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Diff for /imach/src/imach.c between versions 1.26 and 1.41.2.2

version 1.26, 2002/02/27 15:42:00 version 1.41.2.2, 2003/06/13 07:45:28
Line 14 Line 14
   model. More health states you consider, more time is necessary to reach the    model. More health states you consider, more time is necessary to reach the
   Maximum Likelihood of the parameters involved in the model.  The    Maximum Likelihood of the parameters involved in the model.  The
   simplest model is the multinomial logistic model where pij is the    simplest model is the multinomial logistic model where pij is the
   probabibility to be observed in state j at the second wave    probability to be observed in state j at the second wave
   conditional to be observed in state i at the first wave. Therefore    conditional to be observed in state i at the first wave. Therefore
   the model is: log(pij/pii)= aij + bij*age+ cij*sex + etc , where    the model is: log(pij/pii)= aij + bij*age+ cij*sex + etc , where
   'age' is age and 'sex' is a covariate. If you want to have a more    'age' is age and 'sex' is a covariate. If you want to have a more
Line 56 Line 56
 #include <unistd.h>  #include <unistd.h>
   
 #define MAXLINE 256  #define MAXLINE 256
 #define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"  #define GNUPLOTPROGRAM "wgnuplot"
   /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
 #define FILENAMELENGTH 80  #define FILENAMELENGTH 80
 /*#define DEBUG*/  /*#define DEBUG*/
 #define windows  
   /*#define windows*/
 #define GLOCK_ERROR_NOPATH              -1      /* empty path */  #define GLOCK_ERROR_NOPATH              -1      /* empty path */
 #define GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */  #define GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
   
Line 82  int cptcovn, cptcovage=0, cptcoveff=0,cp Line 84  int cptcovn, cptcovage=0, cptcoveff=0,cp
 int npar=NPARMAX;  int npar=NPARMAX;
 int nlstate=2; /* Number of live states */  int nlstate=2; /* Number of live states */
 int ndeath=1; /* Number of dead states */  int ndeath=1; /* Number of dead states */
 int ncovmodel, ncov;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */  int ncovmodel, ncovcol;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
 int popbased=0;  int popbased=0;
   
 int *wav; /* Number of waves for this individuual 0 is possible */  int *wav; /* Number of waves for this individuual 0 is possible */
Line 94  int **dh; /* dh[mi][i] is number of step Line 96  int **dh; /* dh[mi][i] is number of step
 double jmean; /* Mean space between 2 waves */  double jmean; /* Mean space between 2 waves */
 double **oldm, **newm, **savm; /* Working pointers to matrices */  double **oldm, **newm, **savm; /* Working pointers to matrices */
 double **oldms, **newms, **savms; /* Fixed working pointers to matrices */  double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
 FILE *fic,*ficpar, *ficparo,*ficres,  *ficrespl, *ficrespij, *ficrest,*ficresf;  FILE *fic,*ficpar, *ficparo,*ficres,  *ficrespl, *ficrespij, *ficrest,*ficresf,*ficrespop;
 FILE *ficgp,*ficresprob,*ficpop;  FILE *ficgp,*ficresprob,*ficpop;
 FILE *ficreseij;  FILE *ficreseij;
   char filerese[FILENAMELENGTH];    char filerese[FILENAMELENGTH];
Line 135  int imx; Line 137  int imx;
 int stepm;  int stepm;
 /* Stepm, step in month: minimum step interpolation*/  /* Stepm, step in month: minimum step interpolation*/
   
   int estepm;
   /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
   
 int m,nb;  int m,nb;
 int *num, firstpass=0, lastpass=4,*cod, *ncodemax, *Tage;  int *num, firstpass=0, lastpass=4,*cod, *ncodemax, *Tage;
 double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;  double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
Line 686  double **prevalim(double **prlim, int nl Line 691  double **prevalim(double **prlim, int nl
     
       for (k=1; k<=cptcovn;k++) {        for (k=1; k<=cptcovn;k++) {
         cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]];          cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]];
         /*printf("ij=%d Tvar[k]=%d nbcode=%d cov=%lf\n",ij, Tvar[k],nbcode[Tvar[k]][codtab[ij][Tvar[k]]],cov[2+k]);*/          /*      printf("ij=%d k=%d Tvar[k]=%d nbcode=%d cov=%lf codtab[ij][Tvar[k]]=%d \n",ij,k, Tvar[k],nbcode[Tvar[k]][codtab[ij][Tvar[k]]],cov[2+k], codtab[ij][Tvar[k]]);*/
       }        }
       for (k=1; k<=cptcovage;k++)        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];
         cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];  
       for (k=1; k<=cptcovprod;k++)        for (k=1; k<=cptcovprod;k++)
         cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];          cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];
   
       /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/        /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
       /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/        /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
         /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);      out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
   
     savm=oldm;      savm=oldm;
Line 866  double func( double *x) Line 870  double func( double *x)
   double **out;    double **out;
   double sw; /* Sum of weights */    double sw; /* Sum of weights */
   double lli; /* Individual log likelihood */    double lli; /* Individual log likelihood */
     int s1, s2;
   long ipmx;    long ipmx;
   /*extern weight */    /*extern weight */
   /* We are differentiating ll according to initial status */    /* We are differentiating ll according to initial status */
Line 880  double func( double *x) Line 885  double func( double *x)
     for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];      for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
     for(mi=1; mi<= wav[i]-1; mi++){      for(mi=1; mi<= wav[i]-1; mi++){
       for (ii=1;ii<=nlstate+ndeath;ii++)        for (ii=1;ii<=nlstate+ndeath;ii++)
         for (j=1;j<=nlstate+ndeath;j++) oldm[ii][j]=(ii==j ? 1.0 : 0.0);          for (j=1;j<=nlstate+ndeath;j++){
             oldm[ii][j]=(ii==j ? 1.0 : 0.0);
             savm[ii][j]=(ii==j ? 1.0 : 0.0);
           }
       for(d=0; d<dh[mi][i]; d++){        for(d=0; d<dh[mi][i]; d++){
         newm=savm;          newm=savm;
         cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;          cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
Line 896  double func( double *x) Line 904  double func( double *x)
                 
       } /* end mult */        } /* end mult */
             
       lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);        s1=s[mw[mi][i]][i];
       /* printf(" %f ",out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/        s2=s[mw[mi+1][i]][i];
         if( s2 > nlstate){
           /* i.e. if s2 is a death state and if the date of death is known then the contribution
              to the likelihood is the probability to die between last step unit time and current
              step unit time, which is also the differences between probability to die before dh
              and probability to die before dh-stepm .
              In version up to 0.92 likelihood was computed
              as if date of death was unknown. Death was treated as any other
              health state: the date of the interview describes the actual state
              and not the date of a change in health state. The former idea was
              to consider that at each interview the state was recorded
              (healthy, disable or death) and IMaCh was corrected; but when we
              introduced the exact date of death then we should have modified
              the contribution of an exact death to the likelihood. This new
              contribution is smaller and very dependent of the step unit
              stepm. It is no more the probability to die between last interview
              and month of death but the probability to survive from last
              interview up to one month before death multiplied by the
              probability to die within a month. Thanks to Chris
              Jackson for correcting this bug.  Former versions increased
              mortality artificially. The bad side is that we add another loop
              which slows down the processing. The difference can be up to 10%
              lower mortality.
           */
           lli=log(out[s1][s2] - savm[s1][s2]);
         }else{
           lli=log(out[s1][s2]); /* or     lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); */
           /* printf(" %f ",out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/
         }
       ipmx +=1;        ipmx +=1;
       sw += weight[i];        sw += weight[i];
       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
         /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d lli=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],lli,weight[i],out[s1][s2],savm[s1][s2]);*/
     } /* end of wave */      } /* end of wave */
   } /* end of individual */    } /* end of individual */
   
   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];    for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */    /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */    l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
     /*exit(0);*/
   return -l;    return -l;
 }  }
   
Line 1178  void lubksb(double **a, int n, int *indx Line 1216  void lubksb(double **a, int n, int *indx
 /************ Frequencies ********************/  /************ Frequencies ********************/
 void  freqsummary(char fileres[], int agemin, int agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2,double jprev1, double mprev1,double anprev1,double jprev2, double mprev2,double anprev2)  void  freqsummary(char fileres[], int agemin, int agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2,double jprev1, double mprev1,double anprev1,double jprev2, double mprev2,double anprev2)
 {  /* Some frequencies */  {  /* Some frequencies */
     
   int i, m, jk, k1,i1, j1, bool, z1,z2,j;    int i, m, jk, k1,i1, j1, bool, z1,z2,j;
   double ***freq; /* Frequencies */    double ***freq; /* Frequencies */
   double *pp;    double *pp;
   double pos, k2, dateintsum=0,k2cpt=0;    double pos, k2, dateintsum=0,k2cpt=0;
   FILE *ficresp;    FILE *ficresp;
   char fileresp[FILENAMELENGTH];    char fileresp[FILENAMELENGTH];
    
   pp=vector(1,nlstate);    pp=vector(1,nlstate);
   probs= ma3x(1,AGESUP,1,NCOVMAX, 1,NCOVMAX);    probs= ma3x(1,AGESUP,1,NCOVMAX, 1,NCOVMAX);
   strcpy(fileresp,"p");    strcpy(fileresp,"p");
Line 1196  void  freqsummary(char fileres[], int ag Line 1234  void  freqsummary(char fileres[], int ag
   }    }
   freq= ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,agemin,agemax+3);    freq= ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,agemin,agemax+3);
   j1=0;    j1=0;
    
   j=cptcoveff;    j=cptcoveff;
   if (cptcovn<1) {j=1;ncodemax[1]=1;}    if (cptcovn<1) {j=1;ncodemax[1]=1;}
    
   for(k1=1; k1<=j;k1++){    for(k1=1; k1<=j;k1++){
    for(i1=1; i1<=ncodemax[k1];i1++){      for(i1=1; i1<=ncodemax[k1];i1++){
        j1++;        j1++;
        /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);        /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
          scanf("%d", i);*/          scanf("%d", i);*/
         for (i=-1; i<=nlstate+ndeath; i++)          for (i=-1; i<=nlstate+ndeath; i++)  
          for (jk=-1; jk<=nlstate+ndeath; jk++)            for (jk=-1; jk<=nlstate+ndeath; jk++)  
            for(m=agemin; m <= agemax+3; m++)            for(m=agemin; m <= agemax+3; m++)
              freq[i][jk][m]=0;              freq[i][jk][m]=0;
        
         dateintsum=0;        dateintsum=0;
         k2cpt=0;        k2cpt=0;
        for (i=1; i<=imx; i++) {        for (i=1; i<=imx; i++) {
          bool=1;          bool=1;
          if  (cptcovn>0) {          if  (cptcovn>0) {
            for (z1=1; z1<=cptcoveff; z1++)            for (z1=1; z1<=cptcoveff; z1++)
              if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtab[j1][z1]])              if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtab[j1][z1]])
                bool=0;                bool=0;
          }          }
          if (bool==1) {          if (bool==1) {
            for(m=firstpass; m<=lastpass; m++){            for(m=firstpass; m<=lastpass; m++){
              k2=anint[m][i]+(mint[m][i]/12.);              k2=anint[m][i]+(mint[m][i]/12.);
              if ((k2>=dateprev1) && (k2<=dateprev2)) {              if ((k2>=dateprev1) && (k2<=dateprev2)) {
                if(agev[m][i]==0) agev[m][i]=agemax+1;                if(agev[m][i]==0) agev[m][i]=agemax+1;
                if(agev[m][i]==1) agev[m][i]=agemax+2;                if(agev[m][i]==1) agev[m][i]=agemax+2;
                freq[s[m][i]][s[m+1][i]][(int)agev[m][i]] += weight[i];                if (m<lastpass) {
                freq[s[m][i]][s[m+1][i]][(int) agemax+3] += weight[i];                  freq[s[m][i]][s[m+1][i]][(int)agev[m][i]] += weight[i];
                if ((agev[m][i]>1) && (agev[m][i]< (agemax+3))) {                  freq[s[m][i]][s[m+1][i]][(int) agemax+3] += weight[i];
                  dateintsum=dateintsum+k2;                }
                  k2cpt++;               
                }                if ((agev[m][i]>1) && (agev[m][i]< (agemax+3))) {
                   dateintsum=dateintsum+k2;
              }                  k2cpt++;
            }                }
          }              }
        }            }
           }
         }
                 
        fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);        fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);
   
         if  (cptcovn>0) {        if  (cptcovn>0) {
          fprintf(ficresp, "\n#********** Variable ");          fprintf(ficresp, "\n#********** Variable ");
          for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);          for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
        fprintf(ficresp, "**********\n#");          fprintf(ficresp, "**********\n#");
         }        }
        for(i=1; i<=nlstate;i++)        for(i=1; i<=nlstate;i++)
          fprintf(ficresp, " Age Prev(%d) N(%d) N",i,i);          fprintf(ficresp, " Age Prev(%d) N(%d) N",i,i);
        fprintf(ficresp, "\n");        fprintf(ficresp, "\n");
               
   for(i=(int)agemin; i <= (int)agemax+3; i++){        for(i=(int)agemin; i <= (int)agemax+3; i++){
     if(i==(int)agemax+3)          if(i==(int)agemax+3)
       printf("Total");            printf("Total");
     else          else
       printf("Age %d", i);            printf("Age %d", i);
     for(jk=1; jk <=nlstate ; jk++){          for(jk=1; jk <=nlstate ; jk++){
       for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)            for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
         pp[jk] += freq[jk][m][i];              pp[jk] += freq[jk][m][i];
     }          }
     for(jk=1; jk <=nlstate ; jk++){          for(jk=1; jk <=nlstate ; jk++){
       for(m=-1, pos=0; m <=0 ; m++)            for(m=-1, pos=0; m <=0 ; m++)
         pos += freq[jk][m][i];              pos += freq[jk][m][i];
       if(pp[jk]>=1.e-10)            if(pp[jk]>=1.e-10)
         printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);              printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
       else            else
         printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);              printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
     }          }
   
      for(jk=1; jk <=nlstate ; jk++){          for(jk=1; jk <=nlstate ; jk++){
       for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)            for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)
         pp[jk] += freq[jk][m][i];              pp[jk] += freq[jk][m][i];
      }          }
   
     for(jk=1,pos=0; jk <=nlstate ; jk++)          for(jk=1,pos=0; jk <=nlstate ; jk++)
       pos += pp[jk];            pos += pp[jk];
     for(jk=1; jk <=nlstate ; jk++){          for(jk=1; jk <=nlstate ; jk++){
       if(pos>=1.e-5)            if(pos>=1.e-5)
         printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);              printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
       else            else
         printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);              printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
       if( i <= (int) agemax){            if( i <= (int) agemax){
         if(pos>=1.e-5){              if(pos>=1.e-5){
           fprintf(ficresp," %d %.5f %.0f %.0f",i,pp[jk]/pos, pp[jk],pos);                fprintf(ficresp," %d %.5f %.0f %.0f",i,pp[jk]/pos, pp[jk],pos);
           probs[i][jk][j1]= pp[jk]/pos;                probs[i][jk][j1]= pp[jk]/pos;
           /*printf("\ni=%d jk=%d j1=%d %.5f %.0f %.0f %f",i,jk,j1,pp[jk]/pos, pp[jk],pos,probs[i][jk][j1]);*/                /*printf("\ni=%d jk=%d j1=%d %.5f %.0f %.0f %f",i,jk,j1,pp[jk]/pos, pp[jk],pos,probs[i][jk][j1]);*/
               }
               else
                 fprintf(ficresp," %d NaNq %.0f %.0f",i,pp[jk],pos);
             }
         }          }
       else         
           fprintf(ficresp," %d NaNq %.0f %.0f",i,pp[jk],pos);          for(jk=-1; jk <=nlstate+ndeath; jk++)
             for(m=-1; m <=nlstate+ndeath; m++)
               if(freq[jk][m][i] !=0 ) printf(" %d%d=%.0f",jk,m,freq[jk][m][i]);
           if(i <= (int) agemax)
             fprintf(ficresp,"\n");
           printf("\n");
       }        }
     }      }
     for(jk=-1; jk <=nlstate+ndeath; jk++)    }
       for(m=-1; m <=nlstate+ndeath; m++)  
         if(freq[jk][m][i] !=0 ) printf(" %d%d=%.0f",jk,m,freq[jk][m][i]);  
     if(i <= (int) agemax)  
       fprintf(ficresp,"\n");  
     printf("\n");  
     }  
     }  
  }  
   dateintmean=dateintsum/k2cpt;    dateintmean=dateintsum/k2cpt;
     
   fclose(ficresp);    fclose(ficresp);
   free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath,(int) agemin,(int) agemax+3);    free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath,(int) agemin,(int) agemax+3);
   free_vector(pp,1,nlstate);    free_vector(pp,1,nlstate);
    
   /* End of Freq */    /* End of Freq */
 }  }
   
 /************ Prevalence ********************/  /************ Prevalence ********************/
 void prevalence(int agemin, int agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, double calagedate)  void prevalence(int agemin, float agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, double calagedate)
 {  /* Some frequencies */  {  /* Some frequencies */
     
   int i, m, jk, k1, i1, j1, bool, z1,z2,j;    int i, m, jk, k1, i1, j1, bool, z1,z2,j;
Line 1332  void prevalence(int agemin, int agemax, Line 1373  void prevalence(int agemin, int agemax,
         for (jk=-1; jk<=nlstate+ndeath; jk++)            for (jk=-1; jk<=nlstate+ndeath; jk++)  
           for(m=agemin; m <= agemax+3; m++)            for(m=agemin; m <= agemax+3; m++)
             freq[i][jk][m]=0;              freq[i][jk][m]=0;
             
       for (i=1; i<=imx; i++) {        for (i=1; i<=imx; i++) {
         bool=1;          bool=1;
         if  (cptcovn>0) {          if  (cptcovn>0) {
           for (z1=1; z1<=cptcoveff; z1++)            for (z1=1; z1<=cptcoveff; z1++)
             if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtab[j1][z1]])              if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtab[j1][z1]])
               bool=0;                bool=0;
         }          }
         if (bool==1) {          if (bool==1) {
           for(m=firstpass; m<=lastpass; m++){            for(m=firstpass; m<=lastpass; m++){
             k2=anint[m][i]+(mint[m][i]/12.);              k2=anint[m][i]+(mint[m][i]/12.);
             if ((k2>=dateprev1) && (k2<=dateprev2)) {              if ((k2>=dateprev1) && (k2<=dateprev2)) {
               if(agev[m][i]==0) agev[m][i]=agemax+1;                if(agev[m][i]==0) agev[m][i]=agemax+1;
               if(agev[m][i]==1) agev[m][i]=agemax+2;                if(agev[m][i]==1) agev[m][i]=agemax+2;
               freq[s[m][i]][s[m+1][i]][(int)(agev[m][i]+1-((int)calagedate %12)/12.)] += weight[i];                if (m<lastpass)
               freq[s[m][i]][s[m+1][i]][(int)(agemax+3+1)] += weight[i];                    if (calagedate>0) freq[s[m][i]][s[m+1][i]][(int)(agev[m][i]+1-((int)calagedate %12)/12.)] += weight[i];
                 else
                  freq[s[m][i]][s[m+1][i]][(int)agev[m][i]] += weight[i];
                  freq[s[m][i]][s[m+1][i]][(int)(agemax+3)] += weight[i];
             }              }
           }            }
         }          }
       }        }
        
         for(i=(int)agemin; i <= (int)agemax+3; i++){          for(i=(int)agemin; i <= (int)agemax+3; i++){
           for(jk=1; jk <=nlstate ; jk++){            for(jk=1; jk <=nlstate ; jk++){
             for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)              for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
Line 1381  void prevalence(int agemin, int agemax, Line 1424  void prevalence(int agemin, int agemax,
         }          }
     }      }
   }    }
    
     
   free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath,(int) agemin,(int) agemax+3);    free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath,(int) agemin,(int) agemax+3);
   free_vector(pp,1,nlstate);    free_vector(pp,1,nlstate);
Line 1444  void  concatwav(int wav[], int **dh, int Line 1487  void  concatwav(int wav[], int **dh, int
           if (j >= jmax) jmax=j;            if (j >= jmax) jmax=j;
           if (j <= jmin) jmin=j;            if (j <= jmin) jmin=j;
           sum=sum+j;            sum=sum+j;
           /* if (j<10) printf("j=%d num=%d ",j,i); */            /*if (j<0) printf("j=%d num=%d \n",j,i); */
           }            }
         }          }
         else{          else{
Line 1452  void  concatwav(int wav[], int **dh, int Line 1495  void  concatwav(int wav[], int **dh, int
           k=k+1;            k=k+1;
           if (j >= jmax) jmax=j;            if (j >= jmax) jmax=j;
           else if (j <= jmin)jmin=j;            else if (j <= jmin)jmin=j;
           /*   if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */            /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
           sum=sum+j;            sum=sum+j;
         }          }
         jk= j/stepm;          jk= j/stepm;
Line 1498  void tricode(int *Tvar, int **nbcode, in Line 1541  void tricode(int *Tvar, int **nbcode, in
       for (k=0; k<=19; k++) {        for (k=0; k<=19; k++) {
         if (Ndum[k] != 0) {          if (Ndum[k] != 0) {
           nbcode[Tvar[j]][ij]=k;            nbcode[Tvar[j]][ij]=k;
            
           ij++;            ij++;
         }          }
         if (ij > ncodemax[j]) break;          if (ij > ncodemax[j]) break;
Line 1514  void tricode(int *Tvar, int **nbcode, in Line 1558  void tricode(int *Tvar, int **nbcode, in
   
  ij=1;   ij=1;
  for (i=1; i<=10; i++) {   for (i=1; i<=10; i++) {
    if((Ndum[i]!=0) && (i<=ncov)){     if((Ndum[i]!=0) && (i<=ncovcol)){
      Tvaraff[ij]=i;       Tvaraff[ij]=i;
      ij++;       ij++;
    }     }
Line 1525  void tricode(int *Tvar, int **nbcode, in Line 1569  void tricode(int *Tvar, int **nbcode, in
   
 /*********** Health Expectancies ****************/  /*********** Health Expectancies ****************/
   
 void evsij(char fileres[], double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int ij)  void evsij(char fileres[], double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int ij, int estepm,double delti[],double **matcov )
   
 {  {
   /* Health expectancies */    /* Health expectancies */
   int i, j, nhstepm, hstepm, h;    int i, j, nhstepm, hstepm, h, nstepm, k, cptj;
   double age, agelim,hf;    double age, agelim, hf;
   double ***p3mat;    double ***p3mat,***varhe;
     double **dnewm,**doldm;
     double *xp;
     double **gp, **gm;
     double ***gradg, ***trgradg;
     int theta;
   
     varhe=ma3x(1,nlstate*2,1,nlstate*2,(int) bage, (int) fage);
     xp=vector(1,npar);
     dnewm=matrix(1,nlstate*2,1,npar);
     doldm=matrix(1,nlstate*2,1,nlstate*2);
     
   fprintf(ficreseij,"# Health expectancies\n");    fprintf(ficreseij,"# Health expectancies\n");
   fprintf(ficreseij,"# Age");    fprintf(ficreseij,"# Age");
   for(i=1; i<=nlstate;i++)    for(i=1; i<=nlstate;i++)
     for(j=1; j<=nlstate;j++)      for(j=1; j<=nlstate;j++)
       fprintf(ficreseij," %1d-%1d",i,j);        fprintf(ficreseij," %1d-%1d (SE)",i,j);
   fprintf(ficreseij,"\n");    fprintf(ficreseij,"\n");
   
   hstepm=1*YEARM; /*  Every j years of age (in month) */    if(estepm < stepm){
   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */      printf ("Problem %d lower than %d\n",estepm, stepm);
     }
     else  hstepm=estepm;  
     /* We compute the life expectancy from trapezoids spaced every estepm months
      * This is mainly to measure the difference between two models: for example
      * if stepm=24 months pijx are given only every 2 years and by summing them
      * we are calculating an estimate of the Life Expectancy assuming a linear
      * progression inbetween and thus overestimating or underestimating according
      * to the curvature of the survival function. If, for the same date, we
      * estimate the model with stepm=1 month, we can keep estepm to 24 months
      * to compare the new estimate of Life expectancy with the same linear
      * hypothesis. A more precise result, taking into account a more precise
      * curvature will be obtained if estepm is as small as stepm. */
   
     /* For example we decided to compute the life expectancy with the smallest unit */
     /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm.
        nhstepm is the number of hstepm from age to agelim
        nstepm is the number of stepm from age to agelin.
        Look at hpijx to understand the reason of that which relies in memory size
        and note for a fixed period like estepm months */
     /* We decided (b) to get a life expectancy respecting the most precise curvature of the
        survival function given by stepm (the optimization length). Unfortunately it
        means that if the survival funtion is printed only each two years of age and if
        you sum them up and add 1 year (area under the trapezoids) you won't get the same
        results. So we changed our mind and took the option of the best precision.
     */
     hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */
   
   agelim=AGESUP;    agelim=AGESUP;
   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
     /* nhstepm age range expressed in number of stepm */      /* nhstepm age range expressed in number of stepm */
     nhstepm=(int) rint((agelim-age)*YEARM/stepm);      nstepm=(int) rint((agelim-age)*YEARM/stepm);
     /* Typically if 20 years = 20*12/6=40 stepm */      /* Typically if 20 years nstepm = 20*12/6=40 stepm */
     if (stepm >= YEARM) hstepm=1;      /* if (stepm >= YEARM) hstepm=1;*/
     nhstepm = nhstepm/hstepm;/* Expressed in hstepm, typically 40/4=10 */      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
       gradg=ma3x(0,nhstepm,1,npar,1,nlstate*2);
       gp=matrix(0,nhstepm,1,nlstate*2);
       gm=matrix(0,nhstepm,1,nlstate*2);
   
     /* Computed by stepm unit matrices, product of hstepm matrices, stored      /* Computed by stepm unit matrices, product of hstepm matrices, stored
        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */         in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
     hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, ij);        hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, ij);  
    
   
       hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
   
       /* Computing Variances of health expectancies */
   
        for(theta=1; theta <=npar; theta++){
         for(i=1; i<=npar; i++){
           xp[i] = x[i] + (i==theta ?delti[theta]:0);
         }
         hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);  
    
         cptj=0;
         for(j=1; j<= nlstate; j++){
           for(i=1; i<=nlstate; i++){
             cptj=cptj+1;
             for(h=0, gp[h][cptj]=0.; h<=nhstepm-1; h++){
               gp[h][cptj] = (p3mat[i][j][h]+p3mat[i][j][h+1])/2.;
             }
           }
         }
        
        
         for(i=1; i<=npar; i++)
           xp[i] = x[i] - (i==theta ?delti[theta]:0);
         hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);  
        
         cptj=0;
         for(j=1; j<= nlstate; j++){
           for(i=1;i<=nlstate;i++){
             cptj=cptj+1;
             for(h=0, gm[h][cptj]=0.; h<=nhstepm-1; h++){
               gm[h][cptj] = (p3mat[i][j][h]+p3mat[i][j][h+1])/2.;
             }
           }
         }
        
      
   
         for(j=1; j<= nlstate*2; j++)
           for(h=0; h<=nhstepm-1; h++){
             gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
           }
   
        }
      
   /* End theta */
   
        trgradg =ma3x(0,nhstepm,1,nlstate*2,1,npar);
   
        for(h=0; h<=nhstepm-1; h++)
         for(j=1; j<=nlstate*2;j++)
           for(theta=1; theta <=npar; theta++)
           trgradg[h][j][theta]=gradg[h][theta][j];
   
   
        for(i=1;i<=nlstate*2;i++)
         for(j=1;j<=nlstate*2;j++)
           varhe[i][j][(int)age] =0.;
   
       for(h=0;h<=nhstepm-1;h++){
         for(k=0;k<=nhstepm-1;k++){
           matprod2(dnewm,trgradg[h],1,nlstate*2,1,npar,1,npar,matcov);
           matprod2(doldm,dnewm,1,nlstate*2,1,npar,1,nlstate*2,gradg[k]);
           for(i=1;i<=nlstate*2;i++)
             for(j=1;j<=nlstate*2;j++)
               varhe[i][j][(int)age] += doldm[i][j]*hf*hf;
         }
       }
   
        
       /* Computing expectancies */
     for(i=1; i<=nlstate;i++)      for(i=1; i<=nlstate;i++)
       for(j=1; j<=nlstate;j++)        for(j=1; j<=nlstate;j++)
         for (h=0, eij[i][j][(int)age]=0; h<=nhstepm; h++){          for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
           eij[i][j][(int)age] +=p3mat[i][j][h];            eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
            
   /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
   
         }          }
      
     hf=1;      fprintf(ficreseij,"%3.0f",age );
     if (stepm >= YEARM) hf=stepm/YEARM;      cptj=0;
     fprintf(ficreseij,"%.0f",age );  
     for(i=1; i<=nlstate;i++)      for(i=1; i<=nlstate;i++)
       for(j=1; j<=nlstate;j++){        for(j=1; j<=nlstate;j++){
         fprintf(ficreseij," %.4f", hf*eij[i][j][(int)age]);          cptj++;
           fprintf(ficreseij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[cptj][cptj][(int)age]) );
       }        }
     fprintf(ficreseij,"\n");      fprintf(ficreseij,"\n");
      
       free_matrix(gm,0,nhstepm,1,nlstate*2);
       free_matrix(gp,0,nhstepm,1,nlstate*2);
       free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*2);
       free_ma3x(trgradg,0,nhstepm,1,nlstate*2,1,npar);
     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
   }    }
     free_vector(xp,1,npar);
     free_matrix(dnewm,1,nlstate*2,1,npar);
     free_matrix(doldm,1,nlstate*2,1,nlstate*2);
     free_ma3x(varhe,1,nlstate*2,1,nlstate*2,(int) bage, (int)fage);
 }  }
   
 /************ Variance ******************/  /************ Variance ******************/
 void varevsij(char fileres[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij)  void varevsij(char fileres[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij, int estepm)
 {  {
   /* Variance of health expectancies */    /* Variance of health expectancies */
   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
   double **newm;    double **newm;
   double **dnewm,**doldm;    double **dnewm,**doldm;
   int i, j, nhstepm, hstepm, h;    int i, j, nhstepm, hstepm, h, nstepm ;
   int k, cptcode;    int k, cptcode;
   double *xp;    double *xp;
   double **gp, **gm;    double **gp, **gm;
   double ***gradg, ***trgradg;    double ***gradg, ***trgradg;
   double ***p3mat;    double ***p3mat;
   double age,agelim;    double age,agelim, hf;
   int theta;    int theta;
   
    fprintf(ficresvij,"# Covariances of life expectancies\n");     fprintf(ficresvij,"# Covariances of life expectancies\n");
Line 1600  void varevsij(char fileres[], double *** Line 1767  void varevsij(char fileres[], double ***
   dnewm=matrix(1,nlstate,1,npar);    dnewm=matrix(1,nlstate,1,npar);
   doldm=matrix(1,nlstate,1,nlstate);    doldm=matrix(1,nlstate,1,nlstate);
     
   hstepm=1*YEARM; /* Every year of age */    if(estepm < stepm){
   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */      printf ("Problem %d lower than %d\n",estepm, stepm);
     }
     else  hstepm=estepm;  
     /* For example we decided to compute the life expectancy with the smallest unit */
     /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm.
        nhstepm is the number of hstepm from age to agelim
        nstepm is the number of stepm from age to agelin.
        Look at hpijx to understand the reason of that which relies in memory size
        and note for a fixed period like k years */
     /* We decided (b) to get a life expectancy respecting the most precise curvature of the
        survival function given by stepm (the optimization length). Unfortunately it
        means that if the survival funtion is printed only each two years of age and if
        you sum them up and add 1 year (area under the trapezoids) you won't get the same
        results. So we changed our mind and took the option of the best precision.
     */
     hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */
   agelim = AGESUP;    agelim = AGESUP;
   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
     if (stepm >= YEARM) hstepm=1;      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */  
     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     gradg=ma3x(0,nhstepm,1,npar,1,nlstate);      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
     gp=matrix(0,nhstepm,1,nlstate);      gp=matrix(0,nhstepm,1,nlstate);
Line 1661  void varevsij(char fileres[], double *** Line 1842  void varevsij(char fileres[], double ***
         for(theta=1; theta <=npar; theta++)          for(theta=1; theta <=npar; theta++)
           trgradg[h][j][theta]=gradg[h][theta][j];            trgradg[h][j][theta]=gradg[h][theta][j];
   
       hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
     for(i=1;i<=nlstate;i++)      for(i=1;i<=nlstate;i++)
       for(j=1;j<=nlstate;j++)        for(j=1;j<=nlstate;j++)
         vareij[i][j][(int)age] =0.;          vareij[i][j][(int)age] =0.;
   
     for(h=0;h<=nhstepm;h++){      for(h=0;h<=nhstepm;h++){
       for(k=0;k<=nhstepm;k++){        for(k=0;k<=nhstepm;k++){
         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);          matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);          matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
         for(i=1;i<=nlstate;i++)          for(i=1;i<=nlstate;i++)
           for(j=1;j<=nlstate;j++)            for(j=1;j<=nlstate;j++)
             vareij[i][j][(int)age] += doldm[i][j];              vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
       }        }
     }      }
     h=1;  
     if (stepm >= YEARM) h=stepm/YEARM;  
     fprintf(ficresvij,"%.0f ",age );      fprintf(ficresvij,"%.0f ",age );
     for(i=1; i<=nlstate;i++)      for(i=1; i<=nlstate;i++)
       for(j=1; j<=nlstate;j++){        for(j=1; j<=nlstate;j++){
         fprintf(ficresvij," %.4f", h*vareij[i][j][(int)age]);          fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
       }        }
     fprintf(ficresvij,"\n");      fprintf(ficresvij,"\n");
     free_matrix(gp,0,nhstepm,1,nlstate);      free_matrix(gp,0,nhstepm,1,nlstate);
Line 1778  void varprevlim(char fileres[], double * Line 1960  void varprevlim(char fileres[], double *
 }  }
   
 /************ Variance of one-step probabilities  ******************/  /************ Variance of one-step probabilities  ******************/
 void varprob(char fileres[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij)  void varprob(char fileres[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax)
 {  {
   int i, j;    int i, j, i1, k1, j1, z1;
   int k=0, cptcode;    int k=0, cptcode;
   double **dnewm,**doldm;    double **dnewm,**doldm;
   double *xp;    double *xp;
Line 1795  void varprob(char fileres[], double **ma Line 1977  void varprob(char fileres[], double **ma
   if((ficresprob=fopen(fileresprob,"w"))==NULL) {    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
     printf("Problem with resultfile: %s\n", fileresprob);      printf("Problem with resultfile: %s\n", fileresprob);
   }    }
   printf("Computing variance of one-step probabilities: result on file '%s' \n",fileresprob);    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
     
   fprintf(ficresprob,"#One-step probabilities and standard deviation in parentheses\n");
     fprintf(ficresprob,"# Age");
     for(i=1; i<=nlstate;i++)
       for(j=1; j<=(nlstate+ndeath);j++)
         fprintf(ficresprob," p%1d-%1d (SE)",i,j);
   
   
     fprintf(ficresprob,"\n");
   
   
   xp=vector(1,npar);    xp=vector(1,npar);
   dnewm=matrix(1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);    dnewm=matrix(1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
   doldm=matrix(1,(nlstate+ndeath)*(nlstate+ndeath),1,(nlstate+ndeath)*(nlstate+ndeath));    doldm=matrix(1,(nlstate+ndeath)*(nlstate+ndeath),1,(nlstate+ndeath)*(nlstate+ndeath));
     
   cov[1]=1;    cov[1]=1;
   for (age=bage; age<=fage; age ++){    j=cptcoveff;
     cov[2]=age;    if (cptcovn<1) {j=1;ncodemax[1]=1;}
     gradg=matrix(1,npar,1,9);    j1=0;
     trgradg=matrix(1,9,1,npar);    for(k1=1; k1<=1;k1++){
     gp=vector(1,(nlstate+ndeath)*(nlstate+ndeath));      for(i1=1; i1<=ncodemax[k1];i1++){
     gm=vector(1,(nlstate+ndeath)*(nlstate+ndeath));      j1++;
   
       if  (cptcovn>0) {
         fprintf(ficresprob, "\n#********** Variable ");
         for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
         fprintf(ficresprob, "**********\n#");
       }
         
     for(theta=1; theta <=npar; theta++){        for (age=bage; age<=fage; age ++){
       for(i=1; i<=npar; i++)          cov[2]=age;
         xp[i] = x[i] + (i==theta ?delti[theta]:0);          for (k=1; k<=cptcovn;k++) {
                  cov[2+k]=nbcode[Tvar[k]][codtab[j1][Tvar[k]]];
       pmij(pmmij,cov,ncovmodel,xp,nlstate);           
      
       k=0;  
       for(i=1; i<= (nlstate+ndeath); i++){  
         for(j=1; j<=(nlstate+ndeath);j++){  
            k=k+1;  
           gp[k]=pmmij[i][j];  
         }          }
       }          for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];
           for (k=1; k<=cptcovprod;k++)
       for(i=1; i<=npar; i++)            cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];
         xp[i] = x[i] - (i==theta ?delti[theta]:0);         
           gradg=matrix(1,npar,1,9);
           trgradg=matrix(1,9,1,npar);
           gp=vector(1,(nlstate+ndeath)*(nlstate+ndeath));
           gm=vector(1,(nlstate+ndeath)*(nlstate+ndeath));
      
           for(theta=1; theta <=npar; theta++){
             for(i=1; i<=npar; i++)
               xp[i] = x[i] + (i==theta ?delti[theta]:0);
            
             pmij(pmmij,cov,ncovmodel,xp,nlstate);
            
             k=0;
             for(i=1; i<= (nlstate+ndeath); i++){
               for(j=1; j<=(nlstate+ndeath);j++){
                 k=k+1;
                 gp[k]=pmmij[i][j];
               }
             }
            
             for(i=1; i<=npar; i++)
               xp[i] = x[i] - (i==theta ?delti[theta]:0);
         
             pmij(pmmij,cov,ncovmodel,xp,nlstate);
       pmij(pmmij,cov,ncovmodel,xp,nlstate);            k=0;
       k=0;            for(i=1; i<=(nlstate+ndeath); i++){
       for(i=1; i<=(nlstate+ndeath); i++){              for(j=1; j<=(nlstate+ndeath);j++){
         for(j=1; j<=(nlstate+ndeath);j++){                k=k+1;
           k=k+1;                gm[k]=pmmij[i][j];
           gm[k]=pmmij[i][j];              }
         }            }
       }  
             
        for(i=1; i<= (nlstate+ndeath)*(nlstate+ndeath); i++)            for(i=1; i<= (nlstate+ndeath)*(nlstate+ndeath); i++)
            gradg[theta][i]=(gp[i]-gm[i])/2./delti[theta];                gradg[theta][i]=(gp[i]-gm[i])/2./delti[theta];  
     }          }
   
      for(j=1; j<=(nlstate+ndeath)*(nlstate+ndeath);j++)  
       for(theta=1; theta <=npar; theta++)  
       trgradg[j][theta]=gradg[theta][j];  
    
      matprod2(dnewm,trgradg,1,9,1,npar,1,npar,matcov);  
      matprod2(doldm,dnewm,1,9,1,npar,1,9,gradg);  
   
      pmij(pmmij,cov,ncovmodel,x,nlstate);  
   
      k=0;          for(j=1; j<=(nlstate+ndeath)*(nlstate+ndeath);j++)
      for(i=1; i<=(nlstate+ndeath); i++){            for(theta=1; theta <=npar; theta++)
        for(j=1; j<=(nlstate+ndeath);j++){              trgradg[j][theta]=gradg[theta][j];
          k=k+1;         
          gm[k]=pmmij[i][j];          matprod2(dnewm,trgradg,1,9,1,npar,1,npar,matcov);
           matprod2(doldm,dnewm,1,9,1,npar,1,9,gradg);
          
           pmij(pmmij,cov,ncovmodel,x,nlstate);
          
           k=0;
           for(i=1; i<=(nlstate+ndeath); i++){
             for(j=1; j<=(nlstate+ndeath);j++){
               k=k+1;
               gm[k]=pmmij[i][j];
             }
         }          }
      }  
             
      /*printf("\n%d ",(int)age);       /*printf("\n%d ",(int)age);
      for (i=1; i<=(nlstate+ndeath)*(nlstate+ndeath-1);i++){       for (i=1; i<=(nlstate+ndeath)*(nlstate+ndeath-1);i++){
          
   
        printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
      }*/       }*/
   
   fprintf(ficresprob,"\n%d ",(int)age);          fprintf(ficresprob,"\n%d ",(int)age);
   
   for (i=1; i<=(nlstate+ndeath)*(nlstate+ndeath-1);i++){  
     if (i== 2) fprintf(ficresprob,"%.3e %.3e ",gm[i],doldm[i][i]);  
 if (i== 4) fprintf(ficresprob,"%.3e %.3e ",gm[i],doldm[i][i]);  
   }  
   
           for (i=1; i<=(nlstate+ndeath)*(nlstate+ndeath-1);i++)
             fprintf(ficresprob,"%.3e (%.3e) ",gm[i],sqrt(doldm[i][i]));
    
         }
       }
     free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
     free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
     free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
     free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
 }    }
  free_vector(xp,1,npar);    free_vector(xp,1,npar);
 fclose(ficresprob);    fclose(ficresprob);
    
 }  }
   
 /******************* Printing html file ***********/  /******************* Printing html file ***********/
 void printinghtml(char fileres[], char title[], char datafile[], int firstpass, int lastpass, int stepm, int weightopt, char model[],int imx,int jmin, int jmax, double jmeanint,char optionfile[],char optionfilehtm[] ){  void printinghtml(char fileres[], char title[], char datafile[], int firstpass, \
    int lastpass, int stepm, int weightopt, char model[],\
    int imx,int jmin, int jmax, double jmeanint,char optionfile[], \
    char optionfilehtm[],char rfileres[], char optionfilegnuplot[],\
    char version[], int popforecast, int estepm ){
   int jj1, k1, i1, cpt;    int jj1, k1, i1, cpt;
   FILE *fichtm;    FILE *fichtm;
   /*char optionfilehtm[FILENAMELENGTH];*/    /*char optionfilehtm[FILENAMELENGTH];*/
Line 1894  void printinghtml(char fileres[], char t Line 2107  void printinghtml(char fileres[], char t
     printf("Problem with %s \n",optionfilehtm), exit(0);      printf("Problem with %s \n",optionfilehtm), exit(0);
   }    }
   
  fprintf(fichtm,"<body><ul> <font size=\"6\">Imach, Version 0.7 </font> <hr size=\"2\" color=\"#EC5E5E\">   fprintf(fichtm,"<body> <font size=\"2\">%s </font> <hr size=\"2\" color=\"#EC5E5E\"> \n
 Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=%s<br>  Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=%s<br>\n
   \n
 Total number of observations=%d <br>  Total number of observations=%d <br>\n
 Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>  Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n
 <hr  size=\"2\" color=\"#EC5E5E\">  <hr  size=\"2\" color=\"#EC5E5E\">
 <li>Outputs files<br><br>\n   <ul><li>Outputs files<br>\n
         - Observed prevalence in each state: <a href=\"p%s\">p%s</a> <br>\n   - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n
 - Estimated parameters and the covariance matrix: <a href=\"%s\">%s</a> <br>   - Gnuplot file name: <a href=\"%s\">%s</a><br>\n
         - Stationary prevalence in each state: <a href=\"pl%s\">pl%s</a> <br>   - Observed prevalence in each state: <a href=\"p%s\">p%s</a> <br>\n
         - Transition probabilities: <a href=\"pij%s\">pij%s</a><br>   - Stationary prevalence in each state: <a href=\"pl%s\">pl%s</a> <br>\n
         - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>   - Transition probabilities: <a href=\"pij%s\">pij%s</a><br>\n
         - Life expectancies by age and initial health status: <a href=\"e%s\">e%s</a> <br>   - Life expectancies by age and initial health status (estepm=%2d months): <a href=\"e%s\">e%s</a> <br>\n",version,title,datafile,firstpass,lastpass,stepm, weightopt,model,imx,jmin,jmax,jmean,fileres,fileres,optionfilegnuplot,optionfilegnuplot,fileres,fileres,fileres,fileres,fileres,fileres,estepm,fileres,fileres);
         - Variances of life expectancies by age and initial health status: <a href=\"v%s\">v%s</a><br>  
         - Health expectancies with their variances: <a href=\"t%s\">t%s</a> <br>   fprintf(fichtm,"\n
         - Standard deviation of stationary prevalences: <a href=\"vpl%s\">vpl%s</a> <br>   - Parameter file with estimated parameters and the covariance matrix: <a href=\"%s\">%s</a> <br>\n
         - Prevalences and population forecasting: <a href=\"f%s\">f%s</a> <br>    - Variance of one-step probabilities: <a href=\"prob%s\">prob%s</a> <br>\n
         <br>",title,datafile,firstpass,lastpass,stepm, weightopt,model,imx,jmin,jmax,jmean,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres,fileres);   - Variances of life expectancies by age and initial health status (estepm=%d months): <a href=\"v%s\">v%s</a><br>\n
     - Health expectancies with their variances: <a href=\"t%s\">t%s</a> <br>\n
    - Standard deviation of stationary prevalences: <a href=\"vpl%s\">vpl%s</a> <br>\n",rfileres,rfileres,fileres,fileres, estepm, fileres,fileres,fileres,fileres,fileres,fileres);
   
    if(popforecast==1) fprintf(fichtm,"\n
    - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n
    - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n
           <br>",fileres,fileres,fileres,fileres);
    else
      fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model);
 fprintf(fichtm," <li>Graphs</li><p>");  fprintf(fichtm," <li>Graphs</li><p>");
   
  m=cptcoveff;   m=cptcoveff;
Line 1953  fclose(fichtm); Line 2174  fclose(fichtm);
 }  }
   
 /******************* Gnuplot file **************/  /******************* Gnuplot file **************/
 void printinggnuplot(char fileres[],char optionfilefiname[],char optionfile[],char optionfilegnuplot[], double agemin, double agemax, double fage , char pathc[], double p[]){  void printinggnuplot(char fileres[],char optionfilefiname[],char optionfile[],char optionfilegnuplot[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
   
   int m,cpt,k1,i,k,j,jk,k2,k3,ij,l;    int m,cpt,k1,i,k,j,jk,k2,k3,ij,l;
   
   strcpy(optionfilegnuplot,optionfilefiname);    strcpy(optionfilegnuplot,optionfilefiname);
   strcat(optionfilegnuplot,".plt");    strcat(optionfilegnuplot,".gp.txt");
   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {    if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
     printf("Problem with file %s",optionfilegnuplot);      printf("Problem with file %s",optionfilegnuplot);
   }    }
Line 1972  m=pow(2,cptcoveff); Line 2193  m=pow(2,cptcoveff);
   for (cpt=1; cpt<= nlstate ; cpt ++) {    for (cpt=1; cpt<= nlstate ; cpt ++) {
    for (k1=1; k1<= m ; k1 ++) {     for (k1=1; k1<= m ; k1 ++) {
   
 #ifdef windows       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter gif small size 400,300\nplot [%.f:%.f] \"vpl%s\" every :::%d::%d u 1:2 \"\%%lf",ageminpar,fage,fileres,k1-1,k1-1);
     fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter gif small size 400,300\nplot [%.f:%.f] \"vpl%s\" every :::%d::%d u 1:2 \"\%%lf",agemin,fage,fileres,k1-1,k1-1);  
 #endif  
 #ifdef unix  
 fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nplot [%.f:%.f] \"vpl%s\" u 1:2 \"\%%lf",agemin,fage,fileres);  
 #endif  
   
 for (i=1; i<= nlstate ; i ++) {  for (i=1; i<= nlstate ; i ++) {
   if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");    if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");
Line 1994  for (i=1; i<= nlstate ; i ++) { Line 2210  for (i=1; i<= nlstate ; i ++) {
   else fprintf(ficgp," \%%*lf (\%%*lf)");    else fprintf(ficgp," \%%*lf (\%%*lf)");
 }    }  
      fprintf(ficgp,"\" t\"\" w l 1,\"p%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence \" w l 2",fileres,k1-1,k1-1,2+4*(cpt-1));       fprintf(ficgp,"\" t\"\" w l 1,\"p%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence \" w l 2",fileres,k1-1,k1-1,2+4*(cpt-1));
 #ifdef unix  
 fprintf(ficgp,"\nset ter gif small size 400,300");  
 #endif  
 fprintf(ficgp,"\nset out \"v%s%d%d.gif\" \nreplot\n\n",strtok(optionfile, "."),cpt,k1);  fprintf(ficgp,"\nset out \"v%s%d%d.gif\" \nreplot\n\n",strtok(optionfile, "."),cpt,k1);
    }     }
   }    }
   /*2 eme*/    /*2 eme*/
   
   for (k1=1; k1<= m ; k1 ++) {    for (k1=1; k1<= m ; k1 ++) {
     fprintf(ficgp,"set ylabel \"Years\" \nset ter gif small size 400,300\nplot [%.f:%.f] ",agemin,fage);      fprintf(ficgp,"set ylabel \"Years\" \nset ter gif small size 400,300\nplot [%.f:%.f] ",ageminpar,fage);
         
     for (i=1; i<= nlstate+1 ; i ++) {      for (i=1; i<= nlstate+1 ; i ++) {
       k=2*i;        k=2*i;
Line 2035  fprintf(ficgp,"\nset out \"v%s%d%d.gif\" Line 2249  fprintf(ficgp,"\nset out \"v%s%d%d.gif\"
   
   for (k1=1; k1<= m ; k1 ++) {    for (k1=1; k1<= m ; k1 ++) {
     for (cpt=1; cpt<= nlstate ; cpt ++) {      for (cpt=1; cpt<= nlstate ; cpt ++) {
       k=2+nlstate*(cpt-1);        k=2+nlstate*(2*cpt-2);
       fprintf(ficgp,"set ter gif small size 400,300\nplot [%.f:%.f] \"e%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",agemin,fage,fileres,k1-1,k1-1,k,cpt);        fprintf(ficgp,"set ter gif small size 400,300\nplot [%.f:%.f] \"e%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,fileres,k1-1,k1-1,k,cpt);
         /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
    for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
   fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
   fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
    for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
   fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
   
   */
       for (i=1; i< nlstate ; i ++) {        for (i=1; i< nlstate ; i ++) {
         fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",fileres,k1-1,k1-1,k+i,cpt,i+1);          fprintf(ficgp," ,\"e%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",fileres,k1-1,k1-1,k+2*i,cpt,i+1);
   
       }        }
       fprintf(ficgp,"\nset out \"exp%s%d%d.gif\" \nreplot\n\n",strtok(optionfile, "."),cpt,k1);        fprintf(ficgp,"\nset out \"exp%s%d%d.gif\" \nreplot\n\n",strtok(optionfile, "."),cpt,k1);
     }      }
Line 2048  fprintf(ficgp,"\nset out \"v%s%d%d.gif\" Line 2271  fprintf(ficgp,"\nset out \"v%s%d%d.gif\"
     for (k1=1; k1<= m ; k1 ++) {      for (k1=1; k1<= m ; k1 ++) {
     for (cpt=1; cpt<nlstate ; cpt ++) {      for (cpt=1; cpt<nlstate ; cpt ++) {
       k=3;        k=3;
       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter gif small size 400,300\nplot [%.f:%.f] \"pij%s\" u ($1==%d ? ($3):1/0):($%d/($%d",agemin,agemax,fileres,k1,k+cpt+1,k+1);        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter gif small size 400,300\nplot [%.f:%.f] \"pij%s\" u ($1==%d ? ($3):1/0):($%d/($%d",ageminpar,agemaxpar,fileres,k1,k+cpt+1,k+1);
   
       for (i=1; i< nlstate ; i ++)        for (i=1; i< nlstate ; i ++)
         fprintf(ficgp,"+$%d",k+i+1);          fprintf(ficgp,"+$%d",k+i+1);
Line 2080  fprintf(ficgp,"\nset out \"v%s%d%d.gif\" Line 2303  fprintf(ficgp,"\nset out \"v%s%d%d.gif\"
     }      }
   
     for(jk=1; jk <=m; jk++) {      for(jk=1; jk <=m; jk++) {
   fprintf(ficgp,"\nset ter gif small size 400,300\nset log y\nplot  [%.f:%.f] ",agemin,agemax);    fprintf(ficgp,"\nset ter gif small size 400,300\nset log y\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
    i=1;     i=1;
    for(k2=1; k2<=nlstate; k2++) {     for(k2=1; k2<=nlstate; k2++) {
      k3=i;       k3=i;
Line 2125  ij=1; Line 2348  ij=1;
   
   
 /*************** Moving average **************/  /*************** Moving average **************/
 void movingaverage(double agedeb, double fage,double agemin, double ***mobaverage){  void movingaverage(double agedeb, double fage,double ageminpar, double ***mobaverage){
   
   int i, cpt, cptcod;    int i, cpt, cptcod;
     for (agedeb=agemin; agedeb<=fage; agedeb++)      for (agedeb=ageminpar; agedeb<=fage; agedeb++)
       for (i=1; i<=nlstate;i++)        for (i=1; i<=nlstate;i++)
         for (cptcod=1;cptcod<=ncodemax[cptcov];cptcod++)          for (cptcod=1;cptcod<=ncodemax[cptcov];cptcod++)
           mobaverage[(int)agedeb][i][cptcod]=0.;            mobaverage[(int)agedeb][i][cptcod]=0.;
         
     for (agedeb=agemin+4; agedeb<=fage; agedeb++){      for (agedeb=ageminpar+4; agedeb<=fage; agedeb++){
       for (i=1; i<=nlstate;i++){        for (i=1; i<=nlstate;i++){
         for (cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){          for (cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){
           for (cpt=0;cpt<=4;cpt++){            for (cpt=0;cpt<=4;cpt++){
Line 2146  void movingaverage(double agedeb, double Line 2369  void movingaverage(double agedeb, double
         
 }  }
   
 /***********************************************/  
 /**************** Main Program *****************/  
 /***********************************************/  
   
 int main(int argc, char *argv[])  /************** Forecasting ******************/
 {  prevforecast(char fileres[], double anproj1,double mproj1,double jproj1,double ageminpar, double agemax,double dateprev1, double dateprev2, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anproj2,double p[], int i2){
    
     int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h;
     int *popage;
     double calagedate, agelim, kk1, kk2, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
     double *popeffectif,*popcount;
     double ***p3mat;
     char fileresf[FILENAMELENGTH];
   
   int i,j, k, n=MAXN,iter,m,size,cptcode, cptcod;   agelim=AGESUP;
   double agedeb, agefin,hf;  calagedate=(anproj1+mproj1/12.+jproj1/365.-dateintmean)*YEARM;
   double agemin=1.e20, agemax=-1.e20;  
   
   double fret;    prevalence(ageminpar, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax,mint,anint,dateprev1,dateprev2, calagedate);
   double **xi,tmp,delta;   
    
     strcpy(fileresf,"f");
     strcat(fileresf,fileres);
     if((ficresf=fopen(fileresf,"w"))==NULL) {
       printf("Problem with forecast resultfile: %s\n", fileresf);
     }
     printf("Computing forecasting: result on file '%s' \n", fileresf);
   
   double dum; /* Dummy variable */    if (cptcoveff==0) ncodemax[cptcoveff]=1;
   double ***p3mat;  
   int *indx;  
   char line[MAXLINE], linepar[MAXLINE];  
   char title[MAXLINE];  
   char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH];  
   char optionfilext[10], optionfilefiname[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilegnuplot[FILENAMELENGTH], plotcmd[FILENAMELENGTH];  
    
   char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filereso[FILENAMELENGTH], fileresf[FILENAMELENGTH];  
   
   char filerest[FILENAMELENGTH];    if (mobilav==1) {
   char fileregp[FILENAMELENGTH];      mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
   char popfile[FILENAMELENGTH];      movingaverage(agedeb, fage, ageminpar, mobaverage);
   char path[80],pathc[80],pathcd[80],pathtot[80],model[20];    }
   int firstobs=1, lastobs=10;  
   int sdeb, sfin; /* Status at beginning and end */  
   int c,  h , cpt,l;  
   int ju,jl, mi;  
   int i1,j1, k1,k2,k3,jk,aa,bb, stepsize, ij;  
   int jnais,jdc,jint4,jint1,jint2,jint3,**outcome,**adl,*tab;  
   int mobilav=0,popforecast=0;  
   int hstepm, nhstepm;  
   int *popage;/*boolprev=0 if date and zero if wave*/  
   double jprev1, mprev1,anprev1,jprev2, mprev2,anprev2;  
   
   double bage, fage, age, agelim, agebase;    stepsize=(int) (stepm+YEARM-1)/YEARM;
   double ftolpl=FTOL;    if (stepm<=12) stepsize=1;
   double **prlim;   
   double *severity;    agelim=AGESUP;
   double ***param; /* Matrix of parameters */   
   double  *p;    hstepm=1;
     hstepm=hstepm/stepm;
     yp1=modf(dateintmean,&yp);
     anprojmean=yp;
     yp2=modf((yp1*12),&yp);
     mprojmean=yp;
     yp1=modf((yp2*30.5),&yp);
     jprojmean=yp;
     if(jprojmean==0) jprojmean=1;
     if(mprojmean==0) jprojmean=1;
    
     fprintf(ficresf,"# Estimated date of observed prevalence: %.lf/%.lf/%.lf ",jprojmean,mprojmean,anprojmean);
    
     for(cptcov=1;cptcov<=i2;cptcov++){
       for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){
         k=k+1;
         fprintf(ficresf,"\n#******");
         for(j=1;j<=cptcoveff;j++) {
           fprintf(ficresf," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
         }
         fprintf(ficresf,"******\n");
         fprintf(ficresf,"# StartingAge FinalAge");
         for(j=1; j<=nlstate+ndeath;j++) fprintf(ficresf," P.%d",j);
        
        
         for (cpt=0; cpt<=(anproj2-anproj1);cpt++) {
           fprintf(ficresf,"\n");
           fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+cpt);  
   
           for (agedeb=(fage-((int)calagedate %12/12.)); agedeb>=(ageminpar-((int)calagedate %12)/12.); agedeb--){
             nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);
             nhstepm = nhstepm/hstepm;
            
             p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             oldm=oldms;savm=savms;
             hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
          
             for (h=0; h<=nhstepm; h++){
               if (h==(int) (calagedate+YEARM*cpt)) {
                 fprintf(ficresf,"\n %.f %.f ",anproj1+cpt,agedeb+h*hstepm/YEARM*stepm);
               }
               for(j=1; j<=nlstate+ndeath;j++) {
                 kk1=0.;kk2=0;
                 for(i=1; i<=nlstate;i++) {              
                   if (mobilav==1)
                     kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod];
                   else {
                     kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod];
                   }
                  
                 }
                 if (h==(int)(calagedate+12*cpt)){
                   fprintf(ficresf," %.3f", kk1);
                          
                 }
               }
             }
             free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           }
         }
       }
     }
          
     if (mobilav==1) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
   
     fclose(ficresf);
   }
   /************** Forecasting ******************/
   populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){
    
     int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h;
     int *popage;
     double calagedate, agelim, kk1, kk2, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
     double *popeffectif,*popcount;
     double ***p3mat,***tabpop,***tabpopprev;
     char filerespop[FILENAMELENGTH];
   
     tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     agelim=AGESUP;
     calagedate=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM;
    
     prevalence(ageminpar, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax,mint,anint,dateprev1,dateprev2, calagedate);
    
    
     strcpy(filerespop,"pop");
     strcat(filerespop,fileres);
     if((ficrespop=fopen(filerespop,"w"))==NULL) {
       printf("Problem with forecast resultfile: %s\n", filerespop);
     }
     printf("Computing forecasting: result on file '%s' \n", filerespop);
   
     if (cptcoveff==0) ncodemax[cptcoveff]=1;
   
     if (mobilav==1) {
       mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       movingaverage(agedeb, fage, ageminpar, mobaverage);
     }
   
     stepsize=(int) (stepm+YEARM-1)/YEARM;
     if (stepm<=12) stepsize=1;
    
     agelim=AGESUP;
    
     hstepm=1;
     hstepm=hstepm/stepm;
    
     if (popforecast==1) {
       if((ficpop=fopen(popfile,"r"))==NULL) {
         printf("Problem with population file : %s\n",popfile);exit(0);
       }
       popage=ivector(0,AGESUP);
       popeffectif=vector(0,AGESUP);
       popcount=vector(0,AGESUP);
      
       i=1;  
       while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1;
      
       imx=i;
       for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i];
     }
   
     for(cptcov=1;cptcov<=i2;cptcov++){
      for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){
         k=k+1;
         fprintf(ficrespop,"\n#******");
         for(j=1;j<=cptcoveff;j++) {
           fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
         }
         fprintf(ficrespop,"******\n");
         fprintf(ficrespop,"# Age");
         for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j);
         if (popforecast==1)  fprintf(ficrespop," [Population]");
        
         for (cpt=0; cpt<=0;cpt++) {
           fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);  
          
           for (agedeb=(fage-((int)calagedate %12/12.)); agedeb>=(ageminpar-((int)calagedate %12)/12.); agedeb--){
             nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);
             nhstepm = nhstepm/hstepm;
            
             p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             oldm=oldms;savm=savms;
             hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
          
             for (h=0; h<=nhstepm; h++){
               if (h==(int) (calagedate+YEARM*cpt)) {
                 fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm);
               }
               for(j=1; j<=nlstate+ndeath;j++) {
                 kk1=0.;kk2=0;
                 for(i=1; i<=nlstate;i++) {              
                   if (mobilav==1)
                     kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod];
                   else {
                     kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod];
                   }
                 }
                 if (h==(int)(calagedate+12*cpt)){
                   tabpop[(int)(agedeb)][j][cptcod]=kk1;
                     /*fprintf(ficrespop," %.3f", kk1);
                       if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*/
                 }
               }
               for(i=1; i<=nlstate;i++){
                 kk1=0.;
                   for(j=1; j<=nlstate;j++){
                     kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];
                   }
                     tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedate+12*cpt)*hstepm/YEARM*stepm-1)];
               }
   
               if (h==(int)(calagedate+12*cpt)) for(j=1; j<=nlstate;j++)
                 fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]);
             }
             free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           }
         }
    
     /******/
   
         for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {
           fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);  
           for (agedeb=(fage-((int)calagedate %12/12.)); agedeb>=(ageminpar-((int)calagedate %12)/12.); agedeb--){
             nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);
             nhstepm = nhstepm/hstepm;
            
             p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             oldm=oldms;savm=savms;
             hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
             for (h=0; h<=nhstepm; h++){
               if (h==(int) (calagedate+YEARM*cpt)) {
                 fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm);
               }
               for(j=1; j<=nlstate+ndeath;j++) {
                 kk1=0.;kk2=0;
                 for(i=1; i<=nlstate;i++) {              
                   kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];    
                 }
                 if (h==(int)(calagedate+12*cpt)) fprintf(ficresf," %15.2f", kk1);
               }
             }
             free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           }
         }
      }
     }
    
     if (mobilav==1) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
   
     if (popforecast==1) {
       free_ivector(popage,0,AGESUP);
       free_vector(popeffectif,0,AGESUP);
       free_vector(popcount,0,AGESUP);
     }
     free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     fclose(ficrespop);
   }
   
   /***********************************************/
   /**************** Main Program *****************/
   /***********************************************/
   
   int main(int argc, char *argv[])
   {
   
     int i,j, k, n=MAXN,iter,m,size,cptcode, cptcod;
     double agedeb, agefin,hf;
     double ageminpar=1.e20,agemin=1.e20, agemaxpar=-1.e20, agemax=-1.e20;
   
     double fret;
     double **xi,tmp,delta;
   
     double dum; /* Dummy variable */
     double ***p3mat;
     int *indx;
     char line[MAXLINE], linepar[MAXLINE];
     char title[MAXLINE];
     char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH];
     char optionfilext[10], optionfilefiname[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilegnuplot[FILENAMELENGTH], plotcmd[FILENAMELENGTH];
    
     char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
   
     char filerest[FILENAMELENGTH];
     char fileregp[FILENAMELENGTH];
     char popfile[FILENAMELENGTH];
     char path[80],pathc[80],pathcd[80],pathtot[80],model[20];
     int firstobs=1, lastobs=10;
     int sdeb, sfin; /* Status at beginning and end */
     int c,  h , cpt,l;
     int ju,jl, mi;
     int i1,j1, k1,k2,k3,jk,aa,bb, stepsize, ij;
     int jnais,jdc,jint4,jint1,jint2,jint3,**outcome,**adl,*tab;
     int mobilav=0,popforecast=0;
     int hstepm, nhstepm;
     double jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,jpyram, mpyram,anpyram,jpyram1, mpyram1,anpyram1, calagedate;
   
     double bage, fage, age, agelim, agebase;
     double ftolpl=FTOL;
     double **prlim;
     double *severity;
     double ***param; /* Matrix of parameters */
     double  *p;
   double **matcov; /* Matrix of covariance */    double **matcov; /* Matrix of covariance */
   double ***delti3; /* Scale */    double ***delti3; /* Scale */
   double *delti; /* Scale */    double *delti; /* Scale */
Line 2198  int main(int argc, char *argv[]) Line 2676  int main(int argc, char *argv[])
   double **varpl; /* Variances of prevalence limits by age */    double **varpl; /* Variances of prevalence limits by age */
   double *epj, vepp;    double *epj, vepp;
   double kk1, kk2;    double kk1, kk2;
   double *popeffectif,*popcount;    double dateprev1, dateprev2,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2;
   double dateprev1, dateprev2,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,jprojmean,mprojmean,anprojmean, calagedate;   
   double yp,yp1,yp2;  
   
   char version[80]="Imach version 0.7, February 2002, INED-EUROREVES ";    char version[80]="Imach version 0.8a1, June 2003, INED-EUROREVES ";
   char *alph[]={"a","a","b","c","d","e"}, str[4];    char *alph[]={"a","a","b","c","d","e"}, str[4];
   
   
Line 2215  int main(int argc, char *argv[]) Line 2692  int main(int argc, char *argv[])
   struct timeval start_time, end_time;    struct timeval start_time, end_time;
     
   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */    gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
     getcwd(pathcd, size);
   
   printf("\n%s",version);    printf("\n%s",version);
   if(argc <=1){    if(argc <=1){
Line 2263  int main(int argc, char *argv[]) Line 2740  int main(int argc, char *argv[])
   }    }
   ungetc(c,ficpar);    ungetc(c,ficpar);
   
   fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncov=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncov, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model);    fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model);
   printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncov=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncov, nlstate,ndeath, maxwav, mle, weightopt,model);    printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model);
   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncov=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncov,nlstate,ndeath,maxwav, mle, weightopt,model);    fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model);
 while((c=getc(ficpar))=='#' && c!= EOF){  while((c=getc(ficpar))=='#' && c!= EOF){
     ungetc(c,ficpar);      ungetc(c,ficpar);
     fgets(line, MAXLINE, ficpar);      fgets(line, MAXLINE, ficpar);
Line 2370  while((c=getc(ficpar))=='#' && c!= EOF){ Line 2847  while((c=getc(ficpar))=='#' && c!= EOF){
   printf("\n");    printf("\n");
   
   
     /*-------- data file ----------*/      /*-------- Rewriting paramater file ----------*/
     if((ficres =fopen(fileres,"w"))==NULL) {       strcpy(rfileres,"r");    /* "Rparameterfile */
       printf("Problem with resultfile: %s\n", fileres);goto end;       strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
        strcat(rfileres,".");    /* */
        strcat(rfileres,optionfilext);    /* Other files have txt extension */
       if((ficres =fopen(rfileres,"w"))==NULL) {
         printf("Problem writing new parameter file: %s\n", fileres);goto end;
     }      }
     fprintf(ficres,"#%s\n",version);      fprintf(ficres,"#%s\n",version);
         
       /*-------- data file ----------*/
     if((fic=fopen(datafile,"r"))==NULL)    {      if((fic=fopen(datafile,"r"))==NULL)    {
       printf("Problem with datafile: %s\n", datafile);goto end;        printf("Problem with datafile: %s\n", datafile);goto end;
     }      }
Line 2417  while((c=getc(ficpar))=='#' && c!= EOF){ Line 2899  while((c=getc(ficpar))=='#' && c!= EOF){
         cutv(stra, strb,line,' '); moisnais[i]=(double)(atoi(strb)); strcpy(line,stra);          cutv(stra, strb,line,' '); moisnais[i]=(double)(atoi(strb)); strcpy(line,stra);
   
         cutv(stra, strb,line,' '); weight[i]=(double)(atoi(strb)); strcpy(line,stra);          cutv(stra, strb,line,' '); weight[i]=(double)(atoi(strb)); strcpy(line,stra);
         for (j=ncov;j>=1;j--){          for (j=ncovcol;j>=1;j--){
           cutv(stra, strb,line,' '); covar[j][i]=(double)(atoi(strb)); strcpy(line,stra);            cutv(stra, strb,line,' '); covar[j][i]=(double)(atoi(strb)); strcpy(line,stra);
         }          }
         num[i]=atol(stra);          num[i]=atol(stra);
Line 2436  while((c=getc(ficpar))=='#' && c!= EOF){ Line 2918  while((c=getc(ficpar))=='#' && c!= EOF){
     if ((s[1][i]==3) && (s[2][i]==2)) s[2][i]=3;      if ((s[1][i]==3) && (s[2][i]==2)) s[2][i]=3;
     if ((s[2][i]==3) && (s[3][i]==2)) s[3][i]=3;      if ((s[2][i]==3) && (s[3][i]==2)) s[3][i]=3;
     if ((s[3][i]==3) && (s[4][i]==2)) s[4][i]=3;      if ((s[3][i]==3) && (s[4][i]==2)) s[4][i]=3;
     }      }*/
      /*  for (i=1; i<=imx; i++){
     for (i=1; i<=imx; i++)       if (s[4][i]==9)  s[4][i]=-1;
     if (covar[1][i]==0) printf("%d %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]), (weight[i]), (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i]));*/       printf("%d %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]), (weight[i]), (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i]));}*/
    
    
   /* Calculation of the number of parameter from char model*/    /* Calculation of the number of parameter from char model*/
   Tvar=ivector(1,15);    Tvar=ivector(1,15);
   Tprod=ivector(1,15);    Tprod=ivector(1,15);
Line 2455  while((c=getc(ficpar))=='#' && c!= EOF){ Line 2938  while((c=getc(ficpar))=='#' && c!= EOF){
     cptcovn=j+1;      cptcovn=j+1;
     cptcovprod=j1;      cptcovprod=j1;
         
      
     strcpy(modelsav,model);      strcpy(modelsav,model);
     if ((strcmp(model,"age")==0) || (strcmp(model,"age*age")==0)){      if ((strcmp(model,"age")==0) || (strcmp(model,"age*age")==0)){
       printf("Error. Non available option model=%s ",model);        printf("Error. Non available option model=%s ",model);
Line 2486  while((c=getc(ficpar))=='#' && c!= EOF){ Line 2968  while((c=getc(ficpar))=='#' && c!= EOF){
         }          }
         else {          else {
           cutv(strb,stre,strc,'V');            cutv(strb,stre,strc,'V');
           Tvar[i]=ncov+k1;            Tvar[i]=ncovcol+k1;
           cutv(strb,strc,strd,'V');            cutv(strb,strc,strd,'V');
           Tprod[k1]=i;            Tprod[k1]=i;
           Tvard[k1][1]=atoi(strc);            Tvard[k1][1]=atoi(strc);
Line 2494  while((c=getc(ficpar))=='#' && c!= EOF){ Line 2976  while((c=getc(ficpar))=='#' && c!= EOF){
           Tvar[cptcovn+k2]=Tvard[k1][1];            Tvar[cptcovn+k2]=Tvard[k1][1];
           Tvar[cptcovn+k2+1]=Tvard[k1][2];            Tvar[cptcovn+k2+1]=Tvard[k1][2];
           for (k=1; k<=lastobs;k++)            for (k=1; k<=lastobs;k++)
             covar[ncov+k1][k]=covar[atoi(stre)][k]*covar[atoi(strc)][k];              covar[ncovcol+k1][k]=covar[atoi(stre)][k]*covar[atoi(strc)][k];
           k1++;            k1++;
           k2=k2+2;            k2=k2+2;
         }          }
Line 2511  while((c=getc(ficpar))=='#' && c!= EOF){ Line 2993  while((c=getc(ficpar))=='#' && c!= EOF){
     }      }
 }  }
     
   /*printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);    /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
   printf("cptcovprod=%d ", cptcovprod);    printf("cptcovprod=%d ", cptcovprod);
   scanf("%d ",i);*/    scanf("%d ",i);*/
     fclose(fic);      fclose(fic);
Line 2523  while((c=getc(ficpar))=='#' && c!= EOF){ Line 3005  while((c=getc(ficpar))=='#' && c!= EOF){
     /*-calculation of age at interview from date of interview and age at death -*/      /*-calculation of age at interview from date of interview and age at death -*/
     agev=matrix(1,maxwav,1,imx);      agev=matrix(1,maxwav,1,imx);
   
    for (i=1; i<=imx; i++)      for (i=1; i<=imx; i++) {
      for(m=2; (m<= maxwav); m++)        for(m=2; (m<= maxwav); m++) {
        if ((mint[m][i]== 99) && (s[m][i] <= nlstate)){         if ((mint[m][i]== 99) && (s[m][i] <= nlstate)){
          anint[m][i]=9999;           anint[m][i]=9999;
          s[m][i]=-1;           s[m][i]=-1;
        }         }
           if(moisdc[i]==99 && andc[i]==9999 & s[m][i]>nlstate) s[m][i]=-1;
         }
       }
   
     for (i=1; i<=imx; i++)  {      for (i=1; i<=imx; i++)  {
       agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);        agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
       for(m=1; (m<= maxwav); m++){        for(m=1; (m<= maxwav); m++){
         if(s[m][i] >0){          if(s[m][i] >0){
           if (s[m][i] == nlstate+1) {            if (s[m][i] >= nlstate+1) {
             if(agedc[i]>0)              if(agedc[i]>0)
               if(moisdc[i]!=99 && andc[i]!=9999)                if(moisdc[i]!=99 && andc[i]!=9999)
               agev[m][i]=agedc[i];                  agev[m][i]=agedc[i];
             else {              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
              else {
               if (andc[i]!=9999){                if (andc[i]!=9999){
               printf("Warning negative age at death: %d line:%d\n",num[i],i);                printf("Warning negative age at death: %d line:%d\n",num[i],i);
               agev[m][i]=-1;                agev[m][i]=-1;
Line 2613  printf("Total number of individuals= %d, Line 3099  printf("Total number of individuals= %d,
        for(j=1; j <= ncodemax[k]; j++){         for(j=1; j <= ncodemax[k]; j++){
          for(cpt=1; cpt <=(m/pow(2,cptcoveff+1-k)); cpt++){           for(cpt=1; cpt <=(m/pow(2,cptcoveff+1-k)); cpt++){
            h++;             h++;
            if (h>m) h=1;codtab[h][k]=j;             if (h>m) h=1;codtab[h][k]=j;codtab[h][Tvar[k]]=j;
              /*  printf("h=%d k=%d j=%d codtab[h][k]=%d tvar[k]=%d \n",h, k,j,codtab[h][k],Tvar[k]);*/
          }           }
        }         }
      }       }
    }     }
      /* printf("codtab[1][2]=%d codtab[2][2]=%d",codtab[1][2],codtab[2][2]);
         codtab[1][2]=1;codtab[2][2]=2; */
    /*for(i=1; i <=m ;i++){     /* for(i=1; i <=m ;i++){
      for(k=1; k <=cptcovn; k++){        for(k=1; k <=cptcovn; k++){
        printf("i=%d k=%d %d %d",i,k,codtab[i][k], cptcoveff);        printf("i=%d k=%d %d %d ",i,k,codtab[i][k], cptcoveff);
      }        }
      printf("\n");        printf("\n");
    }        }
    scanf("%d",i);*/        scanf("%d",i);*/
         
    /* Calculates basic frequencies. Computes observed prevalence at single age     /* Calculates basic frequencies. Computes observed prevalence at single age
        and prints on file fileres'p'. */         and prints on file fileres'p'. */
Line 2648  printf("Total number of individuals= %d, Line 3135  printf("Total number of individuals= %d,
     }      }
         
     /*--------- results files --------------*/      /*--------- results files --------------*/
     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncov=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncov, nlstate, ndeath, maxwav, mle,weightopt,model);      fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate, ndeath, maxwav, weightopt,model);
     
   
    jk=1;     jk=1;
    fprintf(ficres,"# Parameters\n");     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
    printf("# Parameters\n");     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
    for(i=1,jk=1; i <=nlstate; i++){     for(i=1,jk=1; i <=nlstate; i++){
      for(k=1; k <=(nlstate+ndeath); k++){       for(k=1; k <=(nlstate+ndeath); k++){
        if (k != i)         if (k != i)
Line 2675  printf("Total number of individuals= %d, Line 3162  printf("Total number of individuals= %d,
     ftolhess=ftol; /* Usually correct */      ftolhess=ftol; /* Usually correct */
     hesscov(matcov, p, npar, delti, ftolhess, func);      hesscov(matcov, p, npar, delti, ftolhess, func);
  }   }
     fprintf(ficres,"# Scales\n");      fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
     printf("# Scales\n");      printf("# Scales (for hessian or gradient estimation)\n");
      for(i=1,jk=1; i <=nlstate; i++){       for(i=1,jk=1; i <=nlstate; i++){
       for(j=1; j <=nlstate+ndeath; j++){        for(j=1; j <=nlstate+ndeath; j++){
         if (j!=i) {          if (j!=i) {
Line 2694  printf("Total number of individuals= %d, Line 3181  printf("Total number of individuals= %d,
      }       }
         
     k=1;      k=1;
     fprintf(ficres,"# Covariance\n");      fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
     printf("# Covariance\n");      printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
     for(i=1;i<=npar;i++){      for(i=1;i<=npar;i++){
       /*  if (k>nlstate) k=1;        /*  if (k>nlstate) k=1;
       i1=(i-1)/(ncovmodel*nlstate)+1;        i1=(i-1)/(ncovmodel*nlstate)+1;
Line 2719  printf("Total number of individuals= %d, Line 3206  printf("Total number of individuals= %d,
       fputs(line,ficparo);        fputs(line,ficparo);
     }      }
     ungetc(c,ficpar);      ungetc(c,ficpar);
        estepm=0;
     fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf\n",&agemin,&agemax, &bage, &fage);      fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm);
          if (estepm==0 || estepm < stepm) estepm=stepm;
     if (fage <= 2) {      if (fage <= 2) {
       bage = agemin;        bage = ageminpar;
       fage = agemax;        fage = agemaxpar;
     }      }
         
     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");      fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f\n",agemin,agemax,bage,fage);      fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d\n",ageminpar,agemaxpar,bage,fage, estepm);
     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f\n",agemin,agemax,bage,fage);      fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d\n",ageminpar,agemaxpar,bage,fage, estepm);
     
     while((c=getc(ficpar))=='#' && c!= EOF){      while((c=getc(ficpar))=='#' && c!= EOF){
     ungetc(c,ficpar);      ungetc(c,ficpar);
Line 2756  printf("Total number of individuals= %d, Line 3243  printf("Total number of individuals= %d,
    dateprev2=anprev2+mprev2/12.+jprev2/365.;     dateprev2=anprev2+mprev2/12.+jprev2/365.;
   
   fscanf(ficpar,"pop_based=%d\n",&popbased);    fscanf(ficpar,"pop_based=%d\n",&popbased);
    fprintf(ficparo,"pop_based=%d\n",popbased);      fprintf(ficparo,"pop_based=%d\n",popbased);  
    fprintf(ficres,"pop_based=%d\n",popbased);      fprintf(ficres,"pop_based=%d\n",popbased);  
    
   while((c=getc(ficpar))=='#' && c!= EOF){    while((c=getc(ficpar))=='#' && c!= EOF){
     ungetc(c,ficpar);      ungetc(c,ficpar);
     fgets(line, MAXLINE, ficpar);      fgets(line, MAXLINE, ficpar);
Line 2766  printf("Total number of individuals= %d, Line 3253  printf("Total number of individuals= %d,
     fputs(line,ficparo);      fputs(line,ficparo);
   }    }
   ungetc(c,ficpar);    ungetc(c,ficpar);
   fscanf(ficpar,"popforecast=%d popfile=%s starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mov_average=%d\n",&popforecast,popfile,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilav);  
 fprintf(ficparo,"popforecast=%d popfile=%s starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mov_average=%d\n",popforecast,popfile,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilav);    fscanf(ficpar,"starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mov_average=%d\n",&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilav);
 fprintf(ficres,"popforecast=%d popfile=%s starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mov_average=%d\n",popforecast,popfile,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilav);  fprintf(ficparo,"starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mov_average=%d\n",jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilav);
   fprintf(ficres,"starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mov_average=%d\n",jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilav);
   
   
   while((c=getc(ficpar))=='#' && c!= EOF){
       ungetc(c,ficpar);
       fgets(line, MAXLINE, ficpar);
       puts(line);
       fputs(line,ficparo);
     }
     ungetc(c,ficpar);
   
     fscanf(ficpar,"popforecast=%d popfile=%s popfiledate=%lf/%lf/%lf last-popfiledate=%lf/%lf/%lf\n",&popforecast,popfile,&jpyram,&mpyram,&anpyram,&jpyram1,&mpyram1,&anpyram1);
     fprintf(ficparo,"popforecast=%d popfile=%s popfiledate=%.lf/%.lf/%.lf last-popfiledate=%.lf/%.lf/%.lf\n",popforecast,popfile,jpyram,mpyram,anpyram,jpyram1,mpyram1,anpyram1);
     fprintf(ficres,"popforecast=%d popfile=%s popfiledate=%.lf/%.lf/%.lf last-popfiledate=%.lf/%.lf/%.lf\n",popforecast,popfile,jpyram,mpyram,anpyram,jpyram1,mpyram1,anpyram1);
   
  freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax,mint,anint,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);   freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax,mint,anint,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);
   
 /*------------ gnuplot -------------*/  /*------------ gnuplot -------------*/
  printinggnuplot(fileres,optionfilefiname,optionfile,optionfilegnuplot, agemin,agemax,fage, pathc,p);   printinggnuplot(fileres,optionfilefiname,optionfile,optionfilegnuplot, ageminpar,agemaxpar,fage, pathc,p);
     
 /*------------ free_vector  -------------*/  /*------------ free_vector  -------------*/
  chdir(path);   chdir(path);
Line 2786  fprintf(ficres,"popforecast=%d popfile=% Line 3287  fprintf(ficres,"popforecast=%d popfile=%
  /*free_matrix(covar,1,NCOVMAX,1,n);*/   /*free_matrix(covar,1,NCOVMAX,1,n);*/
  fclose(ficparo);   fclose(ficparo);
  fclose(ficres);   fclose(ficres);
    
   /* Reads comments: lines beginning with '#' */  
   while((c=getc(ficpar))=='#' && c!= EOF){  
     ungetc(c,ficpar);  
     fgets(line, MAXLINE, ficpar);  
     puts(line);  
     fputs(line,ficparo);  
   }  
   ungetc(c,ficpar);  
    
   fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf\n",&agemin,&agemax, &bage, &fage);  
   printf("agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f\n",agemin,agemax, bage, fage);  
   fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f\n",agemin,agemax,bage,fage);  
 /*--------- index.htm --------*/  /*--------- index.htm --------*/
   
   printinghtml(fileres,title,datafile, firstpass, lastpass, stepm, weightopt,model,imx,jmin,jmax,jmean,optionfile,optionfilehtm);    printinghtml(fileres,title,datafile, firstpass, lastpass, stepm, weightopt,model,imx,jmin,jmax,jmean,optionfile,optionfilehtm,rfileres,optionfilegnuplot,version,popforecast,estepm);
   
     
   /*--------------- Prevalence limit --------------*/    /*--------------- Prevalence limit --------------*/
Line 2824  fprintf(ficres,"popforecast=%d popfile=% Line 3313  fprintf(ficres,"popforecast=%d popfile=%
   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */    savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */    oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
   k=0;    k=0;
   agebase=agemin;    agebase=ageminpar;
   agelim=agemax;    agelim=agemaxpar;
   ftolpl=1.e-10;    ftolpl=1.e-10;
   i1=cptcoveff;    i1=cptcoveff;
   if (cptcovn < 1){i1=1;}    if (cptcovn < 1){i1=1;}
Line 2885  fprintf(ficres,"popforecast=%d popfile=% Line 3374  fprintf(ficres,"popforecast=%d popfile=%
             for(j=1; j<=nlstate+ndeath;j++)              for(j=1; j<=nlstate+ndeath;j++)
               fprintf(ficrespij," %1d-%1d",i,j);                fprintf(ficrespij," %1d-%1d",i,j);
           fprintf(ficrespij,"\n");            fprintf(ficrespij,"\n");
           for (h=0; h<=nhstepm; h++){             for (h=0; h<=nhstepm; h++){
             fprintf(ficrespij,"%d %.0f %.0f",k,agedeb, agedeb+ h*hstepm/YEARM*stepm );              fprintf(ficrespij,"%d %.0f %.0f",k,agedeb, agedeb+ h*hstepm/YEARM*stepm );
             for(i=1; i<=nlstate;i++)              for(i=1; i<=nlstate;i++)
               for(j=1; j<=nlstate+ndeath;j++)                for(j=1; j<=nlstate+ndeath;j++)
                 fprintf(ficrespij," %.5f", p3mat[i][j][h]);                  fprintf(ficrespij," %.5f", p3mat[i][j][h]);
             fprintf(ficrespij,"\n");              fprintf(ficrespij,"\n");
           }               }
           free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);            free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           fprintf(ficrespij,"\n");            fprintf(ficrespij,"\n");
         }          }
     }      }
   }    }
   
   /* varprob(fileres, matcov, p, delti, nlstate, (int) bage, (int) fage,k);*/    varprob(fileres, matcov, p, delti, nlstate, (int) bage, (int) fage,k,Tvar,nbcode, ncodemax);
   
   fclose(ficrespij);    fclose(ficrespij);
   
   if(stepm == 1) {  
   /*---------- Forecasting ------------------*/  
   calagedate=(anproj1+mproj1/12.+jproj1/365.-dateintmean)*YEARM;  
   
    
    
   prevalence(agemin, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax,mint,anint,dateprev1,dateprev2, calagedate);  
   
      /*---------- Forecasting ------------------*/
   strcpy(fileresf,"f");    if((stepm == 1) && (strcmp(model,".")==0)){
   strcat(fileresf,fileres);      prevforecast(fileres, anproj1,mproj1,jproj1, agemin,agemax, dateprev1, dateprev2,mobilav, agedeb, fage, popforecast, popfile, anproj2,p, i1);
   if((ficresf=fopen(fileresf,"w"))==NULL) {      if (popforecast==1) populforecast(fileres, anpyram,mpyram,jpyram, agemin,agemax, dateprev1, dateprev2,mobilav, agedeb, fage, popforecast, popfile, anpyram1,p, i1);
     printf("Problem with forecast resultfile: %s\n", fileresf);goto end;    }
   }  
   printf("Computing forecasting: result on file '%s' \n", fileresf);  
    
   free_matrix(mint,1,maxwav,1,n);  
   free_matrix(anint,1,maxwav,1,n);  
   
   if (cptcoveff==0) ncodemax[cptcoveff]=1;  
   
   if (mobilav==1) {  
     mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);  
     movingaverage(agedeb, fage, agemin, mobaverage);  
   }  
   
   stepsize=(int) (stepm+YEARM-1)/YEARM;  
   if (stepm<=12) stepsize=1;  
    
   agelim=AGESUP;  
    
   hstepm=1;  
   hstepm=hstepm/stepm;  
   yp1=modf(dateintmean,&yp);  
   anprojmean=yp;  
   yp2=modf((yp1*12),&yp);  
   mprojmean=yp;  
   yp1=modf((yp2*30.5),&yp);  
   jprojmean=yp;  
   if(jprojmean==0) jprojmean=1;  
   if(mprojmean==0) jprojmean=1;  
    
   fprintf(ficresf,"# Estimated date of observed prevalence: %.lf/%.lf/%.lf ",jprojmean,mprojmean,anprojmean);  
    
   if (popforecast==1) {  
     if((ficpop=fopen(popfile,"r"))==NULL)    {  
       printf("Problem with population file : %s\n",popfile);goto end;  
     }  
     popage=ivector(0,AGESUP);  
     popeffectif=vector(0,AGESUP);  
     popcount=vector(0,AGESUP);  
      
     i=1;    
     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF)  
       {  
         i=i+1;  
       }  
     imx=i;  
      
     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i];  
   }  
    
   for(cptcov=1;cptcov<=i1;cptcov++){  
     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){  
       k=k+1;  
       fprintf(ficresf,"\n#******");  
       for(j=1;j<=cptcoveff;j++) {  
         fprintf(ficresf," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);  
       }  
       fprintf(ficresf,"******\n");  
       fprintf(ficresf,"# StartingAge FinalAge");  
       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficresf," P.%d",j);  
       if (popforecast==1)  fprintf(ficresf," [Population]");  
        
       for (cpt=0; cpt<=(anproj2-anproj1);cpt++) {  
         fprintf(ficresf,"\n");  
         fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+cpt);    
          
         for (agedeb=(fage-((int)calagedate %12/12.)); agedeb>=(agemin-((int)calagedate %12)/12.); agedeb--){  
           nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  
           nhstepm = nhstepm/hstepm;  
            
           p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);  
           oldm=oldms;savm=savms;  
           hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);    
          
           for (h=0; h<=nhstepm; h++){  
             if (h==(int) (calagedate+YEARM*cpt)) {  
               fprintf(ficresf,"\n %.f ",agedeb+h*hstepm/YEARM*stepm);  
             }  
             for(j=1; j<=nlstate+ndeath;j++) {  
               kk1=0.;kk2=0;  
               for(i=1; i<=nlstate;i++) {                
                 if (mobilav==1)  
                   kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod];  
                 else {  
                   kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod];  
                 }  
                 if (popforecast==1) kk2=kk1*popeffectif[(int)agedeb];  
               }  
               if (h==(int)(calagedate+12*cpt)){  
                 fprintf(ficresf," %.3f", kk1);  
                
                 if (popforecast==1) fprintf(ficresf," [%.f]", kk2);  
               }  
             }  
           }  
           free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);  
         }  
       }  
     }  
   }  
          
   if (mobilav==1) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);  
   
   if (popforecast==1) {  
     free_ivector(popage,0,AGESUP);  
     free_vector(popeffectif,0,AGESUP);  
     free_vector(popcount,0,AGESUP);  
   }  
    
   free_imatrix(s,1,maxwav+1,1,n);  
   free_vector(weight,1,n);  
   fclose(ficresf);  
   }  
   
   /* End forecasting */  
   else{    else{
     erreur=108;      erreur=108;
     printf("Error %d!! You can only forecast the prevalences if the optimization\n  has been performed with stepm = 1 (month) instead of %d\n", erreur, stepm);      printf("Warning %d!! You can only forecast the prevalences if the optimization\n  has been performed with stepm = 1 (month) instead of %d or model=. instead of '%s'\n", erreur, stepm, model);
   }    }
     
    
   /*---------- Health expectancies and variances ------------*/    /*---------- Health expectancies and variances ------------*/
   
   strcpy(filerest,"t");    strcpy(filerest,"t");
Line 3058  fprintf(ficres,"popforecast=%d popfile=% Line 3426  fprintf(ficres,"popforecast=%d popfile=%
     printf("Problem with variance resultfile: %s\n", fileresv);exit(0);      printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
   }    }
   printf("Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);    printf("Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);
     calagedate=-1;
   prevalence(ageminpar, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax,mint,anint,dateprev1,dateprev2, calagedate);
   
   k=0;    k=0;
   for(cptcov=1;cptcov<=i1;cptcov++){    for(cptcov=1;cptcov<=i1;cptcov++){
Line 3070  fprintf(ficres,"popforecast=%d popfile=% Line 3440  fprintf(ficres,"popforecast=%d popfile=%
   
       fprintf(ficreseij,"\n#****** ");        fprintf(ficreseij,"\n#****** ");
       for(j=1;j<=cptcoveff;j++)        for(j=1;j<=cptcoveff;j++)
         fprintf(ficreseij,"V%d=%d ",j,nbcode[j][codtab[k][j]]);          fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
       fprintf(ficreseij,"******\n");        fprintf(ficreseij,"******\n");
   
       fprintf(ficresvij,"\n#****** ");        fprintf(ficresvij,"\n#****** ");
       for(j=1;j<=cptcoveff;j++)        for(j=1;j<=cptcoveff;j++)
         fprintf(ficresvij,"V%d=%d ",j,nbcode[j][codtab[k][j]]);          fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
       fprintf(ficresvij,"******\n");        fprintf(ficresvij,"******\n");
   
       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);        eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
       oldm=oldms;savm=savms;        oldm=oldms;savm=savms;
       evsij(fileres, eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k);          evsij(fileres, eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov);  
    
       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);        vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
       oldm=oldms;savm=savms;        oldm=oldms;savm=savms;
        varevsij(fileres, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k);         varevsij(fileres, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k, estepm);
         
   
     
Line 3091  fprintf(ficres,"popforecast=%d popfile=% Line 3462  fprintf(ficres,"popforecast=%d popfile=%
       for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
       fprintf(ficrest,"\n");        fprintf(ficrest,"\n");
   
       hf=1;  
       if (stepm >= YEARM) hf=stepm/YEARM;  
       epj=vector(1,nlstate+1);        epj=vector(1,nlstate+1);
       for(age=bage; age <=fage ;age++){        for(age=bage; age <=fage ;age++){
         prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);          prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);
Line 3101  fprintf(ficres,"popforecast=%d popfile=% Line 3470  fprintf(ficres,"popforecast=%d popfile=%
             prlim[i][i]=probs[(int)age][i][k];              prlim[i][i]=probs[(int)age][i][k];
         }          }
                 
         fprintf(ficrest," %.0f",age);          fprintf(ficrest," %4.0f",age);
         for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
           for(i=1, epj[j]=0.;i <=nlstate;i++) {            for(i=1, epj[j]=0.;i <=nlstate;i++) {
             epj[j] += prlim[i][i]*hf*eij[i][j][(int)age];              epj[j] += prlim[i][i]*eij[i][j][(int)age];
               /*  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
           }            }
           epj[nlstate+1] +=epj[j];            epj[nlstate+1] +=epj[j];
         }          }
   
         for(i=1, vepp=0.;i <=nlstate;i++)          for(i=1, vepp=0.;i <=nlstate;i++)
           for(j=1;j <=nlstate;j++)            for(j=1;j <=nlstate;j++)
             vepp += vareij[i][j][(int)age];              vepp += vareij[i][j][(int)age];
         fprintf(ficrest," %.2f (%.2f)", epj[nlstate+1],hf*sqrt(vepp));          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
         for(j=1;j <=nlstate;j++){          for(j=1;j <=nlstate;j++){
           fprintf(ficrest," %.2f (%.2f)", epj[j],hf*sqrt(vareij[j][j][(int)age]));            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
         }          }
         fprintf(ficrest,"\n");          fprintf(ficrest,"\n");
       }        }
     }      }
   }    }
          free_matrix(mint,1,maxwav,1,n);
              free_matrix(anint,1,maxwav,1,n); free_imatrix(s,1,maxwav+1,1,n);
       free_vector(weight,1,n);
     fclose(ficreseij);
  fclose(ficreseij);    fclose(ficresvij);
  fclose(ficresvij);  
   fclose(ficrest);    fclose(ficrest);
   fclose(ficpar);    fclose(ficpar);
   free_vector(epj,1,nlstate+1);    free_vector(epj,1,nlstate+1);
   /*  scanf("%d ",i); */  
     
   /*------- Variance limit prevalence------*/      /*------- Variance limit prevalence------*/  
   
 strcpy(fileresvpl,"vpl");    strcpy(fileresvpl,"vpl");
   strcat(fileresvpl,fileres);    strcat(fileresvpl,fileres);
   if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {    if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
     printf("Problem with variance prev lim resultfile: %s\n", fileresvpl);      printf("Problem with variance prev lim resultfile: %s\n", fileresvpl);
Line 3140  strcpy(fileresvpl,"vpl"); Line 3509  strcpy(fileresvpl,"vpl");
   }    }
   printf("Computing Variance-covariance of Prevalence limit: file '%s' \n", fileresvpl);    printf("Computing Variance-covariance of Prevalence limit: file '%s' \n", fileresvpl);
   
  k=0;    k=0;
  for(cptcov=1;cptcov<=i1;cptcov++){    for(cptcov=1;cptcov<=i1;cptcov++){
    for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){      for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
      k=k+1;        k=k+1;
      fprintf(ficresvpl,"\n#****** ");        fprintf(ficresvpl,"\n#****** ");
      for(j=1;j<=cptcoveff;j++)        for(j=1;j<=cptcoveff;j++)
        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);          fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
      fprintf(ficresvpl,"******\n");        fprintf(ficresvpl,"******\n");
             
      varpl=matrix(1,nlstate,(int) bage, (int) fage);        varpl=matrix(1,nlstate,(int) bage, (int) fage);
      oldm=oldms;savm=savms;        oldm=oldms;savm=savms;
      varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k);       varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k);
    }      }
  }   }
   
   fclose(ficresvpl);    fclose(ficresvpl);
Line 3175  strcpy(fileresvpl,"vpl"); Line 3544  strcpy(fileresvpl,"vpl");
   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);    free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
   
   if(erreur >0)    if(erreur >0)
     printf("End of Imach with error %d\n",erreur);      printf("End of Imach with error or warning %d\n",erreur);
   else   printf("End of Imach\n");    else   printf("End of Imach\n");
   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */    /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
     
Line 3185  strcpy(fileresvpl,"vpl"); Line 3554  strcpy(fileresvpl,"vpl");
   
   
  end:   end:
 #ifdef windows  
   /* chdir(pathcd);*/    /* chdir(pathcd);*/
 #endif  
  /*system("wgnuplot graph.plt");*/   /*system("wgnuplot graph.plt");*/
  /*system("../gp37mgw/wgnuplot graph.plt");*/   /*system("../gp37mgw/wgnuplot graph.plt");*/
  /*system("cd ../gp37mgw");*/   /*system("cd ../gp37mgw");*/
Line 3197  strcpy(fileresvpl,"vpl"); Line 3564  strcpy(fileresvpl,"vpl");
  strcat(plotcmd,optionfilegnuplot);   strcat(plotcmd,optionfilegnuplot);
  system(plotcmd);   system(plotcmd);
   
 #ifdef windows   /*#ifdef windows*/
   while (z[0] != 'q') {    while (z[0] != 'q') {
     chdir(path);      /* chdir(path); */
     printf("\nType e to edit output files, c to start again, and q for exiting: ");      printf("\nType e to edit output files, g to graph again, c to start again, and q for exiting: ");
     scanf("%s",z);      scanf("%s",z);
     if (z[0] == 'c') system("./imach");      if (z[0] == 'c') system("./imach");
     else if (z[0] == 'e') {      else if (z[0] == 'e') system(optionfilehtm);
       chdir(path);      else if (z[0] == 'g') system(plotcmd);
       system(optionfilehtm);  
     }  
     else if (z[0] == 'q') exit(0);      else if (z[0] == 'q') exit(0);
   }    }
 #endif    /*#endif */
 }  }
   
   
Removed from v.1.26  
changed lines
  Added in v.1.41.2.2

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