--- imach/src/imach.c 2016/02/15 23:22:02 1.220 +++ imach/src/imach.c 2016/07/01 13:16:01 1.224 @@ -1,8 +1,17 @@ -/* $Id: imach.c,v 1.220 2016/02/15 23:22:02 brouard Exp $ +/* $Id: imach.c,v 1.224 2016/07/01 13:16:01 brouard Exp $ $State: Exp $ $Log: imach.c,v $ - Revision 1.220 2016/02/15 23:22:02 brouard - Summary: 0.99r2 + Revision 1.224 2016/07/01 13:16:01 brouard + Summary: Fixes + + Revision 1.223 2016/02/19 09:23:35 brouard + Summary: temporary + + Revision 1.222 2016/02/17 08:14:50 brouard + Summary: Probably last 0.98 stable version 0.98r6 + + Revision 1.221 2016/02/15 23:35:36 brouard + Summary: minor bug Revision 1.219 2016/02/15 00:48:12 brouard *** empty log message *** @@ -739,9 +748,9 @@ Back prevalence and projections: /* #define DEBUGLINMIN */ /* #define DEBUGHESS */ #define DEBUGHESSIJ -#define LINMINORIGINAL /* Don't use loop on scale in linmin (accepting nan)*/ +/* #define LINMINORIGINAL /\* Don't use loop on scale in linmin (accepting nan) *\/ */ #define POWELL /* Instead of NLOPT */ -#define POWELLF1F3 /* Skip test */ +#define POWELLNOF3INFF1TEST /* Skip test */ /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */ /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */ @@ -831,12 +840,12 @@ typedef struct { #define ODIRSEPARATOR '\\' #endif -/* $Id: imach.c,v 1.220 2016/02/15 23:22:02 brouard Exp $ */ +/* $Id: imach.c,v 1.224 2016/07/01 13:16:01 brouard Exp $ */ /* $State: Exp $ */ #include "version.h" char version[]=__IMACH_VERSION__; -char copyright[]="October 2015,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015"; -char fullversion[]="$Revision: 1.220 $ $Date: 2016/02/15 23:22:02 $"; +char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018"; +char fullversion[]="$Revision: 1.224 $ $Date: 2016/07/01 13:16:01 $"; char strstart[80]; char optionfilext[10], optionfilefiname[FILENAMELENGTH]; int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings */ @@ -848,12 +857,17 @@ int cptcovs=0; /**< cptcovs number of si int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */ int cptcovprodnoage=0; /**< Number of covariate products without age */ int cptcoveff=0; /* Total number of covariates to vary for printing results */ +int ncoveff=0; /* Total number of effective covariates in the model */ +int nqveff=0; /**< nqveff number of effective quantitative variables */ +int ntveff=0; /**< ntveff number of effective time varying variables */ +int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */ int cptcov=0; /* Working variable */ int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */ int npar=NPARMAX; int nlstate=2; /* Number of live states */ int ndeath=1; /* Number of dead states */ int ncovmodel=0, ncovcol=0; /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */ +int nqv=0, ntv=0, nqtv=0; /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ int popbased=0; int *wav; /* Number of waves for this individuual 0 is possible */ @@ -992,6 +1006,9 @@ double *agedc; double **covar; /**< covar[j,i], value of jth covariate for individual i, * covar=matrix(0,NCOVMAX,1,n); * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */ +double **coqvar; /* Fixed quantitative covariate */ +double ***cotvar; /* Time varying covariate */ +double ***cotqvar; /* Time varying quantitative covariate */ double idx; int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */ int *Tage; @@ -1539,12 +1556,12 @@ double brent(double ax, double bx, doubl etemp=e; e=d; if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) - d=CGOLD*(e=(x >= xm ? a-x : b-x)); + d=CGOLD*(e=(x >= xm ? a-x : b-x)); else { - d=p/q; - u=x+d; - if (u-a < tol2 || b-u < tol2) - d=SIGN(tol1,xm-x); + d=p/q; + u=x+d; + if (u-a < tol2 || b-u < tol2) + d=SIGN(tol1,xm-x); } } else { d=CGOLD*(e=(x >= xm ? a-x : b-x)); @@ -1558,13 +1575,13 @@ double brent(double ax, double bx, doubl } else { if (u < x) a=u; else b=u; if (fu <= fw || w == x) { - v=w; - w=u; - fv=fw; - fw=fu; + v=w; + w=u; + fv=fw; + fw=fu; } else if (fu <= fv || v == x || v == w) { - v=u; - fv=fu; + v=u; + fv=fu; } } } @@ -1605,12 +1622,12 @@ values at the three points, fa, fb , and *cx=(*bx)+GOLD*(*bx-*ax); *fc=(*func)(*cx); #ifdef DEBUG - printf("mnbrak0 *fb=%.12e *fc=%.12e\n",*fb,*fc); - fprintf(ficlog,"mnbrak0 *fb=%.12e *fc=%.12e\n",*fb,*fc); + printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc); + fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc); #endif - while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc */ + while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/ r=(*bx-*ax)*(*fb-*fc); - q=(*bx-*cx)*(*fb-*fa); + q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */ u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */ ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */ @@ -1621,8 +1638,8 @@ values at the three points, fa, fb , and double A, fparabu; A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u); fparabu= *fa - A*(*ax-u)*(*ax-u); - printf("mnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf), (*u=%.12f, fu=%.12lf, fparabu=%.12f)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu); - fprintf(ficlog, "mnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf), (*u=%.12f, fu=%.12lf, fparabu=%.12f)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu); + printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf), (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r); + fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf), (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r); /* And thus,it can be that fu > *fc even if fparabu < *fc */ /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489), (*cx=10.098840694817, *fc=298946.631474258087), (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */ @@ -1655,9 +1672,12 @@ values at the three points, fa, fb , and /* fu = *fc; */ /* *fc =dum; */ /* } */ -#ifdef DEBUG - printf("mnbrak34 fu < or >= fc \n"); - fprintf(ficlog, "mnbrak34 fu < fc\n"); +#ifdef DEBUGMNBRAK + double A, fparabu; + A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u); + fparabu= *fa - A*(*ax-u)*(*ax-u); + printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r); + fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r); #endif dum=u; /* Shifting c and u */ u = *cx; @@ -1668,38 +1688,45 @@ values at the three points, fa, fb , and #endif } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */ #ifdef DEBUG - printf("mnbrak2 u after c but before ulim\n"); - fprintf(ficlog, "mnbrak2 u after c but before ulim\n"); + printf("\nmnbrak2 u=%lf after c=%lf but before ulim\n",u,*cx); + fprintf(ficlog,"\nmnbrak2 u=%lf after c=%lf but before ulim\n",u,*cx); #endif fu=(*func)(u); if (fu < *fc) { #ifdef DEBUG - printf("mnbrak2 u after c but before ulim AND fu < fc\n"); - fprintf(ficlog, "mnbrak2 u after c but before ulim AND fu = 0.0) { /* u outside ulim (verifying that ulim is beyond c) */ #ifdef DEBUG - printf("mnbrak2 u outside ulim (verifying that ulim is beyond c)\n"); - fprintf(ficlog, "mnbrak2 u outside ulim (verifying that ulim is beyond c)\n"); + printf("\nmnbrak2 u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx); + fprintf(ficlog,"\nmnbrak2 u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx); #endif u=ulim; fu=(*func)(u); } else { /* u could be left to b (if r > q parabola has a maximum) */ #ifdef DEBUG - printf("mnbrak2 u could be left to b (if r > q parabola has a maximum)\n"); - fprintf(ficlog, "mnbrak2 u could be left to b (if r > q parabola has a maximum)\n"); + printf("\nmnbrak2 u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q); + fprintf(ficlog,"\nmnbrak2 u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q); #endif u=(*cx)+GOLD*(*cx-*bx); fu=(*func)(u); +#ifdef DEBUG + printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx); + fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx); +#endif } /* end tests */ SHFT(*ax,*bx,*cx,u) SHFT(*fa,*fb,*fc,fu) #ifdef DEBUG - printf("mnbrak2 (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf), (*u=%.12f, fu=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu); - fprintf(ficlog, "mnbrak2 (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf), (*u=%.12f, fu=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu); + printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc); + fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc); #endif } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */ } @@ -1714,7 +1741,11 @@ int ncom; double *pcom,*xicom; double (*nrfunc)(double []); +#ifdef LINMINORIGINAL void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) +#else +void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) +#endif { double brent(double ax, double bx, double cx, double (*f)(double), double tol, double *xmin); @@ -1758,28 +1789,41 @@ void linmin(double p[], double xi[], int #ifdef LINMINORIGINAL #else if (fx != fx){ - xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */ - printf("|"); - fprintf(ficlog,"|"); + xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */ + printf("|"); + fprintf(ficlog,"|"); #ifdef DEBUGLINMIN - printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n", axs, xxs, fx,fb, fa, xx, ax, bx); + printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n", axs, xxs, fx,fb, fa, xx, ax, bx); #endif } - }while(fx != fx); + }while(fx != fx && xxs > 1.e-5); #endif #ifdef DEBUGLINMIN printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n", ax,xx,bx,fa,fx,fb); fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n", ax,xx,bx,fa,fx,fb); #endif +#ifdef LINMINORIGINAL +#else + if(fb == fx){ /* Flat function in the direction */ + xmin=xx; + *flat=1; + }else{ + *flat=0; +#endif + /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */ *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/ /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */ /* fmin = f(p[j] + xmin * xi[j]) */ /* P+lambda n in that direction (lambdamin), with TOL between abscisses */ /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */ #ifdef DEBUG - printf("retour brent fret=%.12e xmin=%.12e\n",*fret,xmin); - fprintf(ficlog,"retour brent fret=%.12e xmin=%.12e\n",*fret,xmin); + printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin); + fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin); +#endif +#ifdef LINMINORIGINAL +#else + } #endif #ifdef DEBUGLINMIN printf("linmin end "); @@ -1829,17 +1873,33 @@ such that failure to decrease by more th output, p is set to the best point found, xi is the then-current direction set, fret is the returned function value at p , and iter is the number of iterations taken. The routine linmin is used. */ +#ifdef LINMINORIGINAL +#else + int *flatdir; /* Function is vanishing in that direction */ + int flat=0; /* Function is vanishing in that direction */ +#endif void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, double (*func)(double [])) { - void linmin(double p[], double xi[], int n, double *fret, +#ifdef LINMINORIGINAL + void linmin(double p[], double xi[], int n, double *fret, double (*func)(double [])); +#else + void linmin(double p[], double xi[], int n, double *fret, + double (*func)(double []),int *flat); +#endif int i,ibig,j; double del,t,*pt,*ptt,*xit; double directest; double fp,fptt; double *xits; int niterf, itmp; +#ifdef LINMINORIGINAL +#else + + flatdir=ivector(1,n); + for (j=1;j<=n;j++) flatdir[j]=0; +#endif pt=vector(1,n); ptt=vector(1,n); @@ -1873,18 +1933,18 @@ void powell(double p[], double **xi, int rforecast_time=rcurr_time; itmp = strlen(strcurr); if(strcurr[itmp-1]=='\n') /* Windows outputs with a new line */ - strcurr[itmp-1]='\0'; + strcurr[itmp-1]='\0'; printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time); fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time); for(niterf=10;niterf<=30;niterf+=10){ - rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time); - forecast_time = *localtime(&rforecast_time); - strcpy(strfor,asctime(&forecast_time)); - itmp = strlen(strfor); - if(strfor[itmp-1]=='\n') - strfor[itmp-1]='\0'; - printf(" - if your program needs %d iterations to converge, convergence will be \n reached in %s i.e.\n on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr); - fprintf(ficlog," - if your program needs %d iterations to converge, convergence will be \n reached in %s i.e.\n on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr); + rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time); + forecast_time = *localtime(&rforecast_time); + strcpy(strfor,asctime(&forecast_time)); + itmp = strlen(strfor); + if(strfor[itmp-1]=='\n') + strfor[itmp-1]='\0'; + printf(" - if your program needs %d iterations to converge, convergence will be \n reached in %s i.e.\n on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr); + fprintf(ficlog," - if your program needs %d iterations to converge, convergence will be \n reached in %s i.e.\n on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr); } } for (i=1;i<=n;i++) { /* For each direction i */ @@ -1896,27 +1956,32 @@ void powell(double p[], double **xi, int #endif printf("%d",i);fflush(stdout); /* print direction (parameter) i */ fprintf(ficlog,"%d",i);fflush(ficlog); +#ifdef LINMINORIGINAL linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/ - /* Outputs are fret(new point p) p is updated and xit rescaled */ +#else + linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/ + flatdir[i]=flat; /* Function is vanishing in that direction i */ +#endif + /* Outputs are fret(new point p) p is updated and xit rescaled */ if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */ - /* because that direction will be replaced unless the gain del is small */ - /* in comparison with the 'probable' gain, mu^2, with the last average direction. */ - /* Unless the n directions are conjugate some gain in the determinant may be obtained */ - /* with the new direction. */ - del=fabs(fptt-(*fret)); - ibig=i; + /* because that direction will be replaced unless the gain del is small */ + /* in comparison with the 'probable' gain, mu^2, with the last average direction. */ + /* Unless the n directions are conjugate some gain in the determinant may be obtained */ + /* with the new direction. */ + del=fabs(fptt-(*fret)); + ibig=i; } #ifdef DEBUG printf("%d %.12e",i,(*fret)); fprintf(ficlog,"%d %.12e",i,(*fret)); for (j=1;j<=n;j++) { - xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5); - printf(" x(%d)=%.12e",j,xit[j]); - fprintf(ficlog," x(%d)=%.12e",j,xit[j]); + xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5); + printf(" x(%d)=%.12e",j,xit[j]); + fprintf(ficlog," x(%d)=%.12e",j,xit[j]); } for(j=1;j<=n;j++) { - printf(" p(%d)=%.12e",j,p[j]); - fprintf(ficlog," p(%d)=%.12e",j,p[j]); + printf(" p(%d)=%lf ",j,p[j]); + fprintf(ficlog," p(%d)=%lf ",j,p[j]); } printf("\n"); fprintf(ficlog,"\n"); @@ -1925,6 +1990,13 @@ void powell(double p[], double **xi, int /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit */ /* New value of last point Pn is not computed, P(n-1) */ + for(j=1;j<=n;j++) { + printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]); + fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]); + } + printf("\n"); + fprintf(ficlog,"\n"); + if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /* Did we reach enough precision? */ /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */ /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */ @@ -1933,7 +2005,7 @@ void powell(double p[], double **xi, int /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */ /* By using V1+V2+V3, the gain should be 7.82, compared with basic 1+age. */ /* By adding 10 parameters more the gain should be 18.31 */ - + /* Starting the program with initial values given by a former maximization will simply change */ /* the scales of the directions and the directions, because the are reset to canonical directions */ /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */ @@ -1961,7 +2033,10 @@ void powell(double p[], double **xi, int } #endif - +#ifdef LINMINORIGINAL +#else + free_ivector(flatdir,1,n); +#endif free_vector(xit,1,n); free_vector(xits,1,n); free_vector(ptt,1,n); @@ -1975,7 +2050,10 @@ void powell(double p[], double **xi, int pt[j]=p[j]; } fptt=(*func)(ptt); /* f_3 */ -#ifdef POWELLF1F3 +#ifdef NODIRECTIONCHANGEDUNTILNITER /* No change in drections until some iterations are done */ + if (*iter <=4) { +#else +#ifdef POWELLNOF3INFF1TEST /* skips test F3 0 */ + /* mu² and del² are equal when f3=f1 */ + /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */ + /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */ + /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0 */ + /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0 */ #ifdef NRCORIGINAL t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/ #else @@ -2007,57 +2093,76 @@ void powell(double p[], double **xi, int if (t < 0.0) { /* Then we use it for new direction */ #else if (directest*t < 0.0) { /* Contradiction between both tests */ - printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del); + printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del); printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt); - fprintf(ficlog,"directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del); + fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del); fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt); } if (directest < 0.0) { /* Then we use it for new direction */ #endif #ifdef DEBUGLINMIN - printf("Before linmin in direction P%d-P0\n",n); - for (j=1;j<=n;j++) { - printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]); - fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]); - if(j % ncovmodel == 0){ - printf("\n"); - fprintf(ficlog,"\n"); - } - } + printf("Before linmin in direction P%d-P0\n",n); + for (j=1;j<=n;j++) { + printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]); + fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]); + if(j % ncovmodel == 0){ + printf("\n"); + fprintf(ficlog,"\n"); + } + } #endif - linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/ -#ifdef DEBUGLINMIN - for (j=1;j<=n;j++) { - printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]); - fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]); - if(j % ncovmodel == 0){ - printf("\n"); - fprintf(ficlog,"\n"); - } - } +#ifdef LINMINORIGINAL + linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/ +#else + linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/ + flatdir[i]=flat; /* Function is vanishing in that direction i */ #endif - for (j=1;j<=n;j++) { - xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */ - xi[j][n]=xit[j]; /* and this nth direction by the by the average p_0 p_n */ - } - printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig); - fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig); +#ifdef DEBUGLINMIN + for (j=1;j<=n;j++) { + printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]); + fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]); + if(j % ncovmodel == 0){ + printf("\n"); + fprintf(ficlog,"\n"); + } + } +#endif + for (j=1;j<=n;j++) { + xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */ + xi[j][n]=xit[j]; /* and this nth direction by the by the average p_0 p_n */ + } +#ifdef LINMINORIGINAL +#else + printf("Flat directions\n"); + fprintf(ficlog,"Flat directions\n"); + for (j=1;j<=n;j++) { + printf("flatdir[%d]=%d ",j,flatdir[j]); + fprintf(ficlog,"flatdir[%d]=%d ",j,flatdir[j]); + } + printf("\n"); + fprintf(ficlog,"\n"); +#endif + printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig); + fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig); + #ifdef DEBUG - printf("Direction changed last moved %d in place of ibig=%d, new last is the average:\n",n,ibig); - fprintf(ficlog,"Direction changed last moved %d in place of ibig=%d, new last is the average:\n",n,ibig); - for(j=1;j<=n;j++){ - printf(" %.12e",xit[j]); - fprintf(ficlog," %.12e",xit[j]); - } - printf("\n"); - fprintf(ficlog,"\n"); + printf("Direction changed last moved %d in place of ibig=%d, new last is the average:\n",n,ibig); + fprintf(ficlog,"Direction changed last moved %d in place of ibig=%d, new last is the average:\n",n,ibig); + for(j=1;j<=n;j++){ + printf(" %lf",xit[j]); + fprintf(ficlog," %lf",xit[j]); + } + printf("\n"); + fprintf(ficlog,"\n"); #endif } /* end of t or directest negative */ -#ifdef POWELLF1F3 +#ifdef POWELLNOF3INFF1TEST #else } /* end if (fptt < fp) */ #endif + } /*NODIRECTIONCHANGEDUNTILNITER No change in drections until some iterations are done */ +#endif } /* loop iteration */ } @@ -2331,65 +2436,65 @@ double **pmij(double **ps, double *cov, /*double t34;*/ int i,j, nc, ii, jj; - for(i=1; i<= nlstate; i++){ - for(j=1; ji s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */ - } - ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */ - } - } + for(i=1; i<= nlstate; i++){ + for(j=1; ji s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */ + } + ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */ + } + } - for(i=1; i<= nlstate; i++){ - s1=0; - for(j=1; ji} pij/pii=(1-pii)/pii and thus pii is known from s1 */ - ps[i][i]=1./(s1+1.); - /* Computing other pijs */ - for(j=1; ji} pij/pii=(1-pii)/pii and thus pii is known from s1 */ + ps[i][i]=1./(s1+1.); + /* Computing other pijs */ + for(j=1; j= 1.e-10){ - /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */ - /* doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */ - /* }else if(agefin >= agemaxpar+stepm/YEARM){ */ - /* doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */ - /* }else */ - doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); - }else{ - printf("ii=%d, i=%d, doldm=%lf dsavm=%lf, probs=%lf, sumnew=%lf,agefin=%d\n",ii,j,doldm[ii][j],dsavm[ii][j],prevacurrent[(int)agefin][ii][ij],sumnew, (int)agefin); - } - } /*End ii */ - } /* End j, At the end doldm is diag[1/(w_1p1i+w_2 p2i)] */ - /* left Product of this diag matrix by dsavm=Px (newm=dsavm*doldm) */ - bbmij=matprod2(dnewm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, doldm); /* Bug Valgrind */ - /* dsavm=doldm; /\* dsavm is now diag [1/(w_1p1i+w_2 p2i)] but can be overwritten*\/ */ - /* doldm=dnewm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */ - /* dnewm=dsavm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */ - /* left Product of this matrix by diag matrix of prevalences (savm) */ - for (j=1;j<=nlstate+ndeath;j++){ - for (ii=1;ii<=nlstate+ndeath;ii++){ - dsavm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij] : 0.0); - } - } /* End j, At the end oldm is diag[1/(w_1p1i+w_2 p2i)] */ - ps=matprod2(doldm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dnewm); /* Bug Valgrind */ - /* newm or out is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */ - /* end bmij */ - return ps; + dnewm=ddnewms; + dsavm=ddsavms; + + agefin=cov[2]; + /* bmij *//* age is cov[2], ij is included in cov, but we need for + the observed prevalence (with this covariate ij) */ + dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); + /* We do have the matrix Px in savm and we need pij */ + for (j=1;j<=nlstate+ndeath;j++){ + sumnew=0.; /* w1 p11 + w2 p21 only on live states */ + for (ii=1;ii<=nlstate;ii++){ + sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; + } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */ + for (ii=1;ii<=nlstate+ndeath;ii++){ + if(sumnew >= 1.e-10){ + /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */ + /* doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */ + /* }else if(agefin >= agemaxpar+stepm/YEARM){ */ + /* doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */ + /* }else */ + doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); + }else{ + printf("ii=%d, i=%d, doldm=%lf dsavm=%lf, probs=%lf, sumnew=%lf,agefin=%d\n",ii,j,doldm[ii][j],dsavm[ii][j],prevacurrent[(int)agefin][ii][ij],sumnew, (int)agefin); + } + } /*End ii */ + } /* End j, At the end doldm is diag[1/(w_1p1i+w_2 p2i)] */ + /* left Product of this diag matrix by dsavm=Px (newm=dsavm*doldm) */ + bbmij=matprod2(dnewm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, doldm); /* Bug Valgrind */ + /* dsavm=doldm; /\* dsavm is now diag [1/(w_1p1i+w_2 p2i)] but can be overwritten*\/ */ + /* doldm=dnewm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */ + /* dnewm=dsavm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */ + /* left Product of this matrix by diag matrix of prevalences (savm) */ + for (j=1;j<=nlstate+ndeath;j++){ + for (ii=1;ii<=nlstate+ndeath;ii++){ + dsavm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij] : 0.0); + } + } /* End j, At the end oldm is diag[1/(w_1p1i+w_2 p2i)] */ + ps=matprod2(doldm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dnewm); /* Bug Valgrind */ + /* newm or out is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */ + /* end bmij */ + return ps; } /*************** transition probabilities ***************/ @@ -2657,7 +2762,7 @@ double ***hpxij(double ***po, int nhstep /************* Higher Back Matrix Product ***************/ /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */ - double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij ) +double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij ) { /* Computes the transition matrix starting at age 'age' over 'nhstepm*hstepm*stepm' months (i.e. until @@ -2669,16 +2774,16 @@ double ***hpxij(double ***po, int nhstep Model is determined by parameters x and covariates have to be included manually here. - */ + */ int i, j, d, h, k; double **out, cov[NCOVMAX+1]; double **newm; double agexact; double agebegin, ageend; - double **oldm, **savm; + double **oldm, **savm; - oldm=oldms;savm=savms; + oldm=oldms;savm=savms; /* Hstepm could be zero and should return the unit matrix */ for (i=1;i<=nlstate+ndeath;i++) for (j=1;j<=nlstate+ndeath;j++){ @@ -2695,27 +2800,27 @@ double ***hpxij(double ***po, int nhstep /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */ cov[2]=agexact; if(nagesqr==1) - cov[3]= agexact*agexact; + cov[3]= agexact*agexact; for (k=1; k<=cptcovn;k++) - cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; - /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */ + cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; + /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */ for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */ - /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */ - cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; - /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */ + /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */ + cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; + /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */ for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */ - cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; - /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */ + cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; + /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */ /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/ /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/ /* Careful transposed matrix */ - /* age is in cov[2] */ + /* age is in cov[2] */ /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */ - /* 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */ + /* 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */ out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\ - 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); + 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* if((int)age == 70){ */ /* printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */ /* for(i=1; i<=nlstate+ndeath; i++) { */ @@ -2735,12 +2840,12 @@ double ***hpxij(double ***po, int nhstep } for(i=1; i<=nlstate+ndeath; i++) for(j=1;j<=nlstate+ndeath;j++) { - po[i][j][h]=newm[i][j]; - /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/ + po[i][j][h]=newm[i][j]; + /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/ } /*printf("h=%d ",h);*/ } /* end h */ - /* printf("\n H=%d \n",h); */ + /* printf("\n H=%d \n",h); */ return po; } @@ -2768,118 +2873,142 @@ double ***hpxij(double ***po, int nhstep /*************** log-likelihood *************/ double func( double *x) { - int i, ii, j, k, mi, d, kk; - double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1]; - double **out; - double sw; /* Sum of weights */ - double lli; /* Individual log likelihood */ - int s1, s2; - double bbh, survp; - long ipmx; - double agexact; - /*extern weight */ - /* We are differentiating ll according to initial status */ - /* for (i=1;i<=npar;i++) printf("%f ", x[i]);*/ - /*for(i=1;i 1 the results are less biased than in previous versions. - */ - s1=s[mw[mi][i]][i]; - s2=s[mw[mi+1][i]][i]; - bbh=(double)bh[mi][i]/(double)stepm; - /* bias bh is positive if real duration - * is higher than the multiple of stepm and negative otherwise. - */ - /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/ - if( s2 > nlstate){ - /* i.e. if s2 is a death state and if the date of death is known - then the contribution to the likelihood is the probability to - die between last step unit time and current step unit time, - which is also equal to probability to die before dh - minus probability to die before dh-stepm . - In version up to 0.92 likelihood was computed - as if date of death was unknown. Death was treated as any other - health state: the date of the interview describes the actual state - and not the date of a change in health state. The former idea was - to consider that at each interview the state was recorded - (healthy, disable or death) and IMaCh was corrected; but when we - introduced the exact date of death then we should have modified - the contribution of an exact death to the likelihood. This new - contribution is smaller and very dependent of the step unit - stepm. It is no more the probability to die between last interview - and month of death but the probability to survive from last - interview up to one month before death multiplied by the - probability to die within a month. Thanks to Chris - Jackson for correcting this bug. Former versions increased - mortality artificially. The bad side is that we add another loop - which slows down the processing. The difference can be up to 10% - lower mortality. - */ - /* If, at the beginning of the maximization mostly, the - cumulative probability or probability to be dead is - constant (ie = 1) over time d, the difference is equal to - 0. out[s1][3] = savm[s1][3]: probability, being at state - s1 at precedent wave, to be dead a month before current - wave is equal to probability, being at state s1 at - precedent wave, to be dead at mont of the current - wave. Then the observed probability (that this person died) - is null according to current estimated parameter. In fact, - it should be very low but not zero otherwise the log go to - infinity. - */ + /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] + is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] + has been calculated etc */ + /* For an individual i, wav[i] gives the number of effective waves */ + /* We compute the contribution to Likelihood of each effective transition + mw[mi][i] is real wave of the mi th effectve wave */ + /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i]; + s2=s[mw[mi+1][i]][i]; + And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i] + But if the variable is not in the model TTvar[iv] is the real variable effective in the model: + meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i] + */ + for(mi=1; mi<= wav[i]-1; mi++){ + for(itv=1; itv <= ntveff; itv++){ /* Varying dummy covariates */ + cov[ioffset+itv]=cotvar[mw[mi][i]][itv][i]; + } + for(iqtv=1; iqtv <= nqtveff; iqtv++){ /* Varying quantitatives covariates */ + cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][iqtv][i]; + } + /* ioffset=2+nagesqr+cptcovn+nqv+ntv+nqtv; */ + for (ii=1;ii<=nlstate+ndeath;ii++) + for (j=1;j<=nlstate+ndeath;j++){ + oldm[ii][j]=(ii==j ? 1.0 : 0.0); + savm[ii][j]=(ii==j ? 1.0 : 0.0); + } + for(d=0; d 1 the results are less biased than in previous versions. + */ + s1=s[mw[mi][i]][i]; + s2=s[mw[mi+1][i]][i]; + bbh=(double)bh[mi][i]/(double)stepm; + /* bias bh is positive if real duration + * is higher than the multiple of stepm and negative otherwise. + */ + /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/ + if( s2 > nlstate){ + /* i.e. if s2 is a death state and if the date of death is known + then the contribution to the likelihood is the probability to + die between last step unit time and current step unit time, + which is also equal to probability to die before dh + minus probability to die before dh-stepm . + In version up to 0.92 likelihood was computed + as if date of death was unknown. Death was treated as any other + health state: the date of the interview describes the actual state + and not the date of a change in health state. The former idea was + to consider that at each interview the state was recorded + (healthy, disable or death) and IMaCh was corrected; but when we + introduced the exact date of death then we should have modified + the contribution of an exact death to the likelihood. This new + contribution is smaller and very dependent of the step unit + stepm. It is no more the probability to die between last interview + and month of death but the probability to survive from last + interview up to one month before death multiplied by the + probability to die within a month. Thanks to Chris + Jackson for correcting this bug. Former versions increased + mortality artificially. The bad side is that we add another loop + which slows down the processing. The difference can be up to 10% + lower mortality. + */ + /* If, at the beginning of the maximization mostly, the + cumulative probability or probability to be dead is + constant (ie = 1) over time d, the difference is equal to + 0. out[s1][3] = savm[s1][3]: probability, being at state + s1 at precedent wave, to be dead a month before current + wave is equal to probability, being at state s1 at + precedent wave, to be dead at mont of the current + wave. Then the observed probability (that this person died) + is null according to current estimated parameter. In fact, + it should be very low but not zero otherwise the log go to + infinity. + */ /* #ifdef INFINITYORIGINAL */ /* lli=log(out[s1][s2] - savm[s1][s2]); */ /* #else */ @@ -2888,187 +3017,187 @@ double func( double *x) /* else */ /* lli=log(out[s1][s2] - savm[s1][s2]); */ /* #endif */ - lli=log(out[s1][s2] - savm[s1][s2]); + lli=log(out[s1][s2] - savm[s1][s2]); - } else if ( s2==-1 ) { /* alive */ - for (j=1,survp=0. ; j<=nlstate; j++) - survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j]; - /*survp += out[s1][j]; */ - lli= log(survp); - } - else if (s2==-4) { - for (j=3,survp=0. ; j<=nlstate; j++) - survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j]; - lli= log(survp); - } - else if (s2==-5) { - for (j=1,survp=0. ; j<=2; j++) - survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j]; - lli= log(survp); - } - else{ - lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */ - /* lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */ - } - /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/ - /*if(lli ==000.0)*/ - /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */ - ipmx +=1; - sw += weight[i]; - ll[s[mw[mi][i]][i]] += 2*weight[i]*lli; - /* if (lli < log(mytinydouble)){ */ - /* printf("Close to inf lli = %.10lf < %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */ - /* fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */ - /* } */ - } /* end of wave */ - } /* end of individual */ - } else if(mle==2){ - for (i=1,ipmx=0, sw=0.; i<=imx; i++){ - for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; - for(mi=1; mi<= wav[i]-1; mi++){ - for (ii=1;ii<=nlstate+ndeath;ii++) - for (j=1;j<=nlstate+ndeath;j++){ - oldm[ii][j]=(ii==j ? 1.0 : 0.0); - savm[ii][j]=(ii==j ? 1.0 : 0.0); - } - for(d=0; d<=dh[mi][i]; d++){ - newm=savm; - agexact=agev[mw[mi][i]][i]+d*stepm/YEARM; - cov[2]=agexact; - if(nagesqr==1) - cov[3]= agexact*agexact; - for (kk=1; kk<=cptcovage;kk++) { - cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; - } - out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, - 1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); - savm=oldm; - oldm=newm; - } /* end mult */ - - s1=s[mw[mi][i]][i]; - s2=s[mw[mi+1][i]][i]; - bbh=(double)bh[mi][i]/(double)stepm; - lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */ - ipmx +=1; - sw += weight[i]; - ll[s[mw[mi][i]][i]] += 2*weight[i]*lli; - } /* end of wave */ - } /* end of individual */ - } else if(mle==3){ /* exponential inter-extrapolation */ - for (i=1,ipmx=0, sw=0.; i<=imx; i++){ - for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; - for(mi=1; mi<= wav[i]-1; mi++){ - for (ii=1;ii<=nlstate+ndeath;ii++) - for (j=1;j<=nlstate+ndeath;j++){ - oldm[ii][j]=(ii==j ? 1.0 : 0.0); - savm[ii][j]=(ii==j ? 1.0 : 0.0); - } - for(d=0; d1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */ - ipmx +=1; - sw += weight[i]; - ll[s[mw[mi][i]][i]] += 2*weight[i]*lli; - } /* end of wave */ - } /* end of individual */ - }else if (mle==4){ /* ml=4 no inter-extrapolation */ - for (i=1,ipmx=0, sw=0.; i<=imx; i++){ - for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; - for(mi=1; mi<= wav[i]-1; mi++){ - for (ii=1;ii<=nlstate+ndeath;ii++) - for (j=1;j<=nlstate+ndeath;j++){ - oldm[ii][j]=(ii==j ? 1.0 : 0.0); - savm[ii][j]=(ii==j ? 1.0 : 0.0); - } - for(d=0; d(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */ + } + /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/ + /*if(lli ==000.0)*/ + /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */ + ipmx +=1; + sw += weight[i]; + ll[s[mw[mi][i]][i]] += 2*weight[i]*lli; + /* if (lli < log(mytinydouble)){ */ + /* printf("Close to inf lli = %.10lf < %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */ + /* fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */ + /* } */ + } /* end of wave */ + } /* end of individual */ + } else if(mle==2){ + for (i=1,ipmx=0, sw=0.; i<=imx; i++){ + for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; + for(mi=1; mi<= wav[i]-1; mi++){ + for (ii=1;ii<=nlstate+ndeath;ii++) + for (j=1;j<=nlstate+ndeath;j++){ + oldm[ii][j]=(ii==j ? 1.0 : 0.0); + savm[ii][j]=(ii==j ? 1.0 : 0.0); + } + for(d=0; d<=dh[mi][i]; d++){ + newm=savm; + agexact=agev[mw[mi][i]][i]+d*stepm/YEARM; + cov[2]=agexact; + if(nagesqr==1) + cov[3]= agexact*agexact; + for (kk=1; kk<=cptcovage;kk++) { + cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; + } + out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, + 1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); + savm=oldm; + oldm=newm; + } /* end mult */ + + s1=s[mw[mi][i]][i]; + s2=s[mw[mi+1][i]][i]; + bbh=(double)bh[mi][i]/(double)stepm; + lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */ + ipmx +=1; + sw += weight[i]; + ll[s[mw[mi][i]][i]] += 2*weight[i]*lli; + } /* end of wave */ + } /* end of individual */ + } else if(mle==3){ /* exponential inter-extrapolation */ + for (i=1,ipmx=0, sw=0.; i<=imx; i++){ + for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; + for(mi=1; mi<= wav[i]-1; mi++){ + for (ii=1;ii<=nlstate+ndeath;ii++) + for (j=1;j<=nlstate+ndeath;j++){ + oldm[ii][j]=(ii==j ? 1.0 : 0.0); + savm[ii][j]=(ii==j ? 1.0 : 0.0); + } + for(d=0; d1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */ + ipmx +=1; + sw += weight[i]; + ll[s[mw[mi][i]][i]] += 2*weight[i]*lli; + } /* end of wave */ + } /* end of individual */ + }else if (mle==4){ /* ml=4 no inter-extrapolation */ + for (i=1,ipmx=0, sw=0.; i<=imx; i++){ + for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; + for(mi=1; mi<= wav[i]-1; mi++){ + for (ii=1;ii<=nlstate+ndeath;ii++) + for (j=1;j<=nlstate+ndeath;j++){ + oldm[ii][j]=(ii==j ? 1.0 : 0.0); + savm[ii][j]=(ii==j ? 1.0 : 0.0); + } + for(d=0; d nlstate){ - lli=log(out[s1][s2] - savm[s1][s2]); - } else if ( s2==-1 ) { /* alive */ - for (j=1,survp=0. ; j<=nlstate; j++) - survp += out[s1][j]; - lli= log(survp); - }else{ - lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */ - } - ipmx +=1; - sw += weight[i]; - ll[s[mw[mi][i]][i]] += 2*weight[i]*lli; + out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, + 1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); + savm=oldm; + oldm=newm; + } /* end mult */ + + s1=s[mw[mi][i]][i]; + s2=s[mw[mi+1][i]][i]; + if( s2 > nlstate){ + lli=log(out[s1][s2] - savm[s1][s2]); + } else if ( s2==-1 ) { /* alive */ + for (j=1,survp=0. ; j<=nlstate; j++) + survp += out[s1][j]; + lli= log(survp); + }else{ + lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */ + } + ipmx +=1; + sw += weight[i]; + ll[s[mw[mi][i]][i]] += 2*weight[i]*lli; /* printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */ - } /* end of wave */ - } /* end of individual */ - }else{ /* ml=5 no inter-extrapolation no jackson =0.8a */ - for (i=1,ipmx=0, sw=0.; i<=imx; i++){ - for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; - for(mi=1; mi<= wav[i]-1; mi++){ - for (ii=1;ii<=nlstate+ndeath;ii++) - for (j=1;j<=nlstate+ndeath;j++){ - oldm[ii][j]=(ii==j ? 1.0 : 0.0); - savm[ii][j]=(ii==j ? 1.0 : 0.0); - } - for(d=0; d nlstate && (mle <5) ){ /* Jackson */ - lli=log(out[s1][s2] - savm[s1][s2]); + lli=log(out[s1][s2] - savm[s1][s2]); } else if ( s2==-1 ) { /* alive */ - for (j=1,survp=0. ; j<=nlstate; j++) - survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j]; - lli= log(survp); + for (j=1,survp=0. ; j<=nlstate; j++) + survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j]; + lli= log(survp); }else if (mle==1){ - lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */ + lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */ } else if(mle==2){ - lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */ + lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */ } else if(mle==3){ /* exponential inter-extrapolation */ - lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */ + lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */ } else if (mle==4){ /* mle=4 no inter-extrapolation */ - lli=log(out[s1][s2]); /* Original formula */ + lli=log(out[s1][s2]); /* Original formula */ } else{ /* mle=0 back to 1 */ - lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */ - /*lli=log(out[s1][s2]); */ /* Original formula */ + lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */ + /*lli=log(out[s1][s2]); */ /* Original formula */ } /* End of if */ ipmx +=1; sw += weight[i]; ll[s[mw[mi][i]][i]] += 2*weight[i]*lli; /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */ if(globpr){ - fprintf(ficresilk,"%9ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %11.6f %8.4f %8.3f\ + fprintf(ficresilk,"%9ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\ %11.6f %11.6f %11.6f ", \ - num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw, - 2*weight[i]*lli,out[s1][s2],savm[s1][s2]); - for(k=1,llt=0.,l=0.; k<=nlstate; k++){ - llt +=ll[k]*gipmx/gsw; - fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw); - } - fprintf(ficresilk," %10.6f\n", -llt); + num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw, + 2*weight[i]*lli,out[s1][s2],savm[s1][s2]); + for(k=1,llt=0.,l=0.; k<=nlstate; k++){ + llt +=ll[k]*gipmx/gsw; + fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw); + } + fprintf(ficresilk," %10.6f\n", -llt); } } /* end of wave */ } /* end of individual */ @@ -3684,6 +3829,8 @@ void pstamp(FILE *fichier) int mi; /* Effective wave */ int first; double ***freq; /* Frequencies */ + double *meanq; + double **meanqt; double *pp, **prop, *posprop, *pospropt; double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0; char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH]; @@ -3694,6 +3841,8 @@ void pstamp(FILE *fichier) posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ /* prop=matrix(1,nlstate,iagemin,iagemax+3); */ + meanq=vector(1,nqveff); + meanqt=matrix(1,lastpass,1,nqtveff); strcpy(fileresp,"P_"); strcat(fileresp,fileresu); /*strcat(fileresphtm,fileresu);*/ @@ -3736,7 +3885,7 @@ Title=%s
Datafile=%s Firstpass=%d La freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+3+AGEMARGE); j1=0; - j=cptcoveff; + j=ncoveff; if (cptcovn<1) {j=1;ncodemax[1]=1;} first=1; @@ -3748,7 +3897,7 @@ Title=%s
Datafile=%s Firstpass=%d La Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff */ - for (j1 = 1; j1 <= (int) pow(2,cptcoveff); j1++){ /* Loop on covariates combination */ + for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on covariates combination excluding varying and quantitatives */ posproptt=0.; /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]); scanf("%d", i);*/ @@ -3763,16 +3912,30 @@ Title=%s
Datafile=%s Firstpass=%d La posprop[i]=0; pospropt[i]=0; } + for (z1=1; z1<= nqveff; z1++) { + meanq[z1]+=0.; + for(m=1;m<=lastpass;m++){ + meanqt[m][z1]=0.; + } + } dateintsum=0; k2cpt=0; - + /* For that comination of covariate j1, we count and print the frequencies */ for (iind=1; iind<=imx; iind++) { /* For each individual iind */ bool=1; - if (cptcovn>0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */ - for (z1=1; z1<=cptcoveff; z1++) { + if (nqveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */ + for (z1=1; z1<= nqveff; z1++) { + meanq[z1]+=coqvar[Tvar[z1]][iind]; + } + for (z1=1; z1<=ncoveff; z1++) { + /* if(Tvaraff[z1] ==-20){ */ + /* /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */ + /* }else if(Tvaraff[z1] ==-10){ */ + /* /\* sumnew+=coqvar[z1][iind]; *\/ */ + /* }else */ if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ - /* Tests if the value of each of the covariates of i is equal to filter j1 */ + /* Tests if this individual i responded to j1 (V4=1 V3=0) */ bool=0; /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1), @@ -3782,7 +3945,7 @@ Title=%s
Datafile=%s Firstpass=%d La } /* end z1 */ } /* cptcovn > 0 */ - if (bool==1){ + if (bool==1){ /* We selected an individual iin satisfying combination j1 */ /* for(m=firstpass; m<=lastpass; m++){ */ for(mi=1; miDatafile=%s Firstpass=%d La /* fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/ pstamp(ficresp); - if (cptcovn>0) { + if (ncoveff>0) { fprintf(ficresp, "\n#********** Variable "); fprintf(ficresphtm, "\n

********** Variable "); fprintf(ficresphtmfr, "\n

********** Variable "); - for (z1=1; z1<=cptcoveff; z1++){ + for (z1=1; z1<=ncoveff; z1++){ fprintf(ficresp, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]); fprintf(ficresphtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]); fprintf(ficresphtmfr, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]); @@ -3835,7 +3998,7 @@ Title=%s
Datafile=%s Firstpass=%d La fprintf(ficresphtm, "**********

\n"); fprintf(ficresphtmfr, "**********\n"); fprintf(ficlog, "\n#********** Variable "); - for (z1=1; z1<=cptcoveff; z1++) fprintf(ficlog, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]); + for (z1=1; z1<=ncoveff; z1++) fprintf(ficlog, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]); fprintf(ficlog, "**********\n"); } fprintf(ficresphtm,""); @@ -3962,9 +4125,9 @@ Title=%s
Datafile=%s Firstpass=%d La fprintf(ficresphtm,""); for(jk=1; jk <=nlstate ; jk++){ if(posproptt < 1.e-5){ - fprintf(ficresphtm,"",pospropt[jk]/posproptt,pospropt[jk],posproptt); + fprintf(ficresphtm,"",pospropt[jk],posproptt); }else{ - fprintf(ficresphtm,"",pospropt[jk]/posproptt,pospropt[jk],posproptt); + fprintf(ficresphtm,"",pospropt[jk]/posproptt,pospropt[jk],posproptt); } } fprintf(ficresphtm,"\n"); @@ -3986,106 +4149,108 @@ Title=%s
Datafile=%s Firstpass=%d La fclose(ficresp); fclose(ficresphtm); fclose(ficresphtmfr); + free_vector(meanq,1,nqveff); + free_matrix(meanqt,1,lastpass,1,nqtveff); free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+3+AGEMARGE); free_vector(pospropt,1,nlstate); free_vector(posprop,1,nlstate); free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+3+AGEMARGE); free_vector(pp,1,nlstate); - /* End of Freq */ + /* End of freqsummary */ } /************ Prevalence ********************/ -void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass) -{ - /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people - in each health status at the date of interview (if between dateprev1 and dateprev2). - We still use firstpass and lastpass as another selection. - */ + void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass) + { + /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people + in each health status at the date of interview (if between dateprev1 and dateprev2). + We still use firstpass and lastpass as another selection. + */ - int i, m, jk, j1, bool, z1,j; - int mi; /* Effective wave */ - int iage; - double agebegin, ageend; - - double **prop; - double posprop; - double y2; /* in fractional years */ - int iagemin, iagemax; - int first; /** to stop verbosity which is redirected to log file */ - - iagemin= (int) agemin; - iagemax= (int) agemax; - /*pp=vector(1,nlstate);*/ - prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+3+AGEMARGE); - /* freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/ - j1=0; - - /*j=cptcoveff;*/ - if (cptcovn<1) {j=1;ncodemax[1]=1;} - - first=1; - for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */ - for (i=1; i<=nlstate; i++) - for(iage=iagemin-AGEMARGE; iage <= iagemax+3+AGEMARGE; iage++) - prop[i][iage]=0.0; - - for (i=1; i<=imx; i++) { /* Each individual */ - bool=1; - if (cptcovn>0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */ - for (z1=1; z1<=cptcoveff; z1++) /* For each covariate, look at the value for individual i and checks if it is equal to the corresponding value of this covariate according to current combination j1*/ - if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) - bool=0; - } - if (bool==1) { /* For this combination of covariates values, this individual fits */ - /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */ - for(mi=1; mi=firstpass && m <=lastpass){ - y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */ - if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */ - if(agev[m][i]==0) agev[m][i]=iagemax+1; - if(agev[m][i]==1) agev[m][i]=iagemax+2; - if((int)agev[m][i] iagemax+3+AGEMARGE){ - printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); - exit(1); - } - if (s[m][i]>0 && s[m][i]<=nlstate) { - /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/ - prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */ - prop[s[m][i]][iagemax+3] += weight[i]; - } /* end valid statuses */ - } /* end selection of dates */ - } /* end selection of waves */ - } /* end effective waves */ - } /* end bool */ - } - for(i=iagemin; i <= iagemax+3; i++){ - for(jk=1,posprop=0; jk <=nlstate ; jk++) { - posprop += prop[jk][i]; - } - - for(jk=1; jk <=nlstate ; jk++){ - if( i <= iagemax){ - if(posprop>=1.e-5){ - probs[i][jk][j1]= prop[jk][i]/posprop; - } else{ - if(first==1){ - first=0; - printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others on log file...\n",jk,i,j1,probs[i][jk][j1]); - } - } - } - }/* end jk */ - }/* end i */ - /*} *//* end i1 */ - } /* end j1 */ - - /* free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/ - /*free_vector(pp,1,nlstate);*/ - free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+3+AGEMARGE); -} /* End of prevalence */ + int i, m, jk, j1, bool, z1,j; + int mi; /* Effective wave */ + int iage; + double agebegin, ageend; + + double **prop; + double posprop; + double y2; /* in fractional years */ + int iagemin, iagemax; + int first; /** to stop verbosity which is redirected to log file */ + + iagemin= (int) agemin; + iagemax= (int) agemax; + /*pp=vector(1,nlstate);*/ + prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+3+AGEMARGE); + /* freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/ + j1=0; + + /*j=cptcoveff;*/ + if (cptcovn<1) {j=1;ncodemax[1]=1;} + + first=1; + for(j1=1; j1<= (int) pow(2,nqveff);j1++){ /* For each combination of covariate */ + for (i=1; i<=nlstate; i++) + for(iage=iagemin-AGEMARGE; iage <= iagemax+3+AGEMARGE; iage++) + prop[i][iage]=0.0; + + for (i=1; i<=imx; i++) { /* Each individual */ + bool=1; + if (cptcovn>0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */ + for (z1=1; z1<=nqveff; z1++) /* For each covariate, look at the value for individual i and checks if it is equal to the corresponding value of this covariate according to current combination j1*/ + if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) + bool=0; + } + if (bool==1) { /* For this combination of covariates values, this individual fits */ + /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */ + for(mi=1; mi=firstpass && m <=lastpass){ + y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */ + if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */ + if(agev[m][i]==0) agev[m][i]=iagemax+1; + if(agev[m][i]==1) agev[m][i]=iagemax+2; + if((int)agev[m][i] iagemax+3+AGEMARGE){ + printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); + exit(1); + } + if (s[m][i]>0 && s[m][i]<=nlstate) { + /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/ + prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */ + prop[s[m][i]][iagemax+3] += weight[i]; + } /* end valid statuses */ + } /* end selection of dates */ + } /* end selection of waves */ + } /* end effective waves */ + } /* end bool */ + } + for(i=iagemin; i <= iagemax+3; i++){ + for(jk=1,posprop=0; jk <=nlstate ; jk++) { + posprop += prop[jk][i]; + } + + for(jk=1; jk <=nlstate ; jk++){ + if( i <= iagemax){ + if(posprop>=1.e-5){ + probs[i][jk][j1]= prop[jk][i]/posprop; + } else{ + if(first==1){ + first=0; + printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others on log file...\n",jk,i,j1,probs[i][jk][j1]); + } + } + } + }/* end jk */ + }/* end i */ + /*} *//* end i1 */ + } /* end j1 */ + + /* free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/ + /*free_vector(pp,1,nlstate);*/ + free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+3+AGEMARGE); + } /* End of prevalence */ /************* Waves Concatenation ***************/ @@ -4098,10 +4263,10 @@ void concatwav(int wav[], int **dh, int and mw[mi+1][i]. dh depends on stepm. */ - int i, mi, m; + int i=0, mi=0, m=0, mli=0; /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1; double sum=0., jmean=0.;*/ - int first, firstwo, firsthree, firstfour; + int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0; int j, k=0,jk, ju, jl; double sum=0.; first=0; @@ -4111,160 +4276,190 @@ void concatwav(int wav[], int **dh, int jmin=100000; jmax=-1; jmean=0.; + +/* Treating live states */ for(i=1; i<=imx; i++){ /* For simple cases and if state is death */ - mi=0; + mi=0; /* First valid wave */ + mli=0; /* Last valid wave */ m=firstpass; while(s[m][i] <= nlstate){ /* a live state */ - if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */ - mw[++mi][i]=m; + if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */ + mli=m-1;/* mw[++mi][i]=m-1; */ + }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */ + mw[++mi][i]=m; + mli=m; + } /* else might be a useless wave -1 and mi is not incremented and mw[mi] not updated */ + if(m < lastpass){ /* m < lastpass, standard case */ + m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */ } - if(m >=lastpass){ - if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){ - if(firsthree == 0){ - printf("Information! Unknown health status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m); - firsthree=1; - } - fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m); - mw[++mi][i]=m; - } - if(s[m][i]==-2){ /* Vital status is really unknown */ - nbwarn++; - if((int)anint[m][i] == 9999){ /* Has the vital status really been verified? */ - printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m); - fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m); - } - break; - } - break; - } - else - m++; + else{ /* m >= lastpass, eventual special issue with warning */ +#ifdef UNKNOWNSTATUSNOTCONTRIBUTING + break; +#else + if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){ + if(firsthree == 0){ + printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m); + firsthree=1; + } + fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m); + mw[++mi][i]=m; + mli=m; + } + if(s[m][i]==-2){ /* Vital status is really unknown */ + nbwarn++; + if((int)anint[m][i] == 9999){ /* Has the vital status really been verified? */ + printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m); + fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m); + } + break; + } + break; +#endif + }/* End m >= lastpass */ }/* end while */ - + + /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */ /* After last pass */ +/* Treating death states */ if (s[m][i] > nlstate){ /* In a death state */ + /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */ + /* } */ mi++; /* Death is another wave */ /* if(mi==0) never been interviewed correctly before death */ - /* Only death is a correct wave */ + /* Only death is a correct wave */ mw[mi][i]=m; - }else if ((int) andc[i] != 9999) { /* Status is either death or negative. A death occured after lastpass, we can't take it into account because of potential bias */ + } +#ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE + else if ((int) andc[i] != 9999) { /* Status is negative. A death occured after lastpass, we can't take it into account because of potential bias */ /* m++; */ /* mi++; */ /* s[m][i]=nlstate+1; /\* We are setting the status to the last of non live state *\/ */ /* mw[mi][i]=m; */ - nberr++; if ((int)anint[m][i]!= 9999) { /* date of last interview is known */ - if(firstwo==0){ - printf("Error! Death for individual %ld line=%d occurred %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m ); - firstwo=1; - } - fprintf(ficlog,"Error! Death for individual %ld line=%d occurred %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m ); + if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */ + nbwarn++; + if(firstfiv==0){ + printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m ); + firstfiv=1; + }else{ + fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m ); + } + }else{ /* Death occured afer last wave potential bias */ + nberr++; + if(firstwo==0){ + printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m ); + firstwo=1; + } + fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m ); + } }else{ /* end date of interview is known */ - /* death is known but not confirmed by death status at any wave */ - if(firstfour==0){ - printf("Error! Death for individual %ld line=%d occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m ); - firstfour=1; - } - fprintf(ficlog,"Error! Death for individual %ld line=%d occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m ); + /* death is known but not confirmed by death status at any wave */ + if(firstfour==0){ + printf("Error! Death for individual %ld line=%d occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m ); + firstfour=1; + } + fprintf(ficlog,"Error! Death for individual %ld line=%d occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m ); } - } - wav[i]=mi; + } /* end if date of death is known */ +#endif + wav[i]=mi; /* mi should be the last effective wave (or mli) */ + /* wav[i]=mw[mi][i]; */ if(mi==0){ nbwarn++; if(first==0){ - printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i); - first=1; + printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i); + first=1; } if(first==1){ - fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i); + fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i); } } /* end mi==0 */ } /* End individuals */ /* wav and mw are no more changed */ - + for(i=1; i<=imx; i++){ for(mi=1; mi nlstate) { /* A death */ - if (agedc[i] < 2*AGESUP) { - j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); - if(j==0) j=1; /* Survives at least one month after exam */ - else if(j<0){ - nberr++; - printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); - j=1; /* Temporary Dangerous patch */ - printf(" We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm); - fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); - fprintf(ficlog," We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm); - } - k=k+1; - if (j >= jmax){ - jmax=j; - ijmax=i; - } - if (j <= jmin){ - jmin=j; - ijmin=i; - } - sum=sum+j; - /*if (j<0) printf("j=%d num=%d \n",j,i);*/ - /* printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/ - } - } - else{ - j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12)); + if (s[mw[mi+1][i]][i] > nlstate) { /* A death */ + if (agedc[i] < 2*AGESUP) { + j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); + if(j==0) j=1; /* Survives at least one month after exam */ + else if(j<0){ + nberr++; + printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); + j=1; /* Temporary Dangerous patch */ + printf(" We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm); + fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); + fprintf(ficlog," We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm); + } + k=k+1; + if (j >= jmax){ + jmax=j; + ijmax=i; + } + if (j <= jmin){ + jmin=j; + ijmin=i; + } + sum=sum+j; + /*if (j<0) printf("j=%d num=%d \n",j,i);*/ + /* printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/ + } + } + else{ + j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12)); /* if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */ - - k=k+1; - if (j >= jmax) { - jmax=j; - ijmax=i; - } - else if (j <= jmin){ - jmin=j; - ijmin=i; - } - /* if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */ - /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/ - if(j<0){ - nberr++; - printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); - fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); - } - sum=sum+j; - } - jk= j/stepm; - jl= j -jk*stepm; - ju= j -(jk+1)*stepm; - if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */ - if(jl==0){ - dh[mi][i]=jk; - bh[mi][i]=0; - }else{ /* We want a negative bias in order to only have interpolation ie - * to avoid the price of an extra matrix product in likelihood */ - dh[mi][i]=jk+1; - bh[mi][i]=ju; - } - }else{ - if(jl <= -ju){ - dh[mi][i]=jk; - bh[mi][i]=jl; /* bias is positive if real duration - * is higher than the multiple of stepm and negative otherwise. - */ - } - else{ - dh[mi][i]=jk+1; - bh[mi][i]=ju; - } - if(dh[mi][i]==0){ - dh[mi][i]=1; /* At least one step */ - bh[mi][i]=ju; /* At least one step */ - /* printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/ - } - } /* end if mle */ + + k=k+1; + if (j >= jmax) { + jmax=j; + ijmax=i; + } + else if (j <= jmin){ + jmin=j; + ijmin=i; + } + /* if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */ + /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/ + if(j<0){ + nberr++; + printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); + fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); + } + sum=sum+j; + } + jk= j/stepm; + jl= j -jk*stepm; + ju= j -(jk+1)*stepm; + if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */ + if(jl==0){ + dh[mi][i]=jk; + bh[mi][i]=0; + }else{ /* We want a negative bias in order to only have interpolation ie + * to avoid the price of an extra matrix product in likelihood */ + dh[mi][i]=jk+1; + bh[mi][i]=ju; + } + }else{ + if(jl <= -ju){ + dh[mi][i]=jk; + bh[mi][i]=jl; /* bias is positive if real duration + * is higher than the multiple of stepm and negative otherwise. + */ + } + else{ + dh[mi][i]=jk+1; + bh[mi][i]=ju; + } + if(dh[mi][i]==0){ + dh[mi][i]=1; /* At least one step */ + bh[mi][i]=ju; /* At least one step */ + /* printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/ + } + } /* end if mle */ } } /* end wave */ } @@ -4279,8 +4474,8 @@ void concatwav(int wav[], int **dh, int /**< Uses cptcovn+2*cptcovprod as the number of covariates */ /* Tvar[i]=atoi(stre); find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 * Boring subroutine which should only output nbcode[Tvar[j]][k] - * Tvar[5] in V2+V1+V3*age+V2*V4 is 2 (V2) - * nbcode[Tvar[5]][1]= nbcode[2][1]=0, nbcode[2][2]=1 (usually); + * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable + * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually); */ int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX; @@ -4290,41 +4485,44 @@ void concatwav(int wav[], int **dh, int /* cptcoveff=0; */ - *cptcov=0; + /* *cptcov=0; */ for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */ - /* Loop on covariates without age and products */ - for (j=1; j<=(cptcovs); j++) { /* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only */ + /* Loop on covariates without age and products and no quantitative variable */ + /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */ + for (j=1; j<=(*cptcov); j++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */ for (k=-1; k < maxncov; k++) Ndum[k]=0; for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the - modality of this covariate Vj*/ - ij=(int)(covar[Tvar[j]][i]); /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i - * If product of Vn*Vm, still boolean *: - * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables - * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0 */ - /* Finds for covariate j, n=Tvar[j] of Vn . ij is the - modality of the nth covariate of individual i. */ - if (ij > modmaxcovj) - modmaxcovj=ij; - else if (ij < modmincovj) - modmincovj=ij; - if ((ij < -1) && (ij > NCOVMAX)){ - printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX ); - exit(1); - }else - Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/ + modality of this covariate Vj*/ + if(Tvar[j] >=1 && Tvar[j] <= *cptcov){ /* A real fixed covariate */ + ij=(int)(covar[Tvar[j]][i]); /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i + * If product of Vn*Vm, still boolean *: + * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables + * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0 */ + /* Finds for covariate j, n=Tvar[j] of Vn . ij is the + modality of the nth covariate of individual i. */ + if (ij > modmaxcovj) + modmaxcovj=ij; + else if (ij < modmincovj) + modmincovj=ij; + if ((ij < -1) && (ij > NCOVMAX)){ + printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX ); + exit(1); + }else + Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/ /* If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */ /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/ /* getting the maximum value of the modality of the covariate - (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and - female is 1, then modmaxcovj=1.*/ - } /* end for loop on individuals i */ + (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and + female ies 1, then modmaxcovj=1.*/ + } + } /* end for loop on individuals i */ printf(" Minimal and maximal values of %d th covariate V%d: min=%d max=%d \n", j, Tvar[j], modmincovj, modmaxcovj); fprintf(ficlog," Minimal and maximal values of %d th covariate V%d: min=%d max=%d \n", j, Tvar[j], modmincovj, modmaxcovj); cptcode=modmaxcovj; /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */ - /*for (i=0; i<=cptcode; i++) {*/ + /*for (i=0; i<=cptcode; i++) {*/ for (k=modmincovj; k<=modmaxcovj; k++) { /* k=-1 ? 0 and 1*//* For each value k of the modality of model-cov j */ printf("Frequencies of covariates %d ie V%d with value %d: %d\n", j, Tvar[j], k, Ndum[k]); fprintf(ficlog, "Frequencies of covariates %d ie V%d with value %d: %d\n", j, Tvar[j], k, Ndum[k]); @@ -4339,7 +4537,7 @@ void concatwav(int wav[], int **dh, int undefined. Usually 3: -1, 0 and 1. */ } /* In fact ncodemax[j]=2 (dichotom. variables only) but it could be more for - historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */ + * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */ } /* Ndum[-1] number of undefined modalities */ /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */ @@ -4360,11 +4558,11 @@ void concatwav(int wav[], int **dh, int if (Ndum[i] == 0) { /* If nobody responded to this modality k */ break; } - ij++; - nbcode[Tvar[j]][ij]=i; /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality.*/ - cptcode = ij; /* New max modality for covar j */ + ij++; + nbcode[Tvar[j]][ij]=i; /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality.*/ + cptcode = ij; /* New max modality for covar j */ } /* end of loop on modality i=-1 to 1 or more */ - + /* for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */ /* /\*recode from 0 *\/ */ /* k is a modality. If we have model=V1+V1*sex */ @@ -4386,23 +4584,27 @@ void concatwav(int wav[], int **dh, int /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ ij=Tvar[i]; /* Tvar might be -1 if status was unknown */ Ndum[ij]++; /* Might be supersed V1 + V1*age */ - } + } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */ ij=0; for (i=0; i<= maxncov-1; i++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */ /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/ if((Ndum[i]!=0) && (i<=ncovcol)){ - ij++; /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/ - Tvaraff[ij]=i; /*For printing (unclear) */ - }else{ - /* Tvaraff[ij]=0; */ + Tvaraff[++ij]=i; /*For printing (unclear) */ + }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ + Tvaraff[++ij]=-10; /* Dont'n know how to treat quantitative variables yet */ + }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ + Tvaraff[++ij]=i; /*For printing (unclear) */ + }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ + Tvaraff[++ij]=-20; /* Dont'n know how to treat quantitative variables yet */ } - } + } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */ /* ij--; */ /* cptcoveff=ij; /\*Number of total covariates*\/ */ - *cptcov=ij; /*Number of total covariates*/ - + *cptcov=ij; /*Number of total real effective covariates: effective + * because they can be excluded from the model and real + * if in the model but excluded because missing values*/ } @@ -4520,7 +4722,7 @@ void cvevsij(double ***eij, double x[], { /* Covariances of health expectancies eij and of total life expectancies according - to initial status i, ei. . + to initial status i, ei. . */ int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji; int nhstepma, nstepma; /* Decreasing with age */ @@ -4626,47 +4828,47 @@ void cvevsij(double ***eij, double x[], decrease memory allocation */ for(theta=1; theta <=npar; theta++){ for(i=1; i<=npar; i++){ - xp[i] = x[i] + (i==theta ?delti[theta]:0); - xm[i] = x[i] - (i==theta ?delti[theta]:0); + xp[i] = x[i] + (i==theta ?delti[theta]:0); + xm[i] = x[i] - (i==theta ?delti[theta]:0); } hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij); hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij); for(j=1; j<= nlstate; j++){ - for(i=1; i<=nlstate; i++){ - for(h=0; h<=nhstepm-1; h++){ - gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.; - gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.; - } - } + for(i=1; i<=nlstate; i++){ + for(h=0; h<=nhstepm-1; h++){ + gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.; + gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.; + } + } } for(ij=1; ij<= nlstate*nlstate; ij++) - for(h=0; h<=nhstepm-1; h++){ - gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta]; - } + for(h=0; h<=nhstepm-1; h++){ + gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta]; + } }/* End theta */ for(h=0; h<=nhstepm-1; h++) for(j=1; j<=nlstate*nlstate;j++) - for(theta=1; theta <=npar; theta++) - trgradg[h][j][theta]=gradg[h][theta][j]; + for(theta=1; theta <=npar; theta++) + trgradg[h][j][theta]=gradg[h][theta][j]; - for(ij=1;ij<=nlstate*nlstate;ij++) + for(ij=1;ij<=nlstate*nlstate;ij++) for(ji=1;ji<=nlstate*nlstate;ji++) - varhe[ij][ji][(int)age] =0.; + varhe[ij][ji][(int)age] =0.; - printf("%d|",(int)age);fflush(stdout); - fprintf(ficlog,"%d|",(int)age);fflush(ficlog); - for(h=0;h<=nhstepm-1;h++){ + printf("%d|",(int)age);fflush(stdout); + fprintf(ficlog,"%d|",(int)age);fflush(ficlog); + for(h=0;h<=nhstepm-1;h++){ for(k=0;k<=nhstepm-1;k++){ - matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov); - matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]); - for(ij=1;ij<=nlstate*nlstate;ij++) - for(ji=1;ji<=nlstate*nlstate;ji++) - varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf; + matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov); + matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]); + for(ij=1;ij<=nlstate*nlstate;ij++) + for(ji=1;ji<=nlstate*nlstate;ji++) + varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf; } } @@ -4674,22 +4876,22 @@ void cvevsij(double ***eij, double x[], hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij); for(i=1; i<=nlstate;i++) for(j=1; j<=nlstate;j++) - for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){ - eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf; + for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){ + eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf; - /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/ + /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/ - } + } fprintf(ficresstdeij,"%3.0f",age ); for(i=1; i<=nlstate;i++){ eip=0.; vip=0.; for(j=1; j<=nlstate;j++){ - eip += eij[i][j][(int)age]; - for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */ - vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age]; - fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) ); + eip += eij[i][j][(int)age]; + for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */ + vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age]; + fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) ); } fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip)); } @@ -4698,13 +4900,13 @@ void cvevsij(double ***eij, double x[], fprintf(ficrescveij,"%3.0f",age ); for(i=1; i<=nlstate;i++) for(j=1; j<=nlstate;j++){ - cptj= (j-1)*nlstate+i; - for(i2=1; i2<=nlstate;i2++) - for(j2=1; j2<=nlstate;j2++){ - cptj2= (j2-1)*nlstate+i2; - if(cptj2 <= cptj) - fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]); - } + cptj= (j-1)*nlstate+i; + for(i2=1; i2<=nlstate;i2++) + for(j2=1; j2<=nlstate;j2++){ + cptj2= (j2-1)*nlstate+i2; + if(cptj2 <= cptj) + fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]); + } } fprintf(ficrescveij,"\n"); @@ -5161,86 +5363,86 @@ void cvevsij(double ***eij, double x[], /************ Variance of one-step probabilities ******************/ void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[]) -{ - int i, j=0, k1, l1, tj; - int k2, l2, j1, z1; - int k=0, l; - int first=1, first1, first2; - double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp; - double **dnewm,**doldm; - double *xp; - double *gp, *gm; - double **gradg, **trgradg; - double **mu; - double age, cov[NCOVMAX+1]; - double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */ - int theta; - char fileresprob[FILENAMELENGTH]; - char fileresprobcov[FILENAMELENGTH]; - char fileresprobcor[FILENAMELENGTH]; - double ***varpij; - - strcpy(fileresprob,"PROB_"); - strcat(fileresprob,fileres); - if((ficresprob=fopen(fileresprob,"w"))==NULL) { - printf("Problem with resultfile: %s\n", fileresprob); - fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob); - } - strcpy(fileresprobcov,"PROBCOV_"); - strcat(fileresprobcov,fileresu); - if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) { - printf("Problem with resultfile: %s\n", fileresprobcov); - fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov); - } - strcpy(fileresprobcor,"PROBCOR_"); - strcat(fileresprobcor,fileresu); - if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) { - printf("Problem with resultfile: %s\n", fileresprobcor); - fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor); - } - printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob); - fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob); - printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov); - fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov); - printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor); - fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor); - pstamp(ficresprob); - fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n"); - fprintf(ficresprob,"# Age"); - pstamp(ficresprobcov); - fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n"); - fprintf(ficresprobcov,"# Age"); - pstamp(ficresprobcor); - fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n"); - fprintf(ficresprobcor,"# Age"); - + { + int i, j=0, k1, l1, tj; + int k2, l2, j1, z1; + int k=0, l; + int first=1, first1, first2; + double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp; + double **dnewm,**doldm; + double *xp; + double *gp, *gm; + double **gradg, **trgradg; + double **mu; + double age, cov[NCOVMAX+1]; + double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */ + int theta; + char fileresprob[FILENAMELENGTH]; + char fileresprobcov[FILENAMELENGTH]; + char fileresprobcor[FILENAMELENGTH]; + double ***varpij; + + strcpy(fileresprob,"PROB_"); + strcat(fileresprob,fileres); + if((ficresprob=fopen(fileresprob,"w"))==NULL) { + printf("Problem with resultfile: %s\n", fileresprob); + fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob); + } + strcpy(fileresprobcov,"PROBCOV_"); + strcat(fileresprobcov,fileresu); + if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) { + printf("Problem with resultfile: %s\n", fileresprobcov); + fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov); + } + strcpy(fileresprobcor,"PROBCOR_"); + strcat(fileresprobcor,fileresu); + if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) { + printf("Problem with resultfile: %s\n", fileresprobcor); + fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor); + } + printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob); + fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob); + printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov); + fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov); + printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor); + fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor); + pstamp(ficresprob); + fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n"); + fprintf(ficresprob,"# Age"); + pstamp(ficresprobcov); + fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n"); + fprintf(ficresprobcov,"# Age"); + pstamp(ficresprobcor); + fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n"); + fprintf(ficresprobcor,"# Age"); - for(i=1; i<=nlstate;i++) - for(j=1; j<=(nlstate+ndeath);j++){ - fprintf(ficresprob," p%1d-%1d (SE)",i,j); - fprintf(ficresprobcov," p%1d-%1d ",i,j); - fprintf(ficresprobcor," p%1d-%1d ",i,j); - } - /* fprintf(ficresprob,"\n"); - fprintf(ficresprobcov,"\n"); - fprintf(ficresprobcor,"\n"); - */ - xp=vector(1,npar); - dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar); - doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath)); - mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage); - varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage); - first=1; - fprintf(ficgp,"\n# Routine varprob"); - fprintf(fichtm,"\n

  • Computing and drawing one step probabilities with their confidence intervals

    • \n"); - fprintf(fichtm,"\n"); - fprintf(fichtm,"\n

  • Matrix of variance-covariance of one-step probabilities (drawings)

    this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.
    • \n",optionfilehtmcov); - fprintf(fichtmcov,"Current page is file %s
    \n\n

    Matrix of variance-covariance of pairs of step probabilities

    \n",optionfilehtmcov, optionfilehtmcov); - fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (pij, pkl) are estimated \ + for(i=1; i<=nlstate;i++) + for(j=1; j<=(nlstate+ndeath);j++){ + fprintf(ficresprob," p%1d-%1d (SE)",i,j); + fprintf(ficresprobcov," p%1d-%1d ",i,j); + fprintf(ficresprobcor," p%1d-%1d ",i,j); + } + /* fprintf(ficresprob,"\n"); + fprintf(ficresprobcov,"\n"); + fprintf(ficresprobcor,"\n"); + */ + xp=vector(1,npar); + dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar); + doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath)); + mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage); + varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage); + first=1; + fprintf(ficgp,"\n# Routine varprob"); + fprintf(fichtm,"\n

  • Computing and drawing one step probabilities with their confidence intervals

    • \n"); + fprintf(fichtm,"\n"); + + fprintf(fichtm,"\n

  • Matrix of variance-covariance of one-step probabilities (drawings)

    this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.
    • \n",optionfilehtmcov); + fprintf(fichtmcov,"Current page is file %s
    \n\n

    Matrix of variance-covariance of pairs of step probabilities

    \n",optionfilehtmcov, optionfilehtmcov); + fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (pij, pkl) are estimated \ and drawn. It helps understanding how is the covariance between two incidences.\ They are expressed in year-1 in order to be less dependent of stepm.
    \n"); - fprintf(fichtmcov,"\n
    Contour plot corresponding to x'cov-1x = 4 (where x is the column vector (pij,pkl)) are drawn. \ + fprintf(fichtmcov,"\n
    Contour plot corresponding to x'cov-1x = 4 (where x is the column vector (pij,pkl)) are drawn. \ It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \ would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \ standard deviations wide on each axis.
    \ @@ -5248,252 +5450,252 @@ standard deviations wide on each axis. < and made the appropriate rotation to look at the uncorrelated principal directions.
    \ To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.
    \n"); - cov[1]=1; - /* tj=cptcoveff; */ - tj = (int) pow(2,cptcoveff); - if (cptcovn<1) {tj=1;ncodemax[1]=1;} - j1=0; - for(j1=1; j1<=tj;j1++){ /* For each valid combination of covariates */ - if (cptcovn>0) { - fprintf(ficresprob, "\n#********** Variable "); - for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]); - fprintf(ficresprob, "**********\n#\n"); - fprintf(ficresprobcov, "\n#********** Variable "); - for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]); - fprintf(ficresprobcov, "**********\n#\n"); + cov[1]=1; + /* tj=cptcoveff; */ + tj = (int) pow(2,nqveff); + if (cptcovn<1) {tj=1;ncodemax[1]=1;} + j1=0; + for(j1=1; j1<=tj;j1++){ /* For each valid combination of covariates or only once*/ + if (cptcovn>0) { + fprintf(ficresprob, "\n#********** Variable "); + for (z1=1; z1<=nqveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]); + fprintf(ficresprob, "**********\n#\n"); + fprintf(ficresprobcov, "\n#********** Variable "); + for (z1=1; z1<=nqveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]); + fprintf(ficresprobcov, "**********\n#\n"); - fprintf(ficgp, "\n#********** Variable "); - for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]); - fprintf(ficgp, "**********\n#\n"); + fprintf(ficgp, "\n#********** Variable "); + for (z1=1; z1<=nqveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]); + fprintf(ficgp, "**********\n#\n"); - fprintf(fichtmcov, "\n
    ********** Variable "); - for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]); - fprintf(fichtmcov, "**********\n
    "); + fprintf(fichtmcov, "\n
    ********** Variable "); + for (z1=1; z1<=nqveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]); + fprintf(fichtmcov, "**********\n
    "); - fprintf(ficresprobcor, "\n#********** Variable "); - for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]); - fprintf(ficresprobcor, "**********\n#"); - if(invalidvarcomb[j1]){ - fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); - fprintf(fichtmcov,"\n

    Combination (%d) ignored because no cases

    \n",j1); - continue; - } - } - gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath)); - trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar); - gp=vector(1,(nlstate)*(nlstate+ndeath)); - gm=vector(1,(nlstate)*(nlstate+ndeath)); - for (age=bage; age<=fage; age ++){ - cov[2]=age; - if(nagesqr==1) - cov[3]= age*age; - for (k=1; k<=cptcovn;k++) { - cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)]; - /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4 - * 1 1 1 1 1 - * 2 2 1 1 1 - * 3 1 2 1 1 - */ - /* nbcode[1][1]=0 nbcode[1][2]=1;*/ - } - /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */ - for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; - for (k=1; k<=cptcovprod;k++) - cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; + fprintf(ficresprobcor, "\n#********** Variable "); + for (z1=1; z1<=nqveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]); + fprintf(ficresprobcor, "**********\n#"); + if(invalidvarcomb[j1]){ + fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); + fprintf(fichtmcov,"\n

    Combination (%d) ignored because no cases

    \n",j1); + continue; + } + } + gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath)); + trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar); + gp=vector(1,(nlstate)*(nlstate+ndeath)); + gm=vector(1,(nlstate)*(nlstate+ndeath)); + for (age=bage; age<=fage; age ++){ + cov[2]=age; + if(nagesqr==1) + cov[3]= age*age; + for (k=1; k<=cptcovn;k++) { + cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)]; + /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4 + * 1 1 1 1 1 + * 2 2 1 1 1 + * 3 1 2 1 1 + */ + /* nbcode[1][1]=0 nbcode[1][2]=1;*/ + } + /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */ + for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; + for (k=1; k<=cptcovprod;k++) + cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; - for(theta=1; theta <=npar; theta++){ - for(i=1; i<=npar; i++) - xp[i] = x[i] + (i==theta ?delti[theta]:(double)0); + for(theta=1; theta <=npar; theta++){ + for(i=1; i<=npar; i++) + xp[i] = x[i] + (i==theta ?delti[theta]:(double)0); - pmij(pmmij,cov,ncovmodel,xp,nlstate); + pmij(pmmij,cov,ncovmodel,xp,nlstate); - k=0; - for(i=1; i<= (nlstate); i++){ - for(j=1; j<=(nlstate+ndeath);j++){ - k=k+1; - gp[k]=pmmij[i][j]; - } - } + k=0; + for(i=1; i<= (nlstate); i++){ + for(j=1; j<=(nlstate+ndeath);j++){ + k=k+1; + gp[k]=pmmij[i][j]; + } + } - for(i=1; i<=npar; i++) - xp[i] = x[i] - (i==theta ?delti[theta]:(double)0); + for(i=1; i<=npar; i++) + xp[i] = x[i] - (i==theta ?delti[theta]:(double)0); - pmij(pmmij,cov,ncovmodel,xp,nlstate); - k=0; - for(i=1; i<=(nlstate); i++){ - for(j=1; j<=(nlstate+ndeath);j++){ - k=k+1; - gm[k]=pmmij[i][j]; - } - } + pmij(pmmij,cov,ncovmodel,xp,nlstate); + k=0; + for(i=1; i<=(nlstate); i++){ + for(j=1; j<=(nlstate+ndeath);j++){ + k=k+1; + gm[k]=pmmij[i][j]; + } + } - for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) - gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta]; - } + for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) + gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta]; + } - for(j=1; j<=(nlstate)*(nlstate+ndeath);j++) - for(theta=1; theta <=npar; theta++) - trgradg[j][theta]=gradg[theta][j]; + for(j=1; j<=(nlstate)*(nlstate+ndeath);j++) + for(theta=1; theta <=npar; theta++) + trgradg[j][theta]=gradg[theta][j]; - matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); - matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg); + matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); + matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg); - pmij(pmmij,cov,ncovmodel,x,nlstate); + pmij(pmmij,cov,ncovmodel,x,nlstate); - k=0; - for(i=1; i<=(nlstate); i++){ - for(j=1; j<=(nlstate+ndeath);j++){ - k=k+1; - mu[k][(int) age]=pmmij[i][j]; - } - } - for(i=1;i<=(nlstate)*(nlstate+ndeath);i++) - for(j=1;j<=(nlstate)*(nlstate+ndeath);j++) - varpij[i][j][(int)age] = doldm[i][j]; + k=0; + for(i=1; i<=(nlstate); i++){ + for(j=1; j<=(nlstate+ndeath);j++){ + k=k+1; + mu[k][(int) age]=pmmij[i][j]; + } + } + for(i=1;i<=(nlstate)*(nlstate+ndeath);i++) + for(j=1;j<=(nlstate)*(nlstate+ndeath);j++) + varpij[i][j][(int)age] = doldm[i][j]; - /*printf("\n%d ",(int)age); - for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){ - printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i])); - fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i])); - }*/ + /*printf("\n%d ",(int)age); + for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){ + printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i])); + fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i])); + }*/ - fprintf(ficresprob,"\n%d ",(int)age); - fprintf(ficresprobcov,"\n%d ",(int)age); - fprintf(ficresprobcor,"\n%d ",(int)age); + fprintf(ficresprob,"\n%d ",(int)age); + fprintf(ficresprobcov,"\n%d ",(int)age); + fprintf(ficresprobcor,"\n%d ",(int)age); - for (i=1; i<=(nlstate)*(nlstate+ndeath);i++) - fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age])); - for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){ - fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]); - fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]); - } - i=0; - for (k=1; k<=(nlstate);k++){ - for (l=1; l<=(nlstate+ndeath);l++){ - i++; - fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l); - fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l); - for (j=1; j<=i;j++){ - /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */ - fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]); - fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age])); - } - } - }/* end of loop for state */ - } /* end of loop for age */ - free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath)); - free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath)); - free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar); - free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar); - - /* Confidence intervalle of pij */ - /* - fprintf(ficgp,"\nunset parametric;unset label"); - fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\""); - fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65"); - fprintf(fichtm,"\n
    Probability with confidence intervals expressed in year-1 :pijgr%s.png, ",optionfilefiname,optionfilefiname); - fprintf(fichtm,"\n
    ",optionfilefiname); - fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname); - fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob); - */ - - /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/ - first1=1;first2=2; - for (k2=1; k2<=(nlstate);k2++){ - for (l2=1; l2<=(nlstate+ndeath);l2++){ - if(l2==k2) continue; - j=(k2-1)*(nlstate+ndeath)+l2; - for (k1=1; k1<=(nlstate);k1++){ - for (l1=1; l1<=(nlstate+ndeath);l1++){ - if(l1==k1) continue; - i=(k1-1)*(nlstate+ndeath)+l1; - if(i<=j) continue; - for (age=bage; age<=fage; age ++){ - if ((int)age %5==0){ - v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM; - v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM; - cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM; - mu1=mu[i][(int) age]/stepm*YEARM ; - mu2=mu[j][(int) age]/stepm*YEARM; - c12=cv12/sqrt(v1*v2); - /* Computing eigen value of matrix of covariance */ - lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.; - lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.; - if ((lc2 <0) || (lc1 <0) ){ - if(first2==1){ - first1=0; - printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor); - } - fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog); - /* lc1=fabs(lc1); */ /* If we want to have them positive */ - /* lc2=fabs(lc2); */ - } + for (i=1; i<=(nlstate)*(nlstate+ndeath);i++) + fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age])); + for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){ + fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]); + fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]); + } + i=0; + for (k=1; k<=(nlstate);k++){ + for (l=1; l<=(nlstate+ndeath);l++){ + i++; + fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l); + fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l); + for (j=1; j<=i;j++){ + /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */ + fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]); + fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age])); + } + } + }/* end of loop for state */ + } /* end of loop for age */ + free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath)); + free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath)); + free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar); + free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar); + + /* Confidence intervalle of pij */ + /* + fprintf(ficgp,"\nunset parametric;unset label"); + fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\""); + fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65"); + fprintf(fichtm,"\n
    Probability with confidence intervals expressed in year-1 :pijgr%s.png, ",optionfilefiname,optionfilefiname); + fprintf(fichtm,"\n
    ",optionfilefiname); + fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname); + fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob); + */ + + /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/ + first1=1;first2=2; + for (k2=1; k2<=(nlstate);k2++){ + for (l2=1; l2<=(nlstate+ndeath);l2++){ + if(l2==k2) continue; + j=(k2-1)*(nlstate+ndeath)+l2; + for (k1=1; k1<=(nlstate);k1++){ + for (l1=1; l1<=(nlstate+ndeath);l1++){ + if(l1==k1) continue; + i=(k1-1)*(nlstate+ndeath)+l1; + if(i<=j) continue; + for (age=bage; age<=fage; age ++){ + if ((int)age %5==0){ + v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM; + v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM; + cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM; + mu1=mu[i][(int) age]/stepm*YEARM ; + mu2=mu[j][(int) age]/stepm*YEARM; + c12=cv12/sqrt(v1*v2); + /* Computing eigen value of matrix of covariance */ + lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.; + lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.; + if ((lc2 <0) || (lc1 <0) ){ + if(first2==1){ + first1=0; + printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor); + } + fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog); + /* lc1=fabs(lc1); */ /* If we want to have them positive */ + /* lc2=fabs(lc2); */ + } - /* Eigen vectors */ - v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12)); - /*v21=sqrt(1.-v11*v11); *//* error */ - v21=(lc1-v1)/cv12*v11; - v12=-v21; - v22=v11; - tnalp=v21/v11; - if(first1==1){ - first1=0; - printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp); - } - fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp); - /*printf(fignu*/ - /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */ - /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */ - if(first==1){ - first=0; - fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n"); - fprintf(ficgp,"\nset parametric;unset label"); - fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2); - fprintf(ficgp,"\nset ter svg size 640, 480"); - fprintf(fichtmcov,"\n
    Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year-1\ + /* Eigen vectors */ + v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12)); + /*v21=sqrt(1.-v11*v11); *//* error */ + v21=(lc1-v1)/cv12*v11; + v12=-v21; + v22=v11; + tnalp=v21/v11; + if(first1==1){ + first1=0; + printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp); + } + fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp); + /*printf(fignu*/ + /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */ + /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */ + if(first==1){ + first=0; + fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n"); + fprintf(ficgp,"\nset parametric;unset label"); + fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2); + fprintf(ficgp,"\nset ter svg size 640, 480"); + fprintf(fichtmcov,"\n
    Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year-1\ : \ %s_%d%1d%1d-%1d%1d.svg, ",k1,l1,k2,l2,\ - subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2, \ - subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2); - fprintf(fichtmcov,"\n
    ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2); - fprintf(fichtmcov,"\n
    Correlation at age %d (%.3f),",(int) age, c12); - fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2); - fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2); - fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2); - fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \ - mu1,std,v11,sqrt(lc1),v12,sqrt(lc2), \ - mu2,std,v21,sqrt(lc1),v22,sqrt(lc2)); - }else{ - first=0; - fprintf(fichtmcov," %d (%.3f),",(int) age, c12); - fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2); - fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2); - fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \ - mu1,std,v11,sqrt(lc1),v12,sqrt(lc2), \ - mu2,std,v21,sqrt(lc1),v22,sqrt(lc2)); - }/* if first */ - } /* age mod 5 */ - } /* end loop age */ - fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2); - first=1; - } /*l12 */ - } /* k12 */ - } /*l1 */ - }/* k1 */ - } /* loop on combination of covariates j1 */ - free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage); - free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage); - free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath)); - free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar); - free_vector(xp,1,npar); - fclose(ficresprob); - fclose(ficresprobcov); - fclose(ficresprobcor); - fflush(ficgp); - fflush(fichtmcov); -} + subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2, \ + subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2); + fprintf(fichtmcov,"\n
    ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2); + fprintf(fichtmcov,"\n
    Correlation at age %d (%.3f),",(int) age, c12); + fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2); + fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2); + fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2); + fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \ + mu1,std,v11,sqrt(lc1),v12,sqrt(lc2), \ + mu2,std,v21,sqrt(lc1),v22,sqrt(lc2)); + }else{ + first=0; + fprintf(fichtmcov," %d (%.3f),",(int) age, c12); + fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2); + fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2); + fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \ + mu1,std,v11,sqrt(lc1),v12,sqrt(lc2), \ + mu2,std,v21,sqrt(lc1),v22,sqrt(lc2)); + }/* if first */ + } /* age mod 5 */ + } /* end loop age */ + fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2); + first=1; + } /*l12 */ + } /* k12 */ + } /*l1 */ + }/* k1 */ + } /* loop on combination of covariates j1 */ + free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage); + free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage); + free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath)); + free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar); + free_vector(xp,1,npar); + fclose(ficresprob); + fclose(ficresprobcov); + fclose(ficresprobcor); + fflush(ficgp); + fflush(fichtmcov); + } /******************* Printing html file ***********/ @@ -5536,81 +5738,81 @@ void printinghtml(char fileresu[], char %s
    \n", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_")); } -fprintf(fichtm," \n
    • Graphs

      • "); + fprintf(fichtm," \n

      • Graphs

        • "); - m=pow(2,cptcoveff); - if (cptcovn < 1) {m=1;ncodemax[1]=1;} + m=pow(2,nqveff); + if (cptcovn < 1) {m=1;ncodemax[1]=1;} - jj1=0; - for(k1=1; k1<=m;k1++){ + jj1=0; + for(k1=1; k1<=m;k1++){ - /* for(i1=1; i1<=ncodemax[k1];i1++){ */ - jj1++; - if (cptcovn > 0) { - fprintf(fichtm,"

        ************ Results for covariates"); - for (cpt=1; cpt<=cptcoveff;cpt++){ - fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); - printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); - } - fprintf(fichtm," ************\n
        "); - if(invalidvarcomb[k1]){ - fprintf(fichtm,"\n

        Combination (%d) ignored because no cases

        \n",k1); - printf("\nCombination (%d) ignored because no cases \n",k1); - continue; - } - } - /* aij, bij */ - fprintf(fichtm,"
        - Logit model (yours is: 1+age+%s), for example: logit(pij)=log(pij/pii)= aij+ bij age + V1 age + etc. as a function of age: %s_%d-1.svg
        \ + /* for(i1=1; i1<=ncodemax[k1];i1++){ */ + jj1++; + if (cptcovn > 0) { + fprintf(fichtm,"
        ************ Results for covariates"); + for (cpt=1; cpt<=nqveff;cpt++){ + fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); + printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); + } + fprintf(fichtm," ************\n
        "); + if(invalidvarcomb[k1]){ + fprintf(fichtm,"\n

        Combination (%d) ignored because no cases

        \n",k1); + printf("\nCombination (%d) ignored because no cases \n",k1); + continue; + } + } + /* aij, bij */ + fprintf(fichtm,"
        - Logit model (yours is: 1+age+%s), for example: logit(pij)=log(pij/pii)= aij+ bij age + V1 age + etc. as a function of age: %s_%d-1.svg
        \ ",model,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1); - /* Pij */ - fprintf(fichtm,"
        \n- Pij or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: %s_%d-2.svg
        \ + /* Pij */ + fprintf(fichtm,"
        \n- Pij or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: %s_%d-2.svg
        \ ",stepm,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1); - /* Quasi-incidences */ - fprintf(fichtm,"
        \n- Iij or Conditional probabilities to be observed in state j being in state i %d (stepm) months\ + /* Quasi-incidences */ + fprintf(fichtm,"
        \n- Iij or Conditional probabilities to be observed in state j being in state i %d (stepm) months\ before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \ incidence (rates) are the limit when h tends to zero of the ratio of the probability hPij \ divided by h: hPij/h : %s_%d-3.svg
        \ ",stepm,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1); - /* Survival functions (period) in state j */ - for(cpt=1; cpt<=nlstate;cpt++){ - fprintf(fichtm,"
        \n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. %s%d_%d.svg
        \ + /* Survival functions (period) in state j */ + for(cpt=1; cpt<=nlstate;cpt++){ + fprintf(fichtm,"
        \n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. %s%d_%d.svg
        \ ", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,jj1,subdirf2(optionfilefiname,"LIJ_"),cpt,jj1,subdirf2(optionfilefiname,"LIJ_"),cpt,jj1); - } - /* State specific survival functions (period) */ - for(cpt=1; cpt<=nlstate;cpt++){ - fprintf(fichtm,"
        \n- Survival functions from state %d in each live state and total.\ + } + /* State specific survival functions (period) */ + for(cpt=1; cpt<=nlstate;cpt++){ + fprintf(fichtm,"
        \n- Survival functions from state %d in each live state and total.\ Or probability to survive in various states (1 to %d) being in state %d at different ages. \ %s%d_%d.svg
        ", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,jj1,subdirf2(optionfilefiname,"LIJT_"),cpt,jj1,subdirf2(optionfilefiname,"LIJT_"),cpt,jj1); - } - /* Period (stable) prevalence in each health state */ - for(cpt=1; cpt<=nlstate;cpt++){ - fprintf(fichtm,"
        \n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. %s_%d-%d.svg
        \ -", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,jj1,subdirf2(optionfilefiname,"P_"),cpt,jj1,subdirf2(optionfilefiname,"P_"),cpt,jj1); - } - if(backcast==1){ - /* Period (stable) back prevalence in each health state */ + } + /* Period (stable) prevalence in each health state */ for(cpt=1; cpt<=nlstate;cpt++){ - fprintf(fichtm,"
        \n- Convergence to period (stable) back prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. %s_%d-%d.svg
        \ + fprintf(fichtm,"
        \n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. %s_%d-%d.svg
        \ +", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,jj1,subdirf2(optionfilefiname,"P_"),cpt,jj1,subdirf2(optionfilefiname,"P_"),cpt,jj1); + } + if(backcast==1){ + /* Period (stable) back prevalence in each health state */ + for(cpt=1; cpt<=nlstate;cpt++){ + fprintf(fichtm,"
        \n- Convergence to period (stable) back prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. %s_%d-%d.svg
        \ ", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,jj1,subdirf2(optionfilefiname,"PB_"),cpt,jj1,subdirf2(optionfilefiname,"PB_"),cpt,jj1); + } } - } - if(prevfcast==1){ - /* Projection of prevalence up to period (stable) prevalence in each health state */ - for(cpt=1; cpt<=nlstate;cpt++){ - fprintf(fichtm,"
        \n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f) up to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. %s%d_%d.svg
        \ + if(prevfcast==1){ + /* Projection of prevalence up to period (stable) prevalence in each health state */ + for(cpt=1; cpt<=nlstate;cpt++){ + fprintf(fichtm,"
        \n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f) up to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. %s%d_%d.svg
        \ ", dateprev1, dateprev2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,jj1,subdirf2(optionfilefiname,"PROJ_"),cpt,jj1,subdirf2(optionfilefiname,"PROJ_"),cpt,jj1); - } - } + } + } - for(cpt=1; cpt<=nlstate;cpt++) { - fprintf(fichtm,"\n
        - Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): %s_%d%d.svg
        \ + for(cpt=1; cpt<=nlstate;cpt++) { + fprintf(fichtm,"\n
        - Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): %s_%d%d.svg
        \ ",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,jj1,subdirf2(optionfilefiname,"EXP_"),cpt,jj1,subdirf2(optionfilefiname,"EXP_"),cpt,jj1); - } - /* } /\* end i1 *\/ */ - }/* End k1 */ - fprintf(fichtm,"
      "); + } + /* } /\* end i1 *\/ */ + }/* End k1 */ + fprintf(fichtm,"
    "); - fprintf(fichtm,"\ + fprintf(fichtm,"\ \n

  • Result files (second order: variances)

    \n\ - Parameter file with estimated parameters and covariance matrix: %s
    \ - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).
    \ @@ -5622,32 +5824,32 @@ variances but at the covariance matrix. covariance matrix of the one-step probabilities. \ See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres); - fprintf(fichtm," - Standard deviation of one-step probabilities: %s
    \n", - subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_")); - fprintf(fichtm,"\ + fprintf(fichtm," - Standard deviation of one-step probabilities: %s
    \n", + subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_")); + fprintf(fichtm,"\ - Variance-covariance of one-step probabilities: %s
    \n", - subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_")); + subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_")); - fprintf(fichtm,"\ + fprintf(fichtm,"\ - Correlation matrix of one-step probabilities: %s
    \n", - subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_")); - fprintf(fichtm,"\ + subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_")); + fprintf(fichtm,"\ - Variances and covariances of health expectancies by age and initial health status (cov(eij,ekl)(estepm=%2d months): \ %s
    \n
    • ", estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_")); - fprintf(fichtm,"\ + fprintf(fichtm,"\ - (a) Health expectancies by health status at initial age (eij) and standard errors (in parentheses) (b) life expectancies and standard errors (ei.=ei1+ei2+...)(estepm=%2d months): \ %s
    \n", estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_")); - fprintf(fichtm,"\ + fprintf(fichtm,"\ - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), eij are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): %s
    \n", - estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_")); - fprintf(fichtm,"\ + estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_")); + fprintf(fichtm,"\ - Total life expectancy and total health expectancies to be spent in each health state e.j with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): %s
    \n", - estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_")); - fprintf(fichtm,"\ + estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_")); + fprintf(fichtm,"\ - Standard deviation of period (stable) prevalences: %s
    \n",\ - subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_")); + subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_")); /* if(popforecast==1) fprintf(fichtm,"\n */ /* - Prevalences forecasting: f%s
    \n */ @@ -5655,26 +5857,26 @@ See page 'Matrix of variance-covariance /*
    ",fileres,fileres,fileres,fileres); */ /* else */ /* fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)

    \n",popforecast, stepm, model); */ - fflush(fichtm); - fprintf(fichtm,"
    • Graphs

      • "); + fflush(fichtm); + fprintf(fichtm,"

      • Graphs

        • "); - m=pow(2,cptcoveff); - if (cptcovn < 1) {m=1;ncodemax[1]=1;} + m=pow(2,nqveff); + if (cptcovn < 1) {m=1;ncodemax[1]=1;} - jj1=0; - for(k1=1; k1<=m;k1++){ - /* for(i1=1; i1<=ncodemax[k1];i1++){ */ - jj1++; + jj1=0; + for(k1=1; k1<=m;k1++){ + /* for(i1=1; i1<=ncodemax[k1];i1++){ */ + jj1++; if (cptcovn > 0) { fprintf(fichtm,"

        ************ Results for covariates"); - for (cpt=1; cpt<=cptcoveff;cpt++) - fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); + for (cpt=1; cpt<=nqveff;cpt++) + fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); fprintf(fichtm," ************\n
        "); - if(invalidvarcomb[k1]){ - fprintf(fichtm,"\n

        Combination (%d) ignored because no cases

        \n",k1); - continue; - } + if(invalidvarcomb[k1]){ + fprintf(fichtm,"\n

        Combination (%d) ignored because no cases

        \n",k1); + continue; + } } for(cpt=1; cpt<=nlstate;cpt++) { fprintf(fichtm,"\n
        - Observed (cross-sectional) and period (incidence based) \ @@ -5687,22 +5889,22 @@ true period expectancies (those weighted drawn in addition to the population based expectancies computed using\ observed and cahotic prevalences: %s_%d.svg\n
        \ ",subdirf2(optionfilefiname,"E_"),jj1,subdirf2(optionfilefiname,"E_"),jj1,subdirf2(optionfilefiname,"E_"),jj1); - /* } /\* end i1 *\/ */ - }/* End k1 */ - fprintf(fichtm,"
      "); - fflush(fichtm); + /* } /\* end i1 *\/ */ + }/* End k1 */ + fprintf(fichtm,"
    "); + fflush(fichtm); } /******************* Gnuplot file **************/ - void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[]){ +void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[]){ char dirfileres[132],optfileres[132]; - char gplotcondition[132]; + char gplotcondition[132]; int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,ij=0,l=0; int lv=0, vlv=0, kl=0; int ng=0; int vpopbased; - int ioffset; /* variable offset for columns */ + int ioffset; /* variable offset for columns */ /* if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */ /* printf("Problem with file %s",optionfilegnuplot); */ @@ -5711,158 +5913,162 @@ true period expectancies (those weighted /*#ifdef windows */ fprintf(ficgp,"cd \"%s\" \n",pathc); - /*#endif */ - m=pow(2,cptcoveff); + /*#endif */ + m=pow(2,nqveff); /* Contribution to likelihood */ /* Plot the probability implied in the likelihood */ - fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n"); - fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";"); - /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */ - fprintf(ficgp,"\nset ter pngcairo size 640, 480"); + fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n"); + fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";"); + /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */ + fprintf(ficgp,"\nset ter pngcairo size 640, 480"); /* nice for mle=4 plot by number of matrix products. replot "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */ /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)" */ - /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */ - fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_")); - fprintf(ficgp,"\nset log y;plot \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk)); - fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_")); - fprintf(ficgp,"\nset log y;plot \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk)); - for (i=1; i<= nlstate ; i ++) { - fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i); - fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot \"%s\"",subdirf(fileresilk)); - fprintf(ficgp," u 2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1); - for (j=2; j<= nlstate+ndeath ; j ++) { - fprintf(ficgp,",\\\n \"\" u 2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j); - } - fprintf(ficgp,";\nset out; unset ylabel;\n"); - } - /* unset log; plot "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */ - /* fprintf(ficgp,"\nset log y;plot \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */ - /* fprintf(ficgp,"\nreplot \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */ - fprintf(ficgp,"\nset out;unset log\n"); - /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */ + /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */ + fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_")); + fprintf(ficgp,"\nset log y;plot \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk)); + fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_")); + fprintf(ficgp,"\nset log y;plot \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk)); + for (i=1; i<= nlstate ; i ++) { + fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i); + fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot \"%s\"",subdirf(fileresilk)); + fprintf(ficgp," u 2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1); + for (j=2; j<= nlstate+ndeath ; j ++) { + fprintf(ficgp,",\\\n \"\" u 2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j); + } + fprintf(ficgp,";\nset out; unset ylabel;\n"); + } + /* unset log; plot "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */ + /* fprintf(ficgp,"\nset log y;plot \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */ + /* fprintf(ficgp,"\nreplot \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */ + fprintf(ficgp,"\nset out;unset log\n"); + /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */ strcpy(dirfileres,optionfilefiname); strcpy(optfileres,"vpl"); - /* 1eme*/ + /* 1eme*/ for (cpt=1; cpt<= nlstate ; cpt ++) { /* For each live state */ for (k1=1; k1<= m ; k1 ++) { /* For each valid combination of covariate */ /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */ fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files "); - for (k=1; k<=cptcoveff; k++){ /* For each covariate k get corresponding value lv for combination k1 */ - lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */ - /* decodtabm(1,1,4) = 1 because h=1 k= (1) 1 1 1 */ - /* decodtabm(1,2,4) = 1 because h=1 k= 1 (1) 1 1 */ - /* decodtabm(13,3,4)= 2 because h=13 k= 1 1 (2) 2 */ - vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */ - /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */ - fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv); + for (k=1; k<=nqveff; k++){ /* For each covariate k get corresponding value lv for combination k1 */ + lv= decodtabm(k1,k,nqveff); /* Should be the value of the covariate corresponding to k1 combination */ + /* decodtabm(1,1,4) = 1 because h=1 k= (1) 1 1 1 */ + /* decodtabm(1,2,4) = 1 because h=1 k= 1 (1) 1 1 */ + /* decodtabm(13,3,4)= 2 because h=13 k= 1 1 (2) 2 */ + vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */ + /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */ + fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv); } fprintf(ficgp,"\n#\n"); - if(invalidvarcomb[k1]){ - fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); - continue; - } + if(invalidvarcomb[k1]){ + fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); + continue; + } - fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1); - fprintf(ficgp,"\n#set out \"V_%s_%d-%d.svg\" \n",optionfilefiname,cpt,k1); - fprintf(ficgp,"set xlabel \"Age\" \n\ + fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1); + fprintf(ficgp,"\n#set out \"V_%s_%d-%d.svg\" \n",optionfilefiname,cpt,k1); + fprintf(ficgp,"set xlabel \"Age\" \n\ set ylabel \"Probability\" \n \ set ter svg size 640, 480\n \ plot [%.f:%.f] \"%s\" every :::%d::%d u 1:2 \"%%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1); - for (i=1; i<= nlstate ; i ++) { - if (i==cpt) fprintf(ficgp," %%lf (%%lf)"); - else fprintf(ficgp," %%*lf (%%*lf)"); - } - fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2+1.96*$3) \"%%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1); - for (i=1; i<= nlstate ; i ++) { - if (i==cpt) fprintf(ficgp," %%lf (%%lf)"); - else fprintf(ficgp," %%*lf (%%*lf)"); - } - fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2-1.96*$3) \"%%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1); - for (i=1; i<= nlstate ; i ++) { - if (i==cpt) fprintf(ficgp," %%lf (%%lf)"); - else fprintf(ficgp," %%*lf (%%*lf)"); - } - fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); - if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */ - /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */ - fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1 */ - kl=0; - for (k=1; k<=cptcoveff; k++){ /* For each combination of covariate */ - lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */ - /* decodtabm(1,1,4) = 1 because h=1 k= (1) 1 1 1 */ - /* decodtabm(1,2,4) = 1 because h=1 k= 1 (1) 1 1 */ - /* decodtabm(13,3,4)= 2 because h=13 k= 1 1 (2) 2 */ - vlv= nbcode[Tvaraff[k]][lv]; - kl++; - /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */ - /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ - /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ - /* '' u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/ - if(k==cptcoveff){ - fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' with line ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \ - 6+(cpt-1), cpt ); - }else{ - fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]); - kl++; - } - } /* end covariate */ - } - fprintf(ficgp,"\nset out \n"); + for (i=1; i<= nlstate ; i ++) { + if (i==cpt) fprintf(ficgp," %%lf (%%lf)"); + else fprintf(ficgp," %%*lf (%%*lf)"); + } + fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2+1.96*$3) \"%%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1); + for (i=1; i<= nlstate ; i ++) { + if (i==cpt) fprintf(ficgp," %%lf (%%lf)"); + else fprintf(ficgp," %%*lf (%%*lf)"); + } + fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2-1.96*$3) \"%%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1); + for (i=1; i<= nlstate ; i ++) { + if (i==cpt) fprintf(ficgp," %%lf (%%lf)"); + else fprintf(ficgp," %%*lf (%%*lf)"); + } + fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); + if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */ + /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */ + fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1 */ + if(nqveff ==0){ + fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line ", 2+(cpt-1), cpt ); + }else{ + kl=0; + for (k=1; k<=nqveff; k++){ /* For each combination of covariate */ + lv= decodtabm(k1,k,nqveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */ + /* decodtabm(1,1,4) = 1 because h=1 k= (1) 1 1 1 */ + /* decodtabm(1,2,4) = 1 because h=1 k= 1 (1) 1 1 */ + /* decodtabm(13,3,4)= 2 because h=13 k= 1 1 (2) 2 */ + vlv= nbcode[Tvaraff[k]][lv]; + kl++; + /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */ + /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ + /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ + /* '' u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/ + if(k==nqveff){ + fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' with line ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \ + 6+(cpt-1), cpt ); + }else{ + fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]); + kl++; + } + } /* end covariate */ + } /* end if no covariate */ + } /* end if backcast */ + fprintf(ficgp,"\nset out \n"); } /* k1 */ } /* cpt */ /*2 eme*/ for (k1=1; k1<= m ; k1 ++) { - fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files "); - for (k=1; k<=cptcoveff; k++){ /* For each covariate and each value */ - lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */ - /* decodtabm(1,1,4) = 1 because h=1 k= (1) 1 1 1 */ - /* decodtabm(1,2,4) = 1 because h=1 k= 1 (1) 1 1 */ - /* decodtabm(13,3,4)= 2 because h=13 k= 1 1 (2) 2 */ - vlv= nbcode[Tvaraff[k]][lv]; - fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv); - } - fprintf(ficgp,"\n#\n"); - if(invalidvarcomb[k1]){ - fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); - continue; - } + fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files "); + for (k=1; k<=nqveff; k++){ /* For each covariate and each value */ + lv= decodtabm(k1,k,nqveff); /* Should be the covariate number corresponding to k1 combination */ + /* decodtabm(1,1,4) = 1 because h=1 k= (1) 1 1 1 */ + /* decodtabm(1,2,4) = 1 because h=1 k= 1 (1) 1 1 */ + /* decodtabm(13,3,4)= 2 because h=13 k= 1 1 (2) 2 */ + vlv= nbcode[Tvaraff[k]][lv]; + fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv); + } + fprintf(ficgp,"\n#\n"); + if(invalidvarcomb[k1]){ + fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); + continue; + } - fprintf(ficgp,"\nset out \"%s_%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1); - for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/ - if(vpopbased==0) - fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage); - else - fprintf(ficgp,"\nreplot "); - for (i=1; i<= nlstate+1 ; i ++) { - k=2*i; - fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1, vpopbased); - for (j=1; j<= nlstate+1 ; j ++) { - if (j==i) fprintf(ficgp," %%lf (%%lf)"); - else fprintf(ficgp," %%*lf (%%*lf)"); - } - if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i); - else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1); - fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased); - for (j=1; j<= nlstate+1 ; j ++) { - if (j==i) fprintf(ficgp," %%lf (%%lf)"); - else fprintf(ficgp," %%*lf (%%*lf)"); - } - fprintf(ficgp,"\" t\"\" w l lt 0,"); - fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased); - for (j=1; j<= nlstate+1 ; j ++) { - if (j==i) fprintf(ficgp," %%lf (%%lf)"); - else fprintf(ficgp," %%*lf (%%*lf)"); - } - if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0"); - else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n"); - } /* state */ - } /* vpopbased */ - fprintf(ficgp,"\nset out;set out \"%s_%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1); /* Buggy gnuplot */ + fprintf(ficgp,"\nset out \"%s_%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1); + for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/ + if(vpopbased==0) + fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage); + else + fprintf(ficgp,"\nreplot "); + for (i=1; i<= nlstate+1 ; i ++) { + k=2*i; + fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1, vpopbased); + for (j=1; j<= nlstate+1 ; j ++) { + if (j==i) fprintf(ficgp," %%lf (%%lf)"); + else fprintf(ficgp," %%*lf (%%*lf)"); + } + if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i); + else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1); + fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased); + for (j=1; j<= nlstate+1 ; j ++) { + if (j==i) fprintf(ficgp," %%lf (%%lf)"); + else fprintf(ficgp," %%*lf (%%*lf)"); + } + fprintf(ficgp,"\" t\"\" w l lt 0,"); + fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased); + for (j=1; j<= nlstate+1 ; j ++) { + if (j==i) fprintf(ficgp," %%lf (%%lf)"); + else fprintf(ficgp," %%*lf (%%*lf)"); + } + if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0"); + else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n"); + } /* state */ + } /* vpopbased */ + fprintf(ficgp,"\nset out;set out \"%s_%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1); /* Buggy gnuplot */ } /* k1 */ @@ -5871,19 +6077,19 @@ plot [%.f:%.f] \"%s\" every :::%d::%d u for (cpt=1; cpt<= nlstate ; cpt ++) { fprintf(ficgp,"\n# 3d: Life expectancy with EXP_ files: cov=%d state=%d",k1, cpt); - for (k=1; k<=cptcoveff; k++){ /* For each covariate and each value */ - lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */ - /* decodtabm(1,1,4) = 1 because h=1 k= (1) 1 1 1 */ - /* decodtabm(1,2,4) = 1 because h=1 k= 1 (1) 1 1 */ - /* decodtabm(13,3,4)= 2 because h=13 k= 1 1 (2) 2 */ - vlv= nbcode[Tvaraff[k]][lv]; - fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv); + for (k=1; k<=nqveff; k++){ /* For each covariate and each value */ + lv= decodtabm(k1,k,nqveff); /* Should be the covariate number corresponding to k1 combination */ + /* decodtabm(1,1,4) = 1 because h=1 k= (1) 1 1 1 */ + /* decodtabm(1,2,4) = 1 because h=1 k= 1 (1) 1 1 */ + /* decodtabm(13,3,4)= 2 because h=13 k= 1 1 (2) 2 */ + vlv= nbcode[Tvaraff[k]][lv]; + fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv); } fprintf(ficgp,"\n#\n"); - if(invalidvarcomb[k1]){ - fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); - continue; - } + if(invalidvarcomb[k1]){ + fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); + continue; + } /* k=2+nlstate*(2*cpt-2); */ k=2+(nlstate+1)*(cpt-1); @@ -5891,41 +6097,41 @@ plot [%.f:%.f] \"%s\" every :::%d::%d u fprintf(ficgp,"set ter svg size 640, 480\n\ plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),k1-1,k1-1,k,cpt); /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1); - for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) "); - fprintf(ficgp,"\" t \"e%d1\" w l",cpt); - fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1); - for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) "); - fprintf(ficgp,"\" t \"e%d1\" w l",cpt); + for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) "); + fprintf(ficgp,"\" t \"e%d1\" w l",cpt); + fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1); + for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) "); + fprintf(ficgp,"\" t \"e%d1\" w l",cpt); */ for (i=1; i< nlstate ; i ++) { - fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+i,cpt,i+1); - /* fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/ + fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+i,cpt,i+1); + /* fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/ } fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+nlstate,cpt); } } - /* 4eme */ + /* 4eme */ /* Survival functions (period) from state i in state j by initial state i */ for (k1=1; k1<= m ; k1 ++) { /* For each multivariate if any */ for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */ fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt); - for (k=1; k<=cptcoveff; k++){ /* For each covariate and each value */ - lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */ - /* decodtabm(1,1,4) = 1 because h=1 k= (1) 1 1 1 */ - /* decodtabm(1,2,4) = 1 because h=1 k= 1 (1) 1 1 */ - /* decodtabm(13,3,4)= 2 because h=13 k= 1 1 (2) 2 */ - vlv= nbcode[Tvaraff[k]][lv]; - fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv); + for (k=1; k<=nqveff; k++){ /* For each covariate and each value */ + lv= decodtabm(k1,k,nqveff); /* Should be the covariate number corresponding to k1 combination */ + /* decodtabm(1,1,4) = 1 because h=1 k= (1) 1 1 1 */ + /* decodtabm(1,2,4) = 1 because h=1 k= 1 (1) 1 1 */ + /* decodtabm(13,3,4)= 2 because h=13 k= 1 1 (2) 2 */ + vlv= nbcode[Tvaraff[k]][lv]; + fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv); } fprintf(ficgp,"\n#\n"); - if(invalidvarcomb[k1]){ - fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); - continue; - } + if(invalidvarcomb[k1]){ + fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); + continue; + } fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1); fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\ @@ -5934,16 +6140,16 @@ unset log y\n plot [%.f:%.f] ", ageminpar, agemaxpar); k=3; for (i=1; i<= nlstate ; i ++){ - if(i==1){ - fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_")); - }else{ - fprintf(ficgp,", '' "); - } - l=(nlstate+ndeath)*(i-1)+1; - fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); - for (j=2; j<= nlstate+ndeath ; j ++) - fprintf(ficgp,"+$%d",k+l+j-1); - fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt); + if(i==1){ + fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_")); + }else{ + fprintf(ficgp,", '' "); + } + l=(nlstate+ndeath)*(i-1)+1; + fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); + for (j=2; j<= nlstate+ndeath ; j ++) + fprintf(ficgp,"+$%d",k+l+j-1); + fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt); } /* nlstate */ fprintf(ficgp,"\nset out\n"); } /* end cpt state*/ @@ -5953,10 +6159,10 @@ plot [%.f:%.f] ", ageminpar, agemaxpar) /* Survival functions (period) from state i in state j by final state j */ for (k1=1; k1<= m ; k1 ++) { /* For each covariate if any */ for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state */ - + fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt); - for (k=1; k<=cptcoveff; k++){ /* For each covariate and each value */ - lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */ + for (k=1; k<=nqveff; k++){ /* For each covariate and each value */ + lv= decodtabm(k1,k,nqveff); /* Should be the covariate number corresponding to k1 combination */ /* decodtabm(1,1,4) = 1 because h=1 k= (1) 1 1 1 */ /* decodtabm(1,2,4) = 1 because h=1 k= 1 (1) 1 1 */ /* decodtabm(13,3,4)= 2 because h=13 k= 1 1 (2) 2 */ @@ -5964,10 +6170,10 @@ plot [%.f:%.f] ", ageminpar, agemaxpar) fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv); } fprintf(ficgp,"\n#\n"); - if(invalidvarcomb[k1]){ - fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); - continue; - } + if(invalidvarcomb[k1]){ + fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); + continue; + } fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1); fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\ @@ -6003,10 +6209,10 @@ plot [%.f:%.f] ", ageminpar, agemaxpar) /* CV preval stable (period) for each covariate */ for (k1=1; k1<= m ; k1 ++) { /* For each covariate combination (1 to m=2**k), if any covariate is present */ for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */ - + fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt); - for (k=1; k<=cptcoveff; k++){ /* For each covariate and each value */ - lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */ + for (k=1; k<=nqveff; k++){ /* For each covariate and each value */ + lv= decodtabm(k1,k,nqveff); /* Should be the covariate number corresponding to k1 combination */ /* decodtabm(1,1,4) = 1 because h=1 k= (1) 1 1 1 */ /* decodtabm(1,2,4) = 1 because h=1 k= 1 (1) 1 1 */ /* decodtabm(13,3,4)= 2 because h=13 k= 1 1 (2) 2 */ @@ -6014,15 +6220,15 @@ plot [%.f:%.f] ", ageminpar, agemaxpar) fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv); } fprintf(ficgp,"\n#\n"); - if(invalidvarcomb[k1]){ - fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); - continue; - } - + if(invalidvarcomb[k1]){ + fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); + continue; + } + fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1); fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\ -set ter svg size 640, 480\n\ -unset log y\n\ +set ter svg size 640, 480\n \ +unset log y\n \ plot [%.f:%.f] ", ageminpar, agemaxpar); k=3; /* Offset */ for (i=1; i<= nlstate ; i ++){ @@ -6039,26 +6245,26 @@ plot [%.f:%.f] ", ageminpar, agemaxpar) fprintf(ficgp,"\nset out\n"); } /* end cpt state*/ } /* end covariate */ - - + + /* 7eme */ if(backcast == 1){ /* CV back preval stable (period) for each covariate */ for (k1=1; k1<= m ; k1 ++) { /* For each covariate combination (1 to m=2**k), if any covariate is present */ for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */ fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt); - for (k=1; k<=cptcoveff; k++){ /* For each covariate and each value */ - lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */ + for (k=1; k<=nqveff; k++){ /* For each covariate and each value */ + lv= decodtabm(k1,k,nqveff); /* Should be the covariate number corresponding to k1 combination */ /* decodtabm(1,1,4) = 1 because h=1 k= (1) 1 1 1 */ /* decodtabm(1,2,4) = 1 because h=1 k= 1 (1) 1 1 */ - /* decodtabm(13,3,4)= 2 because h=13 k= 1 1 (2) 2 */ + /* decodtabm(13,3,4)= 2 because h=13 k= 1 1 (2) 2 */ vlv= nbcode[Tvaraff[k]][lv]; fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv); } fprintf(ficgp,"\n#\n"); if(invalidvarcomb[k1]){ - fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); - continue; + fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); + continue; } fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1); @@ -6087,15 +6293,15 @@ plot [%.f:%.f] ", ageminpar, agemaxpar) } /* end covariate */ } /* End if backcast */ - /* 8eme */ + /* 8eme */ if(prevfcast==1){ /* Projection from cross-sectional to stable (period) for each covariate */ for (k1=1; k1<= m ; k1 ++) { /* For each covariate combination (1 to m=2**k), if any covariate is present */ for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */ fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt); - for (k=1; k<=cptcoveff; k++){ /* For each correspondig covariate value */ - lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */ + for (k=1; k<=nqveff; k++){ /* For each correspondig covariate value */ + lv= decodtabm(k1,k,nqveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */ /* decodtabm(1,1,4) = 1 because h=1 k= (1) 1 1 1 */ /* decodtabm(1,2,4) = 1 because h=1 k= 1 (1) 1 1 */ /* decodtabm(13,3,4)= 2 because h=13 k= 1 1 (2) 2 */ @@ -6104,15 +6310,15 @@ plot [%.f:%.f] ", ageminpar, agemaxpar) } fprintf(ficgp,"\n#\n"); if(invalidvarcomb[k1]){ - fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); - continue; + fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); + continue; } fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n "); fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1); fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\ -set ter svg size 640, 480\n \ -unset log y\n \ +set ter svg size 640, 480\n \ +unset log y\n \ plot [%.f:%.f] ", ageminpar, agemaxpar); for (i=1; i<= nlstate+1 ; i ++){ /* nlstate +1 p11 p21 p.1 */ /*# V1 = 1 V2 = 0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/ @@ -6124,7 +6330,7 @@ plot [%.f:%.f] ", ageminpar, agemaxpar) }else{ fprintf(ficgp,",\\\n '' "); } - if(cptcoveff ==0){ /* No covariate */ + if(nqveff ==0){ /* No covariate */ ioffset=2; /* Age is in 2 */ /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/ /*# 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 */ @@ -6138,18 +6344,18 @@ plot [%.f:%.f] ", ageminpar, agemaxpar) fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ", \ ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt ); }else{ /* more than 2 covariates */ - if(cptcoveff ==1){ + if(nqveff ==1){ ioffset=4; /* Age is in 4 */ }else{ ioffset=6; /* Age is in 6 */ - /*# V1 = 1 V2 = 0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/ - /*# 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 */ + /*# V1 = 1 V2 = 0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/ + /*# 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 */ } fprintf(ficgp," u %d:(",ioffset); kl=0; strcpy(gplotcondition,"("); - for (k=1; k<=cptcoveff; k++){ /* For each covariate writing the chain of conditions */ - lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */ + for (k=1; k<=nqveff; k++){ /* For each covariate writing the chain of conditions */ + lv= decodtabm(k1,k,nqveff); /* Should be the covariate value corresponding to combination k1 and covariate k */ /* decodtabm(1,1,4) = 1 because h=1 k= (1) 1 1 1 */ /* decodtabm(1,2,4) = 1 because h=1 k= 1 (1) 1 1 */ /* decodtabm(13,3,4)= 2 because h=13 k= 1 1 (2) 2 */ @@ -6157,7 +6363,7 @@ plot [%.f:%.f] ", ageminpar, agemaxpar) kl++; sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]); kl++; - if(k 1) + if(k 1) sprintf(gplotcondition+strlen(gplotcondition)," && "); } strcpy(gplotcondition+strlen(gplotcondition),")"); @@ -6169,34 +6375,34 @@ plot [%.f:%.f] ", ageminpar, agemaxpar) fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p.%d' with line ", gplotcondition, \ ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt ); }else{ - fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ - ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt ); + fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ + ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt ); } } /* end if covariate */ } /* nlstate */ fprintf(ficgp,"\nset out\n"); - } /* end cpt state*/ - } /* end covariate */ - } /* End if prevfcast */ + } /* end cpt state*/ + } /* end covariate */ + } /* End if prevfcast */ - /* proba elementaires */ - fprintf(ficgp,"\n##############\n#MLE estimated parameters\n#############\n"); + /* proba elementaires */ + fprintf(ficgp,"\n##############\n#MLE estimated parameters\n#############\n"); for(i=1,jk=1; i <=nlstate; i++){ fprintf(ficgp,"# initial state %d\n",i); for(k=1; k <=(nlstate+ndeath); k++){ if (k != i) { - fprintf(ficgp,"# current state %d\n",k); - for(j=1; j <=ncovmodel; j++){ - fprintf(ficgp,"p%d=%f; ",jk,p[jk]); - jk++; - } - fprintf(ficgp,"\n"); + fprintf(ficgp,"# current state %d\n",k); + for(j=1; j <=ncovmodel; j++){ + fprintf(ficgp,"p%d=%f; ",jk,p[jk]); + jk++; + } + fprintf(ficgp,"\n"); } } - } + } fprintf(ficgp,"##############\n#\n"); - + /*goto avoid;*/ fprintf(ficgp,"\n##############\n#Graphics of probabilities or incidences\n#############\n"); fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n"); @@ -6212,268 +6418,273 @@ plot [%.f:%.f] ", ageminpar, agemaxpar) fprintf(ficgp,"# +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n"); fprintf(ficgp,"# +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n"); fprintf(ficgp,"#\n"); - for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/ - fprintf(ficgp,"# ng=%d\n",ng); - fprintf(ficgp,"# jk=1 to 2^%d=%d\n",cptcoveff,m); - for(jk=1; jk <=m; jk++) { - fprintf(ficgp,"# jk=%d\n",jk); - fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng); - fprintf(ficgp,"\nset ter svg size 640, 480 "); - if (ng==1){ - fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */ - fprintf(ficgp,"\nunset log y"); - }else if (ng==2){ - fprintf(ficgp,"\nset ylabel \"Probability\"\n"); - fprintf(ficgp,"\nset log y"); - }else if (ng==3){ - fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n"); - fprintf(ficgp,"\nset log y"); - }else - fprintf(ficgp,"\nunset title "); - fprintf(ficgp,"\nplot [%.f:%.f] ",ageminpar,agemaxpar); - i=1; - for(k2=1; k2<=nlstate; k2++) { - k3=i; - for(k=1; k<=(nlstate+ndeath); k++) { - if (k != k2){ - switch( ng) { - case 1: - if(nagesqr==0) - fprintf(ficgp," p%d+p%d*x",i,i+1); - else /* nagesqr =1 */ - fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr); - break; - case 2: /* ng=2 */ - if(nagesqr==0) - fprintf(ficgp," exp(p%d+p%d*x",i,i+1); - else /* nagesqr =1 */ - fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr); - break; - case 3: - if(nagesqr==0) - fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1); - else /* nagesqr =1 */ - fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr); - break; - } - ij=1;/* To be checked else nbcode[0][0] wrong */ - for(j=3; j <=ncovmodel-nagesqr; j++) { - /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */ - if(ij <=cptcovage) { /* Bug valgrind */ - if((j-2)==Tage[ij]) { /* Bug valgrind */ - fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,j-2)]); - /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */ - ij++; - } - } - else - fprintf(ficgp,"+p%d*%d",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,j-2)]); - } - }else{ - i=i-ncovmodel; - if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */ - fprintf(ficgp," (1."); - } + for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/ + fprintf(ficgp,"# ng=%d\n",ng); + fprintf(ficgp,"# jk=1 to 2^%d=%d\n",nqveff,m); + for(jk=1; jk <=m; jk++) { + fprintf(ficgp,"# jk=%d\n",jk); + fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng); + fprintf(ficgp,"\nset ter svg size 640, 480 "); + if (ng==1){ + fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */ + fprintf(ficgp,"\nunset log y"); + }else if (ng==2){ + fprintf(ficgp,"\nset ylabel \"Probability\"\n"); + fprintf(ficgp,"\nset log y"); + }else if (ng==3){ + fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n"); + fprintf(ficgp,"\nset log y"); + }else + fprintf(ficgp,"\nunset title "); + fprintf(ficgp,"\nplot [%.f:%.f] ",ageminpar,agemaxpar); + i=1; + for(k2=1; k2<=nlstate; k2++) { + k3=i; + for(k=1; k<=(nlstate+ndeath); k++) { + if (k != k2){ + switch( ng) { + case 1: + if(nagesqr==0) + fprintf(ficgp," p%d+p%d*x",i,i+1); + else /* nagesqr =1 */ + fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr); + break; + case 2: /* ng=2 */ + if(nagesqr==0) + fprintf(ficgp," exp(p%d+p%d*x",i,i+1); + else /* nagesqr =1 */ + fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr); + break; + case 3: + if(nagesqr==0) + fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1); + else /* nagesqr =1 */ + fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr); + break; + } + ij=1;/* To be checked else nbcode[0][0] wrong */ + for(j=3; j <=ncovmodel-nagesqr; j++) { + /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */ + if(ij <=cptcovage) { /* Bug valgrind */ + if((j-2)==Tage[ij]) { /* Bug valgrind */ + fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,j-2)]); + /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */ + ij++; + } + } + else + fprintf(ficgp,"+p%d*%d",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,j-2)]); + } + }else{ + i=i-ncovmodel; + if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */ + fprintf(ficgp," (1."); + } - if(ng != 1){ - fprintf(ficgp,")/(1"); + if(ng != 1){ + fprintf(ficgp,")/(1"); - for(k1=1; k1 <=nlstate; k1++){ - if(nagesqr==0) - fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1); - else /* nagesqr =1 */ - fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1,k3+(k1-1)*ncovmodel+1+nagesqr); + for(k1=1; k1 <=nlstate; k1++){ + if(nagesqr==0) + fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1); + else /* nagesqr =1 */ + fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1,k3+(k1-1)*ncovmodel+1+nagesqr); - ij=1; - for(j=3; j <=ncovmodel-nagesqr; j++){ - if(ij <=cptcovage) { /* Bug valgrind */ - if((j-2)==Tage[ij]) { /* Bug valgrind */ - fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]); - /* fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */ - ij++; - } - } - else - fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]); - } - fprintf(ficgp,")"); - } - fprintf(ficgp,")"); - if(ng ==2) - fprintf(ficgp," t \"p%d%d\" ", k2,k); - else /* ng= 3 */ - fprintf(ficgp," t \"i%d%d\" ", k2,k); - }else{ /* end ng <> 1 */ - if( k !=k2) /* logit p11 is hard to draw */ - fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k); - } - if ((k+k2)!= (nlstate*2+ndeath) && ng != 1) - fprintf(ficgp,","); - if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath)) - fprintf(ficgp,","); - i=i+ncovmodel; - } /* end k */ - } /* end k2 */ - fprintf(ficgp,"\n set out\n"); - } /* end jk */ - } /* end ng */ - /* avoid: */ - fflush(ficgp); + ij=1; + for(j=3; j <=ncovmodel-nagesqr; j++){ + if(ij <=cptcovage) { /* Bug valgrind */ + if((j-2)==Tage[ij]) { /* Bug valgrind */ + fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]); + /* fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */ + ij++; + } + } + else + fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]); + } + fprintf(ficgp,")"); + } + fprintf(ficgp,")"); + if(ng ==2) + fprintf(ficgp," t \"p%d%d\" ", k2,k); + else /* ng= 3 */ + fprintf(ficgp," t \"i%d%d\" ", k2,k); + }else{ /* end ng <> 1 */ + if( k !=k2) /* logit p11 is hard to draw */ + fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k); + } + if ((k+k2)!= (nlstate*2+ndeath) && ng != 1) + fprintf(ficgp,","); + if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath)) + fprintf(ficgp,","); + i=i+ncovmodel; + } /* end k */ + } /* end k2 */ + fprintf(ficgp,"\n set out\n"); + } /* end jk */ + } /* end ng */ + /* avoid: */ + fflush(ficgp); } /* end gnuplot */ /*************** Moving average **************/ /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */ -int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){ + int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){ - int i, cpt, cptcod; - int modcovmax =1; - int mobilavrange, mob; - int iage=0; - - double sum=0.; - double age; - double *sumnewp, *sumnewm; - double *agemingood, *agemaxgood; /* Currently identical for all covariates */ - - - /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose */ - /* a covariate has 2 modalities, should be equal to ncovcombmax *\/ */ - - sumnewp = vector(1,ncovcombmax); - sumnewm = vector(1,ncovcombmax); - agemingood = vector(1,ncovcombmax); - agemaxgood = vector(1,ncovcombmax); - - for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ - sumnewm[cptcod]=0.; - sumnewp[cptcod]=0.; - agemingood[cptcod]=0; - agemaxgood[cptcod]=0; - } - if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */ + int i, cpt, cptcod; + int modcovmax =1; + int mobilavrange, mob; + int iage=0; + + double sum=0.; + double age; + double *sumnewp, *sumnewm; + double *agemingood, *agemaxgood; /* Currently identical for all covariates */ + + + /* modcovmax=2*nqveff;/\* Max number of modalities. We suppose */ + /* a covariate has 2 modalities, should be equal to ncovcombmax *\/ */ + + sumnewp = vector(1,ncovcombmax); + sumnewm = vector(1,ncovcombmax); + agemingood = vector(1,ncovcombmax); + agemaxgood = vector(1,ncovcombmax); + + for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ + sumnewm[cptcod]=0.; + sumnewp[cptcod]=0.; + agemingood[cptcod]=0; + agemaxgood[cptcod]=0; + } + if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */ - if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){ - if(mobilav==1) mobilavrange=5; /* default */ - else mobilavrange=mobilav; - for (age=bage; age<=fage; age++) - for (i=1; i<=nlstate;i++) - for (cptcod=1;cptcod<=ncovcombmax;cptcod++) - mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod]; - /* We keep the original values on the extreme ages bage, fage and for - fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2 - we use a 5 terms etc. until the borders are no more concerned. - */ - for (mob=3;mob <=mobilavrange;mob=mob+2){ - for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ - for (i=1; i<=nlstate;i++){ - for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ - mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod]; - for (cpt=1;cpt<=(mob-1)/2;cpt++){ - mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod]; - mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod]; - } - mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob; - } - } - }/* end age */ - }/* end mob */ - }else - return -1; - for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ - /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */ - agemingood[cptcod]=fage-(mob-1)/2; - for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, finding the youngest wrong */ - sumnewm[cptcod]=0.; - for (i=1; i<=nlstate;i++){ - sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod]; - } - if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */ - agemingood[cptcod]=age; - }else{ /* bad */ - for (i=1; i<=nlstate;i++){ - mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; - } /* i */ - } /* end bad */ - }/* age */ - sum=0.; - for (i=1; i<=nlstate;i++){ - sum+=mobaverage[(int)agemingood[cptcod]][i][cptcod]; - } - if(fabs(sum - 1.) > 1.e-3) { /* bad */ - printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any descending age!\n",cptcod); - /* for (i=1; i<=nlstate;i++){ */ - /* mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */ - /* } /\* i *\/ */ - } /* end bad */ - /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */ - /* From youngest, finding the oldest wrong */ - agemaxgood[cptcod]=bage+(mob-1)/2; - for (age=bage+(mob-1)/2; age<=fage; age++){ - sumnewm[cptcod]=0.; - for (i=1; i<=nlstate;i++){ - sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod]; - } - if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */ - agemaxgood[cptcod]=age; - }else{ /* bad */ - for (i=1; i<=nlstate;i++){ - mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; - } /* i */ - } /* end bad */ - }/* age */ - sum=0.; - for (i=1; i<=nlstate;i++){ - sum+=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; - } - if(fabs(sum - 1.) > 1.e-3) { /* bad */ - printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any ascending age!\n",cptcod); - /* for (i=1; i<=nlstate;i++){ */ - /* mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */ - /* } /\* i *\/ */ - } /* end bad */ - - for (age=bage; age<=fage; age++){ - printf("%d %d ", cptcod, (int)age); - sumnewp[cptcod]=0.; - sumnewm[cptcod]=0.; - for (i=1; i<=nlstate;i++){ - sumnewp[cptcod]+=probs[(int)age][i][cptcod]; - sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod]; - /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */ - } - /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */ - } - /* printf("\n"); */ - /* } */ - /* brutal averaging */ - for (i=1; i<=nlstate;i++){ - for (age=1; age<=bage; age++){ - mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; - /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */ - } - for (age=fage; age<=AGESUP; age++){ - mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; - /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */ - } - } /* end i status */ - for (i=nlstate+1; i<=nlstate+ndeath;i++){ - for (age=1; age<=AGESUP; age++){ - /*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*/ - mobaverage[(int)age][i][cptcod]=0.; - } - } - }/* end cptcod */ - free_vector(sumnewm,1, ncovcombmax); - free_vector(sumnewp,1, ncovcombmax); - free_vector(agemaxgood,1, ncovcombmax); - free_vector(agemingood,1, ncovcombmax); - return 0; -}/* End movingaverage */ + if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){ + if(mobilav==1) mobilavrange=5; /* default */ + else mobilavrange=mobilav; + for (age=bage; age<=fage; age++) + for (i=1; i<=nlstate;i++) + for (cptcod=1;cptcod<=ncovcombmax;cptcod++) + mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod]; + /* We keep the original values on the extreme ages bage, fage and for + fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2 + we use a 5 terms etc. until the borders are no more concerned. + */ + for (mob=3;mob <=mobilavrange;mob=mob+2){ + for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ + for (i=1; i<=nlstate;i++){ + for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ + mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod]; + for (cpt=1;cpt<=(mob-1)/2;cpt++){ + mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod]; + mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod]; + } + mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob; + } + } + }/* end age */ + }/* end mob */ + }else + return -1; + for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ + /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */ + if(invalidvarcomb[cptcod]){ + printf("\nCombination (%d) ignored because no cases \n",cptcod); + continue; + } + + agemingood[cptcod]=fage-(mob-1)/2; + for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, finding the youngest wrong */ + sumnewm[cptcod]=0.; + for (i=1; i<=nlstate;i++){ + sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod]; + } + if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */ + agemingood[cptcod]=age; + }else{ /* bad */ + for (i=1; i<=nlstate;i++){ + mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; + } /* i */ + } /* end bad */ + }/* age */ + sum=0.; + for (i=1; i<=nlstate;i++){ + sum+=mobaverage[(int)agemingood[cptcod]][i][cptcod]; + } + if(fabs(sum - 1.) > 1.e-3) { /* bad */ + printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any descending age!\n",cptcod); + /* for (i=1; i<=nlstate;i++){ */ + /* mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */ + /* } /\* i *\/ */ + } /* end bad */ + /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */ + /* From youngest, finding the oldest wrong */ + agemaxgood[cptcod]=bage+(mob-1)/2; + for (age=bage+(mob-1)/2; age<=fage; age++){ + sumnewm[cptcod]=0.; + for (i=1; i<=nlstate;i++){ + sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod]; + } + if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */ + agemaxgood[cptcod]=age; + }else{ /* bad */ + for (i=1; i<=nlstate;i++){ + mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; + } /* i */ + } /* end bad */ + }/* age */ + sum=0.; + for (i=1; i<=nlstate;i++){ + sum+=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; + } + if(fabs(sum - 1.) > 1.e-3) { /* bad */ + printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any ascending age!\n",cptcod); + /* for (i=1; i<=nlstate;i++){ */ + /* mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */ + /* } /\* i *\/ */ + } /* end bad */ + + for (age=bage; age<=fage; age++){ + printf("%d %d ", cptcod, (int)age); + sumnewp[cptcod]=0.; + sumnewm[cptcod]=0.; + for (i=1; i<=nlstate;i++){ + sumnewp[cptcod]+=probs[(int)age][i][cptcod]; + sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod]; + /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */ + } + /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */ + } + /* printf("\n"); */ + /* } */ + /* brutal averaging */ + for (i=1; i<=nlstate;i++){ + for (age=1; age<=bage; age++){ + mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; + /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */ + } + for (age=fage; age<=AGESUP; age++){ + mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; + /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */ + } + } /* end i status */ + for (i=nlstate+1; i<=nlstate+ndeath;i++){ + for (age=1; age<=AGESUP; age++){ + /*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*/ + mobaverage[(int)age][i][cptcod]=0.; + } + } + }/* end cptcod */ + free_vector(sumnewm,1, ncovcombmax); + free_vector(sumnewp,1, ncovcombmax); + free_vector(agemaxgood,1, ncovcombmax); + free_vector(agemingood,1, ncovcombmax); + return 0; + }/* End movingaverage */ /************** Forecasting ******************/ -void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){ +void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int nqveff){ /* proj1, year, month, day of starting projection agemin, agemax range of age dateprev1 dateprev2 range of dates during which prevalence is computed @@ -6504,7 +6715,7 @@ void prevforecast(char fileres[], double printf("Computing forecasting: result on file '%s', please wait... \n", fileresf); fprintf(ficlog,"Computing forecasting: result on file '%s', please wait... \n", fileresf); - if (cptcoveff==0) ncodemax[cptcoveff]=1; + if (nqveff==0) ncodemax[nqveff]=1; stepsize=(int) (stepm+YEARM-1)/YEARM; @@ -6525,7 +6736,7 @@ void prevforecast(char fileres[], double if(jprojmean==0) jprojmean=1; if(mprojmean==0) jprojmean=1; - i1=cptcoveff; + i1=nqveff; if (cptcovn < 1){i1=1;} fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); @@ -6534,10 +6745,10 @@ void prevforecast(char fileres[], double /* if (h==(int)(YEARM*yearp)){ */ for(cptcov=1, k=0;cptcov<=i1;cptcov++){ - for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ + for(cptcod=1;cptcod<=ncodemax[nqveff];cptcod++){ k=k+1; fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#"); - for(j=1;j<=cptcoveff;j++) { + for(j=1;j<=nqveff;j++) { fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); } fprintf(ficresf," yearproj age"); @@ -6559,7 +6770,7 @@ void prevforecast(char fileres[], double for (h=0; h<=nhstepm; h++){ if (h*hstepm/YEARM*stepm ==yearp) { fprintf(ficresf,"\n"); - for(j=1;j<=cptcoveff;j++) + for(j=1;j<=nqveff;j++) fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm); } @@ -6593,7 +6804,7 @@ void prevforecast(char fileres[], double } /* /\************** Back Forecasting ******************\/ */ -/* void prevbackforecast(char fileres[], double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */ +/* void prevbackforecast(char fileres[], double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int nqveff){ */ /* /\* back1, year, month, day of starting backection */ /* agemin, agemax range of age */ /* dateprev1 dateprev2 range of dates during which prevalence is computed */ @@ -6625,7 +6836,7 @@ void prevforecast(char fileres[], double /* printf("Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */ /* fprintf(ficlog,"Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */ -/* if (cptcoveff==0) ncodemax[cptcoveff]=1; */ +/* if (nqveff==0) ncodemax[nqveff]=1; */ /* /\* if (mobilav!=0) { *\/ */ /* /\* mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */ @@ -6653,7 +6864,7 @@ void prevforecast(char fileres[], double /* if(jprojmean==0) jprojmean=1; */ /* if(mprojmean==0) jprojmean=1; */ -/* i1=cptcoveff; */ +/* i1=nqveff; */ /* if (cptcovn < 1){i1=1;} */ /* fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); */ @@ -6662,10 +6873,10 @@ void prevforecast(char fileres[], double /* /\* if (h==(int)(YEARM*yearp)){ *\/ */ /* for(cptcov=1, k=0;cptcov<=i1;cptcov++){ */ -/* for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */ +/* for(cptcod=1;cptcod<=ncodemax[nqveff];cptcod++){ */ /* k=k+1; */ /* fprintf(ficresfb,"\n#****** hbijx=probability over h years, hp.jx is weighted by observed prev \n#"); */ -/* for(j=1;j<=cptcoveff;j++) { */ +/* for(j=1;j<=nqveff;j++) { */ /* fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* } */ /* fprintf(ficresfb," yearbproj age"); */ @@ -6687,7 +6898,7 @@ void prevforecast(char fileres[], double /* for (h=0; h<=nhstepm; h++){ */ /* if (h*hstepm/YEARM*stepm ==yearp) { */ /* fprintf(ficresfb,"\n"); */ -/* for(j=1;j<=cptcoveff;j++) */ +/* for(j=1;j<=nqveff;j++) */ /* fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec+h*hstepm/YEARM*stepm); */ /* } */ @@ -6750,7 +6961,7 @@ void populforecast(char fileres[], doubl printf("Computing forecasting: result on file '%s' \n", filerespop); fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); - if (cptcoveff==0) ncodemax[cptcoveff]=1; + if (nqveff==0) ncodemax[nqveff]=1; /* if (mobilav!=0) { */ /* mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */ @@ -6785,10 +6996,10 @@ void populforecast(char fileres[], doubl } for(cptcov=1,k=0;cptcov<=i2;cptcov++){ - for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ + for(cptcod=1;cptcod<=ncodemax[nqveff];cptcod++){ k=k+1; fprintf(ficrespop,"\n#******"); - for(j=1;j<=cptcoveff;j++) { + for(j=1;j<=nqveff;j++) { fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); } fprintf(ficrespop,"******\n"); @@ -7148,12 +7359,13 @@ int readdata(char datafile[], int firsto /*-------- data file ----------*/ FILE *fic; char dummy[]=" "; - int i=0, j=0, n=0; + int i=0, j=0, n=0, iv=0; + int lstra; int linei, month, year,iout; char line[MAXLINE], linetmp[MAXLINE]; char stra[MAXLINE], strb[MAXLINE]; char *stratrunc; - int lstra; + if((fic=fopen(datafile,"r"))==NULL) { @@ -7180,41 +7392,106 @@ int readdata(char datafile[], int firsto } trimbb(linetmp,line); /* Trims multiple blanks in line */ strcpy(line, linetmp); - - + + /* Loops on waves */ for (j=maxwav;j>=1;j--){ + for (iv=nqtv;iv>=1;iv--){ /* Loop on time varying quantitative variables */ + cutv(stra, strb, line, ' '); + if(strb[0]=='.') { /* Missing value */ + lval=-1; + }else{ + errno=0; + /* what_kind_of_number(strb); */ + dval=strtod(strb,&endptr); + /* if( strb[0]=='\0' || (*endptr != '\0')){ */ + /* if(strb != endptr && *endptr == '\0') */ + /* dval=dlval; */ + /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */ + if( strb[0]=='\0' || (*endptr != '\0')){ + printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong. Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav); + fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong. Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog); + return 1; + } + cotqvar[j][iv][i]=dval; + } + strcpy(line,stra); + }/* end loop ntqv */ + + for (iv=ntv;iv>=1;iv--){ /* Loop on time varying dummies */ + cutv(stra, strb, line, ' '); + if(strb[0]=='.') { /* Missing value */ + lval=-1; + }else{ + errno=0; + lval=strtol(strb,&endptr,10); + /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/ + if( strb[0]=='\0' || (*endptr != '\0')){ + printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong. Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav); + fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong. Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog); + return 1; + } + } + if(lval <-1 || lval >1){ + printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \ + Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \ + for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \ + For example, for multinomial values like 1, 2 and 3,\n \ + build V1=0 V2=0 for the reference value (1),\n \ + V1=1 V2=0 for (2) \n \ + and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \ + output of IMaCh is often meaningless.\n \ + Exiting.\n",lval,linei, i,line,j); + fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \ + Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \ + for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \ + For example, for multinomial values like 1, 2 and 3,\n \ + build V1=0 V2=0 for the reference value (1),\n \ + V1=1 V2=0 for (2) \n \ + and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \ + output of IMaCh is often meaningless.\n \ + Exiting.\n",lval,linei, i,line,j);fflush(ficlog); + return 1; + } + cotvar[j][iv][i]=(double)(lval); + strcpy(line,stra); + }/* end loop ntv */ + + /* Statuses at wave */ cutv(stra, strb, line, ' '); - if(strb[0]=='.') { /* Missing status */ - lval=-1; + if(strb[0]=='.') { /* Missing value */ + lval=-1; }else{ - errno=0; - lval=strtol(strb,&endptr,10); - /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/ - if( strb[0]=='\0' || (*endptr != '\0')){ - printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong. Exiting.\n", strb, linei,i,line,j,maxwav); - fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong. Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog); - return 1; - } + errno=0; + lval=strtol(strb,&endptr,10); + /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/ + if( strb[0]=='\0' || (*endptr != '\0')){ + printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong. Exiting.\n", strb, linei,i,line,j,maxwav); + fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong. Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog); + return 1; + } } + s[j][i]=lval; - + + /* Date of Interview */ strcpy(line,stra); cutv(stra, strb,line,' '); if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){ } else if( (iout=sscanf(strb,"%s.",dummy)) != 0){ - month=99; - year=9999; + month=99; + year=9999; }else{ - printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d. Exiting.\n",strb, linei,i, line,j); - fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d. Exiting.\n",strb, linei,i, line,j);fflush(ficlog); - return 1; + printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d. Exiting.\n",strb, linei,i, line,j); + fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d. Exiting.\n",strb, linei,i, line,j);fflush(ficlog); + return 1; } anint[j][i]= (double) year; mint[j][i]= (double)month; strcpy(line,stra); - } /* ENd Waves */ - + } /* End loop on waves */ + + /* Date of death */ cutv(stra, strb,line,' '); if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){ } @@ -7223,13 +7500,14 @@ int readdata(char datafile[], int firsto year=9999; }else{ printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .). Exiting.\n",strb, linei,i,line); - fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .). Exiting.\n",strb, linei,i,line);fflush(ficlog); - return 1; + fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .). Exiting.\n",strb, linei,i,line);fflush(ficlog); + return 1; } andc[i]=(double) year; moisdc[i]=(double) month; strcpy(line,stra); + /* Date of birth */ cutv(stra, strb,line,' '); if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){ } @@ -7239,18 +7517,19 @@ int readdata(char datafile[], int firsto }else{ printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .). Exiting.\n",strb, linei,i,line); fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .). Exiting.\n",strb, linei,i,line);fflush(ficlog); - return 1; + return 1; } if (year==9999) { printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line); fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog); - return 1; + return 1; } annais[i]=(double)(year); moisnais[i]=(double)(month); strcpy(line,stra); - + + /* Sample weight */ cutv(stra, strb,line,' '); errno=0; dval=strtod(strb,&endptr); @@ -7262,22 +7541,44 @@ int readdata(char datafile[], int firsto } weight[i]=dval; strcpy(line,stra); + + for (iv=nqv;iv>=1;iv--){ /* Loop on fixed quantitative variables */ + cutv(stra, strb, line, ' '); + if(strb[0]=='.') { /* Missing value */ + lval=-1; + }else{ + errno=0; + /* what_kind_of_number(strb); */ + dval=strtod(strb,&endptr); + /* if(strb != endptr && *endptr == '\0') */ + /* dval=dlval; */ + /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */ + if( strb[0]=='\0' || (*endptr != '\0')){ + printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong. Exiting.\n", strb, linei,i,line, iv, nqv, maxwav); + fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong. Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog); + return 1; + } + coqvar[iv][i]=dval; + } + strcpy(line,stra); + }/* end loop nqv */ + /* Covariate values */ for (j=ncovcol;j>=1;j--){ cutv(stra, strb,line,' '); - if(strb[0]=='.') { /* Missing status */ - lval=-1; + if(strb[0]=='.') { /* Missing covariate value */ + lval=-1; }else{ - errno=0; - lval=strtol(strb,&endptr,10); - if( strb[0]=='\0' || (*endptr != '\0')){ - printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative). Exiting.\n",lval, linei,i, line); - fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative). Exiting.\n",lval, linei,i, line);fflush(ficlog); - return 1; - } + errno=0; + lval=strtol(strb,&endptr,10); + if( strb[0]=='\0' || (*endptr != '\0')){ + printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative). Exiting.\n",lval, linei,i, line); + fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative). Exiting.\n",lval, linei,i, line);fflush(ficlog); + return 1; + } } if(lval <-1 || lval >1){ - printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \ + printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \ Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \ for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \ For example, for multinomial values like 1, 2 and 3,\n \ @@ -7286,7 +7587,7 @@ int readdata(char datafile[], int firsto and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \ output of IMaCh is often meaningless.\n \ Exiting.\n",lval,linei, i,line,j); - fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \ + fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \ Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \ for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \ For example, for multinomial values like 1, 2 and 3,\n \ @@ -7295,7 +7596,7 @@ int readdata(char datafile[], int firsto and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \ output of IMaCh is often meaningless.\n \ Exiting.\n",lval,linei, i,line,j);fflush(ficlog); - return 1; + return 1; } covar[j][i]=(double)(lval); strcpy(line,stra); @@ -7319,13 +7620,11 @@ int readdata(char datafile[], int firsto return (0); /* endread: */ - printf("Exiting readdata: "); - fclose(fic); - return (1); - - - + printf("Exiting readdata: "); + fclose(fic); + return (1); } + void removespace(char *str) { char *p1 = str, *p2 = str; do @@ -7334,20 +7633,21 @@ void removespace(char *str) { while (*p1++ == *p2++); } -int decodemodel ( char model[], int lastobs) /**< This routine decode the model and returns: - * Model V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age - * - nagesqr = 1 if age*age in the model, otherwise 0. - * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age - * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age - * - cptcovage number of covariates with age*products =2 - * - cptcovs number of simple covariates - * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10 - * which is a new column after the 9 (ncovcol) variables. - * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual - * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage - * Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6. - * - Tvard[k] p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 . - */ +int decodemodel ( char model[], int lastobs) + /**< This routine decode the model and returns: + * Model V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age + * - nagesqr = 1 if age*age in the model, otherwise 0. + * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age + * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age + * - cptcovage number of covariates with age*products =2 + * - cptcovs number of simple covariates + * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10 + * which is a new column after the 9 (ncovcol) variables. + * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual + * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage + * Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6. + * - Tvard[k] p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 . + */ { int i, j, k, ks; int j1, k1, k2; @@ -7372,34 +7672,34 @@ int decodemodel ( char model[], int last if ((strpt=strstr(model,"age*age")) !=0){ printf(" strpt=%s, model=%s\n",strpt, model); if(strpt != model){ - printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \ + printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \ 'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \ corresponding column of parameters.\n",model); - fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \ + fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \ 'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \ corresponding column of parameters.\n",model); fflush(ficlog); - return 1; - } + return 1; + } nagesqr=1; if (strstr(model,"+age*age") !=0) - substrchaine(modelsav, model, "+age*age"); + substrchaine(modelsav, model, "+age*age"); else if (strstr(model,"age*age+") !=0) - substrchaine(modelsav, model, "age*age+"); + substrchaine(modelsav, model, "age*age+"); else - substrchaine(modelsav, model, "age*age"); + substrchaine(modelsav, model, "age*age"); }else nagesqr=0; if (strlen(modelsav) >1){ j=nbocc(modelsav,'+'); /**< j=Number of '+' */ j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */ - cptcovs=j+1-j1; /**< Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =2 */ + cptcovs=j+1-j1; /**< Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2 */ cptcovt= j+1; /* Number of total covariates in the model, not including - * cst, age and age*age - * V1+V1*age+ V3 + V3*V4+age*age=> 4*/ - /* including age products which are counted in cptcovage. - * but the covariates which are products must be treated - * separately: ncovn=4- 2=2 (V1+V3). */ + * cst, age and age*age + * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/ + /* including age products which are counted in cptcovage. + * but the covariates which are products must be treated + * separately: ncovn=4- 2=2 (V1+V3). */ cptcovprod=j1; /**< Number of products V1*V2 +v3*age = 2 */ cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1 */ @@ -7411,8 +7711,8 @@ int decodemodel ( char model[], int last * k= 1 2 3 4 5 6 7 8 * cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8 * covar[k,i], value of kth covariate if not including age for individual i: - * covar[1][i]= (V2), covar[4][i]=(V3), covar[8][i]=(V8) - * Tvar[k] # of the kth covariate: Tvar[1]=2 Tvar[4]=3 Tvar[8]=8 + * covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8) + * Tvar[k] # of the kth covariate: Tvar[1]=2 Tvar[2]=1 Tvar[4]=3 Tvar[8]=8 * if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and * Tage[++cptcovage]=k * if products, new covar are created after ncovcol with k1 @@ -7456,62 +7756,62 @@ int decodemodel ( char model[], int last Tvar[k]=0; cptcovage=0; for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */ - cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' - modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ - if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */ - /* printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/ - /*scanf("%d",i);*/ - if (strchr(strb,'*')) { /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */ - cutl(strc,strd,strb,'*'); /**< strd*strc Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */ - if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */ - /* covar is not filled and then is empty */ - cptcovprod--; - cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */ - Tvar[k]=atoi(stre); /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */ - cptcovage++; /* Sums the number of covariates which include age as a product */ - Tage[cptcovage]=k; /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */ - /*printf("stre=%s ", stre);*/ - } else if (strcmp(strd,"age")==0) { /* or age*Vn */ - cptcovprod--; - cutl(stre,strb,strc,'V'); - Tvar[k]=atoi(stre); - cptcovage++; - Tage[cptcovage]=k; - } else { /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2 strb=V3*V2*/ - /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */ - cptcovn++; - cptcovprodnoage++;k1++; - cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/ - Tvar[k]=ncovcol+k1; /* For model-covariate k tells which data-covariate to use but - because this model-covariate is a construction we invent a new column - ncovcol + k1 - If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2 - Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */ - cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */ - Tprod[k1]=k; /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2 */ - Tvard[k1][1] =atoi(strc); /* m 1 for V1*/ - Tvard[k1][2] =atoi(stre); /* n 4 for V4*/ - k2=k2+2; - Tvar[cptcovt+k2]=Tvard[k1][1]; /* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) */ - Tvar[cptcovt+k2+1]=Tvard[k1][2]; /* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) */ - for (i=1; i<=lastobs;i++){ - /* Computes the new covariate which is a product of - covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */ - covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i]; - } - } /* End age is not in the model */ - } /* End if model includes a product */ - else { /* no more sum */ - /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/ - /* scanf("%d",i);*/ - cutl(strd,strc,strb,'V'); - ks++; /**< Number of simple covariates */ - cptcovn++; - Tvar[k]=atoi(strd); - } - strcpy(modelsav,stra); /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ - /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav); - scanf("%d",i);*/ + cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' + modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ + if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */ + /* printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/ + /*scanf("%d",i);*/ + if (strchr(strb,'*')) { /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */ + cutl(strc,strd,strb,'*'); /**< strd*strc Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */ + if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */ + /* covar is not filled and then is empty */ + cptcovprod--; + cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */ + Tvar[k]=atoi(stre); /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */ + cptcovage++; /* Sums the number of covariates which include age as a product */ + Tage[cptcovage]=k; /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */ + /*printf("stre=%s ", stre);*/ + } else if (strcmp(strd,"age")==0) { /* or age*Vn */ + cptcovprod--; + cutl(stre,strb,strc,'V'); + Tvar[k]=atoi(stre); + cptcovage++; + Tage[cptcovage]=k; + } else { /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2 strb=V3*V2*/ + /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */ + cptcovn++; + cptcovprodnoage++;k1++; + cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/ + Tvar[k]=ncovcol+k1; /* For model-covariate k tells which data-covariate to use but + because this model-covariate is a construction we invent a new column + ncovcol + k1 + If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2 + Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */ + cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */ + Tprod[k1]=k; /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2 */ + Tvard[k1][1] =atoi(strc); /* m 1 for V1*/ + Tvard[k1][2] =atoi(stre); /* n 4 for V4*/ + k2=k2+2; + Tvar[cptcovt+k2]=Tvard[k1][1]; /* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) */ + Tvar[cptcovt+k2+1]=Tvard[k1][2]; /* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) */ + for (i=1; i<=lastobs;i++){ + /* Computes the new covariate which is a product of + covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */ + covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i]; + } + } /* End age is not in the model */ + } /* End if model includes a product */ + else { /* no more sum */ + /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/ + /* scanf("%d",i);*/ + cutl(strd,strc,strb,'V'); + ks++; /**< Number of simple covariates */ + cptcovn++; + Tvar[k]=atoi(strd); + } + strcpy(modelsav,stra); /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ + /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav); + scanf("%d",i);*/ } /* end of loop + on total covariates */ } /* end if strlen(modelsave == 0) age*age might exist */ } /* end if strlen(model == 0) */ @@ -7520,16 +7820,29 @@ int decodemodel ( char model[], int last If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/ /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]); - printf("cptcovprod=%d ", cptcovprod); - fprintf(ficlog,"cptcovprod=%d ", cptcovprod); + printf("cptcovprod=%d ", cptcovprod); + fprintf(ficlog,"cptcovprod=%d ", cptcovprod); - scanf("%d ",i);*/ + scanf("%d ",i);*/ +/* Dispatching in quantitative and time varying covariates */ + for(k=1, ncoveff=0, nqveff=0, ntveff=0, nqtveff=0;k<=cptcovn; k++){ /* or cptocvt */ + if (Tvar[k] <=ncovcol){ + ncoveff++; + }else if( Tvar[k] <=ncovcol+nqv){ + nqveff++; + }else if( Tvar[k] <=ncovcol+nqv+ntv){ + ntveff++; + }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){ + nqtveff++; + }else + printf("Error in effective covariates \n"); + } return (0); /* with covar[new additional covariate if product] and Tage if age */ /*endread:*/ - printf("Exiting decodemodel: "); - return (1); + printf("Exiting decodemodel: "); + return (1); } int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn ) @@ -7864,7 +8177,7 @@ int prevalence_limit(double *p, double * agebase=ageminpar; agelim=agemaxpar; - i1=pow(2,cptcoveff); + i1=pow(2,ncoveff); if (cptcovn < 1){i1=1;} for(k=1; k<=i1;k++){ @@ -7877,7 +8190,7 @@ int prevalence_limit(double *p, double * fprintf(ficrespl,"#******"); printf("#******"); fprintf(ficlog,"#******"); - for(j=1;j<=cptcoveff;j++) { + for(j=1;j<=nqveff;j++) { fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); @@ -7893,7 +8206,7 @@ int prevalence_limit(double *p, double * } fprintf(ficrespl,"#Age "); - for(j=1;j<=cptcoveff;j++) { + for(j=1;j<=nqveff;j++) { fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); } for(i=1; i<=nlstate;i++) fprintf(ficrespl," %d-%d ",i,i); @@ -7903,7 +8216,7 @@ int prevalence_limit(double *p, double * /* for (age=agebase; age<=agebase; age++){ */ prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k); fprintf(ficrespl,"%.0f ",age ); - for(j=1;j<=cptcoveff;j++) + for(j=1;j<=nqveff;j++) fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); tot=0.; for(i=1; i<=nlstate;i++){ @@ -7951,7 +8264,7 @@ int back_prevalence_limit(double *p, dou agelim=agemaxpar; - i1=pow(2,cptcoveff); + i1=pow(2,nqveff); if (cptcovn < 1){i1=1;} for(k=1; k<=i1;k++){ @@ -7964,7 +8277,7 @@ int back_prevalence_limit(double *p, dou fprintf(ficresplb,"#******"); printf("#******"); fprintf(ficlog,"#******"); - for(j=1;j<=cptcoveff;j++) { + for(j=1;j<=nqveff;j++) { fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); @@ -7980,7 +8293,7 @@ int back_prevalence_limit(double *p, dou } fprintf(ficresplb,"#Age "); - for(j=1;j<=cptcoveff;j++) { + for(j=1;j<=nqveff;j++) { fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); } for(i=1; i<=nlstate;i++) fprintf(ficresplb," %d-%d ",i,i); @@ -8002,7 +8315,7 @@ int back_prevalence_limit(double *p, dou bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k); } fprintf(ficresplb,"%.0f ",age ); - for(j=1;j<=cptcoveff;j++) + for(j=1;j<=nqveff;j++) fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); tot=0.; for(i=1; i<=nlstate;i++){ @@ -8050,13 +8363,13 @@ int hPijx(double *p, int bage, int fage) /* hstepm=1; aff par mois*/ pstamp(ficrespij); fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x "); - i1= pow(2,cptcoveff); + i1= pow(2,nqveff); /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */ /* /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */ /* k=k+1; */ - for (k=1; k <= (int) pow(2,cptcoveff); k++){ + for (k=1; k <= (int) pow(2,nqveff); k++){ fprintf(ficrespij,"\n#****** "); - for(j=1;j<=cptcoveff;j++) + for(j=1;j<=nqveff;j++) fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); fprintf(ficrespij,"******\n"); @@ -8122,15 +8435,19 @@ int hPijx(double *p, int bage, int fage) /* hstepm=1; aff par mois*/ pstamp(ficrespijb); fprintf(ficrespijb,"#****** h Pij x Back Probability to be in state i at age x-h being in j at x "); - i1= pow(2,cptcoveff); + i1= pow(2,nqveff); /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */ /* /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */ /* k=k+1; */ - for (k=1; k <= (int) pow(2,cptcoveff); k++){ + for (k=1; k <= (int) pow(2,nqveff); k++){ fprintf(ficrespijb,"\n#****** "); - for(j=1;j<=cptcoveff;j++) + for(j=1;j<=nqveff;j++) fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); fprintf(ficrespijb,"******\n"); + if(invalidvarcomb[k]){ + fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); + continue; + } /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */ for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */ @@ -8445,13 +8762,13 @@ int main(int argc, char *argv[]) }else break; } - if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \ - &ftol, &stepm, &ncovcol, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){ - if (num_filled != 8) { - printf("Not 8 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n"); + if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \ + &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){ + if (num_filled != 11) { + printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1 nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n"); printf("but line=%s\n",line); } - printf("ftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt); + printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt); } /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */ /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */ @@ -8489,8 +8806,8 @@ int main(int argc, char *argv[]) /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */ /* numlinepar=numlinepar+3; /\* In general *\/ */ /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */ - fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model); - fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model); + fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); + fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); fflush(ficlog); /* if(model[0]=='#'|| model[0]== '\0'){ */ if(model[0]=='#'){ @@ -8519,6 +8836,9 @@ int main(int argc, char *argv[]) covar=matrix(0,NCOVMAX,1,n); /**< used in readdata */ + coqvar=matrix(1,nqv,1,n); /**< used in readdata */ + cotvar=ma3x(1,maxwav,1,ntv,1,n); /**< used in readdata */ + cotqvar=ma3x(1,maxwav,1,nqtv,1,n); /**< used in readdata */ cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/ /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5 v1+v2*age+v2*v3 makes cptcovn = 3 @@ -8786,7 +9106,7 @@ Please run with mle=-1 to get a correct /* Main decodemodel */ - if(decodemodel(model, lastobs) == 1) + if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3 = {4, 3, 5}*/ goto end; if((double)(lastobs-imx)/(double)imx > 1.10){ @@ -9014,7 +9334,7 @@ Title=%s
    Datafile=%s Firstpass=%d La and for any valid combination of covariates and prints on file fileres'p'. */ freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \ - firstpass, lastpass, stepm, weightopt, model); + firstpass, lastpass, stepm, weightopt, model); fprintf(fichtm,"\n"); fprintf(fichtm,"
    Total number of observations=%d
    \n\ @@ -9043,7 +9363,7 @@ Interval (in months) between two waves: ageexmed=vector(1,n); agecens=vector(1,n); dcwave=ivector(1,n); - + for (i=1; i<=imx; i++){ dcwave[i]=-1; for (m=firstpass; m<=lastpass; m++) @@ -9288,7 +9608,7 @@ Please run with mle=-1 to get a correct printf("\n"); /*--------- results files --------------*/ - fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate, ndeath, maxwav, weightopt,model); + fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n"); @@ -9543,9 +9863,9 @@ Please run with mle=-1 to get a correct ungetc(c,ficpar); fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj); - fprintf(ficparo,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj); - fprintf(ficlog,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj); - fprintf(ficres,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj); + fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj); + fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj); + fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj); /* day and month of proj2 are not used but only year anproj2.*/ @@ -9635,7 +9955,7 @@ Please run with mle=-1 to get a correct /*if((stepm == 1) && (strcmp(model,".")==0)){*/ if(prevfcast==1){ /* if(stepm ==1){*/ - prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff); + prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, nqveff); } if(backcast==1){ ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath); @@ -9648,12 +9968,12 @@ Please run with mle=-1 to get a correct back_prevalence_limit(p, bprlim, ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj); fclose(ficresplb); - /* hBijx(p, bage, fage, mobaverage); */ - /* fclose(ficrespijb); */ + hBijx(p, bage, fage, mobaverage); + fclose(ficrespijb); free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */ /* prevbackforecast(fileresu, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, mobilavproj, - bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */ + bage, fage, firstpass, lastpass, anback2, p, nqveff); */ free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath); free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath); free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath); @@ -9679,9 +9999,9 @@ Please run with mle=-1 to get a correct printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout); fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog); - for (k=1; k <= (int) pow(2,cptcoveff); k++){ + for (k=1; k <= (int) pow(2,nqveff); k++){ fprintf(ficreseij,"\n#****** "); - for(j=1;j<=cptcoveff;j++) { + for(j=1;j<=nqveff;j++) { fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); } fprintf(ficreseij,"******\n"); @@ -9739,15 +10059,15 @@ Please run with mle=-1 to get a correct /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){ for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/ - for (k=1; k <= (int) pow(2,cptcoveff); k++){ + for (k=1; k <= (int) pow(2,nqveff); k++){ fprintf(ficrest,"\n#****** "); - for(j=1;j<=cptcoveff;j++) + for(j=1;j<=nqveff;j++) fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); fprintf(ficrest,"******\n"); fprintf(ficresstdeij,"\n#****** "); fprintf(ficrescveij,"\n#****** "); - for(j=1;j<=cptcoveff;j++) { + for(j=1;j<=nqveff;j++) { fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); } @@ -9755,7 +10075,7 @@ Please run with mle=-1 to get a correct fprintf(ficrescveij,"******\n"); fprintf(ficresvij,"\n#****** "); - for(j=1;j<=cptcoveff;j++) + for(j=1;j<=nqveff;j++) fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); fprintf(ficresvij,"******\n"); @@ -9865,9 +10185,9 @@ Please run with mle=-1 to get a correct /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){ for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/ - for (k=1; k <= (int) pow(2,cptcoveff); k++){ + for (k=1; k <= (int) pow(2,nqveff); k++){ fprintf(ficresvpl,"\n#****** "); - for(j=1;j<=cptcoveff;j++) + for(j=1;j<=nqveff;j++) fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); fprintf(ficresvpl,"******\n"); @@ -9893,6 +10213,9 @@ Please run with mle=-1 to get a correct free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath); free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath); free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath); + free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n); + free_ma3x(cotvar,1,maxwav,1,ntv,1,n); + free_matrix(coqvar,1,maxwav,1,n); free_matrix(covar,0,NCOVMAX,1,n); free_matrix(matcov,1,npar,1,npar); free_matrix(hess,1,npar,1,npar);
    Tot%.5f%.0f%.0fNanq%.0f%.0fNanq%.0f%.0f%.5f%.0f%.0f