Diff for /imach/src/imach.c between versions 1.41.2.1 and 1.78

version 1.41.2.1, 2003/06/12 10:43:20 version 1.78, 2003/05/27 17:26:53
Line 1 Line 1
 /* $Id$  /* $Id$
    Interpolated Markov Chain     Interpolated Markov Chain
   
   Short summary of the programme:    Short summary of the programme:
      
   This program computes Healthy Life Expectancies from    This program computes Healthy Life Expectancies from
   cross-longitudinal data. Cross-longitudinal data consist in: -1- a    cross-longitudinal data. Cross-longitudinal data consist in: -1- a
   first survey ("cross") where individuals from different ages are    first survey ("cross") where individuals from different ages are
   interviewed on their health status or degree of disability (in the    interviewed on their health status or degree of disability (in the
   case of a health survey which is our main interest) -2- at least a    case of a health survey which is our main interest) -2- at least a
   second wave of interviews ("longitudinal") which measure each change    second wave of interviews ("longitudinal") which measure each change
   (if any) in individual health status.  Health expectancies are    (if any) in individual health status.  Health expectancies are
   computed from the time spent in each health state according to a    computed from the time spent in each health state according to a
   model. More health states you consider, more time is necessary to reach the    model. More health states you consider, more time is necessary to reach the
   Maximum Likelihood of the parameters involved in the model.  The    Maximum Likelihood of the parameters involved in the model.  The
   simplest model is the multinomial logistic model where pij is the    simplest model is the multinomial logistic model where pij is the
   probability to be observed in state j at the second wave    probability to be observed in state j at the second wave
   conditional to be observed in state i at the first wave. Therefore    conditional to be observed in state i at the first wave. Therefore
   the model is: log(pij/pii)= aij + bij*age+ cij*sex + etc , where    the model is: log(pij/pii)= aij + bij*age+ cij*sex + etc , where
   'age' is age and 'sex' is a covariate. If you want to have a more    'age' is age and 'sex' is a covariate. If you want to have a more
   complex model than "constant and age", you should modify the program    complex model than "constant and age", you should modify the program
   where the markup *Covariates have to be included here again* invites    where the markup *Covariates have to be included here again* invites
   you to do it.  More covariates you add, slower the    you to do it.  More covariates you add, slower the
   convergence.    convergence.
   
   The advantage of this computer programme, compared to a simple    The advantage of this computer programme, compared to a simple
   multinomial logistic model, is clear when the delay between waves is not    multinomial logistic model, is clear when the delay between waves is not
   identical for each individual. Also, if a individual missed an    identical for each individual. Also, if a individual missed an
   intermediate interview, the information is lost, but taken into    intermediate interview, the information is lost, but taken into
   account using an interpolation or extrapolation.      account using an interpolation or extrapolation.  
   
   hPijx is the probability to be observed in state i at age x+h    hPijx is the probability to be observed in state i at age x+h
   conditional to the observed state i at age x. The delay 'h' can be    conditional to the observed state i at age x. The delay 'h' can be
   split into an exact number (nh*stepm) of unobserved intermediate    split into an exact number (nh*stepm) of unobserved intermediate
   states. This elementary transition (by month or quarter trimester,    states. This elementary transition (by month, quarter,
   semester or year) is model as a multinomial logistic.  The hPx    semester or year) is modelled as a multinomial logistic.  The hPx
   matrix is simply the matrix product of nh*stepm elementary matrices    matrix is simply the matrix product of nh*stepm elementary matrices
   and the contribution of each individual to the likelihood is simply    and the contribution of each individual to the likelihood is simply
   hPijx.    hPijx.
   
   Also this programme outputs the covariance matrix of the parameters but also    Also this programme outputs the covariance matrix of the parameters but also
   of the life expectancies. It also computes the prevalence limits.    of the life expectancies. It also computes the stable prevalence. 
      
   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).    Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
            Institut national d'études démographiques, Paris.             Institut national d'études démographiques, Paris.
   This software have been partly granted by Euro-REVES, a concerted action    This software have been partly granted by Euro-REVES, a concerted action
   from the European Union.    from the European Union.
   It is copyrighted identically to a GNU software product, ie programme and    It is copyrighted identically to a GNU software product, ie programme and
   software can be distributed freely for non commercial use. Latest version    software can be distributed freely for non commercial use. Latest version
   can be accessed at http://euroreves.ined.fr/imach .    can be accessed at http://euroreves.ined.fr/imach .
   **********************************************************************/  
      Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
 #include <math.h>    or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
 #include <stdio.h>    
 #include <stdlib.h>    **********************************************************************/
 #include <unistd.h>  /*
     main
 #define MAXLINE 256    read parameterfile
 #define GNUPLOTPROGRAM "wgnuplot"    read datafile
 /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/    concatwav
 #define FILENAMELENGTH 80    if (mle >= 1)
 /*#define DEBUG*/      mlikeli
     print results files
 /*#define windows*/    if mle==1 
 #define GLOCK_ERROR_NOPATH              -1      /* empty path */       computes hessian
 #define GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */    read end of parameter file: agemin, agemax, bage, fage, estepm
         begin-prev-date,...
 #define MAXPARM 30 /* Maximum number of parameters for the optimization */    open gnuplot file
 #define NPARMAX 64 /* (nlstate+ndeath-1)*nlstate*ncovmodel */    open html file
     stable prevalence
 #define NINTERVMAX 8     for age prevalim()
 #define NLSTATEMAX 8 /* Maximum number of live states (for func) */    h Pij x
 #define NDEATHMAX 8 /* Maximum number of dead states (for func) */    variance of p varprob
 #define NCOVMAX 8 /* Maximum number of covariates */    forecasting if prevfcast==1 prevforecast call prevalence()
 #define MAXN 20000    health expectancies
 #define YEARM 12. /* Number of months per year */    Variance-covariance of DFLE
 #define AGESUP 130    prevalence()
 #define AGEBASE 40     movingaverage()
     varevsij() 
     if popbased==1 varevsij(,popbased)
 int erreur; /* Error number */    total life expectancies
 int nvar;    Variance of stable prevalence
 int cptcovn, cptcovage=0, cptcoveff=0,cptcov;   end
 int npar=NPARMAX;  */
 int nlstate=2; /* Number of live states */  
 int ndeath=1; /* Number of dead states */  
 int ncovmodel, ncovcol;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */  
 int popbased=0;   
   #include <math.h>
 int *wav; /* Number of waves for this individuual 0 is possible */  #include <stdio.h>
 int maxwav; /* Maxim number of waves */  #include <stdlib.h>
 int jmin, jmax; /* min, max spacing between 2 waves */  #include <unistd.h>
 int mle, weightopt;  
 int **mw; /* mw[mi][i] is number of the mi wave for this individual */  #define MAXLINE 256
 int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */  #define GNUPLOTPROGRAM "gnuplot"
 double jmean; /* Mean space between 2 waves */  /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
 double **oldm, **newm, **savm; /* Working pointers to matrices */  #define FILENAMELENGTH 80
 double **oldms, **newms, **savms; /* Fixed working pointers to matrices */  /*#define DEBUG*/
 FILE *fic,*ficpar, *ficparo,*ficres,  *ficrespl, *ficrespij, *ficrest,*ficresf,*ficrespop;  #define windows
 FILE *ficgp,*ficresprob,*ficpop;  #define GLOCK_ERROR_NOPATH              -1      /* empty path */
 FILE *ficreseij;  #define GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
   char filerese[FILENAMELENGTH];  
  FILE  *ficresvij;  #define MAXPARM 30 /* Maximum number of parameters for the optimization */
   char fileresv[FILENAMELENGTH];  #define NPARMAX 64 /* (nlstate+ndeath-1)*nlstate*ncovmodel */
  FILE  *ficresvpl;  
   char fileresvpl[FILENAMELENGTH];  #define NINTERVMAX 8
   #define NLSTATEMAX 8 /* Maximum number of live states (for func) */
 #define NR_END 1  #define NDEATHMAX 8 /* Maximum number of dead states (for func) */
 #define FREE_ARG char*  #define NCOVMAX 8 /* Maximum number of covariates */
 #define FTOL 1.0e-10  #define MAXN 20000
   #define YEARM 12. /* Number of months per year */
 #define NRANSI  #define AGESUP 130
 #define ITMAX 200  #define AGEBASE 40
   #ifdef windows
 #define TOL 2.0e-4  #define DIRSEPARATOR '\\'
   #define ODIRSEPARATOR '/'
 #define CGOLD 0.3819660  #else
 #define ZEPS 1.0e-10  #define DIRSEPARATOR '/'
 #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d);  #define ODIRSEPARATOR '\\'
   #endif
 #define GOLD 1.618034  
 #define GLIMIT 100.0  char version[80]="Imach version 0.95a, May 2003, INED-EUROREVES ";
 #define TINY 1.0e-20  int erreur; /* Error number */
   int nvar;
 static double maxarg1,maxarg2;  int cptcovn=0, cptcovage=0, cptcoveff=0,cptcov;
 #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))  int npar=NPARMAX;
 #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))  int nlstate=2; /* Number of live states */
    int ndeath=1; /* Number of dead states */
 #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))  int ncovmodel, ncovcol;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
 #define rint(a) floor(a+0.5)  int popbased=0;
   
 static double sqrarg;  int *wav; /* Number of waves for this individuual 0 is possible */
 #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)  int maxwav; /* Maxim number of waves */
 #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;}  int jmin, jmax; /* min, max spacing between 2 waves */
   int mle, weightopt;
 int imx;  int **mw; /* mw[mi][i] is number of the mi wave for this individual */
 int stepm;  int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
 /* Stepm, step in month: minimum step interpolation*/  int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
              * wave mi and wave mi+1 is not an exact multiple of stepm. */
 int estepm;  double jmean; /* Mean space between 2 waves */
 /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/  double **oldm, **newm, **savm; /* Working pointers to matrices */
   double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
 int m,nb;  FILE *fic,*ficpar, *ficparo,*ficres,  *ficrespl, *ficrespij, *ficrest,*ficresf,*ficrespop;
 int *num, firstpass=0, lastpass=4,*cod, *ncodemax, *Tage;  FILE *ficlog, *ficrespow;
 double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;  FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
 double **pmmij, ***probs, ***mobaverage;  FILE *ficresprobmorprev;
 double dateintmean=0;  FILE *fichtm; /* Html File */
   FILE *ficreseij;
 double *weight;  char filerese[FILENAMELENGTH];
 int **s; /* Status */  FILE  *ficresvij;
 double *agedc, **covar, idx;  char fileresv[FILENAMELENGTH];
 int **nbcode, *Tcode, *Tvar, **codtab, **Tvard, *Tprod, cptcovprod, *Tvaraff;  FILE  *ficresvpl;
   char fileresvpl[FILENAMELENGTH];
 double ftol=FTOL; /* Tolerance for computing Max Likelihood */  char title[MAXLINE];
 double ftolhess; /* Tolerance for computing hessian */  char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH];
   char optionfilext[10], optionfilefiname[FILENAMELENGTH], plotcmd[FILENAMELENGTH];
 /**************** split *************************/  
 static  int split( char *path, char *dirc, char *name, char *ext, char *finame )  char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
 {  char filelog[FILENAMELENGTH]; /* Log file */
    char *s;                             /* pointer */  char filerest[FILENAMELENGTH];
    int  l1, l2;                         /* length counters */  char fileregp[FILENAMELENGTH];
   char popfile[FILENAMELENGTH];
    l1 = strlen( path );                 /* length of path */  
    if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );  char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH];
 #ifdef windows  
    s = strrchr( path, '\\' );           /* find last / */  #define NR_END 1
 #else  #define FREE_ARG char*
    s = strrchr( path, '/' );            /* find last / */  #define FTOL 1.0e-10
 #endif  
    if ( s == NULL ) {                   /* no directory, so use current */  #define NRANSI 
 #if     defined(__bsd__)                /* get current working directory */  #define ITMAX 200 
       extern char       *getwd( );  
   #define TOL 2.0e-4 
       if ( getwd( dirc ) == NULL ) {  
 #else  #define CGOLD 0.3819660 
       extern char       *getcwd( );  #define ZEPS 1.0e-10 
   #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
       if ( getcwd( dirc, FILENAME_MAX ) == NULL ) {  
 #endif  #define GOLD 1.618034 
          return( GLOCK_ERROR_GETCWD );  #define GLIMIT 100.0 
       }  #define TINY 1.0e-20 
       strcpy( name, path );             /* we've got it */  
    } else {                             /* strip direcotry from path */  static double maxarg1,maxarg2;
       s++;                              /* after this, the filename */  #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
       l2 = strlen( s );                 /* length of filename */  #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
       if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );    
       strcpy( name, s );                /* save file name */  #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
       strncpy( dirc, path, l1 - l2 );   /* now the directory */  #define rint(a) floor(a+0.5)
       dirc[l1-l2] = 0;                  /* add zero */  
    }  static double sqrarg;
    l1 = strlen( dirc );                 /* length of directory */  #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
 #ifdef windows  #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
    if ( dirc[l1-1] != '\\' ) { dirc[l1] = '\\'; dirc[l1+1] = 0; }  
 #else  int imx; 
    if ( dirc[l1-1] != '/' ) { dirc[l1] = '/'; dirc[l1+1] = 0; }  int stepm;
 #endif  /* Stepm, step in month: minimum step interpolation*/
    s = strrchr( name, '.' );            /* find last / */  
    s++;  int estepm;
    strcpy(ext,s);                       /* save extension */  /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
    l1= strlen( name);  
    l2= strlen( s)+1;  int m,nb;
    strncpy( finame, name, l1-l2);  int *num, firstpass=0, lastpass=4,*cod, *ncodemax, *Tage;
    finame[l1-l2]= 0;  double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
    return( 0 );                         /* we're done */  double **pmmij, ***probs;
 }  double dateintmean=0;
   
   double *weight;
 /******************************************/  int **s; /* Status */
   double *agedc, **covar, idx;
 void replace(char *s, char*t)  int **nbcode, *Tcode, *Tvar, **codtab, **Tvard, *Tprod, cptcovprod, *Tvaraff;
 {  
   int i;  double ftol=FTOL; /* Tolerance for computing Max Likelihood */
   int lg=20;  double ftolhess; /* Tolerance for computing hessian */
   i=0;  
   lg=strlen(t);  /**************** split *************************/
   for(i=0; i<= lg; i++) {  static  int split( char *path, char *dirc, char *name, char *ext, char *finame )
     (s[i] = t[i]);  {
     if (t[i]== '\\') s[i]='/';    char  *ss;                            /* pointer */
   }    int   l1, l2;                         /* length counters */
 }  
     l1 = strlen(path );                   /* length of path */
 int nbocc(char *s, char occ)    if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
 {    ss= strrchr( path, DIRSEPARATOR );            /* find last / */
   int i,j=0;    if ( ss == NULL ) {                   /* no directory, so use current */
   int lg=20;      /*if(strrchr(path, ODIRSEPARATOR )==NULL)
   i=0;        printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
   lg=strlen(s);      /* get current working directory */
   for(i=0; i<= lg; i++) {      /*    extern  char* getcwd ( char *buf , int len);*/
   if  (s[i] == occ ) j++;      if ( getcwd( dirc, FILENAME_MAX ) == NULL ) {
   }        return( GLOCK_ERROR_GETCWD );
   return j;      }
 }      strcpy( name, path );               /* we've got it */
     } else {                              /* strip direcotry from path */
 void cutv(char *u,char *v, char*t, char occ)      ss++;                               /* after this, the filename */
 {      l2 = strlen( ss );                  /* length of filename */
   int i,lg,j,p=0;      if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
   i=0;      strcpy( name, ss );         /* save file name */
   for(j=0; j<=strlen(t)-1; j++) {      strncpy( dirc, path, l1 - l2 );     /* now the directory */
     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1;      dirc[l1-l2] = 0;                    /* add zero */
   }    }
     l1 = strlen( dirc );                  /* length of directory */
   lg=strlen(t);  #ifdef windows
   for(j=0; j<p; j++) {    if ( dirc[l1-1] != '\\' ) { dirc[l1] = '\\'; dirc[l1+1] = 0; }
     (u[j] = t[j]);  #else
   }    if ( dirc[l1-1] != '/' ) { dirc[l1] = '/'; dirc[l1+1] = 0; }
      u[p]='\0';  #endif
     ss = strrchr( name, '.' );            /* find last / */
    for(j=0; j<= lg; j++) {    ss++;
     if (j>=(p+1))(v[j-p-1] = t[j]);    strcpy(ext,ss);                       /* save extension */
   }    l1= strlen( name);
 }    l2= strlen(ss)+1;
     strncpy( finame, name, l1-l2);
 /********************** nrerror ********************/    finame[l1-l2]= 0;
     return( 0 );                          /* we're done */
 void nrerror(char error_text[])  }
 {  
   fprintf(stderr,"ERREUR ...\n");  
   fprintf(stderr,"%s\n",error_text);  /******************************************/
   exit(1);  
 }  void replace(char *s, char*t)
 /*********************** vector *******************/  {
 double *vector(int nl, int nh)    int i;
 {    int lg=20;
   double *v;    i=0;
   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));    lg=strlen(t);
   if (!v) nrerror("allocation failure in vector");    for(i=0; i<= lg; i++) {
   return v-nl+NR_END;      (s[i] = t[i]);
 }      if (t[i]== '\\') s[i]='/';
     }
 /************************ free vector ******************/  }
 void free_vector(double*v, int nl, int nh)  
 {  int nbocc(char *s, char occ)
   free((FREE_ARG)(v+nl-NR_END));  {
 }    int i,j=0;
     int lg=20;
 /************************ivector *******************************/    i=0;
 int *ivector(long nl,long nh)    lg=strlen(s);
 {    for(i=0; i<= lg; i++) {
   int *v;    if  (s[i] == occ ) j++;
   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));    }
   if (!v) nrerror("allocation failure in ivector");    return j;
   return v-nl+NR_END;  }
 }  
   void cutv(char *u,char *v, char*t, char occ)
 /******************free ivector **************************/  {
 void free_ivector(int *v, long nl, long nh)    /* cuts string t into u and v where u is ended by char occ excluding it
 {       and v is after occ excluding it too : ex cutv(u,v,"abcdef2ghi2j",2)
   free((FREE_ARG)(v+nl-NR_END));       gives u="abcedf" and v="ghi2j" */
 }    int i,lg,j,p=0;
     i=0;
 /******************* imatrix *******************************/    for(j=0; j<=strlen(t)-1; j++) {
 int **imatrix(long nrl, long nrh, long ncl, long nch)      if((t[j]!= occ) && (t[j+1]== occ)) p=j+1;
      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */    }
 {  
   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1;    lg=strlen(t);
   int **m;    for(j=0; j<p; j++) {
        (u[j] = t[j]);
   /* allocate pointers to rows */    }
   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*)));       u[p]='\0';
   if (!m) nrerror("allocation failure 1 in matrix()");  
   m += NR_END;     for(j=0; j<= lg; j++) {
   m -= nrl;      if (j>=(p+1))(v[j-p-1] = t[j]);
      }
    }
   /* allocate rows and set pointers to them */  
   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int)));  /********************** nrerror ********************/
   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");  
   m[nrl] += NR_END;  void nrerror(char error_text[])
   m[nrl] -= ncl;  {
      fprintf(stderr,"ERREUR ...\n");
   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol;    fprintf(stderr,"%s\n",error_text);
      exit(EXIT_FAILURE);
   /* return pointer to array of pointers to rows */  }
   return m;  /*********************** vector *******************/
 }  double *vector(int nl, int nh)
   {
 /****************** free_imatrix *************************/    double *v;
 void free_imatrix(m,nrl,nrh,ncl,nch)    v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
       int **m;    if (!v) nrerror("allocation failure in vector");
       long nch,ncl,nrh,nrl;    return v-nl+NR_END;
      /* free an int matrix allocated by imatrix() */  }
 {  
   free((FREE_ARG) (m[nrl]+ncl-NR_END));  /************************ free vector ******************/
   free((FREE_ARG) (m+nrl-NR_END));  void free_vector(double*v, int nl, int nh)
 }  {
     free((FREE_ARG)(v+nl-NR_END));
 /******************* matrix *******************************/  }
 double **matrix(long nrl, long nrh, long ncl, long nch)  
 {  /************************ivector *******************************/
   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;  char *cvector(long nl,long nh)
   double **m;  {
     char *v;
   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));    v=(char *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(char)));
   if (!m) nrerror("allocation failure 1 in matrix()");    if (!v) nrerror("allocation failure in cvector");
   m += NR_END;    return v-nl+NR_END;
   m -= nrl;  }
   
   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));  /******************free ivector **************************/
   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");  void free_cvector(char *v, long nl, long nh)
   m[nrl] += NR_END;  {
   m[nrl] -= ncl;    free((FREE_ARG)(v+nl-NR_END));
   }
   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;  
   return m;  /************************ivector *******************************/
 }  int *ivector(long nl,long nh)
   {
 /*************************free matrix ************************/    int *v;
 void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)    v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
 {    if (!v) nrerror("allocation failure in ivector");
   free((FREE_ARG)(m[nrl]+ncl-NR_END));    return v-nl+NR_END;
   free((FREE_ARG)(m+nrl-NR_END));  }
 }  
   /******************free ivector **************************/
 /******************* ma3x *******************************/  void free_ivector(int *v, long nl, long nh)
 double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)  {
 {    free((FREE_ARG)(v+nl-NR_END));
   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;  }
   double ***m;  
   /******************* imatrix *******************************/
   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));  int **imatrix(long nrl, long nrh, long ncl, long nch) 
   if (!m) nrerror("allocation failure 1 in matrix()");       /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
   m += NR_END;  { 
   m -= nrl;    long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
     int **m; 
   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));    
   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");    /* allocate pointers to rows */ 
   m[nrl] += NR_END;    m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
   m[nrl] -= ncl;    if (!m) nrerror("allocation failure 1 in matrix()"); 
     m += NR_END; 
   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;    m -= nrl; 
     
   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));    
   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");    /* allocate rows and set pointers to them */ 
   m[nrl][ncl] += NR_END;    m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
   m[nrl][ncl] -= nll;    if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
   for (j=ncl+1; j<=nch; j++)    m[nrl] += NR_END; 
     m[nrl][j]=m[nrl][j-1]+nlay;    m[nrl] -= ncl; 
      
   for (i=nrl+1; i<=nrh; i++) {    for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;    
     for (j=ncl+1; j<=nch; j++)    /* return pointer to array of pointers to rows */ 
       m[i][j]=m[i][j-1]+nlay;    return m; 
   }  } 
   return m;  
 }  /****************** free_imatrix *************************/
   void free_imatrix(m,nrl,nrh,ncl,nch)
 /*************************free ma3x ************************/        int **m;
 void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)        long nch,ncl,nrh,nrl; 
 {       /* free an int matrix allocated by imatrix() */ 
   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));  { 
   free((FREE_ARG)(m[nrl]+ncl-NR_END));    free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
   free((FREE_ARG)(m+nrl-NR_END));    free((FREE_ARG) (m+nrl-NR_END)); 
 }  } 
   
 /***************** f1dim *************************/  /******************* matrix *******************************/
 extern int ncom;  double **matrix(long nrl, long nrh, long ncl, long nch)
 extern double *pcom,*xicom;  {
 extern double (*nrfunc)(double []);    long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
      double **m;
 double f1dim(double x)  
 {    m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
   int j;    if (!m) nrerror("allocation failure 1 in matrix()");
   double f;    m += NR_END;
   double *xt;    m -= nrl;
    
   xt=vector(1,ncom);    m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j];    if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
   f=(*nrfunc)(xt);    m[nrl] += NR_END;
   free_vector(xt,1,ncom);    m[nrl] -= ncl;
   return f;  
 }    for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
     return m;
 /*****************brent *************************/    /* print *(*(m+1)+70) ou print m[1][70]; print m+1 or print &(m[1]) 
 double brent(double ax, double bx, double cx, double (*f)(double), double tol,  double *xmin)     */
 {  }
   int iter;  
   double a,b,d,etemp;  /*************************free matrix ************************/
   double fu,fv,fw,fx;  void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
   double ftemp;  {
   double p,q,r,tol1,tol2,u,v,w,x,xm;    free((FREE_ARG)(m[nrl]+ncl-NR_END));
   double e=0.0;    free((FREE_ARG)(m+nrl-NR_END));
    }
   a=(ax < cx ? ax : cx);  
   b=(ax > cx ? ax : cx);  /******************* ma3x *******************************/
   x=w=v=bx;  double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
   fw=fv=fx=(*f)(x);  {
   for (iter=1;iter<=ITMAX;iter++) {    long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
     xm=0.5*(a+b);    double ***m;
     tol2=2.0*(tol1=tol*fabs(x)+ZEPS);  
     /*          if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/    m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
     printf(".");fflush(stdout);    if (!m) nrerror("allocation failure 1 in matrix()");
 #ifdef DEBUG    m += NR_END;
     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);    m -= nrl;
     /*          if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */  
 #endif    m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
     if (fabs(x-xm) <= (tol2-0.5*(b-a))){    if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
       *xmin=x;    m[nrl] += NR_END;
       return fx;    m[nrl] -= ncl;
     }  
     ftemp=fu;    for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
     if (fabs(e) > tol1) {  
       r=(x-w)*(fx-fv);    m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
       q=(x-v)*(fx-fw);    if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
       p=(x-v)*q-(x-w)*r;    m[nrl][ncl] += NR_END;
       q=2.0*(q-r);    m[nrl][ncl] -= nll;
       if (q > 0.0) p = -p;    for (j=ncl+1; j<=nch; j++) 
       q=fabs(q);      m[nrl][j]=m[nrl][j-1]+nlay;
       etemp=e;    
       e=d;    for (i=nrl+1; i<=nrh; i++) {
       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x))      m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
         d=CGOLD*(e=(x >= xm ? a-x : b-x));      for (j=ncl+1; j<=nch; j++) 
       else {        m[i][j]=m[i][j-1]+nlay;
         d=p/q;    }
         u=x+d;    return m; 
         if (u-a < tol2 || b-u < tol2)    /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
           d=SIGN(tol1,xm-x);             &(m[i][j][k]) <=> *((*(m+i) + j)+k)
       }    */
     } else {  }
       d=CGOLD*(e=(x >= xm ? a-x : b-x));  
     }  /*************************free ma3x ************************/
     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d));  void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
     fu=(*f)(u);  {
     if (fu <= fx) {    free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
       if (u >= x) a=x; else b=x;    free((FREE_ARG)(m[nrl]+ncl-NR_END));
       SHFT(v,w,x,u)    free((FREE_ARG)(m+nrl-NR_END));
         SHFT(fv,fw,fx,fu)  }
         } else {  
           if (u < x) a=u; else b=u;  /***************** f1dim *************************/
           if (fu <= fw || w == x) {  extern int ncom; 
             v=w;  extern double *pcom,*xicom;
             w=u;  extern double (*nrfunc)(double []); 
             fv=fw;   
             fw=fu;  double f1dim(double x) 
           } else if (fu <= fv || v == x || v == w) {  { 
             v=u;    int j; 
             fv=fu;    double f;
           }    double *xt; 
         }   
   }    xt=vector(1,ncom); 
   nrerror("Too many iterations in brent");    for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
   *xmin=x;    f=(*nrfunc)(xt); 
   return fx;    free_vector(xt,1,ncom); 
 }    return f; 
   } 
 /****************** mnbrak ***********************/  
   /*****************brent *************************/
 void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc,  double brent(double ax, double bx, double cx, double (*f)(double), double tol,  double *xmin) 
             double (*func)(double))  { 
 {    int iter; 
   double ulim,u,r,q, dum;    double a,b,d,etemp;
   double fu;    double fu,fv,fw,fx;
      double ftemp;
   *fa=(*func)(*ax);    double p,q,r,tol1,tol2,u,v,w,x,xm; 
   *fb=(*func)(*bx);    double e=0.0; 
   if (*fb > *fa) {   
     SHFT(dum,*ax,*bx,dum)    a=(ax < cx ? ax : cx); 
       SHFT(dum,*fb,*fa,dum)    b=(ax > cx ? ax : cx); 
       }    x=w=v=bx; 
   *cx=(*bx)+GOLD*(*bx-*ax);    fw=fv=fx=(*f)(x); 
   *fc=(*func)(*cx);    for (iter=1;iter<=ITMAX;iter++) { 
   while (*fb > *fc) {      xm=0.5*(a+b); 
     r=(*bx-*ax)*(*fb-*fc);      tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
     q=(*bx-*cx)*(*fb-*fa);      /*          if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/      printf(".");fflush(stdout);
       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r));      fprintf(ficlog,".");fflush(ficlog);
     ulim=(*bx)+GLIMIT*(*cx-*bx);  #ifdef DEBUG
     if ((*bx-u)*(u-*cx) > 0.0) {      printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
       fu=(*func)(u);      fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
     } else if ((*cx-u)*(u-ulim) > 0.0) {      /*          if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
       fu=(*func)(u);  #endif
       if (fu < *fc) {      if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
         SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx))        *xmin=x; 
           SHFT(*fb,*fc,fu,(*func)(u))        return fx; 
           }      } 
     } else if ((u-ulim)*(ulim-*cx) >= 0.0) {      ftemp=fu;
       u=ulim;      if (fabs(e) > tol1) { 
       fu=(*func)(u);        r=(x-w)*(fx-fv); 
     } else {        q=(x-v)*(fx-fw); 
       u=(*cx)+GOLD*(*cx-*bx);        p=(x-v)*q-(x-w)*r; 
       fu=(*func)(u);        q=2.0*(q-r); 
     }        if (q > 0.0) p = -p; 
     SHFT(*ax,*bx,*cx,u)        q=fabs(q); 
       SHFT(*fa,*fb,*fc,fu)        etemp=e; 
       }        e=d; 
 }        if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
           d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
 /*************** linmin ************************/        else { 
           d=p/q; 
 int ncom;          u=x+d; 
 double *pcom,*xicom;          if (u-a < tol2 || b-u < tol2) 
 double (*nrfunc)(double []);            d=SIGN(tol1,xm-x); 
          } 
 void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []))      } else { 
 {        d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
   double brent(double ax, double bx, double cx,      } 
                double (*f)(double), double tol, double *xmin);      u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
   double f1dim(double x);      fu=(*f)(u); 
   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb,      if (fu <= fx) { 
               double *fc, double (*func)(double));        if (u >= x) a=x; else b=x; 
   int j;        SHFT(v,w,x,u) 
   double xx,xmin,bx,ax;          SHFT(fv,fw,fx,fu) 
   double fx,fb,fa;          } else { 
              if (u < x) a=u; else b=u; 
   ncom=n;            if (fu <= fw || w == x) { 
   pcom=vector(1,n);              v=w; 
   xicom=vector(1,n);              w=u; 
   nrfunc=func;              fv=fw; 
   for (j=1;j<=n;j++) {              fw=fu; 
     pcom[j]=p[j];            } else if (fu <= fv || v == x || v == w) { 
     xicom[j]=xi[j];              v=u; 
   }              fv=fu; 
   ax=0.0;            } 
   xx=1.0;          } 
   mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);    } 
   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin);    nrerror("Too many iterations in brent"); 
 #ifdef DEBUG    *xmin=x; 
   printf("retour brent fret=%.12e xmin=%.12e\n",*fret,xmin);    return fx; 
 #endif  } 
   for (j=1;j<=n;j++) {  
     xi[j] *= xmin;  /****************** mnbrak ***********************/
     p[j] += xi[j];  
   }  void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
   free_vector(xicom,1,n);              double (*func)(double)) 
   free_vector(pcom,1,n);  { 
 }    double ulim,u,r,q, dum;
     double fu; 
 /*************** powell ************************/   
 void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret,    *fa=(*func)(*ax); 
             double (*func)(double []))    *fb=(*func)(*bx); 
 {    if (*fb > *fa) { 
   void linmin(double p[], double xi[], int n, double *fret,      SHFT(dum,*ax,*bx,dum) 
               double (*func)(double []));        SHFT(dum,*fb,*fa,dum) 
   int i,ibig,j;        } 
   double del,t,*pt,*ptt,*xit;    *cx=(*bx)+GOLD*(*bx-*ax); 
   double fp,fptt;    *fc=(*func)(*cx); 
   double *xits;    while (*fb > *fc) { 
   pt=vector(1,n);      r=(*bx-*ax)*(*fb-*fc); 
   ptt=vector(1,n);      q=(*bx-*cx)*(*fb-*fa); 
   xit=vector(1,n);      u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
   xits=vector(1,n);        (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); 
   *fret=(*func)(p);      ulim=(*bx)+GLIMIT*(*cx-*bx); 
   for (j=1;j<=n;j++) pt[j]=p[j];      if ((*bx-u)*(u-*cx) > 0.0) { 
   for (*iter=1;;++(*iter)) {        fu=(*func)(u); 
     fp=(*fret);      } else if ((*cx-u)*(u-ulim) > 0.0) { 
     ibig=0;        fu=(*func)(u); 
     del=0.0;        if (fu < *fc) { 
     printf("\nPowell iter=%d -2*LL=%.12f",*iter,*fret);          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
     for (i=1;i<=n;i++)            SHFT(*fb,*fc,fu,(*func)(u)) 
       printf(" %d %.12f",i, p[i]);            } 
     printf("\n");      } else if ((u-ulim)*(ulim-*cx) >= 0.0) { 
     for (i=1;i<=n;i++) {        u=ulim; 
       for (j=1;j<=n;j++) xit[j]=xi[j][i];        fu=(*func)(u); 
       fptt=(*fret);      } else { 
 #ifdef DEBUG        u=(*cx)+GOLD*(*cx-*bx); 
       printf("fret=%lf \n",*fret);        fu=(*func)(u); 
 #endif      } 
       printf("%d",i);fflush(stdout);      SHFT(*ax,*bx,*cx,u) 
       linmin(p,xit,n,fret,func);        SHFT(*fa,*fb,*fc,fu) 
       if (fabs(fptt-(*fret)) > del) {        } 
         del=fabs(fptt-(*fret));  } 
         ibig=i;  
       }  /*************** linmin ************************/
 #ifdef DEBUG  
       printf("%d %.12e",i,(*fret));  int ncom; 
       for (j=1;j<=n;j++) {  double *pcom,*xicom;
         xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);  double (*nrfunc)(double []); 
         printf(" x(%d)=%.12e",j,xit[j]);   
       }  void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
       for(j=1;j<=n;j++)  { 
         printf(" p=%.12e",p[j]);    double brent(double ax, double bx, double cx, 
       printf("\n");                 double (*f)(double), double tol, double *xmin); 
 #endif    double f1dim(double x); 
     }    void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
     if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) {                double *fc, double (*func)(double)); 
 #ifdef DEBUG    int j; 
       int k[2],l;    double xx,xmin,bx,ax; 
       k[0]=1;    double fx,fb,fa;
       k[1]=-1;   
       printf("Max: %.12e",(*func)(p));    ncom=n; 
       for (j=1;j<=n;j++)    pcom=vector(1,n); 
         printf(" %.12e",p[j]);    xicom=vector(1,n); 
       printf("\n");    nrfunc=func; 
       for(l=0;l<=1;l++) {    for (j=1;j<=n;j++) { 
         for (j=1;j<=n;j++) {      pcom[j]=p[j]; 
           ptt[j]=p[j]+(p[j]-pt[j])*k[l];      xicom[j]=xi[j]; 
           printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);    } 
         }    ax=0.0; 
         printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));    xx=1.0; 
       }    mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim); 
 #endif    *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); 
   #ifdef DEBUG
     printf("retour brent fret=%.12e xmin=%.12e\n",*fret,xmin);
       free_vector(xit,1,n);    fprintf(ficlog,"retour brent fret=%.12e xmin=%.12e\n",*fret,xmin);
       free_vector(xits,1,n);  #endif
       free_vector(ptt,1,n);    for (j=1;j<=n;j++) { 
       free_vector(pt,1,n);      xi[j] *= xmin; 
       return;      p[j] += xi[j]; 
     }    } 
     if (*iter == ITMAX) nrerror("powell exceeding maximum iterations.");    free_vector(xicom,1,n); 
     for (j=1;j<=n;j++) {    free_vector(pcom,1,n); 
       ptt[j]=2.0*p[j]-pt[j];  } 
       xit[j]=p[j]-pt[j];  
       pt[j]=p[j];  /*************** powell ************************/
     }  void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
     fptt=(*func)(ptt);              double (*func)(double [])) 
     if (fptt < fp) {  { 
       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt);    void linmin(double p[], double xi[], int n, double *fret, 
       if (t < 0.0) {                double (*func)(double [])); 
         linmin(p,xit,n,fret,func);    int i,ibig,j; 
         for (j=1;j<=n;j++) {    double del,t,*pt,*ptt,*xit;
           xi[j][ibig]=xi[j][n];    double fp,fptt;
           xi[j][n]=xit[j];    double *xits;
         }    pt=vector(1,n); 
 #ifdef DEBUG    ptt=vector(1,n); 
         printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);    xit=vector(1,n); 
         for(j=1;j<=n;j++)    xits=vector(1,n); 
           printf(" %.12e",xit[j]);    *fret=(*func)(p); 
         printf("\n");    for (j=1;j<=n;j++) pt[j]=p[j]; 
 #endif    for (*iter=1;;++(*iter)) { 
       }      fp=(*fret); 
     }      ibig=0; 
   }      del=0.0; 
 }      printf("\nPowell iter=%d -2*LL=%.12f",*iter,*fret);
       fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f",*iter,*fret);
 /**** Prevalence limit ****************/      fprintf(ficrespow,"%d %.12f",*iter,*fret);
       for (i=1;i<=n;i++) {
 double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int ij)        printf(" %d %.12f",i, p[i]);
 {        fprintf(ficlog," %d %.12lf",i, p[i]);
   /* Computes the prevalence limit in each live state at age x by left multiplying the unit        fprintf(ficrespow," %.12lf", p[i]);
      matrix by transitions matrix until convergence is reached */      }
       printf("\n");
   int i, ii,j,k;      fprintf(ficlog,"\n");
   double min, max, maxmin, maxmax,sumnew=0.;      fprintf(ficrespow,"\n");
   double **matprod2();      for (i=1;i<=n;i++) { 
   double **out, cov[NCOVMAX], **pmij();        for (j=1;j<=n;j++) xit[j]=xi[j][i]; 
   double **newm;        fptt=(*fret); 
   double agefin, delaymax=50 ; /* Max number of years to converge */  #ifdef DEBUG
         printf("fret=%lf \n",*fret);
   for (ii=1;ii<=nlstate+ndeath;ii++)        fprintf(ficlog,"fret=%lf \n",*fret);
     for (j=1;j<=nlstate+ndeath;j++){  #endif
       oldm[ii][j]=(ii==j ? 1.0 : 0.0);        printf("%d",i);fflush(stdout);
     }        fprintf(ficlog,"%d",i);fflush(ficlog);
         linmin(p,xit,n,fret,func); 
    cov[1]=1.;        if (fabs(fptt-(*fret)) > del) { 
            del=fabs(fptt-(*fret)); 
  /* Even if hstepm = 1, at least one multiplication by the unit matrix */          ibig=i; 
   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){        } 
     newm=savm;  #ifdef DEBUG
     /* Covariates have to be included here again */        printf("%d %.12e",i,(*fret));
      cov[2]=agefin;        fprintf(ficlog,"%d %.12e",i,(*fret));
          for (j=1;j<=n;j++) {
       for (k=1; k<=cptcovn;k++) {          xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
         cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]];          printf(" x(%d)=%.12e",j,xit[j]);
         /*      printf("ij=%d k=%d Tvar[k]=%d nbcode=%d cov=%lf codtab[ij][Tvar[k]]=%d \n",ij,k, Tvar[k],nbcode[Tvar[k]][codtab[ij][Tvar[k]]],cov[2+k], codtab[ij][Tvar[k]]);*/          fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
       }        }
       for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];        for(j=1;j<=n;j++) {
       for (k=1; k<=cptcovprod;k++)          printf(" p=%.12e",p[j]);
         cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];          fprintf(ficlog," p=%.12e",p[j]);
         }
       /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/        printf("\n");
       /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/        fprintf(ficlog,"\n");
       /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/  #endif
     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);      } 
       if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) {
     savm=oldm;  #ifdef DEBUG
     oldm=newm;        int k[2],l;
     maxmax=0.;        k[0]=1;
     for(j=1;j<=nlstate;j++){        k[1]=-1;
       min=1.;        printf("Max: %.12e",(*func)(p));
       max=0.;        fprintf(ficlog,"Max: %.12e",(*func)(p));
       for(i=1; i<=nlstate; i++) {        for (j=1;j<=n;j++) {
         sumnew=0;          printf(" %.12e",p[j]);
         for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];          fprintf(ficlog," %.12e",p[j]);
         prlim[i][j]= newm[i][j]/(1-sumnew);        }
         max=FMAX(max,prlim[i][j]);        printf("\n");
         min=FMIN(min,prlim[i][j]);        fprintf(ficlog,"\n");
       }        for(l=0;l<=1;l++) {
       maxmin=max-min;          for (j=1;j<=n;j++) {
       maxmax=FMAX(maxmax,maxmin);            ptt[j]=p[j]+(p[j]-pt[j])*k[l];
     }            printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
     if(maxmax < ftolpl){            fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
       return prlim;          }
     }          printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
   }          fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
 }        }
   #endif
 /*************** transition probabilities ***************/  
   
 double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )        free_vector(xit,1,n); 
 {        free_vector(xits,1,n); 
   double s1, s2;        free_vector(ptt,1,n); 
   /*double t34;*/        free_vector(pt,1,n); 
   int i,j,j1, nc, ii, jj;        return; 
       } 
     for(i=1; i<= nlstate; i++){      if (*iter == ITMAX) nrerror("powell exceeding maximum iterations."); 
     for(j=1; j<i;j++){      for (j=1;j<=n;j++) { 
       for (nc=1, s2=0.;nc <=ncovmodel; nc++){        ptt[j]=2.0*p[j]-pt[j]; 
         /*s2 += param[i][j][nc]*cov[nc];*/        xit[j]=p[j]-pt[j]; 
         s2 += x[(i-1)*nlstate*ncovmodel+(j-1)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];        pt[j]=p[j]; 
         /*printf("Int j<i s1=%.17e, s2=%.17e\n",s1,s2);*/      } 
       }      fptt=(*func)(ptt); 
       ps[i][j]=s2;      if (fptt < fp) { 
       /*printf("s1=%.17e, s2=%.17e\n",s1,s2);*/        t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); 
     }        if (t < 0.0) { 
     for(j=i+1; j<=nlstate+ndeath;j++){          linmin(p,xit,n,fret,func); 
       for (nc=1, s2=0.;nc <=ncovmodel; nc++){          for (j=1;j<=n;j++) { 
         s2 += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];            xi[j][ibig]=xi[j][n]; 
         /*printf("Int j>i s1=%.17e, s2=%.17e %lx %lx\n",s1,s2,s1,s2);*/            xi[j][n]=xit[j]; 
       }          }
       ps[i][j]=s2;  #ifdef DEBUG
     }          printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
   }          fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
     /*ps[3][2]=1;*/          for(j=1;j<=n;j++){
             printf(" %.12e",xit[j]);
   for(i=1; i<= nlstate; i++){            fprintf(ficlog," %.12e",xit[j]);
      s1=0;          }
     for(j=1; j<i; j++)          printf("\n");
       s1+=exp(ps[i][j]);          fprintf(ficlog,"\n");
     for(j=i+1; j<=nlstate+ndeath; j++)  #endif
       s1+=exp(ps[i][j]);        }
     ps[i][i]=1./(s1+1.);      } 
     for(j=1; j<i; j++)    } 
       ps[i][j]= exp(ps[i][j])*ps[i][i];  } 
     for(j=i+1; j<=nlstate+ndeath; j++)  
       ps[i][j]= exp(ps[i][j])*ps[i][i];  /**** Prevalence limit (stable prevalence)  ****************/
     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */  
   } /* end i */  double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int ij)
   {
   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){    /* Computes the prevalence limit in each live state at age x by left multiplying the unit
     for(jj=1; jj<= nlstate+ndeath; jj++){       matrix by transitions matrix until convergence is reached */
       ps[ii][jj]=0;  
       ps[ii][ii]=1;    int i, ii,j,k;
     }    double min, max, maxmin, maxmax,sumnew=0.;
   }    double **matprod2();
     double **out, cov[NCOVMAX], **pmij();
     double **newm;
   /*   for(ii=1; ii<= nlstate+ndeath; ii++){    double agefin, delaymax=50 ; /* Max number of years to converge */
     for(jj=1; jj<= nlstate+ndeath; jj++){  
      printf("%lf ",ps[ii][jj]);    for (ii=1;ii<=nlstate+ndeath;ii++)
    }      for (j=1;j<=nlstate+ndeath;j++){
     printf("\n ");        oldm[ii][j]=(ii==j ? 1.0 : 0.0);
     }      }
     printf("\n ");printf("%lf ",cov[2]);*/  
 /*     cov[1]=1.;
   for(i=1; i<= npar; i++) printf("%f ",x[i]);   
   goto end;*/   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
     return ps;    for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
 }      newm=savm;
       /* Covariates have to be included here again */
 /**************** Product of 2 matrices ******************/       cov[2]=agefin;
     
 double **matprod2(double **out, double **in,long nrl, long nrh, long ncl, long nch, long ncolol, long ncoloh, double **b)        for (k=1; k<=cptcovn;k++) {
 {          cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]];
   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times          /*      printf("ij=%d k=%d Tvar[k]=%d nbcode=%d cov=%lf codtab[ij][Tvar[k]]=%d \n",ij,k, Tvar[k],nbcode[Tvar[k]][codtab[ij][Tvar[k]]],cov[2+k], codtab[ij][Tvar[k]]);*/
      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */        }
   /* in, b, out are matrice of pointers which should have been initialized        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];
      before: only the contents of out is modified. The function returns        for (k=1; k<=cptcovprod;k++)
      a pointer to pointers identical to out */          cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];
   long i, j, k;  
   for(i=nrl; i<= nrh; i++)        /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
     for(k=ncolol; k<=ncoloh; k++)        /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
       for(j=ncl,out[i][k]=0.; j<=nch; j++)        /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
         out[i][k] +=in[i][j]*b[j][k];      out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
   
   return out;      savm=oldm;
 }      oldm=newm;
       maxmax=0.;
       for(j=1;j<=nlstate;j++){
 /************* Higher Matrix Product ***************/        min=1.;
         max=0.;
 double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij )        for(i=1; i<=nlstate; i++) {
 {          sumnew=0;
   /* Computes the transition matrix starting at age 'age' over 'nhstepm*hstepm*stepm' month          for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
      duration (i.e. until          prlim[i][j]= newm[i][j]/(1-sumnew);
      age (in years)  age+nhstepm*stepm/12) by multiplying nhstepm*hstepm matrices.          max=FMAX(max,prlim[i][j]);
      Output is stored in matrix po[i][j][h] for h every 'hstepm' step          min=FMIN(min,prlim[i][j]);
      (typically every 2 years instead of every month which is too big).        }
      Model is determined by parameters x and covariates have to be        maxmin=max-min;
      included manually here.        maxmax=FMAX(maxmax,maxmin);
       }
      */      if(maxmax < ftolpl){
         return prlim;
   int i, j, d, h, k;      }
   double **out, cov[NCOVMAX];    }
   double **newm;  }
   
   /* Hstepm could be zero and should return the unit matrix */  /*************** transition probabilities ***************/ 
   for (i=1;i<=nlstate+ndeath;i++)  
     for (j=1;j<=nlstate+ndeath;j++){  double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
       oldm[i][j]=(i==j ? 1.0 : 0.0);  {
       po[i][j][0]=(i==j ? 1.0 : 0.0);    double s1, s2;
     }    /*double t34;*/
   /* Even if hstepm = 1, at least one multiplication by the unit matrix */    int i,j,j1, nc, ii, jj;
   for(h=1; h <=nhstepm; h++){  
     for(d=1; d <=hstepm; d++){      for(i=1; i<= nlstate; i++){
       newm=savm;      for(j=1; j<i;j++){
       /* Covariates have to be included here again */        for (nc=1, s2=0.;nc <=ncovmodel; nc++){
       cov[1]=1.;          /*s2 += param[i][j][nc]*cov[nc];*/
       cov[2]=age+((h-1)*hstepm + (d-1))*stepm/YEARM;          s2 += x[(i-1)*nlstate*ncovmodel+(j-1)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];
       for (k=1; k<=cptcovn;k++) cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]];          /*printf("Int j<i s1=%.17e, s2=%.17e\n",s1,s2);*/
       for (k=1; k<=cptcovage;k++)        }
         cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];        ps[i][j]=s2;
       for (k=1; k<=cptcovprod;k++)        /*printf("s1=%.17e, s2=%.17e\n",s1,s2);*/
         cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];      }
       for(j=i+1; j<=nlstate+ndeath;j++){
         for (nc=1, s2=0.;nc <=ncovmodel; nc++){
       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/          s2 += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];
       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/          /*printf("Int j>i s1=%.17e, s2=%.17e %lx %lx\n",s1,s2,s1,s2);*/
       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,        }
                    pmij(pmmij,cov,ncovmodel,x,nlstate));        ps[i][j]=s2;
       savm=oldm;      }
       oldm=newm;    }
     }      /*ps[3][2]=1;*/
     for(i=1; i<=nlstate+ndeath; i++)  
       for(j=1;j<=nlstate+ndeath;j++) {    for(i=1; i<= nlstate; i++){
         po[i][j][h]=newm[i][j];       s1=0;
         /*printf("i=%d j=%d h=%d po[i][j][h]=%f ",i,j,h,po[i][j][h]);      for(j=1; j<i; j++)
          */        s1+=exp(ps[i][j]);
       }      for(j=i+1; j<=nlstate+ndeath; j++)
   } /* end h */        s1+=exp(ps[i][j]);
   return po;      ps[i][i]=1./(s1+1.);
 }      for(j=1; j<i; j++)
         ps[i][j]= exp(ps[i][j])*ps[i][i];
       for(j=i+1; j<=nlstate+ndeath; j++)
 /*************** log-likelihood *************/        ps[i][j]= exp(ps[i][j])*ps[i][i];
 double func( double *x)      /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
 {    } /* end i */
   int i, ii, j, k, mi, d, kk;  
   double l, ll[NLSTATEMAX], cov[NCOVMAX];    for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
   double **out;      for(jj=1; jj<= nlstate+ndeath; jj++){
   double sw; /* Sum of weights */        ps[ii][jj]=0;
   double lli; /* Individual log likelihood */        ps[ii][ii]=1;
   long ipmx;      }
   /*extern weight */    }
   /* We are differentiating ll according to initial status */  
   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/  
   /*for(i=1;i<imx;i++)    /*   for(ii=1; ii<= nlstate+ndeath; ii++){
     printf(" %d\n",s[4][i]);      for(jj=1; jj<= nlstate+ndeath; jj++){
   */       printf("%lf ",ps[ii][jj]);
   cov[1]=1.;     }
       printf("\n ");
   for(k=1; k<=nlstate; k++) ll[k]=0.;      }
   for (i=1,ipmx=0, sw=0.; i<=imx; i++){      printf("\n ");printf("%lf ",cov[2]);*/
     for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];  /*
     for(mi=1; mi<= wav[i]-1; mi++){    for(i=1; i<= npar; i++) printf("%f ",x[i]);
       for (ii=1;ii<=nlstate+ndeath;ii++)    goto end;*/
         for (j=1;j<=nlstate+ndeath;j++) oldm[ii][j]=(ii==j ? 1.0 : 0.0);      return ps;
       for(d=0; d<dh[mi][i]; d++){  }
         newm=savm;  
         cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;  /**************** Product of 2 matrices ******************/
         for (kk=1; kk<=cptcovage;kk++) {  
           cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];  double **matprod2(double **out, double **in,long nrl, long nrh, long ncl, long nch, long ncolol, long ncoloh, double **b)
         }  {
            /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
         out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,       b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                      1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));    /* in, b, out are matrice of pointers which should have been initialized 
         savm=oldm;       before: only the contents of out is modified. The function returns
         oldm=newm;       a pointer to pointers identical to out */
            long i, j, k;
            for(i=nrl; i<= nrh; i++)
       } /* end mult */      for(k=ncolol; k<=ncoloh; k++)
              for(j=ncl,out[i][k]=0.; j<=nch; j++)
       lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);          out[i][k] +=in[i][j]*b[j][k];
       /* printf(" %f ",out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/  
       ipmx +=1;    return out;
       sw += weight[i];  }
       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;  
     } /* end of wave */  
   } /* end of individual */  /************* Higher Matrix Product ***************/
   
   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];  double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij )
   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */  {
   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */    /* Computes the transition matrix starting at age 'age' over 
   return -l;       'nhstepm*hstepm*stepm' months (i.e. until
 }       age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
        nhstepm*hstepm matrices. 
        Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
 /*********** Maximum Likelihood Estimation ***************/       (typically every 2 years instead of every month which is too big 
        for the memory).
 void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))       Model is determined by parameters x and covariates have to be 
 {       included manually here. 
   int i,j, iter;  
   double **xi,*delti;       */
   double fret;  
   xi=matrix(1,npar,1,npar);    int i, j, d, h, k;
   for (i=1;i<=npar;i++)    double **out, cov[NCOVMAX];
     for (j=1;j<=npar;j++)    double **newm;
       xi[i][j]=(i==j ? 1.0 : 0.0);  
   printf("Powell\n");    /* Hstepm could be zero and should return the unit matrix */
   powell(p,xi,npar,ftol,&iter,&fret,func);    for (i=1;i<=nlstate+ndeath;i++)
       for (j=1;j<=nlstate+ndeath;j++){
    printf("\n#Number of iterations = %d, -2 Log likelihood = %.12f\n",iter,func(p));        oldm[i][j]=(i==j ? 1.0 : 0.0);
   fprintf(ficres,"#Number of iterations = %d, -2 Log likelihood = %.12f \n",iter,func(p));        po[i][j][0]=(i==j ? 1.0 : 0.0);
       }
 }    /* Even if hstepm = 1, at least one multiplication by the unit matrix */
     for(h=1; h <=nhstepm; h++){
 /**** Computes Hessian and covariance matrix ***/      for(d=1; d <=hstepm; d++){
 void hesscov(double **matcov, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))        newm=savm;
 {        /* Covariates have to be included here again */
   double  **a,**y,*x,pd;        cov[1]=1.;
   double **hess;        cov[2]=age+((h-1)*hstepm + (d-1))*stepm/YEARM;
   int i, j,jk;        for (k=1; k<=cptcovn;k++) cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]];
   int *indx;        for (k=1; k<=cptcovage;k++)
           cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];
   double hessii(double p[], double delta, int theta, double delti[]);        for (k=1; k<=cptcovprod;k++)
   double hessij(double p[], double delti[], int i, int j);          cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];
   void lubksb(double **a, int npar, int *indx, double b[]) ;  
   void ludcmp(double **a, int npar, int *indx, double *d) ;  
         /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
   hess=matrix(1,npar,1,npar);        /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
         out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
   printf("\nCalculation of the hessian matrix. Wait...\n");                     pmij(pmmij,cov,ncovmodel,x,nlstate));
   for (i=1;i<=npar;i++){        savm=oldm;
     printf("%d",i);fflush(stdout);        oldm=newm;
     hess[i][i]=hessii(p,ftolhess,i,delti);      }
     /*printf(" %f ",p[i]);*/      for(i=1; i<=nlstate+ndeath; i++)
     /*printf(" %lf ",hess[i][i]);*/        for(j=1;j<=nlstate+ndeath;j++) {
   }          po[i][j][h]=newm[i][j];
            /*printf("i=%d j=%d h=%d po[i][j][h]=%f ",i,j,h,po[i][j][h]);
   for (i=1;i<=npar;i++) {           */
     for (j=1;j<=npar;j++)  {        }
       if (j>i) {    } /* end h */
         printf(".%d%d",i,j);fflush(stdout);    return po;
         hess[i][j]=hessij(p,delti,i,j);  }
         hess[j][i]=hess[i][j];      
         /*printf(" %lf ",hess[i][j]);*/  
       }  /*************** log-likelihood *************/
     }  double func( double *x)
   }  {
   printf("\n");    int i, ii, j, k, mi, d, kk;
     double l, ll[NLSTATEMAX], cov[NCOVMAX];
   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");    double **out;
      double sw; /* Sum of weights */
   a=matrix(1,npar,1,npar);    double lli; /* Individual log likelihood */
   y=matrix(1,npar,1,npar);    int s1, s2;
   x=vector(1,npar);    double bbh, survp;
   indx=ivector(1,npar);    long ipmx;
   for (i=1;i<=npar;i++)    /*extern weight */
     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];    /* We are differentiating ll according to initial status */
   ludcmp(a,npar,indx,&pd);    /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
     /*for(i=1;i<imx;i++) 
   for (j=1;j<=npar;j++) {      printf(" %d\n",s[4][i]);
     for (i=1;i<=npar;i++) x[i]=0;    */
     x[j]=1;    cov[1]=1.;
     lubksb(a,npar,indx,x);  
     for (i=1;i<=npar;i++){    for(k=1; k<=nlstate; k++) ll[k]=0.;
       matcov[i][j]=x[i];  
     }    if(mle==1){
   }      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
         for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
   printf("\n#Hessian matrix#\n");        for(mi=1; mi<= wav[i]-1; mi++){
   for (i=1;i<=npar;i++) {          for (ii=1;ii<=nlstate+ndeath;ii++)
     for (j=1;j<=npar;j++) {            for (j=1;j<=nlstate+ndeath;j++){
       printf("%.3e ",hess[i][j]);              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
     }              savm[ii][j]=(ii==j ? 1.0 : 0.0);
     printf("\n");            }
   }          for(d=0; d<dh[mi][i]; d++){
             newm=savm;
   /* Recompute Inverse */            cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
   for (i=1;i<=npar;i++)            for (kk=1; kk<=cptcovage;kk++) {
     for (j=1;j<=npar;j++) a[i][j]=matcov[i][j];              cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
   ludcmp(a,npar,indx,&pd);            }
             out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
   /*  printf("\n#Hessian matrix recomputed#\n");                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
             savm=oldm;
   for (j=1;j<=npar;j++) {            oldm=newm;
     for (i=1;i<=npar;i++) x[i]=0;          } /* end mult */
     x[j]=1;        
     lubksb(a,npar,indx,x);          /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
     for (i=1;i<=npar;i++){          /* But now since version 0.9 we anticipate for bias and large stepm.
       y[i][j]=x[i];           * If stepm is larger than one month (smallest stepm) and if the exact delay 
       printf("%.3e ",y[i][j]);           * (in months) between two waves is not a multiple of stepm, we rounded to 
     }           * the nearest (and in case of equal distance, to the lowest) interval but now
     printf("\n");           * we keep into memory the bias bh[mi][i] and also the previous matrix product
   }           * (i.e to dh[mi][i]-1) saved in 'savm'. The we inter(extra)polate the
   */           * probability in order to take into account the bias as a fraction of the way
            * from savm to out if bh is neagtive or even beyond if bh is positive. bh varies
   free_matrix(a,1,npar,1,npar);           * -stepm/2 to stepm/2 .
   free_matrix(y,1,npar,1,npar);           * For stepm=1 the results are the same as for previous versions of Imach.
   free_vector(x,1,npar);           * For stepm > 1 the results are less biased than in previous versions. 
   free_ivector(indx,1,npar);           */
   free_matrix(hess,1,npar,1,npar);          s1=s[mw[mi][i]][i];
           s2=s[mw[mi+1][i]][i];
           bbh=(double)bh[mi][i]/(double)stepm; 
 }          /* bias is positive if real duration
            * is higher than the multiple of stepm and negative otherwise.
 /*************** hessian matrix ****************/           */
 double hessii( double x[], double delta, int theta, double delti[])          /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
 {          if( s2 > nlstate){ 
   int i;            /* i.e. if s2 is a death state and if the date of death is known then the contribution
   int l=1, lmax=20;               to the likelihood is the probability to die between last step unit time and current 
   double k1,k2;               step unit time, which is also the differences between probability to die before dh 
   double p2[NPARMAX+1];               and probability to die before dh-stepm . 
   double res;               In version up to 0.92 likelihood was computed
   double delt, delts, nkhi=10.,nkhif=1., khi=1.e-4;          as if date of death was unknown. Death was treated as any other
   double fx;          health state: the date of the interview describes the actual state
   int k=0,kmax=10;          and not the date of a change in health state. The former idea was
   double l1;          to consider that at each interview the state was recorded
           (healthy, disable or death) and IMaCh was corrected; but when we
   fx=func(x);          introduced the exact date of death then we should have modified
   for (i=1;i<=npar;i++) p2[i]=x[i];          the contribution of an exact death to the likelihood. This new
   for(l=0 ; l <=lmax; l++){          contribution is smaller and very dependent of the step unit
     l1=pow(10,l);          stepm. It is no more the probability to die between last interview
     delts=delt;          and month of death but the probability to survive from last
     for(k=1 ; k <kmax; k=k+1){          interview up to one month before death multiplied by the
       delt = delta*(l1*k);          probability to die within a month. Thanks to Chris
       p2[theta]=x[theta] +delt;          Jackson for correcting this bug.  Former versions increased
       k1=func(p2)-fx;          mortality artificially. The bad side is that we add another loop
       p2[theta]=x[theta]-delt;          which slows down the processing. The difference can be up to 10%
       k2=func(p2)-fx;          lower mortality.
       /*res= (k1-2.0*fx+k2)/delt/delt; */            */
       res= (k1+k2)/delt/delt/2.; /* Divided by because L and not 2*L */            lli=log(out[s1][s2] - savm[s1][s2]);
                }else{
 #ifdef DEBUG            lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);            /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
 #endif          } 
       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */          /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){          /*if(lli ==000.0)*/
         k=kmax;          /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
       }          ipmx +=1;
       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */          sw += weight[i];
         k=kmax; l=lmax*10.;          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
       }        } /* end of wave */
       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){      } /* end of individual */
         delts=delt;    }  else if(mle==2){
       }      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
     }        for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
   }        for(mi=1; mi<= wav[i]-1; mi++){
   delti[theta]=delts;          for (ii=1;ii<=nlstate+ndeath;ii++)
   return res;            for (j=1;j<=nlstate+ndeath;j++){
                oldm[ii][j]=(ii==j ? 1.0 : 0.0);
 }              savm[ii][j]=(ii==j ? 1.0 : 0.0);
             }
 double hessij( double x[], double delti[], int thetai,int thetaj)          for(d=0; d<=dh[mi][i]; d++){
 {            newm=savm;
   int i;            cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
   int l=1, l1, lmax=20;            for (kk=1; kk<=cptcovage;kk++) {
   double k1,k2,k3,k4,res,fx;              cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
   double p2[NPARMAX+1];            }
   int k;            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                          1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
   fx=func(x);            savm=oldm;
   for (k=1; k<=2; k++) {            oldm=newm;
     for (i=1;i<=npar;i++) p2[i]=x[i];          } /* end mult */
     p2[thetai]=x[thetai]+delti[thetai]/k;        
     p2[thetaj]=x[thetaj]+delti[thetaj]/k;          /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
     k1=func(p2)-fx;          /* But now since version 0.9 we anticipate for bias and large stepm.
             * If stepm is larger than one month (smallest stepm) and if the exact delay 
     p2[thetai]=x[thetai]+delti[thetai]/k;           * (in months) between two waves is not a multiple of stepm, we rounded to 
     p2[thetaj]=x[thetaj]-delti[thetaj]/k;           * the nearest (and in case of equal distance, to the lowest) interval but now
     k2=func(p2)-fx;           * we keep into memory the bias bh[mi][i] and also the previous matrix product
             * (i.e to dh[mi][i]-1) saved in 'savm'. The we inter(extra)polate the
     p2[thetai]=x[thetai]-delti[thetai]/k;           * probability in order to take into account the bias as a fraction of the way
     p2[thetaj]=x[thetaj]+delti[thetaj]/k;           * from savm to out if bh is neagtive or even beyond if bh is positive. bh varies
     k3=func(p2)-fx;           * -stepm/2 to stepm/2 .
             * For stepm=1 the results are the same as for previous versions of Imach.
     p2[thetai]=x[thetai]-delti[thetai]/k;           * For stepm > 1 the results are less biased than in previous versions. 
     p2[thetaj]=x[thetaj]-delti[thetaj]/k;           */
     k4=func(p2)-fx;          s1=s[mw[mi][i]][i];
     res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /* Because of L not 2*L */          s2=s[mw[mi+1][i]][i];
 #ifdef DEBUG          bbh=(double)bh[mi][i]/(double)stepm; 
     printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);          /* bias is positive if real duration
 #endif           * is higher than the multiple of stepm and negative otherwise.
   }           */
   return res;          lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
 }          /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
           /*lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.-+bh)*out[s1][s2])); */ /* exponential interpolation */
 /************** Inverse of matrix **************/          /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
 void ludcmp(double **a, int n, int *indx, double *d)          /*if(lli ==000.0)*/
 {          /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
   int i,imax,j,k;          ipmx +=1;
   double big,dum,sum,temp;          sw += weight[i];
   double *vv;          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
          } /* end of wave */
   vv=vector(1,n);      } /* end of individual */
   *d=1.0;    }  else if(mle==3){  /* exponential inter-extrapolation */
   for (i=1;i<=n;i++) {      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
     big=0.0;        for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
     for (j=1;j<=n;j++)        for(mi=1; mi<= wav[i]-1; mi++){
       if ((temp=fabs(a[i][j])) > big) big=temp;          for (ii=1;ii<=nlstate+ndeath;ii++)
     if (big == 0.0) nrerror("Singular matrix in routine ludcmp");            for (j=1;j<=nlstate+ndeath;j++){
     vv[i]=1.0/big;              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
   }              savm[ii][j]=(ii==j ? 1.0 : 0.0);
   for (j=1;j<=n;j++) {            }
     for (i=1;i<j;i++) {          for(d=0; d<dh[mi][i]; d++){
       sum=a[i][j];            newm=savm;
       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j];            cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
       a[i][j]=sum;            for (kk=1; kk<=cptcovage;kk++) {
     }              cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
     big=0.0;            }
     for (i=j;i<=n;i++) {            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
       sum=a[i][j];                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
       for (k=1;k<j;k++)            savm=oldm;
         sum -= a[i][k]*a[k][j];            oldm=newm;
       a[i][j]=sum;          } /* end mult */
       if ( (dum=vv[i]*fabs(sum)) >= big) {        
         big=dum;          /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
         imax=i;          /* But now since version 0.9 we anticipate for bias and large stepm.
       }           * If stepm is larger than one month (smallest stepm) and if the exact delay 
     }           * (in months) between two waves is not a multiple of stepm, we rounded to 
     if (j != imax) {           * the nearest (and in case of equal distance, to the lowest) interval but now
       for (k=1;k<=n;k++) {           * we keep into memory the bias bh[mi][i] and also the previous matrix product
         dum=a[imax][k];           * (i.e to dh[mi][i]-1) saved in 'savm'. The we inter(extra)polate the
         a[imax][k]=a[j][k];           * probability in order to take into account the bias as a fraction of the way
         a[j][k]=dum;           * from savm to out if bh is neagtive or even beyond if bh is positive. bh varies
       }           * -stepm/2 to stepm/2 .
       *d = -(*d);           * For stepm=1 the results are the same as for previous versions of Imach.
       vv[imax]=vv[j];           * For stepm > 1 the results are less biased than in previous versions. 
     }           */
     indx[j]=imax;          s1=s[mw[mi][i]][i];
     if (a[j][j] == 0.0) a[j][j]=TINY;          s2=s[mw[mi+1][i]][i];
     if (j != n) {          bbh=(double)bh[mi][i]/(double)stepm; 
       dum=1.0/(a[j][j]);          /* bias is positive if real duration
       for (i=j+1;i<=n;i++) a[i][j] *= dum;           * is higher than the multiple of stepm and negative otherwise.
     }           */
   }          /* lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); */ /* linear interpolation */
   free_vector(vv,1,n);  /* Doesn't work */          lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
 ;          /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
 }          /*if(lli ==000.0)*/
           /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
 void lubksb(double **a, int n, int *indx, double b[])          ipmx +=1;
 {          sw += weight[i];
   int i,ii=0,ip,j;          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
   double sum;        } /* end of wave */
        } /* end of individual */
   for (i=1;i<=n;i++) {    }else{  /* ml=4 no inter-extrapolation */
     ip=indx[i];      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
     sum=b[ip];        for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];
     b[ip]=b[i];        for(mi=1; mi<= wav[i]-1; mi++){
     if (ii)          for (ii=1;ii<=nlstate+ndeath;ii++)
       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j];            for (j=1;j<=nlstate+ndeath;j++){
     else if (sum) ii=i;              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
     b[i]=sum;              savm[ii][j]=(ii==j ? 1.0 : 0.0);
   }            }
   for (i=n;i>=1;i--) {          for(d=0; d<dh[mi][i]; d++){
     sum=b[i];            newm=savm;
     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j];            cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;
     b[i]=sum/a[i][i];            for (kk=1; kk<=cptcovage;kk++) {
   }              cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
 }            }
           
 /************ Frequencies ********************/            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
 void  freqsummary(char fileres[], int agemin, int agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2,double jprev1, double mprev1,double anprev1,double jprev2, double mprev2,double anprev2)                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
 {  /* Some frequencies */            savm=oldm;
              oldm=newm;
   int i, m, jk, k1,i1, j1, bool, z1,z2,j;          } /* end mult */
   double ***freq; /* Frequencies */        
   double *pp;          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
   double pos, k2, dateintsum=0,k2cpt=0;          ipmx +=1;
   FILE *ficresp;          sw += weight[i];
   char fileresp[FILENAMELENGTH];          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
          } /* end of wave */
   pp=vector(1,nlstate);      } /* end of individual */
   probs= ma3x(1,AGESUP,1,NCOVMAX, 1,NCOVMAX);    } /* End of if */
   strcpy(fileresp,"p");    for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
   strcat(fileresp,fileres);    /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
   if((ficresp=fopen(fileresp,"w"))==NULL) {    l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
     printf("Problem with prevalence resultfile: %s\n", fileresp);    return -l;
     exit(0);  }
   }  
   freq= ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,agemin,agemax+3);  
   j1=0;  /*********** Maximum Likelihood Estimation ***************/
    
   j=cptcoveff;  void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
   if (cptcovn<1) {j=1;ncodemax[1]=1;}  {
      int i,j, iter;
   for(k1=1; k1<=j;k1++){    double **xi;
     for(i1=1; i1<=ncodemax[k1];i1++){    double fret;
       j1++;    char filerespow[FILENAMELENGTH];
       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);    xi=matrix(1,npar,1,npar);
         scanf("%d", i);*/    for (i=1;i<=npar;i++)
       for (i=-1; i<=nlstate+ndeath; i++)        for (j=1;j<=npar;j++)
         for (jk=-1; jk<=nlstate+ndeath; jk++)          xi[i][j]=(i==j ? 1.0 : 0.0);
           for(m=agemin; m <= agemax+3; m++)    printf("Powell\n");  fprintf(ficlog,"Powell\n");
             freq[i][jk][m]=0;    strcpy(filerespow,"pow"); 
          strcat(filerespow,fileres);
       dateintsum=0;    if((ficrespow=fopen(filerespow,"w"))==NULL) {
       k2cpt=0;      printf("Problem with resultfile: %s\n", filerespow);
       for (i=1; i<=imx; i++) {      fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
         bool=1;    }
         if  (cptcovn>0) {    fprintf(ficrespow,"# Powell\n# iter -2*LL");
           for (z1=1; z1<=cptcoveff; z1++)    for (i=1;i<=nlstate;i++)
             if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtab[j1][z1]])      for(j=1;j<=nlstate+ndeath;j++)
               bool=0;        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
         }    fprintf(ficrespow,"\n");
         if (bool==1) {    powell(p,xi,npar,ftol,&iter,&fret,func);
           for(m=firstpass; m<=lastpass; m++){  
             k2=anint[m][i]+(mint[m][i]/12.);    fclose(ficrespow);
             if ((k2>=dateprev1) && (k2<=dateprev2)) {    printf("\n#Number of iterations = %d, -2 Log likelihood = %.12f\n",iter,func(p));
               if(agev[m][i]==0) agev[m][i]=agemax+1;    fprintf(ficlog,"\n#Number of iterations = %d, -2 Log likelihood = %.12f \n",iter,func(p));
               if(agev[m][i]==1) agev[m][i]=agemax+2;    fprintf(ficres,"#Number of iterations = %d, -2 Log likelihood = %.12f \n",iter,func(p));
               if (m<lastpass) {  
                 freq[s[m][i]][s[m+1][i]][(int)agev[m][i]] += weight[i];  }
                 freq[s[m][i]][s[m+1][i]][(int) agemax+3] += weight[i];  
               }  /**** Computes Hessian and covariance matrix ***/
                void hesscov(double **matcov, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
               if ((agev[m][i]>1) && (agev[m][i]< (agemax+3))) {  {
                 dateintsum=dateintsum+k2;    double  **a,**y,*x,pd;
                 k2cpt++;    double **hess;
               }    int i, j,jk;
             }    int *indx;
           }  
         }    double hessii(double p[], double delta, int theta, double delti[]);
       }    double hessij(double p[], double delti[], int i, int j);
            void lubksb(double **a, int npar, int *indx, double b[]) ;
       fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);    void ludcmp(double **a, int npar, int *indx, double *d) ;
   
       if  (cptcovn>0) {    hess=matrix(1,npar,1,npar);
         fprintf(ficresp, "\n#********** Variable ");  
         for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);    printf("\nCalculation of the hessian matrix. Wait...\n");
         fprintf(ficresp, "**********\n#");    fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
       }    for (i=1;i<=npar;i++){
       for(i=1; i<=nlstate;i++)      printf("%d",i);fflush(stdout);
         fprintf(ficresp, " Age Prev(%d) N(%d) N",i,i);      fprintf(ficlog,"%d",i);fflush(ficlog);
       fprintf(ficresp, "\n");      hess[i][i]=hessii(p,ftolhess,i,delti);
            /*printf(" %f ",p[i]);*/
       for(i=(int)agemin; i <= (int)agemax+3; i++){      /*printf(" %lf ",hess[i][i]);*/
         if(i==(int)agemax+3)    }
           printf("Total");    
         else    for (i=1;i<=npar;i++) {
           printf("Age %d", i);      for (j=1;j<=npar;j++)  {
         for(jk=1; jk <=nlstate ; jk++){        if (j>i) { 
           for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)          printf(".%d%d",i,j);fflush(stdout);
             pp[jk] += freq[jk][m][i];          fprintf(ficlog,".%d%d",i,j);fflush(ficlog);
         }          hess[i][j]=hessij(p,delti,i,j);
         for(jk=1; jk <=nlstate ; jk++){          hess[j][i]=hess[i][j];    
           for(m=-1, pos=0; m <=0 ; m++)          /*printf(" %lf ",hess[i][j]);*/
             pos += freq[jk][m][i];        }
           if(pp[jk]>=1.e-10)      }
             printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);    }
           else    printf("\n");
             printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);    fprintf(ficlog,"\n");
         }  
     printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
         for(jk=1; jk <=nlstate ; jk++){    fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
           for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)    
             pp[jk] += freq[jk][m][i];    a=matrix(1,npar,1,npar);
         }    y=matrix(1,npar,1,npar);
     x=vector(1,npar);
         for(jk=1,pos=0; jk <=nlstate ; jk++)    indx=ivector(1,npar);
           pos += pp[jk];    for (i=1;i<=npar;i++)
         for(jk=1; jk <=nlstate ; jk++){      for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
           if(pos>=1.e-5)    ludcmp(a,npar,indx,&pd);
             printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);  
           else    for (j=1;j<=npar;j++) {
             printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);      for (i=1;i<=npar;i++) x[i]=0;
           if( i <= (int) agemax){      x[j]=1;
             if(pos>=1.e-5){      lubksb(a,npar,indx,x);
               fprintf(ficresp," %d %.5f %.0f %.0f",i,pp[jk]/pos, pp[jk],pos);      for (i=1;i<=npar;i++){ 
               probs[i][jk][j1]= pp[jk]/pos;        matcov[i][j]=x[i];
               /*printf("\ni=%d jk=%d j1=%d %.5f %.0f %.0f %f",i,jk,j1,pp[jk]/pos, pp[jk],pos,probs[i][jk][j1]);*/      }
             }    }
             else  
               fprintf(ficresp," %d NaNq %.0f %.0f",i,pp[jk],pos);    printf("\n#Hessian matrix#\n");
           }    fprintf(ficlog,"\n#Hessian matrix#\n");
         }    for (i=1;i<=npar;i++) { 
              for (j=1;j<=npar;j++) { 
         for(jk=-1; jk <=nlstate+ndeath; jk++)        printf("%.3e ",hess[i][j]);
           for(m=-1; m <=nlstate+ndeath; m++)        fprintf(ficlog,"%.3e ",hess[i][j]);
             if(freq[jk][m][i] !=0 ) printf(" %d%d=%.0f",jk,m,freq[jk][m][i]);      }
         if(i <= (int) agemax)      printf("\n");
           fprintf(ficresp,"\n");      fprintf(ficlog,"\n");
         printf("\n");    }
       }  
     }    /* Recompute Inverse */
   }    for (i=1;i<=npar;i++)
   dateintmean=dateintsum/k2cpt;      for (j=1;j<=npar;j++) a[i][j]=matcov[i][j];
      ludcmp(a,npar,indx,&pd);
   fclose(ficresp);  
   free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath,(int) agemin,(int) agemax+3);    /*  printf("\n#Hessian matrix recomputed#\n");
   free_vector(pp,1,nlstate);  
      for (j=1;j<=npar;j++) {
   /* End of Freq */      for (i=1;i<=npar;i++) x[i]=0;
 }      x[j]=1;
       lubksb(a,npar,indx,x);
 /************ Prevalence ********************/      for (i=1;i<=npar;i++){ 
 void prevalence(int agemin, float agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, double calagedate)        y[i][j]=x[i];
 {  /* Some frequencies */        printf("%.3e ",y[i][j]);
          fprintf(ficlog,"%.3e ",y[i][j]);
   int i, m, jk, k1, i1, j1, bool, z1,z2,j;      }
   double ***freq; /* Frequencies */      printf("\n");
   double *pp;      fprintf(ficlog,"\n");
   double pos, k2;    }
     */
   pp=vector(1,nlstate);  
   probs= ma3x(1,AGESUP,1,NCOVMAX, 1,NCOVMAX);    free_matrix(a,1,npar,1,npar);
      free_matrix(y,1,npar,1,npar);
   freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,agemin,agemax+3);    free_vector(x,1,npar);
   j1=0;    free_ivector(indx,1,npar);
      free_matrix(hess,1,npar,1,npar);
   j=cptcoveff;  
   if (cptcovn<1) {j=1;ncodemax[1]=1;}  
    }
  for(k1=1; k1<=j;k1++){  
     for(i1=1; i1<=ncodemax[k1];i1++){  /*************** hessian matrix ****************/
       j1++;  double hessii( double x[], double delta, int theta, double delti[])
    {
       for (i=-1; i<=nlstate+ndeath; i++)      int i;
         for (jk=-1; jk<=nlstate+ndeath; jk++)      int l=1, lmax=20;
           for(m=agemin; m <= agemax+3; m++)    double k1,k2;
             freq[i][jk][m]=0;    double p2[NPARMAX+1];
          double res;
       for (i=1; i<=imx; i++) {    double delt, delts, nkhi=10.,nkhif=1., khi=1.e-4;
         bool=1;    double fx;
         if  (cptcovn>0) {    int k=0,kmax=10;
           for (z1=1; z1<=cptcoveff; z1++)    double l1;
             if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtab[j1][z1]])  
               bool=0;    fx=func(x);
         }    for (i=1;i<=npar;i++) p2[i]=x[i];
         if (bool==1) {    for(l=0 ; l <=lmax; l++){
           for(m=firstpass; m<=lastpass; m++){      l1=pow(10,l);
             k2=anint[m][i]+(mint[m][i]/12.);      delts=delt;
             if ((k2>=dateprev1) && (k2<=dateprev2)) {      for(k=1 ; k <kmax; k=k+1){
               if(agev[m][i]==0) agev[m][i]=agemax+1;        delt = delta*(l1*k);
               if(agev[m][i]==1) agev[m][i]=agemax+2;        p2[theta]=x[theta] +delt;
               if (m<lastpass)        k1=func(p2)-fx;
                 if (calagedate>0) freq[s[m][i]][s[m+1][i]][(int)(agev[m][i]+1-((int)calagedate %12)/12.)] += weight[i];        p2[theta]=x[theta]-delt;
               else        k2=func(p2)-fx;
                freq[s[m][i]][s[m+1][i]][(int)agev[m][i]] += weight[i];        /*res= (k1-2.0*fx+k2)/delt/delt; */
                freq[s[m][i]][s[m+1][i]][(int)(agemax+3)] += weight[i];        res= (k1+k2)/delt/delt/2.; /* Divided by because L and not 2*L */
             }        
           }  #ifdef DEBUG
         }        printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
       }        fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
         for(i=(int)agemin; i <= (int)agemax+3; i++){  #endif
           for(jk=1; jk <=nlstate ; jk++){        /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
             for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)        if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
               pp[jk] += freq[jk][m][i];          k=kmax;
           }        }
           for(jk=1; jk <=nlstate ; jk++){        else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
             for(m=-1, pos=0; m <=0 ; m++)          k=kmax; l=lmax*10.;
             pos += freq[jk][m][i];        }
         }        else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                  delts=delt;
          for(jk=1; jk <=nlstate ; jk++){        }
            for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)      }
              pp[jk] += freq[jk][m][i];    }
          }    delti[theta]=delts;
              return res; 
          for(jk=1,pos=0; jk <=nlstate ; jk++) pos += pp[jk];    
   }
          for(jk=1; jk <=nlstate ; jk++){            
            if( i <= (int) agemax){  double hessij( double x[], double delti[], int thetai,int thetaj)
              if(pos>=1.e-5){  {
                probs[i][jk][j1]= pp[jk]/pos;    int i;
              }    int l=1, l1, lmax=20;
            }    double k1,k2,k3,k4,res,fx;
          }    double p2[NPARMAX+1];
              int k;
         }  
     }    fx=func(x);
   }    for (k=1; k<=2; k++) {
       for (i=1;i<=npar;i++) p2[i]=x[i];
        p2[thetai]=x[thetai]+delti[thetai]/k;
   free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath,(int) agemin,(int) agemax+3);      p2[thetaj]=x[thetaj]+delti[thetaj]/k;
   free_vector(pp,1,nlstate);      k1=func(p2)-fx;
      
 }  /* End of Freq */      p2[thetai]=x[thetai]+delti[thetai]/k;
       p2[thetaj]=x[thetaj]-delti[thetaj]/k;
 /************* Waves Concatenation ***************/      k2=func(p2)-fx;
     
 void  concatwav(int wav[], int **dh, int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)      p2[thetai]=x[thetai]-delti[thetai]/k;
 {      p2[thetaj]=x[thetaj]+delti[thetaj]/k;
   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.      k3=func(p2)-fx;
      Death is a valid wave (if date is known).    
      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i      p2[thetai]=x[thetai]-delti[thetai]/k;
      dh[m][i] of dh[mw[mi][i][i] is the delay between two effective waves m=mw[mi][i]      p2[thetaj]=x[thetaj]-delti[thetaj]/k;
      and mw[mi+1][i]. dh depends on stepm.      k4=func(p2)-fx;
      */      res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /* Because of L not 2*L */
   #ifdef DEBUG
   int i, mi, m;      printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;      fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
      double sum=0., jmean=0.;*/  #endif
     }
   int j, k=0,jk, ju, jl;    return res;
   double sum=0.;  }
   jmin=1e+5;  
   jmax=-1;  /************** Inverse of matrix **************/
   jmean=0.;  void ludcmp(double **a, int n, int *indx, double *d) 
   for(i=1; i<=imx; i++){  { 
     mi=0;    int i,imax,j,k; 
     m=firstpass;    double big,dum,sum,temp; 
     while(s[m][i] <= nlstate){    double *vv; 
       if(s[m][i]>=1)   
         mw[++mi][i]=m;    vv=vector(1,n); 
       if(m >=lastpass)    *d=1.0; 
         break;    for (i=1;i<=n;i++) { 
       else      big=0.0; 
         m++;      for (j=1;j<=n;j++) 
     }/* end while */        if ((temp=fabs(a[i][j])) > big) big=temp; 
     if (s[m][i] > nlstate){      if (big == 0.0) nrerror("Singular matrix in routine ludcmp"); 
       mi++;     /* Death is another wave */      vv[i]=1.0/big; 
       /* if(mi==0)  never been interviewed correctly before death */    } 
          /* Only death is a correct wave */    for (j=1;j<=n;j++) { 
       mw[mi][i]=m;      for (i=1;i<j;i++) { 
     }        sum=a[i][j]; 
         for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
     wav[i]=mi;        a[i][j]=sum; 
     if(mi==0)      } 
       printf("Warning, no any valid information for:%d line=%d\n",num[i],i);      big=0.0; 
   }      for (i=j;i<=n;i++) { 
         sum=a[i][j]; 
   for(i=1; i<=imx; i++){        for (k=1;k<j;k++) 
     for(mi=1; mi<wav[i];mi++){          sum -= a[i][k]*a[k][j]; 
       if (stepm <=0)        a[i][j]=sum; 
         dh[mi][i]=1;        if ( (dum=vv[i]*fabs(sum)) >= big) { 
       else{          big=dum; 
         if (s[mw[mi+1][i]][i] > nlstate) {          imax=i; 
           if (agedc[i] < 2*AGESUP) {        } 
           j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12);      } 
           if(j==0) j=1;  /* Survives at least one month after exam */      if (j != imax) { 
           k=k+1;        for (k=1;k<=n;k++) { 
           if (j >= jmax) jmax=j;          dum=a[imax][k]; 
           if (j <= jmin) jmin=j;          a[imax][k]=a[j][k]; 
           sum=sum+j;          a[j][k]=dum; 
           /*if (j<0) printf("j=%d num=%d \n",j,i); */        } 
           }        *d = -(*d); 
         }        vv[imax]=vv[j]; 
         else{      } 
           j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));      indx[j]=imax; 
           k=k+1;      if (a[j][j] == 0.0) a[j][j]=TINY; 
           if (j >= jmax) jmax=j;      if (j != n) { 
           else if (j <= jmin)jmin=j;        dum=1.0/(a[j][j]); 
           /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */        for (i=j+1;i<=n;i++) a[i][j] *= dum; 
           sum=sum+j;      } 
         }    } 
         jk= j/stepm;    free_vector(vv,1,n);  /* Doesn't work */
         jl= j -jk*stepm;  ;
         ju= j -(jk+1)*stepm;  } 
         if(jl <= -ju)  
           dh[mi][i]=jk;  void lubksb(double **a, int n, int *indx, double b[]) 
         else  { 
           dh[mi][i]=jk+1;    int i,ii=0,ip,j; 
         if(dh[mi][i]==0)    double sum; 
           dh[mi][i]=1; /* At least one step */   
       }    for (i=1;i<=n;i++) { 
     }      ip=indx[i]; 
   }      sum=b[ip]; 
   jmean=sum/k;      b[ip]=b[i]; 
   printf("Delay (in months) between two waves Min=%d Max=%d Mean=%f\n\n ",jmin, jmax,jmean);      if (ii) 
  }        for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
 /*********** Tricode ****************************/      else if (sum) ii=i; 
 void tricode(int *Tvar, int **nbcode, int imx)      b[i]=sum; 
 {    } 
   int Ndum[20],ij=1, k, j, i;    for (i=n;i>=1;i--) { 
   int cptcode=0;      sum=b[i]; 
   cptcoveff=0;      for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
        b[i]=sum/a[i][i]; 
   for (k=0; k<19; k++) Ndum[k]=0;    } 
   for (k=1; k<=7; k++) ncodemax[k]=0;  } 
   
   for (j=1; j<=(cptcovn+2*cptcovprod); j++) {  /************ Frequencies ********************/
     for (i=1; i<=imx; i++) {  void  freqsummary(char fileres[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, int *Tvaraff, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2,double jprev1, double mprev1,double anprev1,double jprev2, double mprev2,double anprev2)
       ij=(int)(covar[Tvar[j]][i]);  {  /* Some frequencies */
       Ndum[ij]++;    
       /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/    int i, m, jk, k1,i1, j1, bool, z1,z2,j;
       if (ij > cptcode) cptcode=ij;    int first;
     }    double ***freq; /* Frequencies */
     double *pp, **prop;
     for (i=0; i<=cptcode; i++) {    double pos,posprop, k2, dateintsum=0,k2cpt=0;
       if(Ndum[i]!=0) ncodemax[j]++;    FILE *ficresp;
     }    char fileresp[FILENAMELENGTH];
     ij=1;    
     pp=vector(1,nlstate);
     prop=matrix(1,nlstate,iagemin,iagemax+3);
     for (i=1; i<=ncodemax[j]; i++) {    strcpy(fileresp,"p");
       for (k=0; k<=19; k++) {    strcat(fileresp,fileres);
         if (Ndum[k] != 0) {    if((ficresp=fopen(fileresp,"w"))==NULL) {
           nbcode[Tvar[j]][ij]=k;      printf("Problem with prevalence resultfile: %s\n", fileresp);
                fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
           ij++;      exit(0);
         }    }
         if (ij > ncodemax[j]) break;    freq= ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);
       }      j1=0;
     }    
   }      j=cptcoveff;
     if (cptcovn<1) {j=1;ncodemax[1]=1;}
  for (k=0; k<19; k++) Ndum[k]=0;  
     first=1;
  for (i=1; i<=ncovmodel-2; i++) {  
       ij=Tvar[i];    for(k1=1; k1<=j;k1++){
       Ndum[ij]++;      for(i1=1; i1<=ncodemax[k1];i1++){
     }        j1++;
         /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
  ij=1;          scanf("%d", i);*/
  for (i=1; i<=10; i++) {        for (i=-1; i<=nlstate+ndeath; i++)  
    if((Ndum[i]!=0) && (i<=ncovcol)){          for (jk=-1; jk<=nlstate+ndeath; jk++)  
      Tvaraff[ij]=i;            for(m=iagemin; m <= iagemax+3; m++)
      ij++;              freq[i][jk][m]=0;
    }  
  }      for (i=1; i<=nlstate; i++)  
          for(m=iagemin; m <= iagemax+3; m++)
     cptcoveff=ij-1;          prop[i][m]=0;
 }        
         dateintsum=0;
 /*********** Health Expectancies ****************/        k2cpt=0;
         for (i=1; i<=imx; i++) {
 void evsij(char fileres[], double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int ij, int estepm,double delti[],double **matcov )          bool=1;
           if  (cptcovn>0) {
 {            for (z1=1; z1<=cptcoveff; z1++) 
   /* Health expectancies */              if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtab[j1][z1]]) 
   int i, j, nhstepm, hstepm, h, nstepm, k, cptj;                bool=0;
   double age, agelim, hf;          }
   double ***p3mat,***varhe;          if (bool==1){
   double **dnewm,**doldm;            for(m=firstpass; m<=lastpass; m++){
   double *xp;              k2=anint[m][i]+(mint[m][i]/12.);
   double **gp, **gm;              if ((k2>=dateprev1) && (k2<=dateprev2)) {
   double ***gradg, ***trgradg;                if(agev[m][i]==0) agev[m][i]=iagemax+1;
   int theta;                if(agev[m][i]==1) agev[m][i]=iagemax+2;
                 if (s[m][i]>0 && s[m][i]<=nlstate) prop[s[m][i]][(int)agev[m][i]] += weight[i];
   varhe=ma3x(1,nlstate*2,1,nlstate*2,(int) bage, (int) fage);                if (m<lastpass) {
   xp=vector(1,npar);                  freq[s[m][i]][s[m+1][i]][(int)agev[m][i]] += weight[i];
   dnewm=matrix(1,nlstate*2,1,npar);                  freq[s[m][i]][s[m+1][i]][iagemax+3] += weight[i];
   doldm=matrix(1,nlstate*2,1,nlstate*2);                }
                  
   fprintf(ficreseij,"# Health expectancies\n");                if ((agev[m][i]>1) && (agev[m][i]< (iagemax+3))) {
   fprintf(ficreseij,"# Age");                  dateintsum=dateintsum+k2;
   for(i=1; i<=nlstate;i++)                  k2cpt++;
     for(j=1; j<=nlstate;j++)                }
       fprintf(ficreseij," %1d-%1d (SE)",i,j);              }
   fprintf(ficreseij,"\n");            }
           }
   if(estepm < stepm){        }
     printf ("Problem %d lower than %d\n",estepm, stepm);         
   }        fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);
   else  hstepm=estepm;    
   /* We compute the life expectancy from trapezoids spaced every estepm months        if  (cptcovn>0) {
    * This is mainly to measure the difference between two models: for example          fprintf(ficresp, "\n#********** Variable "); 
    * if stepm=24 months pijx are given only every 2 years and by summing them          for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
    * we are calculating an estimate of the Life Expectancy assuming a linear          fprintf(ficresp, "**********\n#");
    * progression inbetween and thus overestimating or underestimating according        }
    * to the curvature of the survival function. If, for the same date, we        for(i=1; i<=nlstate;i++) 
    * estimate the model with stepm=1 month, we can keep estepm to 24 months          fprintf(ficresp, " Age Prev(%d) N(%d) N",i,i);
    * to compare the new estimate of Life expectancy with the same linear        fprintf(ficresp, "\n");
    * hypothesis. A more precise result, taking into account a more precise        
    * curvature will be obtained if estepm is as small as stepm. */        for(i=iagemin; i <= iagemax+3; i++){
           if(i==iagemax+3){
   /* For example we decided to compute the life expectancy with the smallest unit */            fprintf(ficlog,"Total");
   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm.          }else{
      nhstepm is the number of hstepm from age to agelim            if(first==1){
      nstepm is the number of stepm from age to agelin.              first=0;
      Look at hpijx to understand the reason of that which relies in memory size              printf("See log file for details...\n");
      and note for a fixed period like estepm months */            }
   /* We decided (b) to get a life expectancy respecting the most precise curvature of the            fprintf(ficlog,"Age %d", i);
      survival function given by stepm (the optimization length). Unfortunately it          }
      means that if the survival funtion is printed only each two years of age and if          for(jk=1; jk <=nlstate ; jk++){
      you sum them up and add 1 year (area under the trapezoids) you won't get the same            for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
      results. So we changed our mind and took the option of the best precision.              pp[jk] += freq[jk][m][i]; 
   */          }
   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */          for(jk=1; jk <=nlstate ; jk++){
             for(m=-1, pos=0; m <=0 ; m++)
   agelim=AGESUP;              pos += freq[jk][m][i];
   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */            if(pp[jk]>=1.e-10){
     /* nhstepm age range expressed in number of stepm */              if(first==1){
     nstepm=(int) rint((agelim-age)*YEARM/stepm);              printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
     /* Typically if 20 years nstepm = 20*12/6=40 stepm */              }
     /* if (stepm >= YEARM) hstepm=1;*/              fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
     nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */            }else{
     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);              if(first==1)
     gradg=ma3x(0,nhstepm,1,npar,1,nlstate*2);                printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
     gp=matrix(0,nhstepm,1,nlstate*2);              fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
     gm=matrix(0,nhstepm,1,nlstate*2);            }
           }
     /* Computed by stepm unit matrices, product of hstepm matrices, stored  
        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */          for(jk=1; jk <=nlstate ; jk++){
     hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, ij);              for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)
                pp[jk] += freq[jk][m][i];
           }       
     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */          for(jk=1,pos=0,posprop=0; jk <=nlstate ; jk++){
             pos += pp[jk];
     /* Computing Variances of health expectancies */            posprop += prop[jk][i];
           }
      for(theta=1; theta <=npar; theta++){          for(jk=1; jk <=nlstate ; jk++){
       for(i=1; i<=npar; i++){            if(pos>=1.e-5){
         xp[i] = x[i] + (i==theta ?delti[theta]:0);              if(first==1)
       }                printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
       hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);                fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
              }else{
       cptj=0;              if(first==1)
       for(j=1; j<= nlstate; j++){                printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
         for(i=1; i<=nlstate; i++){              fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
           cptj=cptj+1;            }
           for(h=0, gp[h][cptj]=0.; h<=nhstepm-1; h++){            if( i <= iagemax){
             gp[h][cptj] = (p3mat[i][j][h]+p3mat[i][j][h+1])/2.;              if(pos>=1.e-5){
           }                fprintf(ficresp," %d %.5f %.0f %.0f",i,prop[jk][i]/posprop, prop[jk][i],posprop);
         }                probs[i][jk][j1]= pp[jk]/pos;
       }                /*printf("\ni=%d jk=%d j1=%d %.5f %.0f %.0f %f",i,jk,j1,pp[jk]/pos, pp[jk],pos,probs[i][jk][j1]);*/
                    }
                    else
       for(i=1; i<=npar; i++)                fprintf(ficresp," %d NaNq %.0f %.0f",i,prop[jk][i],posprop);
         xp[i] = x[i] - (i==theta ?delti[theta]:0);            }
       hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);            }
                
       cptj=0;          for(jk=-1; jk <=nlstate+ndeath; jk++)
       for(j=1; j<= nlstate; j++){            for(m=-1; m <=nlstate+ndeath; m++)
         for(i=1;i<=nlstate;i++){              if(freq[jk][m][i] !=0 ) {
           cptj=cptj+1;              if(first==1)
           for(h=0, gm[h][cptj]=0.; h<=nhstepm-1; h++){                printf(" %d%d=%.0f",jk,m,freq[jk][m][i]);
             gm[h][cptj] = (p3mat[i][j][h]+p3mat[i][j][h+1])/2.;                fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][i]);
           }              }
         }          if(i <= iagemax)
       }            fprintf(ficresp,"\n");
                if(first==1)
                printf("Others in log...\n");
           fprintf(ficlog,"\n");
       for(j=1; j<= nlstate*2; j++)        }
         for(h=0; h<=nhstepm-1; h++){      }
           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];    }
         }    dateintmean=dateintsum/k2cpt; 
    
      }    fclose(ficresp);
        free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);
 /* End theta */    free_vector(pp,1,nlstate);
     free_matrix(prop,1,nlstate,iagemin, iagemax+3);
      trgradg =ma3x(0,nhstepm,1,nlstate*2,1,npar);    /* End of Freq */
   }
      for(h=0; h<=nhstepm-1; h++)  
       for(j=1; j<=nlstate*2;j++)  /************ Prevalence ********************/
         for(theta=1; theta <=npar; theta++)  void prevalence(double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
         trgradg[h][j][theta]=gradg[h][theta][j];  {  
     /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
        in each health status at the date of interview (if between dateprev1 and dateprev2).
      for(i=1;i<=nlstate*2;i++)       We still use firstpass and lastpass as another selection.
       for(j=1;j<=nlstate*2;j++)    */
         varhe[i][j][(int)age] =0.;   
     int i, m, jk, k1, i1, j1, bool, z1,z2,j;
     for(h=0;h<=nhstepm-1;h++){    double ***freq; /* Frequencies */
       for(k=0;k<=nhstepm-1;k++){    double *pp, **prop;
         matprod2(dnewm,trgradg[h],1,nlstate*2,1,npar,1,npar,matcov);    double pos,posprop; 
         matprod2(doldm,dnewm,1,nlstate*2,1,npar,1,nlstate*2,gradg[k]);    double  y2; /* in fractional years */
         for(i=1;i<=nlstate*2;i++)    int iagemin, iagemax;
           for(j=1;j<=nlstate*2;j++)  
             varhe[i][j][(int)age] += doldm[i][j]*hf*hf;    iagemin= (int) agemin;
       }    iagemax= (int) agemax;
     }    /*pp=vector(1,nlstate);*/
     prop=matrix(1,nlstate,iagemin,iagemax+3); 
          /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
     /* Computing expectancies */    j1=0;
     for(i=1; i<=nlstate;i++)    
       for(j=1; j<=nlstate;j++)    j=cptcoveff;
         for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){    if (cptcovn<1) {j=1;ncodemax[1]=1;}
           eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;    
              for(k1=1; k1<=j;k1++){
 /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/      for(i1=1; i1<=ncodemax[k1];i1++){
         j1++;
         }        
         for (i=1; i<=nlstate; i++)  
     fprintf(ficreseij,"%3.0f",age );          for(m=iagemin; m <= iagemax+3; m++)
     cptj=0;            prop[i][m]=0.0;
     for(i=1; i<=nlstate;i++)       
       for(j=1; j<=nlstate;j++){        for (i=1; i<=imx; i++) { /* Each individual */
         cptj++;          bool=1;
         fprintf(ficreseij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[cptj][cptj][(int)age]) );          if  (cptcovn>0) {
       }            for (z1=1; z1<=cptcoveff; z1++) 
     fprintf(ficreseij,"\n");              if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtab[j1][z1]]) 
                    bool=0;
     free_matrix(gm,0,nhstepm,1,nlstate*2);          } 
     free_matrix(gp,0,nhstepm,1,nlstate*2);          if (bool==1) { 
     free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*2);            for(m=firstpass; m<=lastpass; m++){/* Other selection (we can limit to certain interviews*/
     free_ma3x(trgradg,0,nhstepm,1,nlstate*2,1,npar);              y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);              if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
   }                if(agev[m][i]==0) agev[m][i]=iagemax+1;
   free_vector(xp,1,npar);                if(agev[m][i]==1) agev[m][i]=iagemax+2;
   free_matrix(dnewm,1,nlstate*2,1,npar);                if((int)agev[m][i] <iagemin || (int)agev[m][i] >iagemax+3) printf("Error on individual =%d agev[m][i]=%f m=%d\n",i, agev[m][i],m); 
   free_matrix(doldm,1,nlstate*2,1,nlstate*2);                if (s[m][i]>0 && s[m][i]<=nlstate) { 
   free_ma3x(varhe,1,nlstate*2,1,nlstate*2,(int) bage, (int)fage);                  /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
 }                  prop[s[m][i]][(int)agev[m][i]] += weight[i];
                   prop[s[m][i]][iagemax+3] += weight[i]; 
 /************ Variance ******************/                } 
 void varevsij(char fileres[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij, int estepm)              }
 {            } /* end selection of waves */
   /* Variance of health expectancies */          }
   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/        }
   double **newm;        for(i=iagemin; i <= iagemax+3; i++){  
   double **dnewm,**doldm;          
   int i, j, nhstepm, hstepm, h, nstepm ;          for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
   int k, cptcode;            posprop += prop[jk][i]; 
   double *xp;          } 
   double **gp, **gm;  
   double ***gradg, ***trgradg;          for(jk=1; jk <=nlstate ; jk++){     
   double ***p3mat;            if( i <=  iagemax){ 
   double age,agelim, hf;              if(posprop>=1.e-5){ 
   int theta;                probs[i][jk][j1]= prop[jk][i]/posprop;
               } 
    fprintf(ficresvij,"# Covariances of life expectancies\n");            } 
   fprintf(ficresvij,"# Age");          }/* end jk */ 
   for(i=1; i<=nlstate;i++)        }/* end i */ 
     for(j=1; j<=nlstate;j++)      } /* end i1 */
       fprintf(ficresvij," Cov(e%1d, e%1d)",i,j);    } /* end k1 */
   fprintf(ficresvij,"\n");    
     /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
   xp=vector(1,npar);    /*free_vector(pp,1,nlstate);*/
   dnewm=matrix(1,nlstate,1,npar);    free_matrix(prop,1,nlstate, iagemin,iagemax+3);
   doldm=matrix(1,nlstate,1,nlstate);  }  /* End of prevalence */
    
   if(estepm < stepm){  /************* Waves Concatenation ***************/
     printf ("Problem %d lower than %d\n",estepm, stepm);  
   }  void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
   else  hstepm=estepm;    {
   /* For example we decided to compute the life expectancy with the smallest unit */    /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm.       Death is a valid wave (if date is known).
      nhstepm is the number of hstepm from age to agelim       mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
      nstepm is the number of stepm from age to agelin.       dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
      Look at hpijx to understand the reason of that which relies in memory size       and mw[mi+1][i]. dh depends on stepm.
      and note for a fixed period like k years */       */
   /* We decided (b) to get a life expectancy respecting the most precise curvature of the  
      survival function given by stepm (the optimization length). Unfortunately it    int i, mi, m;
      means that if the survival funtion is printed only each two years of age and if    /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
      you sum them up and add 1 year (area under the trapezoids) you won't get the same       double sum=0., jmean=0.;*/
      results. So we changed our mind and took the option of the best precision.    int first;
   */    int j, k=0,jk, ju, jl;
   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */    double sum=0.;
   agelim = AGESUP;    first=0;
   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */    jmin=1e+5;
     nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */    jmax=-1;
     nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */    jmean=0.;
     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);    for(i=1; i<=imx; i++){
     gradg=ma3x(0,nhstepm,1,npar,1,nlstate);      mi=0;
     gp=matrix(0,nhstepm,1,nlstate);      m=firstpass;
     gm=matrix(0,nhstepm,1,nlstate);      while(s[m][i] <= nlstate){
         if(s[m][i]>=1)
     for(theta=1; theta <=npar; theta++){          mw[++mi][i]=m;
       for(i=1; i<=npar; i++){ /* Computes gradient */        if(m >=lastpass)
         xp[i] = x[i] + (i==theta ?delti[theta]:0);          break;
       }        else
       hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);            m++;
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);      }/* end while */
       if (s[m][i] > nlstate){
       if (popbased==1) {        mi++;     /* Death is another wave */
         for(i=1; i<=nlstate;i++)        /* if(mi==0)  never been interviewed correctly before death */
           prlim[i][i]=probs[(int)age][i][ij];           /* Only death is a correct wave */
       }        mw[mi][i]=m;
        }
       for(j=1; j<= nlstate; j++){  
         for(h=0; h<=nhstepm; h++){      wav[i]=mi;
           for(i=1, gp[h][j]=0.;i<=nlstate;i++)      if(mi==0){
             gp[h][j] += prlim[i][i]*p3mat[i][j][h];        if(first==0){
         }          printf("Warning! None valid information for:%d line=%d (skipped) and may be others, see log file\n",num[i],i);
       }          first=1;
            }
       for(i=1; i<=npar; i++) /* Computes gradient */        if(first==1){
         xp[i] = x[i] - (i==theta ?delti[theta]:0);          fprintf(ficlog,"Warning! None valid information for:%d line=%d (skipped)\n",num[i],i);
       hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);          }
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);      } /* end mi==0 */
      } /* End individuals */
       if (popbased==1) {  
         for(i=1; i<=nlstate;i++)    for(i=1; i<=imx; i++){
           prlim[i][i]=probs[(int)age][i][ij];      for(mi=1; mi<wav[i];mi++){
       }        if (stepm <=0)
           dh[mi][i]=1;
       for(j=1; j<= nlstate; j++){        else{
         for(h=0; h<=nhstepm; h++){          if (s[mw[mi+1][i]][i] > nlstate) { /* A death */
           for(i=1, gm[h][j]=0.;i<=nlstate;i++)            if (agedc[i] < 2*AGESUP) {
             gm[h][j] += prlim[i][i]*p3mat[i][j][h];            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
         }            if(j==0) j=1;  /* Survives at least one month after exam */
       }            k=k+1;
             if (j >= jmax) jmax=j;
       for(j=1; j<= nlstate; j++)            if (j <= jmin) jmin=j;
         for(h=0; h<=nhstepm; h++){            sum=sum+j;
           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
         }            /*      printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
     } /* End theta */            if(j<0)printf("Error! Negative delay (%d to death) between waves %d and %d of individual %d at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
             }
     trgradg =ma3x(0,nhstepm,1,nlstate,1,npar);          }
           else{
     for(h=0; h<=nhstepm; h++)            j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
       for(j=1; j<=nlstate;j++)            /*      printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
         for(theta=1; theta <=npar; theta++)            k=k+1;
           trgradg[h][j][theta]=gradg[h][theta][j];            if (j >= jmax) jmax=j;
             else if (j <= jmin)jmin=j;
     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */            /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
     for(i=1;i<=nlstate;i++)            /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
       for(j=1;j<=nlstate;j++)            if(j<0)printf("Error! Negative delay (%d) between waves %d and %d of individual %d at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
         vareij[i][j][(int)age] =0.;            sum=sum+j;
           }
     for(h=0;h<=nhstepm;h++){          jk= j/stepm;
       for(k=0;k<=nhstepm;k++){          jl= j -jk*stepm;
         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);          ju= j -(jk+1)*stepm;
         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);          if(mle <=1){ 
         for(i=1;i<=nlstate;i++)            if(jl==0){
           for(j=1;j<=nlstate;j++)              dh[mi][i]=jk;
             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;              bh[mi][i]=0;
       }            }else{ /* We want a negative bias in order to only have interpolation ie
     }                    * at the price of an extra matrix product in likelihood */
               dh[mi][i]=jk+1;
     fprintf(ficresvij,"%.0f ",age );              bh[mi][i]=ju;
     for(i=1; i<=nlstate;i++)            }
       for(j=1; j<=nlstate;j++){          }else{
         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);            if(jl <= -ju){
       }              dh[mi][i]=jk;
     fprintf(ficresvij,"\n");              bh[mi][i]=jl;       /* bias is positive if real duration
     free_matrix(gp,0,nhstepm,1,nlstate);                                   * is higher than the multiple of stepm and negative otherwise.
     free_matrix(gm,0,nhstepm,1,nlstate);                                   */
     free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);            }
     free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);            else{
     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);              dh[mi][i]=jk+1;
   } /* End age */              bh[mi][i]=ju;
              }
   free_vector(xp,1,npar);            if(dh[mi][i]==0){
   free_matrix(doldm,1,nlstate,1,npar);              dh[mi][i]=1; /* At least one step */
   free_matrix(dnewm,1,nlstate,1,nlstate);              bh[mi][i]=ju; /* At least one step */
               /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
 }            }
           }
 /************ Variance of prevlim ******************/        } /* end if mle */
 void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij)      } /* end wave */
 {    }
   /* Variance of prevalence limit */    jmean=sum/k;
   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/    printf("Delay (in months) between two waves Min=%d Max=%d Mean=%f\n\n ",jmin, jmax,jmean);
   double **newm;    fprintf(ficlog,"Delay (in months) between two waves Min=%d Max=%d Mean=%f\n\n ",jmin, jmax,jmean);
   double **dnewm,**doldm;   }
   int i, j, nhstepm, hstepm;  
   int k, cptcode;  /*********** Tricode ****************************/
   double *xp;  void tricode(int *Tvar, int **nbcode, int imx)
   double *gp, *gm;  {
   double **gradg, **trgradg;    
   double age,agelim;    int Ndum[20],ij=1, k, j, i, maxncov=19;
   int theta;    int cptcode=0;
        cptcoveff=0; 
   fprintf(ficresvpl,"# Standard deviation of prevalences limit\n");   
   fprintf(ficresvpl,"# Age");    for (k=0; k<maxncov; k++) Ndum[k]=0;
   for(i=1; i<=nlstate;i++)    for (k=1; k<=7; k++) ncodemax[k]=0;
       fprintf(ficresvpl," %1d-%1d",i,i);  
   fprintf(ficresvpl,"\n");    for (j=1; j<=(cptcovn+2*cptcovprod); j++) {
       for (i=1; i<=imx; i++) { /*reads the data file to get the maximum 
   xp=vector(1,npar);                                 modality*/ 
   dnewm=matrix(1,nlstate,1,npar);        ij=(int)(covar[Tvar[j]][i]); /* ij is the modality of this individual*/
   doldm=matrix(1,nlstate,1,nlstate);        Ndum[ij]++; /*store the modality */
          /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
   hstepm=1*YEARM; /* Every year of age */        if (ij > cptcode) cptcode=ij; /* getting the maximum of covariable 
   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */                                         Tvar[j]. If V=sex and male is 0 and 
   agelim = AGESUP;                                         female is 1, then  cptcode=1.*/
   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */      }
     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */  
     if (stepm >= YEARM) hstepm=1;      for (i=0; i<=cptcode; i++) {
     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */        if(Ndum[i]!=0) ncodemax[j]++; /* Nomber of modalities of the j th covariates. In fact ncodemax[j]=2 (dichotom. variables) but it can be more */
     gradg=matrix(1,npar,1,nlstate);      }
     gp=vector(1,nlstate);  
     gm=vector(1,nlstate);      ij=1; 
       for (i=1; i<=ncodemax[j]; i++) {
     for(theta=1; theta <=npar; theta++){        for (k=0; k<= maxncov; k++) {
       for(i=1; i<=npar; i++){ /* Computes gradient */          if (Ndum[k] != 0) {
         xp[i] = x[i] + (i==theta ?delti[theta]:0);            nbcode[Tvar[j]][ij]=k; 
       }            /* store the modality in an array. k is a modality. If we have model=V1+V1*sex then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);            
       for(i=1;i<=nlstate;i++)            ij++;
         gp[i] = prlim[i][i];          }
              if (ij > ncodemax[j]) break; 
       for(i=1; i<=npar; i++) /* Computes gradient */        }  
         xp[i] = x[i] - (i==theta ?delti[theta]:0);      } 
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);    }  
       for(i=1;i<=nlstate;i++)  
         gm[i] = prlim[i][i];   for (k=0; k< maxncov; k++) Ndum[k]=0;
   
       for(i=1;i<=nlstate;i++)   for (i=1; i<=ncovmodel-2; i++) { 
         gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];     /* Listing of all covariables in staement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/
     } /* End theta */     ij=Tvar[i];
      Ndum[ij]++;
     trgradg =matrix(1,nlstate,1,npar);   }
   
     for(j=1; j<=nlstate;j++)   ij=1;
       for(theta=1; theta <=npar; theta++)   for (i=1; i<= maxncov; i++) {
         trgradg[j][theta]=gradg[theta][j];     if((Ndum[i]!=0) && (i<=ncovcol)){
        Tvaraff[ij]=i; /*For printing */
     for(i=1;i<=nlstate;i++)       ij++;
       varpl[i][(int)age] =0.;     }
     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);   }
     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);   
     for(i=1;i<=nlstate;i++)   cptcoveff=ij-1; /*Number of simple covariates*/
       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */  }
   
     fprintf(ficresvpl,"%.0f ",age );  /*********** Health Expectancies ****************/
     for(i=1; i<=nlstate;i++)  
       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));  void evsij(char fileres[], double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int ij, int estepm,double delti[],double **matcov )
     fprintf(ficresvpl,"\n");  
     free_vector(gp,1,nlstate);  {
     free_vector(gm,1,nlstate);    /* Health expectancies */
     free_matrix(gradg,1,npar,1,nlstate);    int i, j, nhstepm, hstepm, h, nstepm, k, cptj;
     free_matrix(trgradg,1,nlstate,1,npar);    double age, agelim, hf;
   } /* End age */    double ***p3mat,***varhe;
     double **dnewm,**doldm;
   free_vector(xp,1,npar);    double *xp;
   free_matrix(doldm,1,nlstate,1,npar);    double **gp, **gm;
   free_matrix(dnewm,1,nlstate,1,nlstate);    double ***gradg, ***trgradg;
     int theta;
 }  
     varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
 /************ Variance of one-step probabilities  ******************/    xp=vector(1,npar);
 void varprob(char fileres[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax)    dnewm=matrix(1,nlstate*nlstate,1,npar);
 {    doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
   int i, j, i1, k1, j1, z1;    
   int k=0, cptcode;    fprintf(ficreseij,"# Health expectancies\n");
   double **dnewm,**doldm;    fprintf(ficreseij,"# Age");
   double *xp;    for(i=1; i<=nlstate;i++)
   double *gp, *gm;      for(j=1; j<=nlstate;j++)
   double **gradg, **trgradg;        fprintf(ficreseij," %1d-%1d (SE)",i,j);
   double age,agelim, cov[NCOVMAX];    fprintf(ficreseij,"\n");
   int theta;  
   char fileresprob[FILENAMELENGTH];    if(estepm < stepm){
       printf ("Problem %d lower than %d\n",estepm, stepm);
   strcpy(fileresprob,"prob");    }
   strcat(fileresprob,fileres);    else  hstepm=estepm;   
   if((ficresprob=fopen(fileresprob,"w"))==NULL) {    /* We compute the life expectancy from trapezoids spaced every estepm months
     printf("Problem with resultfile: %s\n", fileresprob);     * This is mainly to measure the difference between two models: for example
   }     * if stepm=24 months pijx are given only every 2 years and by summing them
   printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);     * we are calculating an estimate of the Life Expectancy assuming a linear 
       * progression in between and thus overestimating or underestimating according
 fprintf(ficresprob,"#One-step probabilities and standard deviation in parentheses\n");     * to the curvature of the survival function. If, for the same date, we 
   fprintf(ficresprob,"# Age");     * estimate the model with stepm=1 month, we can keep estepm to 24 months
   for(i=1; i<=nlstate;i++)     * to compare the new estimate of Life expectancy with the same linear 
     for(j=1; j<=(nlstate+ndeath);j++)     * hypothesis. A more precise result, taking into account a more precise
       fprintf(ficresprob," p%1d-%1d (SE)",i,j);     * curvature will be obtained if estepm is as small as stepm. */
   
     /* For example we decided to compute the life expectancy with the smallest unit */
   fprintf(ficresprob,"\n");    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
        nhstepm is the number of hstepm from age to agelim 
        nstepm is the number of stepm from age to agelin. 
   xp=vector(1,npar);       Look at hpijx to understand the reason of that which relies in memory size
   dnewm=matrix(1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);       and note for a fixed period like estepm months */
   doldm=matrix(1,(nlstate+ndeath)*(nlstate+ndeath),1,(nlstate+ndeath)*(nlstate+ndeath));    /* We decided (b) to get a life expectancy respecting the most precise curvature of the
         survival function given by stepm (the optimization length). Unfortunately it
   cov[1]=1;       means that if the survival funtion is printed only each two years of age and if
   j=cptcoveff;       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
   if (cptcovn<1) {j=1;ncodemax[1]=1;}       results. So we changed our mind and took the option of the best precision.
   j1=0;    */
   for(k1=1; k1<=1;k1++){    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
     for(i1=1; i1<=ncodemax[k1];i1++){  
     j1++;    agelim=AGESUP;
     for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
     if  (cptcovn>0) {      /* nhstepm age range expressed in number of stepm */
       fprintf(ficresprob, "\n#********** Variable ");      nstepm=(int) rint((agelim-age)*YEARM/stepm); 
       for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);      /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
       fprintf(ficresprob, "**********\n#");      /* if (stepm >= YEARM) hstepm=1;*/
     }      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
          p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
       for (age=bage; age<=fage; age ++){      gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
         cov[2]=age;      gp=matrix(0,nhstepm,1,nlstate*nlstate);
         for (k=1; k<=cptcovn;k++) {      gm=matrix(0,nhstepm,1,nlstate*nlstate);
           cov[2+k]=nbcode[Tvar[k]][codtab[j1][Tvar[k]]];  
                /* Computed by stepm unit matrices, product of hstepm matrices, stored
         }         in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
         for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, ij);  
         for (k=1; k<=cptcovprod;k++)   
           cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];  
              hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
         gradg=matrix(1,npar,1,9);  
         trgradg=matrix(1,9,1,npar);      /* Computing Variances of health expectancies */
         gp=vector(1,(nlstate+ndeath)*(nlstate+ndeath));  
         gm=vector(1,(nlstate+ndeath)*(nlstate+ndeath));       for(theta=1; theta <=npar; theta++){
            for(i=1; i<=npar; i++){ 
         for(theta=1; theta <=npar; theta++){          xp[i] = x[i] + (i==theta ?delti[theta]:0);
           for(i=1; i<=npar; i++)        }
             xp[i] = x[i] + (i==theta ?delti[theta]:0);        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);  
              
           pmij(pmmij,cov,ncovmodel,xp,nlstate);        cptj=0;
                  for(j=1; j<= nlstate; j++){
           k=0;          for(i=1; i<=nlstate; i++){
           for(i=1; i<= (nlstate+ndeath); i++){            cptj=cptj+1;
             for(j=1; j<=(nlstate+ndeath);j++){            for(h=0, gp[h][cptj]=0.; h<=nhstepm-1; h++){
               k=k+1;              gp[h][cptj] = (p3mat[i][j][h]+p3mat[i][j][h+1])/2.;
               gp[k]=pmmij[i][j];            }
             }          }
           }        }
                 
           for(i=1; i<=npar; i++)       
             xp[i] = x[i] - (i==theta ?delti[theta]:0);        for(i=1; i<=npar; i++) 
              xp[i] = x[i] - (i==theta ?delti[theta]:0);
           pmij(pmmij,cov,ncovmodel,xp,nlstate);        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);  
           k=0;        
           for(i=1; i<=(nlstate+ndeath); i++){        cptj=0;
             for(j=1; j<=(nlstate+ndeath);j++){        for(j=1; j<= nlstate; j++){
               k=k+1;          for(i=1;i<=nlstate;i++){
               gm[k]=pmmij[i][j];            cptj=cptj+1;
             }            for(h=0, gm[h][cptj]=0.; h<=nhstepm-1; h++){
           }  
                    gm[h][cptj] = (p3mat[i][j][h]+p3mat[i][j][h+1])/2.;
           for(i=1; i<= (nlstate+ndeath)*(nlstate+ndeath); i++)            }
             gradg[theta][i]=(gp[i]-gm[i])/2./delti[theta];            }
         }        }
         for(j=1; j<= nlstate*nlstate; j++)
         for(j=1; j<=(nlstate+ndeath)*(nlstate+ndeath);j++)          for(h=0; h<=nhstepm-1; h++){
           for(theta=1; theta <=npar; theta++)            gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
             trgradg[j][theta]=gradg[theta][j];          }
               } 
         matprod2(dnewm,trgradg,1,9,1,npar,1,npar,matcov);     
         matprod2(doldm,dnewm,1,9,1,npar,1,9,gradg);  /* End theta */
          
         pmij(pmmij,cov,ncovmodel,x,nlstate);       trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
          
         k=0;       for(h=0; h<=nhstepm-1; h++)
         for(i=1; i<=(nlstate+ndeath); i++){        for(j=1; j<=nlstate*nlstate;j++)
           for(j=1; j<=(nlstate+ndeath);j++){          for(theta=1; theta <=npar; theta++)
             k=k+1;            trgradg[h][j][theta]=gradg[h][theta][j];
             gm[k]=pmmij[i][j];       
           }  
         }       for(i=1;i<=nlstate*nlstate;i++)
              for(j=1;j<=nlstate*nlstate;j++)
      /*printf("\n%d ",(int)age);          varhe[i][j][(int)age] =0.;
      for (i=1; i<=(nlstate+ndeath)*(nlstate+ndeath-1);i++){  
        printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));       printf("%d|",(int)age);fflush(stdout);
      }*/       fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
        for(h=0;h<=nhstepm-1;h++){
         fprintf(ficresprob,"\n%d ",(int)age);        for(k=0;k<=nhstepm-1;k++){
           matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
         for (i=1; i<=(nlstate+ndeath)*(nlstate+ndeath-1);i++)          matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
           fprintf(ficresprob,"%.3e (%.3e) ",gm[i],sqrt(doldm[i][i]));          for(i=1;i<=nlstate*nlstate;i++)
              for(j=1;j<=nlstate*nlstate;j++)
       }              varhe[i][j][(int)age] += doldm[i][j]*hf*hf;
     }        }
     free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));      }
     free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));      /* Computing expectancies */
     free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);      for(i=1; i<=nlstate;i++)
     free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);        for(j=1; j<=nlstate;j++)
   }          for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
   free_vector(xp,1,npar);            eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
   fclose(ficresprob);            
    /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
 }  
           }
 /******************* Printing html file ***********/  
 void printinghtml(char fileres[], char title[], char datafile[], int firstpass, \      fprintf(ficreseij,"%3.0f",age );
  int lastpass, int stepm, int weightopt, char model[],\      cptj=0;
  int imx,int jmin, int jmax, double jmeanint,char optionfile[], \      for(i=1; i<=nlstate;i++)
  char optionfilehtm[],char rfileres[], char optionfilegnuplot[],\        for(j=1; j<=nlstate;j++){
  char version[], int popforecast, int estepm ){          cptj++;
   int jj1, k1, i1, cpt;          fprintf(ficreseij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[cptj][cptj][(int)age]) );
   FILE *fichtm;        }
   /*char optionfilehtm[FILENAMELENGTH];*/      fprintf(ficreseij,"\n");
      
   strcpy(optionfilehtm,optionfile);      free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
   strcat(optionfilehtm,".htm");      free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
     printf("Problem with %s \n",optionfilehtm), exit(0);      free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
   }      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     }
  fprintf(fichtm,"<body> <font size=\"2\">%s </font> <hr size=\"2\" color=\"#EC5E5E\"> \n    printf("\n");
 Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=%s<br>\n    fprintf(ficlog,"\n");
 \n  
 Total number of observations=%d <br>\n    free_vector(xp,1,npar);
 Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n    free_matrix(dnewm,1,nlstate*nlstate,1,npar);
 <hr  size=\"2\" color=\"#EC5E5E\">    free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
  <ul><li>Outputs files<br>\n    free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n  }
  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n  
  - Observed prevalence in each state: <a href=\"p%s\">p%s</a> <br>\n  /************ Variance ******************/
  - Stationary prevalence in each state: <a href=\"pl%s\">pl%s</a> <br>\n  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav)
  - Transition probabilities: <a href=\"pij%s\">pij%s</a><br>\n  {
  - Life expectancies by age and initial health status (estepm=%2d months): <a href=\"e%s\">e%s</a> <br>\n",version,title,datafile,firstpass,lastpass,stepm, weightopt,model,imx,jmin,jmax,jmean,fileres,fileres,optionfilegnuplot,optionfilegnuplot,fileres,fileres,fileres,fileres,fileres,fileres,estepm,fileres,fileres);    /* Variance of health expectancies */
     /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
  fprintf(fichtm,"\n    /* double **newm;*/
  - Parameter file with estimated parameters and the covariance matrix: <a href=\"%s\">%s</a> <br>\n    double **dnewm,**doldm;
   - Variance of one-step probabilities: <a href=\"prob%s\">prob%s</a> <br>\n    double **dnewmp,**doldmp;
  - Variances of life expectancies by age and initial health status (estepm=%d months): <a href=\"v%s\">v%s</a><br>\n    int i, j, nhstepm, hstepm, h, nstepm ;
  - Health expectancies with their variances: <a href=\"t%s\">t%s</a> <br>\n    int k, cptcode;
  - Standard deviation of stationary prevalences: <a href=\"vpl%s\">vpl%s</a> <br>\n",rfileres,rfileres,fileres,fileres, estepm, fileres,fileres,fileres,fileres,fileres,fileres);    double *xp;
     double **gp, **gm;  /* for var eij */
  if(popforecast==1) fprintf(fichtm,"\n    double ***gradg, ***trgradg; /*for var eij */
  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n    double **gradgp, **trgradgp; /* for var p point j */
  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n    double *gpp, *gmp; /* for var p point j */
         <br>",fileres,fileres,fileres,fileres);    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
  else    double ***p3mat;
    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model);    double age,agelim, hf;
 fprintf(fichtm," <li>Graphs</li><p>");    double ***mobaverage;
     int theta;
  m=cptcoveff;    char digit[4];
  if (cptcovn < 1) {m=1;ncodemax[1]=1;}    char digitp[25];
   
  jj1=0;    char fileresprobmorprev[FILENAMELENGTH];
  for(k1=1; k1<=m;k1++){  
    for(i1=1; i1<=ncodemax[k1];i1++){    if(popbased==1){
        jj1++;      if(mobilav!=0)
        if (cptcovn > 0) {        strcpy(digitp,"-populbased-mobilav-");
          fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");      else strcpy(digitp,"-populbased-nomobil-");
          for (cpt=1; cpt<=cptcoveff;cpt++)    }
            fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtab[jj1][cpt]]);    else 
          fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");      strcpy(digitp,"-stablbased-");
        }  
        fprintf(fichtm,"<br>- Probabilities: pe%s%d.gif<br>    if (mobilav!=0) {
 <img src=\"pe%s%d.gif\">",strtok(optionfile, "."),jj1,strtok(optionfile, "."),jj1);          mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
        for(cpt=1; cpt<nlstate;cpt++){      if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){
          fprintf(fichtm,"<br>- Prevalence of disability : p%s%d%d.gif<br>        fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
 <img src=\"p%s%d%d.gif\">",strtok(optionfile, "."),cpt,jj1,strtok(optionfile, "."),cpt,jj1);        printf(" Error in movingaverage mobilav=%d\n",mobilav);
        }      }
     for(cpt=1; cpt<=nlstate;cpt++) {    }
        fprintf(fichtm,"<br>- Observed and stationary prevalence (with confident  
 interval) in state (%d): v%s%d%d.gif <br>    strcpy(fileresprobmorprev,"prmorprev"); 
 <img src=\"v%s%d%d.gif\">",cpt,strtok(optionfile, "."),cpt,jj1,strtok(optionfile, "."),cpt,jj1);      sprintf(digit,"%-d",ij);
      }    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
      for(cpt=1; cpt<=nlstate;cpt++) {    strcat(fileresprobmorprev,digit); /* Tvar to be done */
         fprintf(fichtm,"\n<br>- Health life expectancies by age and initial health state (%d): exp%s%d%d.gif <br>    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
 <img src=\"exp%s%d%d.gif\">",cpt,strtok(optionfile, "."),cpt,jj1,strtok(optionfile, "."),cpt,jj1);    strcat(fileresprobmorprev,fileres);
      }    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
      fprintf(fichtm,"\n<br>- Total life expectancy by age and      printf("Problem with resultfile: %s\n", fileresprobmorprev);
 health expectancies in states (1) and (2): e%s%d.gif<br>      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
 <img src=\"e%s%d.gif\">",strtok(optionfile, "."),jj1,strtok(optionfile, "."),jj1);    }
 fprintf(fichtm,"\n</body>");    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
    }    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
    }    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
 fclose(fichtm);    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
 }    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
       fprintf(ficresprobmorprev," p.%-d SE",j);
 /******************* Gnuplot file **************/      for(i=1; i<=nlstate;i++)
 void printinggnuplot(char fileres[],char optionfilefiname[],char optionfile[],char optionfilegnuplot[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
     }  
   int m,cpt,k1,i,k,j,jk,k2,k3,ij,l;    fprintf(ficresprobmorprev,"\n");
     if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) {
   strcpy(optionfilegnuplot,optionfilefiname);      printf("Problem with gnuplot file: %s\n", optionfilegnuplot);
   strcat(optionfilegnuplot,".gp.txt");      fprintf(ficlog,"Problem with gnuplot file: %s\n", optionfilegnuplot);
   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {      exit(0);
     printf("Problem with file %s",optionfilegnuplot);    }
   }    else{
       fprintf(ficgp,"\n# Routine varevsij");
 #ifdef windows    }
     fprintf(ficgp,"cd \"%s\" \n",pathc);    if((fichtm=fopen(optionfilehtm,"a"))==NULL) {
 #endif      printf("Problem with html file: %s\n", optionfilehtm);
 m=pow(2,cptcoveff);      fprintf(ficlog,"Problem with html file: %s\n", optionfilehtm);
        exit(0);
  /* 1eme*/    }
   for (cpt=1; cpt<= nlstate ; cpt ++) {    else{
    for (k1=1; k1<= m ; k1 ++) {      fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
       fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
      fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter gif small size 400,300\nplot [%.f:%.f] \"vpl%s\" every :::%d::%d u 1:2 \"\%%lf",ageminpar,fage,fileres,k1-1,k1-1);    }
     varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
 for (i=1; i<= nlstate ; i ++) {  
   if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are the stable prevalence in health states i\n");
   else fprintf(ficgp," \%%*lf (\%%*lf)");    fprintf(ficresvij,"# Age");
 }    for(i=1; i<=nlstate;i++)
     fprintf(ficgp,"\" t\"Stationary prevalence\" w l 0,\"vpl%s\" every :::%d::%d u 1:($2+2*$3) \"\%%lf",fileres,k1-1,k1-1);      for(j=1; j<=nlstate;j++)
     for (i=1; i<= nlstate ; i ++) {        fprintf(ficresvij," Cov(e%1d, e%1d)",i,j);
   if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");    fprintf(ficresvij,"\n");
   else fprintf(ficgp," \%%*lf (\%%*lf)");  
 }    xp=vector(1,npar);
   fprintf(ficgp,"\" t\"95\%% CI\" w l 1,\"vpl%s\" every :::%d::%d u 1:($2-2*$3) \"\%%lf",fileres,k1-1,k1-1);    dnewm=matrix(1,nlstate,1,npar);
      for (i=1; i<= nlstate ; i ++) {    doldm=matrix(1,nlstate,1,nlstate);
   if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
   else fprintf(ficgp," \%%*lf (\%%*lf)");    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
 }    
      fprintf(ficgp,"\" t\"\" w l 1,\"p%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence \" w l 2",fileres,k1-1,k1-1,2+4*(cpt-1));    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
     gpp=vector(nlstate+1,nlstate+ndeath);
 fprintf(ficgp,"\nset out \"v%s%d%d.gif\" \nreplot\n\n",strtok(optionfile, "."),cpt,k1);    gmp=vector(nlstate+1,nlstate+ndeath);
    }    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
   }    
   /*2 eme*/    if(estepm < stepm){
       printf ("Problem %d lower than %d\n",estepm, stepm);
   for (k1=1; k1<= m ; k1 ++) {    }
     fprintf(ficgp,"set ylabel \"Years\" \nset ter gif small size 400,300\nplot [%.f:%.f] ",ageminpar,fage);    else  hstepm=estepm;   
        /* For example we decided to compute the life expectancy with the smallest unit */
     for (i=1; i<= nlstate+1 ; i ++) {    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
       k=2*i;       nhstepm is the number of hstepm from age to agelim 
       fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:2 \"\%%lf",fileres,k1-1,k1-1);       nstepm is the number of stepm from age to agelin. 
       for (j=1; j<= nlstate+1 ; j ++) {       Look at hpijx to understand the reason of that which relies in memory size
   if (j==i) fprintf(ficgp," \%%lf (\%%lf)");       and note for a fixed period like k years */
   else fprintf(ficgp," \%%*lf (\%%*lf)");    /* We decided (b) to get a life expectancy respecting the most precise curvature of the
 }         survival function given by stepm (the optimization length). Unfortunately it
       if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l ,");       means that if the survival funtion is printed every two years of age and if
       else fprintf(ficgp,"\" t\"LE in state (%d)\" w l ,",i-1);       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
     fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:($2-$3*2) \"\%%lf",fileres,k1-1,k1-1);       results. So we changed our mind and took the option of the best precision.
       for (j=1; j<= nlstate+1 ; j ++) {    */
         if (j==i) fprintf(ficgp," \%%lf (\%%lf)");    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
         else fprintf(ficgp," \%%*lf (\%%*lf)");    agelim = AGESUP;
 }      for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
       fprintf(ficgp,"\" t\"\" w l 0,");      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
      fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:($2+$3*2) \"\%%lf",fileres,k1-1,k1-1);      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
       for (j=1; j<= nlstate+1 ; j ++) {      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
   if (j==i) fprintf(ficgp," \%%lf (\%%lf)");      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
   else fprintf(ficgp," \%%*lf (\%%*lf)");      gp=matrix(0,nhstepm,1,nlstate);
 }        gm=matrix(0,nhstepm,1,nlstate);
       if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l 0");  
       else fprintf(ficgp,"\" t\"\" w l 0,");  
     }      for(theta=1; theta <=npar; theta++){
     fprintf(ficgp,"\nset out \"e%s%d.gif\" \nreplot\n\n",strtok(optionfile, "."),k1);        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
   }          xp[i] = x[i] + (i==theta ?delti[theta]:0);
          }
   /*3eme*/        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);  
         prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);
   for (k1=1; k1<= m ; k1 ++) {  
     for (cpt=1; cpt<= nlstate ; cpt ++) {        if (popbased==1) {
       k=2+nlstate*(2*cpt-2);          if(mobilav ==0){
       fprintf(ficgp,"set ter gif small size 400,300\nplot [%.f:%.f] \"e%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,fileres,k1-1,k1-1,k,cpt);            for(i=1; i<=nlstate;i++)
       /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);              prlim[i][i]=probs[(int)age][i][ij];
  for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");          }else{ /* mobilav */ 
 fprintf(ficgp,"\" t \"e%d1\" w l",cpt);            for(i=1; i<=nlstate;i++)
 fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);              prlim[i][i]=mobaverage[(int)age][i][ij];
  for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");          }
 fprintf(ficgp,"\" t \"e%d1\" w l",cpt);        }
     
 */        for(j=1; j<= nlstate; j++){
       for (i=1; i< nlstate ; i ++) {          for(h=0; h<=nhstepm; h++){
         fprintf(ficgp," ,\"e%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",fileres,k1-1,k1-1,k+2*i,cpt,i+1);            for(i=1, gp[h][j]=0.;i<=nlstate;i++)
               gp[h][j] += prlim[i][i]*p3mat[i][j][h];
       }          }
       fprintf(ficgp,"\nset out \"exp%s%d%d.gif\" \nreplot\n\n",strtok(optionfile, "."),cpt,k1);        }
     }        /* This for computing probability of death (h=1 means
     }           computed over hstepm matrices product = hstepm*stepm months) 
             as a weighted average of prlim.
   /* CV preval stat */        */
     for (k1=1; k1<= m ; k1 ++) {        for(j=nlstate+1;j<=nlstate+ndeath;j++){
     for (cpt=1; cpt<nlstate ; cpt ++) {          for(i=1,gpp[j]=0.; i<= nlstate; i++)
       k=3;            gpp[j] += prlim[i][i]*p3mat[i][j][1];
       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter gif small size 400,300\nplot [%.f:%.f] \"pij%s\" u ($1==%d ? ($3):1/0):($%d/($%d",ageminpar,agemaxpar,fileres,k1,k+cpt+1,k+1);        }    
         /* end probability of death */
       for (i=1; i< nlstate ; i ++)  
         fprintf(ficgp,"+$%d",k+i+1);        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
       fprintf(ficgp,")) t\"prev(%d,%d)\" w l",cpt,cpt+1);          xp[i] = x[i] - (i==theta ?delti[theta]:0);
              hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);  
       l=3+(nlstate+ndeath)*cpt;        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);
       fprintf(ficgp,",\"pij%s\" u ($1==%d ? ($3):1/0):($%d/($%d",fileres,k1,l+cpt+1,l+1);   
       for (i=1; i< nlstate ; i ++) {        if (popbased==1) {
         l=3+(nlstate+ndeath)*cpt;          if(mobilav ==0){
         fprintf(ficgp,"+$%d",l+i+1);            for(i=1; i<=nlstate;i++)
       }              prlim[i][i]=probs[(int)age][i][ij];
       fprintf(ficgp,")) t\"prev(%d,%d)\" w l\n",cpt+1,cpt+1);            }else{ /* mobilav */ 
       fprintf(ficgp,"set out \"p%s%d%d.gif\" \nreplot\n\n",strtok(optionfile, "."),cpt,k1);            for(i=1; i<=nlstate;i++)
     }              prlim[i][i]=mobaverage[(int)age][i][ij];
   }            }
          }
   /* proba elementaires */  
    for(i=1,jk=1; i <=nlstate; i++){        for(j=1; j<= nlstate; j++){
     for(k=1; k <=(nlstate+ndeath); k++){          for(h=0; h<=nhstepm; h++){
       if (k != i) {            for(i=1, gm[h][j]=0.;i<=nlstate;i++)
         for(j=1; j <=ncovmodel; j++){              gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                  }
           fprintf(ficgp,"p%d=%f ",jk,p[jk]);        }
           jk++;        /* This for computing probability of death (h=1 means
           fprintf(ficgp,"\n");           computed over hstepm matrices product = hstepm*stepm months) 
         }           as a weighted average of prlim.
       }        */
     }        for(j=nlstate+1;j<=nlstate+ndeath;j++){
     }          for(i=1,gmp[j]=0.; i<= nlstate; i++)
            gmp[j] += prlim[i][i]*p3mat[i][j][1];
     for(jk=1; jk <=m; jk++) {        }    
   fprintf(ficgp,"\nset ter gif small size 400,300\nset log y\nplot  [%.f:%.f] ",ageminpar,agemaxpar);        /* end probability of death */
    i=1;  
    for(k2=1; k2<=nlstate; k2++) {        for(j=1; j<= nlstate; j++) /* vareij */
      k3=i;          for(h=0; h<=nhstepm; h++){
      for(k=1; k<=(nlstate+ndeath); k++) {            gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
        if (k != k2){          }
         fprintf(ficgp," exp(p%d+p%d*x",i,i+1);  
 ij=1;        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
         for(j=3; j <=ncovmodel; j++) {          gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
           if(((j-2)==Tage[ij]) &&(ij <=cptcovage)) {        }
             fprintf(ficgp,"+p%d*%d*x",i+j-1,nbcode[Tvar[j-2]][codtab[jk][Tvar[j-2]]]);  
             ij++;      } /* End theta */
           }  
           else      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
           fprintf(ficgp,"+p%d*%d",i+j-1,nbcode[Tvar[j-2]][codtab[jk][j-2]]);  
         }      for(h=0; h<=nhstepm; h++) /* veij */
           fprintf(ficgp,")/(1");        for(j=1; j<=nlstate;j++)
                  for(theta=1; theta <=npar; theta++)
         for(k1=1; k1 <=nlstate; k1++){              trgradg[h][j][theta]=gradg[h][theta][j];
           fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);  
 ij=1;      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
           for(j=3; j <=ncovmodel; j++){        for(theta=1; theta <=npar; theta++)
           if(((j-2)==Tage[ij]) &&(ij <=cptcovage)) {          trgradgp[j][theta]=gradgp[theta][j];
             fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2,nbcode[Tvar[j-2]][codtab[jk][Tvar[j-2]]]);    
             ij++;  
           }      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
           else      for(i=1;i<=nlstate;i++)
             fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2,nbcode[Tvar[j-2]][codtab[jk][j-2]]);        for(j=1;j<=nlstate;j++)
           }          vareij[i][j][(int)age] =0.;
           fprintf(ficgp,")");  
         }      for(h=0;h<=nhstepm;h++){
         fprintf(ficgp,") t \"p%d%d\" ", k2,k);        for(k=0;k<=nhstepm;k++){
         if ((k+k2)!= (nlstate*2+ndeath)) fprintf(ficgp,",");          matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
         i=i+ncovmodel;          matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
        }          for(i=1;i<=nlstate;i++)
      }            for(j=1;j<=nlstate;j++)
    }              vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
    fprintf(ficgp,"\nset out \"pe%s%d.gif\" \nreplot\n\n",strtok(optionfile, "."),jk);        }
    }      }
        
   fclose(ficgp);      /* pptj */
 }  /* end gnuplot */      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
       matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
       for(j=nlstate+1;j<=nlstate+ndeath;j++)
 /*************** Moving average **************/        for(i=nlstate+1;i<=nlstate+ndeath;i++)
 void movingaverage(double agedeb, double fage,double ageminpar, double ***mobaverage){          varppt[j][i]=doldmp[j][i];
       /* end ppptj */
   int i, cpt, cptcod;      /*  x centered again */
     for (agedeb=ageminpar; agedeb<=fage; agedeb++)      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij);  
       for (i=1; i<=nlstate;i++)      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ij);
         for (cptcod=1;cptcod<=ncodemax[cptcov];cptcod++)   
           mobaverage[(int)agedeb][i][cptcod]=0.;      if (popbased==1) {
            if(mobilav ==0){
     for (agedeb=ageminpar+4; agedeb<=fage; agedeb++){          for(i=1; i<=nlstate;i++)
       for (i=1; i<=nlstate;i++){            prlim[i][i]=probs[(int)age][i][ij];
         for (cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){        }else{ /* mobilav */ 
           for (cpt=0;cpt<=4;cpt++){          for(i=1; i<=nlstate;i++)
             mobaverage[(int)agedeb-2][i][cptcod]=mobaverage[(int)agedeb-2][i][cptcod]+probs[(int)agedeb-cpt][i][cptcod];            prlim[i][i]=mobaverage[(int)age][i][ij];
           }        }
           mobaverage[(int)agedeb-2][i][cptcod]=mobaverage[(int)agedeb-2][i][cptcod]/5;      }
         }               
       }      /* This for computing probability of death (h=1 means
     }         computed over hstepm (estepm) matrices product = hstepm*stepm months) 
             as a weighted average of prlim.
 }      */
       for(j=nlstate+1;j<=nlstate+ndeath;j++){
         for(i=1,gmp[j]=0.;i<= nlstate; i++) 
 /************** Forecasting ******************/          gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
 prevforecast(char fileres[], double anproj1,double mproj1,double jproj1,double ageminpar, double agemax,double dateprev1, double dateprev2, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anproj2,double p[], int i2){      }    
        /* end probability of death */
   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h;  
   int *popage;      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
   double calagedate, agelim, kk1, kk2, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
   double *popeffectif,*popcount;        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
   double ***p3mat;        for(i=1; i<=nlstate;i++){
   char fileresf[FILENAMELENGTH];          fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
         }
  agelim=AGESUP;      } 
 calagedate=(anproj1+mproj1/12.+jproj1/365.-dateintmean)*YEARM;      fprintf(ficresprobmorprev,"\n");
   
   prevalence(ageminpar, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax,mint,anint,dateprev1,dateprev2, calagedate);      fprintf(ficresvij,"%.0f ",age );
        for(i=1; i<=nlstate;i++)
          for(j=1; j<=nlstate;j++){
   strcpy(fileresf,"f");          fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
   strcat(fileresf,fileres);        }
   if((ficresf=fopen(fileresf,"w"))==NULL) {      fprintf(ficresvij,"\n");
     printf("Problem with forecast resultfile: %s\n", fileresf);      free_matrix(gp,0,nhstepm,1,nlstate);
   }      free_matrix(gm,0,nhstepm,1,nlstate);
   printf("Computing forecasting: result on file '%s' \n", fileresf);      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
       free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
   if (cptcoveff==0) ncodemax[cptcoveff]=1;      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     } /* End age */
   if (mobilav==1) {    free_vector(gpp,nlstate+1,nlstate+ndeath);
     mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);    free_vector(gmp,nlstate+1,nlstate+ndeath);
     movingaverage(agedeb, fage, ageminpar, mobaverage);    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
   }    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
     fprintf(ficgp,"\nset noparametric;set nolabel; set ter png small;set size 0.65, 0.65");
   stepsize=(int) (stepm+YEARM-1)/YEARM;    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
   if (stepm<=12) stepsize=1;    fprintf(ficgp,"\n set log y; set nolog x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
   agelim=AGESUP;  /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
   hstepm=1;    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l 1 ",fileresprobmorprev);
   hstepm=hstepm/stepm;    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95\%% interval\" w l 2 ",fileresprobmorprev);
   yp1=modf(dateintmean,&yp);    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l 2 ",fileresprobmorprev);
   anprojmean=yp;    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",fileresprobmorprev,fileresprobmorprev);
   yp2=modf((yp1*12),&yp);    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"varmuptjgr%s%s%s.png\"> <br>\n", estepm,digitp,optionfilefiname,digit);
   mprojmean=yp;    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.png\"> <br>\n", stepm,YEARM,digitp,digit);
   yp1=modf((yp2*30.5),&yp);  */
   jprojmean=yp;    fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.png\";replot;",digitp,optionfilefiname,digit);
   if(jprojmean==0) jprojmean=1;  
   if(mprojmean==0) jprojmean=1;    free_vector(xp,1,npar);
      free_matrix(doldm,1,nlstate,1,nlstate);
   fprintf(ficresf,"# Estimated date of observed prevalence: %.lf/%.lf/%.lf ",jprojmean,mprojmean,anprojmean);    free_matrix(dnewm,1,nlstate,1,npar);
      free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
   for(cptcov=1;cptcov<=i2;cptcov++){    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
       k=k+1;    if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       fprintf(ficresf,"\n#******");    fclose(ficresprobmorprev);
       for(j=1;j<=cptcoveff;j++) {    fclose(ficgp);
         fprintf(ficresf," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);    fclose(fichtm);
       }  }  
       fprintf(ficresf,"******\n");  
       fprintf(ficresf,"# StartingAge FinalAge");  /************ Variance of prevlim ******************/
       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficresf," P.%d",j);  void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij)
        {
          /* Variance of prevalence limit */
       for (cpt=0; cpt<=(anproj2-anproj1);cpt++) {    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
         fprintf(ficresf,"\n");    double **newm;
         fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+cpt);      double **dnewm,**doldm;
     int i, j, nhstepm, hstepm;
         for (agedeb=(fage-((int)calagedate %12/12.)); agedeb>=(ageminpar-((int)calagedate %12)/12.); agedeb--){    int k, cptcode;
           nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);    double *xp;
           nhstepm = nhstepm/hstepm;    double *gp, *gm;
              double **gradg, **trgradg;
           p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);    double age,agelim;
           oldm=oldms;savm=savms;    int theta;
           hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);       
            fprintf(ficresvpl,"# Standard deviation of stable prevalences \n");
           for (h=0; h<=nhstepm; h++){    fprintf(ficresvpl,"# Age");
             if (h==(int) (calagedate+YEARM*cpt)) {    for(i=1; i<=nlstate;i++)
               fprintf(ficresf,"\n %.f %.f ",anproj1+cpt,agedeb+h*hstepm/YEARM*stepm);        fprintf(ficresvpl," %1d-%1d",i,i);
             }    fprintf(ficresvpl,"\n");
             for(j=1; j<=nlstate+ndeath;j++) {  
               kk1=0.;kk2=0;    xp=vector(1,npar);
               for(i=1; i<=nlstate;i++) {                  dnewm=matrix(1,nlstate,1,npar);
                 if (mobilav==1)    doldm=matrix(1,nlstate,1,nlstate);
                   kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod];    
                 else {    hstepm=1*YEARM; /* Every year of age */
                   kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod];    hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                 }    agelim = AGESUP;
                    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
               }      nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
               if (h==(int)(calagedate+12*cpt)){      if (stepm >= YEARM) hstepm=1;
                 fprintf(ficresf," %.3f", kk1);      nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                              gradg=matrix(1,npar,1,nlstate);
               }      gp=vector(1,nlstate);
             }      gm=vector(1,nlstate);
           }  
           free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);      for(theta=1; theta <=npar; theta++){
         }        for(i=1; i<=npar; i++){ /* Computes gradient */
       }          xp[i] = x[i] + (i==theta ?delti[theta]:0);
     }        }
   }        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);
                for(i=1;i<=nlstate;i++)
   if (mobilav==1) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);          gp[i] = prlim[i][i];
       
   fclose(ficresf);        for(i=1; i<=npar; i++) /* Computes gradient */
 }          xp[i] = x[i] - (i==theta ?delti[theta]:0);
 /************** Forecasting ******************/        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);
 populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){        for(i=1;i<=nlstate;i++)
            gm[i] = prlim[i][i];
   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h;  
   int *popage;        for(i=1;i<=nlstate;i++)
   double calagedate, agelim, kk1, kk2, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;          gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
   double *popeffectif,*popcount;      } /* End theta */
   double ***p3mat,***tabpop,***tabpopprev;  
   char filerespop[FILENAMELENGTH];      trgradg =matrix(1,nlstate,1,npar);
   
   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);      for(j=1; j<=nlstate;j++)
   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);        for(theta=1; theta <=npar; theta++)
   agelim=AGESUP;          trgradg[j][theta]=gradg[theta][j];
   calagedate=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM;  
        for(i=1;i<=nlstate;i++)
   prevalence(ageminpar, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax,mint,anint,dateprev1,dateprev2, calagedate);        varpl[i][(int)age] =0.;
        matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
        matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
   strcpy(filerespop,"pop");      for(i=1;i<=nlstate;i++)
   strcat(filerespop,fileres);        varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
   if((ficrespop=fopen(filerespop,"w"))==NULL) {  
     printf("Problem with forecast resultfile: %s\n", filerespop);      fprintf(ficresvpl,"%.0f ",age );
   }      for(i=1; i<=nlstate;i++)
   printf("Computing forecasting: result on file '%s' \n", filerespop);        fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
       fprintf(ficresvpl,"\n");
   if (cptcoveff==0) ncodemax[cptcoveff]=1;      free_vector(gp,1,nlstate);
       free_vector(gm,1,nlstate);
   if (mobilav==1) {      free_matrix(gradg,1,npar,1,nlstate);
     mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);      free_matrix(trgradg,1,nlstate,1,npar);
     movingaverage(agedeb, fage, ageminpar, mobaverage);    } /* End age */
   }  
     free_vector(xp,1,npar);
   stepsize=(int) (stepm+YEARM-1)/YEARM;    free_matrix(doldm,1,nlstate,1,npar);
   if (stepm<=12) stepsize=1;    free_matrix(dnewm,1,nlstate,1,nlstate);
    
   agelim=AGESUP;  }
    
   hstepm=1;  /************ Variance of one-step probabilities  ******************/
   hstepm=hstepm/stepm;  void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax)
    {
   if (popforecast==1) {    int i, j=0,  i1, k1, l1, t, tj;
     if((ficpop=fopen(popfile,"r"))==NULL) {    int k2, l2, j1,  z1;
       printf("Problem with population file : %s\n",popfile);exit(0);    int k=0,l, cptcode;
     }    int first=1, first1;
     popage=ivector(0,AGESUP);    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
     popeffectif=vector(0,AGESUP);    double **dnewm,**doldm;
     popcount=vector(0,AGESUP);    double *xp;
        double *gp, *gm;
     i=1;      double **gradg, **trgradg;
     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1;    double **mu;
        double age,agelim, cov[NCOVMAX];
     imx=i;    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i];    int theta;
   }    char fileresprob[FILENAMELENGTH];
     char fileresprobcov[FILENAMELENGTH];
   for(cptcov=1;cptcov<=i2;cptcov++){    char fileresprobcor[FILENAMELENGTH];
    for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){  
       k=k+1;    double ***varpij;
       fprintf(ficrespop,"\n#******");  
       for(j=1;j<=cptcoveff;j++) {    strcpy(fileresprob,"prob"); 
         fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);    strcat(fileresprob,fileres);
       }    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
       fprintf(ficrespop,"******\n");      printf("Problem with resultfile: %s\n", fileresprob);
       fprintf(ficrespop,"# Age");      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j);    }
       if (popforecast==1)  fprintf(ficrespop," [Population]");    strcpy(fileresprobcov,"probcov"); 
          strcat(fileresprobcov,fileres);
       for (cpt=0; cpt<=0;cpt++) {    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
         fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);        printf("Problem with resultfile: %s\n", fileresprobcov);
              fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
         for (agedeb=(fage-((int)calagedate %12/12.)); agedeb>=(ageminpar-((int)calagedate %12)/12.); agedeb--){    }
           nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);    strcpy(fileresprobcor,"probcor"); 
           nhstepm = nhstepm/hstepm;    strcat(fileresprobcor,fileres);
              if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
           p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);      printf("Problem with resultfile: %s\n", fileresprobcor);
           oldm=oldms;savm=savms;      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
           hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);      }
            printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
           for (h=0; h<=nhstepm; h++){    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
             if (h==(int) (calagedate+YEARM*cpt)) {    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
               fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm);    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
             }    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
             for(j=1; j<=nlstate+ndeath;j++) {    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
               kk1=0.;kk2=0;    
               for(i=1; i<=nlstate;i++) {                  fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                 if (mobilav==1)    fprintf(ficresprob,"# Age");
                   kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod];    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                 else {    fprintf(ficresprobcov,"# Age");
                   kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod];    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                 }    fprintf(ficresprobcov,"# Age");
               }  
               if (h==(int)(calagedate+12*cpt)){  
                 tabpop[(int)(agedeb)][j][cptcod]=kk1;    for(i=1; i<=nlstate;i++)
                   /*fprintf(ficrespop," %.3f", kk1);      for(j=1; j<=(nlstate+ndeath);j++){
                     if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*/        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
               }        fprintf(ficresprobcov," p%1d-%1d ",i,j);
             }        fprintf(ficresprobcor," p%1d-%1d ",i,j);
             for(i=1; i<=nlstate;i++){      }  
               kk1=0.;   /* fprintf(ficresprob,"\n");
                 for(j=1; j<=nlstate;j++){    fprintf(ficresprobcov,"\n");
                   kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];    fprintf(ficresprobcor,"\n");
                 }   */
                   tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedate+12*cpt)*hstepm/YEARM*stepm-1)];   xp=vector(1,npar);
             }    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
     doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
             if (h==(int)(calagedate+12*cpt)) for(j=1; j<=nlstate;j++)    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
               fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]);    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
           }    first=1;
           free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);    if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) {
         }      printf("Problem with gnuplot file: %s\n", optionfilegnuplot);
       }      fprintf(ficlog,"Problem with gnuplot file: %s\n", optionfilegnuplot);
        exit(0);
   /******/    }
     else{
       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {      fprintf(ficgp,"\n# Routine varprob");
         fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);      }
         for (agedeb=(fage-((int)calagedate %12/12.)); agedeb>=(ageminpar-((int)calagedate %12)/12.); agedeb--){    if((fichtm=fopen(optionfilehtm,"a"))==NULL) {
           nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);      printf("Problem with html file: %s\n", optionfilehtm);
           nhstepm = nhstepm/hstepm;      fprintf(ficlog,"Problem with html file: %s\n", optionfilehtm);
                exit(0);
           p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);    }
           oldm=oldms;savm=savms;    else{
           hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);        fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
           for (h=0; h<=nhstepm; h++){      fprintf(fichtm,"\n");
             if (h==(int) (calagedate+YEARM*cpt)) {  
               fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm);      fprintf(fichtm,"\n<li><h4> Computing matrix of variance-covariance of step probabilities</h4></li>\n");
             }      fprintf(fichtm,"\nWe have drawn ellipsoids of confidence around the p<inf>ij</inf>, p<inf>kl</inf> to understand the covariance between two incidences. They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
             for(j=1; j<=nlstate+ndeath;j++) {      fprintf(fichtm,"\n<br> We have drawn x'cov<sup>-1</sup>x = 4 where x is the column vector (pij,pkl). It means that if pij and pkl where uncorrelated the (2X2) matrix would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 standard deviations wide on each axis. <br> When both incidences are correlated we diagonalised the inverse of the covariance matrix and made the appropriate rotation.<br> \n");
               kk1=0.;kk2=0;  
               for(i=1; i<=nlstate;i++) {                  }
                 kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];      
               }    cov[1]=1;
               if (h==(int)(calagedate+12*cpt)) fprintf(ficresf," %15.2f", kk1);    tj=cptcoveff;
             }    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
           }    j1=0;
           free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);    for(t=1; t<=tj;t++){
         }      for(i1=1; i1<=ncodemax[t];i1++){ 
       }        j1++;
    }        if  (cptcovn>0) {
   }          fprintf(ficresprob, "\n#********** Variable "); 
            for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
   if (mobilav==1) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);          fprintf(ficresprob, "**********\n#\n");
           fprintf(ficresprobcov, "\n#********** Variable "); 
   if (popforecast==1) {          for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
     free_ivector(popage,0,AGESUP);          fprintf(ficresprobcov, "**********\n#\n");
     free_vector(popeffectif,0,AGESUP);          
     free_vector(popcount,0,AGESUP);          fprintf(ficgp, "\n#********** Variable "); 
   }          for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);          fprintf(ficgp, "**********\n#\n");
   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);          
   fclose(ficrespop);          
 }          fprintf(fichtm, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
 /***********************************************/          fprintf(fichtm, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
 /**************** Main Program *****************/          
 /***********************************************/          fprintf(ficresprobcor, "\n#********** Variable ");    
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);
 int main(int argc, char *argv[])          fprintf(ficresprobcor, "**********\n#");    
 {        }
         
   int i,j, k, n=MAXN,iter,m,size,cptcode, cptcod;        for (age=bage; age<=fage; age ++){ 
   double agedeb, agefin,hf;          cov[2]=age;
   double ageminpar=1.e20,agemin=1.e20, agemaxpar=-1.e20, agemax=-1.e20;          for (k=1; k<=cptcovn;k++) {
             cov[2+k]=nbcode[Tvar[k]][codtab[j1][Tvar[k]]];
   double fret;          }
   double **xi,tmp,delta;          for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];
           for (k=1; k<=cptcovprod;k++)
   double dum; /* Dummy variable */            cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];
   double ***p3mat;          
   int *indx;          gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
   char line[MAXLINE], linepar[MAXLINE];          trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
   char title[MAXLINE];          gp=vector(1,(nlstate)*(nlstate+ndeath));
   char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH];          gm=vector(1,(nlstate)*(nlstate+ndeath));
   char optionfilext[10], optionfilefiname[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilegnuplot[FILENAMELENGTH], plotcmd[FILENAMELENGTH];      
            for(theta=1; theta <=npar; theta++){
   char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];            for(i=1; i<=npar; i++)
               xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
   char filerest[FILENAMELENGTH];            
   char fileregp[FILENAMELENGTH];            pmij(pmmij,cov,ncovmodel,xp,nlstate);
   char popfile[FILENAMELENGTH];            
   char path[80],pathc[80],pathcd[80],pathtot[80],model[20];            k=0;
   int firstobs=1, lastobs=10;            for(i=1; i<= (nlstate); i++){
   int sdeb, sfin; /* Status at beginning and end */              for(j=1; j<=(nlstate+ndeath);j++){
   int c,  h , cpt,l;                k=k+1;
   int ju,jl, mi;                gp[k]=pmmij[i][j];
   int i1,j1, k1,k2,k3,jk,aa,bb, stepsize, ij;              }
   int jnais,jdc,jint4,jint1,jint2,jint3,**outcome,**adl,*tab;            }
   int mobilav=0,popforecast=0;            
   int hstepm, nhstepm;            for(i=1; i<=npar; i++)
   double jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,jpyram, mpyram,anpyram,jpyram1, mpyram1,anpyram1, calagedate;              xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
       
   double bage, fage, age, agelim, agebase;            pmij(pmmij,cov,ncovmodel,xp,nlstate);
   double ftolpl=FTOL;            k=0;
   double **prlim;            for(i=1; i<=(nlstate); i++){
   double *severity;              for(j=1; j<=(nlstate+ndeath);j++){
   double ***param; /* Matrix of parameters */                k=k+1;
   double  *p;                gm[k]=pmmij[i][j];
   double **matcov; /* Matrix of covariance */              }
   double ***delti3; /* Scale */            }
   double *delti; /* Scale */       
   double ***eij, ***vareij;            for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
   double **varpl; /* Variances of prevalence limits by age */              gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
   double *epj, vepp;          }
   double kk1, kk2;  
   double dateprev1, dateprev2,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2;          for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
              for(theta=1; theta <=npar; theta++)
               trgradg[j][theta]=gradg[theta][j];
   char version[80]="Imach version 0.8a, May 2002, INED-EUROREVES ";          
   char *alph[]={"a","a","b","c","d","e"}, str[4];          matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
           matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
           free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
   char z[1]="c", occ;          free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
 #include <sys/time.h>          free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
 #include <time.h>          free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
   char stra[80], strb[80], strc[80], strd[80],stre[80],modelsav[80];  
            pmij(pmmij,cov,ncovmodel,x,nlstate);
   /* long total_usecs;          
   struct timeval start_time, end_time;          k=0;
            for(i=1; i<=(nlstate); i++){
   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */            for(j=1; j<=(nlstate+ndeath);j++){
   getcwd(pathcd, size);              k=k+1;
               mu[k][(int) age]=pmmij[i][j];
   printf("\n%s",version);            }
   if(argc <=1){          }
     printf("\nEnter the parameter file name: ");          for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
     scanf("%s",pathtot);            for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
   }              varpij[i][j][(int)age] = doldm[i][j];
   else{  
     strcpy(pathtot,argv[1]);          /*printf("\n%d ",(int)age);
   }            for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
   /*if(getcwd(pathcd, 80)!= NULL)printf ("Error pathcd\n");*/            printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
   /*cygwin_split_path(pathtot,path,optionfile);            fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/            }*/
   /* cutv(path,optionfile,pathtot,'\\');*/  
           fprintf(ficresprob,"\n%d ",(int)age);
   split(pathtot,path,optionfile,optionfilext,optionfilefiname);          fprintf(ficresprobcov,"\n%d ",(int)age);
    printf("pathtot=%s, path=%s, optionfile=%s optionfilext=%s optionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);          fprintf(ficresprobcor,"\n%d ",(int)age);
   chdir(path);  
   replace(pathc,path);          for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
             fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
 /*-------- arguments in the command line --------*/          for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
             fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
   strcpy(fileres,"r");            fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
   strcat(fileres, optionfilefiname);          }
   strcat(fileres,".txt");    /* Other files have txt extension */          i=0;
           for (k=1; k<=(nlstate);k++){
   /*---------arguments file --------*/            for (l=1; l<=(nlstate+ndeath);l++){ 
               i=i++;
   if((ficpar=fopen(optionfile,"r"))==NULL)    {              fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
     printf("Problem with optionfile %s\n",optionfile);              fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
     goto end;              for (j=1; j<=i;j++){
   }                fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                 fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
   strcpy(filereso,"o");              }
   strcat(filereso,fileres);            }
   if((ficparo=fopen(filereso,"w"))==NULL) {          }/* end of loop for state */
     printf("Problem with Output resultfile: %s\n", filereso);goto end;        } /* end of loop for age */
   }  
         /* Confidence intervalle of pij  */
   /* Reads comments: lines beginning with '#' */        /*
   while((c=getc(ficpar))=='#' && c!= EOF){          fprintf(ficgp,"\nset noparametric;unset label");
     ungetc(c,ficpar);          fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
     fgets(line, MAXLINE, ficpar);          fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
     puts(line);          fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
     fputs(line,ficparo);          fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
   }          fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
   ungetc(c,ficpar);          fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
         */
   fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model);  
   printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model);        /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model);        first1=1;
 while((c=getc(ficpar))=='#' && c!= EOF){        for (k2=1; k2<=(nlstate);k2++){
     ungetc(c,ficpar);          for (l2=1; l2<=(nlstate+ndeath);l2++){ 
     fgets(line, MAXLINE, ficpar);            if(l2==k2) continue;
     puts(line);            j=(k2-1)*(nlstate+ndeath)+l2;
     fputs(line,ficparo);            for (k1=1; k1<=(nlstate);k1++){
   }              for (l1=1; l1<=(nlstate+ndeath);l1++){ 
   ungetc(c,ficpar);                if(l1==k1) continue;
                  i=(k1-1)*(nlstate+ndeath)+l1;
                    if(i<=j) continue;
   covar=matrix(0,NCOVMAX,1,n);                for (age=bage; age<=fage; age ++){ 
   cptcovn=0;                  if ((int)age %5==0){
   if (strlen(model)>1) cptcovn=nbocc(model,'+')+1;                    v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                     v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
   ncovmodel=2+cptcovn;                    cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
   nvar=ncovmodel-1; /* Suppressing age as a basic covariate */                    mu1=mu[i][(int) age]/stepm*YEARM ;
                      mu2=mu[j][(int) age]/stepm*YEARM;
   /* Read guess parameters */                    c12=cv12/sqrt(v1*v2);
   /* Reads comments: lines beginning with '#' */                    /* Computing eigen value of matrix of covariance */
   while((c=getc(ficpar))=='#' && c!= EOF){                    lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
     ungetc(c,ficpar);                    lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
     fgets(line, MAXLINE, ficpar);                    /* Eigen vectors */
     puts(line);                    v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
     fputs(line,ficparo);                    /*v21=sqrt(1.-v11*v11); *//* error */
   }                    v21=(lc1-v1)/cv12*v11;
   ungetc(c,ficpar);                    v12=-v21;
                      v22=v11;
   param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);                    tnalp=v21/v11;
     for(i=1; i <=nlstate; i++)                    if(first1==1){
     for(j=1; j <=nlstate+ndeath-1; j++){                      first1=0;
       fscanf(ficpar,"%1d%1d",&i1,&j1);                      printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
       fprintf(ficparo,"%1d%1d",i1,j1);                    }
       printf("%1d%1d",i,j);                    fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
       for(k=1; k<=ncovmodel;k++){                    /*printf(fignu*/
         fscanf(ficpar," %lf",&param[i][j][k]);                    /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
         printf(" %lf",param[i][j][k]);                    /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
         fprintf(ficparo," %lf",param[i][j][k]);                    if(first==1){
       }                      first=0;
       fscanf(ficpar,"\n");                      fprintf(ficgp,"\nset parametric;unset label");
       printf("\n");                      fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
       fprintf(ficparo,"\n");                      fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
     }                      fprintf(fichtm,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup> :<a href=\"varpijgr%s%d%1d%1d-%1d%1d.png\">varpijgr%s%d%1d%1d-%1d%1d.png</A>, ",k1,l1,k2,l2,optionfilefiname, j1,k1,l1,k2,l2,optionfilefiname, j1,k1,l1,k2,l2);
                        fprintf(fichtm,"\n<br><img src=\"varpijgr%s%d%1d%1d-%1d%1d.png\"> ",optionfilefiname, j1,k1,l1,k2,l2);
     npar= (nlstate+ndeath-1)*nlstate*ncovmodel;                      fprintf(fichtm,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                       fprintf(ficgp,"\nset out \"varpijgr%s%d%1d%1d-%1d%1d.png\"",optionfilefiname, j1,k1,l1,k2,l2);
   p=param[1][1];                      fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                        fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
   /* Reads comments: lines beginning with '#' */                      fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",\
   while((c=getc(ficpar))=='#' && c!= EOF){                              mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),\
     ungetc(c,ficpar);                              mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
     fgets(line, MAXLINE, ficpar);                    }else{
     puts(line);                      first=0;
     fputs(line,ficparo);                      fprintf(fichtm," %d (%.3f),",(int) age, c12);
   }                      fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
   ungetc(c,ficpar);                      fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                       fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",\
   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);                              mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),\
   delti=vector(1,npar); /* Scale of each paramater (output from hesscov) */                              mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
   for(i=1; i <=nlstate; i++){                    }/* if first */
     for(j=1; j <=nlstate+ndeath-1; j++){                  } /* age mod 5 */
       fscanf(ficpar,"%1d%1d",&i1,&j1);                } /* end loop age */
       printf("%1d%1d",i,j);                fprintf(ficgp,"\nset out \"varpijgr%s%d%1d%1d-%1d%1d.png\";replot;",optionfilefiname, j1,k1,l1,k2,l2);
       fprintf(ficparo,"%1d%1d",i1,j1);                first=1;
       for(k=1; k<=ncovmodel;k++){              } /*l12 */
         fscanf(ficpar,"%le",&delti3[i][j][k]);            } /* k12 */
         printf(" %le",delti3[i][j][k]);          } /*l1 */
         fprintf(ficparo," %le",delti3[i][j][k]);        }/* k1 */
       }      } /* loop covariates */
       fscanf(ficpar,"\n");    }
       printf("\n");    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
       fprintf(ficparo,"\n");    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
     }    free_vector(xp,1,npar);
   }    fclose(ficresprob);
   delti=delti3[1][1];    fclose(ficresprobcov);
      fclose(ficresprobcor);
   /* Reads comments: lines beginning with '#' */    fclose(ficgp);
   while((c=getc(ficpar))=='#' && c!= EOF){    fclose(fichtm);
     ungetc(c,ficpar);  }
     fgets(line, MAXLINE, ficpar);  
     puts(line);  
     fputs(line,ficparo);  /******************* Printing html file ***********/
   }  void printinghtml(char fileres[], char title[], char datafile[], int firstpass, \
   ungetc(c,ficpar);                    int lastpass, int stepm, int weightopt, char model[],\
                      int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
   matcov=matrix(1,npar,1,npar);                    int popforecast, int estepm ,\
   for(i=1; i <=npar; i++){                    double jprev1, double mprev1,double anprev1, \
     fscanf(ficpar,"%s",&str);                    double jprev2, double mprev2,double anprev2){
     printf("%s",str);    int jj1, k1, i1, cpt;
     fprintf(ficparo,"%s",str);    /*char optionfilehtm[FILENAMELENGTH];*/
     for(j=1; j <=i; j++){    if((fichtm=fopen(optionfilehtm,"a"))==NULL)    {
       fscanf(ficpar," %le",&matcov[i][j]);      printf("Problem with %s \n",optionfilehtm), exit(0);
       printf(" %.5le",matcov[i][j]);      fprintf(ficlog,"Problem with %s \n",optionfilehtm), exit(0);
       fprintf(ficparo," %.5le",matcov[i][j]);    }
     }  
     fscanf(ficpar,"\n");     fprintf(fichtm,"<ul><li><h4>Result files (first order: no variance)</h4>\n
     printf("\n");   - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"p%s\">p%s</a> <br>\n
     fprintf(ficparo,"\n");   - Estimated transition probabilities over %d (stepm) months: <a href=\"pij%s\">pij%s</a><br>\n
   }   - Stable prevalence in each health state: <a href=\"pl%s\">pl%s</a> <br>\n
   for(i=1; i <=npar; i++)   - Life expectancies by age and initial health status (estepm=%2d months): 
     for(j=i+1;j<=npar;j++)     <a href=\"e%s\">e%s</a> <br>\n</li>", \
       matcov[i][j]=matcov[j][i];    jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,fileres,fileres,stepm,fileres,fileres,fileres,fileres,estepm,fileres,fileres);
      
   printf("\n");  fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
   
    m=cptcoveff;
     /*-------- Rewriting paramater file ----------*/   if (cptcovn < 1) {m=1;ncodemax[1]=1;}
      strcpy(rfileres,"r");    /* "Rparameterfile */  
      strcat(rfileres,optionfilefiname);    /* Parameter file first name*/   jj1=0;
      strcat(rfileres,".");    /* */   for(k1=1; k1<=m;k1++){
      strcat(rfileres,optionfilext);    /* Other files have txt extension */     for(i1=1; i1<=ncodemax[k1];i1++){
     if((ficres =fopen(rfileres,"w"))==NULL) {       jj1++;
       printf("Problem writing new parameter file: %s\n", fileres);goto end;       if (cptcovn > 0) {
     }         fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
     fprintf(ficres,"#%s\n",version);         for (cpt=1; cpt<=cptcoveff;cpt++) 
               fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtab[jj1][cpt]]);
     /*-------- data file ----------*/         fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
     if((fic=fopen(datafile,"r"))==NULL)    {       }
       printf("Problem with datafile: %s\n", datafile);goto end;       /* Pij */
     }       fprintf(fichtm,"<br>- Pij or Conditional probabilities to be observed in state j being in state i, %d (stepm) months before: pe%s%d1.png<br>
   <img src=\"pe%s%d1.png\">",stepm,strtok(optionfile, "."),jj1,strtok(optionfile, "."),jj1);     
     n= lastobs;       /* Quasi-incidences */
     severity = vector(1,maxwav);       fprintf(fichtm,"<br>- Pij or Conditional probabilities to be observed in state j being in state i %d (stepm) months before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too: pe%s%d2.png<br>
     outcome=imatrix(1,maxwav+1,1,n);  <img src=\"pe%s%d2.png\">",stepm,strtok(optionfile, "."),jj1,strtok(optionfile, "."),jj1); 
     num=ivector(1,n);         /* Stable prevalence in each health state */
     moisnais=vector(1,n);         for(cpt=1; cpt<nlstate;cpt++){
     annais=vector(1,n);           fprintf(fichtm,"<br>- Stable prevalence in each health state : p%s%d%d.png<br>
     moisdc=vector(1,n);  <img src=\"p%s%d%d.png\">",strtok(optionfile, "."),cpt,jj1,strtok(optionfile, "."),cpt,jj1);
     andc=vector(1,n);         }
     agedc=vector(1,n);       for(cpt=1; cpt<=nlstate;cpt++) {
     cod=ivector(1,n);          fprintf(fichtm,"\n<br>- Health life expectancies by age and initial health state (%d): exp%s%d%d.png <br>
     weight=vector(1,n);  <img src=\"exp%s%d%d.png\">",cpt,strtok(optionfile, "."),cpt,jj1,strtok(optionfile, "."),cpt,jj1);
     for(i=1;i<=n;i++) weight[i]=1.0; /* Equal weights, 1 by default */       }
     mint=matrix(1,maxwav,1,n);       fprintf(fichtm,"\n<br>- Total life expectancy by age and
     anint=matrix(1,maxwav,1,n);  health expectancies in states (1) and (2): e%s%d.png<br>
     s=imatrix(1,maxwav+1,1,n);  <img src=\"e%s%d.png\">",strtok(optionfile, "."),jj1,strtok(optionfile, "."),jj1);
     adl=imatrix(1,maxwav+1,1,n);         } /* end i1 */
     tab=ivector(1,NCOVMAX);   }/* End k1 */
     ncodemax=ivector(1,8);   fprintf(fichtm,"</ul>");
   
     i=1;  
     while (fgets(line, MAXLINE, fic) != NULL)    {   fprintf(fichtm,"\n<br><li><h4> Result files (second order: variances)</h4>\n
       if ((i >= firstobs) && (i <=lastobs)) {   - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br>\n
           - Variance of one-step probabilities: <a href=\"prob%s\">prob%s</a> <br>\n
         for (j=maxwav;j>=1;j--){   - Variance-covariance of one-step probabilities: <a href=\"probcov%s\">probcov%s</a> <br>\n
           cutv(stra, strb,line,' '); s[j][i]=atoi(strb);   - Correlation matrix of one-step probabilities: <a href=\"probcor%s\">probcor%s</a> <br>\n
           strcpy(line,stra);   - Variances and covariances of life expectancies by age and initial health status (estepm=%d months): <a href=\"v%s\">v%s</a><br>\n 
           cutv(stra, strb,line,'/'); anint[j][i]=(double)(atoi(strb)); strcpy(line,stra);   - Health expectancies with their variances (no covariance): <a href=\"t%s\">t%s</a> <br>\n
           cutv(stra, strb,line,' '); mint[j][i]=(double)(atoi(strb)); strcpy(line,stra);   - Standard deviation of stable prevalences: <a href=\"vpl%s\">vpl%s</a> <br>\n",rfileres,rfileres,fileres,fileres,fileres,fileres,fileres,fileres, estepm, fileres,fileres,fileres,fileres,fileres,fileres);
         }  
          /*  if(popforecast==1) fprintf(fichtm,"\n */
         cutv(stra, strb,line,'/'); andc[i]=(double)(atoi(strb)); strcpy(line,stra);  /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
         cutv(stra, strb,line,' '); moisdc[i]=(double)(atoi(strb)); strcpy(line,stra);  /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
   /*      <br>",fileres,fileres,fileres,fileres); */
         cutv(stra, strb,line,'/'); annais[i]=(double)(atoi(strb)); strcpy(line,stra);  /*  else  */
         cutv(stra, strb,line,' '); moisnais[i]=(double)(atoi(strb)); strcpy(line,stra);  /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
   fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
         cutv(stra, strb,line,' '); weight[i]=(double)(atoi(strb)); strcpy(line,stra);  
         for (j=ncovcol;j>=1;j--){   m=cptcoveff;
           cutv(stra, strb,line,' '); covar[j][i]=(double)(atoi(strb)); strcpy(line,stra);   if (cptcovn < 1) {m=1;ncodemax[1]=1;}
         }  
         num[i]=atol(stra);   jj1=0;
           for(k1=1; k1<=m;k1++){
         /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){     for(i1=1; i1<=ncodemax[k1];i1++){
           printf("%d %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/       jj1++;
        if (cptcovn > 0) {
         i=i+1;         fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
       }         for (cpt=1; cpt<=cptcoveff;cpt++) 
     }           fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtab[jj1][cpt]]);
     /* printf("ii=%d", ij);         fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
        scanf("%d",i);*/       }
   imx=i-1; /* Number of individuals */       for(cpt=1; cpt<=nlstate;cpt++) {
          fprintf(fichtm,"<br>- Observed and period prevalence (with confident
   /* for (i=1; i<=imx; i++){  interval) in state (%d): v%s%d%d.png <br>
     if ((s[1][i]==3) && (s[2][i]==2)) s[2][i]=3;  <img src=\"v%s%d%d.png\">",cpt,strtok(optionfile, "."),cpt,jj1,strtok(optionfile, "."),cpt,jj1);  
     if ((s[2][i]==3) && (s[3][i]==2)) s[3][i]=3;       }
     if ((s[3][i]==3) && (s[4][i]==2)) s[4][i]=3;     } /* end i1 */
     }*/   }/* End k1 */
    /*  for (i=1; i<=imx; i++){   fprintf(fichtm,"</ul>");
      if (s[4][i]==9)  s[4][i]=-1;  fclose(fichtm);
      printf("%d %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]), (weight[i]), (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i]));}*/  }
    
    /******************* Gnuplot file **************/
   /* Calculation of the number of parameter from char model*/  void printinggnuplot(char fileres[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
   Tvar=ivector(1,15);  
   Tprod=ivector(1,15);    int m,cpt,k1,i,k,j,jk,k2,k3,ij,l;
   Tvaraff=ivector(1,15);    int ng;
   Tvard=imatrix(1,15,1,2);    if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) {
   Tage=ivector(1,15);            printf("Problem with file %s",optionfilegnuplot);
          fprintf(ficlog,"Problem with file %s",optionfilegnuplot);
   if (strlen(model) >1){    }
     j=0, j1=0, k1=1, k2=1;  
     j=nbocc(model,'+');    /*#ifdef windows */
     j1=nbocc(model,'*');      fprintf(ficgp,"cd \"%s\" \n",pathc);
     cptcovn=j+1;      /*#endif */
     cptcovprod=j1;  m=pow(2,cptcoveff);
        
     strcpy(modelsav,model);   /* 1eme*/
     if ((strcmp(model,"age")==0) || (strcmp(model,"age*age")==0)){    for (cpt=1; cpt<= nlstate ; cpt ++) {
       printf("Error. Non available option model=%s ",model);     for (k1=1; k1<= m ; k1 ++) {
       goto end;       fprintf(ficgp,"\nset out \"v%s%d%d.png\" \n",strtok(optionfile, "."),cpt,k1);
     }       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter png small\nset size 0.65,0.65\nplot [%.f:%.f] \"vpl%s\" every :::%d::%d u 1:2 \"\%%lf",ageminpar,fage,fileres,k1-1,k1-1);
      
     for(i=(j+1); i>=1;i--){       for (i=1; i<= nlstate ; i ++) {
       cutv(stra,strb,modelsav,'+');         if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");
       if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav);         else fprintf(ficgp," \%%*lf (\%%*lf)");
       /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/       }
       /*scanf("%d",i);*/       fprintf(ficgp,"\" t\"Stable prevalence\" w l 0,\"vpl%s\" every :::%d::%d u 1:($2+1.96*$3) \"\%%lf",fileres,k1-1,k1-1);
       if (strchr(strb,'*')) {       for (i=1; i<= nlstate ; i ++) {
         cutv(strd,strc,strb,'*');         if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");
         if (strcmp(strc,"age")==0) {         else fprintf(ficgp," \%%*lf (\%%*lf)");
           cptcovprod--;       } 
           cutv(strb,stre,strd,'V');       fprintf(ficgp,"\" t\"95\%% CI\" w l 1,\"vpl%s\" every :::%d::%d u 1:($2-1.96*$3) \"\%%lf",fileres,k1-1,k1-1); 
           Tvar[i]=atoi(stre);       for (i=1; i<= nlstate ; i ++) {
           cptcovage++;         if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");
             Tage[cptcovage]=i;         else fprintf(ficgp," \%%*lf (\%%*lf)");
             /*printf("stre=%s ", stre);*/       }  
         }       fprintf(ficgp,"\" t\"\" w l 1,\"p%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence \" w l 2",fileres,k1-1,k1-1,2+4*(cpt-1));
         else if (strcmp(strd,"age")==0) {     }
           cptcovprod--;    }
           cutv(strb,stre,strc,'V');    /*2 eme*/
           Tvar[i]=atoi(stre);    
           cptcovage++;    for (k1=1; k1<= m ; k1 ++) { 
           Tage[cptcovage]=i;      fprintf(ficgp,"\nset out \"e%s%d.png\" \n",strtok(optionfile, "."),k1);
         }      fprintf(ficgp,"set ylabel \"Years\" \nset ter png small\nset size 0.65,0.65\nplot [%.f:%.f] ",ageminpar,fage);
         else {      
           cutv(strb,stre,strc,'V');      for (i=1; i<= nlstate+1 ; i ++) {
           Tvar[i]=ncovcol+k1;        k=2*i;
           cutv(strb,strc,strd,'V');        fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:2 \"\%%lf",fileres,k1-1,k1-1);
           Tprod[k1]=i;        for (j=1; j<= nlstate+1 ; j ++) {
           Tvard[k1][1]=atoi(strc);          if (j==i) fprintf(ficgp," \%%lf (\%%lf)");
           Tvard[k1][2]=atoi(stre);          else fprintf(ficgp," \%%*lf (\%%*lf)");
           Tvar[cptcovn+k2]=Tvard[k1][1];        }   
           Tvar[cptcovn+k2+1]=Tvard[k1][2];        if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l ,");
           for (k=1; k<=lastobs;k++)        else fprintf(ficgp,"\" t\"LE in state (%d)\" w l ,",i-1);
             covar[ncovcol+k1][k]=covar[atoi(stre)][k]*covar[atoi(strc)][k];        fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:($2-$3*2) \"\%%lf",fileres,k1-1,k1-1);
           k1++;        for (j=1; j<= nlstate+1 ; j ++) {
           k2=k2+2;          if (j==i) fprintf(ficgp," \%%lf (\%%lf)");
         }          else fprintf(ficgp," \%%*lf (\%%*lf)");
       }        }   
       else {        fprintf(ficgp,"\" t\"\" w l 0,");
         /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/        fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:($2+$3*2) \"\%%lf",fileres,k1-1,k1-1);
        /*  scanf("%d",i);*/        for (j=1; j<= nlstate+1 ; j ++) {
       cutv(strd,strc,strb,'V');          if (j==i) fprintf(ficgp," \%%lf (\%%lf)");
       Tvar[i]=atoi(strc);          else fprintf(ficgp," \%%*lf (\%%*lf)");
       }        }   
       strcpy(modelsav,stra);          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l 0");
       /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);        else fprintf(ficgp,"\" t\"\" w l 0,");
         scanf("%d",i);*/      }
     }    }
 }    
      /*3eme*/
   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);    
   printf("cptcovprod=%d ", cptcovprod);    for (k1=1; k1<= m ; k1 ++) { 
   scanf("%d ",i);*/      for (cpt=1; cpt<= nlstate ; cpt ++) {
     fclose(fic);        k=2+nlstate*(2*cpt-2);
         fprintf(ficgp,"\nset out \"exp%s%d%d.png\" \n",strtok(optionfile, "."),cpt,k1);
     /*  if(mle==1){*/        fprintf(ficgp,"set ter png small\nset size 0.65,0.65\nplot [%.f:%.f] \"e%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,fileres,k1-1,k1-1,k,cpt);
     if (weightopt != 1) { /* Maximisation without weights*/        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
       for(i=1;i<=n;i++) weight[i]=1.0;          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
     }          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
     /*-calculation of age at interview from date of interview and age at death -*/          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
     agev=matrix(1,maxwav,1,imx);          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
           fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
     for (i=1; i<=imx; i++) {          
       for(m=2; (m<= maxwav); m++) {        */
        if ((mint[m][i]== 99) && (s[m][i] <= nlstate)){        for (i=1; i< nlstate ; i ++) {
          anint[m][i]=9999;          fprintf(ficgp," ,\"e%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",fileres,k1-1,k1-1,k+2*i,cpt,i+1);
          s[m][i]=-1;          
        }        } 
      if(moisdc[i]==99 && andc[i]==9999 & s[m][i]>nlstate) s[m][i]=-1;      }
       }    }
     }    
     /* CV preval stable (period) */
     for (i=1; i<=imx; i++)  {    for (k1=1; k1<= m ; k1 ++) { 
       agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);      for (cpt=1; cpt<=nlstate ; cpt ++) {
       for(m=1; (m<= maxwav); m++){        k=3;
         if(s[m][i] >0){        fprintf(ficgp,"\nset out \"p%s%d%d.png\" \n",strtok(optionfile, "."),cpt,k1);
           if (s[m][i] >= nlstate+1) {        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter png small\nset size 0.65,0.65\nplot [%.f:%.f] \"pij%s\" u ($1==%d ? ($3):1/0):($%d/($%d",ageminpar,agemaxpar,fileres,k1,k+cpt+1,k+1);
             if(agedc[i]>0)        
               if(moisdc[i]!=99 && andc[i]!=9999)        for (i=1; i<= nlstate ; i ++)
                 agev[m][i]=agedc[i];          fprintf(ficgp,"+$%d",k+i+1);
             /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/        fprintf(ficgp,")) t\"prev(%d,%d)\" w l",cpt,cpt+1);
            else {        
               if (andc[i]!=9999){        l=3+(nlstate+ndeath)*cpt;
               printf("Warning negative age at death: %d line:%d\n",num[i],i);        fprintf(ficgp,",\"pij%s\" u ($1==%d ? ($3):1/0):($%d/($%d",fileres,k1,l+cpt+1,l+1);
               agev[m][i]=-1;        for (i=1; i< nlstate ; i ++) {
               }          l=3+(nlstate+ndeath)*cpt;
             }          fprintf(ficgp,"+$%d",l+i+1);
           }        }
           else if(s[m][i] !=9){ /* Should no more exist */        fprintf(ficgp,")) t\"prev(%d,%d)\" w l\n",cpt+1,cpt+1);   
             agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);      } 
             if(mint[m][i]==99 || anint[m][i]==9999)    }  
               agev[m][i]=1;    
             else if(agev[m][i] <agemin){    /* proba elementaires */
               agemin=agev[m][i];    for(i=1,jk=1; i <=nlstate; i++){
               /*printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], agemin);*/      for(k=1; k <=(nlstate+ndeath); k++){
             }        if (k != i) {
             else if(agev[m][i] >agemax){          for(j=1; j <=ncovmodel; j++){
               agemax=agev[m][i];            fprintf(ficgp,"p%d=%f ",jk,p[jk]);
              /* printf(" anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.0f\n",m,i,anint[m][i], i,annais[i], agemax);*/            jk++; 
             }            fprintf(ficgp,"\n");
             /*agev[m][i]=anint[m][i]-annais[i];*/          }
             /*   agev[m][i] = age[i]+2*m;*/        }
           }      }
           else { /* =9 */     }
             agev[m][i]=1;  
             s[m][i]=-1;     for(ng=1; ng<=2;ng++){ /* Number of graphics: first is probabilities second is incidence per year*/
           }       for(jk=1; jk <=m; jk++) {
         }         fprintf(ficgp,"\nset out \"pe%s%d%d.png\" \n",strtok(optionfile, "."),jk,ng); 
         else /*= 0 Unknown */         if (ng==2)
           agev[m][i]=1;           fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
       }         else
               fprintf(ficgp,"\nset title \"Probability\"\n");
     }         fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65\nset log y\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
     for (i=1; i<=imx; i++)  {         i=1;
       for(m=1; (m<= maxwav); m++){         for(k2=1; k2<=nlstate; k2++) {
         if (s[m][i] > (nlstate+ndeath)) {           k3=i;
           printf("Error: Wrong value in nlstate or ndeath\n");             for(k=1; k<=(nlstate+ndeath); k++) {
           goto end;             if (k != k2){
         }               if(ng==2)
       }                 fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
     }               else
                  fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
 printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, agemin, agemax);               ij=1;
                for(j=3; j <=ncovmodel; j++) {
     free_vector(severity,1,maxwav);                 if(((j-2)==Tage[ij]) &&(ij <=cptcovage)) {
     free_imatrix(outcome,1,maxwav+1,1,n);                   fprintf(ficgp,"+p%d*%d*x",i+j-1,nbcode[Tvar[j-2]][codtab[jk][Tvar[j-2]]]);
     free_vector(moisnais,1,n);                   ij++;
     free_vector(annais,1,n);                 }
     /* free_matrix(mint,1,maxwav,1,n);                 else
        free_matrix(anint,1,maxwav,1,n);*/                   fprintf(ficgp,"+p%d*%d",i+j-1,nbcode[Tvar[j-2]][codtab[jk][j-2]]);
     free_vector(moisdc,1,n);               }
     free_vector(andc,1,n);               fprintf(ficgp,")/(1");
                
                   for(k1=1; k1 <=nlstate; k1++){   
     wav=ivector(1,imx);                 fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
     dh=imatrix(1,lastpass-firstpass+1,1,imx);                 ij=1;
     mw=imatrix(1,lastpass-firstpass+1,1,imx);                 for(j=3; j <=ncovmodel; j++){
                       if(((j-2)==Tage[ij]) &&(ij <=cptcovage)) {
     /* Concatenates waves */                     fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2,nbcode[Tvar[j-2]][codtab[jk][Tvar[j-2]]]);
       concatwav(wav, dh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);                     ij++;
                    }
                    else
       Tcode=ivector(1,100);                     fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2,nbcode[Tvar[j-2]][codtab[jk][j-2]]);
       nbcode=imatrix(0,NCOVMAX,0,NCOVMAX);                 }
       ncodemax[1]=1;                 fprintf(ficgp,")");
       if (cptcovn > 0) tricode(Tvar,nbcode,imx);               }
                     fprintf(ficgp,") t \"p%d%d\" ", k2,k);
    codtab=imatrix(1,100,1,10);               if ((k+k2)!= (nlstate*2+ndeath)) fprintf(ficgp,",");
    h=0;               i=i+ncovmodel;
    m=pow(2,cptcoveff);             }
             } /* end k */
    for(k=1;k<=cptcoveff; k++){         } /* end k2 */
      for(i=1; i <=(m/pow(2,k));i++){       } /* end jk */
        for(j=1; j <= ncodemax[k]; j++){     } /* end ng */
          for(cpt=1; cpt <=(m/pow(2,cptcoveff+1-k)); cpt++){     fclose(ficgp); 
            h++;  }  /* end gnuplot */
            if (h>m) h=1;codtab[h][k]=j;codtab[h][Tvar[k]]=j;  
            /*  printf("h=%d k=%d j=%d codtab[h][k]=%d tvar[k]=%d \n",h, k,j,codtab[h][k],Tvar[k]);*/  
          }  /*************** Moving average **************/
        }  int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav){
      }  
    }    int i, cpt, cptcod;
    /* printf("codtab[1][2]=%d codtab[2][2]=%d",codtab[1][2],codtab[2][2]);    int modcovmax =1;
       codtab[1][2]=1;codtab[2][2]=2; */    int mobilavrange, mob;
    /* for(i=1; i <=m ;i++){    double age;
       for(k=1; k <=cptcovn; k++){  
       printf("i=%d k=%d %d %d ",i,k,codtab[i][k], cptcoveff);    modcovmax=2*cptcoveff;/* Max number of modalities. We suppose 
       }                             a covariate has 2 modalities */
       printf("\n");    if (cptcovn<1) modcovmax=1; /* At least 1 pass */
       }  
       scanf("%d",i);*/    if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
          if(mobilav==1) mobilavrange=5; /* default */
    /* Calculates basic frequencies. Computes observed prevalence at single age      else mobilavrange=mobilav;
        and prints on file fileres'p'. */      for (age=bage; age<=fage; age++)
         for (i=1; i<=nlstate;i++)
              for (cptcod=1;cptcod<=modcovmax;cptcod++)
                mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
     pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */      /* We keep the original values on the extreme ages bage, fage and for 
     oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */         fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
     newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */         we use a 5 terms etc. until the borders are no more concerned. 
     savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */      */ 
     oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */      for (mob=3;mob <=mobilavrange;mob=mob+2){
              for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
     /* For Powell, parameters are in a vector p[] starting at p[1]          for (i=1; i<=nlstate;i++){
        so we point p on param[1][1] so that p[1] maps on param[1][1][1] */            for (cptcod=1;cptcod<=modcovmax;cptcod++){
     p=param[1][1]; /* *(*(*(param +1)+1)+0) */              mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                 for (cpt=1;cpt<=(mob-1)/2;cpt++){
     if(mle==1){                  mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
     mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);                  mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
     }                }
                  mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
     /*--------- results files --------------*/            }
     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate, ndeath, maxwav, weightopt,model);          }
          }/* end age */
       }/* end mob */
    jk=1;    }else return -1;
    fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");    return 0;
    printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");  }/* End movingaverage */
    for(i=1,jk=1; i <=nlstate; i++){  
      for(k=1; k <=(nlstate+ndeath); k++){  
        if (k != i)  /************** Forecasting ******************/
          {  prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
            printf("%d%d ",i,k);    /* proj1, year, month, day of starting projection 
            fprintf(ficres,"%1d%1d ",i,k);       agemin, agemax range of age
            for(j=1; j <=ncovmodel; j++){       dateprev1 dateprev2 range of dates during which prevalence is computed
              printf("%f ",p[jk]);       anproj2 year of en of projection (same day and month as proj1).
              fprintf(ficres,"%f ",p[jk]);    */
              jk++;    int yearp, stepsize, hstepm, nhstepm, j, k, c, cptcod, i, h, i1;
            }    int *popage;
            printf("\n");    double agec; /* generic age */
            fprintf(ficres,"\n");    double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
          }    double *popeffectif,*popcount;
      }    double ***p3mat;
    }    double ***mobaverage;
  if(mle==1){    char fileresf[FILENAMELENGTH];
     /* Computing hessian and covariance matrix */  
     ftolhess=ftol; /* Usually correct */    agelim=AGESUP;
     hesscov(matcov, p, npar, delti, ftolhess, func);    prevalence(ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
  }   
     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");    strcpy(fileresf,"f"); 
     printf("# Scales (for hessian or gradient estimation)\n");    strcat(fileresf,fileres);
      for(i=1,jk=1; i <=nlstate; i++){    if((ficresf=fopen(fileresf,"w"))==NULL) {
       for(j=1; j <=nlstate+ndeath; j++){      printf("Problem with forecast resultfile: %s\n", fileresf);
         if (j!=i) {      fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
           fprintf(ficres,"%1d%1d",i,j);    }
           printf("%1d%1d",i,j);    printf("Computing forecasting: result on file '%s' \n", fileresf);
           for(k=1; k<=ncovmodel;k++){    fprintf(ficlog,"Computing forecasting: result on file '%s' \n", fileresf);
             printf(" %.5e",delti[jk]);  
             fprintf(ficres," %.5e",delti[jk]);    if (cptcoveff==0) ncodemax[cptcoveff]=1;
             jk++;  
           }    if (mobilav!=0) {
           printf("\n");      mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
           fprintf(ficres,"\n");      if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){
         }        fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
       }        printf(" Error in movingaverage mobilav=%d\n",mobilav);
      }      }
        }
     k=1;  
     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");    stepsize=(int) (stepm+YEARM-1)/YEARM;
     printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");    if (stepm<=12) stepsize=1;
     for(i=1;i<=npar;i++){    if(estepm < stepm){
       /*  if (k>nlstate) k=1;      printf ("Problem %d lower than %d\n",estepm, stepm);
       i1=(i-1)/(ncovmodel*nlstate)+1;    }
       fprintf(ficres,"%s%d%d",alph[k],i1,tab[i]);    else  hstepm=estepm;   
       printf("%s%d%d",alph[k],i1,tab[i]);*/  
       fprintf(ficres,"%3d",i);    hstepm=hstepm/stepm; 
       printf("%3d",i);    yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
       for(j=1; j<=i;j++){                                 fractional in yp1 */
         fprintf(ficres," %.5e",matcov[i][j]);    anprojmean=yp;
         printf(" %.5e",matcov[i][j]);    yp2=modf((yp1*12),&yp);
       }    mprojmean=yp;
       fprintf(ficres,"\n");    yp1=modf((yp2*30.5),&yp);
       printf("\n");    jprojmean=yp;
       k++;    if(jprojmean==0) jprojmean=1;
     }    if(mprojmean==0) jprojmean=1;
      
     while((c=getc(ficpar))=='#' && c!= EOF){    i1=cptcoveff;
       ungetc(c,ficpar);    if (cptcovn < 1){i1=1;}
       fgets(line, MAXLINE, ficpar);    
       puts(line);    fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
       fputs(line,ficparo);    
     }    fprintf(ficresf,"#****** Routine prevforecast **\n");
     ungetc(c,ficpar);  
     estepm=0;  /*            if (h==(int)(YEARM*yearp)){ */
     fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm);    for(cptcov=1, k=0;cptcov<=i1;cptcov++){
     if (estepm==0 || estepm < stepm) estepm=stepm;      for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){
     if (fage <= 2) {        k=k+1;
       bage = ageminpar;        fprintf(ficresf,"\n#******");
       fage = agemaxpar;        for(j=1;j<=cptcoveff;j++) {
     }          fprintf(ficresf," V%d=%d, hpijx=probability over h years, hp.jx is weighted by observed prev ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
            }
     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");        fprintf(ficresf,"******\n");
     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d\n",ageminpar,agemaxpar,bage,fage, estepm);        fprintf(ficresf,"# Covariate valuofcovar yearproj age");
     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d\n",ageminpar,agemaxpar,bage,fage, estepm);        for(j=1; j<=nlstate+ndeath;j++){ 
            for(i=1; i<=nlstate;i++)              
     while((c=getc(ficpar))=='#' && c!= EOF){            fprintf(ficresf," p%d%d",i,j);
     ungetc(c,ficpar);          fprintf(ficresf," p.%d",j);
     fgets(line, MAXLINE, ficpar);        }
     puts(line);        for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) { 
     fputs(line,ficparo);          fprintf(ficresf,"\n");
   }          fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
   ungetc(c,ficpar);  
            for (agec=fage; agec>=(ageminpar-1); agec--){ 
   fscanf(ficpar,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2);            nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
   fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);            nhstepm = nhstepm/hstepm; 
  fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);            p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                  oldm=oldms;savm=savms;
   while((c=getc(ficpar))=='#' && c!= EOF){            hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k);  
     ungetc(c,ficpar);          
     fgets(line, MAXLINE, ficpar);            for (h=0; h<=nhstepm; h++){
     puts(line);              if (h*hstepm/YEARM*stepm ==yearp) {
     fputs(line,ficparo);                fprintf(ficresf,"\n");
   }                for(j=1;j<=cptcoveff;j++) 
   ungetc(c,ficpar);                  fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
                  fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
               } 
    dateprev1=anprev1+mprev1/12.+jprev1/365.;              for(j=1; j<=nlstate+ndeath;j++) {
    dateprev2=anprev2+mprev2/12.+jprev2/365.;                ppij=0.;
                 for(i=1; i<=nlstate;i++) {
   fscanf(ficpar,"pop_based=%d\n",&popbased);                  if (mobilav==1) 
   fprintf(ficparo,"pop_based=%d\n",popbased);                      ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod];
   fprintf(ficres,"pop_based=%d\n",popbased);                    else {
                      ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod];
   while((c=getc(ficpar))=='#' && c!= EOF){                  }
     ungetc(c,ficpar);                  if (h*hstepm/YEARM*stepm== yearp) {
     fgets(line, MAXLINE, ficpar);                    fprintf(ficresf," %.3f", p3mat[i][j][h]);
     puts(line);                  }
     fputs(line,ficparo);                } /* end i */
   }                if (h*hstepm/YEARM*stepm==yearp) {
   ungetc(c,ficpar);                  fprintf(ficresf," %.3f", ppij);
                 }
   fscanf(ficpar,"starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mov_average=%d\n",&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilav);              }/* end j */
 fprintf(ficparo,"starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mov_average=%d\n",jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilav);            } /* end h */
 fprintf(ficres,"starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mov_average=%d\n",jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilav);            free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           } /* end agec */
         } /* end yearp */
 while((c=getc(ficpar))=='#' && c!= EOF){      } /* end cptcod */
     ungetc(c,ficpar);    } /* end  cptcov */
     fgets(line, MAXLINE, ficpar);         
     puts(line);    if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     fputs(line,ficparo);  
   }    fclose(ficresf);
   ungetc(c,ficpar);  }
   
   fscanf(ficpar,"popforecast=%d popfile=%s popfiledate=%lf/%lf/%lf last-popfiledate=%lf/%lf/%lf\n",&popforecast,popfile,&jpyram,&mpyram,&anpyram,&jpyram1,&mpyram1,&anpyram1);  /************** Forecasting *****not tested NB*************/
   fprintf(ficparo,"popforecast=%d popfile=%s popfiledate=%.lf/%.lf/%.lf last-popfiledate=%.lf/%.lf/%.lf\n",popforecast,popfile,jpyram,mpyram,anpyram,jpyram1,mpyram1,anpyram1);  populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){
   fprintf(ficres,"popforecast=%d popfile=%s popfiledate=%.lf/%.lf/%.lf last-popfiledate=%.lf/%.lf/%.lf\n",popforecast,popfile,jpyram,mpyram,anpyram,jpyram1,mpyram1,anpyram1);    
     int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h;
  freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax,mint,anint,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);    int *popage;
     double calagedatem, agelim, kk1, kk2;
 /*------------ gnuplot -------------*/    double *popeffectif,*popcount;
  printinggnuplot(fileres,optionfilefiname,optionfile,optionfilegnuplot, ageminpar,agemaxpar,fage, pathc,p);    double ***p3mat,***tabpop,***tabpopprev;
      double ***mobaverage;
 /*------------ free_vector  -------------*/    char filerespop[FILENAMELENGTH];
  chdir(path);  
      tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
  free_ivector(wav,1,imx);    tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
  free_imatrix(dh,1,lastpass-firstpass+1,1,imx);    agelim=AGESUP;
  free_imatrix(mw,1,lastpass-firstpass+1,1,imx);      calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM;
  free_ivector(num,1,n);    
  free_vector(agedc,1,n);    prevalence(ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
  /*free_matrix(covar,1,NCOVMAX,1,n);*/    
  fclose(ficparo);    
  fclose(ficres);    strcpy(filerespop,"pop"); 
     strcat(filerespop,fileres);
 /*--------- index.htm --------*/    if((ficrespop=fopen(filerespop,"w"))==NULL) {
       printf("Problem with forecast resultfile: %s\n", filerespop);
   printinghtml(fileres,title,datafile, firstpass, lastpass, stepm, weightopt,model,imx,jmin,jmax,jmean,optionfile,optionfilehtm,rfileres,optionfilegnuplot,version,popforecast,estepm);      fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop);
     }
      printf("Computing forecasting: result on file '%s' \n", filerespop);
   /*--------------- Prevalence limit --------------*/    fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop);
    
   strcpy(filerespl,"pl");    if (cptcoveff==0) ncodemax[cptcoveff]=1;
   strcat(filerespl,fileres);  
   if((ficrespl=fopen(filerespl,"w"))==NULL) {    if (mobilav!=0) {
     printf("Problem with Prev limit resultfile: %s\n", filerespl);goto end;      mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
   }      if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){
   printf("Computing prevalence limit: result on file '%s' \n", filerespl);        fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
   fprintf(ficrespl,"#Prevalence limit\n");        printf(" Error in movingaverage mobilav=%d\n",mobilav);
   fprintf(ficrespl,"#Age ");      }
   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);    }
   fprintf(ficrespl,"\n");  
      stepsize=(int) (stepm+YEARM-1)/YEARM;
   prlim=matrix(1,nlstate,1,nlstate);    if (stepm<=12) stepsize=1;
   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */    
   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */    agelim=AGESUP;
   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */    
   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */    hstepm=1;
   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */    hstepm=hstepm/stepm; 
   k=0;    
   agebase=ageminpar;    if (popforecast==1) {
   agelim=agemaxpar;      if((ficpop=fopen(popfile,"r"))==NULL) {
   ftolpl=1.e-10;        printf("Problem with population file : %s\n",popfile);exit(0);
   i1=cptcoveff;        fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0);
   if (cptcovn < 1){i1=1;}      } 
       popage=ivector(0,AGESUP);
   for(cptcov=1;cptcov<=i1;cptcov++){      popeffectif=vector(0,AGESUP);
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){      popcount=vector(0,AGESUP);
         k=k+1;      
         /*printf("cptcov=%d cptcod=%d codtab=%d nbcode=%d\n",cptcov, cptcod,Tcode[cptcode],codtab[cptcod][cptcov]);*/      i=1;   
         fprintf(ficrespl,"\n#******");      while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1;
         for(j=1;j<=cptcoveff;j++)     
           fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);      imx=i;
         fprintf(ficrespl,"******\n");      for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i];
            }
         for (age=agebase; age<=agelim; age++){  
           prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);    for(cptcov=1,k=0;cptcov<=i2;cptcov++){
           fprintf(ficrespl,"%.0f",age );     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){
           for(i=1; i<=nlstate;i++)        k=k+1;
           fprintf(ficrespl," %.5f", prlim[i][i]);        fprintf(ficrespop,"\n#******");
           fprintf(ficrespl,"\n");        for(j=1;j<=cptcoveff;j++) {
         }          fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
       }        }
     }        fprintf(ficrespop,"******\n");
   fclose(ficrespl);        fprintf(ficrespop,"# Age");
         for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j);
   /*------------- h Pij x at various ages ------------*/        if (popforecast==1)  fprintf(ficrespop," [Population]");
          
   strcpy(filerespij,"pij");  strcat(filerespij,fileres);        for (cpt=0; cpt<=0;cpt++) { 
   if((ficrespij=fopen(filerespij,"w"))==NULL) {          fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);   
     printf("Problem with Pij resultfile: %s\n", filerespij);goto end;          
   }          for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){ 
   printf("Computing pij: result on file '%s' \n", filerespij);            nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); 
              nhstepm = nhstepm/hstepm; 
   stepsize=(int) (stepm+YEARM-1)/YEARM;            
   /*if (stepm<=24) stepsize=2;*/            p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             oldm=oldms;savm=savms;
   agelim=AGESUP;            hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
   hstepm=stepsize*YEARM; /* Every year of age */          
   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */            for (h=0; h<=nhstepm; h++){
                if (h==(int) (calagedatem+YEARM*cpt)) {
   k=0;                fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm);
   for(cptcov=1;cptcov<=i1;cptcov++){              } 
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){              for(j=1; j<=nlstate+ndeath;j++) {
       k=k+1;                kk1=0.;kk2=0;
         fprintf(ficrespij,"\n#****** ");                for(i=1; i<=nlstate;i++) {              
         for(j=1;j<=cptcoveff;j++)                  if (mobilav==1) 
           fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);                    kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod];
         fprintf(ficrespij,"******\n");                  else {
                            kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod];
         for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */                  }
           nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */                }
           nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */                if (h==(int)(calagedatem+12*cpt)){
           p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);                  tabpop[(int)(agedeb)][j][cptcod]=kk1;
           oldm=oldms;savm=savms;                    /*fprintf(ficrespop," %.3f", kk1);
           hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);                        if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*/
           fprintf(ficrespij,"# Age");                }
           for(i=1; i<=nlstate;i++)              }
             for(j=1; j<=nlstate+ndeath;j++)              for(i=1; i<=nlstate;i++){
               fprintf(ficrespij," %1d-%1d",i,j);                kk1=0.;
           fprintf(ficrespij,"\n");                  for(j=1; j<=nlstate;j++){
            for (h=0; h<=nhstepm; h++){                    kk1= kk1+tabpop[(int)(agedeb)][j][cptcod]; 
             fprintf(ficrespij,"%d %.0f %.0f",k,agedeb, agedeb+ h*hstepm/YEARM*stepm );                  }
             for(i=1; i<=nlstate;i++)                    tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)];
               for(j=1; j<=nlstate+ndeath;j++)              }
                 fprintf(ficrespij," %.5f", p3mat[i][j][h]);  
             fprintf(ficrespij,"\n");              if (h==(int)(calagedatem+12*cpt)) for(j=1; j<=nlstate;j++) 
              }                fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]);
           free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);            }
           fprintf(ficrespij,"\n");            free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
         }          }
     }        }
   }   
     /******/
   varprob(fileres, matcov, p, delti, nlstate, (int) bage, (int) fage,k,Tvar,nbcode, ncodemax);  
         for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) { 
   fclose(ficrespij);          fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);   
           for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){ 
             nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); 
   /*---------- Forecasting ------------------*/            nhstepm = nhstepm/hstepm; 
   if((stepm == 1) && (strcmp(model,".")==0)){            
     prevforecast(fileres, anproj1,mproj1,jproj1, agemin,agemax, dateprev1, dateprev2,mobilav, agedeb, fage, popforecast, popfile, anproj2,p, i1);            p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     if (popforecast==1) populforecast(fileres, anpyram,mpyram,jpyram, agemin,agemax, dateprev1, dateprev2,mobilav, agedeb, fage, popforecast, popfile, anpyram1,p, i1);            oldm=oldms;savm=savms;
   }            hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
   else{            for (h=0; h<=nhstepm; h++){
     erreur=108;              if (h==(int) (calagedatem+YEARM*cpt)) {
     printf("Warning %d!! You can only forecast the prevalences if the optimization\n  has been performed with stepm = 1 (month) instead of %d or model=. instead of '%s'\n", erreur, stepm, model);                fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm);
   }              } 
                for(j=1; j<=nlstate+ndeath;j++) {
                 kk1=0.;kk2=0;
   /*---------- Health expectancies and variances ------------*/                for(i=1; i<=nlstate;i++) {              
                   kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];    
   strcpy(filerest,"t");                }
   strcat(filerest,fileres);                if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);        
   if((ficrest=fopen(filerest,"w"))==NULL) {              }
     printf("Problem with total LE resultfile: %s\n", filerest);goto end;            }
   }            free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
   printf("Computing Total LEs with variances: file '%s' \n", filerest);          }
         }
      } 
   strcpy(filerese,"e");    }
   strcat(filerese,fileres);   
   if((ficreseij=fopen(filerese,"w"))==NULL) {    if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);  
   }    if (popforecast==1) {
   printf("Computing Health Expectancies: result on file '%s' \n", filerese);      free_ivector(popage,0,AGESUP);
       free_vector(popeffectif,0,AGESUP);
  strcpy(fileresv,"v");      free_vector(popcount,0,AGESUP);
   strcat(fileresv,fileres);    }
   if((ficresvij=fopen(fileresv,"w"))==NULL) {    free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     printf("Problem with variance resultfile: %s\n", fileresv);exit(0);    free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
   }    fclose(ficrespop);
   printf("Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);  }
   calagedate=-1;  
 prevalence(ageminpar, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax,mint,anint,dateprev1,dateprev2, calagedate);  /***********************************************/
   /**************** Main Program *****************/
   k=0;  /***********************************************/
   for(cptcov=1;cptcov<=i1;cptcov++){  
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){  int main(int argc, char *argv[])
       k=k+1;  {
       fprintf(ficrest,"\n#****** ");    int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
       for(j=1;j<=cptcoveff;j++)    int i,j, k, n=MAXN,iter,m,size=100,cptcode, cptcod;
         fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);    double agedeb, agefin,hf;
       fprintf(ficrest,"******\n");    double ageminpar=1.e20,agemin=1.e20, agemaxpar=-1.e20, agemax=-1.e20;
   
       fprintf(ficreseij,"\n#****** ");    double fret;
       for(j=1;j<=cptcoveff;j++)    double **xi,tmp,delta;
         fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);  
       fprintf(ficreseij,"******\n");    double dum; /* Dummy variable */
     double ***p3mat;
       fprintf(ficresvij,"\n#****** ");    double ***mobaverage;
       for(j=1;j<=cptcoveff;j++)    int *indx;
         fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);    char line[MAXLINE], linepar[MAXLINE];
       fprintf(ficresvij,"******\n");    char path[80],pathc[80],pathcd[80],pathtot[80],model[80];
     int firstobs=1, lastobs=10;
       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);    int sdeb, sfin; /* Status at beginning and end */
       oldm=oldms;savm=savms;    int c,  h , cpt,l;
       evsij(fileres, eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov);      int ju,jl, mi;
      int i1,j1, k1,k2,k3,jk,aa,bb, stepsize, ij;
       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);    int jnais,jdc,jint4,jint1,jint2,jint3,**outcome,*tab; 
       oldm=oldms;savm=savms;    int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
        varevsij(fileres, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k, estepm);    int mobilav=0,popforecast=0;
        int hstepm, nhstepm;
     double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
      double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
       fprintf(ficrest,"#Total LEs with variances: e.. (std) ");  
       for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);    double bage, fage, age, agelim, agebase;
       fprintf(ficrest,"\n");    double ftolpl=FTOL;
     double **prlim;
       epj=vector(1,nlstate+1);    double *severity;
       for(age=bage; age <=fage ;age++){    double ***param; /* Matrix of parameters */
         prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);    double  *p;
         if (popbased==1) {    double **matcov; /* Matrix of covariance */
           for(i=1; i<=nlstate;i++)    double ***delti3; /* Scale */
             prlim[i][i]=probs[(int)age][i][k];    double *delti; /* Scale */
         }    double ***eij, ***vareij;
            double **varpl; /* Variances of prevalence limits by age */
         fprintf(ficrest," %4.0f",age);    double *epj, vepp;
         for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){    double kk1, kk2;
           for(i=1, epj[j]=0.;i <=nlstate;i++) {    double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
             epj[j] += prlim[i][i]*eij[i][j][(int)age];  
             /*  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/    char *alph[]={"a","a","b","c","d","e"}, str[4];
           }  
           epj[nlstate+1] +=epj[j];  
         }    char z[1]="c", occ;
   #include <sys/time.h>
         for(i=1, vepp=0.;i <=nlstate;i++)  #include <time.h>
           for(j=1;j <=nlstate;j++)    char stra[80], strb[80], strc[80], strd[80],stre[80],modelsav[80];
             vepp += vareij[i][j][(int)age];   
         fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));    /* long total_usecs;
         for(j=1;j <=nlstate;j++){       struct timeval start_time, end_time;
           fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));    
         }       gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
         fprintf(ficrest,"\n");    getcwd(pathcd, size);
       }  
     }    printf("\n%s",version);
   }    if(argc <=1){
 free_matrix(mint,1,maxwav,1,n);      printf("\nEnter the parameter file name: ");
     free_matrix(anint,1,maxwav,1,n); free_imatrix(s,1,maxwav+1,1,n);      scanf("%s",pathtot);
     free_vector(weight,1,n);    }
   fclose(ficreseij);    else{
   fclose(ficresvij);      strcpy(pathtot,argv[1]);
   fclose(ficrest);    }
   fclose(ficpar);    /*if(getcwd(pathcd, 80)!= NULL)printf ("Error pathcd\n");*/
   free_vector(epj,1,nlstate+1);    /*cygwin_split_path(pathtot,path,optionfile);
        printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
   /*------- Variance limit prevalence------*/      /* cutv(path,optionfile,pathtot,'\\');*/
   
   strcpy(fileresvpl,"vpl");    split(pathtot,path,optionfile,optionfilext,optionfilefiname);
   strcat(fileresvpl,fileres);    printf("pathtot=%s, path=%s, optionfile=%s optionfilext=%s optionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
   if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {    chdir(path);
     printf("Problem with variance prev lim resultfile: %s\n", fileresvpl);    replace(pathc,path);
     exit(0);  
   }    /*-------- arguments in the command line --------*/
   printf("Computing Variance-covariance of Prevalence limit: file '%s' \n", fileresvpl);  
     /* Log file */
   k=0;    strcat(filelog, optionfilefiname);
   for(cptcov=1;cptcov<=i1;cptcov++){    strcat(filelog,".log");    /* */
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){    if((ficlog=fopen(filelog,"w"))==NULL)    {
       k=k+1;      printf("Problem with logfile %s\n",filelog);
       fprintf(ficresvpl,"\n#****** ");      goto end;
       for(j=1;j<=cptcoveff;j++)    }
         fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);    fprintf(ficlog,"Log filename:%s\n",filelog);
       fprintf(ficresvpl,"******\n");    fprintf(ficlog,"\n%s",version);
          fprintf(ficlog,"\nEnter the parameter file name: ");
       varpl=matrix(1,nlstate,(int) bage, (int) fage);    fprintf(ficlog,"pathtot=%s, path=%s, optionfile=%s optionfilext=%s optionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
       oldm=oldms;savm=savms;    fflush(ficlog);
      varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k);  
     }    /* */
  }    strcpy(fileres,"r");
     strcat(fileres, optionfilefiname);
   fclose(ficresvpl);    strcat(fileres,".txt");    /* Other files have txt extension */
   
   /*---------- End : free ----------------*/    /*---------arguments file --------*/
   free_matrix(varpl,1,nlstate,(int) bage, (int)fage);  
      if((ficpar=fopen(optionfile,"r"))==NULL)    {
   free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);      printf("Problem with optionfile %s\n",optionfile);
   free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);      fprintf(ficlog,"Problem with optionfile %s\n",optionfile);
        goto end;
      }
   free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);  
   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);    strcpy(filereso,"o");
   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);    strcat(filereso,fileres);
   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);    if((ficparo=fopen(filereso,"w"))==NULL) {
        printf("Problem with Output resultfile: %s\n", filereso);
   free_matrix(matcov,1,npar,1,npar);      fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
   free_vector(delti,1,npar);      goto end;
   free_matrix(agev,1,maxwav,1,imx);    }
   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);  
     /* Reads comments: lines beginning with '#' */
   if(erreur >0)    while((c=getc(ficpar))=='#' && c!= EOF){
     printf("End of Imach with error or warning %d\n",erreur);      ungetc(c,ficpar);
   else   printf("End of Imach\n");      fgets(line, MAXLINE, ficpar);
   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */      puts(line);
        fputs(line,ficparo);
   /* printf("Total time was %d Sec. %d uSec.\n", end_time.tv_sec -start_time.tv_sec, end_time.tv_usec -start_time.tv_usec);*/    }
   /*printf("Total time was %d uSec.\n", total_usecs);*/    ungetc(c,ficpar);
   /*------ End -----------*/  
     fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model);
     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model);
  end:    fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model);
   /* chdir(pathcd);*/    while((c=getc(ficpar))=='#' && c!= EOF){
  /*system("wgnuplot graph.plt");*/      ungetc(c,ficpar);
  /*system("../gp37mgw/wgnuplot graph.plt");*/      fgets(line, MAXLINE, ficpar);
  /*system("cd ../gp37mgw");*/      puts(line);
  /* system("..\\gp37mgw\\wgnuplot graph.plt");*/      fputs(line,ficparo);
  strcpy(plotcmd,GNUPLOTPROGRAM);    }
  strcat(plotcmd," ");    ungetc(c,ficpar);
  strcat(plotcmd,optionfilegnuplot);    
  system(plotcmd);     
     covar=matrix(0,NCOVMAX,1,n); 
  /*#ifdef windows*/    cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement*/
   while (z[0] != 'q') {    if (strlen(model)>1) cptcovn=nbocc(model,'+')+1;
     /* chdir(path); */  
     printf("\nType e to edit output files, g to graph again, c to start again, and q for exiting: ");    ncovmodel=2+cptcovn; /*Number of variables = cptcovn + intercept + age */
     scanf("%s",z);    nvar=ncovmodel-1; /* Suppressing age as a basic covariate */
     if (z[0] == 'c') system("./imach");    
     else if (z[0] == 'e') system(optionfilehtm);    /* Read guess parameters */
     else if (z[0] == 'g') system(plotcmd);    /* Reads comments: lines beginning with '#' */
     else if (z[0] == 'q') exit(0);    while((c=getc(ficpar))=='#' && c!= EOF){
   }      ungetc(c,ficpar);
   /*#endif */      fgets(line, MAXLINE, ficpar);
 }      puts(line);
       fputs(line,ficparo);
     }
     ungetc(c,ficpar);
     
     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
     for(i=1; i <=nlstate; i++)
       for(j=1; j <=nlstate+ndeath-1; j++){
         fscanf(ficpar,"%1d%1d",&i1,&j1);
         fprintf(ficparo,"%1d%1d",i1,j1);
         if(mle==1)
           printf("%1d%1d",i,j);
         fprintf(ficlog,"%1d%1d",i,j);
         for(k=1; k<=ncovmodel;k++){
           fscanf(ficpar," %lf",&param[i][j][k]);
           if(mle==1){
             printf(" %lf",param[i][j][k]);
             fprintf(ficlog," %lf",param[i][j][k]);
           }
           else
             fprintf(ficlog," %lf",param[i][j][k]);
           fprintf(ficparo," %lf",param[i][j][k]);
         }
         fscanf(ficpar,"\n");
         if(mle==1)
           printf("\n");
         fprintf(ficlog,"\n");
         fprintf(ficparo,"\n");
       }
     
     npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/
   
     p=param[1][1];
     
     /* Reads comments: lines beginning with '#' */
     while((c=getc(ficpar))=='#' && c!= EOF){
       ungetc(c,ficpar);
       fgets(line, MAXLINE, ficpar);
       puts(line);
       fputs(line,ficparo);
     }
     ungetc(c,ficpar);
   
     delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
     /* delti=vector(1,npar); *//* Scale of each paramater (output from hesscov) */
     for(i=1; i <=nlstate; i++){
       for(j=1; j <=nlstate+ndeath-1; j++){
         fscanf(ficpar,"%1d%1d",&i1,&j1);
         printf("%1d%1d",i,j);
         fprintf(ficparo,"%1d%1d",i1,j1);
         for(k=1; k<=ncovmodel;k++){
           fscanf(ficpar,"%le",&delti3[i][j][k]);
           printf(" %le",delti3[i][j][k]);
           fprintf(ficparo," %le",delti3[i][j][k]);
         }
         fscanf(ficpar,"\n");
         printf("\n");
         fprintf(ficparo,"\n");
       }
     }
     delti=delti3[1][1];
   
   
     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
     
     /* Reads comments: lines beginning with '#' */
     while((c=getc(ficpar))=='#' && c!= EOF){
       ungetc(c,ficpar);
       fgets(line, MAXLINE, ficpar);
       puts(line);
       fputs(line,ficparo);
     }
     ungetc(c,ficpar);
     
     matcov=matrix(1,npar,1,npar);
     for(i=1; i <=npar; i++){
       fscanf(ficpar,"%s",&str);
       if(mle==1)
         printf("%s",str);
       fprintf(ficlog,"%s",str);
       fprintf(ficparo,"%s",str);
       for(j=1; j <=i; j++){
         fscanf(ficpar," %le",&matcov[i][j]);
         if(mle==1){
           printf(" %.5le",matcov[i][j]);
           fprintf(ficlog," %.5le",matcov[i][j]);
         }
         else
           fprintf(ficlog," %.5le",matcov[i][j]);
         fprintf(ficparo," %.5le",matcov[i][j]);
       }
       fscanf(ficpar,"\n");
       if(mle==1)
         printf("\n");
       fprintf(ficlog,"\n");
       fprintf(ficparo,"\n");
     }
     for(i=1; i <=npar; i++)
       for(j=i+1;j<=npar;j++)
         matcov[i][j]=matcov[j][i];
      
     if(mle==1)
       printf("\n");
     fprintf(ficlog,"\n");
   
   
     /*-------- Rewriting paramater file ----------*/
     strcpy(rfileres,"r");    /* "Rparameterfile */
     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
     strcat(rfileres,".");    /* */
     strcat(rfileres,optionfilext);    /* Other files have txt extension */
     if((ficres =fopen(rfileres,"w"))==NULL) {
       printf("Problem writing new parameter file: %s\n", fileres);goto end;
       fprintf(ficlog,"Problem writing new parameter file: %s\n", fileres);goto end;
     }
     fprintf(ficres,"#%s\n",version);
       
     /*-------- data file ----------*/
     if((fic=fopen(datafile,"r"))==NULL)    {
       printf("Problem with datafile: %s\n", datafile);goto end;
       fprintf(ficlog,"Problem with datafile: %s\n", datafile);goto end;
     }
   
     n= lastobs;
     severity = vector(1,maxwav);
     outcome=imatrix(1,maxwav+1,1,n);
     num=ivector(1,n);
     moisnais=vector(1,n);
     annais=vector(1,n);
     moisdc=vector(1,n);
     andc=vector(1,n);
     agedc=vector(1,n);
     cod=ivector(1,n);
     weight=vector(1,n);
     for(i=1;i<=n;i++) weight[i]=1.0; /* Equal weights, 1 by default */
     mint=matrix(1,maxwav,1,n);
     anint=matrix(1,maxwav,1,n);
     s=imatrix(1,maxwav+1,1,n);
     tab=ivector(1,NCOVMAX);
     ncodemax=ivector(1,8);
   
     i=1;
     while (fgets(line, MAXLINE, fic) != NULL)    {
       if ((i >= firstobs) && (i <=lastobs)) {
           
         for (j=maxwav;j>=1;j--){
           cutv(stra, strb,line,' '); s[j][i]=atoi(strb); 
           strcpy(line,stra);
           cutv(stra, strb,line,'/'); anint[j][i]=(double)(atoi(strb)); strcpy(line,stra);
           cutv(stra, strb,line,' '); mint[j][i]=(double)(atoi(strb)); strcpy(line,stra);
         }
           
         cutv(stra, strb,line,'/'); andc[i]=(double)(atoi(strb)); strcpy(line,stra);
         cutv(stra, strb,line,' '); moisdc[i]=(double)(atoi(strb)); strcpy(line,stra);
   
         cutv(stra, strb,line,'/'); annais[i]=(double)(atoi(strb)); strcpy(line,stra);
         cutv(stra, strb,line,' '); moisnais[i]=(double)(atoi(strb)); strcpy(line,stra);
   
         cutv(stra, strb,line,' '); weight[i]=(double)(atoi(strb)); strcpy(line,stra);
         for (j=ncovcol;j>=1;j--){
           cutv(stra, strb,line,' '); covar[j][i]=(double)(atoi(strb)); strcpy(line,stra);
         } 
         num[i]=atol(stra);
           
         /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
           printf("%d %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
   
         i=i+1;
       }
     }
     /* printf("ii=%d", ij);
        scanf("%d",i);*/
     imx=i-1; /* Number of individuals */
   
     /* for (i=1; i<=imx; i++){
       if ((s[1][i]==3) && (s[2][i]==2)) s[2][i]=3;
       if ((s[2][i]==3) && (s[3][i]==2)) s[3][i]=3;
       if ((s[3][i]==3) && (s[4][i]==2)) s[4][i]=3;
       }*/
      /*  for (i=1; i<=imx; i++){
        if (s[4][i]==9)  s[4][i]=-1; 
        printf("%d %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]), (weight[i]), (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i]));}*/
     
    for (i=1; i<=imx; i++)
    
      /*if ((s[3][i]==3) ||  (s[4][i]==3)) weight[i]=0.08;
        else weight[i]=1;*/
   
     /* Calculation of the number of parameter from char model*/
     Tvar=ivector(1,15); /* stores the number n of the covariates in Vm+Vn at 1 and m at 2 */
     Tprod=ivector(1,15); 
     Tvaraff=ivector(1,15); 
     Tvard=imatrix(1,15,1,2);
     Tage=ivector(1,15);      
      
     if (strlen(model) >1){ /* If there is at least 1 covariate */
       j=0, j1=0, k1=1, k2=1;
       j=nbocc(model,'+'); /* j=Number of '+' */
       j1=nbocc(model,'*'); /* j1=Number of '*' */
       cptcovn=j+1; 
       cptcovprod=j1; /*Number of products */
       
       strcpy(modelsav,model); 
       if ((strcmp(model,"age")==0) || (strcmp(model,"age*age")==0)){
         printf("Error. Non available option model=%s ",model);
         fprintf(ficlog,"Error. Non available option model=%s ",model);
         goto end;
       }
       
       /* This loop fills the array Tvar from the string 'model'.*/
   
       for(i=(j+1); i>=1;i--){
         cutv(stra,strb,modelsav,'+'); /* keeps in strb after the last + */ 
         if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
         /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
         /*scanf("%d",i);*/
         if (strchr(strb,'*')) {  /* Model includes a product */
           cutv(strd,strc,strb,'*'); /* strd*strc  Vm*Vn (if not *age)*/
           if (strcmp(strc,"age")==0) { /* Vn*age */
             cptcovprod--;
             cutv(strb,stre,strd,'V');
             Tvar[i]=atoi(stre); /* computes n in Vn and stores in Tvar*/
             cptcovage++;
               Tage[cptcovage]=i;
               /*printf("stre=%s ", stre);*/
           }
           else if (strcmp(strd,"age")==0) { /* or age*Vn */
             cptcovprod--;
             cutv(strb,stre,strc,'V');
             Tvar[i]=atoi(stre);
             cptcovage++;
             Tage[cptcovage]=i;
           }
           else {  /* Age is not in the model */
             cutv(strb,stre,strc,'V'); /* strc= Vn, stre is n*/
             Tvar[i]=ncovcol+k1;
             cutv(strb,strc,strd,'V'); /* strd was Vm, strc is m */
             Tprod[k1]=i;
             Tvard[k1][1]=atoi(strc); /* m*/
             Tvard[k1][2]=atoi(stre); /* n */
             Tvar[cptcovn+k2]=Tvard[k1][1];
             Tvar[cptcovn+k2+1]=Tvard[k1][2]; 
             for (k=1; k<=lastobs;k++) 
               covar[ncovcol+k1][k]=covar[atoi(stre)][k]*covar[atoi(strc)][k];
             k1++;
             k2=k2+2;
           }
         }
         else { /* no more sum */
           /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
          /*  scanf("%d",i);*/
         cutv(strd,strc,strb,'V');
         Tvar[i]=atoi(strc);
         }
         strcpy(modelsav,stra);  
         /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
           scanf("%d",i);*/
       } /* end of loop + */
     } /* end model */
     
     /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
       If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
   
     /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
     printf("cptcovprod=%d ", cptcovprod);
     fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
   
     scanf("%d ",i);
     fclose(fic);*/
   
       /*  if(mle==1){*/
     if (weightopt != 1) { /* Maximisation without weights*/
       for(i=1;i<=n;i++) weight[i]=1.0;
     }
       /*-calculation of age at interview from date of interview and age at death -*/
     agev=matrix(1,maxwav,1,imx);
   
     for (i=1; i<=imx; i++) {
       for(m=2; (m<= maxwav); m++) {
         if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
           anint[m][i]=9999;
           s[m][i]=-1;
         }
         if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
           printf("Error! Date of death (month %2d and year %4d) of individual %d on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results are biased\n",(int)moisdc[i],(int)andc[i],num[i],i);
           fprintf(ficlog,"Error! Date of death (month %2d and year %4d) of individual %d on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results are biased\n",(int)moisdc[i],(int)andc[i],num[i],i);
           s[m][i]=-1;
         }
         if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
           printf("Error! Month of death of individual %d on line %d was unknown %2d, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,(int)moisdc[i]); 
           fprintf(ficlog,"Error! Month of death of individual %d on line %d was unknown %f, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,moisdc[i]); 
           s[m][i]=-1;
         }
       }
     }
   
     for (i=1; i<=imx; i++)  {
       agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
       for(m=firstpass; (m<= lastpass); m++){
         if(s[m][i] >0){
           if (s[m][i] >= nlstate+1) {
             if(agedc[i]>0)
               if((int)moisdc[i]!=99 && (int)andc[i]!=9999)
                 agev[m][i]=agedc[i];
             /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
               else {
                 if ((int)andc[i]!=9999){
                   printf("Warning negative age at death: %d line:%d\n",num[i],i);
                   fprintf(ficlog,"Warning negative age at death: %d line:%d\n",num[i],i);
                   agev[m][i]=-1;
                 }
               }
           }
           else if(s[m][i] !=9){ /* Standard case, age in fractional
                                    years but with the precision of a
                                    month */
             agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
             if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
               agev[m][i]=1;
             else if(agev[m][i] <agemin){ 
               agemin=agev[m][i];
               /*printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], agemin);*/
             }
             else if(agev[m][i] >agemax){
               agemax=agev[m][i];
               /* printf(" anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.0f\n",m,i,anint[m][i], i,annais[i], agemax);*/
             }
             /*agev[m][i]=anint[m][i]-annais[i];*/
             /*     agev[m][i] = age[i]+2*m;*/
           }
           else { /* =9 */
             agev[m][i]=1;
             s[m][i]=-1;
           }
         }
         else /*= 0 Unknown */
           agev[m][i]=1;
       }
       
     }
     for (i=1; i<=imx; i++)  {
       for(m=firstpass; (m<=lastpass); m++){
         if (s[m][i] > (nlstate+ndeath)) {
           printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
           fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
           goto end;
         }
       }
     }
   
     /*for (i=1; i<=imx; i++){
     for (m=firstpass; (m<lastpass); m++){
        printf("%d %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
   }
   
   }*/
   
     printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, agemin, agemax);
     fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, agemin, agemax); 
   
     free_vector(severity,1,maxwav);
     free_imatrix(outcome,1,maxwav+1,1,n);
     free_vector(moisnais,1,n);
     free_vector(annais,1,n);
     /* free_matrix(mint,1,maxwav,1,n);
        free_matrix(anint,1,maxwav,1,n);*/
     free_vector(moisdc,1,n);
     free_vector(andc,1,n);
   
      
     wav=ivector(1,imx);
     dh=imatrix(1,lastpass-firstpass+1,1,imx);
     bh=imatrix(1,lastpass-firstpass+1,1,imx);
     mw=imatrix(1,lastpass-firstpass+1,1,imx);
      
     /* Concatenates waves */
     concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
   
     /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
   
     Tcode=ivector(1,100);
     nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
     ncodemax[1]=1;
     if (cptcovn > 0) tricode(Tvar,nbcode,imx);
         
     codtab=imatrix(1,100,1,10); /* Cross tabulation to get the order of 
                                    the estimations*/
     h=0;
     m=pow(2,cptcoveff);
    
     for(k=1;k<=cptcoveff; k++){
       for(i=1; i <=(m/pow(2,k));i++){
         for(j=1; j <= ncodemax[k]; j++){
           for(cpt=1; cpt <=(m/pow(2,cptcoveff+1-k)); cpt++){
             h++;
             if (h>m) h=1;codtab[h][k]=j;codtab[h][Tvar[k]]=j;
             /*  printf("h=%d k=%d j=%d codtab[h][k]=%d tvar[k]=%d \n",h, k,j,codtab[h][k],Tvar[k]);*/
           } 
         }
       }
     } 
     /* printf("codtab[1][2]=%d codtab[2][2]=%d",codtab[1][2],codtab[2][2]); 
        codtab[1][2]=1;codtab[2][2]=2; */
     /* for(i=1; i <=m ;i++){ 
        for(k=1; k <=cptcovn; k++){
        printf("i=%d k=%d %d %d ",i,k,codtab[i][k], cptcoveff);
        }
        printf("\n");
        }
        scanf("%d",i);*/
       
     /* Calculates basic frequencies. Computes observed prevalence at single age
        and prints on file fileres'p'. */
   
       pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
       
      
     /* For Powell, parameters are in a vector p[] starting at p[1]
        so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
     p=param[1][1]; /* *(*(*(param +1)+1)+0) */
   
     if(mle>=1){ /* Could be 1 or 2 */
       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
     }
       
     /*--------- results files --------------*/
     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate, ndeath, maxwav, weightopt,model);
     
   
     jk=1;
     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
     for(i=1,jk=1; i <=nlstate; i++){
       for(k=1; k <=(nlstate+ndeath); k++){
         if (k != i) 
           {
             printf("%d%d ",i,k);
             fprintf(ficlog,"%d%d ",i,k);
             fprintf(ficres,"%1d%1d ",i,k);
             for(j=1; j <=ncovmodel; j++){
               printf("%f ",p[jk]);
               fprintf(ficlog,"%f ",p[jk]);
               fprintf(ficres,"%f ",p[jk]);
               jk++; 
             }
             printf("\n");
             fprintf(ficlog,"\n");
             fprintf(ficres,"\n");
           }
       }
     }
     if(mle==1){
       /* Computing hessian and covariance matrix */
       ftolhess=ftol; /* Usually correct */
       hesscov(matcov, p, npar, delti, ftolhess, func);
     }
     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
     printf("# Scales (for hessian or gradient estimation)\n");
     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
     for(i=1,jk=1; i <=nlstate; i++){
       for(j=1; j <=nlstate+ndeath; j++){
         if (j!=i) {
           fprintf(ficres,"%1d%1d",i,j);
           printf("%1d%1d",i,j);
           fprintf(ficlog,"%1d%1d",i,j);
           for(k=1; k<=ncovmodel;k++){
             printf(" %.5e",delti[jk]);
             fprintf(ficlog," %.5e",delti[jk]);
             fprintf(ficres," %.5e",delti[jk]);
             jk++;
           }
           printf("\n");
           fprintf(ficlog,"\n");
           fprintf(ficres,"\n");
         }
       }
     }
      
     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
     if(mle==1)
       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
     for(i=1,k=1;i<=npar;i++){
       /*  if (k>nlstate) k=1;
           i1=(i-1)/(ncovmodel*nlstate)+1; 
           fprintf(ficres,"%s%d%d",alph[k],i1,tab[i]);
           printf("%s%d%d",alph[k],i1,tab[i]);
       */
       fprintf(ficres,"%3d",i);
       if(mle==1)
         printf("%3d",i);
       fprintf(ficlog,"%3d",i);
       for(j=1; j<=i;j++){
         fprintf(ficres," %.5e",matcov[i][j]);
         if(mle==1)
           printf(" %.5e",matcov[i][j]);
         fprintf(ficlog," %.5e",matcov[i][j]);
       }
       fprintf(ficres,"\n");
       if(mle==1)
         printf("\n");
       fprintf(ficlog,"\n");
       k++;
     }
      
     while((c=getc(ficpar))=='#' && c!= EOF){
       ungetc(c,ficpar);
       fgets(line, MAXLINE, ficpar);
       puts(line);
       fputs(line,ficparo);
     }
     ungetc(c,ficpar);
   
     estepm=0;
     fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm);
     if (estepm==0 || estepm < stepm) estepm=stepm;
     if (fage <= 2) {
       bage = ageminpar;
       fage = agemaxpar;
     }
      
     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d\n",ageminpar,agemaxpar,bage,fage, estepm);
     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d\n",ageminpar,agemaxpar,bage,fage, estepm);
      
     while((c=getc(ficpar))=='#' && c!= EOF){
       ungetc(c,ficpar);
       fgets(line, MAXLINE, ficpar);
       puts(line);
       fputs(line,ficparo);
     }
     ungetc(c,ficpar);
     
     fscanf(ficpar,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav);
     fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
     fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
     printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
     fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
      
     while((c=getc(ficpar))=='#' && c!= EOF){
       ungetc(c,ficpar);
       fgets(line, MAXLINE, ficpar);
       puts(line);
       fputs(line,ficparo);
     }
     ungetc(c,ficpar);
    
   
     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
   
     fscanf(ficpar,"pop_based=%d\n",&popbased);
     fprintf(ficparo,"pop_based=%d\n",popbased);   
     fprintf(ficres,"pop_based=%d\n",popbased);   
     
     while((c=getc(ficpar))=='#' && c!= EOF){
       ungetc(c,ficpar);
       fgets(line, MAXLINE, ficpar);
       puts(line);
       fputs(line,ficparo);
     }
     ungetc(c,ficpar);
   
     fscanf(ficpar,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj);
     fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
     printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
     fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
     fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
     /* day and month of proj2 are not used but only year anproj2.*/
   
     while((c=getc(ficpar))=='#' && c!= EOF){
       ungetc(c,ficpar);
       fgets(line, MAXLINE, ficpar);
       puts(line);
       fputs(line,ficparo);
     }
     ungetc(c,ficpar);
   
     fscanf(ficpar,"popforecast=%d popfile=%s popfiledate=%lf/%lf/%lf last-popfiledate=%lf/%lf/%lf\n",&popforecast,popfile,&jpyram,&mpyram,&anpyram,&jpyram1,&mpyram1,&anpyram1);
     fprintf(ficparo,"popforecast=%d popfile=%s popfiledate=%.lf/%.lf/%.lf last-popfiledate=%.lf/%.lf/%.lf\n",popforecast,popfile,jpyram,mpyram,anpyram,jpyram1,mpyram1,anpyram1);
     fprintf(ficres,"popforecast=%d popfile=%s popfiledate=%.lf/%.lf/%.lf last-popfiledate=%.lf/%.lf/%.lf\n",popforecast,popfile,jpyram,mpyram,anpyram,jpyram1,mpyram1,anpyram1);
   
     probs= ma3x(1,AGESUP,1,NCOVMAX, 1,NCOVMAX);
     freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);
   
     /*------------ gnuplot -------------*/
     strcpy(optionfilegnuplot,optionfilefiname);
     strcat(optionfilegnuplot,".gp");
     if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
       printf("Problem with file %s",optionfilegnuplot);
     }
     else{
       fprintf(ficgp,"\n# %s\n", version); 
       fprintf(ficgp,"# %s\n", optionfilegnuplot); 
       fprintf(ficgp,"set missing 'NaNq'\n");
     }
     fclose(ficgp);
     printinggnuplot(fileres, ageminpar,agemaxpar,fage, pathc,p);
     /*--------- index.htm --------*/
   
     strcpy(optionfilehtm,optionfile);
     strcat(optionfilehtm,".htm");
     if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
       printf("Problem with %s \n",optionfilehtm), exit(0);
     }
   
     fprintf(fichtm,"<body> <font size=\"2\">%s </font> <hr size=\"2\" color=\"#EC5E5E\"> \n
   Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=%s<br>\n
   \n
   Total number of observations=%d <br>\n
   Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n
   Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n
   <hr  size=\"2\" color=\"#EC5E5E\">
    <ul><li><h4>Parameter files</h4>\n
    - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n
    - Log file of the run: <a href=\"%s\">%s</a><br>\n
    - Gnuplot file name: <a href=\"%s\">%s</a></ul>\n",version,title,datafile,firstpass,lastpass,stepm, weightopt,model,imx,agemin,agemax,jmin,jmax,jmean,fileres,fileres,filelog,filelog,optionfilegnuplot,optionfilegnuplot);
      fclose(fichtm);
   
     printinghtml(fileres,title,datafile, firstpass, lastpass, stepm, weightopt,model,imx,jmin,jmax,jmean,rfileres,popforecast,estepm,jprev1,mprev1,anprev1,jprev2,mprev2,anprev2);
    
     /*------------ free_vector  -------------*/
     chdir(path);
    
     free_ivector(wav,1,imx);
     free_imatrix(dh,1,lastpass-firstpass+1,1,imx);
     free_imatrix(bh,1,lastpass-firstpass+1,1,imx);
     free_imatrix(mw,1,lastpass-firstpass+1,1,imx);   
     free_ivector(num,1,n);
     free_vector(agedc,1,n);
     /*free_matrix(covar,0,NCOVMAX,1,n);*/
     /*free_matrix(covar,1,NCOVMAX,1,n);*/
     fclose(ficparo);
     fclose(ficres);
   
   
     /*--------------- Prevalence limit  (stable prevalence) --------------*/
     
     strcpy(filerespl,"pl");
     strcat(filerespl,fileres);
     if((ficrespl=fopen(filerespl,"w"))==NULL) {
       printf("Problem with stable prevalence resultfile: %s\n", filerespl);goto end;
       fprintf(ficlog,"Problem with stable prevalence resultfile: %s\n", filerespl);goto end;
     }
     printf("Computing stable prevalence: result on file '%s' \n", filerespl);
     fprintf(ficlog,"Computing stable prevalence: result on file '%s' \n", filerespl);
     fprintf(ficrespl,"#Stable prevalence \n");
     fprintf(ficrespl,"#Age ");
     for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
     fprintf(ficrespl,"\n");
     
     prlim=matrix(1,nlstate,1,nlstate);
   
     agebase=ageminpar;
     agelim=agemaxpar;
     ftolpl=1.e-10;
     i1=cptcoveff;
     if (cptcovn < 1){i1=1;}
   
     for(cptcov=1,k=0;cptcov<=i1;cptcov++){
       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
         k=k+1;
         /*printf("cptcov=%d cptcod=%d codtab=%d nbcode=%d\n",cptcov, cptcod,Tcode[cptcode],codtab[cptcod][cptcov]);*/
         fprintf(ficrespl,"\n#******");
         printf("\n#******");
         fprintf(ficlog,"\n#******");
         for(j=1;j<=cptcoveff;j++) {
           fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
           printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
           fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
         }
         fprintf(ficrespl,"******\n");
         printf("******\n");
         fprintf(ficlog,"******\n");
           
         for (age=agebase; age<=agelim; age++){
           prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);
           fprintf(ficrespl,"%.0f ",age );
           for(j=1;j<=cptcoveff;j++)
             fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
           for(i=1; i<=nlstate;i++)
             fprintf(ficrespl," %.5f", prlim[i][i]);
           fprintf(ficrespl,"\n");
         }
       }
     }
     fclose(ficrespl);
   
     /*------------- h Pij x at various ages ------------*/
     
     strcpy(filerespij,"pij");  strcat(filerespij,fileres);
     if((ficrespij=fopen(filerespij,"w"))==NULL) {
       printf("Problem with Pij resultfile: %s\n", filerespij);goto end;
       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij);goto end;
     }
     printf("Computing pij: result on file '%s' \n", filerespij);
     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
     
     stepsize=(int) (stepm+YEARM-1)/YEARM;
     /*if (stepm<=24) stepsize=2;*/
   
     agelim=AGESUP;
     hstepm=stepsize*YEARM; /* Every year of age */
     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
   
     /* hstepm=1;   aff par mois*/
   
     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
     for(cptcov=1,k=0;cptcov<=i1;cptcov++){
       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
         k=k+1;
         fprintf(ficrespij,"\n#****** ");
         for(j=1;j<=cptcoveff;j++) 
           fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
         fprintf(ficrespij,"******\n");
           
         for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
           nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
           nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
   
           /*        nhstepm=nhstepm*YEARM; aff par mois*/
   
           p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           oldm=oldms;savm=savms;
           hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
           fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
           for(i=1; i<=nlstate;i++)
             for(j=1; j<=nlstate+ndeath;j++)
               fprintf(ficrespij," %1d-%1d",i,j);
           fprintf(ficrespij,"\n");
           for (h=0; h<=nhstepm; h++){
             fprintf(ficrespij,"%d %3.f %3.f",k,agedeb, agedeb+ h*hstepm/YEARM*stepm );
             for(i=1; i<=nlstate;i++)
               for(j=1; j<=nlstate+ndeath;j++)
                 fprintf(ficrespij," %.5f", p3mat[i][j][h]);
             fprintf(ficrespij,"\n");
           }
           free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           fprintf(ficrespij,"\n");
         }
       }
     }
   
     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax);
   
     fclose(ficrespij);
   
   
     /*---------- Forecasting ------------------*/
     /*if((stepm == 1) && (strcmp(model,".")==0)){*/
     if(prevfcast==1){
       /*    if(stepm ==1){*/
         prevforecast(fileres, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
         /* (popforecast==1) populforecast(fileres, anpyram,mpyram,jpyram, agemin,agemax, dateprev1, dateprev2,mobilav, agedeb, fage, popforecast, popfile, anpyram1,p, i1);*/
   /*      }  */
   /*      else{ */
   /*        erreur=108; */
   /*        printf("Warning %d!! You can only forecast the prevalences if the optimization\n  has been performed with stepm = 1 (month) instead of %d or model=. instead of '%s'\n", erreur, stepm, model); */
   /*        fprintf(ficlog,"Warning %d!! You can only forecast the prevalences if the optimization\n  has been performed with stepm = 1 (month) instead of %d or model=. instead of '%s'\n", erreur, stepm, model); */
   /*      } */
     }
     
   
     /*---------- Health expectancies and variances ------------*/
   
     strcpy(filerest,"t");
     strcat(filerest,fileres);
     if((ficrest=fopen(filerest,"w"))==NULL) {
       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
     }
     printf("Computing Total LEs with variances: file '%s' \n", filerest); 
     fprintf(ficlog,"Computing Total LEs with variances: file '%s' \n", filerest); 
   
   
     strcpy(filerese,"e");
     strcat(filerese,fileres);
     if((ficreseij=fopen(filerese,"w"))==NULL) {
       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
     }
     printf("Computing Health Expectancies: result on file '%s' \n", filerese);
     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' \n", filerese);
   
     strcpy(fileresv,"v");
     strcat(fileresv,fileres);
     if((ficresvij=fopen(fileresv,"w"))==NULL) {
       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
     }
     printf("Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);
     fprintf(ficlog,"Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);
   
     /* Computes prevalence between agemin (i.e minimal age computed) and no more ageminpar */
     prevalence(agemin, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
     /*  printf("ageminpar=%f, agemax=%f, s[lastpass][imx]=%d, agev[lastpass][imx]=%f, nlstate=%d, imx=%d,  mint[lastpass][imx]=%f, anint[lastpass][imx]=%f,dateprev1=%f, dateprev2=%f, firstpass=%d, lastpass=%d\n",\
   ageminpar, agemax, s[lastpass][imx], agev[lastpass][imx], nlstate, imx, mint[lastpass][imx],anint[lastpass][imx], dateprev1, dateprev2, firstpass, lastpass);
     */
   
     if (mobilav!=0) {
       mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){
         fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
         printf(" Error in movingaverage mobilav=%d\n",mobilav);
       }
     }
   
     for(cptcov=1,k=0;cptcov<=i1;cptcov++){
       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
         k=k+1; 
         fprintf(ficrest,"\n#****** ");
         for(j=1;j<=cptcoveff;j++) 
           fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
         fprintf(ficrest,"******\n");
   
         fprintf(ficreseij,"\n#****** ");
         for(j=1;j<=cptcoveff;j++) 
           fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
         fprintf(ficreseij,"******\n");
   
         fprintf(ficresvij,"\n#****** ");
         for(j=1;j<=cptcoveff;j++) 
           fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
         fprintf(ficresvij,"******\n");
   
         eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
         oldm=oldms;savm=savms;
         evsij(fileres, eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov);  
    
         vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
         oldm=oldms;savm=savms;
         varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k, estepm, cptcov,cptcod,0, mobilav);
         if(popbased==1){
           varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k, estepm, cptcov,cptcod,popbased,mobilav);
         }
   
    
         fprintf(ficrest,"#Total LEs with variances: e.. (std) ");
         for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
         fprintf(ficrest,"\n");
   
         epj=vector(1,nlstate+1);
         for(age=bage; age <=fage ;age++){
           prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);
           if (popbased==1) {
             if(mobilav ==0){
               for(i=1; i<=nlstate;i++)
                 prlim[i][i]=probs[(int)age][i][k];
             }else{ /* mobilav */ 
               for(i=1; i<=nlstate;i++)
                 prlim[i][i]=mobaverage[(int)age][i][k];
             }
           }
           
           fprintf(ficrest," %4.0f",age);
           for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
             for(i=1, epj[j]=0.;i <=nlstate;i++) {
               epj[j] += prlim[i][i]*eij[i][j][(int)age];
               /*  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
             }
             epj[nlstate+1] +=epj[j];
           }
   
           for(i=1, vepp=0.;i <=nlstate;i++)
             for(j=1;j <=nlstate;j++)
               vepp += vareij[i][j][(int)age];
           fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
           for(j=1;j <=nlstate;j++){
             fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
           }
           fprintf(ficrest,"\n");
         }
         free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
         free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
         free_vector(epj,1,nlstate+1);
       }
     }
     free_vector(weight,1,n);
     free_imatrix(Tvard,1,15,1,2);
     free_imatrix(s,1,maxwav+1,1,n);
     free_matrix(anint,1,maxwav,1,n); 
     free_matrix(mint,1,maxwav,1,n);
     free_ivector(cod,1,n);
     free_ivector(tab,1,NCOVMAX);
     fclose(ficreseij);
     fclose(ficresvij);
     fclose(ficrest);
     fclose(ficpar);
     
     /*------- Variance of stable prevalence------*/   
   
     strcpy(fileresvpl,"vpl");
     strcat(fileresvpl,fileres);
     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
       printf("Problem with variance of stable prevalence  resultfile: %s\n", fileresvpl);
       exit(0);
     }
     printf("Computing Variance-covariance of stable prevalence: file '%s' \n", fileresvpl);
   
     for(cptcov=1,k=0;cptcov<=i1;cptcov++){
       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
         k=k+1;
         fprintf(ficresvpl,"\n#****** ");
         for(j=1;j<=cptcoveff;j++) 
           fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);
         fprintf(ficresvpl,"******\n");
         
         varpl=matrix(1,nlstate,(int) bage, (int) fage);
         oldm=oldms;savm=savms;
         varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k);
         free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
       }
     }
   
     fclose(ficresvpl);
   
     /*---------- End : free ----------------*/
     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
     free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
     free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
     free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
     
     free_matrix(covar,0,NCOVMAX,1,n);
     free_matrix(matcov,1,npar,1,npar);
     /*free_vector(delti,1,npar);*/
     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
     free_matrix(agev,1,maxwav,1,imx);
     free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
     if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     free_ma3x(probs,1,AGESUP,1,NCOVMAX, 1,NCOVMAX);
   
     free_ivector(ncodemax,1,8);
     free_ivector(Tvar,1,15);
     free_ivector(Tprod,1,15);
     free_ivector(Tvaraff,1,15);
     free_ivector(Tage,1,15);
     free_ivector(Tcode,1,100);
   
     /*  fclose(fichtm);*/
     /*  fclose(ficgp);*/ /* ALready done */
     
   
     if(erreur >0){
       printf("End of Imach with error or warning %d\n",erreur);
       fprintf(ficlog,"End of Imach with error or warning %d\n",erreur);
     }else{
      printf("End of Imach\n");
      fprintf(ficlog,"End of Imach\n");
     }
     printf("See log file on %s\n",filelog);
     fclose(ficlog);
     /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
     
     /* printf("Total time was %d Sec. %d uSec.\n", end_time.tv_sec -start_time.tv_sec, end_time.tv_usec -start_time.tv_usec);*/
     /*printf("Total time was %d uSec.\n", total_usecs);*/
     /*------ End -----------*/
   
     end:
   #ifdef windows
     /* chdir(pathcd);*/
   #endif 
    /*system("wgnuplot graph.plt");*/
    /*system("../gp37mgw/wgnuplot graph.plt");*/
    /*system("cd ../gp37mgw");*/
    /* system("..\\gp37mgw\\wgnuplot graph.plt");*/
     strcpy(plotcmd,GNUPLOTPROGRAM);
     strcat(plotcmd," ");
     strcat(plotcmd,optionfilegnuplot);
     printf("Starting graphs with: %s",plotcmd);fflush(stdout);
     system(plotcmd);
     printf(" Wait...");
   
    /*#ifdef windows*/
     while (z[0] != 'q') {
       /* chdir(path); */
       printf("\nType e to edit output files, g to graph again, c to start again, and q for exiting: ");
       scanf("%s",z);
       if (z[0] == 'c') system("./imach");
       else if (z[0] == 'e') system(optionfilehtm);
       else if (z[0] == 'g') system(plotcmd);
       else if (z[0] == 'q') exit(0);
     }
     /*#endif */
   }
   
   

Removed from v.1.41.2.1  
changed lines
  Added in v.1.78


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