Annotation of imach/src/imach.c, revision 1.234

1.234   ! brouard     1: /* $Id: imach.c,v 1.233 2016/08/23 07:40:50 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.234   ! brouard     4:   Revision 1.233  2016/08/23 07:40:50  brouard
        !             5:   Summary: not working
        !             6: 
1.233     brouard     7:   Revision 1.232  2016/08/22 14:20:21  brouard
                      8:   Summary: not working
                      9: 
1.232     brouard    10:   Revision 1.231  2016/08/22 07:17:15  brouard
                     11:   Summary: not working
                     12: 
1.231     brouard    13:   Revision 1.230  2016/08/22 06:55:53  brouard
                     14:   Summary: Not working
                     15: 
1.230     brouard    16:   Revision 1.229  2016/07/23 09:45:53  brouard
                     17:   Summary: Completing for func too
                     18: 
1.229     brouard    19:   Revision 1.228  2016/07/22 17:45:30  brouard
                     20:   Summary: Fixing some arrays, still debugging
                     21: 
1.227     brouard    22:   Revision 1.226  2016/07/12 18:42:34  brouard
                     23:   Summary: temp
                     24: 
1.226     brouard    25:   Revision 1.225  2016/07/12 08:40:03  brouard
                     26:   Summary: saving but not running
                     27: 
1.225     brouard    28:   Revision 1.224  2016/07/01 13:16:01  brouard
                     29:   Summary: Fixes
                     30: 
1.224     brouard    31:   Revision 1.223  2016/02/19 09:23:35  brouard
                     32:   Summary: temporary
                     33: 
1.223     brouard    34:   Revision 1.222  2016/02/17 08:14:50  brouard
                     35:   Summary: Probably last 0.98 stable version 0.98r6
                     36: 
1.222     brouard    37:   Revision 1.221  2016/02/15 23:35:36  brouard
                     38:   Summary: minor bug
                     39: 
1.220     brouard    40:   Revision 1.219  2016/02/15 00:48:12  brouard
                     41:   *** empty log message ***
                     42: 
1.219     brouard    43:   Revision 1.218  2016/02/12 11:29:23  brouard
                     44:   Summary: 0.99 Back projections
                     45: 
1.218     brouard    46:   Revision 1.217  2015/12/23 17:18:31  brouard
                     47:   Summary: Experimental backcast
                     48: 
1.217     brouard    49:   Revision 1.216  2015/12/18 17:32:11  brouard
                     50:   Summary: 0.98r4 Warning and status=-2
                     51: 
                     52:   Version 0.98r4 is now:
                     53:    - displaying an error when status is -1, date of interview unknown and date of death known;
                     54:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                     55:   Older changes concerning s=-2, dating from 2005 have been supersed.
                     56: 
1.216     brouard    57:   Revision 1.215  2015/12/16 08:52:24  brouard
                     58:   Summary: 0.98r4 working
                     59: 
1.215     brouard    60:   Revision 1.214  2015/12/16 06:57:54  brouard
                     61:   Summary: temporary not working
                     62: 
1.214     brouard    63:   Revision 1.213  2015/12/11 18:22:17  brouard
                     64:   Summary: 0.98r4
                     65: 
1.213     brouard    66:   Revision 1.212  2015/11/21 12:47:24  brouard
                     67:   Summary: minor typo
                     68: 
1.212     brouard    69:   Revision 1.211  2015/11/21 12:41:11  brouard
                     70:   Summary: 0.98r3 with some graph of projected cross-sectional
                     71: 
                     72:   Author: Nicolas Brouard
                     73: 
1.211     brouard    74:   Revision 1.210  2015/11/18 17:41:20  brouard
                     75:   Summary: Start working on projected prevalences
                     76: 
1.210     brouard    77:   Revision 1.209  2015/11/17 22:12:03  brouard
                     78:   Summary: Adding ftolpl parameter
                     79:   Author: N Brouard
                     80: 
                     81:   We had difficulties to get smoothed confidence intervals. It was due
                     82:   to the period prevalence which wasn't computed accurately. The inner
                     83:   parameter ftolpl is now an outer parameter of the .imach parameter
                     84:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                     85:   computation are long.
                     86: 
1.209     brouard    87:   Revision 1.208  2015/11/17 14:31:57  brouard
                     88:   Summary: temporary
                     89: 
1.208     brouard    90:   Revision 1.207  2015/10/27 17:36:57  brouard
                     91:   *** empty log message ***
                     92: 
1.207     brouard    93:   Revision 1.206  2015/10/24 07:14:11  brouard
                     94:   *** empty log message ***
                     95: 
1.206     brouard    96:   Revision 1.205  2015/10/23 15:50:53  brouard
                     97:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                     98: 
1.205     brouard    99:   Revision 1.204  2015/10/01 16:20:26  brouard
                    100:   Summary: Some new graphs of contribution to likelihood
                    101: 
1.204     brouard   102:   Revision 1.203  2015/09/30 17:45:14  brouard
                    103:   Summary: looking at better estimation of the hessian
                    104: 
                    105:   Also a better criteria for convergence to the period prevalence And
                    106:   therefore adding the number of years needed to converge. (The
                    107:   prevalence in any alive state shold sum to one
                    108: 
1.203     brouard   109:   Revision 1.202  2015/09/22 19:45:16  brouard
                    110:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    111: 
1.202     brouard   112:   Revision 1.201  2015/09/15 17:34:58  brouard
                    113:   Summary: 0.98r0
                    114: 
                    115:   - Some new graphs like suvival functions
                    116:   - Some bugs fixed like model=1+age+V2.
                    117: 
1.201     brouard   118:   Revision 1.200  2015/09/09 16:53:55  brouard
                    119:   Summary: Big bug thanks to Flavia
                    120: 
                    121:   Even model=1+age+V2. did not work anymore
                    122: 
1.200     brouard   123:   Revision 1.199  2015/09/07 14:09:23  brouard
                    124:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    125: 
1.199     brouard   126:   Revision 1.198  2015/09/03 07:14:39  brouard
                    127:   Summary: 0.98q5 Flavia
                    128: 
1.198     brouard   129:   Revision 1.197  2015/09/01 18:24:39  brouard
                    130:   *** empty log message ***
                    131: 
1.197     brouard   132:   Revision 1.196  2015/08/18 23:17:52  brouard
                    133:   Summary: 0.98q5
                    134: 
1.196     brouard   135:   Revision 1.195  2015/08/18 16:28:39  brouard
                    136:   Summary: Adding a hack for testing purpose
                    137: 
                    138:   After reading the title, ftol and model lines, if the comment line has
                    139:   a q, starting with #q, the answer at the end of the run is quit. It
                    140:   permits to run test files in batch with ctest. The former workaround was
                    141:   $ echo q | imach foo.imach
                    142: 
1.195     brouard   143:   Revision 1.194  2015/08/18 13:32:00  brouard
                    144:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    145: 
1.194     brouard   146:   Revision 1.193  2015/08/04 07:17:42  brouard
                    147:   Summary: 0.98q4
                    148: 
1.193     brouard   149:   Revision 1.192  2015/07/16 16:49:02  brouard
                    150:   Summary: Fixing some outputs
                    151: 
1.192     brouard   152:   Revision 1.191  2015/07/14 10:00:33  brouard
                    153:   Summary: Some fixes
                    154: 
1.191     brouard   155:   Revision 1.190  2015/05/05 08:51:13  brouard
                    156:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    157: 
                    158:   Fix 1+age+.
                    159: 
1.190     brouard   160:   Revision 1.189  2015/04/30 14:45:16  brouard
                    161:   Summary: 0.98q2
                    162: 
1.189     brouard   163:   Revision 1.188  2015/04/30 08:27:53  brouard
                    164:   *** empty log message ***
                    165: 
1.188     brouard   166:   Revision 1.187  2015/04/29 09:11:15  brouard
                    167:   *** empty log message ***
                    168: 
1.187     brouard   169:   Revision 1.186  2015/04/23 12:01:52  brouard
                    170:   Summary: V1*age is working now, version 0.98q1
                    171: 
                    172:   Some codes had been disabled in order to simplify and Vn*age was
                    173:   working in the optimization phase, ie, giving correct MLE parameters,
                    174:   but, as usual, outputs were not correct and program core dumped.
                    175: 
1.186     brouard   176:   Revision 1.185  2015/03/11 13:26:42  brouard
                    177:   Summary: Inclusion of compile and links command line for Intel Compiler
                    178: 
1.185     brouard   179:   Revision 1.184  2015/03/11 11:52:39  brouard
                    180:   Summary: Back from Windows 8. Intel Compiler
                    181: 
1.184     brouard   182:   Revision 1.183  2015/03/10 20:34:32  brouard
                    183:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    184: 
                    185:   We use directest instead of original Powell test; probably no
                    186:   incidence on the results, but better justifications;
                    187:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    188:   wrong results.
                    189: 
1.183     brouard   190:   Revision 1.182  2015/02/12 08:19:57  brouard
                    191:   Summary: Trying to keep directest which seems simpler and more general
                    192:   Author: Nicolas Brouard
                    193: 
1.182     brouard   194:   Revision 1.181  2015/02/11 23:22:24  brouard
                    195:   Summary: Comments on Powell added
                    196: 
                    197:   Author:
                    198: 
1.181     brouard   199:   Revision 1.180  2015/02/11 17:33:45  brouard
                    200:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    201: 
1.180     brouard   202:   Revision 1.179  2015/01/04 09:57:06  brouard
                    203:   Summary: back to OS/X
                    204: 
1.179     brouard   205:   Revision 1.178  2015/01/04 09:35:48  brouard
                    206:   *** empty log message ***
                    207: 
1.178     brouard   208:   Revision 1.177  2015/01/03 18:40:56  brouard
                    209:   Summary: Still testing ilc32 on OSX
                    210: 
1.177     brouard   211:   Revision 1.176  2015/01/03 16:45:04  brouard
                    212:   *** empty log message ***
                    213: 
1.176     brouard   214:   Revision 1.175  2015/01/03 16:33:42  brouard
                    215:   *** empty log message ***
                    216: 
1.175     brouard   217:   Revision 1.174  2015/01/03 16:15:49  brouard
                    218:   Summary: Still in cross-compilation
                    219: 
1.174     brouard   220:   Revision 1.173  2015/01/03 12:06:26  brouard
                    221:   Summary: trying to detect cross-compilation
                    222: 
1.173     brouard   223:   Revision 1.172  2014/12/27 12:07:47  brouard
                    224:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    225: 
1.172     brouard   226:   Revision 1.171  2014/12/23 13:26:59  brouard
                    227:   Summary: Back from Visual C
                    228: 
                    229:   Still problem with utsname.h on Windows
                    230: 
1.171     brouard   231:   Revision 1.170  2014/12/23 11:17:12  brouard
                    232:   Summary: Cleaning some \%% back to %%
                    233: 
                    234:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    235: 
1.170     brouard   236:   Revision 1.169  2014/12/22 23:08:31  brouard
                    237:   Summary: 0.98p
                    238: 
                    239:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    240: 
1.169     brouard   241:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   242:   Summary: update
1.169     brouard   243: 
1.168     brouard   244:   Revision 1.167  2014/12/22 13:50:56  brouard
                    245:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    246: 
                    247:   Testing on Linux 64
                    248: 
1.167     brouard   249:   Revision 1.166  2014/12/22 11:40:47  brouard
                    250:   *** empty log message ***
                    251: 
1.166     brouard   252:   Revision 1.165  2014/12/16 11:20:36  brouard
                    253:   Summary: After compiling on Visual C
                    254: 
                    255:   * imach.c (Module): Merging 1.61 to 1.162
                    256: 
1.165     brouard   257:   Revision 1.164  2014/12/16 10:52:11  brouard
                    258:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    259: 
                    260:   * imach.c (Module): Merging 1.61 to 1.162
                    261: 
1.164     brouard   262:   Revision 1.163  2014/12/16 10:30:11  brouard
                    263:   * imach.c (Module): Merging 1.61 to 1.162
                    264: 
1.163     brouard   265:   Revision 1.162  2014/09/25 11:43:39  brouard
                    266:   Summary: temporary backup 0.99!
                    267: 
1.162     brouard   268:   Revision 1.1  2014/09/16 11:06:58  brouard
                    269:   Summary: With some code (wrong) for nlopt
                    270: 
                    271:   Author:
                    272: 
                    273:   Revision 1.161  2014/09/15 20:41:41  brouard
                    274:   Summary: Problem with macro SQR on Intel compiler
                    275: 
1.161     brouard   276:   Revision 1.160  2014/09/02 09:24:05  brouard
                    277:   *** empty log message ***
                    278: 
1.160     brouard   279:   Revision 1.159  2014/09/01 10:34:10  brouard
                    280:   Summary: WIN32
                    281:   Author: Brouard
                    282: 
1.159     brouard   283:   Revision 1.158  2014/08/27 17:11:51  brouard
                    284:   *** empty log message ***
                    285: 
1.158     brouard   286:   Revision 1.157  2014/08/27 16:26:55  brouard
                    287:   Summary: Preparing windows Visual studio version
                    288:   Author: Brouard
                    289: 
                    290:   In order to compile on Visual studio, time.h is now correct and time_t
                    291:   and tm struct should be used. difftime should be used but sometimes I
                    292:   just make the differences in raw time format (time(&now).
                    293:   Trying to suppress #ifdef LINUX
                    294:   Add xdg-open for __linux in order to open default browser.
                    295: 
1.157     brouard   296:   Revision 1.156  2014/08/25 20:10:10  brouard
                    297:   *** empty log message ***
                    298: 
1.156     brouard   299:   Revision 1.155  2014/08/25 18:32:34  brouard
                    300:   Summary: New compile, minor changes
                    301:   Author: Brouard
                    302: 
1.155     brouard   303:   Revision 1.154  2014/06/20 17:32:08  brouard
                    304:   Summary: Outputs now all graphs of convergence to period prevalence
                    305: 
1.154     brouard   306:   Revision 1.153  2014/06/20 16:45:46  brouard
                    307:   Summary: If 3 live state, convergence to period prevalence on same graph
                    308:   Author: Brouard
                    309: 
1.153     brouard   310:   Revision 1.152  2014/06/18 17:54:09  brouard
                    311:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    312: 
1.152     brouard   313:   Revision 1.151  2014/06/18 16:43:30  brouard
                    314:   *** empty log message ***
                    315: 
1.151     brouard   316:   Revision 1.150  2014/06/18 16:42:35  brouard
                    317:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    318:   Author: brouard
                    319: 
1.150     brouard   320:   Revision 1.149  2014/06/18 15:51:14  brouard
                    321:   Summary: Some fixes in parameter files errors
                    322:   Author: Nicolas Brouard
                    323: 
1.149     brouard   324:   Revision 1.148  2014/06/17 17:38:48  brouard
                    325:   Summary: Nothing new
                    326:   Author: Brouard
                    327: 
                    328:   Just a new packaging for OS/X version 0.98nS
                    329: 
1.148     brouard   330:   Revision 1.147  2014/06/16 10:33:11  brouard
                    331:   *** empty log message ***
                    332: 
1.147     brouard   333:   Revision 1.146  2014/06/16 10:20:28  brouard
                    334:   Summary: Merge
                    335:   Author: Brouard
                    336: 
                    337:   Merge, before building revised version.
                    338: 
1.146     brouard   339:   Revision 1.145  2014/06/10 21:23:15  brouard
                    340:   Summary: Debugging with valgrind
                    341:   Author: Nicolas Brouard
                    342: 
                    343:   Lot of changes in order to output the results with some covariates
                    344:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    345:   improve the code.
                    346:   No more memory valgrind error but a lot has to be done in order to
                    347:   continue the work of splitting the code into subroutines.
                    348:   Also, decodemodel has been improved. Tricode is still not
                    349:   optimal. nbcode should be improved. Documentation has been added in
                    350:   the source code.
                    351: 
1.144     brouard   352:   Revision 1.143  2014/01/26 09:45:38  brouard
                    353:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    354: 
                    355:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    356:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    357: 
1.143     brouard   358:   Revision 1.142  2014/01/26 03:57:36  brouard
                    359:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    360: 
                    361:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    362: 
1.142     brouard   363:   Revision 1.141  2014/01/26 02:42:01  brouard
                    364:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    365: 
1.141     brouard   366:   Revision 1.140  2011/09/02 10:37:54  brouard
                    367:   Summary: times.h is ok with mingw32 now.
                    368: 
1.140     brouard   369:   Revision 1.139  2010/06/14 07:50:17  brouard
                    370:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    371:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    372: 
1.139     brouard   373:   Revision 1.138  2010/04/30 18:19:40  brouard
                    374:   *** empty log message ***
                    375: 
1.138     brouard   376:   Revision 1.137  2010/04/29 18:11:38  brouard
                    377:   (Module): Checking covariates for more complex models
                    378:   than V1+V2. A lot of change to be done. Unstable.
                    379: 
1.137     brouard   380:   Revision 1.136  2010/04/26 20:30:53  brouard
                    381:   (Module): merging some libgsl code. Fixing computation
                    382:   of likelione (using inter/intrapolation if mle = 0) in order to
                    383:   get same likelihood as if mle=1.
                    384:   Some cleaning of code and comments added.
                    385: 
1.136     brouard   386:   Revision 1.135  2009/10/29 15:33:14  brouard
                    387:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    388: 
1.135     brouard   389:   Revision 1.134  2009/10/29 13:18:53  brouard
                    390:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    391: 
1.134     brouard   392:   Revision 1.133  2009/07/06 10:21:25  brouard
                    393:   just nforces
                    394: 
1.133     brouard   395:   Revision 1.132  2009/07/06 08:22:05  brouard
                    396:   Many tings
                    397: 
1.132     brouard   398:   Revision 1.131  2009/06/20 16:22:47  brouard
                    399:   Some dimensions resccaled
                    400: 
1.131     brouard   401:   Revision 1.130  2009/05/26 06:44:34  brouard
                    402:   (Module): Max Covariate is now set to 20 instead of 8. A
                    403:   lot of cleaning with variables initialized to 0. Trying to make
                    404:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    405: 
1.130     brouard   406:   Revision 1.129  2007/08/31 13:49:27  lievre
                    407:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    408: 
1.129     lievre    409:   Revision 1.128  2006/06/30 13:02:05  brouard
                    410:   (Module): Clarifications on computing e.j
                    411: 
1.128     brouard   412:   Revision 1.127  2006/04/28 18:11:50  brouard
                    413:   (Module): Yes the sum of survivors was wrong since
                    414:   imach-114 because nhstepm was no more computed in the age
                    415:   loop. Now we define nhstepma in the age loop.
                    416:   (Module): In order to speed up (in case of numerous covariates) we
                    417:   compute health expectancies (without variances) in a first step
                    418:   and then all the health expectancies with variances or standard
                    419:   deviation (needs data from the Hessian matrices) which slows the
                    420:   computation.
                    421:   In the future we should be able to stop the program is only health
                    422:   expectancies and graph are needed without standard deviations.
                    423: 
1.127     brouard   424:   Revision 1.126  2006/04/28 17:23:28  brouard
                    425:   (Module): Yes the sum of survivors was wrong since
                    426:   imach-114 because nhstepm was no more computed in the age
                    427:   loop. Now we define nhstepma in the age loop.
                    428:   Version 0.98h
                    429: 
1.126     brouard   430:   Revision 1.125  2006/04/04 15:20:31  lievre
                    431:   Errors in calculation of health expectancies. Age was not initialized.
                    432:   Forecasting file added.
                    433: 
                    434:   Revision 1.124  2006/03/22 17:13:53  lievre
                    435:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    436:   The log-likelihood is printed in the log file
                    437: 
                    438:   Revision 1.123  2006/03/20 10:52:43  brouard
                    439:   * imach.c (Module): <title> changed, corresponds to .htm file
                    440:   name. <head> headers where missing.
                    441: 
                    442:   * imach.c (Module): Weights can have a decimal point as for
                    443:   English (a comma might work with a correct LC_NUMERIC environment,
                    444:   otherwise the weight is truncated).
                    445:   Modification of warning when the covariates values are not 0 or
                    446:   1.
                    447:   Version 0.98g
                    448: 
                    449:   Revision 1.122  2006/03/20 09:45:41  brouard
                    450:   (Module): Weights can have a decimal point as for
                    451:   English (a comma might work with a correct LC_NUMERIC environment,
                    452:   otherwise the weight is truncated).
                    453:   Modification of warning when the covariates values are not 0 or
                    454:   1.
                    455:   Version 0.98g
                    456: 
                    457:   Revision 1.121  2006/03/16 17:45:01  lievre
                    458:   * imach.c (Module): Comments concerning covariates added
                    459: 
                    460:   * imach.c (Module): refinements in the computation of lli if
                    461:   status=-2 in order to have more reliable computation if stepm is
                    462:   not 1 month. Version 0.98f
                    463: 
                    464:   Revision 1.120  2006/03/16 15:10:38  lievre
                    465:   (Module): refinements in the computation of lli if
                    466:   status=-2 in order to have more reliable computation if stepm is
                    467:   not 1 month. Version 0.98f
                    468: 
                    469:   Revision 1.119  2006/03/15 17:42:26  brouard
                    470:   (Module): Bug if status = -2, the loglikelihood was
                    471:   computed as likelihood omitting the logarithm. Version O.98e
                    472: 
                    473:   Revision 1.118  2006/03/14 18:20:07  brouard
                    474:   (Module): varevsij Comments added explaining the second
                    475:   table of variances if popbased=1 .
                    476:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    477:   (Module): Function pstamp added
                    478:   (Module): Version 0.98d
                    479: 
                    480:   Revision 1.117  2006/03/14 17:16:22  brouard
                    481:   (Module): varevsij Comments added explaining the second
                    482:   table of variances if popbased=1 .
                    483:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    484:   (Module): Function pstamp added
                    485:   (Module): Version 0.98d
                    486: 
                    487:   Revision 1.116  2006/03/06 10:29:27  brouard
                    488:   (Module): Variance-covariance wrong links and
                    489:   varian-covariance of ej. is needed (Saito).
                    490: 
                    491:   Revision 1.115  2006/02/27 12:17:45  brouard
                    492:   (Module): One freematrix added in mlikeli! 0.98c
                    493: 
                    494:   Revision 1.114  2006/02/26 12:57:58  brouard
                    495:   (Module): Some improvements in processing parameter
                    496:   filename with strsep.
                    497: 
                    498:   Revision 1.113  2006/02/24 14:20:24  brouard
                    499:   (Module): Memory leaks checks with valgrind and:
                    500:   datafile was not closed, some imatrix were not freed and on matrix
                    501:   allocation too.
                    502: 
                    503:   Revision 1.112  2006/01/30 09:55:26  brouard
                    504:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    505: 
                    506:   Revision 1.111  2006/01/25 20:38:18  brouard
                    507:   (Module): Lots of cleaning and bugs added (Gompertz)
                    508:   (Module): Comments can be added in data file. Missing date values
                    509:   can be a simple dot '.'.
                    510: 
                    511:   Revision 1.110  2006/01/25 00:51:50  brouard
                    512:   (Module): Lots of cleaning and bugs added (Gompertz)
                    513: 
                    514:   Revision 1.109  2006/01/24 19:37:15  brouard
                    515:   (Module): Comments (lines starting with a #) are allowed in data.
                    516: 
                    517:   Revision 1.108  2006/01/19 18:05:42  lievre
                    518:   Gnuplot problem appeared...
                    519:   To be fixed
                    520: 
                    521:   Revision 1.107  2006/01/19 16:20:37  brouard
                    522:   Test existence of gnuplot in imach path
                    523: 
                    524:   Revision 1.106  2006/01/19 13:24:36  brouard
                    525:   Some cleaning and links added in html output
                    526: 
                    527:   Revision 1.105  2006/01/05 20:23:19  lievre
                    528:   *** empty log message ***
                    529: 
                    530:   Revision 1.104  2005/09/30 16:11:43  lievre
                    531:   (Module): sump fixed, loop imx fixed, and simplifications.
                    532:   (Module): If the status is missing at the last wave but we know
                    533:   that the person is alive, then we can code his/her status as -2
                    534:   (instead of missing=-1 in earlier versions) and his/her
                    535:   contributions to the likelihood is 1 - Prob of dying from last
                    536:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    537:   the healthy state at last known wave). Version is 0.98
                    538: 
                    539:   Revision 1.103  2005/09/30 15:54:49  lievre
                    540:   (Module): sump fixed, loop imx fixed, and simplifications.
                    541: 
                    542:   Revision 1.102  2004/09/15 17:31:30  brouard
                    543:   Add the possibility to read data file including tab characters.
                    544: 
                    545:   Revision 1.101  2004/09/15 10:38:38  brouard
                    546:   Fix on curr_time
                    547: 
                    548:   Revision 1.100  2004/07/12 18:29:06  brouard
                    549:   Add version for Mac OS X. Just define UNIX in Makefile
                    550: 
                    551:   Revision 1.99  2004/06/05 08:57:40  brouard
                    552:   *** empty log message ***
                    553: 
                    554:   Revision 1.98  2004/05/16 15:05:56  brouard
                    555:   New version 0.97 . First attempt to estimate force of mortality
                    556:   directly from the data i.e. without the need of knowing the health
                    557:   state at each age, but using a Gompertz model: log u =a + b*age .
                    558:   This is the basic analysis of mortality and should be done before any
                    559:   other analysis, in order to test if the mortality estimated from the
                    560:   cross-longitudinal survey is different from the mortality estimated
                    561:   from other sources like vital statistic data.
                    562: 
                    563:   The same imach parameter file can be used but the option for mle should be -3.
                    564: 
1.133     brouard   565:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   566:   former routines in order to include the new code within the former code.
                    567: 
                    568:   The output is very simple: only an estimate of the intercept and of
                    569:   the slope with 95% confident intervals.
                    570: 
                    571:   Current limitations:
                    572:   A) Even if you enter covariates, i.e. with the
                    573:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    574:   B) There is no computation of Life Expectancy nor Life Table.
                    575: 
                    576:   Revision 1.97  2004/02/20 13:25:42  lievre
                    577:   Version 0.96d. Population forecasting command line is (temporarily)
                    578:   suppressed.
                    579: 
                    580:   Revision 1.96  2003/07/15 15:38:55  brouard
                    581:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    582:   rewritten within the same printf. Workaround: many printfs.
                    583: 
                    584:   Revision 1.95  2003/07/08 07:54:34  brouard
                    585:   * imach.c (Repository):
                    586:   (Repository): Using imachwizard code to output a more meaningful covariance
                    587:   matrix (cov(a12,c31) instead of numbers.
                    588: 
                    589:   Revision 1.94  2003/06/27 13:00:02  brouard
                    590:   Just cleaning
                    591: 
                    592:   Revision 1.93  2003/06/25 16:33:55  brouard
                    593:   (Module): On windows (cygwin) function asctime_r doesn't
                    594:   exist so I changed back to asctime which exists.
                    595:   (Module): Version 0.96b
                    596: 
                    597:   Revision 1.92  2003/06/25 16:30:45  brouard
                    598:   (Module): On windows (cygwin) function asctime_r doesn't
                    599:   exist so I changed back to asctime which exists.
                    600: 
                    601:   Revision 1.91  2003/06/25 15:30:29  brouard
                    602:   * imach.c (Repository): Duplicated warning errors corrected.
                    603:   (Repository): Elapsed time after each iteration is now output. It
                    604:   helps to forecast when convergence will be reached. Elapsed time
                    605:   is stamped in powell.  We created a new html file for the graphs
                    606:   concerning matrix of covariance. It has extension -cov.htm.
                    607: 
                    608:   Revision 1.90  2003/06/24 12:34:15  brouard
                    609:   (Module): Some bugs corrected for windows. Also, when
                    610:   mle=-1 a template is output in file "or"mypar.txt with the design
                    611:   of the covariance matrix to be input.
                    612: 
                    613:   Revision 1.89  2003/06/24 12:30:52  brouard
                    614:   (Module): Some bugs corrected for windows. Also, when
                    615:   mle=-1 a template is output in file "or"mypar.txt with the design
                    616:   of the covariance matrix to be input.
                    617: 
                    618:   Revision 1.88  2003/06/23 17:54:56  brouard
                    619:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    620: 
                    621:   Revision 1.87  2003/06/18 12:26:01  brouard
                    622:   Version 0.96
                    623: 
                    624:   Revision 1.86  2003/06/17 20:04:08  brouard
                    625:   (Module): Change position of html and gnuplot routines and added
                    626:   routine fileappend.
                    627: 
                    628:   Revision 1.85  2003/06/17 13:12:43  brouard
                    629:   * imach.c (Repository): Check when date of death was earlier that
                    630:   current date of interview. It may happen when the death was just
                    631:   prior to the death. In this case, dh was negative and likelihood
                    632:   was wrong (infinity). We still send an "Error" but patch by
                    633:   assuming that the date of death was just one stepm after the
                    634:   interview.
                    635:   (Repository): Because some people have very long ID (first column)
                    636:   we changed int to long in num[] and we added a new lvector for
                    637:   memory allocation. But we also truncated to 8 characters (left
                    638:   truncation)
                    639:   (Repository): No more line truncation errors.
                    640: 
                    641:   Revision 1.84  2003/06/13 21:44:43  brouard
                    642:   * imach.c (Repository): Replace "freqsummary" at a correct
                    643:   place. It differs from routine "prevalence" which may be called
                    644:   many times. Probs is memory consuming and must be used with
                    645:   parcimony.
                    646:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    647: 
                    648:   Revision 1.83  2003/06/10 13:39:11  lievre
                    649:   *** empty log message ***
                    650: 
                    651:   Revision 1.82  2003/06/05 15:57:20  brouard
                    652:   Add log in  imach.c and  fullversion number is now printed.
                    653: 
                    654: */
                    655: /*
                    656:    Interpolated Markov Chain
                    657: 
                    658:   Short summary of the programme:
                    659:   
1.227     brouard   660:   This program computes Healthy Life Expectancies or State-specific
                    661:   (if states aren't health statuses) Expectancies from
                    662:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    663: 
                    664:   -1- a first survey ("cross") where individuals from different ages
                    665:   are interviewed on their health status or degree of disability (in
                    666:   the case of a health survey which is our main interest)
                    667: 
                    668:   -2- at least a second wave of interviews ("longitudinal") which
                    669:   measure each change (if any) in individual health status.  Health
                    670:   expectancies are computed from the time spent in each health state
                    671:   according to a model. More health states you consider, more time is
                    672:   necessary to reach the Maximum Likelihood of the parameters involved
                    673:   in the model.  The simplest model is the multinomial logistic model
                    674:   where pij is the probability to be observed in state j at the second
                    675:   wave conditional to be observed in state i at the first
                    676:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    677:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    678:   have a more complex model than "constant and age", you should modify
                    679:   the program where the markup *Covariates have to be included here
                    680:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   681:   convergence.
                    682: 
                    683:   The advantage of this computer programme, compared to a simple
                    684:   multinomial logistic model, is clear when the delay between waves is not
                    685:   identical for each individual. Also, if a individual missed an
                    686:   intermediate interview, the information is lost, but taken into
                    687:   account using an interpolation or extrapolation.  
                    688: 
                    689:   hPijx is the probability to be observed in state i at age x+h
                    690:   conditional to the observed state i at age x. The delay 'h' can be
                    691:   split into an exact number (nh*stepm) of unobserved intermediate
                    692:   states. This elementary transition (by month, quarter,
                    693:   semester or year) is modelled as a multinomial logistic.  The hPx
                    694:   matrix is simply the matrix product of nh*stepm elementary matrices
                    695:   and the contribution of each individual to the likelihood is simply
                    696:   hPijx.
                    697: 
                    698:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   699:   of the life expectancies. It also computes the period (stable) prevalence.
                    700: 
                    701: Back prevalence and projections:
1.227     brouard   702: 
                    703:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    704:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    705:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    706:    mobilavproj)
                    707: 
                    708:     Computes the back prevalence limit for any combination of
                    709:     covariate values k at any age between ageminpar and agemaxpar and
                    710:     returns it in **bprlim. In the loops,
                    711: 
                    712:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    713:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    714: 
                    715:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   716:    Computes for any combination of covariates k and any age between bage and fage 
                    717:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    718:                        oldm=oldms;savm=savms;
1.227     brouard   719: 
                    720:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);
1.218     brouard   721:      Computes the transition matrix starting at age 'age' over
                    722:      'nhstepm*hstepm*stepm' months (i.e. until
                    723:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   724:      nhstepm*hstepm matrices. 
                    725: 
                    726:      Returns p3mat[i][j][h] after calling
                    727:      p3mat[i][j][h]=matprod2(newm,
                    728:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    729:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    730:      oldm);
1.226     brouard   731: 
                    732: Important routines
                    733: 
                    734: - func (or funcone), computes logit (pij) distinguishing
                    735:   o fixed variables (single or product dummies or quantitative);
                    736:   o varying variables by:
                    737:    (1) wave (single, product dummies, quantitative), 
                    738:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    739:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    740:        % varying dummy (not done) or quantitative (not done);
                    741: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    742:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    743: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    744:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    745:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   746: 
1.226     brouard   747: 
                    748:   
1.133     brouard   749:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    750:            Institut national d'études démographiques, Paris.
1.126     brouard   751:   This software have been partly granted by Euro-REVES, a concerted action
                    752:   from the European Union.
                    753:   It is copyrighted identically to a GNU software product, ie programme and
                    754:   software can be distributed freely for non commercial use. Latest version
                    755:   can be accessed at http://euroreves.ined.fr/imach .
                    756: 
                    757:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    758:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    759:   
                    760:   **********************************************************************/
                    761: /*
                    762:   main
                    763:   read parameterfile
                    764:   read datafile
                    765:   concatwav
                    766:   freqsummary
                    767:   if (mle >= 1)
                    768:     mlikeli
                    769:   print results files
                    770:   if mle==1 
                    771:      computes hessian
                    772:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    773:       begin-prev-date,...
                    774:   open gnuplot file
                    775:   open html file
1.145     brouard   776:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    777:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    778:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    779:     freexexit2 possible for memory heap.
                    780: 
                    781:   h Pij x                         | pij_nom  ficrestpij
                    782:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    783:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    784:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    785: 
                    786:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    787:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    788:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    789:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    790:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    791: 
1.126     brouard   792:   forecasting if prevfcast==1 prevforecast call prevalence()
                    793:   health expectancies
                    794:   Variance-covariance of DFLE
                    795:   prevalence()
                    796:    movingaverage()
                    797:   varevsij() 
                    798:   if popbased==1 varevsij(,popbased)
                    799:   total life expectancies
                    800:   Variance of period (stable) prevalence
                    801:  end
                    802: */
                    803: 
1.187     brouard   804: /* #define DEBUG */
                    805: /* #define DEBUGBRENT */
1.203     brouard   806: /* #define DEBUGLINMIN */
                    807: /* #define DEBUGHESS */
                    808: #define DEBUGHESSIJ
1.224     brouard   809: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   810: #define POWELL /* Instead of NLOPT */
1.224     brouard   811: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   812: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    813: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   814: 
                    815: #include <math.h>
                    816: #include <stdio.h>
                    817: #include <stdlib.h>
                    818: #include <string.h>
1.226     brouard   819: #include <ctype.h>
1.159     brouard   820: 
                    821: #ifdef _WIN32
                    822: #include <io.h>
1.172     brouard   823: #include <windows.h>
                    824: #include <tchar.h>
1.159     brouard   825: #else
1.126     brouard   826: #include <unistd.h>
1.159     brouard   827: #endif
1.126     brouard   828: 
                    829: #include <limits.h>
                    830: #include <sys/types.h>
1.171     brouard   831: 
                    832: #if defined(__GNUC__)
                    833: #include <sys/utsname.h> /* Doesn't work on Windows */
                    834: #endif
                    835: 
1.126     brouard   836: #include <sys/stat.h>
                    837: #include <errno.h>
1.159     brouard   838: /* extern int errno; */
1.126     brouard   839: 
1.157     brouard   840: /* #ifdef LINUX */
                    841: /* #include <time.h> */
                    842: /* #include "timeval.h" */
                    843: /* #else */
                    844: /* #include <sys/time.h> */
                    845: /* #endif */
                    846: 
1.126     brouard   847: #include <time.h>
                    848: 
1.136     brouard   849: #ifdef GSL
                    850: #include <gsl/gsl_errno.h>
                    851: #include <gsl/gsl_multimin.h>
                    852: #endif
                    853: 
1.167     brouard   854: 
1.162     brouard   855: #ifdef NLOPT
                    856: #include <nlopt.h>
                    857: typedef struct {
                    858:   double (* function)(double [] );
                    859: } myfunc_data ;
                    860: #endif
                    861: 
1.126     brouard   862: /* #include <libintl.h> */
                    863: /* #define _(String) gettext (String) */
                    864: 
1.141     brouard   865: #define MAXLINE 1024 /* Was 256. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   866: 
                    867: #define GNUPLOTPROGRAM "gnuplot"
                    868: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    869: #define FILENAMELENGTH 132
                    870: 
                    871: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    872: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    873: 
1.144     brouard   874: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    875: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   876: 
                    877: #define NINTERVMAX 8
1.144     brouard   878: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    879: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    880: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   881: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   882: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    883: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   884: #define MAXN 20000
1.144     brouard   885: #define YEARM 12. /**< Number of months per year */
1.218     brouard   886: /* #define AGESUP 130 */
                    887: #define AGESUP 150
                    888: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard   889: #define AGEBASE 40
1.194     brouard   890: #define AGEOVERFLOW 1.e20
1.164     brouard   891: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard   892: #ifdef _WIN32
                    893: #define DIRSEPARATOR '\\'
                    894: #define CHARSEPARATOR "\\"
                    895: #define ODIRSEPARATOR '/'
                    896: #else
1.126     brouard   897: #define DIRSEPARATOR '/'
                    898: #define CHARSEPARATOR "/"
                    899: #define ODIRSEPARATOR '\\'
                    900: #endif
                    901: 
1.234   ! brouard   902: /* $Id: imach.c,v 1.233 2016/08/23 07:40:50 brouard Exp $ */
1.126     brouard   903: /* $State: Exp $ */
1.196     brouard   904: #include "version.h"
                    905: char version[]=__IMACH_VERSION__;
1.224     brouard   906: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.234   ! brouard   907: char fullversion[]="$Revision: 1.233 $ $Date: 2016/08/23 07:40:50 $"; 
1.126     brouard   908: char strstart[80];
                    909: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard   910: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard   911: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard   912: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                    913: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                    914: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard   915: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                    916: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard   917: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                    918: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                    919: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard   920: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                    921: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard   922: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234   ! brouard   923: int nsd=0; /**< Total number of single dummy variables (output) */
        !           924: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard   925: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard   926: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard   927: int ntveff=0; /**< ntveff number of effective time varying variables */
                    928: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard   929: int cptcov=0; /* Working variable */
1.218     brouard   930: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard   931: int npar=NPARMAX;
                    932: int nlstate=2; /* Number of live states */
                    933: int ndeath=1; /* Number of dead states */
1.130     brouard   934: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard   935: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard   936: int popbased=0;
                    937: 
                    938: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard   939: int maxwav=0; /* Maxim number of waves */
                    940: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                    941: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                    942: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard   943:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard   944: int mle=1, weightopt=0;
1.126     brouard   945: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                    946: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                    947: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                    948:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard   949: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard   950: int selected(int kvar); /* Is covariate kvar selected for printing results */
                    951: 
1.130     brouard   952: double jmean=1; /* Mean space between 2 waves */
1.145     brouard   953: double **matprod2(); /* test */
1.126     brouard   954: double **oldm, **newm, **savm; /* Working pointers to matrices */
                    955: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard   956: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                    957: 
1.136     brouard   958: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard   959: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard   960: FILE *ficlog, *ficrespow;
1.130     brouard   961: int globpr=0; /* Global variable for printing or not */
1.126     brouard   962: double fretone; /* Only one call to likelihood */
1.130     brouard   963: long ipmx=0; /* Number of contributions */
1.126     brouard   964: double sw; /* Sum of weights */
                    965: char filerespow[FILENAMELENGTH];
                    966: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                    967: FILE *ficresilk;
                    968: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                    969: FILE *ficresprobmorprev;
                    970: FILE *fichtm, *fichtmcov; /* Html File */
                    971: FILE *ficreseij;
                    972: char filerese[FILENAMELENGTH];
                    973: FILE *ficresstdeij;
                    974: char fileresstde[FILENAMELENGTH];
                    975: FILE *ficrescveij;
                    976: char filerescve[FILENAMELENGTH];
                    977: FILE  *ficresvij;
                    978: char fileresv[FILENAMELENGTH];
                    979: FILE  *ficresvpl;
                    980: char fileresvpl[FILENAMELENGTH];
                    981: char title[MAXLINE];
1.234   ! brouard   982: char model[MAXLINE]; /**< The model line */
1.217     brouard   983: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard   984: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                    985: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                    986: char command[FILENAMELENGTH];
                    987: int  outcmd=0;
                    988: 
1.217     brouard   989: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard   990: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard   991: char filelog[FILENAMELENGTH]; /* Log file */
                    992: char filerest[FILENAMELENGTH];
                    993: char fileregp[FILENAMELENGTH];
                    994: char popfile[FILENAMELENGTH];
                    995: 
                    996: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                    997: 
1.157     brouard   998: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                    999: /* struct timezone tzp; */
                   1000: /* extern int gettimeofday(); */
                   1001: struct tm tml, *gmtime(), *localtime();
                   1002: 
                   1003: extern time_t time();
                   1004: 
                   1005: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1006: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1007: struct tm tm;
                   1008: 
1.126     brouard  1009: char strcurr[80], strfor[80];
                   1010: 
                   1011: char *endptr;
                   1012: long lval;
                   1013: double dval;
                   1014: 
                   1015: #define NR_END 1
                   1016: #define FREE_ARG char*
                   1017: #define FTOL 1.0e-10
                   1018: 
                   1019: #define NRANSI 
                   1020: #define ITMAX 200 
                   1021: 
                   1022: #define TOL 2.0e-4 
                   1023: 
                   1024: #define CGOLD 0.3819660 
                   1025: #define ZEPS 1.0e-10 
                   1026: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1027: 
                   1028: #define GOLD 1.618034 
                   1029: #define GLIMIT 100.0 
                   1030: #define TINY 1.0e-20 
                   1031: 
                   1032: static double maxarg1,maxarg2;
                   1033: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1034: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1035:   
                   1036: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1037: #define rint(a) floor(a+0.5)
1.166     brouard  1038: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1039: #define mytinydouble 1.0e-16
1.166     brouard  1040: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1041: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1042: /* static double dsqrarg; */
                   1043: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1044: static double sqrarg;
                   1045: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1046: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1047: int agegomp= AGEGOMP;
                   1048: 
                   1049: int imx; 
                   1050: int stepm=1;
                   1051: /* Stepm, step in month: minimum step interpolation*/
                   1052: 
                   1053: int estepm;
                   1054: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1055: 
                   1056: int m,nb;
                   1057: long *num;
1.197     brouard  1058: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1059: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1060:                   covariate for which somebody answered excluding 
                   1061:                   undefined. Usually 2: 0 and 1. */
                   1062: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1063:                             covariate for which somebody answered including 
                   1064:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1065: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1066: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1067: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1068: double *ageexmed,*agecens;
                   1069: double dateintmean=0;
                   1070: 
                   1071: double *weight;
                   1072: int **s; /* Status */
1.141     brouard  1073: double *agedc;
1.145     brouard  1074: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1075:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1076:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.225     brouard  1077: double **coqvar; /* Fixed quantitative covariate iqv */
                   1078: double ***cotvar; /* Time varying covariate itv */
                   1079: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1080: double  idx; 
                   1081: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234   ! brouard  1082: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
        !          1083: /*k          1  2   3   4     5    6    7     8    9 */
        !          1084: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
        !          1085: /* Tndvar[k]    1   2   3               4          5 */
        !          1086: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
        !          1087: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
        !          1088: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
        !          1089: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
        !          1090: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
        !          1091: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
        !          1092: /* Tprod[i]=k           4               7            */
        !          1093: /* Tage[i]=k                  5               8      */
        !          1094: /* */
        !          1095: /* Type                    */
        !          1096: /* V         1  2  3  4  5 */
        !          1097: /*           F  F  V  V  V */
        !          1098: /*           D  Q  D  D  Q */
        !          1099: /*                         */
        !          1100: int *TvarsD;
        !          1101: int *TvarsDind;
        !          1102: int *TvarsQ;
        !          1103: int *TvarsQind;
        !          1104: 
        !          1105: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1106: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1107: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1108: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1109: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1110: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1111: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1112: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1113: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1114: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1115: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1116: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1117: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1118: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1119: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1120: 
1.230     brouard  1121: int *Tvarsel; /**< Selected covariates for output */
                   1122: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1123: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1124: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1125: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.197     brouard  1126: int *Tage;
1.227     brouard  1127: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1128: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1129: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1130: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1131: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1132: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1133: int **Tvard;
                   1134: int *Tprod;/**< Gives the k position of the k1 product */
                   1135: int *Tposprod; /**< Gives the k1 product from the k position */
                   1136: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   1137:    if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
                   1138:    Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
                   1139: */
                   1140: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1141: double *lsurv, *lpop, *tpop;
                   1142: 
1.231     brouard  1143: #define FD 1; /* Fixed dummy covariate */
                   1144: #define FQ 2; /* Fixed quantitative covariate */
                   1145: #define FP 3; /* Fixed product covariate */
                   1146: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1147: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1148: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1149: #define VD 10; /* Varying dummy covariate */
                   1150: #define VQ 11; /* Varying quantitative covariate */
                   1151: #define VP 12; /* Varying product covariate */
                   1152: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1153: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1154: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1155: #define APFD 16; /* Age product * fixed dummy covariate */
                   1156: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1157: #define APVD 18; /* Age product * varying dummy covariate */
                   1158: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1159: 
                   1160: #define FTYPE 1; /* Fixed covariate */
                   1161: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1162: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1163: 
                   1164: struct kmodel{
                   1165:        int maintype; /* main type */
                   1166:        int subtype; /* subtype */
                   1167: };
                   1168: struct kmodel modell[NCOVMAX];
                   1169: 
1.143     brouard  1170: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1171: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1172: 
                   1173: /**************** split *************************/
                   1174: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1175: {
                   1176:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1177:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1178:   */ 
                   1179:   char *ss;                            /* pointer */
1.186     brouard  1180:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1181: 
                   1182:   l1 = strlen(path );                  /* length of path */
                   1183:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1184:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1185:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1186:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1187:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1188:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1189:     /* get current working directory */
                   1190:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1191: #ifdef WIN32
                   1192:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1193: #else
                   1194:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1195: #endif
1.126     brouard  1196:       return( GLOCK_ERROR_GETCWD );
                   1197:     }
                   1198:     /* got dirc from getcwd*/
                   1199:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1200:   } else {                             /* strip directory from path */
1.126     brouard  1201:     ss++;                              /* after this, the filename */
                   1202:     l2 = strlen( ss );                 /* length of filename */
                   1203:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1204:     strcpy( name, ss );                /* save file name */
                   1205:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1206:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1207:     printf(" DIRC2 = %s \n",dirc);
                   1208:   }
                   1209:   /* We add a separator at the end of dirc if not exists */
                   1210:   l1 = strlen( dirc );                 /* length of directory */
                   1211:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1212:     dirc[l1] =  DIRSEPARATOR;
                   1213:     dirc[l1+1] = 0; 
                   1214:     printf(" DIRC3 = %s \n",dirc);
                   1215:   }
                   1216:   ss = strrchr( name, '.' );           /* find last / */
                   1217:   if (ss >0){
                   1218:     ss++;
                   1219:     strcpy(ext,ss);                    /* save extension */
                   1220:     l1= strlen( name);
                   1221:     l2= strlen(ss)+1;
                   1222:     strncpy( finame, name, l1-l2);
                   1223:     finame[l1-l2]= 0;
                   1224:   }
                   1225: 
                   1226:   return( 0 );                         /* we're done */
                   1227: }
                   1228: 
                   1229: 
                   1230: /******************************************/
                   1231: 
                   1232: void replace_back_to_slash(char *s, char*t)
                   1233: {
                   1234:   int i;
                   1235:   int lg=0;
                   1236:   i=0;
                   1237:   lg=strlen(t);
                   1238:   for(i=0; i<= lg; i++) {
                   1239:     (s[i] = t[i]);
                   1240:     if (t[i]== '\\') s[i]='/';
                   1241:   }
                   1242: }
                   1243: 
1.132     brouard  1244: char *trimbb(char *out, char *in)
1.137     brouard  1245: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1246:   char *s;
                   1247:   s=out;
                   1248:   while (*in != '\0'){
1.137     brouard  1249:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1250:       in++;
                   1251:     }
                   1252:     *out++ = *in++;
                   1253:   }
                   1254:   *out='\0';
                   1255:   return s;
                   1256: }
                   1257: 
1.187     brouard  1258: /* char *substrchaine(char *out, char *in, char *chain) */
                   1259: /* { */
                   1260: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1261: /*   char *s, *t; */
                   1262: /*   t=in;s=out; */
                   1263: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1264: /*     *out++ = *in++; */
                   1265: /*   } */
                   1266: 
                   1267: /*   /\* *in matches *chain *\/ */
                   1268: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1269: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1270: /*   } */
                   1271: /*   in--; chain--; */
                   1272: /*   while ( (*in != '\0')){ */
                   1273: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1274: /*     *out++ = *in++; */
                   1275: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1276: /*   } */
                   1277: /*   *out='\0'; */
                   1278: /*   out=s; */
                   1279: /*   return out; */
                   1280: /* } */
                   1281: char *substrchaine(char *out, char *in, char *chain)
                   1282: {
                   1283:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1284:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1285: 
                   1286:   char *strloc;
                   1287: 
                   1288:   strcpy (out, in); 
                   1289:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1290:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1291:   if(strloc != NULL){ 
                   1292:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1293:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1294:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1295:   }
                   1296:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1297:   return out;
                   1298: }
                   1299: 
                   1300: 
1.145     brouard  1301: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1302: {
1.187     brouard  1303:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1304:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1305:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1306:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1307:   */
1.160     brouard  1308:   char *s, *t;
1.145     brouard  1309:   t=in;s=in;
                   1310:   while ((*in != occ) && (*in != '\0')){
                   1311:     *alocc++ = *in++;
                   1312:   }
                   1313:   if( *in == occ){
                   1314:     *(alocc)='\0';
                   1315:     s=++in;
                   1316:   }
                   1317:  
                   1318:   if (s == t) {/* occ not found */
                   1319:     *(alocc-(in-s))='\0';
                   1320:     in=s;
                   1321:   }
                   1322:   while ( *in != '\0'){
                   1323:     *blocc++ = *in++;
                   1324:   }
                   1325: 
                   1326:   *blocc='\0';
                   1327:   return t;
                   1328: }
1.137     brouard  1329: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1330: {
1.187     brouard  1331:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1332:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1333:      gives blocc="abcdef2ghi" and alocc="j".
                   1334:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1335:   */
                   1336:   char *s, *t;
                   1337:   t=in;s=in;
                   1338:   while (*in != '\0'){
                   1339:     while( *in == occ){
                   1340:       *blocc++ = *in++;
                   1341:       s=in;
                   1342:     }
                   1343:     *blocc++ = *in++;
                   1344:   }
                   1345:   if (s == t) /* occ not found */
                   1346:     *(blocc-(in-s))='\0';
                   1347:   else
                   1348:     *(blocc-(in-s)-1)='\0';
                   1349:   in=s;
                   1350:   while ( *in != '\0'){
                   1351:     *alocc++ = *in++;
                   1352:   }
                   1353: 
                   1354:   *alocc='\0';
                   1355:   return s;
                   1356: }
                   1357: 
1.126     brouard  1358: int nbocc(char *s, char occ)
                   1359: {
                   1360:   int i,j=0;
                   1361:   int lg=20;
                   1362:   i=0;
                   1363:   lg=strlen(s);
                   1364:   for(i=0; i<= lg; i++) {
1.234   ! brouard  1365:     if  (s[i] == occ ) j++;
1.126     brouard  1366:   }
                   1367:   return j;
                   1368: }
                   1369: 
1.137     brouard  1370: /* void cutv(char *u,char *v, char*t, char occ) */
                   1371: /* { */
                   1372: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1373: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1374: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1375: /*   int i,lg,j,p=0; */
                   1376: /*   i=0; */
                   1377: /*   lg=strlen(t); */
                   1378: /*   for(j=0; j<=lg-1; j++) { */
                   1379: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1380: /*   } */
1.126     brouard  1381: 
1.137     brouard  1382: /*   for(j=0; j<p; j++) { */
                   1383: /*     (u[j] = t[j]); */
                   1384: /*   } */
                   1385: /*      u[p]='\0'; */
1.126     brouard  1386: 
1.137     brouard  1387: /*    for(j=0; j<= lg; j++) { */
                   1388: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1389: /*   } */
                   1390: /* } */
1.126     brouard  1391: 
1.160     brouard  1392: #ifdef _WIN32
                   1393: char * strsep(char **pp, const char *delim)
                   1394: {
                   1395:   char *p, *q;
                   1396:          
                   1397:   if ((p = *pp) == NULL)
                   1398:     return 0;
                   1399:   if ((q = strpbrk (p, delim)) != NULL)
                   1400:   {
                   1401:     *pp = q + 1;
                   1402:     *q = '\0';
                   1403:   }
                   1404:   else
                   1405:     *pp = 0;
                   1406:   return p;
                   1407: }
                   1408: #endif
                   1409: 
1.126     brouard  1410: /********************** nrerror ********************/
                   1411: 
                   1412: void nrerror(char error_text[])
                   1413: {
                   1414:   fprintf(stderr,"ERREUR ...\n");
                   1415:   fprintf(stderr,"%s\n",error_text);
                   1416:   exit(EXIT_FAILURE);
                   1417: }
                   1418: /*********************** vector *******************/
                   1419: double *vector(int nl, int nh)
                   1420: {
                   1421:   double *v;
                   1422:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1423:   if (!v) nrerror("allocation failure in vector");
                   1424:   return v-nl+NR_END;
                   1425: }
                   1426: 
                   1427: /************************ free vector ******************/
                   1428: void free_vector(double*v, int nl, int nh)
                   1429: {
                   1430:   free((FREE_ARG)(v+nl-NR_END));
                   1431: }
                   1432: 
                   1433: /************************ivector *******************************/
                   1434: int *ivector(long nl,long nh)
                   1435: {
                   1436:   int *v;
                   1437:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1438:   if (!v) nrerror("allocation failure in ivector");
                   1439:   return v-nl+NR_END;
                   1440: }
                   1441: 
                   1442: /******************free ivector **************************/
                   1443: void free_ivector(int *v, long nl, long nh)
                   1444: {
                   1445:   free((FREE_ARG)(v+nl-NR_END));
                   1446: }
                   1447: 
                   1448: /************************lvector *******************************/
                   1449: long *lvector(long nl,long nh)
                   1450: {
                   1451:   long *v;
                   1452:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1453:   if (!v) nrerror("allocation failure in ivector");
                   1454:   return v-nl+NR_END;
                   1455: }
                   1456: 
                   1457: /******************free lvector **************************/
                   1458: void free_lvector(long *v, long nl, long nh)
                   1459: {
                   1460:   free((FREE_ARG)(v+nl-NR_END));
                   1461: }
                   1462: 
                   1463: /******************* imatrix *******************************/
                   1464: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1465:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1466: { 
                   1467:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1468:   int **m; 
                   1469:   
                   1470:   /* allocate pointers to rows */ 
                   1471:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1472:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1473:   m += NR_END; 
                   1474:   m -= nrl; 
                   1475:   
                   1476:   
                   1477:   /* allocate rows and set pointers to them */ 
                   1478:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1479:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1480:   m[nrl] += NR_END; 
                   1481:   m[nrl] -= ncl; 
                   1482:   
                   1483:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1484:   
                   1485:   /* return pointer to array of pointers to rows */ 
                   1486:   return m; 
                   1487: } 
                   1488: 
                   1489: /****************** free_imatrix *************************/
                   1490: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1491:       int **m;
                   1492:       long nch,ncl,nrh,nrl; 
                   1493:      /* free an int matrix allocated by imatrix() */ 
                   1494: { 
                   1495:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1496:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1497: } 
                   1498: 
                   1499: /******************* matrix *******************************/
                   1500: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1501: {
                   1502:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1503:   double **m;
                   1504: 
                   1505:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1506:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1507:   m += NR_END;
                   1508:   m -= nrl;
                   1509: 
                   1510:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1511:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1512:   m[nrl] += NR_END;
                   1513:   m[nrl] -= ncl;
                   1514: 
                   1515:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1516:   return m;
1.145     brouard  1517:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1518: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1519: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1520:    */
                   1521: }
                   1522: 
                   1523: /*************************free matrix ************************/
                   1524: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1525: {
                   1526:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1527:   free((FREE_ARG)(m+nrl-NR_END));
                   1528: }
                   1529: 
                   1530: /******************* ma3x *******************************/
                   1531: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1532: {
                   1533:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1534:   double ***m;
                   1535: 
                   1536:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1537:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1538:   m += NR_END;
                   1539:   m -= nrl;
                   1540: 
                   1541:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1542:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1543:   m[nrl] += NR_END;
                   1544:   m[nrl] -= ncl;
                   1545: 
                   1546:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1547: 
                   1548:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1549:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1550:   m[nrl][ncl] += NR_END;
                   1551:   m[nrl][ncl] -= nll;
                   1552:   for (j=ncl+1; j<=nch; j++) 
                   1553:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1554:   
                   1555:   for (i=nrl+1; i<=nrh; i++) {
                   1556:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1557:     for (j=ncl+1; j<=nch; j++) 
                   1558:       m[i][j]=m[i][j-1]+nlay;
                   1559:   }
                   1560:   return m; 
                   1561:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1562:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1563:   */
                   1564: }
                   1565: 
                   1566: /*************************free ma3x ************************/
                   1567: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1568: {
                   1569:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1570:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1571:   free((FREE_ARG)(m+nrl-NR_END));
                   1572: }
                   1573: 
                   1574: /*************** function subdirf ***********/
                   1575: char *subdirf(char fileres[])
                   1576: {
                   1577:   /* Caution optionfilefiname is hidden */
                   1578:   strcpy(tmpout,optionfilefiname);
                   1579:   strcat(tmpout,"/"); /* Add to the right */
                   1580:   strcat(tmpout,fileres);
                   1581:   return tmpout;
                   1582: }
                   1583: 
                   1584: /*************** function subdirf2 ***********/
                   1585: char *subdirf2(char fileres[], char *preop)
                   1586: {
                   1587:   
                   1588:   /* Caution optionfilefiname is hidden */
                   1589:   strcpy(tmpout,optionfilefiname);
                   1590:   strcat(tmpout,"/");
                   1591:   strcat(tmpout,preop);
                   1592:   strcat(tmpout,fileres);
                   1593:   return tmpout;
                   1594: }
                   1595: 
                   1596: /*************** function subdirf3 ***********/
                   1597: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1598: {
                   1599:   
                   1600:   /* Caution optionfilefiname is hidden */
                   1601:   strcpy(tmpout,optionfilefiname);
                   1602:   strcat(tmpout,"/");
                   1603:   strcat(tmpout,preop);
                   1604:   strcat(tmpout,preop2);
                   1605:   strcat(tmpout,fileres);
                   1606:   return tmpout;
                   1607: }
1.213     brouard  1608:  
                   1609: /*************** function subdirfext ***********/
                   1610: char *subdirfext(char fileres[], char *preop, char *postop)
                   1611: {
                   1612:   
                   1613:   strcpy(tmpout,preop);
                   1614:   strcat(tmpout,fileres);
                   1615:   strcat(tmpout,postop);
                   1616:   return tmpout;
                   1617: }
1.126     brouard  1618: 
1.213     brouard  1619: /*************** function subdirfext3 ***********/
                   1620: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1621: {
                   1622:   
                   1623:   /* Caution optionfilefiname is hidden */
                   1624:   strcpy(tmpout,optionfilefiname);
                   1625:   strcat(tmpout,"/");
                   1626:   strcat(tmpout,preop);
                   1627:   strcat(tmpout,fileres);
                   1628:   strcat(tmpout,postop);
                   1629:   return tmpout;
                   1630: }
                   1631:  
1.162     brouard  1632: char *asc_diff_time(long time_sec, char ascdiff[])
                   1633: {
                   1634:   long sec_left, days, hours, minutes;
                   1635:   days = (time_sec) / (60*60*24);
                   1636:   sec_left = (time_sec) % (60*60*24);
                   1637:   hours = (sec_left) / (60*60) ;
                   1638:   sec_left = (sec_left) %(60*60);
                   1639:   minutes = (sec_left) /60;
                   1640:   sec_left = (sec_left) % (60);
                   1641:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1642:   return ascdiff;
                   1643: }
                   1644: 
1.126     brouard  1645: /***************** f1dim *************************/
                   1646: extern int ncom; 
                   1647: extern double *pcom,*xicom;
                   1648: extern double (*nrfunc)(double []); 
                   1649:  
                   1650: double f1dim(double x) 
                   1651: { 
                   1652:   int j; 
                   1653:   double f;
                   1654:   double *xt; 
                   1655:  
                   1656:   xt=vector(1,ncom); 
                   1657:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1658:   f=(*nrfunc)(xt); 
                   1659:   free_vector(xt,1,ncom); 
                   1660:   return f; 
                   1661: } 
                   1662: 
                   1663: /*****************brent *************************/
                   1664: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1665: {
                   1666:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1667:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1668:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1669:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1670:    * returned function value. 
                   1671:   */
1.126     brouard  1672:   int iter; 
                   1673:   double a,b,d,etemp;
1.159     brouard  1674:   double fu=0,fv,fw,fx;
1.164     brouard  1675:   double ftemp=0.;
1.126     brouard  1676:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1677:   double e=0.0; 
                   1678:  
                   1679:   a=(ax < cx ? ax : cx); 
                   1680:   b=(ax > cx ? ax : cx); 
                   1681:   x=w=v=bx; 
                   1682:   fw=fv=fx=(*f)(x); 
                   1683:   for (iter=1;iter<=ITMAX;iter++) { 
                   1684:     xm=0.5*(a+b); 
                   1685:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1686:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1687:     printf(".");fflush(stdout);
                   1688:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1689: #ifdef DEBUGBRENT
1.126     brouard  1690:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1691:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1692:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1693: #endif
                   1694:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1695:       *xmin=x; 
                   1696:       return fx; 
                   1697:     } 
                   1698:     ftemp=fu;
                   1699:     if (fabs(e) > tol1) { 
                   1700:       r=(x-w)*(fx-fv); 
                   1701:       q=(x-v)*(fx-fw); 
                   1702:       p=(x-v)*q-(x-w)*r; 
                   1703:       q=2.0*(q-r); 
                   1704:       if (q > 0.0) p = -p; 
                   1705:       q=fabs(q); 
                   1706:       etemp=e; 
                   1707:       e=d; 
                   1708:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1709:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1710:       else { 
1.224     brouard  1711:                                d=p/q; 
                   1712:                                u=x+d; 
                   1713:                                if (u-a < tol2 || b-u < tol2) 
                   1714:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1715:       } 
                   1716:     } else { 
                   1717:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1718:     } 
                   1719:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1720:     fu=(*f)(u); 
                   1721:     if (fu <= fx) { 
                   1722:       if (u >= x) a=x; else b=x; 
                   1723:       SHFT(v,w,x,u) 
1.183     brouard  1724:       SHFT(fv,fw,fx,fu) 
                   1725:     } else { 
                   1726:       if (u < x) a=u; else b=u; 
                   1727:       if (fu <= fw || w == x) { 
1.224     brouard  1728:                                v=w; 
                   1729:                                w=u; 
                   1730:                                fv=fw; 
                   1731:                                fw=fu; 
1.183     brouard  1732:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1733:                                v=u; 
                   1734:                                fv=fu; 
1.183     brouard  1735:       } 
                   1736:     } 
1.126     brouard  1737:   } 
                   1738:   nrerror("Too many iterations in brent"); 
                   1739:   *xmin=x; 
                   1740:   return fx; 
                   1741: } 
                   1742: 
                   1743: /****************** mnbrak ***********************/
                   1744: 
                   1745: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1746:            double (*func)(double)) 
1.183     brouard  1747: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1748: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1749: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1750: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1751:    */
1.126     brouard  1752:   double ulim,u,r,q, dum;
                   1753:   double fu; 
1.187     brouard  1754: 
                   1755:   double scale=10.;
                   1756:   int iterscale=0;
                   1757: 
                   1758:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1759:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1760: 
                   1761: 
                   1762:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1763:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1764:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1765:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1766:   /* } */
                   1767: 
1.126     brouard  1768:   if (*fb > *fa) { 
                   1769:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1770:     SHFT(dum,*fb,*fa,dum) 
                   1771:   } 
1.126     brouard  1772:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1773:   *fc=(*func)(*cx); 
1.183     brouard  1774: #ifdef DEBUG
1.224     brouard  1775:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1776:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1777: #endif
1.224     brouard  1778:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1779:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1780:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1781:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1782:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1783:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1784:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1785:       fu=(*func)(u); 
1.163     brouard  1786: #ifdef DEBUG
                   1787:       /* f(x)=A(x-u)**2+f(u) */
                   1788:       double A, fparabu; 
                   1789:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1790:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1791:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1792:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1793:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1794:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1795:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1796:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1797: #endif 
1.184     brouard  1798: #ifdef MNBRAKORIGINAL
1.183     brouard  1799: #else
1.191     brouard  1800: /*       if (fu > *fc) { */
                   1801: /* #ifdef DEBUG */
                   1802: /*       printf("mnbrak4  fu > fc \n"); */
                   1803: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1804: /* #endif */
                   1805: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1806: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1807: /*     dum=u; /\* Shifting c and u *\/ */
                   1808: /*     u = *cx; */
                   1809: /*     *cx = dum; */
                   1810: /*     dum = fu; */
                   1811: /*     fu = *fc; */
                   1812: /*     *fc =dum; */
                   1813: /*       } else { /\* end *\/ */
                   1814: /* #ifdef DEBUG */
                   1815: /*       printf("mnbrak3  fu < fc \n"); */
                   1816: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1817: /* #endif */
                   1818: /*     dum=u; /\* Shifting c and u *\/ */
                   1819: /*     u = *cx; */
                   1820: /*     *cx = dum; */
                   1821: /*     dum = fu; */
                   1822: /*     fu = *fc; */
                   1823: /*     *fc =dum; */
                   1824: /*       } */
1.224     brouard  1825: #ifdef DEBUGMNBRAK
                   1826:                 double A, fparabu; 
                   1827:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1828:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1829:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1830:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1831: #endif
1.191     brouard  1832:       dum=u; /* Shifting c and u */
                   1833:       u = *cx;
                   1834:       *cx = dum;
                   1835:       dum = fu;
                   1836:       fu = *fc;
                   1837:       *fc =dum;
1.183     brouard  1838: #endif
1.162     brouard  1839:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1840: #ifdef DEBUG
1.224     brouard  1841:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1842:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1843: #endif
1.126     brouard  1844:       fu=(*func)(u); 
                   1845:       if (fu < *fc) { 
1.183     brouard  1846: #ifdef DEBUG
1.224     brouard  1847:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1848:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1849: #endif
                   1850:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1851:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1852: #ifdef DEBUG
                   1853:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1854: #endif
                   1855:       } 
1.162     brouard  1856:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1857: #ifdef DEBUG
1.224     brouard  1858:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1859:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1860: #endif
1.126     brouard  1861:       u=ulim; 
                   1862:       fu=(*func)(u); 
1.183     brouard  1863:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1864: #ifdef DEBUG
1.224     brouard  1865:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1866:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1867: #endif
1.126     brouard  1868:       u=(*cx)+GOLD*(*cx-*bx); 
                   1869:       fu=(*func)(u); 
1.224     brouard  1870: #ifdef DEBUG
                   1871:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1872:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1873: #endif
1.183     brouard  1874:     } /* end tests */
1.126     brouard  1875:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  1876:     SHFT(*fa,*fb,*fc,fu) 
                   1877: #ifdef DEBUG
1.224     brouard  1878:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   1879:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  1880: #endif
                   1881:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  1882: } 
                   1883: 
                   1884: /*************** linmin ************************/
1.162     brouard  1885: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   1886: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   1887: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   1888: the value of func at the returned location p . This is actually all accomplished by calling the
                   1889: routines mnbrak and brent .*/
1.126     brouard  1890: int ncom; 
                   1891: double *pcom,*xicom;
                   1892: double (*nrfunc)(double []); 
                   1893:  
1.224     brouard  1894: #ifdef LINMINORIGINAL
1.126     brouard  1895: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  1896: #else
                   1897: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   1898: #endif
1.126     brouard  1899: { 
                   1900:   double brent(double ax, double bx, double cx, 
                   1901:               double (*f)(double), double tol, double *xmin); 
                   1902:   double f1dim(double x); 
                   1903:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   1904:              double *fc, double (*func)(double)); 
                   1905:   int j; 
                   1906:   double xx,xmin,bx,ax; 
                   1907:   double fx,fb,fa;
1.187     brouard  1908: 
1.203     brouard  1909: #ifdef LINMINORIGINAL
                   1910: #else
                   1911:   double scale=10., axs, xxs; /* Scale added for infinity */
                   1912: #endif
                   1913:   
1.126     brouard  1914:   ncom=n; 
                   1915:   pcom=vector(1,n); 
                   1916:   xicom=vector(1,n); 
                   1917:   nrfunc=func; 
                   1918:   for (j=1;j<=n;j++) { 
                   1919:     pcom[j]=p[j]; 
1.202     brouard  1920:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  1921:   } 
1.187     brouard  1922: 
1.203     brouard  1923: #ifdef LINMINORIGINAL
                   1924:   xx=1.;
                   1925: #else
                   1926:   axs=0.0;
                   1927:   xxs=1.;
                   1928:   do{
                   1929:     xx= xxs;
                   1930: #endif
1.187     brouard  1931:     ax=0.;
                   1932:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   1933:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   1934:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   1935:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   1936:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   1937:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   1938:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  1939: #ifdef LINMINORIGINAL
                   1940: #else
                   1941:     if (fx != fx){
1.224     brouard  1942:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   1943:                        printf("|");
                   1944:                        fprintf(ficlog,"|");
1.203     brouard  1945: #ifdef DEBUGLINMIN
1.224     brouard  1946:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  1947: #endif
                   1948:     }
1.224     brouard  1949:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  1950: #endif
                   1951:   
1.191     brouard  1952: #ifdef DEBUGLINMIN
                   1953:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  1954:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  1955: #endif
1.224     brouard  1956: #ifdef LINMINORIGINAL
                   1957: #else
                   1958:        if(fb == fx){ /* Flat function in the direction */
                   1959:                xmin=xx;
                   1960:     *flat=1;
                   1961:        }else{
                   1962:     *flat=0;
                   1963: #endif
                   1964:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  1965:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   1966:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   1967:   /* fmin = f(p[j] + xmin * xi[j]) */
                   1968:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   1969:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  1970: #ifdef DEBUG
1.224     brouard  1971:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   1972:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   1973: #endif
                   1974: #ifdef LINMINORIGINAL
                   1975: #else
                   1976:                        }
1.126     brouard  1977: #endif
1.191     brouard  1978: #ifdef DEBUGLINMIN
                   1979:   printf("linmin end ");
1.202     brouard  1980:   fprintf(ficlog,"linmin end ");
1.191     brouard  1981: #endif
1.126     brouard  1982:   for (j=1;j<=n;j++) { 
1.203     brouard  1983: #ifdef LINMINORIGINAL
                   1984:     xi[j] *= xmin; 
                   1985: #else
                   1986: #ifdef DEBUGLINMIN
                   1987:     if(xxs <1.0)
                   1988:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   1989: #endif
                   1990:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   1991: #ifdef DEBUGLINMIN
                   1992:     if(xxs <1.0)
                   1993:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   1994: #endif
                   1995: #endif
1.187     brouard  1996:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  1997:   } 
1.191     brouard  1998: #ifdef DEBUGLINMIN
1.203     brouard  1999:   printf("\n");
1.191     brouard  2000:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2001:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2002:   for (j=1;j<=n;j++) { 
1.202     brouard  2003:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2004:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2005:     if(j % ncovmodel == 0){
1.191     brouard  2006:       printf("\n");
1.202     brouard  2007:       fprintf(ficlog,"\n");
                   2008:     }
1.191     brouard  2009:   }
1.203     brouard  2010: #else
1.191     brouard  2011: #endif
1.126     brouard  2012:   free_vector(xicom,1,n); 
                   2013:   free_vector(pcom,1,n); 
                   2014: } 
                   2015: 
                   2016: 
                   2017: /*************** powell ************************/
1.162     brouard  2018: /*
                   2019: Minimization of a function func of n variables. Input consists of an initial starting point
                   2020: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2021: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2022: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2023: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2024: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2025:  */
1.224     brouard  2026: #ifdef LINMINORIGINAL
                   2027: #else
                   2028:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2029:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2030: #endif
1.126     brouard  2031: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2032:            double (*func)(double [])) 
                   2033: { 
1.224     brouard  2034: #ifdef LINMINORIGINAL
                   2035:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2036:              double (*func)(double [])); 
1.224     brouard  2037: #else 
                   2038:  void linmin(double p[], double xi[], int n, double *fret, 
                   2039:                                                 double (*func)(double []),int *flat); 
                   2040: #endif
1.126     brouard  2041:   int i,ibig,j; 
                   2042:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2043:   double directest;
1.126     brouard  2044:   double fp,fptt;
                   2045:   double *xits;
                   2046:   int niterf, itmp;
1.224     brouard  2047: #ifdef LINMINORIGINAL
                   2048: #else
                   2049: 
                   2050:   flatdir=ivector(1,n); 
                   2051:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2052: #endif
1.126     brouard  2053: 
                   2054:   pt=vector(1,n); 
                   2055:   ptt=vector(1,n); 
                   2056:   xit=vector(1,n); 
                   2057:   xits=vector(1,n); 
                   2058:   *fret=(*func)(p); 
                   2059:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2060:   rcurr_time = time(NULL);  
1.126     brouard  2061:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2062:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2063:     ibig=0; 
                   2064:     del=0.0; 
1.157     brouard  2065:     rlast_time=rcurr_time;
                   2066:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2067:     rcurr_time = time(NULL);  
                   2068:     curr_time = *localtime(&rcurr_time);
                   2069:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2070:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2071: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2072:     for (i=1;i<=n;i++) {
1.126     brouard  2073:       printf(" %d %.12f",i, p[i]);
                   2074:       fprintf(ficlog," %d %.12lf",i, p[i]);
                   2075:       fprintf(ficrespow," %.12lf", p[i]);
                   2076:     }
                   2077:     printf("\n");
                   2078:     fprintf(ficlog,"\n");
                   2079:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2080:     if(*iter <=3){
1.157     brouard  2081:       tml = *localtime(&rcurr_time);
                   2082:       strcpy(strcurr,asctime(&tml));
                   2083:       rforecast_time=rcurr_time; 
1.126     brouard  2084:       itmp = strlen(strcurr);
                   2085:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.224     brouard  2086:                                strcurr[itmp-1]='\0';
1.162     brouard  2087:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2088:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2089:       for(niterf=10;niterf<=30;niterf+=10){
1.224     brouard  2090:                                rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2091:                                forecast_time = *localtime(&rforecast_time);
                   2092:                                strcpy(strfor,asctime(&forecast_time));
                   2093:                                itmp = strlen(strfor);
                   2094:                                if(strfor[itmp-1]=='\n')
                   2095:                                        strfor[itmp-1]='\0';
                   2096:                                printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2097:                                fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2098:       }
                   2099:     }
1.187     brouard  2100:     for (i=1;i<=n;i++) { /* For each direction i */
                   2101:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2102:       fptt=(*fret); 
                   2103: #ifdef DEBUG
1.203     brouard  2104:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2105:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2106: #endif
1.203     brouard  2107:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2108:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2109: #ifdef LINMINORIGINAL
1.188     brouard  2110:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2111: #else
                   2112:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2113:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2114: #endif
                   2115:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2116:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2117:                                /* because that direction will be replaced unless the gain del is small */
                   2118:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2119:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2120:                                /* with the new direction. */
                   2121:                                del=fabs(fptt-(*fret)); 
                   2122:                                ibig=i; 
1.126     brouard  2123:       } 
                   2124: #ifdef DEBUG
                   2125:       printf("%d %.12e",i,(*fret));
                   2126:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2127:       for (j=1;j<=n;j++) {
1.224     brouard  2128:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2129:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2130:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2131:       }
                   2132:       for(j=1;j<=n;j++) {
1.225     brouard  2133:                                printf(" p(%d)=%.12e",j,p[j]);
                   2134:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2135:       }
                   2136:       printf("\n");
                   2137:       fprintf(ficlog,"\n");
                   2138: #endif
1.187     brouard  2139:     } /* end loop on each direction i */
                   2140:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2141:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2142:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2143:       for(j=1;j<=n;j++) {
1.225     brouard  2144:                                if(flatdir[j] >0){
                   2145:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2146:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2147:                                }
                   2148:                                /* printf("\n"); */
                   2149:                                /* fprintf(ficlog,"\n"); */
                   2150:                        }
1.182     brouard  2151:     if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /* Did we reach enough precision? */
1.188     brouard  2152:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2153:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2154:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2155:       /* decreased of more than 3.84  */
                   2156:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2157:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2158:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2159:                        
1.188     brouard  2160:       /* Starting the program with initial values given by a former maximization will simply change */
                   2161:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2162:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2163:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2164: #ifdef DEBUG
                   2165:       int k[2],l;
                   2166:       k[0]=1;
                   2167:       k[1]=-1;
                   2168:       printf("Max: %.12e",(*func)(p));
                   2169:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2170:       for (j=1;j<=n;j++) {
                   2171:        printf(" %.12e",p[j]);
                   2172:        fprintf(ficlog," %.12e",p[j]);
                   2173:       }
                   2174:       printf("\n");
                   2175:       fprintf(ficlog,"\n");
                   2176:       for(l=0;l<=1;l++) {
                   2177:        for (j=1;j<=n;j++) {
                   2178:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2179:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2180:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2181:        }
                   2182:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2183:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2184:       }
                   2185: #endif
                   2186: 
1.224     brouard  2187: #ifdef LINMINORIGINAL
                   2188: #else
                   2189:       free_ivector(flatdir,1,n); 
                   2190: #endif
1.126     brouard  2191:       free_vector(xit,1,n); 
                   2192:       free_vector(xits,1,n); 
                   2193:       free_vector(ptt,1,n); 
                   2194:       free_vector(pt,1,n); 
                   2195:       return; 
1.192     brouard  2196:     } /* enough precision */ 
1.126     brouard  2197:     if (*iter == ITMAX) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2198:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2199:       ptt[j]=2.0*p[j]-pt[j]; 
                   2200:       xit[j]=p[j]-pt[j]; 
                   2201:       pt[j]=p[j]; 
                   2202:     } 
1.181     brouard  2203:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2204: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2205:                if (*iter <=4) {
1.225     brouard  2206: #else
                   2207: #endif
1.224     brouard  2208: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2209: #else
1.161     brouard  2210:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2211: #endif
1.162     brouard  2212:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2213:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2214:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2215:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2216:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2217:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2218:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2219:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2220:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2221:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2222:       /* mu² and del² are equal when f3=f1 */
                   2223:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2224:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2225:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2226:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2227: #ifdef NRCORIGINAL
                   2228:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2229: #else
                   2230:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2231:       t= t- del*SQR(fp-fptt);
1.183     brouard  2232: #endif
1.202     brouard  2233:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2234: #ifdef DEBUG
1.181     brouard  2235:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2236:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2237:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2238:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2239:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2240:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2241:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2242:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2243: #endif
1.183     brouard  2244: #ifdef POWELLORIGINAL
                   2245:       if (t < 0.0) { /* Then we use it for new direction */
                   2246: #else
1.182     brouard  2247:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2248:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2249:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2250:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2251:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2252:       } 
1.181     brouard  2253:       if (directest < 0.0) { /* Then we use it for new direction */
                   2254: #endif
1.191     brouard  2255: #ifdef DEBUGLINMIN
1.234   ! brouard  2256:        printf("Before linmin in direction P%d-P0\n",n);
        !          2257:        for (j=1;j<=n;j++) {
        !          2258:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
        !          2259:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
        !          2260:          if(j % ncovmodel == 0){
        !          2261:            printf("\n");
        !          2262:            fprintf(ficlog,"\n");
        !          2263:          }
        !          2264:        }
1.224     brouard  2265: #endif
                   2266: #ifdef LINMINORIGINAL
1.234   ! brouard  2267:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2268: #else
1.234   ! brouard  2269:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
        !          2270:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2271: #endif
1.234   ! brouard  2272:        
1.191     brouard  2273: #ifdef DEBUGLINMIN
1.234   ! brouard  2274:        for (j=1;j<=n;j++) { 
        !          2275:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
        !          2276:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
        !          2277:          if(j % ncovmodel == 0){
        !          2278:            printf("\n");
        !          2279:            fprintf(ficlog,"\n");
        !          2280:          }
        !          2281:        }
1.224     brouard  2282: #endif
1.234   ! brouard  2283:        for (j=1;j<=n;j++) { 
        !          2284:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
        !          2285:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
        !          2286:        }
1.224     brouard  2287: #ifdef LINMINORIGINAL
                   2288: #else
1.234   ! brouard  2289:        for (j=1, flatd=0;j<=n;j++) {
        !          2290:          if(flatdir[j]>0)
        !          2291:            flatd++;
        !          2292:        }
        !          2293:        if(flatd >0){
        !          2294:          printf("%d flat directions\n",flatd);
        !          2295:          fprintf(ficlog,"%d flat directions\n",flatd);
        !          2296:          for (j=1;j<=n;j++) { 
        !          2297:            if(flatdir[j]>0){
        !          2298:              printf("%d ",j);
        !          2299:              fprintf(ficlog,"%d ",j);
        !          2300:            }
        !          2301:          }
        !          2302:          printf("\n");
        !          2303:          fprintf(ficlog,"\n");
        !          2304:        }
1.191     brouard  2305: #endif
1.234   ! brouard  2306:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
        !          2307:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
        !          2308:        
1.126     brouard  2309: #ifdef DEBUG
1.234   ! brouard  2310:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
        !          2311:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
        !          2312:        for(j=1;j<=n;j++){
        !          2313:          printf(" %lf",xit[j]);
        !          2314:          fprintf(ficlog," %lf",xit[j]);
        !          2315:        }
        !          2316:        printf("\n");
        !          2317:        fprintf(ficlog,"\n");
1.126     brouard  2318: #endif
1.192     brouard  2319:       } /* end of t or directest negative */
1.224     brouard  2320: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2321: #else
1.234   ! brouard  2322:       } /* end if (fptt < fp)  */
1.192     brouard  2323: #endif
1.225     brouard  2324: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234   ! brouard  2325:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2326: #else
1.224     brouard  2327: #endif
1.234   ! brouard  2328:                } /* loop iteration */ 
1.126     brouard  2329: } 
1.234   ! brouard  2330:   
1.126     brouard  2331: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234   ! brouard  2332:   
1.203     brouard  2333: double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij)
1.234   ! brouard  2334:   {
        !          2335:     /* Computes the prevalence limit in each live state at age x and for covariate combiation ij by left multiplying the unit
        !          2336:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2337:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2338:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2339:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2340:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2341:   /* Initial matrix pimij */
                   2342:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2343:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2344:   /*  0,                   0                  , 1} */
                   2345:   /*
                   2346:    * and after some iteration: */
                   2347:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2348:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2349:   /*  0,                   0                  , 1} */
                   2350:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2351:   /* {0.51571254859325999, 0.4842874514067399, */
                   2352:   /*  0.51326036147820708, 0.48673963852179264} */
                   2353:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234   ! brouard  2354:     
1.126     brouard  2355:   int i, ii,j,k;
1.209     brouard  2356:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2357:   /* double **matprod2(); */ /* test */
1.218     brouard  2358:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2359:   double **newm;
1.209     brouard  2360:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2361:   int ncvloop=0;
1.169     brouard  2362:   
1.209     brouard  2363:   min=vector(1,nlstate);
                   2364:   max=vector(1,nlstate);
                   2365:   meandiff=vector(1,nlstate);
                   2366: 
1.218     brouard  2367:        /* Starting with matrix unity */
1.126     brouard  2368:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2369:     for (j=1;j<=nlstate+ndeath;j++){
                   2370:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2371:     }
1.169     brouard  2372:   
                   2373:   cov[1]=1.;
                   2374:   
                   2375:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2376:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2377:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2378:     ncvloop++;
1.126     brouard  2379:     newm=savm;
                   2380:     /* Covariates have to be included here again */
1.138     brouard  2381:     cov[2]=agefin;
1.187     brouard  2382:     if(nagesqr==1)
                   2383:       cov[3]= agefin*agefin;;
1.234   ! brouard  2384:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
        !          2385:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
        !          2386:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
        !          2387:       printf("prevalim ij=%d k=%d TvarsD[%d]=%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k));
        !          2388:     }
        !          2389:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
        !          2390:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
        !          2391:       /* cov[2+nagesqr+TvarsQind[k]]=qselvar[k]; */
        !          2392:       printf("prevalim ij=%d k=%d  TvarsQind[%d]=%d \n",ij,k,k,TvarsQind[k]);
1.138     brouard  2393:     }
1.186     brouard  2394:     /*wrong? for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
1.200     brouard  2395:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]*cov[2]; */
1.234   ! brouard  2396:     for (k=1; k<=cptcovage;k++){
        !          2397:       if(Dummy[Tvar[Tage[k]]]){
        !          2398:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
        !          2399:       } else{
        !          2400:        ;
        !          2401:        /* cov[2+nagesqr+Tage[k]]=qselvar[k]; */
        !          2402:       }
        !          2403:       printf("prevalim Age ij=%d k=%d  Tage[%d]=%d \n",ij,k,k,Tage[k]);
        !          2404:     }
        !          2405:     for (k=1; k<=cptcovprod;k++){ /*  */
        !          2406:       printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=%d, Tvard[%d][2]=%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]);
1.200     brouard  2407:       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
1.234   ! brouard  2408:     }
1.138     brouard  2409:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2410:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2411:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2412:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2413:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2414:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2415:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2416:     
1.126     brouard  2417:     savm=oldm;
                   2418:     oldm=newm;
1.209     brouard  2419: 
                   2420:     for(j=1; j<=nlstate; j++){
                   2421:       max[j]=0.;
                   2422:       min[j]=1.;
                   2423:     }
                   2424:     for(i=1;i<=nlstate;i++){
                   2425:       sumnew=0;
                   2426:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2427:       for(j=1; j<=nlstate; j++){ 
                   2428:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2429:        max[j]=FMAX(max[j],prlim[i][j]);
                   2430:        min[j]=FMIN(min[j],prlim[i][j]);
                   2431:       }
                   2432:     }
                   2433: 
1.126     brouard  2434:     maxmax=0.;
1.209     brouard  2435:     for(j=1; j<=nlstate; j++){
                   2436:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2437:       maxmax=FMAX(maxmax,meandiff[j]);
                   2438:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2439:     } /* j loop */
1.203     brouard  2440:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2441:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2442:     if(maxmax < ftolpl){
1.209     brouard  2443:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2444:       free_vector(min,1,nlstate);
                   2445:       free_vector(max,1,nlstate);
                   2446:       free_vector(meandiff,1,nlstate);
1.126     brouard  2447:       return prlim;
                   2448:     }
1.169     brouard  2449:   } /* age loop */
1.208     brouard  2450:     /* After some age loop it doesn't converge */
1.209     brouard  2451:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2452: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2453:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2454:   free_vector(min,1,nlstate);
                   2455:   free_vector(max,1,nlstate);
                   2456:   free_vector(meandiff,1,nlstate);
1.208     brouard  2457:   
1.169     brouard  2458:   return prlim; /* should not reach here */
1.126     brouard  2459: }
                   2460: 
1.217     brouard  2461: 
                   2462:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2463: 
1.218     brouard  2464:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2465:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2466:  double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij)
1.217     brouard  2467: {
1.218     brouard  2468:   /* Computes the prevalence limit in each live state at age x and covariate ij by left multiplying the unit
1.217     brouard  2469:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2470:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2471:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2472:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2473:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2474:   /* Initial matrix pimij */
                   2475:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2476:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2477:   /*  0,                   0                  , 1} */
                   2478:   /*
                   2479:    * and after some iteration: */
                   2480:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2481:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2482:   /*  0,                   0                  , 1} */
                   2483:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2484:   /* {0.51571254859325999, 0.4842874514067399, */
                   2485:   /*  0.51326036147820708, 0.48673963852179264} */
                   2486:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2487: 
                   2488:   int i, ii,j,k;
                   2489:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2490:   /* double **matprod2(); */ /* test */
                   2491:   double **out, cov[NCOVMAX+1], **bmij();
                   2492:   double **newm;
1.218     brouard  2493:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2494:   double        **oldm, **savm;  /* for use */
                   2495: 
1.217     brouard  2496:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2497:   int ncvloop=0;
                   2498:   
                   2499:   min=vector(1,nlstate);
                   2500:   max=vector(1,nlstate);
                   2501:   meandiff=vector(1,nlstate);
                   2502: 
1.218     brouard  2503:        dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2504:        oldm=oldms; savm=savms;
                   2505: 
                   2506:        /* Starting with matrix unity */
                   2507:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   2508:                for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2509:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2510:     }
                   2511:   
                   2512:   cov[1]=1.;
                   2513:   
                   2514:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2515:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2516:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2517:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2518:     ncvloop++;
1.218     brouard  2519:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2520:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2521:     /* Covariates have to be included here again */
                   2522:     cov[2]=agefin;
                   2523:     if(nagesqr==1)
                   2524:       cov[3]= agefin*agefin;;
                   2525:     for (k=1; k<=cptcovn;k++) {
                   2526:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
                   2527:       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   2528:       /* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); */
                   2529:     }
                   2530:     /*wrong? for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   2531:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]*cov[2]; */
                   2532:     for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2];
                   2533:     for (k=1; k<=cptcovprod;k++) /* Useless */
                   2534:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
                   2535:       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2536:     
                   2537:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2538:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2539:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2540:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2541:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2542:                /* ij should be linked to the correct index of cov */
                   2543:                /* age and covariate values ij are in 'cov', but we need to pass
                   2544:                 * ij for the observed prevalence at age and status and covariate
                   2545:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2546:                 */
                   2547:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2548:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2549:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.217     brouard  2550:     savm=oldm;
                   2551:     oldm=newm;
                   2552:     for(j=1; j<=nlstate; j++){
                   2553:       max[j]=0.;
                   2554:       min[j]=1.;
                   2555:     }
                   2556:     for(j=1; j<=nlstate; j++){ 
                   2557:       for(i=1;i<=nlstate;i++){
1.234   ! brouard  2558:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
        !          2559:        bprlim[i][j]= newm[i][j];
        !          2560:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
        !          2561:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2562:       }
                   2563:     }
1.218     brouard  2564:                
1.217     brouard  2565:     maxmax=0.;
                   2566:     for(i=1; i<=nlstate; i++){
                   2567:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2568:       maxmax=FMAX(maxmax,meandiff[i]);
                   2569:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
                   2570:     } /* j loop */
                   2571:     *ncvyear= -( (int)age- (int)agefin);
1.218     brouard  2572:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear);*/
1.217     brouard  2573:     if(maxmax < ftolpl){
1.220     brouard  2574:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2575:       free_vector(min,1,nlstate);
                   2576:       free_vector(max,1,nlstate);
                   2577:       free_vector(meandiff,1,nlstate);
                   2578:       return bprlim;
                   2579:     }
                   2580:   } /* age loop */
                   2581:     /* After some age loop it doesn't converge */
                   2582:   printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
                   2583: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2584:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2585:   free_vector(min,1,nlstate);
                   2586:   free_vector(max,1,nlstate);
                   2587:   free_vector(meandiff,1,nlstate);
                   2588:   
                   2589:   return bprlim; /* should not reach here */
                   2590: }
                   2591: 
1.126     brouard  2592: /*************** transition probabilities ***************/ 
                   2593: 
                   2594: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2595: {
1.138     brouard  2596:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2597:      computes the probability to be observed in state j being in state i by appying the
                   2598:      model to the ncovmodel covariates (including constant and age).
                   2599:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2600:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2601:      ncth covariate in the global vector x is given by the formula:
                   2602:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2603:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2604:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2605:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2606:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2607:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2608:   */
                   2609:   double s1, lnpijopii;
1.126     brouard  2610:   /*double t34;*/
1.164     brouard  2611:   int i,j, nc, ii, jj;
1.126     brouard  2612: 
1.223     brouard  2613:   for(i=1; i<= nlstate; i++){
                   2614:     for(j=1; j<i;j++){
                   2615:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2616:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2617:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2618:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2619:       }
                   2620:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2621:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2622:     }
                   2623:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2624:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2625:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2626:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2627:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2628:       }
                   2629:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2630:     }
                   2631:   }
1.218     brouard  2632:   
1.223     brouard  2633:   for(i=1; i<= nlstate; i++){
                   2634:     s1=0;
                   2635:     for(j=1; j<i; j++){
                   2636:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2637:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2638:     }
                   2639:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2640:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2641:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2642:     }
                   2643:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2644:     ps[i][i]=1./(s1+1.);
                   2645:     /* Computing other pijs */
                   2646:     for(j=1; j<i; j++)
                   2647:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2648:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2649:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2650:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2651:   } /* end i */
1.218     brouard  2652:   
1.223     brouard  2653:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2654:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2655:       ps[ii][jj]=0;
                   2656:       ps[ii][ii]=1;
                   2657:     }
                   2658:   }
1.218     brouard  2659:   
                   2660:   
1.223     brouard  2661:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2662:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2663:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2664:   /*   } */
                   2665:   /*   printf("\n "); */
                   2666:   /* } */
                   2667:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2668:   /*
                   2669:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2670:                goto end;*/
1.223     brouard  2671:   return ps;
1.126     brouard  2672: }
                   2673: 
1.218     brouard  2674: /*************** backward transition probabilities ***************/ 
                   2675: 
                   2676:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2677: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2678:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2679: {
1.222     brouard  2680:   /* Computes the backward probability at age agefin and covariate ij
                   2681:    * and returns in **ps as well as **bmij.
                   2682:    */
1.218     brouard  2683:   int i, ii, j,k;
1.222     brouard  2684:   
                   2685:   double **out, **pmij();
                   2686:   double sumnew=0.;
1.218     brouard  2687:   double agefin;
1.222     brouard  2688:   
                   2689:   double **dnewm, **dsavm, **doldm;
                   2690:   double **bbmij;
                   2691:   
1.218     brouard  2692:   doldm=ddoldms; /* global pointers */
1.222     brouard  2693:   dnewm=ddnewms;
                   2694:   dsavm=ddsavms;
                   2695:   
                   2696:   agefin=cov[2];
                   2697:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
                   2698:      the observed prevalence (with this covariate ij) */
                   2699:   dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate);
                   2700:   /* We do have the matrix Px in savm  and we need pij */
                   2701:   for (j=1;j<=nlstate+ndeath;j++){
                   2702:     sumnew=0.; /* w1 p11 + w2 p21 only on live states */
                   2703:     for (ii=1;ii<=nlstate;ii++){
                   2704:       sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij];
                   2705:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
                   2706:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2707:       if(sumnew >= 1.e-10){
                   2708:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
                   2709:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2710:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
                   2711:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2712:        /* }else */
                   2713:        doldm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2714:       }else{
                   2715:        printf("ii=%d, i=%d, doldm=%lf dsavm=%lf, probs=%lf, sumnew=%lf,agefin=%d\n",ii,j,doldm[ii][j],dsavm[ii][j],prevacurrent[(int)agefin][ii][ij],sumnew, (int)agefin);
                   2716:       }
                   2717:     } /*End ii */
                   2718:   } /* End j, At the end doldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2719:   /* left Product of this diag matrix by dsavm=Px (newm=dsavm*doldm) */
                   2720:   bbmij=matprod2(dnewm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, doldm); /* Bug Valgrind */
                   2721:   /* dsavm=doldm; /\* dsavm is now diag [1/(w_1p1i+w_2 p2i)] but can be overwritten*\/ */
                   2722:   /* doldm=dnewm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2723:   /* dnewm=dsavm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2724:   /* left Product of this matrix by diag matrix of prevalences (savm) */
                   2725:   for (j=1;j<=nlstate+ndeath;j++){
                   2726:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2727:       dsavm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij] : 0.0);
                   2728:     }
                   2729:   } /* End j, At the end oldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2730:   ps=matprod2(doldm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dnewm); /* Bug Valgrind */
                   2731:   /* newm or out is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
                   2732:   /* end bmij */
                   2733:   return ps; 
1.218     brouard  2734: }
1.217     brouard  2735: /*************** transition probabilities ***************/ 
                   2736: 
1.218     brouard  2737: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2738: {
                   2739:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2740:      computes the probability to be observed in state j being in state i by appying the
                   2741:      model to the ncovmodel covariates (including constant and age).
                   2742:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2743:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2744:      ncth covariate in the global vector x is given by the formula:
                   2745:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2746:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2747:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2748:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2749:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2750:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2751:   */
                   2752:   double s1, lnpijopii;
                   2753:   /*double t34;*/
                   2754:   int i,j, nc, ii, jj;
                   2755: 
1.234   ! brouard  2756:   for(i=1; i<= nlstate; i++){
        !          2757:     for(j=1; j<i;j++){
        !          2758:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
        !          2759:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
        !          2760:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
        !          2761:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
        !          2762:       }
        !          2763:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
        !          2764:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
        !          2765:     }
        !          2766:     for(j=i+1; j<=nlstate+ndeath;j++){
        !          2767:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
        !          2768:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
        !          2769:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
        !          2770:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
        !          2771:       }
        !          2772:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
        !          2773:     }
        !          2774:   }
        !          2775:   
        !          2776:   for(i=1; i<= nlstate; i++){
        !          2777:     s1=0;
        !          2778:     for(j=1; j<i; j++){
        !          2779:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
        !          2780:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
        !          2781:     }
        !          2782:     for(j=i+1; j<=nlstate+ndeath; j++){
        !          2783:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
        !          2784:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
        !          2785:     }
        !          2786:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
        !          2787:     ps[i][i]=1./(s1+1.);
        !          2788:     /* Computing other pijs */
        !          2789:     for(j=1; j<i; j++)
        !          2790:       ps[i][j]= exp(ps[i][j])*ps[i][i];
        !          2791:     for(j=i+1; j<=nlstate+ndeath; j++)
        !          2792:       ps[i][j]= exp(ps[i][j])*ps[i][i];
        !          2793:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
        !          2794:   } /* end i */
        !          2795:   
        !          2796:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
        !          2797:     for(jj=1; jj<= nlstate+ndeath; jj++){
        !          2798:       ps[ii][jj]=0;
        !          2799:       ps[ii][ii]=1;
        !          2800:     }
        !          2801:   }
        !          2802:   /* Added for backcast */ /* Transposed matrix too */
        !          2803:   for(jj=1; jj<= nlstate+ndeath; jj++){
        !          2804:     s1=0.;
        !          2805:     for(ii=1; ii<= nlstate+ndeath; ii++){
        !          2806:       s1+=ps[ii][jj];
        !          2807:     }
        !          2808:     for(ii=1; ii<= nlstate; ii++){
        !          2809:       ps[ii][jj]=ps[ii][jj]/s1;
        !          2810:     }
        !          2811:   }
        !          2812:   /* Transposition */
        !          2813:   for(jj=1; jj<= nlstate+ndeath; jj++){
        !          2814:     for(ii=jj; ii<= nlstate+ndeath; ii++){
        !          2815:       s1=ps[ii][jj];
        !          2816:       ps[ii][jj]=ps[jj][ii];
        !          2817:       ps[jj][ii]=s1;
        !          2818:     }
        !          2819:   }
        !          2820:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
        !          2821:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
        !          2822:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
        !          2823:   /*   } */
        !          2824:   /*   printf("\n "); */
        !          2825:   /* } */
        !          2826:   /* printf("\n ");printf("%lf ",cov[2]);*/
        !          2827:   /*
        !          2828:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
        !          2829:     goto end;*/
        !          2830:   return ps;
1.217     brouard  2831: }
                   2832: 
                   2833: 
1.126     brouard  2834: /**************** Product of 2 matrices ******************/
                   2835: 
1.145     brouard  2836: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  2837: {
                   2838:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   2839:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   2840:   /* in, b, out are matrice of pointers which should have been initialized 
                   2841:      before: only the contents of out is modified. The function returns
                   2842:      a pointer to pointers identical to out */
1.145     brouard  2843:   int i, j, k;
1.126     brouard  2844:   for(i=nrl; i<= nrh; i++)
1.145     brouard  2845:     for(k=ncolol; k<=ncoloh; k++){
                   2846:       out[i][k]=0.;
                   2847:       for(j=ncl; j<=nch; j++)
                   2848:        out[i][k] +=in[i][j]*b[j][k];
                   2849:     }
1.126     brouard  2850:   return out;
                   2851: }
                   2852: 
                   2853: 
                   2854: /************* Higher Matrix Product ***************/
                   2855: 
                   2856: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij )
                   2857: {
1.218     brouard  2858:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  2859:      'nhstepm*hstepm*stepm' months (i.e. until
                   2860:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   2861:      nhstepm*hstepm matrices. 
                   2862:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   2863:      (typically every 2 years instead of every month which is too big 
                   2864:      for the memory).
                   2865:      Model is determined by parameters x and covariates have to be 
                   2866:      included manually here. 
                   2867: 
                   2868:      */
                   2869: 
                   2870:   int i, j, d, h, k;
1.131     brouard  2871:   double **out, cov[NCOVMAX+1];
1.126     brouard  2872:   double **newm;
1.187     brouard  2873:   double agexact;
1.214     brouard  2874:   double agebegin, ageend;
1.126     brouard  2875: 
                   2876:   /* Hstepm could be zero and should return the unit matrix */
                   2877:   for (i=1;i<=nlstate+ndeath;i++)
                   2878:     for (j=1;j<=nlstate+ndeath;j++){
                   2879:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   2880:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   2881:     }
                   2882:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2883:   for(h=1; h <=nhstepm; h++){
                   2884:     for(d=1; d <=hstepm; d++){
                   2885:       newm=savm;
                   2886:       /* Covariates have to be included here again */
                   2887:       cov[1]=1.;
1.214     brouard  2888:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  2889:       cov[2]=agexact;
                   2890:       if(nagesqr==1)
1.227     brouard  2891:        cov[3]= agexact*agexact;
1.131     brouard  2892:       for (k=1; k<=cptcovn;k++) 
1.227     brouard  2893:        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   2894:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.186     brouard  2895:       for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
1.227     brouard  2896:        /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   2897:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2898:       /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
1.145     brouard  2899:       for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
1.227     brouard  2900:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2901:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
                   2902:       
                   2903:       
1.126     brouard  2904:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   2905:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  2906:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  2907:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   2908:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  2909:       /* if((int)age == 70){ */
                   2910:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   2911:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   2912:       /*         printf("%d pmmij ",i); */
                   2913:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2914:       /*           printf("%f ",pmmij[i][j]); */
                   2915:       /*         } */
                   2916:       /*         printf(" oldm "); */
                   2917:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2918:       /*           printf("%f ",oldm[i][j]); */
                   2919:       /*         } */
                   2920:       /*         printf("\n"); */
                   2921:       /*       } */
                   2922:       /* } */
1.126     brouard  2923:       savm=oldm;
                   2924:       oldm=newm;
                   2925:     }
                   2926:     for(i=1; i<=nlstate+ndeath; i++)
                   2927:       for(j=1;j<=nlstate+ndeath;j++) {
1.218     brouard  2928:                                po[i][j][h]=newm[i][j];
                   2929:                                /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  2930:       }
1.128     brouard  2931:     /*printf("h=%d ",h);*/
1.126     brouard  2932:   } /* end h */
1.218     brouard  2933:        /*     printf("\n H=%d \n",h); */
1.126     brouard  2934:   return po;
                   2935: }
                   2936: 
1.217     brouard  2937: /************* Higher Back Matrix Product ***************/
1.218     brouard  2938: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.222     brouard  2939: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij )
1.217     brouard  2940: {
1.218     brouard  2941:   /* Computes the transition matrix starting at age 'age' over
1.217     brouard  2942:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  2943:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   2944:      nhstepm*hstepm matrices.
                   2945:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   2946:      (typically every 2 years instead of every month which is too big
1.217     brouard  2947:      for the memory).
1.218     brouard  2948:      Model is determined by parameters x and covariates have to be
                   2949:      included manually here.
1.217     brouard  2950: 
1.222     brouard  2951:   */
1.217     brouard  2952: 
                   2953:   int i, j, d, h, k;
                   2954:   double **out, cov[NCOVMAX+1];
                   2955:   double **newm;
                   2956:   double agexact;
                   2957:   double agebegin, ageend;
1.222     brouard  2958:   double **oldm, **savm;
1.217     brouard  2959: 
1.222     brouard  2960:   oldm=oldms;savm=savms;
1.217     brouard  2961:   /* Hstepm could be zero and should return the unit matrix */
                   2962:   for (i=1;i<=nlstate+ndeath;i++)
                   2963:     for (j=1;j<=nlstate+ndeath;j++){
                   2964:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   2965:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   2966:     }
                   2967:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2968:   for(h=1; h <=nhstepm; h++){
                   2969:     for(d=1; d <=hstepm; d++){
                   2970:       newm=savm;
                   2971:       /* Covariates have to be included here again */
                   2972:       cov[1]=1.;
                   2973:       agexact=age-((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
                   2974:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   2975:       cov[2]=agexact;
                   2976:       if(nagesqr==1)
1.222     brouard  2977:        cov[3]= agexact*agexact;
1.218     brouard  2978:       for (k=1; k<=cptcovn;k++)
1.222     brouard  2979:        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   2980:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.217     brouard  2981:       for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
1.222     brouard  2982:        /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   2983:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2984:       /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
1.217     brouard  2985:       for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
1.222     brouard  2986:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2987:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
1.218     brouard  2988:                        
                   2989:                        
1.217     brouard  2990:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   2991:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  2992:       /* Careful transposed matrix */
1.222     brouard  2993:       /* age is in cov[2] */
1.218     brouard  2994:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  2995:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  2996:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  2997:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  2998:       /* if((int)age == 70){ */
                   2999:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3000:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3001:       /*         printf("%d pmmij ",i); */
                   3002:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3003:       /*           printf("%f ",pmmij[i][j]); */
                   3004:       /*         } */
                   3005:       /*         printf(" oldm "); */
                   3006:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3007:       /*           printf("%f ",oldm[i][j]); */
                   3008:       /*         } */
                   3009:       /*         printf("\n"); */
                   3010:       /*       } */
                   3011:       /* } */
                   3012:       savm=oldm;
                   3013:       oldm=newm;
                   3014:     }
                   3015:     for(i=1; i<=nlstate+ndeath; i++)
                   3016:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3017:        po[i][j][h]=newm[i][j];
                   3018:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.217     brouard  3019:       }
                   3020:     /*printf("h=%d ",h);*/
                   3021:   } /* end h */
1.222     brouard  3022:   /*     printf("\n H=%d \n",h); */
1.217     brouard  3023:   return po;
                   3024: }
                   3025: 
                   3026: 
1.162     brouard  3027: #ifdef NLOPT
                   3028:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3029:   double fret;
                   3030:   double *xt;
                   3031:   int j;
                   3032:   myfunc_data *d2 = (myfunc_data *) pd;
                   3033: /* xt = (p1-1); */
                   3034:   xt=vector(1,n); 
                   3035:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3036: 
                   3037:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3038:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3039:   printf("Function = %.12lf ",fret);
                   3040:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3041:   printf("\n");
                   3042:  free_vector(xt,1,n);
                   3043:   return fret;
                   3044: }
                   3045: #endif
1.126     brouard  3046: 
                   3047: /*************** log-likelihood *************/
                   3048: double func( double *x)
                   3049: {
1.226     brouard  3050:   int i, ii, j, k, mi, d, kk;
                   3051:   int ioffset=0;
                   3052:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3053:   double **out;
                   3054:   double lli; /* Individual log likelihood */
                   3055:   int s1, s2;
1.228     brouard  3056:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3057:   double bbh, survp;
                   3058:   long ipmx;
                   3059:   double agexact;
                   3060:   /*extern weight */
                   3061:   /* We are differentiating ll according to initial status */
                   3062:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3063:   /*for(i=1;i<imx;i++) 
                   3064:     printf(" %d\n",s[4][i]);
                   3065:   */
1.162     brouard  3066: 
1.226     brouard  3067:   ++countcallfunc;
1.162     brouard  3068: 
1.226     brouard  3069:   cov[1]=1.;
1.126     brouard  3070: 
1.226     brouard  3071:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3072:   ioffset=0;
1.226     brouard  3073:   if(mle==1){
                   3074:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3075:       /* Computes the values of the ncovmodel covariates of the model
                   3076:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3077:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3078:         to be observed in j being in i according to the model.
                   3079:       */
                   3080:       ioffset=2+nagesqr+cptcovage;
1.233     brouard  3081:    /* Fixed */
1.234   ! brouard  3082:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
        !          3083:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
        !          3084:       }
1.226     brouard  3085:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3086:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3087:         has been calculated etc */
                   3088:       /* For an individual i, wav[i] gives the number of effective waves */
                   3089:       /* We compute the contribution to Likelihood of each effective transition
                   3090:         mw[mi][i] is real wave of the mi th effectve wave */
                   3091:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3092:         s2=s[mw[mi+1][i]][i];
                   3093:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3094:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3095:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3096:       */
                   3097:       for(mi=1; mi<= wav[i]-1; mi++){
1.234   ! brouard  3098:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
        !          3099:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i];
        !          3100:        }
        !          3101:        for (ii=1;ii<=nlstate+ndeath;ii++)
        !          3102:          for (j=1;j<=nlstate+ndeath;j++){
        !          3103:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
        !          3104:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
        !          3105:          }
        !          3106:        for(d=0; d<dh[mi][i]; d++){
        !          3107:          newm=savm;
        !          3108:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
        !          3109:          cov[2]=agexact;
        !          3110:          if(nagesqr==1)
        !          3111:            cov[3]= agexact*agexact;  /* Should be changed here */
        !          3112:          for (kk=1; kk<=cptcovage;kk++) {
        !          3113:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
        !          3114:          }
        !          3115:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
        !          3116:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
        !          3117:          savm=oldm;
        !          3118:          oldm=newm;
        !          3119:        } /* end mult */
        !          3120:        
        !          3121:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
        !          3122:        /* But now since version 0.9 we anticipate for bias at large stepm.
        !          3123:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
        !          3124:         * (in months) between two waves is not a multiple of stepm, we rounded to 
        !          3125:         * the nearest (and in case of equal distance, to the lowest) interval but now
        !          3126:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
        !          3127:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
        !          3128:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3129:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3130:                                 * -stepm/2 to stepm/2 .
                   3131:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3132:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3133:                                 */
1.234   ! brouard  3134:        s1=s[mw[mi][i]][i];
        !          3135:        s2=s[mw[mi+1][i]][i];
        !          3136:        bbh=(double)bh[mi][i]/(double)stepm; 
        !          3137:        /* bias bh is positive if real duration
        !          3138:         * is higher than the multiple of stepm and negative otherwise.
        !          3139:         */
        !          3140:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
        !          3141:        if( s2 > nlstate){ 
        !          3142:          /* i.e. if s2 is a death state and if the date of death is known 
        !          3143:             then the contribution to the likelihood is the probability to 
        !          3144:             die between last step unit time and current  step unit time, 
        !          3145:             which is also equal to probability to die before dh 
        !          3146:             minus probability to die before dh-stepm . 
        !          3147:             In version up to 0.92 likelihood was computed
        !          3148:             as if date of death was unknown. Death was treated as any other
        !          3149:             health state: the date of the interview describes the actual state
        !          3150:             and not the date of a change in health state. The former idea was
        !          3151:             to consider that at each interview the state was recorded
        !          3152:             (healthy, disable or death) and IMaCh was corrected; but when we
        !          3153:             introduced the exact date of death then we should have modified
        !          3154:             the contribution of an exact death to the likelihood. This new
        !          3155:             contribution is smaller and very dependent of the step unit
        !          3156:             stepm. It is no more the probability to die between last interview
        !          3157:             and month of death but the probability to survive from last
        !          3158:             interview up to one month before death multiplied by the
        !          3159:             probability to die within a month. Thanks to Chris
        !          3160:             Jackson for correcting this bug.  Former versions increased
        !          3161:             mortality artificially. The bad side is that we add another loop
        !          3162:             which slows down the processing. The difference can be up to 10%
        !          3163:             lower mortality.
        !          3164:          */
        !          3165:          /* If, at the beginning of the maximization mostly, the
        !          3166:             cumulative probability or probability to be dead is
        !          3167:             constant (ie = 1) over time d, the difference is equal to
        !          3168:             0.  out[s1][3] = savm[s1][3]: probability, being at state
        !          3169:             s1 at precedent wave, to be dead a month before current
        !          3170:             wave is equal to probability, being at state s1 at
        !          3171:             precedent wave, to be dead at mont of the current
        !          3172:             wave. Then the observed probability (that this person died)
        !          3173:             is null according to current estimated parameter. In fact,
        !          3174:             it should be very low but not zero otherwise the log go to
        !          3175:             infinity.
        !          3176:          */
1.183     brouard  3177: /* #ifdef INFINITYORIGINAL */
                   3178: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3179: /* #else */
                   3180: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3181: /*         lli=log(mytinydouble); */
                   3182: /*       else */
                   3183: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3184: /* #endif */
1.226     brouard  3185:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3186:          
1.226     brouard  3187:        } else if  ( s2==-1 ) { /* alive */
                   3188:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3189:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3190:          /*survp += out[s1][j]; */
                   3191:          lli= log(survp);
                   3192:        }
                   3193:        else if  (s2==-4) { 
                   3194:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3195:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3196:          lli= log(survp); 
                   3197:        } 
                   3198:        else if  (s2==-5) { 
                   3199:          for (j=1,survp=0. ; j<=2; j++)  
                   3200:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3201:          lli= log(survp); 
                   3202:        } 
                   3203:        else{
                   3204:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3205:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3206:        } 
                   3207:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3208:        /*if(lli ==000.0)*/
                   3209:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3210:        ipmx +=1;
                   3211:        sw += weight[i];
                   3212:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3213:        /* if (lli < log(mytinydouble)){ */
                   3214:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3215:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3216:        /* } */
                   3217:       } /* end of wave */
                   3218:     } /* end of individual */
                   3219:   }  else if(mle==2){
                   3220:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3221:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3222:       for(mi=1; mi<= wav[i]-1; mi++){
                   3223:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3224:          for (j=1;j<=nlstate+ndeath;j++){
                   3225:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3226:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3227:          }
                   3228:        for(d=0; d<=dh[mi][i]; d++){
                   3229:          newm=savm;
                   3230:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3231:          cov[2]=agexact;
                   3232:          if(nagesqr==1)
                   3233:            cov[3]= agexact*agexact;
                   3234:          for (kk=1; kk<=cptcovage;kk++) {
                   3235:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3236:          }
                   3237:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3238:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3239:          savm=oldm;
                   3240:          oldm=newm;
                   3241:        } /* end mult */
                   3242:       
                   3243:        s1=s[mw[mi][i]][i];
                   3244:        s2=s[mw[mi+1][i]][i];
                   3245:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3246:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3247:        ipmx +=1;
                   3248:        sw += weight[i];
                   3249:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3250:       } /* end of wave */
                   3251:     } /* end of individual */
                   3252:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3253:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3254:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3255:       for(mi=1; mi<= wav[i]-1; mi++){
                   3256:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3257:          for (j=1;j<=nlstate+ndeath;j++){
                   3258:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3259:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3260:          }
                   3261:        for(d=0; d<dh[mi][i]; d++){
                   3262:          newm=savm;
                   3263:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3264:          cov[2]=agexact;
                   3265:          if(nagesqr==1)
                   3266:            cov[3]= agexact*agexact;
                   3267:          for (kk=1; kk<=cptcovage;kk++) {
                   3268:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3269:          }
                   3270:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3271:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3272:          savm=oldm;
                   3273:          oldm=newm;
                   3274:        } /* end mult */
                   3275:       
                   3276:        s1=s[mw[mi][i]][i];
                   3277:        s2=s[mw[mi+1][i]][i];
                   3278:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3279:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3280:        ipmx +=1;
                   3281:        sw += weight[i];
                   3282:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3283:       } /* end of wave */
                   3284:     } /* end of individual */
                   3285:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3286:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3287:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3288:       for(mi=1; mi<= wav[i]-1; mi++){
                   3289:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3290:          for (j=1;j<=nlstate+ndeath;j++){
                   3291:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3292:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3293:          }
                   3294:        for(d=0; d<dh[mi][i]; d++){
                   3295:          newm=savm;
                   3296:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3297:          cov[2]=agexact;
                   3298:          if(nagesqr==1)
                   3299:            cov[3]= agexact*agexact;
                   3300:          for (kk=1; kk<=cptcovage;kk++) {
                   3301:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3302:          }
1.126     brouard  3303:        
1.226     brouard  3304:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3305:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3306:          savm=oldm;
                   3307:          oldm=newm;
                   3308:        } /* end mult */
                   3309:       
                   3310:        s1=s[mw[mi][i]][i];
                   3311:        s2=s[mw[mi+1][i]][i];
                   3312:        if( s2 > nlstate){ 
                   3313:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3314:        } else if  ( s2==-1 ) { /* alive */
                   3315:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3316:            survp += out[s1][j];
                   3317:          lli= log(survp);
                   3318:        }else{
                   3319:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3320:        }
                   3321:        ipmx +=1;
                   3322:        sw += weight[i];
                   3323:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3324: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3325:       } /* end of wave */
                   3326:     } /* end of individual */
                   3327:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3328:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3329:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3330:       for(mi=1; mi<= wav[i]-1; mi++){
                   3331:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3332:          for (j=1;j<=nlstate+ndeath;j++){
                   3333:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3334:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3335:          }
                   3336:        for(d=0; d<dh[mi][i]; d++){
                   3337:          newm=savm;
                   3338:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3339:          cov[2]=agexact;
                   3340:          if(nagesqr==1)
                   3341:            cov[3]= agexact*agexact;
                   3342:          for (kk=1; kk<=cptcovage;kk++) {
                   3343:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3344:          }
1.126     brouard  3345:        
1.226     brouard  3346:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3347:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3348:          savm=oldm;
                   3349:          oldm=newm;
                   3350:        } /* end mult */
                   3351:       
                   3352:        s1=s[mw[mi][i]][i];
                   3353:        s2=s[mw[mi+1][i]][i];
                   3354:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3355:        ipmx +=1;
                   3356:        sw += weight[i];
                   3357:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3358:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3359:       } /* end of wave */
                   3360:     } /* end of individual */
                   3361:   } /* End of if */
                   3362:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3363:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3364:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3365:   return -l;
1.126     brouard  3366: }
                   3367: 
                   3368: /*************** log-likelihood *************/
                   3369: double funcone( double *x)
                   3370: {
1.228     brouard  3371:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3372:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3373:   int ioffset=0;
1.131     brouard  3374:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3375:   double **out;
                   3376:   double lli; /* Individual log likelihood */
                   3377:   double llt;
                   3378:   int s1, s2;
1.228     brouard  3379:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3380: 
1.126     brouard  3381:   double bbh, survp;
1.187     brouard  3382:   double agexact;
1.214     brouard  3383:   double agebegin, ageend;
1.126     brouard  3384:   /*extern weight */
                   3385:   /* We are differentiating ll according to initial status */
                   3386:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3387:   /*for(i=1;i<imx;i++) 
                   3388:     printf(" %d\n",s[4][i]);
                   3389:   */
                   3390:   cov[1]=1.;
                   3391: 
                   3392:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3393:   ioffset=0;
                   3394:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.225     brouard  3395:     ioffset=2+nagesqr+cptcovage;
1.232     brouard  3396:     /* Fixed */
1.224     brouard  3397:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3398:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3399:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3400:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3401: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3402: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3403: /*    cov[2+6]=covar[2][i]; V2  */
                   3404: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3405: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3406: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3407: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3408: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3409: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3410:     }
1.232     brouard  3411:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3412:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3413:     /* } */
1.231     brouard  3414:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3415:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3416:     /* } */
1.225     brouard  3417:     
1.233     brouard  3418: 
                   3419:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3420:     /* Wave varying (but not age varying) */
                   3421:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.233     brouard  3422:                                cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i];
1.232     brouard  3423:                        }
                   3424:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.231     brouard  3425:                                /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3426:                                /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
1.232     brouard  3427:                                /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3428:                                /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
1.231     brouard  3429:                                /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3430:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
                   3431:                        /*      iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3432:                        /*      /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3433:                        /*      cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
                   3434:       /* } */
1.126     brouard  3435:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.231     brouard  3436:                                for (j=1;j<=nlstate+ndeath;j++){
                   3437:                                        oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3438:                                        savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3439:                                }
1.214     brouard  3440:       
                   3441:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3442:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3443:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.231     brouard  3444:                                /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3445:                                        and mw[mi+1][i]. dh depends on stepm.*/
                   3446:                                newm=savm;
                   3447:                                agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3448:                                cov[2]=agexact;
                   3449:                                if(nagesqr==1)
                   3450:                                        cov[3]= agexact*agexact;
                   3451:                                for (kk=1; kk<=cptcovage;kk++) {
                   3452:                                        cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3453:                                }
                   3454:                                /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3455:                                /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3456:                                out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3457:                                                                                 1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3458:                                /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3459:                                /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3460:                                savm=oldm;
                   3461:                                oldm=newm;
1.126     brouard  3462:       } /* end mult */
                   3463:       
                   3464:       s1=s[mw[mi][i]][i];
                   3465:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3466:       /* if(s2==-1){ */
                   3467:       /*       printf(" s1=%d, s2=%d i=%d \n", s1, s2, i); */
                   3468:       /*       /\* exit(1); *\/ */
                   3469:       /* } */
1.126     brouard  3470:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3471:       /* bias is positive if real duration
                   3472:        * is higher than the multiple of stepm and negative otherwise.
                   3473:        */
                   3474:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.232     brouard  3475:                                lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3476:       } else if  ( s2==-1 ) { /* alive */
1.232     brouard  3477:                                for (j=1,survp=0. ; j<=nlstate; j++) 
                   3478:                                        survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3479:                                lli= log(survp);
1.126     brouard  3480:       }else if (mle==1){
1.232     brouard  3481:                                lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3482:       } else if(mle==2){
1.232     brouard  3483:                                lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3484:       } else if(mle==3){  /* exponential inter-extrapolation */
1.232     brouard  3485:                                lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3486:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.232     brouard  3487:                                lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3488:       } else{  /* mle=0 back to 1 */
1.232     brouard  3489:                                lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3490:                                /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3491:       } /* End of if */
                   3492:       ipmx +=1;
                   3493:       sw += weight[i];
                   3494:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3495:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3496:       if(globpr){
1.232     brouard  3497:                                fprintf(ficresilk,"%9ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3498:  %11.6f %11.6f %11.6f ", \
1.232     brouard  3499:                                                                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
                   3500:                                                                2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
                   3501:                                for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3502:                                        llt +=ll[k]*gipmx/gsw;
                   3503:                                        fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3504:                                }
                   3505:                                fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3506:       }
1.232     brouard  3507:        } /* end of wave */
                   3508: } /* end of individual */
                   3509: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3510: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3511: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3512: if(globpr==0){ /* First time we count the contributions and weights */
                   3513:        gipmx=ipmx;
                   3514:        gsw=sw;
                   3515: }
                   3516: return -l;
1.126     brouard  3517: }
                   3518: 
                   3519: 
                   3520: /*************** function likelione ***********/
                   3521: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3522: {
                   3523:   /* This routine should help understanding what is done with 
                   3524:      the selection of individuals/waves and
                   3525:      to check the exact contribution to the likelihood.
                   3526:      Plotting could be done.
                   3527:    */
                   3528:   int k;
                   3529: 
                   3530:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3531:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3532:     strcat(fileresilk,fileresu);
1.126     brouard  3533:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3534:       printf("Problem with resultfile: %s\n", fileresilk);
                   3535:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3536:     }
1.214     brouard  3537:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3538:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3539:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3540:     for(k=1; k<=nlstate; k++) 
                   3541:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3542:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3543:   }
                   3544: 
                   3545:   *fretone=(*funcone)(p);
                   3546:   if(*globpri !=0){
                   3547:     fclose(ficresilk);
1.205     brouard  3548:     if (mle ==0)
                   3549:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3550:     else if(mle >=1)
                   3551:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3552:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3553:     
1.208     brouard  3554:       
                   3555:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3556:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3557: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3558:     }
1.207     brouard  3559:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3560: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3561:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3562: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3563:     fflush(fichtm);
1.205     brouard  3564:   }
1.126     brouard  3565:   return;
                   3566: }
                   3567: 
                   3568: 
                   3569: /*********** Maximum Likelihood Estimation ***************/
                   3570: 
                   3571: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3572: {
1.165     brouard  3573:   int i,j, iter=0;
1.126     brouard  3574:   double **xi;
                   3575:   double fret;
                   3576:   double fretone; /* Only one call to likelihood */
                   3577:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3578: 
                   3579: #ifdef NLOPT
                   3580:   int creturn;
                   3581:   nlopt_opt opt;
                   3582:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3583:   double *lb;
                   3584:   double minf; /* the minimum objective value, upon return */
                   3585:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3586:   myfunc_data dinst, *d = &dinst;
                   3587: #endif
                   3588: 
                   3589: 
1.126     brouard  3590:   xi=matrix(1,npar,1,npar);
                   3591:   for (i=1;i<=npar;i++)
                   3592:     for (j=1;j<=npar;j++)
                   3593:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3594:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3595:   strcpy(filerespow,"POW_"); 
1.126     brouard  3596:   strcat(filerespow,fileres);
                   3597:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3598:     printf("Problem with resultfile: %s\n", filerespow);
                   3599:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3600:   }
                   3601:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3602:   for (i=1;i<=nlstate;i++)
                   3603:     for(j=1;j<=nlstate+ndeath;j++)
                   3604:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3605:   fprintf(ficrespow,"\n");
1.162     brouard  3606: #ifdef POWELL
1.126     brouard  3607:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3608: #endif
1.126     brouard  3609: 
1.162     brouard  3610: #ifdef NLOPT
                   3611: #ifdef NEWUOA
                   3612:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3613: #else
                   3614:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3615: #endif
                   3616:   lb=vector(0,npar-1);
                   3617:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3618:   nlopt_set_lower_bounds(opt, lb);
                   3619:   nlopt_set_initial_step1(opt, 0.1);
                   3620:   
                   3621:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3622:   d->function = func;
                   3623:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3624:   nlopt_set_min_objective(opt, myfunc, d);
                   3625:   nlopt_set_xtol_rel(opt, ftol);
                   3626:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3627:     printf("nlopt failed! %d\n",creturn); 
                   3628:   }
                   3629:   else {
                   3630:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3631:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3632:     iter=1; /* not equal */
                   3633:   }
                   3634:   nlopt_destroy(opt);
                   3635: #endif
1.126     brouard  3636:   free_matrix(xi,1,npar,1,npar);
                   3637:   fclose(ficrespow);
1.203     brouard  3638:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3639:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3640:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3641: 
                   3642: }
                   3643: 
                   3644: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3645: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3646: {
                   3647:   double  **a,**y,*x,pd;
1.203     brouard  3648:   /* double **hess; */
1.164     brouard  3649:   int i, j;
1.126     brouard  3650:   int *indx;
                   3651: 
                   3652:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3653:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3654:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3655:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3656:   double gompertz(double p[]);
1.203     brouard  3657:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3658: 
                   3659:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3660:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3661:   for (i=1;i<=npar;i++){
1.203     brouard  3662:     printf("%d-",i);fflush(stdout);
                   3663:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3664:    
                   3665:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3666:     
                   3667:     /*  printf(" %f ",p[i]);
                   3668:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3669:   }
                   3670:   
                   3671:   for (i=1;i<=npar;i++) {
                   3672:     for (j=1;j<=npar;j++)  {
                   3673:       if (j>i) { 
1.203     brouard  3674:        printf(".%d-%d",i,j);fflush(stdout);
                   3675:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3676:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3677:        
                   3678:        hess[j][i]=hess[i][j];    
                   3679:        /*printf(" %lf ",hess[i][j]);*/
                   3680:       }
                   3681:     }
                   3682:   }
                   3683:   printf("\n");
                   3684:   fprintf(ficlog,"\n");
                   3685: 
                   3686:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3687:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3688:   
                   3689:   a=matrix(1,npar,1,npar);
                   3690:   y=matrix(1,npar,1,npar);
                   3691:   x=vector(1,npar);
                   3692:   indx=ivector(1,npar);
                   3693:   for (i=1;i<=npar;i++)
                   3694:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3695:   ludcmp(a,npar,indx,&pd);
                   3696: 
                   3697:   for (j=1;j<=npar;j++) {
                   3698:     for (i=1;i<=npar;i++) x[i]=0;
                   3699:     x[j]=1;
                   3700:     lubksb(a,npar,indx,x);
                   3701:     for (i=1;i<=npar;i++){ 
                   3702:       matcov[i][j]=x[i];
                   3703:     }
                   3704:   }
                   3705: 
                   3706:   printf("\n#Hessian matrix#\n");
                   3707:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   3708:   for (i=1;i<=npar;i++) { 
                   3709:     for (j=1;j<=npar;j++) { 
1.203     brouard  3710:       printf("%.6e ",hess[i][j]);
                   3711:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  3712:     }
                   3713:     printf("\n");
                   3714:     fprintf(ficlog,"\n");
                   3715:   }
                   3716: 
1.203     brouard  3717:   /* printf("\n#Covariance matrix#\n"); */
                   3718:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   3719:   /* for (i=1;i<=npar;i++) {  */
                   3720:   /*   for (j=1;j<=npar;j++) {  */
                   3721:   /*     printf("%.6e ",matcov[i][j]); */
                   3722:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   3723:   /*   } */
                   3724:   /*   printf("\n"); */
                   3725:   /*   fprintf(ficlog,"\n"); */
                   3726:   /* } */
                   3727: 
1.126     brouard  3728:   /* Recompute Inverse */
1.203     brouard  3729:   /* for (i=1;i<=npar;i++) */
                   3730:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   3731:   /* ludcmp(a,npar,indx,&pd); */
                   3732: 
                   3733:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   3734: 
                   3735:   /* for (j=1;j<=npar;j++) { */
                   3736:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   3737:   /*   x[j]=1; */
                   3738:   /*   lubksb(a,npar,indx,x); */
                   3739:   /*   for (i=1;i<=npar;i++){  */
                   3740:   /*     y[i][j]=x[i]; */
                   3741:   /*     printf("%.3e ",y[i][j]); */
                   3742:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   3743:   /*   } */
                   3744:   /*   printf("\n"); */
                   3745:   /*   fprintf(ficlog,"\n"); */
                   3746:   /* } */
                   3747: 
                   3748:   /* Verifying the inverse matrix */
                   3749: #ifdef DEBUGHESS
                   3750:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  3751: 
1.203     brouard  3752:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   3753:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  3754: 
                   3755:   for (j=1;j<=npar;j++) {
                   3756:     for (i=1;i<=npar;i++){ 
1.203     brouard  3757:       printf("%.2f ",y[i][j]);
                   3758:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  3759:     }
                   3760:     printf("\n");
                   3761:     fprintf(ficlog,"\n");
                   3762:   }
1.203     brouard  3763: #endif
1.126     brouard  3764: 
                   3765:   free_matrix(a,1,npar,1,npar);
                   3766:   free_matrix(y,1,npar,1,npar);
                   3767:   free_vector(x,1,npar);
                   3768:   free_ivector(indx,1,npar);
1.203     brouard  3769:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  3770: 
                   3771: 
                   3772: }
                   3773: 
                   3774: /*************** hessian matrix ****************/
                   3775: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  3776: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  3777:   int i;
                   3778:   int l=1, lmax=20;
1.203     brouard  3779:   double k1,k2, res, fx;
1.132     brouard  3780:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  3781:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   3782:   int k=0,kmax=10;
                   3783:   double l1;
                   3784: 
                   3785:   fx=func(x);
                   3786:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  3787:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  3788:     l1=pow(10,l);
                   3789:     delts=delt;
                   3790:     for(k=1 ; k <kmax; k=k+1){
                   3791:       delt = delta*(l1*k);
                   3792:       p2[theta]=x[theta] +delt;
1.145     brouard  3793:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  3794:       p2[theta]=x[theta]-delt;
                   3795:       k2=func(p2)-fx;
                   3796:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  3797:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  3798:       
1.203     brouard  3799: #ifdef DEBUGHESSII
1.126     brouard  3800:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3801:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3802: #endif
                   3803:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   3804:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   3805:        k=kmax;
                   3806:       }
                   3807:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  3808:        k=kmax; l=lmax*10;
1.126     brouard  3809:       }
                   3810:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   3811:        delts=delt;
                   3812:       }
1.203     brouard  3813:     } /* End loop k */
1.126     brouard  3814:   }
                   3815:   delti[theta]=delts;
                   3816:   return res; 
                   3817:   
                   3818: }
                   3819: 
1.203     brouard  3820: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  3821: {
                   3822:   int i;
1.164     brouard  3823:   int l=1, lmax=20;
1.126     brouard  3824:   double k1,k2,k3,k4,res,fx;
1.132     brouard  3825:   double p2[MAXPARM+1];
1.203     brouard  3826:   int k, kmax=1;
                   3827:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  3828: 
                   3829:   int firstime=0;
1.203     brouard  3830:   
1.126     brouard  3831:   fx=func(x);
1.203     brouard  3832:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  3833:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  3834:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   3835:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  3836:     k1=func(p2)-fx;
                   3837:   
1.203     brouard  3838:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   3839:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  3840:     k2=func(p2)-fx;
                   3841:   
1.203     brouard  3842:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   3843:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  3844:     k3=func(p2)-fx;
                   3845:   
1.203     brouard  3846:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   3847:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  3848:     k4=func(p2)-fx;
1.203     brouard  3849:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   3850:     if(k1*k2*k3*k4 <0.){
1.208     brouard  3851:       firstime=1;
1.203     brouard  3852:       kmax=kmax+10;
1.208     brouard  3853:     }
                   3854:     if(kmax >=10 || firstime ==1){
1.218     brouard  3855:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you may increase ftol=%.2e\n",thetai,thetaj, ftol);
                   3856:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you may increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  3857:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   3858:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   3859:     }
                   3860: #ifdef DEBUGHESSIJ
                   3861:     v1=hess[thetai][thetai];
                   3862:     v2=hess[thetaj][thetaj];
                   3863:     cv12=res;
                   3864:     /* Computing eigen value of Hessian matrix */
                   3865:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   3866:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   3867:     if ((lc2 <0) || (lc1 <0) ){
                   3868:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   3869:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   3870:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   3871:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   3872:     }
1.126     brouard  3873: #endif
                   3874:   }
                   3875:   return res;
                   3876: }
                   3877: 
1.203     brouard  3878:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   3879: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   3880: /* { */
                   3881: /*   int i; */
                   3882: /*   int l=1, lmax=20; */
                   3883: /*   double k1,k2,k3,k4,res,fx; */
                   3884: /*   double p2[MAXPARM+1]; */
                   3885: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   3886: /*   int k=0,kmax=10; */
                   3887: /*   double l1; */
                   3888:   
                   3889: /*   fx=func(x); */
                   3890: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   3891: /*     l1=pow(10,l); */
                   3892: /*     delts=delt; */
                   3893: /*     for(k=1 ; k <kmax; k=k+1){ */
                   3894: /*       delt = delti*(l1*k); */
                   3895: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   3896: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   3897: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   3898: /*       k1=func(p2)-fx; */
                   3899:       
                   3900: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   3901: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   3902: /*       k2=func(p2)-fx; */
                   3903:       
                   3904: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   3905: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   3906: /*       k3=func(p2)-fx; */
                   3907:       
                   3908: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   3909: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   3910: /*       k4=func(p2)-fx; */
                   3911: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   3912: /* #ifdef DEBUGHESSIJ */
                   3913: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   3914: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   3915: /* #endif */
                   3916: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   3917: /*     k=kmax; */
                   3918: /*       } */
                   3919: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   3920: /*     k=kmax; l=lmax*10; */
                   3921: /*       } */
                   3922: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   3923: /*     delts=delt; */
                   3924: /*       } */
                   3925: /*     } /\* End loop k *\/ */
                   3926: /*   } */
                   3927: /*   delti[theta]=delts; */
                   3928: /*   return res;  */
                   3929: /* } */
                   3930: 
                   3931: 
1.126     brouard  3932: /************** Inverse of matrix **************/
                   3933: void ludcmp(double **a, int n, int *indx, double *d) 
                   3934: { 
                   3935:   int i,imax,j,k; 
                   3936:   double big,dum,sum,temp; 
                   3937:   double *vv; 
                   3938:  
                   3939:   vv=vector(1,n); 
                   3940:   *d=1.0; 
                   3941:   for (i=1;i<=n;i++) { 
                   3942:     big=0.0; 
                   3943:     for (j=1;j<=n;j++) 
                   3944:       if ((temp=fabs(a[i][j])) > big) big=temp; 
                   3945:     if (big == 0.0) nrerror("Singular matrix in routine ludcmp"); 
                   3946:     vv[i]=1.0/big; 
                   3947:   } 
                   3948:   for (j=1;j<=n;j++) { 
                   3949:     for (i=1;i<j;i++) { 
                   3950:       sum=a[i][j]; 
                   3951:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   3952:       a[i][j]=sum; 
                   3953:     } 
                   3954:     big=0.0; 
                   3955:     for (i=j;i<=n;i++) { 
                   3956:       sum=a[i][j]; 
                   3957:       for (k=1;k<j;k++) 
                   3958:        sum -= a[i][k]*a[k][j]; 
                   3959:       a[i][j]=sum; 
                   3960:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   3961:        big=dum; 
                   3962:        imax=i; 
                   3963:       } 
                   3964:     } 
                   3965:     if (j != imax) { 
                   3966:       for (k=1;k<=n;k++) { 
                   3967:        dum=a[imax][k]; 
                   3968:        a[imax][k]=a[j][k]; 
                   3969:        a[j][k]=dum; 
                   3970:       } 
                   3971:       *d = -(*d); 
                   3972:       vv[imax]=vv[j]; 
                   3973:     } 
                   3974:     indx[j]=imax; 
                   3975:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   3976:     if (j != n) { 
                   3977:       dum=1.0/(a[j][j]); 
                   3978:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   3979:     } 
                   3980:   } 
                   3981:   free_vector(vv,1,n);  /* Doesn't work */
                   3982: ;
                   3983: } 
                   3984: 
                   3985: void lubksb(double **a, int n, int *indx, double b[]) 
                   3986: { 
                   3987:   int i,ii=0,ip,j; 
                   3988:   double sum; 
                   3989:  
                   3990:   for (i=1;i<=n;i++) { 
                   3991:     ip=indx[i]; 
                   3992:     sum=b[ip]; 
                   3993:     b[ip]=b[i]; 
                   3994:     if (ii) 
                   3995:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   3996:     else if (sum) ii=i; 
                   3997:     b[i]=sum; 
                   3998:   } 
                   3999:   for (i=n;i>=1;i--) { 
                   4000:     sum=b[i]; 
                   4001:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4002:     b[i]=sum/a[i][i]; 
                   4003:   } 
                   4004: } 
                   4005: 
                   4006: void pstamp(FILE *fichier)
                   4007: {
1.196     brouard  4008:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4009: }
                   4010: 
                   4011: /************ Frequencies ********************/
1.226     brouard  4012: void  freqsummary(char fileres[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
                   4013:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4014:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
                   4015: {  /* Some frequencies */
                   4016:   
1.227     brouard  4017:   int i, m, jk, j1, bool, z1,j, k, iv;
1.226     brouard  4018:   int iind=0, iage=0;
                   4019:   int mi; /* Effective wave */
                   4020:   int first;
                   4021:   double ***freq; /* Frequencies */
                   4022:   double *meanq;
                   4023:   double **meanqt;
                   4024:   double *pp, **prop, *posprop, *pospropt;
                   4025:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4026:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4027:   double agebegin, ageend;
                   4028:     
                   4029:   pp=vector(1,nlstate);
                   4030:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+3+AGEMARGE); 
                   4031:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4032:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4033:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4034:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4035:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4036:   strcpy(fileresp,"P_");
                   4037:   strcat(fileresp,fileresu);
                   4038:   /*strcat(fileresphtm,fileresu);*/
                   4039:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4040:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4041:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4042:     exit(0);
                   4043:   }
1.214     brouard  4044: 
1.226     brouard  4045:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4046:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4047:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4048:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4049:     fflush(ficlog);
                   4050:     exit(70); 
                   4051:   }
                   4052:   else{
                   4053:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.214     brouard  4054: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   4055: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4056:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4057:   }
                   4058:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition</h4>\n",fileresphtm, fileresphtm);
1.214     brouard  4059:     
1.226     brouard  4060:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4061:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4062:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4063:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4064:     fflush(ficlog);
                   4065:     exit(70); 
                   4066:   }
                   4067:   else{
                   4068:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.214     brouard  4069: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   4070: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4071:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4072:   }
                   4073:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions by age at begin of transition </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
1.214     brouard  4074: 
1.226     brouard  4075:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+3+AGEMARGE);
                   4076:   j1=0;
1.126     brouard  4077:   
1.227     brouard  4078:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4079:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4080:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.220     brouard  4081: 
1.226     brouard  4082:   first=1;
1.220     brouard  4083: 
1.226     brouard  4084:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4085:      reference=low_education V1=0,V2=0
                   4086:      med_educ                V1=1 V2=0, 
                   4087:      high_educ               V1=0 V2=1
                   4088:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4089:   */
1.126     brouard  4090: 
1.227     brouard  4091:   for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on covariates combination in order of model, excluding quantitatives V4=0, V3=0 for example, fixed or varying covariates */
1.226     brouard  4092:     posproptt=0.;
                   4093:     /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4094:       scanf("%d", i);*/
                   4095:     for (i=-5; i<=nlstate+ndeath; i++)  
                   4096:       for (jk=-5; jk<=nlstate+ndeath; jk++)  
1.231     brouard  4097:                                for(m=iagemin; m <= iagemax+3; m++)
                   4098:                                        freq[i][jk][m]=0;
                   4099:                
1.226     brouard  4100:     for (i=1; i<=nlstate; i++)  {
                   4101:       for(m=iagemin; m <= iagemax+3; m++)
1.231     brouard  4102:                                prop[i][m]=0;
1.226     brouard  4103:       posprop[i]=0;
                   4104:       pospropt[i]=0;
                   4105:     }
1.227     brouard  4106:     /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4107:     /*   meanq[z1]+=0.; */
                   4108:     /*   for(m=1;m<=lastpass;m++){ */
                   4109:     /*         meanqt[m][z1]=0.; */
                   4110:     /*   } */
                   4111:     /* } */
1.231     brouard  4112:                
1.226     brouard  4113:     dateintsum=0;
                   4114:     k2cpt=0;
1.227     brouard  4115:     /* For that combination of covariate j1, we count and print the frequencies in one pass */
1.226     brouard  4116:     for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4117:       bool=1;
1.227     brouard  4118:       if(anyvaryingduminmodel==0){ /* If All fixed covariates */
1.234   ! brouard  4119:        if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
1.227     brouard  4120:          /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4121:          /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4122:          /* } */
1.234   ! brouard  4123:          for (z1=1; z1<=cptcoveff; z1++) {  
        !          4124:            /* if(Tvaraff[z1] ==-20){ */
        !          4125:            /*   /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
        !          4126:            /* }else  if(Tvaraff[z1] ==-10){ */
        !          4127:            /*   /\* sumnew+=coqvar[z1][iind]; *\/ */
        !          4128:            /* }else  */
        !          4129:            if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){
        !          4130:              /* Tests if this individual iind responded to j1 (V4=1 V3=0) */
        !          4131:              bool=0;
        !          4132:              /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
        !          4133:                 bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
        !          4134:                 j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
        !          4135:              /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
        !          4136:            } /* Onlyf fixed */
        !          4137:          } /* end z1 */
        !          4138:        } /* cptcovn > 0 */
1.227     brouard  4139:       } /* end any */
                   4140:       if (bool==1){ /* We selected an individual iind satisfying combination j1 or all fixed */
1.234   ! brouard  4141:        /* for(m=firstpass; m<=lastpass; m++){ */
        !          4142:        for(mi=1; mi<wav[iind];mi++){ /* For that wave */
        !          4143:          m=mw[mi][iind];
        !          4144:          if(anyvaryingduminmodel==1){ /* Some are varying covariates */
        !          4145:            for (z1=1; z1<=cptcoveff; z1++) {
        !          4146:              if( Fixed[Tmodelind[z1]]==1){
        !          4147:                iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
        !          4148:                if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
        !          4149:                  bool=0;
        !          4150:              }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
        !          4151:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
        !          4152:                  bool=0;
        !          4153:                }
        !          4154:              }
        !          4155:            }
        !          4156:          }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
        !          4157:          /* bool =0 we keep that guy which corresponds to the combination of dummy values */
        !          4158:          if(bool==1){
        !          4159:            /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
        !          4160:               and mw[mi+1][iind]. dh depends on stepm. */
        !          4161:            agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
        !          4162:            ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
        !          4163:            if(m >=firstpass && m <=lastpass){
        !          4164:              k2=anint[m][iind]+(mint[m][iind]/12.);
        !          4165:              /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
        !          4166:              if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
        !          4167:              if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
        !          4168:              if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
        !          4169:                prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
        !          4170:              if (m<lastpass) {
        !          4171:                /* if(s[m][iind]==4 && s[m+1][iind]==4) */
        !          4172:                /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
        !          4173:                if(s[m][iind]==-1)
        !          4174:                  printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
        !          4175:                freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
        !          4176:                /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
        !          4177:                freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
        !          4178:              }
        !          4179:            } /* end if between passes */  
        !          4180:            if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99)) {
        !          4181:              dateintsum=dateintsum+k2;
        !          4182:              k2cpt++;
        !          4183:              /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
        !          4184:            }
        !          4185:          } /* end bool 2 */
        !          4186:        } /* end m */
1.226     brouard  4187:       } /* end bool */
                   4188:     } /* end iind = 1 to imx */
                   4189:     /* prop[s][age] is feeded for any initial and valid live state as well as
                   4190:        freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
1.231     brouard  4191:                
                   4192:                
1.226     brouard  4193:     /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
                   4194:     pstamp(ficresp);
1.227     brouard  4195:     /* if  (ncoveff>0) { */
                   4196:     if  (cptcoveff>0) {
1.226     brouard  4197:       fprintf(ficresp, "\n#********** Variable "); 
                   4198:       fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4199:       fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
1.227     brouard  4200:       for (z1=1; z1<=cptcoveff; z1++){
1.234   ! brouard  4201:        fprintf(ficresp, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
        !          4202:        fprintf(ficresphtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
        !          4203:        fprintf(ficresphtmfr, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.226     brouard  4204:       }
                   4205:       fprintf(ficresp, "**********\n#");
                   4206:       fprintf(ficresphtm, "**********</h3>\n");
                   4207:       fprintf(ficresphtmfr, "**********</h3>\n");
                   4208:       fprintf(ficlog, "\n#********** Variable "); 
1.227     brouard  4209:       for (z1=1; z1<=cptcoveff; z1++) fprintf(ficlog, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.226     brouard  4210:       fprintf(ficlog, "**********\n");
                   4211:     }
                   4212:     fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
                   4213:     for(i=1; i<=nlstate;i++) {
                   4214:       fprintf(ficresp, " Age Prev(%d) N(%d) N",i,i);
                   4215:       fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4216:     }
                   4217:     fprintf(ficresp, "\n");
                   4218:     fprintf(ficresphtm, "\n");
1.231     brouard  4219:                
1.226     brouard  4220:     /* Header of frequency table by age */
                   4221:     fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4222:     fprintf(ficresphtmfr,"<th>Age</th> ");
                   4223:     for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4224:       for(m=-1; m <=nlstate+ndeath; m++){
1.234   ! brouard  4225:        if(jk!=0 && m!=0)
        !          4226:          fprintf(ficresphtmfr,"<th>%d%d</th> ",jk,m);
1.226     brouard  4227:       }
                   4228:     }
                   4229:     fprintf(ficresphtmfr, "\n");
1.231     brouard  4230:                
1.226     brouard  4231:     /* For each age */
                   4232:     for(iage=iagemin; iage <= iagemax+3; iage++){
                   4233:       fprintf(ficresphtm,"<tr>");
                   4234:       if(iage==iagemax+1){
1.231     brouard  4235:                                fprintf(ficlog,"1");
                   4236:                                fprintf(ficresphtmfr,"<tr><th>0</th> ");
1.226     brouard  4237:       }else if(iage==iagemax+2){
1.231     brouard  4238:                                fprintf(ficlog,"0");
                   4239:                                fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
1.226     brouard  4240:       }else if(iage==iagemax+3){
1.231     brouard  4241:                                fprintf(ficlog,"Total");
                   4242:                                fprintf(ficresphtmfr,"<tr><th>Total</th> ");
1.226     brouard  4243:       }else{
1.231     brouard  4244:                                if(first==1){
                   4245:                                        first=0;
                   4246:                                        printf("See log file for details...\n");
                   4247:                                }
                   4248:                                fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4249:                                fprintf(ficlog,"Age %d", iage);
1.226     brouard  4250:       }
                   4251:       for(jk=1; jk <=nlstate ; jk++){
1.231     brouard  4252:                                for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
                   4253:                                        pp[jk] += freq[jk][m][iage]; 
1.226     brouard  4254:       }
                   4255:       for(jk=1; jk <=nlstate ; jk++){
1.231     brouard  4256:                                for(m=-1, pos=0; m <=0 ; m++)
                   4257:                                        pos += freq[jk][m][iage];
                   4258:                                if(pp[jk]>=1.e-10){
                   4259:                                        if(first==1){
                   4260:                                                printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4261:                                        }
                   4262:                                        fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4263:                                }else{
                   4264:                                        if(first==1)
                   4265:                                                printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
                   4266:                                        fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
                   4267:                                }
1.226     brouard  4268:       }
1.231     brouard  4269:                        
1.226     brouard  4270:       for(jk=1; jk <=nlstate ; jk++){ 
1.231     brouard  4271:                                /* posprop[jk]=0; */
                   4272:                                for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4273:                                        pp[jk] += freq[jk][m][iage];
1.226     brouard  4274:       }        /* pp[jk] is the total number of transitions starting from state jk and any ending status until this age */
1.231     brouard  4275:                        
1.226     brouard  4276:       for(jk=1,pos=0, pospropta=0.; jk <=nlstate ; jk++){
1.231     brouard  4277:                                pos += pp[jk]; /* pos is the total number of transitions until this age */
                   4278:                                posprop[jk] += prop[jk][iage]; /* prop is the number of transitions from a live state
                   4279:                                                                                                                                                                        from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4280:                                pospropta += prop[jk][iage]; /* prop is the number of transitions from a live state
                   4281:                                                                                                                                                                from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
1.226     brouard  4282:       }
                   4283:       for(jk=1; jk <=nlstate ; jk++){
1.231     brouard  4284:                                if(pos>=1.e-5){
                   4285:                                        if(first==1)
                   4286:                                                printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4287:                                        fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4288:                                }else{
                   4289:                                        if(first==1)
                   4290:                                                printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4291:                                        fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4292:                                }
                   4293:                                if( iage <= iagemax){
                   4294:                                        if(pos>=1.e-5){
                   4295:                                                fprintf(ficresp," %d %.5f %.0f %.0f",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4296:                                                fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4297:                                                /*probs[iage][jk][j1]= pp[jk]/pos;*/
                   4298:                                                /*printf("\niage=%d jk=%d j1=%d %.5f %.0f %.0f %f",iage,jk,j1,pp[jk]/pos, pp[jk],pos,probs[iage][jk][j1]);*/
                   4299:                                        }
                   4300:                                        else{
                   4301:                                                fprintf(ficresp," %d NaNq %.0f %.0f",iage,prop[jk][iage],pospropta);
                   4302:                                                fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[jk][iage],pospropta);
                   4303:                                        }
                   4304:                                }
                   4305:                                pospropt[jk] +=posprop[jk];
1.226     brouard  4306:       } /* end loop jk */
                   4307:       /* pospropt=0.; */
                   4308:       for(jk=-1; jk <=nlstate+ndeath; jk++){
1.231     brouard  4309:                                for(m=-1; m <=nlstate+ndeath; m++){
                   4310:                                        if(freq[jk][m][iage] !=0 ) { /* minimizing output */
                   4311:                                                if(first==1){
                   4312:                                                        printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4313:                                                }
                   4314:                                                fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4315:                                        }
                   4316:                                        if(jk!=0 && m!=0)
                   4317:                                                fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[jk][m][iage]);
                   4318:                                }
1.226     brouard  4319:       } /* end loop jk */
                   4320:       posproptt=0.; 
                   4321:       for(jk=1; jk <=nlstate; jk++){
1.231     brouard  4322:                                posproptt += pospropt[jk];
1.226     brouard  4323:       }
                   4324:       fprintf(ficresphtmfr,"</tr>\n ");
                   4325:       if(iage <= iagemax){
1.231     brouard  4326:                                fprintf(ficresp,"\n");
                   4327:                                fprintf(ficresphtm,"</tr>\n");
1.226     brouard  4328:       }
                   4329:       if(first==1)
1.231     brouard  4330:                                printf("Others in log...\n");
1.226     brouard  4331:       fprintf(ficlog,"\n");
                   4332:     } /* end loop age iage */
                   4333:     fprintf(ficresphtm,"<tr><th>Tot</th>");
                   4334:     for(jk=1; jk <=nlstate ; jk++){
                   4335:       if(posproptt < 1.e-5){
1.231     brouard  4336:                                fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[jk],posproptt);   
1.226     brouard  4337:       }else{
1.231     brouard  4338:                                fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[jk]/posproptt,pospropt[jk],posproptt);    
1.226     brouard  4339:       }
                   4340:     }
                   4341:     fprintf(ficresphtm,"</tr>\n");
                   4342:     fprintf(ficresphtm,"</table>\n");
                   4343:     fprintf(ficresphtmfr,"</table>\n");
                   4344:     if(posproptt < 1.e-5){
                   4345:       fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4346:       fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4347:       fprintf(ficres,"\n  This combination (%d) is not valid and no result will be produced\n\n",j1);
                   4348:       invalidvarcomb[j1]=1;
                   4349:     }else{
                   4350:       fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4351:       invalidvarcomb[j1]=0;
                   4352:     }
                   4353:     fprintf(ficresphtmfr,"</table>\n");
                   4354:   } /* end selected combination of covariate j1 */
                   4355:   dateintmean=dateintsum/k2cpt; 
1.231     brouard  4356:        
1.226     brouard  4357:   fclose(ficresp);
                   4358:   fclose(ficresphtm);
                   4359:   fclose(ficresphtmfr);
                   4360:   free_vector(meanq,1,nqfveff);
                   4361:   free_matrix(meanqt,1,lastpass,1,nqtveff);
                   4362:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+3+AGEMARGE);
                   4363:   free_vector(pospropt,1,nlstate);
                   4364:   free_vector(posprop,1,nlstate);
                   4365:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+3+AGEMARGE);
                   4366:   free_vector(pp,1,nlstate);
                   4367:   /* End of freqsummary */
                   4368: }
1.126     brouard  4369: 
                   4370: /************ Prevalence ********************/
1.227     brouard  4371: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4372: {  
                   4373:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4374:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4375:      We still use firstpass and lastpass as another selection.
                   4376:   */
1.126     brouard  4377:  
1.227     brouard  4378:   int i, m, jk, j1, bool, z1,j, iv;
                   4379:   int mi; /* Effective wave */
                   4380:   int iage;
                   4381:   double agebegin, ageend;
                   4382: 
                   4383:   double **prop;
                   4384:   double posprop; 
                   4385:   double  y2; /* in fractional years */
                   4386:   int iagemin, iagemax;
                   4387:   int first; /** to stop verbosity which is redirected to log file */
                   4388: 
                   4389:   iagemin= (int) agemin;
                   4390:   iagemax= (int) agemax;
                   4391:   /*pp=vector(1,nlstate);*/
                   4392:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+3+AGEMARGE); 
                   4393:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4394:   j1=0;
1.222     brouard  4395:   
1.227     brouard  4396:   /*j=cptcoveff;*/
                   4397:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4398:   
1.227     brouard  4399:   first=1;
                   4400:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4401:     for (i=1; i<=nlstate; i++)  
                   4402:       for(iage=iagemin-AGEMARGE; iage <= iagemax+3+AGEMARGE; iage++)
                   4403:        prop[i][iage]=0.0;
                   4404:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4405:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4406:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4407:     
                   4408:     for (i=1; i<=imx; i++) { /* Each individual */
                   4409:       bool=1;
                   4410:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4411:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4412:        m=mw[mi][i];
                   4413:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4414:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4415:        for (z1=1; z1<=cptcoveff; z1++){
                   4416:          if( Fixed[Tmodelind[z1]]==1){
                   4417:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4418:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4419:              bool=0;
                   4420:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4421:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4422:              bool=0;
                   4423:            }
                   4424:        }
                   4425:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4426:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4427:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4428:          if(m >=firstpass && m <=lastpass){
                   4429:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4430:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4431:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   4432:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
                   4433:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+3+AGEMARGE){
                   4434:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   4435:                exit(1);
                   4436:              }
                   4437:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   4438:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   4439:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   4440:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   4441:              } /* end valid statuses */ 
                   4442:            } /* end selection of dates */
                   4443:          } /* end selection of waves */
                   4444:        } /* end bool */
                   4445:       } /* end wave */
                   4446:     } /* end individual */
                   4447:     for(i=iagemin; i <= iagemax+3; i++){  
                   4448:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   4449:        posprop += prop[jk][i]; 
                   4450:       } 
                   4451:       
                   4452:       for(jk=1; jk <=nlstate ; jk++){      
                   4453:        if( i <=  iagemax){ 
                   4454:          if(posprop>=1.e-5){ 
                   4455:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   4456:          } else{
                   4457:            if(first==1){
                   4458:              first=0;
                   4459:              printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,j1,probs[i][jk][j1]);
                   4460:            }
                   4461:          }
                   4462:        } 
                   4463:       }/* end jk */ 
                   4464:     }/* end i */ 
1.222     brouard  4465:      /*} *//* end i1 */
1.227     brouard  4466:   } /* end j1 */
1.222     brouard  4467:   
1.227     brouard  4468:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   4469:   /*free_vector(pp,1,nlstate);*/
                   4470:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+3+AGEMARGE);
                   4471: }  /* End of prevalence */
1.126     brouard  4472: 
                   4473: /************* Waves Concatenation ***************/
                   4474: 
                   4475: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   4476: {
                   4477:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   4478:      Death is a valid wave (if date is known).
                   4479:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   4480:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4481:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  4482:   */
1.126     brouard  4483: 
1.224     brouard  4484:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  4485:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   4486:      double sum=0., jmean=0.;*/
1.224     brouard  4487:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  4488:   int j, k=0,jk, ju, jl;
                   4489:   double sum=0.;
                   4490:   first=0;
1.214     brouard  4491:   firstwo=0;
1.217     brouard  4492:   firsthree=0;
1.218     brouard  4493:   firstfour=0;
1.164     brouard  4494:   jmin=100000;
1.126     brouard  4495:   jmax=-1;
                   4496:   jmean=0.;
1.224     brouard  4497: 
                   4498: /* Treating live states */
1.214     brouard  4499:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  4500:     mi=0;  /* First valid wave */
1.227     brouard  4501:     mli=0; /* Last valid wave */
1.126     brouard  4502:     m=firstpass;
1.214     brouard  4503:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  4504:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   4505:        mli=m-1;/* mw[++mi][i]=m-1; */
                   4506:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   4507:        mw[++mi][i]=m;
                   4508:        mli=m;
1.224     brouard  4509:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   4510:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  4511:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  4512:       }
1.227     brouard  4513:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  4514: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  4515:        break;
1.224     brouard  4516: #else
1.227     brouard  4517:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   4518:          if(firsthree == 0){
                   4519:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4520:            firsthree=1;
                   4521:          }
                   4522:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4523:          mw[++mi][i]=m;
                   4524:          mli=m;
                   4525:        }
                   4526:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   4527:          nbwarn++;
                   4528:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   4529:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4530:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4531:          }
                   4532:          break;
                   4533:        }
                   4534:        break;
1.224     brouard  4535: #endif
1.227     brouard  4536:       }/* End m >= lastpass */
1.126     brouard  4537:     }/* end while */
1.224     brouard  4538: 
1.227     brouard  4539:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  4540:     /* After last pass */
1.224     brouard  4541: /* Treating death states */
1.214     brouard  4542:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  4543:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   4544:       /* } */
1.126     brouard  4545:       mi++;    /* Death is another wave */
                   4546:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  4547:       /* Only death is a correct wave */
1.126     brouard  4548:       mw[mi][i]=m;
1.224     brouard  4549:     }
                   4550: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.227     brouard  4551:     else if ((int) andc[i] != 9999) { /* Status is negative. A death occured after lastpass, we can't take it into account because of potential bias */
1.216     brouard  4552:       /* m++; */
                   4553:       /* mi++; */
                   4554:       /* s[m][i]=nlstate+1;  /\* We are setting the status to the last of non live state *\/ */
                   4555:       /* mw[mi][i]=m; */
1.218     brouard  4556:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  4557:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   4558:          nbwarn++;
                   4559:          if(firstfiv==0){
                   4560:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4561:            firstfiv=1;
                   4562:          }else{
                   4563:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4564:          }
                   4565:        }else{ /* Death occured afer last wave potential bias */
                   4566:          nberr++;
                   4567:          if(firstwo==0){
                   4568:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4569:            firstwo=1;
                   4570:          }
                   4571:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4572:        }
1.218     brouard  4573:       }else{ /* end date of interview is known */
1.227     brouard  4574:        /* death is known but not confirmed by death status at any wave */
                   4575:        if(firstfour==0){
                   4576:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4577:          firstfour=1;
                   4578:        }
                   4579:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  4580:       }
1.224     brouard  4581:     } /* end if date of death is known */
                   4582: #endif
                   4583:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   4584:     /* wav[i]=mw[mi][i]; */
1.126     brouard  4585:     if(mi==0){
                   4586:       nbwarn++;
                   4587:       if(first==0){
1.227     brouard  4588:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   4589:        first=1;
1.126     brouard  4590:       }
                   4591:       if(first==1){
1.227     brouard  4592:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  4593:       }
                   4594:     } /* end mi==0 */
                   4595:   } /* End individuals */
1.214     brouard  4596:   /* wav and mw are no more changed */
1.223     brouard  4597:        
1.214     brouard  4598:   
1.126     brouard  4599:   for(i=1; i<=imx; i++){
                   4600:     for(mi=1; mi<wav[i];mi++){
                   4601:       if (stepm <=0)
1.227     brouard  4602:        dh[mi][i]=1;
1.126     brouard  4603:       else{
1.227     brouard  4604:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death */
                   4605:          if (agedc[i] < 2*AGESUP) {
                   4606:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   4607:            if(j==0) j=1;  /* Survives at least one month after exam */
                   4608:            else if(j<0){
                   4609:              nberr++;
                   4610:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4611:              j=1; /* Temporary Dangerous patch */
                   4612:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   4613:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4614:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   4615:            }
                   4616:            k=k+1;
                   4617:            if (j >= jmax){
                   4618:              jmax=j;
                   4619:              ijmax=i;
                   4620:            }
                   4621:            if (j <= jmin){
                   4622:              jmin=j;
                   4623:              ijmin=i;
                   4624:            }
                   4625:            sum=sum+j;
                   4626:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   4627:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   4628:          }
                   4629:        }
                   4630:        else{
                   4631:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  4632: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  4633:                                        
1.227     brouard  4634:          k=k+1;
                   4635:          if (j >= jmax) {
                   4636:            jmax=j;
                   4637:            ijmax=i;
                   4638:          }
                   4639:          else if (j <= jmin){
                   4640:            jmin=j;
                   4641:            ijmin=i;
                   4642:          }
                   4643:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   4644:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   4645:          if(j<0){
                   4646:            nberr++;
                   4647:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4648:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4649:          }
                   4650:          sum=sum+j;
                   4651:        }
                   4652:        jk= j/stepm;
                   4653:        jl= j -jk*stepm;
                   4654:        ju= j -(jk+1)*stepm;
                   4655:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   4656:          if(jl==0){
                   4657:            dh[mi][i]=jk;
                   4658:            bh[mi][i]=0;
                   4659:          }else{ /* We want a negative bias in order to only have interpolation ie
                   4660:                  * to avoid the price of an extra matrix product in likelihood */
                   4661:            dh[mi][i]=jk+1;
                   4662:            bh[mi][i]=ju;
                   4663:          }
                   4664:        }else{
                   4665:          if(jl <= -ju){
                   4666:            dh[mi][i]=jk;
                   4667:            bh[mi][i]=jl;       /* bias is positive if real duration
                   4668:                                 * is higher than the multiple of stepm and negative otherwise.
                   4669:                                 */
                   4670:          }
                   4671:          else{
                   4672:            dh[mi][i]=jk+1;
                   4673:            bh[mi][i]=ju;
                   4674:          }
                   4675:          if(dh[mi][i]==0){
                   4676:            dh[mi][i]=1; /* At least one step */
                   4677:            bh[mi][i]=ju; /* At least one step */
                   4678:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   4679:          }
                   4680:        } /* end if mle */
1.126     brouard  4681:       }
                   4682:     } /* end wave */
                   4683:   }
                   4684:   jmean=sum/k;
                   4685:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  4686:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  4687: }
1.126     brouard  4688: 
                   4689: /*********** Tricode ****************************/
1.220     brouard  4690:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.126     brouard  4691: {
1.144     brouard  4692:   /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   4693:   /*     Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
1.169     brouard  4694:    * Boring subroutine which should only output nbcode[Tvar[j]][k]
1.224     brouard  4695:    * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   4696:    * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
1.144     brouard  4697:   */
1.130     brouard  4698: 
1.145     brouard  4699:   int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
1.136     brouard  4700:   int modmaxcovj=0; /* Modality max of covariates j */
1.145     brouard  4701:   int cptcode=0; /* Modality max of covariates j */
                   4702:   int modmincovj=0; /* Modality min of covariates j */
                   4703: 
                   4704: 
1.220     brouard  4705:   /* cptcoveff=0;  */
1.224     brouard  4706:        /* *cptcov=0; */
1.126     brouard  4707:  
1.144     brouard  4708:   for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  4709: 
1.224     brouard  4710:   /* Loop on covariates without age and products and no quantitative variable */
                   4711:   /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
1.227     brouard  4712:   for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   4713:     for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   4714:     if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   4715:       switch(Fixed[k]) {
                   4716:       case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
1.231     brouard  4717:                                for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   4718:                                        ij=(int)(covar[Tvar[k]][i]);
                   4719:                                        /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   4720:                                         * If product of Vn*Vm, still boolean *:
                   4721:                                         * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   4722:                                         * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   4723:                                        /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   4724:                                                 modality of the nth covariate of individual i. */
                   4725:                                        if (ij > modmaxcovj)
                   4726:                                                modmaxcovj=ij; 
                   4727:                                        else if (ij < modmincovj) 
                   4728:                                                modmincovj=ij; 
                   4729:                                        if ((ij < -1) && (ij > NCOVMAX)){
                   4730:                                                printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   4731:                                                exit(1);
                   4732:                                        }else
                   4733:                                                Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   4734:                                        /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   4735:                                        /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   4736:                                        /* getting the maximum value of the modality of the covariate
                   4737:                                                 (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   4738:                                                 female ies 1, then modmaxcovj=1.
                   4739:                                        */
                   4740:                                } /* end for loop on individuals i */
                   4741:                                printf(" Minimal and maximal values of %d th covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   4742:                                fprintf(ficlog," Minimal and maximal values of %d th covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   4743:                                cptcode=modmaxcovj;
                   4744:                                /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   4745:                                /*for (i=0; i<=cptcode; i++) {*/
                   4746:                                for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   4747:                                        printf("Frequencies of covariates %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   4748:                                        fprintf(ficlog, "Frequencies of covariates %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   4749:                                        if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   4750:                                                if( j != -1){
                   4751:                                                        ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   4752:                                                                                                                                 covariate for which somebody answered excluding 
                   4753:                                                                                                                                 undefined. Usually 2: 0 and 1. */
                   4754:                                                }
                   4755:                                                ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   4756:                                                                                                                                                covariate for which somebody answered including 
                   4757:                                                                                                                                                undefined. Usually 3: -1, 0 and 1. */
                   4758:                                        }       /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   4759:                                                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   4760:                                } /* Ndum[-1] number of undefined modalities */
                   4761:                        
                   4762:                                /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   4763:                                /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   4764:                                /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   4765:                                /* modmincovj=3; modmaxcovj = 7; */
                   4766:                                /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   4767:                                /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   4768:                          /*             defining two dummy variables: variables V1_1 and V1_2.*/
                   4769:              /* nbcode[Tvar[j]][ij]=k; */
                   4770:              /* nbcode[Tvar[j]][1]=0; */
                   4771:              /* nbcode[Tvar[j]][2]=1; */
                   4772:              /* nbcode[Tvar[j]][3]=2; */
                   4773:              /* To be continued (not working yet). */
                   4774:              ij=0; /* ij is similar to i but can jump over null modalities */
                   4775:                                for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   4776:          if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   4777:                  break;
                   4778:                }
                   4779:                                        ij++;
                   4780:                                        nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   4781:                                        cptcode = ij; /* New max modality for covar j */
                   4782:                                } /* end of loop on modality i=-1 to 1 or more */
                   4783:                                break;
1.227     brouard  4784:       case 1: /* Testing on varying covariate, could be simple and
                   4785:               * should look at waves or product of fixed *
                   4786:               * varying. No time to test -1, assuming 0 and 1 only */
1.231     brouard  4787:                                ij=0;
                   4788:                                for(i=0; i<=1;i++){
                   4789:                                        nbcode[Tvar[k]][++ij]=i;
                   4790:                                }
                   4791:                                break;
1.227     brouard  4792:       default:
1.231     brouard  4793:                                break;
1.227     brouard  4794:       } /* end switch */
                   4795:     } /* end dummy test */
1.225     brouard  4796:     
1.192     brouard  4797:     /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   4798:     /*         /\*recode from 0 *\/ */
                   4799:     /*                                      k is a modality. If we have model=V1+V1*sex  */
                   4800:     /*                                      then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   4801:     /*                                   But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   4802:     /*         } */
                   4803:     /*         /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   4804:     /*         if (ij > ncodemax[j]) { */
                   4805:     /*           printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   4806:     /*           fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   4807:     /*           break; */
                   4808:     /*         } */
                   4809:     /*   }  /\* end of loop on modality k *\/ */
1.137     brouard  4810:   } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   4811:   
1.225     brouard  4812:   for (k=-1; k< maxncov; k++) Ndum[k]=0; 
1.227     brouard  4813:   /* Look at fixed dummy (single or product) covariates to check empty modalities */
1.187     brouard  4814:   for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
1.225     brouard  4815:     /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
1.227     brouard  4816:     ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   4817:     Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   4818:     /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
1.225     brouard  4819:   } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   4820:   
                   4821:   ij=0;
1.227     brouard  4822:   /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   4823:   for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
1.225     brouard  4824:     /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
1.227     brouard  4825:     /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   4826:     if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   4827:       /* If product not in single variable we don't print results */
1.225     brouard  4828:       /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
1.230     brouard  4829:       ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   4830:       Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   4831:       Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
1.231     brouard  4832:       TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
1.227     brouard  4833:       if(Fixed[k]!=0)
                   4834:         anyvaryingduminmodel=1;
1.231     brouard  4835:                        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   4836:                        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   4837:                        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   4838:                        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   4839:                        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   4840:                        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
1.227     brouard  4841:     } 
1.225     brouard  4842:   } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   4843:   /* ij--; */
                   4844:   /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   4845:   *cptcov=ij; /*Number of total real effective covariates: effective
1.231     brouard  4846:                                                         * because they can be excluded from the model and real
                   4847:                                                         * if in the model but excluded because missing values, but how to get k from ij?*/
1.227     brouard  4848:   for(j=ij+1; j<= cptcovt; j++){
                   4849:     Tvaraff[j]=0;
                   4850:     Tmodelind[j]=0;
                   4851:   }
1.228     brouard  4852:   for(j=ntveff+1; j<= cptcovt; j++){
                   4853:     TmodelInvind[j]=0;
                   4854:   }
1.227     brouard  4855:   /* To be sorted */
                   4856:   ;
1.126     brouard  4857: }
                   4858: 
1.145     brouard  4859: 
1.126     brouard  4860: /*********** Health Expectancies ****************/
                   4861: 
1.127     brouard  4862: void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[] )
1.126     brouard  4863: 
                   4864: {
                   4865:   /* Health expectancies, no variances */
1.164     brouard  4866:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  4867:   int nhstepma, nstepma; /* Decreasing with age */
                   4868:   double age, agelim, hf;
                   4869:   double ***p3mat;
                   4870:   double eip;
                   4871: 
                   4872:   pstamp(ficreseij);
                   4873:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   4874:   fprintf(ficreseij,"# Age");
                   4875:   for(i=1; i<=nlstate;i++){
                   4876:     for(j=1; j<=nlstate;j++){
                   4877:       fprintf(ficreseij," e%1d%1d ",i,j);
                   4878:     }
                   4879:     fprintf(ficreseij," e%1d. ",i);
                   4880:   }
                   4881:   fprintf(ficreseij,"\n");
                   4882: 
                   4883:   
                   4884:   if(estepm < stepm){
                   4885:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   4886:   }
                   4887:   else  hstepm=estepm;   
                   4888:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   4889:    * This is mainly to measure the difference between two models: for example
                   4890:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   4891:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   4892:    * progression in between and thus overestimating or underestimating according
                   4893:    * to the curvature of the survival function. If, for the same date, we 
                   4894:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   4895:    * to compare the new estimate of Life expectancy with the same linear 
                   4896:    * hypothesis. A more precise result, taking into account a more precise
                   4897:    * curvature will be obtained if estepm is as small as stepm. */
                   4898: 
                   4899:   /* For example we decided to compute the life expectancy with the smallest unit */
                   4900:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   4901:      nhstepm is the number of hstepm from age to agelim 
                   4902:      nstepm is the number of stepm from age to agelin. 
                   4903:      Look at hpijx to understand the reason of that which relies in memory size
                   4904:      and note for a fixed period like estepm months */
                   4905:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   4906:      survival function given by stepm (the optimization length). Unfortunately it
                   4907:      means that if the survival funtion is printed only each two years of age and if
                   4908:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   4909:      results. So we changed our mind and took the option of the best precision.
                   4910:   */
                   4911:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   4912: 
                   4913:   agelim=AGESUP;
                   4914:   /* If stepm=6 months */
                   4915:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   4916:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   4917:     
                   4918: /* nhstepm age range expressed in number of stepm */
                   4919:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   4920:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   4921:   /* if (stepm >= YEARM) hstepm=1;*/
                   4922:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   4923:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   4924: 
                   4925:   for (age=bage; age<=fage; age ++){ 
                   4926:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   4927:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   4928:     /* if (stepm >= YEARM) hstepm=1;*/
                   4929:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   4930: 
                   4931:     /* If stepm=6 months */
                   4932:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   4933:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   4934:     
                   4935:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij);  
                   4936:     
                   4937:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   4938:     
                   4939:     printf("%d|",(int)age);fflush(stdout);
                   4940:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   4941:     
                   4942:     /* Computing expectancies */
                   4943:     for(i=1; i<=nlstate;i++)
                   4944:       for(j=1; j<=nlstate;j++)
                   4945:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   4946:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   4947:          
                   4948:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   4949: 
                   4950:        }
                   4951: 
                   4952:     fprintf(ficreseij,"%3.0f",age );
                   4953:     for(i=1; i<=nlstate;i++){
                   4954:       eip=0;
                   4955:       for(j=1; j<=nlstate;j++){
                   4956:        eip +=eij[i][j][(int)age];
                   4957:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   4958:       }
                   4959:       fprintf(ficreseij,"%9.4f", eip );
                   4960:     }
                   4961:     fprintf(ficreseij,"\n");
                   4962:     
                   4963:   }
                   4964:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   4965:   printf("\n");
                   4966:   fprintf(ficlog,"\n");
                   4967:   
                   4968: }
                   4969: 
1.127     brouard  4970: void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[] )
1.126     brouard  4971: 
                   4972: {
                   4973:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  4974:      to initial status i, ei. .
1.126     brouard  4975:   */
                   4976:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   4977:   int nhstepma, nstepma; /* Decreasing with age */
                   4978:   double age, agelim, hf;
                   4979:   double ***p3matp, ***p3matm, ***varhe;
                   4980:   double **dnewm,**doldm;
                   4981:   double *xp, *xm;
                   4982:   double **gp, **gm;
                   4983:   double ***gradg, ***trgradg;
                   4984:   int theta;
                   4985: 
                   4986:   double eip, vip;
                   4987: 
                   4988:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   4989:   xp=vector(1,npar);
                   4990:   xm=vector(1,npar);
                   4991:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   4992:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   4993:   
                   4994:   pstamp(ficresstdeij);
                   4995:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   4996:   fprintf(ficresstdeij,"# Age");
                   4997:   for(i=1; i<=nlstate;i++){
                   4998:     for(j=1; j<=nlstate;j++)
                   4999:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5000:     fprintf(ficresstdeij," e%1d. ",i);
                   5001:   }
                   5002:   fprintf(ficresstdeij,"\n");
                   5003: 
                   5004:   pstamp(ficrescveij);
                   5005:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5006:   fprintf(ficrescveij,"# Age");
                   5007:   for(i=1; i<=nlstate;i++)
                   5008:     for(j=1; j<=nlstate;j++){
                   5009:       cptj= (j-1)*nlstate+i;
                   5010:       for(i2=1; i2<=nlstate;i2++)
                   5011:        for(j2=1; j2<=nlstate;j2++){
                   5012:          cptj2= (j2-1)*nlstate+i2;
                   5013:          if(cptj2 <= cptj)
                   5014:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5015:        }
                   5016:     }
                   5017:   fprintf(ficrescveij,"\n");
                   5018:   
                   5019:   if(estepm < stepm){
                   5020:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5021:   }
                   5022:   else  hstepm=estepm;   
                   5023:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5024:    * This is mainly to measure the difference between two models: for example
                   5025:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5026:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5027:    * progression in between and thus overestimating or underestimating according
                   5028:    * to the curvature of the survival function. If, for the same date, we 
                   5029:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5030:    * to compare the new estimate of Life expectancy with the same linear 
                   5031:    * hypothesis. A more precise result, taking into account a more precise
                   5032:    * curvature will be obtained if estepm is as small as stepm. */
                   5033: 
                   5034:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5035:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5036:      nhstepm is the number of hstepm from age to agelim 
                   5037:      nstepm is the number of stepm from age to agelin. 
                   5038:      Look at hpijx to understand the reason of that which relies in memory size
                   5039:      and note for a fixed period like estepm months */
                   5040:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5041:      survival function given by stepm (the optimization length). Unfortunately it
                   5042:      means that if the survival funtion is printed only each two years of age and if
                   5043:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5044:      results. So we changed our mind and took the option of the best precision.
                   5045:   */
                   5046:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5047: 
                   5048:   /* If stepm=6 months */
                   5049:   /* nhstepm age range expressed in number of stepm */
                   5050:   agelim=AGESUP;
                   5051:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5052:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5053:   /* if (stepm >= YEARM) hstepm=1;*/
                   5054:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5055:   
                   5056:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5057:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5058:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5059:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5060:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5061:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5062: 
                   5063:   for (age=bage; age<=fage; age ++){ 
                   5064:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5065:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5066:     /* if (stepm >= YEARM) hstepm=1;*/
                   5067:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5068:                
1.126     brouard  5069:     /* If stepm=6 months */
                   5070:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5071:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5072:     
                   5073:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5074:                
1.126     brouard  5075:     /* Computing  Variances of health expectancies */
                   5076:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5077:        decrease memory allocation */
                   5078:     for(theta=1; theta <=npar; theta++){
                   5079:       for(i=1; i<=npar; i++){ 
1.222     brouard  5080:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5081:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5082:       }
                   5083:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij);  
                   5084:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij);  
1.218     brouard  5085:                        
1.126     brouard  5086:       for(j=1; j<= nlstate; j++){
1.222     brouard  5087:        for(i=1; i<=nlstate; i++){
                   5088:          for(h=0; h<=nhstepm-1; h++){
                   5089:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5090:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5091:          }
                   5092:        }
1.126     brouard  5093:       }
1.218     brouard  5094:                        
1.126     brouard  5095:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5096:        for(h=0; h<=nhstepm-1; h++){
                   5097:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5098:        }
1.126     brouard  5099:     }/* End theta */
                   5100:     
                   5101:     
                   5102:     for(h=0; h<=nhstepm-1; h++)
                   5103:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5104:        for(theta=1; theta <=npar; theta++)
                   5105:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5106:     
1.218     brouard  5107:                
1.222     brouard  5108:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5109:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5110:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5111:                
1.222     brouard  5112:     printf("%d|",(int)age);fflush(stdout);
                   5113:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5114:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5115:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5116:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5117:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5118:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5119:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5120:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5121:       }
                   5122:     }
1.218     brouard  5123:                
1.126     brouard  5124:     /* Computing expectancies */
                   5125:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij);  
                   5126:     for(i=1; i<=nlstate;i++)
                   5127:       for(j=1; j<=nlstate;j++)
1.222     brouard  5128:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5129:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5130:                                        
1.222     brouard  5131:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5132:                                        
1.222     brouard  5133:        }
1.218     brouard  5134:                
1.126     brouard  5135:     fprintf(ficresstdeij,"%3.0f",age );
                   5136:     for(i=1; i<=nlstate;i++){
                   5137:       eip=0.;
                   5138:       vip=0.;
                   5139:       for(j=1; j<=nlstate;j++){
1.222     brouard  5140:        eip += eij[i][j][(int)age];
                   5141:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5142:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5143:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5144:       }
                   5145:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5146:     }
                   5147:     fprintf(ficresstdeij,"\n");
1.218     brouard  5148:                
1.126     brouard  5149:     fprintf(ficrescveij,"%3.0f",age );
                   5150:     for(i=1; i<=nlstate;i++)
                   5151:       for(j=1; j<=nlstate;j++){
1.222     brouard  5152:        cptj= (j-1)*nlstate+i;
                   5153:        for(i2=1; i2<=nlstate;i2++)
                   5154:          for(j2=1; j2<=nlstate;j2++){
                   5155:            cptj2= (j2-1)*nlstate+i2;
                   5156:            if(cptj2 <= cptj)
                   5157:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5158:          }
1.126     brouard  5159:       }
                   5160:     fprintf(ficrescveij,"\n");
1.218     brouard  5161:                
1.126     brouard  5162:   }
                   5163:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5164:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5165:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5166:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5167:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5168:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5169:   printf("\n");
                   5170:   fprintf(ficlog,"\n");
1.218     brouard  5171:        
1.126     brouard  5172:   free_vector(xm,1,npar);
                   5173:   free_vector(xp,1,npar);
                   5174:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5175:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5176:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5177: }
1.218     brouard  5178:  
1.126     brouard  5179: /************ Variance ******************/
1.209     brouard  5180:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[])
1.218     brouard  5181:  {
                   5182:    /* Variance of health expectancies */
                   5183:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5184:    /* double **newm;*/
                   5185:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5186:   
                   5187:    /* int movingaverage(); */
                   5188:    double **dnewm,**doldm;
                   5189:    double **dnewmp,**doldmp;
                   5190:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5191:    int k;
                   5192:    double *xp;
                   5193:    double **gp, **gm;  /* for var eij */
                   5194:    double ***gradg, ***trgradg; /*for var eij */
                   5195:    double **gradgp, **trgradgp; /* for var p point j */
                   5196:    double *gpp, *gmp; /* for var p point j */
                   5197:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5198:    double ***p3mat;
                   5199:    double age,agelim, hf;
                   5200:    /* double ***mobaverage; */
                   5201:    int theta;
                   5202:    char digit[4];
                   5203:    char digitp[25];
                   5204: 
                   5205:    char fileresprobmorprev[FILENAMELENGTH];
                   5206: 
                   5207:    if(popbased==1){
                   5208:      if(mobilav!=0)
                   5209:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5210:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5211:    }
                   5212:    else 
                   5213:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5214: 
1.218     brouard  5215:    /* if (mobilav!=0) { */
                   5216:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5217:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5218:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5219:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5220:    /*   } */
                   5221:    /* } */
                   5222: 
                   5223:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5224:    sprintf(digit,"%-d",ij);
                   5225:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5226:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5227:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5228:    strcat(fileresprobmorprev,fileresu);
                   5229:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5230:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5231:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5232:    }
                   5233:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5234:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5235:    pstamp(ficresprobmorprev);
                   5236:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
                   5237:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5238:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5239:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5240:      for(i=1; i<=nlstate;i++)
                   5241:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5242:    }  
                   5243:    fprintf(ficresprobmorprev,"\n");
                   5244:   
                   5245:    fprintf(ficgp,"\n# Routine varevsij");
                   5246:    fprintf(ficgp,"\nunset title \n");
                   5247:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5248:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5249:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5250:    /*   } */
                   5251:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5252:    pstamp(ficresvij);
                   5253:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5254:    if(popbased==1)
                   5255:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5256:    else
                   5257:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5258:    fprintf(ficresvij,"# Age");
                   5259:    for(i=1; i<=nlstate;i++)
                   5260:      for(j=1; j<=nlstate;j++)
                   5261:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5262:    fprintf(ficresvij,"\n");
                   5263: 
                   5264:    xp=vector(1,npar);
                   5265:    dnewm=matrix(1,nlstate,1,npar);
                   5266:    doldm=matrix(1,nlstate,1,nlstate);
                   5267:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5268:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5269: 
                   5270:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5271:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5272:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5273:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5274:   
1.218     brouard  5275:    if(estepm < stepm){
                   5276:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5277:    }
                   5278:    else  hstepm=estepm;   
                   5279:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5280:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5281:       nhstepm is the number of hstepm from age to agelim 
                   5282:       nstepm is the number of stepm from age to agelim. 
                   5283:       Look at function hpijx to understand why because of memory size limitations, 
                   5284:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5285:       survival function given by stepm (the optimization length). Unfortunately it
                   5286:       means that if the survival funtion is printed every two years of age and if
                   5287:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5288:       results. So we changed our mind and took the option of the best precision.
                   5289:    */
                   5290:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5291:    agelim = AGESUP;
                   5292:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5293:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5294:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5295:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5296:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5297:      gp=matrix(0,nhstepm,1,nlstate);
                   5298:      gm=matrix(0,nhstepm,1,nlstate);
                   5299:                
                   5300:                
                   5301:      for(theta=1; theta <=npar; theta++){
                   5302:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5303:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5304:        }
                   5305:                        
                   5306:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij);
                   5307:                        
                   5308:        if (popbased==1) {
                   5309:         if(mobilav ==0){
                   5310:           for(i=1; i<=nlstate;i++)
                   5311:             prlim[i][i]=probs[(int)age][i][ij];
                   5312:         }else{ /* mobilav */ 
                   5313:           for(i=1; i<=nlstate;i++)
                   5314:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5315:         }
                   5316:        }
                   5317:                        
                   5318:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
                   5319:        for(j=1; j<= nlstate; j++){
                   5320:         for(h=0; h<=nhstepm; h++){
                   5321:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5322:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5323:         }
                   5324:        }
                   5325:        /* Next for computing probability of death (h=1 means
                   5326:          computed over hstepm matrices product = hstepm*stepm months) 
                   5327:          as a weighted average of prlim.
                   5328:        */
                   5329:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5330:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5331:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5332:        }    
                   5333:        /* end probability of death */
                   5334:                        
                   5335:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5336:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5337:                        
                   5338:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij);
                   5339:                        
                   5340:        if (popbased==1) {
                   5341:         if(mobilav ==0){
                   5342:           for(i=1; i<=nlstate;i++)
                   5343:             prlim[i][i]=probs[(int)age][i][ij];
                   5344:         }else{ /* mobilav */ 
                   5345:           for(i=1; i<=nlstate;i++)
                   5346:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5347:         }
                   5348:        }
                   5349:                        
                   5350:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);  
                   5351:                        
                   5352:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5353:         for(h=0; h<=nhstepm; h++){
                   5354:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5355:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5356:         }
                   5357:        }
                   5358:        /* This for computing probability of death (h=1 means
                   5359:          computed over hstepm matrices product = hstepm*stepm months) 
                   5360:          as a weighted average of prlim.
                   5361:        */
                   5362:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5363:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5364:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5365:        }    
                   5366:        /* end probability of death */
                   5367:                        
                   5368:        for(j=1; j<= nlstate; j++) /* vareij */
                   5369:         for(h=0; h<=nhstepm; h++){
                   5370:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5371:         }
                   5372:                        
                   5373:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5374:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5375:        }
                   5376:                        
                   5377:      } /* End theta */
                   5378:                
                   5379:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5380:                
                   5381:      for(h=0; h<=nhstepm; h++) /* veij */
                   5382:        for(j=1; j<=nlstate;j++)
                   5383:         for(theta=1; theta <=npar; theta++)
                   5384:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5385:                
                   5386:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5387:        for(theta=1; theta <=npar; theta++)
                   5388:         trgradgp[j][theta]=gradgp[theta][j];
                   5389:                
                   5390:                
                   5391:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5392:      for(i=1;i<=nlstate;i++)
                   5393:        for(j=1;j<=nlstate;j++)
                   5394:         vareij[i][j][(int)age] =0.;
                   5395:                
                   5396:      for(h=0;h<=nhstepm;h++){
                   5397:        for(k=0;k<=nhstepm;k++){
                   5398:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5399:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5400:         for(i=1;i<=nlstate;i++)
                   5401:           for(j=1;j<=nlstate;j++)
                   5402:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5403:        }
                   5404:      }
                   5405:                
                   5406:      /* pptj */
                   5407:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5408:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5409:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5410:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5411:         varppt[j][i]=doldmp[j][i];
                   5412:      /* end ppptj */
                   5413:      /*  x centered again */
                   5414:                
                   5415:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij);
                   5416:                
                   5417:      if (popbased==1) {
                   5418:        if(mobilav ==0){
                   5419:         for(i=1; i<=nlstate;i++)
                   5420:           prlim[i][i]=probs[(int)age][i][ij];
                   5421:        }else{ /* mobilav */ 
                   5422:         for(i=1; i<=nlstate;i++)
                   5423:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   5424:        }
                   5425:      }
                   5426:                
                   5427:      /* This for computing probability of death (h=1 means
                   5428:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   5429:        as a weighted average of prlim.
                   5430:      */
                   5431:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij);  
                   5432:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5433:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   5434:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   5435:      }    
                   5436:      /* end probability of death */
                   5437:                
                   5438:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   5439:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5440:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   5441:        for(i=1; i<=nlstate;i++){
                   5442:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   5443:        }
                   5444:      } 
                   5445:      fprintf(ficresprobmorprev,"\n");
                   5446:                
                   5447:      fprintf(ficresvij,"%.0f ",age );
                   5448:      for(i=1; i<=nlstate;i++)
                   5449:        for(j=1; j<=nlstate;j++){
                   5450:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   5451:        }
                   5452:      fprintf(ficresvij,"\n");
                   5453:      free_matrix(gp,0,nhstepm,1,nlstate);
                   5454:      free_matrix(gm,0,nhstepm,1,nlstate);
                   5455:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   5456:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   5457:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5458:    } /* End age */
                   5459:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   5460:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   5461:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   5462:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   5463:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   5464:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   5465:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   5466:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   5467:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5468:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   5469:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5470:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5471:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   5472:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   5473:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   5474:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   5475:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5476:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  5477:     */
1.218     brouard  5478:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   5479:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  5480: 
1.218     brouard  5481:    free_vector(xp,1,npar);
                   5482:    free_matrix(doldm,1,nlstate,1,nlstate);
                   5483:    free_matrix(dnewm,1,nlstate,1,npar);
                   5484:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5485:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   5486:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5487:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5488:    fclose(ficresprobmorprev);
                   5489:    fflush(ficgp);
                   5490:    fflush(fichtm); 
                   5491:  }  /* end varevsij */
1.126     brouard  5492: 
                   5493: /************ Variance of prevlim ******************/
1.209     brouard  5494:  void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[])
1.126     brouard  5495: {
1.205     brouard  5496:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  5497:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  5498: 
1.126     brouard  5499:   double **dnewm,**doldm;
                   5500:   int i, j, nhstepm, hstepm;
                   5501:   double *xp;
                   5502:   double *gp, *gm;
                   5503:   double **gradg, **trgradg;
1.208     brouard  5504:   double **mgm, **mgp;
1.126     brouard  5505:   double age,agelim;
                   5506:   int theta;
                   5507:   
                   5508:   pstamp(ficresvpl);
                   5509:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
                   5510:   fprintf(ficresvpl,"# Age");
                   5511:   for(i=1; i<=nlstate;i++)
                   5512:       fprintf(ficresvpl," %1d-%1d",i,i);
                   5513:   fprintf(ficresvpl,"\n");
                   5514: 
                   5515:   xp=vector(1,npar);
                   5516:   dnewm=matrix(1,nlstate,1,npar);
                   5517:   doldm=matrix(1,nlstate,1,nlstate);
                   5518:   
                   5519:   hstepm=1*YEARM; /* Every year of age */
                   5520:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   5521:   agelim = AGESUP;
                   5522:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5523:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5524:     if (stepm >= YEARM) hstepm=1;
                   5525:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   5526:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  5527:     mgp=matrix(1,npar,1,nlstate);
                   5528:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  5529:     gp=vector(1,nlstate);
                   5530:     gm=vector(1,nlstate);
                   5531: 
                   5532:     for(theta=1; theta <=npar; theta++){
                   5533:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   5534:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5535:       }
1.209     brouard  5536:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
                   5537:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij);
                   5538:       else
                   5539:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij);
1.208     brouard  5540:       for(i=1;i<=nlstate;i++){
1.126     brouard  5541:        gp[i] = prlim[i][i];
1.208     brouard  5542:        mgp[theta][i] = prlim[i][i];
                   5543:       }
1.126     brouard  5544:       for(i=1; i<=npar; i++) /* Computes gradient */
                   5545:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  5546:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
                   5547:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij);
                   5548:       else
                   5549:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij);
1.208     brouard  5550:       for(i=1;i<=nlstate;i++){
1.126     brouard  5551:        gm[i] = prlim[i][i];
1.208     brouard  5552:        mgm[theta][i] = prlim[i][i];
                   5553:       }
1.126     brouard  5554:       for(i=1;i<=nlstate;i++)
                   5555:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  5556:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  5557:     } /* End theta */
                   5558: 
                   5559:     trgradg =matrix(1,nlstate,1,npar);
                   5560: 
                   5561:     for(j=1; j<=nlstate;j++)
                   5562:       for(theta=1; theta <=npar; theta++)
                   5563:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  5564:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5565:     /*   printf("\nmgm mgp %d ",(int)age); */
                   5566:     /*   for(j=1; j<=nlstate;j++){ */
                   5567:     /*         printf(" %d ",j); */
                   5568:     /*         for(theta=1; theta <=npar; theta++) */
                   5569:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   5570:     /*         printf("\n "); */
                   5571:     /*   } */
                   5572:     /* } */
                   5573:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5574:     /*   printf("\n gradg %d ",(int)age); */
                   5575:     /*   for(j=1; j<=nlstate;j++){ */
                   5576:     /*         printf("%d ",j); */
                   5577:     /*         for(theta=1; theta <=npar; theta++) */
                   5578:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   5579:     /*         printf("\n "); */
                   5580:     /*   } */
                   5581:     /* } */
1.126     brouard  5582: 
                   5583:     for(i=1;i<=nlstate;i++)
                   5584:       varpl[i][(int)age] =0.;
1.209     brouard  5585:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.205     brouard  5586:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   5587:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
                   5588:     }else{
1.126     brouard  5589:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   5590:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  5591:     }
1.126     brouard  5592:     for(i=1;i<=nlstate;i++)
                   5593:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   5594: 
                   5595:     fprintf(ficresvpl,"%.0f ",age );
                   5596:     for(i=1; i<=nlstate;i++)
                   5597:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   5598:     fprintf(ficresvpl,"\n");
                   5599:     free_vector(gp,1,nlstate);
                   5600:     free_vector(gm,1,nlstate);
1.208     brouard  5601:     free_matrix(mgm,1,npar,1,nlstate);
                   5602:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  5603:     free_matrix(gradg,1,npar,1,nlstate);
                   5604:     free_matrix(trgradg,1,nlstate,1,npar);
                   5605:   } /* End age */
                   5606: 
                   5607:   free_vector(xp,1,npar);
                   5608:   free_matrix(doldm,1,nlstate,1,npar);
                   5609:   free_matrix(dnewm,1,nlstate,1,nlstate);
                   5610: 
                   5611: }
                   5612: 
                   5613: /************ Variance of one-step probabilities  ******************/
                   5614: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  5615:  {
                   5616:    int i, j=0,  k1, l1, tj;
                   5617:    int k2, l2, j1,  z1;
                   5618:    int k=0, l;
                   5619:    int first=1, first1, first2;
                   5620:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   5621:    double **dnewm,**doldm;
                   5622:    double *xp;
                   5623:    double *gp, *gm;
                   5624:    double **gradg, **trgradg;
                   5625:    double **mu;
                   5626:    double age, cov[NCOVMAX+1];
                   5627:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   5628:    int theta;
                   5629:    char fileresprob[FILENAMELENGTH];
                   5630:    char fileresprobcov[FILENAMELENGTH];
                   5631:    char fileresprobcor[FILENAMELENGTH];
                   5632:    double ***varpij;
                   5633: 
                   5634:    strcpy(fileresprob,"PROB_"); 
                   5635:    strcat(fileresprob,fileres);
                   5636:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   5637:      printf("Problem with resultfile: %s\n", fileresprob);
                   5638:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   5639:    }
                   5640:    strcpy(fileresprobcov,"PROBCOV_"); 
                   5641:    strcat(fileresprobcov,fileresu);
                   5642:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   5643:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   5644:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   5645:    }
                   5646:    strcpy(fileresprobcor,"PROBCOR_"); 
                   5647:    strcat(fileresprobcor,fileresu);
                   5648:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   5649:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   5650:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   5651:    }
                   5652:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   5653:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   5654:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   5655:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   5656:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   5657:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   5658:    pstamp(ficresprob);
                   5659:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   5660:    fprintf(ficresprob,"# Age");
                   5661:    pstamp(ficresprobcov);
                   5662:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   5663:    fprintf(ficresprobcov,"# Age");
                   5664:    pstamp(ficresprobcor);
                   5665:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   5666:    fprintf(ficresprobcor,"# Age");
1.126     brouard  5667: 
                   5668: 
1.222     brouard  5669:    for(i=1; i<=nlstate;i++)
                   5670:      for(j=1; j<=(nlstate+ndeath);j++){
                   5671:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   5672:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   5673:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   5674:      }  
                   5675:    /* fprintf(ficresprob,"\n");
                   5676:       fprintf(ficresprobcov,"\n");
                   5677:       fprintf(ficresprobcor,"\n");
                   5678:    */
                   5679:    xp=vector(1,npar);
                   5680:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   5681:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   5682:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   5683:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   5684:    first=1;
                   5685:    fprintf(ficgp,"\n# Routine varprob");
                   5686:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   5687:    fprintf(fichtm,"\n");
                   5688: 
                   5689:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.</li>\n",optionfilehtmcov);
                   5690:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   5691:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  5692: and drawn. It helps understanding how is the covariance between two incidences.\
                   5693:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  5694:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  5695: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   5696: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   5697: standard deviations wide on each axis. <br>\
                   5698:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   5699:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   5700: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   5701: 
1.222     brouard  5702:    cov[1]=1;
                   5703:    /* tj=cptcoveff; */
1.225     brouard  5704:    tj = (int) pow(2,cptcoveff);
1.222     brouard  5705:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   5706:    j1=0;
1.224     brouard  5707:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  5708:      if  (cptcovn>0) {
                   5709:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  5710:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5711:        fprintf(ficresprob, "**********\n#\n");
                   5712:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  5713:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5714:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  5715:                        
1.222     brouard  5716:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  5717:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5718:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  5719:                        
                   5720:                        
1.222     brouard  5721:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  5722:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5723:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  5724:                        
1.222     brouard  5725:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  5726:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5727:        fprintf(ficresprobcor, "**********\n#");    
                   5728:        if(invalidvarcomb[j1]){
                   5729:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   5730:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   5731:         continue;
                   5732:        }
                   5733:      }
                   5734:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   5735:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   5736:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   5737:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   5738:      for (age=bage; age<=fage; age ++){ 
                   5739:        cov[2]=age;
                   5740:        if(nagesqr==1)
                   5741:         cov[3]= age*age;
                   5742:        for (k=1; k<=cptcovn;k++) {
                   5743:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   5744:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   5745:                                                                    * 1  1 1 1 1
                   5746:                                                                    * 2  2 1 1 1
                   5747:                                                                    * 3  1 2 1 1
                   5748:                                                                    */
                   5749:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   5750:        }
                   5751:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   5752:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   5753:        for (k=1; k<=cptcovprod;k++)
                   5754:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  5755:                        
                   5756:                        
1.222     brouard  5757:        for(theta=1; theta <=npar; theta++){
                   5758:         for(i=1; i<=npar; i++)
                   5759:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  5760:                                
1.222     brouard  5761:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  5762:                                
1.222     brouard  5763:         k=0;
                   5764:         for(i=1; i<= (nlstate); i++){
                   5765:           for(j=1; j<=(nlstate+ndeath);j++){
                   5766:             k=k+1;
                   5767:             gp[k]=pmmij[i][j];
                   5768:           }
                   5769:         }
1.220     brouard  5770:                                
1.222     brouard  5771:         for(i=1; i<=npar; i++)
                   5772:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  5773:                                
1.222     brouard  5774:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   5775:         k=0;
                   5776:         for(i=1; i<=(nlstate); i++){
                   5777:           for(j=1; j<=(nlstate+ndeath);j++){
                   5778:             k=k+1;
                   5779:             gm[k]=pmmij[i][j];
                   5780:           }
                   5781:         }
1.220     brouard  5782:                                
1.222     brouard  5783:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   5784:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   5785:        }
1.126     brouard  5786: 
1.222     brouard  5787:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   5788:         for(theta=1; theta <=npar; theta++)
                   5789:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  5790:                        
1.222     brouard  5791:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   5792:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  5793:                        
1.222     brouard  5794:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  5795:                        
1.222     brouard  5796:        k=0;
                   5797:        for(i=1; i<=(nlstate); i++){
                   5798:         for(j=1; j<=(nlstate+ndeath);j++){
                   5799:           k=k+1;
                   5800:           mu[k][(int) age]=pmmij[i][j];
                   5801:         }
                   5802:        }
                   5803:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   5804:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   5805:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  5806:                        
1.222     brouard  5807:        /*printf("\n%d ",(int)age);
                   5808:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   5809:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   5810:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   5811:         }*/
1.220     brouard  5812:                        
1.222     brouard  5813:        fprintf(ficresprob,"\n%d ",(int)age);
                   5814:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   5815:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  5816:                        
1.222     brouard  5817:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   5818:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   5819:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   5820:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   5821:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   5822:        }
                   5823:        i=0;
                   5824:        for (k=1; k<=(nlstate);k++){
                   5825:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   5826:           i++;
                   5827:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   5828:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   5829:           for (j=1; j<=i;j++){
                   5830:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   5831:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   5832:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   5833:           }
                   5834:         }
                   5835:        }/* end of loop for state */
                   5836:      } /* end of loop for age */
                   5837:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   5838:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   5839:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   5840:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   5841:     
                   5842:      /* Confidence intervalle of pij  */
                   5843:      /*
                   5844:        fprintf(ficgp,"\nunset parametric;unset label");
                   5845:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   5846:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   5847:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   5848:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   5849:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   5850:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   5851:      */
                   5852:                
                   5853:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   5854:      first1=1;first2=2;
                   5855:      for (k2=1; k2<=(nlstate);k2++){
                   5856:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   5857:         if(l2==k2) continue;
                   5858:         j=(k2-1)*(nlstate+ndeath)+l2;
                   5859:         for (k1=1; k1<=(nlstate);k1++){
                   5860:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   5861:             if(l1==k1) continue;
                   5862:             i=(k1-1)*(nlstate+ndeath)+l1;
                   5863:             if(i<=j) continue;
                   5864:             for (age=bage; age<=fage; age ++){ 
                   5865:               if ((int)age %5==0){
                   5866:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   5867:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   5868:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   5869:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   5870:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   5871:                 c12=cv12/sqrt(v1*v2);
                   5872:                 /* Computing eigen value of matrix of covariance */
                   5873:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   5874:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   5875:                 if ((lc2 <0) || (lc1 <0) ){
                   5876:                   if(first2==1){
                   5877:                     first1=0;
                   5878:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   5879:                   }
                   5880:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   5881:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   5882:                   /* lc2=fabs(lc2); */
                   5883:                 }
1.220     brouard  5884:                                                                
1.222     brouard  5885:                 /* Eigen vectors */
                   5886:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   5887:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   5888:                 v21=(lc1-v1)/cv12*v11;
                   5889:                 v12=-v21;
                   5890:                 v22=v11;
                   5891:                 tnalp=v21/v11;
                   5892:                 if(first1==1){
                   5893:                   first1=0;
                   5894:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   5895:                 }
                   5896:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   5897:                 /*printf(fignu*/
                   5898:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   5899:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   5900:                 if(first==1){
                   5901:                   first=0;
                   5902:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   5903:                   fprintf(ficgp,"\nset parametric;unset label");
                   5904:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   5905:                   fprintf(ficgp,"\nset ter svg size 640, 480");
                   5906:                   fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  5907:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  5908: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  5909:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   5910:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   5911:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   5912:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   5913:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   5914:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   5915:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   5916:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
                   5917:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                                                         \
                   5918:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   5919:                 }else{
                   5920:                   first=0;
                   5921:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   5922:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   5923:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   5924:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
                   5925:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                 \
                   5926:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   5927:                 }/* if first */
                   5928:               } /* age mod 5 */
                   5929:             } /* end loop age */
                   5930:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   5931:             first=1;
                   5932:           } /*l12 */
                   5933:         } /* k12 */
                   5934:        } /*l1 */
                   5935:      }/* k1 */
                   5936:    }  /* loop on combination of covariates j1 */
                   5937:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   5938:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   5939:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   5940:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   5941:    free_vector(xp,1,npar);
                   5942:    fclose(ficresprob);
                   5943:    fclose(ficresprobcov);
                   5944:    fclose(ficresprobcor);
                   5945:    fflush(ficgp);
                   5946:    fflush(fichtmcov);
                   5947:  }
1.126     brouard  5948: 
                   5949: 
                   5950: /******************* Printing html file ***********/
1.201     brouard  5951: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  5952:                  int lastpass, int stepm, int weightopt, char model[],\
                   5953:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.217     brouard  5954:                  int popforecast, int prevfcast, int backcast, int estepm , \
1.213     brouard  5955:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   5956:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.126     brouard  5957:   int jj1, k1, i1, cpt;
                   5958: 
                   5959:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   5960:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   5961: </ul>");
1.214     brouard  5962:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   5963:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   5964:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   5965:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  5966:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   5967:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  5968:    fprintf(fichtm,"\
                   5969:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  5970:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  5971:    fprintf(fichtm,"\
1.217     brouard  5972:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   5973:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   5974:    fprintf(fichtm,"\
1.126     brouard  5975:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  5976:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  5977:    fprintf(fichtm,"\
1.217     brouard  5978:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   5979:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   5980:    fprintf(fichtm,"\
1.211     brouard  5981:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  5982:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  5983:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  5984:    if(prevfcast==1){
                   5985:      fprintf(fichtm,"\
                   5986:  - Prevalence projections by age and states:                           \
1.201     brouard  5987:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  5988:    }
1.126     brouard  5989: 
1.222     brouard  5990:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
1.126     brouard  5991: 
1.225     brouard  5992:    m=pow(2,cptcoveff);
1.222     brouard  5993:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  5994: 
1.222     brouard  5995:    jj1=0;
                   5996:    for(k1=1; k1<=m;k1++){
1.220     brouard  5997: 
1.222     brouard  5998:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   5999:      jj1++;
                   6000:      if (cptcovn > 0) {
                   6001:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6002:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.222     brouard  6003:         fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);
                   6004:         printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout);
                   6005:        }
1.230     brouard  6006:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6007:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6008:        if(invalidvarcomb[k1]){
                   6009:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6010:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6011:         continue;
                   6012:        }
                   6013:      }
                   6014:      /* aij, bij */
                   6015:      fprintf(fichtm,"<br>- Logit model (yours is: 1+age+%s), for example: logit(pij)=log(pij/pii)= aij+ bij age + V1 age + etc. as a function of age: <a href=\"%s_%d-1.svg\">%s_%d-1.svg</a><br> \
1.211     brouard  6016: <img src=\"%s_%d-1.svg\">",model,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1);
1.222     brouard  6017:      /* Pij */
                   6018:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2.svg\">%s_%d-2.svg</a><br> \
1.201     brouard  6019: <img src=\"%s_%d-2.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1);     
1.222     brouard  6020:      /* Quasi-incidences */
                   6021:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6022:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6023:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
                   6024: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3.svg\">%s_%d-3.svg</a><br> \
1.201     brouard  6025: <img src=\"%s_%d-3.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1); 
1.222     brouard  6026:      /* Survival functions (period) in state j */
                   6027:      for(cpt=1; cpt<=nlstate;cpt++){
                   6028:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> \
1.201     brouard  6029: <img src=\"%s_%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,jj1,subdirf2(optionfilefiname,"LIJ_"),cpt,jj1,subdirf2(optionfilefiname,"LIJ_"),cpt,jj1);
1.222     brouard  6030:      }
                   6031:      /* State specific survival functions (period) */
                   6032:      for(cpt=1; cpt<=nlstate;cpt++){
                   6033:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6034:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.201     brouard  6035:  <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> <img src=\"%s_%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,jj1,subdirf2(optionfilefiname,"LIJT_"),cpt,jj1,subdirf2(optionfilefiname,"LIJT_"),cpt,jj1);
1.222     brouard  6036:      }
                   6037:      /* Period (stable) prevalence in each health state */
                   6038:      for(cpt=1; cpt<=nlstate;cpt++){
                   6039:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a><br> \
1.201     brouard  6040: <img src=\"%s_%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,jj1,subdirf2(optionfilefiname,"P_"),cpt,jj1,subdirf2(optionfilefiname,"P_"),cpt,jj1);
1.222     brouard  6041:      }
                   6042:      if(backcast==1){
                   6043:        /* Period (stable) back prevalence in each health state */
                   6044:        for(cpt=1; cpt<=nlstate;cpt++){
                   6045:         fprintf(fichtm,"<br>\n- Convergence to period (stable) back prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a><br> \
1.217     brouard  6046: <img src=\"%s_%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,jj1,subdirf2(optionfilefiname,"PB_"),cpt,jj1,subdirf2(optionfilefiname,"PB_"),cpt,jj1);
1.222     brouard  6047:        }
1.217     brouard  6048:      }
1.222     brouard  6049:      if(prevfcast==1){
                   6050:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6051:        for(cpt=1; cpt<=nlstate;cpt++){
                   6052:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f) up to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> \
1.213     brouard  6053: <img src=\"%s_%d-%d.svg\">", dateprev1, dateprev2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,jj1,subdirf2(optionfilefiname,"PROJ_"),cpt,jj1,subdirf2(optionfilefiname,"PROJ_"),cpt,jj1);
1.222     brouard  6054:        }
                   6055:      }
1.220     brouard  6056:         
1.222     brouard  6057:      for(cpt=1; cpt<=nlstate;cpt++) {
                   6058:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d%d.svg\">%s_%d%d.svg</a> <br> \
1.201     brouard  6059: <img src=\"%s_%d%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,jj1,subdirf2(optionfilefiname,"EXP_"),cpt,jj1,subdirf2(optionfilefiname,"EXP_"),cpt,jj1);
1.222     brouard  6060:      }
                   6061:      /* } /\* end i1 *\/ */
                   6062:    }/* End k1 */
                   6063:    fprintf(fichtm,"</ul>");
1.126     brouard  6064: 
1.222     brouard  6065:    fprintf(fichtm,"\
1.126     brouard  6066: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6067:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6068:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6069: But because parameters are usually highly correlated (a higher incidence of disability \
                   6070: and a higher incidence of recovery can give very close observed transition) it might \
                   6071: be very useful to look not only at linear confidence intervals estimated from the \
                   6072: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6073: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6074: covariance matrix of the one-step probabilities. \
                   6075: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6076: 
1.222     brouard  6077:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6078:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6079:    fprintf(fichtm,"\
1.126     brouard  6080:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6081:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6082: 
1.222     brouard  6083:    fprintf(fichtm,"\
1.126     brouard  6084:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6085:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6086:    fprintf(fichtm,"\
1.126     brouard  6087:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6088:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6089:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6090:    fprintf(fichtm,"\
1.126     brouard  6091:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6092:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6093:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6094:    fprintf(fichtm,"\
1.128     brouard  6095:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6096:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6097:    fprintf(fichtm,"\
1.128     brouard  6098:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6099:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6100:    fprintf(fichtm,"\
1.126     brouard  6101:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6102:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6103: 
                   6104: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6105: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6106: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6107: /*     <br>",fileres,fileres,fileres,fileres); */
                   6108: /*  else  */
                   6109: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6110:    fflush(fichtm);
                   6111:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6112: 
1.225     brouard  6113:    m=pow(2,cptcoveff);
1.222     brouard  6114:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6115: 
1.222     brouard  6116:    jj1=0;
                   6117:    for(k1=1; k1<=m;k1++){
                   6118:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6119:      jj1++;
1.126     brouard  6120:      if (cptcovn > 0) {
                   6121:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6122:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.222     brouard  6123:         fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);
1.126     brouard  6124:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6125: 
1.222     brouard  6126:        if(invalidvarcomb[k1]){
                   6127:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6128:         continue;
                   6129:        }
1.126     brouard  6130:      }
                   6131:      for(cpt=1; cpt<=nlstate;cpt++) {
1.218     brouard  6132:        fprintf(fichtm,"\n<br>- Observed (cross-sectional) and period (incidence based) \
                   6133: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d.svg\"> %s_%d-%d.svg</a>\n <br>\
1.205     brouard  6134: <img src=\"%s_%d-%d.svg\">",cpt,subdirf2(optionfilefiname,"V_"),cpt,jj1,subdirf2(optionfilefiname,"V_"),cpt,jj1,subdirf2(optionfilefiname,"V_"),cpt,jj1);  
1.126     brouard  6135:      }
                   6136:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6137: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6138: true period expectancies (those weighted with period prevalences are also\
                   6139:  drawn in addition to the population based expectancies computed using\
1.218     brouard  6140:  observed and cahotic prevalences:  <a href=\"%s_%d.svg\">%s_%d.svg</a>\n<br>\
1.205     brouard  6141: <img src=\"%s_%d.svg\">",subdirf2(optionfilefiname,"E_"),jj1,subdirf2(optionfilefiname,"E_"),jj1,subdirf2(optionfilefiname,"E_"),jj1);
1.222     brouard  6142:      /* } /\* end i1 *\/ */
                   6143:    }/* End k1 */
                   6144:    fprintf(fichtm,"</ul>");
                   6145:    fflush(fichtm);
1.126     brouard  6146: }
                   6147: 
                   6148: /******************* Gnuplot file **************/
1.223     brouard  6149: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[]){
1.126     brouard  6150: 
                   6151:   char dirfileres[132],optfileres[132];
1.223     brouard  6152:   char gplotcondition[132];
1.164     brouard  6153:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,ij=0,l=0;
1.211     brouard  6154:   int lv=0, vlv=0, kl=0;
1.130     brouard  6155:   int ng=0;
1.201     brouard  6156:   int vpopbased;
1.223     brouard  6157:   int ioffset; /* variable offset for columns */
1.219     brouard  6158: 
1.126     brouard  6159: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6160: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6161: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6162: /*   } */
                   6163: 
                   6164:   /*#ifdef windows */
                   6165:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6166:   /*#endif */
1.225     brouard  6167:   m=pow(2,cptcoveff);
1.126     brouard  6168: 
1.202     brouard  6169:   /* Contribution to likelihood */
                   6170:   /* Plot the probability implied in the likelihood */
1.223     brouard  6171:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6172:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6173:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6174:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6175: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6176:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6177: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6178:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6179:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6180:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6181:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6182:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6183:   for (i=1; i<= nlstate ; i ++) {
                   6184:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6185:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6186:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6187:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6188:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6189:     }
                   6190:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6191:   }
                   6192:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6193:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6194:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6195:   fprintf(ficgp,"\nset out;unset log\n");
                   6196:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6197: 
1.126     brouard  6198:   strcpy(dirfileres,optionfilefiname);
                   6199:   strcpy(optfileres,"vpl");
1.223     brouard  6200:   /* 1eme*/
1.211     brouard  6201:   for (cpt=1; cpt<= nlstate ; cpt ++) { /* For each live state */
1.230     brouard  6202:     for (k1=1; k1<= m && selected(k1) ; k1 ++) { /* For each valid combination of covariate */
1.211     brouard  6203:       /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
                   6204:       fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files ");
1.225     brouard  6205:       for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6206:        lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
1.223     brouard  6207:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6208:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6209:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6210:        vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   6211:        /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
                   6212:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6213:       }
                   6214:       fprintf(ficgp,"\n#\n");
1.223     brouard  6215:       if(invalidvarcomb[k1]){
                   6216:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6217:        continue;
                   6218:       }
1.211     brouard  6219: 
1.223     brouard  6220:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1);
                   6221:       fprintf(ficgp,"\n#set out \"V_%s_%d-%d.svg\" \n",optionfilefiname,cpt,k1);
                   6222:       fprintf(ficgp,"set xlabel \"Age\" \n\
1.219     brouard  6223: set ylabel \"Probability\" \n  \
                   6224: set ter svg size 640, 480\n    \
1.201     brouard  6225: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:2 \"%%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1);
1.219     brouard  6226:                        
1.223     brouard  6227:       for (i=1; i<= nlstate ; i ++) {
                   6228:        if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6229:        else        fprintf(ficgp," %%*lf (%%*lf)");
                   6230:       }
                   6231:       fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2+1.96*$3) \"%%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1);
                   6232:       for (i=1; i<= nlstate ; i ++) {
                   6233:        if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6234:        else fprintf(ficgp," %%*lf (%%*lf)");
                   6235:       } 
                   6236:       fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2-1.96*$3) \"%%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1); 
                   6237:       for (i=1; i<= nlstate ; i ++) {
                   6238:        if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6239:        else fprintf(ficgp," %%*lf (%%*lf)");
                   6240:       }  
                   6241:       fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1));
                   6242:       if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   6243:        /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
                   6244:        fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1 */
1.225     brouard  6245:        if(cptcoveff ==0){
1.223     brouard  6246:          fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line ",  2+(cpt-1),  cpt );
                   6247:        }else{
                   6248:          kl=0;
1.225     brouard  6249:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   6250:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
1.223     brouard  6251:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6252:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6253:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6254:            vlv= nbcode[Tvaraff[k]][lv];
                   6255:            kl++;
                   6256:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6257:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6258:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6259:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
1.225     brouard  6260:            if(k==cptcoveff){
1.227     brouard  6261:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   6262:                      4+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.223     brouard  6263:            }else{
                   6264:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   6265:              kl++;
                   6266:            }
                   6267:          } /* end covariate */
                   6268:        } /* end if no covariate */
                   6269:       } /* end if backcast */
                   6270:       fprintf(ficgp,"\nset out \n");
1.201     brouard  6271:     } /* k1 */
                   6272:   } /* cpt */
1.126     brouard  6273:   /*2 eme*/
                   6274:   for (k1=1; k1<= m ; k1 ++) { 
1.220     brouard  6275: 
1.223     brouard  6276:     fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.225     brouard  6277:     for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6278:       lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6279:       /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6280:       /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6281:       /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6282:       vlv= nbcode[Tvaraff[k]][lv];
                   6283:       fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6284:     }
                   6285:     fprintf(ficgp,"\n#\n");
                   6286:     if(invalidvarcomb[k1]){
                   6287:       fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6288:       continue;
                   6289:     }
1.219     brouard  6290:                        
1.223     brouard  6291:     fprintf(ficgp,"\nset out \"%s_%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1);
                   6292:     for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
                   6293:       if(vpopbased==0)
                   6294:        fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
                   6295:       else
                   6296:        fprintf(ficgp,"\nreplot ");
                   6297:       for (i=1; i<= nlstate+1 ; i ++) {
                   6298:        k=2*i;
                   6299:        fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1, vpopbased);
                   6300:        for (j=1; j<= nlstate+1 ; j ++) {
                   6301:          if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6302:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6303:        }   
                   6304:        if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   6305:        else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
                   6306:        fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6307:        for (j=1; j<= nlstate+1 ; j ++) {
                   6308:          if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6309:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6310:        }   
                   6311:        fprintf(ficgp,"\" t\"\" w l lt 0,");
                   6312:        fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6313:        for (j=1; j<= nlstate+1 ; j ++) {
                   6314:          if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6315:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6316:        }   
                   6317:        if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   6318:        else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   6319:       } /* state */
                   6320:     } /* vpopbased */
                   6321:     fprintf(ficgp,"\nset out;set out \"%s_%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1); /* Buggy gnuplot */
1.201     brouard  6322:   } /* k1 */
1.219     brouard  6323:        
                   6324:        
1.126     brouard  6325:   /*3eme*/
                   6326:   for (k1=1; k1<= m ; k1 ++) { 
1.220     brouard  6327: 
1.126     brouard  6328:     for (cpt=1; cpt<= nlstate ; cpt ++) {
1.211     brouard  6329:       fprintf(ficgp,"\n# 3d: Life expectancy with EXP_ files:  cov=%d state=%d",k1, cpt);
1.225     brouard  6330:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6331:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6332:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6333:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6334:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6335:        vlv= nbcode[Tvaraff[k]][lv];
                   6336:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6337:       }
                   6338:       fprintf(ficgp,"\n#\n");
1.223     brouard  6339:       if(invalidvarcomb[k1]){
                   6340:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6341:        continue;
                   6342:       }
1.219     brouard  6343:                        
1.126     brouard  6344:       /*       k=2+nlstate*(2*cpt-2); */
                   6345:       k=2+(nlstate+1)*(cpt-1);
1.201     brouard  6346:       fprintf(ficgp,"\nset out \"%s_%d%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1);
1.199     brouard  6347:       fprintf(ficgp,"set ter svg size 640, 480\n\
1.201     brouard  6348: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),k1-1,k1-1,k,cpt);
1.126     brouard  6349:       /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
1.223     brouard  6350:        for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6351:        fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   6352:        fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6353:        for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6354:        fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  6355:                                
1.126     brouard  6356:       */
                   6357:       for (i=1; i< nlstate ; i ++) {
1.223     brouard  6358:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+i,cpt,i+1);
                   6359:        /*      fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  6360:                                
1.126     brouard  6361:       } 
1.201     brouard  6362:       fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+nlstate,cpt);
1.126     brouard  6363:     }
                   6364:   }
                   6365:   
1.223     brouard  6366:   /* 4eme */
1.201     brouard  6367:   /* Survival functions (period) from state i in state j by initial state i */
                   6368:   for (k1=1; k1<= m ; k1 ++) { /* For each multivariate if any */
1.220     brouard  6369: 
1.201     brouard  6370:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.211     brouard  6371:       fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
1.225     brouard  6372:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6373:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6374:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6375:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6376:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6377:        vlv= nbcode[Tvaraff[k]][lv];
                   6378:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6379:       }
                   6380:       fprintf(ficgp,"\n#\n");
1.223     brouard  6381:       if(invalidvarcomb[k1]){
                   6382:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6383:        continue;
                   6384:       }
1.220     brouard  6385:                        
1.201     brouard  6386:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1);
                   6387:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
1.220     brouard  6388: set ter svg size 640, 480\n                                                                                                                                                                                    \
                   6389: unset log y\n                                                                                                                                                                                                                                          \
1.201     brouard  6390: plot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6391:       k=3;
1.201     brouard  6392:       for (i=1; i<= nlstate ; i ++){
1.223     brouard  6393:        if(i==1){
                   6394:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6395:        }else{
                   6396:          fprintf(ficgp,", '' ");
                   6397:        }
                   6398:        l=(nlstate+ndeath)*(i-1)+1;
                   6399:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6400:        for (j=2; j<= nlstate+ndeath ; j ++)
                   6401:          fprintf(ficgp,"+$%d",k+l+j-1);
                   6402:        fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
1.201     brouard  6403:       } /* nlstate */
                   6404:       fprintf(ficgp,"\nset out\n");
                   6405:     } /* end cpt state*/ 
                   6406:   } /* end covariate */  
1.220     brouard  6407:        
                   6408: /* 5eme */
1.201     brouard  6409:   /* Survival functions (period) from state i in state j by final state j */
1.202     brouard  6410:   for (k1=1; k1<= m ; k1 ++) { /* For each covariate if any */
1.201     brouard  6411:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.223     brouard  6412:                        
1.201     brouard  6413:       fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
1.225     brouard  6414:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  6415:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6416:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6417:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6418:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6419:        vlv= nbcode[Tvaraff[k]][lv];
                   6420:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6421:       }
                   6422:       fprintf(ficgp,"\n#\n");
1.223     brouard  6423:       if(invalidvarcomb[k1]){
1.227     brouard  6424:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6425:        continue;
1.223     brouard  6426:       }
1.227     brouard  6427:       
1.201     brouard  6428:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1);
                   6429:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
1.227     brouard  6430: set ter svg size 640, 480\n                                            \
                   6431: unset log y\n                                                          \
1.201     brouard  6432: plot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6433:       k=3;
1.201     brouard  6434:       for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
1.227     brouard  6435:        if(j==1)
                   6436:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6437:        else
                   6438:          fprintf(ficgp,", '' ");
                   6439:        l=(nlstate+ndeath)*(cpt-1) +j;
                   6440:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   6441:        /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   6442:        /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   6443:        fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
1.201     brouard  6444:       } /* nlstate */
                   6445:       fprintf(ficgp,", '' ");
                   6446:       fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   6447:       for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
1.227     brouard  6448:        l=(nlstate+ndeath)*(cpt-1) +j;
                   6449:        if(j < nlstate)
                   6450:          fprintf(ficgp,"$%d +",k+l);
                   6451:        else
                   6452:          fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
1.201     brouard  6453:       }
                   6454:       fprintf(ficgp,"\nset out\n");
                   6455:     } /* end cpt state*/ 
                   6456:   } /* end covariate */  
1.227     brouard  6457:   
1.220     brouard  6458: /* 6eme */
1.202     brouard  6459:   /* CV preval stable (period) for each covariate */
1.211     brouard  6460:   for (k1=1; k1<= m ; k1 ++) { /* For each covariate combination (1 to m=2**k), if any covariate is present */
1.153     brouard  6461:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6462:       
1.211     brouard  6463:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  6464:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  6465:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6466:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6467:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6468:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6469:        vlv= nbcode[Tvaraff[k]][lv];
                   6470:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6471:       }
                   6472:       fprintf(ficgp,"\n#\n");
1.223     brouard  6473:       if(invalidvarcomb[k1]){
1.227     brouard  6474:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6475:        continue;
1.223     brouard  6476:       }
1.227     brouard  6477:       
1.201     brouard  6478:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1);
1.126     brouard  6479:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.227     brouard  6480: set ter svg size 640, 480\n                                            \
                   6481: unset log y\n                                                          \
1.153     brouard  6482: plot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6483:       k=3; /* Offset */
1.153     brouard  6484:       for (i=1; i<= nlstate ; i ++){
1.227     brouard  6485:        if(i==1)
                   6486:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6487:        else
                   6488:          fprintf(ficgp,", '' ");
                   6489:        l=(nlstate+ndeath)*(i-1)+1;
                   6490:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6491:        for (j=2; j<= nlstate ; j ++)
                   6492:          fprintf(ficgp,"+$%d",k+l+j-1);
                   6493:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  6494:       } /* nlstate */
1.201     brouard  6495:       fprintf(ficgp,"\nset out\n");
1.153     brouard  6496:     } /* end cpt state*/ 
                   6497:   } /* end covariate */  
1.227     brouard  6498:   
                   6499:   
1.220     brouard  6500: /* 7eme */
1.218     brouard  6501:   if(backcast == 1){
1.217     brouard  6502:     /* CV back preval stable (period) for each covariate */
1.218     brouard  6503:     for (k1=1; k1<= m ; k1 ++) { /* For each covariate combination (1 to m=2**k), if any covariate is present */
                   6504:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6505:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
                   6506:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6507:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6508:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6509:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  6510:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  6511:          vlv= nbcode[Tvaraff[k]][lv];
                   6512:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6513:        }
                   6514:        fprintf(ficgp,"\n#\n");
                   6515:        if(invalidvarcomb[k1]){
                   6516:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6517:          continue;
                   6518:        }
                   6519:        
                   6520:        fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1);
                   6521:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
                   6522: set ter svg size 640, 480\n                                            \
                   6523: unset log y\n                                                          \
1.218     brouard  6524: plot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  6525:        k=3; /* Offset */
                   6526:        for (i=1; i<= nlstate ; i ++){
                   6527:          if(i==1)
                   6528:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   6529:          else
                   6530:            fprintf(ficgp,", '' ");
                   6531:          /* l=(nlstate+ndeath)*(i-1)+1; */
                   6532:          l=(nlstate+ndeath)*(cpt-1)+1;
                   6533:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   6534:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
                   6535:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+(cpt-1)+i-1); /* a vérifier */
                   6536:          /* for (j=2; j<= nlstate ; j ++) */
                   6537:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   6538:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
                   6539:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",i,cpt);
                   6540:        } /* nlstate */
                   6541:        fprintf(ficgp,"\nset out\n");
1.218     brouard  6542:       } /* end cpt state*/ 
                   6543:     } /* end covariate */  
                   6544:   } /* End if backcast */
                   6545:   
1.223     brouard  6546:   /* 8eme */
1.218     brouard  6547:   if(prevfcast==1){
                   6548:     /* Projection from cross-sectional to stable (period) for each covariate */
                   6549:     
                   6550:     for (k1=1; k1<= m ; k1 ++) { /* For each covariate combination (1 to m=2**k), if any covariate is present */
1.211     brouard  6551:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6552:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   6553:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   6554:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6555:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6556:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6557:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6558:          vlv= nbcode[Tvaraff[k]][lv];
                   6559:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6560:        }
                   6561:        fprintf(ficgp,"\n#\n");
                   6562:        if(invalidvarcomb[k1]){
                   6563:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6564:          continue;
                   6565:        }
                   6566:        
                   6567:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
                   6568:        fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1);
                   6569:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   6570: set ter svg size 640, 480\n                                            \
                   6571: unset log y\n                                                          \
1.219     brouard  6572: plot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  6573:        for (i=1; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   6574:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6575:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   6576:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6577:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   6578:          if(i==1){
                   6579:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   6580:          }else{
                   6581:            fprintf(ficgp,",\\\n '' ");
                   6582:          }
                   6583:          if(cptcoveff ==0){ /* No covariate */
                   6584:            ioffset=2; /* Age is in 2 */
                   6585:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   6586:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   6587:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   6588:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   6589:            fprintf(ficgp," u %d:(", ioffset); 
                   6590:            if(i==nlstate+1)
                   6591:              fprintf(ficgp," $%d/(1.-$%d)) t 'pw.%d' with line ",      \
                   6592:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   6593:            else
                   6594:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   6595:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   6596:          }else{ /* more than 2 covariates */
                   6597:            if(cptcoveff ==1){
                   6598:              ioffset=4; /* Age is in 4 */
                   6599:            }else{
                   6600:              ioffset=6; /* Age is in 6 */
                   6601:              /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6602:              /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   6603:            }   
                   6604:            fprintf(ficgp," u %d:(",ioffset); 
                   6605:            kl=0;
                   6606:            strcpy(gplotcondition,"(");
                   6607:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   6608:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   6609:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6610:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6611:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6612:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   6613:              kl++;
                   6614:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   6615:              kl++;
                   6616:              if(k <cptcoveff && cptcoveff>1)
                   6617:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   6618:            }
                   6619:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   6620:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6621:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6622:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6623:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6624:            if(i==nlstate+1){
                   6625:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p.%d' with line ", gplotcondition, \
                   6626:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   6627:            }else{
                   6628:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   6629:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   6630:            }
                   6631:          } /* end if covariate */
                   6632:        } /* nlstate */
                   6633:        fprintf(ficgp,"\nset out\n");
1.223     brouard  6634:       } /* end cpt state*/
                   6635:     } /* end covariate */
                   6636:   } /* End if prevfcast */
1.227     brouard  6637:   
                   6638:   
1.223     brouard  6639:   /* proba elementaires */
                   6640:   fprintf(ficgp,"\n##############\n#MLE estimated parameters\n#############\n");
1.126     brouard  6641:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  6642:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  6643:     for(k=1; k <=(nlstate+ndeath); k++){
                   6644:       if (k != i) {
1.227     brouard  6645:        fprintf(ficgp,"#   current state %d\n",k);
                   6646:        for(j=1; j <=ncovmodel; j++){
                   6647:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   6648:          jk++; 
                   6649:        }
                   6650:        fprintf(ficgp,"\n");
1.126     brouard  6651:       }
                   6652:     }
1.223     brouard  6653:   }
1.187     brouard  6654:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  6655:   
1.145     brouard  6656:   /*goto avoid;*/
1.200     brouard  6657:   fprintf(ficgp,"\n##############\n#Graphics of probabilities or incidences\n#############\n");
1.187     brouard  6658:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   6659:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   6660:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   6661:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   6662:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   6663:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   6664:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   6665:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   6666:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   6667:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   6668:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   6669:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   6670:   fprintf(ficgp,"#\n");
1.223     brouard  6671:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
                   6672:     fprintf(ficgp,"# ng=%d\n",ng);
1.225     brouard  6673:     fprintf(ficgp,"#   jk=1 to 2^%d=%d\n",cptcoveff,m);
1.223     brouard  6674:     for(jk=1; jk <=m; jk++) {
                   6675:       fprintf(ficgp,"#    jk=%d\n",jk);
                   6676:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng);
                   6677:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   6678:       if (ng==1){
                   6679:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   6680:        fprintf(ficgp,"\nunset log y");
                   6681:       }else if (ng==2){
                   6682:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   6683:        fprintf(ficgp,"\nset log y");
                   6684:       }else if (ng==3){
                   6685:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   6686:        fprintf(ficgp,"\nset log y");
                   6687:       }else
                   6688:        fprintf(ficgp,"\nunset title ");
                   6689:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   6690:       i=1;
                   6691:       for(k2=1; k2<=nlstate; k2++) {
                   6692:        k3=i;
                   6693:        for(k=1; k<=(nlstate+ndeath); k++) {
                   6694:          if (k != k2){
                   6695:            switch( ng) {
                   6696:            case 1:
                   6697:              if(nagesqr==0)
                   6698:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   6699:              else /* nagesqr =1 */
                   6700:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   6701:              break;
                   6702:            case 2: /* ng=2 */
                   6703:              if(nagesqr==0)
                   6704:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   6705:              else /* nagesqr =1 */
                   6706:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   6707:              break;
                   6708:            case 3:
                   6709:              if(nagesqr==0)
                   6710:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   6711:              else /* nagesqr =1 */
                   6712:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   6713:              break;
                   6714:            }
                   6715:            ij=1;/* To be checked else nbcode[0][0] wrong */
                   6716:            for(j=3; j <=ncovmodel-nagesqr; j++) {
                   6717:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
                   6718:              if(ij <=cptcovage) { /* Bug valgrind */
                   6719:                if((j-2)==Tage[ij]) { /* Bug valgrind */
                   6720:                  fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                   6721:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   6722:                  ij++;
                   6723:                }
                   6724:              }
                   6725:              else
1.227     brouard  6726:                fprintf(ficgp,"+p%d*%d",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,j-2)]); /* Valgrind bug nbcode */
1.223     brouard  6727:            }
                   6728:          }else{
                   6729:            i=i-ncovmodel;
                   6730:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   6731:              fprintf(ficgp," (1.");
                   6732:          }
1.227     brouard  6733:          
1.223     brouard  6734:          if(ng != 1){
                   6735:            fprintf(ficgp,")/(1");
1.227     brouard  6736:            
1.223     brouard  6737:            for(k1=1; k1 <=nlstate; k1++){ 
                   6738:              if(nagesqr==0)
                   6739:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                   6740:              else /* nagesqr =1 */
                   6741:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1,k3+(k1-1)*ncovmodel+1+nagesqr);
1.217     brouard  6742:               
1.223     brouard  6743:              ij=1;
                   6744:              for(j=3; j <=ncovmodel-nagesqr; j++){
                   6745:                if(ij <=cptcovage) { /* Bug valgrind */
                   6746:                  if((j-2)==Tage[ij]) { /* Bug valgrind */
                   6747:                    fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                   6748:                    /* fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   6749:                    ij++;
                   6750:                  }
                   6751:                }
                   6752:                else
1.225     brouard  6753:                  fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  6754:              }
                   6755:              fprintf(ficgp,")");
                   6756:            }
                   6757:            fprintf(ficgp,")");
                   6758:            if(ng ==2)
                   6759:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   6760:            else /* ng= 3 */
                   6761:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   6762:          }else{ /* end ng <> 1 */
                   6763:            if( k !=k2) /* logit p11 is hard to draw */
                   6764:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   6765:          }
                   6766:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   6767:            fprintf(ficgp,",");
                   6768:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   6769:            fprintf(ficgp,",");
                   6770:          i=i+ncovmodel;
                   6771:        } /* end k */
                   6772:       } /* end k2 */
                   6773:       fprintf(ficgp,"\n set out\n");
                   6774:     } /* end jk */
                   6775:   } /* end ng */
                   6776:   /* avoid: */
                   6777:   fflush(ficgp); 
1.126     brouard  6778: }  /* end gnuplot */
                   6779: 
                   6780: 
                   6781: /*************** Moving average **************/
1.219     brouard  6782: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  6783:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  6784:    
1.222     brouard  6785:    int i, cpt, cptcod;
                   6786:    int modcovmax =1;
                   6787:    int mobilavrange, mob;
                   6788:    int iage=0;
                   6789: 
                   6790:    double sum=0.;
                   6791:    double age;
                   6792:    double *sumnewp, *sumnewm;
                   6793:    double *agemingood, *agemaxgood; /* Currently identical for all covariates */
                   6794:   
                   6795:   
1.225     brouard  6796:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  6797:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   6798: 
                   6799:    sumnewp = vector(1,ncovcombmax);
                   6800:    sumnewm = vector(1,ncovcombmax);
                   6801:    agemingood = vector(1,ncovcombmax); 
                   6802:    agemaxgood = vector(1,ncovcombmax);
                   6803: 
                   6804:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   6805:      sumnewm[cptcod]=0.;
                   6806:      sumnewp[cptcod]=0.;
                   6807:      agemingood[cptcod]=0;
                   6808:      agemaxgood[cptcod]=0;
                   6809:    }
                   6810:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   6811:   
                   6812:    if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   6813:      if(mobilav==1) mobilavrange=5; /* default */
                   6814:      else mobilavrange=mobilav;
                   6815:      for (age=bage; age<=fage; age++)
                   6816:        for (i=1; i<=nlstate;i++)
                   6817:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   6818:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   6819:      /* We keep the original values on the extreme ages bage, fage and for 
                   6820:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   6821:        we use a 5 terms etc. until the borders are no more concerned. 
                   6822:      */ 
                   6823:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   6824:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
                   6825:         for (i=1; i<=nlstate;i++){
                   6826:           for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   6827:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   6828:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   6829:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   6830:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   6831:             }
                   6832:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
                   6833:           }
                   6834:         }
                   6835:        }/* end age */
                   6836:      }/* end mob */
                   6837:    }else
                   6838:      return -1;
                   6839:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   6840:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   6841:      if(invalidvarcomb[cptcod]){
                   6842:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   6843:        continue;
                   6844:      }
1.219     brouard  6845: 
1.222     brouard  6846:      agemingood[cptcod]=fage-(mob-1)/2;
                   6847:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, finding the youngest wrong */
                   6848:        sumnewm[cptcod]=0.;
                   6849:        for (i=1; i<=nlstate;i++){
                   6850:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   6851:        }
                   6852:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   6853:         agemingood[cptcod]=age;
                   6854:        }else{ /* bad */
                   6855:         for (i=1; i<=nlstate;i++){
                   6856:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   6857:         } /* i */
                   6858:        } /* end bad */
                   6859:      }/* age */
                   6860:      sum=0.;
                   6861:      for (i=1; i<=nlstate;i++){
                   6862:        sum+=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   6863:      }
                   6864:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   6865:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any descending age!\n",cptcod);
                   6866:        /* for (i=1; i<=nlstate;i++){ */
                   6867:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   6868:        /* } /\* i *\/ */
                   6869:      } /* end bad */
                   6870:      /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   6871:      /* From youngest, finding the oldest wrong */
                   6872:      agemaxgood[cptcod]=bage+(mob-1)/2;
                   6873:      for (age=bage+(mob-1)/2; age<=fage; age++){
                   6874:        sumnewm[cptcod]=0.;
                   6875:        for (i=1; i<=nlstate;i++){
                   6876:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   6877:        }
                   6878:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   6879:         agemaxgood[cptcod]=age;
                   6880:        }else{ /* bad */
                   6881:         for (i=1; i<=nlstate;i++){
                   6882:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   6883:         } /* i */
                   6884:        } /* end bad */
                   6885:      }/* age */
                   6886:      sum=0.;
                   6887:      for (i=1; i<=nlstate;i++){
                   6888:        sum+=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   6889:      }
                   6890:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   6891:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any ascending age!\n",cptcod);
                   6892:        /* for (i=1; i<=nlstate;i++){ */
                   6893:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   6894:        /* } /\* i *\/ */
                   6895:      } /* end bad */
                   6896:                
                   6897:      for (age=bage; age<=fage; age++){
                   6898:        printf("%d %d ", cptcod, (int)age);
                   6899:        sumnewp[cptcod]=0.;
                   6900:        sumnewm[cptcod]=0.;
                   6901:        for (i=1; i<=nlstate;i++){
                   6902:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   6903:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   6904:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   6905:        }
                   6906:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   6907:      }
                   6908:      /* printf("\n"); */
                   6909:      /* } */
                   6910:      /* brutal averaging */
                   6911:      for (i=1; i<=nlstate;i++){
                   6912:        for (age=1; age<=bage; age++){
                   6913:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   6914:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   6915:        }       
                   6916:        for (age=fage; age<=AGESUP; age++){
                   6917:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   6918:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   6919:        }
                   6920:      } /* end i status */
                   6921:      for (i=nlstate+1; i<=nlstate+ndeath;i++){
                   6922:        for (age=1; age<=AGESUP; age++){
                   6923:         /*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*/
                   6924:         mobaverage[(int)age][i][cptcod]=0.;
                   6925:        }
                   6926:      }
                   6927:    }/* end cptcod */
                   6928:    free_vector(sumnewm,1, ncovcombmax);
                   6929:    free_vector(sumnewp,1, ncovcombmax);
                   6930:    free_vector(agemaxgood,1, ncovcombmax);
                   6931:    free_vector(agemingood,1, ncovcombmax);
                   6932:    return 0;
                   6933:  }/* End movingaverage */
1.218     brouard  6934:  
1.126     brouard  6935: 
                   6936: /************** Forecasting ******************/
1.225     brouard  6937: void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  6938:   /* proj1, year, month, day of starting projection 
                   6939:      agemin, agemax range of age
                   6940:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   6941:      anproj2 year of en of projection (same day and month as proj1).
                   6942:   */
1.164     brouard  6943:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1;
1.126     brouard  6944:   double agec; /* generic age */
                   6945:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   6946:   double *popeffectif,*popcount;
                   6947:   double ***p3mat;
1.218     brouard  6948:   /* double ***mobaverage; */
1.126     brouard  6949:   char fileresf[FILENAMELENGTH];
                   6950: 
                   6951:   agelim=AGESUP;
1.211     brouard  6952:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   6953:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   6954:      We still use firstpass and lastpass as another selection.
                   6955:   */
1.214     brouard  6956:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   6957:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  6958:  
1.201     brouard  6959:   strcpy(fileresf,"F_"); 
                   6960:   strcat(fileresf,fileresu);
1.126     brouard  6961:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   6962:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   6963:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   6964:   }
1.215     brouard  6965:   printf("Computing forecasting: result on file '%s', please wait... \n", fileresf);
                   6966:   fprintf(ficlog,"Computing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  6967: 
1.225     brouard  6968:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  6969: 
                   6970: 
                   6971:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   6972:   if (stepm<=12) stepsize=1;
                   6973:   if(estepm < stepm){
                   6974:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   6975:   }
                   6976:   else  hstepm=estepm;   
                   6977: 
                   6978:   hstepm=hstepm/stepm; 
                   6979:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   6980:                                fractional in yp1 */
                   6981:   anprojmean=yp;
                   6982:   yp2=modf((yp1*12),&yp);
                   6983:   mprojmean=yp;
                   6984:   yp1=modf((yp2*30.5),&yp);
                   6985:   jprojmean=yp;
                   6986:   if(jprojmean==0) jprojmean=1;
                   6987:   if(mprojmean==0) jprojmean=1;
                   6988: 
1.227     brouard  6989:   i1=pow(2,cptcoveff);
1.126     brouard  6990:   if (cptcovn < 1){i1=1;}
                   6991:   
                   6992:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   6993:   
                   6994:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  6995:   
1.126     brouard  6996: /*           if (h==(int)(YEARM*yearp)){ */
1.227     brouard  6997:   for(k=1;k<=i1;k++){
                   6998:     if(invalidvarcomb[k]){
                   6999:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   7000:       continue;
                   7001:     }
                   7002:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   7003:     for(j=1;j<=cptcoveff;j++) {
                   7004:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7005:     }
                   7006:     fprintf(ficresf," yearproj age");
                   7007:     for(j=1; j<=nlstate+ndeath;j++){ 
                   7008:       for(i=1; i<=nlstate;i++)               
                   7009:        fprintf(ficresf," p%d%d",i,j);
                   7010:       fprintf(ficresf," wp.%d",j);
                   7011:     }
                   7012:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   7013:       fprintf(ficresf,"\n");
                   7014:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
                   7015:       for (agec=fage; agec>=(ageminpar-1); agec--){ 
                   7016:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   7017:        nhstepm = nhstepm/hstepm; 
                   7018:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7019:        oldm=oldms;savm=savms;
                   7020:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k);
                   7021:        
                   7022:        for (h=0; h<=nhstepm; h++){
                   7023:          if (h*hstepm/YEARM*stepm ==yearp) {
                   7024:            fprintf(ficresf,"\n");
                   7025:            for(j=1;j<=cptcoveff;j++) 
                   7026:              fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7027:            fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   7028:          } 
                   7029:          for(j=1; j<=nlstate+ndeath;j++) {
                   7030:            ppij=0.;
                   7031:            for(i=1; i<=nlstate;i++) {
                   7032:              if (mobilav==1) 
                   7033:                ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][k];
                   7034:              else {
                   7035:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   7036:              }
                   7037:              if (h*hstepm/YEARM*stepm== yearp) {
                   7038:                fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   7039:              }
                   7040:            } /* end i */
                   7041:            if (h*hstepm/YEARM*stepm==yearp) {
                   7042:              fprintf(ficresf," %.3f", ppij);
                   7043:            }
                   7044:          }/* end j */
                   7045:        } /* end h */
                   7046:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7047:       } /* end agec */
                   7048:     } /* end yearp */
                   7049:   } /* end  k */
1.219     brouard  7050:        
1.126     brouard  7051:   fclose(ficresf);
1.215     brouard  7052:   printf("End of Computing forecasting \n");
                   7053:   fprintf(ficlog,"End of Computing forecasting\n");
                   7054: 
1.126     brouard  7055: }
                   7056: 
1.218     brouard  7057: /* /\************** Back Forecasting ******************\/ */
1.225     brouard  7058: /* void prevbackforecast(char fileres[], double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
1.218     brouard  7059: /*   /\* back1, year, month, day of starting backection  */
                   7060: /*      agemin, agemax range of age */
                   7061: /*      dateprev1 dateprev2 range of dates during which prevalence is computed */
                   7062: /*      anback2 year of en of backection (same day and month as back1). */
                   7063: /*   *\/ */
                   7064: /*   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1; */
                   7065: /*   double agec; /\* generic age *\/ */
                   7066: /*   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean; */
                   7067: /*   double *popeffectif,*popcount; */
                   7068: /*   double ***p3mat; */
                   7069: /*   /\* double ***mobaverage; *\/ */
                   7070: /*   char fileresfb[FILENAMELENGTH]; */
                   7071:        
                   7072: /*   agelim=AGESUP; */
                   7073: /*   /\* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people */
                   7074: /*      in each health status at the date of interview (if between dateprev1 and dateprev2). */
                   7075: /*      We still use firstpass and lastpass as another selection. */
                   7076: /*   *\/ */
                   7077: /*   /\* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ *\/ */
                   7078: /*   /\*             firstpass, lastpass,  stepm,  weightopt, model); *\/ */
                   7079: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   7080:        
                   7081: /*   strcpy(fileresfb,"FB_");  */
                   7082: /*   strcat(fileresfb,fileresu); */
                   7083: /*   if((ficresfb=fopen(fileresfb,"w"))==NULL) { */
                   7084: /*     printf("Problem with back forecast resultfile: %s\n", fileresfb); */
                   7085: /*     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb); */
                   7086: /*   } */
                   7087: /*   printf("Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7088: /*   fprintf(ficlog,"Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7089:        
1.225     brouard  7090: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.218     brouard  7091:        
                   7092: /*   /\* if (mobilav!=0) { *\/ */
                   7093: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7094: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7095: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7096: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7097: /*   /\*   } *\/ */
                   7098: /*   /\* } *\/ */
                   7099:        
                   7100: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7101: /*   if (stepm<=12) stepsize=1; */
                   7102: /*   if(estepm < stepm){ */
                   7103: /*     printf ("Problem %d lower than %d\n",estepm, stepm); */
                   7104: /*   } */
                   7105: /*   else  hstepm=estepm;    */
                   7106:        
                   7107: /*   hstepm=hstepm/stepm;  */
                   7108: /*   yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   7109: /*                                fractional in yp1 *\/ */
                   7110: /*   anprojmean=yp; */
                   7111: /*   yp2=modf((yp1*12),&yp); */
                   7112: /*   mprojmean=yp; */
                   7113: /*   yp1=modf((yp2*30.5),&yp); */
                   7114: /*   jprojmean=yp; */
                   7115: /*   if(jprojmean==0) jprojmean=1; */
                   7116: /*   if(mprojmean==0) jprojmean=1; */
                   7117:        
1.225     brouard  7118: /*   i1=cptcoveff; */
1.218     brouard  7119: /*   if (cptcovn < 1){i1=1;} */
1.217     brouard  7120:   
1.218     brouard  7121: /*   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);  */
1.217     brouard  7122:   
1.218     brouard  7123: /*   fprintf(ficresfb,"#****** Routine prevbackforecast **\n"); */
                   7124:        
                   7125: /*     /\*           if (h==(int)(YEARM*yearp)){ *\/ */
                   7126: /*   for(cptcov=1, k=0;cptcov<=i1;cptcov++){ */
1.225     brouard  7127: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
1.218     brouard  7128: /*       k=k+1; */
                   7129: /*       fprintf(ficresfb,"\n#****** hbijx=probability over h years, hp.jx is weighted by observed prev \n#"); */
1.225     brouard  7130: /*       for(j=1;j<=cptcoveff;j++) { */
1.218     brouard  7131: /*                             fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7132: /*       } */
                   7133: /*       fprintf(ficresfb," yearbproj age"); */
                   7134: /*       for(j=1; j<=nlstate+ndeath;j++){  */
                   7135: /*                             for(i=1; i<=nlstate;i++)               */
                   7136: /*           fprintf(ficresfb," p%d%d",i,j); */
                   7137: /*                             fprintf(ficresfb," p.%d",j); */
                   7138: /*       } */
                   7139: /*       for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {  */
                   7140: /*                             /\* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  *\/ */
                   7141: /*                             fprintf(ficresfb,"\n"); */
                   7142: /*                             fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);    */
                   7143: /*                             for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   7144: /*                                     nhstepm=(int) rint((agelim-agec)*YEARM/stepm);  */
                   7145: /*                                     nhstepm = nhstepm/hstepm;  */
                   7146: /*                                     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7147: /*                                     oldm=oldms;savm=savms; */
                   7148: /*                                     hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm,oldm,savm, dnewm, doldm, dsavm, k);       */
                   7149: /*                                     for (h=0; h<=nhstepm; h++){ */
                   7150: /*                                             if (h*hstepm/YEARM*stepm ==yearp) { */
                   7151: /*               fprintf(ficresfb,"\n"); */
1.225     brouard  7152: /*               for(j=1;j<=cptcoveff;j++)  */
1.218     brouard  7153: /*                 fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7154: /*                                                     fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec+h*hstepm/YEARM*stepm); */
                   7155: /*                                             }  */
                   7156: /*                                             for(j=1; j<=nlstate+ndeath;j++) { */
                   7157: /*                                                     ppij=0.; */
                   7158: /*                                                     for(i=1; i<=nlstate;i++) { */
                   7159: /*                                                             if (mobilav==1)  */
                   7160: /*                                                                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod]; */
                   7161: /*                                                             else { */
                   7162: /*                                                                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod]; */
                   7163: /*                                                             } */
                   7164: /*                                                             if (h*hstepm/YEARM*stepm== yearp) { */
                   7165: /*                                                                     fprintf(ficresfb," %.3f", p3mat[i][j][h]); */
                   7166: /*                                                             } */
                   7167: /*                                                     } /\* end i *\/ */
                   7168: /*                                                     if (h*hstepm/YEARM*stepm==yearp) { */
                   7169: /*                                                             fprintf(ficresfb," %.3f", ppij); */
                   7170: /*                                                     } */
                   7171: /*                                             }/\* end j *\/ */
                   7172: /*                                     } /\* end h *\/ */
                   7173: /*                                     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7174: /*                             } /\* end agec *\/ */
                   7175: /*       } /\* end yearp *\/ */
                   7176: /*     } /\* end cptcod *\/ */
                   7177: /*   } /\* end  cptcov *\/ */
                   7178:        
                   7179: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7180:        
                   7181: /*   fclose(ficresfb); */
                   7182: /*   printf("End of Computing Back forecasting \n"); */
                   7183: /*   fprintf(ficlog,"End of Computing Back forecasting\n"); */
1.217     brouard  7184:        
1.218     brouard  7185: /* } */
1.217     brouard  7186: 
1.126     brouard  7187: /************** Forecasting *****not tested NB*************/
1.227     brouard  7188: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  7189:   
1.227     brouard  7190: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   7191: /*   int *popage; */
                   7192: /*   double calagedatem, agelim, kk1, kk2; */
                   7193: /*   double *popeffectif,*popcount; */
                   7194: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   7195: /*   /\* double ***mobaverage; *\/ */
                   7196: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  7197: 
1.227     brouard  7198: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7199: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7200: /*   agelim=AGESUP; */
                   7201: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  7202:   
1.227     brouard  7203: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  7204:   
                   7205:   
1.227     brouard  7206: /*   strcpy(filerespop,"POP_");  */
                   7207: /*   strcat(filerespop,fileresu); */
                   7208: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   7209: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   7210: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   7211: /*   } */
                   7212: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   7213: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  7214: 
1.227     brouard  7215: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  7216: 
1.227     brouard  7217: /*   /\* if (mobilav!=0) { *\/ */
                   7218: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7219: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7220: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7221: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7222: /*   /\*   } *\/ */
                   7223: /*   /\* } *\/ */
1.126     brouard  7224: 
1.227     brouard  7225: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7226: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  7227:   
1.227     brouard  7228: /*   agelim=AGESUP; */
1.126     brouard  7229:   
1.227     brouard  7230: /*   hstepm=1; */
                   7231: /*   hstepm=hstepm/stepm;  */
1.218     brouard  7232:        
1.227     brouard  7233: /*   if (popforecast==1) { */
                   7234: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   7235: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   7236: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   7237: /*     }  */
                   7238: /*     popage=ivector(0,AGESUP); */
                   7239: /*     popeffectif=vector(0,AGESUP); */
                   7240: /*     popcount=vector(0,AGESUP); */
1.126     brouard  7241:     
1.227     brouard  7242: /*     i=1;    */
                   7243: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  7244:     
1.227     brouard  7245: /*     imx=i; */
                   7246: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   7247: /*   } */
1.218     brouard  7248:   
1.227     brouard  7249: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   7250: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   7251: /*       k=k+1; */
                   7252: /*       fprintf(ficrespop,"\n#******"); */
                   7253: /*       for(j=1;j<=cptcoveff;j++) { */
                   7254: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7255: /*       } */
                   7256: /*       fprintf(ficrespop,"******\n"); */
                   7257: /*       fprintf(ficrespop,"# Age"); */
                   7258: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   7259: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  7260:       
1.227     brouard  7261: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   7262: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  7263:        
1.227     brouard  7264: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7265: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7266: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7267:          
1.227     brouard  7268: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7269: /*       oldm=oldms;savm=savms; */
                   7270: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  7271:          
1.227     brouard  7272: /*       for (h=0; h<=nhstepm; h++){ */
                   7273: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7274: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7275: /*         }  */
                   7276: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7277: /*           kk1=0.;kk2=0; */
                   7278: /*           for(i=1; i<=nlstate;i++) {               */
                   7279: /*             if (mobilav==1)  */
                   7280: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   7281: /*             else { */
                   7282: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   7283: /*             } */
                   7284: /*           } */
                   7285: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   7286: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   7287: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   7288: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   7289: /*           } */
                   7290: /*         } */
                   7291: /*         for(i=1; i<=nlstate;i++){ */
                   7292: /*           kk1=0.; */
                   7293: /*           for(j=1; j<=nlstate;j++){ */
                   7294: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   7295: /*           } */
                   7296: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   7297: /*         } */
1.218     brouard  7298:            
1.227     brouard  7299: /*         if (h==(int)(calagedatem+12*cpt)) */
                   7300: /*           for(j=1; j<=nlstate;j++)  */
                   7301: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   7302: /*       } */
                   7303: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7304: /*     } */
                   7305: /*       } */
1.218     brouard  7306:       
1.227     brouard  7307: /*       /\******\/ */
1.218     brouard  7308:       
1.227     brouard  7309: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   7310: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   7311: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7312: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7313: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7314:          
1.227     brouard  7315: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7316: /*       oldm=oldms;savm=savms; */
                   7317: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   7318: /*       for (h=0; h<=nhstepm; h++){ */
                   7319: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7320: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7321: /*         }  */
                   7322: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7323: /*           kk1=0.;kk2=0; */
                   7324: /*           for(i=1; i<=nlstate;i++) {               */
                   7325: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   7326: /*           } */
                   7327: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   7328: /*         } */
                   7329: /*       } */
                   7330: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7331: /*     } */
                   7332: /*       } */
                   7333: /*     }  */
                   7334: /*   } */
1.218     brouard  7335:   
1.227     brouard  7336: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  7337:   
1.227     brouard  7338: /*   if (popforecast==1) { */
                   7339: /*     free_ivector(popage,0,AGESUP); */
                   7340: /*     free_vector(popeffectif,0,AGESUP); */
                   7341: /*     free_vector(popcount,0,AGESUP); */
                   7342: /*   } */
                   7343: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7344: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7345: /*   fclose(ficrespop); */
                   7346: /* } /\* End of popforecast *\/ */
1.218     brouard  7347:  
1.126     brouard  7348: int fileappend(FILE *fichier, char *optionfich)
                   7349: {
                   7350:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   7351:     printf("Problem with file: %s\n", optionfich);
                   7352:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   7353:     return (0);
                   7354:   }
                   7355:   fflush(fichier);
                   7356:   return (1);
                   7357: }
                   7358: 
                   7359: 
                   7360: /**************** function prwizard **********************/
                   7361: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   7362: {
                   7363: 
                   7364:   /* Wizard to print covariance matrix template */
                   7365: 
1.164     brouard  7366:   char ca[32], cb[32];
                   7367:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  7368:   int numlinepar;
                   7369: 
                   7370:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7371:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7372:   for(i=1; i <=nlstate; i++){
                   7373:     jj=0;
                   7374:     for(j=1; j <=nlstate+ndeath; j++){
                   7375:       if(j==i) continue;
                   7376:       jj++;
                   7377:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   7378:       printf("%1d%1d",i,j);
                   7379:       fprintf(ficparo,"%1d%1d",i,j);
                   7380:       for(k=1; k<=ncovmodel;k++){
                   7381:        /*        printf(" %lf",param[i][j][k]); */
                   7382:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   7383:        printf(" 0.");
                   7384:        fprintf(ficparo," 0.");
                   7385:       }
                   7386:       printf("\n");
                   7387:       fprintf(ficparo,"\n");
                   7388:     }
                   7389:   }
                   7390:   printf("# Scales (for hessian or gradient estimation)\n");
                   7391:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   7392:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   7393:   for(i=1; i <=nlstate; i++){
                   7394:     jj=0;
                   7395:     for(j=1; j <=nlstate+ndeath; j++){
                   7396:       if(j==i) continue;
                   7397:       jj++;
                   7398:       fprintf(ficparo,"%1d%1d",i,j);
                   7399:       printf("%1d%1d",i,j);
                   7400:       fflush(stdout);
                   7401:       for(k=1; k<=ncovmodel;k++){
                   7402:        /*      printf(" %le",delti3[i][j][k]); */
                   7403:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   7404:        printf(" 0.");
                   7405:        fprintf(ficparo," 0.");
                   7406:       }
                   7407:       numlinepar++;
                   7408:       printf("\n");
                   7409:       fprintf(ficparo,"\n");
                   7410:     }
                   7411:   }
                   7412:   printf("# Covariance matrix\n");
                   7413: /* # 121 Var(a12)\n\ */
                   7414: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7415: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   7416: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   7417: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   7418: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   7419: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   7420: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   7421:   fflush(stdout);
                   7422:   fprintf(ficparo,"# Covariance matrix\n");
                   7423:   /* # 121 Var(a12)\n\ */
                   7424:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7425:   /* #   ...\n\ */
                   7426:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   7427:   
                   7428:   for(itimes=1;itimes<=2;itimes++){
                   7429:     jj=0;
                   7430:     for(i=1; i <=nlstate; i++){
                   7431:       for(j=1; j <=nlstate+ndeath; j++){
                   7432:        if(j==i) continue;
                   7433:        for(k=1; k<=ncovmodel;k++){
                   7434:          jj++;
                   7435:          ca[0]= k+'a'-1;ca[1]='\0';
                   7436:          if(itimes==1){
                   7437:            printf("#%1d%1d%d",i,j,k);
                   7438:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   7439:          }else{
                   7440:            printf("%1d%1d%d",i,j,k);
                   7441:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   7442:            /*  printf(" %.5le",matcov[i][j]); */
                   7443:          }
                   7444:          ll=0;
                   7445:          for(li=1;li <=nlstate; li++){
                   7446:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   7447:              if(lj==li) continue;
                   7448:              for(lk=1;lk<=ncovmodel;lk++){
                   7449:                ll++;
                   7450:                if(ll<=jj){
                   7451:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   7452:                  if(ll<jj){
                   7453:                    if(itimes==1){
                   7454:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7455:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7456:                    }else{
                   7457:                      printf(" 0.");
                   7458:                      fprintf(ficparo," 0.");
                   7459:                    }
                   7460:                  }else{
                   7461:                    if(itimes==1){
                   7462:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   7463:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   7464:                    }else{
                   7465:                      printf(" 0.");
                   7466:                      fprintf(ficparo," 0.");
                   7467:                    }
                   7468:                  }
                   7469:                }
                   7470:              } /* end lk */
                   7471:            } /* end lj */
                   7472:          } /* end li */
                   7473:          printf("\n");
                   7474:          fprintf(ficparo,"\n");
                   7475:          numlinepar++;
                   7476:        } /* end k*/
                   7477:       } /*end j */
                   7478:     } /* end i */
                   7479:   } /* end itimes */
                   7480: 
                   7481: } /* end of prwizard */
                   7482: /******************* Gompertz Likelihood ******************************/
                   7483: double gompertz(double x[])
                   7484: { 
                   7485:   double A,B,L=0.0,sump=0.,num=0.;
                   7486:   int i,n=0; /* n is the size of the sample */
                   7487: 
1.220     brouard  7488:   for (i=1;i<=imx ; i++) {
1.126     brouard  7489:     sump=sump+weight[i];
                   7490:     /*    sump=sump+1;*/
                   7491:     num=num+1;
                   7492:   }
                   7493:  
                   7494:  
                   7495:   /* for (i=0; i<=imx; i++) 
                   7496:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   7497: 
                   7498:   for (i=1;i<=imx ; i++)
                   7499:     {
                   7500:       if (cens[i] == 1 && wav[i]>1)
                   7501:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   7502:       
                   7503:       if (cens[i] == 0 && wav[i]>1)
                   7504:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   7505:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   7506:       
                   7507:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   7508:       if (wav[i] > 1 ) { /* ??? */
                   7509:        L=L+A*weight[i];
                   7510:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   7511:       }
                   7512:     }
                   7513: 
                   7514:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   7515:  
                   7516:   return -2*L*num/sump;
                   7517: }
                   7518: 
1.136     brouard  7519: #ifdef GSL
                   7520: /******************* Gompertz_f Likelihood ******************************/
                   7521: double gompertz_f(const gsl_vector *v, void *params)
                   7522: { 
                   7523:   double A,B,LL=0.0,sump=0.,num=0.;
                   7524:   double *x= (double *) v->data;
                   7525:   int i,n=0; /* n is the size of the sample */
                   7526: 
                   7527:   for (i=0;i<=imx-1 ; i++) {
                   7528:     sump=sump+weight[i];
                   7529:     /*    sump=sump+1;*/
                   7530:     num=num+1;
                   7531:   }
                   7532:  
                   7533:  
                   7534:   /* for (i=0; i<=imx; i++) 
                   7535:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   7536:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   7537:   for (i=1;i<=imx ; i++)
                   7538:     {
                   7539:       if (cens[i] == 1 && wav[i]>1)
                   7540:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   7541:       
                   7542:       if (cens[i] == 0 && wav[i]>1)
                   7543:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   7544:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   7545:       
                   7546:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   7547:       if (wav[i] > 1 ) { /* ??? */
                   7548:        LL=LL+A*weight[i];
                   7549:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   7550:       }
                   7551:     }
                   7552: 
                   7553:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   7554:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   7555:  
                   7556:   return -2*LL*num/sump;
                   7557: }
                   7558: #endif
                   7559: 
1.126     brouard  7560: /******************* Printing html file ***********/
1.201     brouard  7561: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  7562:                  int lastpass, int stepm, int weightopt, char model[],\
                   7563:                  int imx,  double p[],double **matcov,double agemortsup){
                   7564:   int i,k;
                   7565: 
                   7566:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   7567:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   7568:   for (i=1;i<=2;i++) 
                   7569:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  7570:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  7571:   fprintf(fichtm,"</ul>");
                   7572: 
                   7573: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   7574: 
                   7575:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   7576: 
                   7577:  for (k=agegomp;k<(agemortsup-2);k++) 
                   7578:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   7579: 
                   7580:  
                   7581:   fflush(fichtm);
                   7582: }
                   7583: 
                   7584: /******************* Gnuplot file **************/
1.201     brouard  7585: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  7586: 
                   7587:   char dirfileres[132],optfileres[132];
1.164     brouard  7588: 
1.126     brouard  7589:   int ng;
                   7590: 
                   7591: 
                   7592:   /*#ifdef windows */
                   7593:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   7594:     /*#endif */
                   7595: 
                   7596: 
                   7597:   strcpy(dirfileres,optionfilefiname);
                   7598:   strcpy(optfileres,"vpl");
1.199     brouard  7599:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  7600:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  7601:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  7602:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  7603:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   7604: 
                   7605: } 
                   7606: 
1.136     brouard  7607: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   7608: {
1.126     brouard  7609: 
1.136     brouard  7610:   /*-------- data file ----------*/
                   7611:   FILE *fic;
                   7612:   char dummy[]="                         ";
1.223     brouard  7613:   int i=0, j=0, n=0, iv=0;
                   7614:   int lstra;
1.136     brouard  7615:   int linei, month, year,iout;
                   7616:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  7617:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  7618:   char *stratrunc;
1.223     brouard  7619: 
1.126     brouard  7620: 
                   7621: 
1.136     brouard  7622:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  7623:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   7624:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  7625:   }
1.126     brouard  7626: 
1.136     brouard  7627:   i=1;
                   7628:   linei=0;
                   7629:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   7630:     linei=linei+1;
                   7631:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   7632:       if(line[j] == '\t')
                   7633:        line[j] = ' ';
                   7634:     }
                   7635:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   7636:       ;
                   7637:     };
                   7638:     line[j+1]=0;  /* Trims blanks at end of line */
                   7639:     if(line[0]=='#'){
                   7640:       fprintf(ficlog,"Comment line\n%s\n",line);
                   7641:       printf("Comment line\n%s\n",line);
                   7642:       continue;
                   7643:     }
                   7644:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  7645:     strcpy(line, linetmp);
1.223     brouard  7646:     
                   7647:     /* Loops on waves */
                   7648:     for (j=maxwav;j>=1;j--){
                   7649:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.232     brouard  7650:                                cutv(stra, strb, line, ' '); 
                   7651:                                if(strb[0]=='.') { /* Missing value */
                   7652:                                        lval=-1;
                   7653:                                        cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   7654:                                        cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   7655:                                        if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   7656:                                                printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   7657:                                                fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   7658:                                                return 1;
                   7659:                                        }
                   7660:                                }else{
                   7661:                                        errno=0;
                   7662:                                        /* what_kind_of_number(strb); */
                   7663:                                        dval=strtod(strb,&endptr); 
                   7664:                                        /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   7665:                                        /* if(strb != endptr && *endptr == '\0') */
                   7666:                                        /*    dval=dlval; */
                   7667:                                        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   7668:                                        if( strb[0]=='\0' || (*endptr != '\0')){
                   7669:                                                printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   7670:                                                fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   7671:                                                return 1;
                   7672:                                        }
                   7673:                                        cotqvar[j][iv][i]=dval; 
                   7674:                                        cotvar[j][ntv+iv][i]=dval; 
                   7675:                                }
                   7676:                                strcpy(line,stra);
1.223     brouard  7677:       }/* end loop ntqv */
1.225     brouard  7678:       
1.223     brouard  7679:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.232     brouard  7680:                                cutv(stra, strb, line, ' '); 
                   7681:                                if(strb[0]=='.') { /* Missing value */
                   7682:                                        lval=-1;
                   7683:                                }else{
                   7684:                                        errno=0;
                   7685:                                        lval=strtol(strb,&endptr,10); 
                   7686:                                        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   7687:                                        if( strb[0]=='\0' || (*endptr != '\0')){
                   7688:                                                printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   7689:                                                fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   7690:                                                return 1;
                   7691:                                        }
                   7692:                                }
                   7693:                                if(lval <-1 || lval >1){
                   7694:                                        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  7695:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   7696:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.232     brouard  7697:  For example, for multinomial values like 1, 2 and 3,\n                                                                        \
                   7698:  build V1=0 V2=0 for the reference value (1),\n                                                                                                        \
                   7699:         V1=1 V2=0 for (2) \n                                                                                                                                                                           \
1.223     brouard  7700:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.232     brouard  7701:  output of IMaCh is often meaningless.\n                                                                                                                               \
1.223     brouard  7702:  Exiting.\n",lval,linei, i,line,j);
1.232     brouard  7703:                                        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  7704:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   7705:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.232     brouard  7706:  For example, for multinomial values like 1, 2 and 3,\n                                                                        \
                   7707:  build V1=0 V2=0 for the reference value (1),\n                                                                                                        \
                   7708:         V1=1 V2=0 for (2) \n                                                                                                                                                                           \
1.223     brouard  7709:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.232     brouard  7710:  output of IMaCh is often meaningless.\n                                                                                                                               \
1.223     brouard  7711:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.232     brouard  7712:                                        return 1;
                   7713:                                }
                   7714:                                cotvar[j][iv][i]=(double)(lval);
                   7715:                                strcpy(line,stra);
1.223     brouard  7716:       }/* end loop ntv */
1.225     brouard  7717:       
1.223     brouard  7718:       /* Statuses  at wave */
1.137     brouard  7719:       cutv(stra, strb, line, ' '); 
1.223     brouard  7720:       if(strb[0]=='.') { /* Missing value */
1.232     brouard  7721:                                lval=-1;
1.136     brouard  7722:       }else{
1.232     brouard  7723:                                errno=0;
                   7724:                                lval=strtol(strb,&endptr,10); 
                   7725:                                /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   7726:                                if( strb[0]=='\0' || (*endptr != '\0')){
                   7727:                                        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   7728:                                        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   7729:                                        return 1;
                   7730:                                }
1.136     brouard  7731:       }
1.225     brouard  7732:       
1.136     brouard  7733:       s[j][i]=lval;
1.225     brouard  7734:       
1.223     brouard  7735:       /* Date of Interview */
1.136     brouard  7736:       strcpy(line,stra);
                   7737:       cutv(stra, strb,line,' ');
1.169     brouard  7738:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  7739:       }
1.169     brouard  7740:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  7741:        month=99;
                   7742:        year=9999;
1.136     brouard  7743:       }else{
1.225     brouard  7744:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   7745:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   7746:        return 1;
1.136     brouard  7747:       }
                   7748:       anint[j][i]= (double) year; 
                   7749:       mint[j][i]= (double)month; 
                   7750:       strcpy(line,stra);
1.223     brouard  7751:     } /* End loop on waves */
1.225     brouard  7752:     
1.223     brouard  7753:     /* Date of death */
1.136     brouard  7754:     cutv(stra, strb,line,' '); 
1.169     brouard  7755:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  7756:     }
1.169     brouard  7757:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  7758:       month=99;
                   7759:       year=9999;
                   7760:     }else{
1.141     brouard  7761:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  7762:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   7763:       return 1;
1.136     brouard  7764:     }
                   7765:     andc[i]=(double) year; 
                   7766:     moisdc[i]=(double) month; 
                   7767:     strcpy(line,stra);
                   7768:     
1.223     brouard  7769:     /* Date of birth */
1.136     brouard  7770:     cutv(stra, strb,line,' '); 
1.169     brouard  7771:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  7772:     }
1.169     brouard  7773:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  7774:       month=99;
                   7775:       year=9999;
                   7776:     }else{
1.141     brouard  7777:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   7778:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  7779:       return 1;
1.136     brouard  7780:     }
                   7781:     if (year==9999) {
1.141     brouard  7782:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   7783:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  7784:       return 1;
                   7785:       
1.136     brouard  7786:     }
                   7787:     annais[i]=(double)(year);
                   7788:     moisnais[i]=(double)(month); 
                   7789:     strcpy(line,stra);
1.225     brouard  7790:     
1.223     brouard  7791:     /* Sample weight */
1.136     brouard  7792:     cutv(stra, strb,line,' '); 
                   7793:     errno=0;
                   7794:     dval=strtod(strb,&endptr); 
                   7795:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  7796:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   7797:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  7798:       fflush(ficlog);
                   7799:       return 1;
                   7800:     }
                   7801:     weight[i]=dval; 
                   7802:     strcpy(line,stra);
1.225     brouard  7803:     
1.223     brouard  7804:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   7805:       cutv(stra, strb, line, ' '); 
                   7806:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  7807:        lval=-1;
1.223     brouard  7808:       }else{
1.225     brouard  7809:        errno=0;
                   7810:        /* what_kind_of_number(strb); */
                   7811:        dval=strtod(strb,&endptr);
                   7812:        /* if(strb != endptr && *endptr == '\0') */
                   7813:        /*   dval=dlval; */
                   7814:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   7815:        if( strb[0]=='\0' || (*endptr != '\0')){
                   7816:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   7817:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   7818:          return 1;
                   7819:        }
                   7820:        coqvar[iv][i]=dval; 
1.226     brouard  7821:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  7822:       }
                   7823:       strcpy(line,stra);
                   7824:     }/* end loop nqv */
1.136     brouard  7825:     
1.223     brouard  7826:     /* Covariate values */
1.136     brouard  7827:     for (j=ncovcol;j>=1;j--){
                   7828:       cutv(stra, strb,line,' '); 
1.223     brouard  7829:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  7830:        lval=-1;
1.136     brouard  7831:       }else{
1.225     brouard  7832:        errno=0;
                   7833:        lval=strtol(strb,&endptr,10); 
                   7834:        if( strb[0]=='\0' || (*endptr != '\0')){
                   7835:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   7836:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   7837:          return 1;
                   7838:        }
1.136     brouard  7839:       }
                   7840:       if(lval <-1 || lval >1){
1.225     brouard  7841:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  7842:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   7843:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  7844:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   7845:  build V1=0 V2=0 for the reference value (1),\n                                \
                   7846:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  7847:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  7848:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  7849:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  7850:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  7851:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   7852:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  7853:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   7854:  build V1=0 V2=0 for the reference value (1),\n                                \
                   7855:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  7856:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  7857:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  7858:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  7859:        return 1;
1.136     brouard  7860:       }
                   7861:       covar[j][i]=(double)(lval);
                   7862:       strcpy(line,stra);
                   7863:     }  
                   7864:     lstra=strlen(stra);
1.225     brouard  7865:     
1.136     brouard  7866:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   7867:       stratrunc = &(stra[lstra-9]);
                   7868:       num[i]=atol(stratrunc);
                   7869:     }
                   7870:     else
                   7871:       num[i]=atol(stra);
                   7872:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   7873:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   7874:     
                   7875:     i=i+1;
                   7876:   } /* End loop reading  data */
1.225     brouard  7877:   
1.136     brouard  7878:   *imax=i-1; /* Number of individuals */
                   7879:   fclose(fic);
1.225     brouard  7880:   
1.136     brouard  7881:   return (0);
1.164     brouard  7882:   /* endread: */
1.225     brouard  7883:   printf("Exiting readdata: ");
                   7884:   fclose(fic);
                   7885:   return (1);
1.223     brouard  7886: }
1.126     brouard  7887: 
1.234   ! brouard  7888: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  7889:   char *p1 = *stri, *p2 = *stri;
1.234   ! brouard  7890:   if (*p2 == ' ')
        !          7891:     p2++; 
        !          7892:   /* while ((*p1++ = *p2++) !=0) */
        !          7893:   /*   ; */
        !          7894:   /* do */
        !          7895:   /*   while (*p2 == ' ') */
        !          7896:   /*     p2++; */
        !          7897:   /* while (*p1++ == *p2++); */
        !          7898:   *stri=p2; 
1.145     brouard  7899: }
                   7900: 
1.230     brouard  7901: int decoderesult ( char resultline[])
                   7902: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   7903: {
1.234   ! brouard  7904:   int j=0, k=0, k1=0, k2=0, match=0;
1.230     brouard  7905:   char resultsav[MAXLINE];
1.234   ! brouard  7906:   int resultmodel[MAXLINE];
        !          7907:   int modelresult[MAXLINE];
1.230     brouard  7908:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   7909: 
1.234   ! brouard  7910:   removefirstspace(&resultline);
1.233     brouard  7911:   printf("decoderesult:%s\n",resultline);
1.230     brouard  7912: 
                   7913:   if (strstr(resultline,"v") !=0){
                   7914:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   7915:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   7916:     return 1;
                   7917:   }
                   7918:   trimbb(resultsav, resultline);
                   7919:   if (strlen(resultsav) >1){
                   7920:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   7921:   }
1.234   ! brouard  7922:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
        !          7923:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
        !          7924:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
        !          7925:   }
        !          7926:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
        !          7927:     if(nbocc(resultsav,'=') >1){
        !          7928:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
        !          7929:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
        !          7930:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
        !          7931:     }else
        !          7932:       cutl(strc,strd,resultsav,'=');
1.230     brouard  7933:     Tvalsel[k]=atof(strc); /* 1 */
1.234   ! brouard  7934:     
1.230     brouard  7935:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   7936:     Tvarsel[k]=atoi(strc);
                   7937:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   7938:     /* cptcovsel++;     */
                   7939:     if (nbocc(stra,'=') >0)
                   7940:       strcpy(resultsav,stra); /* and analyzes it */
                   7941:   }
1.234   ! brouard  7942:   /* Checking if no missing or useless values in comparison of current model needs */
        !          7943:   for(k1=1; k1<= cptcovt ;k1++){ /* model line */
        !          7944:     if(Typevar[k1]==0){
        !          7945:       match=0;
        !          7946:       for(k2=1; k2 <=j;k2++){
        !          7947:        if(Tvar[k1]==Tvarsel[k2]) {
        !          7948:          modelresult[k2]=k1;
        !          7949:          match=1;
        !          7950:          break;
        !          7951:        }
        !          7952:       }
        !          7953:       if(match == 0){
        !          7954:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
        !          7955:       }
        !          7956:     }
        !          7957:   }
        !          7958:   
        !          7959:   for(k2=1; k2 <=j;k2++){ /* result line */
        !          7960:     match=0;
        !          7961:     for(k1=1; k1<= cptcovt ;k1++){ /* model line */
        !          7962:       if(Typevar[k1]==0){
        !          7963:        if(Tvar[k1]==Tvarsel[k2]) {
        !          7964:          resultmodel[k1]=k2;
        !          7965:          ++match;
        !          7966:        }
        !          7967:       }
        !          7968:     }
        !          7969:     if(match == 0){
        !          7970:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
        !          7971:     }else if(match > 1){
        !          7972:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
        !          7973:     }
        !          7974:   }
        !          7975:   
        !          7976:   /* We need to deduce which combination number is chosen and save quantitative values */
        !          7977:   
1.230     brouard  7978:   return (0);
                   7979: }
                   7980: int selected( int kvar){ /* Selected combination of covariates */
                   7981:   if(Tvarsel[kvar])
                   7982:     return (0);
                   7983:   else
                   7984:     return(1);
                   7985: }
                   7986: int decodemodel( char model[], int lastobs)
                   7987:  /**< This routine decodes the model and returns:
1.224     brouard  7988:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   7989:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   7990:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   7991:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   7992:        * - cptcovage number of covariates with age*products =2
                   7993:        * - cptcovs number of simple covariates
                   7994:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   7995:        *     which is a new column after the 9 (ncovcol) variables. 
                   7996:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   7997:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   7998:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   7999:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   8000:        */
1.136     brouard  8001: {
1.145     brouard  8002:   int i, j, k, ks;
1.227     brouard  8003:   int  j1, k1, k2, k3, k4;
1.136     brouard  8004:   char modelsav[80];
1.145     brouard  8005:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  8006:   char *strpt;
1.136     brouard  8007: 
1.145     brouard  8008:   /*removespace(model);*/
1.136     brouard  8009:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  8010:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  8011:     if (strstr(model,"AGE") !=0){
1.192     brouard  8012:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   8013:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  8014:       return 1;
                   8015:     }
1.141     brouard  8016:     if (strstr(model,"v") !=0){
                   8017:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   8018:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   8019:       return 1;
                   8020:     }
1.187     brouard  8021:     strcpy(modelsav,model); 
                   8022:     if ((strpt=strstr(model,"age*age")) !=0){
                   8023:       printf(" strpt=%s, model=%s\n",strpt, model);
                   8024:       if(strpt != model){
1.234   ! brouard  8025:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8026:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8027:  corresponding column of parameters.\n",model);
1.234   ! brouard  8028:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8029:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8030:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234   ! brouard  8031:        return 1;
1.225     brouard  8032:       }
1.187     brouard  8033:       nagesqr=1;
                   8034:       if (strstr(model,"+age*age") !=0)
1.234   ! brouard  8035:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  8036:       else if (strstr(model,"age*age+") !=0)
1.234   ! brouard  8037:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  8038:       else 
1.234   ! brouard  8039:        substrchaine(modelsav, model, "age*age");
1.187     brouard  8040:     }else
                   8041:       nagesqr=0;
                   8042:     if (strlen(modelsav) >1){
                   8043:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   8044:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  8045:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  8046:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  8047:                     * cst, age and age*age 
                   8048:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   8049:       /* including age products which are counted in cptcovage.
                   8050:        * but the covariates which are products must be treated 
                   8051:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  8052:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   8053:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  8054:       
                   8055:       
1.187     brouard  8056:       /*   Design
                   8057:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   8058:        *  <          ncovcol=8                >
                   8059:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   8060:        *   k=  1    2      3       4     5       6      7        8
                   8061:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   8062:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  8063:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   8064:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  8065:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   8066:        *  Tage[++cptcovage]=k
                   8067:        *       if products, new covar are created after ncovcol with k1
                   8068:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   8069:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   8070:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   8071:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   8072:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   8073:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   8074:        *  <          ncovcol=8                >
                   8075:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   8076:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   8077:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   8078:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8079:        * p Tprod[1]@2={                         6, 5}
                   8080:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   8081:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   8082:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   8083:        *How to reorganize?
                   8084:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   8085:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8086:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   8087:        * Struct []
                   8088:        */
1.225     brouard  8089:       
1.187     brouard  8090:       /* This loop fills the array Tvar from the string 'model'.*/
                   8091:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   8092:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   8093:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   8094:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   8095:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   8096:       /*       k=1 Tvar[1]=2 (from V2) */
                   8097:       /*       k=5 Tvar[5] */
                   8098:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  8099:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  8100:       /*       } */
1.198     brouard  8101:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  8102:       /*
                   8103:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  8104:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   8105:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   8106:       }
1.187     brouard  8107:       cptcovage=0;
                   8108:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234   ! brouard  8109:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  8110:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234   ! brouard  8111:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
        !          8112:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
        !          8113:        /*scanf("%d",i);*/
        !          8114:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
        !          8115:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
        !          8116:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
        !          8117:            /* covar is not filled and then is empty */
        !          8118:            cptcovprod--;
        !          8119:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
        !          8120:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
        !          8121:            Typevar[k]=1;  /* 1 for age product */
        !          8122:            cptcovage++; /* Sums the number of covariates which include age as a product */
        !          8123:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
        !          8124:            /*printf("stre=%s ", stre);*/
        !          8125:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
        !          8126:            cptcovprod--;
        !          8127:            cutl(stre,strb,strc,'V');
        !          8128:            Tvar[k]=atoi(stre);
        !          8129:            Typevar[k]=1;  /* 1 for age product */
        !          8130:            cptcovage++;
        !          8131:            Tage[cptcovage]=k;
        !          8132:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
        !          8133:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
        !          8134:            cptcovn++;
        !          8135:            cptcovprodnoage++;k1++;
        !          8136:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
        !          8137:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
        !          8138:                                                because this model-covariate is a construction we invent a new column
        !          8139:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
        !          8140:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
        !          8141:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
        !          8142:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
        !          8143:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
        !          8144:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
        !          8145:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
        !          8146:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
        !          8147:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
        !          8148:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
        !          8149:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
        !          8150:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  8151:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234   ! brouard  8152:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
        !          8153:            for (i=1; i<=lastobs;i++){
        !          8154:              /* Computes the new covariate which is a product of
        !          8155:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
        !          8156:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
        !          8157:            }
        !          8158:          } /* End age is not in the model */
        !          8159:        } /* End if model includes a product */
        !          8160:        else { /* no more sum */
        !          8161:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
        !          8162:          /*  scanf("%d",i);*/
        !          8163:          cutl(strd,strc,strb,'V');
        !          8164:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
        !          8165:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
        !          8166:          Tvar[k]=atoi(strd);
        !          8167:          Typevar[k]=0;  /* 0 for simple covariates */
        !          8168:        }
        !          8169:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  8170:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  8171:                                  scanf("%d",i);*/
1.187     brouard  8172:       } /* end of loop + on total covariates */
                   8173:     } /* end if strlen(modelsave == 0) age*age might exist */
                   8174:   } /* end if strlen(model == 0) */
1.136     brouard  8175:   
                   8176:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   8177:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  8178:   
1.136     brouard  8179:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  8180:      printf("cptcovprod=%d ", cptcovprod);
                   8181:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   8182:      scanf("%d ",i);*/
                   8183: 
                   8184: 
1.230     brouard  8185: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   8186:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  8187: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   8188:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   8189:    k =           1    2   3     4       5       6      7      8        9
                   8190:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   8191:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  8192:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   8193:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   8194:          Tmodelind[combination of covar]=k;
1.225     brouard  8195: */  
                   8196: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  8197:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  8198:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  8199:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  8200:   printf("Model=%s\n\
                   8201: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8202: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8203: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8204:   fprintf(ficlog,"Model=%s\n\
                   8205: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8206: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8207: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8208: 
1.234   ! brouard  8209:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
        !          8210:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  8211:       Fixed[k]= 0;
                   8212:       Dummy[k]= 0;
1.225     brouard  8213:       ncoveff++;
1.232     brouard  8214:       ncovf++;
1.234   ! brouard  8215:       nsd++;
        !          8216:       modell[k].maintype= FTYPE;
        !          8217:       TvarsD[nsd]=Tvar[k];
        !          8218:       TvarsDind[nsd]=k;
        !          8219:       TvarF[ncovf]=Tvar[k];
        !          8220:       TvarFind[ncovf]=k;
        !          8221:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
        !          8222:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
        !          8223:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
        !          8224:       Fixed[k]= 0;
        !          8225:       Dummy[k]= 0;
        !          8226:       ncoveff++;
        !          8227:       ncovf++;
        !          8228:       modell[k].maintype= FTYPE;
        !          8229:       TvarF[ncovf]=Tvar[k];
        !          8230:       TvarFind[ncovf]=k;
1.230     brouard  8231:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  8232:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8233:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){ /* Remind that product Vn*Vm are added in k*/ /* Only simple fixed quantitative variable */
1.227     brouard  8234:       Fixed[k]= 0;
                   8235:       Dummy[k]= 1;
1.230     brouard  8236:       nqfveff++;
1.234   ! brouard  8237:       modell[k].maintype= FTYPE;
        !          8238:       modell[k].subtype= FQ;
        !          8239:       nsq++;
        !          8240:       TvarsQ[nsq]=Tvar[k];
        !          8241:       TvarsQind[nsq]=k;
1.232     brouard  8242:       ncovf++;
1.234   ! brouard  8243:       TvarF[ncovf]=Tvar[k];
        !          8244:       TvarFind[ncovf]=k;
1.231     brouard  8245:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  8246:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.234   ! brouard  8247:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying variables */
1.227     brouard  8248:       Fixed[k]= 1;
                   8249:       Dummy[k]= 0;
1.225     brouard  8250:       ntveff++; /* Only simple time varying dummy variable */
1.234   ! brouard  8251:       modell[k].maintype= VTYPE;
        !          8252:       modell[k].subtype= VD;
        !          8253:       nsd++;
        !          8254:       TvarsD[nsd]=Tvar[k];
        !          8255:       TvarsDind[nsd]=k;
        !          8256:       ncovv++; /* Only simple time varying variables */
        !          8257:       TvarV[ncovv]=Tvar[k];
        !          8258:       TvarVind[ncovv]=k;
1.231     brouard  8259:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   8260:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  8261:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   8262:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  8263:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234   ! brouard  8264:       Fixed[k]= 1;
        !          8265:       Dummy[k]= 1;
        !          8266:       nqtveff++;
        !          8267:       modell[k].maintype= VTYPE;
        !          8268:       modell[k].subtype= VQ;
        !          8269:       ncovv++; /* Only simple time varying variables */
        !          8270:       nsq++;
        !          8271:       TvarsQ[nsq]=Tvar[k];
        !          8272:       TvarsQind[nsq]=k;
        !          8273:       TvarV[ncovv]=Tvar[k];
        !          8274:       TvarVind[ncovv]=k;
1.231     brouard  8275:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   8276:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234   ! brouard  8277:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
        !          8278:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
        !          8279:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  8280:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  8281:     }else if (Typevar[k] == 1) {  /* product with age */
1.234   ! brouard  8282:       ncova++;
        !          8283:       TvarA[ncova]=Tvar[k];
        !          8284:       TvarAind[ncova]=k;
1.231     brouard  8285:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.234   ! brouard  8286:        Fixed[k]= 2;
        !          8287:        Dummy[k]= 2;
        !          8288:        modell[k].maintype= ATYPE;
        !          8289:        modell[k].subtype= APFD;
        !          8290:        /* ncoveff++; */
1.227     brouard  8291:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.234   ! brouard  8292:        Fixed[k]= 2;
        !          8293:        Dummy[k]= 3;
        !          8294:        modell[k].maintype= ATYPE;
        !          8295:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
        !          8296:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  8297:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.234   ! brouard  8298:        Fixed[k]= 3;
        !          8299:        Dummy[k]= 2;
        !          8300:        modell[k].maintype= ATYPE;
        !          8301:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
        !          8302:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  8303:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.234   ! brouard  8304:        Fixed[k]= 3;
        !          8305:        Dummy[k]= 3;
        !          8306:        modell[k].maintype= ATYPE;
        !          8307:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
        !          8308:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  8309:       }
                   8310:     }else if (Typevar[k] == 2) {  /* product without age */
                   8311:       k1=Tposprod[k];
                   8312:       if(Tvard[k1][1] <=ncovcol){
1.234   ! brouard  8313:        if(Tvard[k1][2] <=ncovcol){
        !          8314:          Fixed[k]= 1;
        !          8315:          Dummy[k]= 0;
        !          8316:          modell[k].maintype= FTYPE;
        !          8317:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
        !          8318:          ncovf++; /* Fixed variables without age */
        !          8319:          TvarF[ncovf]=Tvar[k];
        !          8320:          TvarFind[ncovf]=k;
        !          8321:        }else if(Tvard[k1][2] <=ncovcol+nqv){
        !          8322:          Fixed[k]= 0;  /* or 2 ?*/
        !          8323:          Dummy[k]= 1;
        !          8324:          modell[k].maintype= FTYPE;
        !          8325:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
        !          8326:          ncovf++; /* Varying variables without age */
        !          8327:          TvarF[ncovf]=Tvar[k];
        !          8328:          TvarFind[ncovf]=k;
        !          8329:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
        !          8330:          Fixed[k]= 1;
        !          8331:          Dummy[k]= 0;
        !          8332:          modell[k].maintype= VTYPE;
        !          8333:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
        !          8334:          ncovv++; /* Varying variables without age */
        !          8335:          TvarV[ncovv]=Tvar[k];
        !          8336:          TvarVind[ncovv]=k;
        !          8337:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
        !          8338:          Fixed[k]= 1;
        !          8339:          Dummy[k]= 1;
        !          8340:          modell[k].maintype= VTYPE;
        !          8341:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
        !          8342:          ncovv++; /* Varying variables without age */
        !          8343:          TvarV[ncovv]=Tvar[k];
        !          8344:          TvarVind[ncovv]=k;
        !          8345:        } 
1.227     brouard  8346:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.234   ! brouard  8347:        if(Tvard[k1][2] <=ncovcol){
        !          8348:          Fixed[k]= 0;  /* or 2 ?*/
        !          8349:          Dummy[k]= 1;
        !          8350:          modell[k].maintype= FTYPE;
        !          8351:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
        !          8352:          ncovf++; /* Fixed variables without age */
        !          8353:          TvarF[ncovf]=Tvar[k];
        !          8354:          TvarFind[ncovf]=k;
        !          8355:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
        !          8356:          Fixed[k]= 1;
        !          8357:          Dummy[k]= 1;
        !          8358:          modell[k].maintype= VTYPE;
        !          8359:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
        !          8360:          ncovv++; /* Varying variables without age */
        !          8361:          TvarV[ncovv]=Tvar[k];
        !          8362:          TvarVind[ncovv]=k;
        !          8363:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
        !          8364:          Fixed[k]= 1;
        !          8365:          Dummy[k]= 1;
        !          8366:          modell[k].maintype= VTYPE;
        !          8367:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
        !          8368:          ncovv++; /* Varying variables without age */
        !          8369:          TvarV[ncovv]=Tvar[k];
        !          8370:          TvarVind[ncovv]=k;
        !          8371:          ncovv++; /* Varying variables without age */
        !          8372:          TvarV[ncovv]=Tvar[k];
        !          8373:          TvarVind[ncovv]=k;
        !          8374:        } 
1.227     brouard  8375:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.234   ! brouard  8376:        if(Tvard[k1][2] <=ncovcol){
        !          8377:          Fixed[k]= 1;
        !          8378:          Dummy[k]= 1;
        !          8379:          modell[k].maintype= VTYPE;
        !          8380:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
        !          8381:          ncovv++; /* Varying variables without age */
        !          8382:          TvarV[ncovv]=Tvar[k];
        !          8383:          TvarVind[ncovv]=k;
        !          8384:        }else if(Tvard[k1][2] <=ncovcol+nqv){
        !          8385:          Fixed[k]= 1;
        !          8386:          Dummy[k]= 1;
        !          8387:          modell[k].maintype= VTYPE;
        !          8388:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
        !          8389:          ncovv++; /* Varying variables without age */
        !          8390:          TvarV[ncovv]=Tvar[k];
        !          8391:          TvarVind[ncovv]=k;
        !          8392:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
        !          8393:          Fixed[k]= 1;
        !          8394:          Dummy[k]= 0;
        !          8395:          modell[k].maintype= VTYPE;
        !          8396:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
        !          8397:          ncovv++; /* Varying variables without age */
        !          8398:          TvarV[ncovv]=Tvar[k];
        !          8399:          TvarVind[ncovv]=k;
        !          8400:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
        !          8401:          Fixed[k]= 1;
        !          8402:          Dummy[k]= 1;
        !          8403:          modell[k].maintype= VTYPE;
        !          8404:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
        !          8405:          ncovv++; /* Varying variables without age */
        !          8406:          TvarV[ncovv]=Tvar[k];
        !          8407:          TvarVind[ncovv]=k;
        !          8408:        } 
1.227     brouard  8409:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.234   ! brouard  8410:        if(Tvard[k1][2] <=ncovcol){
        !          8411:          Fixed[k]= 1;
        !          8412:          Dummy[k]= 1;
        !          8413:          modell[k].maintype= VTYPE;
        !          8414:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
        !          8415:          ncovv++; /* Varying variables without age */
        !          8416:          TvarV[ncovv]=Tvar[k];
        !          8417:          TvarVind[ncovv]=k;
        !          8418:        }else if(Tvard[k1][2] <=ncovcol+nqv){
        !          8419:          Fixed[k]= 1;
        !          8420:          Dummy[k]= 1;
        !          8421:          modell[k].maintype= VTYPE;
        !          8422:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
        !          8423:          ncovv++; /* Varying variables without age */
        !          8424:          TvarV[ncovv]=Tvar[k];
        !          8425:          TvarVind[ncovv]=k;
        !          8426:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
        !          8427:          Fixed[k]= 1;
        !          8428:          Dummy[k]= 1;
        !          8429:          modell[k].maintype= VTYPE;
        !          8430:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
        !          8431:          ncovv++; /* Varying variables without age */
        !          8432:          TvarV[ncovv]=Tvar[k];
        !          8433:          TvarVind[ncovv]=k;
        !          8434:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
        !          8435:          Fixed[k]= 1;
        !          8436:          Dummy[k]= 1;
        !          8437:          modell[k].maintype= VTYPE;
        !          8438:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
        !          8439:          ncovv++; /* Varying variables without age */
        !          8440:          TvarV[ncovv]=Tvar[k];
        !          8441:          TvarVind[ncovv]=k;
        !          8442:        } 
1.227     brouard  8443:       }else{
1.234   ! brouard  8444:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
        !          8445:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
1.226     brouard  8446:       } /* end k1 */
1.225     brouard  8447:     }else{
1.226     brouard  8448:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   8449:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  8450:     }
1.227     brouard  8451:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  8452:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  8453:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   8454:   }
                   8455:   /* Searching for doublons in the model */
                   8456:   for(k1=1; k1<= cptcovt;k1++){
                   8457:     for(k2=1; k2 <k1;k2++){
                   8458:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234   ! brouard  8459:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
        !          8460:          if(Tvar[k1]==Tvar[k2]){
        !          8461:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
        !          8462:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
        !          8463:            return(1);
        !          8464:          }
        !          8465:        }else if (Typevar[k1] ==2){
        !          8466:          k3=Tposprod[k1];
        !          8467:          k4=Tposprod[k2];
        !          8468:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
        !          8469:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
        !          8470:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
        !          8471:            return(1);
        !          8472:          }
        !          8473:        }
1.227     brouard  8474:       }
                   8475:     }
1.225     brouard  8476:   }
                   8477:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   8478:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234   ! brouard  8479:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
        !          8480:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  8481:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  8482:   /*endread:*/
1.225     brouard  8483:   printf("Exiting decodemodel: ");
                   8484:   return (1);
1.136     brouard  8485: }
                   8486: 
1.169     brouard  8487: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.136     brouard  8488: {
                   8489:   int i, m;
1.218     brouard  8490:   int firstone=0;
                   8491:   
1.136     brouard  8492:   for (i=1; i<=imx; i++) {
                   8493:     for(m=2; (m<= maxwav); m++) {
                   8494:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   8495:        anint[m][i]=9999;
1.216     brouard  8496:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   8497:          s[m][i]=-1;
1.136     brouard  8498:       }
                   8499:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.169     brouard  8500:        *nberr = *nberr + 1;
1.218     brouard  8501:        if(firstone == 0){
                   8502:          firstone=1;
                   8503:        printf("Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\nOther similar cases in log file\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
                   8504:        }
                   8505:        fprintf(ficlog,"Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
1.136     brouard  8506:        s[m][i]=-1;
                   8507:       }
                   8508:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  8509:        (*nberr)++;
1.136     brouard  8510:        printf("Error! Month of death of individual %ld on line %d was unknown %2d, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,(int)moisdc[i]); 
                   8511:        fprintf(ficlog,"Error! Month of death of individual %ld on line %d was unknown %f, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,moisdc[i]); 
                   8512:        s[m][i]=-1; /* We prefer to skip it (and to skip it in version 0.8a1 too */
                   8513:       }
                   8514:     }
                   8515:   }
                   8516: 
                   8517:   for (i=1; i<=imx; i++)  {
                   8518:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   8519:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  8520:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  8521:        if (s[m][i] >= nlstate+1) {
1.169     brouard  8522:          if(agedc[i]>0){
                   8523:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  8524:              agev[m][i]=agedc[i];
1.214     brouard  8525:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  8526:            }else {
1.136     brouard  8527:              if ((int)andc[i]!=9999){
                   8528:                nbwarn++;
                   8529:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   8530:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   8531:                agev[m][i]=-1;
                   8532:              }
                   8533:            }
1.169     brouard  8534:          } /* agedc > 0 */
1.214     brouard  8535:        } /* end if */
1.136     brouard  8536:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   8537:                                 years but with the precision of a month */
                   8538:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   8539:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   8540:            agev[m][i]=1;
                   8541:          else if(agev[m][i] < *agemin){ 
                   8542:            *agemin=agev[m][i];
                   8543:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   8544:          }
                   8545:          else if(agev[m][i] >*agemax){
                   8546:            *agemax=agev[m][i];
1.156     brouard  8547:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  8548:          }
                   8549:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   8550:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  8551:        } /* en if 9*/
1.136     brouard  8552:        else { /* =9 */
1.214     brouard  8553:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  8554:          agev[m][i]=1;
                   8555:          s[m][i]=-1;
                   8556:        }
                   8557:       }
1.214     brouard  8558:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  8559:        agev[m][i]=1;
1.214     brouard  8560:       else{
                   8561:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   8562:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   8563:        agev[m][i]=0;
                   8564:       }
                   8565:     } /* End for lastpass */
                   8566:   }
1.136     brouard  8567:     
                   8568:   for (i=1; i<=imx; i++)  {
                   8569:     for(m=firstpass; (m<=lastpass); m++){
                   8570:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  8571:        (*nberr)++;
1.136     brouard  8572:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   8573:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   8574:        return 1;
                   8575:       }
                   8576:     }
                   8577:   }
                   8578: 
                   8579:   /*for (i=1; i<=imx; i++){
                   8580:   for (m=firstpass; (m<lastpass); m++){
                   8581:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   8582: }
                   8583: 
                   8584: }*/
                   8585: 
                   8586: 
1.139     brouard  8587:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   8588:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  8589: 
                   8590:   return (0);
1.164     brouard  8591:  /* endread:*/
1.136     brouard  8592:     printf("Exiting calandcheckages: ");
                   8593:     return (1);
                   8594: }
                   8595: 
1.172     brouard  8596: #if defined(_MSC_VER)
                   8597: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   8598: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   8599: //#include "stdafx.h"
                   8600: //#include <stdio.h>
                   8601: //#include <tchar.h>
                   8602: //#include <windows.h>
                   8603: //#include <iostream>
                   8604: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   8605: 
                   8606: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   8607: 
                   8608: BOOL IsWow64()
                   8609: {
                   8610:        BOOL bIsWow64 = FALSE;
                   8611: 
                   8612:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   8613:        //  (HANDLE, PBOOL);
                   8614: 
                   8615:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   8616: 
                   8617:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   8618:        const char funcName[] = "IsWow64Process";
                   8619:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   8620:                GetProcAddress(module, funcName);
                   8621: 
                   8622:        if (NULL != fnIsWow64Process)
                   8623:        {
                   8624:                if (!fnIsWow64Process(GetCurrentProcess(),
                   8625:                        &bIsWow64))
                   8626:                        //throw std::exception("Unknown error");
                   8627:                        printf("Unknown error\n");
                   8628:        }
                   8629:        return bIsWow64 != FALSE;
                   8630: }
                   8631: #endif
1.177     brouard  8632: 
1.191     brouard  8633: void syscompilerinfo(int logged)
1.167     brouard  8634:  {
                   8635:    /* #include "syscompilerinfo.h"*/
1.185     brouard  8636:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   8637:    /* /GS /W3 /Gy
                   8638:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   8639:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   8640:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  8641:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   8642:    */ 
                   8643:    /* 64 bits */
1.185     brouard  8644:    /*
                   8645:      /GS /W3 /Gy
                   8646:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   8647:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   8648:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   8649:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   8650:    /* Optimization are useless and O3 is slower than O2 */
                   8651:    /*
                   8652:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   8653:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   8654:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   8655:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   8656:    */
1.186     brouard  8657:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  8658:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   8659:       /PDB:"visual studio
                   8660:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   8661:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   8662:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   8663:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   8664:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   8665:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   8666:       uiAccess='false'"
                   8667:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   8668:       /NOLOGO /TLBID:1
                   8669:    */
1.177     brouard  8670: #if defined __INTEL_COMPILER
1.178     brouard  8671: #if defined(__GNUC__)
                   8672:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   8673: #endif
1.177     brouard  8674: #elif defined(__GNUC__) 
1.179     brouard  8675: #ifndef  __APPLE__
1.174     brouard  8676: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  8677: #endif
1.177     brouard  8678:    struct utsname sysInfo;
1.178     brouard  8679:    int cross = CROSS;
                   8680:    if (cross){
                   8681:           printf("Cross-");
1.191     brouard  8682:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  8683:    }
1.174     brouard  8684: #endif
                   8685: 
1.171     brouard  8686: #include <stdint.h>
1.178     brouard  8687: 
1.191     brouard  8688:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  8689: #if defined(__clang__)
1.191     brouard  8690:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  8691: #endif
                   8692: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  8693:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  8694: #endif
                   8695: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  8696:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  8697: #endif
                   8698: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  8699:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  8700: #endif
                   8701: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  8702:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  8703: #endif
                   8704: #if defined(_MSC_VER)
1.191     brouard  8705:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  8706: #endif
                   8707: #if defined(__PGI)
1.191     brouard  8708:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  8709: #endif
                   8710: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  8711:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  8712: #endif
1.191     brouard  8713:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  8714:    
1.167     brouard  8715: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   8716: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   8717:     // Windows (x64 and x86)
1.191     brouard  8718:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  8719: #elif __unix__ // all unices, not all compilers
                   8720:     // Unix
1.191     brouard  8721:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  8722: #elif __linux__
                   8723:     // linux
1.191     brouard  8724:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  8725: #elif __APPLE__
1.174     brouard  8726:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  8727:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  8728: #endif
                   8729: 
                   8730: /*  __MINGW32__          */
                   8731: /*  __CYGWIN__  */
                   8732: /* __MINGW64__  */
                   8733: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   8734: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   8735: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   8736: /* _WIN64  // Defined for applications for Win64. */
                   8737: /* _M_X64 // Defined for compilations that target x64 processors. */
                   8738: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  8739: 
1.167     brouard  8740: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  8741:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  8742: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  8743:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  8744: #else
1.191     brouard  8745:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  8746: #endif
                   8747: 
1.169     brouard  8748: #if defined(__GNUC__)
                   8749: # if defined(__GNUC_PATCHLEVEL__)
                   8750: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   8751:                             + __GNUC_MINOR__ * 100 \
                   8752:                             + __GNUC_PATCHLEVEL__)
                   8753: # else
                   8754: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   8755:                             + __GNUC_MINOR__ * 100)
                   8756: # endif
1.174     brouard  8757:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  8758:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  8759: 
                   8760:    if (uname(&sysInfo) != -1) {
                   8761:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  8762:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  8763:    }
                   8764:    else
                   8765:       perror("uname() error");
1.179     brouard  8766:    //#ifndef __INTEL_COMPILER 
                   8767: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  8768:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  8769:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  8770: #endif
1.169     brouard  8771: #endif
1.172     brouard  8772: 
                   8773:    //   void main()
                   8774:    //   {
1.169     brouard  8775: #if defined(_MSC_VER)
1.174     brouard  8776:    if (IsWow64()){
1.191     brouard  8777:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   8778:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  8779:    }
                   8780:    else{
1.191     brouard  8781:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   8782:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  8783:    }
1.172     brouard  8784:    //     printf("\nPress Enter to continue...");
                   8785:    //     getchar();
                   8786:    //   }
                   8787: 
1.169     brouard  8788: #endif
                   8789:    
1.167     brouard  8790: 
1.219     brouard  8791: }
1.136     brouard  8792: 
1.219     brouard  8793: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  8794:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
                   8795:   int i, j, k, i1 ;
1.202     brouard  8796:   /* double ftolpl = 1.e-10; */
1.180     brouard  8797:   double age, agebase, agelim;
1.203     brouard  8798:   double tot;
1.180     brouard  8799: 
1.202     brouard  8800:   strcpy(filerespl,"PL_");
                   8801:   strcat(filerespl,fileresu);
                   8802:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   8803:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   8804:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   8805:   }
1.227     brouard  8806:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   8807:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  8808:   pstamp(ficrespl);
1.203     brouard  8809:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  8810:   fprintf(ficrespl,"#Age ");
                   8811:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   8812:   fprintf(ficrespl,"\n");
1.180     brouard  8813:   
1.219     brouard  8814:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  8815: 
1.219     brouard  8816:   agebase=ageminpar;
                   8817:   agelim=agemaxpar;
1.180     brouard  8818: 
1.227     brouard  8819:   /* i1=pow(2,ncoveff); */
1.234   ! brouard  8820:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  8821:   if (cptcovn < 1){i1=1;}
1.180     brouard  8822: 
1.220     brouard  8823:   for(k=1; k<=i1;k++){
                   8824:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
1.180     brouard  8825:     /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
1.219     brouard  8826:     //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
1.220     brouard  8827:     /* k=k+1; */
1.219     brouard  8828:     /* to clean */
                   8829:     //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   8830:     fprintf(ficrespl,"#******");
                   8831:     printf("#******");
                   8832:     fprintf(ficlog,"#******");
1.227     brouard  8833:     for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   8834:       fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
1.219     brouard  8835:       printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8836:       fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8837:     }
                   8838:     fprintf(ficrespl,"******\n");
                   8839:     printf("******\n");
                   8840:     fprintf(ficlog,"******\n");
1.227     brouard  8841:     if(invalidvarcomb[k]){
                   8842:       printf("\nCombination (%d) ignored because no case \n",k); 
                   8843:       fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   8844:       fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
1.220     brouard  8845:                                                continue;
1.227     brouard  8846:     }
1.219     brouard  8847: 
                   8848:     fprintf(ficrespl,"#Age ");
1.227     brouard  8849:     for(j=1;j<=cptcoveff;j++) {
1.219     brouard  8850:       fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8851:     }
                   8852:     for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   8853:     fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  8854:     
1.219     brouard  8855:     for (age=agebase; age<=agelim; age++){
                   8856:       /* for (age=agebase; age<=agebase; age++){ */
                   8857:       prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k);
                   8858:       fprintf(ficrespl,"%.0f ",age );
1.227     brouard  8859:       for(j=1;j<=cptcoveff;j++)
                   8860:        fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.219     brouard  8861:       tot=0.;
                   8862:       for(i=1; i<=nlstate;i++){
1.227     brouard  8863:        tot +=  prlim[i][i];
                   8864:        fprintf(ficrespl," %.5f", prlim[i][i]);
1.219     brouard  8865:       }
                   8866:       fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   8867:     } /* Age */
                   8868:     /* was end of cptcod */
                   8869:   } /* cptcov */
                   8870:   return 0;
1.180     brouard  8871: }
                   8872: 
1.218     brouard  8873: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   8874:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   8875:        
                   8876:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   8877:    * at any age between ageminpar and agemaxpar
                   8878:         */
1.217     brouard  8879:   int i, j, k, i1 ;
                   8880:   /* double ftolpl = 1.e-10; */
                   8881:   double age, agebase, agelim;
                   8882:   double tot;
1.218     brouard  8883:   /* double ***mobaverage; */
                   8884:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  8885: 
                   8886:   strcpy(fileresplb,"PLB_");
                   8887:   strcat(fileresplb,fileresu);
                   8888:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   8889:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   8890:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   8891:   }
                   8892:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   8893:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   8894:   pstamp(ficresplb);
                   8895:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   8896:   fprintf(ficresplb,"#Age ");
                   8897:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   8898:   fprintf(ficresplb,"\n");
                   8899:   
1.218     brouard  8900:   
                   8901:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   8902:   
                   8903:   agebase=ageminpar;
                   8904:   agelim=agemaxpar;
                   8905:   
                   8906:   
1.227     brouard  8907:   i1=pow(2,cptcoveff);
1.218     brouard  8908:   if (cptcovn < 1){i1=1;}
1.227     brouard  8909:   
                   8910:   for(k=1; k<=i1;k++){ 
1.218     brouard  8911:     //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   8912:     fprintf(ficresplb,"#******");
                   8913:     printf("#******");
                   8914:     fprintf(ficlog,"#******");
1.227     brouard  8915:     for(j=1;j<=cptcoveff ;j++) {/* all covariates */
1.218     brouard  8916:       fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8917:       printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8918:       fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8919:     }
                   8920:     fprintf(ficresplb,"******\n");
                   8921:     printf("******\n");
                   8922:     fprintf(ficlog,"******\n");
1.227     brouard  8923:     if(invalidvarcomb[k]){
                   8924:       printf("\nCombination (%d) ignored because no cases \n",k); 
                   8925:       fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   8926:       fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   8927:       continue;
                   8928:     }
1.218     brouard  8929:     
                   8930:     fprintf(ficresplb,"#Age ");
1.227     brouard  8931:     for(j=1;j<=cptcoveff;j++) {
1.218     brouard  8932:       fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8933:     }
                   8934:     for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   8935:     fprintf(ficresplb,"Total Years_to_converge\n");
                   8936:     
                   8937:     
                   8938:     for (age=agebase; age<=agelim; age++){
                   8939:       /* for (age=agebase; age<=agebase; age++){ */
                   8940:       if(mobilavproj > 0){
                   8941:        /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   8942:        /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.227     brouard  8943:        bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k);
1.218     brouard  8944:       }else if (mobilavproj == 0){
1.227     brouard  8945:        printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   8946:        fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   8947:        exit(1);
1.218     brouard  8948:       }else{
1.227     brouard  8949:        /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   8950:        bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k);
1.218     brouard  8951:       }
                   8952:       fprintf(ficresplb,"%.0f ",age );
1.227     brouard  8953:       for(j=1;j<=cptcoveff;j++)
                   8954:        fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.218     brouard  8955:       tot=0.;
                   8956:       for(i=1; i<=nlstate;i++){
1.227     brouard  8957:        tot +=  bprlim[i][i];
                   8958:        fprintf(ficresplb," %.5f", bprlim[i][i]);
1.218     brouard  8959:       }
                   8960:       fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   8961:     } /* Age */
                   8962:     /* was end of cptcod */
                   8963:   } /* cptcov */
                   8964:   
                   8965:   /* hBijx(p, bage, fage); */
                   8966:   /* fclose(ficrespijb); */
                   8967:   
                   8968:   return 0;
1.217     brouard  8969: }
1.218     brouard  8970:  
1.180     brouard  8971: int hPijx(double *p, int bage, int fage){
                   8972:     /*------------- h Pij x at various ages ------------*/
                   8973: 
                   8974:   int stepsize;
                   8975:   int agelim;
                   8976:   int hstepm;
                   8977:   int nhstepm;
                   8978:   int h, i, i1, j, k;
                   8979: 
                   8980:   double agedeb;
                   8981:   double ***p3mat;
                   8982: 
1.201     brouard  8983:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  8984:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   8985:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   8986:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   8987:     }
                   8988:     printf("Computing pij: result on file '%s' \n", filerespij);
                   8989:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   8990:   
                   8991:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8992:     /*if (stepm<=24) stepsize=2;*/
                   8993: 
                   8994:     agelim=AGESUP;
                   8995:     hstepm=stepsize*YEARM; /* Every year of age */
                   8996:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  8997:                
1.180     brouard  8998:     /* hstepm=1;   aff par mois*/
                   8999:     pstamp(ficrespij);
                   9000:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  9001:     i1= pow(2,cptcoveff);
1.218     brouard  9002:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9003:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9004:                /*      k=k+1;  */
1.227     brouard  9005:     for (k=1; k <= (int) pow(2,cptcoveff); k++){
1.183     brouard  9006:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  9007:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  9008:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.183     brouard  9009:       fprintf(ficrespij,"******\n");
                   9010:       
                   9011:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   9012:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   9013:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   9014:        
                   9015:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  9016:        
1.183     brouard  9017:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9018:        oldm=oldms;savm=savms;
                   9019:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
                   9020:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   9021:        for(i=1; i<=nlstate;i++)
                   9022:          for(j=1; j<=nlstate+ndeath;j++)
                   9023:            fprintf(ficrespij," %1d-%1d",i,j);
                   9024:        fprintf(ficrespij,"\n");
                   9025:        for (h=0; h<=nhstepm; h++){
                   9026:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9027:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  9028:          for(i=1; i<=nlstate;i++)
                   9029:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  9030:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  9031:          fprintf(ficrespij,"\n");
                   9032:        }
1.183     brouard  9033:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9034:        fprintf(ficrespij,"\n");
                   9035:       }
1.180     brouard  9036:       /*}*/
                   9037:     }
1.218     brouard  9038:     return 0;
1.180     brouard  9039: }
1.218     brouard  9040:  
                   9041:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  9042:     /*------------- h Bij x at various ages ------------*/
                   9043: 
                   9044:   int stepsize;
1.218     brouard  9045:   /* int agelim; */
                   9046:        int ageminl;
1.217     brouard  9047:   int hstepm;
                   9048:   int nhstepm;
                   9049:   int h, i, i1, j, k;
1.218     brouard  9050:        
1.217     brouard  9051:   double agedeb;
                   9052:   double ***p3mat;
1.218     brouard  9053:        
                   9054:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   9055:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   9056:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9057:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9058:   }
                   9059:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   9060:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   9061:   
                   9062:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9063:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  9064:   
1.218     brouard  9065:   /* agelim=AGESUP; */
                   9066:   ageminl=30;
                   9067:   hstepm=stepsize*YEARM; /* Every year of age */
                   9068:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   9069:   
                   9070:   /* hstepm=1;   aff par mois*/
                   9071:   pstamp(ficrespijb);
                   9072:   fprintf(ficrespijb,"#****** h Pij x Back Probability to be in state i at age x-h being in j at x ");
1.227     brouard  9073:   i1= pow(2,cptcoveff);
1.218     brouard  9074:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9075:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9076:   /*   k=k+1;  */
1.227     brouard  9077:   for (k=1; k <= (int) pow(2,cptcoveff); k++){
1.218     brouard  9078:     fprintf(ficrespijb,"\n#****** ");
1.227     brouard  9079:     for(j=1;j<=cptcoveff;j++)
1.218     brouard  9080:       fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9081:     fprintf(ficrespijb,"******\n");
1.222     brouard  9082:     if(invalidvarcomb[k]){
                   9083:       fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   9084:       continue;
                   9085:     }
1.218     brouard  9086:     
                   9087:     /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   9088:     for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   9089:       /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   9090:       nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   9091:       nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   9092:       
                   9093:       /*         nhstepm=nhstepm*YEARM; aff par mois*/
                   9094:       
                   9095:       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9096:       /* oldm=oldms;savm=savms; */
                   9097:       /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9098:       hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k);
                   9099:       /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
                   9100:       fprintf(ficrespijb,"# Cov Agex agex-h hpijx with i,j=");
                   9101:       for(i=1; i<=nlstate;i++)
                   9102:        for(j=1; j<=nlstate+ndeath;j++)
                   9103:          fprintf(ficrespijb," %1d-%1d",i,j);
                   9104:       fprintf(ficrespijb,"\n");
                   9105:       for (h=0; h<=nhstepm; h++){
                   9106:        /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9107:        fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   9108:        /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
1.217     brouard  9109:        for(i=1; i<=nlstate;i++)
                   9110:          for(j=1; j<=nlstate+ndeath;j++)
1.218     brouard  9111:            fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
1.217     brouard  9112:        fprintf(ficrespijb,"\n");
                   9113:       }
1.218     brouard  9114:       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9115:       fprintf(ficrespijb,"\n");
1.217     brouard  9116:     }
1.218     brouard  9117:     /*}*/
                   9118:   }
                   9119:   return 0;
                   9120:  } /*  hBijx */
1.217     brouard  9121: 
1.180     brouard  9122: 
1.136     brouard  9123: /***********************************************/
                   9124: /**************** Main Program *****************/
                   9125: /***********************************************/
                   9126: 
                   9127: int main(int argc, char *argv[])
                   9128: {
                   9129: #ifdef GSL
                   9130:   const gsl_multimin_fminimizer_type *T;
                   9131:   size_t iteri = 0, it;
                   9132:   int rval = GSL_CONTINUE;
                   9133:   int status = GSL_SUCCESS;
                   9134:   double ssval;
                   9135: #endif
                   9136:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  9137:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  9138:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  9139:   int jj, ll, li, lj, lk;
1.136     brouard  9140:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  9141:   int num_filled;
1.136     brouard  9142:   int itimes;
                   9143:   int NDIM=2;
                   9144:   int vpopbased=0;
                   9145: 
1.164     brouard  9146:   char ca[32], cb[32];
1.136     brouard  9147:   /*  FILE *fichtm; *//* Html File */
                   9148:   /* FILE *ficgp;*/ /*Gnuplot File */
                   9149:   struct stat info;
1.191     brouard  9150:   double agedeb=0.;
1.194     brouard  9151: 
                   9152:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  9153:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  9154: 
1.165     brouard  9155:   double fret;
1.191     brouard  9156:   double dum=0.; /* Dummy variable */
1.136     brouard  9157:   double ***p3mat;
1.218     brouard  9158:   /* double ***mobaverage; */
1.164     brouard  9159: 
                   9160:   char line[MAXLINE];
1.197     brouard  9161:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   9162: 
1.234   ! brouard  9163:   char  modeltemp[MAXLINE];
1.230     brouard  9164:   char resultline[MAXLINE];
                   9165:   
1.136     brouard  9166:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  9167:   char *tok, *val; /* pathtot */
1.136     brouard  9168:   int firstobs=1, lastobs=10;
1.195     brouard  9169:   int c,  h , cpt, c2;
1.191     brouard  9170:   int jl=0;
                   9171:   int i1, j1, jk, stepsize=0;
1.194     brouard  9172:   int count=0;
                   9173: 
1.164     brouard  9174:   int *tab; 
1.136     brouard  9175:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  9176:   int backcast=0;
1.136     brouard  9177:   int mobilav=0,popforecast=0;
1.191     brouard  9178:   int hstepm=0, nhstepm=0;
1.136     brouard  9179:   int agemortsup;
                   9180:   float  sumlpop=0.;
                   9181:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   9182:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   9183: 
1.191     brouard  9184:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  9185:   double ftolpl=FTOL;
                   9186:   double **prlim;
1.217     brouard  9187:   double **bprlim;
1.136     brouard  9188:   double ***param; /* Matrix of parameters */
                   9189:   double  *p;
                   9190:   double **matcov; /* Matrix of covariance */
1.203     brouard  9191:   double **hess; /* Hessian matrix */
1.136     brouard  9192:   double ***delti3; /* Scale */
                   9193:   double *delti; /* Scale */
                   9194:   double ***eij, ***vareij;
                   9195:   double **varpl; /* Variances of prevalence limits by age */
                   9196:   double *epj, vepp;
1.164     brouard  9197: 
1.136     brouard  9198:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  9199:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   9200: 
1.136     brouard  9201:   double **ximort;
1.145     brouard  9202:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  9203:   int *dcwave;
                   9204: 
1.164     brouard  9205:   char z[1]="c";
1.136     brouard  9206: 
                   9207:   /*char  *strt;*/
                   9208:   char strtend[80];
1.126     brouard  9209: 
1.164     brouard  9210: 
1.126     brouard  9211: /*   setlocale (LC_ALL, ""); */
                   9212: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   9213: /*   textdomain (PACKAGE); */
                   9214: /*   setlocale (LC_CTYPE, ""); */
                   9215: /*   setlocale (LC_MESSAGES, ""); */
                   9216: 
                   9217:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  9218:   rstart_time = time(NULL);  
                   9219:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   9220:   start_time = *localtime(&rstart_time);
1.126     brouard  9221:   curr_time=start_time;
1.157     brouard  9222:   /*tml = *localtime(&start_time.tm_sec);*/
                   9223:   /* strcpy(strstart,asctime(&tml)); */
                   9224:   strcpy(strstart,asctime(&start_time));
1.126     brouard  9225: 
                   9226: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  9227: /*  tp.tm_sec = tp.tm_sec +86400; */
                   9228: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  9229: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   9230: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   9231: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  9232: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  9233: /*   strt=asctime(&tmg); */
                   9234: /*   printf("Time(after) =%s",strstart);  */
                   9235: /*  (void) time (&time_value);
                   9236: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   9237: *  tm = *localtime(&time_value);
                   9238: *  strstart=asctime(&tm);
                   9239: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   9240: */
                   9241: 
                   9242:   nberr=0; /* Number of errors and warnings */
                   9243:   nbwarn=0;
1.184     brouard  9244: #ifdef WIN32
                   9245:   _getcwd(pathcd, size);
                   9246: #else
1.126     brouard  9247:   getcwd(pathcd, size);
1.184     brouard  9248: #endif
1.191     brouard  9249:   syscompilerinfo(0);
1.196     brouard  9250:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  9251:   if(argc <=1){
                   9252:     printf("\nEnter the parameter file name: ");
1.205     brouard  9253:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   9254:       printf("ERROR Empty parameter file name\n");
                   9255:       goto end;
                   9256:     }
1.126     brouard  9257:     i=strlen(pathr);
                   9258:     if(pathr[i-1]=='\n')
                   9259:       pathr[i-1]='\0';
1.156     brouard  9260:     i=strlen(pathr);
1.205     brouard  9261:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  9262:       pathr[i-1]='\0';
1.205     brouard  9263:     }
                   9264:     i=strlen(pathr);
                   9265:     if( i==0 ){
                   9266:       printf("ERROR Empty parameter file name\n");
                   9267:       goto end;
                   9268:     }
                   9269:     for (tok = pathr; tok != NULL; ){
1.126     brouard  9270:       printf("Pathr |%s|\n",pathr);
                   9271:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   9272:       printf("val= |%s| pathr=%s\n",val,pathr);
                   9273:       strcpy (pathtot, val);
                   9274:       if(pathr[0] == '\0') break; /* Dirty */
                   9275:     }
                   9276:   }
                   9277:   else{
                   9278:     strcpy(pathtot,argv[1]);
                   9279:   }
                   9280:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   9281:   /*cygwin_split_path(pathtot,path,optionfile);
                   9282:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   9283:   /* cutv(path,optionfile,pathtot,'\\');*/
                   9284: 
                   9285:   /* Split argv[0], imach program to get pathimach */
                   9286:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   9287:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9288:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9289:  /*   strcpy(pathimach,argv[0]); */
                   9290:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   9291:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   9292:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  9293: #ifdef WIN32
                   9294:   _chdir(path); /* Can be a relative path */
                   9295:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   9296: #else
1.126     brouard  9297:   chdir(path); /* Can be a relative path */
1.184     brouard  9298:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   9299: #endif
                   9300:   printf("Current directory %s!\n",pathcd);
1.126     brouard  9301:   strcpy(command,"mkdir ");
                   9302:   strcat(command,optionfilefiname);
                   9303:   if((outcmd=system(command)) != 0){
1.169     brouard  9304:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  9305:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   9306:     /* fclose(ficlog); */
                   9307: /*     exit(1); */
                   9308:   }
                   9309: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   9310: /*     perror("mkdir"); */
                   9311: /*   } */
                   9312: 
                   9313:   /*-------- arguments in the command line --------*/
                   9314: 
1.186     brouard  9315:   /* Main Log file */
1.126     brouard  9316:   strcat(filelog, optionfilefiname);
                   9317:   strcat(filelog,".log");    /* */
                   9318:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   9319:     printf("Problem with logfile %s\n",filelog);
                   9320:     goto end;
                   9321:   }
                   9322:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  9323:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  9324:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   9325:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   9326:  path=%s \n\
                   9327:  optionfile=%s\n\
                   9328:  optionfilext=%s\n\
1.156     brouard  9329:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  9330: 
1.197     brouard  9331:   syscompilerinfo(1);
1.167     brouard  9332: 
1.126     brouard  9333:   printf("Local time (at start):%s",strstart);
                   9334:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   9335:   fflush(ficlog);
                   9336: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  9337: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  9338: 
                   9339:   /* */
                   9340:   strcpy(fileres,"r");
                   9341:   strcat(fileres, optionfilefiname);
1.201     brouard  9342:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  9343:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  9344:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  9345: 
1.186     brouard  9346:   /* Main ---------arguments file --------*/
1.126     brouard  9347: 
                   9348:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  9349:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   9350:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  9351:     fflush(ficlog);
1.149     brouard  9352:     /* goto end; */
                   9353:     exit(70); 
1.126     brouard  9354:   }
                   9355: 
                   9356: 
                   9357: 
                   9358:   strcpy(filereso,"o");
1.201     brouard  9359:   strcat(filereso,fileresu);
1.126     brouard  9360:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   9361:     printf("Problem with Output resultfile: %s\n", filereso);
                   9362:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   9363:     fflush(ficlog);
                   9364:     goto end;
                   9365:   }
                   9366: 
                   9367:   /* Reads comments: lines beginning with '#' */
                   9368:   numlinepar=0;
1.197     brouard  9369: 
                   9370:     /* First parameter line */
                   9371:   while(fgets(line, MAXLINE, ficpar)) {
                   9372:     /* If line starts with a # it is a comment */
                   9373:     if (line[0] == '#') {
                   9374:       numlinepar++;
                   9375:       fputs(line,stdout);
                   9376:       fputs(line,ficparo);
                   9377:       fputs(line,ficlog);
                   9378:       continue;
                   9379:     }else
                   9380:       break;
                   9381:   }
                   9382:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   9383:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   9384:     if (num_filled != 5) {
                   9385:       printf("Should be 5 parameters\n");
                   9386:     }
1.126     brouard  9387:     numlinepar++;
1.197     brouard  9388:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   9389:   }
                   9390:   /* Second parameter line */
                   9391:   while(fgets(line, MAXLINE, ficpar)) {
                   9392:     /* If line starts with a # it is a comment */
                   9393:     if (line[0] == '#') {
                   9394:       numlinepar++;
                   9395:       fputs(line,stdout);
                   9396:       fputs(line,ficparo);
                   9397:       fputs(line,ficlog);
                   9398:       continue;
                   9399:     }else
                   9400:       break;
                   9401:   }
1.223     brouard  9402:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   9403:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   9404:     if (num_filled != 11) {
                   9405:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  9406:       printf("but line=%s\n",line);
1.197     brouard  9407:     }
1.223     brouard  9408:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  9409:   }
1.203     brouard  9410:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  9411:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  9412:   /* Third parameter line */
                   9413:   while(fgets(line, MAXLINE, ficpar)) {
                   9414:     /* If line starts with a # it is a comment */
                   9415:     if (line[0] == '#') {
                   9416:       numlinepar++;
                   9417:       fputs(line,stdout);
                   9418:       fputs(line,ficparo);
                   9419:       fputs(line,ficlog);
                   9420:       continue;
                   9421:     }else
                   9422:       break;
                   9423:   }
1.201     brouard  9424:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
                   9425:     if (num_filled == 0)
                   9426:             model[0]='\0';
                   9427:     else if (num_filled != 1){
1.197     brouard  9428:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   9429:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   9430:       model[0]='\0';
                   9431:       goto end;
                   9432:     }
                   9433:     else{
                   9434:       if (model[0]=='+'){
                   9435:        for(i=1; i<=strlen(model);i++)
                   9436:          modeltemp[i-1]=model[i];
1.201     brouard  9437:        strcpy(model,modeltemp); 
1.197     brouard  9438:       }
                   9439:     }
1.199     brouard  9440:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  9441:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  9442:   }
                   9443:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   9444:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   9445:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  9446:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   9447:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  9448:   fflush(ficlog);
1.190     brouard  9449:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   9450:   if(model[0]=='#'){
1.187     brouard  9451:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   9452:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   9453:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   9454:     if(mle != -1){
                   9455:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   9456:       exit(1);
                   9457:     }
                   9458:   }
1.126     brouard  9459:   while((c=getc(ficpar))=='#' && c!= EOF){
                   9460:     ungetc(c,ficpar);
                   9461:     fgets(line, MAXLINE, ficpar);
                   9462:     numlinepar++;
1.195     brouard  9463:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   9464:       z[0]=line[1];
                   9465:     }
                   9466:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  9467:     fputs(line, stdout);
                   9468:     //puts(line);
1.126     brouard  9469:     fputs(line,ficparo);
                   9470:     fputs(line,ficlog);
                   9471:   }
                   9472:   ungetc(c,ficpar);
                   9473: 
                   9474:    
1.145     brouard  9475:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.225     brouard  9476:   coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
1.233     brouard  9477:   cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.225     brouard  9478:   cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
1.136     brouard  9479:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   9480:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   9481:      v1+v2*age+v2*v3 makes cptcovn = 3
                   9482:   */
                   9483:   if (strlen(model)>1) 
1.187     brouard  9484:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  9485:   else
1.187     brouard  9486:     ncovmodel=2; /* Constant and age */
1.133     brouard  9487:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   9488:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  9489:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   9490:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   9491:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   9492:     fflush(stdout);
                   9493:     fclose (ficlog);
                   9494:     goto end;
                   9495:   }
1.126     brouard  9496:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   9497:   delti=delti3[1][1];
                   9498:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   9499:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
                   9500:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  9501:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   9502:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  9503:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   9504:     fclose (ficparo);
                   9505:     fclose (ficlog);
                   9506:     goto end;
                   9507:     exit(0);
1.220     brouard  9508:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  9509:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  9510:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   9511:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  9512:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   9513:     matcov=matrix(1,npar,1,npar);
1.203     brouard  9514:     hess=matrix(1,npar,1,npar);
1.220     brouard  9515:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  9516:     /* Read guessed parameters */
1.126     brouard  9517:     /* Reads comments: lines beginning with '#' */
                   9518:     while((c=getc(ficpar))=='#' && c!= EOF){
                   9519:       ungetc(c,ficpar);
                   9520:       fgets(line, MAXLINE, ficpar);
                   9521:       numlinepar++;
1.141     brouard  9522:       fputs(line,stdout);
1.126     brouard  9523:       fputs(line,ficparo);
                   9524:       fputs(line,ficlog);
                   9525:     }
                   9526:     ungetc(c,ficpar);
                   9527:     
                   9528:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   9529:     for(i=1; i <=nlstate; i++){
1.234   ! brouard  9530:       j=0;
1.126     brouard  9531:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234   ! brouard  9532:        if(jj==i) continue;
        !          9533:        j++;
        !          9534:        fscanf(ficpar,"%1d%1d",&i1,&j1);
        !          9535:        if ((i1 != i) || (j1 != jj)){
        !          9536:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  9537: It might be a problem of design; if ncovcol and the model are correct\n \
                   9538: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234   ! brouard  9539:          exit(1);
        !          9540:        }
        !          9541:        fprintf(ficparo,"%1d%1d",i1,j1);
        !          9542:        if(mle==1)
        !          9543:          printf("%1d%1d",i,jj);
        !          9544:        fprintf(ficlog,"%1d%1d",i,jj);
        !          9545:        for(k=1; k<=ncovmodel;k++){
        !          9546:          fscanf(ficpar," %lf",&param[i][j][k]);
        !          9547:          if(mle==1){
        !          9548:            printf(" %lf",param[i][j][k]);
        !          9549:            fprintf(ficlog," %lf",param[i][j][k]);
        !          9550:          }
        !          9551:          else
        !          9552:            fprintf(ficlog," %lf",param[i][j][k]);
        !          9553:          fprintf(ficparo," %lf",param[i][j][k]);
        !          9554:        }
        !          9555:        fscanf(ficpar,"\n");
        !          9556:        numlinepar++;
        !          9557:        if(mle==1)
        !          9558:          printf("\n");
        !          9559:        fprintf(ficlog,"\n");
        !          9560:        fprintf(ficparo,"\n");
1.126     brouard  9561:       }
                   9562:     }  
                   9563:     fflush(ficlog);
1.234   ! brouard  9564:     
1.145     brouard  9565:     /* Reads scales values */
1.126     brouard  9566:     p=param[1][1];
                   9567:     
                   9568:     /* Reads comments: lines beginning with '#' */
                   9569:     while((c=getc(ficpar))=='#' && c!= EOF){
                   9570:       ungetc(c,ficpar);
                   9571:       fgets(line, MAXLINE, ficpar);
                   9572:       numlinepar++;
1.141     brouard  9573:       fputs(line,stdout);
1.126     brouard  9574:       fputs(line,ficparo);
                   9575:       fputs(line,ficlog);
                   9576:     }
                   9577:     ungetc(c,ficpar);
                   9578: 
                   9579:     for(i=1; i <=nlstate; i++){
                   9580:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234   ! brouard  9581:        fscanf(ficpar,"%1d%1d",&i1,&j1);
        !          9582:        if ( (i1-i) * (j1-j) != 0){
        !          9583:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
        !          9584:          exit(1);
        !          9585:        }
        !          9586:        printf("%1d%1d",i,j);
        !          9587:        fprintf(ficparo,"%1d%1d",i1,j1);
        !          9588:        fprintf(ficlog,"%1d%1d",i1,j1);
        !          9589:        for(k=1; k<=ncovmodel;k++){
        !          9590:          fscanf(ficpar,"%le",&delti3[i][j][k]);
        !          9591:          printf(" %le",delti3[i][j][k]);
        !          9592:          fprintf(ficparo," %le",delti3[i][j][k]);
        !          9593:          fprintf(ficlog," %le",delti3[i][j][k]);
        !          9594:        }
        !          9595:        fscanf(ficpar,"\n");
        !          9596:        numlinepar++;
        !          9597:        printf("\n");
        !          9598:        fprintf(ficparo,"\n");
        !          9599:        fprintf(ficlog,"\n");
1.126     brouard  9600:       }
                   9601:     }
                   9602:     fflush(ficlog);
1.234   ! brouard  9603:     
1.145     brouard  9604:     /* Reads covariance matrix */
1.126     brouard  9605:     delti=delti3[1][1];
1.220     brouard  9606:                
                   9607:                
1.126     brouard  9608:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  9609:                
1.126     brouard  9610:     /* Reads comments: lines beginning with '#' */
                   9611:     while((c=getc(ficpar))=='#' && c!= EOF){
                   9612:       ungetc(c,ficpar);
                   9613:       fgets(line, MAXLINE, ficpar);
                   9614:       numlinepar++;
1.141     brouard  9615:       fputs(line,stdout);
1.126     brouard  9616:       fputs(line,ficparo);
                   9617:       fputs(line,ficlog);
                   9618:     }
                   9619:     ungetc(c,ficpar);
1.220     brouard  9620:                
1.126     brouard  9621:     matcov=matrix(1,npar,1,npar);
1.203     brouard  9622:     hess=matrix(1,npar,1,npar);
1.131     brouard  9623:     for(i=1; i <=npar; i++)
                   9624:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  9625:                
1.194     brouard  9626:     /* Scans npar lines */
1.126     brouard  9627:     for(i=1; i <=npar; i++){
1.226     brouard  9628:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  9629:       if(count != 3){
1.226     brouard  9630:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  9631: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   9632: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  9633:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  9634: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   9635: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  9636:        exit(1);
1.220     brouard  9637:       }else{
1.226     brouard  9638:        if(mle==1)
                   9639:          printf("%1d%1d%d",i1,j1,jk);
                   9640:       }
                   9641:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   9642:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  9643:       for(j=1; j <=i; j++){
1.226     brouard  9644:        fscanf(ficpar," %le",&matcov[i][j]);
                   9645:        if(mle==1){
                   9646:          printf(" %.5le",matcov[i][j]);
                   9647:        }
                   9648:        fprintf(ficlog," %.5le",matcov[i][j]);
                   9649:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  9650:       }
                   9651:       fscanf(ficpar,"\n");
                   9652:       numlinepar++;
                   9653:       if(mle==1)
1.220     brouard  9654:                                printf("\n");
1.126     brouard  9655:       fprintf(ficlog,"\n");
                   9656:       fprintf(ficparo,"\n");
                   9657:     }
1.194     brouard  9658:     /* End of read covariance matrix npar lines */
1.126     brouard  9659:     for(i=1; i <=npar; i++)
                   9660:       for(j=i+1;j<=npar;j++)
1.226     brouard  9661:        matcov[i][j]=matcov[j][i];
1.126     brouard  9662:     
                   9663:     if(mle==1)
                   9664:       printf("\n");
                   9665:     fprintf(ficlog,"\n");
                   9666:     
                   9667:     fflush(ficlog);
                   9668:     
                   9669:     /*-------- Rewriting parameter file ----------*/
                   9670:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   9671:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   9672:     strcat(rfileres,".");    /* */
                   9673:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   9674:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  9675:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   9676:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  9677:     }
                   9678:     fprintf(ficres,"#%s\n",version);
                   9679:   }    /* End of mle != -3 */
1.218     brouard  9680:   
1.186     brouard  9681:   /*  Main data
                   9682:    */
1.126     brouard  9683:   n= lastobs;
                   9684:   num=lvector(1,n);
                   9685:   moisnais=vector(1,n);
                   9686:   annais=vector(1,n);
                   9687:   moisdc=vector(1,n);
                   9688:   andc=vector(1,n);
1.220     brouard  9689:   weight=vector(1,n);
1.126     brouard  9690:   agedc=vector(1,n);
                   9691:   cod=ivector(1,n);
1.220     brouard  9692:   for(i=1;i<=n;i++){
1.234   ! brouard  9693:     num[i]=0;
        !          9694:     moisnais[i]=0;
        !          9695:     annais[i]=0;
        !          9696:     moisdc[i]=0;
        !          9697:     andc[i]=0;
        !          9698:     agedc[i]=0;
        !          9699:     cod[i]=0;
        !          9700:     weight[i]=1.0; /* Equal weights, 1 by default */
        !          9701:   }
1.126     brouard  9702:   mint=matrix(1,maxwav,1,n);
                   9703:   anint=matrix(1,maxwav,1,n);
1.131     brouard  9704:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  9705:   tab=ivector(1,NCOVMAX);
1.144     brouard  9706:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  9707:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  9708: 
1.136     brouard  9709:   /* Reads data from file datafile */
                   9710:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   9711:     goto end;
                   9712: 
                   9713:   /* Calculation of the number of parameters from char model */
1.234   ! brouard  9714:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  9715:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   9716:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   9717:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   9718:        k=1 Tvar[1]=2 (from V2)
1.234   ! brouard  9719:   */
        !          9720:   
        !          9721:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
        !          9722:   TvarsDind=ivector(1,NCOVMAX); /*  */
        !          9723:   TvarsD=ivector(1,NCOVMAX); /*  */
        !          9724:   TvarsQind=ivector(1,NCOVMAX); /*  */
        !          9725:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  9726:   TvarF=ivector(1,NCOVMAX); /*  */
                   9727:   TvarFind=ivector(1,NCOVMAX); /*  */
                   9728:   TvarV=ivector(1,NCOVMAX); /*  */
                   9729:   TvarVind=ivector(1,NCOVMAX); /*  */
                   9730:   TvarA=ivector(1,NCOVMAX); /*  */
                   9731:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  9732:   TvarFD=ivector(1,NCOVMAX); /*  */
                   9733:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   9734:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   9735:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   9736:   TvarVD=ivector(1,NCOVMAX); /*  */
                   9737:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   9738:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   9739:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   9740: 
1.230     brouard  9741:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  9742:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  9743:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   9744:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   9745:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  9746:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   9747:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   9748:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   9749:   */
                   9750:   /* For model-covariate k tells which data-covariate to use but
                   9751:     because this model-covariate is a construction we invent a new column
                   9752:     ncovcol + k1
                   9753:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   9754:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  9755:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   9756:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  9757:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   9758:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  9759:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  9760:   */
1.145     brouard  9761:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   9762:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  9763:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   9764:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  9765:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  9766:                         4 covariates (3 plus signs)
                   9767:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   9768:                      */  
1.230     brouard  9769:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  9770:                                * individual dummy, fixed or varying:
                   9771:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   9772:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  9773:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   9774:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   9775:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   9776:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   9777:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  9778:                                * individual quantitative, fixed or varying:
                   9779:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   9780:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   9781:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  9782: /* Main decodemodel */
                   9783: 
1.187     brouard  9784: 
1.223     brouard  9785:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  9786:     goto end;
                   9787: 
1.137     brouard  9788:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   9789:     nbwarn++;
                   9790:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   9791:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   9792:   }
1.136     brouard  9793:     /*  if(mle==1){*/
1.137     brouard  9794:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   9795:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  9796:   }
                   9797: 
                   9798:     /*-calculation of age at interview from date of interview and age at death -*/
                   9799:   agev=matrix(1,maxwav,1,imx);
                   9800: 
                   9801:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   9802:     goto end;
                   9803: 
1.126     brouard  9804: 
1.136     brouard  9805:   agegomp=(int)agemin;
                   9806:   free_vector(moisnais,1,n);
                   9807:   free_vector(annais,1,n);
1.126     brouard  9808:   /* free_matrix(mint,1,maxwav,1,n);
                   9809:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  9810:   /* free_vector(moisdc,1,n); */
                   9811:   /* free_vector(andc,1,n); */
1.145     brouard  9812:   /* */
                   9813:   
1.126     brouard  9814:   wav=ivector(1,imx);
1.214     brouard  9815:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   9816:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   9817:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   9818:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   9819:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   9820:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  9821:    
                   9822:   /* Concatenates waves */
1.214     brouard  9823:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   9824:      Death is a valid wave (if date is known).
                   9825:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   9826:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   9827:      and mw[mi+1][i]. dh depends on stepm.
                   9828:   */
                   9829: 
1.126     brouard  9830:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.145     brouard  9831:   /* */
                   9832:  
1.215     brouard  9833:   free_vector(moisdc,1,n);
                   9834:   free_vector(andc,1,n);
                   9835: 
1.126     brouard  9836:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   9837:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   9838:   ncodemax[1]=1;
1.145     brouard  9839:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  9840:   cptcoveff=0;
1.220     brouard  9841:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   9842:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  9843:   }
                   9844:   
                   9845:   ncovcombmax=pow(2,cptcoveff);
                   9846:   invalidvarcomb=ivector(1, ncovcombmax); 
                   9847:   for(i=1;i<ncovcombmax;i++)
                   9848:     invalidvarcomb[i]=0;
                   9849:   
1.211     brouard  9850:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  9851:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  9852:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  9853:   
1.200     brouard  9854:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  9855:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  9856:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  9857:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   9858:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   9859:    * (currently 0 or 1) in the data.
                   9860:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   9861:    * corresponding modality (h,j).
                   9862:    */
                   9863: 
1.145     brouard  9864:   h=0;
                   9865:   /*if (cptcovn > 0) */
1.126     brouard  9866:   m=pow(2,cptcoveff);
                   9867:  
1.144     brouard  9868:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  9869:           * For k=4 covariates, h goes from 1 to m=2**k
                   9870:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   9871:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  9872:           *     h\k   1     2     3     4
1.143     brouard  9873:           *______________________________  
                   9874:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   9875:           *     2     2     1     1     1
                   9876:           *     3 i=2 1     2     1     1
                   9877:           *     4     2     2     1     1
                   9878:           *     5 i=3 1 i=2 1     2     1
                   9879:           *     6     2     1     2     1
                   9880:           *     7 i=4 1     2     2     1
                   9881:           *     8     2     2     2     1
1.197     brouard  9882:           *     9 i=5 1 i=3 1 i=2 1     2
                   9883:           *    10     2     1     1     2
                   9884:           *    11 i=6 1     2     1     2
                   9885:           *    12     2     2     1     2
                   9886:           *    13 i=7 1 i=4 1     2     2    
                   9887:           *    14     2     1     2     2
                   9888:           *    15 i=8 1     2     2     2
                   9889:           *    16     2     2     2     2
1.143     brouard  9890:           */
1.212     brouard  9891:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  9892:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   9893:      * and the value of each covariate?
                   9894:      * V1=1, V2=1, V3=2, V4=1 ?
                   9895:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   9896:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   9897:      * In order to get the real value in the data, we use nbcode
                   9898:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   9899:      * We are keeping this crazy system in order to be able (in the future?) 
                   9900:      * to have more than 2 values (0 or 1) for a covariate.
                   9901:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   9902:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   9903:      *              bbbbbbbb
                   9904:      *              76543210     
                   9905:      *   h-1        00000101 (6-1=5)
1.219     brouard  9906:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  9907:      *           &
                   9908:      *     1        00000001 (1)
1.219     brouard  9909:      *              00000000        = 1 & ((h-1) >> (k-1))
                   9910:      *          +1= 00000001 =1 
1.211     brouard  9911:      *
                   9912:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   9913:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   9914:      *    >>k'            11
                   9915:      *          &   00000001
                   9916:      *            = 00000001
                   9917:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   9918:      * Reverse h=6 and m=16?
                   9919:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   9920:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   9921:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   9922:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   9923:      * V3=decodtabm(14,3,2**4)=2
                   9924:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   9925:      *(h-1) >> (j-1)    0011 =13 >> 2
                   9926:      *          &1 000000001
                   9927:      *           = 000000001
                   9928:      *         +1= 000000010 =2
                   9929:      *                  2211
                   9930:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   9931:      *                  V3=2
1.220     brouard  9932:                 * codtabm and decodtabm are identical
1.211     brouard  9933:      */
                   9934: 
1.145     brouard  9935: 
                   9936:  free_ivector(Ndum,-1,NCOVMAX);
                   9937: 
                   9938: 
1.126     brouard  9939:     
1.186     brouard  9940:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  9941:   strcpy(optionfilegnuplot,optionfilefiname);
                   9942:   if(mle==-3)
1.201     brouard  9943:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  9944:   strcat(optionfilegnuplot,".gp");
                   9945: 
                   9946:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   9947:     printf("Problem with file %s",optionfilegnuplot);
                   9948:   }
                   9949:   else{
1.204     brouard  9950:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  9951:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  9952:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   9953:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  9954:   }
                   9955:   /*  fclose(ficgp);*/
1.186     brouard  9956: 
                   9957: 
                   9958:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  9959: 
                   9960:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   9961:   if(mle==-3)
1.201     brouard  9962:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  9963:   strcat(optionfilehtm,".htm");
                   9964:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  9965:     printf("Problem with %s \n",optionfilehtm);
                   9966:     exit(0);
1.126     brouard  9967:   }
                   9968: 
                   9969:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   9970:   strcat(optionfilehtmcov,"-cov.htm");
                   9971:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   9972:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   9973:   }
                   9974:   else{
                   9975:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   9976: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  9977: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  9978:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   9979:   }
                   9980: 
1.213     brouard  9981:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  9982: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   9983: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  9984: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  9985: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  9986: \n\
                   9987: <hr  size=\"2\" color=\"#EC5E5E\">\
                   9988:  <ul><li><h4>Parameter files</h4>\n\
                   9989:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   9990:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   9991:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   9992:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   9993:  - Date and time at start: %s</ul>\n",\
                   9994:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   9995:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   9996:          fileres,fileres,\
                   9997:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   9998:   fflush(fichtm);
                   9999: 
                   10000:   strcpy(pathr,path);
                   10001:   strcat(pathr,optionfilefiname);
1.184     brouard  10002: #ifdef WIN32
                   10003:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   10004: #else
1.126     brouard  10005:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  10006: #endif
                   10007:          
1.126     brouard  10008:   
1.220     brouard  10009:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   10010:                 and for any valid combination of covariates
1.126     brouard  10011:      and prints on file fileres'p'. */
1.227     brouard  10012:   freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
                   10013:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  10014: 
                   10015:   fprintf(fichtm,"\n");
                   10016:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   10017: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   10018: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   10019:          imx,agemin,agemax,jmin,jmax,jmean);
                   10020:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.220     brouard  10021:        oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10022:        newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10023:        savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10024:        oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  10025: 
1.126     brouard  10026:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   10027:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   10028:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   10029: 
                   10030:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  10031:   /* For mortality only */
1.126     brouard  10032:   if (mle==-3){
1.136     brouard  10033:     ximort=matrix(1,NDIM,1,NDIM); 
1.220     brouard  10034:                for(i=1;i<=NDIM;i++)
                   10035:                        for(j=1;j<=NDIM;j++)
                   10036:                                ximort[i][j]=0.;
1.186     brouard  10037:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  10038:     cens=ivector(1,n);
                   10039:     ageexmed=vector(1,n);
                   10040:     agecens=vector(1,n);
                   10041:     dcwave=ivector(1,n);
1.223     brouard  10042:                
1.126     brouard  10043:     for (i=1; i<=imx; i++){
                   10044:       dcwave[i]=-1;
                   10045:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  10046:        if (s[m][i]>nlstate) {
                   10047:          dcwave[i]=m;
                   10048:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   10049:          break;
                   10050:        }
1.126     brouard  10051:     }
1.226     brouard  10052:     
1.126     brouard  10053:     for (i=1; i<=imx; i++) {
                   10054:       if (wav[i]>0){
1.226     brouard  10055:        ageexmed[i]=agev[mw[1][i]][i];
                   10056:        j=wav[i];
                   10057:        agecens[i]=1.; 
                   10058:        
                   10059:        if (ageexmed[i]> 1 && wav[i] > 0){
                   10060:          agecens[i]=agev[mw[j][i]][i];
                   10061:          cens[i]= 1;
                   10062:        }else if (ageexmed[i]< 1) 
                   10063:          cens[i]= -1;
                   10064:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   10065:          cens[i]=0 ;
1.126     brouard  10066:       }
                   10067:       else cens[i]=-1;
                   10068:     }
                   10069:     
                   10070:     for (i=1;i<=NDIM;i++) {
                   10071:       for (j=1;j<=NDIM;j++)
1.226     brouard  10072:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  10073:     }
                   10074:     
1.145     brouard  10075:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  10076:     /*printf("%lf %lf", p[1], p[2]);*/
                   10077:     
                   10078:     
1.136     brouard  10079: #ifdef GSL
                   10080:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  10081: #else
1.126     brouard  10082:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  10083: #endif
1.201     brouard  10084:     strcpy(filerespow,"POW-MORT_"); 
                   10085:     strcat(filerespow,fileresu);
1.126     brouard  10086:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   10087:       printf("Problem with resultfile: %s\n", filerespow);
                   10088:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   10089:     }
1.136     brouard  10090: #ifdef GSL
                   10091:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  10092: #else
1.126     brouard  10093:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  10094: #endif
1.126     brouard  10095:     /*  for (i=1;i<=nlstate;i++)
                   10096:        for(j=1;j<=nlstate+ndeath;j++)
                   10097:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   10098:     */
                   10099:     fprintf(ficrespow,"\n");
1.136     brouard  10100: #ifdef GSL
                   10101:     /* gsl starts here */ 
                   10102:     T = gsl_multimin_fminimizer_nmsimplex;
                   10103:     gsl_multimin_fminimizer *sfm = NULL;
                   10104:     gsl_vector *ss, *x;
                   10105:     gsl_multimin_function minex_func;
                   10106: 
                   10107:     /* Initial vertex size vector */
                   10108:     ss = gsl_vector_alloc (NDIM);
                   10109:     
                   10110:     if (ss == NULL){
                   10111:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   10112:     }
                   10113:     /* Set all step sizes to 1 */
                   10114:     gsl_vector_set_all (ss, 0.001);
                   10115: 
                   10116:     /* Starting point */
1.126     brouard  10117:     
1.136     brouard  10118:     x = gsl_vector_alloc (NDIM);
                   10119:     
                   10120:     if (x == NULL){
                   10121:       gsl_vector_free(ss);
                   10122:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   10123:     }
                   10124:   
                   10125:     /* Initialize method and iterate */
                   10126:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  10127:     /*     gsl_vector_set(x, 0, 0.0268); */
                   10128:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  10129:     gsl_vector_set(x, 0, p[1]);
                   10130:     gsl_vector_set(x, 1, p[2]);
                   10131: 
                   10132:     minex_func.f = &gompertz_f;
                   10133:     minex_func.n = NDIM;
                   10134:     minex_func.params = (void *)&p; /* ??? */
                   10135:     
                   10136:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   10137:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   10138:     
                   10139:     printf("Iterations beginning .....\n\n");
                   10140:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   10141: 
                   10142:     iteri=0;
                   10143:     while (rval == GSL_CONTINUE){
                   10144:       iteri++;
                   10145:       status = gsl_multimin_fminimizer_iterate(sfm);
                   10146:       
                   10147:       if (status) printf("error: %s\n", gsl_strerror (status));
                   10148:       fflush(0);
                   10149:       
                   10150:       if (status) 
                   10151:         break;
                   10152:       
                   10153:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   10154:       ssval = gsl_multimin_fminimizer_size (sfm);
                   10155:       
                   10156:       if (rval == GSL_SUCCESS)
                   10157:         printf ("converged to a local maximum at\n");
                   10158:       
                   10159:       printf("%5d ", iteri);
                   10160:       for (it = 0; it < NDIM; it++){
                   10161:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   10162:       }
                   10163:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   10164:     }
                   10165:     
                   10166:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   10167:     
                   10168:     gsl_vector_free(x); /* initial values */
                   10169:     gsl_vector_free(ss); /* inital step size */
                   10170:     for (it=0; it<NDIM; it++){
                   10171:       p[it+1]=gsl_vector_get(sfm->x,it);
                   10172:       fprintf(ficrespow," %.12lf", p[it]);
                   10173:     }
                   10174:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   10175: #endif
                   10176: #ifdef POWELL
                   10177:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   10178: #endif  
1.126     brouard  10179:     fclose(ficrespow);
                   10180:     
1.203     brouard  10181:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  10182: 
                   10183:     for(i=1; i <=NDIM; i++)
                   10184:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  10185:                                matcov[i][j]=matcov[j][i];
1.126     brouard  10186:     
                   10187:     printf("\nCovariance matrix\n ");
1.203     brouard  10188:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  10189:     for(i=1; i <=NDIM; i++) {
                   10190:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  10191:                                printf("%f ",matcov[i][j]);
                   10192:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  10193:       }
1.203     brouard  10194:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  10195:     }
                   10196:     
                   10197:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  10198:     for (i=1;i<=NDIM;i++) {
1.126     brouard  10199:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  10200:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   10201:     }
1.126     brouard  10202:     lsurv=vector(1,AGESUP);
                   10203:     lpop=vector(1,AGESUP);
                   10204:     tpop=vector(1,AGESUP);
                   10205:     lsurv[agegomp]=100000;
                   10206:     
                   10207:     for (k=agegomp;k<=AGESUP;k++) {
                   10208:       agemortsup=k;
                   10209:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   10210:     }
                   10211:     
                   10212:     for (k=agegomp;k<agemortsup;k++)
                   10213:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   10214:     
                   10215:     for (k=agegomp;k<agemortsup;k++){
                   10216:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   10217:       sumlpop=sumlpop+lpop[k];
                   10218:     }
                   10219:     
                   10220:     tpop[agegomp]=sumlpop;
                   10221:     for (k=agegomp;k<(agemortsup-3);k++){
                   10222:       /*  tpop[k+1]=2;*/
                   10223:       tpop[k+1]=tpop[k]-lpop[k];
                   10224:     }
                   10225:     
                   10226:     
                   10227:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   10228:     for (k=agegomp;k<(agemortsup-2);k++) 
                   10229:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   10230:     
                   10231:     
                   10232:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  10233:                ageminpar=50;
                   10234:                agemaxpar=100;
1.194     brouard  10235:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   10236:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10237: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10238: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   10239:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10240: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10241: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10242:     }else{
                   10243:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   10244:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  10245:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  10246:                }
1.201     brouard  10247:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  10248:                     stepm, weightopt,\
                   10249:                     model,imx,p,matcov,agemortsup);
                   10250:     
                   10251:     free_vector(lsurv,1,AGESUP);
                   10252:     free_vector(lpop,1,AGESUP);
                   10253:     free_vector(tpop,1,AGESUP);
1.220     brouard  10254:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  10255:     free_ivector(cens,1,n);
                   10256:     free_vector(agecens,1,n);
                   10257:     free_ivector(dcwave,1,n);
1.220     brouard  10258: #ifdef GSL
1.136     brouard  10259: #endif
1.186     brouard  10260:   } /* Endof if mle==-3 mortality only */
1.205     brouard  10261:   /* Standard  */
                   10262:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   10263:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10264:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  10265:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  10266:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10267:     for (k=1; k<=npar;k++)
                   10268:       printf(" %d %8.5f",k,p[k]);
                   10269:     printf("\n");
1.205     brouard  10270:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   10271:       /* mlikeli uses func not funcone */
                   10272:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   10273:     }
                   10274:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   10275:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10276:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   10277:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10278:     }
                   10279:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  10280:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10281:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10282:     for (k=1; k<=npar;k++)
                   10283:       printf(" %d %8.5f",k,p[k]);
                   10284:     printf("\n");
                   10285:     
                   10286:     /*--------- results files --------------*/
1.224     brouard  10287:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  10288:     
                   10289:     
                   10290:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10291:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10292:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10293:     for(i=1,jk=1; i <=nlstate; i++){
                   10294:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  10295:        if (k != i) {
                   10296:          printf("%d%d ",i,k);
                   10297:          fprintf(ficlog,"%d%d ",i,k);
                   10298:          fprintf(ficres,"%1d%1d ",i,k);
                   10299:          for(j=1; j <=ncovmodel; j++){
                   10300:            printf("%12.7f ",p[jk]);
                   10301:            fprintf(ficlog,"%12.7f ",p[jk]);
                   10302:            fprintf(ficres,"%12.7f ",p[jk]);
                   10303:            jk++; 
                   10304:          }
                   10305:          printf("\n");
                   10306:          fprintf(ficlog,"\n");
                   10307:          fprintf(ficres,"\n");
                   10308:        }
1.126     brouard  10309:       }
                   10310:     }
1.203     brouard  10311:     if(mle != 0){
                   10312:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  10313:       ftolhess=ftol; /* Usually correct */
1.203     brouard  10314:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   10315:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10316:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10317:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  10318:        for(k=1; k <=(nlstate+ndeath); k++){
                   10319:          if (k != i) {
                   10320:            printf("%d%d ",i,k);
                   10321:            fprintf(ficlog,"%d%d ",i,k);
                   10322:            for(j=1; j <=ncovmodel; j++){
                   10323:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10324:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10325:              jk++; 
                   10326:            }
                   10327:            printf("\n");
                   10328:            fprintf(ficlog,"\n");
                   10329:          }
                   10330:        }
1.193     brouard  10331:       }
1.203     brouard  10332:     } /* end of hesscov and Wald tests */
1.225     brouard  10333:     
1.203     brouard  10334:     /*  */
1.126     brouard  10335:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   10336:     printf("# Scales (for hessian or gradient estimation)\n");
                   10337:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   10338:     for(i=1,jk=1; i <=nlstate; i++){
                   10339:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  10340:        if (j!=i) {
                   10341:          fprintf(ficres,"%1d%1d",i,j);
                   10342:          printf("%1d%1d",i,j);
                   10343:          fprintf(ficlog,"%1d%1d",i,j);
                   10344:          for(k=1; k<=ncovmodel;k++){
                   10345:            printf(" %.5e",delti[jk]);
                   10346:            fprintf(ficlog," %.5e",delti[jk]);
                   10347:            fprintf(ficres," %.5e",delti[jk]);
                   10348:            jk++;
                   10349:          }
                   10350:          printf("\n");
                   10351:          fprintf(ficlog,"\n");
                   10352:          fprintf(ficres,"\n");
                   10353:        }
1.126     brouard  10354:       }
                   10355:     }
                   10356:     
                   10357:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  10358:     if(mle >= 1) /* To big for the screen */
1.126     brouard  10359:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   10360:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   10361:     /* # 121 Var(a12)\n\ */
                   10362:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   10363:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   10364:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   10365:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   10366:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   10367:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   10368:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   10369:     
                   10370:     
                   10371:     /* Just to have a covariance matrix which will be more understandable
                   10372:        even is we still don't want to manage dictionary of variables
                   10373:     */
                   10374:     for(itimes=1;itimes<=2;itimes++){
                   10375:       jj=0;
                   10376:       for(i=1; i <=nlstate; i++){
1.225     brouard  10377:        for(j=1; j <=nlstate+ndeath; j++){
                   10378:          if(j==i) continue;
                   10379:          for(k=1; k<=ncovmodel;k++){
                   10380:            jj++;
                   10381:            ca[0]= k+'a'-1;ca[1]='\0';
                   10382:            if(itimes==1){
                   10383:              if(mle>=1)
                   10384:                printf("#%1d%1d%d",i,j,k);
                   10385:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   10386:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   10387:            }else{
                   10388:              if(mle>=1)
                   10389:                printf("%1d%1d%d",i,j,k);
                   10390:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   10391:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   10392:            }
                   10393:            ll=0;
                   10394:            for(li=1;li <=nlstate; li++){
                   10395:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   10396:                if(lj==li) continue;
                   10397:                for(lk=1;lk<=ncovmodel;lk++){
                   10398:                  ll++;
                   10399:                  if(ll<=jj){
                   10400:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   10401:                    if(ll<jj){
                   10402:                      if(itimes==1){
                   10403:                        if(mle>=1)
                   10404:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10405:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10406:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10407:                      }else{
                   10408:                        if(mle>=1)
                   10409:                          printf(" %.5e",matcov[jj][ll]); 
                   10410:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   10411:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   10412:                      }
                   10413:                    }else{
                   10414:                      if(itimes==1){
                   10415:                        if(mle>=1)
                   10416:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   10417:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   10418:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   10419:                      }else{
                   10420:                        if(mle>=1)
                   10421:                          printf(" %.7e",matcov[jj][ll]); 
                   10422:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   10423:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   10424:                      }
                   10425:                    }
                   10426:                  }
                   10427:                } /* end lk */
                   10428:              } /* end lj */
                   10429:            } /* end li */
                   10430:            if(mle>=1)
                   10431:              printf("\n");
                   10432:            fprintf(ficlog,"\n");
                   10433:            fprintf(ficres,"\n");
                   10434:            numlinepar++;
                   10435:          } /* end k*/
                   10436:        } /*end j */
1.126     brouard  10437:       } /* end i */
                   10438:     } /* end itimes */
                   10439:     
                   10440:     fflush(ficlog);
                   10441:     fflush(ficres);
1.225     brouard  10442:     while(fgets(line, MAXLINE, ficpar)) {
                   10443:       /* If line starts with a # it is a comment */
                   10444:       if (line[0] == '#') {
                   10445:        numlinepar++;
                   10446:        fputs(line,stdout);
                   10447:        fputs(line,ficparo);
                   10448:        fputs(line,ficlog);
                   10449:        continue;
                   10450:       }else
                   10451:        break;
                   10452:     }
                   10453:     
1.209     brouard  10454:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   10455:     /*   ungetc(c,ficpar); */
                   10456:     /*   fgets(line, MAXLINE, ficpar); */
                   10457:     /*   fputs(line,stdout); */
                   10458:     /*   fputs(line,ficparo); */
                   10459:     /* } */
                   10460:     /* ungetc(c,ficpar); */
1.126     brouard  10461:     
                   10462:     estepm=0;
1.209     brouard  10463:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  10464:       
                   10465:       if (num_filled != 6) {
                   10466:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   10467:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   10468:        goto end;
                   10469:       }
                   10470:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   10471:     }
                   10472:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   10473:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   10474:     
1.209     brouard  10475:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  10476:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   10477:     if (fage <= 2) {
                   10478:       bage = ageminpar;
                   10479:       fage = agemaxpar;
                   10480:     }
                   10481:     
                   10482:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  10483:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   10484:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  10485:                
1.186     brouard  10486:     /* Other stuffs, more or less useful */    
1.126     brouard  10487:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10488:       ungetc(c,ficpar);
                   10489:       fgets(line, MAXLINE, ficpar);
1.141     brouard  10490:       fputs(line,stdout);
1.126     brouard  10491:       fputs(line,ficparo);
                   10492:     }
                   10493:     ungetc(c,ficpar);
                   10494:     
                   10495:     fscanf(ficpar,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav);
                   10496:     fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10497:     fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10498:     printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10499:     fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10500:     
                   10501:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10502:       ungetc(c,ficpar);
                   10503:       fgets(line, MAXLINE, ficpar);
1.141     brouard  10504:       fputs(line,stdout);
1.126     brouard  10505:       fputs(line,ficparo);
                   10506:     }
                   10507:     ungetc(c,ficpar);
                   10508:     
                   10509:     
                   10510:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   10511:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   10512:     
                   10513:     fscanf(ficpar,"pop_based=%d\n",&popbased);
1.193     brouard  10514:     fprintf(ficlog,"pop_based=%d\n",popbased);
1.126     brouard  10515:     fprintf(ficparo,"pop_based=%d\n",popbased);   
                   10516:     fprintf(ficres,"pop_based=%d\n",popbased);   
                   10517:     
                   10518:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10519:       ungetc(c,ficpar);
                   10520:       fgets(line, MAXLINE, ficpar);
1.141     brouard  10521:       fputs(line,stdout);
1.126     brouard  10522:       fputs(line,ficparo);
                   10523:     }
                   10524:     ungetc(c,ficpar);
                   10525:     
                   10526:     fscanf(ficpar,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj);
                   10527:     fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10528:     printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10529:     fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10530:     fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10531:     /* day and month of proj2 are not used but only year anproj2.*/
                   10532:     
1.217     brouard  10533:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10534:       ungetc(c,ficpar);
                   10535:       fgets(line, MAXLINE, ficpar);
                   10536:       fputs(line,stdout);
                   10537:       fputs(line,ficparo);
                   10538:     }
                   10539:     ungetc(c,ficpar);
                   10540:     
                   10541:     fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);
1.223     brouard  10542:     fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   10543:     fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   10544:     fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
1.217     brouard  10545:     /* day and month of proj2 are not used but only year anproj2.*/
1.126     brouard  10546:     
1.230     brouard  10547:     /* Results */
                   10548:     while(fgets(line, MAXLINE, ficpar)) {
                   10549:       /* If line starts with a # it is a comment */
                   10550:       if (line[0] == '#') {
                   10551:        numlinepar++;
                   10552:        fputs(line,stdout);
                   10553:        fputs(line,ficparo);
                   10554:        fputs(line,ficlog);
                   10555:        continue;
                   10556:       }else
                   10557:        break;
                   10558:     }
                   10559:     while((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   10560:       if (num_filled == 0)
                   10561:        resultline[0]='\0';
                   10562:       else if (num_filled != 1){
                   10563:        printf("ERROR %d: result line should be at minimum 'result=' %s\n",num_filled, line);
                   10564:       }
                   10565:       printf("Result %d: result line should be at minimum 'line=' %s, result=%s\n",num_filled, line, resultline);
                   10566:       decoderesult(resultline);
                   10567:       while(fgets(line, MAXLINE, ficpar)) {
                   10568:        /* If line starts with a # it is a comment */
                   10569:        if (line[0] == '#') {
                   10570:          numlinepar++;
                   10571:          fputs(line,stdout);
                   10572:          fputs(line,ficparo);
                   10573:          fputs(line,ficlog);
                   10574:          continue;
                   10575:        }else
                   10576:          break;
                   10577:       }
                   10578:       if (feof(ficpar))
                   10579:        break;
                   10580:       else{ /* Processess output results for this combination of covariate values */
                   10581:       }                                   
                   10582:     }
                   10583: 
                   10584: 
1.126     brouard  10585:     
1.230     brouard  10586:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  10587:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  10588:     
                   10589:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  10590:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  10591:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  10592: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10593: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  10594:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  10595: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10596: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10597:     }else{
1.218     brouard  10598:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p);
1.220     brouard  10599:     }
                   10600:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.225     brouard  10601:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,prevfcast,backcast, estepm, \
                   10602:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  10603:                
1.225     brouard  10604:     /*------------ free_vector  -------------*/
                   10605:     /*  chdir(path); */
1.220     brouard  10606:                
1.215     brouard  10607:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   10608:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   10609:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   10610:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  10611:     free_lvector(num,1,n);
                   10612:     free_vector(agedc,1,n);
                   10613:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   10614:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   10615:     fclose(ficparo);
                   10616:     fclose(ficres);
1.220     brouard  10617:                
                   10618:                
1.186     brouard  10619:     /* Other results (useful)*/
1.220     brouard  10620:                
                   10621:                
1.126     brouard  10622:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  10623:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   10624:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  10625:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  10626:     fclose(ficrespl);
                   10627: 
                   10628:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  10629:     /*#include "hpijx.h"*/
                   10630:     hPijx(p, bage, fage);
1.145     brouard  10631:     fclose(ficrespij);
1.227     brouard  10632:     
1.220     brouard  10633:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  10634:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  10635:     k=1;
1.126     brouard  10636:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  10637:     
1.219     brouard  10638:     /* Prevalence for each covariates in probs[age][status][cov] */
1.218     brouard  10639:     probs= ma3x(1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.126     brouard  10640:     for(i=1;i<=AGESUP;i++)
1.219     brouard  10641:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  10642:        for(k=1;k<=ncovcombmax;k++)
                   10643:          probs[i][j][k]=0.;
1.219     brouard  10644:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
                   10645:     if (mobilav!=0 ||mobilavproj !=0 ) {
                   10646:       mobaverages= ma3x(1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.227     brouard  10647:       for(i=1;i<=AGESUP;i++)
                   10648:        for(j=1;j<=nlstate;j++)
                   10649:          for(k=1;k<=ncovcombmax;k++)
                   10650:            mobaverages[i][j][k]=0.;
1.219     brouard  10651:       mobaverage=mobaverages;
                   10652:       if (mobilav!=0) {
1.227     brouard  10653:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   10654:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   10655:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   10656:        }
1.219     brouard  10657:       }
                   10658:       /* /\* Prevalence for each covariates in probs[age][status][cov] *\/ */
                   10659:       /* prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   10660:       else if (mobilavproj !=0) {
1.227     brouard  10661:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   10662:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   10663:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   10664:        }
1.219     brouard  10665:       }
                   10666:     }/* end if moving average */
1.227     brouard  10667:     
1.126     brouard  10668:     /*---------- Forecasting ------------------*/
                   10669:     /*if((stepm == 1) && (strcmp(model,".")==0)){*/
                   10670:     if(prevfcast==1){
                   10671:       /*    if(stepm ==1){*/
1.225     brouard  10672:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  10673:     }
1.217     brouard  10674:     if(backcast==1){
1.219     brouard  10675:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   10676:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   10677:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   10678: 
                   10679:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   10680: 
                   10681:       bprlim=matrix(1,nlstate,1,nlstate);
                   10682:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   10683:       fclose(ficresplb);
                   10684: 
1.222     brouard  10685:       hBijx(p, bage, fage, mobaverage);
                   10686:       fclose(ficrespijb);
1.219     brouard  10687:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   10688: 
                   10689:       /* prevbackforecast(fileresu, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, mobilavproj,
1.225     brouard  10690:         bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
1.219     brouard  10691:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   10692:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   10693:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   10694:     }
1.217     brouard  10695:     
1.186     brouard  10696:  
                   10697:     /* ------ Other prevalence ratios------------ */
1.126     brouard  10698: 
1.215     brouard  10699:     free_ivector(wav,1,imx);
                   10700:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   10701:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   10702:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  10703:                
                   10704:                
1.127     brouard  10705:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  10706:                
1.201     brouard  10707:     strcpy(filerese,"E_");
                   10708:     strcat(filerese,fileresu);
1.126     brouard  10709:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   10710:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   10711:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   10712:     }
1.208     brouard  10713:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   10714:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.219     brouard  10715:                
1.227     brouard  10716:     for (k=1; k <= (int) pow(2,cptcoveff); k++){ /* For any combination of dummy covariates, fixed and varying */
1.219     brouard  10717:       fprintf(ficreseij,"\n#****** ");
1.225     brouard  10718:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  10719:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.219     brouard  10720:       }
                   10721:       fprintf(ficreseij,"******\n");
                   10722:       
                   10723:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   10724:       oldm=oldms;savm=savms;
                   10725:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart);  
1.127     brouard  10726:       
1.219     brouard  10727:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  10728:     }
                   10729:     fclose(ficreseij);
1.208     brouard  10730:     printf("done evsij\n");fflush(stdout);
                   10731:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.218     brouard  10732:                
1.227     brouard  10733:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  10734:                
                   10735:                
1.201     brouard  10736:     strcpy(filerest,"T_");
                   10737:     strcat(filerest,fileresu);
1.127     brouard  10738:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   10739:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   10740:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   10741:     }
1.208     brouard  10742:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   10743:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.218     brouard  10744:                
1.126     brouard  10745: 
1.201     brouard  10746:     strcpy(fileresstde,"STDE_");
                   10747:     strcat(fileresstde,fileresu);
1.126     brouard  10748:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  10749:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   10750:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  10751:     }
1.227     brouard  10752:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   10753:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  10754: 
1.201     brouard  10755:     strcpy(filerescve,"CVE_");
                   10756:     strcat(filerescve,fileresu);
1.126     brouard  10757:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  10758:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   10759:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  10760:     }
1.227     brouard  10761:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   10762:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  10763: 
1.201     brouard  10764:     strcpy(fileresv,"V_");
                   10765:     strcat(fileresv,fileresu);
1.126     brouard  10766:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   10767:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   10768:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   10769:     }
1.227     brouard  10770:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   10771:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  10772: 
1.145     brouard  10773:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   10774:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   10775:           
1.225     brouard  10776:     for (k=1; k <= (int) pow(2,cptcoveff); k++){
1.227     brouard  10777:       printf("\n#****** ");
1.208     brouard  10778:       fprintf(ficrest,"\n#****** ");
1.227     brouard  10779:       fprintf(ficlog,"\n#****** ");
                   10780:       for(j=1;j<=cptcoveff;j++){ 
                   10781:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10782:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10783:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10784:       }
1.208     brouard  10785:       fprintf(ficrest,"******\n");
1.227     brouard  10786:       fprintf(ficlog,"******\n");
                   10787:       printf("******\n");
1.208     brouard  10788:       
                   10789:       fprintf(ficresstdeij,"\n#****** ");
                   10790:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  10791:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  10792:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10793:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  10794:       }
                   10795:       fprintf(ficresstdeij,"******\n");
                   10796:       fprintf(ficrescveij,"******\n");
                   10797:       
                   10798:       fprintf(ficresvij,"\n#****** ");
1.225     brouard  10799:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  10800:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  10801:       fprintf(ficresvij,"******\n");
                   10802:       
                   10803:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   10804:       oldm=oldms;savm=savms;
1.227     brouard  10805:       printf(" cvevsij combination#=%d, ",k);
                   10806:       fprintf(ficlog, " cvevsij combination#=%d, ",k);
1.208     brouard  10807:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart);
                   10808:       printf(" end cvevsij \n ");
                   10809:       fprintf(ficlog, " end cvevsij \n ");
                   10810:       
                   10811:       /*
                   10812:        */
                   10813:       /* goto endfree; */
                   10814:       
                   10815:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   10816:       pstamp(ficrest);
                   10817:       
                   10818:       
                   10819:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  10820:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   10821:        cptcod= 0; /* To be deleted */
                   10822:        printf("varevsij vpopbased=%d \n",vpopbased);
                   10823:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
                   10824:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart); /* cptcod not initialized Intel */
                   10825:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   10826:        if(vpopbased==1)
                   10827:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   10828:        else
                   10829:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   10830:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   10831:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   10832:        fprintf(ficrest,"\n");
                   10833:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   10834:        epj=vector(1,nlstate+1);
                   10835:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   10836:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   10837:        for(age=bage; age <=fage ;age++){
                   10838:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k); /*ZZ Is it the correct prevalim */
                   10839:          if (vpopbased==1) {
                   10840:            if(mobilav ==0){
                   10841:              for(i=1; i<=nlstate;i++)
                   10842:                prlim[i][i]=probs[(int)age][i][k];
                   10843:            }else{ /* mobilav */ 
                   10844:              for(i=1; i<=nlstate;i++)
                   10845:                prlim[i][i]=mobaverage[(int)age][i][k];
                   10846:            }
                   10847:          }
1.219     brouard  10848:          
1.227     brouard  10849:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   10850:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   10851:          /* printf(" age %4.0f ",age); */
                   10852:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   10853:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   10854:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   10855:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   10856:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   10857:            }
                   10858:            epj[nlstate+1] +=epj[j];
                   10859:          }
                   10860:          /* printf(" age %4.0f \n",age); */
1.219     brouard  10861:          
1.227     brouard  10862:          for(i=1, vepp=0.;i <=nlstate;i++)
                   10863:            for(j=1;j <=nlstate;j++)
                   10864:              vepp += vareij[i][j][(int)age];
                   10865:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   10866:          for(j=1;j <=nlstate;j++){
                   10867:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   10868:          }
                   10869:          fprintf(ficrest,"\n");
                   10870:        }
1.208     brouard  10871:       } /* End vpopbased */
                   10872:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   10873:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   10874:       free_vector(epj,1,nlstate+1);
                   10875:       printf("done \n");fflush(stdout);
                   10876:       fprintf(ficlog,"done\n");fflush(ficlog);
                   10877:       
1.145     brouard  10878:       /*}*/
1.208     brouard  10879:     } /* End k */
1.227     brouard  10880: 
                   10881:     printf("done State-specific expectancies\n");fflush(stdout);
                   10882:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   10883: 
1.126     brouard  10884:     /*------- Variance of period (stable) prevalence------*/   
1.227     brouard  10885:     
1.201     brouard  10886:     strcpy(fileresvpl,"VPL_");
                   10887:     strcat(fileresvpl,fileresu);
1.126     brouard  10888:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   10889:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   10890:       exit(0);
                   10891:     }
1.208     brouard  10892:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   10893:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.227     brouard  10894:     
1.145     brouard  10895:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   10896:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
1.227     brouard  10897:     
1.225     brouard  10898:     for (k=1; k <= (int) pow(2,cptcoveff); k++){
1.227     brouard  10899:       fprintf(ficresvpl,"\n#****** ");
                   10900:       printf("\n#****** ");
                   10901:       fprintf(ficlog,"\n#****** ");
                   10902:       for(j=1;j<=cptcoveff;j++) {
                   10903:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10904:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10905:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10906:       }
                   10907:       fprintf(ficresvpl,"******\n");
                   10908:       printf("******\n");
                   10909:       fprintf(ficlog,"******\n");
                   10910:       
                   10911:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   10912:       oldm=oldms;savm=savms;
                   10913:       varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, strstart);
                   10914:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
1.145     brouard  10915:       /*}*/
1.126     brouard  10916:     }
1.227     brouard  10917:     
1.126     brouard  10918:     fclose(ficresvpl);
1.208     brouard  10919:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   10920:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
1.227     brouard  10921:     
                   10922:     free_vector(weight,1,n);
                   10923:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   10924:     free_imatrix(s,1,maxwav+1,1,n);
                   10925:     free_matrix(anint,1,maxwav,1,n); 
                   10926:     free_matrix(mint,1,maxwav,1,n);
                   10927:     free_ivector(cod,1,n);
                   10928:     free_ivector(tab,1,NCOVMAX);
                   10929:     fclose(ficresstdeij);
                   10930:     fclose(ficrescveij);
                   10931:     fclose(ficresvij);
                   10932:     fclose(ficrest);
                   10933:     fclose(ficpar);
                   10934:     
                   10935:     
1.126     brouard  10936:     /*---------- End : free ----------------*/
1.219     brouard  10937:     if (mobilav!=0 ||mobilavproj !=0)
                   10938:       free_ma3x(mobaverages,1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
1.218     brouard  10939:     free_ma3x(probs,1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  10940:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   10941:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  10942:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  10943:   /* endfree:*/
                   10944:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   10945:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   10946:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   10947:   free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
1.233     brouard  10948:   free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
1.227     brouard  10949:   free_matrix(coqvar,1,maxwav,1,n);
                   10950:   free_matrix(covar,0,NCOVMAX,1,n);
                   10951:   free_matrix(matcov,1,npar,1,npar);
                   10952:   free_matrix(hess,1,npar,1,npar);
                   10953:   /*free_vector(delti,1,npar);*/
                   10954:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   10955:   free_matrix(agev,1,maxwav,1,imx);
                   10956:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   10957:   
                   10958:   free_ivector(ncodemax,1,NCOVMAX);
                   10959:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   10960:   free_ivector(Dummy,-1,NCOVMAX);
                   10961:   free_ivector(Fixed,-1,NCOVMAX);
                   10962:   free_ivector(Typevar,-1,NCOVMAX);
                   10963:   free_ivector(Tvar,1,NCOVMAX);
1.234   ! brouard  10964:   free_ivector(TvarsQ,1,NCOVMAX);
        !          10965:   free_ivector(TvarsQind,1,NCOVMAX);
        !          10966:   free_ivector(TvarsD,1,NCOVMAX);
        !          10967:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  10968:   free_ivector(TvarFD,1,NCOVMAX);
                   10969:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  10970:   free_ivector(TvarF,1,NCOVMAX);
                   10971:   free_ivector(TvarFind,1,NCOVMAX);
                   10972:   free_ivector(TvarV,1,NCOVMAX);
                   10973:   free_ivector(TvarVind,1,NCOVMAX);
                   10974:   free_ivector(TvarA,1,NCOVMAX);
                   10975:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  10976:   free_ivector(TvarFQ,1,NCOVMAX);
                   10977:   free_ivector(TvarFQind,1,NCOVMAX);
                   10978:   free_ivector(TvarVD,1,NCOVMAX);
                   10979:   free_ivector(TvarVDind,1,NCOVMAX);
                   10980:   free_ivector(TvarVQ,1,NCOVMAX);
                   10981:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  10982:   free_ivector(Tvarsel,1,NCOVMAX);
                   10983:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  10984:   free_ivector(Tposprod,1,NCOVMAX);
                   10985:   free_ivector(Tprod,1,NCOVMAX);
                   10986:   free_ivector(Tvaraff,1,NCOVMAX);
                   10987:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   10988:   free_ivector(Tage,1,NCOVMAX);
                   10989:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  10990:   free_ivector(TmodelInvind,1,NCOVMAX);
                   10991:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  10992:   
                   10993:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   10994:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  10995:   fflush(fichtm);
                   10996:   fflush(ficgp);
                   10997:   
1.227     brouard  10998:   
1.126     brouard  10999:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  11000:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   11001:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  11002:   }else{
                   11003:     printf("End of Imach\n");
                   11004:     fprintf(ficlog,"End of Imach\n");
                   11005:   }
                   11006:   printf("See log file on %s\n",filelog);
                   11007:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  11008:   /*(void) gettimeofday(&end_time,&tzp);*/
                   11009:   rend_time = time(NULL);  
                   11010:   end_time = *localtime(&rend_time);
                   11011:   /* tml = *localtime(&end_time.tm_sec); */
                   11012:   strcpy(strtend,asctime(&end_time));
1.126     brouard  11013:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   11014:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  11015:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  11016:   
1.157     brouard  11017:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   11018:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   11019:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  11020:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   11021: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   11022:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11023:   fclose(fichtm);
                   11024:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11025:   fclose(fichtmcov);
                   11026:   fclose(ficgp);
                   11027:   fclose(ficlog);
                   11028:   /*------ End -----------*/
1.227     brouard  11029:   
                   11030:   
                   11031:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  11032: #ifdef WIN32
1.227     brouard  11033:   if (_chdir(pathcd) != 0)
                   11034:     printf("Can't move to directory %s!\n",path);
                   11035:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  11036: #else
1.227     brouard  11037:     if(chdir(pathcd) != 0)
                   11038:       printf("Can't move to directory %s!\n", path);
                   11039:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  11040: #endif 
1.126     brouard  11041:     printf("Current directory %s!\n",pathcd);
                   11042:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   11043:   sprintf(plotcmd,"gnuplot");
1.157     brouard  11044: #ifdef _WIN32
1.126     brouard  11045:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   11046: #endif
                   11047:   if(!stat(plotcmd,&info)){
1.158     brouard  11048:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11049:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  11050:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  11051:     }else
                   11052:       strcpy(pplotcmd,plotcmd);
1.157     brouard  11053: #ifdef __unix
1.126     brouard  11054:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   11055:     if(!stat(plotcmd,&info)){
1.158     brouard  11056:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11057:     }else
                   11058:       strcpy(pplotcmd,plotcmd);
                   11059: #endif
                   11060:   }else
                   11061:     strcpy(pplotcmd,plotcmd);
                   11062:   
                   11063:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  11064:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  11065:   
1.126     brouard  11066:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  11067:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  11068:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  11069:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  11070:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  11071:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  11072:   }
1.158     brouard  11073:   printf(" Successful, please wait...");
1.126     brouard  11074:   while (z[0] != 'q') {
                   11075:     /* chdir(path); */
1.154     brouard  11076:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  11077:     scanf("%s",z);
                   11078: /*     if (z[0] == 'c') system("./imach"); */
                   11079:     if (z[0] == 'e') {
1.158     brouard  11080: #ifdef __APPLE__
1.152     brouard  11081:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  11082: #elif __linux
                   11083:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  11084: #else
1.152     brouard  11085:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  11086: #endif
                   11087:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   11088:       system(pplotcmd);
1.126     brouard  11089:     }
                   11090:     else if (z[0] == 'g') system(plotcmd);
                   11091:     else if (z[0] == 'q') exit(0);
                   11092:   }
1.227     brouard  11093: end:
1.126     brouard  11094:   while (z[0] != 'q') {
1.195     brouard  11095:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  11096:     scanf("%s",z);
                   11097:   }
                   11098: }

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