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
       fptt=(*fret);      freexexit2 possible for memory heap.
 #ifdef DEBUG  
       printf("fret=%lf \n",*fret);    h Pij x                         | pij_nom  ficrestpij
       fprintf(ficlog,"fret=%lf \n",*fret);     # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
 #endif         1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
       printf("%d",i);fflush(stdout);         1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
       fprintf(ficlog,"%d",i);fflush(ficlog);  
       linmin(p,xit,n,fret,func);         1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
       if (fabs(fptt-(*fret)) > del) {         1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
         del=fabs(fptt-(*fret));    variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
         ibig=i;     Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
       }     Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
 #ifdef DEBUG  
       printf("%d %.12e",i,(*fret));    forecasting if prevfcast==1 prevforecast call prevalence()
       fprintf(ficlog,"%d %.12e",i,(*fret));    health expectancies
       for (j=1;j<=n;j++) {    Variance-covariance of DFLE
         xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);    prevalence()
         printf(" x(%d)=%.12e",j,xit[j]);     movingaverage()
         fprintf(ficlog," x(%d)=%.12e",j,xit[j]);    varevsij() 
       }    if popbased==1 varevsij(,popbased)
       for(j=1;j<=n;j++) {    total life expectancies
         printf(" p=%.12e",p[j]);    Variance of period (stable) prevalence
         fprintf(ficlog," p=%.12e",p[j]);   end
       }  */
       printf("\n");  
       fprintf(ficlog,"\n");  /* #define DEBUG */
 #endif  /* #define DEBUGBRENT */
     }  #define POWELL /* Instead of NLOPT */
     if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) {  #define POWELLF1F3 /* Skip test */
 #ifdef DEBUG  /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
       int k[2],l;  /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
       k[0]=1;  
       k[1]=-1;  #include <math.h>
       printf("Max: %.12e",(*func)(p));  #include <stdio.h>
       fprintf(ficlog,"Max: %.12e",(*func)(p));  #include <stdlib.h>
       for (j=1;j<=n;j++) {  #include <string.h>
         printf(" %.12e",p[j]);  
         fprintf(ficlog," %.12e",p[j]);  #ifdef _WIN32
       }  #include <io.h>
       printf("\n");  #include <windows.h>
       fprintf(ficlog,"\n");  #include <tchar.h>
       for(l=0;l<=1;l++) {  #else
         for (j=1;j<=n;j++) {  #include <unistd.h>
           ptt[j]=p[j]+(p[j]-pt[j])*k[l];  #endif
           printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);  
           fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);  #include <limits.h>
         }  #include <sys/types.h>
         printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));  
         fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));  #if defined(__GNUC__)
       }  #include <sys/utsname.h> /* Doesn't work on Windows */
 #endif  #endif
   
   #include <sys/stat.h>
       free_vector(xit,1,n);  #include <errno.h>
       free_vector(xits,1,n);  /* extern int errno; */
       free_vector(ptt,1,n);  
       free_vector(pt,1,n);  /* #ifdef LINUX */
       return;  /* #include <time.h> */
     }  /* #include "timeval.h" */
     if (*iter == ITMAX) nrerror("powell exceeding maximum iterations.");  /* #else */
     for (j=1;j<=n;j++) {  /* #include <sys/time.h> */
       ptt[j]=2.0*p[j]-pt[j];  /* #endif */
       xit[j]=p[j]-pt[j];  
       pt[j]=p[j];  #include <time.h>
     }  
     fptt=(*func)(ptt);  #ifdef GSL
     if (fptt < fp) {  #include <gsl/gsl_errno.h>
       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt);  #include <gsl/gsl_multimin.h>
       if (t < 0.0) {  #endif
         linmin(p,xit,n,fret,func);  
         for (j=1;j<=n;j++) {  
           xi[j][ibig]=xi[j][n];  #ifdef NLOPT
           xi[j][n]=xit[j];  #include <nlopt.h>
         }  typedef struct {
 #ifdef DEBUG    double (* function)(double [] );
         printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);  } myfunc_data ;
         fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);  #endif
         for(j=1;j<=n;j++){  
           printf(" %.12e",xit[j]);  /* #include <libintl.h> */
           fprintf(ficlog," %.12e",xit[j]);  /* #define _(String) gettext (String) */
         }  
         printf("\n");  #define MAXLINE 1024 /* Was 256. Overflow with 312 with 2 states and 4 covariates. Should be ok */
         fprintf(ficlog,"\n");  
 #endif  #define GNUPLOTPROGRAM "gnuplot"
       }  /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
     }  #define FILENAMELENGTH 132
   }  
 }  #define GLOCK_ERROR_NOPATH              -1      /* empty path */
   #define GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
 /**** Prevalence limit ****************/  
   #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
 double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int ij)  #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
 {  
   /* Computes the prevalence limit in each live state at age x by left multiplying the unit  #define NINTERVMAX 8
      matrix by transitions matrix until convergence is reached */  #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
   #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
   int i, ii,j,k;  #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
   double min, max, maxmin, maxmax,sumnew=0.;  #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
   double **matprod2();  #define MAXN 20000
   double **out, cov[NCOVMAX], **pmij();  #define YEARM 12. /**< Number of months per year */
   double **newm;  #define AGESUP 130
   double agefin, delaymax=50 ; /* Max number of years to converge */  #define AGEBASE 40
   #define AGEOVERFLOW 1.e20
   for (ii=1;ii<=nlstate+ndeath;ii++)  #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
     for (j=1;j<=nlstate+ndeath;j++){  #ifdef _WIN32
       oldm[ii][j]=(ii==j ? 1.0 : 0.0);  #define DIRSEPARATOR '\\'
     }  #define CHARSEPARATOR "\\"
   #define ODIRSEPARATOR '/'
    cov[1]=1.;  #else
    #define DIRSEPARATOR '/'
  /* Even if hstepm = 1, at least one multiplication by the unit matrix */  #define CHARSEPARATOR "/"
   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){  #define ODIRSEPARATOR '\\'
     newm=savm;  #endif
     /* Covariates have to be included here again */  
      cov[2]=agefin;  /* $Id$ */
    /* $State$ */
       for (k=1; k<=cptcovn;k++) {  #include "version.h"
         cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]];  char version[]=__IMACH_VERSION__;
         /*      printf("ij=%d k=%d Tvar[k]=%d nbcode=%d cov=%lf codtab[ij][Tvar[k]]=%d \n",ij,k, Tvar[k],nbcode[Tvar[k]][codtab[ij][Tvar[k]]],cov[2+k], codtab[ij][Tvar[k]]);*/  char copyright[]="September 2015,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015";
       }  char fullversion[]="$Revision$ $Date$"; 
       for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];  char strstart[80];
       for (k=1; k<=cptcovprod;k++)  char optionfilext[10], optionfilefiname[FILENAMELENGTH];
         cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];  int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
   int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
       /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/  /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
       /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/  int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
       /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/  int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);  int cptcovs=0; /**< cptcovs number of simple covariates V2+V1 =2 */
   int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
     savm=oldm;  int cptcovprodnoage=0; /**< Number of covariate products without age */   
     oldm=newm;  int cptcoveff=0; /* Total number of covariates to vary for printing results */
     maxmax=0.;  int cptcov=0; /* Working variable */
     for(j=1;j<=nlstate;j++){  int npar=NPARMAX;
       min=1.;  int nlstate=2; /* Number of live states */
       max=0.;  int ndeath=1; /* Number of dead states */
       for(i=1; i<=nlstate; i++) {  int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
         sumnew=0;  int popbased=0;
         for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];  
         prlim[i][j]= newm[i][j]/(1-sumnew);  int *wav; /* Number of waves for this individuual 0 is possible */
         max=FMAX(max,prlim[i][j]);  int maxwav=0; /* Maxim number of waves */
         min=FMIN(min,prlim[i][j]);  int jmin=0, jmax=0; /* min, max spacing between 2 waves */
       }  int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
       maxmin=max-min;  int gipmx=0, gsw=0; /* Global variables on the number of contributions 
       maxmax=FMAX(maxmax,maxmin);                     to the likelihood and the sum of weights (done by funcone)*/
     }  int mle=1, weightopt=0;
     if(maxmax < ftolpl){  int **mw; /* mw[mi][i] is number of the mi wave for this individual */
       return prlim;  int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
     }  int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
   }             * wave mi and wave mi+1 is not an exact multiple of stepm. */
 }  int countcallfunc=0;  /* Count the number of calls to func */
   double jmean=1; /* Mean space between 2 waves */
 /*************** transition probabilities ***************/  double **matprod2(); /* test */
   double **oldm, **newm, **savm; /* Working pointers to matrices */
 double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )  double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
 {  /*FILE *fic ; */ /* Used in readdata only */
   double s1, s2;  FILE *ficpar, *ficparo,*ficres, *ficresp, *ficrespl, *ficrespij, *ficrest,*ficresf,*ficrespop;
   /*double t34;*/  FILE *ficlog, *ficrespow;
   int i,j,j1, nc, ii, jj;  int globpr=0; /* Global variable for printing or not */
   double fretone; /* Only one call to likelihood */
     for(i=1; i<= nlstate; i++){  long ipmx=0; /* Number of contributions */
     for(j=1; j<i;j++){  double sw; /* Sum of weights */
       for (nc=1, s2=0.;nc <=ncovmodel; nc++){  char filerespow[FILENAMELENGTH];
         /*s2 += param[i][j][nc]*cov[nc];*/  char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
         s2 += x[(i-1)*nlstate*ncovmodel+(j-1)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];  FILE *ficresilk;
         /*printf("Int j<i s1=%.17e, s2=%.17e\n",s1,s2);*/  FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
       }  FILE *ficresprobmorprev;
       ps[i][j]=s2;  FILE *fichtm, *fichtmcov; /* Html File */
       /*printf("s1=%.17e, s2=%.17e\n",s1,s2);*/  FILE *ficreseij;
     }  char filerese[FILENAMELENGTH];
     for(j=i+1; j<=nlstate+ndeath;j++){  FILE *ficresstdeij;
       for (nc=1, s2=0.;nc <=ncovmodel; nc++){  char fileresstde[FILENAMELENGTH];
         s2 += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];  FILE *ficrescveij;
         /*printf("Int j>i s1=%.17e, s2=%.17e %lx %lx\n",s1,s2,s1,s2);*/  char filerescve[FILENAMELENGTH];
       }  FILE  *ficresvij;
       ps[i][j]=s2;  char fileresv[FILENAMELENGTH];
     }  FILE  *ficresvpl;
   }  char fileresvpl[FILENAMELENGTH];
     /*ps[3][2]=1;*/  char title[MAXLINE];
   char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH];
   for(i=1; i<= nlstate; i++){  char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
      s1=0;  char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
     for(j=1; j<i; j++)  char command[FILENAMELENGTH];
       s1+=exp(ps[i][j]);  int  outcmd=0;
     for(j=i+1; j<=nlstate+ndeath; j++)  
       s1+=exp(ps[i][j]);  char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
     ps[i][i]=1./(s1+1.);  char fileresu[FILENAMELENGTH]; /* Without r in front */
     for(j=1; j<i; j++)  char filelog[FILENAMELENGTH]; /* Log file */
       ps[i][j]= exp(ps[i][j])*ps[i][i];  char filerest[FILENAMELENGTH];
     for(j=i+1; j<=nlstate+ndeath; j++)  char fileregp[FILENAMELENGTH];
       ps[i][j]= exp(ps[i][j])*ps[i][i];  char popfile[FILENAMELENGTH];
     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */  
   } /* end i */  char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
   
   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){  /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
     for(jj=1; jj<= nlstate+ndeath; jj++){  /* struct timezone tzp; */
       ps[ii][jj]=0;  /* extern int gettimeofday(); */
       ps[ii][ii]=1;  struct tm tml, *gmtime(), *localtime();
     }  
   }  extern time_t time();
   
   struct tm start_time, end_time, curr_time, last_time, forecast_time;
   /*   for(ii=1; ii<= nlstate+ndeath; ii++){  time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
     for(jj=1; jj<= nlstate+ndeath; jj++){  struct tm tm;
      printf("%lf ",ps[ii][jj]);  
    }  char strcurr[80], strfor[80];
     printf("\n ");  
     }  char *endptr;
     printf("\n ");printf("%lf ",cov[2]);*/  long lval;
 /*  double dval;
   for(i=1; i<= npar; i++) printf("%f ",x[i]);  
   goto end;*/  #define NR_END 1
     return ps;  #define FREE_ARG char*
 }  #define FTOL 1.0e-10
   
 /**************** Product of 2 matrices ******************/  #define NRANSI 
   #define ITMAX 200 
 double **matprod2(double **out, double **in,long nrl, long nrh, long ncl, long nch, long ncolol, long ncoloh, double **b)  
 {  #define TOL 2.0e-4 
   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times  
      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */  #define CGOLD 0.3819660 
   /* in, b, out are matrice of pointers which should have been initialized  #define ZEPS 1.0e-10 
      before: only the contents of out is modified. The function returns  #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
      a pointer to pointers identical to out */  
   long i, j, k;  #define GOLD 1.618034 
   for(i=nrl; i<= nrh; i++)  #define GLIMIT 100.0 
     for(k=ncolol; k<=ncoloh; k++)  #define TINY 1.0e-20 
       for(j=ncl,out[i][k]=0.; j<=nch; j++)  
         out[i][k] +=in[i][j]*b[j][k];  static double maxarg1,maxarg2;
   #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
   return out;  #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
 }    
   #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
   #define rint(a) floor(a+0.5)
 /************* Higher Matrix Product ***************/  /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
   #define mytinydouble 1.0e-16
 double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij )  /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
 {  /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
   /* Computes the transition matrix starting at age 'age' over 'nhstepm*hstepm*stepm' month  /* static double dsqrarg; */
      duration (i.e. until  /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
      age (in years)  age+nhstepm*stepm/12) by multiplying nhstepm*hstepm matrices.  static double sqrarg;
      Output is stored in matrix po[i][j][h] for h every 'hstepm' step  #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
      (typically every 2 years instead of every month which is too big).  #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
      Model is determined by parameters x and covariates have to be  int agegomp= AGEGOMP;
      included manually here.  
   int imx; 
      */  int stepm=1;
   /* Stepm, step in month: minimum step interpolation*/
   int i, j, d, h, k;  
   double **out, cov[NCOVMAX];  int estepm;
   double **newm;  /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
   
   /* Hstepm could be zero and should return the unit matrix */  int m,nb;
   for (i=1;i<=nlstate+ndeath;i++)  long *num;
     for (j=1;j<=nlstate+ndeath;j++){  int firstpass=0, lastpass=4,*cod, *cens;
       oldm[i][j]=(i==j ? 1.0 : 0.0);  int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
       po[i][j][0]=(i==j ? 1.0 : 0.0);                     covariate for which somebody answered excluding 
     }                     undefined. Usually 2: 0 and 1. */
   /* Even if hstepm = 1, at least one multiplication by the unit matrix */  int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
   for(h=1; h <=nhstepm; h++){                               covariate for which somebody answered including 
     for(d=1; d <=hstepm; d++){                               undefined. Usually 3: -1, 0 and 1. */
       newm=savm;  double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
       /* Covariates have to be included here again */  double **pmmij, ***probs;
       cov[1]=1.;  double *ageexmed,*agecens;
       cov[2]=age+((h-1)*hstepm + (d-1))*stepm/YEARM;  double dateintmean=0;
       for (k=1; k<=cptcovn;k++) cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]];  
       for (k=1; k<=cptcovage;k++)  double *weight;
         cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];  int **s; /* Status */
       for (k=1; k<=cptcovprod;k++)  double *agedc;
         cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];  double  **covar; /**< covar[j,i], value of jth covariate for individual i,
                     * covar=matrix(0,NCOVMAX,1,n); 
                     * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/  double  idx; 
       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/  int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,  int *Tage;
                    pmij(pmmij,cov,ncovmodel,x,nlstate));  int *Ndum; /** Freq of modality (tricode */
       savm=oldm;  /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
       oldm=newm;  int **Tvard, *Tprod, cptcovprod, *Tvaraff;
     }  double *lsurv, *lpop, *tpop;
     for(i=1; i<=nlstate+ndeath; i++)  
       for(j=1;j<=nlstate+ndeath;j++) {  double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
         po[i][j][h]=newm[i][j];  double ftolhess; /**< Tolerance for computing hessian */
         /*printf("i=%d j=%d h=%d po[i][j][h]=%f ",i,j,h,po[i][j][h]);  
          */  /**************** split *************************/
       }  static  int split( char *path, char *dirc, char *name, char *ext, char *finame )
   } /* end h */  {
   return po;    /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
 }       the name of the file (name), its extension only (ext) and its first part of the name (finame)
     */ 
     char  *ss;                            /* pointer */
 /*************** log-likelihood *************/    int   l1=0, l2=0;                             /* length counters */
 double func( double *x)  
 {    l1 = strlen(path );                   /* length of path */
   int i, ii, j, k, mi, d, kk;    if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
   double l, ll[NLSTATEMAX], cov[NCOVMAX];    ss= strrchr( path, DIRSEPARATOR );            /* find last / */
   double **out;    if ( ss == NULL ) {                   /* no directory, so determine current directory */
   double sw; /* Sum of weights */      strcpy( name, path );               /* we got the fullname name because no directory */
   double lli; /* Individual log likelihood */      /*if(strrchr(path, ODIRSEPARATOR )==NULL)
   long ipmx;        printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
   /*extern weight */      /* get current working directory */
   /* We are differentiating ll according to initial status */      /*    extern  char* getcwd ( char *buf , int len);*/
   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/  #ifdef WIN32
   /*for(i=1;i<imx;i++)      if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
     printf(" %d\n",s[4][i]);  #else
   */          if (getcwd(dirc, FILENAME_MAX) == NULL) {
   cov[1]=1.;  #endif
         return( GLOCK_ERROR_GETCWD );
   for(k=1; k<=nlstate; k++) ll[k]=0.;      }
   for (i=1,ipmx=0, sw=0.; i<=imx; i++){      /* got dirc from getcwd*/
     for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];      printf(" DIRC = %s \n",dirc);
     for(mi=1; mi<= wav[i]-1; mi++){    } else {                              /* strip direcotry from path */
       for (ii=1;ii<=nlstate+ndeath;ii++)      ss++;                               /* after this, the filename */
         for (j=1;j<=nlstate+ndeath;j++) oldm[ii][j]=(ii==j ? 1.0 : 0.0);      l2 = strlen( ss );                  /* length of filename */
       for(d=0; d<dh[mi][i]; d++){      if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
         newm=savm;      strcpy( name, ss );         /* save file name */
         cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;      strncpy( dirc, path, l1 - l2 );     /* now the directory */
         for (kk=1; kk<=cptcovage;kk++) {      dirc[l1-l2] = '\0';                 /* add zero */
           cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];      printf(" DIRC2 = %s \n",dirc);
         }    }
            /* We add a separator at the end of dirc if not exists */
         out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,    l1 = strlen( dirc );                  /* length of directory */
                      1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));    if( dirc[l1-1] != DIRSEPARATOR ){
         savm=oldm;      dirc[l1] =  DIRSEPARATOR;
         oldm=newm;      dirc[l1+1] = 0; 
              printf(" DIRC3 = %s \n",dirc);
            }
       } /* end mult */    ss = strrchr( name, '.' );            /* find last / */
          if (ss >0){
       lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);      ss++;
       /* printf(" %f ",out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/      strcpy(ext,ss);                     /* save extension */
       ipmx +=1;      l1= strlen( name);
       sw += weight[i];      l2= strlen(ss)+1;
       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;      strncpy( finame, name, l1-l2);
     } /* end of wave */      finame[l1-l2]= 0;
   } /* end of individual */    }
   
   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];    return( 0 );                          /* we're done */
   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */  }
   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */  
   return -l;  
 }  /******************************************/
   
   void replace_back_to_slash(char *s, char*t)
 /*********** Maximum Likelihood Estimation ***************/  {
     int i;
 void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))    int lg=0;
 {    i=0;
   int i,j, iter;    lg=strlen(t);
   double **xi,*delti;    for(i=0; i<= lg; i++) {
   double fret;      (s[i] = t[i]);
   xi=matrix(1,npar,1,npar);      if (t[i]== '\\') s[i]='/';
   for (i=1;i<=npar;i++)    }
     for (j=1;j<=npar;j++)  }
       xi[i][j]=(i==j ? 1.0 : 0.0);  
   printf("Powell\n");  fprintf(ficlog,"Powell\n");  char *trimbb(char *out, char *in)
   powell(p,xi,npar,ftol,&iter,&fret,func);  { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
     char *s;
    printf("\n#Number of iterations = %d, -2 Log likelihood = %.12f\n",iter,func(p));    s=out;
   fprintf(ficlog,"#Number of iterations = %d, -2 Log likelihood = %.12f \n",iter,func(p));    while (*in != '\0'){
   fprintf(ficres,"#Number of iterations = %d, -2 Log likelihood = %.12f \n",iter,func(p));      while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
         in++;
 }      }
       *out++ = *in++;
 /**** Computes Hessian and covariance matrix ***/    }
 void hesscov(double **matcov, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))    *out='\0';
 {    return s;
   double  **a,**y,*x,pd;  }
   double **hess;  
   int i, j,jk;  /* char *substrchaine(char *out, char *in, char *chain) */
   int *indx;  /* { */
   /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
   double hessii(double p[], double delta, int theta, double delti[]);  /*   char *s, *t; */
   double hessij(double p[], double delti[], int i, int j);  /*   t=in;s=out; */
   void lubksb(double **a, int npar, int *indx, double b[]) ;  /*   while ((*in != *chain) && (*in != '\0')){ */
   void ludcmp(double **a, int npar, int *indx, double *d) ;  /*     *out++ = *in++; */
   /*   } */
   hess=matrix(1,npar,1,npar);  
   /*   /\* *in matches *chain *\/ */
   printf("\nCalculation of the hessian matrix. Wait...\n");  /*   while ((*in++ == *chain++) && (*in != '\0')){ */
   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");  /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
   for (i=1;i<=npar;i++){  /*   } */
     printf("%d",i);fflush(stdout);  /*   in--; chain--; */
     fprintf(ficlog,"%d",i);fflush(ficlog);  /*   while ( (*in != '\0')){ */
     hess[i][i]=hessii(p,ftolhess,i,delti);  /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
     /*printf(" %f ",p[i]);*/  /*     *out++ = *in++; */
     /*printf(" %lf ",hess[i][i]);*/  /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
   }  /*   } */
    /*   *out='\0'; */
   for (i=1;i<=npar;i++) {  /*   out=s; */
     for (j=1;j<=npar;j++)  {  /*   return out; */
       if (j>i) {  /* } */
         printf(".%d%d",i,j);fflush(stdout);  char *substrchaine(char *out, char *in, char *chain)
         fprintf(ficlog,".%d%d",i,j);fflush(ficlog);  {
         hess[i][j]=hessij(p,delti,i,j);    /* Substract chain 'chain' from 'in', return and output 'out' */
         hess[j][i]=hess[i][j];        /* in="V1+V1*age+age*age+V2", chain="age*age" */
         /*printf(" %lf ",hess[i][j]);*/  
       }    char *strloc;
     }  
   }    strcpy (out, in); 
   printf("\n");    strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
   fprintf(ficlog,"\n");    printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
     if(strloc != NULL){ 
   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");      /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");      memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
        /* strcpy (strloc, strloc +strlen(chain));*/
   a=matrix(1,npar,1,npar);    }
   y=matrix(1,npar,1,npar);    printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
   x=vector(1,npar);    return out;
   indx=ivector(1,npar);  }
   for (i=1;i<=npar;i++)  
     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];  
   ludcmp(a,npar,indx,&pd);  char *cutl(char *blocc, char *alocc, char *in, char occ)
   {
   for (j=1;j<=npar;j++) {    /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
     for (i=1;i<=npar;i++) x[i]=0;       and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
     x[j]=1;       gives blocc="abcdef" and alocc="ghi2j".
     lubksb(a,npar,indx,x);       If occ is not found blocc is null and alocc is equal to in. Returns blocc
     for (i=1;i<=npar;i++){    */
       matcov[i][j]=x[i];    char *s, *t;
     }    t=in;s=in;
   }    while ((*in != occ) && (*in != '\0')){
       *alocc++ = *in++;
   printf("\n#Hessian matrix#\n");    }
   fprintf(ficlog,"\n#Hessian matrix#\n");    if( *in == occ){
   for (i=1;i<=npar;i++) {      *(alocc)='\0';
     for (j=1;j<=npar;j++) {      s=++in;
       printf("%.3e ",hess[i][j]);    }
       fprintf(ficlog,"%.3e ",hess[i][j]);   
     }    if (s == t) {/* occ not found */
     printf("\n");      *(alocc-(in-s))='\0';
     fprintf(ficlog,"\n");      in=s;
   }    }
     while ( *in != '\0'){
   /* Recompute Inverse */      *blocc++ = *in++;
   for (i=1;i<=npar;i++)    }
     for (j=1;j<=npar;j++) a[i][j]=matcov[i][j];  
   ludcmp(a,npar,indx,&pd);    *blocc='\0';
     return t;
   /*  printf("\n#Hessian matrix recomputed#\n");  }
   char *cutv(char *blocc, char *alocc, char *in, char occ)
   for (j=1;j<=npar;j++) {  {
     for (i=1;i<=npar;i++) x[i]=0;    /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
     x[j]=1;       and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
     lubksb(a,npar,indx,x);       gives blocc="abcdef2ghi" and alocc="j".
     for (i=1;i<=npar;i++){       If occ is not found blocc is null and alocc is equal to in. Returns alocc
       y[i][j]=x[i];    */
       printf("%.3e ",y[i][j]);    char *s, *t;
       fprintf(ficlog,"%.3e ",y[i][j]);    t=in;s=in;
     }    while (*in != '\0'){
     printf("\n");      while( *in == occ){
     fprintf(ficlog,"\n");        *blocc++ = *in++;
   }        s=in;
   */      }
       *blocc++ = *in++;
   free_matrix(a,1,npar,1,npar);    }
   free_matrix(y,1,npar,1,npar);    if (s == t) /* occ not found */
   free_vector(x,1,npar);      *(blocc-(in-s))='\0';
   free_ivector(indx,1,npar);    else
   free_matrix(hess,1,npar,1,npar);      *(blocc-(in-s)-1)='\0';
     in=s;
     while ( *in != '\0'){
 }      *alocc++ = *in++;
     }
 /*************** hessian matrix ****************/  
 double hessii( double x[], double delta, int theta, double delti[])    *alocc='\0';
 {    return s;
   int i;  }
   int l=1, lmax=20;  
   double k1,k2;  int nbocc(char *s, char occ)
   double p2[NPARMAX+1];  {
   double res;    int i,j=0;
   double delt, delts, nkhi=10.,nkhif=1., khi=1.e-4;    int lg=20;
   double fx;    i=0;
   int k=0,kmax=10;    lg=strlen(s);
   double l1;    for(i=0; i<= lg; i++) {
     if  (s[i] == occ ) j++;
   fx=func(x);    }
   for (i=1;i<=npar;i++) p2[i]=x[i];    return j;
   for(l=0 ; l <=lmax; l++){  }
     l1=pow(10,l);  
     delts=delt;  /* void cutv(char *u,char *v, char*t, char occ) */
     for(k=1 ; k <kmax; k=k+1){  /* { */
       delt = delta*(l1*k);  /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
       p2[theta]=x[theta] +delt;  /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
       k1=func(p2)-fx;  /*      gives u="abcdef2ghi" and v="j" *\/ */
       p2[theta]=x[theta]-delt;  /*   int i,lg,j,p=0; */
       k2=func(p2)-fx;  /*   i=0; */
       /*res= (k1-2.0*fx+k2)/delt/delt; */  /*   lg=strlen(t); */
       res= (k1+k2)/delt/delt/2.; /* Divided by because L and not 2*L */  /*   for(j=0; j<=lg-1; j++) { */
        /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
 #ifdef DEBUG  /*   } */
       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);  
       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);  /*   for(j=0; j<p; j++) { */
 #endif  /*     (u[j] = t[j]); */
       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */  /*   } */
       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){  /*      u[p]='\0'; */
         k=kmax;  
       }  /*    for(j=0; j<= lg; j++) { */
       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */  /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
         k=kmax; l=lmax*10.;  /*   } */
       }  /* } */
       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  
         delts=delt;  #ifdef _WIN32
       }  char * strsep(char **pp, const char *delim)
     }  {
   }    char *p, *q;
   delti[theta]=delts;           
   return res;    if ((p = *pp) == NULL)
        return 0;
 }    if ((q = strpbrk (p, delim)) != NULL)
     {
 double hessij( double x[], double delti[], int thetai,int thetaj)      *pp = q + 1;
 {      *q = '\0';
   int i;    }
   int l=1, l1, lmax=20;    else
   double k1,k2,k3,k4,res,fx;      *pp = 0;
   double p2[NPARMAX+1];    return p;
   int k;  }
   #endif
   fx=func(x);  
   for (k=1; k<=2; k++) {  /********************** nrerror ********************/
     for (i=1;i<=npar;i++) p2[i]=x[i];  
     p2[thetai]=x[thetai]+delti[thetai]/k;  void nrerror(char error_text[])
     p2[thetaj]=x[thetaj]+delti[thetaj]/k;  {
     k1=func(p2)-fx;    fprintf(stderr,"ERREUR ...\n");
      fprintf(stderr,"%s\n",error_text);
     p2[thetai]=x[thetai]+delti[thetai]/k;    exit(EXIT_FAILURE);
     p2[thetaj]=x[thetaj]-delti[thetaj]/k;  }
     k2=func(p2)-fx;  /*********************** vector *******************/
    double *vector(int nl, int nh)
     p2[thetai]=x[thetai]-delti[thetai]/k;  {
     p2[thetaj]=x[thetaj]+delti[thetaj]/k;    double *v;
     k3=func(p2)-fx;    v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
      if (!v) nrerror("allocation failure in vector");
     p2[thetai]=x[thetai]-delti[thetai]/k;    return v-nl+NR_END;
     p2[thetaj]=x[thetaj]-delti[thetaj]/k;  }
     k4=func(p2)-fx;  
     res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /* Because of L not 2*L */  /************************ free vector ******************/
 #ifdef DEBUG  void free_vector(double*v, int nl, int nh)
     printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);  {
     fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);    free((FREE_ARG)(v+nl-NR_END));
 #endif  }
   }  
   return res;  /************************ivector *******************************/
 }  int *ivector(long nl,long nh)
   {
 /************** Inverse of matrix **************/    int *v;
 void ludcmp(double **a, int n, int *indx, double *d)    v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
 {    if (!v) nrerror("allocation failure in ivector");
   int i,imax,j,k;    return v-nl+NR_END;
   double big,dum,sum,temp;  }
   double *vv;  
    /******************free ivector **************************/
   vv=vector(1,n);  void free_ivector(int *v, long nl, long nh)
   *d=1.0;  {
   for (i=1;i<=n;i++) {    free((FREE_ARG)(v+nl-NR_END));
     big=0.0;  }
     for (j=1;j<=n;j++)  
       if ((temp=fabs(a[i][j])) > big) big=temp;  /************************lvector *******************************/
     if (big == 0.0) nrerror("Singular matrix in routine ludcmp");  long *lvector(long nl,long nh)
     vv[i]=1.0/big;  {
   }    long *v;
   for (j=1;j<=n;j++) {    v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
     for (i=1;i<j;i++) {    if (!v) nrerror("allocation failure in ivector");
       sum=a[i][j];    return v-nl+NR_END;
       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j];  }
       a[i][j]=sum;  
     }  /******************free lvector **************************/
     big=0.0;  void free_lvector(long *v, long nl, long nh)
     for (i=j;i<=n;i++) {  {
       sum=a[i][j];    free((FREE_ARG)(v+nl-NR_END));
       for (k=1;k<j;k++)  }
         sum -= a[i][k]*a[k][j];  
       a[i][j]=sum;  /******************* imatrix *******************************/
       if ( (dum=vv[i]*fabs(sum)) >= big) {  int **imatrix(long nrl, long nrh, long ncl, long nch) 
         big=dum;       /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
         imax=i;  { 
       }    long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
     }    int **m; 
     if (j != imax) {    
       for (k=1;k<=n;k++) {    /* allocate pointers to rows */ 
         dum=a[imax][k];    m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
         a[imax][k]=a[j][k];    if (!m) nrerror("allocation failure 1 in matrix()"); 
         a[j][k]=dum;    m += NR_END; 
       }    m -= nrl; 
       *d = -(*d);    
       vv[imax]=vv[j];    
     }    /* allocate rows and set pointers to them */ 
     indx[j]=imax;    m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
     if (a[j][j] == 0.0) a[j][j]=TINY;    if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
     if (j != n) {    m[nrl] += NR_END; 
       dum=1.0/(a[j][j]);    m[nrl] -= ncl; 
       for (i=j+1;i<=n;i++) a[i][j] *= dum;    
     }    for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
   }    
   free_vector(vv,1,n);  /* Doesn't work */    /* return pointer to array of pointers to rows */ 
 ;    return m; 
 }  } 
   
 void lubksb(double **a, int n, int *indx, double b[])  /****************** free_imatrix *************************/
 {  void free_imatrix(m,nrl,nrh,ncl,nch)
   int i,ii=0,ip,j;        int **m;
   double sum;        long nch,ncl,nrh,nrl; 
         /* free an int matrix allocated by imatrix() */ 
   for (i=1;i<=n;i++) {  { 
     ip=indx[i];    free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
     sum=b[ip];    free((FREE_ARG) (m+nrl-NR_END)); 
     b[ip]=b[i];  } 
     if (ii)  
       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j];  /******************* matrix *******************************/
     else if (sum) ii=i;  double **matrix(long nrl, long nrh, long ncl, long nch)
     b[i]=sum;  {
   }    long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
   for (i=n;i>=1;i--) {    double **m;
     sum=b[i];  
     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j];    m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
     b[i]=sum/a[i][i];    if (!m) nrerror("allocation failure 1 in matrix()");
   }    m += NR_END;
 }    m -= nrl;
   
 /************ Frequencies ********************/    m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
 void  freqsummary(char fileres[], int agemin, int agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2,double jprev1, double mprev1,double anprev1,double jprev2, double mprev2,double anprev2)    if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
 {  /* Some frequencies */    m[nrl] += NR_END;
      m[nrl] -= ncl;
   int i, m, jk, k1,i1, j1, bool, z1,z2,j;  
   int first;    for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
   double ***freq; /* Frequencies */    return m;
   double *pp;    /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
   double pos, k2, dateintsum=0,k2cpt=0;  m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
   FILE *ficresp;  that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
   char fileresp[FILENAMELENGTH];     */
    }
   pp=vector(1,nlstate);  
   probs= ma3x(1,AGESUP,1,NCOVMAX, 1,NCOVMAX);  /*************************free matrix ************************/
   strcpy(fileresp,"p");  void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
   strcat(fileresp,fileres);  {
   if((ficresp=fopen(fileresp,"w"))==NULL) {    free((FREE_ARG)(m[nrl]+ncl-NR_END));
     printf("Problem with prevalence resultfile: %s\n", fileresp);    free((FREE_ARG)(m+nrl-NR_END));
     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);  }
     exit(0);  
   }  /******************* ma3x *******************************/
   freq= ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,agemin,agemax+3);  double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
   j1=0;  {
      long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
   j=cptcoveff;    double ***m;
   if (cptcovn<1) {j=1;ncodemax[1]=1;}  
     m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
   first=1;    if (!m) nrerror("allocation failure 1 in matrix()");
     m += NR_END;
   for(k1=1; k1<=j;k1++){    m -= nrl;
     for(i1=1; i1<=ncodemax[k1];i1++){  
       j1++;    m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);    if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
         scanf("%d", i);*/    m[nrl] += NR_END;
       for (i=-1; i<=nlstate+ndeath; i++)      m[nrl] -= ncl;
         for (jk=-1; jk<=nlstate+ndeath; jk++)    
           for(m=agemin; m <= agemax+3; m++)    for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
             freq[i][jk][m]=0;  
          m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
       dateintsum=0;    if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
       k2cpt=0;    m[nrl][ncl] += NR_END;
       for (i=1; i<=imx; i++) {    m[nrl][ncl] -= nll;
         bool=1;    for (j=ncl+1; j<=nch; j++) 
         if  (cptcovn>0) {      m[nrl][j]=m[nrl][j-1]+nlay;
           for (z1=1; z1<=cptcoveff; z1++)    
             if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtab[j1][z1]])    for (i=nrl+1; i<=nrh; i++) {
               bool=0;      m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
         }      for (j=ncl+1; j<=nch; j++) 
         if (bool==1) {        m[i][j]=m[i][j-1]+nlay;
           for(m=firstpass; m<=lastpass; m++){    }
             k2=anint[m][i]+(mint[m][i]/12.);    return m; 
             if ((k2>=dateprev1) && (k2<=dateprev2)) {    /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
               if(agev[m][i]==0) agev[m][i]=agemax+1;             &(m[i][j][k]) <=> *((*(m+i) + j)+k)
               if(agev[m][i]==1) agev[m][i]=agemax+2;    */
               if (m<lastpass) {  }
                 freq[s[m][i]][s[m+1][i]][(int)agev[m][i]] += weight[i];  
                 freq[s[m][i]][s[m+1][i]][(int) agemax+3] += weight[i];  /*************************free ma3x ************************/
               }  void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                {
               if ((agev[m][i]>1) && (agev[m][i]< (agemax+3))) {    free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                 dateintsum=dateintsum+k2;    free((FREE_ARG)(m[nrl]+ncl-NR_END));
                 k2cpt++;    free((FREE_ARG)(m+nrl-NR_END));
               }  }
             }  
           }  /*************** function subdirf ***********/
         }  char *subdirf(char fileres[])
       }  {
            /* Caution optionfilefiname is hidden */
       fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);    strcpy(tmpout,optionfilefiname);
     strcat(tmpout,"/"); /* Add to the right */
       if  (cptcovn>0) {    strcat(tmpout,fileres);
         fprintf(ficresp, "\n#********** Variable ");    return tmpout;
         for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);  }
         fprintf(ficresp, "**********\n#");  
       }  /*************** function subdirf2 ***********/
       for(i=1; i<=nlstate;i++)  char *subdirf2(char fileres[], char *preop)
         fprintf(ficresp, " Age Prev(%d) N(%d) N",i,i);  {
       fprintf(ficresp, "\n");    
          /* Caution optionfilefiname is hidden */
       for(i=(int)agemin; i <= (int)agemax+3; i++){    strcpy(tmpout,optionfilefiname);
         if(i==(int)agemax+3){    strcat(tmpout,"/");
           fprintf(ficlog,"Total");    strcat(tmpout,preop);
         }else{    strcat(tmpout,fileres);
           if(first==1){    return tmpout;
             first=0;  }
             printf("See log file for details...\n");  
           }  /*************** function subdirf3 ***********/
           fprintf(ficlog,"Age %d", i);  char *subdirf3(char fileres[], char *preop, char *preop2)
         }  {
         for(jk=1; jk <=nlstate ; jk++){    
           for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)    /* Caution optionfilefiname is hidden */
             pp[jk] += freq[jk][m][i];    strcpy(tmpout,optionfilefiname);
         }    strcat(tmpout,"/");
         for(jk=1; jk <=nlstate ; jk++){    strcat(tmpout,preop);
           for(m=-1, pos=0; m <=0 ; m++)    strcat(tmpout,preop2);
             pos += freq[jk][m][i];    strcat(tmpout,fileres);
           if(pp[jk]>=1.e-10){    return tmpout;
             if(first==1){  }
             printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);  
             }  char *asc_diff_time(long time_sec, char ascdiff[])
             fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);  {
           }else{    long sec_left, days, hours, minutes;
             if(first==1)    days = (time_sec) / (60*60*24);
               printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);    sec_left = (time_sec) % (60*60*24);
             fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);    hours = (sec_left) / (60*60) ;
           }    sec_left = (sec_left) %(60*60);
         }    minutes = (sec_left) /60;
     sec_left = (sec_left) % (60);
         for(jk=1; jk <=nlstate ; jk++){    sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
           for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)    return ascdiff;
             pp[jk] += freq[jk][m][i];  }
         }  
   /***************** f1dim *************************/
         for(jk=1,pos=0; jk <=nlstate ; jk++)  extern int ncom; 
           pos += pp[jk];  extern double *pcom,*xicom;
         for(jk=1; jk <=nlstate ; jk++){  extern double (*nrfunc)(double []); 
           if(pos>=1.e-5){   
             if(first==1)  double f1dim(double x) 
               printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);  { 
             fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);    int j; 
           }else{    double f;
             if(first==1)    double *xt; 
               printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);   
             fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);    xt=vector(1,ncom); 
           }    for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
           if( i <= (int) agemax){    f=(*nrfunc)(xt); 
             if(pos>=1.e-5){    free_vector(xt,1,ncom); 
               fprintf(ficresp," %d %.5f %.0f %.0f",i,pp[jk]/pos, pp[jk],pos);    return f; 
               probs[i][jk][j1]= pp[jk]/pos;  } 
               /*printf("\ni=%d jk=%d j1=%d %.5f %.0f %.0f %f",i,jk,j1,pp[jk]/pos, pp[jk],pos,probs[i][jk][j1]);*/  
             }  /*****************brent *************************/
             else  double brent(double ax, double bx, double cx, double (*f)(double), double tol,  double *xmin) 
               fprintf(ficresp," %d NaNq %.0f %.0f",i,pp[jk],pos);  {
           }    /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
         }     * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
             * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
         for(jk=-1; jk <=nlstate+ndeath; jk++)     * the minimum is returned as xmin, and the minimum function value is returned as brent , the
           for(m=-1; m <=nlstate+ndeath; m++)     * returned function value. 
             if(freq[jk][m][i] !=0 ) {    */
             if(first==1)    int iter; 
               printf(" %d%d=%.0f",jk,m,freq[jk][m][i]);    double a,b,d,etemp;
               fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][i]);    double fu=0,fv,fw,fx;
             }    double ftemp=0.;
         if(i <= (int) agemax)    double p,q,r,tol1,tol2,u,v,w,x,xm; 
           fprintf(ficresp,"\n");    double e=0.0; 
         if(first==1)   
           printf("Others in log...\n");    a=(ax < cx ? ax : cx); 
         fprintf(ficlog,"\n");    b=(ax > cx ? ax : cx); 
       }    x=w=v=bx; 
     }    fw=fv=fx=(*f)(x); 
   }    for (iter=1;iter<=ITMAX;iter++) { 
   dateintmean=dateintsum/k2cpt;      xm=0.5*(a+b); 
        tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
   fclose(ficresp);      /*          if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
   free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath,(int) agemin,(int) agemax+3);      printf(".");fflush(stdout);
   free_vector(pp,1,nlstate);      fprintf(ficlog,".");fflush(ficlog);
    #ifdef DEBUGBRENT
   /* End of Freq */      printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
 }      fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
       /*          if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
 /************ Prevalence ********************/  #endif
 void prevalence(int agemin, float agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, double calagedate)      if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
 {  /* Some frequencies */        *xmin=x; 
          return fx; 
   int i, m, jk, k1, i1, j1, bool, z1,z2,j;      } 
   double ***freq; /* Frequencies */      ftemp=fu;
   double *pp;      if (fabs(e) > tol1) { 
   double pos, k2;        r=(x-w)*(fx-fv); 
         q=(x-v)*(fx-fw); 
   pp=vector(1,nlstate);        p=(x-v)*q-(x-w)*r; 
   probs= ma3x(1,AGESUP,1,NCOVMAX, 1,NCOVMAX);        q=2.0*(q-r); 
          if (q > 0.0) p = -p; 
   freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,agemin,agemax+3);        q=fabs(q); 
   j1=0;        etemp=e; 
          e=d; 
   j=cptcoveff;        if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
   if (cptcovn<1) {j=1;ncodemax[1]=1;}          d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
          else { 
   for(k1=1; k1<=j;k1++){          d=p/q; 
     for(i1=1; i1<=ncodemax[k1];i1++){          u=x+d; 
       j1++;          if (u-a < tol2 || b-u < tol2) 
                  d=SIGN(tol1,xm-x); 
       for (i=-1; i<=nlstate+ndeath; i++)          } 
         for (jk=-1; jk<=nlstate+ndeath; jk++)        } else { 
           for(m=agemin; m <= agemax+3; m++)        d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
             freq[i][jk][m]=0;      } 
            u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
       for (i=1; i<=imx; i++) {      fu=(*f)(u); 
         bool=1;      if (fu <= fx) { 
         if  (cptcovn>0) {        if (u >= x) a=x; else b=x; 
           for (z1=1; z1<=cptcoveff; z1++)        SHFT(v,w,x,u) 
             if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtab[j1][z1]])        SHFT(fv,fw,fx,fu) 
               bool=0;      } else { 
         }        if (u < x) a=u; else b=u; 
         if (bool==1) {        if (fu <= fw || w == x) { 
           for(m=firstpass; m<=lastpass; m++){          v=w; 
             k2=anint[m][i]+(mint[m][i]/12.);          w=u; 
             if ((k2>=dateprev1) && (k2<=dateprev2)) {          fv=fw; 
               if(agev[m][i]==0) agev[m][i]=agemax+1;          fw=fu; 
               if(agev[m][i]==1) agev[m][i]=agemax+2;        } else if (fu <= fv || v == x || v == w) { 
               if (m<lastpass) {          v=u; 
                 if (calagedate>0)          fv=fu; 
                   freq[s[m][i]][s[m+1][i]][(int)(agev[m][i]+1-((int)calagedate %12)/12.)] += weight[i];        } 
                 else      } 
                   freq[s[m][i]][s[m+1][i]][(int)agev[m][i]] += weight[i];    } 
                 freq[s[m][i]][s[m+1][i]][(int)(agemax+3)] += weight[i];    nrerror("Too many iterations in brent"); 
               }    *xmin=x; 
             }    return fx; 
           }  } 
         }  
       }  /****************** mnbrak ***********************/
       for(i=(int)agemin; i <= (int)agemax+3; i++){  
         for(jk=1; jk <=nlstate ; jk++){  void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
           for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)              double (*func)(double)) 
             pp[jk] += freq[jk][m][i];  { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
         }  the downhill direction (defined by the function as evaluated at the initial points) and returns
         for(jk=1; jk <=nlstate ; jk++){  new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
           for(m=-1, pos=0; m <=0 ; m++)  values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
             pos += freq[jk][m][i];     */
         }    double ulim,u,r,q, dum;
            double fu; 
         for(jk=1; jk <=nlstate ; jk++){  
           for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)    double scale=10.;
             pp[jk] += freq[jk][m][i];    int iterscale=0;
         }  
            *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
         for(jk=1,pos=0; jk <=nlstate ; jk++) pos += pp[jk];    *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
          
         for(jk=1; jk <=nlstate ; jk++){      
           if( i <= (int) agemax){    /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
             if(pos>=1.e-5){    /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
               probs[i][jk][j1]= pp[jk]/pos;    /*   *bx = *ax - (*ax - *bx)/scale; */
             }    /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
           }    /* } */
         }/* end jk */  
       }/* end i */    if (*fb > *fa) { 
     } /* end i1 */      SHFT(dum,*ax,*bx,dum) 
   } /* end k1 */      SHFT(dum,*fb,*fa,dum) 
     } 
      *cx=(*bx)+GOLD*(*bx-*ax); 
   free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath,(int) agemin,(int) agemax+3);    *fc=(*func)(*cx); 
   free_vector(pp,1,nlstate);  #ifdef DEBUG
      printf("mnbrak0 *fb=%.12e *fc=%.12e\n",*fb,*fc);
 }  /* End of Freq */    fprintf(ficlog,"mnbrak0 *fb=%.12e *fc=%.12e\n",*fb,*fc);
   #endif
 /************* Waves Concatenation ***************/    while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc */
       r=(*bx-*ax)*(*fb-*fc); 
 void  concatwav(int wav[], int **dh, int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)      q=(*bx-*cx)*(*fb-*fa); 
 {      u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.        (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
      Death is a valid wave (if date is known).      ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i      if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
      dh[m][i] of dh[mw[mi][i][i] is the delay between two effective waves m=mw[mi][i]        fu=(*func)(u); 
      and mw[mi+1][i]. dh depends on stepm.  #ifdef DEBUG
      */        /* f(x)=A(x-u)**2+f(u) */
         double A, fparabu; 
   int i, mi, m;        A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;        fparabu= *fa - A*(*ax-u)*(*ax-u);
      double sum=0., jmean=0.;*/        printf("mnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu);
   int first;        fprintf(ficlog, "mnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu);
   int j, k=0,jk, ju, jl;        /* And thus,it can be that fu > *fc even if fparabu < *fc */
   double sum=0.;        /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
   first=0;          (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
   jmin=1e+5;        /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
   jmax=-1;  #endif 
   jmean=0.;  #ifdef MNBRAKORIGINAL
   for(i=1; i<=imx; i++){  #else
     mi=0;  /*       if (fu > *fc) { */
     m=firstpass;  /* #ifdef DEBUG */
     while(s[m][i] <= nlstate){  /*       printf("mnbrak4  fu > fc \n"); */
       if(s[m][i]>=1)  /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
         mw[++mi][i]=m;  /* #endif */
       if(m >=lastpass)  /*      /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
         break;  /*      /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
       else  /*      dum=u; /\* Shifting c and u *\/ */
         m++;  /*      u = *cx; */
     }/* end while */  /*      *cx = dum; */
     if (s[m][i] > nlstate){  /*      dum = fu; */
       mi++;     /* Death is another wave */  /*      fu = *fc; */
       /* if(mi==0)  never been interviewed correctly before death */  /*      *fc =dum; */
          /* Only death is a correct wave */  /*       } else { /\* end *\/ */
       mw[mi][i]=m;  /* #ifdef DEBUG */
     }  /*       printf("mnbrak3  fu < fc \n"); */
   /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
     wav[i]=mi;  /* #endif */
     if(mi==0){  /*      dum=u; /\* Shifting c and u *\/ */
       if(first==0){  /*      u = *cx; */
         printf("Warning, no any valid information for:%d line=%d and may be others, see log file\n",num[i],i);  /*      *cx = dum; */
         first=1;  /*      dum = fu; */
       }  /*      fu = *fc; */
       if(first==1){  /*      *fc =dum; */
         fprintf(ficlog,"Warning, no any valid information for:%d line=%d\n",num[i],i);  /*       } */
       }  #ifdef DEBUG
     } /* end mi==0 */        printf("mnbrak34  fu < or >= fc \n");
   }        fprintf(ficlog, "mnbrak34 fu < fc\n");
   #endif
   for(i=1; i<=imx; i++){        dum=u; /* Shifting c and u */
     for(mi=1; mi<wav[i];mi++){        u = *cx;
       if (stepm <=0)        *cx = dum;
         dh[mi][i]=1;        dum = fu;
       else{        fu = *fc;
         if (s[mw[mi+1][i]][i] > nlstate) {        *fc =dum;
           if (agedc[i] < 2*AGESUP) {  #endif
           j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12);      } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
           if(j==0) j=1;  /* Survives at least one month after exam */  #ifdef DEBUG
           k=k+1;        printf("mnbrak2  u after c but before ulim\n");
           if (j >= jmax) jmax=j;        fprintf(ficlog, "mnbrak2 u after c but before ulim\n");
           if (j <= jmin) jmin=j;  #endif
           sum=sum+j;        fu=(*func)(u); 
           /*if (j<0) printf("j=%d num=%d \n",j,i); */        if (fu < *fc) { 
           }  #ifdef DEBUG
         }        printf("mnbrak2  u after c but before ulim AND fu < fc\n");
         else{        fprintf(ficlog, "mnbrak2 u after c but before ulim AND fu <fc \n");
           j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));  #endif
           k=k+1;          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
           if (j >= jmax) jmax=j;          SHFT(*fb,*fc,fu,(*func)(u)) 
           else if (j <= jmin)jmin=j;        } 
           /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */      } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
           sum=sum+j;  #ifdef DEBUG
         }        printf("mnbrak2  u outside ulim (verifying that ulim is beyond c)\n");
         jk= j/stepm;        fprintf(ficlog, "mnbrak2 u outside ulim (verifying that ulim is beyond c)\n");
         jl= j -jk*stepm;  #endif
         ju= j -(jk+1)*stepm;        u=ulim; 
         if(jl <= -ju)        fu=(*func)(u); 
           dh[mi][i]=jk;      } else { /* u could be left to b (if r > q parabola has a maximum) */
         else  #ifdef DEBUG
           dh[mi][i]=jk+1;        printf("mnbrak2  u could be left to b (if r > q parabola has a maximum)\n");
         if(dh[mi][i]==0)        fprintf(ficlog, "mnbrak2  u could be left to b (if r > q parabola has a maximum)\n");
           dh[mi][i]=1; /* At least one step */  #endif
       }        u=(*cx)+GOLD*(*cx-*bx); 
     }        fu=(*func)(u); 
   }      } /* end tests */
   jmean=sum/k;      SHFT(*ax,*bx,*cx,u) 
   printf("Delay (in months) between two waves Min=%d Max=%d Mean=%f\n\n ",jmin, jmax,jmean);      SHFT(*fa,*fb,*fc,fu) 
   fprintf(ficlog,"Delay (in months) between two waves Min=%d Max=%d Mean=%f\n\n ",jmin, jmax,jmean);  #ifdef DEBUG
  }        printf("mnbrak2 (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu);
         fprintf(ficlog, "mnbrak2 (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu);
 /*********** Tricode ****************************/  #endif
 void tricode(int *Tvar, int **nbcode, int imx)    } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
 {  } 
   int Ndum[20],ij=1, k, j, i;  
   int cptcode=0;  /*************** linmin ************************/
   cptcoveff=0;  /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
    resets p to where the function func(p) takes on a minimum along the direction xi from p ,
   for (k=0; k<19; k++) Ndum[k]=0;  and replaces xi by the actual vector displacement that p was moved. Also returns as fret
   for (k=1; k<=7; k++) ncodemax[k]=0;  the value of func at the returned location p . This is actually all accomplished by calling the
   routines mnbrak and brent .*/
   for (j=1; j<=(cptcovn+2*cptcovprod); j++) {  int ncom; 
     for (i=1; i<=imx; i++) {  double *pcom,*xicom;
       ij=(int)(covar[Tvar[j]][i]);  double (*nrfunc)(double []); 
       Ndum[ij]++;   
       /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/  void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
       if (ij > cptcode) cptcode=ij;  { 
     }    double brent(double ax, double bx, double cx, 
                  double (*f)(double), double tol, double *xmin); 
     for (i=0; i<=cptcode; i++) {    double f1dim(double x); 
       if(Ndum[i]!=0) ncodemax[j]++;    void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
     }                double *fc, double (*func)(double)); 
     ij=1;    int j; 
     double xx,xmin,bx,ax; 
     double fx,fb,fa;
     for (i=1; i<=ncodemax[j]; i++) {  
       for (k=0; k<=19; k++) {    double scale=10., axs, xxs, xxss; /* Scale added for infinity */
         if (Ndum[k] != 0) {   
           nbcode[Tvar[j]][ij]=k;    ncom=n; 
              pcom=vector(1,n); 
           ij++;    xicom=vector(1,n); 
         }    nrfunc=func; 
         if (ij > ncodemax[j]) break;    for (j=1;j<=n;j++) { 
       }        pcom[j]=p[j]; 
     }      xicom[j]=xi[j]; 
   }      } 
   
  for (k=0; k<19; k++) Ndum[k]=0;    /* axs=0.0; */
     /* xxss=1; /\* 1 and using scale *\/ */
  for (i=1; i<=ncovmodel-2; i++) {    xxs=1;
    ij=Tvar[i];    /* do{ */
    Ndum[ij]++;      ax=0.;
  }      xx= xxs;
       mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
  ij=1;      /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
  for (i=1; i<=10; i++) {      /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
    if((Ndum[i]!=0) && (i<=ncovcol)){      /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
      Tvaraff[ij]=i;      /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
      ij++;      /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
    }      /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
  }    /*   if (fx != fx){ */
      /*    xxs=xxs/scale; /\* Trying a smaller xx, closer to initial ax=0 *\/ */
  cptcoveff=ij-1;    /*    printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx); */
 }    /*   } */
     /* }while(fx != fx); */
 /*********** Health Expectancies ****************/  
   #ifdef DEBUGLINMIN
 void evsij(char fileres[], double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int ij, int estepm,double delti[],double **matcov )    printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
   #endif
 {    *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
   /* Health expectancies */    /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
   int i, j, nhstepm, hstepm, h, nstepm, k, cptj;    /* fmin = f(p[j] + xmin * xi[j]) */
   double age, agelim, hf;    /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
   double ***p3mat,***varhe;    /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
   double **dnewm,**doldm;  #ifdef DEBUG
   double *xp;    printf("retour brent fret=%.12e xmin=%.12e\n",*fret,xmin);
   double **gp, **gm;    fprintf(ficlog,"retour brent fret=%.12e xmin=%.12e\n",*fret,xmin);
   double ***gradg, ***trgradg;  #endif
   int theta;  #ifdef DEBUGLINMIN
     printf("linmin end ");
   varhe=ma3x(1,nlstate*2,1,nlstate*2,(int) bage, (int) fage);  #endif
   xp=vector(1,npar);    for (j=1;j<=n;j++) { 
   dnewm=matrix(1,nlstate*2,1,npar);      /* printf(" before xi[%d]=%12.8f", j,xi[j]); */
   doldm=matrix(1,nlstate*2,1,nlstate*2);      xi[j] *= xmin; /* xi rescaled by xmin: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
        /* if(xxs <1.0) */
   fprintf(ficreseij,"# Health expectancies\n");      /*   printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs ); */
   fprintf(ficreseij,"# Age");      p[j] += xi[j]; /* Parameters values are updated accordingly */
   for(i=1; i<=nlstate;i++)    } 
     for(j=1; j<=nlstate;j++)    /* printf("\n"); */
       fprintf(ficreseij," %1d-%1d (SE)",i,j);  #ifdef DEBUGLINMIN
   fprintf(ficreseij,"\n");    printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
     for (j=1;j<=n;j++) { 
   if(estepm < stepm){      printf(" xi[%d]= %12.7f p[%d]= %12.7f",j,xi[j],j,p[j]);
     printf ("Problem %d lower than %d\n",estepm, stepm);      if(j % ncovmodel == 0)
   }        printf("\n");
   else  hstepm=estepm;      }
   /* We compute the life expectancy from trapezoids spaced every estepm months  #endif
    * This is mainly to measure the difference between two models: for example    free_vector(xicom,1,n); 
    * if stepm=24 months pijx are given only every 2 years and by summing them    free_vector(pcom,1,n); 
    * we are calculating an estimate of the Life Expectancy assuming a linear  } 
    * progression inbetween and thus overestimating or underestimating according  
    * to the curvature of the survival function. If, for the same date, we  
    * estimate the model with stepm=1 month, we can keep estepm to 24 months  /*************** powell ************************/
    * to compare the new estimate of Life expectancy with the same linear  /*
    * hypothesis. A more precise result, taking into account a more precise  Minimization of a function func of n variables. Input consists of an initial starting point
    * curvature will be obtained if estepm is as small as stepm. */  p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
   rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
   /* For example we decided to compute the life expectancy with the smallest unit */  such that failure to decrease by more than this amount on one iteration signals doneness. On
   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm.  output, p is set to the best point found, xi is the then-current direction set, fret is the returned
      nhstepm is the number of hstepm from age to agelim  function value at p , and iter is the number of iterations taken. The routine linmin is used.
      nstepm is the number of stepm from age to agelin.   */
      Look at hpijx to understand the reason of that which relies in memory size  void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
      and note for a fixed period like estepm months */              double (*func)(double [])) 
   /* We decided (b) to get a life expectancy respecting the most precise curvature of the  { 
      survival function given by stepm (the optimization length). Unfortunately it    void linmin(double p[], double xi[], int n, double *fret, 
      means that if the survival funtion is printed only each two years of age and if                double (*func)(double [])); 
      you sum them up and add 1 year (area under the trapezoids) you won't get the same    int i,ibig,j; 
      results. So we changed our mind and took the option of the best precision.    double del,t,*pt,*ptt,*xit;
   */    double directest;
   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */    double fp,fptt;
     double *xits;
   agelim=AGESUP;    int niterf, itmp;
   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */  
     /* nhstepm age range expressed in number of stepm */    pt=vector(1,n); 
     nstepm=(int) rint((agelim-age)*YEARM/stepm);    ptt=vector(1,n); 
     /* Typically if 20 years nstepm = 20*12/6=40 stepm */    xit=vector(1,n); 
     /* if (stepm >= YEARM) hstepm=1;*/    xits=vector(1,n); 
     nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */    *fret=(*func)(p); 
     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);    for (j=1;j<=n;j++) pt[j]=p[j]; 
     gradg=ma3x(0,nhstepm,1,npar,1,nlstate*2);      rcurr_time = time(NULL);  
     gp=matrix(0,nhstepm,1,nlstate*2);    for (*iter=1;;++(*iter)) { 
     gm=matrix(0,nhstepm,1,nlstate*2);      fp=(*fret); /* From former iteration or initial value */
       ibig=0; 
     /* Computed by stepm unit matrices, product of hstepm matrices, stored      del=0.0; 
        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */      rlast_time=rcurr_time;
     hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, ij);        /* (void) gettimeofday(&curr_time,&tzp); */
        rcurr_time = time(NULL);  
       curr_time = *localtime(&rcurr_time);
     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */      printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
       fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
     /* Computing Variances of health expectancies */  /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
       for (i=1;i<=n;i++) {
      for(theta=1; theta <=npar; theta++){        printf(" %d %.12f",i, p[i]);
       for(i=1; i<=npar; i++){        fprintf(ficlog," %d %.12lf",i, p[i]);
         xp[i] = x[i] + (i==theta ?delti[theta]:0);        fprintf(ficrespow," %.12lf", p[i]);
       }      }
       hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);        printf("\n");
        fprintf(ficlog,"\n");
       cptj=0;      fprintf(ficrespow,"\n");fflush(ficrespow);
       for(j=1; j<= nlstate; j++){      if(*iter <=3){
         for(i=1; i<=nlstate; i++){        tml = *localtime(&rcurr_time);
           cptj=cptj+1;        strcpy(strcurr,asctime(&tml));
           for(h=0, gp[h][cptj]=0.; h<=nhstepm-1; h++){        rforecast_time=rcurr_time; 
             gp[h][cptj] = (p3mat[i][j][h]+p3mat[i][j][h+1])/2.;        itmp = strlen(strcurr);
           }        if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
         }          strcurr[itmp-1]='\0';
       }        printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
              fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
              for(niterf=10;niterf<=30;niterf+=10){
       for(i=1; i<=npar; i++)          rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
         xp[i] = x[i] - (i==theta ?delti[theta]:0);          forecast_time = *localtime(&rforecast_time);
       hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);            strcpy(strfor,asctime(&forecast_time));
                itmp = strlen(strfor);
       cptj=0;          if(strfor[itmp-1]=='\n')
       for(j=1; j<= nlstate; j++){          strfor[itmp-1]='\0';
         for(i=1;i<=nlstate;i++){          printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
           cptj=cptj+1;          fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
           for(h=0, gm[h][cptj]=0.; h<=nhstepm-1; h++){        }
             gm[h][cptj] = (p3mat[i][j][h]+p3mat[i][j][h+1])/2.;      }
           }      for (i=1;i<=n;i++) { /* For each direction i */
         }        for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
       }        fptt=(*fret); 
       for(j=1; j<= nlstate*2; j++)  #ifdef DEBUG
         for(h=0; h<=nhstepm-1; h++){            printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];            fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
         }  #endif
      }            printf("%d",i);fflush(stdout); /* print direction (parameter) i */
            fprintf(ficlog,"%d",i);fflush(ficlog);
 /* End theta */        linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                                       /* Outputs are fret(new point p) p is updated and xit rescaled */
      trgradg =ma3x(0,nhstepm,1,nlstate*2,1,npar);        if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
           /* because that direction will be replaced unless the gain del is small */
      for(h=0; h<=nhstepm-1; h++)          /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
       for(j=1; j<=nlstate*2;j++)          /* Unless the n directions are conjugate some gain in the determinant may be obtained */
         for(theta=1; theta <=npar; theta++)          /* with the new direction. */
           trgradg[h][j][theta]=gradg[h][theta][j];          del=fabs(fptt-(*fret)); 
                ibig=i; 
         } 
      for(i=1;i<=nlstate*2;i++)  #ifdef DEBUG
       for(j=1;j<=nlstate*2;j++)        printf("%d %.12e",i,(*fret));
         varhe[i][j][(int)age] =0.;        fprintf(ficlog,"%d %.12e",i,(*fret));
         for (j=1;j<=n;j++) {
      printf("%d|",(int)age);fflush(stdout);          xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
      fprintf(ficlog,"%d|",(int)age);fflush(ficlog);          printf(" x(%d)=%.12e",j,xit[j]);
      for(h=0;h<=nhstepm-1;h++){          fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
       for(k=0;k<=nhstepm-1;k++){        }
         matprod2(dnewm,trgradg[h],1,nlstate*2,1,npar,1,npar,matcov);        for(j=1;j<=n;j++) {
         matprod2(doldm,dnewm,1,nlstate*2,1,npar,1,nlstate*2,gradg[k]);          printf(" p(%d)=%.12e",j,p[j]);
         for(i=1;i<=nlstate*2;i++)          fprintf(ficlog," p(%d)=%.12e",j,p[j]);
           for(j=1;j<=nlstate*2;j++)        }
             varhe[i][j][(int)age] += doldm[i][j]*hf*hf;        printf("\n");
       }        fprintf(ficlog,"\n");
     }  #endif
     /* Computing expectancies */      } /* end loop on each direction i */
     for(i=1; i<=nlstate;i++)      /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
       for(j=1; j<=nlstate;j++)      /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
         for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){      /* New value of last point Pn is not computed, P(n-1) */
           eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;      if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /* Did we reach enough precision? */
                  /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
 /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/        /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
         /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
         }        /* decreased of more than 3.84  */
         /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
     fprintf(ficreseij,"%3.0f",age );        /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
     cptj=0;        /* By adding 10 parameters more the gain should be 18.31 */
     for(i=1; i<=nlstate;i++)  
       for(j=1; j<=nlstate;j++){        /* Starting the program with initial values given by a former maximization will simply change */
         cptj++;        /* the scales of the directions and the directions, because the are reset to canonical directions */
         fprintf(ficreseij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[cptj][cptj][(int)age]) );        /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
       }        /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
     fprintf(ficreseij,"\n");  #ifdef DEBUG
            int k[2],l;
     free_matrix(gm,0,nhstepm,1,nlstate*2);        k[0]=1;
     free_matrix(gp,0,nhstepm,1,nlstate*2);        k[1]=-1;
     free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*2);        printf("Max: %.12e",(*func)(p));
     free_ma3x(trgradg,0,nhstepm,1,nlstate*2,1,npar);        fprintf(ficlog,"Max: %.12e",(*func)(p));
     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);        for (j=1;j<=n;j++) {
   }          printf(" %.12e",p[j]);
   printf("\n");          fprintf(ficlog," %.12e",p[j]);
   fprintf(ficlog,"\n");        }
         printf("\n");
   free_vector(xp,1,npar);        fprintf(ficlog,"\n");
   free_matrix(dnewm,1,nlstate*2,1,npar);        for(l=0;l<=1;l++) {
   free_matrix(doldm,1,nlstate*2,1,nlstate*2);          for (j=1;j<=n;j++) {
   free_ma3x(varhe,1,nlstate*2,1,nlstate*2,(int) bage, (int)fage);            ptt[j]=p[j]+(p[j]-pt[j])*k[l];
 }            printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
             fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
 /************ Variance ******************/          }
 void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij, int estepm, int cptcov, int cptcod, int popbased)          printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
 {          fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
   /* Variance of health expectancies */        }
   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/  #endif
   /* double **newm;*/  
   double **dnewm,**doldm;  
   double **dnewmp,**doldmp;        free_vector(xit,1,n); 
   int i, j, nhstepm, hstepm, h, nstepm ;        free_vector(xits,1,n); 
   int k, cptcode;        free_vector(ptt,1,n); 
   double *xp;        free_vector(pt,1,n); 
   double **gp, **gm;  /* for var eij */        return; 
   double ***gradg, ***trgradg; /*for var eij */      } /* enough precision */ 
   double **gradgp, **trgradgp; /* for var p point j */      if (*iter == ITMAX) nrerror("powell exceeding maximum iterations."); 
   double *gpp, *gmp; /* for var p point j */      for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
   double **varppt; /* for var p point j nlstate to nlstate+ndeath */        ptt[j]=2.0*p[j]-pt[j]; 
   double ***p3mat;        xit[j]=p[j]-pt[j]; 
   double age,agelim, hf;        pt[j]=p[j]; 
   int theta;      } 
   char digit[4];      fptt=(*func)(ptt); /* f_3 */
   char digitp[16];  #ifdef POWELLF1F3
   #else
   char fileresprobmorprev[FILENAMELENGTH];      if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
   #endif
   if(popbased==1)        /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
     strcpy(digitp,"-populbased-");        /* From x1 (P0) distance of x2 is at h and x3 is 2h */
   else        /* Let f"(x2) be the 2nd derivative equal everywhere.  */
     strcpy(digitp,"-stablbased-");        /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
         /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
   strcpy(fileresprobmorprev,"prmorprev");        /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del */
   sprintf(digit,"%-d",ij);        /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
   /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/  #ifdef NRCORIGINAL
   strcat(fileresprobmorprev,digit); /* Tvar to be done */        t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
   strcat(fileresprobmorprev,digitp); /* Popbased or not */  #else
   strcat(fileresprobmorprev,fileres);        t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
   if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {        t= t- del*SQR(fp-fptt);
     printf("Problem with resultfile: %s\n", fileresprobmorprev);  #endif
     fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);        directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If del was big enough we change it for a new direction */
   }  #ifdef DEBUG
   printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);        printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
   fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);        fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
   fprintf(ficresprobmorprev,"# probabilities of dying during a year and weighted mean w1*p1j+w2*p2j+... stand dev in()\n");        printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
   fprintf(ficresprobmorprev,"# Age cov=%-d",ij);               (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
   for(j=nlstate+1; j<=(nlstate+ndeath);j++){        fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
     fprintf(ficresprobmorprev," p.%-d SE",j);               (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
     for(i=1; i<=nlstate;i++)        printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
       fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);        fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
   }    #endif
   fprintf(ficresprobmorprev,"\n");  #ifdef POWELLORIGINAL
   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) {        if (t < 0.0) { /* Then we use it for new direction */
     printf("Problem with gnuplot file: %s\n", optionfilegnuplot);  #else
     fprintf(ficlog,"Problem with gnuplot file: %s\n", optionfilegnuplot);        if (directest*t < 0.0) { /* Contradiction between both tests */
     exit(0);          printf("directest= %.12lf, t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
   }          printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
   else{          fprintf(ficlog,"directest= %.12lf, t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
     fprintf(ficgp,"\n# Routine varevsij");          fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
   }        } 
   if((fichtm=fopen(optionfilehtm,"a"))==NULL) {        if (directest < 0.0) { /* Then we use it for new direction */
     printf("Problem with html file: %s\n", optionfilehtm);  #endif
     fprintf(ficlog,"Problem with html file: %s\n", optionfilehtm);  #ifdef DEBUGLINMIN
     exit(0);          printf("Before linmin in direction P%d-P0\n",n);
   }          for (j=1;j<=n;j++) { 
   else{            printf("Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
     fprintf(fichtm,"\n<li><h4> Computing step probabilities of dying and weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");            if(j % ncovmodel == 0)
   }              printf("\n");
   varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);          }
   #endif
   fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are the stable prevalence in health states i\n");          linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
   fprintf(ficresvij,"# Age");  #ifdef DEBUGLINMIN
   for(i=1; i<=nlstate;i++)          for (j=1;j<=n;j++) { 
     for(j=1; j<=nlstate;j++)            printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
       fprintf(ficresvij," Cov(e%1d, e%1d)",i,j);            if(j % ncovmodel == 0)
   fprintf(ficresvij,"\n");              printf("\n");
           }
   xp=vector(1,npar);  #endif
   dnewm=matrix(1,nlstate,1,npar);          for (j=1;j<=n;j++) { 
   doldm=matrix(1,nlstate,1,nlstate);            xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
   dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);            xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
   doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);          }
           printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
   gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);          fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
   gpp=vector(nlstate+1,nlstate+ndeath);  
   gmp=vector(nlstate+1,nlstate+ndeath);  #ifdef DEBUG
   trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/          printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
            fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
   if(estepm < stepm){          for(j=1;j<=n;j++){
     printf ("Problem %d lower than %d\n",estepm, stepm);            printf(" %.12e",xit[j]);
   }            fprintf(ficlog," %.12e",xit[j]);
   else  hstepm=estepm;            }
   /* For example we decided to compute the life expectancy with the smallest unit */          printf("\n");
   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm.          fprintf(ficlog,"\n");
      nhstepm is the number of hstepm from age to agelim  #endif
      nstepm is the number of stepm from age to agelin.        } /* end of t or directest negative */
      Look at hpijx to understand the reason of that which relies in memory size  #ifdef POWELLF1F3
      and note for a fixed period like k years */  #else
   /* We decided (b) to get a life expectancy respecting the most precise curvature of the      } /* end if (fptt < fp)  */
      survival function given by stepm (the optimization length). Unfortunately it  #endif
      means that if the survival funtion is printed only each two years of age and if    } /* loop iteration */ 
      you sum them up and add 1 year (area under the trapezoids) you won't get the same  } 
      results. So we changed our mind and took the option of the best precision.  
   */  /**** Prevalence limit (stable or period prevalence)  ****************/
   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */  
   agelim = AGESUP;  double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int ij)
   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */  {
     nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */    /* Computes the prevalence limit in each live state at age x by left multiplying the unit
     nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */       matrix by transitions matrix until convergence is reached */
     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);    
     gradg=ma3x(0,nhstepm,1,npar,1,nlstate);    int i, ii,j,k;
     gp=matrix(0,nhstepm,1,nlstate);    double min, max, maxmin, maxmax,sumnew=0.;
     gm=matrix(0,nhstepm,1,nlstate);    /* double **matprod2(); */ /* test */
     double **out, cov[NCOVMAX+1], **pmij();
     double **newm;
     for(theta=1; theta <=npar; theta++){    double agefin, delaymax=50 ; /* Max number of years to converge */
       for(i=1; i<=npar; i++){ /* Computes gradient */    
         xp[i] = x[i] + (i==theta ?delti[theta]:0);    for (ii=1;ii<=nlstate+ndeath;ii++)
       }      for (j=1;j<=nlstate+ndeath;j++){
       hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);      }
     
       if (popbased==1) {    cov[1]=1.;
         for(i=1; i<=nlstate;i++)    
           prlim[i][i]=probs[(int)age][i][ij];    /* Even if hstepm = 1, at least one multiplication by the unit matrix */
       }    for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
        newm=savm;
       for(j=1; j<= nlstate; j++){      /* Covariates have to be included here again */
         for(h=0; h<=nhstepm; h++){      cov[2]=agefin;
           for(i=1, gp[h][j]=0.;i<=nlstate;i++)      if(nagesqr==1)
             gp[h][j] += prlim[i][i]*p3mat[i][j][h];        cov[3]= agefin*agefin;;
         }      for (k=1; k<=cptcovn;k++) {
       }        /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
       /* This for computing forces of mortality (h=1)as a weighted average */        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
       for(j=nlstate+1,gpp[j]=0.;j<=nlstate+ndeath;j++){        /* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); */
         for(i=1; i<= nlstate; i++)      }
           gpp[j] += prlim[i][i]*p3mat[i][j][1];      /*wrong? for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
       }          /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]*cov[2]; */
       /* end force of mortality */      for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2];
       for (k=1; k<=cptcovprod;k++) /* Useless */
       for(i=1; i<=npar; i++) /* Computes gradient */        /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
         xp[i] = x[i] - (i==theta ?delti[theta]:0);        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
       hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);        
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);      /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
        /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
       if (popbased==1) {      /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
         for(i=1; i<=nlstate;i++)      /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
           prlim[i][i]=probs[(int)age][i][ij];      /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
       }      out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
       
       for(j=1; j<= nlstate; j++){      savm=oldm;
         for(h=0; h<=nhstepm; h++){      oldm=newm;
           for(i=1, gm[h][j]=0.;i<=nlstate;i++)      maxmax=0.;
             gm[h][j] += prlim[i][i]*p3mat[i][j][h];      for(j=1;j<=nlstate;j++){
         }        min=1.;
       }        max=0.;
       /* This for computing force of mortality (h=1)as a weighted average */        for(i=1; i<=nlstate; i++) {
       for(j=nlstate+1,gmp[j]=0.;j<=nlstate+ndeath;j++){          sumnew=0;
         for(i=1; i<= nlstate; i++)          for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
           gmp[j] += prlim[i][i]*p3mat[i][j][1];          prlim[i][j]= newm[i][j]/(1-sumnew);
       }              /*printf(" prevalim i=%d, j=%d, prmlim[%d][%d]=%f, agefin=%d \n", i, j, i, j, prlim[i][j],(int)agefin);*/
       /* end force of mortality */          max=FMAX(max,prlim[i][j]);
           min=FMIN(min,prlim[i][j]);
       for(j=1; j<= nlstate; j++) /* vareij */        }
         for(h=0; h<=nhstepm; h++){        maxmin=max-min;
           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];        maxmax=FMAX(maxmax,maxmin);
         }      } /* j loop */
       for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */      if(maxmax < ftolpl){
         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];        return prlim;
       }      }
     } /* age loop */
     } /* End theta */    return prlim; /* should not reach here */
   }
     trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */  
   /*************** transition probabilities ***************/ 
     for(h=0; h<=nhstepm; h++) /* veij */  
       for(j=1; j<=nlstate;j++)  double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
         for(theta=1; theta <=npar; theta++)  {
           trgradg[h][j][theta]=gradg[h][theta][j];    /* According to parameters values stored in x and the covariate's values stored in cov,
        computes the probability to be observed in state j being in state i by appying the
     for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */       model to the ncovmodel covariates (including constant and age).
       for(theta=1; theta <=npar; theta++)       lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
         trgradgp[j][theta]=gradgp[theta][j];       and, according on how parameters are entered, the position of the coefficient xij(nc) of the
        ncth covariate in the global vector x is given by the formula:
     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */       j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
     for(i=1;i<=nlstate;i++)       j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
       for(j=1;j<=nlstate;j++)       Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
         vareij[i][j][(int)age] =0.;       sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
        Outputs ps[i][j] the probability to be observed in j being in j according to
     for(h=0;h<=nhstepm;h++){       the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
       for(k=0;k<=nhstepm;k++){    */
         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);    double s1, lnpijopii;
         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);    /*double t34;*/
         for(i=1;i<=nlstate;i++)    int i,j, nc, ii, jj;
           for(j=1;j<=nlstate;j++)  
             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;      for(i=1; i<= nlstate; i++){
       }        for(j=1; j<i;j++){
     }          for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
             /*lnpijopii += param[i][j][nc]*cov[nc];*/
     /* pptj */            lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
     matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);  /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
     matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);          }
     for(j=nlstate+1;j<=nlstate+ndeath;j++)          ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
       for(i=nlstate+1;i<=nlstate+ndeath;i++)  /*      printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
         varppt[j][i]=doldmp[j][i];        }
     /* end ppptj */        for(j=i+1; j<=nlstate+ndeath;j++){
     hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij);            for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
     prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ij);            /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
              lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
     if (popbased==1) {  /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
       for(i=1; i<=nlstate;i++)          }
         prlim[i][i]=probs[(int)age][i][ij];          ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
     }        }
          }
     /* This for computing force of mortality (h=1)as a weighted average */      
     for(j=nlstate+1,gmp[j]=0.;j<=nlstate+ndeath;j++){      for(i=1; i<= nlstate; i++){
       for(i=1; i<= nlstate; i++)        s1=0;
         gmp[j] += prlim[i][i]*p3mat[i][j][1];        for(j=1; j<i; j++){
     }              s1+=exp(ps[i][j]); /* In fact sums pij/pii */
     /* end force of mortality */          /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
         }
     fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);        for(j=i+1; j<=nlstate+ndeath; j++){
     for(j=nlstate+1; j<=(nlstate+ndeath);j++){          s1+=exp(ps[i][j]); /* In fact sums pij/pii */
       fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));          /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
       for(i=1; i<=nlstate;i++){        }
         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);        /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
       }        ps[i][i]=1./(s1+1.);
     }        /* Computing other pijs */
     fprintf(ficresprobmorprev,"\n");        for(j=1; j<i; j++)
           ps[i][j]= exp(ps[i][j])*ps[i][i];
     fprintf(ficresvij,"%.0f ",age );        for(j=i+1; j<=nlstate+ndeath; j++)
     for(i=1; i<=nlstate;i++)          ps[i][j]= exp(ps[i][j])*ps[i][i];
       for(j=1; j<=nlstate;j++){        /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);      } /* end i */
       }      
     fprintf(ficresvij,"\n");      for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
     free_matrix(gp,0,nhstepm,1,nlstate);        for(jj=1; jj<= nlstate+ndeath; jj++){
     free_matrix(gm,0,nhstepm,1,nlstate);          ps[ii][jj]=0;
     free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);          ps[ii][ii]=1;
     free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);        }
     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);      }
   } /* End age */      
   free_vector(gpp,nlstate+1,nlstate+ndeath);      
   free_vector(gmp,nlstate+1,nlstate+ndeath);      /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
   free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);      /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
   free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/      /*  printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
   fprintf(ficgp,"\nset noparametric;set nolabel; set ter png small;set size 0.65, 0.65");      /*   } */
   /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */      /*   printf("\n "); */
   fprintf(ficgp,"\n set log y; set nolog x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");      /* } */
   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm);      /* printf("\n ");printf("%lf ",cov[2]);*/
   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm);      /*
   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm);        for(i=1; i<= npar; i++) printf("%f ",x[i]);
   fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",fileresprobmorprev,fileresprobmorprev);        goto end;*/
   fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.png\"> <br>\n", stepm,YEARM,digitp,digit);      return ps;
   fprintf(ficgp,"\nset out \"varmuptjgr%s%s.png\";replot;",digitp,digit);  }
   
   free_vector(xp,1,npar);  /**************** Product of 2 matrices ******************/
   free_matrix(doldm,1,nlstate,1,nlstate);  
   free_matrix(dnewm,1,nlstate,1,npar);  double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
   free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);  {
   free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);    /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
   free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);       b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
   fclose(ficresprobmorprev);    /* in, b, out are matrice of pointers which should have been initialized 
   fclose(ficgp);       before: only the contents of out is modified. The function returns
   fclose(fichtm);       a pointer to pointers identical to out */
     int i, j, k;
 }    for(i=nrl; i<= nrh; i++)
       for(k=ncolol; k<=ncoloh; k++){
 /************ Variance of prevlim ******************/        out[i][k]=0.;
 void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij)        for(j=ncl; j<=nch; j++)
 {          out[i][k] +=in[i][j]*b[j][k];
   /* Variance of prevalence limit */      }
   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/    return out;
   double **newm;  }
   double **dnewm,**doldm;  
   int i, j, nhstepm, hstepm;  
   int k, cptcode;  /************* Higher Matrix Product ***************/
   double *xp;  
   double *gp, *gm;  double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij )
   double **gradg, **trgradg;  {
   double age,agelim;    /* Computes the transition matrix starting at age 'age' over 
   int theta;       'nhstepm*hstepm*stepm' months (i.e. until
           age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
   fprintf(ficresvpl,"# Standard deviation of prevalence's limit\n");       nhstepm*hstepm matrices. 
   fprintf(ficresvpl,"# Age");       Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
   for(i=1; i<=nlstate;i++)       (typically every 2 years instead of every month which is too big 
       fprintf(ficresvpl," %1d-%1d",i,i);       for the memory).
   fprintf(ficresvpl,"\n");       Model is determined by parameters x and covariates have to be 
        included manually here. 
   xp=vector(1,npar);  
   dnewm=matrix(1,nlstate,1,npar);       */
   doldm=matrix(1,nlstate,1,nlstate);  
      int i, j, d, h, k;
   hstepm=1*YEARM; /* Every year of age */    double **out, cov[NCOVMAX+1];
   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */    double **newm;
   agelim = AGESUP;    double agexact;
   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */  
     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */    /* Hstepm could be zero and should return the unit matrix */
     if (stepm >= YEARM) hstepm=1;    for (i=1;i<=nlstate+ndeath;i++)
     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */      for (j=1;j<=nlstate+ndeath;j++){
     gradg=matrix(1,npar,1,nlstate);        oldm[i][j]=(i==j ? 1.0 : 0.0);
     gp=vector(1,nlstate);        po[i][j][0]=(i==j ? 1.0 : 0.0);
     gm=vector(1,nlstate);      }
     /* Even if hstepm = 1, at least one multiplication by the unit matrix */
     for(theta=1; theta <=npar; theta++){    for(h=1; h <=nhstepm; h++){
       for(i=1; i<=npar; i++){ /* Computes gradient */      for(d=1; d <=hstepm; d++){
         xp[i] = x[i] + (i==theta ?delti[theta]:0);        newm=savm;
       }        /* Covariates have to be included here again */
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);        cov[1]=1.;
       for(i=1;i<=nlstate;i++)        agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM;
         gp[i] = prlim[i][i];        cov[2]=agexact;
            if(nagesqr==1)
       for(i=1; i<=npar; i++) /* Computes gradient */          cov[3]= agexact*agexact;
         xp[i] = x[i] - (i==theta ?delti[theta]:0);        for (k=1; k<=cptcovn;k++) 
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);          cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
       for(i=1;i<=nlstate;i++)          /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
         gm[i] = prlim[i][i];        for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
           /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
       for(i=1;i<=nlstate;i++)          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
         gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];          /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
     } /* End theta */        for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
           cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
     trgradg =matrix(1,nlstate,1,npar);          /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
   
     for(j=1; j<=nlstate;j++)  
       for(theta=1; theta <=npar; theta++)        /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
         trgradg[j][theta]=gradg[theta][j];        /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
         out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
     for(i=1;i<=nlstate;i++)                     pmij(pmmij,cov,ncovmodel,x,nlstate));
       varpl[i][(int)age] =0.;        savm=oldm;
     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);        oldm=newm;
     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);      }
     for(i=1;i<=nlstate;i++)      for(i=1; i<=nlstate+ndeath; i++)
       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */        for(j=1;j<=nlstate+ndeath;j++) {
           po[i][j][h]=newm[i][j];
     fprintf(ficresvpl,"%.0f ",age );          /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
     for(i=1; i<=nlstate;i++)        }
       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));      /*printf("h=%d ",h);*/
     fprintf(ficresvpl,"\n");    } /* end h */
     free_vector(gp,1,nlstate);  /*     printf("\n H=%d \n",h); */
     free_vector(gm,1,nlstate);    return po;
     free_matrix(gradg,1,npar,1,nlstate);  }
     free_matrix(trgradg,1,nlstate,1,npar);  
   } /* End age */  #ifdef NLOPT
     double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
   free_vector(xp,1,npar);    double fret;
   free_matrix(doldm,1,nlstate,1,npar);    double *xt;
   free_matrix(dnewm,1,nlstate,1,nlstate);    int j;
     myfunc_data *d2 = (myfunc_data *) pd;
 }  /* xt = (p1-1); */
     xt=vector(1,n); 
 /************ Variance of one-step probabilities  ******************/    for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
 void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax)  
 {    fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
   int i, j=0,  i1, k1, l1, t, tj;    /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
   int k2, l2, j1,  z1;    printf("Function = %.12lf ",fret);
   int k=0,l, cptcode;    for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
   int first=1, first1;    printf("\n");
   double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;   free_vector(xt,1,n);
   double **dnewm,**doldm;    return fret;
   double *xp;  }
   double *gp, *gm;  #endif
   double **gradg, **trgradg;  
   double **mu;  /*************** log-likelihood *************/
   double age,agelim, cov[NCOVMAX];  double func( double *x)
   double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */  {
   int theta;    int i, ii, j, k, mi, d, kk;
   char fileresprob[FILENAMELENGTH];    double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
   char fileresprobcov[FILENAMELENGTH];    double **out;
   char fileresprobcor[FILENAMELENGTH];    double sw; /* Sum of weights */
     double lli; /* Individual log likelihood */
   double ***varpij;    int s1, s2;
     double bbh, survp;
   strcpy(fileresprob,"prob");    long ipmx;
   strcat(fileresprob,fileres);    double agexact;
   if((ficresprob=fopen(fileresprob,"w"))==NULL) {    /*extern weight */
     printf("Problem with resultfile: %s\n", fileresprob);    /* We are differentiating ll according to initial status */
     fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);    /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
   }    /*for(i=1;i<imx;i++) 
   strcpy(fileresprobcov,"probcov");      printf(" %d\n",s[4][i]);
   strcat(fileresprobcov,fileres);    */
   if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {  
     printf("Problem with resultfile: %s\n", fileresprobcov);    ++countcallfunc;
     fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);  
   }    cov[1]=1.;
   strcpy(fileresprobcor,"probcor");  
   strcat(fileresprobcor,fileres);    for(k=1; k<=nlstate; k++) ll[k]=0.;
   if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {  
     printf("Problem with resultfile: %s\n", fileresprobcor);    if(mle==1){
     fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
   }        /* Computes the values of the ncovmodel covariates of the model
   printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);           depending if the covariates are fixed or variying (age dependent) and stores them in cov[]
   fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);           Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
   printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);           to be observed in j being in i according to the model.
   fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);         */
   printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);        for (k=1; k<=cptcovn;k++){ /* Simple and product covariates without age* products */
   fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);            cov[2+nagesqr+k]=covar[Tvar[k]][i];
          }
   fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");        /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
   fprintf(ficresprob,"# Age");           is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
   fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");           has been calculated etc */
   fprintf(ficresprobcov,"# Age");        for(mi=1; mi<= wav[i]-1; mi++){
   fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");          for (ii=1;ii<=nlstate+ndeath;ii++)
   fprintf(ficresprobcov,"# Age");            for (j=1;j<=nlstate+ndeath;j++){
               oldm[ii][j]=(ii==j ? 1.0 : 0.0);
               savm[ii][j]=(ii==j ? 1.0 : 0.0);
   for(i=1; i<=nlstate;i++)            }
     for(j=1; j<=(nlstate+ndeath);j++){          for(d=0; d<dh[mi][i]; d++){
       fprintf(ficresprob," p%1d-%1d (SE)",i,j);            newm=savm;
       fprintf(ficresprobcov," p%1d-%1d ",i,j);            agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
       fprintf(ficresprobcor," p%1d-%1d ",i,j);            cov[2]=agexact;
     }              if(nagesqr==1)
   fprintf(ficresprob,"\n");              cov[3]= agexact*agexact;
   fprintf(ficresprobcov,"\n");            for (kk=1; kk<=cptcovage;kk++) {
   fprintf(ficresprobcor,"\n");              cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
   xp=vector(1,npar);            }
   dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
   doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
   mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);            savm=oldm;
   varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);            oldm=newm;
   first=1;          } /* end mult */
   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) {        
     printf("Problem with gnuplot file: %s\n", optionfilegnuplot);          /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
     fprintf(ficlog,"Problem with gnuplot file: %s\n", optionfilegnuplot);          /* But now since version 0.9 we anticipate for bias at large stepm.
     exit(0);           * If stepm is larger than one month (smallest stepm) and if the exact delay 
   }           * (in months) between two waves is not a multiple of stepm, we rounded to 
   else{           * the nearest (and in case of equal distance, to the lowest) interval but now
     fprintf(ficgp,"\n# Routine varprob");           * we keep into memory the bias bh[mi][i] and also the previous matrix product
   }           * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
   if((fichtm=fopen(optionfilehtm,"a"))==NULL) {           * probability in order to take into account the bias as a fraction of the way
     printf("Problem with html file: %s\n", optionfilehtm);           * from savm to out if bh is negative or even beyond if bh is positive. bh varies
     fprintf(ficlog,"Problem with html file: %s\n", optionfilehtm);           * -stepm/2 to stepm/2 .
     exit(0);           * For stepm=1 the results are the same as for previous versions of Imach.
   }           * For stepm > 1 the results are less biased than in previous versions. 
   else{           */
     fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");          s1=s[mw[mi][i]][i];
     fprintf(fichtm,"\n");          s2=s[mw[mi+1][i]][i];
           bbh=(double)bh[mi][i]/(double)stepm; 
     fprintf(fichtm,"\n<li><h4> Computing matrix of variance-covariance of step probabilities</h4></li>\n");          /* bias bh is positive if real duration
     fprintf(fichtm,"\nWe have drawn ellipsoids of confidence around the p<inf>ij</inf>, p<inf>kl</inf> to understand the covariance between two incidences. They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");           * is higher than the multiple of stepm and negative otherwise.
     fprintf(fichtm,"\n<br> We have drawn x'cov<sup>-1</sup>x = 4 where x is the column vector (pij,pkl). It means that if pij and pkl where uncorrelated the (2X2) matrix would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 standard deviations wide on each axis. <br> When both incidences are correlated we diagonalised the inverse of the covariance matrix and made the appropriate rotation.<br> \n");           */
           /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
   }          if( s2 > nlstate){ 
             /* i.e. if s2 is a death state and if the date of death is known 
                 then the contribution to the likelihood is the probability to 
   cov[1]=1;               die between last step unit time and current  step unit time, 
   tj=cptcoveff;               which is also equal to probability to die before dh 
   if (cptcovn<1) {tj=1;ncodemax[1]=1;}               minus probability to die before dh-stepm . 
   j1=0;               In version up to 0.92 likelihood was computed
   for(t=1; t<=tj;t++){          as if date of death was unknown. Death was treated as any other
     for(i1=1; i1<=ncodemax[t];i1++){          health state: the date of the interview describes the actual state
       j1++;          and not the date of a change in health state. The former idea was
                to consider that at each interview the state was recorded
       if  (cptcovn>0) {          (healthy, disable or death) and IMaCh was corrected; but when we
         fprintf(ficresprob, "\n#********** Variable ");          introduced the exact date of death then we should have modified
         for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);          the contribution of an exact death to the likelihood. This new
         fprintf(ficresprob, "**********\n#");          contribution is smaller and very dependent of the step unit
         fprintf(ficresprobcov, "\n#********** Variable ");          stepm. It is no more the probability to die between last interview
         for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);          and month of death but the probability to survive from last
         fprintf(ficresprobcov, "**********\n#");          interview up to one month before death multiplied by the
                  probability to die within a month. Thanks to Chris
         fprintf(ficgp, "\n#********** Variable ");          Jackson for correcting this bug.  Former versions increased
         for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, "# V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);          mortality artificially. The bad side is that we add another loop
         fprintf(ficgp, "**********\n#");          which slows down the processing. The difference can be up to 10%
                  lower mortality.
                    */
         fprintf(fichtm, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable ");          /* If, at the beginning of the maximization mostly, the
         for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);             cumulative probability or probability to be dead is
         fprintf(fichtm, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");             constant (ie = 1) over time d, the difference is equal to
                     0.  out[s1][3] = savm[s1][3]: probability, being at state
         fprintf(ficresprobcor, "\n#********** Variable ");                 s1 at precedent wave, to be dead a month before current
         for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);             wave is equal to probability, being at state s1 at
         fprintf(ficgp, "**********\n#");                 precedent wave, to be dead at mont of the current
       }             wave. Then the observed probability (that this person died)
                   is null according to current estimated parameter. In fact,
       for (age=bage; age<=fage; age ++){             it should be very low but not zero otherwise the log go to
         cov[2]=age;             infinity.
         for (k=1; k<=cptcovn;k++) {          */
           cov[2+k]=nbcode[Tvar[k]][codtab[j1][Tvar[k]]];  /* #ifdef INFINITYORIGINAL */
         }  /*          lli=log(out[s1][s2] - savm[s1][s2]); */
         for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];  /* #else */
         for (k=1; k<=cptcovprod;k++)  /*        if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
           cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];  /*          lli=log(mytinydouble); */
          /*        else */
         gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));  /*          lli=log(out[s1][s2] - savm[s1][s2]); */
         trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);  /* #endif */
         gp=vector(1,(nlstate)*(nlstate+ndeath));              lli=log(out[s1][s2] - savm[s1][s2]);
         gm=vector(1,(nlstate)*(nlstate+ndeath));  
              } else if  (s2==-2) {
         for(theta=1; theta <=npar; theta++){            for (j=1,survp=0. ; j<=nlstate; j++) 
           for(i=1; i<=npar; i++)              survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
             xp[i] = x[i] + (i==theta ?delti[theta]:0);            /*survp += out[s1][j]; */
                      lli= log(survp);
           pmij(pmmij,cov,ncovmodel,xp,nlstate);          }
                    
           k=0;          else if  (s2==-4) { 
           for(i=1; i<= (nlstate); i++){            for (j=3,survp=0. ; j<=nlstate; j++)  
             for(j=1; j<=(nlstate+ndeath);j++){              survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
               k=k+1;            lli= log(survp); 
               gp[k]=pmmij[i][j];          } 
             }  
           }          else if  (s2==-5) { 
                      for (j=1,survp=0. ; j<=2; j++)  
           for(i=1; i<=npar; i++)              survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
             xp[i] = x[i] - (i==theta ?delti[theta]:0);            lli= log(survp); 
              } 
           pmij(pmmij,cov,ncovmodel,xp,nlstate);          
           k=0;          else{
           for(i=1; i<=(nlstate); i++){            lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
             for(j=1; j<=(nlstate+ndeath);j++){            /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
               k=k+1;          } 
               gm[k]=pmmij[i][j];          /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
             }          /*if(lli ==000.0)*/
           }          /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                ipmx +=1;
           for(i=1; i<= (nlstate)*(nlstate+ndeath); i++)          sw += weight[i];
             gradg[theta][i]=(gp[i]-gm[i])/2./delti[theta];            ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
         }          /* if (lli < log(mytinydouble)){ */
           /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
         for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)          /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
           for(theta=1; theta <=npar; theta++)          /* } */
             trgradg[j][theta]=gradg[theta][j];        } /* end of wave */
              } /* end of individual */
         matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov);    }  else if(mle==2){
         matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
         pmij(pmmij,cov,ncovmodel,x,nlstate);        for(mi=1; mi<= wav[i]-1; mi++){
                  for (ii=1;ii<=nlstate+ndeath;ii++)
         k=0;            for (j=1;j<=nlstate+ndeath;j++){
         for(i=1; i<=(nlstate); i++){              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
           for(j=1; j<=(nlstate+ndeath);j++){              savm[ii][j]=(ii==j ? 1.0 : 0.0);
             k=k+1;            }
             mu[k][(int) age]=pmmij[i][j];          for(d=0; d<=dh[mi][i]; d++){
           }            newm=savm;
         }            agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
         for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)            cov[2]=agexact;
           for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)            if(nagesqr==1)
             varpij[i][j][(int)age] = doldm[i][j];              cov[3]= agexact*agexact;
             for (kk=1; kk<=cptcovage;kk++) {
         /*printf("\n%d ",(int)age);              cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
      for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){            }
        printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
        fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
      }*/            savm=oldm;
             oldm=newm;
         fprintf(ficresprob,"\n%d ",(int)age);          } /* end mult */
         fprintf(ficresprobcov,"\n%d ",(int)age);        
         fprintf(ficresprobcor,"\n%d ",(int)age);          s1=s[mw[mi][i]][i];
           s2=s[mw[mi+1][i]][i];
         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)          bbh=(double)bh[mi][i]/(double)stepm; 
           fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));          lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){          ipmx +=1;
           fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);          sw += weight[i];
           fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
         }        } /* end of wave */
         i=0;      } /* end of individual */
         for (k=1; k<=(nlstate);k++){    }  else if(mle==3){  /* exponential inter-extrapolation */
           for (l=1; l<=(nlstate+ndeath);l++){      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
             i=i++;        for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
             fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);        for(mi=1; mi<= wav[i]-1; mi++){
             fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);          for (ii=1;ii<=nlstate+ndeath;ii++)
             for (j=1; j<=i;j++){            for (j=1;j<=nlstate+ndeath;j++){
               fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
               fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));              savm[ii][j]=(ii==j ? 1.0 : 0.0);
             }            }
           }          for(d=0; d<dh[mi][i]; d++){
         }/* end of loop for state */            newm=savm;
       } /* end of loop for age */            agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
             cov[2]=agexact;
       /* Confidence intervalle of pij  */            if(nagesqr==1)
       /*              cov[3]= agexact*agexact;
       fprintf(ficgp,"\nset noparametric;unset label");            for (kk=1; kk<=cptcovage;kk++) {
       fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");              cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
       fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");            }
       fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
       fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
       fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);            savm=oldm;
       fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);            oldm=newm;
       */          } /* end mult */
         
       /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/          s1=s[mw[mi][i]][i];
       first1=1;          s2=s[mw[mi+1][i]][i];
       for (k2=1; k2<=(nlstate);k2++){          bbh=(double)bh[mi][i]/(double)stepm; 
         for (l2=1; l2<=(nlstate+ndeath);l2++){          lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
           if(l2==k2) continue;          ipmx +=1;
           j=(k2-1)*(nlstate+ndeath)+l2;          sw += weight[i];
           for (k1=1; k1<=(nlstate);k1++){          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
             for (l1=1; l1<=(nlstate+ndeath);l1++){        } /* end of wave */
               if(l1==k1) continue;      } /* end of individual */
               i=(k1-1)*(nlstate+ndeath)+l1;    }else if (mle==4){  /* ml=4 no inter-extrapolation */
               if(i<=j) continue;      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
               for (age=bage; age<=fage; age ++){        for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                 if ((int)age %5==0){        for(mi=1; mi<= wav[i]-1; mi++){
                   v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;          for (ii=1;ii<=nlstate+ndeath;ii++)
                   v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;            for (j=1;j<=nlstate+ndeath;j++){
                   cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   mu1=mu[i][(int) age]/stepm*YEARM ;              savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   mu2=mu[j][(int) age]/stepm*YEARM;            }
                   c12=cv12/sqrt(v1*v2);          for(d=0; d<dh[mi][i]; d++){
                   /* Computing eigen value of matrix of covariance */            newm=savm;
                   lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;            agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;            cov[2]=agexact;
                   /* Eigen vectors */            if(nagesqr==1)
                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));              cov[3]= agexact*agexact;
                   /*v21=sqrt(1.-v11*v11); *//* error */            for (kk=1; kk<=cptcovage;kk++) {
                   v21=(lc1-v1)/cv12*v11;              cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   v12=-v21;            }
                   v22=v11;          
                   tnalp=v21/v11;            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   if(first1==1){                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                     first1=0;            savm=oldm;
                     printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);            oldm=newm;
                   }          } /* end mult */
                   fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);        
                   /*printf(fignu*/          s1=s[mw[mi][i]][i];
                   /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */          s2=s[mw[mi+1][i]][i];
                   /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */          if( s2 > nlstate){ 
                   if(first==1){            lli=log(out[s1][s2] - savm[s1][s2]);
                     first=0;          }else{
                     fprintf(ficgp,"\nset parametric;unset label");            lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                     fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);          }
                     fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");          ipmx +=1;
                     fprintf(fichtm,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup> :<a href=\"varpijgr%s%d%1d%1d-%1d%1d.png\">varpijgr%s%d%1d%1d-%1d%1d.png</A>, ",k1,l1,k2,l2,optionfilefiname, j1,k1,l1,k2,l2,optionfilefiname, j1,k1,l1,k2,l2);          sw += weight[i];
                     fprintf(fichtm,"\n<br><img src=\"varpijgr%s%d%1d%1d-%1d%1d.png\"> ",optionfilefiname, j1,k1,l1,k2,l2);          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                     fprintf(ficgp,"\nset out \"varpijgr%s%d%1d%1d-%1d%1d.png\"",optionfilefiname, j1,k1,l1,k2,l2);  /*      printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
                     fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);        } /* end of wave */
                     fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);      } /* end of individual */
                     fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",\    }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                             mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),\      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                             mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));        for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   }else{        for(mi=1; mi<= wav[i]-1; mi++){
                     first=0;          for (ii=1;ii<=nlstate+ndeath;ii++)
                     fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);            for (j=1;j<=nlstate+ndeath;j++){
                     fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                     fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",\              savm[ii][j]=(ii==j ? 1.0 : 0.0);
                             mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),\            }
                             mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));          for(d=0; d<dh[mi][i]; d++){
                   }/* if first */            newm=savm;
                 } /* age mod 5 */            agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
               } /* end loop age */            cov[2]=agexact;
               fprintf(ficgp,"\nset out \"varpijgr%s%d%1d%1d-%1d%1d.png\";replot;",optionfilefiname, j1,k1,l1,k2,l2);            if(nagesqr==1)
               first=1;              cov[3]= agexact*agexact;
             } /*l12 */            for (kk=1; kk<=cptcovage;kk++) {
           } /* k12 */              cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
         } /*l1 */            }
       }/* k1 */          
     } /* loop covariates */            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
     free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
     free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));            savm=oldm;
     free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));            oldm=newm;
     free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);          } /* end mult */
     free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);        
     free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);          s1=s[mw[mi][i]][i];
   }          s2=s[mw[mi+1][i]][i];
   free_vector(xp,1,npar);          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
   fclose(ficresprob);          ipmx +=1;
   fclose(ficresprobcov);          sw += weight[i];
   fclose(ficresprobcor);          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
   fclose(ficgp);          /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
   fclose(fichtm);        } /* end of wave */
 }      } /* end of individual */
     } /* End of if */
     for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
 /******************* Printing html file ***********/    /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
 void printinghtml(char fileres[], char title[], char datafile[], int firstpass, \    l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   int lastpass, int stepm, int weightopt, char model[],\    return -l;
                   int imx,int jmin, int jmax, double jmeanint,char rfileres[],\  }
                   int popforecast, int estepm ,\  
                   double jprev1, double mprev1,double anprev1, \  /*************** log-likelihood *************/
                   double jprev2, double mprev2,double anprev2){  double funcone( double *x)
   int jj1, k1, i1, cpt;  {
   /*char optionfilehtm[FILENAMELENGTH];*/    /* Same as likeli but slower because of a lot of printf and if */
   if((fichtm=fopen(optionfilehtm,"a"))==NULL)    {    int i, ii, j, k, mi, d, kk;
     printf("Problem with %s \n",optionfilehtm), exit(0);    double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
     fprintf(ficlog,"Problem with %s \n",optionfilehtm), exit(0);    double **out;
   }    double lli; /* Individual log likelihood */
     double llt;
    fprintf(fichtm,"<ul><li><h4>Result files (first order: no variance)</h4>\n    int s1, s2;
  - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"p%s\">p%s</a> <br>\n    double bbh, survp;
  - Estimated transition probabilities over %d (stepm) months: <a href=\"pij%s\">pij%s</a><br>\n    double agexact;
  - Stable prevalence in each health state: <a href=\"pl%s\">pl%s</a> <br>\n    /*extern weight */
  - Life expectancies by age and initial health status (estepm=%2d months):    /* We are differentiating ll according to initial status */
    <a href=\"e%s\">e%s</a> <br>\n</li>", \    /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
   jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,fileres,fileres,stepm,fileres,fileres,fileres,fileres,estepm,fileres,fileres);    /*for(i=1;i<imx;i++) 
       printf(" %d\n",s[4][i]);
 fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");    */
     cov[1]=1.;
  m=cptcoveff;  
  if (cptcovn < 1) {m=1;ncodemax[1]=1;}    for(k=1; k<=nlstate; k++) ll[k]=0.;
   
  jj1=0;    for (i=1,ipmx=0, sw=0.; i<=imx; i++){
  for(k1=1; k1<=m;k1++){      for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
    for(i1=1; i1<=ncodemax[k1];i1++){      for(mi=1; mi<= wav[i]-1; mi++){
      jj1++;        for (ii=1;ii<=nlstate+ndeath;ii++)
      if (cptcovn > 0) {          for (j=1;j<=nlstate+ndeath;j++){
        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
        for (cpt=1; cpt<=cptcoveff;cpt++)            savm[ii][j]=(ii==j ? 1.0 : 0.0);
          fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtab[jj1][cpt]]);          }
        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");        for(d=0; d<dh[mi][i]; d++){
      }          newm=savm;
      /* Pij */          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
      fprintf(fichtm,"<br>- Pij or Conditional probabilities to be observed in state j being in state i %d (stepm) months before: pe%s%d1.png<br>          cov[2]=agexact;
 <img src=\"pe%s%d1.png\">",stepm,strtok(optionfile, "."),jj1,strtok(optionfile, "."),jj1);              if(nagesqr==1)
      /* Quasi-incidences */            cov[3]= agexact*agexact;
      fprintf(fichtm,"<br>- Pij or Conditional probabilities to be observed in state j being in state i %d (stepm) months before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too: pe%s%d2.png<br>          for (kk=1; kk<=cptcovage;kk++) {
 <img src=\"pe%s%d2.png\">",stepm,strtok(optionfile, "."),jj1,strtok(optionfile, "."),jj1);            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
        /* Stable prevalence in each health state */          }
        for(cpt=1; cpt<nlstate;cpt++){  
          fprintf(fichtm,"<br>- Stable prevalence in each health state : p%s%d%d.png<br>          /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
 <img src=\"p%s%d%d.png\">",strtok(optionfile, "."),cpt,jj1,strtok(optionfile, "."),cpt,jj1);          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
        }                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
      for(cpt=1; cpt<=nlstate;cpt++) {          /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
         fprintf(fichtm,"\n<br>- Health life expectancies by age and initial health state (%d): exp%s%d%d.png <br>          /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
 <img src=\"exp%s%d%d.png\">",cpt,strtok(optionfile, "."),cpt,jj1,strtok(optionfile, "."),cpt,jj1);          savm=oldm;
      }          oldm=newm;
      fprintf(fichtm,"\n<br>- Total life expectancy by age and        } /* end mult */
 health expectancies in states (1) and (2): e%s%d.png<br>        
 <img src=\"e%s%d.png\">",strtok(optionfile, "."),jj1,strtok(optionfile, "."),jj1);        s1=s[mw[mi][i]][i];
    } /* end i1 */        s2=s[mw[mi+1][i]][i];
  }/* End k1 */        bbh=(double)bh[mi][i]/(double)stepm; 
  fprintf(fichtm,"</ul>");        /* bias is positive if real duration
          * is higher than the multiple of stepm and negative otherwise.
          */
  fprintf(fichtm,"\n<br><li><h4> Result files (second order: variances)</h4>\n        if( s2 > nlstate && (mle <5) ){  /* Jackson */
  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br>\n          lli=log(out[s1][s2] - savm[s1][s2]);
  - Variance of one-step probabilities: <a href=\"prob%s\">prob%s</a> <br>\n        } else if  (s2==-2) {
  - Variance-covariance of one-step probabilities: <a href=\"probcov%s\">probcov%s</a> <br>\n          for (j=1,survp=0. ; j<=nlstate; j++) 
  - Correlation matrix of one-step probabilities: <a href=\"probcor%s\">probcor%s</a> <br>\n            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
  - Variances and covariances of life expectancies by age and initial health status (estepm=%d months): <a href=\"v%s\">v%s</a><br>\n          lli= log(survp);
  - Health expectancies with their variances (no covariance): <a href=\"t%s\">t%s</a> <br>\n        }else if (mle==1){
  - Standard deviation of stable prevalences: <a href=\"vpl%s\">vpl%s</a> <br>\n",rfileres,rfileres,fileres,fileres,fileres,fileres,fileres,fileres, estepm, fileres,fileres,fileres,fileres,fileres,fileres);          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
         } else if(mle==2){
  if(popforecast==1) fprintf(fichtm,"\n          lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n        } else if(mle==3){  /* exponential inter-extrapolation */
  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n          lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
         <br>",fileres,fileres,fileres,fileres);        } else if (mle==4){  /* mle=4 no inter-extrapolation */
  else          lli=log(out[s1][s2]); /* Original formula */
    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model);        } else{  /* mle=0 back to 1 */
 fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
           /*lli=log(out[s1][s2]); */ /* Original formula */
  m=cptcoveff;        } /* End of if */
  if (cptcovn < 1) {m=1;ncodemax[1]=1;}        ipmx +=1;
         sw += weight[i];
  jj1=0;        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
  for(k1=1; k1<=m;k1++){        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
    for(i1=1; i1<=ncodemax[k1];i1++){        if(globpr){
      jj1++;          fprintf(ficresilk,"%9ld %6d %2d %2d %1d %1d %3d %11.6f %8.4f\
      if (cptcovn > 0) {   %11.6f %11.6f %11.6f ", \
        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");                  num[i],i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],
        for (cpt=1; cpt<=cptcoveff;cpt++)                  2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
          fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtab[jj1][cpt]]);          for(k=1,llt=0.,l=0.; k<=nlstate; k++){
        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");            llt +=ll[k]*gipmx/gsw;
      }            fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
      for(cpt=1; cpt<=nlstate;cpt++) {          }
        fprintf(fichtm,"<br>- Observed and stationary prevalence (with confident          fprintf(ficresilk," %10.6f\n", -llt);
 interval) in state (%d): v%s%d%d.png <br>        }
 <img src=\"v%s%d%d.png\">",cpt,strtok(optionfile, "."),cpt,jj1,strtok(optionfile, "."),cpt,jj1);        } /* end of wave */
      }    } /* end of individual */
    } /* end i1 */    for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
  }/* End k1 */    /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
  fprintf(fichtm,"</ul>");    l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
 fclose(fichtm);    if(globpr==0){ /* First time we count the contributions and weights */
 }      gipmx=ipmx;
       gsw=sw;
 /******************* Gnuplot file **************/    }
 void printinggnuplot(char fileres[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){    return -l;
   }
   int m,cpt,k1,i,k,j,jk,k2,k3,ij,l;  
   int ng;  
   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) {  /*************** function likelione ***********/
     printf("Problem with file %s",optionfilegnuplot);  void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
     fprintf(ficlog,"Problem with file %s",optionfilegnuplot);  {
   }    /* This routine should help understanding what is done with 
        the selection of individuals/waves and
 #ifdef windows       to check the exact contribution to the likelihood.
     fprintf(ficgp,"cd \"%s\" \n",pathc);       Plotting could be done.
 #endif     */
 m=pow(2,cptcoveff);    int k;
    
  /* 1eme*/    if(*globpri !=0){ /* Just counts and sums, no printings */
   for (cpt=1; cpt<= nlstate ; cpt ++) {      strcpy(fileresilk,"ILK_"); 
    for (k1=1; k1<= m ; k1 ++) {      strcat(fileresilk,fileres);
       if((ficresilk=fopen(fileresilk,"w"))==NULL) {
 #ifdef windows        printf("Problem with resultfile: %s\n", fileresilk);
      fprintf(ficgp,"\nset out \"v%s%d%d.png\" \n",strtok(optionfile, "."),cpt,k1);        fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
      fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter png small\nset size 0.65,0.65\nplot [%.f:%.f] \"vpl%s\" every :::%d::%d u 1:2 \"\%%lf",ageminpar,fage,fileres,k1-1,k1-1);      }
 #endif      fprintf(ficresilk, "#individual(line's_record) s1 s2 wave# effective_wave# number_of_matrices_product pij weight -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
 #ifdef unix      fprintf(ficresilk, "#num_i i s1 s2 mi mw dh likeli weight 2wlli out sav ");
 fprintf(ficgp,"\nset out \"v%s%d%d.png\" \n",strtok(optionfile, "."),cpt,k1);      /*  i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
 fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nplot [%.f:%.f] \"vpl%s\" u 1:2 \"\%%lf",ageminpar,fage,fileres);      for(k=1; k<=nlstate; k++) 
 #endif        fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
       fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
 for (i=1; i<= nlstate ; i ++) {    }
   if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");  
   else fprintf(ficgp," \%%*lf (\%%*lf)");    *fretone=(*funcone)(p);
 }    if(*globpri !=0){
     fprintf(ficgp,"\" t\"Stationary prevalence\" w l 0,\"vpl%s\" every :::%d::%d u 1:($2+2*$3) \"\%%lf",fileres,k1-1,k1-1);      fclose(ficresilk);
     for (i=1; i<= nlstate ; i ++) {      fprintf(fichtm,"\n<br>File of contributions to the likelihood (if mle=1): <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
   if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");      fflush(fichtm); 
   else fprintf(ficgp," \%%*lf (\%%*lf)");    } 
 }    return;
   fprintf(ficgp,"\" t\"95\%% CI\" w l 1,\"vpl%s\" every :::%d::%d u 1:($2-2*$3) \"\%%lf",fileres,k1-1,k1-1);  }
      for (i=1; i<= nlstate ; i ++) {  
   if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");  
   else fprintf(ficgp," \%%*lf (\%%*lf)");  /*********** Maximum Likelihood Estimation ***************/
 }    
      fprintf(ficgp,"\" t\"\" w l 1,\"p%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence \" w l 2",fileres,k1-1,k1-1,2+4*(cpt-1));  void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
 #ifdef unix  {
 fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65\n");    int i,j, iter=0;
 #endif    double **xi;
    }    double fret;
   }    double fretone; /* Only one call to likelihood */
   /*2 eme*/    /*  char filerespow[FILENAMELENGTH];*/
   
   for (k1=1; k1<= m ; k1 ++) {  #ifdef NLOPT
     fprintf(ficgp,"\nset out \"e%s%d.png\" \n",strtok(optionfile, "."),k1);    int creturn;
     fprintf(ficgp,"set ylabel \"Years\" \nset ter png small\nset size 0.65,0.65\nplot [%.f:%.f] ",ageminpar,fage);    nlopt_opt opt;
        /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
     for (i=1; i<= nlstate+1 ; i ++) {    double *lb;
       k=2*i;    double minf; /* the minimum objective value, upon return */
       fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:2 \"\%%lf",fileres,k1-1,k1-1);    double * p1; /* Shifted parameters from 0 instead of 1 */
       for (j=1; j<= nlstate+1 ; j ++) {    myfunc_data dinst, *d = &dinst;
   if (j==i) fprintf(ficgp," \%%lf (\%%lf)");  #endif
   else fprintf(ficgp," \%%*lf (\%%*lf)");  
 }    
       if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l ,");    xi=matrix(1,npar,1,npar);
       else fprintf(ficgp,"\" t\"LE in state (%d)\" w l ,",i-1);    for (i=1;i<=npar;i++)
     fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:($2-$3*2) \"\%%lf",fileres,k1-1,k1-1);      for (j=1;j<=npar;j++)
       for (j=1; j<= nlstate+1 ; j ++) {        xi[i][j]=(i==j ? 1.0 : 0.0);
         if (j==i) fprintf(ficgp," \%%lf (\%%lf)");    printf("Powell\n");  fprintf(ficlog,"Powell\n");
         else fprintf(ficgp," \%%*lf (\%%*lf)");    strcpy(filerespow,"POW_"); 
 }      strcat(filerespow,fileres);
       fprintf(ficgp,"\" t\"\" w l 0,");    if((ficrespow=fopen(filerespow,"w"))==NULL) {
      fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:($2+$3*2) \"\%%lf",fileres,k1-1,k1-1);      printf("Problem with resultfile: %s\n", filerespow);
       for (j=1; j<= nlstate+1 ; j ++) {      fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
   if (j==i) fprintf(ficgp," \%%lf (\%%lf)");    }
   else fprintf(ficgp," \%%*lf (\%%*lf)");    fprintf(ficrespow,"# Powell\n# iter -2*LL");
 }      for (i=1;i<=nlstate;i++)
       if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l 0");      for(j=1;j<=nlstate+ndeath;j++)
       else fprintf(ficgp,"\" t\"\" w l 0,");        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
     }    fprintf(ficrespow,"\n");
   }  #ifdef POWELL
      powell(p,xi,npar,ftol,&iter,&fret,func);
   /*3eme*/  #endif
   
   for (k1=1; k1<= m ; k1 ++) {  #ifdef NLOPT
     for (cpt=1; cpt<= nlstate ; cpt ++) {  #ifdef NEWUOA
       k=2+nlstate*(2*cpt-2);    opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
       fprintf(ficgp,"\nset out \"exp%s%d%d.png\" \n",strtok(optionfile, "."),cpt,k1);  #else
       fprintf(ficgp,"set ter png small\nset size 0.65,0.65\nplot [%.f:%.f] \"e%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,fileres,k1-1,k1-1,k,cpt);    opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
       /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);  #endif
  for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");    lb=vector(0,npar-1);
 fprintf(ficgp,"\" t \"e%d1\" w l",cpt);    for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
 fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);    nlopt_set_lower_bounds(opt, lb);
  for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");    nlopt_set_initial_step1(opt, 0.1);
 fprintf(ficgp,"\" t \"e%d1\" w l",cpt);    
     p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
 */    d->function = func;
       for (i=1; i< nlstate ; i ++) {    printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
         fprintf(ficgp," ,\"e%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",fileres,k1-1,k1-1,k+2*i,cpt,i+1);    nlopt_set_min_objective(opt, myfunc, d);
     nlopt_set_xtol_rel(opt, ftol);
       }    if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
     }      printf("nlopt failed! %d\n",creturn); 
   }    }
      else {
   /* CV preval stat */      printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
     for (k1=1; k1<= m ; k1 ++) {      printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
     for (cpt=1; cpt<nlstate ; cpt ++) {      iter=1; /* not equal */
       k=3;    }
       fprintf(ficgp,"\nset out \"p%s%d%d.png\" \n",strtok(optionfile, "."),cpt,k1);    nlopt_destroy(opt);
       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter png small\nset size 0.65,0.65\nplot [%.f:%.f] \"pij%s\" u ($1==%d ? ($3):1/0):($%d/($%d",ageminpar,agemaxpar,fileres,k1,k+cpt+1,k+1);  #endif
     free_matrix(xi,1,npar,1,npar);
       for (i=1; i< nlstate ; i ++)    fclose(ficrespow);
         fprintf(ficgp,"+$%d",k+i+1);    printf("#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
       fprintf(ficgp,")) t\"prev(%d,%d)\" w l",cpt,cpt+1);    fprintf(ficlog,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
          fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
       l=3+(nlstate+ndeath)*cpt;  
       fprintf(ficgp,",\"pij%s\" u ($1==%d ? ($3):1/0):($%d/($%d",fileres,k1,l+cpt+1,l+1);  }
       for (i=1; i< nlstate ; i ++) {  
         l=3+(nlstate+ndeath)*cpt;  /**** Computes Hessian and covariance matrix ***/
         fprintf(ficgp,"+$%d",l+i+1);  void hesscov(double **matcov, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
       }  {
       fprintf(ficgp,")) t\"prev(%d,%d)\" w l\n",cpt+1,cpt+1);      double  **a,**y,*x,pd;
     }    double **hess;
   }      int i, j;
      int *indx;
   /* proba elementaires */  
    for(i=1,jk=1; i <=nlstate; i++){    double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
     for(k=1; k <=(nlstate+ndeath); k++){    double hessij(double p[], double delti[], int i, int j,double (*func)(double []),int npar);
       if (k != i) {    void lubksb(double **a, int npar, int *indx, double b[]) ;
         for(j=1; j <=ncovmodel; j++){    void ludcmp(double **a, int npar, int *indx, double *d) ;
           fprintf(ficgp,"p%d=%f ",jk,p[jk]);    double gompertz(double p[]);
           jk++;    hess=matrix(1,npar,1,npar);
           fprintf(ficgp,"\n");  
         }    printf("\nCalculation of the hessian matrix. Wait...\n");
       }    fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
     }    for (i=1;i<=npar;i++){
    }      printf("%d",i);fflush(stdout);
       fprintf(ficlog,"%d",i);fflush(ficlog);
    for(ng=1; ng<=2;ng++){ /* Number of graphics: first is probabilities second is incidence per year*/     
      for(jk=1; jk <=m; jk++) {       hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
        fprintf(ficgp,"\nset out \"pe%s%d%d.png\" \n",strtok(optionfile, "."),jk,ng);      
        if (ng==2)      /*  printf(" %f ",p[i]);
          fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");          printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
        else    }
          fprintf(ficgp,"\nset title \"Probability\"\n");    
        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65\nset log y\nplot  [%.f:%.f] ",ageminpar,agemaxpar);    for (i=1;i<=npar;i++) {
        i=1;      for (j=1;j<=npar;j++)  {
        for(k2=1; k2<=nlstate; k2++) {        if (j>i) { 
          k3=i;          printf(".%d%d",i,j);fflush(stdout);
          for(k=1; k<=(nlstate+ndeath); k++) {          fprintf(ficlog,".%d%d",i,j);fflush(ficlog);
            if (k != k2){          hess[i][j]=hessij(p,delti,i,j,func,npar);
              if(ng==2)          
                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);          hess[j][i]=hess[i][j];    
              else          /*printf(" %lf ",hess[i][j]);*/
                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);        }
              ij=1;      }
              for(j=3; j <=ncovmodel; j++) {    }
                if(((j-2)==Tage[ij]) &&(ij <=cptcovage)) {    printf("\n");
                  fprintf(ficgp,"+p%d*%d*x",i+j-1,nbcode[Tvar[j-2]][codtab[jk][Tvar[j-2]]]);    fprintf(ficlog,"\n");
                  ij++;  
                }    printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                else    fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                  fprintf(ficgp,"+p%d*%d",i+j-1,nbcode[Tvar[j-2]][codtab[jk][j-2]]);    
              }    a=matrix(1,npar,1,npar);
              fprintf(ficgp,")/(1");    y=matrix(1,npar,1,npar);
                  x=vector(1,npar);
              for(k1=1; k1 <=nlstate; k1++){      indx=ivector(1,npar);
                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);    for (i=1;i<=npar;i++)
                ij=1;      for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                for(j=3; j <=ncovmodel; j++){    ludcmp(a,npar,indx,&pd);
                  if(((j-2)==Tage[ij]) &&(ij <=cptcovage)) {  
                    fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2,nbcode[Tvar[j-2]][codtab[jk][Tvar[j-2]]]);    for (j=1;j<=npar;j++) {
                    ij++;      for (i=1;i<=npar;i++) x[i]=0;
                  }      x[j]=1;
                  else      lubksb(a,npar,indx,x);
                    fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2,nbcode[Tvar[j-2]][codtab[jk][j-2]]);      for (i=1;i<=npar;i++){ 
                }        matcov[i][j]=x[i];
                fprintf(ficgp,")");      }
              }    }
              fprintf(ficgp,") t \"p%d%d\" ", k2,k);  
              if ((k+k2)!= (nlstate*2+ndeath)) fprintf(ficgp,",");    printf("\n#Hessian matrix#\n");
              i=i+ncovmodel;    fprintf(ficlog,"\n#Hessian matrix#\n");
            }    for (i=1;i<=npar;i++) { 
          } /* end k */      for (j=1;j<=npar;j++) { 
        } /* end k2 */        printf("%.3e ",hess[i][j]);
      } /* end jk */        fprintf(ficlog,"%.3e ",hess[i][j]);
    } /* end ng */      }
    fclose(ficgp);      printf("\n");
 }  /* end gnuplot */      fprintf(ficlog,"\n");
     }
   
 /*************** Moving average **************/    /* Recompute Inverse */
 void movingaverage(double agedeb, double fage,double ageminpar, double ***mobaverage){    for (i=1;i<=npar;i++)
       for (j=1;j<=npar;j++) a[i][j]=matcov[i][j];
   int i, cpt, cptcod;    ludcmp(a,npar,indx,&pd);
     for (agedeb=ageminpar; agedeb<=fage; agedeb++)  
       for (i=1; i<=nlstate;i++)    /*  printf("\n#Hessian matrix recomputed#\n");
         for (cptcod=1;cptcod<=ncodemax[cptcov];cptcod++)  
           mobaverage[(int)agedeb][i][cptcod]=0.;    for (j=1;j<=npar;j++) {
          for (i=1;i<=npar;i++) x[i]=0;
     for (agedeb=ageminpar+4; agedeb<=fage; agedeb++){      x[j]=1;
       for (i=1; i<=nlstate;i++){      lubksb(a,npar,indx,x);
         for (cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){      for (i=1;i<=npar;i++){ 
           for (cpt=0;cpt<=4;cpt++){        y[i][j]=x[i];
             mobaverage[(int)agedeb-2][i][cptcod]=mobaverage[(int)agedeb-2][i][cptcod]+probs[(int)agedeb-cpt][i][cptcod];        printf("%.3e ",y[i][j]);
           }        fprintf(ficlog,"%.3e ",y[i][j]);
           mobaverage[(int)agedeb-2][i][cptcod]=mobaverage[(int)agedeb-2][i][cptcod]/5;      }
         }      printf("\n");
       }      fprintf(ficlog,"\n");
     }    }
        */
 }  
     free_matrix(a,1,npar,1,npar);
     free_matrix(y,1,npar,1,npar);
 /************** Forecasting ******************/    free_vector(x,1,npar);
 prevforecast(char fileres[], double anproj1,double mproj1,double jproj1,double ageminpar, double agemax,double dateprev1, double dateprev2, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anproj2,double p[], int i2){    free_ivector(indx,1,npar);
      free_matrix(hess,1,npar,1,npar);
   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h;  
   int *popage;  
   double calagedate, agelim, kk1, kk2, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;  }
   double *popeffectif,*popcount;  
   double ***p3mat;  /*************** hessian matrix ****************/
   char fileresf[FILENAMELENGTH];  double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
   {
  agelim=AGESUP;    int i;
 calagedate=(anproj1+mproj1/12.+jproj1/365.-dateintmean)*YEARM;    int l=1, lmax=20;
     double k1,k2;
   prevalence(ageminpar, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax,mint,anint,dateprev1,dateprev2, calagedate);    double p2[MAXPARM+1]; /* identical to x */
      double res;
      double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
   strcpy(fileresf,"f");    double fx;
   strcat(fileresf,fileres);    int k=0,kmax=10;
   if((ficresf=fopen(fileresf,"w"))==NULL) {    double l1;
     printf("Problem with forecast resultfile: %s\n", fileresf);  
     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);    fx=func(x);
   }    for (i=1;i<=npar;i++) p2[i]=x[i];
   printf("Computing forecasting: result on file '%s' \n", fileresf);    for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", fileresf);      l1=pow(10,l);
       delts=delt;
   if (cptcoveff==0) ncodemax[cptcoveff]=1;      for(k=1 ; k <kmax; k=k+1){
         delt = delta*(l1*k);
   if (mobilav==1) {        p2[theta]=x[theta] +delt;
     mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);        k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
     movingaverage(agedeb, fage, ageminpar, mobaverage);        p2[theta]=x[theta]-delt;
   }        k2=func(p2)-fx;
         /*res= (k1-2.0*fx+k2)/delt/delt; */
   stepsize=(int) (stepm+YEARM-1)/YEARM;        res= (k1+k2)/delt/delt/2.; /* Divided by because L and not 2*L */
   if (stepm<=12) stepsize=1;        
    #ifdef DEBUGHESS
   agelim=AGESUP;        printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
          fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
   hstepm=1;  #endif
   hstepm=hstepm/stepm;        /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
   yp1=modf(dateintmean,&yp);        if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
   anprojmean=yp;          k=kmax;
   yp2=modf((yp1*12),&yp);        }
   mprojmean=yp;        else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
   yp1=modf((yp2*30.5),&yp);          k=kmax; l=lmax*10;
   jprojmean=yp;        }
   if(jprojmean==0) jprojmean=1;        else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
   if(mprojmean==0) jprojmean=1;          delts=delt;
          }
   fprintf(ficresf,"# Estimated date of observed prevalence: %.lf/%.lf/%.lf ",jprojmean,mprojmean,anprojmean);      }
      }
   for(cptcov=1;cptcov<=i2;cptcov++){    delti[theta]=delts;
     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){    return res; 
       k=k+1;    
       fprintf(ficresf,"\n#******");  }
       for(j=1;j<=cptcoveff;j++) {  
         fprintf(ficresf," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);  double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
       }  {
       fprintf(ficresf,"******\n");    int i;
       fprintf(ficresf,"# StartingAge FinalAge");    int l=1, lmax=20;
       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficresf," P.%d",j);    double k1,k2,k3,k4,res,fx;
          double p2[MAXPARM+1];
          int k;
       for (cpt=0; cpt<=(anproj2-anproj1);cpt++) {  
         fprintf(ficresf,"\n");    fx=func(x);
         fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+cpt);      for (k=1; k<=2; k++) {
       for (i=1;i<=npar;i++) p2[i]=x[i];
         for (agedeb=(fage-((int)calagedate %12/12.)); agedeb>=(ageminpar-((int)calagedate %12)/12.); agedeb--){      p2[thetai]=x[thetai]+delti[thetai]/k;
           nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);      p2[thetaj]=x[thetaj]+delti[thetaj]/k;
           nhstepm = nhstepm/hstepm;      k1=func(p2)-fx;
              
           p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);      p2[thetai]=x[thetai]+delti[thetai]/k;
           oldm=oldms;savm=savms;      p2[thetaj]=x[thetaj]-delti[thetaj]/k;
           hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);        k2=func(p2)-fx;
            
           for (h=0; h<=nhstepm; h++){      p2[thetai]=x[thetai]-delti[thetai]/k;
             if (h==(int) (calagedate+YEARM*cpt)) {      p2[thetaj]=x[thetaj]+delti[thetaj]/k;
               fprintf(ficresf,"\n %.f %.f ",anproj1+cpt,agedeb+h*hstepm/YEARM*stepm);      k3=func(p2)-fx;
             }    
             for(j=1; j<=nlstate+ndeath;j++) {      p2[thetai]=x[thetai]-delti[thetai]/k;
               kk1=0.;kk2=0;      p2[thetaj]=x[thetaj]-delti[thetaj]/k;
               for(i=1; i<=nlstate;i++) {                    k4=func(p2)-fx;
                 if (mobilav==1)      res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /* Because of L not 2*L */
                   kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod];  #ifdef DEBUG
                 else {      printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod];      fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                 }  #endif
                    }
               }    return res;
               if (h==(int)(calagedate+12*cpt)){  }
                 fprintf(ficresf," %.3f", kk1);  
                          /************** Inverse of matrix **************/
               }  void ludcmp(double **a, int n, int *indx, double *d) 
             }  { 
           }    int i,imax,j,k; 
           free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);    double big,dum,sum,temp; 
         }    double *vv; 
       }   
     }    vv=vector(1,n); 
   }    *d=1.0; 
            for (i=1;i<=n;i++) { 
   if (mobilav==1) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);      big=0.0; 
       for (j=1;j<=n;j++) 
   fclose(ficresf);        if ((temp=fabs(a[i][j])) > big) big=temp; 
 }      if (big == 0.0) nrerror("Singular matrix in routine ludcmp"); 
 /************** Forecasting ******************/      vv[i]=1.0/big; 
 populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){    } 
      for (j=1;j<=n;j++) { 
   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h;      for (i=1;i<j;i++) { 
   int *popage;        sum=a[i][j]; 
   double calagedate, agelim, kk1, kk2, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;        for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
   double *popeffectif,*popcount;        a[i][j]=sum; 
   double ***p3mat,***tabpop,***tabpopprev;      } 
   char filerespop[FILENAMELENGTH];      big=0.0; 
       for (i=j;i<=n;i++) { 
   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);        sum=a[i][j]; 
   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);        for (k=1;k<j;k++) 
   agelim=AGESUP;          sum -= a[i][k]*a[k][j]; 
   calagedate=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM;        a[i][j]=sum; 
          if ( (dum=vv[i]*fabs(sum)) >= big) { 
   prevalence(ageminpar, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax,mint,anint,dateprev1,dateprev2, calagedate);          big=dum; 
            imax=i; 
          } 
   strcpy(filerespop,"pop");      } 
   strcat(filerespop,fileres);      if (j != imax) { 
   if((ficrespop=fopen(filerespop,"w"))==NULL) {        for (k=1;k<=n;k++) { 
     printf("Problem with forecast resultfile: %s\n", filerespop);          dum=a[imax][k]; 
     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop);          a[imax][k]=a[j][k]; 
   }          a[j][k]=dum; 
   printf("Computing forecasting: result on file '%s' \n", filerespop);        } 
   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop);        *d = -(*d); 
         vv[imax]=vv[j]; 
   if (cptcoveff==0) ncodemax[cptcoveff]=1;      } 
       indx[j]=imax; 
   if (mobilav==1) {      if (a[j][j] == 0.0) a[j][j]=TINY; 
     mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);      if (j != n) { 
     movingaverage(agedeb, fage, ageminpar, mobaverage);        dum=1.0/(a[j][j]); 
   }        for (i=j+1;i<=n;i++) a[i][j] *= dum; 
       } 
   stepsize=(int) (stepm+YEARM-1)/YEARM;    } 
   if (stepm<=12) stepsize=1;    free_vector(vv,1,n);  /* Doesn't work */
    ;
   agelim=AGESUP;  } 
    
   hstepm=1;  void lubksb(double **a, int n, int *indx, double b[]) 
   hstepm=hstepm/stepm;  { 
      int i,ii=0,ip,j; 
   if (popforecast==1) {    double sum; 
     if((ficpop=fopen(popfile,"r"))==NULL) {   
       printf("Problem with population file : %s\n",popfile);exit(0);    for (i=1;i<=n;i++) { 
       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0);      ip=indx[i]; 
     }      sum=b[ip]; 
     popage=ivector(0,AGESUP);      b[ip]=b[i]; 
     popeffectif=vector(0,AGESUP);      if (ii) 
     popcount=vector(0,AGESUP);        for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
          else if (sum) ii=i; 
     i=1;        b[i]=sum; 
     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1;    } 
        for (i=n;i>=1;i--) { 
     imx=i;      sum=b[i]; 
     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i];      for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
   }      b[i]=sum/a[i][i]; 
     } 
   for(cptcov=1;cptcov<=i2;cptcov++){  } 
    for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){  
       k=k+1;  void pstamp(FILE *fichier)
       fprintf(ficrespop,"\n#******");  {
       for(j=1;j<=cptcoveff;j++) {    fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
         fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);  }
       }  
       fprintf(ficrespop,"******\n");  /************ Frequencies ********************/
       fprintf(ficrespop,"# Age");  void  freqsummary(char fileres[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, int *Tvaraff, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[])
       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j);  {  /* Some frequencies */
       if (popforecast==1)  fprintf(ficrespop," [Population]");    
          int i, m, jk, j1, bool, z1,j;
       for (cpt=0; cpt<=0;cpt++) {    int first;
         fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);      double ***freq; /* Frequencies */
            double *pp, **prop;
         for (agedeb=(fage-((int)calagedate %12/12.)); agedeb>=(ageminpar-((int)calagedate %12)/12.); agedeb--){    double pos,posprop, k2, dateintsum=0,k2cpt=0;
           nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);    char fileresp[FILENAMELENGTH];
           nhstepm = nhstepm/hstepm;    
              pp=vector(1,nlstate);
           p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);    prop=matrix(1,nlstate,iagemin,iagemax+3);
           oldm=oldms;savm=savms;    strcpy(fileresp,"P_");
           hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);      strcat(fileresp,fileresu);
            if((ficresp=fopen(fileresp,"w"))==NULL) {
           for (h=0; h<=nhstepm; h++){      printf("Problem with prevalence resultfile: %s\n", fileresp);
             if (h==(int) (calagedate+YEARM*cpt)) {      fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
               fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm);      exit(0);
             }    }
             for(j=1; j<=nlstate+ndeath;j++) {    freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin,iagemax+3);
               kk1=0.;kk2=0;    j1=0;
               for(i=1; i<=nlstate;i++) {                  
                 if (mobilav==1)    j=cptcoveff;
                   kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod];    if (cptcovn<1) {j=1;ncodemax[1]=1;}
                 else {  
                   kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod];    first=1;
                 }  
               }    /* for(k1=1; k1<=j ; k1++){ */  /* Loop on covariates */
               if (h==(int)(calagedate+12*cpt)){    /*  for(i1=1; i1<=ncodemax[k1];i1++){ */ /* Now it is 2 */
                 tabpop[(int)(agedeb)][j][cptcod]=kk1;    /*    j1++; */
                   /*fprintf(ficrespop," %.3f", kk1);    for (j1 = 1; j1 <= (int) pow(2,cptcoveff); j1++){
                     if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*/        /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
               }          scanf("%d", i);*/
             }        for (i=-5; i<=nlstate+ndeath; i++)  
             for(i=1; i<=nlstate;i++){          for (jk=-5; jk<=nlstate+ndeath; jk++)  
               kk1=0.;            for(m=iagemin; m <= iagemax+3; m++)
                 for(j=1; j<=nlstate;j++){              freq[i][jk][m]=0;
                   kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];        
                 }        for (i=1; i<=nlstate; i++)  
                   tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedate+12*cpt)*hstepm/YEARM*stepm-1)];          for(m=iagemin; m <= iagemax+3; m++)
             }            prop[i][m]=0;
         
             if (h==(int)(calagedate+12*cpt)) for(j=1; j<=nlstate;j++)        dateintsum=0;
               fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]);        k2cpt=0;
           }        for (i=1; i<=imx; i++) {
           free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);          bool=1;
         }          if  (cptcovn>0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
       }            for (z1=1; z1<=cptcoveff; z1++)       
                if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){
   /******/                  /* Tests if the value of each of the covariates of i is equal to filter j1 */
                 bool=0;
       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {                /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
         fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);                    bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
         for (agedeb=(fage-((int)calagedate %12/12.)); agedeb>=(ageminpar-((int)calagedate %12)/12.); agedeb--){                  j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
           nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);                /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
           nhstepm = nhstepm/hstepm;              } 
                    }
           p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);   
           oldm=oldms;savm=savms;          if (bool==1){
           hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);              for(m=firstpass; m<=lastpass; m++){
           for (h=0; h<=nhstepm; h++){              k2=anint[m][i]+(mint[m][i]/12.);
             if (h==(int) (calagedate+YEARM*cpt)) {              /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
               fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm);                if(agev[m][i]==0) agev[m][i]=iagemax+1;
             }                if(agev[m][i]==1) agev[m][i]=iagemax+2;
             for(j=1; j<=nlstate+ndeath;j++) {                if (s[m][i]>0 && s[m][i]<=nlstate) prop[s[m][i]][(int)agev[m][i]] += weight[i];
               kk1=0.;kk2=0;                if (m<lastpass) {
               for(i=1; i<=nlstate;i++) {                                freq[s[m][i]][s[m+1][i]][(int)agev[m][i]] += weight[i];
                 kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];                      freq[s[m][i]][s[m+1][i]][iagemax+3] += weight[i];
               }                }
               if (h==(int)(calagedate+12*cpt)) fprintf(ficresf," %15.2f", kk1);                
             }                if ((agev[m][i]>1) && (agev[m][i]< (iagemax+3))) {
           }                  dateintsum=dateintsum+k2;
           free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);                  k2cpt++;
         }                }
       }                /*}*/
    }            }
   }          }
          } /* end i */
   if (mobilav==1) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);         
         /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
   if (popforecast==1) {        pstamp(ficresp);
     free_ivector(popage,0,AGESUP);        if  (cptcovn>0) {
     free_vector(popeffectif,0,AGESUP);          fprintf(ficresp, "\n#********** Variable "); 
     free_vector(popcount,0,AGESUP);          for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
   }          fprintf(ficresp, "**********\n#");
   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);          fprintf(ficlog, "\n#********** Variable "); 
   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);          for (z1=1; z1<=cptcoveff; z1++) fprintf(ficlog, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
   fclose(ficrespop);          fprintf(ficlog, "**********\n#");
 }        }
         for(i=1; i<=nlstate;i++) 
 /***********************************************/          fprintf(ficresp, " Age Prev(%d) N(%d) N",i,i);
 /**************** Main Program *****************/        fprintf(ficresp, "\n");
 /***********************************************/        
         for(i=iagemin; i <= iagemax+3; i++){
 int main(int argc, char *argv[])          if(i==iagemax+3){
 {            fprintf(ficlog,"Total");
           }else{
   int i,j, k, n=MAXN,iter,m,size,cptcode, cptcod;            if(first==1){
   double agedeb, agefin,hf;              first=0;
   double ageminpar=1.e20,agemin=1.e20, agemaxpar=-1.e20, agemax=-1.e20;              printf("See log file for details...\n");
             }
   double fret;            fprintf(ficlog,"Age %d", i);
   double **xi,tmp,delta;          }
           for(jk=1; jk <=nlstate ; jk++){
   double dum; /* Dummy variable */            for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
   double ***p3mat;              pp[jk] += freq[jk][m][i]; 
   int *indx;          }
   char line[MAXLINE], linepar[MAXLINE];          for(jk=1; jk <=nlstate ; jk++){
   char path[80],pathc[80],pathcd[80],pathtot[80],model[80];            for(m=-1, pos=0; m <=0 ; m++)
   int firstobs=1, lastobs=10;              pos += freq[jk][m][i];
   int sdeb, sfin; /* Status at beginning and end */            if(pp[jk]>=1.e-10){
   int c,  h , cpt,l;              if(first==1){
   int ju,jl, mi;                printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
   int i1,j1, k1,k2,k3,jk,aa,bb, stepsize, ij;              }
   int jnais,jdc,jint4,jint1,jint2,jint3,**outcome,**adl,*tab;              fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
   int mobilav=0,popforecast=0;            }else{
   int hstepm, nhstepm;              if(first==1)
   double jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,jpyram, mpyram,anpyram,jpyram1, mpyram1,anpyram1, calagedate;                printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
               fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
   double bage, fage, age, agelim, agebase;            }
   double ftolpl=FTOL;          }
   double **prlim;  
   double *severity;          for(jk=1; jk <=nlstate ; jk++){
   double ***param; /* Matrix of parameters */            for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)
   double  *p;              pp[jk] += freq[jk][m][i];
   double **matcov; /* Matrix of covariance */          }       
   double ***delti3; /* Scale */          for(jk=1,pos=0,posprop=0; jk <=nlstate ; jk++){
   double *delti; /* Scale */            pos += pp[jk];
   double ***eij, ***vareij;            posprop += prop[jk][i];
   double **varpl; /* Variances of prevalence limits by age */          }
   double *epj, vepp;          for(jk=1; jk <=nlstate ; jk++){
   double kk1, kk2;            if(pos>=1.e-5){
   double dateprev1, dateprev2,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2;              if(first==1)
                  printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
               fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
   char *alph[]={"a","a","b","c","d","e"}, str[4];            }else{
               if(first==1)
                 printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
   char z[1]="c", occ;              fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
 #include <sys/time.h>            }
 #include <time.h>            if( i <= iagemax){
   char stra[80], strb[80], strc[80], strd[80],stre[80],modelsav[80];              if(pos>=1.e-5){
                  fprintf(ficresp," %d %.5f %.0f %.0f",i,prop[jk][i]/posprop, prop[jk][i],posprop);
   /* long total_usecs;                /*probs[i][jk][j1]= pp[jk]/pos;*/
   struct timeval start_time, end_time;                /*printf("\ni=%d jk=%d j1=%d %.5f %.0f %.0f %f",i,jk,j1,pp[jk]/pos, pp[jk],pos,probs[i][jk][j1]);*/
                }
   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */              else
   getcwd(pathcd, size);                fprintf(ficresp," %d NaNq %.0f %.0f",i,prop[jk][i],posprop);
             }
   printf("\n%s",version);          }
   if(argc <=1){          
     printf("\nEnter the parameter file name: ");          for(jk=-1; jk <=nlstate+ndeath; jk++)
     scanf("%s",pathtot);            for(m=-1; m <=nlstate+ndeath; m++)
   }              if(freq[jk][m][i] !=0 ) {
   else{              if(first==1)
     strcpy(pathtot,argv[1]);                printf(" %d%d=%.0f",jk,m,freq[jk][m][i]);
   }                fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][i]);
   /*if(getcwd(pathcd, 80)!= NULL)printf ("Error pathcd\n");*/              }
   /*cygwin_split_path(pathtot,path,optionfile);          if(i <= iagemax)
     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/            fprintf(ficresp,"\n");
   /* cutv(path,optionfile,pathtot,'\\');*/          if(first==1)
             printf("Others in log...\n");
   split(pathtot,path,optionfile,optionfilext,optionfilefiname);          fprintf(ficlog,"\n");
    printf("pathtot=%s, path=%s, optionfile=%s optionfilext=%s optionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);        }
   chdir(path);        /*}*/
   replace(pathc,path);    }
     dateintmean=dateintsum/k2cpt; 
 /*-------- arguments in the command line --------*/   
     fclose(ficresp);
   /* Log file */    free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin, iagemax+3);
   strcat(filelog, optionfilefiname);    free_vector(pp,1,nlstate);
   strcat(filelog,".log");    /* */    free_matrix(prop,1,nlstate,iagemin, iagemax+3);
   if((ficlog=fopen(filelog,"w"))==NULL)    {    /* End of Freq */
     printf("Problem with logfile %s\n",filelog);  }
     goto end;  
   }  /************ Prevalence ********************/
   fprintf(ficlog,"Log filename:%s\n",filelog);  void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
   fprintf(ficlog,"\n%s",version);  {  
   fprintf(ficlog,"\nEnter the parameter file name: ");    /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
   fprintf(ficlog,"pathtot=%s, path=%s, optionfile=%s optionfilext=%s optionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);       in each health status at the date of interview (if between dateprev1 and dateprev2).
   fflush(ficlog);       We still use firstpass and lastpass as another selection.
     */
   /* */   
   strcpy(fileres,"r");    int i, m, jk, j1, bool, z1,j;
   strcat(fileres, optionfilefiname);  
   strcat(fileres,".txt");    /* Other files have txt extension */    double **prop;
     double posprop; 
   /*---------arguments file --------*/    double  y2; /* in fractional years */
     int iagemin, iagemax;
   if((ficpar=fopen(optionfile,"r"))==NULL)    {    int first; /** to stop verbosity which is redirected to log file */
     printf("Problem with optionfile %s\n",optionfile);  
     fprintf(ficlog,"Problem with optionfile %s\n",optionfile);    iagemin= (int) agemin;
     goto end;    iagemax= (int) agemax;
   }    /*pp=vector(1,nlstate);*/
     prop=matrix(1,nlstate,iagemin,iagemax+3); 
   strcpy(filereso,"o");    /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
   strcat(filereso,fileres);    j1=0;
   if((ficparo=fopen(filereso,"w"))==NULL) {    
     printf("Problem with Output resultfile: %s\n", filereso);    /*j=cptcoveff;*/
     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);    if (cptcovn<1) {j=1;ncodemax[1]=1;}
     goto end;    
   }    first=1;
     for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){
   /* Reads comments: lines beginning with '#' */      /*for(i1=1; i1<=ncodemax[k1];i1++){
   while((c=getc(ficpar))=='#' && c!= EOF){        j1++;*/
     ungetc(c,ficpar);        
     fgets(line, MAXLINE, ficpar);        for (i=1; i<=nlstate; i++)  
     puts(line);          for(m=iagemin; m <= iagemax+3; m++)
     fputs(line,ficparo);            prop[i][m]=0.0;
   }       
   ungetc(c,ficpar);        for (i=1; i<=imx; i++) { /* Each individual */
           bool=1;
   fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model);          if  (cptcovn>0) {
   printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model);            for (z1=1; z1<=cptcoveff; z1++) 
   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model);              if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) 
 while((c=getc(ficpar))=='#' && c!= EOF){                bool=0;
     ungetc(c,ficpar);          } 
     fgets(line, MAXLINE, ficpar);          if (bool==1) { 
     puts(line);            for(m=firstpass; m<=lastpass; m++){/* Other selection (we can limit to certain interviews*/
     fputs(line,ficparo);              y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
   }              if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
   ungetc(c,ficpar);                if(agev[m][i]==0) agev[m][i]=iagemax+1;
                  if(agev[m][i]==1) agev[m][i]=iagemax+2;
                    if((int)agev[m][i] <iagemin || (int)agev[m][i] >iagemax+3) printf("Error on individual =%d agev[m][i]=%f m=%d\n",i, agev[m][i],m); 
   covar=matrix(0,NCOVMAX,1,n);                if (s[m][i]>0 && s[m][i]<=nlstate) { 
   cptcovn=0;                  /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
   if (strlen(model)>1) cptcovn=nbocc(model,'+')+1;                  prop[s[m][i]][(int)agev[m][i]] += weight[i];
                   prop[s[m][i]][iagemax+3] += weight[i]; 
   ncovmodel=2+cptcovn;                } 
   nvar=ncovmodel-1; /* Suppressing age as a basic covariate */              }
              } /* end selection of waves */
   /* Read guess parameters */          }
   /* Reads comments: lines beginning with '#' */        }
   while((c=getc(ficpar))=='#' && c!= EOF){        for(i=iagemin; i <= iagemax+3; i++){  
     ungetc(c,ficpar);          for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
     fgets(line, MAXLINE, ficpar);            posprop += prop[jk][i]; 
     puts(line);          } 
     fputs(line,ficparo);          
   }          for(jk=1; jk <=nlstate ; jk++){     
   ungetc(c,ficpar);            if( i <=  iagemax){ 
                if(posprop>=1.e-5){ 
   param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);                probs[i][jk][j1]= prop[jk][i]/posprop;
     for(i=1; i <=nlstate; i++)              } else{
     for(j=1; j <=nlstate+ndeath-1; j++){                if(first==1){
       fscanf(ficpar,"%1d%1d",&i1,&j1);                  first=0;
       fprintf(ficparo,"%1d%1d",i1,j1);                  printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others on log file...\n",jk,i,j1,probs[i][jk][j1]);
       if(mle==1)                }
         printf("%1d%1d",i,j);              }
       fprintf(ficlog,"%1d%1d",i,j);            } 
       for(k=1; k<=ncovmodel;k++){          }/* end jk */ 
         fscanf(ficpar," %lf",&param[i][j][k]);        }/* end i */ 
         if(mle==1){      /*} *//* end i1 */
           printf(" %lf",param[i][j][k]);    } /* end j1 */
           fprintf(ficlog," %lf",param[i][j][k]);    
         }    /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
         else    /*free_vector(pp,1,nlstate);*/
           fprintf(ficlog," %lf",param[i][j][k]);    free_matrix(prop,1,nlstate, iagemin,iagemax+3);
         fprintf(ficparo," %lf",param[i][j][k]);  }  /* End of prevalence */
       }  
       fscanf(ficpar,"\n");  /************* Waves Concatenation ***************/
       if(mle==1)  
         printf("\n");  void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
       fprintf(ficlog,"\n");  {
       fprintf(ficparo,"\n");    /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
     }       Death is a valid wave (if date is known).
         mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
     npar= (nlstate+ndeath-1)*nlstate*ncovmodel;       dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
        and mw[mi+1][i]. dh depends on stepm.
   p=param[1][1];       */
    
   /* Reads comments: lines beginning with '#' */    int i, mi, m;
   while((c=getc(ficpar))=='#' && c!= EOF){    /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
     ungetc(c,ficpar);       double sum=0., jmean=0.;*/
     fgets(line, MAXLINE, ficpar);    int first;
     puts(line);    int j, k=0,jk, ju, jl;
     fputs(line,ficparo);    double sum=0.;
   }    first=0;
   ungetc(c,ficpar);    jmin=100000;
     jmax=-1;
   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);    jmean=0.;
   delti=vector(1,npar); /* Scale of each paramater (output from hesscov) */    for(i=1; i<=imx; i++){
   for(i=1; i <=nlstate; i++){      mi=0;
     for(j=1; j <=nlstate+ndeath-1; j++){      m=firstpass;
       fscanf(ficpar,"%1d%1d",&i1,&j1);      while(s[m][i] <= nlstate){
       printf("%1d%1d",i,j);        if(s[m][i]>=1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5)
       fprintf(ficparo,"%1d%1d",i1,j1);          mw[++mi][i]=m;
       for(k=1; k<=ncovmodel;k++){        if(m >=lastpass)
         fscanf(ficpar,"%le",&delti3[i][j][k]);          break;
         printf(" %le",delti3[i][j][k]);        else
         fprintf(ficparo," %le",delti3[i][j][k]);          m++;
       }      }/* end while */
       fscanf(ficpar,"\n");      if (s[m][i] > nlstate){
       printf("\n");        mi++;     /* Death is another wave */
       fprintf(ficparo,"\n");        /* if(mi==0)  never been interviewed correctly before death */
     }           /* Only death is a correct wave */
   }        mw[mi][i]=m;
   delti=delti3[1][1];      }
    
   /* Reads comments: lines beginning with '#' */      wav[i]=mi;
   while((c=getc(ficpar))=='#' && c!= EOF){      if(mi==0){
     ungetc(c,ficpar);        nbwarn++;
     fgets(line, MAXLINE, ficpar);        if(first==0){
     puts(line);          printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
     fputs(line,ficparo);          first=1;
   }        }
   ungetc(c,ficpar);        if(first==1){
            fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
   matcov=matrix(1,npar,1,npar);        }
   for(i=1; i <=npar; i++){      } /* end mi==0 */
     fscanf(ficpar,"%s",&str);    } /* End individuals */
     if(mle==1)  
       printf("%s",str);    for(i=1; i<=imx; i++){
     fprintf(ficlog,"%s",str);      for(mi=1; mi<wav[i];mi++){
     fprintf(ficparo,"%s",str);        if (stepm <=0)
     for(j=1; j <=i; j++){          dh[mi][i]=1;
       fscanf(ficpar," %le",&matcov[i][j]);        else{
       if(mle==1){          if (s[mw[mi+1][i]][i] > nlstate) { /* A death */
         printf(" %.5le",matcov[i][j]);            if (agedc[i] < 2*AGESUP) {
         fprintf(ficlog," %.5le",matcov[i][j]);              j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
       }              if(j==0) j=1;  /* Survives at least one month after exam */
       else              else if(j<0){
         fprintf(ficlog," %.5le",matcov[i][j]);                nberr++;
       fprintf(ficparo," %.5le",matcov[i][j]);                printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
     }                j=1; /* Temporary Dangerous patch */
     fscanf(ficpar,"\n");                printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
     if(mle==1)                fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
       printf("\n");                fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
     fprintf(ficlog,"\n");              }
     fprintf(ficparo,"\n");              k=k+1;
   }              if (j >= jmax){
   for(i=1; i <=npar; i++)                jmax=j;
     for(j=i+1;j<=npar;j++)                ijmax=i;
       matcov[i][j]=matcov[j][i];              }
                  if (j <= jmin){
   if(mle==1)                jmin=j;
     printf("\n");                ijmin=i;
   fprintf(ficlog,"\n");              }
               sum=sum+j;
               /*if (j<0) printf("j=%d num=%d \n",j,i);*/
     /*-------- Rewriting paramater file ----------*/              /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
      strcpy(rfileres,"r");    /* "Rparameterfile */            }
      strcat(rfileres,optionfilefiname);    /* Parameter file first name*/          }
      strcat(rfileres,".");    /* */          else{
      strcat(rfileres,optionfilext);    /* Other files have txt extension */            j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
     if((ficres =fopen(rfileres,"w"))==NULL) {  /*        if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
       printf("Problem writing new parameter file: %s\n", fileres);goto end;  
       fprintf(ficlog,"Problem writing new parameter file: %s\n", fileres);goto end;            k=k+1;
     }            if (j >= jmax) {
     fprintf(ficres,"#%s\n",version);              jmax=j;
                  ijmax=i;
     /*-------- data file ----------*/            }
     if((fic=fopen(datafile,"r"))==NULL)    {            else if (j <= jmin){
       printf("Problem with datafile: %s\n", datafile);goto end;              jmin=j;
       fprintf(ficlog,"Problem with datafile: %s\n", datafile);goto end;              ijmin=i;
     }            }
             /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
     n= lastobs;            /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
     severity = vector(1,maxwav);            if(j<0){
     outcome=imatrix(1,maxwav+1,1,n);              nberr++;
     num=ivector(1,n);              printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
     moisnais=vector(1,n);              fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
     annais=vector(1,n);            }
     moisdc=vector(1,n);            sum=sum+j;
     andc=vector(1,n);          }
     agedc=vector(1,n);          jk= j/stepm;
     cod=ivector(1,n);          jl= j -jk*stepm;
     weight=vector(1,n);          ju= j -(jk+1)*stepm;
     for(i=1;i<=n;i++) weight[i]=1.0; /* Equal weights, 1 by default */          if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
     mint=matrix(1,maxwav,1,n);            if(jl==0){
     anint=matrix(1,maxwav,1,n);              dh[mi][i]=jk;
     s=imatrix(1,maxwav+1,1,n);              bh[mi][i]=0;
     adl=imatrix(1,maxwav+1,1,n);                }else{ /* We want a negative bias in order to only have interpolation ie
     tab=ivector(1,NCOVMAX);                    * to avoid the price of an extra matrix product in likelihood */
     ncodemax=ivector(1,8);              dh[mi][i]=jk+1;
               bh[mi][i]=ju;
     i=1;            }
     while (fgets(line, MAXLINE, fic) != NULL)    {          }else{
       if ((i >= firstobs) && (i <=lastobs)) {            if(jl <= -ju){
                      dh[mi][i]=jk;
         for (j=maxwav;j>=1;j--){              bh[mi][i]=jl;       /* bias is positive if real duration
           cutv(stra, strb,line,' '); s[j][i]=atoi(strb);                                   * is higher than the multiple of stepm and negative otherwise.
           strcpy(line,stra);                                   */
           cutv(stra, strb,line,'/'); anint[j][i]=(double)(atoi(strb)); strcpy(line,stra);            }
           cutv(stra, strb,line,' '); mint[j][i]=(double)(atoi(strb)); strcpy(line,stra);            else{
         }              dh[mi][i]=jk+1;
                      bh[mi][i]=ju;
         cutv(stra, strb,line,'/'); andc[i]=(double)(atoi(strb)); strcpy(line,stra);            }
         cutv(stra, strb,line,' '); moisdc[i]=(double)(atoi(strb)); strcpy(line,stra);            if(dh[mi][i]==0){
               dh[mi][i]=1; /* At least one step */
         cutv(stra, strb,line,'/'); annais[i]=(double)(atoi(strb)); strcpy(line,stra);              bh[mi][i]=ju; /* At least one step */
         cutv(stra, strb,line,' '); moisnais[i]=(double)(atoi(strb)); strcpy(line,stra);              /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
             }
         cutv(stra, strb,line,' '); weight[i]=(double)(atoi(strb)); strcpy(line,stra);          } /* end if mle */
         for (j=ncovcol;j>=1;j--){        }
           cutv(stra, strb,line,' '); covar[j][i]=(double)(atoi(strb)); strcpy(line,stra);      } /* end wave */
         }    }
         num[i]=atol(stra);    jmean=sum/k;
            printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
         /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){    fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
           printf("%d %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/   }
   
         i=i+1;  /*********** Tricode ****************************/
       }  void tricode(int *Tvar, int **nbcode, int imx, int *Ndum)
     }  {
     /* printf("ii=%d", ij);    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
        scanf("%d",i);*/    /*      Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
   imx=i-1; /* Number of individuals */     * Boring subroutine which should only output nbcode[Tvar[j]][k]
      * Tvar[5] in V2+V1+V3*age+V2*V4 is 2 (V2)
   /* for (i=1; i<=imx; i++){     * nbcode[Tvar[j]][1]= 
     if ((s[1][i]==3) && (s[2][i]==2)) s[2][i]=3;    */
     if ((s[2][i]==3) && (s[3][i]==2)) s[3][i]=3;  
     if ((s[3][i]==3) && (s[4][i]==2)) s[4][i]=3;    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
     }*/    int modmaxcovj=0; /* Modality max of covariates j */
    /*  for (i=1; i<=imx; i++){    int cptcode=0; /* Modality max of covariates j */
      if (s[4][i]==9)  s[4][i]=-1;    int modmincovj=0; /* Modality min of covariates j */
      printf("%d %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]), (weight[i]), (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i]));}*/  
    
      cptcoveff=0; 
   /* Calculation of the number of parameter from char model*/   
   Tvar=ivector(1,15); /* stores the number n of the covariates in Vm+Vn at 1 and m at 2 */    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
   Tprod=ivector(1,15);  
   Tvaraff=ivector(1,15);    /* Loop on covariates without age and products */
   Tvard=imatrix(1,15,1,2);    for (j=1; j<=(cptcovs); j++) { /* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only */
   Tage=ivector(1,15);            for (k=-1; k < maxncov; k++) Ndum[k]=0;
          for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the 
   if (strlen(model) >1){                                 modality of this covariate Vj*/ 
     j=0, j1=0, k1=1, k2=1;        ij=(int)(covar[Tvar[j]][i]); /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
     j=nbocc(model,'+');                                      * If product of Vn*Vm, still boolean *:
     j1=nbocc(model,'*');                                      * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
     cptcovn=j+1;                                      * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
     cptcovprod=j1;        /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                                            modality of the nth covariate of individual i. */
     strcpy(modelsav,model);        if (ij > modmaxcovj)
     if ((strcmp(model,"age")==0) || (strcmp(model,"age*age")==0)){          modmaxcovj=ij; 
       printf("Error. Non available option model=%s ",model);        else if (ij < modmincovj) 
       fprintf(ficlog,"Error. Non available option model=%s ",model);          modmincovj=ij; 
       goto end;        if ((ij < -1) && (ij > NCOVMAX)){
     }          printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
              exit(1);
     for(i=(j+1); i>=1;i--){        }else
       cutv(stra,strb,modelsav,'+'); /* keeps in strb after the last + */        Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
       if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyze it */        /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
       /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/        /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
       /*scanf("%d",i);*/        /* getting the maximum value of the modality of the covariate
       if (strchr(strb,'*')) {  /* Model includes a product */           (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
         cutv(strd,strc,strb,'*'); /* strd*strc  Vm*Vn (if not *age)*/           female is 1, then modmaxcovj=1.*/
         if (strcmp(strc,"age")==0) { /* Vn*age */      } /* end for loop on individuals i */
           cptcovprod--;      printf(" Minimal and maximal values of %d th covariate V%d: min=%d max=%d \n", j, Tvar[j], modmincovj, modmaxcovj);
           cutv(strb,stre,strd,'V');      fprintf(ficlog," Minimal and maximal values of %d th covariate V%d: min=%d max=%d \n", j, Tvar[j], modmincovj, modmaxcovj);
           Tvar[i]=atoi(stre); /* computes n in Vn and stores in Tvar*/      cptcode=modmaxcovj;
           cptcovage++;      /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
             Tage[cptcovage]=i;     /*for (i=0; i<=cptcode; i++) {*/
             /*printf("stre=%s ", stre);*/      for (k=modmincovj;  k<=modmaxcovj; k++) { /* k=-1 ? 0 and 1*//* For each value k of the modality of model-cov j */
         }        printf("Frequencies of covariates %d ie V%d with value %d: %d\n", j, Tvar[j], k, Ndum[k]);
         else if (strcmp(strd,"age")==0) { /* or age*Vn */        fprintf(ficlog, "Frequencies of covariates %d ie V%d with value %d: %d\n", j, Tvar[j], k, Ndum[k]);
           cptcovprod--;        if( Ndum[k] != 0 ){ /* Counts if nobody answered modality k ie empty modality, we skip it and reorder */
           cutv(strb,stre,strc,'V');          if( k != -1){
           Tvar[i]=atoi(stre);            ncodemax[j]++;  /* ncodemax[j]= Number of modalities of the j th
           cptcovage++;                               covariate for which somebody answered excluding 
           Tage[cptcovage]=i;                               undefined. Usually 2: 0 and 1. */
         }          }
         else {  /* Age is not in the model */          ncodemaxwundef[j]++; /* ncodemax[j]= Number of modalities of the j th
           cutv(strb,stre,strc,'V'); /* strc= Vn, stre is n*/                               covariate for which somebody answered including 
           Tvar[i]=ncovcol+k1;                               undefined. Usually 3: -1, 0 and 1. */
           cutv(strb,strc,strd,'V'); /* strd was Vm, strc is m */        }
           Tprod[k1]=i;        /* In fact  ncodemax[j]=2 (dichotom. variables only) but it could be more for
           Tvard[k1][1]=atoi(strc); /* m*/           historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
           Tvard[k1][2]=atoi(stre); /* n */      } /* Ndum[-1] number of undefined modalities */
           Tvar[cptcovn+k2]=Tvard[k1][1];  
           Tvar[cptcovn+k2+1]=Tvard[k1][2];      /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
           for (k=1; k<=lastobs;k++)      /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. 
             covar[ncovcol+k1][k]=covar[atoi(stre)][k]*covar[atoi(strc)][k];         If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125;
           k1++;         modmincovj=3; modmaxcovj = 7;
           k2=k2+2;         There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3;
         }         which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10;
       }         defining two dummy variables: variables V1_1 and V1_2.
       else { /* no more sum */         nbcode[Tvar[j]][ij]=k;
         /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/         nbcode[Tvar[j]][1]=0;
        /*  scanf("%d",i);*/         nbcode[Tvar[j]][2]=1;
       cutv(strd,strc,strb,'V');         nbcode[Tvar[j]][3]=2;
       Tvar[i]=atoi(strc);         To be continued (not working yet).
       }      */
       strcpy(modelsav,stra);        ij=0; /* ij is similar to i but can jump over null modalities */
       /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);      for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
         scanf("%d",i);*/          if (Ndum[i] == 0) { /* If nobody responded to this modality k */
     } /* end of loop + */            break;
   } /* end model */          }
            ij++;
   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);          nbcode[Tvar[j]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality.*/
   printf("cptcovprod=%d ", cptcovprod);          cptcode = ij; /* New max modality for covar j */
   fprintf(ficlog,"cptcovprod=%d ", cptcovprod);      } /* end of loop on modality i=-1 to 1 or more */
   scanf("%d ",i);*/        
     fclose(fic);      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
       /*  /\*recode from 0 *\/ */
     /*  if(mle==1){*/      /*                               k is a modality. If we have model=V1+V1*sex  */
     if (weightopt != 1) { /* Maximisation without weights*/      /*                               then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
       for(i=1;i<=n;i++) weight[i]=1.0;      /*                            But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
     }      /*  } */
     /*-calculation of age at interview from date of interview and age at death -*/      /*  /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
     agev=matrix(1,maxwav,1,imx);      /*  if (ij > ncodemax[j]) { */
       /*    printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
     for (i=1; i<=imx; i++) {      /*    fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
       for(m=2; (m<= maxwav); m++) {      /*    break; */
        if ((mint[m][i]== 99) && (s[m][i] <= nlstate)){      /*  } */
          anint[m][i]=9999;      /*   }  /\* end of loop on modality k *\/ */
          s[m][i]=-1;    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
        }    
      if(moisdc[i]==99 && andc[i]==9999 & s[m][i]>nlstate) s[m][i]=-1;   for (k=-1; k< maxncov; k++) Ndum[k]=0; 
       }    
     }    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
     for (i=1; i<=imx; i++)  {     ij=Tvar[i]; /* Tvar might be -1 if status was unknown */ 
       agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);     Ndum[ij]++; /* Might be supersed V1 + V1*age */
       for(m=1; (m<= maxwav); m++){   } 
         if(s[m][i] >0){  
           if (s[m][i] >= nlstate+1) {   ij=0;
             if(agedc[i]>0)   for (i=0; i<=  maxncov-1; i++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
               if(moisdc[i]!=99 && andc[i]!=9999)     /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                 agev[m][i]=agedc[i];     if((Ndum[i]!=0) && (i<=ncovcol)){
             /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/       ij++;
            else {       /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
               if (andc[i]!=9999){       Tvaraff[ij]=i; /*For printing (unclear) */
               printf("Warning negative age at death: %d line:%d\n",num[i],i);     }else{
               fprintf(ficlog,"Warning negative age at death: %d line:%d\n",num[i],i);         /* Tvaraff[ij]=0; */
               agev[m][i]=-1;     }
               }   }
             }   /* ij--; */
           }   cptcoveff=ij; /*Number of total covariates*/
           else if(s[m][i] !=9){ /* Should no more exist */  
             agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);  }
             if(mint[m][i]==99 || anint[m][i]==9999)  
               agev[m][i]=1;  
             else if(agev[m][i] <agemin){  /*********** Health Expectancies ****************/
               agemin=agev[m][i];  
               /*printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], agemin);*/  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[] )
             }  
             else if(agev[m][i] >agemax){  {
               agemax=agev[m][i];    /* Health expectancies, no variances */
              /* printf(" anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.0f\n",m,i,anint[m][i], i,annais[i], agemax);*/    int i, j, nhstepm, hstepm, h, nstepm;
             }    int nhstepma, nstepma; /* Decreasing with age */
             /*agev[m][i]=anint[m][i]-annais[i];*/    double age, agelim, hf;
             /*   agev[m][i] = age[i]+2*m;*/    double ***p3mat;
           }    double eip;
           else { /* =9 */  
             agev[m][i]=1;    pstamp(ficreseij);
             s[m][i]=-1;    fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
           }    fprintf(ficreseij,"# Age");
         }    for(i=1; i<=nlstate;i++){
         else /*= 0 Unknown */      for(j=1; j<=nlstate;j++){
           agev[m][i]=1;        fprintf(ficreseij," e%1d%1d ",i,j);
       }      }
          fprintf(ficreseij," e%1d. ",i);
     }    }
     for (i=1; i<=imx; i++)  {    fprintf(ficreseij,"\n");
       for(m=1; (m<= maxwav); m++){  
         if (s[m][i] > (nlstate+ndeath)) {    
           printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);      if(estepm < stepm){
           fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);        printf ("Problem %d lower than %d\n",estepm, stepm);
           goto end;    }
         }    else  hstepm=estepm;   
       }    /* We compute the life expectancy from trapezoids spaced every estepm months
     }     * This is mainly to measure the difference between two models: for example
      * if stepm=24 months pijx are given only every 2 years and by summing them
 printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, agemin, agemax);     * we are calculating an estimate of the Life Expectancy assuming a linear 
  fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, agemin, agemax);     * progression in between and thus overestimating or underestimating according
      * to the curvature of the survival function. If, for the same date, we 
     free_vector(severity,1,maxwav);     * estimate the model with stepm=1 month, we can keep estepm to 24 months
     free_imatrix(outcome,1,maxwav+1,1,n);     * to compare the new estimate of Life expectancy with the same linear 
     free_vector(moisnais,1,n);     * hypothesis. A more precise result, taking into account a more precise
     free_vector(annais,1,n);     * curvature will be obtained if estepm is as small as stepm. */
     /* free_matrix(mint,1,maxwav,1,n);  
        free_matrix(anint,1,maxwav,1,n);*/    /* For example we decided to compute the life expectancy with the smallest unit */
     free_vector(moisdc,1,n);    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
     free_vector(andc,1,n);       nhstepm is the number of hstepm from age to agelim 
        nstepm is the number of stepm from age to agelin. 
           Look at hpijx to understand the reason of that which relies in memory size
     wav=ivector(1,imx);       and note for a fixed period like estepm months */
     dh=imatrix(1,lastpass-firstpass+1,1,imx);    /* We decided (b) to get a life expectancy respecting the most precise curvature of the
     mw=imatrix(1,lastpass-firstpass+1,1,imx);       survival function given by stepm (the optimization length). Unfortunately it
           means that if the survival funtion is printed only each two years of age and if
     /* Concatenates waves */       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
       concatwav(wav, dh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);       results. So we changed our mind and took the option of the best precision.
     */
     hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
       Tcode=ivector(1,100);  
       nbcode=imatrix(0,NCOVMAX,0,NCOVMAX);    agelim=AGESUP;
       ncodemax[1]=1;    /* If stepm=6 months */
       if (cptcovn > 0) tricode(Tvar,nbcode,imx);      /* Computed by stepm unit matrices, product of hstepm matrices, stored
               in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
    codtab=imatrix(1,100,1,10);      
    h=0;  /* nhstepm age range expressed in number of stepm */
    m=pow(2,cptcoveff);    nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
      /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
    for(k=1;k<=cptcoveff; k++){    /* if (stepm >= YEARM) hstepm=1;*/
      for(i=1; i <=(m/pow(2,k));i++){    nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
        for(j=1; j <= ncodemax[k]; j++){    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
          for(cpt=1; cpt <=(m/pow(2,cptcoveff+1-k)); cpt++){  
            h++;    for (age=bage; age<=fage; age ++){ 
            if (h>m) h=1;codtab[h][k]=j;codtab[h][Tvar[k]]=j;      nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
            /*  printf("h=%d k=%d j=%d codtab[h][k]=%d tvar[k]=%d \n",h, k,j,codtab[h][k],Tvar[k]);*/      /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
          }      /* if (stepm >= YEARM) hstepm=1;*/
        }      nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
      }  
    }      /* If stepm=6 months */
    /* printf("codtab[1][2]=%d codtab[2][2]=%d",codtab[1][2],codtab[2][2]);      /* Computed by stepm unit matrices, product of hstepma matrices, stored
       codtab[1][2]=1;codtab[2][2]=2; */         in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
    /* for(i=1; i <=m ;i++){      
       for(k=1; k <=cptcovn; k++){      hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij);  
       printf("i=%d k=%d %d %d ",i,k,codtab[i][k], cptcoveff);      
       }      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
       printf("\n");      
       }      printf("%d|",(int)age);fflush(stdout);
       scanf("%d",i);*/      fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
          
    /* Calculates basic frequencies. Computes observed prevalence at single age      /* Computing expectancies */
        and prints on file fileres'p'. */      for(i=1; i<=nlstate;i++)
         for(j=1; j<=nlstate;j++)
              for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
     pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */            
     oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */            /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
     newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */  
     savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */          }
     oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */  
            fprintf(ficreseij,"%3.0f",age );
     /* For Powell, parameters are in a vector p[] starting at p[1]      for(i=1; i<=nlstate;i++){
        so we point p on param[1][1] so that p[1] maps on param[1][1][1] */        eip=0;
     p=param[1][1]; /* *(*(*(param +1)+1)+0) */        for(j=1; j<=nlstate;j++){
           eip +=eij[i][j][(int)age];
     if(mle==1){          fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
     mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);        }
     }        fprintf(ficreseij,"%9.4f", eip );
          }
     /*--------- results files --------------*/      fprintf(ficreseij,"\n");
     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate, ndeath, maxwav, weightopt,model);      
      }
     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
    jk=1;    printf("\n");
    fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");    fprintf(ficlog,"\n");
    printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");    
    fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");  }
    for(i=1,jk=1; i <=nlstate; i++){  
      for(k=1; k <=(nlstate+ndeath); k++){  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[] )
        if (k != i)  
          {  {
            printf("%d%d ",i,k);    /* Covariances of health expectancies eij and of total life expectancies according
            fprintf(ficlog,"%d%d ",i,k);     to initial status i, ei. .
            fprintf(ficres,"%1d%1d ",i,k);    */
            for(j=1; j <=ncovmodel; j++){    int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
              printf("%f ",p[jk]);    int nhstepma, nstepma; /* Decreasing with age */
              fprintf(ficlog,"%f ",p[jk]);    double age, agelim, hf;
              fprintf(ficres,"%f ",p[jk]);    double ***p3matp, ***p3matm, ***varhe;
              jk++;    double **dnewm,**doldm;
            }    double *xp, *xm;
            printf("\n");    double **gp, **gm;
            fprintf(ficlog,"\n");    double ***gradg, ***trgradg;
            fprintf(ficres,"\n");    int theta;
          }  
      }    double eip, vip;
    }  
    if(mle==1){    varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
      /* Computing hessian and covariance matrix */    xp=vector(1,npar);
      ftolhess=ftol; /* Usually correct */    xm=vector(1,npar);
      hesscov(matcov, p, npar, delti, ftolhess, func);    dnewm=matrix(1,nlstate*nlstate,1,npar);
    }    doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
    fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");    
    printf("# Scales (for hessian or gradient estimation)\n");    pstamp(ficresstdeij);
    fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");    fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
    for(i=1,jk=1; i <=nlstate; i++){    fprintf(ficresstdeij,"# Age");
      for(j=1; j <=nlstate+ndeath; j++){    for(i=1; i<=nlstate;i++){
        if (j!=i) {      for(j=1; j<=nlstate;j++)
          fprintf(ficres,"%1d%1d",i,j);        fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
          printf("%1d%1d",i,j);      fprintf(ficresstdeij," e%1d. ",i);
          fprintf(ficlog,"%1d%1d",i,j);    }
          for(k=1; k<=ncovmodel;k++){    fprintf(ficresstdeij,"\n");
            printf(" %.5e",delti[jk]);  
            fprintf(ficlog," %.5e",delti[jk]);    pstamp(ficrescveij);
            fprintf(ficres," %.5e",delti[jk]);    fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
            jk++;    fprintf(ficrescveij,"# Age");
          }    for(i=1; i<=nlstate;i++)
          printf("\n");      for(j=1; j<=nlstate;j++){
          fprintf(ficlog,"\n");        cptj= (j-1)*nlstate+i;
          fprintf(ficres,"\n");        for(i2=1; i2<=nlstate;i2++)
        }          for(j2=1; j2<=nlstate;j2++){
      }            cptj2= (j2-1)*nlstate+i2;
    }            if(cptj2 <= cptj)
                  fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
    k=1;          }
    fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");      }
    if(mle==1)    fprintf(ficrescveij,"\n");
      printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");    
    fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");    if(estepm < stepm){
    for(i=1;i<=npar;i++){      printf ("Problem %d lower than %d\n",estepm, stepm);
      /*  if (k>nlstate) k=1;    }
          i1=(i-1)/(ncovmodel*nlstate)+1;    else  hstepm=estepm;   
          fprintf(ficres,"%s%d%d",alph[k],i1,tab[i]);    /* We compute the life expectancy from trapezoids spaced every estepm months
          printf("%s%d%d",alph[k],i1,tab[i]);*/     * This is mainly to measure the difference between two models: for example
      fprintf(ficres,"%3d",i);     * if stepm=24 months pijx are given only every 2 years and by summing them
      if(mle==1)     * we are calculating an estimate of the Life Expectancy assuming a linear 
        printf("%3d",i);     * progression in between and thus overestimating or underestimating according
      fprintf(ficlog,"%3d",i);     * to the curvature of the survival function. If, for the same date, we 
      for(j=1; j<=i;j++){     * estimate the model with stepm=1 month, we can keep estepm to 24 months
        fprintf(ficres," %.5e",matcov[i][j]);     * to compare the new estimate of Life expectancy with the same linear 
        if(mle==1)     * hypothesis. A more precise result, taking into account a more precise
          printf(" %.5e",matcov[i][j]);     * curvature will be obtained if estepm is as small as stepm. */
        fprintf(ficlog," %.5e",matcov[i][j]);  
      }    /* For example we decided to compute the life expectancy with the smallest unit */
      fprintf(ficres,"\n");    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
      if(mle==1)       nhstepm is the number of hstepm from age to agelim 
        printf("\n");       nstepm is the number of stepm from age to agelin. 
      fprintf(ficlog,"\n");       Look at hpijx to understand the reason of that which relies in memory size
      k++;       and note for a fixed period like estepm months */
    }    /* We decided (b) to get a life expectancy respecting the most precise curvature of the
           survival function given by stepm (the optimization length). Unfortunately it
    while((c=getc(ficpar))=='#' && c!= EOF){       means that if the survival funtion is printed only each two years of age and if
      ungetc(c,ficpar);       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
      fgets(line, MAXLINE, ficpar);       results. So we changed our mind and took the option of the best precision.
      puts(line);    */
      fputs(line,ficparo);    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
    }  
    ungetc(c,ficpar);    /* If stepm=6 months */
    estepm=0;    /* nhstepm age range expressed in number of stepm */
    fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm);    agelim=AGESUP;
    if (estepm==0 || estepm < stepm) estepm=stepm;    nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
    if (fage <= 2) {    /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
      bage = ageminpar;    /* if (stepm >= YEARM) hstepm=1;*/
      fage = agemaxpar;    nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
    }    
        p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
    fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");    p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
    fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d\n",ageminpar,agemaxpar,bage,fage, estepm);    gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
    fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d\n",ageminpar,agemaxpar,bage,fage, estepm);    trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
        gp=matrix(0,nhstepm,1,nlstate*nlstate);
    while((c=getc(ficpar))=='#' && c!= EOF){    gm=matrix(0,nhstepm,1,nlstate*nlstate);
      ungetc(c,ficpar);  
      fgets(line, MAXLINE, ficpar);    for (age=bage; age<=fage; age ++){ 
      puts(line);      nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
      fputs(line,ficparo);      /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
    }      /* if (stepm >= YEARM) hstepm=1;*/
    ungetc(c,ficpar);      nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
    
    fscanf(ficpar,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2);      /* If stepm=6 months */
    fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);      /* Computed by stepm unit matrices, product of hstepma matrices, stored
    fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);         in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
          
    while((c=getc(ficpar))=='#' && c!= EOF){      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
      ungetc(c,ficpar);  
      fgets(line, MAXLINE, ficpar);      /* Computing  Variances of health expectancies */
      puts(line);      /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
      fputs(line,ficparo);         decrease memory allocation */
    }      for(theta=1; theta <=npar; theta++){
    ungetc(c,ficpar);        for(i=1; i<=npar; i++){ 
            xp[i] = x[i] + (i==theta ?delti[theta]:0);
           xm[i] = x[i] - (i==theta ?delti[theta]:0);
    dateprev1=anprev1+mprev1/12.+jprev1/365.;        }
    dateprev2=anprev2+mprev2/12.+jprev2/365.;        hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij);  
         hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij);  
   fscanf(ficpar,"pop_based=%d\n",&popbased);    
   fprintf(ficparo,"pop_based=%d\n",popbased);          for(j=1; j<= nlstate; j++){
   fprintf(ficres,"pop_based=%d\n",popbased);            for(i=1; i<=nlstate; i++){
              for(h=0; h<=nhstepm-1; h++){
   while((c=getc(ficpar))=='#' && c!= EOF){              gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
     ungetc(c,ficpar);              gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
     fgets(line, MAXLINE, ficpar);            }
     puts(line);          }
     fputs(line,ficparo);        }
   }       
   ungetc(c,ficpar);        for(ij=1; ij<= nlstate*nlstate; ij++)
           for(h=0; h<=nhstepm-1; h++){
   fscanf(ficpar,"starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mov_average=%d\n",&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilav);            gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
 fprintf(ficparo,"starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mov_average=%d\n",jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilav);          }
 fprintf(ficres,"starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mov_average=%d\n",jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilav);      }/* End theta */
       
       
 while((c=getc(ficpar))=='#' && c!= EOF){      for(h=0; h<=nhstepm-1; h++)
     ungetc(c,ficpar);        for(j=1; j<=nlstate*nlstate;j++)
     fgets(line, MAXLINE, ficpar);          for(theta=1; theta <=npar; theta++)
     puts(line);            trgradg[h][j][theta]=gradg[h][theta][j];
     fputs(line,ficparo);      
   }  
   ungetc(c,ficpar);       for(ij=1;ij<=nlstate*nlstate;ij++)
         for(ji=1;ji<=nlstate*nlstate;ji++)
   fscanf(ficpar,"popforecast=%d popfile=%s popfiledate=%lf/%lf/%lf last-popfiledate=%lf/%lf/%lf\n",&popforecast,popfile,&jpyram,&mpyram,&anpyram,&jpyram1,&mpyram1,&anpyram1);          varhe[ij][ji][(int)age] =0.;
   fprintf(ficparo,"popforecast=%d popfile=%s popfiledate=%.lf/%.lf/%.lf last-popfiledate=%.lf/%.lf/%.lf\n",popforecast,popfile,jpyram,mpyram,anpyram,jpyram1,mpyram1,anpyram1);  
   fprintf(ficres,"popforecast=%d popfile=%s popfiledate=%.lf/%.lf/%.lf last-popfiledate=%.lf/%.lf/%.lf\n",popforecast,popfile,jpyram,mpyram,anpyram,jpyram1,mpyram1,anpyram1);       printf("%d|",(int)age);fflush(stdout);
        fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
  freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax,mint,anint,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);       for(h=0;h<=nhstepm-1;h++){
         for(k=0;k<=nhstepm-1;k++){
 /*------------ gnuplot -------------*/          matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
   strcpy(optionfilegnuplot,optionfilefiname);          matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
   strcat(optionfilegnuplot,".gp");          for(ij=1;ij<=nlstate*nlstate;ij++)
   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {            for(ji=1;ji<=nlstate*nlstate;ji++)
     printf("Problem with file %s",optionfilegnuplot);              varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
   }        }
   fclose(ficgp);      }
  printinggnuplot(fileres, ageminpar,agemaxpar,fage, pathc,p);  
 /*--------- index.htm --------*/      /* Computing expectancies */
       hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij);  
   strcpy(optionfilehtm,optionfile);      for(i=1; i<=nlstate;i++)
   strcat(optionfilehtm,".htm");        for(j=1; j<=nlstate;j++)
   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {          for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
     printf("Problem with %s \n",optionfilehtm), exit(0);            eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
   }            
             /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
   fprintf(fichtm,"<body> <font size=\"2\">%s </font> <hr size=\"2\" color=\"#EC5E5E\"> \n  
 Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=%s<br>\n          }
 \n  
 Total number of observations=%d <br>\n      fprintf(ficresstdeij,"%3.0f",age );
 Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n      for(i=1; i<=nlstate;i++){
 <hr  size=\"2\" color=\"#EC5E5E\">        eip=0.;
  <ul><li><h4>Parameter files</h4>\n        vip=0.;
  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n        for(j=1; j<=nlstate;j++){
  - Log file of the run: <a href=\"%s\">%s</a><br>\n          eip += eij[i][j][(int)age];
  - Gnuplot file name: <a href=\"%s\">%s</a></ul>\n",version,title,datafile,firstpass,lastpass,stepm, weightopt,model,imx,jmin,jmax,jmean,fileres,fileres,filelog,filelog,optionfilegnuplot,optionfilegnuplot);          for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
   fclose(fichtm);            vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
           fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
  printinghtml(fileres,title,datafile, firstpass, lastpass, stepm, weightopt,model,imx,jmin,jmax,jmean,rfileres,popforecast,estepm,jprev1,mprev1,anprev1,jprev2,mprev2,anprev2);        }
          fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
 /*------------ free_vector  -------------*/      }
  chdir(path);      fprintf(ficresstdeij,"\n");
    
  free_ivector(wav,1,imx);      fprintf(ficrescveij,"%3.0f",age );
  free_imatrix(dh,1,lastpass-firstpass+1,1,imx);      for(i=1; i<=nlstate;i++)
  free_imatrix(mw,1,lastpass-firstpass+1,1,imx);          for(j=1; j<=nlstate;j++){
  free_ivector(num,1,n);          cptj= (j-1)*nlstate+i;
  free_vector(agedc,1,n);          for(i2=1; i2<=nlstate;i2++)
  /*free_matrix(covar,1,NCOVMAX,1,n);*/            for(j2=1; j2<=nlstate;j2++){
  fclose(ficparo);              cptj2= (j2-1)*nlstate+i2;
  fclose(ficres);              if(cptj2 <= cptj)
                 fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
             }
   /*--------------- Prevalence limit --------------*/        }
        fprintf(ficrescveij,"\n");
   strcpy(filerespl,"pl");     
   strcat(filerespl,fileres);    }
   if((ficrespl=fopen(filerespl,"w"))==NULL) {    free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
     printf("Problem with Prev limit resultfile: %s\n", filerespl);goto end;    free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
     fprintf(ficlog,"Problem with Prev limit resultfile: %s\n", filerespl);goto end;    free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
   }    free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
   printf("Computing prevalence limit: result on file '%s' \n", filerespl);    free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
   fprintf(ficlog,"Computing prevalence limit: result on file '%s' \n", filerespl);    free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
   fprintf(ficrespl,"#Prevalence limit\n");    printf("\n");
   fprintf(ficrespl,"#Age ");    fprintf(ficlog,"\n");
   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);  
   fprintf(ficrespl,"\n");    free_vector(xm,1,npar);
      free_vector(xp,1,npar);
   prlim=matrix(1,nlstate,1,nlstate);    free_matrix(dnewm,1,nlstate*nlstate,1,npar);
   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */    free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */    free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */  }
   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */  
   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */  /************ Variance ******************/
   k=0;  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[])
   agebase=ageminpar;  {
   agelim=agemaxpar;    /* Variance of health expectancies */
   ftolpl=1.e-10;    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
   i1=cptcoveff;    /* double **newm;*/
   if (cptcovn < 1){i1=1;}    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
     
   for(cptcov=1;cptcov<=i1;cptcov++){    int movingaverage();
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){    double **dnewm,**doldm;
         k=k+1;    double **dnewmp,**doldmp;
         /*printf("cptcov=%d cptcod=%d codtab=%d nbcode=%d\n",cptcov, cptcod,Tcode[cptcode],codtab[cptcod][cptcov]);*/    int i, j, nhstepm, hstepm, h, nstepm ;
         fprintf(ficrespl,"\n#******");    int k;
         printf("\n#******");    double *xp;
         fprintf(ficlog,"\n#******");    double **gp, **gm;  /* for var eij */
         for(j=1;j<=cptcoveff;j++) {    double ***gradg, ***trgradg; /*for var eij */
           fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);    double **gradgp, **trgradgp; /* for var p point j */
           printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);    double *gpp, *gmp; /* for var p point j */
           fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
         }    double ***p3mat;
         fprintf(ficrespl,"******\n");    double age,agelim, hf;
         printf("******\n");    double ***mobaverage;
         fprintf(ficlog,"******\n");    int theta;
            char digit[4];
         for (age=agebase; age<=agelim; age++){    char digitp[25];
           prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);  
           fprintf(ficrespl,"%.0f",age );    char fileresprobmorprev[FILENAMELENGTH];
           for(i=1; i<=nlstate;i++)  
           fprintf(ficrespl," %.5f", prlim[i][i]);    if(popbased==1){
           fprintf(ficrespl,"\n");      if(mobilav!=0)
         }        strcpy(digitp,"-POPULBASED-MOBILAV_");
       }      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
     }    }
   fclose(ficrespl);    else 
       strcpy(digitp,"-STABLBASED_");
   /*------------- h Pij x at various ages ------------*/  
      if (mobilav!=0) {
   strcpy(filerespij,"pij");  strcat(filerespij,fileres);      mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
   if((ficrespij=fopen(filerespij,"w"))==NULL) {      if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){
     printf("Problem with Pij resultfile: %s\n", filerespij);goto end;        fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
     fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij);goto end;        printf(" Error in movingaverage mobilav=%d\n",mobilav);
   }      }
   printf("Computing pij: result on file '%s' \n", filerespij);    }
   fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);  
      strcpy(fileresprobmorprev,"PRMORPREV-"); 
   stepsize=(int) (stepm+YEARM-1)/YEARM;    sprintf(digit,"%-d",ij);
   /*if (stepm<=24) stepsize=2;*/    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
     strcat(fileresprobmorprev,digit); /* Tvar to be done */
   agelim=AGESUP;    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
   hstepm=stepsize*YEARM; /* Every year of age */    strcat(fileresprobmorprev,fileres);
   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
       printf("Problem with resultfile: %s\n", fileresprobmorprev);
   /* hstepm=1;   aff par mois*/      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
     }
   k=0;    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
   for(cptcov=1;cptcov<=i1;cptcov++){   
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
       k=k+1;    pstamp(ficresprobmorprev);
         fprintf(ficrespij,"\n#****** ");    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
         for(j=1;j<=cptcoveff;j++)    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
           fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
         fprintf(ficrespij,"******\n");      fprintf(ficresprobmorprev," p.%-d SE",j);
              for(i=1; i<=nlstate;i++)
         for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
           nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */    }  
           nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */    fprintf(ficresprobmorprev,"\n");
     fprintf(ficgp,"\n# Routine varevsij");
           /*      nhstepm=nhstepm*YEARM; aff par mois*/    fprintf(ficgp,"\nunset title \n");
   /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
           p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
           oldm=oldms;savm=savms;    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
           hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);    /*   } */
           fprintf(ficrespij,"# Age");    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
           for(i=1; i<=nlstate;i++)    pstamp(ficresvij);
             for(j=1; j<=nlstate+ndeath;j++)    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
               fprintf(ficrespij," %1d-%1d",i,j);    if(popbased==1)
           fprintf(ficrespij,"\n");      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
            for (h=0; h<=nhstepm; h++){    else
             fprintf(ficrespij,"%d %f %f",k,agedeb, agedeb+ h*hstepm/YEARM*stepm );      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
             for(i=1; i<=nlstate;i++)    fprintf(ficresvij,"# Age");
               for(j=1; j<=nlstate+ndeath;j++)    for(i=1; i<=nlstate;i++)
                 fprintf(ficrespij," %.5f", p3mat[i][j][h]);      for(j=1; j<=nlstate;j++)
             fprintf(ficrespij,"\n");        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
              }    fprintf(ficresvij,"\n");
           free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);  
           fprintf(ficrespij,"\n");    xp=vector(1,npar);
         }    dnewm=matrix(1,nlstate,1,npar);
     }    doldm=matrix(1,nlstate,1,nlstate);
   }    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
     doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
   varprob(optionfilefiname, matcov, p, delti, nlstate, (int) bage, (int) fage,k,Tvar,nbcode, ncodemax);  
     gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
   fclose(ficrespij);    gpp=vector(nlstate+1,nlstate+ndeath);
     gmp=vector(nlstate+1,nlstate+ndeath);
     trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
   /*---------- Forecasting ------------------*/    
   if((stepm == 1) && (strcmp(model,".")==0)){    if(estepm < stepm){
     prevforecast(fileres, anproj1,mproj1,jproj1, agemin,agemax, dateprev1, dateprev2,mobilav, agedeb, fage, popforecast, popfile, anproj2,p, i1);      printf ("Problem %d lower than %d\n",estepm, stepm);
     if (popforecast==1) populforecast(fileres, anpyram,mpyram,jpyram, agemin,agemax, dateprev1, dateprev2,mobilav, agedeb, fage, popforecast, popfile, anpyram1,p, i1);    }
   }    else  hstepm=estepm;   
   else{    /* For example we decided to compute the life expectancy with the smallest unit */
     erreur=108;    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
     printf("Warning %d!! You can only forecast the prevalences if the optimization\n  has been performed with stepm = 1 (month) instead of %d or model=. instead of '%s'\n", erreur, stepm, model);       nhstepm is the number of hstepm from age to agelim 
     fprintf(ficlog,"Warning %d!! You can only forecast the prevalences if the optimization\n  has been performed with stepm = 1 (month) instead of %d or model=. instead of '%s'\n", erreur, stepm, model);       nstepm is the number of stepm from age to agelin. 
   }       Look at function hpijx to understand why (it is linked to memory size questions) */
      /* We decided (b) to get a life expectancy respecting the most precise curvature of the
        survival function given by stepm (the optimization length). Unfortunately it
   /*---------- Health expectancies and variances ------------*/       means that if the survival funtion is printed every two years of age and if
        you sum them up and add 1 year (area under the trapezoids) you won't get the same 
   strcpy(filerest,"t");       results. So we changed our mind and took the option of the best precision.
   strcat(filerest,fileres);    */
   if((ficrest=fopen(filerest,"w"))==NULL) {    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
     printf("Problem with total LE resultfile: %s\n", filerest);goto end;    agelim = AGESUP;
     fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
   }      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
   printf("Computing Total LEs with variances: file '%s' \n", filerest);      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
   fprintf(ficlog,"Computing Total LEs with variances: file '%s' \n", filerest);      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
       gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
       gp=matrix(0,nhstepm,1,nlstate);
   strcpy(filerese,"e");      gm=matrix(0,nhstepm,1,nlstate);
   strcat(filerese,fileres);  
   if((ficreseij=fopen(filerese,"w"))==NULL) {  
     printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);      for(theta=1; theta <=npar; theta++){
     fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
   }          xp[i] = x[i] + (i==theta ?delti[theta]:0);
   printf("Computing Health Expectancies: result on file '%s' \n", filerese);        }
   fprintf(ficlog,"Computing Health Expectancies: result on file '%s' \n", filerese);        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);  
         prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);
   strcpy(fileresv,"v");  
   strcat(fileresv,fileres);        if (popbased==1) {
   if((ficresvij=fopen(fileresv,"w"))==NULL) {          if(mobilav ==0){
     printf("Problem with variance resultfile: %s\n", fileresv);exit(0);            for(i=1; i<=nlstate;i++)
     fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);              prlim[i][i]=probs[(int)age][i][ij];
   }          }else{ /* mobilav */ 
   printf("Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);            for(i=1; i<=nlstate;i++)
   fprintf(ficlog,"Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);              prlim[i][i]=mobaverage[(int)age][i][ij];
   calagedate=-1;          }
   prevalence(ageminpar, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax,mint,anint,dateprev1,dateprev2, calagedate);        }
     
   k=0;        for(j=1; j<= nlstate; j++){
   for(cptcov=1;cptcov<=i1;cptcov++){          for(h=0; h<=nhstepm; h++){
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){            for(i=1, gp[h][j]=0.;i<=nlstate;i++)
       k=k+1;              gp[h][j] += prlim[i][i]*p3mat[i][j][h];
       fprintf(ficrest,"\n#****** ");          }
       for(j=1;j<=cptcoveff;j++)        }
         fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);        /* This for computing probability of death (h=1 means
       fprintf(ficrest,"******\n");           computed over hstepm matrices product = hstepm*stepm months) 
            as a weighted average of prlim.
       fprintf(ficreseij,"\n#****** ");        */
       for(j=1;j<=cptcoveff;j++)        for(j=nlstate+1;j<=nlstate+ndeath;j++){
         fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);          for(i=1,gpp[j]=0.; i<= nlstate; i++)
       fprintf(ficreseij,"******\n");            gpp[j] += prlim[i][i]*p3mat[i][j][1];
         }    
       fprintf(ficresvij,"\n#****** ");        /* end probability of death */
       for(j=1;j<=cptcoveff;j++)  
         fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
       fprintf(ficresvij,"******\n");          xp[i] = x[i] - (i==theta ?delti[theta]:0);
         hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);  
       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);
       oldm=oldms;savm=savms;   
       evsij(fileres, eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov);          if (popbased==1) {
            if(mobilav ==0){
       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);            for(i=1; i<=nlstate;i++)
       oldm=oldms;savm=savms;              prlim[i][i]=probs[(int)age][i][ij];
       varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k, estepm, cptcov,cptcod,0);          }else{ /* mobilav */ 
       if(popbased==1){            for(i=1; i<=nlstate;i++)
         varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k, estepm, cptcov,cptcod,popbased);              prlim[i][i]=mobaverage[(int)age][i][ij];
        }          }
         }
    
       fprintf(ficrest,"#Total LEs with variances: e.. (std) ");        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
       for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);          for(h=0; h<=nhstepm; h++){
       fprintf(ficrest,"\n");            for(i=1, gm[h][j]=0.;i<=nlstate;i++)
               gm[h][j] += prlim[i][i]*p3mat[i][j][h];
       epj=vector(1,nlstate+1);          }
       for(age=bage; age <=fage ;age++){        }
         prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);        /* This for computing probability of death (h=1 means
         if (popbased==1) {           computed over hstepm matrices product = hstepm*stepm months) 
           for(i=1; i<=nlstate;i++)           as a weighted average of prlim.
             prlim[i][i]=probs[(int)age][i][k];        */
         }        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                  for(i=1,gmp[j]=0.; i<= nlstate; i++)
         fprintf(ficrest," %4.0f",age);           gmp[j] += prlim[i][i]*p3mat[i][j][1];
         for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){        }    
           for(i=1, epj[j]=0.;i <=nlstate;i++) {        /* end probability of death */
             epj[j] += prlim[i][i]*eij[i][j][(int)age];  
             /*  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/        for(j=1; j<= nlstate; j++) /* vareij */
           }          for(h=0; h<=nhstepm; h++){
           epj[nlstate+1] +=epj[j];            gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
         }          }
   
         for(i=1, vepp=0.;i <=nlstate;i++)        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
           for(j=1;j <=nlstate;j++)          gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
             vepp += vareij[i][j][(int)age];        }
         fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));  
         for(j=1;j <=nlstate;j++){      } /* End theta */
           fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));  
         }      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
         fprintf(ficrest,"\n");  
       }      for(h=0; h<=nhstepm; h++) /* veij */
     }        for(j=1; j<=nlstate;j++)
   }          for(theta=1; theta <=npar; theta++)
 free_matrix(mint,1,maxwav,1,n);            trgradg[h][j][theta]=gradg[h][theta][j];
     free_matrix(anint,1,maxwav,1,n); free_imatrix(s,1,maxwav+1,1,n);  
     free_vector(weight,1,n);      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
   fclose(ficreseij);        for(theta=1; theta <=npar; theta++)
   fclose(ficresvij);          trgradgp[j][theta]=gradgp[theta][j];
   fclose(ficrest);    
   fclose(ficpar);  
   free_vector(epj,1,nlstate+1);      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
        for(i=1;i<=nlstate;i++)
   /*------- Variance limit prevalence------*/          for(j=1;j<=nlstate;j++)
           vareij[i][j][(int)age] =0.;
   strcpy(fileresvpl,"vpl");  
   strcat(fileresvpl,fileres);      for(h=0;h<=nhstepm;h++){
   if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {        for(k=0;k<=nhstepm;k++){
     printf("Problem with variance prev lim resultfile: %s\n", fileresvpl);          matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
     exit(0);          matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
   }          for(i=1;i<=nlstate;i++)
   printf("Computing Variance-covariance of Prevalence limit: file '%s' \n", fileresvpl);            for(j=1;j<=nlstate;j++)
               vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
   k=0;        }
   for(cptcov=1;cptcov<=i1;cptcov++){      }
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){    
       k=k+1;      /* pptj */
       fprintf(ficresvpl,"\n#****** ");      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
       for(j=1;j<=cptcoveff;j++)      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
         fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);      for(j=nlstate+1;j<=nlstate+ndeath;j++)
       fprintf(ficresvpl,"******\n");        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                varppt[j][i]=doldmp[j][i];
       varpl=matrix(1,nlstate,(int) bage, (int) fage);      /* end ppptj */
       oldm=oldms;savm=savms;      /*  x centered again */
      varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k);      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij);  
     }      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ij);
  }   
       if (popbased==1) {
   fclose(ficresvpl);        if(mobilav ==0){
           for(i=1; i<=nlstate;i++)
   /*---------- End : free ----------------*/            prlim[i][i]=probs[(int)age][i][ij];
   free_matrix(varpl,1,nlstate,(int) bage, (int)fage);        }else{ /* mobilav */ 
            for(i=1; i<=nlstate;i++)
   free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);            prlim[i][i]=mobaverage[(int)age][i][ij];
   free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);        }
        }
                 
   free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);      /* This for computing probability of death (h=1 means
   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);         computed over hstepm (estepm) matrices product = hstepm*stepm months) 
   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);         as a weighted average of prlim.
   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);      */
        for(j=nlstate+1;j<=nlstate+ndeath;j++){
   free_matrix(matcov,1,npar,1,npar);        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
   free_vector(delti,1,npar);          gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
   free_matrix(agev,1,maxwav,1,imx);      }    
   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);      /* end probability of death */
   
   fprintf(fichtm,"\n</body>");      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
   fclose(fichtm);      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
   fclose(ficgp);        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
          for(i=1; i<=nlstate;i++){
           fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
   if(erreur >0){        }
     printf("End of Imach with error or warning %d\n",erreur);      } 
     fprintf(ficlog,"End of Imach with error or warning %d\n",erreur);      fprintf(ficresprobmorprev,"\n");
   }else{  
    printf("End of Imach\n");      fprintf(ficresvij,"%.0f ",age );
    fprintf(ficlog,"End of Imach\n");      for(i=1; i<=nlstate;i++)
   }        for(j=1; j<=nlstate;j++){
   printf("See log file on %s\n",filelog);          fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
   fclose(ficlog);        }
   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */      fprintf(ficresvij,"\n");
        free_matrix(gp,0,nhstepm,1,nlstate);
   /* printf("Total time was %d Sec. %d uSec.\n", end_time.tv_sec -start_time.tv_sec, end_time.tv_usec -start_time.tv_usec);*/      free_matrix(gm,0,nhstepm,1,nlstate);
   /*printf("Total time was %d uSec.\n", total_usecs);*/      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
   /*------ End -----------*/      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     } /* End age */
  end:    free_vector(gpp,nlstate+1,nlstate+ndeath);
 #ifdef windows    free_vector(gmp,nlstate+1,nlstate+ndeath);
   /* chdir(pathcd);*/    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
 #endif    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
  /*system("wgnuplot graph.plt");*/    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
  /*system("../gp37mgw/wgnuplot graph.plt");*/    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
  /*system("cd ../gp37mgw");*/    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
  /* system("..\\gp37mgw\\wgnuplot graph.plt");*/    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
  strcpy(plotcmd,GNUPLOTPROGRAM);    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
  strcat(plotcmd," ");  /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
  strcat(plotcmd,optionfilegnuplot);  /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
  system(plotcmd);  /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
     fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
 #ifdef windows    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
   while (z[0] != 'q') {    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
     /* chdir(path); */    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
     printf("\nType e to edit output files, g to graph again, c to start again, and q for exiting: ");    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
     scanf("%s",z);    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
     if (z[0] == 'c') system("./imach");  */
     else if (z[0] == 'e') system(optionfilehtm);  /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
     else if (z[0] == 'g') system(plotcmd);    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
     else if (z[0] == 'q') exit(0);  
   }    free_vector(xp,1,npar);
 #endif    free_matrix(doldm,1,nlstate,1,nlstate);
 }    free_matrix(dnewm,1,nlstate,1,npar);
     free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
     free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
     free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
     if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     fclose(ficresprobmorprev);
     fflush(ficgp);
     fflush(fichtm); 
   }  /* end varevsij */
   
   /************ Variance of prevlim ******************/
   void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij, char strstart[])
   {
     /* Variance of prevalence limit */
     /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
   
     double **dnewm,**doldm;
     int i, j, nhstepm, hstepm;
     double *xp;
     double *gp, *gm;
     double **gradg, **trgradg;
     double age,agelim;
     int theta;
     
     pstamp(ficresvpl);
     fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
     fprintf(ficresvpl,"# Age");
     for(i=1; i<=nlstate;i++)
         fprintf(ficresvpl," %1d-%1d",i,i);
     fprintf(ficresvpl,"\n");
   
     xp=vector(1,npar);
     dnewm=matrix(1,nlstate,1,npar);
     doldm=matrix(1,nlstate,1,nlstate);
     
     hstepm=1*YEARM; /* Every year of age */
     hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
     agelim = AGESUP;
     for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
       nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
       if (stepm >= YEARM) hstepm=1;
       nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
       gradg=matrix(1,npar,1,nlstate);
       gp=vector(1,nlstate);
       gm=vector(1,nlstate);
   
       for(theta=1; theta <=npar; theta++){
         for(i=1; i<=npar; i++){ /* Computes gradient */
           xp[i] = x[i] + (i==theta ?delti[theta]:0);
         }
         prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);
         for(i=1;i<=nlstate;i++)
           gp[i] = prlim[i][i];
       
         for(i=1; i<=npar; i++) /* Computes gradient */
           xp[i] = x[i] - (i==theta ?delti[theta]:0);
         prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);
         for(i=1;i<=nlstate;i++)
           gm[i] = prlim[i][i];
   
         for(i=1;i<=nlstate;i++)
           gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
       } /* End theta */
   
       trgradg =matrix(1,nlstate,1,npar);
   
       for(j=1; j<=nlstate;j++)
         for(theta=1; theta <=npar; theta++)
           trgradg[j][theta]=gradg[theta][j];
   
       for(i=1;i<=nlstate;i++)
         varpl[i][(int)age] =0.;
       matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
       matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
       for(i=1;i<=nlstate;i++)
         varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
   
       fprintf(ficresvpl,"%.0f ",age );
       for(i=1; i<=nlstate;i++)
         fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
       fprintf(ficresvpl,"\n");
       free_vector(gp,1,nlstate);
       free_vector(gm,1,nlstate);
       free_matrix(gradg,1,npar,1,nlstate);
       free_matrix(trgradg,1,nlstate,1,npar);
     } /* End age */
   
     free_vector(xp,1,npar);
     free_matrix(doldm,1,nlstate,1,npar);
     free_matrix(dnewm,1,nlstate,1,nlstate);
   
   }
   
   /************ Variance of one-step probabilities  ******************/
   void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
   {
     int i, j=0,  k1, l1, tj;
     int k2, l2, j1,  z1;
     int k=0, l;
     int first=1, first1, first2;
     double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
     double **dnewm,**doldm;
     double *xp;
     double *gp, *gm;
     double **gradg, **trgradg;
     double **mu;
     double age, cov[NCOVMAX+1];
     double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
     int theta;
     char fileresprob[FILENAMELENGTH];
     char fileresprobcov[FILENAMELENGTH];
     char fileresprobcor[FILENAMELENGTH];
     double ***varpij;
   
     strcpy(fileresprob,"PROB_"); 
     strcat(fileresprob,fileres);
     if((ficresprob=fopen(fileresprob,"w"))==NULL) {
       printf("Problem with resultfile: %s\n", fileresprob);
       fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
     }
     strcpy(fileresprobcov,"PROBCOV_"); 
     strcat(fileresprobcov,fileres);
     if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
       printf("Problem with resultfile: %s\n", fileresprobcov);
       fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
     }
     strcpy(fileresprobcor,"PROBCOR_"); 
     strcat(fileresprobcor,fileres);
     if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
       printf("Problem with resultfile: %s\n", fileresprobcor);
       fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
     }
     printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
     fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
     printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
     fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
     printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
     fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
     pstamp(ficresprob);
     fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
     fprintf(ficresprob,"# Age");
     pstamp(ficresprobcov);
     fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
     fprintf(ficresprobcov,"# Age");
     pstamp(ficresprobcor);
     fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
     fprintf(ficresprobcor,"# Age");
   
   
     for(i=1; i<=nlstate;i++)
       for(j=1; j<=(nlstate+ndeath);j++){
         fprintf(ficresprob," p%1d-%1d (SE)",i,j);
         fprintf(ficresprobcov," p%1d-%1d ",i,j);
         fprintf(ficresprobcor," p%1d-%1d ",i,j);
       }  
    /* fprintf(ficresprob,"\n");
     fprintf(ficresprobcov,"\n");
     fprintf(ficresprobcor,"\n");
    */
     xp=vector(1,npar);
     dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
     doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
     mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
     varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
     first=1;
     fprintf(ficgp,"\n# Routine varprob");
     fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
     fprintf(fichtm,"\n");
   
     fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.</li>\n",optionfilehtmcov);
     fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
     fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
   and drawn. It helps understanding how is the covariance between two incidences.\
    They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
     fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
   It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
   would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
   standard deviations wide on each axis. <br>\
    Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
    and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
   To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
   
     cov[1]=1;
     /* tj=cptcoveff; */
     tj = (int) pow(2,cptcoveff);
     if (cptcovn<1) {tj=1;ncodemax[1]=1;}
     j1=0;
     for(j1=1; j1<=tj;j1++){
       /*for(i1=1; i1<=ncodemax[t];i1++){ */
       /*j1++;*/
         if  (cptcovn>0) {
           fprintf(ficresprob, "\n#********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
           fprintf(ficresprob, "**********\n#\n");
           fprintf(ficresprobcov, "\n#********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
           fprintf(ficresprobcov, "**********\n#\n");
           
           fprintf(ficgp, "\n#********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
           fprintf(ficgp, "**********\n#\n");
           
           
           fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
           fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
           
           fprintf(ficresprobcor, "\n#********** Variable ");    
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
           fprintf(ficresprobcor, "**********\n#");    
         }
         
         gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
         trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
         gp=vector(1,(nlstate)*(nlstate+ndeath));
         gm=vector(1,(nlstate)*(nlstate+ndeath));
         for (age=bage; age<=fage; age ++){ 
           cov[2]=age;
           if(nagesqr==1)
             cov[3]= age*age;
           for (k=1; k<=cptcovn;k++) {
             cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
             /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                                                            * 1  1 1 1 1
                                                            * 2  2 1 1 1
                                                            * 3  1 2 1 1
                                                            */
             /* nbcode[1][1]=0 nbcode[1][2]=1;*/
           }
           /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
           for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
           for (k=1; k<=cptcovprod;k++)
             cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
           
       
           for(theta=1; theta <=npar; theta++){
             for(i=1; i<=npar; i++)
               xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
             
             pmij(pmmij,cov,ncovmodel,xp,nlstate);
             
             k=0;
             for(i=1; i<= (nlstate); i++){
               for(j=1; j<=(nlstate+ndeath);j++){
                 k=k+1;
                 gp[k]=pmmij[i][j];
               }
             }
             
             for(i=1; i<=npar; i++)
               xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
       
             pmij(pmmij,cov,ncovmodel,xp,nlstate);
             k=0;
             for(i=1; i<=(nlstate); i++){
               for(j=1; j<=(nlstate+ndeath);j++){
                 k=k+1;
                 gm[k]=pmmij[i][j];
               }
             }
        
             for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
               gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
           }
   
           for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
             for(theta=1; theta <=npar; theta++)
               trgradg[j][theta]=gradg[theta][j];
           
           matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
           matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
   
           pmij(pmmij,cov,ncovmodel,x,nlstate);
           
           k=0;
           for(i=1; i<=(nlstate); i++){
             for(j=1; j<=(nlstate+ndeath);j++){
               k=k+1;
               mu[k][(int) age]=pmmij[i][j];
             }
           }
           for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
             for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
               varpij[i][j][(int)age] = doldm[i][j];
   
           /*printf("\n%d ",(int)age);
             for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
             printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
             fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
             }*/
   
           fprintf(ficresprob,"\n%d ",(int)age);
           fprintf(ficresprobcov,"\n%d ",(int)age);
           fprintf(ficresprobcor,"\n%d ",(int)age);
   
           for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
             fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
           for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
             fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
             fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
           }
           i=0;
           for (k=1; k<=(nlstate);k++){
             for (l=1; l<=(nlstate+ndeath);l++){ 
               i++;
               fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
               fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
               for (j=1; j<=i;j++){
                 /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                 fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                 fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
               }
             }
           }/* end of loop for state */
         } /* end of loop for age */
         free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
         free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
         free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
         free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
         
         /* Confidence intervalle of pij  */
         /*
           fprintf(ficgp,"\nunset parametric;unset label");
           fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
           fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
           fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
           fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
           fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
           fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
         */
   
         /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
         first1=1;first2=2;
         for (k2=1; k2<=(nlstate);k2++){
           for (l2=1; l2<=(nlstate+ndeath);l2++){ 
             if(l2==k2) continue;
             j=(k2-1)*(nlstate+ndeath)+l2;
             for (k1=1; k1<=(nlstate);k1++){
               for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                 if(l1==k1) continue;
                 i=(k1-1)*(nlstate+ndeath)+l1;
                 if(i<=j) continue;
                 for (age=bage; age<=fage; age ++){ 
                   if ((int)age %5==0){
                     v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                     v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                     cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                     mu1=mu[i][(int) age]/stepm*YEARM ;
                     mu2=mu[j][(int) age]/stepm*YEARM;
                     c12=cv12/sqrt(v1*v2);
                     /* Computing eigen value of matrix of covariance */
                     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                     if ((lc2 <0) || (lc1 <0) ){
                       if(first2==1){
                         first1=0;
                       printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                       }
                       fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                       /* lc1=fabs(lc1); */ /* If we want to have them positive */
                       /* lc2=fabs(lc2); */
                     }
   
                     /* Eigen vectors */
                     v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                     /*v21=sqrt(1.-v11*v11); *//* error */
                     v21=(lc1-v1)/cv12*v11;
                     v12=-v21;
                     v22=v11;
                     tnalp=v21/v11;
                     if(first1==1){
                       first1=0;
                       printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                     }
                     fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                     /*printf(fignu*/
                     /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                     /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                     if(first==1){
                       first=0;
                       fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                       fprintf(ficgp,"\nset parametric;unset label");
                       fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                       fprintf(ficgp,"\nset ter svg size 640, 480");
                       fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
    :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">\
   %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
                               subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,\
                               subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                       fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                       fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                       fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                       fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                       fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                       fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",\
                               mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),\
                               mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                     }else{
                       first=0;
                       fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                       fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                       fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                       fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",\
                               mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),\
                               mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                     }/* if first */
                   } /* age mod 5 */
                 } /* end loop age */
                 fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                 first=1;
               } /*l12 */
             } /* k12 */
           } /*l1 */
         }/* k1 */
         /* } */ /* loop covariates */
     }
     free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
     free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
     free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
     free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
     free_vector(xp,1,npar);
     fclose(ficresprob);
     fclose(ficresprobcov);
     fclose(ficresprobcor);
     fflush(ficgp);
     fflush(fichtmcov);
   }
   
   
   /******************* Printing html file ***********/
   void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
                     int lastpass, int stepm, int weightopt, char model[],\
                     int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
                     int popforecast, int estepm ,\
                     double jprev1, double mprev1,double anprev1, \
                     double jprev2, double mprev2,double anprev2){
     int jj1, k1, i1, cpt;
   
      fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
      <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
   </ul>");
      fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n \
    - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> <br>\n ",
              jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
      fprintf(fichtm,"\
    - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
              stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
      fprintf(fichtm,"\
    - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
              subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
      fprintf(fichtm,"\
    - (a) Life expectancies by health status at initial age, ei. (b) health expectancies by health status at initial age, eij . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
      <a href=\"%s\">%s</a> <br>\n",
              estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
      fprintf(fichtm,"\
    - Population projections by age and states: \
      <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
   
   fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
   
    m=pow(2,cptcoveff);
    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
   
    jj1=0;
    for(k1=1; k1<=m;k1++){
      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
        jj1++;
        if (cptcovn > 0) {
          fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
          for (cpt=1; cpt<=cptcoveff;cpt++){ 
            fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);
            printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout);
          }
          fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
        }
        /* aij, bij */
        fprintf(fichtm,"<br>- Logit model, for example: logit(pij)=log(pij/pii)= aij+ bij age + V1 age + etc. as a function of age: <a href=\"%s_%d-1.svg\">%s_%d-1.svg</a><br> \
   <img src=\"%s_%d-1.svg\">",subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1);
        /* Pij */
        fprintf(fichtm,"<br>\n- Pij or Conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2.svg\">%s_%d-2.svg</a><br> \
   <img src=\"%s_%d-2.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1);     
        /* Quasi-incidences */
        fprintf(fichtm,"<br>\n- Iij or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
    before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too,\
    incidence (rates) are the limit when h tends to zero of the ratio of the probability hPij \
   divided by h: hPij/h : <a href=\"%s_%d-3.svg\">%s_%d-3.svg</a><br> \
   <img src=\"%s_%d-3.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1); 
        /* Survival functions (period) in state j */
        for(cpt=1; cpt<=nlstate;cpt++){
          fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> \
   <img src=\"%s_%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,jj1,subdirf2(optionfilefiname,"LIJ_"),cpt,jj1,subdirf2(optionfilefiname,"LIJ_"),cpt,jj1);
        }
        /* State specific survival functions (period) */
        for(cpt=1; cpt<=nlstate;cpt++){
          fprintf(fichtm,"<br>\n- Survival functions from state %d in any different live states and total.\
    Or probability to survive in various states (1 to %d) being in state %d at different ages.\
    <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> <img src=\"%s_%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,jj1,subdirf2(optionfilefiname,"LIJT_"),cpt,jj1,subdirf2(optionfilefiname,"LIJT_"),cpt,jj1);
        }
        /* Period (stable) prevalence in each health state */
        for(cpt=1; cpt<=nlstate;cpt++){
          fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> \
   <img src=\"%s_%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,jj1,subdirf2(optionfilefiname,"P_"),cpt,jj1,subdirf2(optionfilefiname,"P_"),cpt,jj1);
        }
        for(cpt=1; cpt<=nlstate;cpt++) {
          fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s%d%d.svg\">%s%d%d.svg</a> <br> \
   <img src=\"%s_%d%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,jj1,subdirf2(optionfilefiname,"EXP_"),cpt,jj1,subdirf2(optionfilefiname,"EXP_"),cpt,jj1);
        }
      /* } /\* end i1 *\/ */
    }/* End k1 */
    fprintf(fichtm,"</ul>");
   
    fprintf(fichtm,"\
   \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
    - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
    - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file.<br> \
   But because parameters are usually highly correlated (a higher incidence of disability \
   and a higher incidence of recovery can give very close observed transition) it might \
   be very useful to look not only at linear confidence intervals estimated from the \
   variances but at the covariance matrix. And instead of looking at the estimated coefficients \
   (parameters) of the logistic regression, it might be more meaningful to visualize the \
   covariance matrix of the one-step probabilities. \
   See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
   
    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
            subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
    fprintf(fichtm,"\
    - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
            subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
   
    fprintf(fichtm,"\
    - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
            subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
    fprintf(fichtm,"\
    - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
      <a href=\"%s\">%s</a> <br>\n</li>",
              estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
    fprintf(fichtm,"\
    - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
      <a href=\"%s\">%s</a> <br>\n</li>",
              estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
    fprintf(fichtm,"\
    - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
            estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
    fprintf(fichtm,"\
    - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
            estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
    fprintf(fichtm,"\
    - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
            subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
   
   /*  if(popforecast==1) fprintf(fichtm,"\n */
   /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
   /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
   /*      <br>",fileres,fileres,fileres,fileres); */
   /*  else  */
   /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
    fflush(fichtm);
    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
   
    m=pow(2,cptcoveff);
    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
   
    jj1=0;
    for(k1=1; k1<=m;k1++){
      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
        jj1++;
        if (cptcovn > 0) {
          fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
          for (cpt=1; cpt<=cptcoveff;cpt++) 
            fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);
          fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
        }
        for(cpt=1; cpt<=nlstate;cpt++) {
          fprintf(fichtm,"<br>- Observed (cross-sectional) and period (incidence based) \
   prevalence (with 95%% confidence interval) in state (%d): %s%d_%d.svg <br>\
   <img src=\"%s_%d-%d.svg\">",cpt,subdirf2(optionfilefiname,"V_"),cpt,jj1,subdirf2(optionfilefiname,"V_"),cpt,jj1);  
        }
        fprintf(fichtm,"\n<br>- Total life expectancy by age and \
   health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
   true period expectancies (those weighted with period prevalences are also\
    drawn in addition to the population based expectancies computed using\
    observed and cahotic prevalences: %s_%d.svg<br>\
   <img src=\"%s_%d.svg\">",subdirf2(optionfilefiname,"E_"),jj1,subdirf2(optionfilefiname,"E_"),jj1);
      /* } /\* end i1 *\/ */
    }/* End k1 */
    fprintf(fichtm,"</ul>");
    fflush(fichtm);
   }
   
   /******************* Gnuplot file **************/
   void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
   
     char dirfileres[132],optfileres[132];
     int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,ij=0,l=0;
     int ng=0;
     int vpopbased;
   /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
   /*     printf("Problem with file %s",optionfilegnuplot); */
   /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
   /*   } */
   
     /*#ifdef windows */
     fprintf(ficgp,"cd \"%s\" \n",pathc);
       /*#endif */
     m=pow(2,cptcoveff);
   
     strcpy(dirfileres,optionfilefiname);
     strcpy(optfileres,"vpl");
    /* 1eme*/
     fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files\n");
     for (cpt=1; cpt<= nlstate ; cpt ++) {
       for (k1=1; k1<= m ; k1 ++) { /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
        fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1);
        fprintf(ficgp,"\n#set out \"V_%s_%d-%d.svg\" \n",optionfilefiname,cpt,k1);
        fprintf(ficgp,"set xlabel \"Age\" \n\
   set ylabel \"Probability\" \n\
   set ter svg size 640, 480\n\
   plot [%.f:%.f] \"%s\" every :::%d::%d u 1:2 \"%%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1);
   
        for (i=1; i<= nlstate ; i ++) {
          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
          else        fprintf(ficgp," %%*lf (%%*lf)");
        }
        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2+1.96*$3) \"%%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1);
        for (i=1; i<= nlstate ; i ++) {
          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
          else fprintf(ficgp," %%*lf (%%*lf)");
        } 
        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2-1.96*$3) \"%%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1); 
        for (i=1; i<= nlstate ; i ++) {
          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
          else fprintf(ficgp," %%*lf (%%*lf)");
        }  
        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence \" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1));
        fprintf(ficgp,"\nset out \n");
       } /* k1 */
     } /* cpt */
     /*2 eme*/
     fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files\n");
     for (k1=1; k1<= m ; k1 ++) { 
       fprintf(ficgp,"\nset out \"%s_%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1);
       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
         if(vpopbased==0)
           fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
         else
           fprintf(ficgp,"\nreplot ");
         for (i=1; i<= nlstate+1 ; i ++) {
           k=2*i;
           fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1, vpopbased);
           for (j=1; j<= nlstate+1 ; j ++) {
             if (j==i) fprintf(ficgp," %%lf (%%lf)");
             else fprintf(ficgp," %%*lf (%%*lf)");
           }   
           if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
           else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
           fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
           for (j=1; j<= nlstate+1 ; j ++) {
             if (j==i) fprintf(ficgp," %%lf (%%lf)");
             else fprintf(ficgp," %%*lf (%%*lf)");
           }   
           fprintf(ficgp,"\" t\"\" w l lt 0,");
           fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
           for (j=1; j<= nlstate+1 ; j ++) {
             if (j==i) fprintf(ficgp," %%lf (%%lf)");
             else fprintf(ficgp," %%*lf (%%*lf)");
           }   
           if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
           else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
         } /* state */
       } /* vpopbased */
       fprintf(ficgp,"\nset out;set out \"%s_%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1); /* Buggy gnuplot */
     } /* k1 */
     /*3eme*/
     
     for (k1=1; k1<= m ; k1 ++) { 
       for (cpt=1; cpt<= nlstate ; cpt ++) {
         /*       k=2+nlstate*(2*cpt-2); */
         k=2+(nlstate+1)*(cpt-1);
         fprintf(ficgp,"\nset out \"%s_%d%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1);
         fprintf(ficgp,"set ter svg size 640, 480\n\
   plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),k1-1,k1-1,k,cpt);
         /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
           for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
           fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
           fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
           for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
           fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
           
         */
         for (i=1; i< nlstate ; i ++) {
           fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+i,cpt,i+1);
           /*      fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
           
         } 
         fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+nlstate,cpt);
       }
     }
     
     /* Survival functions (period) from state i in state j by initial state i */
     for (k1=1; k1<= m ; k1 ++) { /* For each multivariate if any */
       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
         k=3;
         fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'lij' files, cov=%d state=%d",k1, cpt);
         fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1);
         fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
   set ter svg size 640, 480\n\
   unset log y\n\
   plot [%.f:%.f]  ", ageminpar, agemaxpar);
         for (i=1; i<= nlstate ; i ++){
           if(i==1)
             fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
           else
             fprintf(ficgp,", '' ");
           l=(nlstate+ndeath)*(i-1)+1;
           fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
           for (j=2; j<= nlstate+ndeath ; j ++)
             fprintf(ficgp,"+$%d",k+l+j-1);
           fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
         } /* nlstate */
         fprintf(ficgp,"\nset out\n");
       } /* end cpt state*/ 
     } /* end covariate */  
   
     /* Survival functions (period) from state i in state j by final state j */
     for (k1=1; k1<= m ; k1 ++) { /* For each multivariate if any */
       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
         k=3;
         fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
         fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1);
         fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
   set ter svg size 640, 480\n\
   unset log y\n\
   plot [%.f:%.f]  ", ageminpar, agemaxpar);
         for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
           if(j==1)
             fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
           else
             fprintf(ficgp,", '' ");
           l=(nlstate+ndeath)*(cpt-1) +j;
           fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
           /* for (i=2; i<= nlstate+ndeath ; i ++) */
           /*   fprintf(ficgp,"+$%d",k+l+i-1); */
           fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
         } /* nlstate */
         fprintf(ficgp,", '' ");
         fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
         for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
           l=(nlstate+ndeath)*(cpt-1) +j;
           if(j < nlstate)
             fprintf(ficgp,"$%d +",k+l);
           else
             fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
         }
         fprintf(ficgp,"\nset out\n");
       } /* end cpt state*/ 
     } /* end covariate */  
   
     /* CV preval stable (period) */
     for (k1=1; k1<= m ; k1 ++) { /* For each multivariate if any */
       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
         k=3;
         fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, cov=%d state=%d",k1, cpt);
         fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1);
         fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
   set ter svg size 640, 480\n\
   unset log y\n\
   plot [%.f:%.f]  ", ageminpar, agemaxpar);
         for (i=1; i<= nlstate ; i ++){
           if(i==1)
             fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
           else
             fprintf(ficgp,", '' ");
           l=(nlstate+ndeath)*(i-1)+1;
           fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
           for (j=2; j<= nlstate ; j ++)
             fprintf(ficgp,"+$%d",k+l+j-1);
           fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
         } /* nlstate */
         fprintf(ficgp,"\nset out\n");
       } /* end cpt state*/ 
     } /* end covariate */  
   
     /* proba elementaires */
     fprintf(ficgp,"\n##############\n#MLE estimated parameters\n#############\n");
     for(i=1,jk=1; i <=nlstate; i++){
       fprintf(ficgp,"# initial state %d\n",i);
       for(k=1; k <=(nlstate+ndeath); k++){
         if (k != i) {
           fprintf(ficgp,"#   current state %d\n",k);
           for(j=1; j <=ncovmodel; j++){
             fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
             jk++; 
           }
           fprintf(ficgp,"\n");
         }
       }
      }
     fprintf(ficgp,"##############\n#\n");
   
     /*goto avoid;*/
     fprintf(ficgp,"\n##############\n#Graphics of probabilities or incidences\n#############\n");
     fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
     fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
     fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
     fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
     fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
     fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
     fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
     fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
     fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
     fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
     fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
     fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
     fprintf(ficgp,"#\n");
      for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
        fprintf(ficgp,"# ng=%d\n",ng);
        fprintf(ficgp,"#   jk=1 to 2^%d=%d\n",cptcoveff,m);
        for(jk=1; jk <=m; jk++) {
          fprintf(ficgp,"#    jk=%d\n",jk);
          fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng);
          fprintf(ficgp,"\nset ter svg size 640, 480 ");
          if (ng==1){
            fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
            fprintf(ficgp,"\nunset log y");
          }else if (ng==2){
            fprintf(ficgp,"\nset ylabel \"Probability\"\n");
            fprintf(ficgp,"\nset log y");
          }else if (ng==3){
            fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
            fprintf(ficgp,"\nset log y");
          }else
            fprintf(ficgp,"\nunset title ");
          fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
          i=1;
          for(k2=1; k2<=nlstate; k2++) {
            k3=i;
            for(k=1; k<=(nlstate+ndeath); k++) {
              if (k != k2){
                switch( ng) {
                case 1:
                  if(nagesqr==0)
                    fprintf(ficgp," p%d+p%d*x",i,i+1);
                  else /* nagesqr =1 */
                    fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                  break;
                case 2: /* ng=2 */
                  if(nagesqr==0)
                    fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                  else /* nagesqr =1 */
                      fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                  break;
                case 3:
                  if(nagesqr==0)
                    fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                  else /* nagesqr =1 */
                    fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                  break;
                }
                ij=1;/* To be checked else nbcode[0][0] wrong */
                for(j=3; j <=ncovmodel-nagesqr; j++) {
                  /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
                  if(ij <=cptcovage) { /* Bug valgrind */
                    if((j-2)==Tage[ij]) { /* Bug valgrind */
                      fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                      ij++;
                    }
                  }
                  else
                    fprintf(ficgp,"+p%d*%d",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                }
                if(ng != 1){
                  fprintf(ficgp,")/(1");
                
                  for(k1=1; k1 <=nlstate; k1++){ 
                    if(nagesqr==0)
                      fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                    else /* nagesqr =1 */
                      fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1,k3+(k1-1)*ncovmodel+1+nagesqr);
                    
                    ij=1;
                    for(j=3; j <=ncovmodel-nagesqr; j++){
                      if(ij <=cptcovage) { /* Bug valgrind */
                        if((j-2)==Tage[ij]) { /* Bug valgrind */
                          fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                          /* fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                          ij++;
                        }
                      }
                      else
                        fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                    }
                    fprintf(ficgp,")");
                  }
                  fprintf(ficgp,")");
                  if(ng ==2)
                    fprintf(ficgp," t \"p%d%d\" ", k2,k);
                  else /* ng= 3 */
                    fprintf(ficgp," t \"i%d%d\" ", k2,k);
                }else{ /* end ng <> 1 */
                  fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                }
                if ((k+k2)!= (nlstate*2+ndeath)) fprintf(ficgp,",");
                i=i+ncovmodel;
              }
            } /* end k */
          } /* end k2 */
          fprintf(ficgp,"\n set out\n");
        } /* end jk */
      } /* end ng */
    /* avoid: */
      fflush(ficgp); 
   }  /* end gnuplot */
   
   
   /*************** Moving average **************/
   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav){
   
     int i, cpt, cptcod;
     int modcovmax =1;
     int mobilavrange, mob;
     double age;
   
     modcovmax=2*cptcoveff;/* Max number of modalities. We suppose 
                              a covariate has 2 modalities */
     if (cptcovn<1) modcovmax=1; /* At least 1 pass */
   
     if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
       if(mobilav==1) mobilavrange=5; /* default */
       else mobilavrange=mobilav;
       for (age=bage; age<=fage; age++)
         for (i=1; i<=nlstate;i++)
           for (cptcod=1;cptcod<=modcovmax;cptcod++)
             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
       /* We keep the original values on the extreme ages bage, fage and for 
          fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
          we use a 5 terms etc. until the borders are no more concerned. 
       */ 
       for (mob=3;mob <=mobilavrange;mob=mob+2){
         for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
           for (i=1; i<=nlstate;i++){
             for (cptcod=1;cptcod<=modcovmax;cptcod++){
               mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                 for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                 }
               mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
             }
           }
         }/* end age */
       }/* end mob */
     }else return -1;
     return 0;
   }/* End movingaverage */
   
   
   /************** Forecasting ******************/
   void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
     /* proj1, year, month, day of starting projection 
        agemin, agemax range of age
        dateprev1 dateprev2 range of dates during which prevalence is computed
        anproj2 year of en of projection (same day and month as proj1).
     */
     int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1;
     double agec; /* generic age */
     double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
     double *popeffectif,*popcount;
     double ***p3mat;
     double ***mobaverage;
     char fileresf[FILENAMELENGTH];
   
     agelim=AGESUP;
     prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
    
     strcpy(fileresf,"F_"); 
     strcat(fileresf,fileresu);
     if((ficresf=fopen(fileresf,"w"))==NULL) {
       printf("Problem with forecast resultfile: %s\n", fileresf);
       fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
     }
     printf("Computing forecasting: result on file '%s' \n", fileresf);
     fprintf(ficlog,"Computing forecasting: result on file '%s' \n", fileresf);
   
     if (cptcoveff==0) ncodemax[cptcoveff]=1;
   
     if (mobilav!=0) {
       mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){
         fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
         printf(" Error in movingaverage mobilav=%d\n",mobilav);
       }
     }
   
     stepsize=(int) (stepm+YEARM-1)/YEARM;
     if (stepm<=12) stepsize=1;
     if(estepm < stepm){
       printf ("Problem %d lower than %d\n",estepm, stepm);
     }
     else  hstepm=estepm;   
   
     hstepm=hstepm/stepm; 
     yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                                  fractional in yp1 */
     anprojmean=yp;
     yp2=modf((yp1*12),&yp);
     mprojmean=yp;
     yp1=modf((yp2*30.5),&yp);
     jprojmean=yp;
     if(jprojmean==0) jprojmean=1;
     if(mprojmean==0) jprojmean=1;
   
     i1=cptcoveff;
     if (cptcovn < 1){i1=1;}
     
     fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
     
     fprintf(ficresf,"#****** Routine prevforecast **\n");
   
   /*            if (h==(int)(YEARM*yearp)){ */
     for(cptcov=1, k=0;cptcov<=i1;cptcov++){
       for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){
         k=k+1;
         fprintf(ficresf,"\n#******");
         for(j=1;j<=cptcoveff;j++) {
           fprintf(ficresf," V%d=%d, hpijx=probability over h years, hp.jx is weighted by observed prev ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
         }
         fprintf(ficresf,"******\n");
         fprintf(ficresf,"# Covariate valuofcovar yearproj age");
         for(j=1; j<=nlstate+ndeath;j++){ 
           for(i=1; i<=nlstate;i++)              
             fprintf(ficresf," p%d%d",i,j);
           fprintf(ficresf," p.%d",j);
         }
         for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) { 
           fprintf(ficresf,"\n");
           fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
   
           for (agec=fage; agec>=(ageminpar-1); agec--){ 
             nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
             nhstepm = nhstepm/hstepm; 
             p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             oldm=oldms;savm=savms;
             hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k);  
           
             for (h=0; h<=nhstepm; h++){
               if (h*hstepm/YEARM*stepm ==yearp) {
                 fprintf(ficresf,"\n");
                 for(j=1;j<=cptcoveff;j++) 
                   fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                 fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
               } 
               for(j=1; j<=nlstate+ndeath;j++) {
                 ppij=0.;
                 for(i=1; i<=nlstate;i++) {
                   if (mobilav==1) 
                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod];
                   else {
                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod];
                   }
                   if (h*hstepm/YEARM*stepm== yearp) {
                     fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   }
                 } /* end i */
                 if (h*hstepm/YEARM*stepm==yearp) {
                   fprintf(ficresf," %.3f", ppij);
                 }
               }/* end j */
             } /* end h */
             free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           } /* end agec */
         } /* end yearp */
       } /* end cptcod */
     } /* end  cptcov */
          
     if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
   
     fclose(ficresf);
   }
   
   /************** Forecasting *****not tested NB*************/
   void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){
     
     int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h;
     int *popage;
     double calagedatem, agelim, kk1, kk2;
     double *popeffectif,*popcount;
     double ***p3mat,***tabpop,***tabpopprev;
     double ***mobaverage;
     char filerespop[FILENAMELENGTH];
   
     tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     agelim=AGESUP;
     calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM;
     
     prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
     
     
     strcpy(filerespop,"POP_"); 
     strcat(filerespop,fileresu);
     if((ficrespop=fopen(filerespop,"w"))==NULL) {
       printf("Problem with forecast resultfile: %s\n", filerespop);
       fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop);
     }
     printf("Computing forecasting: result on file '%s' \n", filerespop);
     fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop);
   
     if (cptcoveff==0) ncodemax[cptcoveff]=1;
   
     if (mobilav!=0) {
       mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){
         fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
         printf(" Error in movingaverage mobilav=%d\n",mobilav);
       }
     }
   
     stepsize=(int) (stepm+YEARM-1)/YEARM;
     if (stepm<=12) stepsize=1;
     
     agelim=AGESUP;
     
     hstepm=1;
     hstepm=hstepm/stepm; 
     
     if (popforecast==1) {
       if((ficpop=fopen(popfile,"r"))==NULL) {
         printf("Problem with population file : %s\n",popfile);exit(0);
         fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0);
       } 
       popage=ivector(0,AGESUP);
       popeffectif=vector(0,AGESUP);
       popcount=vector(0,AGESUP);
       
       i=1;   
       while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1;
      
       imx=i;
       for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i];
     }
   
     for(cptcov=1,k=0;cptcov<=i2;cptcov++){
      for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){
         k=k+1;
         fprintf(ficrespop,"\n#******");
         for(j=1;j<=cptcoveff;j++) {
           fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
         }
         fprintf(ficrespop,"******\n");
         fprintf(ficrespop,"# Age");
         for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j);
         if (popforecast==1)  fprintf(ficrespop," [Population]");
         
         for (cpt=0; cpt<=0;cpt++) { 
           fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);   
           
           for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){ 
             nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); 
             nhstepm = nhstepm/hstepm; 
             
             p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             oldm=oldms;savm=savms;
             hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
           
             for (h=0; h<=nhstepm; h++){
               if (h==(int) (calagedatem+YEARM*cpt)) {
                 fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm);
               } 
               for(j=1; j<=nlstate+ndeath;j++) {
                 kk1=0.;kk2=0;
                 for(i=1; i<=nlstate;i++) {              
                   if (mobilav==1) 
                     kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod];
                   else {
                     kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod];
                   }
                 }
                 if (h==(int)(calagedatem+12*cpt)){
                   tabpop[(int)(agedeb)][j][cptcod]=kk1;
                     /*fprintf(ficrespop," %.3f", kk1);
                       if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*/
                 }
               }
               for(i=1; i<=nlstate;i++){
                 kk1=0.;
                   for(j=1; j<=nlstate;j++){
                     kk1= kk1+tabpop[(int)(agedeb)][j][cptcod]; 
                   }
                     tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)];
               }
   
               if (h==(int)(calagedatem+12*cpt)) for(j=1; j<=nlstate;j++) 
                 fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]);
             }
             free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           }
         }
    
     /******/
   
         for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) { 
           fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);   
           for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){ 
             nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); 
             nhstepm = nhstepm/hstepm; 
             
             p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             oldm=oldms;savm=savms;
             hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
             for (h=0; h<=nhstepm; h++){
               if (h==(int) (calagedatem+YEARM*cpt)) {
                 fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm);
               } 
               for(j=1; j<=nlstate+ndeath;j++) {
                 kk1=0.;kk2=0;
                 for(i=1; i<=nlstate;i++) {              
                   kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];    
                 }
                 if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);        
               }
             }
             free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           }
         }
      } 
     }
    
     if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
   
     if (popforecast==1) {
       free_ivector(popage,0,AGESUP);
       free_vector(popeffectif,0,AGESUP);
       free_vector(popcount,0,AGESUP);
     }
     free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     fclose(ficrespop);
   } /* End of popforecast */
   
   int fileappend(FILE *fichier, char *optionfich)
   {
     if((fichier=fopen(optionfich,"a"))==NULL) {
       printf("Problem with file: %s\n", optionfich);
       fprintf(ficlog,"Problem with file: %s\n", optionfich);
       return (0);
     }
     fflush(fichier);
     return (1);
   }
   
   
   /**************** function prwizard **********************/
   void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
   {
   
     /* Wizard to print covariance matrix template */
   
     char ca[32], cb[32];
     int i,j, k, li, lj, lk, ll, jj, npar, itimes;
     int numlinepar;
   
     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
     fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
     for(i=1; i <=nlstate; i++){
       jj=0;
       for(j=1; j <=nlstate+ndeath; j++){
         if(j==i) continue;
         jj++;
         /*ca[0]= k+'a'-1;ca[1]='\0';*/
         printf("%1d%1d",i,j);
         fprintf(ficparo,"%1d%1d",i,j);
         for(k=1; k<=ncovmodel;k++){
           /*        printf(" %lf",param[i][j][k]); */
           /*        fprintf(ficparo," %lf",param[i][j][k]); */
           printf(" 0.");
           fprintf(ficparo," 0.");
         }
         printf("\n");
         fprintf(ficparo,"\n");
       }
     }
     printf("# Scales (for hessian or gradient estimation)\n");
     fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
     npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
     for(i=1; i <=nlstate; i++){
       jj=0;
       for(j=1; j <=nlstate+ndeath; j++){
         if(j==i) continue;
         jj++;
         fprintf(ficparo,"%1d%1d",i,j);
         printf("%1d%1d",i,j);
         fflush(stdout);
         for(k=1; k<=ncovmodel;k++){
           /*      printf(" %le",delti3[i][j][k]); */
           /*      fprintf(ficparo," %le",delti3[i][j][k]); */
           printf(" 0.");
           fprintf(ficparo," 0.");
         }
         numlinepar++;
         printf("\n");
         fprintf(ficparo,"\n");
       }
     }
     printf("# Covariance matrix\n");
   /* # 121 Var(a12)\n\ */
   /* # 122 Cov(b12,a12) Var(b12)\n\ */
   /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
   /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
   /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
   /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
   /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
   /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
     fflush(stdout);
     fprintf(ficparo,"# Covariance matrix\n");
     /* # 121 Var(a12)\n\ */
     /* # 122 Cov(b12,a12) Var(b12)\n\ */
     /* #   ...\n\ */
     /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
     
     for(itimes=1;itimes<=2;itimes++){
       jj=0;
       for(i=1; i <=nlstate; i++){
         for(j=1; j <=nlstate+ndeath; j++){
           if(j==i) continue;
           for(k=1; k<=ncovmodel;k++){
             jj++;
             ca[0]= k+'a'-1;ca[1]='\0';
             if(itimes==1){
               printf("#%1d%1d%d",i,j,k);
               fprintf(ficparo,"#%1d%1d%d",i,j,k);
             }else{
               printf("%1d%1d%d",i,j,k);
               fprintf(ficparo,"%1d%1d%d",i,j,k);
               /*  printf(" %.5le",matcov[i][j]); */
             }
             ll=0;
             for(li=1;li <=nlstate; li++){
               for(lj=1;lj <=nlstate+ndeath; lj++){
                 if(lj==li) continue;
                 for(lk=1;lk<=ncovmodel;lk++){
                   ll++;
                   if(ll<=jj){
                     cb[0]= lk +'a'-1;cb[1]='\0';
                     if(ll<jj){
                       if(itimes==1){
                         printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                         fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                       }else{
                         printf(" 0.");
                         fprintf(ficparo," 0.");
                       }
                     }else{
                       if(itimes==1){
                         printf(" Var(%s%1d%1d)",ca,i,j);
                         fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                       }else{
                         printf(" 0.");
                         fprintf(ficparo," 0.");
                       }
                     }
                   }
                 } /* end lk */
               } /* end lj */
             } /* end li */
             printf("\n");
             fprintf(ficparo,"\n");
             numlinepar++;
           } /* end k*/
         } /*end j */
       } /* end i */
     } /* end itimes */
   
   } /* end of prwizard */
   /******************* Gompertz Likelihood ******************************/
   double gompertz(double x[])
   { 
     double A,B,L=0.0,sump=0.,num=0.;
     int i,n=0; /* n is the size of the sample */
   
     for (i=0;i<=imx-1 ; i++) {
       sump=sump+weight[i];
       /*    sump=sump+1;*/
       num=num+1;
     }
    
    
     /* for (i=0; i<=imx; i++) 
        if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
   
     for (i=1;i<=imx ; i++)
       {
         if (cens[i] == 1 && wav[i]>1)
           A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
         
         if (cens[i] == 0 && wav[i]>1)
           A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
         
         /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
         if (wav[i] > 1 ) { /* ??? */
           L=L+A*weight[i];
           /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
         }
       }
   
    /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
    
     return -2*L*num/sump;
   }
   
   #ifdef GSL
   /******************* Gompertz_f Likelihood ******************************/
   double gompertz_f(const gsl_vector *v, void *params)
   { 
     double A,B,LL=0.0,sump=0.,num=0.;
     double *x= (double *) v->data;
     int i,n=0; /* n is the size of the sample */
   
     for (i=0;i<=imx-1 ; i++) {
       sump=sump+weight[i];
       /*    sump=sump+1;*/
       num=num+1;
     }
    
    
     /* for (i=0; i<=imx; i++) 
        if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
     printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
     for (i=1;i<=imx ; i++)
       {
         if (cens[i] == 1 && wav[i]>1)
           A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
         
         if (cens[i] == 0 && wav[i]>1)
           A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
         
         /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
         if (wav[i] > 1 ) { /* ??? */
           LL=LL+A*weight[i];
           /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
         }
       }
   
    /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
     printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
    
     return -2*LL*num/sump;
   }
   #endif
   
   /******************* Printing html file ***********/
   void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
                     int lastpass, int stepm, int weightopt, char model[],\
                     int imx,  double p[],double **matcov,double agemortsup){
     int i,k;
   
     fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
     fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
     for (i=1;i<=2;i++) 
       fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
     fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
     fprintf(fichtm,"</ul>");
   
   fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
   
    fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
   
    for (k=agegomp;k<(agemortsup-2);k++) 
      fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
   
    
     fflush(fichtm);
   }
   
   /******************* Gnuplot file **************/
   void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
   
     char dirfileres[132],optfileres[132];
   
     int ng;
   
   
     /*#ifdef windows */
     fprintf(ficgp,"cd \"%s\" \n",pathc);
       /*#endif */
   
   
     strcpy(dirfileres,optionfilefiname);
     strcpy(optfileres,"vpl");
     fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
     fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
     fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
     /* fprintf(ficgp, "set size 0.65,0.65\n"); */
     fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
   
   } 
   
   int readdata(char datafile[], int firstobs, int lastobs, int *imax)
   {
   
     /*-------- data file ----------*/
     FILE *fic;
     char dummy[]="                         ";
     int i=0, j=0, n=0;
     int linei, month, year,iout;
     char line[MAXLINE], linetmp[MAXLINE];
     char stra[MAXLINE], strb[MAXLINE];
     char *stratrunc;
     int lstra;
   
   
     if((fic=fopen(datafile,"r"))==NULL)    {
       printf("Problem while opening datafile: %s\n", datafile);fflush(stdout);
       fprintf(ficlog,"Problem while opening datafile: %s\n", datafile);fflush(ficlog);return 1;
     }
   
     i=1;
     linei=0;
     while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
       linei=linei+1;
       for(j=strlen(line); j>=0;j--){  /* Untabifies line */
         if(line[j] == '\t')
           line[j] = ' ';
       }
       for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
         ;
       };
       line[j+1]=0;  /* Trims blanks at end of line */
       if(line[0]=='#'){
         fprintf(ficlog,"Comment line\n%s\n",line);
         printf("Comment line\n%s\n",line);
         continue;
       }
       trimbb(linetmp,line); /* Trims multiple blanks in line */
       strcpy(line, linetmp);
     
   
       for (j=maxwav;j>=1;j--){
         cutv(stra, strb, line, ' '); 
         if(strb[0]=='.') { /* Missing status */
           lval=-1;
         }else{
           errno=0;
           lval=strtol(strb,&endptr,10); 
         /*        if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
           if( strb[0]=='\0' || (*endptr != '\0')){
             printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
             fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
             return 1;
           }
         }
         s[j][i]=lval;
         
         strcpy(line,stra);
         cutv(stra, strb,line,' ');
         if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
         }
         else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
           month=99;
           year=9999;
         }else{
           printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
           fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
           return 1;
         }
         anint[j][i]= (double) year; 
         mint[j][i]= (double)month; 
         strcpy(line,stra);
       } /* ENd Waves */
       
       cutv(stra, strb,line,' '); 
       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
       }
       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
         month=99;
         year=9999;
       }else{
         printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
           fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
           return 1;
       }
       andc[i]=(double) year; 
       moisdc[i]=(double) month; 
       strcpy(line,stra);
       
       cutv(stra, strb,line,' '); 
       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
       }
       else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
         month=99;
         year=9999;
       }else{
         printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
         fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
           return 1;
       }
       if (year==9999) {
         printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
         fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
           return 1;
   
       }
       annais[i]=(double)(year);
       moisnais[i]=(double)(month); 
       strcpy(line,stra);
       
       cutv(stra, strb,line,' '); 
       errno=0;
       dval=strtod(strb,&endptr); 
       if( strb[0]=='\0' || (*endptr != '\0')){
         printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
         fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
         fflush(ficlog);
         return 1;
       }
       weight[i]=dval; 
       strcpy(line,stra);
       
       for (j=ncovcol;j>=1;j--){
         cutv(stra, strb,line,' '); 
         if(strb[0]=='.') { /* Missing status */
           lval=-1;
         }else{
           errno=0;
           lval=strtol(strb,&endptr,10); 
           if( strb[0]=='\0' || (*endptr != '\0')){
             printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
             fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
             return 1;
           }
         }
         if(lval <-1 || lval >1){
           printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
    Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
    for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
    For example, for multinomial values like 1, 2 and 3,\n \
    build V1=0 V2=0 for the reference value (1),\n \
           V1=1 V2=0 for (2) \n \
    and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
    output of IMaCh is often meaningless.\n \
    Exiting.\n",lval,linei, i,line,j);
           fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
    Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
    for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
    For example, for multinomial values like 1, 2 and 3,\n \
    build V1=0 V2=0 for the reference value (1),\n \
           V1=1 V2=0 for (2) \n \
    and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
    output of IMaCh is often meaningless.\n \
    Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
           return 1;
         }
         covar[j][i]=(double)(lval);
         strcpy(line,stra);
       }  
       lstra=strlen(stra);
        
       if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
         stratrunc = &(stra[lstra-9]);
         num[i]=atol(stratrunc);
       }
       else
         num[i]=atol(stra);
       /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
         printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
       
       i=i+1;
     } /* End loop reading  data */
   
     *imax=i-1; /* Number of individuals */
     fclose(fic);
    
     return (0);
     /* endread: */
       printf("Exiting readdata: ");
       fclose(fic);
       return (1);
   
   
   
   }
   void removespace(char *str) {
     char *p1 = str, *p2 = str;
     do
       while (*p2 == ' ')
         p2++;
     while (*p1++ == *p2++);
   }
   
   int decodemodel ( char model[], int lastobs) /**< This routine decode the model and returns:
      * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
      * - nagesqr = 1 if age*age in the model, otherwise 0.
      * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
      * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
      * - cptcovage number of covariates with age*products =2
      * - cptcovs number of simple covariates
      * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
      *     which is a new column after the 9 (ncovcol) variables. 
      * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
      * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
      *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
      * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
    */
   {
     int i, j, k, ks;
     int  j1, k1, k2;
     char modelsav[80];
     char stra[80], strb[80], strc[80], strd[80],stre[80];
     char *strpt;
   
     /*removespace(model);*/
     if (strlen(model) >1){ /* If there is at least 1 covariate */
       j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
       if (strstr(model,"AGE") !=0){
         printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
         fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
         return 1;
       }
       if (strstr(model,"v") !=0){
         printf("Error. 'v' must be in upper case 'V' model=%s ",model);
         fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
         return 1;
       }
       strcpy(modelsav,model); 
       if ((strpt=strstr(model,"age*age")) !=0){
         printf(" strpt=%s, model=%s\n",strpt, model);
         if(strpt != model){
         printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
    'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
    corresponding column of parameters.\n",model);
         fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
    'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
    corresponding column of parameters.\n",model); fflush(ficlog);
         return 1;
       }
   
         nagesqr=1;
         if (strstr(model,"+age*age") !=0)
           substrchaine(modelsav, model, "+age*age");
         else if (strstr(model,"age*age+") !=0)
           substrchaine(modelsav, model, "age*age+");
         else 
           substrchaine(modelsav, model, "age*age");
       }else
         nagesqr=0;
       if (strlen(modelsav) >1){
         j=nbocc(modelsav,'+'); /**< j=Number of '+' */
         j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
         cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =2  */
         cptcovt= j+1; /* Number of total covariates in the model, not including
                      * cst, age and age*age 
                      * V1+V1*age+ V3 + V3*V4+age*age=> 4*/
                     /* including age products which are counted in cptcovage.
                     * but the covariates which are products must be treated 
                     * separately: ncovn=4- 2=2 (V1+V3). */
         cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
         cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
   
       
         /*   Design
          *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
          *  <          ncovcol=8                >
          * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
          *   k=  1    2      3       4     5       6      7        8
          *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
          *  covar[k,i], value of kth covariate if not including age for individual i:
          *       covar[1][i]= (V2), covar[4][i]=(V3), covar[8][i]=(V8)
          *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[4]=3 Tvar[8]=8
          *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
          *  Tage[++cptcovage]=k
          *       if products, new covar are created after ncovcol with k1
          *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
          *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
          *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
          *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
          *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
          *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
          *  <          ncovcol=8                >
          *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
          *          k=  1    2      3       4     5       6      7        8    9   10   11  12
          *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
          * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
          * p Tprod[1]@2={                         6, 5}
          *p Tvard[1][1]@4= {7, 8, 5, 6}
          * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
          *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
          *How to reorganize?
          * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
          * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
          *       {2,   1,     4,      8,    5,      6,     3,       7}
          * Struct []
          */
   
         /* This loop fills the array Tvar from the string 'model'.*/
         /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
         /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
         /*        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
         /*        k=3 V4 Tvar[k=3]= 4 (from V4) */
         /*        k=2 V1 Tvar[k=2]= 1 (from V1) */
         /*        k=1 Tvar[1]=2 (from V2) */
         /*        k=5 Tvar[5] */
         /* for (k=1; k<=cptcovn;k++) { */
         /*        cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
         /*        } */
         /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
         /*
          * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
         for(k=cptcovt; k>=1;k--) /**< Number of covariates */
           Tvar[k]=0;
         cptcovage=0;
         for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
           cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
                                            modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
           if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
           /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
           /*scanf("%d",i);*/
           if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
             cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
             if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
               /* covar is not filled and then is empty */
               cptcovprod--;
               cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
               Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
               cptcovage++; /* Sums the number of covariates which include age as a product */
               Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
               /*printf("stre=%s ", stre);*/
             } else if (strcmp(strd,"age")==0) { /* or age*Vn */
               cptcovprod--;
               cutl(stre,strb,strc,'V');
               Tvar[k]=atoi(stre);
               cptcovage++;
               Tage[cptcovage]=k;
             } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
               /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
               cptcovn++;
               cptcovprodnoage++;k1++;
               cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
               Tvar[k]=ncovcol+k1; /* For model-covariate k tells which data-covariate to use but
                                      because this model-covariate is a construction we invent a new column
                                      ncovcol + k1
                                      If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                                      Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
               cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
               Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
               Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
               Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
               k2=k2+2;
               Tvar[cptcovt+k2]=Tvard[k1][1]; /* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) */
               Tvar[cptcovt+k2+1]=Tvard[k1][2];  /* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) */
               for (i=1; i<=lastobs;i++){
                 /* Computes the new covariate which is a product of
                    covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                 covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
               }
             } /* End age is not in the model */
           } /* End if model includes a product */
           else { /* no more sum */
             /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
             /*  scanf("%d",i);*/
             cutl(strd,strc,strb,'V');
             ks++; /**< Number of simple covariates */
             cptcovn++;
             Tvar[k]=atoi(strd);
           }
           strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
           /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
             scanf("%d",i);*/
         } /* end of loop + on total covariates */
       } /* end if strlen(modelsave == 0) age*age might exist */
     } /* end if strlen(model == 0) */
     
     /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
       If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
   
     /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
     printf("cptcovprod=%d ", cptcovprod);
     fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
   
     scanf("%d ",i);*/
   
   
     return (0); /* with covar[new additional covariate if product] and Tage if age */ 
     /*endread:*/
       printf("Exiting decodemodel: ");
       return (1);
   }
   
   int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
   {
     int i, m;
   
     for (i=1; i<=imx; i++) {
       for(m=2; (m<= maxwav); m++) {
         if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
           anint[m][i]=9999;
           s[m][i]=-1;
         }
         if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
           *nberr = *nberr + 1;
           printf("Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results are biased (%d)\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr);
           fprintf(ficlog,"Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results are biased (%d)\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr);
           s[m][i]=-1;
         }
         if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
           (*nberr)++;
           printf("Error! Month of death of individual %ld on line %d was unknown %2d, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,(int)moisdc[i]); 
           fprintf(ficlog,"Error! Month of death of individual %ld on line %d was unknown %f, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,moisdc[i]); 
           s[m][i]=-1; /* We prefer to skip it (and to skip it in version 0.8a1 too */
         }
       }
     }
   
     for (i=1; i<=imx; i++)  {
       agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
       for(m=firstpass; (m<= lastpass); m++){
         if(s[m][i] >0 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){
           if (s[m][i] >= nlstate+1) {
             if(agedc[i]>0){
               if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
                 agev[m][i]=agedc[i];
             /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
               }else {
                 if ((int)andc[i]!=9999){
                   nbwarn++;
                   printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   agev[m][i]=-1;
                 }
               }
             } /* agedc > 0 */
           }
           else if(s[m][i] !=9){ /* Standard case, age in fractional
                                    years but with the precision of a month */
             agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
             if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
               agev[m][i]=1;
             else if(agev[m][i] < *agemin){ 
               *agemin=agev[m][i];
               printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
             }
             else if(agev[m][i] >*agemax){
               *agemax=agev[m][i];
               /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
             }
             /*agev[m][i]=anint[m][i]-annais[i];*/
             /*     agev[m][i] = age[i]+2*m;*/
           }
           else { /* =9 */
             agev[m][i]=1;
             s[m][i]=-1;
           }
         }
         else /*= 0 Unknown */
           agev[m][i]=1;
       }
       
     }
     for (i=1; i<=imx; i++)  {
       for(m=firstpass; (m<=lastpass); m++){
         if (s[m][i] > (nlstate+ndeath)) {
           (*nberr)++;
           printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
           fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
           return 1;
         }
       }
     }
   
     /*for (i=1; i<=imx; i++){
     for (m=firstpass; (m<lastpass); m++){
        printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
   }
   
   }*/
   
   
     printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
     fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
   
     return (0);
    /* endread:*/
       printf("Exiting calandcheckages: ");
       return (1);
   }
   
   #if defined(_MSC_VER)
   /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
   /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
   //#include "stdafx.h"
   //#include <stdio.h>
   //#include <tchar.h>
   //#include <windows.h>
   //#include <iostream>
   typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
   
   LPFN_ISWOW64PROCESS fnIsWow64Process;
   
   BOOL IsWow64()
   {
           BOOL bIsWow64 = FALSE;
   
           //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
           //  (HANDLE, PBOOL);
   
           //LPFN_ISWOW64PROCESS fnIsWow64Process;
   
           HMODULE module = GetModuleHandle(_T("kernel32"));
           const char funcName[] = "IsWow64Process";
           fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   GetProcAddress(module, funcName);
   
           if (NULL != fnIsWow64Process)
           {
                   if (!fnIsWow64Process(GetCurrentProcess(),
                           &bIsWow64))
                           //throw std::exception("Unknown error");
                           printf("Unknown error\n");
           }
           return bIsWow64 != FALSE;
   }
   #endif
   
   void syscompilerinfo(int logged)
    {
      /* #include "syscompilerinfo.h"*/
      /* command line Intel compiler 32bit windows, XP compatible:*/
      /* /GS /W3 /Gy
         /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
         "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
         "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
         /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
      */ 
      /* 64 bits */
      /*
        /GS /W3 /Gy
        /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
        /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
        /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
        "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
      /* Optimization are useless and O3 is slower than O2 */
      /*
        /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
        /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
        /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
        /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
      */
      /* Link is */ /* /OUT:"visual studio
         2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
         /PDB:"visual studio
         2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
         "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
         "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
         "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
         /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
         /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
         uiAccess='false'"
         /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
         /NOLOGO /TLBID:1
      */
   #if defined __INTEL_COMPILER
   #if defined(__GNUC__)
           struct utsname sysInfo;  /* For Intel on Linux and OS/X */
   #endif
   #elif defined(__GNUC__) 
   #ifndef  __APPLE__
   #include <gnu/libc-version.h>  /* Only on gnu */
   #endif
      struct utsname sysInfo;
      int cross = CROSS;
      if (cross){
              printf("Cross-");
              if(logged) fprintf(ficlog, "Cross-");
      }
   #endif
   
   #include <stdint.h>
   
      printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
   #if defined(__clang__)
      printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");       /* Clang/LLVM. ---------------------------------------------- */
   #endif
   #if defined(__ICC) || defined(__INTEL_COMPILER)
      printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
   #endif
   #if defined(__GNUC__) || defined(__GNUG__)
      printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
   #endif
   #if defined(__HP_cc) || defined(__HP_aCC)
      printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
   #endif
   #if defined(__IBMC__) || defined(__IBMCPP__)
      printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
   #endif
   #if defined(_MSC_VER)
      printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
   #endif
   #if defined(__PGI)
      printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
   #endif
   #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
      printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
   #endif
      printf(" for "); if (logged) fprintf(ficlog, " for ");
      
   // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
   #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
       // Windows (x64 and x86)
      printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
   #elif __unix__ // all unices, not all compilers
       // Unix
      printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
   #elif __linux__
       // linux
      printf("linux ");if(logged) fprintf(ficlog,"linux ");
   #elif __APPLE__
       // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
      printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
   #endif
   
   /*  __MINGW32__   */
   /*  __CYGWIN__   */
   /* __MINGW64__  */
   // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
   /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
   /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
   /* _WIN64  // Defined for applications for Win64. */
   /* _M_X64 // Defined for compilations that target x64 processors. */
   /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
   
   #if UINTPTR_MAX == 0xffffffff
      printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
   #elif UINTPTR_MAX == 0xffffffffffffffff
      printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
   #else
      printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
   #endif
   
   #if defined(__GNUC__)
   # if defined(__GNUC_PATCHLEVEL__)
   #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                               + __GNUC_MINOR__ * 100 \
                               + __GNUC_PATCHLEVEL__)
   # else
   #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                               + __GNUC_MINOR__ * 100)
   # endif
      printf(" using GNU C version %d.\n", __GNUC_VERSION__);
      if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
   
      if (uname(&sysInfo) != -1) {
        printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
            if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
      }
      else
         perror("uname() error");
      //#ifndef __INTEL_COMPILER 
   #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
      printf("GNU libc version: %s\n", gnu_get_libc_version()); 
      if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
   #endif
   #endif
   
      //   void main()
      //   {
   #if defined(_MSC_VER)
      if (IsWow64()){
              printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
              if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
      }
      else{
              printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
              if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
      }
      //      printf("\nPress Enter to continue...");
      //      getchar();
      //   }
   
   #endif
      
   
    }
   
   int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar){
     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
     int i, j, k, i1 ;
     double ftolpl = 1.e-10;
     double age, agebase, agelim;
   
       strcpy(filerespl,"PL_");
       strcat(filerespl,fileresu);
       if((ficrespl=fopen(filerespl,"w"))==NULL) {
         printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
         fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
       }
       printf("Computing period (stable) prevalence: result on file '%s' \n", filerespl);
       fprintf(ficlog,"Computing period (stable) prevalence: result on file '%s' \n", filerespl);
       pstamp(ficrespl);
       fprintf(ficrespl,"# Period (stable) prevalence \n");
       fprintf(ficrespl,"#Age ");
       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
       fprintf(ficrespl,"\n");
     
       /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
   
       agebase=ageminpar;
       agelim=agemaxpar;
   
       i1=pow(2,cptcoveff);
       if (cptcovn < 1){i1=1;}
   
       for(cptcov=1,k=0;cptcov<=i1;cptcov++){
       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
         //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
           k=k+1;
           /* to clean */
           //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
           fprintf(ficrespl,"#******");
           printf("#******");
           fprintf(ficlog,"#******");
           for(j=1;j<=cptcoveff;j++) {
             fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
             printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
             fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
           }
           fprintf(ficrespl,"******\n");
           printf("******\n");
           fprintf(ficlog,"******\n");
   
           fprintf(ficrespl,"#Age ");
           for(j=1;j<=cptcoveff;j++) {
             fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
           }
           for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
           fprintf(ficrespl,"\n");
           
           for (age=agebase; age<=agelim; age++){
           /* for (age=agebase; age<=agebase; age++){ */
             prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);
             fprintf(ficrespl,"%.0f ",age );
             for(j=1;j<=cptcoveff;j++)
               fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
             for(i=1; i<=nlstate;i++)
               fprintf(ficrespl," %.5f", prlim[i][i]);
             fprintf(ficrespl,"\n");
           } /* Age */
           /* was end of cptcod */
       } /* cptcov */
           return 0;
   }
   
   int hPijx(double *p, int bage, int fage){
       /*------------- h Pij x at various ages ------------*/
   
     int stepsize;
     int agelim;
     int hstepm;
     int nhstepm;
     int h, i, i1, j, k;
   
     double agedeb;
     double ***p3mat;
   
       strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
       if((ficrespij=fopen(filerespij,"w"))==NULL) {
         printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
         fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
       }
       printf("Computing pij: result on file '%s' \n", filerespij);
       fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
     
       stepsize=(int) (stepm+YEARM-1)/YEARM;
       /*if (stepm<=24) stepsize=2;*/
   
       agelim=AGESUP;
       hstepm=stepsize*YEARM; /* Every year of age */
       hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
   
       /* hstepm=1;   aff par mois*/
       pstamp(ficrespij);
       fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
       i1= pow(2,cptcoveff);
      /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
      /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
      /*   k=k+1;  */
       for (k=1; k <= (int) pow(2,cptcoveff); k++){
         fprintf(ficrespij,"\n#****** ");
         for(j=1;j<=cptcoveff;j++) 
           fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
         fprintf(ficrespij,"******\n");
         
         for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
           nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
           nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
           
           /*        nhstepm=nhstepm*YEARM; aff par mois*/
           
           p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           oldm=oldms;savm=savms;
           hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
           fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
           for(i=1; i<=nlstate;i++)
             for(j=1; j<=nlstate+ndeath;j++)
               fprintf(ficrespij," %1d-%1d",i,j);
           fprintf(ficrespij,"\n");
           for (h=0; h<=nhstepm; h++){
             /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
             fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
             for(i=1; i<=nlstate;i++)
               for(j=1; j<=nlstate+ndeath;j++)
                 fprintf(ficrespij," %.5f", p3mat[i][j][h]);
             fprintf(ficrespij,"\n");
           }
           free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           fprintf(ficrespij,"\n");
         }
         /*}*/
       }
           return 0;
   }
   
   
   /***********************************************/
   /**************** Main Program *****************/
   /***********************************************/
   
   int main(int argc, char *argv[])
   {
   #ifdef GSL
     const gsl_multimin_fminimizer_type *T;
     size_t iteri = 0, it;
     int rval = GSL_CONTINUE;
     int status = GSL_SUCCESS;
     double ssval;
   #endif
     int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
     int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
   
     int jj, ll, li, lj, lk;
     int numlinepar=0; /* Current linenumber of parameter file */
     int num_filled;
     int itimes;
     int NDIM=2;
     int vpopbased=0;
   
     char ca[32], cb[32];
     /*  FILE *fichtm; *//* Html File */
     /* FILE *ficgp;*/ /*Gnuplot File */
     struct stat info;
     double agedeb=0.;
   
     double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
   
     double fret;
     double dum=0.; /* Dummy variable */
     double ***p3mat;
     double ***mobaverage;
   
     char line[MAXLINE];
     char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
   
     char model[MAXLINE], modeltemp[MAXLINE];
     char pathr[MAXLINE], pathimach[MAXLINE]; 
     char *tok, *val; /* pathtot */
     int firstobs=1, lastobs=10;
     int c,  h , cpt, c2;
     int jl=0;
     int i1, j1, jk, stepsize=0;
     int count=0;
   
     int *tab; 
     int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
     int mobilav=0,popforecast=0;
     int hstepm=0, nhstepm=0;
     int agemortsup;
     float  sumlpop=0.;
     double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
     double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
   
     double bage=0, fage=110., age, agelim=0., agebase=0.;
     double ftolpl=FTOL;
     double **prlim;
     double ***param; /* Matrix of parameters */
     double  *p;
     double **matcov; /* Matrix of covariance */
     double ***delti3; /* Scale */
     double *delti; /* Scale */
     double ***eij, ***vareij;
     double **varpl; /* Variances of prevalence limits by age */
     double *epj, vepp;
   
     double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
     double **ximort;
     char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
     int *dcwave;
   
     char z[1]="c";
   
     /*char  *strt;*/
     char strtend[80];
   
   
   /*   setlocale (LC_ALL, ""); */
   /*   bindtextdomain (PACKAGE, LOCALEDIR); */
   /*   textdomain (PACKAGE); */
   /*   setlocale (LC_CTYPE, ""); */
   /*   setlocale (LC_MESSAGES, ""); */
   
     /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
     rstart_time = time(NULL);  
     /*  (void) gettimeofday(&start_time,&tzp);*/
     start_time = *localtime(&rstart_time);
     curr_time=start_time;
     /*tml = *localtime(&start_time.tm_sec);*/
     /* strcpy(strstart,asctime(&tml)); */
     strcpy(strstart,asctime(&start_time));
   
   /*  printf("Localtime (at start)=%s",strstart); */
   /*  tp.tm_sec = tp.tm_sec +86400; */
   /*  tm = *localtime(&start_time.tm_sec); */
   /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
   /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
   /*   tmg.tm_hour=tmg.tm_hour + 1; */
   /*   tp.tm_sec = mktime(&tmg); */
   /*   strt=asctime(&tmg); */
   /*   printf("Time(after) =%s",strstart);  */
   /*  (void) time (&time_value);
   *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
   *  tm = *localtime(&time_value);
   *  strstart=asctime(&tm);
   *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
   */
   
     nberr=0; /* Number of errors and warnings */
     nbwarn=0;
   #ifdef WIN32
     _getcwd(pathcd, size);
   #else
     getcwd(pathcd, size);
   #endif
     syscompilerinfo(0);
     printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
     if(argc <=1){
       printf("\nEnter the parameter file name: ");
       fgets(pathr,FILENAMELENGTH,stdin);
       i=strlen(pathr);
       if(pathr[i-1]=='\n')
         pathr[i-1]='\0';
       i=strlen(pathr);
       if(pathr[i-1]==' ') /* This may happen when dragging on oS/X! */
         pathr[i-1]='\0';
      for (tok = pathr; tok != NULL; ){
         printf("Pathr |%s|\n",pathr);
         while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
         printf("val= |%s| pathr=%s\n",val,pathr);
         strcpy (pathtot, val);
         if(pathr[0] == '\0') break; /* Dirty */
       }
     }
     else{
       strcpy(pathtot,argv[1]);
     }
     /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
     /*cygwin_split_path(pathtot,path,optionfile);
       printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
     /* cutv(path,optionfile,pathtot,'\\');*/
   
     /* Split argv[0], imach program to get pathimach */
     printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
     split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
     printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
    /*   strcpy(pathimach,argv[0]); */
     /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
     split(pathtot,path,optionfile,optionfilext,optionfilefiname);
     printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
   #ifdef WIN32
     _chdir(path); /* Can be a relative path */
     if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
   #else
     chdir(path); /* Can be a relative path */
     if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
   #endif
     printf("Current directory %s!\n",pathcd);
     strcpy(command,"mkdir ");
     strcat(command,optionfilefiname);
     if((outcmd=system(command)) != 0){
       printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
       /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
       /* fclose(ficlog); */
   /*     exit(1); */
     }
   /*   if((imk=mkdir(optionfilefiname))<0){ */
   /*     perror("mkdir"); */
   /*   } */
   
     /*-------- arguments in the command line --------*/
   
     /* Main Log file */
     strcat(filelog, optionfilefiname);
     strcat(filelog,".log");    /* */
     if((ficlog=fopen(filelog,"w"))==NULL)    {
       printf("Problem with logfile %s\n",filelog);
       goto end;
     }
     fprintf(ficlog,"Log filename:%s\n",filelog);
     fprintf(ficlog,"Version %s %s",version,fullversion);
     fprintf(ficlog,"\nEnter the parameter file name: \n");
     fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
    path=%s \n\
    optionfile=%s\n\
    optionfilext=%s\n\
    optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
   
     syscompilerinfo(1);
   
     printf("Local time (at start):%s",strstart);
     fprintf(ficlog,"Local time (at start): %s",strstart);
     fflush(ficlog);
   /*   (void) gettimeofday(&curr_time,&tzp); */
   /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
   
     /* */
     strcpy(fileres,"r");
     strcat(fileres, optionfilefiname);
     strcat(fileresu, optionfilefiname); /* Without r in front */
     strcat(fileres,".txt");    /* Other files have txt extension */
     strcat(fileresu,".txt");    /* Other files have txt extension */
   
     /* Main ---------arguments file --------*/
   
     if((ficpar=fopen(optionfile,"r"))==NULL)    {
       printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
       fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
       fflush(ficlog);
       /* goto end; */
       exit(70); 
     }
   
   
   
     strcpy(filereso,"o");
     strcat(filereso,fileresu);
     if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
       printf("Problem with Output resultfile: %s\n", filereso);
       fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
       fflush(ficlog);
       goto end;
     }
   
     /* Reads comments: lines beginning with '#' */
     numlinepar=0;
   
       /* First parameter line */
     while(fgets(line, MAXLINE, ficpar)) {
       /* If line starts with a # it is a comment */
       if (line[0] == '#') {
         numlinepar++;
         fputs(line,stdout);
         fputs(line,ficparo);
         fputs(line,ficlog);
         continue;
       }else
         break;
     }
     if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                           title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
       if (num_filled != 5) {
         printf("Should be 5 parameters\n");
       }
       numlinepar++;
       printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
     }
     /* Second parameter line */
     while(fgets(line, MAXLINE, ficpar)) {
       /* If line starts with a # it is a comment */
       if (line[0] == '#') {
         numlinepar++;
         fputs(line,stdout);
         fputs(line,ficparo);
         fputs(line,ficlog);
         continue;
       }else
         break;
     }
     if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                           &ftol, &stepm, &ncovcol, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
       if (num_filled != 8) {
         printf("Not 8\n");
       }
       printf("ftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt);
     }
   
     /* Third parameter line */
     while(fgets(line, MAXLINE, ficpar)) {
       /* If line starts with a # it is a comment */
       if (line[0] == '#') {
         numlinepar++;
         fputs(line,stdout);
         fputs(line,ficparo);
         fputs(line,ficlog);
         continue;
       }else
         break;
     }
     if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
       if (num_filled == 0)
               model[0]='\0';
       else if (num_filled != 1){
         printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
         fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
         model[0]='\0';
         goto end;
       }
       else{
         if (model[0]=='+'){
           for(i=1; i<=strlen(model);i++)
             modeltemp[i-1]=model[i];
           strcpy(model,modeltemp); 
         }
       }
       /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
     }
     /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
     /* numlinepar=numlinepar+3; /\* In general *\/ */
     /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
     if(model[strlen(model)-1]=='.') /* Suppressing leading dot in the model */
       model[strlen(model)-1]='\0';
     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model);
     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model);
     fflush(ficlog);
     /* if(model[0]=='#'|| model[0]== '\0'){ */
     if(model[0]=='#'){
       printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
    'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
    'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");          \
       if(mle != -1){
         printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
         exit(1);
       }
     }
     while((c=getc(ficpar))=='#' && c!= EOF){
       ungetc(c,ficpar);
       fgets(line, MAXLINE, ficpar);
       numlinepar++;
       if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
         z[0]=line[1];
       }
       /* printf("****line [1] = %c \n",line[1]); */
       fputs(line, stdout);
       //puts(line);
       fputs(line,ficparo);
       fputs(line,ficlog);
     }
     ungetc(c,ficpar);
   
      
     covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
     cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
     /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
        v1+v2*age+v2*v3 makes cptcovn = 3
     */
     if (strlen(model)>1) 
       ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
     else
       ncovmodel=2; /* Constant and age */
     nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
     npar= nforce*ncovmodel; /* Number of parameters like aij*/
     if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
       printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
       fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
       fflush(stdout);
       fclose (ficlog);
       goto end;
     }
     delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
     delti=delti3[1][1];
     /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
     if(mle==-1){ /* Print a wizard for help writing covariance matrix */
       prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
       printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
       fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
       free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
       fclose (ficparo);
       fclose (ficlog);
       goto end;
       exit(0);
     }
     else if(mle==-3) { /* Main Wizard */
       prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
       printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
       fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
       param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
       matcov=matrix(1,npar,1,npar);
     }
     else{
       /* Read guessed parameters */
       /* Reads comments: lines beginning with '#' */
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         numlinepar++;
         fputs(line,stdout);
         fputs(line,ficparo);
         fputs(line,ficlog);
       }
       ungetc(c,ficpar);
       
       param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
       for(i=1; i <=nlstate; i++){
         j=0;
         for(jj=1; jj <=nlstate+ndeath; jj++){
           if(jj==i) continue;
           j++;
           fscanf(ficpar,"%1d%1d",&i1,&j1);
           if ((i1 != i) || (j1 != jj)){
             printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
   It might be a problem of design; if ncovcol and the model are correct\n \
   run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
             exit(1);
           }
           fprintf(ficparo,"%1d%1d",i1,j1);
           if(mle==1)
             printf("%1d%1d",i,jj);
           fprintf(ficlog,"%1d%1d",i,jj);
           for(k=1; k<=ncovmodel;k++){
             fscanf(ficpar," %lf",&param[i][j][k]);
             if(mle==1){
               printf(" %lf",param[i][j][k]);
               fprintf(ficlog," %lf",param[i][j][k]);
             }
             else
               fprintf(ficlog," %lf",param[i][j][k]);
             fprintf(ficparo," %lf",param[i][j][k]);
           }
           fscanf(ficpar,"\n");
           numlinepar++;
           if(mle==1)
             printf("\n");
           fprintf(ficlog,"\n");
           fprintf(ficparo,"\n");
         }
       }  
       fflush(ficlog);
   
       /* Reads scales values */
       p=param[1][1];
       
       /* Reads comments: lines beginning with '#' */
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         numlinepar++;
         fputs(line,stdout);
         fputs(line,ficparo);
         fputs(line,ficlog);
       }
       ungetc(c,ficpar);
   
       for(i=1; i <=nlstate; i++){
         for(j=1; j <=nlstate+ndeath-1; j++){
           fscanf(ficpar,"%1d%1d",&i1,&j1);
           if ( (i1-i) * (j1-j) != 0){
             printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
             exit(1);
           }
           printf("%1d%1d",i,j);
           fprintf(ficparo,"%1d%1d",i1,j1);
           fprintf(ficlog,"%1d%1d",i1,j1);
           for(k=1; k<=ncovmodel;k++){
             fscanf(ficpar,"%le",&delti3[i][j][k]);
             printf(" %le",delti3[i][j][k]);
             fprintf(ficparo," %le",delti3[i][j][k]);
             fprintf(ficlog," %le",delti3[i][j][k]);
           }
           fscanf(ficpar,"\n");
           numlinepar++;
           printf("\n");
           fprintf(ficparo,"\n");
           fprintf(ficlog,"\n");
         }
       }
       fflush(ficlog);
   
       /* Reads covariance matrix */
       delti=delti3[1][1];
   
   
       /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
     
       /* Reads comments: lines beginning with '#' */
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         numlinepar++;
         fputs(line,stdout);
         fputs(line,ficparo);
         fputs(line,ficlog);
       }
       ungetc(c,ficpar);
     
       matcov=matrix(1,npar,1,npar);
       for(i=1; i <=npar; i++)
         for(j=1; j <=npar; j++) matcov[i][j]=0.;
         
       /* Scans npar lines */
       for(i=1; i <=npar; i++){
         count=fscanf(ficpar,"%1d%1d%1d",&i1,&j1,&jk);
         if(count != 3){
           printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
   This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
   Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
           fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
   This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
   Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
           exit(1);
         }else
         if(mle==1)
           printf("%1d%1d%1d",i1,j1,jk);
         fprintf(ficlog,"%1d%1d%1d",i1,j1,jk);
         fprintf(ficparo,"%1d%1d%1d",i1,j1,jk);
         for(j=1; j <=i; j++){
           fscanf(ficpar," %le",&matcov[i][j]);
           if(mle==1){
             printf(" %.5le",matcov[i][j]);
           }
           fprintf(ficlog," %.5le",matcov[i][j]);
           fprintf(ficparo," %.5le",matcov[i][j]);
         }
         fscanf(ficpar,"\n");
         numlinepar++;
         if(mle==1)
           printf("\n");
         fprintf(ficlog,"\n");
         fprintf(ficparo,"\n");
       }
       /* End of read covariance matrix npar lines */
       for(i=1; i <=npar; i++)
         for(j=i+1;j<=npar;j++)
           matcov[i][j]=matcov[j][i];
       
       if(mle==1)
         printf("\n");
       fprintf(ficlog,"\n");
       
       fflush(ficlog);
       
       /*-------- Rewriting parameter file ----------*/
       strcpy(rfileres,"r");    /* "Rparameterfile */
       strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
       strcat(rfileres,".");    /* */
       strcat(rfileres,optionfilext);    /* Other files have txt extension */
       if((ficres =fopen(rfileres,"w"))==NULL) {
         printf("Problem writing new parameter file: %s\n", rfileres);goto end;
         fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
       }
       fprintf(ficres,"#%s\n",version);
     }    /* End of mle != -3 */
   
     /*  Main data
      */
     n= lastobs;
     num=lvector(1,n);
     moisnais=vector(1,n);
     annais=vector(1,n);
     moisdc=vector(1,n);
     andc=vector(1,n);
     agedc=vector(1,n);
     cod=ivector(1,n);
     weight=vector(1,n);
     for(i=1;i<=n;i++) weight[i]=1.0; /* Equal weights, 1 by default */
     mint=matrix(1,maxwav,1,n);
     anint=matrix(1,maxwav,1,n);
     s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
     tab=ivector(1,NCOVMAX);
     ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
     ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
   
     /* Reads data from file datafile */
     if (readdata(datafile, firstobs, lastobs, &imx)==1)
       goto end;
   
     /* Calculation of the number of parameters from char model */
       /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
           k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
           k=3 V4 Tvar[k=3]= 4 (from V4)
           k=2 V1 Tvar[k=2]= 1 (from V1)
           k=1 Tvar[1]=2 (from V2)
       */
     Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
     /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
         For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
         Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
     */
     /* For model-covariate k tells which data-covariate to use but
       because this model-covariate is a construction we invent a new column
       ncovcol + k1
       If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
       Tvar[3=V1*V4]=4+1 etc */
     Tprod=ivector(1,NCOVMAX); /* Gives the position of a product */
     /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
        if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
     */
     Tvaraff=ivector(1,NCOVMAX); /* Unclear */
     Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
                               * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                               * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
     Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
                            4 covariates (3 plus signs)
                            Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                         */  
   
   /* Main decodemodel */
   
   
     if(decodemodel(model, lastobs) == 1)
       goto end;
   
     if((double)(lastobs-imx)/(double)imx > 1.10){
       nbwarn++;
       printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
       fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
     }
       /*  if(mle==1){*/
     if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
       for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
     }
   
       /*-calculation of age at interview from date of interview and age at death -*/
     agev=matrix(1,maxwav,1,imx);
   
     if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
       goto end;
   
   
     agegomp=(int)agemin;
     free_vector(moisnais,1,n);
     free_vector(annais,1,n);
     /* free_matrix(mint,1,maxwav,1,n);
        free_matrix(anint,1,maxwav,1,n);*/
     free_vector(moisdc,1,n);
     free_vector(andc,1,n);
     /* */
     
     wav=ivector(1,imx);
     dh=imatrix(1,lastpass-firstpass+1,1,imx);
     bh=imatrix(1,lastpass-firstpass+1,1,imx);
     mw=imatrix(1,lastpass-firstpass+1,1,imx);
      
     /* Concatenates waves */
     concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
     /* */
    
     /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
   
     nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
     ncodemax[1]=1;
     Ndum =ivector(-1,NCOVMAX);  
     if (ncovmodel-nagesqr > 2 ) /* That is if covariate other than cst, age and age*age */
       tricode(Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
     /* Nbcode gives the value of the lth modality of jth covariate, in
        V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
     /* 1 to ncodemax[j] is the maximum value of this jth covariate */
   
     /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
     /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
     /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
     h=0;
   
   
     /*if (cptcovn > 0) */
         
    
     m=pow(2,cptcoveff);
    
             /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
              * For k=4 covariates, h goes from 1 to 2**k
              * codtabm(h,k)=  1 & (h-1) >> (k-1) ;
              *     h\k   1     2     3     4
              *______________________________  
              *     1 i=1 1 i=1 1 i=1 1 i=1 1
              *     2     2     1     1     1
              *     3 i=2 1     2     1     1
              *     4     2     2     1     1
              *     5 i=3 1 i=2 1     2     1
              *     6     2     1     2     1
              *     7 i=4 1     2     2     1
              *     8     2     2     2     1
              *     9 i=5 1 i=3 1 i=2 1     2
              *    10     2     1     1     2
              *    11 i=6 1     2     1     2
              *    12     2     2     1     2
              *    13 i=7 1 i=4 1     2     2    
              *    14     2     1     2     2
              *    15 i=8 1     2     2     2
              *    16     2     2     2     2
              */
     for(h=1; h <=100 ;h++){ 
       /* printf("h=%2d ", h); */
        /* for(k=1; k <=10; k++){ */
          /* printf("k=%d %d ",k,codtabm(h,k)); */
        /*   codtab[h][k]=codtabm(h,k); */
        /* } */
        /* printf("\n"); */
     }
     /* for(k=1;k<=cptcoveff; k++){ /\* scans any effective covariate *\/ */
     /*   for(i=1; i <=pow(2,cptcoveff-k);i++){ /\* i=1 to 8/1=8; i=1 to 8/2=4; i=1 to 8/8=1 *\/  */
     /*     for(j=1; j <= ncodemax[k]; j++){ /\* For each modality of this covariate ncodemax=2*\/ */
     /*    for(cpt=1; cpt <=pow(2,k-1); cpt++){  /\* cpt=1 to 8/2**(3+1-1 or 3+1-3) =1 or 4 *\/  */
     /*      h++; */
     /*      if (h>m)  */
     /*        h=1; */
     /*      codtab[h][k]=j; */
     /*      /\* codtab[12][3]=1; *\/ */
     /*      /\*codtab[h][Tvar[k]]=j;*\/ */
     /*      /\* printf("h=%d k=%d j=%d codtab[h][k]=%d Tvar[k]=%d codtab[h][Tvar[k]]=%d \n",h, k,j,codtab[h][k],Tvar[k],codtab[h][Tvar[k]]); *\/ */
     /*    }  */
     /*     } */
     /*   } */
     /* }  */
     /* printf("codtab[1][2]=%d codtab[2][2]=%d",codtab[1][2],codtab[2][2]); 
        codtab[1][2]=1;codtab[2][2]=2; */
     /* for(i=1; i <=m ;i++){  */
     /*    for(k=1; k <=cptcovn; k++){ */
     /*      printf("i=%d k=%d %d %d ",i,k,codtab[i][k], cptcoveff); */
     /*    } */
     /*    printf("\n"); */
     /* } */
     /*   scanf("%d",i);*/
   
    free_ivector(Ndum,-1,NCOVMAX);
   
   
       
     /* Initialisation of ----------- gnuplot -------------*/
     strcpy(optionfilegnuplot,optionfilefiname);
     if(mle==-3)
       strcat(optionfilegnuplot,"-MORT_");
     strcat(optionfilegnuplot,".gp");
   
     if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
       printf("Problem with file %s",optionfilegnuplot);
     }
     else{
       fprintf(ficgp,"\n# %s\n", version); 
       fprintf(ficgp,"# %s\n", optionfilegnuplot); 
       //fprintf(ficgp,"set missing 'NaNq'\n");
       fprintf(ficgp,"set datafile missing 'NaNq'\n");
     }
     /*  fclose(ficgp);*/
   
   
     /* Initialisation of --------- index.htm --------*/
   
     strcpy(optionfilehtm,optionfilefiname); /* Main html file */
     if(mle==-3)
       strcat(optionfilehtm,"-MORT_");
     strcat(optionfilehtm,".htm");
     if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
       printf("Problem with %s \n",optionfilehtm);
       exit(0);
     }
   
     strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
     strcat(optionfilehtmcov,"-cov.htm");
     if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
       printf("Problem with %s \n",optionfilehtmcov), exit(0);
     }
     else{
     fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
   <hr size=\"2\" color=\"#EC5E5E\"> \n\
   Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=%s<br>\n",\
             optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
     }
   
     fprintf(fichtm,"<html><head>\n<title>IMaCh %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
   <hr size=\"2\" color=\"#EC5E5E\"> \n\
   Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=%s<br>\n\
   \n\
   <hr  size=\"2\" color=\"#EC5E5E\">\
    <ul><li><h4>Parameter files</h4>\n\
    - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
    - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
    - Log file of the run: <a href=\"%s\">%s</a><br>\n\
    - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
    - Date and time at start: %s</ul>\n",\
             optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
             optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
             fileres,fileres,\
             filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
     fflush(fichtm);
   
     strcpy(pathr,path);
     strcat(pathr,optionfilefiname);
   #ifdef WIN32
     _chdir(optionfilefiname); /* Move to directory named optionfile */
   #else
     chdir(optionfilefiname); /* Move to directory named optionfile */
   #endif
             
     
     /* Calculates basic frequencies. Computes observed prevalence at single age
        and prints on file fileres'p'. */
     freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart);
   
     fprintf(fichtm,"\n");
     fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
   Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
   Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
             imx,agemin,agemax,jmin,jmax,jmean);
     pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
       
      
     /* For Powell, parameters are in a vector p[] starting at p[1]
        so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
     p=param[1][1]; /* *(*(*(param +1)+1)+0) */
   
     globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
     /* For mortality only */
     if (mle==-3){
       ximort=matrix(1,NDIM,1,NDIM); 
       /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
       cens=ivector(1,n);
       ageexmed=vector(1,n);
       agecens=vector(1,n);
       dcwave=ivector(1,n);
    
       for (i=1; i<=imx; i++){
         dcwave[i]=-1;
         for (m=firstpass; m<=lastpass; m++)
           if (s[m][i]>nlstate) {
             dcwave[i]=m;
             /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
             break;
           }
       }
   
       for (i=1; i<=imx; i++) {
         if (wav[i]>0){
           ageexmed[i]=agev[mw[1][i]][i];
           j=wav[i];
           agecens[i]=1.; 
   
           if (ageexmed[i]> 1 && wav[i] > 0){
             agecens[i]=agev[mw[j][i]][i];
             cens[i]= 1;
           }else if (ageexmed[i]< 1) 
             cens[i]= -1;
           if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
             cens[i]=0 ;
         }
         else cens[i]=-1;
       }
       
       for (i=1;i<=NDIM;i++) {
         for (j=1;j<=NDIM;j++)
           ximort[i][j]=(i == j ? 1.0 : 0.0);
       }
       
       /*p[1]=0.0268; p[NDIM]=0.083;*/
       /*printf("%lf %lf", p[1], p[2]);*/
       
       
   #ifdef GSL
       printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
   #else
       printf("Powell\n");  fprintf(ficlog,"Powell\n");
   #endif
       strcpy(filerespow,"POW-MORT_"); 
       strcat(filerespow,fileresu);
       if((ficrespow=fopen(filerespow,"w"))==NULL) {
         printf("Problem with resultfile: %s\n", filerespow);
         fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
       }
   #ifdef GSL
       fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
   #else
       fprintf(ficrespow,"# Powell\n# iter -2*LL");
   #endif
       /*  for (i=1;i<=nlstate;i++)
           for(j=1;j<=nlstate+ndeath;j++)
           if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
       */
       fprintf(ficrespow,"\n");
   #ifdef GSL
       /* gsl starts here */ 
       T = gsl_multimin_fminimizer_nmsimplex;
       gsl_multimin_fminimizer *sfm = NULL;
       gsl_vector *ss, *x;
       gsl_multimin_function minex_func;
   
       /* Initial vertex size vector */
       ss = gsl_vector_alloc (NDIM);
       
       if (ss == NULL){
         GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
       }
       /* Set all step sizes to 1 */
       gsl_vector_set_all (ss, 0.001);
   
       /* Starting point */
       
       x = gsl_vector_alloc (NDIM);
       
       if (x == NULL){
         gsl_vector_free(ss);
         GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
       }
     
       /* Initialize method and iterate */
       /*     p[1]=0.0268; p[NDIM]=0.083; */
       /*     gsl_vector_set(x, 0, 0.0268); */
       /*     gsl_vector_set(x, 1, 0.083); */
       gsl_vector_set(x, 0, p[1]);
       gsl_vector_set(x, 1, p[2]);
   
       minex_func.f = &gompertz_f;
       minex_func.n = NDIM;
       minex_func.params = (void *)&p; /* ??? */
       
       sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
       gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
       
       printf("Iterations beginning .....\n\n");
       printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
   
       iteri=0;
       while (rval == GSL_CONTINUE){
         iteri++;
         status = gsl_multimin_fminimizer_iterate(sfm);
         
         if (status) printf("error: %s\n", gsl_strerror (status));
         fflush(0);
         
         if (status) 
           break;
         
         rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
         ssval = gsl_multimin_fminimizer_size (sfm);
         
         if (rval == GSL_SUCCESS)
           printf ("converged to a local maximum at\n");
         
         printf("%5d ", iteri);
         for (it = 0; it < NDIM; it++){
           printf ("%10.5f ", gsl_vector_get (sfm->x, it));
         }
         printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
       }
       
       printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
       
       gsl_vector_free(x); /* initial values */
       gsl_vector_free(ss); /* inital step size */
       for (it=0; it<NDIM; it++){
         p[it+1]=gsl_vector_get(sfm->x,it);
         fprintf(ficrespow," %.12lf", p[it]);
       }
       gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
   #endif
   #ifdef POWELL
        powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
   #endif  
       fclose(ficrespow);
       
       hesscov(matcov, p, NDIM, delti, 1e-4, gompertz); 
   
       for(i=1; i <=NDIM; i++)
         for(j=i+1;j<=NDIM;j++)
           matcov[i][j]=matcov[j][i];
       
       printf("\nCovariance matrix\n ");
       for(i=1; i <=NDIM; i++) {
         for(j=1;j<=NDIM;j++){ 
           printf("%f ",matcov[i][j]);
         }
         printf("\n ");
       }
       
       printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
       for (i=1;i<=NDIM;i++) {
         printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
         fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
       }
       lsurv=vector(1,AGESUP);
       lpop=vector(1,AGESUP);
       tpop=vector(1,AGESUP);
       lsurv[agegomp]=100000;
       
       for (k=agegomp;k<=AGESUP;k++) {
         agemortsup=k;
         if (p[1]*exp(p[2]*(k-agegomp))>1) break;
       }
       
       for (k=agegomp;k<agemortsup;k++)
         lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
       
       for (k=agegomp;k<agemortsup;k++){
         lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
         sumlpop=sumlpop+lpop[k];
       }
       
       tpop[agegomp]=sumlpop;
       for (k=agegomp;k<(agemortsup-3);k++){
         /*  tpop[k+1]=2;*/
         tpop[k+1]=tpop[k]-lpop[k];
       }
       
       
       printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
       for (k=agegomp;k<(agemortsup-2);k++) 
         printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
       
       
       replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
       if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
           printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
   This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
   Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
           fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
   This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
   Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
       }else
         printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
       printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
                        stepm, weightopt,\
                        model,imx,p,matcov,agemortsup);
       
       free_vector(lsurv,1,AGESUP);
       free_vector(lpop,1,AGESUP);
       free_vector(tpop,1,AGESUP);
   #ifdef GSL
       free_ivector(cens,1,n);
       free_vector(agecens,1,n);
       free_ivector(dcwave,1,n);
       free_matrix(ximort,1,NDIM,1,NDIM);
   #endif
     } /* Endof if mle==-3 mortality only */
     /* Standard maximisation */
     else{ /* For mle >=1 */
       globpr=0;/* debug */
       /* Computes likelihood for initial parameters */
       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
       printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
       for (k=1; k<=npar;k++)
         printf(" %d %8.5f",k,p[k]);
       printf("\n");
       globpr=1; /* again, to print the contributions */
       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
       printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
       for (k=1; k<=npar;k++)
         printf(" %d %8.5f",k,p[k]);
       printf("\n");
       if(mle>=1){ /* Could be 1 or 2, Real Maximisation */
         mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
       }
       
       /*--------- results files --------------*/
       fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate, ndeath, maxwav, weightopt,model);
       
       
       fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
       printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
       fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
       for(i=1,jk=1; i <=nlstate; i++){
         for(k=1; k <=(nlstate+ndeath); k++){
           if (k != i) {
             printf("%d%d ",i,k);
             fprintf(ficlog,"%d%d ",i,k);
             fprintf(ficres,"%1d%1d ",i,k);
             for(j=1; j <=ncovmodel; j++){
               printf("%12.7f ",p[jk]);
               fprintf(ficlog,"%12.7f ",p[jk]);
               fprintf(ficres,"%12.7f ",p[jk]);
               jk++; 
             }
             printf("\n");
             fprintf(ficlog,"\n");
             fprintf(ficres,"\n");
           }
         }
       }
       if(mle!=0){
         /* Computing hessian and covariance matrix */
         ftolhess=ftol; /* Usually correct */
         hesscov(matcov, p, npar, delti, ftolhess, func);
       }
       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
       for(i=1,jk=1; i <=nlstate; i++){
         for(k=1; k <=(nlstate+ndeath); k++){
           if (k != i) {
             printf("%d%d ",i,k);
             fprintf(ficlog,"%d%d ",i,k);
             for(j=1; j <=ncovmodel; j++){
               printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
               fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
               jk++; 
             }
             printf("\n");
             fprintf(ficlog,"\n");
           }
         }
       }
   
       fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
       printf("# Scales (for hessian or gradient estimation)\n");
       fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
       for(i=1,jk=1; i <=nlstate; i++){
         for(j=1; j <=nlstate+ndeath; j++){
           if (j!=i) {
             fprintf(ficres,"%1d%1d",i,j);
             printf("%1d%1d",i,j);
             fprintf(ficlog,"%1d%1d",i,j);
             for(k=1; k<=ncovmodel;k++){
               printf(" %.5e",delti[jk]);
               fprintf(ficlog," %.5e",delti[jk]);
               fprintf(ficres," %.5e",delti[jk]);
               jk++;
             }
             printf("\n");
             fprintf(ficlog,"\n");
             fprintf(ficres,"\n");
           }
         }
       }
       
       fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
       if(mle>=1)
         printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
       fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
       /* # 121 Var(a12)\n\ */
       /* # 122 Cov(b12,a12) Var(b12)\n\ */
       /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
       /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
       /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
       /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
       /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
       /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
       
       
       /* Just to have a covariance matrix which will be more understandable
          even is we still don't want to manage dictionary of variables
       */
       for(itimes=1;itimes<=2;itimes++){
         jj=0;
         for(i=1; i <=nlstate; i++){
           for(j=1; j <=nlstate+ndeath; j++){
             if(j==i) continue;
             for(k=1; k<=ncovmodel;k++){
               jj++;
               ca[0]= k+'a'-1;ca[1]='\0';
               if(itimes==1){
                 if(mle>=1)
                   printf("#%1d%1d%d",i,j,k);
                 fprintf(ficlog,"#%1d%1d%d",i,j,k);
                 fprintf(ficres,"#%1d%1d%d",i,j,k);
               }else{
                 if(mle>=1)
                   printf("%1d%1d%d",i,j,k);
                 fprintf(ficlog,"%1d%1d%d",i,j,k);
                 fprintf(ficres,"%1d%1d%d",i,j,k);
               }
               ll=0;
               for(li=1;li <=nlstate; li++){
                 for(lj=1;lj <=nlstate+ndeath; lj++){
                   if(lj==li) continue;
                   for(lk=1;lk<=ncovmodel;lk++){
                     ll++;
                     if(ll<=jj){
                       cb[0]= lk +'a'-1;cb[1]='\0';
                       if(ll<jj){
                         if(itimes==1){
                           if(mle>=1)
                             printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                           fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                           fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                         }else{
                           if(mle>=1)
                             printf(" %.5e",matcov[jj][ll]); 
                           fprintf(ficlog," %.5e",matcov[jj][ll]); 
                           fprintf(ficres," %.5e",matcov[jj][ll]); 
                         }
                       }else{
                         if(itimes==1){
                           if(mle>=1)
                             printf(" Var(%s%1d%1d)",ca,i,j);
                           fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                           fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                         }else{
                           if(mle>=1)
                             printf(" %.5e",matcov[jj][ll]); 
                           fprintf(ficlog," %.5e",matcov[jj][ll]); 
                           fprintf(ficres," %.5e",matcov[jj][ll]); 
                         }
                       }
                     }
                   } /* end lk */
                 } /* end lj */
               } /* end li */
               if(mle>=1)
                 printf("\n");
               fprintf(ficlog,"\n");
               fprintf(ficres,"\n");
               numlinepar++;
             } /* end k*/
           } /*end j */
         } /* end i */
       } /* end itimes */
       
       fflush(ficlog);
       fflush(ficres);
       
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         fputs(line,stdout);
         fputs(line,ficparo);
       }
       ungetc(c,ficpar);
       
       estepm=0;
       fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm);
       if (estepm==0 || estepm < stepm) estepm=stepm;
       if (fage <= 2) {
         bage = ageminpar;
         fage = agemaxpar;
       }
       
       fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
       fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d\n",ageminpar,agemaxpar,bage,fage, estepm);
       fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d\n",ageminpar,agemaxpar,bage,fage, estepm);
   
       /* Other stuffs, more or less useful */    
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         fputs(line,stdout);
         fputs(line,ficparo);
       }
       ungetc(c,ficpar);
       
       fscanf(ficpar,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav);
       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
       
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         fputs(line,stdout);
         fputs(line,ficparo);
       }
       ungetc(c,ficpar);
       
       
       dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
       dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
       
       fscanf(ficpar,"pop_based=%d\n",&popbased);
       fprintf(ficlog,"pop_based=%d\n",popbased);
       fprintf(ficparo,"pop_based=%d\n",popbased);   
       fprintf(ficres,"pop_based=%d\n",popbased);   
       
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         fputs(line,stdout);
         fputs(line,ficparo);
       }
       ungetc(c,ficpar);
       
       fscanf(ficpar,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj);
       fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
       printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
       fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
       fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
       /* day and month of proj2 are not used but only year anproj2.*/
       
       
       
        /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
       /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
       
       replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
       if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
           printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
   This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
   Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
           fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
   This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
   Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
       }else
         printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
       
       printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt,\
                    model,imx,jmin,jmax,jmean,rfileres,popforecast,estepm,\
                    jprev1,mprev1,anprev1,jprev2,mprev2,anprev2);
         
      /*------------ free_vector  -------------*/
      /*  chdir(path); */
    
       free_ivector(wav,1,imx);
       free_imatrix(dh,1,lastpass-firstpass+1,1,imx);
       free_imatrix(bh,1,lastpass-firstpass+1,1,imx);
       free_imatrix(mw,1,lastpass-firstpass+1,1,imx);   
       free_lvector(num,1,n);
       free_vector(agedc,1,n);
       /*free_matrix(covar,0,NCOVMAX,1,n);*/
       /*free_matrix(covar,1,NCOVMAX,1,n);*/
       fclose(ficparo);
       fclose(ficres);
   
   
       /* Other results (useful)*/
   
   
       /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
       /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
       prlim=matrix(1,nlstate,1,nlstate);
       prevalence_limit(p, prlim,  ageminpar, agemaxpar);
       fclose(ficrespl);
   
   #ifdef FREEEXIT2
   #include "freeexit2.h"
   #endif
   
       /*------------- h Pij x at various ages ------------*/
       /*#include "hpijx.h"*/
       hPijx(p, bage, fage);
       fclose(ficrespij);
   
     /*-------------- Variance of one-step probabilities---*/
       k=1;
       varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
   
   
       probs= ma3x(1,AGESUP,1,NCOVMAX, 1,NCOVMAX);
       for(i=1;i<=AGESUP;i++)
         for(j=1;j<=NCOVMAX;j++)
           for(k=1;k<=NCOVMAX;k++)
             probs[i][j][k]=0.;
   
       /*---------- Forecasting ------------------*/
       /*if((stepm == 1) && (strcmp(model,".")==0)){*/
       if(prevfcast==1){
         /*    if(stepm ==1){*/
         prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
         /* (popforecast==1) populforecast(fileres, anpyram,mpyram,jpyram, agemin,agemax, dateprev1, dateprev2,mobilav, agedeb, fage, popforecast, popfile, anpyram1,p, i1);*/
         /*      }  */
         /*      else{ */
         /*        erreur=108; */
         /*        printf("Warning %d!! You can only forecast the prevalences if the optimization\n  has been performed with stepm = 1 (month) instead of %d or model=. instead of '%s'\n", erreur, stepm, model); */
         /*        fprintf(ficlog,"Warning %d!! You can only forecast the prevalences if the optimization\n  has been performed with stepm = 1 (month) instead of %d or model=. instead of '%s'\n", erreur, stepm, model); */
         /*      } */
       }
    
       /* ------ Other prevalence ratios------------ */
   
       /* Computes prevalence between agemin (i.e minimal age computed) and no more ageminpar */
   
       prevalence(probs, agemin, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
       /*  printf("ageminpar=%f, agemax=%f, s[lastpass][imx]=%d, agev[lastpass][imx]=%f, nlstate=%d, imx=%d,  mint[lastpass][imx]=%f, anint[lastpass][imx]=%f,dateprev1=%f, dateprev2=%f, firstpass=%d, lastpass=%d\n",\
           ageminpar, agemax, s[lastpass][imx], agev[lastpass][imx], nlstate, imx, mint[lastpass][imx],anint[lastpass][imx], dateprev1, dateprev2, firstpass, lastpass);
       */
   
       if (mobilav!=0) {
         mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
         if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){
           fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
           printf(" Error in movingaverage mobilav=%d\n",mobilav);
         }
       }
   
   
       /*---------- Health expectancies, no variances ------------*/
   
       strcpy(filerese,"E_");
       strcat(filerese,fileresu);
       if((ficreseij=fopen(filerese,"w"))==NULL) {
         printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
         fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
       }
       printf("Computing Health Expectancies: result on file '%s' \n", filerese);
       fprintf(ficlog,"Computing Health Expectancies: result on file '%s' \n", filerese);
       /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
         for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
             
       for (k=1; k <= (int) pow(2,cptcoveff); k++){
           fprintf(ficreseij,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) {
             fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
           }
           fprintf(ficreseij,"******\n");
   
           eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
           oldm=oldms;savm=savms;
           evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart);  
         
           free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
         /*}*/
       }
       fclose(ficreseij);
   
   
       /*---------- Health expectancies and variances ------------*/
   
   
       strcpy(filerest,"T_");
       strcat(filerest,fileresu);
       if((ficrest=fopen(filerest,"w"))==NULL) {
         printf("Problem with total LE resultfile: %s\n", filerest);goto end;
         fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
       }
       printf("Computing Total Life expectancies with their standard errors: file '%s' \n", filerest); 
       fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' \n", filerest); 
   
   
       strcpy(fileresstde,"STDE_");
       strcat(fileresstde,fileresu);
       if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
         printf("Problem with Health Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
         fprintf(ficlog,"Problem with Health Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
       }
       printf("Computing Health Expectancies and standard errors: result on file '%s' \n", fileresstde);
       fprintf(ficlog,"Computing Health Expectancies and standard errors: result on file '%s' \n", fileresstde);
   
       strcpy(filerescve,"CVE_");
       strcat(filerescve,fileresu);
       if((ficrescveij=fopen(filerescve,"w"))==NULL) {
         printf("Problem with Covar. Health Exp. resultfile: %s\n", filerescve); exit(0);
         fprintf(ficlog,"Problem with Covar. Health Exp. resultfile: %s\n", filerescve); exit(0);
       }
       printf("Computing Covar. of Health Expectancies: result on file '%s' \n", filerescve);
       fprintf(ficlog,"Computing Covar. of Health Expectancies: result on file '%s' \n", filerescve);
   
       strcpy(fileresv,"V_");
       strcat(fileresv,fileresu);
       if((ficresvij=fopen(fileresv,"w"))==NULL) {
         printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
         fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
       }
       printf("Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);
       fprintf(ficlog,"Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);
   
       /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
         for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
             
       for (k=1; k <= (int) pow(2,cptcoveff); k++){
           fprintf(ficrest,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) 
             fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
           fprintf(ficrest,"******\n");
   
           fprintf(ficresstdeij,"\n#****** ");
           fprintf(ficrescveij,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) {
             fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
             fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
           }
           fprintf(ficresstdeij,"******\n");
           fprintf(ficrescveij,"******\n");
   
           fprintf(ficresvij,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) 
             fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
           fprintf(ficresvij,"******\n");
   
           eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
           oldm=oldms;savm=savms;
           cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart);  
           /*
            */
           /* goto endfree; */
    
           vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
           pstamp(ficrest);
   
   
           for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
             oldm=oldms;savm=savms; /* ZZ Segmentation fault */
             cptcod= 0; /* To be deleted */
             varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart); /* cptcod not initialized Intel */
             fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
             if(vpopbased==1)
               fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
             else
               fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
             fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
             for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
             fprintf(ficrest,"\n");
             /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
             epj=vector(1,nlstate+1);
             for(age=bage; age <=fage ;age++){
               prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k); /*ZZ Is it the correct prevalim */
               if (vpopbased==1) {
                 if(mobilav ==0){
                   for(i=1; i<=nlstate;i++)
                     prlim[i][i]=probs[(int)age][i][k];
                 }else{ /* mobilav */ 
                   for(i=1; i<=nlstate;i++)
                     prlim[i][i]=mobaverage[(int)age][i][k];
                 }
               }
           
               fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
               /* printf(" age %4.0f ",age); */
               for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                 for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                 }
                 epj[nlstate+1] +=epj[j];
               }
               /* printf(" age %4.0f \n",age); */
   
               for(i=1, vepp=0.;i <=nlstate;i++)
                 for(j=1;j <=nlstate;j++)
                   vepp += vareij[i][j][(int)age];
               fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
               for(j=1;j <=nlstate;j++){
                 fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
               }
               fprintf(ficrest,"\n");
             }
           }
           free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
           free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
           free_vector(epj,1,nlstate+1);
         /*}*/
       }
       free_vector(weight,1,n);
       free_imatrix(Tvard,1,NCOVMAX,1,2);
       free_imatrix(s,1,maxwav+1,1,n);
       free_matrix(anint,1,maxwav,1,n); 
       free_matrix(mint,1,maxwav,1,n);
       free_ivector(cod,1,n);
       free_ivector(tab,1,NCOVMAX);
       fclose(ficresstdeij);
       fclose(ficrescveij);
       fclose(ficresvij);
       fclose(ficrest);
       fclose(ficpar);
     
       /*------- Variance of period (stable) prevalence------*/   
   
       strcpy(fileresvpl,"VPL_");
       strcat(fileresvpl,fileresu);
       if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
         printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
         exit(0);
       }
       printf("Computing Variance-covariance of period (stable) prevalence: file '%s' \n", fileresvpl);
   
       /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
         for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
             
       for (k=1; k <= (int) pow(2,cptcoveff); k++){
           fprintf(ficresvpl,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) 
             fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
           fprintf(ficresvpl,"******\n");
         
           varpl=matrix(1,nlstate,(int) bage, (int) fage);
           oldm=oldms;savm=savms;
           varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k,strstart);
           free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
         /*}*/
       }
   
       fclose(ficresvpl);
   
       /*---------- End : free ----------------*/
       if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       free_ma3x(probs,1,AGESUP,1,NCOVMAX, 1,NCOVMAX);
     }  /* mle==-3 arrives here for freeing */
    /* endfree:*/
       free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
       free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
       free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
       free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
       free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
       free_matrix(covar,0,NCOVMAX,1,n);
       free_matrix(matcov,1,npar,1,npar);
       /*free_vector(delti,1,npar);*/
       free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
       free_matrix(agev,1,maxwav,1,imx);
       free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
   
       free_ivector(ncodemax,1,NCOVMAX);
       free_ivector(ncodemaxwundef,1,NCOVMAX);
       free_ivector(Tvar,1,NCOVMAX);
       free_ivector(Tprod,1,NCOVMAX);
       free_ivector(Tvaraff,1,NCOVMAX);
       free_ivector(Tage,1,NCOVMAX);
   
       free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
       /* free_imatrix(codtab,1,100,1,10); */
     fflush(fichtm);
     fflush(ficgp);
     
   
     if((nberr >0) || (nbwarn>0)){
       printf("End of Imach with %d errors and/or %d warnings\n",nberr,nbwarn);
       fprintf(ficlog,"End of Imach with %d errors and/or warnings %d\n",nberr,nbwarn);
     }else{
       printf("End of Imach\n");
       fprintf(ficlog,"End of Imach\n");
     }
     printf("See log file on %s\n",filelog);
     /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
     /*(void) gettimeofday(&end_time,&tzp);*/
     rend_time = time(NULL);  
     end_time = *localtime(&rend_time);
     /* tml = *localtime(&end_time.tm_sec); */
     strcpy(strtend,asctime(&end_time));
     printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
     fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
     printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
   
     printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
     fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
     fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
     /*  printf("Total time was %d uSec.\n", total_usecs);*/
   /*   if(fileappend(fichtm,optionfilehtm)){ */
     fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
     fclose(fichtm);
     fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
     fclose(fichtmcov);
     fclose(ficgp);
     fclose(ficlog);
     /*------ End -----------*/
   
   
      printf("Before Current directory %s!\n",pathcd);
   #ifdef WIN32
      if (_chdir(pathcd) != 0)
              printf("Can't move to directory %s!\n",path);
      if(_getcwd(pathcd,MAXLINE) > 0)
   #else
      if(chdir(pathcd) != 0)
              printf("Can't move to directory %s!\n", path);
      if (getcwd(pathcd, MAXLINE) > 0)
   #endif 
       printf("Current directory %s!\n",pathcd);
     /*strcat(plotcmd,CHARSEPARATOR);*/
     sprintf(plotcmd,"gnuplot");
   #ifdef _WIN32
     sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
   #endif
     if(!stat(plotcmd,&info)){
       printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
       if(!stat(getenv("GNUPLOTBIN"),&info)){
         printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
       }else
         strcpy(pplotcmd,plotcmd);
   #ifdef __unix
       strcpy(plotcmd,GNUPLOTPROGRAM);
       if(!stat(plotcmd,&info)){
         printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
       }else
         strcpy(pplotcmd,plotcmd);
   #endif
     }else
       strcpy(pplotcmd,plotcmd);
     
     sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
     printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
   
     if((outcmd=system(plotcmd)) != 0){
       printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
       printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
       sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
       if((outcmd=system(plotcmd)) != 0)
         printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
     }
     printf(" Successful, please wait...");
     while (z[0] != 'q') {
       /* chdir(path); */
       printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
       scanf("%s",z);
   /*     if (z[0] == 'c') system("./imach"); */
       if (z[0] == 'e') {
   #ifdef __APPLE__
         sprintf(pplotcmd, "open %s", optionfilehtm);
   #elif __linux
         sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
   #else
         sprintf(pplotcmd, "%s", optionfilehtm);
   #endif
         printf("Starting browser with: %s",pplotcmd);fflush(stdout);
         system(pplotcmd);
       }
       else if (z[0] == 'g') system(plotcmd);
       else if (z[0] == 'q') exit(0);
     }
     end:
     while (z[0] != 'q') {
       printf("\nType  q for exiting: "); fflush(stdout);
       scanf("%s",z);
     }
   }

Removed from v.1.51  
changed lines
  Added in v.1.201


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