Annotation of imach/src/imach.c, revision 1.231

1.231   ! brouard     1: /* $Id: imach.c,v 1.230 2016/08/22 06:55:53 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.231   ! brouard     4:   Revision 1.230  2016/08/22 06:55:53  brouard
        !             5:   Summary: Not working
        !             6: 
1.230     brouard     7:   Revision 1.229  2016/07/23 09:45:53  brouard
                      8:   Summary: Completing for func too
                      9: 
1.229     brouard    10:   Revision 1.228  2016/07/22 17:45:30  brouard
                     11:   Summary: Fixing some arrays, still debugging
                     12: 
1.227     brouard    13:   Revision 1.226  2016/07/12 18:42:34  brouard
                     14:   Summary: temp
                     15: 
1.226     brouard    16:   Revision 1.225  2016/07/12 08:40:03  brouard
                     17:   Summary: saving but not running
                     18: 
1.225     brouard    19:   Revision 1.224  2016/07/01 13:16:01  brouard
                     20:   Summary: Fixes
                     21: 
1.224     brouard    22:   Revision 1.223  2016/02/19 09:23:35  brouard
                     23:   Summary: temporary
                     24: 
1.223     brouard    25:   Revision 1.222  2016/02/17 08:14:50  brouard
                     26:   Summary: Probably last 0.98 stable version 0.98r6
                     27: 
1.222     brouard    28:   Revision 1.221  2016/02/15 23:35:36  brouard
                     29:   Summary: minor bug
                     30: 
1.220     brouard    31:   Revision 1.219  2016/02/15 00:48:12  brouard
                     32:   *** empty log message ***
                     33: 
1.219     brouard    34:   Revision 1.218  2016/02/12 11:29:23  brouard
                     35:   Summary: 0.99 Back projections
                     36: 
1.218     brouard    37:   Revision 1.217  2015/12/23 17:18:31  brouard
                     38:   Summary: Experimental backcast
                     39: 
1.217     brouard    40:   Revision 1.216  2015/12/18 17:32:11  brouard
                     41:   Summary: 0.98r4 Warning and status=-2
                     42: 
                     43:   Version 0.98r4 is now:
                     44:    - displaying an error when status is -1, date of interview unknown and date of death known;
                     45:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                     46:   Older changes concerning s=-2, dating from 2005 have been supersed.
                     47: 
1.216     brouard    48:   Revision 1.215  2015/12/16 08:52:24  brouard
                     49:   Summary: 0.98r4 working
                     50: 
1.215     brouard    51:   Revision 1.214  2015/12/16 06:57:54  brouard
                     52:   Summary: temporary not working
                     53: 
1.214     brouard    54:   Revision 1.213  2015/12/11 18:22:17  brouard
                     55:   Summary: 0.98r4
                     56: 
1.213     brouard    57:   Revision 1.212  2015/11/21 12:47:24  brouard
                     58:   Summary: minor typo
                     59: 
1.212     brouard    60:   Revision 1.211  2015/11/21 12:41:11  brouard
                     61:   Summary: 0.98r3 with some graph of projected cross-sectional
                     62: 
                     63:   Author: Nicolas Brouard
                     64: 
1.211     brouard    65:   Revision 1.210  2015/11/18 17:41:20  brouard
                     66:   Summary: Start working on projected prevalences
                     67: 
1.210     brouard    68:   Revision 1.209  2015/11/17 22:12:03  brouard
                     69:   Summary: Adding ftolpl parameter
                     70:   Author: N Brouard
                     71: 
                     72:   We had difficulties to get smoothed confidence intervals. It was due
                     73:   to the period prevalence which wasn't computed accurately. The inner
                     74:   parameter ftolpl is now an outer parameter of the .imach parameter
                     75:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                     76:   computation are long.
                     77: 
1.209     brouard    78:   Revision 1.208  2015/11/17 14:31:57  brouard
                     79:   Summary: temporary
                     80: 
1.208     brouard    81:   Revision 1.207  2015/10/27 17:36:57  brouard
                     82:   *** empty log message ***
                     83: 
1.207     brouard    84:   Revision 1.206  2015/10/24 07:14:11  brouard
                     85:   *** empty log message ***
                     86: 
1.206     brouard    87:   Revision 1.205  2015/10/23 15:50:53  brouard
                     88:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                     89: 
1.205     brouard    90:   Revision 1.204  2015/10/01 16:20:26  brouard
                     91:   Summary: Some new graphs of contribution to likelihood
                     92: 
1.204     brouard    93:   Revision 1.203  2015/09/30 17:45:14  brouard
                     94:   Summary: looking at better estimation of the hessian
                     95: 
                     96:   Also a better criteria for convergence to the period prevalence And
                     97:   therefore adding the number of years needed to converge. (The
                     98:   prevalence in any alive state shold sum to one
                     99: 
1.203     brouard   100:   Revision 1.202  2015/09/22 19:45:16  brouard
                    101:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    102: 
1.202     brouard   103:   Revision 1.201  2015/09/15 17:34:58  brouard
                    104:   Summary: 0.98r0
                    105: 
                    106:   - Some new graphs like suvival functions
                    107:   - Some bugs fixed like model=1+age+V2.
                    108: 
1.201     brouard   109:   Revision 1.200  2015/09/09 16:53:55  brouard
                    110:   Summary: Big bug thanks to Flavia
                    111: 
                    112:   Even model=1+age+V2. did not work anymore
                    113: 
1.200     brouard   114:   Revision 1.199  2015/09/07 14:09:23  brouard
                    115:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    116: 
1.199     brouard   117:   Revision 1.198  2015/09/03 07:14:39  brouard
                    118:   Summary: 0.98q5 Flavia
                    119: 
1.198     brouard   120:   Revision 1.197  2015/09/01 18:24:39  brouard
                    121:   *** empty log message ***
                    122: 
1.197     brouard   123:   Revision 1.196  2015/08/18 23:17:52  brouard
                    124:   Summary: 0.98q5
                    125: 
1.196     brouard   126:   Revision 1.195  2015/08/18 16:28:39  brouard
                    127:   Summary: Adding a hack for testing purpose
                    128: 
                    129:   After reading the title, ftol and model lines, if the comment line has
                    130:   a q, starting with #q, the answer at the end of the run is quit. It
                    131:   permits to run test files in batch with ctest. The former workaround was
                    132:   $ echo q | imach foo.imach
                    133: 
1.195     brouard   134:   Revision 1.194  2015/08/18 13:32:00  brouard
                    135:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    136: 
1.194     brouard   137:   Revision 1.193  2015/08/04 07:17:42  brouard
                    138:   Summary: 0.98q4
                    139: 
1.193     brouard   140:   Revision 1.192  2015/07/16 16:49:02  brouard
                    141:   Summary: Fixing some outputs
                    142: 
1.192     brouard   143:   Revision 1.191  2015/07/14 10:00:33  brouard
                    144:   Summary: Some fixes
                    145: 
1.191     brouard   146:   Revision 1.190  2015/05/05 08:51:13  brouard
                    147:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    148: 
                    149:   Fix 1+age+.
                    150: 
1.190     brouard   151:   Revision 1.189  2015/04/30 14:45:16  brouard
                    152:   Summary: 0.98q2
                    153: 
1.189     brouard   154:   Revision 1.188  2015/04/30 08:27:53  brouard
                    155:   *** empty log message ***
                    156: 
1.188     brouard   157:   Revision 1.187  2015/04/29 09:11:15  brouard
                    158:   *** empty log message ***
                    159: 
1.187     brouard   160:   Revision 1.186  2015/04/23 12:01:52  brouard
                    161:   Summary: V1*age is working now, version 0.98q1
                    162: 
                    163:   Some codes had been disabled in order to simplify and Vn*age was
                    164:   working in the optimization phase, ie, giving correct MLE parameters,
                    165:   but, as usual, outputs were not correct and program core dumped.
                    166: 
1.186     brouard   167:   Revision 1.185  2015/03/11 13:26:42  brouard
                    168:   Summary: Inclusion of compile and links command line for Intel Compiler
                    169: 
1.185     brouard   170:   Revision 1.184  2015/03/11 11:52:39  brouard
                    171:   Summary: Back from Windows 8. Intel Compiler
                    172: 
1.184     brouard   173:   Revision 1.183  2015/03/10 20:34:32  brouard
                    174:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    175: 
                    176:   We use directest instead of original Powell test; probably no
                    177:   incidence on the results, but better justifications;
                    178:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    179:   wrong results.
                    180: 
1.183     brouard   181:   Revision 1.182  2015/02/12 08:19:57  brouard
                    182:   Summary: Trying to keep directest which seems simpler and more general
                    183:   Author: Nicolas Brouard
                    184: 
1.182     brouard   185:   Revision 1.181  2015/02/11 23:22:24  brouard
                    186:   Summary: Comments on Powell added
                    187: 
                    188:   Author:
                    189: 
1.181     brouard   190:   Revision 1.180  2015/02/11 17:33:45  brouard
                    191:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    192: 
1.180     brouard   193:   Revision 1.179  2015/01/04 09:57:06  brouard
                    194:   Summary: back to OS/X
                    195: 
1.179     brouard   196:   Revision 1.178  2015/01/04 09:35:48  brouard
                    197:   *** empty log message ***
                    198: 
1.178     brouard   199:   Revision 1.177  2015/01/03 18:40:56  brouard
                    200:   Summary: Still testing ilc32 on OSX
                    201: 
1.177     brouard   202:   Revision 1.176  2015/01/03 16:45:04  brouard
                    203:   *** empty log message ***
                    204: 
1.176     brouard   205:   Revision 1.175  2015/01/03 16:33:42  brouard
                    206:   *** empty log message ***
                    207: 
1.175     brouard   208:   Revision 1.174  2015/01/03 16:15:49  brouard
                    209:   Summary: Still in cross-compilation
                    210: 
1.174     brouard   211:   Revision 1.173  2015/01/03 12:06:26  brouard
                    212:   Summary: trying to detect cross-compilation
                    213: 
1.173     brouard   214:   Revision 1.172  2014/12/27 12:07:47  brouard
                    215:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    216: 
1.172     brouard   217:   Revision 1.171  2014/12/23 13:26:59  brouard
                    218:   Summary: Back from Visual C
                    219: 
                    220:   Still problem with utsname.h on Windows
                    221: 
1.171     brouard   222:   Revision 1.170  2014/12/23 11:17:12  brouard
                    223:   Summary: Cleaning some \%% back to %%
                    224: 
                    225:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    226: 
1.170     brouard   227:   Revision 1.169  2014/12/22 23:08:31  brouard
                    228:   Summary: 0.98p
                    229: 
                    230:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    231: 
1.169     brouard   232:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   233:   Summary: update
1.169     brouard   234: 
1.168     brouard   235:   Revision 1.167  2014/12/22 13:50:56  brouard
                    236:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    237: 
                    238:   Testing on Linux 64
                    239: 
1.167     brouard   240:   Revision 1.166  2014/12/22 11:40:47  brouard
                    241:   *** empty log message ***
                    242: 
1.166     brouard   243:   Revision 1.165  2014/12/16 11:20:36  brouard
                    244:   Summary: After compiling on Visual C
                    245: 
                    246:   * imach.c (Module): Merging 1.61 to 1.162
                    247: 
1.165     brouard   248:   Revision 1.164  2014/12/16 10:52:11  brouard
                    249:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    250: 
                    251:   * imach.c (Module): Merging 1.61 to 1.162
                    252: 
1.164     brouard   253:   Revision 1.163  2014/12/16 10:30:11  brouard
                    254:   * imach.c (Module): Merging 1.61 to 1.162
                    255: 
1.163     brouard   256:   Revision 1.162  2014/09/25 11:43:39  brouard
                    257:   Summary: temporary backup 0.99!
                    258: 
1.162     brouard   259:   Revision 1.1  2014/09/16 11:06:58  brouard
                    260:   Summary: With some code (wrong) for nlopt
                    261: 
                    262:   Author:
                    263: 
                    264:   Revision 1.161  2014/09/15 20:41:41  brouard
                    265:   Summary: Problem with macro SQR on Intel compiler
                    266: 
1.161     brouard   267:   Revision 1.160  2014/09/02 09:24:05  brouard
                    268:   *** empty log message ***
                    269: 
1.160     brouard   270:   Revision 1.159  2014/09/01 10:34:10  brouard
                    271:   Summary: WIN32
                    272:   Author: Brouard
                    273: 
1.159     brouard   274:   Revision 1.158  2014/08/27 17:11:51  brouard
                    275:   *** empty log message ***
                    276: 
1.158     brouard   277:   Revision 1.157  2014/08/27 16:26:55  brouard
                    278:   Summary: Preparing windows Visual studio version
                    279:   Author: Brouard
                    280: 
                    281:   In order to compile on Visual studio, time.h is now correct and time_t
                    282:   and tm struct should be used. difftime should be used but sometimes I
                    283:   just make the differences in raw time format (time(&now).
                    284:   Trying to suppress #ifdef LINUX
                    285:   Add xdg-open for __linux in order to open default browser.
                    286: 
1.157     brouard   287:   Revision 1.156  2014/08/25 20:10:10  brouard
                    288:   *** empty log message ***
                    289: 
1.156     brouard   290:   Revision 1.155  2014/08/25 18:32:34  brouard
                    291:   Summary: New compile, minor changes
                    292:   Author: Brouard
                    293: 
1.155     brouard   294:   Revision 1.154  2014/06/20 17:32:08  brouard
                    295:   Summary: Outputs now all graphs of convergence to period prevalence
                    296: 
1.154     brouard   297:   Revision 1.153  2014/06/20 16:45:46  brouard
                    298:   Summary: If 3 live state, convergence to period prevalence on same graph
                    299:   Author: Brouard
                    300: 
1.153     brouard   301:   Revision 1.152  2014/06/18 17:54:09  brouard
                    302:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    303: 
1.152     brouard   304:   Revision 1.151  2014/06/18 16:43:30  brouard
                    305:   *** empty log message ***
                    306: 
1.151     brouard   307:   Revision 1.150  2014/06/18 16:42:35  brouard
                    308:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    309:   Author: brouard
                    310: 
1.150     brouard   311:   Revision 1.149  2014/06/18 15:51:14  brouard
                    312:   Summary: Some fixes in parameter files errors
                    313:   Author: Nicolas Brouard
                    314: 
1.149     brouard   315:   Revision 1.148  2014/06/17 17:38:48  brouard
                    316:   Summary: Nothing new
                    317:   Author: Brouard
                    318: 
                    319:   Just a new packaging for OS/X version 0.98nS
                    320: 
1.148     brouard   321:   Revision 1.147  2014/06/16 10:33:11  brouard
                    322:   *** empty log message ***
                    323: 
1.147     brouard   324:   Revision 1.146  2014/06/16 10:20:28  brouard
                    325:   Summary: Merge
                    326:   Author: Brouard
                    327: 
                    328:   Merge, before building revised version.
                    329: 
1.146     brouard   330:   Revision 1.145  2014/06/10 21:23:15  brouard
                    331:   Summary: Debugging with valgrind
                    332:   Author: Nicolas Brouard
                    333: 
                    334:   Lot of changes in order to output the results with some covariates
                    335:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    336:   improve the code.
                    337:   No more memory valgrind error but a lot has to be done in order to
                    338:   continue the work of splitting the code into subroutines.
                    339:   Also, decodemodel has been improved. Tricode is still not
                    340:   optimal. nbcode should be improved. Documentation has been added in
                    341:   the source code.
                    342: 
1.144     brouard   343:   Revision 1.143  2014/01/26 09:45:38  brouard
                    344:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    345: 
                    346:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    347:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    348: 
1.143     brouard   349:   Revision 1.142  2014/01/26 03:57:36  brouard
                    350:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    351: 
                    352:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    353: 
1.142     brouard   354:   Revision 1.141  2014/01/26 02:42:01  brouard
                    355:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    356: 
1.141     brouard   357:   Revision 1.140  2011/09/02 10:37:54  brouard
                    358:   Summary: times.h is ok with mingw32 now.
                    359: 
1.140     brouard   360:   Revision 1.139  2010/06/14 07:50:17  brouard
                    361:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    362:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    363: 
1.139     brouard   364:   Revision 1.138  2010/04/30 18:19:40  brouard
                    365:   *** empty log message ***
                    366: 
1.138     brouard   367:   Revision 1.137  2010/04/29 18:11:38  brouard
                    368:   (Module): Checking covariates for more complex models
                    369:   than V1+V2. A lot of change to be done. Unstable.
                    370: 
1.137     brouard   371:   Revision 1.136  2010/04/26 20:30:53  brouard
                    372:   (Module): merging some libgsl code. Fixing computation
                    373:   of likelione (using inter/intrapolation if mle = 0) in order to
                    374:   get same likelihood as if mle=1.
                    375:   Some cleaning of code and comments added.
                    376: 
1.136     brouard   377:   Revision 1.135  2009/10/29 15:33:14  brouard
                    378:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    379: 
1.135     brouard   380:   Revision 1.134  2009/10/29 13:18:53  brouard
                    381:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    382: 
1.134     brouard   383:   Revision 1.133  2009/07/06 10:21:25  brouard
                    384:   just nforces
                    385: 
1.133     brouard   386:   Revision 1.132  2009/07/06 08:22:05  brouard
                    387:   Many tings
                    388: 
1.132     brouard   389:   Revision 1.131  2009/06/20 16:22:47  brouard
                    390:   Some dimensions resccaled
                    391: 
1.131     brouard   392:   Revision 1.130  2009/05/26 06:44:34  brouard
                    393:   (Module): Max Covariate is now set to 20 instead of 8. A
                    394:   lot of cleaning with variables initialized to 0. Trying to make
                    395:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    396: 
1.130     brouard   397:   Revision 1.129  2007/08/31 13:49:27  lievre
                    398:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    399: 
1.129     lievre    400:   Revision 1.128  2006/06/30 13:02:05  brouard
                    401:   (Module): Clarifications on computing e.j
                    402: 
1.128     brouard   403:   Revision 1.127  2006/04/28 18:11:50  brouard
                    404:   (Module): Yes the sum of survivors was wrong since
                    405:   imach-114 because nhstepm was no more computed in the age
                    406:   loop. Now we define nhstepma in the age loop.
                    407:   (Module): In order to speed up (in case of numerous covariates) we
                    408:   compute health expectancies (without variances) in a first step
                    409:   and then all the health expectancies with variances or standard
                    410:   deviation (needs data from the Hessian matrices) which slows the
                    411:   computation.
                    412:   In the future we should be able to stop the program is only health
                    413:   expectancies and graph are needed without standard deviations.
                    414: 
1.127     brouard   415:   Revision 1.126  2006/04/28 17:23:28  brouard
                    416:   (Module): Yes the sum of survivors was wrong since
                    417:   imach-114 because nhstepm was no more computed in the age
                    418:   loop. Now we define nhstepma in the age loop.
                    419:   Version 0.98h
                    420: 
1.126     brouard   421:   Revision 1.125  2006/04/04 15:20:31  lievre
                    422:   Errors in calculation of health expectancies. Age was not initialized.
                    423:   Forecasting file added.
                    424: 
                    425:   Revision 1.124  2006/03/22 17:13:53  lievre
                    426:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    427:   The log-likelihood is printed in the log file
                    428: 
                    429:   Revision 1.123  2006/03/20 10:52:43  brouard
                    430:   * imach.c (Module): <title> changed, corresponds to .htm file
                    431:   name. <head> headers where missing.
                    432: 
                    433:   * imach.c (Module): Weights can have a decimal point as for
                    434:   English (a comma might work with a correct LC_NUMERIC environment,
                    435:   otherwise the weight is truncated).
                    436:   Modification of warning when the covariates values are not 0 or
                    437:   1.
                    438:   Version 0.98g
                    439: 
                    440:   Revision 1.122  2006/03/20 09:45:41  brouard
                    441:   (Module): Weights can have a decimal point as for
                    442:   English (a comma might work with a correct LC_NUMERIC environment,
                    443:   otherwise the weight is truncated).
                    444:   Modification of warning when the covariates values are not 0 or
                    445:   1.
                    446:   Version 0.98g
                    447: 
                    448:   Revision 1.121  2006/03/16 17:45:01  lievre
                    449:   * imach.c (Module): Comments concerning covariates added
                    450: 
                    451:   * imach.c (Module): refinements in the computation of lli if
                    452:   status=-2 in order to have more reliable computation if stepm is
                    453:   not 1 month. Version 0.98f
                    454: 
                    455:   Revision 1.120  2006/03/16 15:10:38  lievre
                    456:   (Module): refinements in the computation of lli if
                    457:   status=-2 in order to have more reliable computation if stepm is
                    458:   not 1 month. Version 0.98f
                    459: 
                    460:   Revision 1.119  2006/03/15 17:42:26  brouard
                    461:   (Module): Bug if status = -2, the loglikelihood was
                    462:   computed as likelihood omitting the logarithm. Version O.98e
                    463: 
                    464:   Revision 1.118  2006/03/14 18:20:07  brouard
                    465:   (Module): varevsij Comments added explaining the second
                    466:   table of variances if popbased=1 .
                    467:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    468:   (Module): Function pstamp added
                    469:   (Module): Version 0.98d
                    470: 
                    471:   Revision 1.117  2006/03/14 17:16:22  brouard
                    472:   (Module): varevsij Comments added explaining the second
                    473:   table of variances if popbased=1 .
                    474:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    475:   (Module): Function pstamp added
                    476:   (Module): Version 0.98d
                    477: 
                    478:   Revision 1.116  2006/03/06 10:29:27  brouard
                    479:   (Module): Variance-covariance wrong links and
                    480:   varian-covariance of ej. is needed (Saito).
                    481: 
                    482:   Revision 1.115  2006/02/27 12:17:45  brouard
                    483:   (Module): One freematrix added in mlikeli! 0.98c
                    484: 
                    485:   Revision 1.114  2006/02/26 12:57:58  brouard
                    486:   (Module): Some improvements in processing parameter
                    487:   filename with strsep.
                    488: 
                    489:   Revision 1.113  2006/02/24 14:20:24  brouard
                    490:   (Module): Memory leaks checks with valgrind and:
                    491:   datafile was not closed, some imatrix were not freed and on matrix
                    492:   allocation too.
                    493: 
                    494:   Revision 1.112  2006/01/30 09:55:26  brouard
                    495:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    496: 
                    497:   Revision 1.111  2006/01/25 20:38:18  brouard
                    498:   (Module): Lots of cleaning and bugs added (Gompertz)
                    499:   (Module): Comments can be added in data file. Missing date values
                    500:   can be a simple dot '.'.
                    501: 
                    502:   Revision 1.110  2006/01/25 00:51:50  brouard
                    503:   (Module): Lots of cleaning and bugs added (Gompertz)
                    504: 
                    505:   Revision 1.109  2006/01/24 19:37:15  brouard
                    506:   (Module): Comments (lines starting with a #) are allowed in data.
                    507: 
                    508:   Revision 1.108  2006/01/19 18:05:42  lievre
                    509:   Gnuplot problem appeared...
                    510:   To be fixed
                    511: 
                    512:   Revision 1.107  2006/01/19 16:20:37  brouard
                    513:   Test existence of gnuplot in imach path
                    514: 
                    515:   Revision 1.106  2006/01/19 13:24:36  brouard
                    516:   Some cleaning and links added in html output
                    517: 
                    518:   Revision 1.105  2006/01/05 20:23:19  lievre
                    519:   *** empty log message ***
                    520: 
                    521:   Revision 1.104  2005/09/30 16:11:43  lievre
                    522:   (Module): sump fixed, loop imx fixed, and simplifications.
                    523:   (Module): If the status is missing at the last wave but we know
                    524:   that the person is alive, then we can code his/her status as -2
                    525:   (instead of missing=-1 in earlier versions) and his/her
                    526:   contributions to the likelihood is 1 - Prob of dying from last
                    527:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    528:   the healthy state at last known wave). Version is 0.98
                    529: 
                    530:   Revision 1.103  2005/09/30 15:54:49  lievre
                    531:   (Module): sump fixed, loop imx fixed, and simplifications.
                    532: 
                    533:   Revision 1.102  2004/09/15 17:31:30  brouard
                    534:   Add the possibility to read data file including tab characters.
                    535: 
                    536:   Revision 1.101  2004/09/15 10:38:38  brouard
                    537:   Fix on curr_time
                    538: 
                    539:   Revision 1.100  2004/07/12 18:29:06  brouard
                    540:   Add version for Mac OS X. Just define UNIX in Makefile
                    541: 
                    542:   Revision 1.99  2004/06/05 08:57:40  brouard
                    543:   *** empty log message ***
                    544: 
                    545:   Revision 1.98  2004/05/16 15:05:56  brouard
                    546:   New version 0.97 . First attempt to estimate force of mortality
                    547:   directly from the data i.e. without the need of knowing the health
                    548:   state at each age, but using a Gompertz model: log u =a + b*age .
                    549:   This is the basic analysis of mortality and should be done before any
                    550:   other analysis, in order to test if the mortality estimated from the
                    551:   cross-longitudinal survey is different from the mortality estimated
                    552:   from other sources like vital statistic data.
                    553: 
                    554:   The same imach parameter file can be used but the option for mle should be -3.
                    555: 
1.133     brouard   556:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   557:   former routines in order to include the new code within the former code.
                    558: 
                    559:   The output is very simple: only an estimate of the intercept and of
                    560:   the slope with 95% confident intervals.
                    561: 
                    562:   Current limitations:
                    563:   A) Even if you enter covariates, i.e. with the
                    564:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    565:   B) There is no computation of Life Expectancy nor Life Table.
                    566: 
                    567:   Revision 1.97  2004/02/20 13:25:42  lievre
                    568:   Version 0.96d. Population forecasting command line is (temporarily)
                    569:   suppressed.
                    570: 
                    571:   Revision 1.96  2003/07/15 15:38:55  brouard
                    572:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    573:   rewritten within the same printf. Workaround: many printfs.
                    574: 
                    575:   Revision 1.95  2003/07/08 07:54:34  brouard
                    576:   * imach.c (Repository):
                    577:   (Repository): Using imachwizard code to output a more meaningful covariance
                    578:   matrix (cov(a12,c31) instead of numbers.
                    579: 
                    580:   Revision 1.94  2003/06/27 13:00:02  brouard
                    581:   Just cleaning
                    582: 
                    583:   Revision 1.93  2003/06/25 16:33:55  brouard
                    584:   (Module): On windows (cygwin) function asctime_r doesn't
                    585:   exist so I changed back to asctime which exists.
                    586:   (Module): Version 0.96b
                    587: 
                    588:   Revision 1.92  2003/06/25 16:30:45  brouard
                    589:   (Module): On windows (cygwin) function asctime_r doesn't
                    590:   exist so I changed back to asctime which exists.
                    591: 
                    592:   Revision 1.91  2003/06/25 15:30:29  brouard
                    593:   * imach.c (Repository): Duplicated warning errors corrected.
                    594:   (Repository): Elapsed time after each iteration is now output. It
                    595:   helps to forecast when convergence will be reached. Elapsed time
                    596:   is stamped in powell.  We created a new html file for the graphs
                    597:   concerning matrix of covariance. It has extension -cov.htm.
                    598: 
                    599:   Revision 1.90  2003/06/24 12:34:15  brouard
                    600:   (Module): Some bugs corrected for windows. Also, when
                    601:   mle=-1 a template is output in file "or"mypar.txt with the design
                    602:   of the covariance matrix to be input.
                    603: 
                    604:   Revision 1.89  2003/06/24 12:30:52  brouard
                    605:   (Module): Some bugs corrected for windows. Also, when
                    606:   mle=-1 a template is output in file "or"mypar.txt with the design
                    607:   of the covariance matrix to be input.
                    608: 
                    609:   Revision 1.88  2003/06/23 17:54:56  brouard
                    610:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    611: 
                    612:   Revision 1.87  2003/06/18 12:26:01  brouard
                    613:   Version 0.96
                    614: 
                    615:   Revision 1.86  2003/06/17 20:04:08  brouard
                    616:   (Module): Change position of html and gnuplot routines and added
                    617:   routine fileappend.
                    618: 
                    619:   Revision 1.85  2003/06/17 13:12:43  brouard
                    620:   * imach.c (Repository): Check when date of death was earlier that
                    621:   current date of interview. It may happen when the death was just
                    622:   prior to the death. In this case, dh was negative and likelihood
                    623:   was wrong (infinity). We still send an "Error" but patch by
                    624:   assuming that the date of death was just one stepm after the
                    625:   interview.
                    626:   (Repository): Because some people have very long ID (first column)
                    627:   we changed int to long in num[] and we added a new lvector for
                    628:   memory allocation. But we also truncated to 8 characters (left
                    629:   truncation)
                    630:   (Repository): No more line truncation errors.
                    631: 
                    632:   Revision 1.84  2003/06/13 21:44:43  brouard
                    633:   * imach.c (Repository): Replace "freqsummary" at a correct
                    634:   place. It differs from routine "prevalence" which may be called
                    635:   many times. Probs is memory consuming and must be used with
                    636:   parcimony.
                    637:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    638: 
                    639:   Revision 1.83  2003/06/10 13:39:11  lievre
                    640:   *** empty log message ***
                    641: 
                    642:   Revision 1.82  2003/06/05 15:57:20  brouard
                    643:   Add log in  imach.c and  fullversion number is now printed.
                    644: 
                    645: */
                    646: /*
                    647:    Interpolated Markov Chain
                    648: 
                    649:   Short summary of the programme:
                    650:   
1.227     brouard   651:   This program computes Healthy Life Expectancies or State-specific
                    652:   (if states aren't health statuses) Expectancies from
                    653:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    654: 
                    655:   -1- a first survey ("cross") where individuals from different ages
                    656:   are interviewed on their health status or degree of disability (in
                    657:   the case of a health survey which is our main interest)
                    658: 
                    659:   -2- at least a second wave of interviews ("longitudinal") which
                    660:   measure each change (if any) in individual health status.  Health
                    661:   expectancies are computed from the time spent in each health state
                    662:   according to a model. More health states you consider, more time is
                    663:   necessary to reach the Maximum Likelihood of the parameters involved
                    664:   in the model.  The simplest model is the multinomial logistic model
                    665:   where pij is the probability to be observed in state j at the second
                    666:   wave conditional to be observed in state i at the first
                    667:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    668:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    669:   have a more complex model than "constant and age", you should modify
                    670:   the program where the markup *Covariates have to be included here
                    671:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   672:   convergence.
                    673: 
                    674:   The advantage of this computer programme, compared to a simple
                    675:   multinomial logistic model, is clear when the delay between waves is not
                    676:   identical for each individual. Also, if a individual missed an
                    677:   intermediate interview, the information is lost, but taken into
                    678:   account using an interpolation or extrapolation.  
                    679: 
                    680:   hPijx is the probability to be observed in state i at age x+h
                    681:   conditional to the observed state i at age x. The delay 'h' can be
                    682:   split into an exact number (nh*stepm) of unobserved intermediate
                    683:   states. This elementary transition (by month, quarter,
                    684:   semester or year) is modelled as a multinomial logistic.  The hPx
                    685:   matrix is simply the matrix product of nh*stepm elementary matrices
                    686:   and the contribution of each individual to the likelihood is simply
                    687:   hPijx.
                    688: 
                    689:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   690:   of the life expectancies. It also computes the period (stable) prevalence.
                    691: 
                    692: Back prevalence and projections:
1.227     brouard   693: 
                    694:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    695:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    696:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    697:    mobilavproj)
                    698: 
                    699:     Computes the back prevalence limit for any combination of
                    700:     covariate values k at any age between ageminpar and agemaxpar and
                    701:     returns it in **bprlim. In the loops,
                    702: 
                    703:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    704:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    705: 
                    706:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   707:    Computes for any combination of covariates k and any age between bage and fage 
                    708:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    709:                        oldm=oldms;savm=savms;
1.227     brouard   710: 
                    711:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);
1.218     brouard   712:      Computes the transition matrix starting at age 'age' over
                    713:      'nhstepm*hstepm*stepm' months (i.e. until
                    714:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   715:      nhstepm*hstepm matrices. 
                    716: 
                    717:      Returns p3mat[i][j][h] after calling
                    718:      p3mat[i][j][h]=matprod2(newm,
                    719:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    720:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    721:      oldm);
1.226     brouard   722: 
                    723: Important routines
                    724: 
                    725: - func (or funcone), computes logit (pij) distinguishing
                    726:   o fixed variables (single or product dummies or quantitative);
                    727:   o varying variables by:
                    728:    (1) wave (single, product dummies, quantitative), 
                    729:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    730:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    731:        % varying dummy (not done) or quantitative (not done);
                    732: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    733:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    734: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    735:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    736:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   737: 
1.226     brouard   738: 
                    739:   
1.133     brouard   740:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    741:            Institut national d'études démographiques, Paris.
1.126     brouard   742:   This software have been partly granted by Euro-REVES, a concerted action
                    743:   from the European Union.
                    744:   It is copyrighted identically to a GNU software product, ie programme and
                    745:   software can be distributed freely for non commercial use. Latest version
                    746:   can be accessed at http://euroreves.ined.fr/imach .
                    747: 
                    748:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    749:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    750:   
                    751:   **********************************************************************/
                    752: /*
                    753:   main
                    754:   read parameterfile
                    755:   read datafile
                    756:   concatwav
                    757:   freqsummary
                    758:   if (mle >= 1)
                    759:     mlikeli
                    760:   print results files
                    761:   if mle==1 
                    762:      computes hessian
                    763:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    764:       begin-prev-date,...
                    765:   open gnuplot file
                    766:   open html file
1.145     brouard   767:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    768:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    769:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    770:     freexexit2 possible for memory heap.
                    771: 
                    772:   h Pij x                         | pij_nom  ficrestpij
                    773:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    774:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    775:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    776: 
                    777:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    778:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    779:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    780:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    781:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    782: 
1.126     brouard   783:   forecasting if prevfcast==1 prevforecast call prevalence()
                    784:   health expectancies
                    785:   Variance-covariance of DFLE
                    786:   prevalence()
                    787:    movingaverage()
                    788:   varevsij() 
                    789:   if popbased==1 varevsij(,popbased)
                    790:   total life expectancies
                    791:   Variance of period (stable) prevalence
                    792:  end
                    793: */
                    794: 
1.187     brouard   795: /* #define DEBUG */
                    796: /* #define DEBUGBRENT */
1.203     brouard   797: /* #define DEBUGLINMIN */
                    798: /* #define DEBUGHESS */
                    799: #define DEBUGHESSIJ
1.224     brouard   800: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   801: #define POWELL /* Instead of NLOPT */
1.224     brouard   802: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   803: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    804: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   805: 
                    806: #include <math.h>
                    807: #include <stdio.h>
                    808: #include <stdlib.h>
                    809: #include <string.h>
1.226     brouard   810: #include <ctype.h>
1.159     brouard   811: 
                    812: #ifdef _WIN32
                    813: #include <io.h>
1.172     brouard   814: #include <windows.h>
                    815: #include <tchar.h>
1.159     brouard   816: #else
1.126     brouard   817: #include <unistd.h>
1.159     brouard   818: #endif
1.126     brouard   819: 
                    820: #include <limits.h>
                    821: #include <sys/types.h>
1.171     brouard   822: 
                    823: #if defined(__GNUC__)
                    824: #include <sys/utsname.h> /* Doesn't work on Windows */
                    825: #endif
                    826: 
1.126     brouard   827: #include <sys/stat.h>
                    828: #include <errno.h>
1.159     brouard   829: /* extern int errno; */
1.126     brouard   830: 
1.157     brouard   831: /* #ifdef LINUX */
                    832: /* #include <time.h> */
                    833: /* #include "timeval.h" */
                    834: /* #else */
                    835: /* #include <sys/time.h> */
                    836: /* #endif */
                    837: 
1.126     brouard   838: #include <time.h>
                    839: 
1.136     brouard   840: #ifdef GSL
                    841: #include <gsl/gsl_errno.h>
                    842: #include <gsl/gsl_multimin.h>
                    843: #endif
                    844: 
1.167     brouard   845: 
1.162     brouard   846: #ifdef NLOPT
                    847: #include <nlopt.h>
                    848: typedef struct {
                    849:   double (* function)(double [] );
                    850: } myfunc_data ;
                    851: #endif
                    852: 
1.126     brouard   853: /* #include <libintl.h> */
                    854: /* #define _(String) gettext (String) */
                    855: 
1.141     brouard   856: #define MAXLINE 1024 /* Was 256. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   857: 
                    858: #define GNUPLOTPROGRAM "gnuplot"
                    859: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    860: #define FILENAMELENGTH 132
                    861: 
                    862: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    863: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    864: 
1.144     brouard   865: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    866: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   867: 
                    868: #define NINTERVMAX 8
1.144     brouard   869: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    870: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    871: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   872: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   873: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    874: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   875: #define MAXN 20000
1.144     brouard   876: #define YEARM 12. /**< Number of months per year */
1.218     brouard   877: /* #define AGESUP 130 */
                    878: #define AGESUP 150
                    879: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard   880: #define AGEBASE 40
1.194     brouard   881: #define AGEOVERFLOW 1.e20
1.164     brouard   882: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard   883: #ifdef _WIN32
                    884: #define DIRSEPARATOR '\\'
                    885: #define CHARSEPARATOR "\\"
                    886: #define ODIRSEPARATOR '/'
                    887: #else
1.126     brouard   888: #define DIRSEPARATOR '/'
                    889: #define CHARSEPARATOR "/"
                    890: #define ODIRSEPARATOR '\\'
                    891: #endif
                    892: 
1.231   ! brouard   893: /* $Id: imach.c,v 1.230 2016/08/22 06:55:53 brouard Exp $ */
1.126     brouard   894: /* $State: Exp $ */
1.196     brouard   895: #include "version.h"
                    896: char version[]=__IMACH_VERSION__;
1.224     brouard   897: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.231   ! brouard   898: char fullversion[]="$Revision: 1.230 $ $Date: 2016/08/22 06:55:53 $"; 
1.126     brouard   899: char strstart[80];
                    900: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard   901: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard   902: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard   903: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                    904: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                    905: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard   906: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                    907: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard   908: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                    909: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                    910: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.224     brouard   911: int ncoveff=0; /* Total number of effective covariates in the model */
1.225     brouard   912: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard   913: int ntveff=0; /**< ntveff number of effective time varying variables */
                    914: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard   915: int cptcov=0; /* Working variable */
1.218     brouard   916: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard   917: int npar=NPARMAX;
                    918: int nlstate=2; /* Number of live states */
                    919: int ndeath=1; /* Number of dead states */
1.130     brouard   920: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard   921: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard   922: int popbased=0;
                    923: 
                    924: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard   925: int maxwav=0; /* Maxim number of waves */
                    926: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                    927: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                    928: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard   929:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard   930: int mle=1, weightopt=0;
1.126     brouard   931: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                    932: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                    933: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                    934:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard   935: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard   936: int selected(int kvar); /* Is covariate kvar selected for printing results */
                    937: 
1.130     brouard   938: double jmean=1; /* Mean space between 2 waves */
1.145     brouard   939: double **matprod2(); /* test */
1.126     brouard   940: double **oldm, **newm, **savm; /* Working pointers to matrices */
                    941: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard   942: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                    943: 
1.136     brouard   944: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard   945: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard   946: FILE *ficlog, *ficrespow;
1.130     brouard   947: int globpr=0; /* Global variable for printing or not */
1.126     brouard   948: double fretone; /* Only one call to likelihood */
1.130     brouard   949: long ipmx=0; /* Number of contributions */
1.126     brouard   950: double sw; /* Sum of weights */
                    951: char filerespow[FILENAMELENGTH];
                    952: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                    953: FILE *ficresilk;
                    954: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                    955: FILE *ficresprobmorprev;
                    956: FILE *fichtm, *fichtmcov; /* Html File */
                    957: FILE *ficreseij;
                    958: char filerese[FILENAMELENGTH];
                    959: FILE *ficresstdeij;
                    960: char fileresstde[FILENAMELENGTH];
                    961: FILE *ficrescveij;
                    962: char filerescve[FILENAMELENGTH];
                    963: FILE  *ficresvij;
                    964: char fileresv[FILENAMELENGTH];
                    965: FILE  *ficresvpl;
                    966: char fileresvpl[FILENAMELENGTH];
                    967: char title[MAXLINE];
1.217     brouard   968: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard   969: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                    970: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                    971: char command[FILENAMELENGTH];
                    972: int  outcmd=0;
                    973: 
1.217     brouard   974: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard   975: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard   976: char filelog[FILENAMELENGTH]; /* Log file */
                    977: char filerest[FILENAMELENGTH];
                    978: char fileregp[FILENAMELENGTH];
                    979: char popfile[FILENAMELENGTH];
                    980: 
                    981: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                    982: 
1.157     brouard   983: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                    984: /* struct timezone tzp; */
                    985: /* extern int gettimeofday(); */
                    986: struct tm tml, *gmtime(), *localtime();
                    987: 
                    988: extern time_t time();
                    989: 
                    990: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                    991: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                    992: struct tm tm;
                    993: 
1.126     brouard   994: char strcurr[80], strfor[80];
                    995: 
                    996: char *endptr;
                    997: long lval;
                    998: double dval;
                    999: 
                   1000: #define NR_END 1
                   1001: #define FREE_ARG char*
                   1002: #define FTOL 1.0e-10
                   1003: 
                   1004: #define NRANSI 
                   1005: #define ITMAX 200 
                   1006: 
                   1007: #define TOL 2.0e-4 
                   1008: 
                   1009: #define CGOLD 0.3819660 
                   1010: #define ZEPS 1.0e-10 
                   1011: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1012: 
                   1013: #define GOLD 1.618034 
                   1014: #define GLIMIT 100.0 
                   1015: #define TINY 1.0e-20 
                   1016: 
                   1017: static double maxarg1,maxarg2;
                   1018: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1019: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1020:   
                   1021: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1022: #define rint(a) floor(a+0.5)
1.166     brouard  1023: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1024: #define mytinydouble 1.0e-16
1.166     brouard  1025: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1026: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1027: /* static double dsqrarg; */
                   1028: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1029: static double sqrarg;
                   1030: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1031: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1032: int agegomp= AGEGOMP;
                   1033: 
                   1034: int imx; 
                   1035: int stepm=1;
                   1036: /* Stepm, step in month: minimum step interpolation*/
                   1037: 
                   1038: int estepm;
                   1039: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1040: 
                   1041: int m,nb;
                   1042: long *num;
1.197     brouard  1043: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1044: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1045:                   covariate for which somebody answered excluding 
                   1046:                   undefined. Usually 2: 0 and 1. */
                   1047: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1048:                             covariate for which somebody answered including 
                   1049:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1050: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1051: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1052: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1053: double *ageexmed,*agecens;
                   1054: double dateintmean=0;
                   1055: 
                   1056: double *weight;
                   1057: int **s; /* Status */
1.141     brouard  1058: double *agedc;
1.145     brouard  1059: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1060:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1061:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.225     brouard  1062: double **coqvar; /* Fixed quantitative covariate iqv */
                   1063: double ***cotvar; /* Time varying covariate itv */
                   1064: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1065: double  idx; 
                   1066: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.231   ! brouard  1067: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
        !          1068: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
        !          1069: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
        !          1070: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
        !          1071: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
        !          1072: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
        !          1073: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
        !          1074: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
        !          1075: 
1.230     brouard  1076: int *Tvarsel; /**< Selected covariates for output */
                   1077: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1078: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1079: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1080: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.197     brouard  1081: int *Tage;
1.227     brouard  1082: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1083: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1084: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1085: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1086: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1087: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1088: int **Tvard;
                   1089: int *Tprod;/**< Gives the k position of the k1 product */
                   1090: int *Tposprod; /**< Gives the k1 product from the k position */
                   1091: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   1092:    if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
                   1093:    Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
                   1094: */
                   1095: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1096: double *lsurv, *lpop, *tpop;
                   1097: 
1.231   ! brouard  1098: #define FD 1; /* Fixed dummy covariate */
        !          1099: #define FQ 2; /* Fixed quantitative covariate */
        !          1100: #define FP 3; /* Fixed product covariate */
        !          1101: #define FPDD 7; /* Fixed product dummy*dummy covariate */
        !          1102: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
        !          1103: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
        !          1104: #define VD 10; /* Varying dummy covariate */
        !          1105: #define VQ 11; /* Varying quantitative covariate */
        !          1106: #define VP 12; /* Varying product covariate */
        !          1107: #define VPDD 13; /* Varying product dummy*dummy covariate */
        !          1108: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
        !          1109: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
        !          1110: #define APFD 16; /* Age product * fixed dummy covariate */
        !          1111: #define APFQ 17; /* Age product * fixed quantitative covariate */
        !          1112: #define APVD 18; /* Age product * varying dummy covariate */
        !          1113: #define APVQ 19; /* Age product * varying quantitative covariate */
        !          1114: 
        !          1115: #define FTYPE 1; /* Fixed covariate */
        !          1116: #define VTYPE 2; /* Varying covariate (loop in wave) */
        !          1117: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
        !          1118: 
        !          1119: struct kmodel{
        !          1120:        int maintype; /* main type */
        !          1121:        int subtype; /* subtype */
        !          1122: };
        !          1123: struct kmodel modell[NCOVMAX];
        !          1124: 
1.143     brouard  1125: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1126: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1127: 
                   1128: /**************** split *************************/
                   1129: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1130: {
                   1131:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1132:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1133:   */ 
                   1134:   char *ss;                            /* pointer */
1.186     brouard  1135:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1136: 
                   1137:   l1 = strlen(path );                  /* length of path */
                   1138:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1139:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1140:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1141:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1142:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1143:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1144:     /* get current working directory */
                   1145:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1146: #ifdef WIN32
                   1147:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1148: #else
                   1149:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1150: #endif
1.126     brouard  1151:       return( GLOCK_ERROR_GETCWD );
                   1152:     }
                   1153:     /* got dirc from getcwd*/
                   1154:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1155:   } else {                             /* strip directory from path */
1.126     brouard  1156:     ss++;                              /* after this, the filename */
                   1157:     l2 = strlen( ss );                 /* length of filename */
                   1158:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1159:     strcpy( name, ss );                /* save file name */
                   1160:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1161:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1162:     printf(" DIRC2 = %s \n",dirc);
                   1163:   }
                   1164:   /* We add a separator at the end of dirc if not exists */
                   1165:   l1 = strlen( dirc );                 /* length of directory */
                   1166:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1167:     dirc[l1] =  DIRSEPARATOR;
                   1168:     dirc[l1+1] = 0; 
                   1169:     printf(" DIRC3 = %s \n",dirc);
                   1170:   }
                   1171:   ss = strrchr( name, '.' );           /* find last / */
                   1172:   if (ss >0){
                   1173:     ss++;
                   1174:     strcpy(ext,ss);                    /* save extension */
                   1175:     l1= strlen( name);
                   1176:     l2= strlen(ss)+1;
                   1177:     strncpy( finame, name, l1-l2);
                   1178:     finame[l1-l2]= 0;
                   1179:   }
                   1180: 
                   1181:   return( 0 );                         /* we're done */
                   1182: }
                   1183: 
                   1184: 
                   1185: /******************************************/
                   1186: 
                   1187: void replace_back_to_slash(char *s, char*t)
                   1188: {
                   1189:   int i;
                   1190:   int lg=0;
                   1191:   i=0;
                   1192:   lg=strlen(t);
                   1193:   for(i=0; i<= lg; i++) {
                   1194:     (s[i] = t[i]);
                   1195:     if (t[i]== '\\') s[i]='/';
                   1196:   }
                   1197: }
                   1198: 
1.132     brouard  1199: char *trimbb(char *out, char *in)
1.137     brouard  1200: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1201:   char *s;
                   1202:   s=out;
                   1203:   while (*in != '\0'){
1.137     brouard  1204:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1205:       in++;
                   1206:     }
                   1207:     *out++ = *in++;
                   1208:   }
                   1209:   *out='\0';
                   1210:   return s;
                   1211: }
                   1212: 
1.187     brouard  1213: /* char *substrchaine(char *out, char *in, char *chain) */
                   1214: /* { */
                   1215: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1216: /*   char *s, *t; */
                   1217: /*   t=in;s=out; */
                   1218: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1219: /*     *out++ = *in++; */
                   1220: /*   } */
                   1221: 
                   1222: /*   /\* *in matches *chain *\/ */
                   1223: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1224: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1225: /*   } */
                   1226: /*   in--; chain--; */
                   1227: /*   while ( (*in != '\0')){ */
                   1228: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1229: /*     *out++ = *in++; */
                   1230: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1231: /*   } */
                   1232: /*   *out='\0'; */
                   1233: /*   out=s; */
                   1234: /*   return out; */
                   1235: /* } */
                   1236: char *substrchaine(char *out, char *in, char *chain)
                   1237: {
                   1238:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1239:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1240: 
                   1241:   char *strloc;
                   1242: 
                   1243:   strcpy (out, in); 
                   1244:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1245:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1246:   if(strloc != NULL){ 
                   1247:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1248:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1249:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1250:   }
                   1251:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1252:   return out;
                   1253: }
                   1254: 
                   1255: 
1.145     brouard  1256: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1257: {
1.187     brouard  1258:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1259:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1260:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1261:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1262:   */
1.160     brouard  1263:   char *s, *t;
1.145     brouard  1264:   t=in;s=in;
                   1265:   while ((*in != occ) && (*in != '\0')){
                   1266:     *alocc++ = *in++;
                   1267:   }
                   1268:   if( *in == occ){
                   1269:     *(alocc)='\0';
                   1270:     s=++in;
                   1271:   }
                   1272:  
                   1273:   if (s == t) {/* occ not found */
                   1274:     *(alocc-(in-s))='\0';
                   1275:     in=s;
                   1276:   }
                   1277:   while ( *in != '\0'){
                   1278:     *blocc++ = *in++;
                   1279:   }
                   1280: 
                   1281:   *blocc='\0';
                   1282:   return t;
                   1283: }
1.137     brouard  1284: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1285: {
1.187     brouard  1286:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1287:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1288:      gives blocc="abcdef2ghi" and alocc="j".
                   1289:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1290:   */
                   1291:   char *s, *t;
                   1292:   t=in;s=in;
                   1293:   while (*in != '\0'){
                   1294:     while( *in == occ){
                   1295:       *blocc++ = *in++;
                   1296:       s=in;
                   1297:     }
                   1298:     *blocc++ = *in++;
                   1299:   }
                   1300:   if (s == t) /* occ not found */
                   1301:     *(blocc-(in-s))='\0';
                   1302:   else
                   1303:     *(blocc-(in-s)-1)='\0';
                   1304:   in=s;
                   1305:   while ( *in != '\0'){
                   1306:     *alocc++ = *in++;
                   1307:   }
                   1308: 
                   1309:   *alocc='\0';
                   1310:   return s;
                   1311: }
                   1312: 
1.126     brouard  1313: int nbocc(char *s, char occ)
                   1314: {
                   1315:   int i,j=0;
                   1316:   int lg=20;
                   1317:   i=0;
                   1318:   lg=strlen(s);
                   1319:   for(i=0; i<= lg; i++) {
                   1320:   if  (s[i] == occ ) j++;
                   1321:   }
                   1322:   return j;
                   1323: }
                   1324: 
1.137     brouard  1325: /* void cutv(char *u,char *v, char*t, char occ) */
                   1326: /* { */
                   1327: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1328: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1329: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1330: /*   int i,lg,j,p=0; */
                   1331: /*   i=0; */
                   1332: /*   lg=strlen(t); */
                   1333: /*   for(j=0; j<=lg-1; j++) { */
                   1334: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1335: /*   } */
1.126     brouard  1336: 
1.137     brouard  1337: /*   for(j=0; j<p; j++) { */
                   1338: /*     (u[j] = t[j]); */
                   1339: /*   } */
                   1340: /*      u[p]='\0'; */
1.126     brouard  1341: 
1.137     brouard  1342: /*    for(j=0; j<= lg; j++) { */
                   1343: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1344: /*   } */
                   1345: /* } */
1.126     brouard  1346: 
1.160     brouard  1347: #ifdef _WIN32
                   1348: char * strsep(char **pp, const char *delim)
                   1349: {
                   1350:   char *p, *q;
                   1351:          
                   1352:   if ((p = *pp) == NULL)
                   1353:     return 0;
                   1354:   if ((q = strpbrk (p, delim)) != NULL)
                   1355:   {
                   1356:     *pp = q + 1;
                   1357:     *q = '\0';
                   1358:   }
                   1359:   else
                   1360:     *pp = 0;
                   1361:   return p;
                   1362: }
                   1363: #endif
                   1364: 
1.126     brouard  1365: /********************** nrerror ********************/
                   1366: 
                   1367: void nrerror(char error_text[])
                   1368: {
                   1369:   fprintf(stderr,"ERREUR ...\n");
                   1370:   fprintf(stderr,"%s\n",error_text);
                   1371:   exit(EXIT_FAILURE);
                   1372: }
                   1373: /*********************** vector *******************/
                   1374: double *vector(int nl, int nh)
                   1375: {
                   1376:   double *v;
                   1377:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1378:   if (!v) nrerror("allocation failure in vector");
                   1379:   return v-nl+NR_END;
                   1380: }
                   1381: 
                   1382: /************************ free vector ******************/
                   1383: void free_vector(double*v, int nl, int nh)
                   1384: {
                   1385:   free((FREE_ARG)(v+nl-NR_END));
                   1386: }
                   1387: 
                   1388: /************************ivector *******************************/
                   1389: int *ivector(long nl,long nh)
                   1390: {
                   1391:   int *v;
                   1392:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1393:   if (!v) nrerror("allocation failure in ivector");
                   1394:   return v-nl+NR_END;
                   1395: }
                   1396: 
                   1397: /******************free ivector **************************/
                   1398: void free_ivector(int *v, long nl, long nh)
                   1399: {
                   1400:   free((FREE_ARG)(v+nl-NR_END));
                   1401: }
                   1402: 
                   1403: /************************lvector *******************************/
                   1404: long *lvector(long nl,long nh)
                   1405: {
                   1406:   long *v;
                   1407:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1408:   if (!v) nrerror("allocation failure in ivector");
                   1409:   return v-nl+NR_END;
                   1410: }
                   1411: 
                   1412: /******************free lvector **************************/
                   1413: void free_lvector(long *v, long nl, long nh)
                   1414: {
                   1415:   free((FREE_ARG)(v+nl-NR_END));
                   1416: }
                   1417: 
                   1418: /******************* imatrix *******************************/
                   1419: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1420:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1421: { 
                   1422:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1423:   int **m; 
                   1424:   
                   1425:   /* allocate pointers to rows */ 
                   1426:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1427:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1428:   m += NR_END; 
                   1429:   m -= nrl; 
                   1430:   
                   1431:   
                   1432:   /* allocate rows and set pointers to them */ 
                   1433:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1434:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1435:   m[nrl] += NR_END; 
                   1436:   m[nrl] -= ncl; 
                   1437:   
                   1438:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1439:   
                   1440:   /* return pointer to array of pointers to rows */ 
                   1441:   return m; 
                   1442: } 
                   1443: 
                   1444: /****************** free_imatrix *************************/
                   1445: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1446:       int **m;
                   1447:       long nch,ncl,nrh,nrl; 
                   1448:      /* free an int matrix allocated by imatrix() */ 
                   1449: { 
                   1450:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1451:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1452: } 
                   1453: 
                   1454: /******************* matrix *******************************/
                   1455: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1456: {
                   1457:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1458:   double **m;
                   1459: 
                   1460:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1461:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1462:   m += NR_END;
                   1463:   m -= nrl;
                   1464: 
                   1465:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1466:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1467:   m[nrl] += NR_END;
                   1468:   m[nrl] -= ncl;
                   1469: 
                   1470:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1471:   return m;
1.145     brouard  1472:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1473: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1474: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1475:    */
                   1476: }
                   1477: 
                   1478: /*************************free matrix ************************/
                   1479: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1480: {
                   1481:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1482:   free((FREE_ARG)(m+nrl-NR_END));
                   1483: }
                   1484: 
                   1485: /******************* ma3x *******************************/
                   1486: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1487: {
                   1488:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1489:   double ***m;
                   1490: 
                   1491:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1492:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1493:   m += NR_END;
                   1494:   m -= nrl;
                   1495: 
                   1496:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1497:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1498:   m[nrl] += NR_END;
                   1499:   m[nrl] -= ncl;
                   1500: 
                   1501:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1502: 
                   1503:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1504:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1505:   m[nrl][ncl] += NR_END;
                   1506:   m[nrl][ncl] -= nll;
                   1507:   for (j=ncl+1; j<=nch; j++) 
                   1508:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1509:   
                   1510:   for (i=nrl+1; i<=nrh; i++) {
                   1511:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1512:     for (j=ncl+1; j<=nch; j++) 
                   1513:       m[i][j]=m[i][j-1]+nlay;
                   1514:   }
                   1515:   return m; 
                   1516:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1517:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1518:   */
                   1519: }
                   1520: 
                   1521: /*************************free ma3x ************************/
                   1522: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1523: {
                   1524:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1525:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1526:   free((FREE_ARG)(m+nrl-NR_END));
                   1527: }
                   1528: 
                   1529: /*************** function subdirf ***********/
                   1530: char *subdirf(char fileres[])
                   1531: {
                   1532:   /* Caution optionfilefiname is hidden */
                   1533:   strcpy(tmpout,optionfilefiname);
                   1534:   strcat(tmpout,"/"); /* Add to the right */
                   1535:   strcat(tmpout,fileres);
                   1536:   return tmpout;
                   1537: }
                   1538: 
                   1539: /*************** function subdirf2 ***********/
                   1540: char *subdirf2(char fileres[], char *preop)
                   1541: {
                   1542:   
                   1543:   /* Caution optionfilefiname is hidden */
                   1544:   strcpy(tmpout,optionfilefiname);
                   1545:   strcat(tmpout,"/");
                   1546:   strcat(tmpout,preop);
                   1547:   strcat(tmpout,fileres);
                   1548:   return tmpout;
                   1549: }
                   1550: 
                   1551: /*************** function subdirf3 ***********/
                   1552: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1553: {
                   1554:   
                   1555:   /* Caution optionfilefiname is hidden */
                   1556:   strcpy(tmpout,optionfilefiname);
                   1557:   strcat(tmpout,"/");
                   1558:   strcat(tmpout,preop);
                   1559:   strcat(tmpout,preop2);
                   1560:   strcat(tmpout,fileres);
                   1561:   return tmpout;
                   1562: }
1.213     brouard  1563:  
                   1564: /*************** function subdirfext ***********/
                   1565: char *subdirfext(char fileres[], char *preop, char *postop)
                   1566: {
                   1567:   
                   1568:   strcpy(tmpout,preop);
                   1569:   strcat(tmpout,fileres);
                   1570:   strcat(tmpout,postop);
                   1571:   return tmpout;
                   1572: }
1.126     brouard  1573: 
1.213     brouard  1574: /*************** function subdirfext3 ***********/
                   1575: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1576: {
                   1577:   
                   1578:   /* Caution optionfilefiname is hidden */
                   1579:   strcpy(tmpout,optionfilefiname);
                   1580:   strcat(tmpout,"/");
                   1581:   strcat(tmpout,preop);
                   1582:   strcat(tmpout,fileres);
                   1583:   strcat(tmpout,postop);
                   1584:   return tmpout;
                   1585: }
                   1586:  
1.162     brouard  1587: char *asc_diff_time(long time_sec, char ascdiff[])
                   1588: {
                   1589:   long sec_left, days, hours, minutes;
                   1590:   days = (time_sec) / (60*60*24);
                   1591:   sec_left = (time_sec) % (60*60*24);
                   1592:   hours = (sec_left) / (60*60) ;
                   1593:   sec_left = (sec_left) %(60*60);
                   1594:   minutes = (sec_left) /60;
                   1595:   sec_left = (sec_left) % (60);
                   1596:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1597:   return ascdiff;
                   1598: }
                   1599: 
1.126     brouard  1600: /***************** f1dim *************************/
                   1601: extern int ncom; 
                   1602: extern double *pcom,*xicom;
                   1603: extern double (*nrfunc)(double []); 
                   1604:  
                   1605: double f1dim(double x) 
                   1606: { 
                   1607:   int j; 
                   1608:   double f;
                   1609:   double *xt; 
                   1610:  
                   1611:   xt=vector(1,ncom); 
                   1612:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1613:   f=(*nrfunc)(xt); 
                   1614:   free_vector(xt,1,ncom); 
                   1615:   return f; 
                   1616: } 
                   1617: 
                   1618: /*****************brent *************************/
                   1619: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1620: {
                   1621:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1622:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1623:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1624:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1625:    * returned function value. 
                   1626:   */
1.126     brouard  1627:   int iter; 
                   1628:   double a,b,d,etemp;
1.159     brouard  1629:   double fu=0,fv,fw,fx;
1.164     brouard  1630:   double ftemp=0.;
1.126     brouard  1631:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1632:   double e=0.0; 
                   1633:  
                   1634:   a=(ax < cx ? ax : cx); 
                   1635:   b=(ax > cx ? ax : cx); 
                   1636:   x=w=v=bx; 
                   1637:   fw=fv=fx=(*f)(x); 
                   1638:   for (iter=1;iter<=ITMAX;iter++) { 
                   1639:     xm=0.5*(a+b); 
                   1640:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1641:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1642:     printf(".");fflush(stdout);
                   1643:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1644: #ifdef DEBUGBRENT
1.126     brouard  1645:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1646:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1647:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1648: #endif
                   1649:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1650:       *xmin=x; 
                   1651:       return fx; 
                   1652:     } 
                   1653:     ftemp=fu;
                   1654:     if (fabs(e) > tol1) { 
                   1655:       r=(x-w)*(fx-fv); 
                   1656:       q=(x-v)*(fx-fw); 
                   1657:       p=(x-v)*q-(x-w)*r; 
                   1658:       q=2.0*(q-r); 
                   1659:       if (q > 0.0) p = -p; 
                   1660:       q=fabs(q); 
                   1661:       etemp=e; 
                   1662:       e=d; 
                   1663:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1664:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1665:       else { 
1.224     brouard  1666:                                d=p/q; 
                   1667:                                u=x+d; 
                   1668:                                if (u-a < tol2 || b-u < tol2) 
                   1669:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1670:       } 
                   1671:     } else { 
                   1672:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1673:     } 
                   1674:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1675:     fu=(*f)(u); 
                   1676:     if (fu <= fx) { 
                   1677:       if (u >= x) a=x; else b=x; 
                   1678:       SHFT(v,w,x,u) 
1.183     brouard  1679:       SHFT(fv,fw,fx,fu) 
                   1680:     } else { 
                   1681:       if (u < x) a=u; else b=u; 
                   1682:       if (fu <= fw || w == x) { 
1.224     brouard  1683:                                v=w; 
                   1684:                                w=u; 
                   1685:                                fv=fw; 
                   1686:                                fw=fu; 
1.183     brouard  1687:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1688:                                v=u; 
                   1689:                                fv=fu; 
1.183     brouard  1690:       } 
                   1691:     } 
1.126     brouard  1692:   } 
                   1693:   nrerror("Too many iterations in brent"); 
                   1694:   *xmin=x; 
                   1695:   return fx; 
                   1696: } 
                   1697: 
                   1698: /****************** mnbrak ***********************/
                   1699: 
                   1700: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1701:            double (*func)(double)) 
1.183     brouard  1702: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1703: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1704: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1705: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1706:    */
1.126     brouard  1707:   double ulim,u,r,q, dum;
                   1708:   double fu; 
1.187     brouard  1709: 
                   1710:   double scale=10.;
                   1711:   int iterscale=0;
                   1712: 
                   1713:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1714:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1715: 
                   1716: 
                   1717:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1718:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1719:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1720:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1721:   /* } */
                   1722: 
1.126     brouard  1723:   if (*fb > *fa) { 
                   1724:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1725:     SHFT(dum,*fb,*fa,dum) 
                   1726:   } 
1.126     brouard  1727:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1728:   *fc=(*func)(*cx); 
1.183     brouard  1729: #ifdef DEBUG
1.224     brouard  1730:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1731:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1732: #endif
1.224     brouard  1733:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1734:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1735:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1736:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1737:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1738:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1739:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1740:       fu=(*func)(u); 
1.163     brouard  1741: #ifdef DEBUG
                   1742:       /* f(x)=A(x-u)**2+f(u) */
                   1743:       double A, fparabu; 
                   1744:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1745:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1746:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1747:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1748:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1749:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1750:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1751:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1752: #endif 
1.184     brouard  1753: #ifdef MNBRAKORIGINAL
1.183     brouard  1754: #else
1.191     brouard  1755: /*       if (fu > *fc) { */
                   1756: /* #ifdef DEBUG */
                   1757: /*       printf("mnbrak4  fu > fc \n"); */
                   1758: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1759: /* #endif */
                   1760: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1761: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1762: /*     dum=u; /\* Shifting c and u *\/ */
                   1763: /*     u = *cx; */
                   1764: /*     *cx = dum; */
                   1765: /*     dum = fu; */
                   1766: /*     fu = *fc; */
                   1767: /*     *fc =dum; */
                   1768: /*       } else { /\* end *\/ */
                   1769: /* #ifdef DEBUG */
                   1770: /*       printf("mnbrak3  fu < fc \n"); */
                   1771: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1772: /* #endif */
                   1773: /*     dum=u; /\* Shifting c and u *\/ */
                   1774: /*     u = *cx; */
                   1775: /*     *cx = dum; */
                   1776: /*     dum = fu; */
                   1777: /*     fu = *fc; */
                   1778: /*     *fc =dum; */
                   1779: /*       } */
1.224     brouard  1780: #ifdef DEBUGMNBRAK
                   1781:                 double A, fparabu; 
                   1782:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1783:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1784:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1785:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1786: #endif
1.191     brouard  1787:       dum=u; /* Shifting c and u */
                   1788:       u = *cx;
                   1789:       *cx = dum;
                   1790:       dum = fu;
                   1791:       fu = *fc;
                   1792:       *fc =dum;
1.183     brouard  1793: #endif
1.162     brouard  1794:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1795: #ifdef DEBUG
1.224     brouard  1796:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1797:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1798: #endif
1.126     brouard  1799:       fu=(*func)(u); 
                   1800:       if (fu < *fc) { 
1.183     brouard  1801: #ifdef DEBUG
1.224     brouard  1802:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1803:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1804: #endif
                   1805:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1806:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1807: #ifdef DEBUG
                   1808:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1809: #endif
                   1810:       } 
1.162     brouard  1811:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1812: #ifdef DEBUG
1.224     brouard  1813:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1814:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1815: #endif
1.126     brouard  1816:       u=ulim; 
                   1817:       fu=(*func)(u); 
1.183     brouard  1818:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1819: #ifdef DEBUG
1.224     brouard  1820:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1821:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1822: #endif
1.126     brouard  1823:       u=(*cx)+GOLD*(*cx-*bx); 
                   1824:       fu=(*func)(u); 
1.224     brouard  1825: #ifdef DEBUG
                   1826:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1827:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1828: #endif
1.183     brouard  1829:     } /* end tests */
1.126     brouard  1830:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  1831:     SHFT(*fa,*fb,*fc,fu) 
                   1832: #ifdef DEBUG
1.224     brouard  1833:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   1834:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  1835: #endif
                   1836:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  1837: } 
                   1838: 
                   1839: /*************** linmin ************************/
1.162     brouard  1840: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   1841: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   1842: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   1843: the value of func at the returned location p . This is actually all accomplished by calling the
                   1844: routines mnbrak and brent .*/
1.126     brouard  1845: int ncom; 
                   1846: double *pcom,*xicom;
                   1847: double (*nrfunc)(double []); 
                   1848:  
1.224     brouard  1849: #ifdef LINMINORIGINAL
1.126     brouard  1850: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  1851: #else
                   1852: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   1853: #endif
1.126     brouard  1854: { 
                   1855:   double brent(double ax, double bx, double cx, 
                   1856:               double (*f)(double), double tol, double *xmin); 
                   1857:   double f1dim(double x); 
                   1858:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   1859:              double *fc, double (*func)(double)); 
                   1860:   int j; 
                   1861:   double xx,xmin,bx,ax; 
                   1862:   double fx,fb,fa;
1.187     brouard  1863: 
1.203     brouard  1864: #ifdef LINMINORIGINAL
                   1865: #else
                   1866:   double scale=10., axs, xxs; /* Scale added for infinity */
                   1867: #endif
                   1868:   
1.126     brouard  1869:   ncom=n; 
                   1870:   pcom=vector(1,n); 
                   1871:   xicom=vector(1,n); 
                   1872:   nrfunc=func; 
                   1873:   for (j=1;j<=n;j++) { 
                   1874:     pcom[j]=p[j]; 
1.202     brouard  1875:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  1876:   } 
1.187     brouard  1877: 
1.203     brouard  1878: #ifdef LINMINORIGINAL
                   1879:   xx=1.;
                   1880: #else
                   1881:   axs=0.0;
                   1882:   xxs=1.;
                   1883:   do{
                   1884:     xx= xxs;
                   1885: #endif
1.187     brouard  1886:     ax=0.;
                   1887:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   1888:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   1889:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   1890:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   1891:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   1892:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   1893:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  1894: #ifdef LINMINORIGINAL
                   1895: #else
                   1896:     if (fx != fx){
1.224     brouard  1897:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   1898:                        printf("|");
                   1899:                        fprintf(ficlog,"|");
1.203     brouard  1900: #ifdef DEBUGLINMIN
1.224     brouard  1901:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  1902: #endif
                   1903:     }
1.224     brouard  1904:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  1905: #endif
                   1906:   
1.191     brouard  1907: #ifdef DEBUGLINMIN
                   1908:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  1909:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  1910: #endif
1.224     brouard  1911: #ifdef LINMINORIGINAL
                   1912: #else
                   1913:        if(fb == fx){ /* Flat function in the direction */
                   1914:                xmin=xx;
                   1915:     *flat=1;
                   1916:        }else{
                   1917:     *flat=0;
                   1918: #endif
                   1919:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  1920:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   1921:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   1922:   /* fmin = f(p[j] + xmin * xi[j]) */
                   1923:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   1924:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  1925: #ifdef DEBUG
1.224     brouard  1926:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   1927:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   1928: #endif
                   1929: #ifdef LINMINORIGINAL
                   1930: #else
                   1931:                        }
1.126     brouard  1932: #endif
1.191     brouard  1933: #ifdef DEBUGLINMIN
                   1934:   printf("linmin end ");
1.202     brouard  1935:   fprintf(ficlog,"linmin end ");
1.191     brouard  1936: #endif
1.126     brouard  1937:   for (j=1;j<=n;j++) { 
1.203     brouard  1938: #ifdef LINMINORIGINAL
                   1939:     xi[j] *= xmin; 
                   1940: #else
                   1941: #ifdef DEBUGLINMIN
                   1942:     if(xxs <1.0)
                   1943:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   1944: #endif
                   1945:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   1946: #ifdef DEBUGLINMIN
                   1947:     if(xxs <1.0)
                   1948:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   1949: #endif
                   1950: #endif
1.187     brouard  1951:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  1952:   } 
1.191     brouard  1953: #ifdef DEBUGLINMIN
1.203     brouard  1954:   printf("\n");
1.191     brouard  1955:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  1956:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  1957:   for (j=1;j<=n;j++) { 
1.202     brouard  1958:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   1959:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   1960:     if(j % ncovmodel == 0){
1.191     brouard  1961:       printf("\n");
1.202     brouard  1962:       fprintf(ficlog,"\n");
                   1963:     }
1.191     brouard  1964:   }
1.203     brouard  1965: #else
1.191     brouard  1966: #endif
1.126     brouard  1967:   free_vector(xicom,1,n); 
                   1968:   free_vector(pcom,1,n); 
                   1969: } 
                   1970: 
                   1971: 
                   1972: /*************** powell ************************/
1.162     brouard  1973: /*
                   1974: Minimization of a function func of n variables. Input consists of an initial starting point
                   1975: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   1976: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   1977: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   1978: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   1979: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   1980:  */
1.224     brouard  1981: #ifdef LINMINORIGINAL
                   1982: #else
                   1983:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  1984:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  1985: #endif
1.126     brouard  1986: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   1987:            double (*func)(double [])) 
                   1988: { 
1.224     brouard  1989: #ifdef LINMINORIGINAL
                   1990:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  1991:              double (*func)(double [])); 
1.224     brouard  1992: #else 
                   1993:  void linmin(double p[], double xi[], int n, double *fret, 
                   1994:                                                 double (*func)(double []),int *flat); 
                   1995: #endif
1.126     brouard  1996:   int i,ibig,j; 
                   1997:   double del,t,*pt,*ptt,*xit;
1.181     brouard  1998:   double directest;
1.126     brouard  1999:   double fp,fptt;
                   2000:   double *xits;
                   2001:   int niterf, itmp;
1.224     brouard  2002: #ifdef LINMINORIGINAL
                   2003: #else
                   2004: 
                   2005:   flatdir=ivector(1,n); 
                   2006:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2007: #endif
1.126     brouard  2008: 
                   2009:   pt=vector(1,n); 
                   2010:   ptt=vector(1,n); 
                   2011:   xit=vector(1,n); 
                   2012:   xits=vector(1,n); 
                   2013:   *fret=(*func)(p); 
                   2014:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2015:   rcurr_time = time(NULL);  
1.126     brouard  2016:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2017:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2018:     ibig=0; 
                   2019:     del=0.0; 
1.157     brouard  2020:     rlast_time=rcurr_time;
                   2021:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2022:     rcurr_time = time(NULL);  
                   2023:     curr_time = *localtime(&rcurr_time);
                   2024:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2025:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2026: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2027:     for (i=1;i<=n;i++) {
1.126     brouard  2028:       printf(" %d %.12f",i, p[i]);
                   2029:       fprintf(ficlog," %d %.12lf",i, p[i]);
                   2030:       fprintf(ficrespow," %.12lf", p[i]);
                   2031:     }
                   2032:     printf("\n");
                   2033:     fprintf(ficlog,"\n");
                   2034:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2035:     if(*iter <=3){
1.157     brouard  2036:       tml = *localtime(&rcurr_time);
                   2037:       strcpy(strcurr,asctime(&tml));
                   2038:       rforecast_time=rcurr_time; 
1.126     brouard  2039:       itmp = strlen(strcurr);
                   2040:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.224     brouard  2041:                                strcurr[itmp-1]='\0';
1.162     brouard  2042:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2043:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2044:       for(niterf=10;niterf<=30;niterf+=10){
1.224     brouard  2045:                                rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2046:                                forecast_time = *localtime(&rforecast_time);
                   2047:                                strcpy(strfor,asctime(&forecast_time));
                   2048:                                itmp = strlen(strfor);
                   2049:                                if(strfor[itmp-1]=='\n')
                   2050:                                        strfor[itmp-1]='\0';
                   2051:                                printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2052:                                fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2053:       }
                   2054:     }
1.187     brouard  2055:     for (i=1;i<=n;i++) { /* For each direction i */
                   2056:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2057:       fptt=(*fret); 
                   2058: #ifdef DEBUG
1.203     brouard  2059:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2060:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2061: #endif
1.203     brouard  2062:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2063:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2064: #ifdef LINMINORIGINAL
1.188     brouard  2065:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2066: #else
                   2067:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2068:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2069: #endif
                   2070:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2071:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2072:                                /* because that direction will be replaced unless the gain del is small */
                   2073:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2074:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2075:                                /* with the new direction. */
                   2076:                                del=fabs(fptt-(*fret)); 
                   2077:                                ibig=i; 
1.126     brouard  2078:       } 
                   2079: #ifdef DEBUG
                   2080:       printf("%d %.12e",i,(*fret));
                   2081:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2082:       for (j=1;j<=n;j++) {
1.224     brouard  2083:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2084:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2085:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2086:       }
                   2087:       for(j=1;j<=n;j++) {
1.225     brouard  2088:                                printf(" p(%d)=%.12e",j,p[j]);
                   2089:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2090:       }
                   2091:       printf("\n");
                   2092:       fprintf(ficlog,"\n");
                   2093: #endif
1.187     brouard  2094:     } /* end loop on each direction i */
                   2095:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2096:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2097:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2098:       for(j=1;j<=n;j++) {
1.225     brouard  2099:                                if(flatdir[j] >0){
                   2100:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2101:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2102:                                }
                   2103:                                /* printf("\n"); */
                   2104:                                /* fprintf(ficlog,"\n"); */
                   2105:                        }
1.182     brouard  2106:     if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /* Did we reach enough precision? */
1.188     brouard  2107:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2108:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2109:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2110:       /* decreased of more than 3.84  */
                   2111:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2112:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2113:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2114:                        
1.188     brouard  2115:       /* Starting the program with initial values given by a former maximization will simply change */
                   2116:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2117:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2118:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2119: #ifdef DEBUG
                   2120:       int k[2],l;
                   2121:       k[0]=1;
                   2122:       k[1]=-1;
                   2123:       printf("Max: %.12e",(*func)(p));
                   2124:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2125:       for (j=1;j<=n;j++) {
                   2126:        printf(" %.12e",p[j]);
                   2127:        fprintf(ficlog," %.12e",p[j]);
                   2128:       }
                   2129:       printf("\n");
                   2130:       fprintf(ficlog,"\n");
                   2131:       for(l=0;l<=1;l++) {
                   2132:        for (j=1;j<=n;j++) {
                   2133:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2134:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2135:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2136:        }
                   2137:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2138:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2139:       }
                   2140: #endif
                   2141: 
1.224     brouard  2142: #ifdef LINMINORIGINAL
                   2143: #else
                   2144:       free_ivector(flatdir,1,n); 
                   2145: #endif
1.126     brouard  2146:       free_vector(xit,1,n); 
                   2147:       free_vector(xits,1,n); 
                   2148:       free_vector(ptt,1,n); 
                   2149:       free_vector(pt,1,n); 
                   2150:       return; 
1.192     brouard  2151:     } /* enough precision */ 
1.126     brouard  2152:     if (*iter == ITMAX) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2153:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2154:       ptt[j]=2.0*p[j]-pt[j]; 
                   2155:       xit[j]=p[j]-pt[j]; 
                   2156:       pt[j]=p[j]; 
                   2157:     } 
1.181     brouard  2158:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2159: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2160:                if (*iter <=4) {
1.225     brouard  2161: #else
                   2162: #endif
1.224     brouard  2163: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2164: #else
1.161     brouard  2165:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2166: #endif
1.162     brouard  2167:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2168:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2169:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2170:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2171:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2172:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2173:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2174:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2175:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2176:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2177:       /* mu² and del² are equal when f3=f1 */
                   2178:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2179:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2180:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2181:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2182: #ifdef NRCORIGINAL
                   2183:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2184: #else
                   2185:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2186:       t= t- del*SQR(fp-fptt);
1.183     brouard  2187: #endif
1.202     brouard  2188:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2189: #ifdef DEBUG
1.181     brouard  2190:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2191:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2192:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2193:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2194:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2195:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2196:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2197:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2198: #endif
1.183     brouard  2199: #ifdef POWELLORIGINAL
                   2200:       if (t < 0.0) { /* Then we use it for new direction */
                   2201: #else
1.182     brouard  2202:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2203:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2204:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2205:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2206:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2207:       } 
1.181     brouard  2208:       if (directest < 0.0) { /* Then we use it for new direction */
                   2209: #endif
1.191     brouard  2210: #ifdef DEBUGLINMIN
1.224     brouard  2211:                                printf("Before linmin in direction P%d-P0\n",n);
                   2212:                                for (j=1;j<=n;j++) {
                   2213:                                        printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2214:                                        fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2215:                                        if(j % ncovmodel == 0){
                   2216:                                                printf("\n");
                   2217:                                                fprintf(ficlog,"\n");
                   2218:                                        }
                   2219:                                }
                   2220: #endif
                   2221: #ifdef LINMINORIGINAL
                   2222:                                linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2223: #else
                   2224:                                linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2225:                                flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2226: #endif
1.224     brouard  2227: 
1.191     brouard  2228: #ifdef DEBUGLINMIN
1.224     brouard  2229:                                for (j=1;j<=n;j++) { 
                   2230:                                        printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2231:                                        fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2232:                                        if(j % ncovmodel == 0){
                   2233:                                                printf("\n");
                   2234:                                                fprintf(ficlog,"\n");
                   2235:                                        }
                   2236:                                }
                   2237: #endif
                   2238:                                for (j=1;j<=n;j++) { 
                   2239:                                        xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2240:                                        xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2241:                                }
                   2242: #ifdef LINMINORIGINAL
                   2243: #else
1.225     brouard  2244:                                for (j=1, flatd=0;j<=n;j++) {
                   2245:                                        if(flatdir[j]>0)
                   2246:                                                flatd++;
                   2247:                                }
                   2248:                                if(flatd >0){
                   2249:                                        printf("%d flat directions\n",flatd);
                   2250:                                        fprintf(ficlog,"%d flat directions\n",flatd);
                   2251:                                        for (j=1;j<=n;j++) { 
                   2252:                                                if(flatdir[j]>0){
                   2253:                                                        printf("%d ",j);
                   2254:                                                        fprintf(ficlog,"%d ",j);
                   2255:                                                }
                   2256:                                        }
                   2257:                                        printf("\n");
                   2258:                                        fprintf(ficlog,"\n");
                   2259:                                }
1.191     brouard  2260: #endif
1.224     brouard  2261:                                printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2262:                                fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2263:                                
1.126     brouard  2264: #ifdef DEBUG
1.224     brouard  2265:                                printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2266:                                fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2267:                                for(j=1;j<=n;j++){
                   2268:                                        printf(" %lf",xit[j]);
                   2269:                                        fprintf(ficlog," %lf",xit[j]);
                   2270:                                }
                   2271:                                printf("\n");
                   2272:                                fprintf(ficlog,"\n");
1.126     brouard  2273: #endif
1.192     brouard  2274:       } /* end of t or directest negative */
1.224     brouard  2275: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2276: #else
1.162     brouard  2277:     } /* end if (fptt < fp)  */
1.192     brouard  2278: #endif
1.225     brouard  2279: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.224     brouard  2280:                } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2281: #else
1.224     brouard  2282: #endif
1.192     brouard  2283:   } /* loop iteration */ 
1.126     brouard  2284: } 
                   2285: 
                   2286: /**** Prevalence limit (stable or period prevalence)  ****************/
                   2287: 
1.203     brouard  2288: double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij)
1.126     brouard  2289: {
1.218     brouard  2290:   /* Computes the prevalence limit in each live state at age x and for covariate ij by left multiplying the unit
1.203     brouard  2291:      matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2292:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2293:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2294:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2295:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2296:   /* Initial matrix pimij */
                   2297:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2298:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2299:   /*  0,                   0                  , 1} */
                   2300:   /*
                   2301:    * and after some iteration: */
                   2302:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2303:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2304:   /*  0,                   0                  , 1} */
                   2305:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2306:   /* {0.51571254859325999, 0.4842874514067399, */
                   2307:   /*  0.51326036147820708, 0.48673963852179264} */
                   2308:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2309: 
1.126     brouard  2310:   int i, ii,j,k;
1.209     brouard  2311:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2312:   /* double **matprod2(); */ /* test */
1.218     brouard  2313:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2314:   double **newm;
1.209     brouard  2315:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2316:   int ncvloop=0;
1.169     brouard  2317:   
1.209     brouard  2318:   min=vector(1,nlstate);
                   2319:   max=vector(1,nlstate);
                   2320:   meandiff=vector(1,nlstate);
                   2321: 
1.218     brouard  2322:        /* Starting with matrix unity */
1.126     brouard  2323:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2324:     for (j=1;j<=nlstate+ndeath;j++){
                   2325:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2326:     }
1.169     brouard  2327:   
                   2328:   cov[1]=1.;
                   2329:   
                   2330:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2331:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2332:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2333:     ncvloop++;
1.126     brouard  2334:     newm=savm;
                   2335:     /* Covariates have to be included here again */
1.138     brouard  2336:     cov[2]=agefin;
1.187     brouard  2337:     if(nagesqr==1)
                   2338:       cov[3]= agefin*agefin;;
1.138     brouard  2339:     for (k=1; k<=cptcovn;k++) {
1.200     brouard  2340:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.218     brouard  2341:                        /* Here comes the value of the covariate 'ij' */
1.200     brouard  2342:       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
1.198     brouard  2343:       /* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); */
1.138     brouard  2344:     }
1.186     brouard  2345:     /*wrong? for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
1.200     brouard  2346:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]*cov[2]; */
                   2347:     for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2];
1.186     brouard  2348:     for (k=1; k<=cptcovprod;k++) /* Useless */
1.200     brouard  2349:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
                   2350:       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
1.138     brouard  2351:     
                   2352:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2353:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2354:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2355:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2356:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2357:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2358:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2359:     
1.126     brouard  2360:     savm=oldm;
                   2361:     oldm=newm;
1.209     brouard  2362: 
                   2363:     for(j=1; j<=nlstate; j++){
                   2364:       max[j]=0.;
                   2365:       min[j]=1.;
                   2366:     }
                   2367:     for(i=1;i<=nlstate;i++){
                   2368:       sumnew=0;
                   2369:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2370:       for(j=1; j<=nlstate; j++){ 
                   2371:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2372:        max[j]=FMAX(max[j],prlim[i][j]);
                   2373:        min[j]=FMIN(min[j],prlim[i][j]);
                   2374:       }
                   2375:     }
                   2376: 
1.126     brouard  2377:     maxmax=0.;
1.209     brouard  2378:     for(j=1; j<=nlstate; j++){
                   2379:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2380:       maxmax=FMAX(maxmax,meandiff[j]);
                   2381:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2382:     } /* j loop */
1.203     brouard  2383:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2384:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2385:     if(maxmax < ftolpl){
1.209     brouard  2386:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2387:       free_vector(min,1,nlstate);
                   2388:       free_vector(max,1,nlstate);
                   2389:       free_vector(meandiff,1,nlstate);
1.126     brouard  2390:       return prlim;
                   2391:     }
1.169     brouard  2392:   } /* age loop */
1.208     brouard  2393:     /* After some age loop it doesn't converge */
1.209     brouard  2394:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2395: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2396:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2397:   free_vector(min,1,nlstate);
                   2398:   free_vector(max,1,nlstate);
                   2399:   free_vector(meandiff,1,nlstate);
1.208     brouard  2400:   
1.169     brouard  2401:   return prlim; /* should not reach here */
1.126     brouard  2402: }
                   2403: 
1.217     brouard  2404: 
                   2405:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2406: 
1.218     brouard  2407:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2408:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2409:  double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij)
1.217     brouard  2410: {
1.218     brouard  2411:   /* Computes the prevalence limit in each live state at age x and covariate ij by left multiplying the unit
1.217     brouard  2412:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2413:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2414:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2415:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2416:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2417:   /* Initial matrix pimij */
                   2418:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2419:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2420:   /*  0,                   0                  , 1} */
                   2421:   /*
                   2422:    * and after some iteration: */
                   2423:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2424:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2425:   /*  0,                   0                  , 1} */
                   2426:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2427:   /* {0.51571254859325999, 0.4842874514067399, */
                   2428:   /*  0.51326036147820708, 0.48673963852179264} */
                   2429:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2430: 
                   2431:   int i, ii,j,k;
                   2432:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2433:   /* double **matprod2(); */ /* test */
                   2434:   double **out, cov[NCOVMAX+1], **bmij();
                   2435:   double **newm;
1.218     brouard  2436:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2437:   double        **oldm, **savm;  /* for use */
                   2438: 
1.217     brouard  2439:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2440:   int ncvloop=0;
                   2441:   
                   2442:   min=vector(1,nlstate);
                   2443:   max=vector(1,nlstate);
                   2444:   meandiff=vector(1,nlstate);
                   2445: 
1.218     brouard  2446:        dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2447:        oldm=oldms; savm=savms;
                   2448: 
                   2449:        /* Starting with matrix unity */
                   2450:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   2451:                for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2452:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2453:     }
                   2454:   
                   2455:   cov[1]=1.;
                   2456:   
                   2457:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2458:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2459:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2460:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2461:     ncvloop++;
1.218     brouard  2462:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2463:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2464:     /* Covariates have to be included here again */
                   2465:     cov[2]=agefin;
                   2466:     if(nagesqr==1)
                   2467:       cov[3]= agefin*agefin;;
                   2468:     for (k=1; k<=cptcovn;k++) {
                   2469:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
                   2470:       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   2471:       /* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); */
                   2472:     }
                   2473:     /*wrong? for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   2474:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]*cov[2]; */
                   2475:     for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2];
                   2476:     for (k=1; k<=cptcovprod;k++) /* Useless */
                   2477:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
                   2478:       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2479:     
                   2480:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2481:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2482:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2483:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2484:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2485:                /* ij should be linked to the correct index of cov */
                   2486:                /* age and covariate values ij are in 'cov', but we need to pass
                   2487:                 * ij for the observed prevalence at age and status and covariate
                   2488:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2489:                 */
                   2490:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2491:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2492:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.217     brouard  2493:     savm=oldm;
                   2494:     oldm=newm;
                   2495:     for(j=1; j<=nlstate; j++){
                   2496:       max[j]=0.;
                   2497:       min[j]=1.;
                   2498:     }
                   2499:     for(j=1; j<=nlstate; j++){ 
                   2500:       for(i=1;i<=nlstate;i++){
1.218     brouard  2501:                                /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2502:                                bprlim[i][j]= newm[i][j];
                   2503:                                max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2504:                                min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2505:       }
                   2506:     }
1.218     brouard  2507:                
1.217     brouard  2508:     maxmax=0.;
                   2509:     for(i=1; i<=nlstate; i++){
                   2510:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2511:       maxmax=FMAX(maxmax,meandiff[i]);
                   2512:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
                   2513:     } /* j loop */
                   2514:     *ncvyear= -( (int)age- (int)agefin);
1.218     brouard  2515:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear);*/
1.217     brouard  2516:     if(maxmax < ftolpl){
1.220     brouard  2517:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2518:       free_vector(min,1,nlstate);
                   2519:       free_vector(max,1,nlstate);
                   2520:       free_vector(meandiff,1,nlstate);
                   2521:       return bprlim;
                   2522:     }
                   2523:   } /* age loop */
                   2524:     /* After some age loop it doesn't converge */
                   2525:   printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
                   2526: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2527:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2528:   free_vector(min,1,nlstate);
                   2529:   free_vector(max,1,nlstate);
                   2530:   free_vector(meandiff,1,nlstate);
                   2531:   
                   2532:   return bprlim; /* should not reach here */
                   2533: }
                   2534: 
1.126     brouard  2535: /*************** transition probabilities ***************/ 
                   2536: 
                   2537: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2538: {
1.138     brouard  2539:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2540:      computes the probability to be observed in state j being in state i by appying the
                   2541:      model to the ncovmodel covariates (including constant and age).
                   2542:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2543:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2544:      ncth covariate in the global vector x is given by the formula:
                   2545:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2546:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2547:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2548:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2549:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2550:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2551:   */
                   2552:   double s1, lnpijopii;
1.126     brouard  2553:   /*double t34;*/
1.164     brouard  2554:   int i,j, nc, ii, jj;
1.126     brouard  2555: 
1.223     brouard  2556:   for(i=1; i<= nlstate; i++){
                   2557:     for(j=1; j<i;j++){
                   2558:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2559:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2560:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2561:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2562:       }
                   2563:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2564:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2565:     }
                   2566:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2567:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2568:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2569:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2570:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2571:       }
                   2572:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2573:     }
                   2574:   }
1.218     brouard  2575:   
1.223     brouard  2576:   for(i=1; i<= nlstate; i++){
                   2577:     s1=0;
                   2578:     for(j=1; j<i; j++){
                   2579:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2580:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2581:     }
                   2582:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2583:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2584:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2585:     }
                   2586:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2587:     ps[i][i]=1./(s1+1.);
                   2588:     /* Computing other pijs */
                   2589:     for(j=1; j<i; j++)
                   2590:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2591:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2592:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2593:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2594:   } /* end i */
1.218     brouard  2595:   
1.223     brouard  2596:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2597:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2598:       ps[ii][jj]=0;
                   2599:       ps[ii][ii]=1;
                   2600:     }
                   2601:   }
1.218     brouard  2602:   
                   2603:   
1.223     brouard  2604:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2605:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2606:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2607:   /*   } */
                   2608:   /*   printf("\n "); */
                   2609:   /* } */
                   2610:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2611:   /*
                   2612:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2613:                goto end;*/
1.223     brouard  2614:   return ps;
1.126     brouard  2615: }
                   2616: 
1.218     brouard  2617: /*************** backward transition probabilities ***************/ 
                   2618: 
                   2619:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2620: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2621:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2622: {
1.222     brouard  2623:   /* Computes the backward probability at age agefin and covariate ij
                   2624:    * and returns in **ps as well as **bmij.
                   2625:    */
1.218     brouard  2626:   int i, ii, j,k;
1.222     brouard  2627:   
                   2628:   double **out, **pmij();
                   2629:   double sumnew=0.;
1.218     brouard  2630:   double agefin;
1.222     brouard  2631:   
                   2632:   double **dnewm, **dsavm, **doldm;
                   2633:   double **bbmij;
                   2634:   
1.218     brouard  2635:   doldm=ddoldms; /* global pointers */
1.222     brouard  2636:   dnewm=ddnewms;
                   2637:   dsavm=ddsavms;
                   2638:   
                   2639:   agefin=cov[2];
                   2640:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
                   2641:      the observed prevalence (with this covariate ij) */
                   2642:   dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate);
                   2643:   /* We do have the matrix Px in savm  and we need pij */
                   2644:   for (j=1;j<=nlstate+ndeath;j++){
                   2645:     sumnew=0.; /* w1 p11 + w2 p21 only on live states */
                   2646:     for (ii=1;ii<=nlstate;ii++){
                   2647:       sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij];
                   2648:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
                   2649:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2650:       if(sumnew >= 1.e-10){
                   2651:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
                   2652:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2653:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
                   2654:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2655:        /* }else */
                   2656:        doldm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2657:       }else{
                   2658:        printf("ii=%d, i=%d, doldm=%lf dsavm=%lf, probs=%lf, sumnew=%lf,agefin=%d\n",ii,j,doldm[ii][j],dsavm[ii][j],prevacurrent[(int)agefin][ii][ij],sumnew, (int)agefin);
                   2659:       }
                   2660:     } /*End ii */
                   2661:   } /* End j, At the end doldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2662:   /* left Product of this diag matrix by dsavm=Px (newm=dsavm*doldm) */
                   2663:   bbmij=matprod2(dnewm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, doldm); /* Bug Valgrind */
                   2664:   /* dsavm=doldm; /\* dsavm is now diag [1/(w_1p1i+w_2 p2i)] but can be overwritten*\/ */
                   2665:   /* doldm=dnewm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2666:   /* dnewm=dsavm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2667:   /* left Product of this matrix by diag matrix of prevalences (savm) */
                   2668:   for (j=1;j<=nlstate+ndeath;j++){
                   2669:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2670:       dsavm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij] : 0.0);
                   2671:     }
                   2672:   } /* End j, At the end oldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2673:   ps=matprod2(doldm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dnewm); /* Bug Valgrind */
                   2674:   /* newm or out is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
                   2675:   /* end bmij */
                   2676:   return ps; 
1.218     brouard  2677: }
1.217     brouard  2678: /*************** transition probabilities ***************/ 
                   2679: 
1.218     brouard  2680: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2681: {
                   2682:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2683:      computes the probability to be observed in state j being in state i by appying the
                   2684:      model to the ncovmodel covariates (including constant and age).
                   2685:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2686:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2687:      ncth covariate in the global vector x is given by the formula:
                   2688:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2689:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2690:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2691:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2692:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2693:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2694:   */
                   2695:   double s1, lnpijopii;
                   2696:   /*double t34;*/
                   2697:   int i,j, nc, ii, jj;
                   2698: 
1.218     brouard  2699:        for(i=1; i<= nlstate; i++){
                   2700:                for(j=1; j<i;j++){
                   2701:                        for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2702:                                /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2703:                                lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2704:                                /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2705:                        }
                   2706:                        ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2707:                        /*      printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2708:                }
                   2709:                for(j=i+1; j<=nlstate+ndeath;j++){
                   2710:                        for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2711:                                /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2712:                                lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2713:                                /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2714:                        }
                   2715:                        ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2716:                }
                   2717:        }
                   2718:        
                   2719:        for(i=1; i<= nlstate; i++){
                   2720:                s1=0;
                   2721:                for(j=1; j<i; j++){
                   2722:                        s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2723:                        /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2724:                }
                   2725:                for(j=i+1; j<=nlstate+ndeath; j++){
                   2726:                        s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2727:                        /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2728:                }
                   2729:                /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2730:                ps[i][i]=1./(s1+1.);
                   2731:                /* Computing other pijs */
                   2732:                for(j=1; j<i; j++)
                   2733:                        ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2734:                for(j=i+1; j<=nlstate+ndeath; j++)
                   2735:                        ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2736:                /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2737:        } /* end i */
                   2738:        
                   2739:        for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2740:                for(jj=1; jj<= nlstate+ndeath; jj++){
                   2741:                        ps[ii][jj]=0;
                   2742:                        ps[ii][ii]=1;
                   2743:                }
                   2744:        }
                   2745:        /* Added for backcast */ /* Transposed matrix too */
                   2746:        for(jj=1; jj<= nlstate+ndeath; jj++){
                   2747:                s1=0.;
                   2748:                for(ii=1; ii<= nlstate+ndeath; ii++){
                   2749:                        s1+=ps[ii][jj];
                   2750:                }
                   2751:                for(ii=1; ii<= nlstate; ii++){
                   2752:                        ps[ii][jj]=ps[ii][jj]/s1;
                   2753:                }
                   2754:        }
                   2755:        /* Transposition */
                   2756:        for(jj=1; jj<= nlstate+ndeath; jj++){
                   2757:                for(ii=jj; ii<= nlstate+ndeath; ii++){
                   2758:                        s1=ps[ii][jj];
                   2759:                        ps[ii][jj]=ps[jj][ii];
                   2760:                        ps[jj][ii]=s1;
                   2761:                }
                   2762:        }
                   2763:        /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2764:        /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2765:        /*      printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2766:        /*   } */
                   2767:        /*   printf("\n "); */
                   2768:        /* } */
                   2769:        /* printf("\n ");printf("%lf ",cov[2]);*/
                   2770:        /*
                   2771:                for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   2772:                goto end;*/
                   2773:        return ps;
1.217     brouard  2774: }
                   2775: 
                   2776: 
1.126     brouard  2777: /**************** Product of 2 matrices ******************/
                   2778: 
1.145     brouard  2779: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  2780: {
                   2781:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   2782:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   2783:   /* in, b, out are matrice of pointers which should have been initialized 
                   2784:      before: only the contents of out is modified. The function returns
                   2785:      a pointer to pointers identical to out */
1.145     brouard  2786:   int i, j, k;
1.126     brouard  2787:   for(i=nrl; i<= nrh; i++)
1.145     brouard  2788:     for(k=ncolol; k<=ncoloh; k++){
                   2789:       out[i][k]=0.;
                   2790:       for(j=ncl; j<=nch; j++)
                   2791:        out[i][k] +=in[i][j]*b[j][k];
                   2792:     }
1.126     brouard  2793:   return out;
                   2794: }
                   2795: 
                   2796: 
                   2797: /************* Higher Matrix Product ***************/
                   2798: 
                   2799: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij )
                   2800: {
1.218     brouard  2801:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  2802:      'nhstepm*hstepm*stepm' months (i.e. until
                   2803:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   2804:      nhstepm*hstepm matrices. 
                   2805:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   2806:      (typically every 2 years instead of every month which is too big 
                   2807:      for the memory).
                   2808:      Model is determined by parameters x and covariates have to be 
                   2809:      included manually here. 
                   2810: 
                   2811:      */
                   2812: 
                   2813:   int i, j, d, h, k;
1.131     brouard  2814:   double **out, cov[NCOVMAX+1];
1.126     brouard  2815:   double **newm;
1.187     brouard  2816:   double agexact;
1.214     brouard  2817:   double agebegin, ageend;
1.126     brouard  2818: 
                   2819:   /* Hstepm could be zero and should return the unit matrix */
                   2820:   for (i=1;i<=nlstate+ndeath;i++)
                   2821:     for (j=1;j<=nlstate+ndeath;j++){
                   2822:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   2823:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   2824:     }
                   2825:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2826:   for(h=1; h <=nhstepm; h++){
                   2827:     for(d=1; d <=hstepm; d++){
                   2828:       newm=savm;
                   2829:       /* Covariates have to be included here again */
                   2830:       cov[1]=1.;
1.214     brouard  2831:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  2832:       cov[2]=agexact;
                   2833:       if(nagesqr==1)
1.227     brouard  2834:        cov[3]= agexact*agexact;
1.131     brouard  2835:       for (k=1; k<=cptcovn;k++) 
1.227     brouard  2836:        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   2837:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.186     brouard  2838:       for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
1.227     brouard  2839:        /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   2840:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2841:       /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
1.145     brouard  2842:       for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
1.227     brouard  2843:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2844:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
                   2845:       
                   2846:       
1.126     brouard  2847:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   2848:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  2849:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  2850:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   2851:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  2852:       /* if((int)age == 70){ */
                   2853:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   2854:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   2855:       /*         printf("%d pmmij ",i); */
                   2856:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2857:       /*           printf("%f ",pmmij[i][j]); */
                   2858:       /*         } */
                   2859:       /*         printf(" oldm "); */
                   2860:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2861:       /*           printf("%f ",oldm[i][j]); */
                   2862:       /*         } */
                   2863:       /*         printf("\n"); */
                   2864:       /*       } */
                   2865:       /* } */
1.126     brouard  2866:       savm=oldm;
                   2867:       oldm=newm;
                   2868:     }
                   2869:     for(i=1; i<=nlstate+ndeath; i++)
                   2870:       for(j=1;j<=nlstate+ndeath;j++) {
1.218     brouard  2871:                                po[i][j][h]=newm[i][j];
                   2872:                                /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  2873:       }
1.128     brouard  2874:     /*printf("h=%d ",h);*/
1.126     brouard  2875:   } /* end h */
1.218     brouard  2876:        /*     printf("\n H=%d \n",h); */
1.126     brouard  2877:   return po;
                   2878: }
                   2879: 
1.217     brouard  2880: /************* Higher Back Matrix Product ***************/
1.218     brouard  2881: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.222     brouard  2882: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij )
1.217     brouard  2883: {
1.218     brouard  2884:   /* Computes the transition matrix starting at age 'age' over
1.217     brouard  2885:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  2886:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   2887:      nhstepm*hstepm matrices.
                   2888:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   2889:      (typically every 2 years instead of every month which is too big
1.217     brouard  2890:      for the memory).
1.218     brouard  2891:      Model is determined by parameters x and covariates have to be
                   2892:      included manually here.
1.217     brouard  2893: 
1.222     brouard  2894:   */
1.217     brouard  2895: 
                   2896:   int i, j, d, h, k;
                   2897:   double **out, cov[NCOVMAX+1];
                   2898:   double **newm;
                   2899:   double agexact;
                   2900:   double agebegin, ageend;
1.222     brouard  2901:   double **oldm, **savm;
1.217     brouard  2902: 
1.222     brouard  2903:   oldm=oldms;savm=savms;
1.217     brouard  2904:   /* Hstepm could be zero and should return the unit matrix */
                   2905:   for (i=1;i<=nlstate+ndeath;i++)
                   2906:     for (j=1;j<=nlstate+ndeath;j++){
                   2907:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   2908:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   2909:     }
                   2910:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2911:   for(h=1; h <=nhstepm; h++){
                   2912:     for(d=1; d <=hstepm; d++){
                   2913:       newm=savm;
                   2914:       /* Covariates have to be included here again */
                   2915:       cov[1]=1.;
                   2916:       agexact=age-((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
                   2917:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   2918:       cov[2]=agexact;
                   2919:       if(nagesqr==1)
1.222     brouard  2920:        cov[3]= agexact*agexact;
1.218     brouard  2921:       for (k=1; k<=cptcovn;k++)
1.222     brouard  2922:        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   2923:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.217     brouard  2924:       for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
1.222     brouard  2925:        /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   2926:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2927:       /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
1.217     brouard  2928:       for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
1.222     brouard  2929:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2930:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
1.218     brouard  2931:                        
                   2932:                        
1.217     brouard  2933:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   2934:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  2935:       /* Careful transposed matrix */
1.222     brouard  2936:       /* age is in cov[2] */
1.218     brouard  2937:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  2938:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  2939:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  2940:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  2941:       /* if((int)age == 70){ */
                   2942:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   2943:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   2944:       /*         printf("%d pmmij ",i); */
                   2945:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2946:       /*           printf("%f ",pmmij[i][j]); */
                   2947:       /*         } */
                   2948:       /*         printf(" oldm "); */
                   2949:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2950:       /*           printf("%f ",oldm[i][j]); */
                   2951:       /*         } */
                   2952:       /*         printf("\n"); */
                   2953:       /*       } */
                   2954:       /* } */
                   2955:       savm=oldm;
                   2956:       oldm=newm;
                   2957:     }
                   2958:     for(i=1; i<=nlstate+ndeath; i++)
                   2959:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  2960:        po[i][j][h]=newm[i][j];
                   2961:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.217     brouard  2962:       }
                   2963:     /*printf("h=%d ",h);*/
                   2964:   } /* end h */
1.222     brouard  2965:   /*     printf("\n H=%d \n",h); */
1.217     brouard  2966:   return po;
                   2967: }
                   2968: 
                   2969: 
1.162     brouard  2970: #ifdef NLOPT
                   2971:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   2972:   double fret;
                   2973:   double *xt;
                   2974:   int j;
                   2975:   myfunc_data *d2 = (myfunc_data *) pd;
                   2976: /* xt = (p1-1); */
                   2977:   xt=vector(1,n); 
                   2978:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   2979: 
                   2980:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   2981:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   2982:   printf("Function = %.12lf ",fret);
                   2983:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   2984:   printf("\n");
                   2985:  free_vector(xt,1,n);
                   2986:   return fret;
                   2987: }
                   2988: #endif
1.126     brouard  2989: 
                   2990: /*************** log-likelihood *************/
                   2991: double func( double *x)
                   2992: {
1.226     brouard  2993:   int i, ii, j, k, mi, d, kk;
                   2994:   int ioffset=0;
                   2995:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   2996:   double **out;
                   2997:   double lli; /* Individual log likelihood */
                   2998:   int s1, s2;
1.228     brouard  2999:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3000:   double bbh, survp;
                   3001:   long ipmx;
                   3002:   double agexact;
                   3003:   /*extern weight */
                   3004:   /* We are differentiating ll according to initial status */
                   3005:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3006:   /*for(i=1;i<imx;i++) 
                   3007:     printf(" %d\n",s[4][i]);
                   3008:   */
1.162     brouard  3009: 
1.226     brouard  3010:   ++countcallfunc;
1.162     brouard  3011: 
1.226     brouard  3012:   cov[1]=1.;
1.126     brouard  3013: 
1.226     brouard  3014:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3015:   ioffset=0;
1.226     brouard  3016:   if(mle==1){
                   3017:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3018:       /* Computes the values of the ncovmodel covariates of the model
                   3019:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3020:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3021:         to be observed in j being in i according to the model.
                   3022:       */
                   3023:       ioffset=2+nagesqr+cptcovage;
                   3024:       /* for (k=1; k<=cptcovn;k++){ /\* Simple and product covariates without age* products *\/ */
                   3025:       for (k=1; k<=ncoveff;k++){ /* Simple and product covariates without age* products */
                   3026:        cov[++ioffset]=covar[Tvar[k]][i];
                   3027:       }
                   3028:       for(iqv=1; iqv <= nqfveff; iqv++){ /* Quantitatives and Fixed covariates */
1.228     brouard  3029:        cov[++ioffset]=coqvar[Tvar[iqv]][i];
1.226     brouard  3030:       }
                   3031: 
                   3032:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3033:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3034:         has been calculated etc */
                   3035:       /* For an individual i, wav[i] gives the number of effective waves */
                   3036:       /* We compute the contribution to Likelihood of each effective transition
                   3037:         mw[mi][i] is real wave of the mi th effectve wave */
                   3038:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3039:         s2=s[mw[mi+1][i]][i];
                   3040:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3041:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3042:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3043:       */
                   3044:       for(mi=1; mi<= wav[i]-1; mi++){
1.231   ! brouard  3045:                                for(itv=1; itv <= ntveff; itv++){ /* Varying dummy covariates */
        !          3046:                                        /* cov[ioffset+itv]=cotvar[mw[mi][i]][Tvar[itv]][i]; /\* Not sure, Tvar V4+V3+V5 Tvaraff ? *\/ */
        !          3047:                                        cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i];
        !          3048:                                }
        !          3049:                                for(iqtv=1; iqtv <= nqtveff; iqtv++){ /* Varying quantitatives covariates */
        !          3050:                                        if(cotqvar[mw[mi][i]][iqtv][i] == -1){
        !          3051:                                                printf("i=%d, mi=%d, iqtv=%d, cotqvar[mw[mi][i]][iqtv][i]=%f",i,mi,iqtv,cotqvar[mw[mi][i]][iqtv][i]);
        !          3052:                                        }
        !          3053:                                        cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i];
        !          3054:                                        /* cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][iqtv][i]; */
        !          3055:                                }
        !          3056:                                /* ioffset=2+nagesqr+cptcovn+nqv+ntv+nqtv; */
        !          3057:                                for (ii=1;ii<=nlstate+ndeath;ii++)
        !          3058:                                        for (j=1;j<=nlstate+ndeath;j++){
        !          3059:                                                oldm[ii][j]=(ii==j ? 1.0 : 0.0);
        !          3060:                                                savm[ii][j]=(ii==j ? 1.0 : 0.0);
        !          3061:                                        }
        !          3062:                                for(d=0; d<dh[mi][i]; d++){
        !          3063:                                        newm=savm;
        !          3064:                                        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
        !          3065:                                        cov[2]=agexact;
        !          3066:                                        if(nagesqr==1)
        !          3067:                                                cov[3]= agexact*agexact;  /* Should be changed here */
        !          3068:                                        for (kk=1; kk<=cptcovage;kk++) {
        !          3069:                                                cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
        !          3070:                                        }
        !          3071:                                        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
        !          3072:                                                                                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
        !          3073:                                        savm=oldm;
        !          3074:                                        oldm=newm;
        !          3075:                                } /* end mult */
1.224     brouard  3076:                                
1.231   ! brouard  3077:                                /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
        !          3078:                                /* But now since version 0.9 we anticipate for bias at large stepm.
        !          3079:                                 * If stepm is larger than one month (smallest stepm) and if the exact delay 
        !          3080:                                 * (in months) between two waves is not a multiple of stepm, we rounded to 
        !          3081:                                 * the nearest (and in case of equal distance, to the lowest) interval but now
        !          3082:                                 * we keep into memory the bias bh[mi][i] and also the previous matrix product
        !          3083:                                 * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
        !          3084:                                 * probability in order to take into account the bias as a fraction of the way
        !          3085:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
        !          3086:                                 * -stepm/2 to stepm/2 .
        !          3087:                                 * For stepm=1 the results are the same as for previous versions of Imach.
        !          3088:                                 * For stepm > 1 the results are less biased than in previous versions. 
        !          3089:                                 */
        !          3090:                                s1=s[mw[mi][i]][i];
        !          3091:                                s2=s[mw[mi+1][i]][i];
        !          3092:                                bbh=(double)bh[mi][i]/(double)stepm; 
        !          3093:                                /* bias bh is positive if real duration
        !          3094:                                 * is higher than the multiple of stepm and negative otherwise.
        !          3095:                                 */
        !          3096:                                /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
        !          3097:                                if( s2 > nlstate){ 
        !          3098:                                        /* i.e. if s2 is a death state and if the date of death is known 
        !          3099:                                                 then the contribution to the likelihood is the probability to 
        !          3100:                                                 die between last step unit time and current  step unit time, 
        !          3101:                                                 which is also equal to probability to die before dh 
        !          3102:                                                 minus probability to die before dh-stepm . 
        !          3103:                                                 In version up to 0.92 likelihood was computed
        !          3104:                                                 as if date of death was unknown. Death was treated as any other
        !          3105:                                                 health state: the date of the interview describes the actual state
        !          3106:                                                 and not the date of a change in health state. The former idea was
        !          3107:                                                 to consider that at each interview the state was recorded
        !          3108:                                                 (healthy, disable or death) and IMaCh was corrected; but when we
        !          3109:                                                 introduced the exact date of death then we should have modified
        !          3110:                                                 the contribution of an exact death to the likelihood. This new
        !          3111:                                                 contribution is smaller and very dependent of the step unit
        !          3112:                                                 stepm. It is no more the probability to die between last interview
        !          3113:                                                 and month of death but the probability to survive from last
        !          3114:                                                 interview up to one month before death multiplied by the
        !          3115:                                                 probability to die within a month. Thanks to Chris
        !          3116:                                                 Jackson for correcting this bug.  Former versions increased
        !          3117:                                                 mortality artificially. The bad side is that we add another loop
        !          3118:                                                 which slows down the processing. The difference can be up to 10%
        !          3119:                                                 lower mortality.
        !          3120:                                        */
        !          3121:                                        /* If, at the beginning of the maximization mostly, the
        !          3122:                                                 cumulative probability or probability to be dead is
        !          3123:                                                 constant (ie = 1) over time d, the difference is equal to
        !          3124:                                                 0.  out[s1][3] = savm[s1][3]: probability, being at state
        !          3125:                                                 s1 at precedent wave, to be dead a month before current
        !          3126:                                                 wave is equal to probability, being at state s1 at
        !          3127:                                                 precedent wave, to be dead at mont of the current
        !          3128:                                                 wave. Then the observed probability (that this person died)
        !          3129:                                                 is null according to current estimated parameter. In fact,
        !          3130:                                                 it should be very low but not zero otherwise the log go to
        !          3131:                                                 infinity.
        !          3132:                                        */
1.183     brouard  3133: /* #ifdef INFINITYORIGINAL */
                   3134: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3135: /* #else */
                   3136: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3137: /*         lli=log(mytinydouble); */
                   3138: /*       else */
                   3139: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3140: /* #endif */
1.226     brouard  3141:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3142:          
1.226     brouard  3143:        } else if  ( s2==-1 ) { /* alive */
                   3144:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3145:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3146:          /*survp += out[s1][j]; */
                   3147:          lli= log(survp);
                   3148:        }
                   3149:        else if  (s2==-4) { 
                   3150:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3151:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3152:          lli= log(survp); 
                   3153:        } 
                   3154:        else if  (s2==-5) { 
                   3155:          for (j=1,survp=0. ; j<=2; j++)  
                   3156:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3157:          lli= log(survp); 
                   3158:        } 
                   3159:        else{
                   3160:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3161:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3162:        } 
                   3163:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3164:        /*if(lli ==000.0)*/
                   3165:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3166:        ipmx +=1;
                   3167:        sw += weight[i];
                   3168:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3169:        /* if (lli < log(mytinydouble)){ */
                   3170:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3171:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3172:        /* } */
                   3173:       } /* end of wave */
                   3174:     } /* end of individual */
                   3175:   }  else if(mle==2){
                   3176:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3177:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3178:       for(mi=1; mi<= wav[i]-1; mi++){
                   3179:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3180:          for (j=1;j<=nlstate+ndeath;j++){
                   3181:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3182:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3183:          }
                   3184:        for(d=0; d<=dh[mi][i]; d++){
                   3185:          newm=savm;
                   3186:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3187:          cov[2]=agexact;
                   3188:          if(nagesqr==1)
                   3189:            cov[3]= agexact*agexact;
                   3190:          for (kk=1; kk<=cptcovage;kk++) {
                   3191:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3192:          }
                   3193:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3194:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3195:          savm=oldm;
                   3196:          oldm=newm;
                   3197:        } /* end mult */
                   3198:       
                   3199:        s1=s[mw[mi][i]][i];
                   3200:        s2=s[mw[mi+1][i]][i];
                   3201:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3202:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3203:        ipmx +=1;
                   3204:        sw += weight[i];
                   3205:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3206:       } /* end of wave */
                   3207:     } /* end of individual */
                   3208:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3209:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3210:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3211:       for(mi=1; mi<= wav[i]-1; mi++){
                   3212:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3213:          for (j=1;j<=nlstate+ndeath;j++){
                   3214:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3215:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3216:          }
                   3217:        for(d=0; d<dh[mi][i]; d++){
                   3218:          newm=savm;
                   3219:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3220:          cov[2]=agexact;
                   3221:          if(nagesqr==1)
                   3222:            cov[3]= agexact*agexact;
                   3223:          for (kk=1; kk<=cptcovage;kk++) {
                   3224:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3225:          }
                   3226:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3227:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3228:          savm=oldm;
                   3229:          oldm=newm;
                   3230:        } /* end mult */
                   3231:       
                   3232:        s1=s[mw[mi][i]][i];
                   3233:        s2=s[mw[mi+1][i]][i];
                   3234:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3235:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3236:        ipmx +=1;
                   3237:        sw += weight[i];
                   3238:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3239:       } /* end of wave */
                   3240:     } /* end of individual */
                   3241:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3242:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3243:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3244:       for(mi=1; mi<= wav[i]-1; mi++){
                   3245:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3246:          for (j=1;j<=nlstate+ndeath;j++){
                   3247:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3248:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3249:          }
                   3250:        for(d=0; d<dh[mi][i]; d++){
                   3251:          newm=savm;
                   3252:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3253:          cov[2]=agexact;
                   3254:          if(nagesqr==1)
                   3255:            cov[3]= agexact*agexact;
                   3256:          for (kk=1; kk<=cptcovage;kk++) {
                   3257:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3258:          }
1.126     brouard  3259:        
1.226     brouard  3260:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3261:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3262:          savm=oldm;
                   3263:          oldm=newm;
                   3264:        } /* end mult */
                   3265:       
                   3266:        s1=s[mw[mi][i]][i];
                   3267:        s2=s[mw[mi+1][i]][i];
                   3268:        if( s2 > nlstate){ 
                   3269:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3270:        } else if  ( s2==-1 ) { /* alive */
                   3271:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3272:            survp += out[s1][j];
                   3273:          lli= log(survp);
                   3274:        }else{
                   3275:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3276:        }
                   3277:        ipmx +=1;
                   3278:        sw += weight[i];
                   3279:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3280: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3281:       } /* end of wave */
                   3282:     } /* end of individual */
                   3283:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3284:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3285:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3286:       for(mi=1; mi<= wav[i]-1; mi++){
                   3287:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3288:          for (j=1;j<=nlstate+ndeath;j++){
                   3289:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3290:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3291:          }
                   3292:        for(d=0; d<dh[mi][i]; d++){
                   3293:          newm=savm;
                   3294:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3295:          cov[2]=agexact;
                   3296:          if(nagesqr==1)
                   3297:            cov[3]= agexact*agexact;
                   3298:          for (kk=1; kk<=cptcovage;kk++) {
                   3299:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3300:          }
1.126     brouard  3301:        
1.226     brouard  3302:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3303:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3304:          savm=oldm;
                   3305:          oldm=newm;
                   3306:        } /* end mult */
                   3307:       
                   3308:        s1=s[mw[mi][i]][i];
                   3309:        s2=s[mw[mi+1][i]][i];
                   3310:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3311:        ipmx +=1;
                   3312:        sw += weight[i];
                   3313:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3314:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3315:       } /* end of wave */
                   3316:     } /* end of individual */
                   3317:   } /* End of if */
                   3318:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3319:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3320:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3321:   return -l;
1.126     brouard  3322: }
                   3323: 
                   3324: /*************** log-likelihood *************/
                   3325: double funcone( double *x)
                   3326: {
1.228     brouard  3327:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3328:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3329:   int ioffset=0;
1.131     brouard  3330:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3331:   double **out;
                   3332:   double lli; /* Individual log likelihood */
                   3333:   double llt;
                   3334:   int s1, s2;
1.228     brouard  3335:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3336: 
1.126     brouard  3337:   double bbh, survp;
1.187     brouard  3338:   double agexact;
1.214     brouard  3339:   double agebegin, ageend;
1.126     brouard  3340:   /*extern weight */
                   3341:   /* We are differentiating ll according to initial status */
                   3342:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3343:   /*for(i=1;i<imx;i++) 
                   3344:     printf(" %d\n",s[4][i]);
                   3345:   */
                   3346:   cov[1]=1.;
                   3347: 
                   3348:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3349:   ioffset=0;
                   3350:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.225     brouard  3351:     ioffset=2+nagesqr+cptcovage;
1.224     brouard  3352:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.231   ! brouard  3353:     for (k=1; k<=ncoveff;k++){ /* Simple and product fixed Dummy covariates without age* products */
1.230     brouard  3354:       cov[++ioffset]=covar[TvarFD[k]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
1.225     brouard  3355:     }
1.231   ! brouard  3356:     for (k=1; k<=nqfveff;k++){ /* Simple and product fixed Quantitative covariates without age* products */
        !          3357:       cov[++ioffset]=coqvar[TvarFQ[k]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*/
1.225     brouard  3358:     }
1.231   ! brouard  3359:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
        !          3360:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
        !          3361:     /* } */
1.225     brouard  3362:     
1.226     brouard  3363:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.231   ! brouard  3364:       for(itv=1; itv <= ntveff; itv++){ /* Varying dummy covariates (single??)*/
        !          3365:                                /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
        !          3366:                                /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
        !          3367:                                k=ioffset-2-nagesqr-cptcovage+itv; /* position in simple model */
        !          3368:                                cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i];
        !          3369:                                /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.225     brouard  3370:       }
                   3371:       for(iqtv=1; iqtv <= nqtveff; iqtv++){ /* Varying quantitatives covariates */
1.231   ! brouard  3372:                                iv=TmodelInvQind[iqtv]; /* Counting the # varying covariate from 1 to ntveff */
        !          3373:                                /* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); */
        !          3374:                                cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i];
1.225     brouard  3375:       }
1.126     brouard  3376:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.231   ! brouard  3377:                                for (j=1;j<=nlstate+ndeath;j++){
        !          3378:                                        oldm[ii][j]=(ii==j ? 1.0 : 0.0);
        !          3379:                                        savm[ii][j]=(ii==j ? 1.0 : 0.0);
        !          3380:                                }
1.214     brouard  3381:       
                   3382:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3383:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3384:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.231   ! brouard  3385:                                /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
        !          3386:                                        and mw[mi+1][i]. dh depends on stepm.*/
        !          3387:                                newm=savm;
        !          3388:                                agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
        !          3389:                                cov[2]=agexact;
        !          3390:                                if(nagesqr==1)
        !          3391:                                        cov[3]= agexact*agexact;
        !          3392:                                for (kk=1; kk<=cptcovage;kk++) {
        !          3393:                                        cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
        !          3394:                                }
        !          3395:                                /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
        !          3396:                                /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
        !          3397:                                out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
        !          3398:                                                                                 1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
        !          3399:                                /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
        !          3400:                                /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
        !          3401:                                savm=oldm;
        !          3402:                                oldm=newm;
1.126     brouard  3403:       } /* end mult */
                   3404:       
                   3405:       s1=s[mw[mi][i]][i];
                   3406:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3407:       /* if(s2==-1){ */
                   3408:       /*       printf(" s1=%d, s2=%d i=%d \n", s1, s2, i); */
                   3409:       /*       /\* exit(1); *\/ */
                   3410:       /* } */
1.126     brouard  3411:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3412:       /* bias is positive if real duration
                   3413:        * is higher than the multiple of stepm and negative otherwise.
                   3414:        */
                   3415:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.225     brouard  3416:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3417:       } else if  ( s2==-1 ) { /* alive */
1.225     brouard  3418:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3419:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3420:        lli= log(survp);
1.126     brouard  3421:       }else if (mle==1){
1.225     brouard  3422:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3423:       } else if(mle==2){
1.225     brouard  3424:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3425:       } else if(mle==3){  /* exponential inter-extrapolation */
1.225     brouard  3426:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3427:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.225     brouard  3428:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3429:       } else{  /* mle=0 back to 1 */
1.225     brouard  3430:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3431:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3432:       } /* End of if */
                   3433:       ipmx +=1;
                   3434:       sw += weight[i];
                   3435:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3436:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3437:       if(globpr){
1.225     brouard  3438:        fprintf(ficresilk,"%9ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3439:  %11.6f %11.6f %11.6f ", \
1.225     brouard  3440:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
                   3441:                2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
                   3442:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3443:          llt +=ll[k]*gipmx/gsw;
                   3444:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3445:        }
                   3446:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3447:       }
                   3448:     } /* end of wave */
                   3449:   } /* end of individual */
                   3450:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3451:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3452:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3453:   if(globpr==0){ /* First time we count the contributions and weights */
                   3454:     gipmx=ipmx;
                   3455:     gsw=sw;
                   3456:   }
                   3457:   return -l;
                   3458: }
                   3459: 
                   3460: 
                   3461: /*************** function likelione ***********/
                   3462: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3463: {
                   3464:   /* This routine should help understanding what is done with 
                   3465:      the selection of individuals/waves and
                   3466:      to check the exact contribution to the likelihood.
                   3467:      Plotting could be done.
                   3468:    */
                   3469:   int k;
                   3470: 
                   3471:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3472:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3473:     strcat(fileresilk,fileresu);
1.126     brouard  3474:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3475:       printf("Problem with resultfile: %s\n", fileresilk);
                   3476:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3477:     }
1.214     brouard  3478:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3479:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3480:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3481:     for(k=1; k<=nlstate; k++) 
                   3482:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3483:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3484:   }
                   3485: 
                   3486:   *fretone=(*funcone)(p);
                   3487:   if(*globpri !=0){
                   3488:     fclose(ficresilk);
1.205     brouard  3489:     if (mle ==0)
                   3490:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3491:     else if(mle >=1)
                   3492:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3493:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3494:     
1.208     brouard  3495:       
                   3496:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3497:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3498: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3499:     }
1.207     brouard  3500:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3501: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3502:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3503: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3504:     fflush(fichtm);
1.205     brouard  3505:   }
1.126     brouard  3506:   return;
                   3507: }
                   3508: 
                   3509: 
                   3510: /*********** Maximum Likelihood Estimation ***************/
                   3511: 
                   3512: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3513: {
1.165     brouard  3514:   int i,j, iter=0;
1.126     brouard  3515:   double **xi;
                   3516:   double fret;
                   3517:   double fretone; /* Only one call to likelihood */
                   3518:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3519: 
                   3520: #ifdef NLOPT
                   3521:   int creturn;
                   3522:   nlopt_opt opt;
                   3523:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3524:   double *lb;
                   3525:   double minf; /* the minimum objective value, upon return */
                   3526:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3527:   myfunc_data dinst, *d = &dinst;
                   3528: #endif
                   3529: 
                   3530: 
1.126     brouard  3531:   xi=matrix(1,npar,1,npar);
                   3532:   for (i=1;i<=npar;i++)
                   3533:     for (j=1;j<=npar;j++)
                   3534:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3535:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3536:   strcpy(filerespow,"POW_"); 
1.126     brouard  3537:   strcat(filerespow,fileres);
                   3538:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3539:     printf("Problem with resultfile: %s\n", filerespow);
                   3540:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3541:   }
                   3542:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3543:   for (i=1;i<=nlstate;i++)
                   3544:     for(j=1;j<=nlstate+ndeath;j++)
                   3545:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3546:   fprintf(ficrespow,"\n");
1.162     brouard  3547: #ifdef POWELL
1.126     brouard  3548:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3549: #endif
1.126     brouard  3550: 
1.162     brouard  3551: #ifdef NLOPT
                   3552: #ifdef NEWUOA
                   3553:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3554: #else
                   3555:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3556: #endif
                   3557:   lb=vector(0,npar-1);
                   3558:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3559:   nlopt_set_lower_bounds(opt, lb);
                   3560:   nlopt_set_initial_step1(opt, 0.1);
                   3561:   
                   3562:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3563:   d->function = func;
                   3564:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3565:   nlopt_set_min_objective(opt, myfunc, d);
                   3566:   nlopt_set_xtol_rel(opt, ftol);
                   3567:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3568:     printf("nlopt failed! %d\n",creturn); 
                   3569:   }
                   3570:   else {
                   3571:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3572:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3573:     iter=1; /* not equal */
                   3574:   }
                   3575:   nlopt_destroy(opt);
                   3576: #endif
1.126     brouard  3577:   free_matrix(xi,1,npar,1,npar);
                   3578:   fclose(ficrespow);
1.203     brouard  3579:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3580:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3581:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3582: 
                   3583: }
                   3584: 
                   3585: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3586: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3587: {
                   3588:   double  **a,**y,*x,pd;
1.203     brouard  3589:   /* double **hess; */
1.164     brouard  3590:   int i, j;
1.126     brouard  3591:   int *indx;
                   3592: 
                   3593:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3594:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3595:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3596:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3597:   double gompertz(double p[]);
1.203     brouard  3598:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3599: 
                   3600:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3601:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3602:   for (i=1;i<=npar;i++){
1.203     brouard  3603:     printf("%d-",i);fflush(stdout);
                   3604:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3605:    
                   3606:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3607:     
                   3608:     /*  printf(" %f ",p[i]);
                   3609:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3610:   }
                   3611:   
                   3612:   for (i=1;i<=npar;i++) {
                   3613:     for (j=1;j<=npar;j++)  {
                   3614:       if (j>i) { 
1.203     brouard  3615:        printf(".%d-%d",i,j);fflush(stdout);
                   3616:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3617:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3618:        
                   3619:        hess[j][i]=hess[i][j];    
                   3620:        /*printf(" %lf ",hess[i][j]);*/
                   3621:       }
                   3622:     }
                   3623:   }
                   3624:   printf("\n");
                   3625:   fprintf(ficlog,"\n");
                   3626: 
                   3627:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3628:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3629:   
                   3630:   a=matrix(1,npar,1,npar);
                   3631:   y=matrix(1,npar,1,npar);
                   3632:   x=vector(1,npar);
                   3633:   indx=ivector(1,npar);
                   3634:   for (i=1;i<=npar;i++)
                   3635:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3636:   ludcmp(a,npar,indx,&pd);
                   3637: 
                   3638:   for (j=1;j<=npar;j++) {
                   3639:     for (i=1;i<=npar;i++) x[i]=0;
                   3640:     x[j]=1;
                   3641:     lubksb(a,npar,indx,x);
                   3642:     for (i=1;i<=npar;i++){ 
                   3643:       matcov[i][j]=x[i];
                   3644:     }
                   3645:   }
                   3646: 
                   3647:   printf("\n#Hessian matrix#\n");
                   3648:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   3649:   for (i=1;i<=npar;i++) { 
                   3650:     for (j=1;j<=npar;j++) { 
1.203     brouard  3651:       printf("%.6e ",hess[i][j]);
                   3652:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  3653:     }
                   3654:     printf("\n");
                   3655:     fprintf(ficlog,"\n");
                   3656:   }
                   3657: 
1.203     brouard  3658:   /* printf("\n#Covariance matrix#\n"); */
                   3659:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   3660:   /* for (i=1;i<=npar;i++) {  */
                   3661:   /*   for (j=1;j<=npar;j++) {  */
                   3662:   /*     printf("%.6e ",matcov[i][j]); */
                   3663:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   3664:   /*   } */
                   3665:   /*   printf("\n"); */
                   3666:   /*   fprintf(ficlog,"\n"); */
                   3667:   /* } */
                   3668: 
1.126     brouard  3669:   /* Recompute Inverse */
1.203     brouard  3670:   /* for (i=1;i<=npar;i++) */
                   3671:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   3672:   /* ludcmp(a,npar,indx,&pd); */
                   3673: 
                   3674:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   3675: 
                   3676:   /* for (j=1;j<=npar;j++) { */
                   3677:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   3678:   /*   x[j]=1; */
                   3679:   /*   lubksb(a,npar,indx,x); */
                   3680:   /*   for (i=1;i<=npar;i++){  */
                   3681:   /*     y[i][j]=x[i]; */
                   3682:   /*     printf("%.3e ",y[i][j]); */
                   3683:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   3684:   /*   } */
                   3685:   /*   printf("\n"); */
                   3686:   /*   fprintf(ficlog,"\n"); */
                   3687:   /* } */
                   3688: 
                   3689:   /* Verifying the inverse matrix */
                   3690: #ifdef DEBUGHESS
                   3691:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  3692: 
1.203     brouard  3693:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   3694:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  3695: 
                   3696:   for (j=1;j<=npar;j++) {
                   3697:     for (i=1;i<=npar;i++){ 
1.203     brouard  3698:       printf("%.2f ",y[i][j]);
                   3699:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  3700:     }
                   3701:     printf("\n");
                   3702:     fprintf(ficlog,"\n");
                   3703:   }
1.203     brouard  3704: #endif
1.126     brouard  3705: 
                   3706:   free_matrix(a,1,npar,1,npar);
                   3707:   free_matrix(y,1,npar,1,npar);
                   3708:   free_vector(x,1,npar);
                   3709:   free_ivector(indx,1,npar);
1.203     brouard  3710:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  3711: 
                   3712: 
                   3713: }
                   3714: 
                   3715: /*************** hessian matrix ****************/
                   3716: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  3717: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  3718:   int i;
                   3719:   int l=1, lmax=20;
1.203     brouard  3720:   double k1,k2, res, fx;
1.132     brouard  3721:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  3722:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   3723:   int k=0,kmax=10;
                   3724:   double l1;
                   3725: 
                   3726:   fx=func(x);
                   3727:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  3728:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  3729:     l1=pow(10,l);
                   3730:     delts=delt;
                   3731:     for(k=1 ; k <kmax; k=k+1){
                   3732:       delt = delta*(l1*k);
                   3733:       p2[theta]=x[theta] +delt;
1.145     brouard  3734:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  3735:       p2[theta]=x[theta]-delt;
                   3736:       k2=func(p2)-fx;
                   3737:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  3738:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  3739:       
1.203     brouard  3740: #ifdef DEBUGHESSII
1.126     brouard  3741:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3742:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3743: #endif
                   3744:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   3745:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   3746:        k=kmax;
                   3747:       }
                   3748:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  3749:        k=kmax; l=lmax*10;
1.126     brouard  3750:       }
                   3751:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   3752:        delts=delt;
                   3753:       }
1.203     brouard  3754:     } /* End loop k */
1.126     brouard  3755:   }
                   3756:   delti[theta]=delts;
                   3757:   return res; 
                   3758:   
                   3759: }
                   3760: 
1.203     brouard  3761: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  3762: {
                   3763:   int i;
1.164     brouard  3764:   int l=1, lmax=20;
1.126     brouard  3765:   double k1,k2,k3,k4,res,fx;
1.132     brouard  3766:   double p2[MAXPARM+1];
1.203     brouard  3767:   int k, kmax=1;
                   3768:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  3769: 
                   3770:   int firstime=0;
1.203     brouard  3771:   
1.126     brouard  3772:   fx=func(x);
1.203     brouard  3773:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  3774:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  3775:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   3776:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  3777:     k1=func(p2)-fx;
                   3778:   
1.203     brouard  3779:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   3780:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  3781:     k2=func(p2)-fx;
                   3782:   
1.203     brouard  3783:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   3784:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  3785:     k3=func(p2)-fx;
                   3786:   
1.203     brouard  3787:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   3788:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  3789:     k4=func(p2)-fx;
1.203     brouard  3790:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   3791:     if(k1*k2*k3*k4 <0.){
1.208     brouard  3792:       firstime=1;
1.203     brouard  3793:       kmax=kmax+10;
1.208     brouard  3794:     }
                   3795:     if(kmax >=10 || firstime ==1){
1.218     brouard  3796:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you may increase ftol=%.2e\n",thetai,thetaj, ftol);
                   3797:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you may increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  3798:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   3799:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   3800:     }
                   3801: #ifdef DEBUGHESSIJ
                   3802:     v1=hess[thetai][thetai];
                   3803:     v2=hess[thetaj][thetaj];
                   3804:     cv12=res;
                   3805:     /* Computing eigen value of Hessian matrix */
                   3806:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   3807:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   3808:     if ((lc2 <0) || (lc1 <0) ){
                   3809:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   3810:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   3811:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   3812:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   3813:     }
1.126     brouard  3814: #endif
                   3815:   }
                   3816:   return res;
                   3817: }
                   3818: 
1.203     brouard  3819:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   3820: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   3821: /* { */
                   3822: /*   int i; */
                   3823: /*   int l=1, lmax=20; */
                   3824: /*   double k1,k2,k3,k4,res,fx; */
                   3825: /*   double p2[MAXPARM+1]; */
                   3826: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   3827: /*   int k=0,kmax=10; */
                   3828: /*   double l1; */
                   3829:   
                   3830: /*   fx=func(x); */
                   3831: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   3832: /*     l1=pow(10,l); */
                   3833: /*     delts=delt; */
                   3834: /*     for(k=1 ; k <kmax; k=k+1){ */
                   3835: /*       delt = delti*(l1*k); */
                   3836: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   3837: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   3838: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   3839: /*       k1=func(p2)-fx; */
                   3840:       
                   3841: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   3842: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   3843: /*       k2=func(p2)-fx; */
                   3844:       
                   3845: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   3846: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   3847: /*       k3=func(p2)-fx; */
                   3848:       
                   3849: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   3850: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   3851: /*       k4=func(p2)-fx; */
                   3852: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   3853: /* #ifdef DEBUGHESSIJ */
                   3854: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   3855: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   3856: /* #endif */
                   3857: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   3858: /*     k=kmax; */
                   3859: /*       } */
                   3860: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   3861: /*     k=kmax; l=lmax*10; */
                   3862: /*       } */
                   3863: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   3864: /*     delts=delt; */
                   3865: /*       } */
                   3866: /*     } /\* End loop k *\/ */
                   3867: /*   } */
                   3868: /*   delti[theta]=delts; */
                   3869: /*   return res;  */
                   3870: /* } */
                   3871: 
                   3872: 
1.126     brouard  3873: /************** Inverse of matrix **************/
                   3874: void ludcmp(double **a, int n, int *indx, double *d) 
                   3875: { 
                   3876:   int i,imax,j,k; 
                   3877:   double big,dum,sum,temp; 
                   3878:   double *vv; 
                   3879:  
                   3880:   vv=vector(1,n); 
                   3881:   *d=1.0; 
                   3882:   for (i=1;i<=n;i++) { 
                   3883:     big=0.0; 
                   3884:     for (j=1;j<=n;j++) 
                   3885:       if ((temp=fabs(a[i][j])) > big) big=temp; 
                   3886:     if (big == 0.0) nrerror("Singular matrix in routine ludcmp"); 
                   3887:     vv[i]=1.0/big; 
                   3888:   } 
                   3889:   for (j=1;j<=n;j++) { 
                   3890:     for (i=1;i<j;i++) { 
                   3891:       sum=a[i][j]; 
                   3892:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   3893:       a[i][j]=sum; 
                   3894:     } 
                   3895:     big=0.0; 
                   3896:     for (i=j;i<=n;i++) { 
                   3897:       sum=a[i][j]; 
                   3898:       for (k=1;k<j;k++) 
                   3899:        sum -= a[i][k]*a[k][j]; 
                   3900:       a[i][j]=sum; 
                   3901:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   3902:        big=dum; 
                   3903:        imax=i; 
                   3904:       } 
                   3905:     } 
                   3906:     if (j != imax) { 
                   3907:       for (k=1;k<=n;k++) { 
                   3908:        dum=a[imax][k]; 
                   3909:        a[imax][k]=a[j][k]; 
                   3910:        a[j][k]=dum; 
                   3911:       } 
                   3912:       *d = -(*d); 
                   3913:       vv[imax]=vv[j]; 
                   3914:     } 
                   3915:     indx[j]=imax; 
                   3916:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   3917:     if (j != n) { 
                   3918:       dum=1.0/(a[j][j]); 
                   3919:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   3920:     } 
                   3921:   } 
                   3922:   free_vector(vv,1,n);  /* Doesn't work */
                   3923: ;
                   3924: } 
                   3925: 
                   3926: void lubksb(double **a, int n, int *indx, double b[]) 
                   3927: { 
                   3928:   int i,ii=0,ip,j; 
                   3929:   double sum; 
                   3930:  
                   3931:   for (i=1;i<=n;i++) { 
                   3932:     ip=indx[i]; 
                   3933:     sum=b[ip]; 
                   3934:     b[ip]=b[i]; 
                   3935:     if (ii) 
                   3936:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   3937:     else if (sum) ii=i; 
                   3938:     b[i]=sum; 
                   3939:   } 
                   3940:   for (i=n;i>=1;i--) { 
                   3941:     sum=b[i]; 
                   3942:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   3943:     b[i]=sum/a[i][i]; 
                   3944:   } 
                   3945: } 
                   3946: 
                   3947: void pstamp(FILE *fichier)
                   3948: {
1.196     brouard  3949:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  3950: }
                   3951: 
                   3952: /************ Frequencies ********************/
1.226     brouard  3953: void  freqsummary(char fileres[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
                   3954:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   3955:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
                   3956: {  /* Some frequencies */
                   3957:   
1.227     brouard  3958:   int i, m, jk, j1, bool, z1,j, k, iv;
1.226     brouard  3959:   int iind=0, iage=0;
                   3960:   int mi; /* Effective wave */
                   3961:   int first;
                   3962:   double ***freq; /* Frequencies */
                   3963:   double *meanq;
                   3964:   double **meanqt;
                   3965:   double *pp, **prop, *posprop, *pospropt;
                   3966:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   3967:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   3968:   double agebegin, ageend;
                   3969:     
                   3970:   pp=vector(1,nlstate);
                   3971:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+3+AGEMARGE); 
                   3972:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   3973:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   3974:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   3975:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   3976:   meanqt=matrix(1,lastpass,1,nqtveff);
                   3977:   strcpy(fileresp,"P_");
                   3978:   strcat(fileresp,fileresu);
                   3979:   /*strcat(fileresphtm,fileresu);*/
                   3980:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   3981:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   3982:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   3983:     exit(0);
                   3984:   }
1.214     brouard  3985: 
1.226     brouard  3986:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   3987:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   3988:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   3989:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   3990:     fflush(ficlog);
                   3991:     exit(70); 
                   3992:   }
                   3993:   else{
                   3994:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.214     brouard  3995: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   3996: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  3997:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   3998:   }
                   3999:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition</h4>\n",fileresphtm, fileresphtm);
1.214     brouard  4000:     
1.226     brouard  4001:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4002:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4003:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4004:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4005:     fflush(ficlog);
                   4006:     exit(70); 
                   4007:   }
                   4008:   else{
                   4009:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.214     brouard  4010: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   4011: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4012:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4013:   }
                   4014:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions by age at begin of transition </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
1.214     brouard  4015: 
1.226     brouard  4016:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+3+AGEMARGE);
                   4017:   j1=0;
1.126     brouard  4018:   
1.227     brouard  4019:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4020:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4021:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.220     brouard  4022: 
1.226     brouard  4023:   first=1;
1.220     brouard  4024: 
1.226     brouard  4025:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4026:      reference=low_education V1=0,V2=0
                   4027:      med_educ                V1=1 V2=0, 
                   4028:      high_educ               V1=0 V2=1
                   4029:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4030:   */
1.126     brouard  4031: 
1.227     brouard  4032:   for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on covariates combination in order of model, excluding quantitatives V4=0, V3=0 for example, fixed or varying covariates */
1.226     brouard  4033:     posproptt=0.;
                   4034:     /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4035:       scanf("%d", i);*/
                   4036:     for (i=-5; i<=nlstate+ndeath; i++)  
                   4037:       for (jk=-5; jk<=nlstate+ndeath; jk++)  
1.231   ! brouard  4038:                                for(m=iagemin; m <= iagemax+3; m++)
        !          4039:                                        freq[i][jk][m]=0;
        !          4040:                
1.226     brouard  4041:     for (i=1; i<=nlstate; i++)  {
                   4042:       for(m=iagemin; m <= iagemax+3; m++)
1.231   ! brouard  4043:                                prop[i][m]=0;
1.226     brouard  4044:       posprop[i]=0;
                   4045:       pospropt[i]=0;
                   4046:     }
1.227     brouard  4047:     /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4048:     /*   meanq[z1]+=0.; */
                   4049:     /*   for(m=1;m<=lastpass;m++){ */
                   4050:     /*         meanqt[m][z1]=0.; */
                   4051:     /*   } */
                   4052:     /* } */
1.231   ! brouard  4053:                
1.226     brouard  4054:     dateintsum=0;
                   4055:     k2cpt=0;
1.227     brouard  4056:     /* For that combination of covariate j1, we count and print the frequencies in one pass */
1.226     brouard  4057:     for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4058:       bool=1;
1.227     brouard  4059:       if(anyvaryingduminmodel==0){ /* If All fixed covariates */
1.231   ! brouard  4060:                                if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
1.227     brouard  4061:          /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4062:          /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4063:          /* } */
1.231   ! brouard  4064:                                        for (z1=1; z1<=cptcoveff; z1++) {  
        !          4065:                                                /* if(Tvaraff[z1] ==-20){ */
        !          4066:                                                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
        !          4067:                                                /* }else  if(Tvaraff[z1] ==-10){ */
        !          4068:                                                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
        !          4069:                                                /* }else  */
        !          4070:                                                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){
        !          4071:                                                        /* Tests if this individual iind responded to j1 (V4=1 V3=0) */
        !          4072:                                                        bool=0;
        !          4073:                                                        /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
        !          4074:                                                                 bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
        !          4075:                                                                 j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
        !          4076:                                                        /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
        !          4077:                                                } /* Onlyf fixed */
        !          4078:                                        } /* end z1 */
        !          4079:                                } /* cptcovn > 0 */
1.227     brouard  4080:       } /* end any */
                   4081:       if (bool==1){ /* We selected an individual iind satisfying combination j1 or all fixed */
1.231   ! brouard  4082:                                /* for(m=firstpass; m<=lastpass; m++){ */
        !          4083:                                for(mi=1; mi<wav[iind];mi++){ /* For that wave */
        !          4084:                                        m=mw[mi][iind];
        !          4085:                                        if(anyvaryingduminmodel==1){ /* Some are varying covariates */
        !          4086:                                                for (z1=1; z1<=cptcoveff; z1++) {
        !          4087:                                                        if( Fixed[Tmodelind[z1]]==1){
        !          4088:                                                                iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
        !          4089:                                                                if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
        !          4090:                                                                        bool=0;
        !          4091:                                                        }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
        !          4092:                                                                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
        !          4093:                                                                        bool=0;
        !          4094:                                                                }
        !          4095:                                                        }
        !          4096:                                                }
        !          4097:                                        }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
        !          4098:                                        /* bool =0 we keep that guy which corresponds to the combination of dummy values */
        !          4099:                                        if(bool==1){
        !          4100:                                                /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
        !          4101:                                                         and mw[mi+1][iind]. dh depends on stepm. */
        !          4102:                                                agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
        !          4103:                                                ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
        !          4104:                                                if(m >=firstpass && m <=lastpass){
        !          4105:                                                        k2=anint[m][iind]+(mint[m][iind]/12.);
        !          4106:                                                        /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
        !          4107:                                                        if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
        !          4108:                                                        if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
        !          4109:                                                        if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
        !          4110:                                                                prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
        !          4111:                                                        if (m<lastpass) {
        !          4112:                                                                /* if(s[m][iind]==4 && s[m+1][iind]==4) */
        !          4113:                                                                /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
        !          4114:                                                                if(s[m][iind]==-1)
        !          4115:                                                                        printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
        !          4116:                                                                freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
        !          4117:                                                                /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
        !          4118:                                                                freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
        !          4119:                                                        }
        !          4120:                                                } /* end if between passes */  
        !          4121:                                                if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99)) {
        !          4122:                                                        dateintsum=dateintsum+k2;
        !          4123:                                                        k2cpt++;
        !          4124:                                                        /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
        !          4125:                                                }
        !          4126:                                        } /* end bool 2 */
        !          4127:                                } /* end m */
1.226     brouard  4128:       } /* end bool */
                   4129:     } /* end iind = 1 to imx */
                   4130:     /* prop[s][age] is feeded for any initial and valid live state as well as
                   4131:        freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
1.231   ! brouard  4132:                
        !          4133:                
1.226     brouard  4134:     /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
                   4135:     pstamp(ficresp);
1.227     brouard  4136:     /* if  (ncoveff>0) { */
                   4137:     if  (cptcoveff>0) {
1.226     brouard  4138:       fprintf(ficresp, "\n#********** Variable "); 
                   4139:       fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4140:       fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
1.227     brouard  4141:       for (z1=1; z1<=cptcoveff; z1++){
1.231   ! brouard  4142:                                fprintf(ficresp, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
        !          4143:                                fprintf(ficresphtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
        !          4144:                                fprintf(ficresphtmfr, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.226     brouard  4145:       }
                   4146:       fprintf(ficresp, "**********\n#");
                   4147:       fprintf(ficresphtm, "**********</h3>\n");
                   4148:       fprintf(ficresphtmfr, "**********</h3>\n");
                   4149:       fprintf(ficlog, "\n#********** Variable "); 
1.227     brouard  4150:       for (z1=1; z1<=cptcoveff; z1++) fprintf(ficlog, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.226     brouard  4151:       fprintf(ficlog, "**********\n");
                   4152:     }
                   4153:     fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
                   4154:     for(i=1; i<=nlstate;i++) {
                   4155:       fprintf(ficresp, " Age Prev(%d) N(%d) N",i,i);
                   4156:       fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4157:     }
                   4158:     fprintf(ficresp, "\n");
                   4159:     fprintf(ficresphtm, "\n");
1.231   ! brouard  4160:                
1.226     brouard  4161:     /* Header of frequency table by age */
                   4162:     fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4163:     fprintf(ficresphtmfr,"<th>Age</th> ");
                   4164:     for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4165:       for(m=-1; m <=nlstate+ndeath; m++){
1.231   ! brouard  4166:                                if(jk!=0 && m!=0)
        !          4167:                                        fprintf(ficresphtmfr,"<th>%d%d</th> ",jk,m);
1.226     brouard  4168:       }
                   4169:     }
                   4170:     fprintf(ficresphtmfr, "\n");
1.231   ! brouard  4171:                
1.226     brouard  4172:     /* For each age */
                   4173:     for(iage=iagemin; iage <= iagemax+3; iage++){
                   4174:       fprintf(ficresphtm,"<tr>");
                   4175:       if(iage==iagemax+1){
1.231   ! brouard  4176:                                fprintf(ficlog,"1");
        !          4177:                                fprintf(ficresphtmfr,"<tr><th>0</th> ");
1.226     brouard  4178:       }else if(iage==iagemax+2){
1.231   ! brouard  4179:                                fprintf(ficlog,"0");
        !          4180:                                fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
1.226     brouard  4181:       }else if(iage==iagemax+3){
1.231   ! brouard  4182:                                fprintf(ficlog,"Total");
        !          4183:                                fprintf(ficresphtmfr,"<tr><th>Total</th> ");
1.226     brouard  4184:       }else{
1.231   ! brouard  4185:                                if(first==1){
        !          4186:                                        first=0;
        !          4187:                                        printf("See log file for details...\n");
        !          4188:                                }
        !          4189:                                fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
        !          4190:                                fprintf(ficlog,"Age %d", iage);
1.226     brouard  4191:       }
                   4192:       for(jk=1; jk <=nlstate ; jk++){
1.231   ! brouard  4193:                                for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
        !          4194:                                        pp[jk] += freq[jk][m][iage]; 
1.226     brouard  4195:       }
                   4196:       for(jk=1; jk <=nlstate ; jk++){
1.231   ! brouard  4197:                                for(m=-1, pos=0; m <=0 ; m++)
        !          4198:                                        pos += freq[jk][m][iage];
        !          4199:                                if(pp[jk]>=1.e-10){
        !          4200:                                        if(first==1){
        !          4201:                                                printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
        !          4202:                                        }
        !          4203:                                        fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
        !          4204:                                }else{
        !          4205:                                        if(first==1)
        !          4206:                                                printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
        !          4207:                                        fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
        !          4208:                                }
1.226     brouard  4209:       }
1.231   ! brouard  4210:                        
1.226     brouard  4211:       for(jk=1; jk <=nlstate ; jk++){ 
1.231   ! brouard  4212:                                /* posprop[jk]=0; */
        !          4213:                                for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
        !          4214:                                        pp[jk] += freq[jk][m][iage];
1.226     brouard  4215:       }        /* pp[jk] is the total number of transitions starting from state jk and any ending status until this age */
1.231   ! brouard  4216:                        
1.226     brouard  4217:       for(jk=1,pos=0, pospropta=0.; jk <=nlstate ; jk++){
1.231   ! brouard  4218:                                pos += pp[jk]; /* pos is the total number of transitions until this age */
        !          4219:                                posprop[jk] += prop[jk][iage]; /* prop is the number of transitions from a live state
        !          4220:                                                                                                                                                                        from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
        !          4221:                                pospropta += prop[jk][iage]; /* prop is the number of transitions from a live state
        !          4222:                                                                                                                                                                from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
1.226     brouard  4223:       }
                   4224:       for(jk=1; jk <=nlstate ; jk++){
1.231   ! brouard  4225:                                if(pos>=1.e-5){
        !          4226:                                        if(first==1)
        !          4227:                                                printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
        !          4228:                                        fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
        !          4229:                                }else{
        !          4230:                                        if(first==1)
        !          4231:                                                printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
        !          4232:                                        fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
        !          4233:                                }
        !          4234:                                if( iage <= iagemax){
        !          4235:                                        if(pos>=1.e-5){
        !          4236:                                                fprintf(ficresp," %d %.5f %.0f %.0f",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
        !          4237:                                                fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
        !          4238:                                                /*probs[iage][jk][j1]= pp[jk]/pos;*/
        !          4239:                                                /*printf("\niage=%d jk=%d j1=%d %.5f %.0f %.0f %f",iage,jk,j1,pp[jk]/pos, pp[jk],pos,probs[iage][jk][j1]);*/
        !          4240:                                        }
        !          4241:                                        else{
        !          4242:                                                fprintf(ficresp," %d NaNq %.0f %.0f",iage,prop[jk][iage],pospropta);
        !          4243:                                                fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[jk][iage],pospropta);
        !          4244:                                        }
        !          4245:                                }
        !          4246:                                pospropt[jk] +=posprop[jk];
1.226     brouard  4247:       } /* end loop jk */
                   4248:       /* pospropt=0.; */
                   4249:       for(jk=-1; jk <=nlstate+ndeath; jk++){
1.231   ! brouard  4250:                                for(m=-1; m <=nlstate+ndeath; m++){
        !          4251:                                        if(freq[jk][m][iage] !=0 ) { /* minimizing output */
        !          4252:                                                if(first==1){
        !          4253:                                                        printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]);
        !          4254:                                                }
        !          4255:                                                fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iage]);
        !          4256:                                        }
        !          4257:                                        if(jk!=0 && m!=0)
        !          4258:                                                fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[jk][m][iage]);
        !          4259:                                }
1.226     brouard  4260:       } /* end loop jk */
                   4261:       posproptt=0.; 
                   4262:       for(jk=1; jk <=nlstate; jk++){
1.231   ! brouard  4263:                                posproptt += pospropt[jk];
1.226     brouard  4264:       }
                   4265:       fprintf(ficresphtmfr,"</tr>\n ");
                   4266:       if(iage <= iagemax){
1.231   ! brouard  4267:                                fprintf(ficresp,"\n");
        !          4268:                                fprintf(ficresphtm,"</tr>\n");
1.226     brouard  4269:       }
                   4270:       if(first==1)
1.231   ! brouard  4271:                                printf("Others in log...\n");
1.226     brouard  4272:       fprintf(ficlog,"\n");
                   4273:     } /* end loop age iage */
                   4274:     fprintf(ficresphtm,"<tr><th>Tot</th>");
                   4275:     for(jk=1; jk <=nlstate ; jk++){
                   4276:       if(posproptt < 1.e-5){
1.231   ! brouard  4277:                                fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[jk],posproptt);   
1.226     brouard  4278:       }else{
1.231   ! brouard  4279:                                fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[jk]/posproptt,pospropt[jk],posproptt);    
1.226     brouard  4280:       }
                   4281:     }
                   4282:     fprintf(ficresphtm,"</tr>\n");
                   4283:     fprintf(ficresphtm,"</table>\n");
                   4284:     fprintf(ficresphtmfr,"</table>\n");
                   4285:     if(posproptt < 1.e-5){
                   4286:       fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4287:       fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4288:       fprintf(ficres,"\n  This combination (%d) is not valid and no result will be produced\n\n",j1);
                   4289:       invalidvarcomb[j1]=1;
                   4290:     }else{
                   4291:       fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4292:       invalidvarcomb[j1]=0;
                   4293:     }
                   4294:     fprintf(ficresphtmfr,"</table>\n");
                   4295:   } /* end selected combination of covariate j1 */
                   4296:   dateintmean=dateintsum/k2cpt; 
1.231   ! brouard  4297:        
1.226     brouard  4298:   fclose(ficresp);
                   4299:   fclose(ficresphtm);
                   4300:   fclose(ficresphtmfr);
                   4301:   free_vector(meanq,1,nqfveff);
                   4302:   free_matrix(meanqt,1,lastpass,1,nqtveff);
                   4303:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+3+AGEMARGE);
                   4304:   free_vector(pospropt,1,nlstate);
                   4305:   free_vector(posprop,1,nlstate);
                   4306:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+3+AGEMARGE);
                   4307:   free_vector(pp,1,nlstate);
                   4308:   /* End of freqsummary */
                   4309: }
1.126     brouard  4310: 
                   4311: /************ Prevalence ********************/
1.227     brouard  4312: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4313: {  
                   4314:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4315:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4316:      We still use firstpass and lastpass as another selection.
                   4317:   */
1.126     brouard  4318:  
1.227     brouard  4319:   int i, m, jk, j1, bool, z1,j, iv;
                   4320:   int mi; /* Effective wave */
                   4321:   int iage;
                   4322:   double agebegin, ageend;
                   4323: 
                   4324:   double **prop;
                   4325:   double posprop; 
                   4326:   double  y2; /* in fractional years */
                   4327:   int iagemin, iagemax;
                   4328:   int first; /** to stop verbosity which is redirected to log file */
                   4329: 
                   4330:   iagemin= (int) agemin;
                   4331:   iagemax= (int) agemax;
                   4332:   /*pp=vector(1,nlstate);*/
                   4333:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+3+AGEMARGE); 
                   4334:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4335:   j1=0;
1.222     brouard  4336:   
1.227     brouard  4337:   /*j=cptcoveff;*/
                   4338:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4339:   
1.227     brouard  4340:   first=1;
                   4341:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4342:     for (i=1; i<=nlstate; i++)  
                   4343:       for(iage=iagemin-AGEMARGE; iage <= iagemax+3+AGEMARGE; iage++)
                   4344:        prop[i][iage]=0.0;
                   4345:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4346:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4347:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4348:     
                   4349:     for (i=1; i<=imx; i++) { /* Each individual */
                   4350:       bool=1;
                   4351:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4352:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4353:        m=mw[mi][i];
                   4354:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4355:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4356:        for (z1=1; z1<=cptcoveff; z1++){
                   4357:          if( Fixed[Tmodelind[z1]]==1){
                   4358:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4359:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4360:              bool=0;
                   4361:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4362:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4363:              bool=0;
                   4364:            }
                   4365:        }
                   4366:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4367:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4368:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4369:          if(m >=firstpass && m <=lastpass){
                   4370:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4371:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4372:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   4373:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
                   4374:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+3+AGEMARGE){
                   4375:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   4376:                exit(1);
                   4377:              }
                   4378:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   4379:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   4380:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   4381:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   4382:              } /* end valid statuses */ 
                   4383:            } /* end selection of dates */
                   4384:          } /* end selection of waves */
                   4385:        } /* end bool */
                   4386:       } /* end wave */
                   4387:     } /* end individual */
                   4388:     for(i=iagemin; i <= iagemax+3; i++){  
                   4389:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   4390:        posprop += prop[jk][i]; 
                   4391:       } 
                   4392:       
                   4393:       for(jk=1; jk <=nlstate ; jk++){      
                   4394:        if( i <=  iagemax){ 
                   4395:          if(posprop>=1.e-5){ 
                   4396:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   4397:          } else{
                   4398:            if(first==1){
                   4399:              first=0;
                   4400:              printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,j1,probs[i][jk][j1]);
                   4401:            }
                   4402:          }
                   4403:        } 
                   4404:       }/* end jk */ 
                   4405:     }/* end i */ 
1.222     brouard  4406:      /*} *//* end i1 */
1.227     brouard  4407:   } /* end j1 */
1.222     brouard  4408:   
1.227     brouard  4409:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   4410:   /*free_vector(pp,1,nlstate);*/
                   4411:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+3+AGEMARGE);
                   4412: }  /* End of prevalence */
1.126     brouard  4413: 
                   4414: /************* Waves Concatenation ***************/
                   4415: 
                   4416: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   4417: {
                   4418:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   4419:      Death is a valid wave (if date is known).
                   4420:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   4421:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4422:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  4423:   */
1.126     brouard  4424: 
1.224     brouard  4425:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  4426:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   4427:      double sum=0., jmean=0.;*/
1.224     brouard  4428:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  4429:   int j, k=0,jk, ju, jl;
                   4430:   double sum=0.;
                   4431:   first=0;
1.214     brouard  4432:   firstwo=0;
1.217     brouard  4433:   firsthree=0;
1.218     brouard  4434:   firstfour=0;
1.164     brouard  4435:   jmin=100000;
1.126     brouard  4436:   jmax=-1;
                   4437:   jmean=0.;
1.224     brouard  4438: 
                   4439: /* Treating live states */
1.214     brouard  4440:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  4441:     mi=0;  /* First valid wave */
1.227     brouard  4442:     mli=0; /* Last valid wave */
1.126     brouard  4443:     m=firstpass;
1.214     brouard  4444:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  4445:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   4446:        mli=m-1;/* mw[++mi][i]=m-1; */
                   4447:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   4448:        mw[++mi][i]=m;
                   4449:        mli=m;
1.224     brouard  4450:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   4451:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  4452:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  4453:       }
1.227     brouard  4454:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  4455: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  4456:        break;
1.224     brouard  4457: #else
1.227     brouard  4458:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   4459:          if(firsthree == 0){
                   4460:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4461:            firsthree=1;
                   4462:          }
                   4463:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4464:          mw[++mi][i]=m;
                   4465:          mli=m;
                   4466:        }
                   4467:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   4468:          nbwarn++;
                   4469:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   4470:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4471:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4472:          }
                   4473:          break;
                   4474:        }
                   4475:        break;
1.224     brouard  4476: #endif
1.227     brouard  4477:       }/* End m >= lastpass */
1.126     brouard  4478:     }/* end while */
1.224     brouard  4479: 
1.227     brouard  4480:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  4481:     /* After last pass */
1.224     brouard  4482: /* Treating death states */
1.214     brouard  4483:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  4484:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   4485:       /* } */
1.126     brouard  4486:       mi++;    /* Death is another wave */
                   4487:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  4488:       /* Only death is a correct wave */
1.126     brouard  4489:       mw[mi][i]=m;
1.224     brouard  4490:     }
                   4491: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.227     brouard  4492:     else if ((int) andc[i] != 9999) { /* Status is negative. A death occured after lastpass, we can't take it into account because of potential bias */
1.216     brouard  4493:       /* m++; */
                   4494:       /* mi++; */
                   4495:       /* s[m][i]=nlstate+1;  /\* We are setting the status to the last of non live state *\/ */
                   4496:       /* mw[mi][i]=m; */
1.218     brouard  4497:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  4498:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   4499:          nbwarn++;
                   4500:          if(firstfiv==0){
                   4501:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4502:            firstfiv=1;
                   4503:          }else{
                   4504:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4505:          }
                   4506:        }else{ /* Death occured afer last wave potential bias */
                   4507:          nberr++;
                   4508:          if(firstwo==0){
                   4509:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4510:            firstwo=1;
                   4511:          }
                   4512:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4513:        }
1.218     brouard  4514:       }else{ /* end date of interview is known */
1.227     brouard  4515:        /* death is known but not confirmed by death status at any wave */
                   4516:        if(firstfour==0){
                   4517:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4518:          firstfour=1;
                   4519:        }
                   4520:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  4521:       }
1.224     brouard  4522:     } /* end if date of death is known */
                   4523: #endif
                   4524:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   4525:     /* wav[i]=mw[mi][i]; */
1.126     brouard  4526:     if(mi==0){
                   4527:       nbwarn++;
                   4528:       if(first==0){
1.227     brouard  4529:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   4530:        first=1;
1.126     brouard  4531:       }
                   4532:       if(first==1){
1.227     brouard  4533:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  4534:       }
                   4535:     } /* end mi==0 */
                   4536:   } /* End individuals */
1.214     brouard  4537:   /* wav and mw are no more changed */
1.223     brouard  4538:        
1.214     brouard  4539:   
1.126     brouard  4540:   for(i=1; i<=imx; i++){
                   4541:     for(mi=1; mi<wav[i];mi++){
                   4542:       if (stepm <=0)
1.227     brouard  4543:        dh[mi][i]=1;
1.126     brouard  4544:       else{
1.227     brouard  4545:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death */
                   4546:          if (agedc[i] < 2*AGESUP) {
                   4547:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   4548:            if(j==0) j=1;  /* Survives at least one month after exam */
                   4549:            else if(j<0){
                   4550:              nberr++;
                   4551:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4552:              j=1; /* Temporary Dangerous patch */
                   4553:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   4554:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4555:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   4556:            }
                   4557:            k=k+1;
                   4558:            if (j >= jmax){
                   4559:              jmax=j;
                   4560:              ijmax=i;
                   4561:            }
                   4562:            if (j <= jmin){
                   4563:              jmin=j;
                   4564:              ijmin=i;
                   4565:            }
                   4566:            sum=sum+j;
                   4567:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   4568:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   4569:          }
                   4570:        }
                   4571:        else{
                   4572:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  4573: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  4574:                                        
1.227     brouard  4575:          k=k+1;
                   4576:          if (j >= jmax) {
                   4577:            jmax=j;
                   4578:            ijmax=i;
                   4579:          }
                   4580:          else if (j <= jmin){
                   4581:            jmin=j;
                   4582:            ijmin=i;
                   4583:          }
                   4584:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   4585:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   4586:          if(j<0){
                   4587:            nberr++;
                   4588:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4589:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4590:          }
                   4591:          sum=sum+j;
                   4592:        }
                   4593:        jk= j/stepm;
                   4594:        jl= j -jk*stepm;
                   4595:        ju= j -(jk+1)*stepm;
                   4596:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   4597:          if(jl==0){
                   4598:            dh[mi][i]=jk;
                   4599:            bh[mi][i]=0;
                   4600:          }else{ /* We want a negative bias in order to only have interpolation ie
                   4601:                  * to avoid the price of an extra matrix product in likelihood */
                   4602:            dh[mi][i]=jk+1;
                   4603:            bh[mi][i]=ju;
                   4604:          }
                   4605:        }else{
                   4606:          if(jl <= -ju){
                   4607:            dh[mi][i]=jk;
                   4608:            bh[mi][i]=jl;       /* bias is positive if real duration
                   4609:                                 * is higher than the multiple of stepm and negative otherwise.
                   4610:                                 */
                   4611:          }
                   4612:          else{
                   4613:            dh[mi][i]=jk+1;
                   4614:            bh[mi][i]=ju;
                   4615:          }
                   4616:          if(dh[mi][i]==0){
                   4617:            dh[mi][i]=1; /* At least one step */
                   4618:            bh[mi][i]=ju; /* At least one step */
                   4619:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   4620:          }
                   4621:        } /* end if mle */
1.126     brouard  4622:       }
                   4623:     } /* end wave */
                   4624:   }
                   4625:   jmean=sum/k;
                   4626:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  4627:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  4628: }
1.126     brouard  4629: 
                   4630: /*********** Tricode ****************************/
1.220     brouard  4631:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.126     brouard  4632: {
1.144     brouard  4633:   /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   4634:   /*     Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
1.169     brouard  4635:    * Boring subroutine which should only output nbcode[Tvar[j]][k]
1.224     brouard  4636:    * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   4637:    * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
1.144     brouard  4638:   */
1.130     brouard  4639: 
1.145     brouard  4640:   int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
1.136     brouard  4641:   int modmaxcovj=0; /* Modality max of covariates j */
1.145     brouard  4642:   int cptcode=0; /* Modality max of covariates j */
                   4643:   int modmincovj=0; /* Modality min of covariates j */
                   4644: 
                   4645: 
1.220     brouard  4646:   /* cptcoveff=0;  */
1.224     brouard  4647:        /* *cptcov=0; */
1.126     brouard  4648:  
1.144     brouard  4649:   for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  4650: 
1.224     brouard  4651:   /* Loop on covariates without age and products and no quantitative variable */
                   4652:   /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
1.227     brouard  4653:   for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   4654:     for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   4655:     if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   4656:       switch(Fixed[k]) {
                   4657:       case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
1.231   ! brouard  4658:                                for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
        !          4659:                                        ij=(int)(covar[Tvar[k]][i]);
        !          4660:                                        /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
        !          4661:                                         * If product of Vn*Vm, still boolean *:
        !          4662:                                         * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
        !          4663:                                         * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
        !          4664:                                        /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
        !          4665:                                                 modality of the nth covariate of individual i. */
        !          4666:                                        if (ij > modmaxcovj)
        !          4667:                                                modmaxcovj=ij; 
        !          4668:                                        else if (ij < modmincovj) 
        !          4669:                                                modmincovj=ij; 
        !          4670:                                        if ((ij < -1) && (ij > NCOVMAX)){
        !          4671:                                                printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
        !          4672:                                                exit(1);
        !          4673:                                        }else
        !          4674:                                                Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
        !          4675:                                        /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
        !          4676:                                        /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
        !          4677:                                        /* getting the maximum value of the modality of the covariate
        !          4678:                                                 (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
        !          4679:                                                 female ies 1, then modmaxcovj=1.
        !          4680:                                        */
        !          4681:                                } /* end for loop on individuals i */
        !          4682:                                printf(" Minimal and maximal values of %d th covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
        !          4683:                                fprintf(ficlog," Minimal and maximal values of %d th covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
        !          4684:                                cptcode=modmaxcovj;
        !          4685:                                /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
        !          4686:                                /*for (i=0; i<=cptcode; i++) {*/
        !          4687:                                for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
        !          4688:                                        printf("Frequencies of covariates %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
        !          4689:                                        fprintf(ficlog, "Frequencies of covariates %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
        !          4690:                                        if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
        !          4691:                                                if( j != -1){
        !          4692:                                                        ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
        !          4693:                                                                                                                                 covariate for which somebody answered excluding 
        !          4694:                                                                                                                                 undefined. Usually 2: 0 and 1. */
        !          4695:                                                }
        !          4696:                                                ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
        !          4697:                                                                                                                                                covariate for which somebody answered including 
        !          4698:                                                                                                                                                undefined. Usually 3: -1, 0 and 1. */
        !          4699:                                        }       /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
        !          4700:                                                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
        !          4701:                                } /* Ndum[-1] number of undefined modalities */
        !          4702:                        
        !          4703:                                /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
        !          4704:                                /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
        !          4705:                                /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
        !          4706:                                /* modmincovj=3; modmaxcovj = 7; */
        !          4707:                                /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
        !          4708:                                /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
        !          4709:                          /*             defining two dummy variables: variables V1_1 and V1_2.*/
        !          4710:              /* nbcode[Tvar[j]][ij]=k; */
        !          4711:              /* nbcode[Tvar[j]][1]=0; */
        !          4712:              /* nbcode[Tvar[j]][2]=1; */
        !          4713:              /* nbcode[Tvar[j]][3]=2; */
        !          4714:              /* To be continued (not working yet). */
        !          4715:              ij=0; /* ij is similar to i but can jump over null modalities */
        !          4716:                                for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
        !          4717:          if (Ndum[i] == 0) { /* If nobody responded to this modality k */
        !          4718:                  break;
        !          4719:                }
        !          4720:                                        ij++;
        !          4721:                                        nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
        !          4722:                                        cptcode = ij; /* New max modality for covar j */
        !          4723:                                } /* end of loop on modality i=-1 to 1 or more */
        !          4724:                                break;
1.227     brouard  4725:       case 1: /* Testing on varying covariate, could be simple and
                   4726:               * should look at waves or product of fixed *
                   4727:               * varying. No time to test -1, assuming 0 and 1 only */
1.231   ! brouard  4728:                                ij=0;
        !          4729:                                for(i=0; i<=1;i++){
        !          4730:                                        nbcode[Tvar[k]][++ij]=i;
        !          4731:                                }
        !          4732:                                break;
1.227     brouard  4733:       default:
1.231   ! brouard  4734:                                break;
1.227     brouard  4735:       } /* end switch */
                   4736:     } /* end dummy test */
1.225     brouard  4737:     
1.192     brouard  4738:     /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   4739:     /*         /\*recode from 0 *\/ */
                   4740:     /*                                      k is a modality. If we have model=V1+V1*sex  */
                   4741:     /*                                      then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   4742:     /*                                   But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   4743:     /*         } */
                   4744:     /*         /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   4745:     /*         if (ij > ncodemax[j]) { */
                   4746:     /*           printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   4747:     /*           fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   4748:     /*           break; */
                   4749:     /*         } */
                   4750:     /*   }  /\* end of loop on modality k *\/ */
1.137     brouard  4751:   } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   4752:   
1.225     brouard  4753:   for (k=-1; k< maxncov; k++) Ndum[k]=0; 
1.227     brouard  4754:   /* Look at fixed dummy (single or product) covariates to check empty modalities */
1.187     brouard  4755:   for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
1.225     brouard  4756:     /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
1.227     brouard  4757:     ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   4758:     Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   4759:     /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
1.225     brouard  4760:   } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   4761:   
                   4762:   ij=0;
1.227     brouard  4763:   /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   4764:   for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
1.225     brouard  4765:     /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
1.227     brouard  4766:     /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   4767:     if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   4768:       /* If product not in single variable we don't print results */
1.225     brouard  4769:       /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
1.230     brouard  4770:       ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   4771:       Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   4772:       Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
1.231   ! brouard  4773:       TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
1.227     brouard  4774:       if(Fixed[k]!=0)
                   4775:         anyvaryingduminmodel=1;
1.231   ! brouard  4776:                        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
        !          4777:                        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
        !          4778:                        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
        !          4779:                        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
        !          4780:                        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
        !          4781:                        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
1.227     brouard  4782:     } 
1.225     brouard  4783:   } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   4784:   /* ij--; */
                   4785:   /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   4786:   *cptcov=ij; /*Number of total real effective covariates: effective
1.231   ! brouard  4787:                                                         * because they can be excluded from the model and real
        !          4788:                                                         * if in the model but excluded because missing values, but how to get k from ij?*/
1.227     brouard  4789:   for(j=ij+1; j<= cptcovt; j++){
                   4790:     Tvaraff[j]=0;
                   4791:     Tmodelind[j]=0;
                   4792:   }
1.228     brouard  4793:   for(j=ntveff+1; j<= cptcovt; j++){
                   4794:     TmodelInvind[j]=0;
                   4795:   }
1.227     brouard  4796:   /* To be sorted */
                   4797:   ;
1.126     brouard  4798: }
                   4799: 
1.145     brouard  4800: 
1.126     brouard  4801: /*********** Health Expectancies ****************/
                   4802: 
1.127     brouard  4803: void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[] )
1.126     brouard  4804: 
                   4805: {
                   4806:   /* Health expectancies, no variances */
1.164     brouard  4807:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  4808:   int nhstepma, nstepma; /* Decreasing with age */
                   4809:   double age, agelim, hf;
                   4810:   double ***p3mat;
                   4811:   double eip;
                   4812: 
                   4813:   pstamp(ficreseij);
                   4814:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   4815:   fprintf(ficreseij,"# Age");
                   4816:   for(i=1; i<=nlstate;i++){
                   4817:     for(j=1; j<=nlstate;j++){
                   4818:       fprintf(ficreseij," e%1d%1d ",i,j);
                   4819:     }
                   4820:     fprintf(ficreseij," e%1d. ",i);
                   4821:   }
                   4822:   fprintf(ficreseij,"\n");
                   4823: 
                   4824:   
                   4825:   if(estepm < stepm){
                   4826:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   4827:   }
                   4828:   else  hstepm=estepm;   
                   4829:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   4830:    * This is mainly to measure the difference between two models: for example
                   4831:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   4832:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   4833:    * progression in between and thus overestimating or underestimating according
                   4834:    * to the curvature of the survival function. If, for the same date, we 
                   4835:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   4836:    * to compare the new estimate of Life expectancy with the same linear 
                   4837:    * hypothesis. A more precise result, taking into account a more precise
                   4838:    * curvature will be obtained if estepm is as small as stepm. */
                   4839: 
                   4840:   /* For example we decided to compute the life expectancy with the smallest unit */
                   4841:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   4842:      nhstepm is the number of hstepm from age to agelim 
                   4843:      nstepm is the number of stepm from age to agelin. 
                   4844:      Look at hpijx to understand the reason of that which relies in memory size
                   4845:      and note for a fixed period like estepm months */
                   4846:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   4847:      survival function given by stepm (the optimization length). Unfortunately it
                   4848:      means that if the survival funtion is printed only each two years of age and if
                   4849:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   4850:      results. So we changed our mind and took the option of the best precision.
                   4851:   */
                   4852:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   4853: 
                   4854:   agelim=AGESUP;
                   4855:   /* If stepm=6 months */
                   4856:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   4857:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   4858:     
                   4859: /* nhstepm age range expressed in number of stepm */
                   4860:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   4861:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   4862:   /* if (stepm >= YEARM) hstepm=1;*/
                   4863:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   4864:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   4865: 
                   4866:   for (age=bage; age<=fage; age ++){ 
                   4867:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   4868:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   4869:     /* if (stepm >= YEARM) hstepm=1;*/
                   4870:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   4871: 
                   4872:     /* If stepm=6 months */
                   4873:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   4874:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   4875:     
                   4876:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij);  
                   4877:     
                   4878:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   4879:     
                   4880:     printf("%d|",(int)age);fflush(stdout);
                   4881:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   4882:     
                   4883:     /* Computing expectancies */
                   4884:     for(i=1; i<=nlstate;i++)
                   4885:       for(j=1; j<=nlstate;j++)
                   4886:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   4887:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   4888:          
                   4889:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   4890: 
                   4891:        }
                   4892: 
                   4893:     fprintf(ficreseij,"%3.0f",age );
                   4894:     for(i=1; i<=nlstate;i++){
                   4895:       eip=0;
                   4896:       for(j=1; j<=nlstate;j++){
                   4897:        eip +=eij[i][j][(int)age];
                   4898:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   4899:       }
                   4900:       fprintf(ficreseij,"%9.4f", eip );
                   4901:     }
                   4902:     fprintf(ficreseij,"\n");
                   4903:     
                   4904:   }
                   4905:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   4906:   printf("\n");
                   4907:   fprintf(ficlog,"\n");
                   4908:   
                   4909: }
                   4910: 
1.127     brouard  4911: void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[] )
1.126     brouard  4912: 
                   4913: {
                   4914:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  4915:      to initial status i, ei. .
1.126     brouard  4916:   */
                   4917:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   4918:   int nhstepma, nstepma; /* Decreasing with age */
                   4919:   double age, agelim, hf;
                   4920:   double ***p3matp, ***p3matm, ***varhe;
                   4921:   double **dnewm,**doldm;
                   4922:   double *xp, *xm;
                   4923:   double **gp, **gm;
                   4924:   double ***gradg, ***trgradg;
                   4925:   int theta;
                   4926: 
                   4927:   double eip, vip;
                   4928: 
                   4929:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   4930:   xp=vector(1,npar);
                   4931:   xm=vector(1,npar);
                   4932:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   4933:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   4934:   
                   4935:   pstamp(ficresstdeij);
                   4936:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   4937:   fprintf(ficresstdeij,"# Age");
                   4938:   for(i=1; i<=nlstate;i++){
                   4939:     for(j=1; j<=nlstate;j++)
                   4940:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   4941:     fprintf(ficresstdeij," e%1d. ",i);
                   4942:   }
                   4943:   fprintf(ficresstdeij,"\n");
                   4944: 
                   4945:   pstamp(ficrescveij);
                   4946:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   4947:   fprintf(ficrescveij,"# Age");
                   4948:   for(i=1; i<=nlstate;i++)
                   4949:     for(j=1; j<=nlstate;j++){
                   4950:       cptj= (j-1)*nlstate+i;
                   4951:       for(i2=1; i2<=nlstate;i2++)
                   4952:        for(j2=1; j2<=nlstate;j2++){
                   4953:          cptj2= (j2-1)*nlstate+i2;
                   4954:          if(cptj2 <= cptj)
                   4955:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   4956:        }
                   4957:     }
                   4958:   fprintf(ficrescveij,"\n");
                   4959:   
                   4960:   if(estepm < stepm){
                   4961:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   4962:   }
                   4963:   else  hstepm=estepm;   
                   4964:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   4965:    * This is mainly to measure the difference between two models: for example
                   4966:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   4967:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   4968:    * progression in between and thus overestimating or underestimating according
                   4969:    * to the curvature of the survival function. If, for the same date, we 
                   4970:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   4971:    * to compare the new estimate of Life expectancy with the same linear 
                   4972:    * hypothesis. A more precise result, taking into account a more precise
                   4973:    * curvature will be obtained if estepm is as small as stepm. */
                   4974: 
                   4975:   /* For example we decided to compute the life expectancy with the smallest unit */
                   4976:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   4977:      nhstepm is the number of hstepm from age to agelim 
                   4978:      nstepm is the number of stepm from age to agelin. 
                   4979:      Look at hpijx to understand the reason of that which relies in memory size
                   4980:      and note for a fixed period like estepm months */
                   4981:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   4982:      survival function given by stepm (the optimization length). Unfortunately it
                   4983:      means that if the survival funtion is printed only each two years of age and if
                   4984:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   4985:      results. So we changed our mind and took the option of the best precision.
                   4986:   */
                   4987:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   4988: 
                   4989:   /* If stepm=6 months */
                   4990:   /* nhstepm age range expressed in number of stepm */
                   4991:   agelim=AGESUP;
                   4992:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   4993:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   4994:   /* if (stepm >= YEARM) hstepm=1;*/
                   4995:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   4996:   
                   4997:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   4998:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   4999:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5000:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5001:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5002:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5003: 
                   5004:   for (age=bage; age<=fage; age ++){ 
                   5005:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5006:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5007:     /* if (stepm >= YEARM) hstepm=1;*/
                   5008:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5009:                
1.126     brouard  5010:     /* If stepm=6 months */
                   5011:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5012:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5013:     
                   5014:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5015:                
1.126     brouard  5016:     /* Computing  Variances of health expectancies */
                   5017:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5018:        decrease memory allocation */
                   5019:     for(theta=1; theta <=npar; theta++){
                   5020:       for(i=1; i<=npar; i++){ 
1.222     brouard  5021:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5022:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5023:       }
                   5024:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij);  
                   5025:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij);  
1.218     brouard  5026:                        
1.126     brouard  5027:       for(j=1; j<= nlstate; j++){
1.222     brouard  5028:        for(i=1; i<=nlstate; i++){
                   5029:          for(h=0; h<=nhstepm-1; h++){
                   5030:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5031:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5032:          }
                   5033:        }
1.126     brouard  5034:       }
1.218     brouard  5035:                        
1.126     brouard  5036:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5037:        for(h=0; h<=nhstepm-1; h++){
                   5038:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5039:        }
1.126     brouard  5040:     }/* End theta */
                   5041:     
                   5042:     
                   5043:     for(h=0; h<=nhstepm-1; h++)
                   5044:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5045:        for(theta=1; theta <=npar; theta++)
                   5046:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5047:     
1.218     brouard  5048:                
1.222     brouard  5049:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5050:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5051:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5052:                
1.222     brouard  5053:     printf("%d|",(int)age);fflush(stdout);
                   5054:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5055:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5056:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5057:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5058:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5059:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5060:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5061:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5062:       }
                   5063:     }
1.218     brouard  5064:                
1.126     brouard  5065:     /* Computing expectancies */
                   5066:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij);  
                   5067:     for(i=1; i<=nlstate;i++)
                   5068:       for(j=1; j<=nlstate;j++)
1.222     brouard  5069:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5070:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5071:                                        
1.222     brouard  5072:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5073:                                        
1.222     brouard  5074:        }
1.218     brouard  5075:                
1.126     brouard  5076:     fprintf(ficresstdeij,"%3.0f",age );
                   5077:     for(i=1; i<=nlstate;i++){
                   5078:       eip=0.;
                   5079:       vip=0.;
                   5080:       for(j=1; j<=nlstate;j++){
1.222     brouard  5081:        eip += eij[i][j][(int)age];
                   5082:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5083:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5084:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5085:       }
                   5086:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5087:     }
                   5088:     fprintf(ficresstdeij,"\n");
1.218     brouard  5089:                
1.126     brouard  5090:     fprintf(ficrescveij,"%3.0f",age );
                   5091:     for(i=1; i<=nlstate;i++)
                   5092:       for(j=1; j<=nlstate;j++){
1.222     brouard  5093:        cptj= (j-1)*nlstate+i;
                   5094:        for(i2=1; i2<=nlstate;i2++)
                   5095:          for(j2=1; j2<=nlstate;j2++){
                   5096:            cptj2= (j2-1)*nlstate+i2;
                   5097:            if(cptj2 <= cptj)
                   5098:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5099:          }
1.126     brouard  5100:       }
                   5101:     fprintf(ficrescveij,"\n");
1.218     brouard  5102:                
1.126     brouard  5103:   }
                   5104:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5105:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5106:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5107:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5108:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5109:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5110:   printf("\n");
                   5111:   fprintf(ficlog,"\n");
1.218     brouard  5112:        
1.126     brouard  5113:   free_vector(xm,1,npar);
                   5114:   free_vector(xp,1,npar);
                   5115:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5116:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5117:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5118: }
1.218     brouard  5119:  
1.126     brouard  5120: /************ Variance ******************/
1.209     brouard  5121:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[])
1.218     brouard  5122:  {
                   5123:    /* Variance of health expectancies */
                   5124:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5125:    /* double **newm;*/
                   5126:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5127:   
                   5128:    /* int movingaverage(); */
                   5129:    double **dnewm,**doldm;
                   5130:    double **dnewmp,**doldmp;
                   5131:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5132:    int k;
                   5133:    double *xp;
                   5134:    double **gp, **gm;  /* for var eij */
                   5135:    double ***gradg, ***trgradg; /*for var eij */
                   5136:    double **gradgp, **trgradgp; /* for var p point j */
                   5137:    double *gpp, *gmp; /* for var p point j */
                   5138:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5139:    double ***p3mat;
                   5140:    double age,agelim, hf;
                   5141:    /* double ***mobaverage; */
                   5142:    int theta;
                   5143:    char digit[4];
                   5144:    char digitp[25];
                   5145: 
                   5146:    char fileresprobmorprev[FILENAMELENGTH];
                   5147: 
                   5148:    if(popbased==1){
                   5149:      if(mobilav!=0)
                   5150:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5151:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5152:    }
                   5153:    else 
                   5154:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5155: 
1.218     brouard  5156:    /* if (mobilav!=0) { */
                   5157:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5158:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5159:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5160:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5161:    /*   } */
                   5162:    /* } */
                   5163: 
                   5164:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5165:    sprintf(digit,"%-d",ij);
                   5166:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5167:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5168:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5169:    strcat(fileresprobmorprev,fileresu);
                   5170:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5171:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5172:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5173:    }
                   5174:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5175:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5176:    pstamp(ficresprobmorprev);
                   5177:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
                   5178:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5179:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5180:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5181:      for(i=1; i<=nlstate;i++)
                   5182:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5183:    }  
                   5184:    fprintf(ficresprobmorprev,"\n");
                   5185:   
                   5186:    fprintf(ficgp,"\n# Routine varevsij");
                   5187:    fprintf(ficgp,"\nunset title \n");
                   5188:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5189:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5190:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5191:    /*   } */
                   5192:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5193:    pstamp(ficresvij);
                   5194:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5195:    if(popbased==1)
                   5196:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5197:    else
                   5198:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5199:    fprintf(ficresvij,"# Age");
                   5200:    for(i=1; i<=nlstate;i++)
                   5201:      for(j=1; j<=nlstate;j++)
                   5202:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5203:    fprintf(ficresvij,"\n");
                   5204: 
                   5205:    xp=vector(1,npar);
                   5206:    dnewm=matrix(1,nlstate,1,npar);
                   5207:    doldm=matrix(1,nlstate,1,nlstate);
                   5208:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5209:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5210: 
                   5211:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5212:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5213:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5214:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5215:   
1.218     brouard  5216:    if(estepm < stepm){
                   5217:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5218:    }
                   5219:    else  hstepm=estepm;   
                   5220:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5221:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5222:       nhstepm is the number of hstepm from age to agelim 
                   5223:       nstepm is the number of stepm from age to agelim. 
                   5224:       Look at function hpijx to understand why because of memory size limitations, 
                   5225:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5226:       survival function given by stepm (the optimization length). Unfortunately it
                   5227:       means that if the survival funtion is printed every two years of age and if
                   5228:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5229:       results. So we changed our mind and took the option of the best precision.
                   5230:    */
                   5231:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5232:    agelim = AGESUP;
                   5233:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5234:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5235:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5236:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5237:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5238:      gp=matrix(0,nhstepm,1,nlstate);
                   5239:      gm=matrix(0,nhstepm,1,nlstate);
                   5240:                
                   5241:                
                   5242:      for(theta=1; theta <=npar; theta++){
                   5243:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5244:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5245:        }
                   5246:                        
                   5247:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij);
                   5248:                        
                   5249:        if (popbased==1) {
                   5250:         if(mobilav ==0){
                   5251:           for(i=1; i<=nlstate;i++)
                   5252:             prlim[i][i]=probs[(int)age][i][ij];
                   5253:         }else{ /* mobilav */ 
                   5254:           for(i=1; i<=nlstate;i++)
                   5255:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5256:         }
                   5257:        }
                   5258:                        
                   5259:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
                   5260:        for(j=1; j<= nlstate; j++){
                   5261:         for(h=0; h<=nhstepm; h++){
                   5262:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5263:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5264:         }
                   5265:        }
                   5266:        /* Next for computing probability of death (h=1 means
                   5267:          computed over hstepm matrices product = hstepm*stepm months) 
                   5268:          as a weighted average of prlim.
                   5269:        */
                   5270:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5271:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5272:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5273:        }    
                   5274:        /* end probability of death */
                   5275:                        
                   5276:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5277:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5278:                        
                   5279:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij);
                   5280:                        
                   5281:        if (popbased==1) {
                   5282:         if(mobilav ==0){
                   5283:           for(i=1; i<=nlstate;i++)
                   5284:             prlim[i][i]=probs[(int)age][i][ij];
                   5285:         }else{ /* mobilav */ 
                   5286:           for(i=1; i<=nlstate;i++)
                   5287:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5288:         }
                   5289:        }
                   5290:                        
                   5291:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);  
                   5292:                        
                   5293:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5294:         for(h=0; h<=nhstepm; h++){
                   5295:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5296:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5297:         }
                   5298:        }
                   5299:        /* This for computing probability of death (h=1 means
                   5300:          computed over hstepm matrices product = hstepm*stepm months) 
                   5301:          as a weighted average of prlim.
                   5302:        */
                   5303:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5304:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5305:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5306:        }    
                   5307:        /* end probability of death */
                   5308:                        
                   5309:        for(j=1; j<= nlstate; j++) /* vareij */
                   5310:         for(h=0; h<=nhstepm; h++){
                   5311:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5312:         }
                   5313:                        
                   5314:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5315:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5316:        }
                   5317:                        
                   5318:      } /* End theta */
                   5319:                
                   5320:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5321:                
                   5322:      for(h=0; h<=nhstepm; h++) /* veij */
                   5323:        for(j=1; j<=nlstate;j++)
                   5324:         for(theta=1; theta <=npar; theta++)
                   5325:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5326:                
                   5327:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5328:        for(theta=1; theta <=npar; theta++)
                   5329:         trgradgp[j][theta]=gradgp[theta][j];
                   5330:                
                   5331:                
                   5332:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5333:      for(i=1;i<=nlstate;i++)
                   5334:        for(j=1;j<=nlstate;j++)
                   5335:         vareij[i][j][(int)age] =0.;
                   5336:                
                   5337:      for(h=0;h<=nhstepm;h++){
                   5338:        for(k=0;k<=nhstepm;k++){
                   5339:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5340:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5341:         for(i=1;i<=nlstate;i++)
                   5342:           for(j=1;j<=nlstate;j++)
                   5343:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5344:        }
                   5345:      }
                   5346:                
                   5347:      /* pptj */
                   5348:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5349:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5350:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5351:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5352:         varppt[j][i]=doldmp[j][i];
                   5353:      /* end ppptj */
                   5354:      /*  x centered again */
                   5355:                
                   5356:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij);
                   5357:                
                   5358:      if (popbased==1) {
                   5359:        if(mobilav ==0){
                   5360:         for(i=1; i<=nlstate;i++)
                   5361:           prlim[i][i]=probs[(int)age][i][ij];
                   5362:        }else{ /* mobilav */ 
                   5363:         for(i=1; i<=nlstate;i++)
                   5364:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   5365:        }
                   5366:      }
                   5367:                
                   5368:      /* This for computing probability of death (h=1 means
                   5369:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   5370:        as a weighted average of prlim.
                   5371:      */
                   5372:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij);  
                   5373:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5374:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   5375:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   5376:      }    
                   5377:      /* end probability of death */
                   5378:                
                   5379:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   5380:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5381:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   5382:        for(i=1; i<=nlstate;i++){
                   5383:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   5384:        }
                   5385:      } 
                   5386:      fprintf(ficresprobmorprev,"\n");
                   5387:                
                   5388:      fprintf(ficresvij,"%.0f ",age );
                   5389:      for(i=1; i<=nlstate;i++)
                   5390:        for(j=1; j<=nlstate;j++){
                   5391:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   5392:        }
                   5393:      fprintf(ficresvij,"\n");
                   5394:      free_matrix(gp,0,nhstepm,1,nlstate);
                   5395:      free_matrix(gm,0,nhstepm,1,nlstate);
                   5396:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   5397:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   5398:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5399:    } /* End age */
                   5400:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   5401:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   5402:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   5403:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   5404:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   5405:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   5406:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   5407:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   5408:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5409:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   5410:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5411:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5412:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   5413:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   5414:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   5415:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   5416:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5417:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  5418:     */
1.218     brouard  5419:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   5420:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  5421: 
1.218     brouard  5422:    free_vector(xp,1,npar);
                   5423:    free_matrix(doldm,1,nlstate,1,nlstate);
                   5424:    free_matrix(dnewm,1,nlstate,1,npar);
                   5425:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5426:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   5427:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5428:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5429:    fclose(ficresprobmorprev);
                   5430:    fflush(ficgp);
                   5431:    fflush(fichtm); 
                   5432:  }  /* end varevsij */
1.126     brouard  5433: 
                   5434: /************ Variance of prevlim ******************/
1.209     brouard  5435:  void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[])
1.126     brouard  5436: {
1.205     brouard  5437:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  5438:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  5439: 
1.126     brouard  5440:   double **dnewm,**doldm;
                   5441:   int i, j, nhstepm, hstepm;
                   5442:   double *xp;
                   5443:   double *gp, *gm;
                   5444:   double **gradg, **trgradg;
1.208     brouard  5445:   double **mgm, **mgp;
1.126     brouard  5446:   double age,agelim;
                   5447:   int theta;
                   5448:   
                   5449:   pstamp(ficresvpl);
                   5450:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
                   5451:   fprintf(ficresvpl,"# Age");
                   5452:   for(i=1; i<=nlstate;i++)
                   5453:       fprintf(ficresvpl," %1d-%1d",i,i);
                   5454:   fprintf(ficresvpl,"\n");
                   5455: 
                   5456:   xp=vector(1,npar);
                   5457:   dnewm=matrix(1,nlstate,1,npar);
                   5458:   doldm=matrix(1,nlstate,1,nlstate);
                   5459:   
                   5460:   hstepm=1*YEARM; /* Every year of age */
                   5461:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   5462:   agelim = AGESUP;
                   5463:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5464:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5465:     if (stepm >= YEARM) hstepm=1;
                   5466:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   5467:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  5468:     mgp=matrix(1,npar,1,nlstate);
                   5469:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  5470:     gp=vector(1,nlstate);
                   5471:     gm=vector(1,nlstate);
                   5472: 
                   5473:     for(theta=1; theta <=npar; theta++){
                   5474:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   5475:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5476:       }
1.209     brouard  5477:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
                   5478:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij);
                   5479:       else
                   5480:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij);
1.208     brouard  5481:       for(i=1;i<=nlstate;i++){
1.126     brouard  5482:        gp[i] = prlim[i][i];
1.208     brouard  5483:        mgp[theta][i] = prlim[i][i];
                   5484:       }
1.126     brouard  5485:       for(i=1; i<=npar; i++) /* Computes gradient */
                   5486:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  5487:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
                   5488:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij);
                   5489:       else
                   5490:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij);
1.208     brouard  5491:       for(i=1;i<=nlstate;i++){
1.126     brouard  5492:        gm[i] = prlim[i][i];
1.208     brouard  5493:        mgm[theta][i] = prlim[i][i];
                   5494:       }
1.126     brouard  5495:       for(i=1;i<=nlstate;i++)
                   5496:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  5497:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  5498:     } /* End theta */
                   5499: 
                   5500:     trgradg =matrix(1,nlstate,1,npar);
                   5501: 
                   5502:     for(j=1; j<=nlstate;j++)
                   5503:       for(theta=1; theta <=npar; theta++)
                   5504:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  5505:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5506:     /*   printf("\nmgm mgp %d ",(int)age); */
                   5507:     /*   for(j=1; j<=nlstate;j++){ */
                   5508:     /*         printf(" %d ",j); */
                   5509:     /*         for(theta=1; theta <=npar; theta++) */
                   5510:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   5511:     /*         printf("\n "); */
                   5512:     /*   } */
                   5513:     /* } */
                   5514:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5515:     /*   printf("\n gradg %d ",(int)age); */
                   5516:     /*   for(j=1; j<=nlstate;j++){ */
                   5517:     /*         printf("%d ",j); */
                   5518:     /*         for(theta=1; theta <=npar; theta++) */
                   5519:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   5520:     /*         printf("\n "); */
                   5521:     /*   } */
                   5522:     /* } */
1.126     brouard  5523: 
                   5524:     for(i=1;i<=nlstate;i++)
                   5525:       varpl[i][(int)age] =0.;
1.209     brouard  5526:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.205     brouard  5527:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   5528:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
                   5529:     }else{
1.126     brouard  5530:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   5531:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  5532:     }
1.126     brouard  5533:     for(i=1;i<=nlstate;i++)
                   5534:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   5535: 
                   5536:     fprintf(ficresvpl,"%.0f ",age );
                   5537:     for(i=1; i<=nlstate;i++)
                   5538:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   5539:     fprintf(ficresvpl,"\n");
                   5540:     free_vector(gp,1,nlstate);
                   5541:     free_vector(gm,1,nlstate);
1.208     brouard  5542:     free_matrix(mgm,1,npar,1,nlstate);
                   5543:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  5544:     free_matrix(gradg,1,npar,1,nlstate);
                   5545:     free_matrix(trgradg,1,nlstate,1,npar);
                   5546:   } /* End age */
                   5547: 
                   5548:   free_vector(xp,1,npar);
                   5549:   free_matrix(doldm,1,nlstate,1,npar);
                   5550:   free_matrix(dnewm,1,nlstate,1,nlstate);
                   5551: 
                   5552: }
                   5553: 
                   5554: /************ Variance of one-step probabilities  ******************/
                   5555: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  5556:  {
                   5557:    int i, j=0,  k1, l1, tj;
                   5558:    int k2, l2, j1,  z1;
                   5559:    int k=0, l;
                   5560:    int first=1, first1, first2;
                   5561:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   5562:    double **dnewm,**doldm;
                   5563:    double *xp;
                   5564:    double *gp, *gm;
                   5565:    double **gradg, **trgradg;
                   5566:    double **mu;
                   5567:    double age, cov[NCOVMAX+1];
                   5568:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   5569:    int theta;
                   5570:    char fileresprob[FILENAMELENGTH];
                   5571:    char fileresprobcov[FILENAMELENGTH];
                   5572:    char fileresprobcor[FILENAMELENGTH];
                   5573:    double ***varpij;
                   5574: 
                   5575:    strcpy(fileresprob,"PROB_"); 
                   5576:    strcat(fileresprob,fileres);
                   5577:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   5578:      printf("Problem with resultfile: %s\n", fileresprob);
                   5579:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   5580:    }
                   5581:    strcpy(fileresprobcov,"PROBCOV_"); 
                   5582:    strcat(fileresprobcov,fileresu);
                   5583:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   5584:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   5585:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   5586:    }
                   5587:    strcpy(fileresprobcor,"PROBCOR_"); 
                   5588:    strcat(fileresprobcor,fileresu);
                   5589:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   5590:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   5591:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   5592:    }
                   5593:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   5594:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   5595:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   5596:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   5597:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   5598:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   5599:    pstamp(ficresprob);
                   5600:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   5601:    fprintf(ficresprob,"# Age");
                   5602:    pstamp(ficresprobcov);
                   5603:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   5604:    fprintf(ficresprobcov,"# Age");
                   5605:    pstamp(ficresprobcor);
                   5606:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   5607:    fprintf(ficresprobcor,"# Age");
1.126     brouard  5608: 
                   5609: 
1.222     brouard  5610:    for(i=1; i<=nlstate;i++)
                   5611:      for(j=1; j<=(nlstate+ndeath);j++){
                   5612:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   5613:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   5614:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   5615:      }  
                   5616:    /* fprintf(ficresprob,"\n");
                   5617:       fprintf(ficresprobcov,"\n");
                   5618:       fprintf(ficresprobcor,"\n");
                   5619:    */
                   5620:    xp=vector(1,npar);
                   5621:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   5622:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   5623:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   5624:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   5625:    first=1;
                   5626:    fprintf(ficgp,"\n# Routine varprob");
                   5627:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   5628:    fprintf(fichtm,"\n");
                   5629: 
                   5630:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.</li>\n",optionfilehtmcov);
                   5631:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   5632:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  5633: and drawn. It helps understanding how is the covariance between two incidences.\
                   5634:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  5635:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  5636: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   5637: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   5638: standard deviations wide on each axis. <br>\
                   5639:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   5640:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   5641: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   5642: 
1.222     brouard  5643:    cov[1]=1;
                   5644:    /* tj=cptcoveff; */
1.225     brouard  5645:    tj = (int) pow(2,cptcoveff);
1.222     brouard  5646:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   5647:    j1=0;
1.224     brouard  5648:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  5649:      if  (cptcovn>0) {
                   5650:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  5651:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5652:        fprintf(ficresprob, "**********\n#\n");
                   5653:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  5654:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5655:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  5656:                        
1.222     brouard  5657:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  5658:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5659:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  5660:                        
                   5661:                        
1.222     brouard  5662:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  5663:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5664:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  5665:                        
1.222     brouard  5666:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  5667:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5668:        fprintf(ficresprobcor, "**********\n#");    
                   5669:        if(invalidvarcomb[j1]){
                   5670:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   5671:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   5672:         continue;
                   5673:        }
                   5674:      }
                   5675:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   5676:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   5677:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   5678:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   5679:      for (age=bage; age<=fage; age ++){ 
                   5680:        cov[2]=age;
                   5681:        if(nagesqr==1)
                   5682:         cov[3]= age*age;
                   5683:        for (k=1; k<=cptcovn;k++) {
                   5684:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   5685:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   5686:                                                                    * 1  1 1 1 1
                   5687:                                                                    * 2  2 1 1 1
                   5688:                                                                    * 3  1 2 1 1
                   5689:                                                                    */
                   5690:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   5691:        }
                   5692:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   5693:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   5694:        for (k=1; k<=cptcovprod;k++)
                   5695:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  5696:                        
                   5697:                        
1.222     brouard  5698:        for(theta=1; theta <=npar; theta++){
                   5699:         for(i=1; i<=npar; i++)
                   5700:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  5701:                                
1.222     brouard  5702:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  5703:                                
1.222     brouard  5704:         k=0;
                   5705:         for(i=1; i<= (nlstate); i++){
                   5706:           for(j=1; j<=(nlstate+ndeath);j++){
                   5707:             k=k+1;
                   5708:             gp[k]=pmmij[i][j];
                   5709:           }
                   5710:         }
1.220     brouard  5711:                                
1.222     brouard  5712:         for(i=1; i<=npar; i++)
                   5713:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  5714:                                
1.222     brouard  5715:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   5716:         k=0;
                   5717:         for(i=1; i<=(nlstate); i++){
                   5718:           for(j=1; j<=(nlstate+ndeath);j++){
                   5719:             k=k+1;
                   5720:             gm[k]=pmmij[i][j];
                   5721:           }
                   5722:         }
1.220     brouard  5723:                                
1.222     brouard  5724:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   5725:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   5726:        }
1.126     brouard  5727: 
1.222     brouard  5728:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   5729:         for(theta=1; theta <=npar; theta++)
                   5730:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  5731:                        
1.222     brouard  5732:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   5733:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  5734:                        
1.222     brouard  5735:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  5736:                        
1.222     brouard  5737:        k=0;
                   5738:        for(i=1; i<=(nlstate); i++){
                   5739:         for(j=1; j<=(nlstate+ndeath);j++){
                   5740:           k=k+1;
                   5741:           mu[k][(int) age]=pmmij[i][j];
                   5742:         }
                   5743:        }
                   5744:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   5745:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   5746:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  5747:                        
1.222     brouard  5748:        /*printf("\n%d ",(int)age);
                   5749:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   5750:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   5751:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   5752:         }*/
1.220     brouard  5753:                        
1.222     brouard  5754:        fprintf(ficresprob,"\n%d ",(int)age);
                   5755:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   5756:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  5757:                        
1.222     brouard  5758:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   5759:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   5760:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   5761:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   5762:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   5763:        }
                   5764:        i=0;
                   5765:        for (k=1; k<=(nlstate);k++){
                   5766:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   5767:           i++;
                   5768:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   5769:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   5770:           for (j=1; j<=i;j++){
                   5771:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   5772:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   5773:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   5774:           }
                   5775:         }
                   5776:        }/* end of loop for state */
                   5777:      } /* end of loop for age */
                   5778:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   5779:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   5780:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   5781:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   5782:     
                   5783:      /* Confidence intervalle of pij  */
                   5784:      /*
                   5785:        fprintf(ficgp,"\nunset parametric;unset label");
                   5786:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   5787:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   5788:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   5789:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   5790:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   5791:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   5792:      */
                   5793:                
                   5794:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   5795:      first1=1;first2=2;
                   5796:      for (k2=1; k2<=(nlstate);k2++){
                   5797:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   5798:         if(l2==k2) continue;
                   5799:         j=(k2-1)*(nlstate+ndeath)+l2;
                   5800:         for (k1=1; k1<=(nlstate);k1++){
                   5801:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   5802:             if(l1==k1) continue;
                   5803:             i=(k1-1)*(nlstate+ndeath)+l1;
                   5804:             if(i<=j) continue;
                   5805:             for (age=bage; age<=fage; age ++){ 
                   5806:               if ((int)age %5==0){
                   5807:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   5808:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   5809:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   5810:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   5811:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   5812:                 c12=cv12/sqrt(v1*v2);
                   5813:                 /* Computing eigen value of matrix of covariance */
                   5814:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   5815:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   5816:                 if ((lc2 <0) || (lc1 <0) ){
                   5817:                   if(first2==1){
                   5818:                     first1=0;
                   5819:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   5820:                   }
                   5821:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   5822:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   5823:                   /* lc2=fabs(lc2); */
                   5824:                 }
1.220     brouard  5825:                                                                
1.222     brouard  5826:                 /* Eigen vectors */
                   5827:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   5828:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   5829:                 v21=(lc1-v1)/cv12*v11;
                   5830:                 v12=-v21;
                   5831:                 v22=v11;
                   5832:                 tnalp=v21/v11;
                   5833:                 if(first1==1){
                   5834:                   first1=0;
                   5835:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   5836:                 }
                   5837:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   5838:                 /*printf(fignu*/
                   5839:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   5840:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   5841:                 if(first==1){
                   5842:                   first=0;
                   5843:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   5844:                   fprintf(ficgp,"\nset parametric;unset label");
                   5845:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   5846:                   fprintf(ficgp,"\nset ter svg size 640, 480");
                   5847:                   fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  5848:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  5849: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  5850:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   5851:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   5852:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   5853:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   5854:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   5855:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   5856:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   5857:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
                   5858:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                                                         \
                   5859:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   5860:                 }else{
                   5861:                   first=0;
                   5862:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   5863:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   5864:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   5865:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
                   5866:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                 \
                   5867:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   5868:                 }/* if first */
                   5869:               } /* age mod 5 */
                   5870:             } /* end loop age */
                   5871:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   5872:             first=1;
                   5873:           } /*l12 */
                   5874:         } /* k12 */
                   5875:        } /*l1 */
                   5876:      }/* k1 */
                   5877:    }  /* loop on combination of covariates j1 */
                   5878:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   5879:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   5880:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   5881:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   5882:    free_vector(xp,1,npar);
                   5883:    fclose(ficresprob);
                   5884:    fclose(ficresprobcov);
                   5885:    fclose(ficresprobcor);
                   5886:    fflush(ficgp);
                   5887:    fflush(fichtmcov);
                   5888:  }
1.126     brouard  5889: 
                   5890: 
                   5891: /******************* Printing html file ***********/
1.201     brouard  5892: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  5893:                  int lastpass, int stepm, int weightopt, char model[],\
                   5894:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.217     brouard  5895:                  int popforecast, int prevfcast, int backcast, int estepm , \
1.213     brouard  5896:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   5897:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.126     brouard  5898:   int jj1, k1, i1, cpt;
                   5899: 
                   5900:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   5901:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   5902: </ul>");
1.214     brouard  5903:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   5904:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   5905:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   5906:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  5907:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   5908:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  5909:    fprintf(fichtm,"\
                   5910:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  5911:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  5912:    fprintf(fichtm,"\
1.217     brouard  5913:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   5914:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   5915:    fprintf(fichtm,"\
1.126     brouard  5916:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  5917:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  5918:    fprintf(fichtm,"\
1.217     brouard  5919:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   5920:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   5921:    fprintf(fichtm,"\
1.211     brouard  5922:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  5923:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  5924:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  5925:    if(prevfcast==1){
                   5926:      fprintf(fichtm,"\
                   5927:  - Prevalence projections by age and states:                           \
1.201     brouard  5928:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  5929:    }
1.126     brouard  5930: 
1.222     brouard  5931:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
1.126     brouard  5932: 
1.225     brouard  5933:    m=pow(2,cptcoveff);
1.222     brouard  5934:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  5935: 
1.222     brouard  5936:    jj1=0;
                   5937:    for(k1=1; k1<=m;k1++){
1.220     brouard  5938: 
1.222     brouard  5939:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   5940:      jj1++;
                   5941:      if (cptcovn > 0) {
                   5942:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  5943:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.222     brouard  5944:         fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);
                   5945:         printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout);
                   5946:        }
1.230     brouard  5947:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  5948:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   5949:        if(invalidvarcomb[k1]){
                   5950:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   5951:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   5952:         continue;
                   5953:        }
                   5954:      }
                   5955:      /* aij, bij */
                   5956:      fprintf(fichtm,"<br>- Logit model (yours is: 1+age+%s), for example: logit(pij)=log(pij/pii)= aij+ bij age + V1 age + etc. as a function of age: <a href=\"%s_%d-1.svg\">%s_%d-1.svg</a><br> \
1.211     brouard  5957: <img src=\"%s_%d-1.svg\">",model,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1);
1.222     brouard  5958:      /* Pij */
                   5959:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2.svg\">%s_%d-2.svg</a><br> \
1.201     brouard  5960: <img src=\"%s_%d-2.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1);     
1.222     brouard  5961:      /* Quasi-incidences */
                   5962:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  5963:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  5964:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
                   5965: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3.svg\">%s_%d-3.svg</a><br> \
1.201     brouard  5966: <img src=\"%s_%d-3.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1); 
1.222     brouard  5967:      /* Survival functions (period) in state j */
                   5968:      for(cpt=1; cpt<=nlstate;cpt++){
                   5969:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> \
1.201     brouard  5970: <img src=\"%s_%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,jj1,subdirf2(optionfilefiname,"LIJ_"),cpt,jj1,subdirf2(optionfilefiname,"LIJ_"),cpt,jj1);
1.222     brouard  5971:      }
                   5972:      /* State specific survival functions (period) */
                   5973:      for(cpt=1; cpt<=nlstate;cpt++){
                   5974:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  5975:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.201     brouard  5976:  <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> <img src=\"%s_%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,jj1,subdirf2(optionfilefiname,"LIJT_"),cpt,jj1,subdirf2(optionfilefiname,"LIJT_"),cpt,jj1);
1.222     brouard  5977:      }
                   5978:      /* Period (stable) prevalence in each health state */
                   5979:      for(cpt=1; cpt<=nlstate;cpt++){
                   5980:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a><br> \
1.201     brouard  5981: <img src=\"%s_%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,jj1,subdirf2(optionfilefiname,"P_"),cpt,jj1,subdirf2(optionfilefiname,"P_"),cpt,jj1);
1.222     brouard  5982:      }
                   5983:      if(backcast==1){
                   5984:        /* Period (stable) back prevalence in each health state */
                   5985:        for(cpt=1; cpt<=nlstate;cpt++){
                   5986:         fprintf(fichtm,"<br>\n- Convergence to period (stable) back prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a><br> \
1.217     brouard  5987: <img src=\"%s_%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,jj1,subdirf2(optionfilefiname,"PB_"),cpt,jj1,subdirf2(optionfilefiname,"PB_"),cpt,jj1);
1.222     brouard  5988:        }
1.217     brouard  5989:      }
1.222     brouard  5990:      if(prevfcast==1){
                   5991:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   5992:        for(cpt=1; cpt<=nlstate;cpt++){
                   5993:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f) up to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> \
1.213     brouard  5994: <img src=\"%s_%d-%d.svg\">", dateprev1, dateprev2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,jj1,subdirf2(optionfilefiname,"PROJ_"),cpt,jj1,subdirf2(optionfilefiname,"PROJ_"),cpt,jj1);
1.222     brouard  5995:        }
                   5996:      }
1.220     brouard  5997:         
1.222     brouard  5998:      for(cpt=1; cpt<=nlstate;cpt++) {
                   5999:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d%d.svg\">%s_%d%d.svg</a> <br> \
1.201     brouard  6000: <img src=\"%s_%d%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,jj1,subdirf2(optionfilefiname,"EXP_"),cpt,jj1,subdirf2(optionfilefiname,"EXP_"),cpt,jj1);
1.222     brouard  6001:      }
                   6002:      /* } /\* end i1 *\/ */
                   6003:    }/* End k1 */
                   6004:    fprintf(fichtm,"</ul>");
1.126     brouard  6005: 
1.222     brouard  6006:    fprintf(fichtm,"\
1.126     brouard  6007: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6008:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6009:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6010: But because parameters are usually highly correlated (a higher incidence of disability \
                   6011: and a higher incidence of recovery can give very close observed transition) it might \
                   6012: be very useful to look not only at linear confidence intervals estimated from the \
                   6013: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6014: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6015: covariance matrix of the one-step probabilities. \
                   6016: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6017: 
1.222     brouard  6018:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6019:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6020:    fprintf(fichtm,"\
1.126     brouard  6021:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6022:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6023: 
1.222     brouard  6024:    fprintf(fichtm,"\
1.126     brouard  6025:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6026:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6027:    fprintf(fichtm,"\
1.126     brouard  6028:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6029:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6030:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6031:    fprintf(fichtm,"\
1.126     brouard  6032:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6033:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6034:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6035:    fprintf(fichtm,"\
1.128     brouard  6036:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6037:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6038:    fprintf(fichtm,"\
1.128     brouard  6039:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6040:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6041:    fprintf(fichtm,"\
1.126     brouard  6042:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6043:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6044: 
                   6045: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6046: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6047: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6048: /*     <br>",fileres,fileres,fileres,fileres); */
                   6049: /*  else  */
                   6050: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6051:    fflush(fichtm);
                   6052:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6053: 
1.225     brouard  6054:    m=pow(2,cptcoveff);
1.222     brouard  6055:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6056: 
1.222     brouard  6057:    jj1=0;
                   6058:    for(k1=1; k1<=m;k1++){
                   6059:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6060:      jj1++;
1.126     brouard  6061:      if (cptcovn > 0) {
                   6062:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6063:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.222     brouard  6064:         fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);
1.126     brouard  6065:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6066: 
1.222     brouard  6067:        if(invalidvarcomb[k1]){
                   6068:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6069:         continue;
                   6070:        }
1.126     brouard  6071:      }
                   6072:      for(cpt=1; cpt<=nlstate;cpt++) {
1.218     brouard  6073:        fprintf(fichtm,"\n<br>- Observed (cross-sectional) and period (incidence based) \
                   6074: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d.svg\"> %s_%d-%d.svg</a>\n <br>\
1.205     brouard  6075: <img src=\"%s_%d-%d.svg\">",cpt,subdirf2(optionfilefiname,"V_"),cpt,jj1,subdirf2(optionfilefiname,"V_"),cpt,jj1,subdirf2(optionfilefiname,"V_"),cpt,jj1);  
1.126     brouard  6076:      }
                   6077:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6078: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6079: true period expectancies (those weighted with period prevalences are also\
                   6080:  drawn in addition to the population based expectancies computed using\
1.218     brouard  6081:  observed and cahotic prevalences:  <a href=\"%s_%d.svg\">%s_%d.svg</a>\n<br>\
1.205     brouard  6082: <img src=\"%s_%d.svg\">",subdirf2(optionfilefiname,"E_"),jj1,subdirf2(optionfilefiname,"E_"),jj1,subdirf2(optionfilefiname,"E_"),jj1);
1.222     brouard  6083:      /* } /\* end i1 *\/ */
                   6084:    }/* End k1 */
                   6085:    fprintf(fichtm,"</ul>");
                   6086:    fflush(fichtm);
1.126     brouard  6087: }
                   6088: 
                   6089: /******************* Gnuplot file **************/
1.223     brouard  6090: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[]){
1.126     brouard  6091: 
                   6092:   char dirfileres[132],optfileres[132];
1.223     brouard  6093:   char gplotcondition[132];
1.164     brouard  6094:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,ij=0,l=0;
1.211     brouard  6095:   int lv=0, vlv=0, kl=0;
1.130     brouard  6096:   int ng=0;
1.201     brouard  6097:   int vpopbased;
1.223     brouard  6098:   int ioffset; /* variable offset for columns */
1.219     brouard  6099: 
1.126     brouard  6100: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6101: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6102: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6103: /*   } */
                   6104: 
                   6105:   /*#ifdef windows */
                   6106:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6107:   /*#endif */
1.225     brouard  6108:   m=pow(2,cptcoveff);
1.126     brouard  6109: 
1.202     brouard  6110:   /* Contribution to likelihood */
                   6111:   /* Plot the probability implied in the likelihood */
1.223     brouard  6112:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6113:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6114:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6115:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6116: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6117:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6118: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6119:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6120:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6121:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6122:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6123:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6124:   for (i=1; i<= nlstate ; i ++) {
                   6125:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6126:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6127:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6128:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6129:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6130:     }
                   6131:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6132:   }
                   6133:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6134:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6135:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6136:   fprintf(ficgp,"\nset out;unset log\n");
                   6137:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6138: 
1.126     brouard  6139:   strcpy(dirfileres,optionfilefiname);
                   6140:   strcpy(optfileres,"vpl");
1.223     brouard  6141:   /* 1eme*/
1.211     brouard  6142:   for (cpt=1; cpt<= nlstate ; cpt ++) { /* For each live state */
1.230     brouard  6143:     for (k1=1; k1<= m && selected(k1) ; k1 ++) { /* For each valid combination of covariate */
1.211     brouard  6144:       /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
                   6145:       fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files ");
1.225     brouard  6146:       for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6147:        lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
1.223     brouard  6148:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6149:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6150:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6151:        vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   6152:        /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
                   6153:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6154:       }
                   6155:       fprintf(ficgp,"\n#\n");
1.223     brouard  6156:       if(invalidvarcomb[k1]){
                   6157:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6158:        continue;
                   6159:       }
1.211     brouard  6160: 
1.223     brouard  6161:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1);
                   6162:       fprintf(ficgp,"\n#set out \"V_%s_%d-%d.svg\" \n",optionfilefiname,cpt,k1);
                   6163:       fprintf(ficgp,"set xlabel \"Age\" \n\
1.219     brouard  6164: set ylabel \"Probability\" \n  \
                   6165: set ter svg size 640, 480\n    \
1.201     brouard  6166: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:2 \"%%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1);
1.219     brouard  6167:                        
1.223     brouard  6168:       for (i=1; i<= nlstate ; i ++) {
                   6169:        if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6170:        else        fprintf(ficgp," %%*lf (%%*lf)");
                   6171:       }
                   6172:       fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2+1.96*$3) \"%%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1);
                   6173:       for (i=1; i<= nlstate ; i ++) {
                   6174:        if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6175:        else fprintf(ficgp," %%*lf (%%*lf)");
                   6176:       } 
                   6177:       fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2-1.96*$3) \"%%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1); 
                   6178:       for (i=1; i<= nlstate ; i ++) {
                   6179:        if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6180:        else fprintf(ficgp," %%*lf (%%*lf)");
                   6181:       }  
                   6182:       fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1));
                   6183:       if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   6184:        /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
                   6185:        fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1 */
1.225     brouard  6186:        if(cptcoveff ==0){
1.223     brouard  6187:          fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line ",  2+(cpt-1),  cpt );
                   6188:        }else{
                   6189:          kl=0;
1.225     brouard  6190:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   6191:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
1.223     brouard  6192:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6193:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6194:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6195:            vlv= nbcode[Tvaraff[k]][lv];
                   6196:            kl++;
                   6197:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6198:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6199:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6200:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
1.225     brouard  6201:            if(k==cptcoveff){
1.227     brouard  6202:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   6203:                      4+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.223     brouard  6204:            }else{
                   6205:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   6206:              kl++;
                   6207:            }
                   6208:          } /* end covariate */
                   6209:        } /* end if no covariate */
                   6210:       } /* end if backcast */
                   6211:       fprintf(ficgp,"\nset out \n");
1.201     brouard  6212:     } /* k1 */
                   6213:   } /* cpt */
1.126     brouard  6214:   /*2 eme*/
                   6215:   for (k1=1; k1<= m ; k1 ++) { 
1.220     brouard  6216: 
1.223     brouard  6217:     fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.225     brouard  6218:     for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6219:       lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6220:       /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6221:       /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6222:       /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6223:       vlv= nbcode[Tvaraff[k]][lv];
                   6224:       fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6225:     }
                   6226:     fprintf(ficgp,"\n#\n");
                   6227:     if(invalidvarcomb[k1]){
                   6228:       fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6229:       continue;
                   6230:     }
1.219     brouard  6231:                        
1.223     brouard  6232:     fprintf(ficgp,"\nset out \"%s_%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1);
                   6233:     for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
                   6234:       if(vpopbased==0)
                   6235:        fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
                   6236:       else
                   6237:        fprintf(ficgp,"\nreplot ");
                   6238:       for (i=1; i<= nlstate+1 ; i ++) {
                   6239:        k=2*i;
                   6240:        fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1, vpopbased);
                   6241:        for (j=1; j<= nlstate+1 ; j ++) {
                   6242:          if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6243:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6244:        }   
                   6245:        if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   6246:        else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
                   6247:        fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6248:        for (j=1; j<= nlstate+1 ; j ++) {
                   6249:          if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6250:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6251:        }   
                   6252:        fprintf(ficgp,"\" t\"\" w l lt 0,");
                   6253:        fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6254:        for (j=1; j<= nlstate+1 ; j ++) {
                   6255:          if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6256:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6257:        }   
                   6258:        if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   6259:        else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   6260:       } /* state */
                   6261:     } /* vpopbased */
                   6262:     fprintf(ficgp,"\nset out;set out \"%s_%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1); /* Buggy gnuplot */
1.201     brouard  6263:   } /* k1 */
1.219     brouard  6264:        
                   6265:        
1.126     brouard  6266:   /*3eme*/
                   6267:   for (k1=1; k1<= m ; k1 ++) { 
1.220     brouard  6268: 
1.126     brouard  6269:     for (cpt=1; cpt<= nlstate ; cpt ++) {
1.211     brouard  6270:       fprintf(ficgp,"\n# 3d: Life expectancy with EXP_ files:  cov=%d state=%d",k1, cpt);
1.225     brouard  6271:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6272:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6273:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6274:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6275:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6276:        vlv= nbcode[Tvaraff[k]][lv];
                   6277:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6278:       }
                   6279:       fprintf(ficgp,"\n#\n");
1.223     brouard  6280:       if(invalidvarcomb[k1]){
                   6281:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6282:        continue;
                   6283:       }
1.219     brouard  6284:                        
1.126     brouard  6285:       /*       k=2+nlstate*(2*cpt-2); */
                   6286:       k=2+(nlstate+1)*(cpt-1);
1.201     brouard  6287:       fprintf(ficgp,"\nset out \"%s_%d%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1);
1.199     brouard  6288:       fprintf(ficgp,"set ter svg size 640, 480\n\
1.201     brouard  6289: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),k1-1,k1-1,k,cpt);
1.126     brouard  6290:       /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
1.223     brouard  6291:        for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6292:        fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   6293:        fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6294:        for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6295:        fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  6296:                                
1.126     brouard  6297:       */
                   6298:       for (i=1; i< nlstate ; i ++) {
1.223     brouard  6299:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+i,cpt,i+1);
                   6300:        /*      fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  6301:                                
1.126     brouard  6302:       } 
1.201     brouard  6303:       fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+nlstate,cpt);
1.126     brouard  6304:     }
                   6305:   }
                   6306:   
1.223     brouard  6307:   /* 4eme */
1.201     brouard  6308:   /* Survival functions (period) from state i in state j by initial state i */
                   6309:   for (k1=1; k1<= m ; k1 ++) { /* For each multivariate if any */
1.220     brouard  6310: 
1.201     brouard  6311:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.211     brouard  6312:       fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
1.225     brouard  6313:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6314:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6315:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6316:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6317:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6318:        vlv= nbcode[Tvaraff[k]][lv];
                   6319:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6320:       }
                   6321:       fprintf(ficgp,"\n#\n");
1.223     brouard  6322:       if(invalidvarcomb[k1]){
                   6323:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6324:        continue;
                   6325:       }
1.220     brouard  6326:                        
1.201     brouard  6327:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1);
                   6328:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
1.220     brouard  6329: set ter svg size 640, 480\n                                                                                                                                                                                    \
                   6330: unset log y\n                                                                                                                                                                                                                                          \
1.201     brouard  6331: plot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6332:       k=3;
1.201     brouard  6333:       for (i=1; i<= nlstate ; i ++){
1.223     brouard  6334:        if(i==1){
                   6335:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6336:        }else{
                   6337:          fprintf(ficgp,", '' ");
                   6338:        }
                   6339:        l=(nlstate+ndeath)*(i-1)+1;
                   6340:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6341:        for (j=2; j<= nlstate+ndeath ; j ++)
                   6342:          fprintf(ficgp,"+$%d",k+l+j-1);
                   6343:        fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
1.201     brouard  6344:       } /* nlstate */
                   6345:       fprintf(ficgp,"\nset out\n");
                   6346:     } /* end cpt state*/ 
                   6347:   } /* end covariate */  
1.220     brouard  6348:        
                   6349: /* 5eme */
1.201     brouard  6350:   /* Survival functions (period) from state i in state j by final state j */
1.202     brouard  6351:   for (k1=1; k1<= m ; k1 ++) { /* For each covariate if any */
1.201     brouard  6352:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.223     brouard  6353:                        
1.201     brouard  6354:       fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
1.225     brouard  6355:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  6356:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6357:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6358:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6359:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6360:        vlv= nbcode[Tvaraff[k]][lv];
                   6361:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6362:       }
                   6363:       fprintf(ficgp,"\n#\n");
1.223     brouard  6364:       if(invalidvarcomb[k1]){
1.227     brouard  6365:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6366:        continue;
1.223     brouard  6367:       }
1.227     brouard  6368:       
1.201     brouard  6369:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1);
                   6370:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
1.227     brouard  6371: set ter svg size 640, 480\n                                            \
                   6372: unset log y\n                                                          \
1.201     brouard  6373: plot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6374:       k=3;
1.201     brouard  6375:       for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
1.227     brouard  6376:        if(j==1)
                   6377:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6378:        else
                   6379:          fprintf(ficgp,", '' ");
                   6380:        l=(nlstate+ndeath)*(cpt-1) +j;
                   6381:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   6382:        /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   6383:        /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   6384:        fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
1.201     brouard  6385:       } /* nlstate */
                   6386:       fprintf(ficgp,", '' ");
                   6387:       fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   6388:       for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
1.227     brouard  6389:        l=(nlstate+ndeath)*(cpt-1) +j;
                   6390:        if(j < nlstate)
                   6391:          fprintf(ficgp,"$%d +",k+l);
                   6392:        else
                   6393:          fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
1.201     brouard  6394:       }
                   6395:       fprintf(ficgp,"\nset out\n");
                   6396:     } /* end cpt state*/ 
                   6397:   } /* end covariate */  
1.227     brouard  6398:   
1.220     brouard  6399: /* 6eme */
1.202     brouard  6400:   /* CV preval stable (period) for each covariate */
1.211     brouard  6401:   for (k1=1; k1<= m ; k1 ++) { /* For each covariate combination (1 to m=2**k), if any covariate is present */
1.153     brouard  6402:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6403:       
1.211     brouard  6404:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  6405:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  6406:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6407:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6408:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6409:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6410:        vlv= nbcode[Tvaraff[k]][lv];
                   6411:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6412:       }
                   6413:       fprintf(ficgp,"\n#\n");
1.223     brouard  6414:       if(invalidvarcomb[k1]){
1.227     brouard  6415:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6416:        continue;
1.223     brouard  6417:       }
1.227     brouard  6418:       
1.201     brouard  6419:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1);
1.126     brouard  6420:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.227     brouard  6421: set ter svg size 640, 480\n                                            \
                   6422: unset log y\n                                                          \
1.153     brouard  6423: plot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6424:       k=3; /* Offset */
1.153     brouard  6425:       for (i=1; i<= nlstate ; i ++){
1.227     brouard  6426:        if(i==1)
                   6427:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6428:        else
                   6429:          fprintf(ficgp,", '' ");
                   6430:        l=(nlstate+ndeath)*(i-1)+1;
                   6431:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6432:        for (j=2; j<= nlstate ; j ++)
                   6433:          fprintf(ficgp,"+$%d",k+l+j-1);
                   6434:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  6435:       } /* nlstate */
1.201     brouard  6436:       fprintf(ficgp,"\nset out\n");
1.153     brouard  6437:     } /* end cpt state*/ 
                   6438:   } /* end covariate */  
1.227     brouard  6439:   
                   6440:   
1.220     brouard  6441: /* 7eme */
1.218     brouard  6442:   if(backcast == 1){
1.217     brouard  6443:     /* CV back preval stable (period) for each covariate */
1.218     brouard  6444:     for (k1=1; k1<= m ; k1 ++) { /* For each covariate combination (1 to m=2**k), if any covariate is present */
                   6445:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6446:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
                   6447:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6448:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6449:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6450:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  6451:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  6452:          vlv= nbcode[Tvaraff[k]][lv];
                   6453:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6454:        }
                   6455:        fprintf(ficgp,"\n#\n");
                   6456:        if(invalidvarcomb[k1]){
                   6457:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6458:          continue;
                   6459:        }
                   6460:        
                   6461:        fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1);
                   6462:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
                   6463: set ter svg size 640, 480\n                                            \
                   6464: unset log y\n                                                          \
1.218     brouard  6465: plot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  6466:        k=3; /* Offset */
                   6467:        for (i=1; i<= nlstate ; i ++){
                   6468:          if(i==1)
                   6469:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   6470:          else
                   6471:            fprintf(ficgp,", '' ");
                   6472:          /* l=(nlstate+ndeath)*(i-1)+1; */
                   6473:          l=(nlstate+ndeath)*(cpt-1)+1;
                   6474:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   6475:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
                   6476:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+(cpt-1)+i-1); /* a vérifier */
                   6477:          /* for (j=2; j<= nlstate ; j ++) */
                   6478:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   6479:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
                   6480:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",i,cpt);
                   6481:        } /* nlstate */
                   6482:        fprintf(ficgp,"\nset out\n");
1.218     brouard  6483:       } /* end cpt state*/ 
                   6484:     } /* end covariate */  
                   6485:   } /* End if backcast */
                   6486:   
1.223     brouard  6487:   /* 8eme */
1.218     brouard  6488:   if(prevfcast==1){
                   6489:     /* Projection from cross-sectional to stable (period) for each covariate */
                   6490:     
                   6491:     for (k1=1; k1<= m ; k1 ++) { /* For each covariate combination (1 to m=2**k), if any covariate is present */
1.211     brouard  6492:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6493:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   6494:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   6495:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6496:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6497:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6498:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6499:          vlv= nbcode[Tvaraff[k]][lv];
                   6500:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6501:        }
                   6502:        fprintf(ficgp,"\n#\n");
                   6503:        if(invalidvarcomb[k1]){
                   6504:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6505:          continue;
                   6506:        }
                   6507:        
                   6508:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
                   6509:        fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1);
                   6510:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   6511: set ter svg size 640, 480\n                                            \
                   6512: unset log y\n                                                          \
1.219     brouard  6513: plot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  6514:        for (i=1; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   6515:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6516:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   6517:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6518:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   6519:          if(i==1){
                   6520:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   6521:          }else{
                   6522:            fprintf(ficgp,",\\\n '' ");
                   6523:          }
                   6524:          if(cptcoveff ==0){ /* No covariate */
                   6525:            ioffset=2; /* Age is in 2 */
                   6526:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   6527:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   6528:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   6529:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   6530:            fprintf(ficgp," u %d:(", ioffset); 
                   6531:            if(i==nlstate+1)
                   6532:              fprintf(ficgp," $%d/(1.-$%d)) t 'pw.%d' with line ",      \
                   6533:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   6534:            else
                   6535:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   6536:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   6537:          }else{ /* more than 2 covariates */
                   6538:            if(cptcoveff ==1){
                   6539:              ioffset=4; /* Age is in 4 */
                   6540:            }else{
                   6541:              ioffset=6; /* Age is in 6 */
                   6542:              /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6543:              /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   6544:            }   
                   6545:            fprintf(ficgp," u %d:(",ioffset); 
                   6546:            kl=0;
                   6547:            strcpy(gplotcondition,"(");
                   6548:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   6549:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   6550:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6551:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6552:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6553:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   6554:              kl++;
                   6555:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   6556:              kl++;
                   6557:              if(k <cptcoveff && cptcoveff>1)
                   6558:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   6559:            }
                   6560:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   6561:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6562:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6563:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6564:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6565:            if(i==nlstate+1){
                   6566:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p.%d' with line ", gplotcondition, \
                   6567:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   6568:            }else{
                   6569:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   6570:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   6571:            }
                   6572:          } /* end if covariate */
                   6573:        } /* nlstate */
                   6574:        fprintf(ficgp,"\nset out\n");
1.223     brouard  6575:       } /* end cpt state*/
                   6576:     } /* end covariate */
                   6577:   } /* End if prevfcast */
1.227     brouard  6578:   
                   6579:   
1.223     brouard  6580:   /* proba elementaires */
                   6581:   fprintf(ficgp,"\n##############\n#MLE estimated parameters\n#############\n");
1.126     brouard  6582:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  6583:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  6584:     for(k=1; k <=(nlstate+ndeath); k++){
                   6585:       if (k != i) {
1.227     brouard  6586:        fprintf(ficgp,"#   current state %d\n",k);
                   6587:        for(j=1; j <=ncovmodel; j++){
                   6588:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   6589:          jk++; 
                   6590:        }
                   6591:        fprintf(ficgp,"\n");
1.126     brouard  6592:       }
                   6593:     }
1.223     brouard  6594:   }
1.187     brouard  6595:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  6596:   
1.145     brouard  6597:   /*goto avoid;*/
1.200     brouard  6598:   fprintf(ficgp,"\n##############\n#Graphics of probabilities or incidences\n#############\n");
1.187     brouard  6599:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   6600:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   6601:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   6602:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   6603:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   6604:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   6605:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   6606:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   6607:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   6608:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   6609:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   6610:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   6611:   fprintf(ficgp,"#\n");
1.223     brouard  6612:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
                   6613:     fprintf(ficgp,"# ng=%d\n",ng);
1.225     brouard  6614:     fprintf(ficgp,"#   jk=1 to 2^%d=%d\n",cptcoveff,m);
1.223     brouard  6615:     for(jk=1; jk <=m; jk++) {
                   6616:       fprintf(ficgp,"#    jk=%d\n",jk);
                   6617:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng);
                   6618:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   6619:       if (ng==1){
                   6620:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   6621:        fprintf(ficgp,"\nunset log y");
                   6622:       }else if (ng==2){
                   6623:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   6624:        fprintf(ficgp,"\nset log y");
                   6625:       }else if (ng==3){
                   6626:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   6627:        fprintf(ficgp,"\nset log y");
                   6628:       }else
                   6629:        fprintf(ficgp,"\nunset title ");
                   6630:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   6631:       i=1;
                   6632:       for(k2=1; k2<=nlstate; k2++) {
                   6633:        k3=i;
                   6634:        for(k=1; k<=(nlstate+ndeath); k++) {
                   6635:          if (k != k2){
                   6636:            switch( ng) {
                   6637:            case 1:
                   6638:              if(nagesqr==0)
                   6639:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   6640:              else /* nagesqr =1 */
                   6641:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   6642:              break;
                   6643:            case 2: /* ng=2 */
                   6644:              if(nagesqr==0)
                   6645:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   6646:              else /* nagesqr =1 */
                   6647:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   6648:              break;
                   6649:            case 3:
                   6650:              if(nagesqr==0)
                   6651:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   6652:              else /* nagesqr =1 */
                   6653:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   6654:              break;
                   6655:            }
                   6656:            ij=1;/* To be checked else nbcode[0][0] wrong */
                   6657:            for(j=3; j <=ncovmodel-nagesqr; j++) {
                   6658:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
                   6659:              if(ij <=cptcovage) { /* Bug valgrind */
                   6660:                if((j-2)==Tage[ij]) { /* Bug valgrind */
                   6661:                  fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                   6662:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   6663:                  ij++;
                   6664:                }
                   6665:              }
                   6666:              else
1.227     brouard  6667:                fprintf(ficgp,"+p%d*%d",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,j-2)]); /* Valgrind bug nbcode */
1.223     brouard  6668:            }
                   6669:          }else{
                   6670:            i=i-ncovmodel;
                   6671:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   6672:              fprintf(ficgp," (1.");
                   6673:          }
1.227     brouard  6674:          
1.223     brouard  6675:          if(ng != 1){
                   6676:            fprintf(ficgp,")/(1");
1.227     brouard  6677:            
1.223     brouard  6678:            for(k1=1; k1 <=nlstate; k1++){ 
                   6679:              if(nagesqr==0)
                   6680:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                   6681:              else /* nagesqr =1 */
                   6682:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1,k3+(k1-1)*ncovmodel+1+nagesqr);
1.217     brouard  6683:               
1.223     brouard  6684:              ij=1;
                   6685:              for(j=3; j <=ncovmodel-nagesqr; j++){
                   6686:                if(ij <=cptcovage) { /* Bug valgrind */
                   6687:                  if((j-2)==Tage[ij]) { /* Bug valgrind */
                   6688:                    fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                   6689:                    /* fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   6690:                    ij++;
                   6691:                  }
                   6692:                }
                   6693:                else
1.225     brouard  6694:                  fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  6695:              }
                   6696:              fprintf(ficgp,")");
                   6697:            }
                   6698:            fprintf(ficgp,")");
                   6699:            if(ng ==2)
                   6700:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   6701:            else /* ng= 3 */
                   6702:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   6703:          }else{ /* end ng <> 1 */
                   6704:            if( k !=k2) /* logit p11 is hard to draw */
                   6705:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   6706:          }
                   6707:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   6708:            fprintf(ficgp,",");
                   6709:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   6710:            fprintf(ficgp,",");
                   6711:          i=i+ncovmodel;
                   6712:        } /* end k */
                   6713:       } /* end k2 */
                   6714:       fprintf(ficgp,"\n set out\n");
                   6715:     } /* end jk */
                   6716:   } /* end ng */
                   6717:   /* avoid: */
                   6718:   fflush(ficgp); 
1.126     brouard  6719: }  /* end gnuplot */
                   6720: 
                   6721: 
                   6722: /*************** Moving average **************/
1.219     brouard  6723: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  6724:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  6725:    
1.222     brouard  6726:    int i, cpt, cptcod;
                   6727:    int modcovmax =1;
                   6728:    int mobilavrange, mob;
                   6729:    int iage=0;
                   6730: 
                   6731:    double sum=0.;
                   6732:    double age;
                   6733:    double *sumnewp, *sumnewm;
                   6734:    double *agemingood, *agemaxgood; /* Currently identical for all covariates */
                   6735:   
                   6736:   
1.225     brouard  6737:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  6738:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   6739: 
                   6740:    sumnewp = vector(1,ncovcombmax);
                   6741:    sumnewm = vector(1,ncovcombmax);
                   6742:    agemingood = vector(1,ncovcombmax); 
                   6743:    agemaxgood = vector(1,ncovcombmax);
                   6744: 
                   6745:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   6746:      sumnewm[cptcod]=0.;
                   6747:      sumnewp[cptcod]=0.;
                   6748:      agemingood[cptcod]=0;
                   6749:      agemaxgood[cptcod]=0;
                   6750:    }
                   6751:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   6752:   
                   6753:    if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   6754:      if(mobilav==1) mobilavrange=5; /* default */
                   6755:      else mobilavrange=mobilav;
                   6756:      for (age=bage; age<=fage; age++)
                   6757:        for (i=1; i<=nlstate;i++)
                   6758:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   6759:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   6760:      /* We keep the original values on the extreme ages bage, fage and for 
                   6761:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   6762:        we use a 5 terms etc. until the borders are no more concerned. 
                   6763:      */ 
                   6764:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   6765:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
                   6766:         for (i=1; i<=nlstate;i++){
                   6767:           for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   6768:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   6769:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   6770:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   6771:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   6772:             }
                   6773:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
                   6774:           }
                   6775:         }
                   6776:        }/* end age */
                   6777:      }/* end mob */
                   6778:    }else
                   6779:      return -1;
                   6780:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   6781:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   6782:      if(invalidvarcomb[cptcod]){
                   6783:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   6784:        continue;
                   6785:      }
1.219     brouard  6786: 
1.222     brouard  6787:      agemingood[cptcod]=fage-(mob-1)/2;
                   6788:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, finding the youngest wrong */
                   6789:        sumnewm[cptcod]=0.;
                   6790:        for (i=1; i<=nlstate;i++){
                   6791:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   6792:        }
                   6793:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   6794:         agemingood[cptcod]=age;
                   6795:        }else{ /* bad */
                   6796:         for (i=1; i<=nlstate;i++){
                   6797:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   6798:         } /* i */
                   6799:        } /* end bad */
                   6800:      }/* age */
                   6801:      sum=0.;
                   6802:      for (i=1; i<=nlstate;i++){
                   6803:        sum+=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   6804:      }
                   6805:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   6806:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any descending age!\n",cptcod);
                   6807:        /* for (i=1; i<=nlstate;i++){ */
                   6808:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   6809:        /* } /\* i *\/ */
                   6810:      } /* end bad */
                   6811:      /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   6812:      /* From youngest, finding the oldest wrong */
                   6813:      agemaxgood[cptcod]=bage+(mob-1)/2;
                   6814:      for (age=bage+(mob-1)/2; age<=fage; age++){
                   6815:        sumnewm[cptcod]=0.;
                   6816:        for (i=1; i<=nlstate;i++){
                   6817:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   6818:        }
                   6819:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   6820:         agemaxgood[cptcod]=age;
                   6821:        }else{ /* bad */
                   6822:         for (i=1; i<=nlstate;i++){
                   6823:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   6824:         } /* i */
                   6825:        } /* end bad */
                   6826:      }/* age */
                   6827:      sum=0.;
                   6828:      for (i=1; i<=nlstate;i++){
                   6829:        sum+=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   6830:      }
                   6831:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   6832:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any ascending age!\n",cptcod);
                   6833:        /* for (i=1; i<=nlstate;i++){ */
                   6834:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   6835:        /* } /\* i *\/ */
                   6836:      } /* end bad */
                   6837:                
                   6838:      for (age=bage; age<=fage; age++){
                   6839:        printf("%d %d ", cptcod, (int)age);
                   6840:        sumnewp[cptcod]=0.;
                   6841:        sumnewm[cptcod]=0.;
                   6842:        for (i=1; i<=nlstate;i++){
                   6843:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   6844:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   6845:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   6846:        }
                   6847:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   6848:      }
                   6849:      /* printf("\n"); */
                   6850:      /* } */
                   6851:      /* brutal averaging */
                   6852:      for (i=1; i<=nlstate;i++){
                   6853:        for (age=1; age<=bage; age++){
                   6854:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   6855:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   6856:        }       
                   6857:        for (age=fage; age<=AGESUP; age++){
                   6858:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   6859:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   6860:        }
                   6861:      } /* end i status */
                   6862:      for (i=nlstate+1; i<=nlstate+ndeath;i++){
                   6863:        for (age=1; age<=AGESUP; age++){
                   6864:         /*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*/
                   6865:         mobaverage[(int)age][i][cptcod]=0.;
                   6866:        }
                   6867:      }
                   6868:    }/* end cptcod */
                   6869:    free_vector(sumnewm,1, ncovcombmax);
                   6870:    free_vector(sumnewp,1, ncovcombmax);
                   6871:    free_vector(agemaxgood,1, ncovcombmax);
                   6872:    free_vector(agemingood,1, ncovcombmax);
                   6873:    return 0;
                   6874:  }/* End movingaverage */
1.218     brouard  6875:  
1.126     brouard  6876: 
                   6877: /************** Forecasting ******************/
1.225     brouard  6878: void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  6879:   /* proj1, year, month, day of starting projection 
                   6880:      agemin, agemax range of age
                   6881:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   6882:      anproj2 year of en of projection (same day and month as proj1).
                   6883:   */
1.164     brouard  6884:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1;
1.126     brouard  6885:   double agec; /* generic age */
                   6886:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   6887:   double *popeffectif,*popcount;
                   6888:   double ***p3mat;
1.218     brouard  6889:   /* double ***mobaverage; */
1.126     brouard  6890:   char fileresf[FILENAMELENGTH];
                   6891: 
                   6892:   agelim=AGESUP;
1.211     brouard  6893:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   6894:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   6895:      We still use firstpass and lastpass as another selection.
                   6896:   */
1.214     brouard  6897:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   6898:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  6899:  
1.201     brouard  6900:   strcpy(fileresf,"F_"); 
                   6901:   strcat(fileresf,fileresu);
1.126     brouard  6902:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   6903:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   6904:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   6905:   }
1.215     brouard  6906:   printf("Computing forecasting: result on file '%s', please wait... \n", fileresf);
                   6907:   fprintf(ficlog,"Computing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  6908: 
1.225     brouard  6909:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  6910: 
                   6911: 
                   6912:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   6913:   if (stepm<=12) stepsize=1;
                   6914:   if(estepm < stepm){
                   6915:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   6916:   }
                   6917:   else  hstepm=estepm;   
                   6918: 
                   6919:   hstepm=hstepm/stepm; 
                   6920:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   6921:                                fractional in yp1 */
                   6922:   anprojmean=yp;
                   6923:   yp2=modf((yp1*12),&yp);
                   6924:   mprojmean=yp;
                   6925:   yp1=modf((yp2*30.5),&yp);
                   6926:   jprojmean=yp;
                   6927:   if(jprojmean==0) jprojmean=1;
                   6928:   if(mprojmean==0) jprojmean=1;
                   6929: 
1.227     brouard  6930:   i1=pow(2,cptcoveff);
1.126     brouard  6931:   if (cptcovn < 1){i1=1;}
                   6932:   
                   6933:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   6934:   
                   6935:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  6936:   
1.126     brouard  6937: /*           if (h==(int)(YEARM*yearp)){ */
1.227     brouard  6938:   for(k=1;k<=i1;k++){
                   6939:     if(invalidvarcomb[k]){
                   6940:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   6941:       continue;
                   6942:     }
                   6943:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   6944:     for(j=1;j<=cptcoveff;j++) {
                   6945:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   6946:     }
                   6947:     fprintf(ficresf," yearproj age");
                   6948:     for(j=1; j<=nlstate+ndeath;j++){ 
                   6949:       for(i=1; i<=nlstate;i++)               
                   6950:        fprintf(ficresf," p%d%d",i,j);
                   6951:       fprintf(ficresf," wp.%d",j);
                   6952:     }
                   6953:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   6954:       fprintf(ficresf,"\n");
                   6955:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
                   6956:       for (agec=fage; agec>=(ageminpar-1); agec--){ 
                   6957:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   6958:        nhstepm = nhstepm/hstepm; 
                   6959:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6960:        oldm=oldms;savm=savms;
                   6961:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k);
                   6962:        
                   6963:        for (h=0; h<=nhstepm; h++){
                   6964:          if (h*hstepm/YEARM*stepm ==yearp) {
                   6965:            fprintf(ficresf,"\n");
                   6966:            for(j=1;j<=cptcoveff;j++) 
                   6967:              fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   6968:            fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   6969:          } 
                   6970:          for(j=1; j<=nlstate+ndeath;j++) {
                   6971:            ppij=0.;
                   6972:            for(i=1; i<=nlstate;i++) {
                   6973:              if (mobilav==1) 
                   6974:                ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][k];
                   6975:              else {
                   6976:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   6977:              }
                   6978:              if (h*hstepm/YEARM*stepm== yearp) {
                   6979:                fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   6980:              }
                   6981:            } /* end i */
                   6982:            if (h*hstepm/YEARM*stepm==yearp) {
                   6983:              fprintf(ficresf," %.3f", ppij);
                   6984:            }
                   6985:          }/* end j */
                   6986:        } /* end h */
                   6987:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6988:       } /* end agec */
                   6989:     } /* end yearp */
                   6990:   } /* end  k */
1.219     brouard  6991:        
1.126     brouard  6992:   fclose(ficresf);
1.215     brouard  6993:   printf("End of Computing forecasting \n");
                   6994:   fprintf(ficlog,"End of Computing forecasting\n");
                   6995: 
1.126     brouard  6996: }
                   6997: 
1.218     brouard  6998: /* /\************** Back Forecasting ******************\/ */
1.225     brouard  6999: /* void prevbackforecast(char fileres[], double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
1.218     brouard  7000: /*   /\* back1, year, month, day of starting backection  */
                   7001: /*      agemin, agemax range of age */
                   7002: /*      dateprev1 dateprev2 range of dates during which prevalence is computed */
                   7003: /*      anback2 year of en of backection (same day and month as back1). */
                   7004: /*   *\/ */
                   7005: /*   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1; */
                   7006: /*   double agec; /\* generic age *\/ */
                   7007: /*   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean; */
                   7008: /*   double *popeffectif,*popcount; */
                   7009: /*   double ***p3mat; */
                   7010: /*   /\* double ***mobaverage; *\/ */
                   7011: /*   char fileresfb[FILENAMELENGTH]; */
                   7012:        
                   7013: /*   agelim=AGESUP; */
                   7014: /*   /\* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people */
                   7015: /*      in each health status at the date of interview (if between dateprev1 and dateprev2). */
                   7016: /*      We still use firstpass and lastpass as another selection. */
                   7017: /*   *\/ */
                   7018: /*   /\* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ *\/ */
                   7019: /*   /\*             firstpass, lastpass,  stepm,  weightopt, model); *\/ */
                   7020: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   7021:        
                   7022: /*   strcpy(fileresfb,"FB_");  */
                   7023: /*   strcat(fileresfb,fileresu); */
                   7024: /*   if((ficresfb=fopen(fileresfb,"w"))==NULL) { */
                   7025: /*     printf("Problem with back forecast resultfile: %s\n", fileresfb); */
                   7026: /*     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb); */
                   7027: /*   } */
                   7028: /*   printf("Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7029: /*   fprintf(ficlog,"Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7030:        
1.225     brouard  7031: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.218     brouard  7032:        
                   7033: /*   /\* if (mobilav!=0) { *\/ */
                   7034: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7035: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7036: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7037: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7038: /*   /\*   } *\/ */
                   7039: /*   /\* } *\/ */
                   7040:        
                   7041: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7042: /*   if (stepm<=12) stepsize=1; */
                   7043: /*   if(estepm < stepm){ */
                   7044: /*     printf ("Problem %d lower than %d\n",estepm, stepm); */
                   7045: /*   } */
                   7046: /*   else  hstepm=estepm;    */
                   7047:        
                   7048: /*   hstepm=hstepm/stepm;  */
                   7049: /*   yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   7050: /*                                fractional in yp1 *\/ */
                   7051: /*   anprojmean=yp; */
                   7052: /*   yp2=modf((yp1*12),&yp); */
                   7053: /*   mprojmean=yp; */
                   7054: /*   yp1=modf((yp2*30.5),&yp); */
                   7055: /*   jprojmean=yp; */
                   7056: /*   if(jprojmean==0) jprojmean=1; */
                   7057: /*   if(mprojmean==0) jprojmean=1; */
                   7058:        
1.225     brouard  7059: /*   i1=cptcoveff; */
1.218     brouard  7060: /*   if (cptcovn < 1){i1=1;} */
1.217     brouard  7061:   
1.218     brouard  7062: /*   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);  */
1.217     brouard  7063:   
1.218     brouard  7064: /*   fprintf(ficresfb,"#****** Routine prevbackforecast **\n"); */
                   7065:        
                   7066: /*     /\*           if (h==(int)(YEARM*yearp)){ *\/ */
                   7067: /*   for(cptcov=1, k=0;cptcov<=i1;cptcov++){ */
1.225     brouard  7068: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
1.218     brouard  7069: /*       k=k+1; */
                   7070: /*       fprintf(ficresfb,"\n#****** hbijx=probability over h years, hp.jx is weighted by observed prev \n#"); */
1.225     brouard  7071: /*       for(j=1;j<=cptcoveff;j++) { */
1.218     brouard  7072: /*                             fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7073: /*       } */
                   7074: /*       fprintf(ficresfb," yearbproj age"); */
                   7075: /*       for(j=1; j<=nlstate+ndeath;j++){  */
                   7076: /*                             for(i=1; i<=nlstate;i++)               */
                   7077: /*           fprintf(ficresfb," p%d%d",i,j); */
                   7078: /*                             fprintf(ficresfb," p.%d",j); */
                   7079: /*       } */
                   7080: /*       for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {  */
                   7081: /*                             /\* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  *\/ */
                   7082: /*                             fprintf(ficresfb,"\n"); */
                   7083: /*                             fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);    */
                   7084: /*                             for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   7085: /*                                     nhstepm=(int) rint((agelim-agec)*YEARM/stepm);  */
                   7086: /*                                     nhstepm = nhstepm/hstepm;  */
                   7087: /*                                     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7088: /*                                     oldm=oldms;savm=savms; */
                   7089: /*                                     hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm,oldm,savm, dnewm, doldm, dsavm, k);       */
                   7090: /*                                     for (h=0; h<=nhstepm; h++){ */
                   7091: /*                                             if (h*hstepm/YEARM*stepm ==yearp) { */
                   7092: /*               fprintf(ficresfb,"\n"); */
1.225     brouard  7093: /*               for(j=1;j<=cptcoveff;j++)  */
1.218     brouard  7094: /*                 fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7095: /*                                                     fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec+h*hstepm/YEARM*stepm); */
                   7096: /*                                             }  */
                   7097: /*                                             for(j=1; j<=nlstate+ndeath;j++) { */
                   7098: /*                                                     ppij=0.; */
                   7099: /*                                                     for(i=1; i<=nlstate;i++) { */
                   7100: /*                                                             if (mobilav==1)  */
                   7101: /*                                                                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod]; */
                   7102: /*                                                             else { */
                   7103: /*                                                                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod]; */
                   7104: /*                                                             } */
                   7105: /*                                                             if (h*hstepm/YEARM*stepm== yearp) { */
                   7106: /*                                                                     fprintf(ficresfb," %.3f", p3mat[i][j][h]); */
                   7107: /*                                                             } */
                   7108: /*                                                     } /\* end i *\/ */
                   7109: /*                                                     if (h*hstepm/YEARM*stepm==yearp) { */
                   7110: /*                                                             fprintf(ficresfb," %.3f", ppij); */
                   7111: /*                                                     } */
                   7112: /*                                             }/\* end j *\/ */
                   7113: /*                                     } /\* end h *\/ */
                   7114: /*                                     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7115: /*                             } /\* end agec *\/ */
                   7116: /*       } /\* end yearp *\/ */
                   7117: /*     } /\* end cptcod *\/ */
                   7118: /*   } /\* end  cptcov *\/ */
                   7119:        
                   7120: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7121:        
                   7122: /*   fclose(ficresfb); */
                   7123: /*   printf("End of Computing Back forecasting \n"); */
                   7124: /*   fprintf(ficlog,"End of Computing Back forecasting\n"); */
1.217     brouard  7125:        
1.218     brouard  7126: /* } */
1.217     brouard  7127: 
1.126     brouard  7128: /************** Forecasting *****not tested NB*************/
1.227     brouard  7129: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  7130:   
1.227     brouard  7131: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   7132: /*   int *popage; */
                   7133: /*   double calagedatem, agelim, kk1, kk2; */
                   7134: /*   double *popeffectif,*popcount; */
                   7135: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   7136: /*   /\* double ***mobaverage; *\/ */
                   7137: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  7138: 
1.227     brouard  7139: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7140: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7141: /*   agelim=AGESUP; */
                   7142: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  7143:   
1.227     brouard  7144: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  7145:   
                   7146:   
1.227     brouard  7147: /*   strcpy(filerespop,"POP_");  */
                   7148: /*   strcat(filerespop,fileresu); */
                   7149: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   7150: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   7151: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   7152: /*   } */
                   7153: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   7154: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  7155: 
1.227     brouard  7156: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  7157: 
1.227     brouard  7158: /*   /\* if (mobilav!=0) { *\/ */
                   7159: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7160: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7161: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7162: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7163: /*   /\*   } *\/ */
                   7164: /*   /\* } *\/ */
1.126     brouard  7165: 
1.227     brouard  7166: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7167: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  7168:   
1.227     brouard  7169: /*   agelim=AGESUP; */
1.126     brouard  7170:   
1.227     brouard  7171: /*   hstepm=1; */
                   7172: /*   hstepm=hstepm/stepm;  */
1.218     brouard  7173:        
1.227     brouard  7174: /*   if (popforecast==1) { */
                   7175: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   7176: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   7177: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   7178: /*     }  */
                   7179: /*     popage=ivector(0,AGESUP); */
                   7180: /*     popeffectif=vector(0,AGESUP); */
                   7181: /*     popcount=vector(0,AGESUP); */
1.126     brouard  7182:     
1.227     brouard  7183: /*     i=1;    */
                   7184: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  7185:     
1.227     brouard  7186: /*     imx=i; */
                   7187: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   7188: /*   } */
1.218     brouard  7189:   
1.227     brouard  7190: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   7191: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   7192: /*       k=k+1; */
                   7193: /*       fprintf(ficrespop,"\n#******"); */
                   7194: /*       for(j=1;j<=cptcoveff;j++) { */
                   7195: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7196: /*       } */
                   7197: /*       fprintf(ficrespop,"******\n"); */
                   7198: /*       fprintf(ficrespop,"# Age"); */
                   7199: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   7200: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  7201:       
1.227     brouard  7202: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   7203: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  7204:        
1.227     brouard  7205: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7206: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7207: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7208:          
1.227     brouard  7209: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7210: /*       oldm=oldms;savm=savms; */
                   7211: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  7212:          
1.227     brouard  7213: /*       for (h=0; h<=nhstepm; h++){ */
                   7214: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7215: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7216: /*         }  */
                   7217: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7218: /*           kk1=0.;kk2=0; */
                   7219: /*           for(i=1; i<=nlstate;i++) {               */
                   7220: /*             if (mobilav==1)  */
                   7221: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   7222: /*             else { */
                   7223: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   7224: /*             } */
                   7225: /*           } */
                   7226: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   7227: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   7228: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   7229: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   7230: /*           } */
                   7231: /*         } */
                   7232: /*         for(i=1; i<=nlstate;i++){ */
                   7233: /*           kk1=0.; */
                   7234: /*           for(j=1; j<=nlstate;j++){ */
                   7235: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   7236: /*           } */
                   7237: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   7238: /*         } */
1.218     brouard  7239:            
1.227     brouard  7240: /*         if (h==(int)(calagedatem+12*cpt)) */
                   7241: /*           for(j=1; j<=nlstate;j++)  */
                   7242: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   7243: /*       } */
                   7244: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7245: /*     } */
                   7246: /*       } */
1.218     brouard  7247:       
1.227     brouard  7248: /*       /\******\/ */
1.218     brouard  7249:       
1.227     brouard  7250: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   7251: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   7252: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7253: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7254: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7255:          
1.227     brouard  7256: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7257: /*       oldm=oldms;savm=savms; */
                   7258: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   7259: /*       for (h=0; h<=nhstepm; h++){ */
                   7260: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7261: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7262: /*         }  */
                   7263: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7264: /*           kk1=0.;kk2=0; */
                   7265: /*           for(i=1; i<=nlstate;i++) {               */
                   7266: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   7267: /*           } */
                   7268: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   7269: /*         } */
                   7270: /*       } */
                   7271: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7272: /*     } */
                   7273: /*       } */
                   7274: /*     }  */
                   7275: /*   } */
1.218     brouard  7276:   
1.227     brouard  7277: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  7278:   
1.227     brouard  7279: /*   if (popforecast==1) { */
                   7280: /*     free_ivector(popage,0,AGESUP); */
                   7281: /*     free_vector(popeffectif,0,AGESUP); */
                   7282: /*     free_vector(popcount,0,AGESUP); */
                   7283: /*   } */
                   7284: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7285: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7286: /*   fclose(ficrespop); */
                   7287: /* } /\* End of popforecast *\/ */
1.218     brouard  7288:  
1.126     brouard  7289: int fileappend(FILE *fichier, char *optionfich)
                   7290: {
                   7291:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   7292:     printf("Problem with file: %s\n", optionfich);
                   7293:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   7294:     return (0);
                   7295:   }
                   7296:   fflush(fichier);
                   7297:   return (1);
                   7298: }
                   7299: 
                   7300: 
                   7301: /**************** function prwizard **********************/
                   7302: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   7303: {
                   7304: 
                   7305:   /* Wizard to print covariance matrix template */
                   7306: 
1.164     brouard  7307:   char ca[32], cb[32];
                   7308:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  7309:   int numlinepar;
                   7310: 
                   7311:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7312:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7313:   for(i=1; i <=nlstate; i++){
                   7314:     jj=0;
                   7315:     for(j=1; j <=nlstate+ndeath; j++){
                   7316:       if(j==i) continue;
                   7317:       jj++;
                   7318:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   7319:       printf("%1d%1d",i,j);
                   7320:       fprintf(ficparo,"%1d%1d",i,j);
                   7321:       for(k=1; k<=ncovmodel;k++){
                   7322:        /*        printf(" %lf",param[i][j][k]); */
                   7323:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   7324:        printf(" 0.");
                   7325:        fprintf(ficparo," 0.");
                   7326:       }
                   7327:       printf("\n");
                   7328:       fprintf(ficparo,"\n");
                   7329:     }
                   7330:   }
                   7331:   printf("# Scales (for hessian or gradient estimation)\n");
                   7332:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   7333:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   7334:   for(i=1; i <=nlstate; i++){
                   7335:     jj=0;
                   7336:     for(j=1; j <=nlstate+ndeath; j++){
                   7337:       if(j==i) continue;
                   7338:       jj++;
                   7339:       fprintf(ficparo,"%1d%1d",i,j);
                   7340:       printf("%1d%1d",i,j);
                   7341:       fflush(stdout);
                   7342:       for(k=1; k<=ncovmodel;k++){
                   7343:        /*      printf(" %le",delti3[i][j][k]); */
                   7344:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   7345:        printf(" 0.");
                   7346:        fprintf(ficparo," 0.");
                   7347:       }
                   7348:       numlinepar++;
                   7349:       printf("\n");
                   7350:       fprintf(ficparo,"\n");
                   7351:     }
                   7352:   }
                   7353:   printf("# Covariance matrix\n");
                   7354: /* # 121 Var(a12)\n\ */
                   7355: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7356: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   7357: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   7358: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   7359: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   7360: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   7361: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   7362:   fflush(stdout);
                   7363:   fprintf(ficparo,"# Covariance matrix\n");
                   7364:   /* # 121 Var(a12)\n\ */
                   7365:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7366:   /* #   ...\n\ */
                   7367:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   7368:   
                   7369:   for(itimes=1;itimes<=2;itimes++){
                   7370:     jj=0;
                   7371:     for(i=1; i <=nlstate; i++){
                   7372:       for(j=1; j <=nlstate+ndeath; j++){
                   7373:        if(j==i) continue;
                   7374:        for(k=1; k<=ncovmodel;k++){
                   7375:          jj++;
                   7376:          ca[0]= k+'a'-1;ca[1]='\0';
                   7377:          if(itimes==1){
                   7378:            printf("#%1d%1d%d",i,j,k);
                   7379:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   7380:          }else{
                   7381:            printf("%1d%1d%d",i,j,k);
                   7382:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   7383:            /*  printf(" %.5le",matcov[i][j]); */
                   7384:          }
                   7385:          ll=0;
                   7386:          for(li=1;li <=nlstate; li++){
                   7387:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   7388:              if(lj==li) continue;
                   7389:              for(lk=1;lk<=ncovmodel;lk++){
                   7390:                ll++;
                   7391:                if(ll<=jj){
                   7392:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   7393:                  if(ll<jj){
                   7394:                    if(itimes==1){
                   7395:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7396:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7397:                    }else{
                   7398:                      printf(" 0.");
                   7399:                      fprintf(ficparo," 0.");
                   7400:                    }
                   7401:                  }else{
                   7402:                    if(itimes==1){
                   7403:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   7404:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   7405:                    }else{
                   7406:                      printf(" 0.");
                   7407:                      fprintf(ficparo," 0.");
                   7408:                    }
                   7409:                  }
                   7410:                }
                   7411:              } /* end lk */
                   7412:            } /* end lj */
                   7413:          } /* end li */
                   7414:          printf("\n");
                   7415:          fprintf(ficparo,"\n");
                   7416:          numlinepar++;
                   7417:        } /* end k*/
                   7418:       } /*end j */
                   7419:     } /* end i */
                   7420:   } /* end itimes */
                   7421: 
                   7422: } /* end of prwizard */
                   7423: /******************* Gompertz Likelihood ******************************/
                   7424: double gompertz(double x[])
                   7425: { 
                   7426:   double A,B,L=0.0,sump=0.,num=0.;
                   7427:   int i,n=0; /* n is the size of the sample */
                   7428: 
1.220     brouard  7429:   for (i=1;i<=imx ; i++) {
1.126     brouard  7430:     sump=sump+weight[i];
                   7431:     /*    sump=sump+1;*/
                   7432:     num=num+1;
                   7433:   }
                   7434:  
                   7435:  
                   7436:   /* for (i=0; i<=imx; i++) 
                   7437:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   7438: 
                   7439:   for (i=1;i<=imx ; i++)
                   7440:     {
                   7441:       if (cens[i] == 1 && wav[i]>1)
                   7442:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   7443:       
                   7444:       if (cens[i] == 0 && wav[i]>1)
                   7445:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   7446:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   7447:       
                   7448:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   7449:       if (wav[i] > 1 ) { /* ??? */
                   7450:        L=L+A*weight[i];
                   7451:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   7452:       }
                   7453:     }
                   7454: 
                   7455:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   7456:  
                   7457:   return -2*L*num/sump;
                   7458: }
                   7459: 
1.136     brouard  7460: #ifdef GSL
                   7461: /******************* Gompertz_f Likelihood ******************************/
                   7462: double gompertz_f(const gsl_vector *v, void *params)
                   7463: { 
                   7464:   double A,B,LL=0.0,sump=0.,num=0.;
                   7465:   double *x= (double *) v->data;
                   7466:   int i,n=0; /* n is the size of the sample */
                   7467: 
                   7468:   for (i=0;i<=imx-1 ; i++) {
                   7469:     sump=sump+weight[i];
                   7470:     /*    sump=sump+1;*/
                   7471:     num=num+1;
                   7472:   }
                   7473:  
                   7474:  
                   7475:   /* for (i=0; i<=imx; i++) 
                   7476:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   7477:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   7478:   for (i=1;i<=imx ; i++)
                   7479:     {
                   7480:       if (cens[i] == 1 && wav[i]>1)
                   7481:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   7482:       
                   7483:       if (cens[i] == 0 && wav[i]>1)
                   7484:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   7485:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   7486:       
                   7487:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   7488:       if (wav[i] > 1 ) { /* ??? */
                   7489:        LL=LL+A*weight[i];
                   7490:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   7491:       }
                   7492:     }
                   7493: 
                   7494:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   7495:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   7496:  
                   7497:   return -2*LL*num/sump;
                   7498: }
                   7499: #endif
                   7500: 
1.126     brouard  7501: /******************* Printing html file ***********/
1.201     brouard  7502: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  7503:                  int lastpass, int stepm, int weightopt, char model[],\
                   7504:                  int imx,  double p[],double **matcov,double agemortsup){
                   7505:   int i,k;
                   7506: 
                   7507:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   7508:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   7509:   for (i=1;i<=2;i++) 
                   7510:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  7511:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  7512:   fprintf(fichtm,"</ul>");
                   7513: 
                   7514: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   7515: 
                   7516:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   7517: 
                   7518:  for (k=agegomp;k<(agemortsup-2);k++) 
                   7519:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   7520: 
                   7521:  
                   7522:   fflush(fichtm);
                   7523: }
                   7524: 
                   7525: /******************* Gnuplot file **************/
1.201     brouard  7526: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  7527: 
                   7528:   char dirfileres[132],optfileres[132];
1.164     brouard  7529: 
1.126     brouard  7530:   int ng;
                   7531: 
                   7532: 
                   7533:   /*#ifdef windows */
                   7534:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   7535:     /*#endif */
                   7536: 
                   7537: 
                   7538:   strcpy(dirfileres,optionfilefiname);
                   7539:   strcpy(optfileres,"vpl");
1.199     brouard  7540:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  7541:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  7542:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  7543:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  7544:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   7545: 
                   7546: } 
                   7547: 
1.136     brouard  7548: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   7549: {
1.126     brouard  7550: 
1.136     brouard  7551:   /*-------- data file ----------*/
                   7552:   FILE *fic;
                   7553:   char dummy[]="                         ";
1.223     brouard  7554:   int i=0, j=0, n=0, iv=0;
                   7555:   int lstra;
1.136     brouard  7556:   int linei, month, year,iout;
                   7557:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  7558:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  7559:   char *stratrunc;
1.223     brouard  7560: 
1.126     brouard  7561: 
                   7562: 
1.136     brouard  7563:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  7564:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   7565:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  7566:   }
1.126     brouard  7567: 
1.136     brouard  7568:   i=1;
                   7569:   linei=0;
                   7570:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   7571:     linei=linei+1;
                   7572:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   7573:       if(line[j] == '\t')
                   7574:        line[j] = ' ';
                   7575:     }
                   7576:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   7577:       ;
                   7578:     };
                   7579:     line[j+1]=0;  /* Trims blanks at end of line */
                   7580:     if(line[0]=='#'){
                   7581:       fprintf(ficlog,"Comment line\n%s\n",line);
                   7582:       printf("Comment line\n%s\n",line);
                   7583:       continue;
                   7584:     }
                   7585:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  7586:     strcpy(line, linetmp);
1.223     brouard  7587:     
                   7588:     /* Loops on waves */
                   7589:     for (j=maxwav;j>=1;j--){
                   7590:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.225     brouard  7591:        cutv(stra, strb, line, ' '); 
                   7592:        if(strb[0]=='.') { /* Missing value */
                   7593:          lval=-1;
                   7594:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   7595:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   7596:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   7597:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   7598:            return 1;
                   7599:          }
                   7600:        }else{
                   7601:          errno=0;
                   7602:          /* what_kind_of_number(strb); */
                   7603:          dval=strtod(strb,&endptr); 
                   7604:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   7605:          /* if(strb != endptr && *endptr == '\0') */
                   7606:          /*    dval=dlval; */
                   7607:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   7608:          if( strb[0]=='\0' || (*endptr != '\0')){
                   7609:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   7610:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   7611:            return 1;
                   7612:          }
                   7613:          cotqvar[j][iv][i]=dval; 
                   7614:        }
                   7615:        strcpy(line,stra);
1.223     brouard  7616:       }/* end loop ntqv */
1.225     brouard  7617:       
1.223     brouard  7618:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.225     brouard  7619:        cutv(stra, strb, line, ' '); 
                   7620:        if(strb[0]=='.') { /* Missing value */
                   7621:          lval=-1;
                   7622:        }else{
                   7623:          errno=0;
                   7624:          lval=strtol(strb,&endptr,10); 
                   7625:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   7626:          if( strb[0]=='\0' || (*endptr != '\0')){
                   7627:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   7628:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   7629:            return 1;
                   7630:          }
                   7631:        }
                   7632:        if(lval <-1 || lval >1){
                   7633:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  7634:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   7635:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  7636:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   7637:  build V1=0 V2=0 for the reference value (1),\n                                \
                   7638:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  7639:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  7640:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  7641:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  7642:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  7643:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   7644:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  7645:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   7646:  build V1=0 V2=0 for the reference value (1),\n                                \
                   7647:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  7648:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
                   7649:  output of IMaCh is often meaningless.\n                               \
                   7650:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  7651:          return 1;
                   7652:        }
                   7653:        cotvar[j][iv][i]=(double)(lval);
                   7654:        strcpy(line,stra);
1.223     brouard  7655:       }/* end loop ntv */
1.225     brouard  7656:       
1.223     brouard  7657:       /* Statuses  at wave */
1.137     brouard  7658:       cutv(stra, strb, line, ' '); 
1.223     brouard  7659:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  7660:        lval=-1;
1.136     brouard  7661:       }else{
1.225     brouard  7662:        errno=0;
                   7663:        lval=strtol(strb,&endptr,10); 
                   7664:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   7665:        if( strb[0]=='\0' || (*endptr != '\0')){
                   7666:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   7667:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   7668:          return 1;
                   7669:        }
1.136     brouard  7670:       }
1.225     brouard  7671:       
1.136     brouard  7672:       s[j][i]=lval;
1.225     brouard  7673:       
1.223     brouard  7674:       /* Date of Interview */
1.136     brouard  7675:       strcpy(line,stra);
                   7676:       cutv(stra, strb,line,' ');
1.169     brouard  7677:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  7678:       }
1.169     brouard  7679:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  7680:        month=99;
                   7681:        year=9999;
1.136     brouard  7682:       }else{
1.225     brouard  7683:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   7684:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   7685:        return 1;
1.136     brouard  7686:       }
                   7687:       anint[j][i]= (double) year; 
                   7688:       mint[j][i]= (double)month; 
                   7689:       strcpy(line,stra);
1.223     brouard  7690:     } /* End loop on waves */
1.225     brouard  7691:     
1.223     brouard  7692:     /* Date of death */
1.136     brouard  7693:     cutv(stra, strb,line,' '); 
1.169     brouard  7694:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  7695:     }
1.169     brouard  7696:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  7697:       month=99;
                   7698:       year=9999;
                   7699:     }else{
1.141     brouard  7700:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  7701:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   7702:       return 1;
1.136     brouard  7703:     }
                   7704:     andc[i]=(double) year; 
                   7705:     moisdc[i]=(double) month; 
                   7706:     strcpy(line,stra);
                   7707:     
1.223     brouard  7708:     /* Date of birth */
1.136     brouard  7709:     cutv(stra, strb,line,' '); 
1.169     brouard  7710:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  7711:     }
1.169     brouard  7712:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  7713:       month=99;
                   7714:       year=9999;
                   7715:     }else{
1.141     brouard  7716:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   7717:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  7718:       return 1;
1.136     brouard  7719:     }
                   7720:     if (year==9999) {
1.141     brouard  7721:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   7722:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  7723:       return 1;
                   7724:       
1.136     brouard  7725:     }
                   7726:     annais[i]=(double)(year);
                   7727:     moisnais[i]=(double)(month); 
                   7728:     strcpy(line,stra);
1.225     brouard  7729:     
1.223     brouard  7730:     /* Sample weight */
1.136     brouard  7731:     cutv(stra, strb,line,' '); 
                   7732:     errno=0;
                   7733:     dval=strtod(strb,&endptr); 
                   7734:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  7735:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   7736:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  7737:       fflush(ficlog);
                   7738:       return 1;
                   7739:     }
                   7740:     weight[i]=dval; 
                   7741:     strcpy(line,stra);
1.225     brouard  7742:     
1.223     brouard  7743:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   7744:       cutv(stra, strb, line, ' '); 
                   7745:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  7746:        lval=-1;
1.223     brouard  7747:       }else{
1.225     brouard  7748:        errno=0;
                   7749:        /* what_kind_of_number(strb); */
                   7750:        dval=strtod(strb,&endptr);
                   7751:        /* if(strb != endptr && *endptr == '\0') */
                   7752:        /*   dval=dlval; */
                   7753:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   7754:        if( strb[0]=='\0' || (*endptr != '\0')){
                   7755:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   7756:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   7757:          return 1;
                   7758:        }
                   7759:        coqvar[iv][i]=dval; 
1.226     brouard  7760:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  7761:       }
                   7762:       strcpy(line,stra);
                   7763:     }/* end loop nqv */
1.136     brouard  7764:     
1.223     brouard  7765:     /* Covariate values */
1.136     brouard  7766:     for (j=ncovcol;j>=1;j--){
                   7767:       cutv(stra, strb,line,' '); 
1.223     brouard  7768:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  7769:        lval=-1;
1.136     brouard  7770:       }else{
1.225     brouard  7771:        errno=0;
                   7772:        lval=strtol(strb,&endptr,10); 
                   7773:        if( strb[0]=='\0' || (*endptr != '\0')){
                   7774:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   7775:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   7776:          return 1;
                   7777:        }
1.136     brouard  7778:       }
                   7779:       if(lval <-1 || lval >1){
1.225     brouard  7780:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  7781:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   7782:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  7783:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   7784:  build V1=0 V2=0 for the reference value (1),\n                                \
                   7785:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  7786:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  7787:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  7788:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  7789:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  7790:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   7791:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  7792:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   7793:  build V1=0 V2=0 for the reference value (1),\n                                \
                   7794:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  7795:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  7796:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  7797:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  7798:        return 1;
1.136     brouard  7799:       }
                   7800:       covar[j][i]=(double)(lval);
                   7801:       strcpy(line,stra);
                   7802:     }  
                   7803:     lstra=strlen(stra);
1.225     brouard  7804:     
1.136     brouard  7805:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   7806:       stratrunc = &(stra[lstra-9]);
                   7807:       num[i]=atol(stratrunc);
                   7808:     }
                   7809:     else
                   7810:       num[i]=atol(stra);
                   7811:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   7812:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   7813:     
                   7814:     i=i+1;
                   7815:   } /* End loop reading  data */
1.225     brouard  7816:   
1.136     brouard  7817:   *imax=i-1; /* Number of individuals */
                   7818:   fclose(fic);
1.225     brouard  7819:   
1.136     brouard  7820:   return (0);
1.164     brouard  7821:   /* endread: */
1.225     brouard  7822:   printf("Exiting readdata: ");
                   7823:   fclose(fic);
                   7824:   return (1);
1.223     brouard  7825: }
1.126     brouard  7826: 
1.230     brouard  7827: void removespace(char **stri){/*, char stro[]) {*/
                   7828:   char *p1 = *stri, *p2 = *stri;
1.145     brouard  7829:   do
                   7830:     while (*p2 == ' ')
                   7831:       p2++;
1.169     brouard  7832:   while (*p1++ == *p2++);
1.230     brouard  7833:   *stri=p1; 
1.145     brouard  7834: }
                   7835: 
1.230     brouard  7836: int decoderesult ( char resultline[])
                   7837: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   7838: {
                   7839:   int j=0, k=0;
                   7840:   char resultsav[MAXLINE];
                   7841:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   7842: 
                   7843:   removespace(&resultline);
                   7844:   printf("decoderesult=%s\n",resultline);
                   7845: 
                   7846:   if (strstr(resultline,"v") !=0){
                   7847:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   7848:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   7849:     return 1;
                   7850:   }
                   7851:   trimbb(resultsav, resultline);
                   7852:   if (strlen(resultsav) >1){
                   7853:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   7854:   }
                   7855: 
                   7856:   for(k=1; k<=j;k++){ /* Loop on total covariates of the model */
                   7857:     cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   7858:                                     resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   7859:     cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   7860:     Tvalsel[k]=atof(strc); /* 1 */
                   7861: 
                   7862:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   7863:     Tvarsel[k]=atoi(strc);
                   7864:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   7865:     /* cptcovsel++;     */
                   7866:     if (nbocc(stra,'=') >0)
                   7867:       strcpy(resultsav,stra); /* and analyzes it */
                   7868:   }
                   7869:   return (0);
                   7870: }
                   7871: int selected( int kvar){ /* Selected combination of covariates */
                   7872:   if(Tvarsel[kvar])
                   7873:     return (0);
                   7874:   else
                   7875:     return(1);
                   7876: }
                   7877: int decodemodel( char model[], int lastobs)
                   7878:  /**< This routine decodes the model and returns:
1.224     brouard  7879:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   7880:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   7881:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   7882:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   7883:        * - cptcovage number of covariates with age*products =2
                   7884:        * - cptcovs number of simple covariates
                   7885:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   7886:        *     which is a new column after the 9 (ncovcol) variables. 
                   7887:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   7888:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   7889:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   7890:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   7891:        */
1.136     brouard  7892: {
1.145     brouard  7893:   int i, j, k, ks;
1.227     brouard  7894:   int  j1, k1, k2, k3, k4;
1.136     brouard  7895:   char modelsav[80];
1.145     brouard  7896:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  7897:   char *strpt;
1.136     brouard  7898: 
1.145     brouard  7899:   /*removespace(model);*/
1.136     brouard  7900:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  7901:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  7902:     if (strstr(model,"AGE") !=0){
1.192     brouard  7903:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   7904:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  7905:       return 1;
                   7906:     }
1.141     brouard  7907:     if (strstr(model,"v") !=0){
                   7908:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   7909:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   7910:       return 1;
                   7911:     }
1.187     brouard  7912:     strcpy(modelsav,model); 
                   7913:     if ((strpt=strstr(model,"age*age")) !=0){
                   7914:       printf(" strpt=%s, model=%s\n",strpt, model);
                   7915:       if(strpt != model){
1.231   ! brouard  7916:                                printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  7917:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  7918:  corresponding column of parameters.\n",model);
1.231   ! brouard  7919:                                fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  7920:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  7921:  corresponding column of parameters.\n",model); fflush(ficlog);
1.231   ! brouard  7922:                                return 1;
1.225     brouard  7923:       }
1.187     brouard  7924:       nagesqr=1;
                   7925:       if (strstr(model,"+age*age") !=0)
1.231   ! brouard  7926:                                substrchaine(modelsav, model, "+age*age");
1.187     brouard  7927:       else if (strstr(model,"age*age+") !=0)
1.231   ! brouard  7928:                                substrchaine(modelsav, model, "age*age+");
1.187     brouard  7929:       else 
1.231   ! brouard  7930:                                substrchaine(modelsav, model, "age*age");
1.187     brouard  7931:     }else
                   7932:       nagesqr=0;
                   7933:     if (strlen(modelsav) >1){
                   7934:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   7935:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  7936:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  7937:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  7938:                     * cst, age and age*age 
                   7939:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   7940:       /* including age products which are counted in cptcovage.
                   7941:        * but the covariates which are products must be treated 
                   7942:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  7943:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   7944:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  7945:       
                   7946:       
1.187     brouard  7947:       /*   Design
                   7948:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   7949:        *  <          ncovcol=8                >
                   7950:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   7951:        *   k=  1    2      3       4     5       6      7        8
                   7952:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   7953:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  7954:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   7955:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  7956:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   7957:        *  Tage[++cptcovage]=k
                   7958:        *       if products, new covar are created after ncovcol with k1
                   7959:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   7960:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   7961:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   7962:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   7963:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   7964:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   7965:        *  <          ncovcol=8                >
                   7966:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   7967:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   7968:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   7969:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   7970:        * p Tprod[1]@2={                         6, 5}
                   7971:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   7972:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   7973:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   7974:        *How to reorganize?
                   7975:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   7976:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   7977:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   7978:        * Struct []
                   7979:        */
1.225     brouard  7980:       
1.187     brouard  7981:       /* This loop fills the array Tvar from the string 'model'.*/
                   7982:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   7983:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   7984:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   7985:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   7986:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   7987:       /*       k=1 Tvar[1]=2 (from V2) */
                   7988:       /*       k=5 Tvar[5] */
                   7989:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  7990:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  7991:       /*       } */
1.198     brouard  7992:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  7993:       /*
                   7994:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  7995:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   7996:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   7997:       }
1.187     brouard  7998:       cptcovage=0;
                   7999:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.225     brouard  8000:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
                   8001:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
                   8002:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   8003:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   8004:        /*scanf("%d",i);*/
                   8005:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   8006:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   8007:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   8008:            /* covar is not filled and then is empty */
                   8009:            cptcovprod--;
                   8010:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   8011:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
1.226     brouard  8012:            Typevar[k]=1;  /* 1 for age product */
1.225     brouard  8013:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   8014:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   8015:            /*printf("stre=%s ", stre);*/
                   8016:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   8017:            cptcovprod--;
                   8018:            cutl(stre,strb,strc,'V');
                   8019:            Tvar[k]=atoi(stre);
                   8020:            Typevar[k]=1;  /* 1 for age product */
                   8021:            cptcovage++;
                   8022:            Tage[cptcovage]=k;
                   8023:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   8024:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   8025:            cptcovn++;
                   8026:            cptcovprodnoage++;k1++;
                   8027:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   8028:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   8029:                                   because this model-covariate is a construction we invent a new column
                   8030:                                   which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   8031:                                   If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   8032:                                   Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   8033:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   8034:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   8035:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
1.227     brouard  8036:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
1.225     brouard  8037:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   8038:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   8039:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   8040:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   8041:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
                   8042:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
                   8043:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   8044:            for (i=1; i<=lastobs;i++){
                   8045:              /* Computes the new covariate which is a product of
                   8046:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   8047:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   8048:            }
                   8049:          } /* End age is not in the model */
                   8050:        } /* End if model includes a product */
                   8051:        else { /* no more sum */
                   8052:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   8053:          /*  scanf("%d",i);*/
                   8054:          cutl(strd,strc,strb,'V');
1.227     brouard  8055:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
1.225     brouard  8056:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   8057:          Tvar[k]=atoi(strd);
                   8058:          Typevar[k]=0;  /* 0 for simple covariates */
                   8059:        }
                   8060:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  8061:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  8062:                                  scanf("%d",i);*/
1.187     brouard  8063:       } /* end of loop + on total covariates */
                   8064:     } /* end if strlen(modelsave == 0) age*age might exist */
                   8065:   } /* end if strlen(model == 0) */
1.136     brouard  8066:   
                   8067:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   8068:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  8069:   
1.136     brouard  8070:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  8071:      printf("cptcovprod=%d ", cptcovprod);
                   8072:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   8073:      scanf("%d ",i);*/
                   8074: 
                   8075: 
1.230     brouard  8076: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   8077:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  8078: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   8079:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   8080:    k =           1    2   3     4       5       6      7      8        9
                   8081:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   8082:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  8083:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   8084:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   8085:          Tmodelind[combination of covar]=k;
1.225     brouard  8086: */  
                   8087: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  8088:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  8089:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  8090:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  8091:   printf("Model=%s\n\
                   8092: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8093: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8094: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8095:   fprintf(ficlog,"Model=%s\n\
                   8096: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8097: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8098: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8099: 
1.225     brouard  8100:   for(k=1, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
1.231   ! brouard  8101:     if (Tvar[k] <=ncovcol && (Typevar[k]==0 || Typevar[k]==2)){ /* Simple or product fixed dummy (<=ncovcol) covariates */
1.227     brouard  8102:       Fixed[k]= 0;
                   8103:       Dummy[k]= 0;
1.225     brouard  8104:       ncoveff++;
1.231   ! brouard  8105:                        modell[k].maintype= FTYPE;
1.230     brouard  8106:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231   ! brouard  8107:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
        !          8108:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){ /* Remind that product Vn*Vm are added in k*/ /* Only simple fixed quantitative variable */
1.227     brouard  8109:       Fixed[k]= 0;
                   8110:       Dummy[k]= 1;
1.230     brouard  8111:       nqfveff++;
1.231   ! brouard  8112:                        modell[k].maintype= FTYPE;
        !          8113:                        modell[k].subtype= FQ;
        !          8114:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  8115:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.225     brouard  8116:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){
1.227     brouard  8117:       Fixed[k]= 1;
                   8118:       Dummy[k]= 0;
1.225     brouard  8119:       ntveff++; /* Only simple time varying dummy variable */
1.231   ! brouard  8120:                        modell[k].maintype= VTYPE;
        !          8121:                        modell[k].subtype= VD;
        !          8122:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
        !          8123:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  8124:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   8125:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231   ! brouard  8126:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
        !          8127:                        Fixed[k]= 1;
        !          8128:                        Dummy[k]= 1;
        !          8129:                        nqtveff++;
        !          8130:                        modell[k].maintype= VTYPE;
        !          8131:                        modell[k].subtype= VQ;
        !          8132:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
        !          8133:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
        !          8134:                        TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
        !          8135:                        /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
        !          8136:                        printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  8137:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  8138:     }else if (Typevar[k] == 1) {  /* product with age */
1.231   ! brouard  8139:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
        !          8140:                                Fixed[k]= 2;
        !          8141:                                Dummy[k]= 2;
        !          8142:                                modell[k].maintype= ATYPE;
        !          8143:                                modell[k].subtype= APFD;
        !          8144:                                /* ncoveff++; */
1.227     brouard  8145:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.231   ! brouard  8146:                                Fixed[k]= 2;
        !          8147:                                Dummy[k]= 3;
        !          8148:                                modell[k].maintype= ATYPE;
        !          8149:                                modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
        !          8150:                                /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  8151:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.231   ! brouard  8152:                                Fixed[k]= 3;
        !          8153:                                Dummy[k]= 2;
        !          8154:                                modell[k].maintype= ATYPE;
        !          8155:                                modell[k].subtype= APVD;                /*      Product age * varying dummy */
        !          8156:                                /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  8157:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.231   ! brouard  8158:                                Fixed[k]= 3;
        !          8159:                                Dummy[k]= 3;
        !          8160:                                modell[k].maintype= ATYPE;
        !          8161:                                modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
        !          8162:                                /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  8163:       }
                   8164:     }else if (Typevar[k] == 2) {  /* product without age */
                   8165:       k1=Tposprod[k];
                   8166:       if(Tvard[k1][1] <=ncovcol){
1.231   ! brouard  8167:                                if(Tvard[k1][2] <=ncovcol){
        !          8168:                                        Fixed[k]= 1;
        !          8169:                                        Dummy[k]= 0;
        !          8170:                                        modell[k].maintype= FTYPE;
        !          8171:                                        modell[k].subtype= FPDD;                /*      Product fixed dummy * fixed dummy */
        !          8172:                                }else if(Tvard[k1][2] <=ncovcol+nqv){
        !          8173:                                        Fixed[k]= 0;  /* or 2 ?*/
        !          8174:                                        Dummy[k]= 1;
        !          8175:                                        modell[k].maintype= FTYPE;
        !          8176:                                        modell[k].subtype= FPDQ;                /*      Product fixed dummy * fixed quantitative */
        !          8177:                                }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
        !          8178:                                        Fixed[k]= 1;
        !          8179:                                        Dummy[k]= 0;
        !          8180:                                        modell[k].maintype= VTYPE;
        !          8181:                                        modell[k].subtype= VPDD;                /*      Product fixed dummy * varying dummy */
        !          8182:                                }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
        !          8183:                                        Fixed[k]= 1;
        !          8184:                                        Dummy[k]= 1;
        !          8185:                                        modell[k].maintype= VTYPE;
        !          8186:                                        modell[k].subtype= VPDQ;                /*      Product fixed dummy * varying quantitative */
        !          8187:                                } 
1.227     brouard  8188:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.231   ! brouard  8189:                                if(Tvard[k1][2] <=ncovcol){
        !          8190:                                        Fixed[k]= 0;  /* or 2 ?*/
        !          8191:                                        Dummy[k]= 1;
        !          8192:                                        modell[k].maintype= FTYPE;
        !          8193:                                        modell[k].subtype= FPDQ;                /*      Product fixed quantitative * fixed dummy */
        !          8194:                                }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
        !          8195:                                        Fixed[k]= 1;
        !          8196:                                        Dummy[k]= 1;
        !          8197:                                        modell[k].maintype= VTYPE;
        !          8198:                                        modell[k].subtype= VPDQ;                /*      Product fixed quantitative * varying dummy */
        !          8199:                                }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
        !          8200:                                        Fixed[k]= 1;
        !          8201:                                        Dummy[k]= 1;
        !          8202:                                        modell[k].maintype= VTYPE;
        !          8203:                                        modell[k].subtype= VPQQ;                /*      Product fixed quantitative * varying quantitative */
        !          8204:                                } 
1.227     brouard  8205:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.231   ! brouard  8206:                                if(Tvard[k1][2] <=ncovcol){
        !          8207:                                        Fixed[k]= 1;
        !          8208:                                        Dummy[k]= 1;
        !          8209:                                        modell[k].maintype= VTYPE;
        !          8210:                                        modell[k].subtype= VPDD;                /*      Product time varying dummy * fixed dummy */
        !          8211:                                }else if(Tvard[k1][2] <=ncovcol+nqv){
        !          8212:                                        Fixed[k]= 1;
        !          8213:                                        Dummy[k]= 1;
        !          8214:                                        modell[k].maintype= VTYPE;
        !          8215:                                        modell[k].subtype= VPDQ;                /*      Product time varying dummy * fixed quantitative */
        !          8216:                                }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
        !          8217:                                        Fixed[k]= 1;
        !          8218:                                        Dummy[k]= 0;
        !          8219:                                        modell[k].maintype= VTYPE;
        !          8220:                                        modell[k].subtype= VPDD;                /*      Product time varying dummy * time varying dummy */
        !          8221:                                }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
        !          8222:                                        Fixed[k]= 1;
        !          8223:                                        Dummy[k]= 1;
        !          8224:                                        modell[k].maintype= VTYPE;
        !          8225:                                        modell[k].subtype= VPDQ;                /*      Product time varying dummy * time varying quantitative */
        !          8226:                                } 
1.227     brouard  8227:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.231   ! brouard  8228:                                if(Tvard[k1][2] <=ncovcol){
        !          8229:                                        Fixed[k]= 1;
        !          8230:                                        Dummy[k]= 1;
        !          8231:                                        modell[k].maintype= VTYPE;
        !          8232:                                        modell[k].subtype= VPDQ;                /*      Product time varying quantitative * fixed dummy */
        !          8233:                                }else if(Tvard[k1][2] <=ncovcol+nqv){
        !          8234:                                        Fixed[k]= 1;
        !          8235:                                        Dummy[k]= 1;
        !          8236:                                        modell[k].maintype= VTYPE;
        !          8237:                                        modell[k].subtype= VPQQ;                /*      Product time varying quantitative * fixed quantitative */
        !          8238:                                }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
        !          8239:                                        Fixed[k]= 1;
        !          8240:                                        Dummy[k]= 1;
        !          8241:                                        modell[k].maintype= VTYPE;
        !          8242:                                        modell[k].subtype= VPDQ;                /*      Product time varying quantitative * time varying dummy */
        !          8243:                                }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
        !          8244:                                        Fixed[k]= 1;
        !          8245:                                        Dummy[k]= 1;
        !          8246:                                        modell[k].maintype= VTYPE;
        !          8247:                                        modell[k].subtype= VPQQ;                /*      Product time varying quantitative * time varying quantitative */
        !          8248:                                } 
1.227     brouard  8249:       }else{
1.231   ! brouard  8250:                                printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
        !          8251:                                fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
1.226     brouard  8252:       } /* end k1 */
1.225     brouard  8253:     }else{
1.226     brouard  8254:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   8255:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  8256:     }
1.227     brouard  8257:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231   ! brouard  8258:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  8259:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   8260:   }
                   8261:   /* Searching for doublons in the model */
                   8262:   for(k1=1; k1<= cptcovt;k1++){
                   8263:     for(k2=1; k2 <k1;k2++){
                   8264:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.231   ! brouard  8265:                                if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
        !          8266:                                        if(Tvar[k1]==Tvar[k2]){
        !          8267:                                                printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
        !          8268:                                                fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
        !          8269:                                                return(1);
        !          8270:                                        }
        !          8271:                                }else if (Typevar[k1] ==2){
        !          8272:                                        k3=Tposprod[k1];
        !          8273:                                        k4=Tposprod[k2];
        !          8274:                                        if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
        !          8275:                                                printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
        !          8276:                                                fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
        !          8277:                                                return(1);
        !          8278:                                        }
        !          8279:                                }
1.227     brouard  8280:       }
                   8281:     }
1.225     brouard  8282:   }
                   8283:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   8284:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.137     brouard  8285:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  8286:   /*endread:*/
1.225     brouard  8287:   printf("Exiting decodemodel: ");
                   8288:   return (1);
1.136     brouard  8289: }
                   8290: 
1.169     brouard  8291: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.136     brouard  8292: {
                   8293:   int i, m;
1.218     brouard  8294:   int firstone=0;
                   8295:   
1.136     brouard  8296:   for (i=1; i<=imx; i++) {
                   8297:     for(m=2; (m<= maxwav); m++) {
                   8298:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   8299:        anint[m][i]=9999;
1.216     brouard  8300:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   8301:          s[m][i]=-1;
1.136     brouard  8302:       }
                   8303:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.169     brouard  8304:        *nberr = *nberr + 1;
1.218     brouard  8305:        if(firstone == 0){
                   8306:          firstone=1;
                   8307:        printf("Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\nOther similar cases in log file\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
                   8308:        }
                   8309:        fprintf(ficlog,"Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
1.136     brouard  8310:        s[m][i]=-1;
                   8311:       }
                   8312:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  8313:        (*nberr)++;
1.136     brouard  8314:        printf("Error! Month of death of individual %ld on line %d was unknown %2d, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,(int)moisdc[i]); 
                   8315:        fprintf(ficlog,"Error! Month of death of individual %ld on line %d was unknown %f, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,moisdc[i]); 
                   8316:        s[m][i]=-1; /* We prefer to skip it (and to skip it in version 0.8a1 too */
                   8317:       }
                   8318:     }
                   8319:   }
                   8320: 
                   8321:   for (i=1; i<=imx; i++)  {
                   8322:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   8323:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  8324:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  8325:        if (s[m][i] >= nlstate+1) {
1.169     brouard  8326:          if(agedc[i]>0){
                   8327:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  8328:              agev[m][i]=agedc[i];
1.214     brouard  8329:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  8330:            }else {
1.136     brouard  8331:              if ((int)andc[i]!=9999){
                   8332:                nbwarn++;
                   8333:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   8334:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   8335:                agev[m][i]=-1;
                   8336:              }
                   8337:            }
1.169     brouard  8338:          } /* agedc > 0 */
1.214     brouard  8339:        } /* end if */
1.136     brouard  8340:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   8341:                                 years but with the precision of a month */
                   8342:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   8343:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   8344:            agev[m][i]=1;
                   8345:          else if(agev[m][i] < *agemin){ 
                   8346:            *agemin=agev[m][i];
                   8347:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   8348:          }
                   8349:          else if(agev[m][i] >*agemax){
                   8350:            *agemax=agev[m][i];
1.156     brouard  8351:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  8352:          }
                   8353:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   8354:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  8355:        } /* en if 9*/
1.136     brouard  8356:        else { /* =9 */
1.214     brouard  8357:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  8358:          agev[m][i]=1;
                   8359:          s[m][i]=-1;
                   8360:        }
                   8361:       }
1.214     brouard  8362:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  8363:        agev[m][i]=1;
1.214     brouard  8364:       else{
                   8365:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   8366:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   8367:        agev[m][i]=0;
                   8368:       }
                   8369:     } /* End for lastpass */
                   8370:   }
1.136     brouard  8371:     
                   8372:   for (i=1; i<=imx; i++)  {
                   8373:     for(m=firstpass; (m<=lastpass); m++){
                   8374:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  8375:        (*nberr)++;
1.136     brouard  8376:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   8377:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   8378:        return 1;
                   8379:       }
                   8380:     }
                   8381:   }
                   8382: 
                   8383:   /*for (i=1; i<=imx; i++){
                   8384:   for (m=firstpass; (m<lastpass); m++){
                   8385:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   8386: }
                   8387: 
                   8388: }*/
                   8389: 
                   8390: 
1.139     brouard  8391:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   8392:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  8393: 
                   8394:   return (0);
1.164     brouard  8395:  /* endread:*/
1.136     brouard  8396:     printf("Exiting calandcheckages: ");
                   8397:     return (1);
                   8398: }
                   8399: 
1.172     brouard  8400: #if defined(_MSC_VER)
                   8401: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   8402: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   8403: //#include "stdafx.h"
                   8404: //#include <stdio.h>
                   8405: //#include <tchar.h>
                   8406: //#include <windows.h>
                   8407: //#include <iostream>
                   8408: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   8409: 
                   8410: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   8411: 
                   8412: BOOL IsWow64()
                   8413: {
                   8414:        BOOL bIsWow64 = FALSE;
                   8415: 
                   8416:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   8417:        //  (HANDLE, PBOOL);
                   8418: 
                   8419:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   8420: 
                   8421:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   8422:        const char funcName[] = "IsWow64Process";
                   8423:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   8424:                GetProcAddress(module, funcName);
                   8425: 
                   8426:        if (NULL != fnIsWow64Process)
                   8427:        {
                   8428:                if (!fnIsWow64Process(GetCurrentProcess(),
                   8429:                        &bIsWow64))
                   8430:                        //throw std::exception("Unknown error");
                   8431:                        printf("Unknown error\n");
                   8432:        }
                   8433:        return bIsWow64 != FALSE;
                   8434: }
                   8435: #endif
1.177     brouard  8436: 
1.191     brouard  8437: void syscompilerinfo(int logged)
1.167     brouard  8438:  {
                   8439:    /* #include "syscompilerinfo.h"*/
1.185     brouard  8440:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   8441:    /* /GS /W3 /Gy
                   8442:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   8443:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   8444:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  8445:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   8446:    */ 
                   8447:    /* 64 bits */
1.185     brouard  8448:    /*
                   8449:      /GS /W3 /Gy
                   8450:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   8451:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   8452:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   8453:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   8454:    /* Optimization are useless and O3 is slower than O2 */
                   8455:    /*
                   8456:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   8457:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   8458:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   8459:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   8460:    */
1.186     brouard  8461:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  8462:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   8463:       /PDB:"visual studio
                   8464:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   8465:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   8466:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   8467:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   8468:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   8469:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   8470:       uiAccess='false'"
                   8471:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   8472:       /NOLOGO /TLBID:1
                   8473:    */
1.177     brouard  8474: #if defined __INTEL_COMPILER
1.178     brouard  8475: #if defined(__GNUC__)
                   8476:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   8477: #endif
1.177     brouard  8478: #elif defined(__GNUC__) 
1.179     brouard  8479: #ifndef  __APPLE__
1.174     brouard  8480: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  8481: #endif
1.177     brouard  8482:    struct utsname sysInfo;
1.178     brouard  8483:    int cross = CROSS;
                   8484:    if (cross){
                   8485:           printf("Cross-");
1.191     brouard  8486:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  8487:    }
1.174     brouard  8488: #endif
                   8489: 
1.171     brouard  8490: #include <stdint.h>
1.178     brouard  8491: 
1.191     brouard  8492:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  8493: #if defined(__clang__)
1.191     brouard  8494:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  8495: #endif
                   8496: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  8497:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  8498: #endif
                   8499: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  8500:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  8501: #endif
                   8502: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  8503:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  8504: #endif
                   8505: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  8506:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  8507: #endif
                   8508: #if defined(_MSC_VER)
1.191     brouard  8509:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  8510: #endif
                   8511: #if defined(__PGI)
1.191     brouard  8512:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  8513: #endif
                   8514: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  8515:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  8516: #endif
1.191     brouard  8517:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  8518:    
1.167     brouard  8519: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   8520: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   8521:     // Windows (x64 and x86)
1.191     brouard  8522:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  8523: #elif __unix__ // all unices, not all compilers
                   8524:     // Unix
1.191     brouard  8525:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  8526: #elif __linux__
                   8527:     // linux
1.191     brouard  8528:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  8529: #elif __APPLE__
1.174     brouard  8530:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  8531:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  8532: #endif
                   8533: 
                   8534: /*  __MINGW32__          */
                   8535: /*  __CYGWIN__  */
                   8536: /* __MINGW64__  */
                   8537: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   8538: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   8539: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   8540: /* _WIN64  // Defined for applications for Win64. */
                   8541: /* _M_X64 // Defined for compilations that target x64 processors. */
                   8542: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  8543: 
1.167     brouard  8544: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  8545:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  8546: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  8547:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  8548: #else
1.191     brouard  8549:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  8550: #endif
                   8551: 
1.169     brouard  8552: #if defined(__GNUC__)
                   8553: # if defined(__GNUC_PATCHLEVEL__)
                   8554: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   8555:                             + __GNUC_MINOR__ * 100 \
                   8556:                             + __GNUC_PATCHLEVEL__)
                   8557: # else
                   8558: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   8559:                             + __GNUC_MINOR__ * 100)
                   8560: # endif
1.174     brouard  8561:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  8562:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  8563: 
                   8564:    if (uname(&sysInfo) != -1) {
                   8565:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  8566:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  8567:    }
                   8568:    else
                   8569:       perror("uname() error");
1.179     brouard  8570:    //#ifndef __INTEL_COMPILER 
                   8571: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  8572:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  8573:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  8574: #endif
1.169     brouard  8575: #endif
1.172     brouard  8576: 
                   8577:    //   void main()
                   8578:    //   {
1.169     brouard  8579: #if defined(_MSC_VER)
1.174     brouard  8580:    if (IsWow64()){
1.191     brouard  8581:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   8582:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  8583:    }
                   8584:    else{
1.191     brouard  8585:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   8586:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  8587:    }
1.172     brouard  8588:    //     printf("\nPress Enter to continue...");
                   8589:    //     getchar();
                   8590:    //   }
                   8591: 
1.169     brouard  8592: #endif
                   8593:    
1.167     brouard  8594: 
1.219     brouard  8595: }
1.136     brouard  8596: 
1.219     brouard  8597: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  8598:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
                   8599:   int i, j, k, i1 ;
1.202     brouard  8600:   /* double ftolpl = 1.e-10; */
1.180     brouard  8601:   double age, agebase, agelim;
1.203     brouard  8602:   double tot;
1.180     brouard  8603: 
1.202     brouard  8604:   strcpy(filerespl,"PL_");
                   8605:   strcat(filerespl,fileresu);
                   8606:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   8607:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   8608:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   8609:   }
1.227     brouard  8610:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   8611:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  8612:   pstamp(ficrespl);
1.203     brouard  8613:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  8614:   fprintf(ficrespl,"#Age ");
                   8615:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   8616:   fprintf(ficrespl,"\n");
1.180     brouard  8617:   
1.219     brouard  8618:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  8619: 
1.219     brouard  8620:   agebase=ageminpar;
                   8621:   agelim=agemaxpar;
1.180     brouard  8622: 
1.227     brouard  8623:   /* i1=pow(2,ncoveff); */
                   8624:   i1=pow(2,cptcoveff); /* Number of dummy covariates */
1.219     brouard  8625:   if (cptcovn < 1){i1=1;}
1.180     brouard  8626: 
1.220     brouard  8627:   for(k=1; k<=i1;k++){
                   8628:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
1.180     brouard  8629:     /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
1.219     brouard  8630:     //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
1.220     brouard  8631:     /* k=k+1; */
1.219     brouard  8632:     /* to clean */
                   8633:     //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   8634:     fprintf(ficrespl,"#******");
                   8635:     printf("#******");
                   8636:     fprintf(ficlog,"#******");
1.227     brouard  8637:     for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   8638:       fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
1.219     brouard  8639:       printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8640:       fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8641:     }
                   8642:     fprintf(ficrespl,"******\n");
                   8643:     printf("******\n");
                   8644:     fprintf(ficlog,"******\n");
1.227     brouard  8645:     if(invalidvarcomb[k]){
                   8646:       printf("\nCombination (%d) ignored because no case \n",k); 
                   8647:       fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   8648:       fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
1.220     brouard  8649:                                                continue;
1.227     brouard  8650:     }
1.219     brouard  8651: 
                   8652:     fprintf(ficrespl,"#Age ");
1.227     brouard  8653:     for(j=1;j<=cptcoveff;j++) {
1.219     brouard  8654:       fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8655:     }
                   8656:     for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   8657:     fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  8658:     
1.219     brouard  8659:     for (age=agebase; age<=agelim; age++){
                   8660:       /* for (age=agebase; age<=agebase; age++){ */
                   8661:       prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k);
                   8662:       fprintf(ficrespl,"%.0f ",age );
1.227     brouard  8663:       for(j=1;j<=cptcoveff;j++)
                   8664:        fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.219     brouard  8665:       tot=0.;
                   8666:       for(i=1; i<=nlstate;i++){
1.227     brouard  8667:        tot +=  prlim[i][i];
                   8668:        fprintf(ficrespl," %.5f", prlim[i][i]);
1.219     brouard  8669:       }
                   8670:       fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   8671:     } /* Age */
                   8672:     /* was end of cptcod */
                   8673:   } /* cptcov */
                   8674:   return 0;
1.180     brouard  8675: }
                   8676: 
1.218     brouard  8677: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   8678:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   8679:        
                   8680:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   8681:    * at any age between ageminpar and agemaxpar
                   8682:         */
1.217     brouard  8683:   int i, j, k, i1 ;
                   8684:   /* double ftolpl = 1.e-10; */
                   8685:   double age, agebase, agelim;
                   8686:   double tot;
1.218     brouard  8687:   /* double ***mobaverage; */
                   8688:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  8689: 
                   8690:   strcpy(fileresplb,"PLB_");
                   8691:   strcat(fileresplb,fileresu);
                   8692:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   8693:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   8694:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   8695:   }
                   8696:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   8697:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   8698:   pstamp(ficresplb);
                   8699:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   8700:   fprintf(ficresplb,"#Age ");
                   8701:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   8702:   fprintf(ficresplb,"\n");
                   8703:   
1.218     brouard  8704:   
                   8705:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   8706:   
                   8707:   agebase=ageminpar;
                   8708:   agelim=agemaxpar;
                   8709:   
                   8710:   
1.227     brouard  8711:   i1=pow(2,cptcoveff);
1.218     brouard  8712:   if (cptcovn < 1){i1=1;}
1.227     brouard  8713:   
                   8714:   for(k=1; k<=i1;k++){ 
1.218     brouard  8715:     //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   8716:     fprintf(ficresplb,"#******");
                   8717:     printf("#******");
                   8718:     fprintf(ficlog,"#******");
1.227     brouard  8719:     for(j=1;j<=cptcoveff ;j++) {/* all covariates */
1.218     brouard  8720:       fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8721:       printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8722:       fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8723:     }
                   8724:     fprintf(ficresplb,"******\n");
                   8725:     printf("******\n");
                   8726:     fprintf(ficlog,"******\n");
1.227     brouard  8727:     if(invalidvarcomb[k]){
                   8728:       printf("\nCombination (%d) ignored because no cases \n",k); 
                   8729:       fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   8730:       fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   8731:       continue;
                   8732:     }
1.218     brouard  8733:     
                   8734:     fprintf(ficresplb,"#Age ");
1.227     brouard  8735:     for(j=1;j<=cptcoveff;j++) {
1.218     brouard  8736:       fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8737:     }
                   8738:     for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   8739:     fprintf(ficresplb,"Total Years_to_converge\n");
                   8740:     
                   8741:     
                   8742:     for (age=agebase; age<=agelim; age++){
                   8743:       /* for (age=agebase; age<=agebase; age++){ */
                   8744:       if(mobilavproj > 0){
                   8745:        /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   8746:        /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.227     brouard  8747:        bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k);
1.218     brouard  8748:       }else if (mobilavproj == 0){
1.227     brouard  8749:        printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   8750:        fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   8751:        exit(1);
1.218     brouard  8752:       }else{
1.227     brouard  8753:        /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   8754:        bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k);
1.218     brouard  8755:       }
                   8756:       fprintf(ficresplb,"%.0f ",age );
1.227     brouard  8757:       for(j=1;j<=cptcoveff;j++)
                   8758:        fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.218     brouard  8759:       tot=0.;
                   8760:       for(i=1; i<=nlstate;i++){
1.227     brouard  8761:        tot +=  bprlim[i][i];
                   8762:        fprintf(ficresplb," %.5f", bprlim[i][i]);
1.218     brouard  8763:       }
                   8764:       fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   8765:     } /* Age */
                   8766:     /* was end of cptcod */
                   8767:   } /* cptcov */
                   8768:   
                   8769:   /* hBijx(p, bage, fage); */
                   8770:   /* fclose(ficrespijb); */
                   8771:   
                   8772:   return 0;
1.217     brouard  8773: }
1.218     brouard  8774:  
1.180     brouard  8775: int hPijx(double *p, int bage, int fage){
                   8776:     /*------------- h Pij x at various ages ------------*/
                   8777: 
                   8778:   int stepsize;
                   8779:   int agelim;
                   8780:   int hstepm;
                   8781:   int nhstepm;
                   8782:   int h, i, i1, j, k;
                   8783: 
                   8784:   double agedeb;
                   8785:   double ***p3mat;
                   8786: 
1.201     brouard  8787:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  8788:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   8789:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   8790:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   8791:     }
                   8792:     printf("Computing pij: result on file '%s' \n", filerespij);
                   8793:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   8794:   
                   8795:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8796:     /*if (stepm<=24) stepsize=2;*/
                   8797: 
                   8798:     agelim=AGESUP;
                   8799:     hstepm=stepsize*YEARM; /* Every year of age */
                   8800:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  8801:                
1.180     brouard  8802:     /* hstepm=1;   aff par mois*/
                   8803:     pstamp(ficrespij);
                   8804:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  8805:     i1= pow(2,cptcoveff);
1.218     brouard  8806:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   8807:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   8808:                /*      k=k+1;  */
1.227     brouard  8809:     for (k=1; k <= (int) pow(2,cptcoveff); k++){
1.183     brouard  8810:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  8811:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  8812:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.183     brouard  8813:       fprintf(ficrespij,"******\n");
                   8814:       
                   8815:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   8816:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   8817:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   8818:        
                   8819:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  8820:        
1.183     brouard  8821:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8822:        oldm=oldms;savm=savms;
                   8823:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
                   8824:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   8825:        for(i=1; i<=nlstate;i++)
                   8826:          for(j=1; j<=nlstate+ndeath;j++)
                   8827:            fprintf(ficrespij," %1d-%1d",i,j);
                   8828:        fprintf(ficrespij,"\n");
                   8829:        for (h=0; h<=nhstepm; h++){
                   8830:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   8831:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  8832:          for(i=1; i<=nlstate;i++)
                   8833:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  8834:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  8835:          fprintf(ficrespij,"\n");
                   8836:        }
1.183     brouard  8837:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8838:        fprintf(ficrespij,"\n");
                   8839:       }
1.180     brouard  8840:       /*}*/
                   8841:     }
1.218     brouard  8842:     return 0;
1.180     brouard  8843: }
1.218     brouard  8844:  
                   8845:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  8846:     /*------------- h Bij x at various ages ------------*/
                   8847: 
                   8848:   int stepsize;
1.218     brouard  8849:   /* int agelim; */
                   8850:        int ageminl;
1.217     brouard  8851:   int hstepm;
                   8852:   int nhstepm;
                   8853:   int h, i, i1, j, k;
1.218     brouard  8854:        
1.217     brouard  8855:   double agedeb;
                   8856:   double ***p3mat;
1.218     brouard  8857:        
                   8858:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   8859:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   8860:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   8861:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   8862:   }
                   8863:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   8864:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   8865:   
                   8866:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8867:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  8868:   
1.218     brouard  8869:   /* agelim=AGESUP; */
                   8870:   ageminl=30;
                   8871:   hstepm=stepsize*YEARM; /* Every year of age */
                   8872:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   8873:   
                   8874:   /* hstepm=1;   aff par mois*/
                   8875:   pstamp(ficrespijb);
                   8876:   fprintf(ficrespijb,"#****** h Pij x Back Probability to be in state i at age x-h being in j at x ");
1.227     brouard  8877:   i1= pow(2,cptcoveff);
1.218     brouard  8878:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   8879:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   8880:   /*   k=k+1;  */
1.227     brouard  8881:   for (k=1; k <= (int) pow(2,cptcoveff); k++){
1.218     brouard  8882:     fprintf(ficrespijb,"\n#****** ");
1.227     brouard  8883:     for(j=1;j<=cptcoveff;j++)
1.218     brouard  8884:       fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8885:     fprintf(ficrespijb,"******\n");
1.222     brouard  8886:     if(invalidvarcomb[k]){
                   8887:       fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   8888:       continue;
                   8889:     }
1.218     brouard  8890:     
                   8891:     /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   8892:     for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   8893:       /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   8894:       nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   8895:       nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   8896:       
                   8897:       /*         nhstepm=nhstepm*YEARM; aff par mois*/
                   8898:       
                   8899:       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8900:       /* oldm=oldms;savm=savms; */
                   8901:       /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8902:       hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k);
                   8903:       /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
                   8904:       fprintf(ficrespijb,"# Cov Agex agex-h hpijx with i,j=");
                   8905:       for(i=1; i<=nlstate;i++)
                   8906:        for(j=1; j<=nlstate+ndeath;j++)
                   8907:          fprintf(ficrespijb," %1d-%1d",i,j);
                   8908:       fprintf(ficrespijb,"\n");
                   8909:       for (h=0; h<=nhstepm; h++){
                   8910:        /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   8911:        fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   8912:        /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
1.217     brouard  8913:        for(i=1; i<=nlstate;i++)
                   8914:          for(j=1; j<=nlstate+ndeath;j++)
1.218     brouard  8915:            fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
1.217     brouard  8916:        fprintf(ficrespijb,"\n");
                   8917:       }
1.218     brouard  8918:       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8919:       fprintf(ficrespijb,"\n");
1.217     brouard  8920:     }
1.218     brouard  8921:     /*}*/
                   8922:   }
                   8923:   return 0;
                   8924:  } /*  hBijx */
1.217     brouard  8925: 
1.180     brouard  8926: 
1.136     brouard  8927: /***********************************************/
                   8928: /**************** Main Program *****************/
                   8929: /***********************************************/
                   8930: 
                   8931: int main(int argc, char *argv[])
                   8932: {
                   8933: #ifdef GSL
                   8934:   const gsl_multimin_fminimizer_type *T;
                   8935:   size_t iteri = 0, it;
                   8936:   int rval = GSL_CONTINUE;
                   8937:   int status = GSL_SUCCESS;
                   8938:   double ssval;
                   8939: #endif
                   8940:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  8941:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  8942:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  8943:   int jj, ll, li, lj, lk;
1.136     brouard  8944:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  8945:   int num_filled;
1.136     brouard  8946:   int itimes;
                   8947:   int NDIM=2;
                   8948:   int vpopbased=0;
                   8949: 
1.164     brouard  8950:   char ca[32], cb[32];
1.136     brouard  8951:   /*  FILE *fichtm; *//* Html File */
                   8952:   /* FILE *ficgp;*/ /*Gnuplot File */
                   8953:   struct stat info;
1.191     brouard  8954:   double agedeb=0.;
1.194     brouard  8955: 
                   8956:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  8957:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  8958: 
1.165     brouard  8959:   double fret;
1.191     brouard  8960:   double dum=0.; /* Dummy variable */
1.136     brouard  8961:   double ***p3mat;
1.218     brouard  8962:   /* double ***mobaverage; */
1.164     brouard  8963: 
                   8964:   char line[MAXLINE];
1.197     brouard  8965:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   8966: 
                   8967:   char model[MAXLINE], modeltemp[MAXLINE];
1.230     brouard  8968:   char resultline[MAXLINE];
                   8969:   
1.136     brouard  8970:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  8971:   char *tok, *val; /* pathtot */
1.136     brouard  8972:   int firstobs=1, lastobs=10;
1.195     brouard  8973:   int c,  h , cpt, c2;
1.191     brouard  8974:   int jl=0;
                   8975:   int i1, j1, jk, stepsize=0;
1.194     brouard  8976:   int count=0;
                   8977: 
1.164     brouard  8978:   int *tab; 
1.136     brouard  8979:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  8980:   int backcast=0;
1.136     brouard  8981:   int mobilav=0,popforecast=0;
1.191     brouard  8982:   int hstepm=0, nhstepm=0;
1.136     brouard  8983:   int agemortsup;
                   8984:   float  sumlpop=0.;
                   8985:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   8986:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   8987: 
1.191     brouard  8988:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  8989:   double ftolpl=FTOL;
                   8990:   double **prlim;
1.217     brouard  8991:   double **bprlim;
1.136     brouard  8992:   double ***param; /* Matrix of parameters */
                   8993:   double  *p;
                   8994:   double **matcov; /* Matrix of covariance */
1.203     brouard  8995:   double **hess; /* Hessian matrix */
1.136     brouard  8996:   double ***delti3; /* Scale */
                   8997:   double *delti; /* Scale */
                   8998:   double ***eij, ***vareij;
                   8999:   double **varpl; /* Variances of prevalence limits by age */
                   9000:   double *epj, vepp;
1.164     brouard  9001: 
1.136     brouard  9002:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  9003:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   9004: 
1.136     brouard  9005:   double **ximort;
1.145     brouard  9006:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  9007:   int *dcwave;
                   9008: 
1.164     brouard  9009:   char z[1]="c";
1.136     brouard  9010: 
                   9011:   /*char  *strt;*/
                   9012:   char strtend[80];
1.126     brouard  9013: 
1.164     brouard  9014: 
1.126     brouard  9015: /*   setlocale (LC_ALL, ""); */
                   9016: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   9017: /*   textdomain (PACKAGE); */
                   9018: /*   setlocale (LC_CTYPE, ""); */
                   9019: /*   setlocale (LC_MESSAGES, ""); */
                   9020: 
                   9021:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  9022:   rstart_time = time(NULL);  
                   9023:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   9024:   start_time = *localtime(&rstart_time);
1.126     brouard  9025:   curr_time=start_time;
1.157     brouard  9026:   /*tml = *localtime(&start_time.tm_sec);*/
                   9027:   /* strcpy(strstart,asctime(&tml)); */
                   9028:   strcpy(strstart,asctime(&start_time));
1.126     brouard  9029: 
                   9030: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  9031: /*  tp.tm_sec = tp.tm_sec +86400; */
                   9032: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  9033: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   9034: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   9035: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  9036: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  9037: /*   strt=asctime(&tmg); */
                   9038: /*   printf("Time(after) =%s",strstart);  */
                   9039: /*  (void) time (&time_value);
                   9040: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   9041: *  tm = *localtime(&time_value);
                   9042: *  strstart=asctime(&tm);
                   9043: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   9044: */
                   9045: 
                   9046:   nberr=0; /* Number of errors and warnings */
                   9047:   nbwarn=0;
1.184     brouard  9048: #ifdef WIN32
                   9049:   _getcwd(pathcd, size);
                   9050: #else
1.126     brouard  9051:   getcwd(pathcd, size);
1.184     brouard  9052: #endif
1.191     brouard  9053:   syscompilerinfo(0);
1.196     brouard  9054:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  9055:   if(argc <=1){
                   9056:     printf("\nEnter the parameter file name: ");
1.205     brouard  9057:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   9058:       printf("ERROR Empty parameter file name\n");
                   9059:       goto end;
                   9060:     }
1.126     brouard  9061:     i=strlen(pathr);
                   9062:     if(pathr[i-1]=='\n')
                   9063:       pathr[i-1]='\0';
1.156     brouard  9064:     i=strlen(pathr);
1.205     brouard  9065:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  9066:       pathr[i-1]='\0';
1.205     brouard  9067:     }
                   9068:     i=strlen(pathr);
                   9069:     if( i==0 ){
                   9070:       printf("ERROR Empty parameter file name\n");
                   9071:       goto end;
                   9072:     }
                   9073:     for (tok = pathr; tok != NULL; ){
1.126     brouard  9074:       printf("Pathr |%s|\n",pathr);
                   9075:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   9076:       printf("val= |%s| pathr=%s\n",val,pathr);
                   9077:       strcpy (pathtot, val);
                   9078:       if(pathr[0] == '\0') break; /* Dirty */
                   9079:     }
                   9080:   }
                   9081:   else{
                   9082:     strcpy(pathtot,argv[1]);
                   9083:   }
                   9084:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   9085:   /*cygwin_split_path(pathtot,path,optionfile);
                   9086:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   9087:   /* cutv(path,optionfile,pathtot,'\\');*/
                   9088: 
                   9089:   /* Split argv[0], imach program to get pathimach */
                   9090:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   9091:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9092:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9093:  /*   strcpy(pathimach,argv[0]); */
                   9094:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   9095:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   9096:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  9097: #ifdef WIN32
                   9098:   _chdir(path); /* Can be a relative path */
                   9099:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   9100: #else
1.126     brouard  9101:   chdir(path); /* Can be a relative path */
1.184     brouard  9102:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   9103: #endif
                   9104:   printf("Current directory %s!\n",pathcd);
1.126     brouard  9105:   strcpy(command,"mkdir ");
                   9106:   strcat(command,optionfilefiname);
                   9107:   if((outcmd=system(command)) != 0){
1.169     brouard  9108:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  9109:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   9110:     /* fclose(ficlog); */
                   9111: /*     exit(1); */
                   9112:   }
                   9113: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   9114: /*     perror("mkdir"); */
                   9115: /*   } */
                   9116: 
                   9117:   /*-------- arguments in the command line --------*/
                   9118: 
1.186     brouard  9119:   /* Main Log file */
1.126     brouard  9120:   strcat(filelog, optionfilefiname);
                   9121:   strcat(filelog,".log");    /* */
                   9122:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   9123:     printf("Problem with logfile %s\n",filelog);
                   9124:     goto end;
                   9125:   }
                   9126:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  9127:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  9128:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   9129:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   9130:  path=%s \n\
                   9131:  optionfile=%s\n\
                   9132:  optionfilext=%s\n\
1.156     brouard  9133:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  9134: 
1.197     brouard  9135:   syscompilerinfo(1);
1.167     brouard  9136: 
1.126     brouard  9137:   printf("Local time (at start):%s",strstart);
                   9138:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   9139:   fflush(ficlog);
                   9140: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  9141: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  9142: 
                   9143:   /* */
                   9144:   strcpy(fileres,"r");
                   9145:   strcat(fileres, optionfilefiname);
1.201     brouard  9146:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  9147:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  9148:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  9149: 
1.186     brouard  9150:   /* Main ---------arguments file --------*/
1.126     brouard  9151: 
                   9152:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  9153:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   9154:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  9155:     fflush(ficlog);
1.149     brouard  9156:     /* goto end; */
                   9157:     exit(70); 
1.126     brouard  9158:   }
                   9159: 
                   9160: 
                   9161: 
                   9162:   strcpy(filereso,"o");
1.201     brouard  9163:   strcat(filereso,fileresu);
1.126     brouard  9164:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   9165:     printf("Problem with Output resultfile: %s\n", filereso);
                   9166:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   9167:     fflush(ficlog);
                   9168:     goto end;
                   9169:   }
                   9170: 
                   9171:   /* Reads comments: lines beginning with '#' */
                   9172:   numlinepar=0;
1.197     brouard  9173: 
                   9174:     /* First parameter line */
                   9175:   while(fgets(line, MAXLINE, ficpar)) {
                   9176:     /* If line starts with a # it is a comment */
                   9177:     if (line[0] == '#') {
                   9178:       numlinepar++;
                   9179:       fputs(line,stdout);
                   9180:       fputs(line,ficparo);
                   9181:       fputs(line,ficlog);
                   9182:       continue;
                   9183:     }else
                   9184:       break;
                   9185:   }
                   9186:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   9187:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   9188:     if (num_filled != 5) {
                   9189:       printf("Should be 5 parameters\n");
                   9190:     }
1.126     brouard  9191:     numlinepar++;
1.197     brouard  9192:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   9193:   }
                   9194:   /* Second parameter line */
                   9195:   while(fgets(line, MAXLINE, ficpar)) {
                   9196:     /* If line starts with a # it is a comment */
                   9197:     if (line[0] == '#') {
                   9198:       numlinepar++;
                   9199:       fputs(line,stdout);
                   9200:       fputs(line,ficparo);
                   9201:       fputs(line,ficlog);
                   9202:       continue;
                   9203:     }else
                   9204:       break;
                   9205:   }
1.223     brouard  9206:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   9207:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   9208:     if (num_filled != 11) {
                   9209:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  9210:       printf("but line=%s\n",line);
1.197     brouard  9211:     }
1.223     brouard  9212:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  9213:   }
1.203     brouard  9214:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  9215:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  9216:   /* Third parameter line */
                   9217:   while(fgets(line, MAXLINE, ficpar)) {
                   9218:     /* If line starts with a # it is a comment */
                   9219:     if (line[0] == '#') {
                   9220:       numlinepar++;
                   9221:       fputs(line,stdout);
                   9222:       fputs(line,ficparo);
                   9223:       fputs(line,ficlog);
                   9224:       continue;
                   9225:     }else
                   9226:       break;
                   9227:   }
1.201     brouard  9228:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
                   9229:     if (num_filled == 0)
                   9230:             model[0]='\0';
                   9231:     else if (num_filled != 1){
1.197     brouard  9232:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   9233:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   9234:       model[0]='\0';
                   9235:       goto end;
                   9236:     }
                   9237:     else{
                   9238:       if (model[0]=='+'){
                   9239:        for(i=1; i<=strlen(model);i++)
                   9240:          modeltemp[i-1]=model[i];
1.201     brouard  9241:        strcpy(model,modeltemp); 
1.197     brouard  9242:       }
                   9243:     }
1.199     brouard  9244:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  9245:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  9246:   }
                   9247:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   9248:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   9249:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  9250:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   9251:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  9252:   fflush(ficlog);
1.190     brouard  9253:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   9254:   if(model[0]=='#'){
1.187     brouard  9255:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   9256:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   9257:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   9258:     if(mle != -1){
                   9259:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   9260:       exit(1);
                   9261:     }
                   9262:   }
1.126     brouard  9263:   while((c=getc(ficpar))=='#' && c!= EOF){
                   9264:     ungetc(c,ficpar);
                   9265:     fgets(line, MAXLINE, ficpar);
                   9266:     numlinepar++;
1.195     brouard  9267:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   9268:       z[0]=line[1];
                   9269:     }
                   9270:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  9271:     fputs(line, stdout);
                   9272:     //puts(line);
1.126     brouard  9273:     fputs(line,ficparo);
                   9274:     fputs(line,ficlog);
                   9275:   }
                   9276:   ungetc(c,ficpar);
                   9277: 
                   9278:    
1.145     brouard  9279:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.225     brouard  9280:   coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
                   9281:   cotvar=ma3x(1,maxwav,1,ntv,1,n);  /**< Time varying covariate */
                   9282:   cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
1.136     brouard  9283:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   9284:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   9285:      v1+v2*age+v2*v3 makes cptcovn = 3
                   9286:   */
                   9287:   if (strlen(model)>1) 
1.187     brouard  9288:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  9289:   else
1.187     brouard  9290:     ncovmodel=2; /* Constant and age */
1.133     brouard  9291:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   9292:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  9293:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   9294:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   9295:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   9296:     fflush(stdout);
                   9297:     fclose (ficlog);
                   9298:     goto end;
                   9299:   }
1.126     brouard  9300:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   9301:   delti=delti3[1][1];
                   9302:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   9303:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
                   9304:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  9305:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   9306:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  9307:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   9308:     fclose (ficparo);
                   9309:     fclose (ficlog);
                   9310:     goto end;
                   9311:     exit(0);
1.220     brouard  9312:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  9313:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  9314:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   9315:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  9316:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   9317:     matcov=matrix(1,npar,1,npar);
1.203     brouard  9318:     hess=matrix(1,npar,1,npar);
1.220     brouard  9319:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  9320:     /* Read guessed parameters */
1.126     brouard  9321:     /* Reads comments: lines beginning with '#' */
                   9322:     while((c=getc(ficpar))=='#' && c!= EOF){
                   9323:       ungetc(c,ficpar);
                   9324:       fgets(line, MAXLINE, ficpar);
                   9325:       numlinepar++;
1.141     brouard  9326:       fputs(line,stdout);
1.126     brouard  9327:       fputs(line,ficparo);
                   9328:       fputs(line,ficlog);
                   9329:     }
                   9330:     ungetc(c,ficpar);
                   9331:     
                   9332:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   9333:     for(i=1; i <=nlstate; i++){
1.220     brouard  9334:                        j=0;
1.126     brouard  9335:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.220     brouard  9336:                                if(jj==i) continue;
                   9337:                                j++;
                   9338:                                fscanf(ficpar,"%1d%1d",&i1,&j1);
                   9339:                                if ((i1 != i) || (j1 != jj)){
                   9340:                                        printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  9341: It might be a problem of design; if ncovcol and the model are correct\n \
                   9342: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.220     brouard  9343:                                        exit(1);
                   9344:                                }
                   9345:                                fprintf(ficparo,"%1d%1d",i1,j1);
                   9346:                                if(mle==1)
                   9347:                                        printf("%1d%1d",i,jj);
                   9348:                                fprintf(ficlog,"%1d%1d",i,jj);
                   9349:                                for(k=1; k<=ncovmodel;k++){
                   9350:                                        fscanf(ficpar," %lf",&param[i][j][k]);
                   9351:                                        if(mle==1){
                   9352:                                                printf(" %lf",param[i][j][k]);
                   9353:                                                fprintf(ficlog," %lf",param[i][j][k]);
                   9354:                                        }
                   9355:                                        else
                   9356:                                                fprintf(ficlog," %lf",param[i][j][k]);
                   9357:                                        fprintf(ficparo," %lf",param[i][j][k]);
                   9358:                                }
                   9359:                                fscanf(ficpar,"\n");
                   9360:                                numlinepar++;
                   9361:                                if(mle==1)
                   9362:                                        printf("\n");
                   9363:                                fprintf(ficlog,"\n");
                   9364:                                fprintf(ficparo,"\n");
1.126     brouard  9365:       }
                   9366:     }  
                   9367:     fflush(ficlog);
                   9368: 
1.145     brouard  9369:     /* Reads scales values */
1.126     brouard  9370:     p=param[1][1];
                   9371:     
                   9372:     /* Reads comments: lines beginning with '#' */
                   9373:     while((c=getc(ficpar))=='#' && c!= EOF){
                   9374:       ungetc(c,ficpar);
                   9375:       fgets(line, MAXLINE, ficpar);
                   9376:       numlinepar++;
1.141     brouard  9377:       fputs(line,stdout);
1.126     brouard  9378:       fputs(line,ficparo);
                   9379:       fputs(line,ficlog);
                   9380:     }
                   9381:     ungetc(c,ficpar);
                   9382: 
                   9383:     for(i=1; i <=nlstate; i++){
                   9384:       for(j=1; j <=nlstate+ndeath-1; j++){
1.220     brouard  9385:                                fscanf(ficpar,"%1d%1d",&i1,&j1);
                   9386:                                if ( (i1-i) * (j1-j) != 0){
                   9387:                                        printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   9388:                                        exit(1);
                   9389:                                }
                   9390:                                printf("%1d%1d",i,j);
                   9391:                                fprintf(ficparo,"%1d%1d",i1,j1);
                   9392:                                fprintf(ficlog,"%1d%1d",i1,j1);
                   9393:                                for(k=1; k<=ncovmodel;k++){
                   9394:                                        fscanf(ficpar,"%le",&delti3[i][j][k]);
                   9395:                                        printf(" %le",delti3[i][j][k]);
                   9396:                                        fprintf(ficparo," %le",delti3[i][j][k]);
                   9397:                                        fprintf(ficlog," %le",delti3[i][j][k]);
                   9398:                                }
                   9399:                                fscanf(ficpar,"\n");
                   9400:                                numlinepar++;
                   9401:                                printf("\n");
                   9402:                                fprintf(ficparo,"\n");
                   9403:                                fprintf(ficlog,"\n");
1.126     brouard  9404:       }
                   9405:     }
                   9406:     fflush(ficlog);
1.220     brouard  9407:                
1.145     brouard  9408:     /* Reads covariance matrix */
1.126     brouard  9409:     delti=delti3[1][1];
1.220     brouard  9410:                
                   9411:                
1.126     brouard  9412:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  9413:                
1.126     brouard  9414:     /* Reads comments: lines beginning with '#' */
                   9415:     while((c=getc(ficpar))=='#' && c!= EOF){
                   9416:       ungetc(c,ficpar);
                   9417:       fgets(line, MAXLINE, ficpar);
                   9418:       numlinepar++;
1.141     brouard  9419:       fputs(line,stdout);
1.126     brouard  9420:       fputs(line,ficparo);
                   9421:       fputs(line,ficlog);
                   9422:     }
                   9423:     ungetc(c,ficpar);
1.220     brouard  9424:                
1.126     brouard  9425:     matcov=matrix(1,npar,1,npar);
1.203     brouard  9426:     hess=matrix(1,npar,1,npar);
1.131     brouard  9427:     for(i=1; i <=npar; i++)
                   9428:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  9429:                
1.194     brouard  9430:     /* Scans npar lines */
1.126     brouard  9431:     for(i=1; i <=npar; i++){
1.226     brouard  9432:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  9433:       if(count != 3){
1.226     brouard  9434:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  9435: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   9436: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  9437:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  9438: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   9439: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  9440:        exit(1);
1.220     brouard  9441:       }else{
1.226     brouard  9442:        if(mle==1)
                   9443:          printf("%1d%1d%d",i1,j1,jk);
                   9444:       }
                   9445:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   9446:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  9447:       for(j=1; j <=i; j++){
1.226     brouard  9448:        fscanf(ficpar," %le",&matcov[i][j]);
                   9449:        if(mle==1){
                   9450:          printf(" %.5le",matcov[i][j]);
                   9451:        }
                   9452:        fprintf(ficlog," %.5le",matcov[i][j]);
                   9453:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  9454:       }
                   9455:       fscanf(ficpar,"\n");
                   9456:       numlinepar++;
                   9457:       if(mle==1)
1.220     brouard  9458:                                printf("\n");
1.126     brouard  9459:       fprintf(ficlog,"\n");
                   9460:       fprintf(ficparo,"\n");
                   9461:     }
1.194     brouard  9462:     /* End of read covariance matrix npar lines */
1.126     brouard  9463:     for(i=1; i <=npar; i++)
                   9464:       for(j=i+1;j<=npar;j++)
1.226     brouard  9465:        matcov[i][j]=matcov[j][i];
1.126     brouard  9466:     
                   9467:     if(mle==1)
                   9468:       printf("\n");
                   9469:     fprintf(ficlog,"\n");
                   9470:     
                   9471:     fflush(ficlog);
                   9472:     
                   9473:     /*-------- Rewriting parameter file ----------*/
                   9474:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   9475:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   9476:     strcat(rfileres,".");    /* */
                   9477:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   9478:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  9479:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   9480:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  9481:     }
                   9482:     fprintf(ficres,"#%s\n",version);
                   9483:   }    /* End of mle != -3 */
1.218     brouard  9484:   
1.186     brouard  9485:   /*  Main data
                   9486:    */
1.126     brouard  9487:   n= lastobs;
                   9488:   num=lvector(1,n);
                   9489:   moisnais=vector(1,n);
                   9490:   annais=vector(1,n);
                   9491:   moisdc=vector(1,n);
                   9492:   andc=vector(1,n);
1.220     brouard  9493:   weight=vector(1,n);
1.126     brouard  9494:   agedc=vector(1,n);
                   9495:   cod=ivector(1,n);
1.220     brouard  9496:   for(i=1;i<=n;i++){
                   9497:                num[i]=0;
                   9498:                moisnais[i]=0;
                   9499:                annais[i]=0;
                   9500:                moisdc[i]=0;
                   9501:                andc[i]=0;
                   9502:                agedc[i]=0;
                   9503:                cod[i]=0;
                   9504:                weight[i]=1.0; /* Equal weights, 1 by default */
                   9505:        }
1.126     brouard  9506:   mint=matrix(1,maxwav,1,n);
                   9507:   anint=matrix(1,maxwav,1,n);
1.131     brouard  9508:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  9509:   tab=ivector(1,NCOVMAX);
1.144     brouard  9510:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  9511:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  9512: 
1.136     brouard  9513:   /* Reads data from file datafile */
                   9514:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   9515:     goto end;
                   9516: 
                   9517:   /* Calculation of the number of parameters from char model */
1.137     brouard  9518:     /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
                   9519:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   9520:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   9521:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   9522:        k=1 Tvar[1]=2 (from V2)
                   9523:     */
1.231   ! brouard  9524: 
        !          9525:        Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
        !          9526:   TvarFD=ivector(1,NCOVMAX); /*  */
        !          9527:   TvarFDind=ivector(1,NCOVMAX); /*  */
        !          9528:   TvarFQ=ivector(1,NCOVMAX); /*  */
        !          9529:   TvarFQind=ivector(1,NCOVMAX); /*  */
        !          9530:   TvarVD=ivector(1,NCOVMAX); /*  */
        !          9531:   TvarVDind=ivector(1,NCOVMAX); /*  */
        !          9532:   TvarVQ=ivector(1,NCOVMAX); /*  */
        !          9533:   TvarVQind=ivector(1,NCOVMAX); /*  */
        !          9534: 
1.230     brouard  9535:   Tvalsel=vector(1,NCOVMAX); /*  */
1.226     brouard  9536:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   9537:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   9538:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  9539:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   9540:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   9541:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   9542:   */
                   9543:   /* For model-covariate k tells which data-covariate to use but
                   9544:     because this model-covariate is a construction we invent a new column
                   9545:     ncovcol + k1
                   9546:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   9547:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  9548:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   9549:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  9550:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   9551:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  9552:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  9553:   */
1.145     brouard  9554:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   9555:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  9556:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   9557:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  9558:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  9559:                         4 covariates (3 plus signs)
                   9560:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   9561:                      */  
1.230     brouard  9562:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  9563:                                * individual dummy, fixed or varying:
                   9564:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   9565:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  9566:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   9567:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   9568:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   9569:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   9570:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  9571:                                * individual quantitative, fixed or varying:
                   9572:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   9573:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   9574:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  9575: /* Main decodemodel */
                   9576: 
1.187     brouard  9577: 
1.223     brouard  9578:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  9579:     goto end;
                   9580: 
1.137     brouard  9581:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   9582:     nbwarn++;
                   9583:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   9584:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   9585:   }
1.136     brouard  9586:     /*  if(mle==1){*/
1.137     brouard  9587:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   9588:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  9589:   }
                   9590: 
                   9591:     /*-calculation of age at interview from date of interview and age at death -*/
                   9592:   agev=matrix(1,maxwav,1,imx);
                   9593: 
                   9594:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   9595:     goto end;
                   9596: 
1.126     brouard  9597: 
1.136     brouard  9598:   agegomp=(int)agemin;
                   9599:   free_vector(moisnais,1,n);
                   9600:   free_vector(annais,1,n);
1.126     brouard  9601:   /* free_matrix(mint,1,maxwav,1,n);
                   9602:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  9603:   /* free_vector(moisdc,1,n); */
                   9604:   /* free_vector(andc,1,n); */
1.145     brouard  9605:   /* */
                   9606:   
1.126     brouard  9607:   wav=ivector(1,imx);
1.214     brouard  9608:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   9609:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   9610:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   9611:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   9612:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   9613:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  9614:    
                   9615:   /* Concatenates waves */
1.214     brouard  9616:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   9617:      Death is a valid wave (if date is known).
                   9618:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   9619:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   9620:      and mw[mi+1][i]. dh depends on stepm.
                   9621:   */
                   9622: 
1.126     brouard  9623:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.145     brouard  9624:   /* */
                   9625:  
1.215     brouard  9626:   free_vector(moisdc,1,n);
                   9627:   free_vector(andc,1,n);
                   9628: 
1.126     brouard  9629:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   9630:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   9631:   ncodemax[1]=1;
1.145     brouard  9632:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  9633:   cptcoveff=0;
1.220     brouard  9634:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   9635:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  9636:   }
                   9637:   
                   9638:   ncovcombmax=pow(2,cptcoveff);
                   9639:   invalidvarcomb=ivector(1, ncovcombmax); 
                   9640:   for(i=1;i<ncovcombmax;i++)
                   9641:     invalidvarcomb[i]=0;
                   9642:   
1.211     brouard  9643:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  9644:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  9645:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  9646:   
1.200     brouard  9647:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  9648:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  9649:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  9650:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   9651:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   9652:    * (currently 0 or 1) in the data.
                   9653:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   9654:    * corresponding modality (h,j).
                   9655:    */
                   9656: 
1.145     brouard  9657:   h=0;
                   9658:   /*if (cptcovn > 0) */
1.126     brouard  9659:   m=pow(2,cptcoveff);
                   9660:  
1.144     brouard  9661:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  9662:           * For k=4 covariates, h goes from 1 to m=2**k
                   9663:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   9664:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  9665:           *     h\k   1     2     3     4
1.143     brouard  9666:           *______________________________  
                   9667:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   9668:           *     2     2     1     1     1
                   9669:           *     3 i=2 1     2     1     1
                   9670:           *     4     2     2     1     1
                   9671:           *     5 i=3 1 i=2 1     2     1
                   9672:           *     6     2     1     2     1
                   9673:           *     7 i=4 1     2     2     1
                   9674:           *     8     2     2     2     1
1.197     brouard  9675:           *     9 i=5 1 i=3 1 i=2 1     2
                   9676:           *    10     2     1     1     2
                   9677:           *    11 i=6 1     2     1     2
                   9678:           *    12     2     2     1     2
                   9679:           *    13 i=7 1 i=4 1     2     2    
                   9680:           *    14     2     1     2     2
                   9681:           *    15 i=8 1     2     2     2
                   9682:           *    16     2     2     2     2
1.143     brouard  9683:           */
1.212     brouard  9684:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  9685:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   9686:      * and the value of each covariate?
                   9687:      * V1=1, V2=1, V3=2, V4=1 ?
                   9688:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   9689:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   9690:      * In order to get the real value in the data, we use nbcode
                   9691:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   9692:      * We are keeping this crazy system in order to be able (in the future?) 
                   9693:      * to have more than 2 values (0 or 1) for a covariate.
                   9694:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   9695:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   9696:      *              bbbbbbbb
                   9697:      *              76543210     
                   9698:      *   h-1        00000101 (6-1=5)
1.219     brouard  9699:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  9700:      *           &
                   9701:      *     1        00000001 (1)
1.219     brouard  9702:      *              00000000        = 1 & ((h-1) >> (k-1))
                   9703:      *          +1= 00000001 =1 
1.211     brouard  9704:      *
                   9705:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   9706:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   9707:      *    >>k'            11
                   9708:      *          &   00000001
                   9709:      *            = 00000001
                   9710:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   9711:      * Reverse h=6 and m=16?
                   9712:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   9713:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   9714:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   9715:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   9716:      * V3=decodtabm(14,3,2**4)=2
                   9717:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   9718:      *(h-1) >> (j-1)    0011 =13 >> 2
                   9719:      *          &1 000000001
                   9720:      *           = 000000001
                   9721:      *         +1= 000000010 =2
                   9722:      *                  2211
                   9723:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   9724:      *                  V3=2
1.220     brouard  9725:                 * codtabm and decodtabm are identical
1.211     brouard  9726:      */
                   9727: 
1.145     brouard  9728: 
                   9729:  free_ivector(Ndum,-1,NCOVMAX);
                   9730: 
                   9731: 
1.126     brouard  9732:     
1.186     brouard  9733:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  9734:   strcpy(optionfilegnuplot,optionfilefiname);
                   9735:   if(mle==-3)
1.201     brouard  9736:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  9737:   strcat(optionfilegnuplot,".gp");
                   9738: 
                   9739:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   9740:     printf("Problem with file %s",optionfilegnuplot);
                   9741:   }
                   9742:   else{
1.204     brouard  9743:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  9744:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  9745:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   9746:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  9747:   }
                   9748:   /*  fclose(ficgp);*/
1.186     brouard  9749: 
                   9750: 
                   9751:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  9752: 
                   9753:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   9754:   if(mle==-3)
1.201     brouard  9755:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  9756:   strcat(optionfilehtm,".htm");
                   9757:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  9758:     printf("Problem with %s \n",optionfilehtm);
                   9759:     exit(0);
1.126     brouard  9760:   }
                   9761: 
                   9762:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   9763:   strcat(optionfilehtmcov,"-cov.htm");
                   9764:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   9765:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   9766:   }
                   9767:   else{
                   9768:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   9769: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  9770: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  9771:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   9772:   }
                   9773: 
1.213     brouard  9774:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  9775: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   9776: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  9777: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  9778: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  9779: \n\
                   9780: <hr  size=\"2\" color=\"#EC5E5E\">\
                   9781:  <ul><li><h4>Parameter files</h4>\n\
                   9782:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   9783:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   9784:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   9785:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   9786:  - Date and time at start: %s</ul>\n",\
                   9787:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   9788:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   9789:          fileres,fileres,\
                   9790:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   9791:   fflush(fichtm);
                   9792: 
                   9793:   strcpy(pathr,path);
                   9794:   strcat(pathr,optionfilefiname);
1.184     brouard  9795: #ifdef WIN32
                   9796:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   9797: #else
1.126     brouard  9798:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  9799: #endif
                   9800:          
1.126     brouard  9801:   
1.220     brouard  9802:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   9803:                 and for any valid combination of covariates
1.126     brouard  9804:      and prints on file fileres'p'. */
1.227     brouard  9805:   freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
                   9806:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  9807: 
                   9808:   fprintf(fichtm,"\n");
                   9809:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   9810: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   9811: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   9812:          imx,agemin,agemax,jmin,jmax,jmean);
                   9813:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.220     brouard  9814:        oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   9815:        newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   9816:        savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   9817:        oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  9818: 
1.126     brouard  9819:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   9820:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   9821:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   9822: 
                   9823:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  9824:   /* For mortality only */
1.126     brouard  9825:   if (mle==-3){
1.136     brouard  9826:     ximort=matrix(1,NDIM,1,NDIM); 
1.220     brouard  9827:                for(i=1;i<=NDIM;i++)
                   9828:                        for(j=1;j<=NDIM;j++)
                   9829:                                ximort[i][j]=0.;
1.186     brouard  9830:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  9831:     cens=ivector(1,n);
                   9832:     ageexmed=vector(1,n);
                   9833:     agecens=vector(1,n);
                   9834:     dcwave=ivector(1,n);
1.223     brouard  9835:                
1.126     brouard  9836:     for (i=1; i<=imx; i++){
                   9837:       dcwave[i]=-1;
                   9838:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  9839:        if (s[m][i]>nlstate) {
                   9840:          dcwave[i]=m;
                   9841:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   9842:          break;
                   9843:        }
1.126     brouard  9844:     }
1.226     brouard  9845:     
1.126     brouard  9846:     for (i=1; i<=imx; i++) {
                   9847:       if (wav[i]>0){
1.226     brouard  9848:        ageexmed[i]=agev[mw[1][i]][i];
                   9849:        j=wav[i];
                   9850:        agecens[i]=1.; 
                   9851:        
                   9852:        if (ageexmed[i]> 1 && wav[i] > 0){
                   9853:          agecens[i]=agev[mw[j][i]][i];
                   9854:          cens[i]= 1;
                   9855:        }else if (ageexmed[i]< 1) 
                   9856:          cens[i]= -1;
                   9857:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   9858:          cens[i]=0 ;
1.126     brouard  9859:       }
                   9860:       else cens[i]=-1;
                   9861:     }
                   9862:     
                   9863:     for (i=1;i<=NDIM;i++) {
                   9864:       for (j=1;j<=NDIM;j++)
1.226     brouard  9865:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  9866:     }
                   9867:     
1.145     brouard  9868:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  9869:     /*printf("%lf %lf", p[1], p[2]);*/
                   9870:     
                   9871:     
1.136     brouard  9872: #ifdef GSL
                   9873:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  9874: #else
1.126     brouard  9875:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  9876: #endif
1.201     brouard  9877:     strcpy(filerespow,"POW-MORT_"); 
                   9878:     strcat(filerespow,fileresu);
1.126     brouard  9879:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   9880:       printf("Problem with resultfile: %s\n", filerespow);
                   9881:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   9882:     }
1.136     brouard  9883: #ifdef GSL
                   9884:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  9885: #else
1.126     brouard  9886:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  9887: #endif
1.126     brouard  9888:     /*  for (i=1;i<=nlstate;i++)
                   9889:        for(j=1;j<=nlstate+ndeath;j++)
                   9890:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   9891:     */
                   9892:     fprintf(ficrespow,"\n");
1.136     brouard  9893: #ifdef GSL
                   9894:     /* gsl starts here */ 
                   9895:     T = gsl_multimin_fminimizer_nmsimplex;
                   9896:     gsl_multimin_fminimizer *sfm = NULL;
                   9897:     gsl_vector *ss, *x;
                   9898:     gsl_multimin_function minex_func;
                   9899: 
                   9900:     /* Initial vertex size vector */
                   9901:     ss = gsl_vector_alloc (NDIM);
                   9902:     
                   9903:     if (ss == NULL){
                   9904:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   9905:     }
                   9906:     /* Set all step sizes to 1 */
                   9907:     gsl_vector_set_all (ss, 0.001);
                   9908: 
                   9909:     /* Starting point */
1.126     brouard  9910:     
1.136     brouard  9911:     x = gsl_vector_alloc (NDIM);
                   9912:     
                   9913:     if (x == NULL){
                   9914:       gsl_vector_free(ss);
                   9915:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   9916:     }
                   9917:   
                   9918:     /* Initialize method and iterate */
                   9919:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  9920:     /*     gsl_vector_set(x, 0, 0.0268); */
                   9921:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  9922:     gsl_vector_set(x, 0, p[1]);
                   9923:     gsl_vector_set(x, 1, p[2]);
                   9924: 
                   9925:     minex_func.f = &gompertz_f;
                   9926:     minex_func.n = NDIM;
                   9927:     minex_func.params = (void *)&p; /* ??? */
                   9928:     
                   9929:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   9930:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   9931:     
                   9932:     printf("Iterations beginning .....\n\n");
                   9933:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   9934: 
                   9935:     iteri=0;
                   9936:     while (rval == GSL_CONTINUE){
                   9937:       iteri++;
                   9938:       status = gsl_multimin_fminimizer_iterate(sfm);
                   9939:       
                   9940:       if (status) printf("error: %s\n", gsl_strerror (status));
                   9941:       fflush(0);
                   9942:       
                   9943:       if (status) 
                   9944:         break;
                   9945:       
                   9946:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   9947:       ssval = gsl_multimin_fminimizer_size (sfm);
                   9948:       
                   9949:       if (rval == GSL_SUCCESS)
                   9950:         printf ("converged to a local maximum at\n");
                   9951:       
                   9952:       printf("%5d ", iteri);
                   9953:       for (it = 0; it < NDIM; it++){
                   9954:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   9955:       }
                   9956:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   9957:     }
                   9958:     
                   9959:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   9960:     
                   9961:     gsl_vector_free(x); /* initial values */
                   9962:     gsl_vector_free(ss); /* inital step size */
                   9963:     for (it=0; it<NDIM; it++){
                   9964:       p[it+1]=gsl_vector_get(sfm->x,it);
                   9965:       fprintf(ficrespow," %.12lf", p[it]);
                   9966:     }
                   9967:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   9968: #endif
                   9969: #ifdef POWELL
                   9970:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   9971: #endif  
1.126     brouard  9972:     fclose(ficrespow);
                   9973:     
1.203     brouard  9974:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  9975: 
                   9976:     for(i=1; i <=NDIM; i++)
                   9977:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  9978:                                matcov[i][j]=matcov[j][i];
1.126     brouard  9979:     
                   9980:     printf("\nCovariance matrix\n ");
1.203     brouard  9981:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  9982:     for(i=1; i <=NDIM; i++) {
                   9983:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  9984:                                printf("%f ",matcov[i][j]);
                   9985:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  9986:       }
1.203     brouard  9987:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  9988:     }
                   9989:     
                   9990:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  9991:     for (i=1;i<=NDIM;i++) {
1.126     brouard  9992:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  9993:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   9994:     }
1.126     brouard  9995:     lsurv=vector(1,AGESUP);
                   9996:     lpop=vector(1,AGESUP);
                   9997:     tpop=vector(1,AGESUP);
                   9998:     lsurv[agegomp]=100000;
                   9999:     
                   10000:     for (k=agegomp;k<=AGESUP;k++) {
                   10001:       agemortsup=k;
                   10002:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   10003:     }
                   10004:     
                   10005:     for (k=agegomp;k<agemortsup;k++)
                   10006:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   10007:     
                   10008:     for (k=agegomp;k<agemortsup;k++){
                   10009:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   10010:       sumlpop=sumlpop+lpop[k];
                   10011:     }
                   10012:     
                   10013:     tpop[agegomp]=sumlpop;
                   10014:     for (k=agegomp;k<(agemortsup-3);k++){
                   10015:       /*  tpop[k+1]=2;*/
                   10016:       tpop[k+1]=tpop[k]-lpop[k];
                   10017:     }
                   10018:     
                   10019:     
                   10020:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   10021:     for (k=agegomp;k<(agemortsup-2);k++) 
                   10022:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   10023:     
                   10024:     
                   10025:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  10026:                ageminpar=50;
                   10027:                agemaxpar=100;
1.194     brouard  10028:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   10029:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10030: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10031: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   10032:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10033: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10034: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10035:     }else{
                   10036:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   10037:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  10038:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  10039:                }
1.201     brouard  10040:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  10041:                     stepm, weightopt,\
                   10042:                     model,imx,p,matcov,agemortsup);
                   10043:     
                   10044:     free_vector(lsurv,1,AGESUP);
                   10045:     free_vector(lpop,1,AGESUP);
                   10046:     free_vector(tpop,1,AGESUP);
1.220     brouard  10047:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  10048:     free_ivector(cens,1,n);
                   10049:     free_vector(agecens,1,n);
                   10050:     free_ivector(dcwave,1,n);
1.220     brouard  10051: #ifdef GSL
1.136     brouard  10052: #endif
1.186     brouard  10053:   } /* Endof if mle==-3 mortality only */
1.205     brouard  10054:   /* Standard  */
                   10055:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   10056:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10057:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  10058:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  10059:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10060:     for (k=1; k<=npar;k++)
                   10061:       printf(" %d %8.5f",k,p[k]);
                   10062:     printf("\n");
1.205     brouard  10063:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   10064:       /* mlikeli uses func not funcone */
                   10065:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   10066:     }
                   10067:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   10068:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10069:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   10070:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10071:     }
                   10072:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  10073:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10074:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10075:     for (k=1; k<=npar;k++)
                   10076:       printf(" %d %8.5f",k,p[k]);
                   10077:     printf("\n");
                   10078:     
                   10079:     /*--------- results files --------------*/
1.224     brouard  10080:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  10081:     
                   10082:     
                   10083:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10084:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10085:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10086:     for(i=1,jk=1; i <=nlstate; i++){
                   10087:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  10088:        if (k != i) {
                   10089:          printf("%d%d ",i,k);
                   10090:          fprintf(ficlog,"%d%d ",i,k);
                   10091:          fprintf(ficres,"%1d%1d ",i,k);
                   10092:          for(j=1; j <=ncovmodel; j++){
                   10093:            printf("%12.7f ",p[jk]);
                   10094:            fprintf(ficlog,"%12.7f ",p[jk]);
                   10095:            fprintf(ficres,"%12.7f ",p[jk]);
                   10096:            jk++; 
                   10097:          }
                   10098:          printf("\n");
                   10099:          fprintf(ficlog,"\n");
                   10100:          fprintf(ficres,"\n");
                   10101:        }
1.126     brouard  10102:       }
                   10103:     }
1.203     brouard  10104:     if(mle != 0){
                   10105:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  10106:       ftolhess=ftol; /* Usually correct */
1.203     brouard  10107:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   10108:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10109:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10110:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  10111:        for(k=1; k <=(nlstate+ndeath); k++){
                   10112:          if (k != i) {
                   10113:            printf("%d%d ",i,k);
                   10114:            fprintf(ficlog,"%d%d ",i,k);
                   10115:            for(j=1; j <=ncovmodel; j++){
                   10116:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10117:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10118:              jk++; 
                   10119:            }
                   10120:            printf("\n");
                   10121:            fprintf(ficlog,"\n");
                   10122:          }
                   10123:        }
1.193     brouard  10124:       }
1.203     brouard  10125:     } /* end of hesscov and Wald tests */
1.225     brouard  10126:     
1.203     brouard  10127:     /*  */
1.126     brouard  10128:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   10129:     printf("# Scales (for hessian or gradient estimation)\n");
                   10130:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   10131:     for(i=1,jk=1; i <=nlstate; i++){
                   10132:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  10133:        if (j!=i) {
                   10134:          fprintf(ficres,"%1d%1d",i,j);
                   10135:          printf("%1d%1d",i,j);
                   10136:          fprintf(ficlog,"%1d%1d",i,j);
                   10137:          for(k=1; k<=ncovmodel;k++){
                   10138:            printf(" %.5e",delti[jk]);
                   10139:            fprintf(ficlog," %.5e",delti[jk]);
                   10140:            fprintf(ficres," %.5e",delti[jk]);
                   10141:            jk++;
                   10142:          }
                   10143:          printf("\n");
                   10144:          fprintf(ficlog,"\n");
                   10145:          fprintf(ficres,"\n");
                   10146:        }
1.126     brouard  10147:       }
                   10148:     }
                   10149:     
                   10150:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  10151:     if(mle >= 1) /* To big for the screen */
1.126     brouard  10152:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   10153:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   10154:     /* # 121 Var(a12)\n\ */
                   10155:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   10156:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   10157:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   10158:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   10159:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   10160:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   10161:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   10162:     
                   10163:     
                   10164:     /* Just to have a covariance matrix which will be more understandable
                   10165:        even is we still don't want to manage dictionary of variables
                   10166:     */
                   10167:     for(itimes=1;itimes<=2;itimes++){
                   10168:       jj=0;
                   10169:       for(i=1; i <=nlstate; i++){
1.225     brouard  10170:        for(j=1; j <=nlstate+ndeath; j++){
                   10171:          if(j==i) continue;
                   10172:          for(k=1; k<=ncovmodel;k++){
                   10173:            jj++;
                   10174:            ca[0]= k+'a'-1;ca[1]='\0';
                   10175:            if(itimes==1){
                   10176:              if(mle>=1)
                   10177:                printf("#%1d%1d%d",i,j,k);
                   10178:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   10179:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   10180:            }else{
                   10181:              if(mle>=1)
                   10182:                printf("%1d%1d%d",i,j,k);
                   10183:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   10184:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   10185:            }
                   10186:            ll=0;
                   10187:            for(li=1;li <=nlstate; li++){
                   10188:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   10189:                if(lj==li) continue;
                   10190:                for(lk=1;lk<=ncovmodel;lk++){
                   10191:                  ll++;
                   10192:                  if(ll<=jj){
                   10193:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   10194:                    if(ll<jj){
                   10195:                      if(itimes==1){
                   10196:                        if(mle>=1)
                   10197:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10198:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10199:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10200:                      }else{
                   10201:                        if(mle>=1)
                   10202:                          printf(" %.5e",matcov[jj][ll]); 
                   10203:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   10204:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   10205:                      }
                   10206:                    }else{
                   10207:                      if(itimes==1){
                   10208:                        if(mle>=1)
                   10209:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   10210:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   10211:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   10212:                      }else{
                   10213:                        if(mle>=1)
                   10214:                          printf(" %.7e",matcov[jj][ll]); 
                   10215:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   10216:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   10217:                      }
                   10218:                    }
                   10219:                  }
                   10220:                } /* end lk */
                   10221:              } /* end lj */
                   10222:            } /* end li */
                   10223:            if(mle>=1)
                   10224:              printf("\n");
                   10225:            fprintf(ficlog,"\n");
                   10226:            fprintf(ficres,"\n");
                   10227:            numlinepar++;
                   10228:          } /* end k*/
                   10229:        } /*end j */
1.126     brouard  10230:       } /* end i */
                   10231:     } /* end itimes */
                   10232:     
                   10233:     fflush(ficlog);
                   10234:     fflush(ficres);
1.225     brouard  10235:     while(fgets(line, MAXLINE, ficpar)) {
                   10236:       /* If line starts with a # it is a comment */
                   10237:       if (line[0] == '#') {
                   10238:        numlinepar++;
                   10239:        fputs(line,stdout);
                   10240:        fputs(line,ficparo);
                   10241:        fputs(line,ficlog);
                   10242:        continue;
                   10243:       }else
                   10244:        break;
                   10245:     }
                   10246:     
1.209     brouard  10247:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   10248:     /*   ungetc(c,ficpar); */
                   10249:     /*   fgets(line, MAXLINE, ficpar); */
                   10250:     /*   fputs(line,stdout); */
                   10251:     /*   fputs(line,ficparo); */
                   10252:     /* } */
                   10253:     /* ungetc(c,ficpar); */
1.126     brouard  10254:     
                   10255:     estepm=0;
1.209     brouard  10256:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  10257:       
                   10258:       if (num_filled != 6) {
                   10259:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   10260:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   10261:        goto end;
                   10262:       }
                   10263:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   10264:     }
                   10265:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   10266:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   10267:     
1.209     brouard  10268:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  10269:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   10270:     if (fage <= 2) {
                   10271:       bage = ageminpar;
                   10272:       fage = agemaxpar;
                   10273:     }
                   10274:     
                   10275:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  10276:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   10277:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  10278:                
1.186     brouard  10279:     /* Other stuffs, more or less useful */    
1.126     brouard  10280:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10281:       ungetc(c,ficpar);
                   10282:       fgets(line, MAXLINE, ficpar);
1.141     brouard  10283:       fputs(line,stdout);
1.126     brouard  10284:       fputs(line,ficparo);
                   10285:     }
                   10286:     ungetc(c,ficpar);
                   10287:     
                   10288:     fscanf(ficpar,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav);
                   10289:     fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10290:     fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10291:     printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10292:     fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10293:     
                   10294:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10295:       ungetc(c,ficpar);
                   10296:       fgets(line, MAXLINE, ficpar);
1.141     brouard  10297:       fputs(line,stdout);
1.126     brouard  10298:       fputs(line,ficparo);
                   10299:     }
                   10300:     ungetc(c,ficpar);
                   10301:     
                   10302:     
                   10303:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   10304:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   10305:     
                   10306:     fscanf(ficpar,"pop_based=%d\n",&popbased);
1.193     brouard  10307:     fprintf(ficlog,"pop_based=%d\n",popbased);
1.126     brouard  10308:     fprintf(ficparo,"pop_based=%d\n",popbased);   
                   10309:     fprintf(ficres,"pop_based=%d\n",popbased);   
                   10310:     
                   10311:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10312:       ungetc(c,ficpar);
                   10313:       fgets(line, MAXLINE, ficpar);
1.141     brouard  10314:       fputs(line,stdout);
1.126     brouard  10315:       fputs(line,ficparo);
                   10316:     }
                   10317:     ungetc(c,ficpar);
                   10318:     
                   10319:     fscanf(ficpar,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj);
                   10320:     fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10321:     printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10322:     fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10323:     fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10324:     /* day and month of proj2 are not used but only year anproj2.*/
                   10325:     
1.217     brouard  10326:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10327:       ungetc(c,ficpar);
                   10328:       fgets(line, MAXLINE, ficpar);
                   10329:       fputs(line,stdout);
                   10330:       fputs(line,ficparo);
                   10331:     }
                   10332:     ungetc(c,ficpar);
                   10333:     
                   10334:     fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);
1.223     brouard  10335:     fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   10336:     fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   10337:     fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
1.217     brouard  10338:     /* day and month of proj2 are not used but only year anproj2.*/
1.126     brouard  10339:     
1.230     brouard  10340:     /* Results */
                   10341:     while(fgets(line, MAXLINE, ficpar)) {
                   10342:       /* If line starts with a # it is a comment */
                   10343:       if (line[0] == '#') {
                   10344:        numlinepar++;
                   10345:        fputs(line,stdout);
                   10346:        fputs(line,ficparo);
                   10347:        fputs(line,ficlog);
                   10348:        continue;
                   10349:       }else
                   10350:        break;
                   10351:     }
                   10352:     while((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   10353:       if (num_filled == 0)
                   10354:        resultline[0]='\0';
                   10355:       else if (num_filled != 1){
                   10356:        printf("ERROR %d: result line should be at minimum 'result=' %s\n",num_filled, line);
                   10357:       }
                   10358:       printf("Result %d: result line should be at minimum 'line=' %s, result=%s\n",num_filled, line, resultline);
                   10359:       decoderesult(resultline);
                   10360:       while(fgets(line, MAXLINE, ficpar)) {
                   10361:        /* If line starts with a # it is a comment */
                   10362:        if (line[0] == '#') {
                   10363:          numlinepar++;
                   10364:          fputs(line,stdout);
                   10365:          fputs(line,ficparo);
                   10366:          fputs(line,ficlog);
                   10367:          continue;
                   10368:        }else
                   10369:          break;
                   10370:       }
                   10371:       if (feof(ficpar))
                   10372:        break;
                   10373:       else{ /* Processess output results for this combination of covariate values */
                   10374:       }                                   
                   10375:     }
                   10376: 
                   10377: 
1.126     brouard  10378:     
1.230     brouard  10379:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  10380:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  10381:     
                   10382:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  10383:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  10384:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  10385: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10386: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  10387:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  10388: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10389: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10390:     }else{
1.218     brouard  10391:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p);
1.220     brouard  10392:     }
                   10393:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.225     brouard  10394:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,prevfcast,backcast, estepm, \
                   10395:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  10396:                
1.225     brouard  10397:     /*------------ free_vector  -------------*/
                   10398:     /*  chdir(path); */
1.220     brouard  10399:                
1.215     brouard  10400:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   10401:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   10402:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   10403:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  10404:     free_lvector(num,1,n);
                   10405:     free_vector(agedc,1,n);
                   10406:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   10407:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   10408:     fclose(ficparo);
                   10409:     fclose(ficres);
1.220     brouard  10410:                
                   10411:                
1.186     brouard  10412:     /* Other results (useful)*/
1.220     brouard  10413:                
                   10414:                
1.126     brouard  10415:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  10416:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   10417:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  10418:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  10419:     fclose(ficrespl);
                   10420: 
                   10421:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  10422:     /*#include "hpijx.h"*/
                   10423:     hPijx(p, bage, fage);
1.145     brouard  10424:     fclose(ficrespij);
1.227     brouard  10425:     
1.220     brouard  10426:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  10427:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  10428:     k=1;
1.126     brouard  10429:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  10430:     
1.219     brouard  10431:     /* Prevalence for each covariates in probs[age][status][cov] */
1.218     brouard  10432:     probs= ma3x(1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.126     brouard  10433:     for(i=1;i<=AGESUP;i++)
1.219     brouard  10434:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  10435:        for(k=1;k<=ncovcombmax;k++)
                   10436:          probs[i][j][k]=0.;
1.219     brouard  10437:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
                   10438:     if (mobilav!=0 ||mobilavproj !=0 ) {
                   10439:       mobaverages= ma3x(1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.227     brouard  10440:       for(i=1;i<=AGESUP;i++)
                   10441:        for(j=1;j<=nlstate;j++)
                   10442:          for(k=1;k<=ncovcombmax;k++)
                   10443:            mobaverages[i][j][k]=0.;
1.219     brouard  10444:       mobaverage=mobaverages;
                   10445:       if (mobilav!=0) {
1.227     brouard  10446:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   10447:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   10448:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   10449:        }
1.219     brouard  10450:       }
                   10451:       /* /\* Prevalence for each covariates in probs[age][status][cov] *\/ */
                   10452:       /* prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   10453:       else if (mobilavproj !=0) {
1.227     brouard  10454:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   10455:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   10456:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   10457:        }
1.219     brouard  10458:       }
                   10459:     }/* end if moving average */
1.227     brouard  10460:     
1.126     brouard  10461:     /*---------- Forecasting ------------------*/
                   10462:     /*if((stepm == 1) && (strcmp(model,".")==0)){*/
                   10463:     if(prevfcast==1){
                   10464:       /*    if(stepm ==1){*/
1.225     brouard  10465:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  10466:     }
1.217     brouard  10467:     if(backcast==1){
1.219     brouard  10468:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   10469:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   10470:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   10471: 
                   10472:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   10473: 
                   10474:       bprlim=matrix(1,nlstate,1,nlstate);
                   10475:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   10476:       fclose(ficresplb);
                   10477: 
1.222     brouard  10478:       hBijx(p, bage, fage, mobaverage);
                   10479:       fclose(ficrespijb);
1.219     brouard  10480:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   10481: 
                   10482:       /* prevbackforecast(fileresu, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, mobilavproj,
1.225     brouard  10483:         bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
1.219     brouard  10484:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   10485:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   10486:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   10487:     }
1.217     brouard  10488:     
1.186     brouard  10489:  
                   10490:     /* ------ Other prevalence ratios------------ */
1.126     brouard  10491: 
1.215     brouard  10492:     free_ivector(wav,1,imx);
                   10493:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   10494:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   10495:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  10496:                
                   10497:                
1.127     brouard  10498:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  10499:                
1.201     brouard  10500:     strcpy(filerese,"E_");
                   10501:     strcat(filerese,fileresu);
1.126     brouard  10502:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   10503:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   10504:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   10505:     }
1.208     brouard  10506:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   10507:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.219     brouard  10508:                
1.227     brouard  10509:     for (k=1; k <= (int) pow(2,cptcoveff); k++){ /* For any combination of dummy covariates, fixed and varying */
1.219     brouard  10510:       fprintf(ficreseij,"\n#****** ");
1.225     brouard  10511:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  10512:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.219     brouard  10513:       }
                   10514:       fprintf(ficreseij,"******\n");
                   10515:       
                   10516:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   10517:       oldm=oldms;savm=savms;
                   10518:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart);  
1.127     brouard  10519:       
1.219     brouard  10520:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  10521:     }
                   10522:     fclose(ficreseij);
1.208     brouard  10523:     printf("done evsij\n");fflush(stdout);
                   10524:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.218     brouard  10525:                
1.227     brouard  10526:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  10527:                
                   10528:                
1.201     brouard  10529:     strcpy(filerest,"T_");
                   10530:     strcat(filerest,fileresu);
1.127     brouard  10531:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   10532:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   10533:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   10534:     }
1.208     brouard  10535:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   10536:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.218     brouard  10537:                
1.126     brouard  10538: 
1.201     brouard  10539:     strcpy(fileresstde,"STDE_");
                   10540:     strcat(fileresstde,fileresu);
1.126     brouard  10541:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  10542:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   10543:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  10544:     }
1.227     brouard  10545:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   10546:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  10547: 
1.201     brouard  10548:     strcpy(filerescve,"CVE_");
                   10549:     strcat(filerescve,fileresu);
1.126     brouard  10550:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  10551:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   10552:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  10553:     }
1.227     brouard  10554:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   10555:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  10556: 
1.201     brouard  10557:     strcpy(fileresv,"V_");
                   10558:     strcat(fileresv,fileresu);
1.126     brouard  10559:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   10560:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   10561:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   10562:     }
1.227     brouard  10563:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   10564:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  10565: 
1.145     brouard  10566:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   10567:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   10568:           
1.225     brouard  10569:     for (k=1; k <= (int) pow(2,cptcoveff); k++){
1.227     brouard  10570:       printf("\n#****** ");
1.208     brouard  10571:       fprintf(ficrest,"\n#****** ");
1.227     brouard  10572:       fprintf(ficlog,"\n#****** ");
                   10573:       for(j=1;j<=cptcoveff;j++){ 
                   10574:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10575:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10576:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10577:       }
1.208     brouard  10578:       fprintf(ficrest,"******\n");
1.227     brouard  10579:       fprintf(ficlog,"******\n");
                   10580:       printf("******\n");
1.208     brouard  10581:       
                   10582:       fprintf(ficresstdeij,"\n#****** ");
                   10583:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  10584:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  10585:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10586:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  10587:       }
                   10588:       fprintf(ficresstdeij,"******\n");
                   10589:       fprintf(ficrescveij,"******\n");
                   10590:       
                   10591:       fprintf(ficresvij,"\n#****** ");
1.225     brouard  10592:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  10593:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  10594:       fprintf(ficresvij,"******\n");
                   10595:       
                   10596:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   10597:       oldm=oldms;savm=savms;
1.227     brouard  10598:       printf(" cvevsij combination#=%d, ",k);
                   10599:       fprintf(ficlog, " cvevsij combination#=%d, ",k);
1.208     brouard  10600:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart);
                   10601:       printf(" end cvevsij \n ");
                   10602:       fprintf(ficlog, " end cvevsij \n ");
                   10603:       
                   10604:       /*
                   10605:        */
                   10606:       /* goto endfree; */
                   10607:       
                   10608:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   10609:       pstamp(ficrest);
                   10610:       
                   10611:       
                   10612:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  10613:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   10614:        cptcod= 0; /* To be deleted */
                   10615:        printf("varevsij vpopbased=%d \n",vpopbased);
                   10616:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
                   10617:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart); /* cptcod not initialized Intel */
                   10618:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   10619:        if(vpopbased==1)
                   10620:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   10621:        else
                   10622:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   10623:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   10624:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   10625:        fprintf(ficrest,"\n");
                   10626:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   10627:        epj=vector(1,nlstate+1);
                   10628:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   10629:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   10630:        for(age=bage; age <=fage ;age++){
                   10631:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k); /*ZZ Is it the correct prevalim */
                   10632:          if (vpopbased==1) {
                   10633:            if(mobilav ==0){
                   10634:              for(i=1; i<=nlstate;i++)
                   10635:                prlim[i][i]=probs[(int)age][i][k];
                   10636:            }else{ /* mobilav */ 
                   10637:              for(i=1; i<=nlstate;i++)
                   10638:                prlim[i][i]=mobaverage[(int)age][i][k];
                   10639:            }
                   10640:          }
1.219     brouard  10641:          
1.227     brouard  10642:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   10643:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   10644:          /* printf(" age %4.0f ",age); */
                   10645:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   10646:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   10647:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   10648:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   10649:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   10650:            }
                   10651:            epj[nlstate+1] +=epj[j];
                   10652:          }
                   10653:          /* printf(" age %4.0f \n",age); */
1.219     brouard  10654:          
1.227     brouard  10655:          for(i=1, vepp=0.;i <=nlstate;i++)
                   10656:            for(j=1;j <=nlstate;j++)
                   10657:              vepp += vareij[i][j][(int)age];
                   10658:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   10659:          for(j=1;j <=nlstate;j++){
                   10660:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   10661:          }
                   10662:          fprintf(ficrest,"\n");
                   10663:        }
1.208     brouard  10664:       } /* End vpopbased */
                   10665:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   10666:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   10667:       free_vector(epj,1,nlstate+1);
                   10668:       printf("done \n");fflush(stdout);
                   10669:       fprintf(ficlog,"done\n");fflush(ficlog);
                   10670:       
1.145     brouard  10671:       /*}*/
1.208     brouard  10672:     } /* End k */
1.227     brouard  10673: 
                   10674:     printf("done State-specific expectancies\n");fflush(stdout);
                   10675:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   10676: 
1.126     brouard  10677:     /*------- Variance of period (stable) prevalence------*/   
1.227     brouard  10678:     
1.201     brouard  10679:     strcpy(fileresvpl,"VPL_");
                   10680:     strcat(fileresvpl,fileresu);
1.126     brouard  10681:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   10682:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   10683:       exit(0);
                   10684:     }
1.208     brouard  10685:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   10686:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.227     brouard  10687:     
1.145     brouard  10688:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   10689:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
1.227     brouard  10690:     
1.225     brouard  10691:     for (k=1; k <= (int) pow(2,cptcoveff); k++){
1.227     brouard  10692:       fprintf(ficresvpl,"\n#****** ");
                   10693:       printf("\n#****** ");
                   10694:       fprintf(ficlog,"\n#****** ");
                   10695:       for(j=1;j<=cptcoveff;j++) {
                   10696:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10697:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10698:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10699:       }
                   10700:       fprintf(ficresvpl,"******\n");
                   10701:       printf("******\n");
                   10702:       fprintf(ficlog,"******\n");
                   10703:       
                   10704:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   10705:       oldm=oldms;savm=savms;
                   10706:       varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, strstart);
                   10707:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
1.145     brouard  10708:       /*}*/
1.126     brouard  10709:     }
1.227     brouard  10710:     
1.126     brouard  10711:     fclose(ficresvpl);
1.208     brouard  10712:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   10713:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
1.227     brouard  10714:     
                   10715:     free_vector(weight,1,n);
                   10716:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   10717:     free_imatrix(s,1,maxwav+1,1,n);
                   10718:     free_matrix(anint,1,maxwav,1,n); 
                   10719:     free_matrix(mint,1,maxwav,1,n);
                   10720:     free_ivector(cod,1,n);
                   10721:     free_ivector(tab,1,NCOVMAX);
                   10722:     fclose(ficresstdeij);
                   10723:     fclose(ficrescveij);
                   10724:     fclose(ficresvij);
                   10725:     fclose(ficrest);
                   10726:     fclose(ficpar);
                   10727:     
                   10728:     
1.126     brouard  10729:     /*---------- End : free ----------------*/
1.219     brouard  10730:     if (mobilav!=0 ||mobilavproj !=0)
                   10731:       free_ma3x(mobaverages,1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
1.218     brouard  10732:     free_ma3x(probs,1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  10733:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   10734:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  10735:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  10736:   /* endfree:*/
                   10737:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   10738:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   10739:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   10740:   free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
                   10741:   free_ma3x(cotvar,1,maxwav,1,ntv,1,n);
                   10742:   free_matrix(coqvar,1,maxwav,1,n);
                   10743:   free_matrix(covar,0,NCOVMAX,1,n);
                   10744:   free_matrix(matcov,1,npar,1,npar);
                   10745:   free_matrix(hess,1,npar,1,npar);
                   10746:   /*free_vector(delti,1,npar);*/
                   10747:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   10748:   free_matrix(agev,1,maxwav,1,imx);
                   10749:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   10750:   
                   10751:   free_ivector(ncodemax,1,NCOVMAX);
                   10752:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   10753:   free_ivector(Dummy,-1,NCOVMAX);
                   10754:   free_ivector(Fixed,-1,NCOVMAX);
                   10755:   free_ivector(Typevar,-1,NCOVMAX);
                   10756:   free_ivector(Tvar,1,NCOVMAX);
1.231   ! brouard  10757:   free_ivector(TvarFD,1,NCOVMAX);
        !          10758:   free_ivector(TvarFDind,1,NCOVMAX);
        !          10759:   free_ivector(TvarFQ,1,NCOVMAX);
        !          10760:   free_ivector(TvarFQind,1,NCOVMAX);
        !          10761:   free_ivector(TvarVD,1,NCOVMAX);
        !          10762:   free_ivector(TvarVDind,1,NCOVMAX);
        !          10763:   free_ivector(TvarVQ,1,NCOVMAX);
        !          10764:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  10765:   free_ivector(Tvarsel,1,NCOVMAX);
                   10766:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  10767:   free_ivector(Tposprod,1,NCOVMAX);
                   10768:   free_ivector(Tprod,1,NCOVMAX);
                   10769:   free_ivector(Tvaraff,1,NCOVMAX);
                   10770:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   10771:   free_ivector(Tage,1,NCOVMAX);
                   10772:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  10773:   free_ivector(TmodelInvind,1,NCOVMAX);
                   10774:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  10775:   
                   10776:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   10777:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  10778:   fflush(fichtm);
                   10779:   fflush(ficgp);
                   10780:   
1.227     brouard  10781:   
1.126     brouard  10782:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  10783:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   10784:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  10785:   }else{
                   10786:     printf("End of Imach\n");
                   10787:     fprintf(ficlog,"End of Imach\n");
                   10788:   }
                   10789:   printf("See log file on %s\n",filelog);
                   10790:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  10791:   /*(void) gettimeofday(&end_time,&tzp);*/
                   10792:   rend_time = time(NULL);  
                   10793:   end_time = *localtime(&rend_time);
                   10794:   /* tml = *localtime(&end_time.tm_sec); */
                   10795:   strcpy(strtend,asctime(&end_time));
1.126     brouard  10796:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   10797:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  10798:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  10799:   
1.157     brouard  10800:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   10801:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   10802:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  10803:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   10804: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   10805:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   10806:   fclose(fichtm);
                   10807:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   10808:   fclose(fichtmcov);
                   10809:   fclose(ficgp);
                   10810:   fclose(ficlog);
                   10811:   /*------ End -----------*/
1.227     brouard  10812:   
                   10813:   
                   10814:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  10815: #ifdef WIN32
1.227     brouard  10816:   if (_chdir(pathcd) != 0)
                   10817:     printf("Can't move to directory %s!\n",path);
                   10818:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  10819: #else
1.227     brouard  10820:     if(chdir(pathcd) != 0)
                   10821:       printf("Can't move to directory %s!\n", path);
                   10822:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  10823: #endif 
1.126     brouard  10824:     printf("Current directory %s!\n",pathcd);
                   10825:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   10826:   sprintf(plotcmd,"gnuplot");
1.157     brouard  10827: #ifdef _WIN32
1.126     brouard  10828:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   10829: #endif
                   10830:   if(!stat(plotcmd,&info)){
1.158     brouard  10831:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  10832:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  10833:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  10834:     }else
                   10835:       strcpy(pplotcmd,plotcmd);
1.157     brouard  10836: #ifdef __unix
1.126     brouard  10837:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   10838:     if(!stat(plotcmd,&info)){
1.158     brouard  10839:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  10840:     }else
                   10841:       strcpy(pplotcmd,plotcmd);
                   10842: #endif
                   10843:   }else
                   10844:     strcpy(pplotcmd,plotcmd);
                   10845:   
                   10846:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  10847:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  10848:   
1.126     brouard  10849:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  10850:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  10851:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  10852:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  10853:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  10854:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  10855:   }
1.158     brouard  10856:   printf(" Successful, please wait...");
1.126     brouard  10857:   while (z[0] != 'q') {
                   10858:     /* chdir(path); */
1.154     brouard  10859:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  10860:     scanf("%s",z);
                   10861: /*     if (z[0] == 'c') system("./imach"); */
                   10862:     if (z[0] == 'e') {
1.158     brouard  10863: #ifdef __APPLE__
1.152     brouard  10864:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  10865: #elif __linux
                   10866:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  10867: #else
1.152     brouard  10868:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  10869: #endif
                   10870:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   10871:       system(pplotcmd);
1.126     brouard  10872:     }
                   10873:     else if (z[0] == 'g') system(plotcmd);
                   10874:     else if (z[0] == 'q') exit(0);
                   10875:   }
1.227     brouard  10876: end:
1.126     brouard  10877:   while (z[0] != 'q') {
1.195     brouard  10878:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  10879:     scanf("%s",z);
                   10880:   }
                   10881: }

FreeBSD-CVSweb <freebsd-cvsweb@FreeBSD.org>