Annotation of imach/src/imach.c, revision 1.244

1.244   ! brouard     1: /* $Id: imach.c,v 1.243 2016/09/02 06:45:35 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.244   ! brouard     4:   Revision 1.243  2016/09/02 06:45:35  brouard
        !             5:   *** empty log message ***
        !             6: 
1.243     brouard     7:   Revision 1.242  2016/08/30 15:01:20  brouard
                      8:   Summary: Fixing a lots
                      9: 
1.242     brouard    10:   Revision 1.241  2016/08/29 17:17:25  brouard
                     11:   Summary: gnuplot problem in Back projection to fix
                     12: 
1.241     brouard    13:   Revision 1.240  2016/08/29 07:53:18  brouard
                     14:   Summary: Better
                     15: 
1.240     brouard    16:   Revision 1.239  2016/08/26 15:51:03  brouard
                     17:   Summary: Improvement in Powell output in order to copy and paste
                     18: 
                     19:   Author:
                     20: 
1.239     brouard    21:   Revision 1.238  2016/08/26 14:23:35  brouard
                     22:   Summary: Starting tests of 0.99
                     23: 
1.238     brouard    24:   Revision 1.237  2016/08/26 09:20:19  brouard
                     25:   Summary: to valgrind
                     26: 
1.237     brouard    27:   Revision 1.236  2016/08/25 10:50:18  brouard
                     28:   *** empty log message ***
                     29: 
1.236     brouard    30:   Revision 1.235  2016/08/25 06:59:23  brouard
                     31:   *** empty log message ***
                     32: 
1.235     brouard    33:   Revision 1.234  2016/08/23 16:51:20  brouard
                     34:   *** empty log message ***
                     35: 
1.234     brouard    36:   Revision 1.233  2016/08/23 07:40:50  brouard
                     37:   Summary: not working
                     38: 
1.233     brouard    39:   Revision 1.232  2016/08/22 14:20:21  brouard
                     40:   Summary: not working
                     41: 
1.232     brouard    42:   Revision 1.231  2016/08/22 07:17:15  brouard
                     43:   Summary: not working
                     44: 
1.231     brouard    45:   Revision 1.230  2016/08/22 06:55:53  brouard
                     46:   Summary: Not working
                     47: 
1.230     brouard    48:   Revision 1.229  2016/07/23 09:45:53  brouard
                     49:   Summary: Completing for func too
                     50: 
1.229     brouard    51:   Revision 1.228  2016/07/22 17:45:30  brouard
                     52:   Summary: Fixing some arrays, still debugging
                     53: 
1.227     brouard    54:   Revision 1.226  2016/07/12 18:42:34  brouard
                     55:   Summary: temp
                     56: 
1.226     brouard    57:   Revision 1.225  2016/07/12 08:40:03  brouard
                     58:   Summary: saving but not running
                     59: 
1.225     brouard    60:   Revision 1.224  2016/07/01 13:16:01  brouard
                     61:   Summary: Fixes
                     62: 
1.224     brouard    63:   Revision 1.223  2016/02/19 09:23:35  brouard
                     64:   Summary: temporary
                     65: 
1.223     brouard    66:   Revision 1.222  2016/02/17 08:14:50  brouard
                     67:   Summary: Probably last 0.98 stable version 0.98r6
                     68: 
1.222     brouard    69:   Revision 1.221  2016/02/15 23:35:36  brouard
                     70:   Summary: minor bug
                     71: 
1.220     brouard    72:   Revision 1.219  2016/02/15 00:48:12  brouard
                     73:   *** empty log message ***
                     74: 
1.219     brouard    75:   Revision 1.218  2016/02/12 11:29:23  brouard
                     76:   Summary: 0.99 Back projections
                     77: 
1.218     brouard    78:   Revision 1.217  2015/12/23 17:18:31  brouard
                     79:   Summary: Experimental backcast
                     80: 
1.217     brouard    81:   Revision 1.216  2015/12/18 17:32:11  brouard
                     82:   Summary: 0.98r4 Warning and status=-2
                     83: 
                     84:   Version 0.98r4 is now:
                     85:    - displaying an error when status is -1, date of interview unknown and date of death known;
                     86:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                     87:   Older changes concerning s=-2, dating from 2005 have been supersed.
                     88: 
1.216     brouard    89:   Revision 1.215  2015/12/16 08:52:24  brouard
                     90:   Summary: 0.98r4 working
                     91: 
1.215     brouard    92:   Revision 1.214  2015/12/16 06:57:54  brouard
                     93:   Summary: temporary not working
                     94: 
1.214     brouard    95:   Revision 1.213  2015/12/11 18:22:17  brouard
                     96:   Summary: 0.98r4
                     97: 
1.213     brouard    98:   Revision 1.212  2015/11/21 12:47:24  brouard
                     99:   Summary: minor typo
                    100: 
1.212     brouard   101:   Revision 1.211  2015/11/21 12:41:11  brouard
                    102:   Summary: 0.98r3 with some graph of projected cross-sectional
                    103: 
                    104:   Author: Nicolas Brouard
                    105: 
1.211     brouard   106:   Revision 1.210  2015/11/18 17:41:20  brouard
                    107:   Summary: Start working on projected prevalences
                    108: 
1.210     brouard   109:   Revision 1.209  2015/11/17 22:12:03  brouard
                    110:   Summary: Adding ftolpl parameter
                    111:   Author: N Brouard
                    112: 
                    113:   We had difficulties to get smoothed confidence intervals. It was due
                    114:   to the period prevalence which wasn't computed accurately. The inner
                    115:   parameter ftolpl is now an outer parameter of the .imach parameter
                    116:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    117:   computation are long.
                    118: 
1.209     brouard   119:   Revision 1.208  2015/11/17 14:31:57  brouard
                    120:   Summary: temporary
                    121: 
1.208     brouard   122:   Revision 1.207  2015/10/27 17:36:57  brouard
                    123:   *** empty log message ***
                    124: 
1.207     brouard   125:   Revision 1.206  2015/10/24 07:14:11  brouard
                    126:   *** empty log message ***
                    127: 
1.206     brouard   128:   Revision 1.205  2015/10/23 15:50:53  brouard
                    129:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    130: 
1.205     brouard   131:   Revision 1.204  2015/10/01 16:20:26  brouard
                    132:   Summary: Some new graphs of contribution to likelihood
                    133: 
1.204     brouard   134:   Revision 1.203  2015/09/30 17:45:14  brouard
                    135:   Summary: looking at better estimation of the hessian
                    136: 
                    137:   Also a better criteria for convergence to the period prevalence And
                    138:   therefore adding the number of years needed to converge. (The
                    139:   prevalence in any alive state shold sum to one
                    140: 
1.203     brouard   141:   Revision 1.202  2015/09/22 19:45:16  brouard
                    142:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    143: 
1.202     brouard   144:   Revision 1.201  2015/09/15 17:34:58  brouard
                    145:   Summary: 0.98r0
                    146: 
                    147:   - Some new graphs like suvival functions
                    148:   - Some bugs fixed like model=1+age+V2.
                    149: 
1.201     brouard   150:   Revision 1.200  2015/09/09 16:53:55  brouard
                    151:   Summary: Big bug thanks to Flavia
                    152: 
                    153:   Even model=1+age+V2. did not work anymore
                    154: 
1.200     brouard   155:   Revision 1.199  2015/09/07 14:09:23  brouard
                    156:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    157: 
1.199     brouard   158:   Revision 1.198  2015/09/03 07:14:39  brouard
                    159:   Summary: 0.98q5 Flavia
                    160: 
1.198     brouard   161:   Revision 1.197  2015/09/01 18:24:39  brouard
                    162:   *** empty log message ***
                    163: 
1.197     brouard   164:   Revision 1.196  2015/08/18 23:17:52  brouard
                    165:   Summary: 0.98q5
                    166: 
1.196     brouard   167:   Revision 1.195  2015/08/18 16:28:39  brouard
                    168:   Summary: Adding a hack for testing purpose
                    169: 
                    170:   After reading the title, ftol and model lines, if the comment line has
                    171:   a q, starting with #q, the answer at the end of the run is quit. It
                    172:   permits to run test files in batch with ctest. The former workaround was
                    173:   $ echo q | imach foo.imach
                    174: 
1.195     brouard   175:   Revision 1.194  2015/08/18 13:32:00  brouard
                    176:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    177: 
1.194     brouard   178:   Revision 1.193  2015/08/04 07:17:42  brouard
                    179:   Summary: 0.98q4
                    180: 
1.193     brouard   181:   Revision 1.192  2015/07/16 16:49:02  brouard
                    182:   Summary: Fixing some outputs
                    183: 
1.192     brouard   184:   Revision 1.191  2015/07/14 10:00:33  brouard
                    185:   Summary: Some fixes
                    186: 
1.191     brouard   187:   Revision 1.190  2015/05/05 08:51:13  brouard
                    188:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    189: 
                    190:   Fix 1+age+.
                    191: 
1.190     brouard   192:   Revision 1.189  2015/04/30 14:45:16  brouard
                    193:   Summary: 0.98q2
                    194: 
1.189     brouard   195:   Revision 1.188  2015/04/30 08:27:53  brouard
                    196:   *** empty log message ***
                    197: 
1.188     brouard   198:   Revision 1.187  2015/04/29 09:11:15  brouard
                    199:   *** empty log message ***
                    200: 
1.187     brouard   201:   Revision 1.186  2015/04/23 12:01:52  brouard
                    202:   Summary: V1*age is working now, version 0.98q1
                    203: 
                    204:   Some codes had been disabled in order to simplify and Vn*age was
                    205:   working in the optimization phase, ie, giving correct MLE parameters,
                    206:   but, as usual, outputs were not correct and program core dumped.
                    207: 
1.186     brouard   208:   Revision 1.185  2015/03/11 13:26:42  brouard
                    209:   Summary: Inclusion of compile and links command line for Intel Compiler
                    210: 
1.185     brouard   211:   Revision 1.184  2015/03/11 11:52:39  brouard
                    212:   Summary: Back from Windows 8. Intel Compiler
                    213: 
1.184     brouard   214:   Revision 1.183  2015/03/10 20:34:32  brouard
                    215:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    216: 
                    217:   We use directest instead of original Powell test; probably no
                    218:   incidence on the results, but better justifications;
                    219:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    220:   wrong results.
                    221: 
1.183     brouard   222:   Revision 1.182  2015/02/12 08:19:57  brouard
                    223:   Summary: Trying to keep directest which seems simpler and more general
                    224:   Author: Nicolas Brouard
                    225: 
1.182     brouard   226:   Revision 1.181  2015/02/11 23:22:24  brouard
                    227:   Summary: Comments on Powell added
                    228: 
                    229:   Author:
                    230: 
1.181     brouard   231:   Revision 1.180  2015/02/11 17:33:45  brouard
                    232:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    233: 
1.180     brouard   234:   Revision 1.179  2015/01/04 09:57:06  brouard
                    235:   Summary: back to OS/X
                    236: 
1.179     brouard   237:   Revision 1.178  2015/01/04 09:35:48  brouard
                    238:   *** empty log message ***
                    239: 
1.178     brouard   240:   Revision 1.177  2015/01/03 18:40:56  brouard
                    241:   Summary: Still testing ilc32 on OSX
                    242: 
1.177     brouard   243:   Revision 1.176  2015/01/03 16:45:04  brouard
                    244:   *** empty log message ***
                    245: 
1.176     brouard   246:   Revision 1.175  2015/01/03 16:33:42  brouard
                    247:   *** empty log message ***
                    248: 
1.175     brouard   249:   Revision 1.174  2015/01/03 16:15:49  brouard
                    250:   Summary: Still in cross-compilation
                    251: 
1.174     brouard   252:   Revision 1.173  2015/01/03 12:06:26  brouard
                    253:   Summary: trying to detect cross-compilation
                    254: 
1.173     brouard   255:   Revision 1.172  2014/12/27 12:07:47  brouard
                    256:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    257: 
1.172     brouard   258:   Revision 1.171  2014/12/23 13:26:59  brouard
                    259:   Summary: Back from Visual C
                    260: 
                    261:   Still problem with utsname.h on Windows
                    262: 
1.171     brouard   263:   Revision 1.170  2014/12/23 11:17:12  brouard
                    264:   Summary: Cleaning some \%% back to %%
                    265: 
                    266:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    267: 
1.170     brouard   268:   Revision 1.169  2014/12/22 23:08:31  brouard
                    269:   Summary: 0.98p
                    270: 
                    271:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    272: 
1.169     brouard   273:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   274:   Summary: update
1.169     brouard   275: 
1.168     brouard   276:   Revision 1.167  2014/12/22 13:50:56  brouard
                    277:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    278: 
                    279:   Testing on Linux 64
                    280: 
1.167     brouard   281:   Revision 1.166  2014/12/22 11:40:47  brouard
                    282:   *** empty log message ***
                    283: 
1.166     brouard   284:   Revision 1.165  2014/12/16 11:20:36  brouard
                    285:   Summary: After compiling on Visual C
                    286: 
                    287:   * imach.c (Module): Merging 1.61 to 1.162
                    288: 
1.165     brouard   289:   Revision 1.164  2014/12/16 10:52:11  brouard
                    290:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    291: 
                    292:   * imach.c (Module): Merging 1.61 to 1.162
                    293: 
1.164     brouard   294:   Revision 1.163  2014/12/16 10:30:11  brouard
                    295:   * imach.c (Module): Merging 1.61 to 1.162
                    296: 
1.163     brouard   297:   Revision 1.162  2014/09/25 11:43:39  brouard
                    298:   Summary: temporary backup 0.99!
                    299: 
1.162     brouard   300:   Revision 1.1  2014/09/16 11:06:58  brouard
                    301:   Summary: With some code (wrong) for nlopt
                    302: 
                    303:   Author:
                    304: 
                    305:   Revision 1.161  2014/09/15 20:41:41  brouard
                    306:   Summary: Problem with macro SQR on Intel compiler
                    307: 
1.161     brouard   308:   Revision 1.160  2014/09/02 09:24:05  brouard
                    309:   *** empty log message ***
                    310: 
1.160     brouard   311:   Revision 1.159  2014/09/01 10:34:10  brouard
                    312:   Summary: WIN32
                    313:   Author: Brouard
                    314: 
1.159     brouard   315:   Revision 1.158  2014/08/27 17:11:51  brouard
                    316:   *** empty log message ***
                    317: 
1.158     brouard   318:   Revision 1.157  2014/08/27 16:26:55  brouard
                    319:   Summary: Preparing windows Visual studio version
                    320:   Author: Brouard
                    321: 
                    322:   In order to compile on Visual studio, time.h is now correct and time_t
                    323:   and tm struct should be used. difftime should be used but sometimes I
                    324:   just make the differences in raw time format (time(&now).
                    325:   Trying to suppress #ifdef LINUX
                    326:   Add xdg-open for __linux in order to open default browser.
                    327: 
1.157     brouard   328:   Revision 1.156  2014/08/25 20:10:10  brouard
                    329:   *** empty log message ***
                    330: 
1.156     brouard   331:   Revision 1.155  2014/08/25 18:32:34  brouard
                    332:   Summary: New compile, minor changes
                    333:   Author: Brouard
                    334: 
1.155     brouard   335:   Revision 1.154  2014/06/20 17:32:08  brouard
                    336:   Summary: Outputs now all graphs of convergence to period prevalence
                    337: 
1.154     brouard   338:   Revision 1.153  2014/06/20 16:45:46  brouard
                    339:   Summary: If 3 live state, convergence to period prevalence on same graph
                    340:   Author: Brouard
                    341: 
1.153     brouard   342:   Revision 1.152  2014/06/18 17:54:09  brouard
                    343:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    344: 
1.152     brouard   345:   Revision 1.151  2014/06/18 16:43:30  brouard
                    346:   *** empty log message ***
                    347: 
1.151     brouard   348:   Revision 1.150  2014/06/18 16:42:35  brouard
                    349:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    350:   Author: brouard
                    351: 
1.150     brouard   352:   Revision 1.149  2014/06/18 15:51:14  brouard
                    353:   Summary: Some fixes in parameter files errors
                    354:   Author: Nicolas Brouard
                    355: 
1.149     brouard   356:   Revision 1.148  2014/06/17 17:38:48  brouard
                    357:   Summary: Nothing new
                    358:   Author: Brouard
                    359: 
                    360:   Just a new packaging for OS/X version 0.98nS
                    361: 
1.148     brouard   362:   Revision 1.147  2014/06/16 10:33:11  brouard
                    363:   *** empty log message ***
                    364: 
1.147     brouard   365:   Revision 1.146  2014/06/16 10:20:28  brouard
                    366:   Summary: Merge
                    367:   Author: Brouard
                    368: 
                    369:   Merge, before building revised version.
                    370: 
1.146     brouard   371:   Revision 1.145  2014/06/10 21:23:15  brouard
                    372:   Summary: Debugging with valgrind
                    373:   Author: Nicolas Brouard
                    374: 
                    375:   Lot of changes in order to output the results with some covariates
                    376:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    377:   improve the code.
                    378:   No more memory valgrind error but a lot has to be done in order to
                    379:   continue the work of splitting the code into subroutines.
                    380:   Also, decodemodel has been improved. Tricode is still not
                    381:   optimal. nbcode should be improved. Documentation has been added in
                    382:   the source code.
                    383: 
1.144     brouard   384:   Revision 1.143  2014/01/26 09:45:38  brouard
                    385:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    386: 
                    387:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    388:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    389: 
1.143     brouard   390:   Revision 1.142  2014/01/26 03:57:36  brouard
                    391:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    392: 
                    393:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    394: 
1.142     brouard   395:   Revision 1.141  2014/01/26 02:42:01  brouard
                    396:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    397: 
1.141     brouard   398:   Revision 1.140  2011/09/02 10:37:54  brouard
                    399:   Summary: times.h is ok with mingw32 now.
                    400: 
1.140     brouard   401:   Revision 1.139  2010/06/14 07:50:17  brouard
                    402:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    403:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    404: 
1.139     brouard   405:   Revision 1.138  2010/04/30 18:19:40  brouard
                    406:   *** empty log message ***
                    407: 
1.138     brouard   408:   Revision 1.137  2010/04/29 18:11:38  brouard
                    409:   (Module): Checking covariates for more complex models
                    410:   than V1+V2. A lot of change to be done. Unstable.
                    411: 
1.137     brouard   412:   Revision 1.136  2010/04/26 20:30:53  brouard
                    413:   (Module): merging some libgsl code. Fixing computation
                    414:   of likelione (using inter/intrapolation if mle = 0) in order to
                    415:   get same likelihood as if mle=1.
                    416:   Some cleaning of code and comments added.
                    417: 
1.136     brouard   418:   Revision 1.135  2009/10/29 15:33:14  brouard
                    419:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    420: 
1.135     brouard   421:   Revision 1.134  2009/10/29 13:18:53  brouard
                    422:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    423: 
1.134     brouard   424:   Revision 1.133  2009/07/06 10:21:25  brouard
                    425:   just nforces
                    426: 
1.133     brouard   427:   Revision 1.132  2009/07/06 08:22:05  brouard
                    428:   Many tings
                    429: 
1.132     brouard   430:   Revision 1.131  2009/06/20 16:22:47  brouard
                    431:   Some dimensions resccaled
                    432: 
1.131     brouard   433:   Revision 1.130  2009/05/26 06:44:34  brouard
                    434:   (Module): Max Covariate is now set to 20 instead of 8. A
                    435:   lot of cleaning with variables initialized to 0. Trying to make
                    436:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    437: 
1.130     brouard   438:   Revision 1.129  2007/08/31 13:49:27  lievre
                    439:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    440: 
1.129     lievre    441:   Revision 1.128  2006/06/30 13:02:05  brouard
                    442:   (Module): Clarifications on computing e.j
                    443: 
1.128     brouard   444:   Revision 1.127  2006/04/28 18:11:50  brouard
                    445:   (Module): Yes the sum of survivors was wrong since
                    446:   imach-114 because nhstepm was no more computed in the age
                    447:   loop. Now we define nhstepma in the age loop.
                    448:   (Module): In order to speed up (in case of numerous covariates) we
                    449:   compute health expectancies (without variances) in a first step
                    450:   and then all the health expectancies with variances or standard
                    451:   deviation (needs data from the Hessian matrices) which slows the
                    452:   computation.
                    453:   In the future we should be able to stop the program is only health
                    454:   expectancies and graph are needed without standard deviations.
                    455: 
1.127     brouard   456:   Revision 1.126  2006/04/28 17:23:28  brouard
                    457:   (Module): Yes the sum of survivors was wrong since
                    458:   imach-114 because nhstepm was no more computed in the age
                    459:   loop. Now we define nhstepma in the age loop.
                    460:   Version 0.98h
                    461: 
1.126     brouard   462:   Revision 1.125  2006/04/04 15:20:31  lievre
                    463:   Errors in calculation of health expectancies. Age was not initialized.
                    464:   Forecasting file added.
                    465: 
                    466:   Revision 1.124  2006/03/22 17:13:53  lievre
                    467:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    468:   The log-likelihood is printed in the log file
                    469: 
                    470:   Revision 1.123  2006/03/20 10:52:43  brouard
                    471:   * imach.c (Module): <title> changed, corresponds to .htm file
                    472:   name. <head> headers where missing.
                    473: 
                    474:   * imach.c (Module): Weights can have a decimal point as for
                    475:   English (a comma might work with a correct LC_NUMERIC environment,
                    476:   otherwise the weight is truncated).
                    477:   Modification of warning when the covariates values are not 0 or
                    478:   1.
                    479:   Version 0.98g
                    480: 
                    481:   Revision 1.122  2006/03/20 09:45:41  brouard
                    482:   (Module): Weights can have a decimal point as for
                    483:   English (a comma might work with a correct LC_NUMERIC environment,
                    484:   otherwise the weight is truncated).
                    485:   Modification of warning when the covariates values are not 0 or
                    486:   1.
                    487:   Version 0.98g
                    488: 
                    489:   Revision 1.121  2006/03/16 17:45:01  lievre
                    490:   * imach.c (Module): Comments concerning covariates added
                    491: 
                    492:   * imach.c (Module): refinements in the computation of lli if
                    493:   status=-2 in order to have more reliable computation if stepm is
                    494:   not 1 month. Version 0.98f
                    495: 
                    496:   Revision 1.120  2006/03/16 15:10:38  lievre
                    497:   (Module): refinements in the computation of lli if
                    498:   status=-2 in order to have more reliable computation if stepm is
                    499:   not 1 month. Version 0.98f
                    500: 
                    501:   Revision 1.119  2006/03/15 17:42:26  brouard
                    502:   (Module): Bug if status = -2, the loglikelihood was
                    503:   computed as likelihood omitting the logarithm. Version O.98e
                    504: 
                    505:   Revision 1.118  2006/03/14 18:20:07  brouard
                    506:   (Module): varevsij Comments added explaining the second
                    507:   table of variances if popbased=1 .
                    508:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    509:   (Module): Function pstamp added
                    510:   (Module): Version 0.98d
                    511: 
                    512:   Revision 1.117  2006/03/14 17:16:22  brouard
                    513:   (Module): varevsij Comments added explaining the second
                    514:   table of variances if popbased=1 .
                    515:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    516:   (Module): Function pstamp added
                    517:   (Module): Version 0.98d
                    518: 
                    519:   Revision 1.116  2006/03/06 10:29:27  brouard
                    520:   (Module): Variance-covariance wrong links and
                    521:   varian-covariance of ej. is needed (Saito).
                    522: 
                    523:   Revision 1.115  2006/02/27 12:17:45  brouard
                    524:   (Module): One freematrix added in mlikeli! 0.98c
                    525: 
                    526:   Revision 1.114  2006/02/26 12:57:58  brouard
                    527:   (Module): Some improvements in processing parameter
                    528:   filename with strsep.
                    529: 
                    530:   Revision 1.113  2006/02/24 14:20:24  brouard
                    531:   (Module): Memory leaks checks with valgrind and:
                    532:   datafile was not closed, some imatrix were not freed and on matrix
                    533:   allocation too.
                    534: 
                    535:   Revision 1.112  2006/01/30 09:55:26  brouard
                    536:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    537: 
                    538:   Revision 1.111  2006/01/25 20:38:18  brouard
                    539:   (Module): Lots of cleaning and bugs added (Gompertz)
                    540:   (Module): Comments can be added in data file. Missing date values
                    541:   can be a simple dot '.'.
                    542: 
                    543:   Revision 1.110  2006/01/25 00:51:50  brouard
                    544:   (Module): Lots of cleaning and bugs added (Gompertz)
                    545: 
                    546:   Revision 1.109  2006/01/24 19:37:15  brouard
                    547:   (Module): Comments (lines starting with a #) are allowed in data.
                    548: 
                    549:   Revision 1.108  2006/01/19 18:05:42  lievre
                    550:   Gnuplot problem appeared...
                    551:   To be fixed
                    552: 
                    553:   Revision 1.107  2006/01/19 16:20:37  brouard
                    554:   Test existence of gnuplot in imach path
                    555: 
                    556:   Revision 1.106  2006/01/19 13:24:36  brouard
                    557:   Some cleaning and links added in html output
                    558: 
                    559:   Revision 1.105  2006/01/05 20:23:19  lievre
                    560:   *** empty log message ***
                    561: 
                    562:   Revision 1.104  2005/09/30 16:11:43  lievre
                    563:   (Module): sump fixed, loop imx fixed, and simplifications.
                    564:   (Module): If the status is missing at the last wave but we know
                    565:   that the person is alive, then we can code his/her status as -2
                    566:   (instead of missing=-1 in earlier versions) and his/her
                    567:   contributions to the likelihood is 1 - Prob of dying from last
                    568:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    569:   the healthy state at last known wave). Version is 0.98
                    570: 
                    571:   Revision 1.103  2005/09/30 15:54:49  lievre
                    572:   (Module): sump fixed, loop imx fixed, and simplifications.
                    573: 
                    574:   Revision 1.102  2004/09/15 17:31:30  brouard
                    575:   Add the possibility to read data file including tab characters.
                    576: 
                    577:   Revision 1.101  2004/09/15 10:38:38  brouard
                    578:   Fix on curr_time
                    579: 
                    580:   Revision 1.100  2004/07/12 18:29:06  brouard
                    581:   Add version for Mac OS X. Just define UNIX in Makefile
                    582: 
                    583:   Revision 1.99  2004/06/05 08:57:40  brouard
                    584:   *** empty log message ***
                    585: 
                    586:   Revision 1.98  2004/05/16 15:05:56  brouard
                    587:   New version 0.97 . First attempt to estimate force of mortality
                    588:   directly from the data i.e. without the need of knowing the health
                    589:   state at each age, but using a Gompertz model: log u =a + b*age .
                    590:   This is the basic analysis of mortality and should be done before any
                    591:   other analysis, in order to test if the mortality estimated from the
                    592:   cross-longitudinal survey is different from the mortality estimated
                    593:   from other sources like vital statistic data.
                    594: 
                    595:   The same imach parameter file can be used but the option for mle should be -3.
                    596: 
1.133     brouard   597:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   598:   former routines in order to include the new code within the former code.
                    599: 
                    600:   The output is very simple: only an estimate of the intercept and of
                    601:   the slope with 95% confident intervals.
                    602: 
                    603:   Current limitations:
                    604:   A) Even if you enter covariates, i.e. with the
                    605:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    606:   B) There is no computation of Life Expectancy nor Life Table.
                    607: 
                    608:   Revision 1.97  2004/02/20 13:25:42  lievre
                    609:   Version 0.96d. Population forecasting command line is (temporarily)
                    610:   suppressed.
                    611: 
                    612:   Revision 1.96  2003/07/15 15:38:55  brouard
                    613:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    614:   rewritten within the same printf. Workaround: many printfs.
                    615: 
                    616:   Revision 1.95  2003/07/08 07:54:34  brouard
                    617:   * imach.c (Repository):
                    618:   (Repository): Using imachwizard code to output a more meaningful covariance
                    619:   matrix (cov(a12,c31) instead of numbers.
                    620: 
                    621:   Revision 1.94  2003/06/27 13:00:02  brouard
                    622:   Just cleaning
                    623: 
                    624:   Revision 1.93  2003/06/25 16:33:55  brouard
                    625:   (Module): On windows (cygwin) function asctime_r doesn't
                    626:   exist so I changed back to asctime which exists.
                    627:   (Module): Version 0.96b
                    628: 
                    629:   Revision 1.92  2003/06/25 16:30:45  brouard
                    630:   (Module): On windows (cygwin) function asctime_r doesn't
                    631:   exist so I changed back to asctime which exists.
                    632: 
                    633:   Revision 1.91  2003/06/25 15:30:29  brouard
                    634:   * imach.c (Repository): Duplicated warning errors corrected.
                    635:   (Repository): Elapsed time after each iteration is now output. It
                    636:   helps to forecast when convergence will be reached. Elapsed time
                    637:   is stamped in powell.  We created a new html file for the graphs
                    638:   concerning matrix of covariance. It has extension -cov.htm.
                    639: 
                    640:   Revision 1.90  2003/06/24 12:34:15  brouard
                    641:   (Module): Some bugs corrected for windows. Also, when
                    642:   mle=-1 a template is output in file "or"mypar.txt with the design
                    643:   of the covariance matrix to be input.
                    644: 
                    645:   Revision 1.89  2003/06/24 12:30:52  brouard
                    646:   (Module): Some bugs corrected for windows. Also, when
                    647:   mle=-1 a template is output in file "or"mypar.txt with the design
                    648:   of the covariance matrix to be input.
                    649: 
                    650:   Revision 1.88  2003/06/23 17:54:56  brouard
                    651:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    652: 
                    653:   Revision 1.87  2003/06/18 12:26:01  brouard
                    654:   Version 0.96
                    655: 
                    656:   Revision 1.86  2003/06/17 20:04:08  brouard
                    657:   (Module): Change position of html and gnuplot routines and added
                    658:   routine fileappend.
                    659: 
                    660:   Revision 1.85  2003/06/17 13:12:43  brouard
                    661:   * imach.c (Repository): Check when date of death was earlier that
                    662:   current date of interview. It may happen when the death was just
                    663:   prior to the death. In this case, dh was negative and likelihood
                    664:   was wrong (infinity). We still send an "Error" but patch by
                    665:   assuming that the date of death was just one stepm after the
                    666:   interview.
                    667:   (Repository): Because some people have very long ID (first column)
                    668:   we changed int to long in num[] and we added a new lvector for
                    669:   memory allocation. But we also truncated to 8 characters (left
                    670:   truncation)
                    671:   (Repository): No more line truncation errors.
                    672: 
                    673:   Revision 1.84  2003/06/13 21:44:43  brouard
                    674:   * imach.c (Repository): Replace "freqsummary" at a correct
                    675:   place. It differs from routine "prevalence" which may be called
                    676:   many times. Probs is memory consuming and must be used with
                    677:   parcimony.
                    678:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    679: 
                    680:   Revision 1.83  2003/06/10 13:39:11  lievre
                    681:   *** empty log message ***
                    682: 
                    683:   Revision 1.82  2003/06/05 15:57:20  brouard
                    684:   Add log in  imach.c and  fullversion number is now printed.
                    685: 
                    686: */
                    687: /*
                    688:    Interpolated Markov Chain
                    689: 
                    690:   Short summary of the programme:
                    691:   
1.227     brouard   692:   This program computes Healthy Life Expectancies or State-specific
                    693:   (if states aren't health statuses) Expectancies from
                    694:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    695: 
                    696:   -1- a first survey ("cross") where individuals from different ages
                    697:   are interviewed on their health status or degree of disability (in
                    698:   the case of a health survey which is our main interest)
                    699: 
                    700:   -2- at least a second wave of interviews ("longitudinal") which
                    701:   measure each change (if any) in individual health status.  Health
                    702:   expectancies are computed from the time spent in each health state
                    703:   according to a model. More health states you consider, more time is
                    704:   necessary to reach the Maximum Likelihood of the parameters involved
                    705:   in the model.  The simplest model is the multinomial logistic model
                    706:   where pij is the probability to be observed in state j at the second
                    707:   wave conditional to be observed in state i at the first
                    708:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    709:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    710:   have a more complex model than "constant and age", you should modify
                    711:   the program where the markup *Covariates have to be included here
                    712:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   713:   convergence.
                    714: 
                    715:   The advantage of this computer programme, compared to a simple
                    716:   multinomial logistic model, is clear when the delay between waves is not
                    717:   identical for each individual. Also, if a individual missed an
                    718:   intermediate interview, the information is lost, but taken into
                    719:   account using an interpolation or extrapolation.  
                    720: 
                    721:   hPijx is the probability to be observed in state i at age x+h
                    722:   conditional to the observed state i at age x. The delay 'h' can be
                    723:   split into an exact number (nh*stepm) of unobserved intermediate
                    724:   states. This elementary transition (by month, quarter,
                    725:   semester or year) is modelled as a multinomial logistic.  The hPx
                    726:   matrix is simply the matrix product of nh*stepm elementary matrices
                    727:   and the contribution of each individual to the likelihood is simply
                    728:   hPijx.
                    729: 
                    730:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   731:   of the life expectancies. It also computes the period (stable) prevalence.
                    732: 
                    733: Back prevalence and projections:
1.227     brouard   734: 
                    735:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    736:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    737:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    738:    mobilavproj)
                    739: 
                    740:     Computes the back prevalence limit for any combination of
                    741:     covariate values k at any age between ageminpar and agemaxpar and
                    742:     returns it in **bprlim. In the loops,
                    743: 
                    744:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    745:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    746: 
                    747:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   748:    Computes for any combination of covariates k and any age between bage and fage 
                    749:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    750:                        oldm=oldms;savm=savms;
1.227     brouard   751: 
                    752:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);
1.218     brouard   753:      Computes the transition matrix starting at age 'age' over
                    754:      'nhstepm*hstepm*stepm' months (i.e. until
                    755:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   756:      nhstepm*hstepm matrices. 
                    757: 
                    758:      Returns p3mat[i][j][h] after calling
                    759:      p3mat[i][j][h]=matprod2(newm,
                    760:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    761:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    762:      oldm);
1.226     brouard   763: 
                    764: Important routines
                    765: 
                    766: - func (or funcone), computes logit (pij) distinguishing
                    767:   o fixed variables (single or product dummies or quantitative);
                    768:   o varying variables by:
                    769:    (1) wave (single, product dummies, quantitative), 
                    770:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    771:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    772:        % varying dummy (not done) or quantitative (not done);
                    773: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    774:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    775: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    776:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    777:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   778: 
1.226     brouard   779: 
                    780:   
1.133     brouard   781:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    782:            Institut national d'études démographiques, Paris.
1.126     brouard   783:   This software have been partly granted by Euro-REVES, a concerted action
                    784:   from the European Union.
                    785:   It is copyrighted identically to a GNU software product, ie programme and
                    786:   software can be distributed freely for non commercial use. Latest version
                    787:   can be accessed at http://euroreves.ined.fr/imach .
                    788: 
                    789:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    790:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    791:   
                    792:   **********************************************************************/
                    793: /*
                    794:   main
                    795:   read parameterfile
                    796:   read datafile
                    797:   concatwav
                    798:   freqsummary
                    799:   if (mle >= 1)
                    800:     mlikeli
                    801:   print results files
                    802:   if mle==1 
                    803:      computes hessian
                    804:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    805:       begin-prev-date,...
                    806:   open gnuplot file
                    807:   open html file
1.145     brouard   808:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    809:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    810:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    811:     freexexit2 possible for memory heap.
                    812: 
                    813:   h Pij x                         | pij_nom  ficrestpij
                    814:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    815:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    816:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    817: 
                    818:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    819:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    820:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    821:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    822:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    823: 
1.126     brouard   824:   forecasting if prevfcast==1 prevforecast call prevalence()
                    825:   health expectancies
                    826:   Variance-covariance of DFLE
                    827:   prevalence()
                    828:    movingaverage()
                    829:   varevsij() 
                    830:   if popbased==1 varevsij(,popbased)
                    831:   total life expectancies
                    832:   Variance of period (stable) prevalence
                    833:  end
                    834: */
                    835: 
1.187     brouard   836: /* #define DEBUG */
                    837: /* #define DEBUGBRENT */
1.203     brouard   838: /* #define DEBUGLINMIN */
                    839: /* #define DEBUGHESS */
                    840: #define DEBUGHESSIJ
1.224     brouard   841: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   842: #define POWELL /* Instead of NLOPT */
1.224     brouard   843: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   844: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    845: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   846: 
                    847: #include <math.h>
                    848: #include <stdio.h>
                    849: #include <stdlib.h>
                    850: #include <string.h>
1.226     brouard   851: #include <ctype.h>
1.159     brouard   852: 
                    853: #ifdef _WIN32
                    854: #include <io.h>
1.172     brouard   855: #include <windows.h>
                    856: #include <tchar.h>
1.159     brouard   857: #else
1.126     brouard   858: #include <unistd.h>
1.159     brouard   859: #endif
1.126     brouard   860: 
                    861: #include <limits.h>
                    862: #include <sys/types.h>
1.171     brouard   863: 
                    864: #if defined(__GNUC__)
                    865: #include <sys/utsname.h> /* Doesn't work on Windows */
                    866: #endif
                    867: 
1.126     brouard   868: #include <sys/stat.h>
                    869: #include <errno.h>
1.159     brouard   870: /* extern int errno; */
1.126     brouard   871: 
1.157     brouard   872: /* #ifdef LINUX */
                    873: /* #include <time.h> */
                    874: /* #include "timeval.h" */
                    875: /* #else */
                    876: /* #include <sys/time.h> */
                    877: /* #endif */
                    878: 
1.126     brouard   879: #include <time.h>
                    880: 
1.136     brouard   881: #ifdef GSL
                    882: #include <gsl/gsl_errno.h>
                    883: #include <gsl/gsl_multimin.h>
                    884: #endif
                    885: 
1.167     brouard   886: 
1.162     brouard   887: #ifdef NLOPT
                    888: #include <nlopt.h>
                    889: typedef struct {
                    890:   double (* function)(double [] );
                    891: } myfunc_data ;
                    892: #endif
                    893: 
1.126     brouard   894: /* #include <libintl.h> */
                    895: /* #define _(String) gettext (String) */
                    896: 
1.141     brouard   897: #define MAXLINE 1024 /* Was 256. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   898: 
                    899: #define GNUPLOTPROGRAM "gnuplot"
                    900: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    901: #define FILENAMELENGTH 132
                    902: 
                    903: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    904: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    905: 
1.144     brouard   906: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    907: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   908: 
                    909: #define NINTERVMAX 8
1.144     brouard   910: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    911: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    912: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   913: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   914: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    915: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   916: #define MAXN 20000
1.144     brouard   917: #define YEARM 12. /**< Number of months per year */
1.218     brouard   918: /* #define AGESUP 130 */
                    919: #define AGESUP 150
                    920: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard   921: #define AGEBASE 40
1.194     brouard   922: #define AGEOVERFLOW 1.e20
1.164     brouard   923: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard   924: #ifdef _WIN32
                    925: #define DIRSEPARATOR '\\'
                    926: #define CHARSEPARATOR "\\"
                    927: #define ODIRSEPARATOR '/'
                    928: #else
1.126     brouard   929: #define DIRSEPARATOR '/'
                    930: #define CHARSEPARATOR "/"
                    931: #define ODIRSEPARATOR '\\'
                    932: #endif
                    933: 
1.244   ! brouard   934: /* $Id: imach.c,v 1.243 2016/09/02 06:45:35 brouard Exp $ */
1.126     brouard   935: /* $State: Exp $ */
1.196     brouard   936: #include "version.h"
                    937: char version[]=__IMACH_VERSION__;
1.224     brouard   938: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.244   ! brouard   939: char fullversion[]="$Revision: 1.243 $ $Date: 2016/09/02 06:45:35 $"; 
1.126     brouard   940: char strstart[80];
                    941: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard   942: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard   943: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard   944: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                    945: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                    946: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard   947: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                    948: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard   949: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                    950: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                    951: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard   952: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                    953: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard   954: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard   955: int nsd=0; /**< Total number of single dummy variables (output) */
                    956: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard   957: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard   958: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard   959: int ntveff=0; /**< ntveff number of effective time varying variables */
                    960: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard   961: int cptcov=0; /* Working variable */
1.218     brouard   962: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard   963: int npar=NPARMAX;
                    964: int nlstate=2; /* Number of live states */
                    965: int ndeath=1; /* Number of dead states */
1.130     brouard   966: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard   967: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard   968: int popbased=0;
                    969: 
                    970: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard   971: int maxwav=0; /* Maxim number of waves */
                    972: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                    973: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                    974: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard   975:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard   976: int mle=1, weightopt=0;
1.126     brouard   977: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                    978: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                    979: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                    980:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard   981: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard   982: int selected(int kvar); /* Is covariate kvar selected for printing results */
                    983: 
1.130     brouard   984: double jmean=1; /* Mean space between 2 waves */
1.145     brouard   985: double **matprod2(); /* test */
1.126     brouard   986: double **oldm, **newm, **savm; /* Working pointers to matrices */
                    987: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard   988: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                    989: 
1.136     brouard   990: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard   991: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard   992: FILE *ficlog, *ficrespow;
1.130     brouard   993: int globpr=0; /* Global variable for printing or not */
1.126     brouard   994: double fretone; /* Only one call to likelihood */
1.130     brouard   995: long ipmx=0; /* Number of contributions */
1.126     brouard   996: double sw; /* Sum of weights */
                    997: char filerespow[FILENAMELENGTH];
                    998: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                    999: FILE *ficresilk;
                   1000: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1001: FILE *ficresprobmorprev;
                   1002: FILE *fichtm, *fichtmcov; /* Html File */
                   1003: FILE *ficreseij;
                   1004: char filerese[FILENAMELENGTH];
                   1005: FILE *ficresstdeij;
                   1006: char fileresstde[FILENAMELENGTH];
                   1007: FILE *ficrescveij;
                   1008: char filerescve[FILENAMELENGTH];
                   1009: FILE  *ficresvij;
                   1010: char fileresv[FILENAMELENGTH];
                   1011: FILE  *ficresvpl;
                   1012: char fileresvpl[FILENAMELENGTH];
                   1013: char title[MAXLINE];
1.234     brouard  1014: char model[MAXLINE]; /**< The model line */
1.217     brouard  1015: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1016: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1017: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1018: char command[FILENAMELENGTH];
                   1019: int  outcmd=0;
                   1020: 
1.217     brouard  1021: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1022: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1023: char filelog[FILENAMELENGTH]; /* Log file */
                   1024: char filerest[FILENAMELENGTH];
                   1025: char fileregp[FILENAMELENGTH];
                   1026: char popfile[FILENAMELENGTH];
                   1027: 
                   1028: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1029: 
1.157     brouard  1030: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1031: /* struct timezone tzp; */
                   1032: /* extern int gettimeofday(); */
                   1033: struct tm tml, *gmtime(), *localtime();
                   1034: 
                   1035: extern time_t time();
                   1036: 
                   1037: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1038: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1039: struct tm tm;
                   1040: 
1.126     brouard  1041: char strcurr[80], strfor[80];
                   1042: 
                   1043: char *endptr;
                   1044: long lval;
                   1045: double dval;
                   1046: 
                   1047: #define NR_END 1
                   1048: #define FREE_ARG char*
                   1049: #define FTOL 1.0e-10
                   1050: 
                   1051: #define NRANSI 
1.240     brouard  1052: #define ITMAX 200
                   1053: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1054: 
                   1055: #define TOL 2.0e-4 
                   1056: 
                   1057: #define CGOLD 0.3819660 
                   1058: #define ZEPS 1.0e-10 
                   1059: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1060: 
                   1061: #define GOLD 1.618034 
                   1062: #define GLIMIT 100.0 
                   1063: #define TINY 1.0e-20 
                   1064: 
                   1065: static double maxarg1,maxarg2;
                   1066: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1067: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1068:   
                   1069: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1070: #define rint(a) floor(a+0.5)
1.166     brouard  1071: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1072: #define mytinydouble 1.0e-16
1.166     brouard  1073: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1074: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1075: /* static double dsqrarg; */
                   1076: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1077: static double sqrarg;
                   1078: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1079: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1080: int agegomp= AGEGOMP;
                   1081: 
                   1082: int imx; 
                   1083: int stepm=1;
                   1084: /* Stepm, step in month: minimum step interpolation*/
                   1085: 
                   1086: int estepm;
                   1087: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1088: 
                   1089: int m,nb;
                   1090: long *num;
1.197     brouard  1091: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1092: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1093:                   covariate for which somebody answered excluding 
                   1094:                   undefined. Usually 2: 0 and 1. */
                   1095: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1096:                             covariate for which somebody answered including 
                   1097:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1098: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1099: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1100: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1101: double *ageexmed,*agecens;
                   1102: double dateintmean=0;
                   1103: 
                   1104: double *weight;
                   1105: int **s; /* Status */
1.141     brouard  1106: double *agedc;
1.145     brouard  1107: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1108:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1109:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.225     brouard  1110: double **coqvar; /* Fixed quantitative covariate iqv */
                   1111: double ***cotvar; /* Time varying covariate itv */
                   1112: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1113: double  idx; 
                   1114: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1115: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1116: /*k          1  2   3   4     5    6    7     8    9 */
                   1117: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1118: /* Tndvar[k]    1   2   3               4          5 */
                   1119: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1120: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1121: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1122: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1123: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1124: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1125: /* Tprod[i]=k           4               7            */
                   1126: /* Tage[i]=k                  5               8      */
                   1127: /* */
                   1128: /* Type                    */
                   1129: /* V         1  2  3  4  5 */
                   1130: /*           F  F  V  V  V */
                   1131: /*           D  Q  D  D  Q */
                   1132: /*                         */
                   1133: int *TvarsD;
                   1134: int *TvarsDind;
                   1135: int *TvarsQ;
                   1136: int *TvarsQind;
                   1137: 
1.235     brouard  1138: #define MAXRESULTLINES 10
                   1139: int nresult=0;
                   1140: int TKresult[MAXRESULTLINES];
1.237     brouard  1141: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1142: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1143: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1144: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1145: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1146: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1147: 
1.234     brouard  1148: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1149: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1150: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1151: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1152: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1153: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1154: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1155: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1156: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1157: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1158: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1159: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1160: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1161: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1162: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1163: 
1.230     brouard  1164: int *Tvarsel; /**< Selected covariates for output */
                   1165: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1166: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1167: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1168: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1169: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1170: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1171: int *Tage;
1.227     brouard  1172: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1173: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1174: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1175: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1176: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1177: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1178: int **Tvard;
                   1179: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1180: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1181: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1182:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1183:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1184: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1185: double *lsurv, *lpop, *tpop;
                   1186: 
1.231     brouard  1187: #define FD 1; /* Fixed dummy covariate */
                   1188: #define FQ 2; /* Fixed quantitative covariate */
                   1189: #define FP 3; /* Fixed product covariate */
                   1190: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1191: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1192: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1193: #define VD 10; /* Varying dummy covariate */
                   1194: #define VQ 11; /* Varying quantitative covariate */
                   1195: #define VP 12; /* Varying product covariate */
                   1196: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1197: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1198: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1199: #define APFD 16; /* Age product * fixed dummy covariate */
                   1200: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1201: #define APVD 18; /* Age product * varying dummy covariate */
                   1202: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1203: 
                   1204: #define FTYPE 1; /* Fixed covariate */
                   1205: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1206: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1207: 
                   1208: struct kmodel{
                   1209:        int maintype; /* main type */
                   1210:        int subtype; /* subtype */
                   1211: };
                   1212: struct kmodel modell[NCOVMAX];
                   1213: 
1.143     brouard  1214: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1215: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1216: 
                   1217: /**************** split *************************/
                   1218: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1219: {
                   1220:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1221:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1222:   */ 
                   1223:   char *ss;                            /* pointer */
1.186     brouard  1224:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1225: 
                   1226:   l1 = strlen(path );                  /* length of path */
                   1227:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1228:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1229:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1230:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1231:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1232:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1233:     /* get current working directory */
                   1234:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1235: #ifdef WIN32
                   1236:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1237: #else
                   1238:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1239: #endif
1.126     brouard  1240:       return( GLOCK_ERROR_GETCWD );
                   1241:     }
                   1242:     /* got dirc from getcwd*/
                   1243:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1244:   } else {                             /* strip directory from path */
1.126     brouard  1245:     ss++;                              /* after this, the filename */
                   1246:     l2 = strlen( ss );                 /* length of filename */
                   1247:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1248:     strcpy( name, ss );                /* save file name */
                   1249:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1250:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1251:     printf(" DIRC2 = %s \n",dirc);
                   1252:   }
                   1253:   /* We add a separator at the end of dirc if not exists */
                   1254:   l1 = strlen( dirc );                 /* length of directory */
                   1255:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1256:     dirc[l1] =  DIRSEPARATOR;
                   1257:     dirc[l1+1] = 0; 
                   1258:     printf(" DIRC3 = %s \n",dirc);
                   1259:   }
                   1260:   ss = strrchr( name, '.' );           /* find last / */
                   1261:   if (ss >0){
                   1262:     ss++;
                   1263:     strcpy(ext,ss);                    /* save extension */
                   1264:     l1= strlen( name);
                   1265:     l2= strlen(ss)+1;
                   1266:     strncpy( finame, name, l1-l2);
                   1267:     finame[l1-l2]= 0;
                   1268:   }
                   1269: 
                   1270:   return( 0 );                         /* we're done */
                   1271: }
                   1272: 
                   1273: 
                   1274: /******************************************/
                   1275: 
                   1276: void replace_back_to_slash(char *s, char*t)
                   1277: {
                   1278:   int i;
                   1279:   int lg=0;
                   1280:   i=0;
                   1281:   lg=strlen(t);
                   1282:   for(i=0; i<= lg; i++) {
                   1283:     (s[i] = t[i]);
                   1284:     if (t[i]== '\\') s[i]='/';
                   1285:   }
                   1286: }
                   1287: 
1.132     brouard  1288: char *trimbb(char *out, char *in)
1.137     brouard  1289: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1290:   char *s;
                   1291:   s=out;
                   1292:   while (*in != '\0'){
1.137     brouard  1293:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1294:       in++;
                   1295:     }
                   1296:     *out++ = *in++;
                   1297:   }
                   1298:   *out='\0';
                   1299:   return s;
                   1300: }
                   1301: 
1.187     brouard  1302: /* char *substrchaine(char *out, char *in, char *chain) */
                   1303: /* { */
                   1304: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1305: /*   char *s, *t; */
                   1306: /*   t=in;s=out; */
                   1307: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1308: /*     *out++ = *in++; */
                   1309: /*   } */
                   1310: 
                   1311: /*   /\* *in matches *chain *\/ */
                   1312: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1313: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1314: /*   } */
                   1315: /*   in--; chain--; */
                   1316: /*   while ( (*in != '\0')){ */
                   1317: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1318: /*     *out++ = *in++; */
                   1319: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1320: /*   } */
                   1321: /*   *out='\0'; */
                   1322: /*   out=s; */
                   1323: /*   return out; */
                   1324: /* } */
                   1325: char *substrchaine(char *out, char *in, char *chain)
                   1326: {
                   1327:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1328:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1329: 
                   1330:   char *strloc;
                   1331: 
                   1332:   strcpy (out, in); 
                   1333:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1334:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1335:   if(strloc != NULL){ 
                   1336:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1337:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1338:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1339:   }
                   1340:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1341:   return out;
                   1342: }
                   1343: 
                   1344: 
1.145     brouard  1345: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1346: {
1.187     brouard  1347:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1348:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1349:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1350:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1351:   */
1.160     brouard  1352:   char *s, *t;
1.145     brouard  1353:   t=in;s=in;
                   1354:   while ((*in != occ) && (*in != '\0')){
                   1355:     *alocc++ = *in++;
                   1356:   }
                   1357:   if( *in == occ){
                   1358:     *(alocc)='\0';
                   1359:     s=++in;
                   1360:   }
                   1361:  
                   1362:   if (s == t) {/* occ not found */
                   1363:     *(alocc-(in-s))='\0';
                   1364:     in=s;
                   1365:   }
                   1366:   while ( *in != '\0'){
                   1367:     *blocc++ = *in++;
                   1368:   }
                   1369: 
                   1370:   *blocc='\0';
                   1371:   return t;
                   1372: }
1.137     brouard  1373: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1374: {
1.187     brouard  1375:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1376:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1377:      gives blocc="abcdef2ghi" and alocc="j".
                   1378:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1379:   */
                   1380:   char *s, *t;
                   1381:   t=in;s=in;
                   1382:   while (*in != '\0'){
                   1383:     while( *in == occ){
                   1384:       *blocc++ = *in++;
                   1385:       s=in;
                   1386:     }
                   1387:     *blocc++ = *in++;
                   1388:   }
                   1389:   if (s == t) /* occ not found */
                   1390:     *(blocc-(in-s))='\0';
                   1391:   else
                   1392:     *(blocc-(in-s)-1)='\0';
                   1393:   in=s;
                   1394:   while ( *in != '\0'){
                   1395:     *alocc++ = *in++;
                   1396:   }
                   1397: 
                   1398:   *alocc='\0';
                   1399:   return s;
                   1400: }
                   1401: 
1.126     brouard  1402: int nbocc(char *s, char occ)
                   1403: {
                   1404:   int i,j=0;
                   1405:   int lg=20;
                   1406:   i=0;
                   1407:   lg=strlen(s);
                   1408:   for(i=0; i<= lg; i++) {
1.234     brouard  1409:     if  (s[i] == occ ) j++;
1.126     brouard  1410:   }
                   1411:   return j;
                   1412: }
                   1413: 
1.137     brouard  1414: /* void cutv(char *u,char *v, char*t, char occ) */
                   1415: /* { */
                   1416: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1417: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1418: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1419: /*   int i,lg,j,p=0; */
                   1420: /*   i=0; */
                   1421: /*   lg=strlen(t); */
                   1422: /*   for(j=0; j<=lg-1; j++) { */
                   1423: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1424: /*   } */
1.126     brouard  1425: 
1.137     brouard  1426: /*   for(j=0; j<p; j++) { */
                   1427: /*     (u[j] = t[j]); */
                   1428: /*   } */
                   1429: /*      u[p]='\0'; */
1.126     brouard  1430: 
1.137     brouard  1431: /*    for(j=0; j<= lg; j++) { */
                   1432: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1433: /*   } */
                   1434: /* } */
1.126     brouard  1435: 
1.160     brouard  1436: #ifdef _WIN32
                   1437: char * strsep(char **pp, const char *delim)
                   1438: {
                   1439:   char *p, *q;
                   1440:          
                   1441:   if ((p = *pp) == NULL)
                   1442:     return 0;
                   1443:   if ((q = strpbrk (p, delim)) != NULL)
                   1444:   {
                   1445:     *pp = q + 1;
                   1446:     *q = '\0';
                   1447:   }
                   1448:   else
                   1449:     *pp = 0;
                   1450:   return p;
                   1451: }
                   1452: #endif
                   1453: 
1.126     brouard  1454: /********************** nrerror ********************/
                   1455: 
                   1456: void nrerror(char error_text[])
                   1457: {
                   1458:   fprintf(stderr,"ERREUR ...\n");
                   1459:   fprintf(stderr,"%s\n",error_text);
                   1460:   exit(EXIT_FAILURE);
                   1461: }
                   1462: /*********************** vector *******************/
                   1463: double *vector(int nl, int nh)
                   1464: {
                   1465:   double *v;
                   1466:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1467:   if (!v) nrerror("allocation failure in vector");
                   1468:   return v-nl+NR_END;
                   1469: }
                   1470: 
                   1471: /************************ free vector ******************/
                   1472: void free_vector(double*v, int nl, int nh)
                   1473: {
                   1474:   free((FREE_ARG)(v+nl-NR_END));
                   1475: }
                   1476: 
                   1477: /************************ivector *******************************/
                   1478: int *ivector(long nl,long nh)
                   1479: {
                   1480:   int *v;
                   1481:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1482:   if (!v) nrerror("allocation failure in ivector");
                   1483:   return v-nl+NR_END;
                   1484: }
                   1485: 
                   1486: /******************free ivector **************************/
                   1487: void free_ivector(int *v, long nl, long nh)
                   1488: {
                   1489:   free((FREE_ARG)(v+nl-NR_END));
                   1490: }
                   1491: 
                   1492: /************************lvector *******************************/
                   1493: long *lvector(long nl,long nh)
                   1494: {
                   1495:   long *v;
                   1496:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1497:   if (!v) nrerror("allocation failure in ivector");
                   1498:   return v-nl+NR_END;
                   1499: }
                   1500: 
                   1501: /******************free lvector **************************/
                   1502: void free_lvector(long *v, long nl, long nh)
                   1503: {
                   1504:   free((FREE_ARG)(v+nl-NR_END));
                   1505: }
                   1506: 
                   1507: /******************* imatrix *******************************/
                   1508: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1509:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1510: { 
                   1511:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1512:   int **m; 
                   1513:   
                   1514:   /* allocate pointers to rows */ 
                   1515:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1516:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1517:   m += NR_END; 
                   1518:   m -= nrl; 
                   1519:   
                   1520:   
                   1521:   /* allocate rows and set pointers to them */ 
                   1522:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1523:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1524:   m[nrl] += NR_END; 
                   1525:   m[nrl] -= ncl; 
                   1526:   
                   1527:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1528:   
                   1529:   /* return pointer to array of pointers to rows */ 
                   1530:   return m; 
                   1531: } 
                   1532: 
                   1533: /****************** free_imatrix *************************/
                   1534: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1535:       int **m;
                   1536:       long nch,ncl,nrh,nrl; 
                   1537:      /* free an int matrix allocated by imatrix() */ 
                   1538: { 
                   1539:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1540:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1541: } 
                   1542: 
                   1543: /******************* matrix *******************************/
                   1544: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1545: {
                   1546:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1547:   double **m;
                   1548: 
                   1549:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1550:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1551:   m += NR_END;
                   1552:   m -= nrl;
                   1553: 
                   1554:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1555:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1556:   m[nrl] += NR_END;
                   1557:   m[nrl] -= ncl;
                   1558: 
                   1559:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1560:   return m;
1.145     brouard  1561:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1562: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1563: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1564:    */
                   1565: }
                   1566: 
                   1567: /*************************free matrix ************************/
                   1568: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1569: {
                   1570:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1571:   free((FREE_ARG)(m+nrl-NR_END));
                   1572: }
                   1573: 
                   1574: /******************* ma3x *******************************/
                   1575: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1576: {
                   1577:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1578:   double ***m;
                   1579: 
                   1580:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1581:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1582:   m += NR_END;
                   1583:   m -= nrl;
                   1584: 
                   1585:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1586:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1587:   m[nrl] += NR_END;
                   1588:   m[nrl] -= ncl;
                   1589: 
                   1590:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1591: 
                   1592:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1593:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1594:   m[nrl][ncl] += NR_END;
                   1595:   m[nrl][ncl] -= nll;
                   1596:   for (j=ncl+1; j<=nch; j++) 
                   1597:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1598:   
                   1599:   for (i=nrl+1; i<=nrh; i++) {
                   1600:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1601:     for (j=ncl+1; j<=nch; j++) 
                   1602:       m[i][j]=m[i][j-1]+nlay;
                   1603:   }
                   1604:   return m; 
                   1605:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1606:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1607:   */
                   1608: }
                   1609: 
                   1610: /*************************free ma3x ************************/
                   1611: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1612: {
                   1613:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1614:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1615:   free((FREE_ARG)(m+nrl-NR_END));
                   1616: }
                   1617: 
                   1618: /*************** function subdirf ***********/
                   1619: char *subdirf(char fileres[])
                   1620: {
                   1621:   /* Caution optionfilefiname is hidden */
                   1622:   strcpy(tmpout,optionfilefiname);
                   1623:   strcat(tmpout,"/"); /* Add to the right */
                   1624:   strcat(tmpout,fileres);
                   1625:   return tmpout;
                   1626: }
                   1627: 
                   1628: /*************** function subdirf2 ***********/
                   1629: char *subdirf2(char fileres[], char *preop)
                   1630: {
                   1631:   
                   1632:   /* Caution optionfilefiname is hidden */
                   1633:   strcpy(tmpout,optionfilefiname);
                   1634:   strcat(tmpout,"/");
                   1635:   strcat(tmpout,preop);
                   1636:   strcat(tmpout,fileres);
                   1637:   return tmpout;
                   1638: }
                   1639: 
                   1640: /*************** function subdirf3 ***********/
                   1641: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1642: {
                   1643:   
                   1644:   /* Caution optionfilefiname is hidden */
                   1645:   strcpy(tmpout,optionfilefiname);
                   1646:   strcat(tmpout,"/");
                   1647:   strcat(tmpout,preop);
                   1648:   strcat(tmpout,preop2);
                   1649:   strcat(tmpout,fileres);
                   1650:   return tmpout;
                   1651: }
1.213     brouard  1652:  
                   1653: /*************** function subdirfext ***********/
                   1654: char *subdirfext(char fileres[], char *preop, char *postop)
                   1655: {
                   1656:   
                   1657:   strcpy(tmpout,preop);
                   1658:   strcat(tmpout,fileres);
                   1659:   strcat(tmpout,postop);
                   1660:   return tmpout;
                   1661: }
1.126     brouard  1662: 
1.213     brouard  1663: /*************** function subdirfext3 ***********/
                   1664: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1665: {
                   1666:   
                   1667:   /* Caution optionfilefiname is hidden */
                   1668:   strcpy(tmpout,optionfilefiname);
                   1669:   strcat(tmpout,"/");
                   1670:   strcat(tmpout,preop);
                   1671:   strcat(tmpout,fileres);
                   1672:   strcat(tmpout,postop);
                   1673:   return tmpout;
                   1674: }
                   1675:  
1.162     brouard  1676: char *asc_diff_time(long time_sec, char ascdiff[])
                   1677: {
                   1678:   long sec_left, days, hours, minutes;
                   1679:   days = (time_sec) / (60*60*24);
                   1680:   sec_left = (time_sec) % (60*60*24);
                   1681:   hours = (sec_left) / (60*60) ;
                   1682:   sec_left = (sec_left) %(60*60);
                   1683:   minutes = (sec_left) /60;
                   1684:   sec_left = (sec_left) % (60);
                   1685:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1686:   return ascdiff;
                   1687: }
                   1688: 
1.126     brouard  1689: /***************** f1dim *************************/
                   1690: extern int ncom; 
                   1691: extern double *pcom,*xicom;
                   1692: extern double (*nrfunc)(double []); 
                   1693:  
                   1694: double f1dim(double x) 
                   1695: { 
                   1696:   int j; 
                   1697:   double f;
                   1698:   double *xt; 
                   1699:  
                   1700:   xt=vector(1,ncom); 
                   1701:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1702:   f=(*nrfunc)(xt); 
                   1703:   free_vector(xt,1,ncom); 
                   1704:   return f; 
                   1705: } 
                   1706: 
                   1707: /*****************brent *************************/
                   1708: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1709: {
                   1710:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1711:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1712:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1713:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1714:    * returned function value. 
                   1715:   */
1.126     brouard  1716:   int iter; 
                   1717:   double a,b,d,etemp;
1.159     brouard  1718:   double fu=0,fv,fw,fx;
1.164     brouard  1719:   double ftemp=0.;
1.126     brouard  1720:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1721:   double e=0.0; 
                   1722:  
                   1723:   a=(ax < cx ? ax : cx); 
                   1724:   b=(ax > cx ? ax : cx); 
                   1725:   x=w=v=bx; 
                   1726:   fw=fv=fx=(*f)(x); 
                   1727:   for (iter=1;iter<=ITMAX;iter++) { 
                   1728:     xm=0.5*(a+b); 
                   1729:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1730:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1731:     printf(".");fflush(stdout);
                   1732:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1733: #ifdef DEBUGBRENT
1.126     brouard  1734:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1735:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1736:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1737: #endif
                   1738:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1739:       *xmin=x; 
                   1740:       return fx; 
                   1741:     } 
                   1742:     ftemp=fu;
                   1743:     if (fabs(e) > tol1) { 
                   1744:       r=(x-w)*(fx-fv); 
                   1745:       q=(x-v)*(fx-fw); 
                   1746:       p=(x-v)*q-(x-w)*r; 
                   1747:       q=2.0*(q-r); 
                   1748:       if (q > 0.0) p = -p; 
                   1749:       q=fabs(q); 
                   1750:       etemp=e; 
                   1751:       e=d; 
                   1752:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1753:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1754:       else { 
1.224     brouard  1755:                                d=p/q; 
                   1756:                                u=x+d; 
                   1757:                                if (u-a < tol2 || b-u < tol2) 
                   1758:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1759:       } 
                   1760:     } else { 
                   1761:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1762:     } 
                   1763:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1764:     fu=(*f)(u); 
                   1765:     if (fu <= fx) { 
                   1766:       if (u >= x) a=x; else b=x; 
                   1767:       SHFT(v,w,x,u) 
1.183     brouard  1768:       SHFT(fv,fw,fx,fu) 
                   1769:     } else { 
                   1770:       if (u < x) a=u; else b=u; 
                   1771:       if (fu <= fw || w == x) { 
1.224     brouard  1772:                                v=w; 
                   1773:                                w=u; 
                   1774:                                fv=fw; 
                   1775:                                fw=fu; 
1.183     brouard  1776:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1777:                                v=u; 
                   1778:                                fv=fu; 
1.183     brouard  1779:       } 
                   1780:     } 
1.126     brouard  1781:   } 
                   1782:   nrerror("Too many iterations in brent"); 
                   1783:   *xmin=x; 
                   1784:   return fx; 
                   1785: } 
                   1786: 
                   1787: /****************** mnbrak ***********************/
                   1788: 
                   1789: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1790:            double (*func)(double)) 
1.183     brouard  1791: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1792: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1793: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1794: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1795:    */
1.126     brouard  1796:   double ulim,u,r,q, dum;
                   1797:   double fu; 
1.187     brouard  1798: 
                   1799:   double scale=10.;
                   1800:   int iterscale=0;
                   1801: 
                   1802:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1803:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1804: 
                   1805: 
                   1806:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1807:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1808:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1809:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1810:   /* } */
                   1811: 
1.126     brouard  1812:   if (*fb > *fa) { 
                   1813:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1814:     SHFT(dum,*fb,*fa,dum) 
                   1815:   } 
1.126     brouard  1816:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1817:   *fc=(*func)(*cx); 
1.183     brouard  1818: #ifdef DEBUG
1.224     brouard  1819:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1820:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1821: #endif
1.224     brouard  1822:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1823:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1824:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1825:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1826:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1827:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1828:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1829:       fu=(*func)(u); 
1.163     brouard  1830: #ifdef DEBUG
                   1831:       /* f(x)=A(x-u)**2+f(u) */
                   1832:       double A, fparabu; 
                   1833:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1834:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1835:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1836:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1837:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1838:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1839:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1840:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1841: #endif 
1.184     brouard  1842: #ifdef MNBRAKORIGINAL
1.183     brouard  1843: #else
1.191     brouard  1844: /*       if (fu > *fc) { */
                   1845: /* #ifdef DEBUG */
                   1846: /*       printf("mnbrak4  fu > fc \n"); */
                   1847: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1848: /* #endif */
                   1849: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1850: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1851: /*     dum=u; /\* Shifting c and u *\/ */
                   1852: /*     u = *cx; */
                   1853: /*     *cx = dum; */
                   1854: /*     dum = fu; */
                   1855: /*     fu = *fc; */
                   1856: /*     *fc =dum; */
                   1857: /*       } else { /\* end *\/ */
                   1858: /* #ifdef DEBUG */
                   1859: /*       printf("mnbrak3  fu < fc \n"); */
                   1860: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1861: /* #endif */
                   1862: /*     dum=u; /\* Shifting c and u *\/ */
                   1863: /*     u = *cx; */
                   1864: /*     *cx = dum; */
                   1865: /*     dum = fu; */
                   1866: /*     fu = *fc; */
                   1867: /*     *fc =dum; */
                   1868: /*       } */
1.224     brouard  1869: #ifdef DEBUGMNBRAK
                   1870:                 double A, fparabu; 
                   1871:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1872:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1873:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1874:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1875: #endif
1.191     brouard  1876:       dum=u; /* Shifting c and u */
                   1877:       u = *cx;
                   1878:       *cx = dum;
                   1879:       dum = fu;
                   1880:       fu = *fc;
                   1881:       *fc =dum;
1.183     brouard  1882: #endif
1.162     brouard  1883:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1884: #ifdef DEBUG
1.224     brouard  1885:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1886:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1887: #endif
1.126     brouard  1888:       fu=(*func)(u); 
                   1889:       if (fu < *fc) { 
1.183     brouard  1890: #ifdef DEBUG
1.224     brouard  1891:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1892:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1893: #endif
                   1894:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1895:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1896: #ifdef DEBUG
                   1897:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1898: #endif
                   1899:       } 
1.162     brouard  1900:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1901: #ifdef DEBUG
1.224     brouard  1902:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1903:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1904: #endif
1.126     brouard  1905:       u=ulim; 
                   1906:       fu=(*func)(u); 
1.183     brouard  1907:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1908: #ifdef DEBUG
1.224     brouard  1909:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1910:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1911: #endif
1.126     brouard  1912:       u=(*cx)+GOLD*(*cx-*bx); 
                   1913:       fu=(*func)(u); 
1.224     brouard  1914: #ifdef DEBUG
                   1915:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1916:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1917: #endif
1.183     brouard  1918:     } /* end tests */
1.126     brouard  1919:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  1920:     SHFT(*fa,*fb,*fc,fu) 
                   1921: #ifdef DEBUG
1.224     brouard  1922:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   1923:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  1924: #endif
                   1925:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  1926: } 
                   1927: 
                   1928: /*************** linmin ************************/
1.162     brouard  1929: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   1930: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   1931: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   1932: the value of func at the returned location p . This is actually all accomplished by calling the
                   1933: routines mnbrak and brent .*/
1.126     brouard  1934: int ncom; 
                   1935: double *pcom,*xicom;
                   1936: double (*nrfunc)(double []); 
                   1937:  
1.224     brouard  1938: #ifdef LINMINORIGINAL
1.126     brouard  1939: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  1940: #else
                   1941: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   1942: #endif
1.126     brouard  1943: { 
                   1944:   double brent(double ax, double bx, double cx, 
                   1945:               double (*f)(double), double tol, double *xmin); 
                   1946:   double f1dim(double x); 
                   1947:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   1948:              double *fc, double (*func)(double)); 
                   1949:   int j; 
                   1950:   double xx,xmin,bx,ax; 
                   1951:   double fx,fb,fa;
1.187     brouard  1952: 
1.203     brouard  1953: #ifdef LINMINORIGINAL
                   1954: #else
                   1955:   double scale=10., axs, xxs; /* Scale added for infinity */
                   1956: #endif
                   1957:   
1.126     brouard  1958:   ncom=n; 
                   1959:   pcom=vector(1,n); 
                   1960:   xicom=vector(1,n); 
                   1961:   nrfunc=func; 
                   1962:   for (j=1;j<=n;j++) { 
                   1963:     pcom[j]=p[j]; 
1.202     brouard  1964:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  1965:   } 
1.187     brouard  1966: 
1.203     brouard  1967: #ifdef LINMINORIGINAL
                   1968:   xx=1.;
                   1969: #else
                   1970:   axs=0.0;
                   1971:   xxs=1.;
                   1972:   do{
                   1973:     xx= xxs;
                   1974: #endif
1.187     brouard  1975:     ax=0.;
                   1976:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   1977:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   1978:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   1979:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   1980:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   1981:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   1982:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  1983: #ifdef LINMINORIGINAL
                   1984: #else
                   1985:     if (fx != fx){
1.224     brouard  1986:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   1987:                        printf("|");
                   1988:                        fprintf(ficlog,"|");
1.203     brouard  1989: #ifdef DEBUGLINMIN
1.224     brouard  1990:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  1991: #endif
                   1992:     }
1.224     brouard  1993:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  1994: #endif
                   1995:   
1.191     brouard  1996: #ifdef DEBUGLINMIN
                   1997:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  1998:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  1999: #endif
1.224     brouard  2000: #ifdef LINMINORIGINAL
                   2001: #else
                   2002:        if(fb == fx){ /* Flat function in the direction */
                   2003:                xmin=xx;
                   2004:     *flat=1;
                   2005:        }else{
                   2006:     *flat=0;
                   2007: #endif
                   2008:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2009:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2010:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2011:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2012:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2013:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2014: #ifdef DEBUG
1.224     brouard  2015:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2016:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2017: #endif
                   2018: #ifdef LINMINORIGINAL
                   2019: #else
                   2020:                        }
1.126     brouard  2021: #endif
1.191     brouard  2022: #ifdef DEBUGLINMIN
                   2023:   printf("linmin end ");
1.202     brouard  2024:   fprintf(ficlog,"linmin end ");
1.191     brouard  2025: #endif
1.126     brouard  2026:   for (j=1;j<=n;j++) { 
1.203     brouard  2027: #ifdef LINMINORIGINAL
                   2028:     xi[j] *= xmin; 
                   2029: #else
                   2030: #ifdef DEBUGLINMIN
                   2031:     if(xxs <1.0)
                   2032:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2033: #endif
                   2034:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2035: #ifdef DEBUGLINMIN
                   2036:     if(xxs <1.0)
                   2037:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2038: #endif
                   2039: #endif
1.187     brouard  2040:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2041:   } 
1.191     brouard  2042: #ifdef DEBUGLINMIN
1.203     brouard  2043:   printf("\n");
1.191     brouard  2044:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2045:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2046:   for (j=1;j<=n;j++) { 
1.202     brouard  2047:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2048:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2049:     if(j % ncovmodel == 0){
1.191     brouard  2050:       printf("\n");
1.202     brouard  2051:       fprintf(ficlog,"\n");
                   2052:     }
1.191     brouard  2053:   }
1.203     brouard  2054: #else
1.191     brouard  2055: #endif
1.126     brouard  2056:   free_vector(xicom,1,n); 
                   2057:   free_vector(pcom,1,n); 
                   2058: } 
                   2059: 
                   2060: 
                   2061: /*************** powell ************************/
1.162     brouard  2062: /*
                   2063: Minimization of a function func of n variables. Input consists of an initial starting point
                   2064: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2065: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2066: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2067: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2068: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2069:  */
1.224     brouard  2070: #ifdef LINMINORIGINAL
                   2071: #else
                   2072:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2073:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2074: #endif
1.126     brouard  2075: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2076:            double (*func)(double [])) 
                   2077: { 
1.224     brouard  2078: #ifdef LINMINORIGINAL
                   2079:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2080:              double (*func)(double [])); 
1.224     brouard  2081: #else 
1.241     brouard  2082:  void linmin(double p[], double xi[], int n, double *fret,
                   2083:             double (*func)(double []),int *flat); 
1.224     brouard  2084: #endif
1.239     brouard  2085:  int i,ibig,j,jk,k; 
1.126     brouard  2086:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2087:   double directest;
1.126     brouard  2088:   double fp,fptt;
                   2089:   double *xits;
                   2090:   int niterf, itmp;
1.224     brouard  2091: #ifdef LINMINORIGINAL
                   2092: #else
                   2093: 
                   2094:   flatdir=ivector(1,n); 
                   2095:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2096: #endif
1.126     brouard  2097: 
                   2098:   pt=vector(1,n); 
                   2099:   ptt=vector(1,n); 
                   2100:   xit=vector(1,n); 
                   2101:   xits=vector(1,n); 
                   2102:   *fret=(*func)(p); 
                   2103:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2104:   rcurr_time = time(NULL);  
1.126     brouard  2105:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2106:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2107:     ibig=0; 
                   2108:     del=0.0; 
1.157     brouard  2109:     rlast_time=rcurr_time;
                   2110:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2111:     rcurr_time = time(NULL);  
                   2112:     curr_time = *localtime(&rcurr_time);
                   2113:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2114:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2115: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2116:     for (i=1;i<=n;i++) {
1.126     brouard  2117:       fprintf(ficrespow," %.12lf", p[i]);
                   2118:     }
1.239     brouard  2119:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2120:     printf("\n#model=  1      +     age ");
                   2121:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2122:     if(nagesqr==1){
1.241     brouard  2123:        printf("  + age*age  ");
                   2124:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2125:     }
                   2126:     for(j=1;j <=ncovmodel-2;j++){
                   2127:       if(Typevar[j]==0) {
                   2128:        printf("  +      V%d  ",Tvar[j]);
                   2129:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2130:       }else if(Typevar[j]==1) {
                   2131:        printf("  +    V%d*age ",Tvar[j]);
                   2132:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2133:       }else if(Typevar[j]==2) {
                   2134:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2135:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2136:       }
                   2137:     }
1.126     brouard  2138:     printf("\n");
1.239     brouard  2139: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2140: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2141:     fprintf(ficlog,"\n");
1.239     brouard  2142:     for(i=1,jk=1; i <=nlstate; i++){
                   2143:       for(k=1; k <=(nlstate+ndeath); k++){
                   2144:        if (k != i) {
                   2145:          printf("%d%d ",i,k);
                   2146:          fprintf(ficlog,"%d%d ",i,k);
                   2147:          for(j=1; j <=ncovmodel; j++){
                   2148:            printf("%12.7f ",p[jk]);
                   2149:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2150:            jk++; 
                   2151:          }
                   2152:          printf("\n");
                   2153:          fprintf(ficlog,"\n");
                   2154:        }
                   2155:       }
                   2156:     }
1.241     brouard  2157:     if(*iter <=3 && *iter >1){
1.157     brouard  2158:       tml = *localtime(&rcurr_time);
                   2159:       strcpy(strcurr,asctime(&tml));
                   2160:       rforecast_time=rcurr_time; 
1.126     brouard  2161:       itmp = strlen(strcurr);
                   2162:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2163:        strcurr[itmp-1]='\0';
1.162     brouard  2164:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2165:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2166:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2167:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2168:        forecast_time = *localtime(&rforecast_time);
                   2169:        strcpy(strfor,asctime(&forecast_time));
                   2170:        itmp = strlen(strfor);
                   2171:        if(strfor[itmp-1]=='\n')
                   2172:          strfor[itmp-1]='\0';
                   2173:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2174:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2175:       }
                   2176:     }
1.187     brouard  2177:     for (i=1;i<=n;i++) { /* For each direction i */
                   2178:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2179:       fptt=(*fret); 
                   2180: #ifdef DEBUG
1.203     brouard  2181:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2182:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2183: #endif
1.203     brouard  2184:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2185:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2186: #ifdef LINMINORIGINAL
1.188     brouard  2187:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2188: #else
                   2189:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2190:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2191: #endif
                   2192:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2193:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2194:                                /* because that direction will be replaced unless the gain del is small */
                   2195:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2196:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2197:                                /* with the new direction. */
                   2198:                                del=fabs(fptt-(*fret)); 
                   2199:                                ibig=i; 
1.126     brouard  2200:       } 
                   2201: #ifdef DEBUG
                   2202:       printf("%d %.12e",i,(*fret));
                   2203:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2204:       for (j=1;j<=n;j++) {
1.224     brouard  2205:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2206:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2207:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2208:       }
                   2209:       for(j=1;j<=n;j++) {
1.225     brouard  2210:                                printf(" p(%d)=%.12e",j,p[j]);
                   2211:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2212:       }
                   2213:       printf("\n");
                   2214:       fprintf(ficlog,"\n");
                   2215: #endif
1.187     brouard  2216:     } /* end loop on each direction i */
                   2217:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2218:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2219:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2220:       for(j=1;j<=n;j++) {
1.225     brouard  2221:                                if(flatdir[j] >0){
                   2222:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2223:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2224:                                }
                   2225:                                /* printf("\n"); */
                   2226:                                /* fprintf(ficlog,"\n"); */
                   2227:                        }
1.243     brouard  2228:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2229:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2230:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2231:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2232:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2233:       /* decreased of more than 3.84  */
                   2234:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2235:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2236:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2237:                        
1.188     brouard  2238:       /* Starting the program with initial values given by a former maximization will simply change */
                   2239:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2240:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2241:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2242: #ifdef DEBUG
                   2243:       int k[2],l;
                   2244:       k[0]=1;
                   2245:       k[1]=-1;
                   2246:       printf("Max: %.12e",(*func)(p));
                   2247:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2248:       for (j=1;j<=n;j++) {
                   2249:        printf(" %.12e",p[j]);
                   2250:        fprintf(ficlog," %.12e",p[j]);
                   2251:       }
                   2252:       printf("\n");
                   2253:       fprintf(ficlog,"\n");
                   2254:       for(l=0;l<=1;l++) {
                   2255:        for (j=1;j<=n;j++) {
                   2256:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2257:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2258:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2259:        }
                   2260:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2261:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2262:       }
                   2263: #endif
                   2264: 
1.224     brouard  2265: #ifdef LINMINORIGINAL
                   2266: #else
                   2267:       free_ivector(flatdir,1,n); 
                   2268: #endif
1.126     brouard  2269:       free_vector(xit,1,n); 
                   2270:       free_vector(xits,1,n); 
                   2271:       free_vector(ptt,1,n); 
                   2272:       free_vector(pt,1,n); 
                   2273:       return; 
1.192     brouard  2274:     } /* enough precision */ 
1.240     brouard  2275:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2276:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2277:       ptt[j]=2.0*p[j]-pt[j]; 
                   2278:       xit[j]=p[j]-pt[j]; 
                   2279:       pt[j]=p[j]; 
                   2280:     } 
1.181     brouard  2281:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2282: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2283:                if (*iter <=4) {
1.225     brouard  2284: #else
                   2285: #endif
1.224     brouard  2286: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2287: #else
1.161     brouard  2288:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2289: #endif
1.162     brouard  2290:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2291:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2292:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2293:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2294:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2295:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2296:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2297:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2298:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2299:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2300:       /* mu² and del² are equal when f3=f1 */
                   2301:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2302:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2303:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2304:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2305: #ifdef NRCORIGINAL
                   2306:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2307: #else
                   2308:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2309:       t= t- del*SQR(fp-fptt);
1.183     brouard  2310: #endif
1.202     brouard  2311:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2312: #ifdef DEBUG
1.181     brouard  2313:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2314:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2315:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2316:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2317:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2318:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2319:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2320:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2321: #endif
1.183     brouard  2322: #ifdef POWELLORIGINAL
                   2323:       if (t < 0.0) { /* Then we use it for new direction */
                   2324: #else
1.182     brouard  2325:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2326:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2327:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2328:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2329:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2330:       } 
1.181     brouard  2331:       if (directest < 0.0) { /* Then we use it for new direction */
                   2332: #endif
1.191     brouard  2333: #ifdef DEBUGLINMIN
1.234     brouard  2334:        printf("Before linmin in direction P%d-P0\n",n);
                   2335:        for (j=1;j<=n;j++) {
                   2336:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2337:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2338:          if(j % ncovmodel == 0){
                   2339:            printf("\n");
                   2340:            fprintf(ficlog,"\n");
                   2341:          }
                   2342:        }
1.224     brouard  2343: #endif
                   2344: #ifdef LINMINORIGINAL
1.234     brouard  2345:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2346: #else
1.234     brouard  2347:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2348:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2349: #endif
1.234     brouard  2350:        
1.191     brouard  2351: #ifdef DEBUGLINMIN
1.234     brouard  2352:        for (j=1;j<=n;j++) { 
                   2353:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2354:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2355:          if(j % ncovmodel == 0){
                   2356:            printf("\n");
                   2357:            fprintf(ficlog,"\n");
                   2358:          }
                   2359:        }
1.224     brouard  2360: #endif
1.234     brouard  2361:        for (j=1;j<=n;j++) { 
                   2362:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2363:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2364:        }
1.224     brouard  2365: #ifdef LINMINORIGINAL
                   2366: #else
1.234     brouard  2367:        for (j=1, flatd=0;j<=n;j++) {
                   2368:          if(flatdir[j]>0)
                   2369:            flatd++;
                   2370:        }
                   2371:        if(flatd >0){
                   2372:          printf("%d flat directions\n",flatd);
                   2373:          fprintf(ficlog,"%d flat directions\n",flatd);
                   2374:          for (j=1;j<=n;j++) { 
                   2375:            if(flatdir[j]>0){
                   2376:              printf("%d ",j);
                   2377:              fprintf(ficlog,"%d ",j);
                   2378:            }
                   2379:          }
                   2380:          printf("\n");
                   2381:          fprintf(ficlog,"\n");
                   2382:        }
1.191     brouard  2383: #endif
1.234     brouard  2384:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2385:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2386:        
1.126     brouard  2387: #ifdef DEBUG
1.234     brouard  2388:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2389:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2390:        for(j=1;j<=n;j++){
                   2391:          printf(" %lf",xit[j]);
                   2392:          fprintf(ficlog," %lf",xit[j]);
                   2393:        }
                   2394:        printf("\n");
                   2395:        fprintf(ficlog,"\n");
1.126     brouard  2396: #endif
1.192     brouard  2397:       } /* end of t or directest negative */
1.224     brouard  2398: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2399: #else
1.234     brouard  2400:       } /* end if (fptt < fp)  */
1.192     brouard  2401: #endif
1.225     brouard  2402: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2403:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2404: #else
1.224     brouard  2405: #endif
1.234     brouard  2406:                } /* loop iteration */ 
1.126     brouard  2407: } 
1.234     brouard  2408:   
1.126     brouard  2409: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2410:   
1.235     brouard  2411:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2412:   {
1.235     brouard  2413:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2414:        (and selected quantitative values in nres)
                   2415:        by left multiplying the unit
1.234     brouard  2416:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2417:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2418:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2419:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2420:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2421:   /* Initial matrix pimij */
                   2422:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2423:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2424:   /*  0,                   0                  , 1} */
                   2425:   /*
                   2426:    * and after some iteration: */
                   2427:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2428:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2429:   /*  0,                   0                  , 1} */
                   2430:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2431:   /* {0.51571254859325999, 0.4842874514067399, */
                   2432:   /*  0.51326036147820708, 0.48673963852179264} */
                   2433:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2434:     
1.126     brouard  2435:   int i, ii,j,k;
1.209     brouard  2436:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2437:   /* double **matprod2(); */ /* test */
1.218     brouard  2438:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2439:   double **newm;
1.209     brouard  2440:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2441:   int ncvloop=0;
1.169     brouard  2442:   
1.209     brouard  2443:   min=vector(1,nlstate);
                   2444:   max=vector(1,nlstate);
                   2445:   meandiff=vector(1,nlstate);
                   2446: 
1.218     brouard  2447:        /* Starting with matrix unity */
1.126     brouard  2448:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2449:     for (j=1;j<=nlstate+ndeath;j++){
                   2450:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2451:     }
1.169     brouard  2452:   
                   2453:   cov[1]=1.;
                   2454:   
                   2455:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2456:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2457:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2458:     ncvloop++;
1.126     brouard  2459:     newm=savm;
                   2460:     /* Covariates have to be included here again */
1.138     brouard  2461:     cov[2]=agefin;
1.187     brouard  2462:     if(nagesqr==1)
                   2463:       cov[3]= agefin*agefin;;
1.234     brouard  2464:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2465:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2466:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2467:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2468:     }
                   2469:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2470:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2471:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2472:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2473:     }
1.237     brouard  2474:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2475:       if(Dummy[Tvar[Tage[k]]]){
                   2476:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2477:       } else{
1.235     brouard  2478:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2479:       }
1.235     brouard  2480:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2481:     }
1.237     brouard  2482:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2483:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2484:       if(Dummy[Tvard[k][1]==0]){
                   2485:        if(Dummy[Tvard[k][2]==0]){
                   2486:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2487:        }else{
                   2488:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2489:        }
                   2490:       }else{
                   2491:        if(Dummy[Tvard[k][2]==0]){
                   2492:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2493:        }else{
                   2494:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2495:        }
                   2496:       }
1.234     brouard  2497:     }
1.138     brouard  2498:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2499:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2500:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2501:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2502:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2503:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2504:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2505:     
1.126     brouard  2506:     savm=oldm;
                   2507:     oldm=newm;
1.209     brouard  2508: 
                   2509:     for(j=1; j<=nlstate; j++){
                   2510:       max[j]=0.;
                   2511:       min[j]=1.;
                   2512:     }
                   2513:     for(i=1;i<=nlstate;i++){
                   2514:       sumnew=0;
                   2515:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2516:       for(j=1; j<=nlstate; j++){ 
                   2517:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2518:        max[j]=FMAX(max[j],prlim[i][j]);
                   2519:        min[j]=FMIN(min[j],prlim[i][j]);
                   2520:       }
                   2521:     }
                   2522: 
1.126     brouard  2523:     maxmax=0.;
1.209     brouard  2524:     for(j=1; j<=nlstate; j++){
                   2525:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2526:       maxmax=FMAX(maxmax,meandiff[j]);
                   2527:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2528:     } /* j loop */
1.203     brouard  2529:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2530:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2531:     if(maxmax < ftolpl){
1.209     brouard  2532:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2533:       free_vector(min,1,nlstate);
                   2534:       free_vector(max,1,nlstate);
                   2535:       free_vector(meandiff,1,nlstate);
1.126     brouard  2536:       return prlim;
                   2537:     }
1.169     brouard  2538:   } /* age loop */
1.208     brouard  2539:     /* After some age loop it doesn't converge */
1.209     brouard  2540:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2541: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2542:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2543:   free_vector(min,1,nlstate);
                   2544:   free_vector(max,1,nlstate);
                   2545:   free_vector(meandiff,1,nlstate);
1.208     brouard  2546:   
1.169     brouard  2547:   return prlim; /* should not reach here */
1.126     brouard  2548: }
                   2549: 
1.217     brouard  2550: 
                   2551:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2552: 
1.218     brouard  2553:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2554:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2555:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2556: {
1.218     brouard  2557:   /* Computes the prevalence limit in each live state at age x and covariate ij by left multiplying the unit
1.217     brouard  2558:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2559:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2560:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2561:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2562:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2563:   /* Initial matrix pimij */
                   2564:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2565:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2566:   /*  0,                   0                  , 1} */
                   2567:   /*
                   2568:    * and after some iteration: */
                   2569:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2570:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2571:   /*  0,                   0                  , 1} */
                   2572:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2573:   /* {0.51571254859325999, 0.4842874514067399, */
                   2574:   /*  0.51326036147820708, 0.48673963852179264} */
                   2575:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2576: 
                   2577:   int i, ii,j,k;
                   2578:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2579:   /* double **matprod2(); */ /* test */
                   2580:   double **out, cov[NCOVMAX+1], **bmij();
                   2581:   double **newm;
1.218     brouard  2582:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2583:   double        **oldm, **savm;  /* for use */
                   2584: 
1.217     brouard  2585:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2586:   int ncvloop=0;
                   2587:   
                   2588:   min=vector(1,nlstate);
                   2589:   max=vector(1,nlstate);
                   2590:   meandiff=vector(1,nlstate);
                   2591: 
1.218     brouard  2592:        dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2593:        oldm=oldms; savm=savms;
                   2594: 
                   2595:        /* Starting with matrix unity */
                   2596:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   2597:                for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2598:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2599:     }
                   2600:   
                   2601:   cov[1]=1.;
                   2602:   
                   2603:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2604:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2605:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2606:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2607:     ncvloop++;
1.218     brouard  2608:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2609:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2610:     /* Covariates have to be included here again */
                   2611:     cov[2]=agefin;
                   2612:     if(nagesqr==1)
                   2613:       cov[3]= agefin*agefin;;
1.242     brouard  2614:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2615:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2616:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   2617:       /* printf("bprevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   2618:     }
                   2619:     /* for (k=1; k<=cptcovn;k++) { */
                   2620:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2621:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2622:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2623:     /* } */
                   2624:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2625:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2626:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2627:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2628:     }
                   2629:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2630:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2631:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2632:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2633:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2634:       if(Dummy[Tvar[Tage[k]]]){
                   2635:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2636:       } else{
                   2637:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2638:       }
                   2639:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2640:     }
                   2641:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2642:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2643:       if(Dummy[Tvard[k][1]==0]){
                   2644:        if(Dummy[Tvard[k][2]==0]){
                   2645:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2646:        }else{
                   2647:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2648:        }
                   2649:       }else{
                   2650:        if(Dummy[Tvard[k][2]==0]){
                   2651:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2652:        }else{
                   2653:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2654:        }
                   2655:       }
1.217     brouard  2656:     }
                   2657:     
                   2658:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2659:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2660:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2661:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2662:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2663:                /* ij should be linked to the correct index of cov */
                   2664:                /* age and covariate values ij are in 'cov', but we need to pass
                   2665:                 * ij for the observed prevalence at age and status and covariate
                   2666:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2667:                 */
                   2668:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2669:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2670:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.217     brouard  2671:     savm=oldm;
                   2672:     oldm=newm;
                   2673:     for(j=1; j<=nlstate; j++){
                   2674:       max[j]=0.;
                   2675:       min[j]=1.;
                   2676:     }
                   2677:     for(j=1; j<=nlstate; j++){ 
                   2678:       for(i=1;i<=nlstate;i++){
1.234     brouard  2679:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2680:        bprlim[i][j]= newm[i][j];
                   2681:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2682:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2683:       }
                   2684:     }
1.218     brouard  2685:                
1.217     brouard  2686:     maxmax=0.;
                   2687:     for(i=1; i<=nlstate; i++){
                   2688:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2689:       maxmax=FMAX(maxmax,meandiff[i]);
                   2690:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
                   2691:     } /* j loop */
                   2692:     *ncvyear= -( (int)age- (int)agefin);
1.218     brouard  2693:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear);*/
1.217     brouard  2694:     if(maxmax < ftolpl){
1.220     brouard  2695:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2696:       free_vector(min,1,nlstate);
                   2697:       free_vector(max,1,nlstate);
                   2698:       free_vector(meandiff,1,nlstate);
                   2699:       return bprlim;
                   2700:     }
                   2701:   } /* age loop */
                   2702:     /* After some age loop it doesn't converge */
                   2703:   printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
                   2704: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2705:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2706:   free_vector(min,1,nlstate);
                   2707:   free_vector(max,1,nlstate);
                   2708:   free_vector(meandiff,1,nlstate);
                   2709:   
                   2710:   return bprlim; /* should not reach here */
                   2711: }
                   2712: 
1.126     brouard  2713: /*************** transition probabilities ***************/ 
                   2714: 
                   2715: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2716: {
1.138     brouard  2717:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2718:      computes the probability to be observed in state j being in state i by appying the
                   2719:      model to the ncovmodel covariates (including constant and age).
                   2720:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2721:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2722:      ncth covariate in the global vector x is given by the formula:
                   2723:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2724:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2725:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2726:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2727:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2728:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2729:   */
                   2730:   double s1, lnpijopii;
1.126     brouard  2731:   /*double t34;*/
1.164     brouard  2732:   int i,j, nc, ii, jj;
1.126     brouard  2733: 
1.223     brouard  2734:   for(i=1; i<= nlstate; i++){
                   2735:     for(j=1; j<i;j++){
                   2736:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2737:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2738:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2739:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2740:       }
                   2741:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2742:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2743:     }
                   2744:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2745:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2746:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2747:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2748:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2749:       }
                   2750:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2751:     }
                   2752:   }
1.218     brouard  2753:   
1.223     brouard  2754:   for(i=1; i<= nlstate; i++){
                   2755:     s1=0;
                   2756:     for(j=1; j<i; j++){
                   2757:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2758:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2759:     }
                   2760:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2761:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2762:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2763:     }
                   2764:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2765:     ps[i][i]=1./(s1+1.);
                   2766:     /* Computing other pijs */
                   2767:     for(j=1; j<i; j++)
                   2768:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2769:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2770:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2771:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2772:   } /* end i */
1.218     brouard  2773:   
1.223     brouard  2774:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2775:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2776:       ps[ii][jj]=0;
                   2777:       ps[ii][ii]=1;
                   2778:     }
                   2779:   }
1.218     brouard  2780:   
                   2781:   
1.223     brouard  2782:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2783:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2784:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2785:   /*   } */
                   2786:   /*   printf("\n "); */
                   2787:   /* } */
                   2788:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2789:   /*
                   2790:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2791:                goto end;*/
1.223     brouard  2792:   return ps;
1.126     brouard  2793: }
                   2794: 
1.218     brouard  2795: /*************** backward transition probabilities ***************/ 
                   2796: 
                   2797:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2798: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2799:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2800: {
1.222     brouard  2801:   /* Computes the backward probability at age agefin and covariate ij
                   2802:    * and returns in **ps as well as **bmij.
                   2803:    */
1.218     brouard  2804:   int i, ii, j,k;
1.222     brouard  2805:   
                   2806:   double **out, **pmij();
                   2807:   double sumnew=0.;
1.218     brouard  2808:   double agefin;
1.222     brouard  2809:   
                   2810:   double **dnewm, **dsavm, **doldm;
                   2811:   double **bbmij;
                   2812:   
1.218     brouard  2813:   doldm=ddoldms; /* global pointers */
1.222     brouard  2814:   dnewm=ddnewms;
                   2815:   dsavm=ddsavms;
                   2816:   
                   2817:   agefin=cov[2];
                   2818:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
                   2819:      the observed prevalence (with this covariate ij) */
                   2820:   dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate);
                   2821:   /* We do have the matrix Px in savm  and we need pij */
                   2822:   for (j=1;j<=nlstate+ndeath;j++){
                   2823:     sumnew=0.; /* w1 p11 + w2 p21 only on live states */
                   2824:     for (ii=1;ii<=nlstate;ii++){
                   2825:       sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij];
                   2826:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
                   2827:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2828:       if(sumnew >= 1.e-10){
                   2829:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
                   2830:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2831:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
                   2832:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2833:        /* }else */
                   2834:        doldm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2835:       }else{
1.242     brouard  2836:        ;
                   2837:        /* printf("ii=%d, i=%d, doldm=%lf dsavm=%lf, probs=%lf, sumnew=%lf,agefin=%d\n",ii,j,doldm[ii][j],dsavm[ii][j],prevacurrent[(int)agefin][ii][ij],sumnew, (int)agefin); */
1.222     brouard  2838:       }
                   2839:     } /*End ii */
                   2840:   } /* End j, At the end doldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2841:   /* left Product of this diag matrix by dsavm=Px (newm=dsavm*doldm) */
                   2842:   bbmij=matprod2(dnewm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, doldm); /* Bug Valgrind */
                   2843:   /* dsavm=doldm; /\* dsavm is now diag [1/(w_1p1i+w_2 p2i)] but can be overwritten*\/ */
                   2844:   /* doldm=dnewm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2845:   /* dnewm=dsavm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2846:   /* left Product of this matrix by diag matrix of prevalences (savm) */
                   2847:   for (j=1;j<=nlstate+ndeath;j++){
                   2848:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2849:       dsavm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij] : 0.0);
                   2850:     }
                   2851:   } /* End j, At the end oldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2852:   ps=matprod2(doldm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dnewm); /* Bug Valgrind */
                   2853:   /* newm or out is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
                   2854:   /* end bmij */
                   2855:   return ps; 
1.218     brouard  2856: }
1.217     brouard  2857: /*************** transition probabilities ***************/ 
                   2858: 
1.218     brouard  2859: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2860: {
                   2861:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2862:      computes the probability to be observed in state j being in state i by appying the
                   2863:      model to the ncovmodel covariates (including constant and age).
                   2864:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2865:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2866:      ncth covariate in the global vector x is given by the formula:
                   2867:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2868:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2869:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2870:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2871:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2872:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2873:   */
                   2874:   double s1, lnpijopii;
                   2875:   /*double t34;*/
                   2876:   int i,j, nc, ii, jj;
                   2877: 
1.234     brouard  2878:   for(i=1; i<= nlstate; i++){
                   2879:     for(j=1; j<i;j++){
                   2880:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2881:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2882:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2883:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2884:       }
                   2885:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2886:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2887:     }
                   2888:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2889:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2890:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2891:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2892:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2893:       }
                   2894:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2895:     }
                   2896:   }
                   2897:   
                   2898:   for(i=1; i<= nlstate; i++){
                   2899:     s1=0;
                   2900:     for(j=1; j<i; j++){
                   2901:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2902:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2903:     }
                   2904:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2905:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2906:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2907:     }
                   2908:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2909:     ps[i][i]=1./(s1+1.);
                   2910:     /* Computing other pijs */
                   2911:     for(j=1; j<i; j++)
                   2912:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2913:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2914:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2915:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2916:   } /* end i */
                   2917:   
                   2918:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2919:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2920:       ps[ii][jj]=0;
                   2921:       ps[ii][ii]=1;
                   2922:     }
                   2923:   }
                   2924:   /* Added for backcast */ /* Transposed matrix too */
                   2925:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2926:     s1=0.;
                   2927:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   2928:       s1+=ps[ii][jj];
                   2929:     }
                   2930:     for(ii=1; ii<= nlstate; ii++){
                   2931:       ps[ii][jj]=ps[ii][jj]/s1;
                   2932:     }
                   2933:   }
                   2934:   /* Transposition */
                   2935:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2936:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   2937:       s1=ps[ii][jj];
                   2938:       ps[ii][jj]=ps[jj][ii];
                   2939:       ps[jj][ii]=s1;
                   2940:     }
                   2941:   }
                   2942:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2943:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2944:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2945:   /*   } */
                   2946:   /*   printf("\n "); */
                   2947:   /* } */
                   2948:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2949:   /*
                   2950:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   2951:     goto end;*/
                   2952:   return ps;
1.217     brouard  2953: }
                   2954: 
                   2955: 
1.126     brouard  2956: /**************** Product of 2 matrices ******************/
                   2957: 
1.145     brouard  2958: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  2959: {
                   2960:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   2961:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   2962:   /* in, b, out are matrice of pointers which should have been initialized 
                   2963:      before: only the contents of out is modified. The function returns
                   2964:      a pointer to pointers identical to out */
1.145     brouard  2965:   int i, j, k;
1.126     brouard  2966:   for(i=nrl; i<= nrh; i++)
1.145     brouard  2967:     for(k=ncolol; k<=ncoloh; k++){
                   2968:       out[i][k]=0.;
                   2969:       for(j=ncl; j<=nch; j++)
                   2970:        out[i][k] +=in[i][j]*b[j][k];
                   2971:     }
1.126     brouard  2972:   return out;
                   2973: }
                   2974: 
                   2975: 
                   2976: /************* Higher Matrix Product ***************/
                   2977: 
1.235     brouard  2978: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  2979: {
1.218     brouard  2980:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  2981:      'nhstepm*hstepm*stepm' months (i.e. until
                   2982:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   2983:      nhstepm*hstepm matrices. 
                   2984:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   2985:      (typically every 2 years instead of every month which is too big 
                   2986:      for the memory).
                   2987:      Model is determined by parameters x and covariates have to be 
                   2988:      included manually here. 
                   2989: 
                   2990:      */
                   2991: 
                   2992:   int i, j, d, h, k;
1.131     brouard  2993:   double **out, cov[NCOVMAX+1];
1.126     brouard  2994:   double **newm;
1.187     brouard  2995:   double agexact;
1.214     brouard  2996:   double agebegin, ageend;
1.126     brouard  2997: 
                   2998:   /* Hstepm could be zero and should return the unit matrix */
                   2999:   for (i=1;i<=nlstate+ndeath;i++)
                   3000:     for (j=1;j<=nlstate+ndeath;j++){
                   3001:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3002:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3003:     }
                   3004:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3005:   for(h=1; h <=nhstepm; h++){
                   3006:     for(d=1; d <=hstepm; d++){
                   3007:       newm=savm;
                   3008:       /* Covariates have to be included here again */
                   3009:       cov[1]=1.;
1.214     brouard  3010:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3011:       cov[2]=agexact;
                   3012:       if(nagesqr==1)
1.227     brouard  3013:        cov[3]= agexact*agexact;
1.235     brouard  3014:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3015:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3016:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3017:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3018:       }
                   3019:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3020:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3021:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3022:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3023:       }
                   3024:       for (k=1; k<=cptcovage;k++){
                   3025:        if(Dummy[Tvar[Tage[k]]]){
                   3026:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3027:        } else{
                   3028:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3029:        }
                   3030:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3031:       }
                   3032:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3033:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3034:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3035:       }
                   3036:       /* for (k=1; k<=cptcovn;k++)  */
                   3037:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3038:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3039:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3040:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3041:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3042:       
                   3043:       
1.126     brouard  3044:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3045:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3046:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3047:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3048:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3049:       /* if((int)age == 70){ */
                   3050:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3051:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3052:       /*         printf("%d pmmij ",i); */
                   3053:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3054:       /*           printf("%f ",pmmij[i][j]); */
                   3055:       /*         } */
                   3056:       /*         printf(" oldm "); */
                   3057:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3058:       /*           printf("%f ",oldm[i][j]); */
                   3059:       /*         } */
                   3060:       /*         printf("\n"); */
                   3061:       /*       } */
                   3062:       /* } */
1.126     brouard  3063:       savm=oldm;
                   3064:       oldm=newm;
                   3065:     }
                   3066:     for(i=1; i<=nlstate+ndeath; i++)
                   3067:       for(j=1;j<=nlstate+ndeath;j++) {
1.218     brouard  3068:                                po[i][j][h]=newm[i][j];
                   3069:                                /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3070:       }
1.128     brouard  3071:     /*printf("h=%d ",h);*/
1.126     brouard  3072:   } /* end h */
1.218     brouard  3073:        /*     printf("\n H=%d \n",h); */
1.126     brouard  3074:   return po;
                   3075: }
                   3076: 
1.217     brouard  3077: /************* Higher Back Matrix Product ***************/
1.218     brouard  3078: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.222     brouard  3079: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij )
1.217     brouard  3080: {
1.218     brouard  3081:   /* Computes the transition matrix starting at age 'age' over
1.217     brouard  3082:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3083:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3084:      nhstepm*hstepm matrices.
                   3085:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3086:      (typically every 2 years instead of every month which is too big
1.217     brouard  3087:      for the memory).
1.218     brouard  3088:      Model is determined by parameters x and covariates have to be
                   3089:      included manually here.
1.217     brouard  3090: 
1.222     brouard  3091:   */
1.217     brouard  3092: 
                   3093:   int i, j, d, h, k;
                   3094:   double **out, cov[NCOVMAX+1];
                   3095:   double **newm;
                   3096:   double agexact;
                   3097:   double agebegin, ageend;
1.222     brouard  3098:   double **oldm, **savm;
1.217     brouard  3099: 
1.222     brouard  3100:   oldm=oldms;savm=savms;
1.217     brouard  3101:   /* Hstepm could be zero and should return the unit matrix */
                   3102:   for (i=1;i<=nlstate+ndeath;i++)
                   3103:     for (j=1;j<=nlstate+ndeath;j++){
                   3104:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3105:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3106:     }
                   3107:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3108:   for(h=1; h <=nhstepm; h++){
                   3109:     for(d=1; d <=hstepm; d++){
                   3110:       newm=savm;
                   3111:       /* Covariates have to be included here again */
                   3112:       cov[1]=1.;
                   3113:       agexact=age-((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
                   3114:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3115:       cov[2]=agexact;
                   3116:       if(nagesqr==1)
1.222     brouard  3117:        cov[3]= agexact*agexact;
1.218     brouard  3118:       for (k=1; k<=cptcovn;k++)
1.222     brouard  3119:        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   3120:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.217     brouard  3121:       for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
1.222     brouard  3122:        /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   3123:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3124:       /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
1.217     brouard  3125:       for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
1.222     brouard  3126:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3127:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
1.218     brouard  3128:                        
                   3129:                        
1.217     brouard  3130:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3131:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3132:       /* Careful transposed matrix */
1.222     brouard  3133:       /* age is in cov[2] */
1.218     brouard  3134:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3135:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3136:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3137:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3138:       /* if((int)age == 70){ */
                   3139:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3140:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3141:       /*         printf("%d pmmij ",i); */
                   3142:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3143:       /*           printf("%f ",pmmij[i][j]); */
                   3144:       /*         } */
                   3145:       /*         printf(" oldm "); */
                   3146:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3147:       /*           printf("%f ",oldm[i][j]); */
                   3148:       /*         } */
                   3149:       /*         printf("\n"); */
                   3150:       /*       } */
                   3151:       /* } */
                   3152:       savm=oldm;
                   3153:       oldm=newm;
                   3154:     }
                   3155:     for(i=1; i<=nlstate+ndeath; i++)
                   3156:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3157:        po[i][j][h]=newm[i][j];
                   3158:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.217     brouard  3159:       }
                   3160:     /*printf("h=%d ",h);*/
                   3161:   } /* end h */
1.222     brouard  3162:   /*     printf("\n H=%d \n",h); */
1.217     brouard  3163:   return po;
                   3164: }
                   3165: 
                   3166: 
1.162     brouard  3167: #ifdef NLOPT
                   3168:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3169:   double fret;
                   3170:   double *xt;
                   3171:   int j;
                   3172:   myfunc_data *d2 = (myfunc_data *) pd;
                   3173: /* xt = (p1-1); */
                   3174:   xt=vector(1,n); 
                   3175:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3176: 
                   3177:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3178:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3179:   printf("Function = %.12lf ",fret);
                   3180:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3181:   printf("\n");
                   3182:  free_vector(xt,1,n);
                   3183:   return fret;
                   3184: }
                   3185: #endif
1.126     brouard  3186: 
                   3187: /*************** log-likelihood *************/
                   3188: double func( double *x)
                   3189: {
1.226     brouard  3190:   int i, ii, j, k, mi, d, kk;
                   3191:   int ioffset=0;
                   3192:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3193:   double **out;
                   3194:   double lli; /* Individual log likelihood */
                   3195:   int s1, s2;
1.228     brouard  3196:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3197:   double bbh, survp;
                   3198:   long ipmx;
                   3199:   double agexact;
                   3200:   /*extern weight */
                   3201:   /* We are differentiating ll according to initial status */
                   3202:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3203:   /*for(i=1;i<imx;i++) 
                   3204:     printf(" %d\n",s[4][i]);
                   3205:   */
1.162     brouard  3206: 
1.226     brouard  3207:   ++countcallfunc;
1.162     brouard  3208: 
1.226     brouard  3209:   cov[1]=1.;
1.126     brouard  3210: 
1.226     brouard  3211:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3212:   ioffset=0;
1.226     brouard  3213:   if(mle==1){
                   3214:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3215:       /* Computes the values of the ncovmodel covariates of the model
                   3216:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3217:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3218:         to be observed in j being in i according to the model.
                   3219:       */
1.243     brouard  3220:       ioffset=2+nagesqr ;
1.233     brouard  3221:    /* Fixed */
1.234     brouard  3222:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3223:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3224:       }
1.226     brouard  3225:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3226:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3227:         has been calculated etc */
                   3228:       /* For an individual i, wav[i] gives the number of effective waves */
                   3229:       /* We compute the contribution to Likelihood of each effective transition
                   3230:         mw[mi][i] is real wave of the mi th effectve wave */
                   3231:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3232:         s2=s[mw[mi+1][i]][i];
                   3233:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3234:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3235:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3236:       */
                   3237:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3238:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3239:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3240:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3241:        }
                   3242:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3243:          for (j=1;j<=nlstate+ndeath;j++){
                   3244:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3245:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3246:          }
                   3247:        for(d=0; d<dh[mi][i]; d++){
                   3248:          newm=savm;
                   3249:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3250:          cov[2]=agexact;
                   3251:          if(nagesqr==1)
                   3252:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3253:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3254:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3255:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3256:          else
                   3257:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3258:          }
                   3259:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3260:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3261:          savm=oldm;
                   3262:          oldm=newm;
                   3263:        } /* end mult */
                   3264:        
                   3265:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3266:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3267:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3268:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3269:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3270:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3271:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3272:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3273:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3274:                                 * -stepm/2 to stepm/2 .
                   3275:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3276:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3277:                                 */
1.234     brouard  3278:        s1=s[mw[mi][i]][i];
                   3279:        s2=s[mw[mi+1][i]][i];
                   3280:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3281:        /* bias bh is positive if real duration
                   3282:         * is higher than the multiple of stepm and negative otherwise.
                   3283:         */
                   3284:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3285:        if( s2 > nlstate){ 
                   3286:          /* i.e. if s2 is a death state and if the date of death is known 
                   3287:             then the contribution to the likelihood is the probability to 
                   3288:             die between last step unit time and current  step unit time, 
                   3289:             which is also equal to probability to die before dh 
                   3290:             minus probability to die before dh-stepm . 
                   3291:             In version up to 0.92 likelihood was computed
                   3292:             as if date of death was unknown. Death was treated as any other
                   3293:             health state: the date of the interview describes the actual state
                   3294:             and not the date of a change in health state. The former idea was
                   3295:             to consider that at each interview the state was recorded
                   3296:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3297:             introduced the exact date of death then we should have modified
                   3298:             the contribution of an exact death to the likelihood. This new
                   3299:             contribution is smaller and very dependent of the step unit
                   3300:             stepm. It is no more the probability to die between last interview
                   3301:             and month of death but the probability to survive from last
                   3302:             interview up to one month before death multiplied by the
                   3303:             probability to die within a month. Thanks to Chris
                   3304:             Jackson for correcting this bug.  Former versions increased
                   3305:             mortality artificially. The bad side is that we add another loop
                   3306:             which slows down the processing. The difference can be up to 10%
                   3307:             lower mortality.
                   3308:          */
                   3309:          /* If, at the beginning of the maximization mostly, the
                   3310:             cumulative probability or probability to be dead is
                   3311:             constant (ie = 1) over time d, the difference is equal to
                   3312:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3313:             s1 at precedent wave, to be dead a month before current
                   3314:             wave is equal to probability, being at state s1 at
                   3315:             precedent wave, to be dead at mont of the current
                   3316:             wave. Then the observed probability (that this person died)
                   3317:             is null according to current estimated parameter. In fact,
                   3318:             it should be very low but not zero otherwise the log go to
                   3319:             infinity.
                   3320:          */
1.183     brouard  3321: /* #ifdef INFINITYORIGINAL */
                   3322: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3323: /* #else */
                   3324: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3325: /*         lli=log(mytinydouble); */
                   3326: /*       else */
                   3327: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3328: /* #endif */
1.226     brouard  3329:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3330:          
1.226     brouard  3331:        } else if  ( s2==-1 ) { /* alive */
                   3332:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3333:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3334:          /*survp += out[s1][j]; */
                   3335:          lli= log(survp);
                   3336:        }
                   3337:        else if  (s2==-4) { 
                   3338:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3339:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3340:          lli= log(survp); 
                   3341:        } 
                   3342:        else if  (s2==-5) { 
                   3343:          for (j=1,survp=0. ; j<=2; j++)  
                   3344:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3345:          lli= log(survp); 
                   3346:        } 
                   3347:        else{
                   3348:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3349:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3350:        } 
                   3351:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3352:        /*if(lli ==000.0)*/
                   3353:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3354:        ipmx +=1;
                   3355:        sw += weight[i];
                   3356:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3357:        /* if (lli < log(mytinydouble)){ */
                   3358:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3359:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3360:        /* } */
                   3361:       } /* end of wave */
                   3362:     } /* end of individual */
                   3363:   }  else if(mle==2){
                   3364:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3365:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3366:       for(mi=1; mi<= wav[i]-1; mi++){
                   3367:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3368:          for (j=1;j<=nlstate+ndeath;j++){
                   3369:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3370:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3371:          }
                   3372:        for(d=0; d<=dh[mi][i]; d++){
                   3373:          newm=savm;
                   3374:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3375:          cov[2]=agexact;
                   3376:          if(nagesqr==1)
                   3377:            cov[3]= agexact*agexact;
                   3378:          for (kk=1; kk<=cptcovage;kk++) {
                   3379:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3380:          }
                   3381:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3382:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3383:          savm=oldm;
                   3384:          oldm=newm;
                   3385:        } /* end mult */
                   3386:       
                   3387:        s1=s[mw[mi][i]][i];
                   3388:        s2=s[mw[mi+1][i]][i];
                   3389:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3390:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3391:        ipmx +=1;
                   3392:        sw += weight[i];
                   3393:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3394:       } /* end of wave */
                   3395:     } /* end of individual */
                   3396:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3397:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3398:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3399:       for(mi=1; mi<= wav[i]-1; mi++){
                   3400:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3401:          for (j=1;j<=nlstate+ndeath;j++){
                   3402:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3403:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3404:          }
                   3405:        for(d=0; d<dh[mi][i]; d++){
                   3406:          newm=savm;
                   3407:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3408:          cov[2]=agexact;
                   3409:          if(nagesqr==1)
                   3410:            cov[3]= agexact*agexact;
                   3411:          for (kk=1; kk<=cptcovage;kk++) {
                   3412:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3413:          }
                   3414:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3415:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3416:          savm=oldm;
                   3417:          oldm=newm;
                   3418:        } /* end mult */
                   3419:       
                   3420:        s1=s[mw[mi][i]][i];
                   3421:        s2=s[mw[mi+1][i]][i];
                   3422:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3423:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3424:        ipmx +=1;
                   3425:        sw += weight[i];
                   3426:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3427:       } /* end of wave */
                   3428:     } /* end of individual */
                   3429:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3430:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3431:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3432:       for(mi=1; mi<= wav[i]-1; mi++){
                   3433:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3434:          for (j=1;j<=nlstate+ndeath;j++){
                   3435:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3436:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3437:          }
                   3438:        for(d=0; d<dh[mi][i]; d++){
                   3439:          newm=savm;
                   3440:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3441:          cov[2]=agexact;
                   3442:          if(nagesqr==1)
                   3443:            cov[3]= agexact*agexact;
                   3444:          for (kk=1; kk<=cptcovage;kk++) {
                   3445:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3446:          }
1.126     brouard  3447:        
1.226     brouard  3448:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3449:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3450:          savm=oldm;
                   3451:          oldm=newm;
                   3452:        } /* end mult */
                   3453:       
                   3454:        s1=s[mw[mi][i]][i];
                   3455:        s2=s[mw[mi+1][i]][i];
                   3456:        if( s2 > nlstate){ 
                   3457:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3458:        } else if  ( s2==-1 ) { /* alive */
                   3459:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3460:            survp += out[s1][j];
                   3461:          lli= log(survp);
                   3462:        }else{
                   3463:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3464:        }
                   3465:        ipmx +=1;
                   3466:        sw += weight[i];
                   3467:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3468: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3469:       } /* end of wave */
                   3470:     } /* end of individual */
                   3471:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3472:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3473:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3474:       for(mi=1; mi<= wav[i]-1; mi++){
                   3475:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3476:          for (j=1;j<=nlstate+ndeath;j++){
                   3477:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3478:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3479:          }
                   3480:        for(d=0; d<dh[mi][i]; d++){
                   3481:          newm=savm;
                   3482:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3483:          cov[2]=agexact;
                   3484:          if(nagesqr==1)
                   3485:            cov[3]= agexact*agexact;
                   3486:          for (kk=1; kk<=cptcovage;kk++) {
                   3487:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3488:          }
1.126     brouard  3489:        
1.226     brouard  3490:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3491:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3492:          savm=oldm;
                   3493:          oldm=newm;
                   3494:        } /* end mult */
                   3495:       
                   3496:        s1=s[mw[mi][i]][i];
                   3497:        s2=s[mw[mi+1][i]][i];
                   3498:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3499:        ipmx +=1;
                   3500:        sw += weight[i];
                   3501:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3502:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3503:       } /* end of wave */
                   3504:     } /* end of individual */
                   3505:   } /* End of if */
                   3506:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3507:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3508:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3509:   return -l;
1.126     brouard  3510: }
                   3511: 
                   3512: /*************** log-likelihood *************/
                   3513: double funcone( double *x)
                   3514: {
1.228     brouard  3515:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3516:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3517:   int ioffset=0;
1.131     brouard  3518:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3519:   double **out;
                   3520:   double lli; /* Individual log likelihood */
                   3521:   double llt;
                   3522:   int s1, s2;
1.228     brouard  3523:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3524: 
1.126     brouard  3525:   double bbh, survp;
1.187     brouard  3526:   double agexact;
1.214     brouard  3527:   double agebegin, ageend;
1.126     brouard  3528:   /*extern weight */
                   3529:   /* We are differentiating ll according to initial status */
                   3530:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3531:   /*for(i=1;i<imx;i++) 
                   3532:     printf(" %d\n",s[4][i]);
                   3533:   */
                   3534:   cov[1]=1.;
                   3535: 
                   3536:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3537:   ioffset=0;
                   3538:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3539:     /* ioffset=2+nagesqr+cptcovage; */
                   3540:     ioffset=2+nagesqr;
1.232     brouard  3541:     /* Fixed */
1.224     brouard  3542:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3543:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3544:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3545:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3546: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3547: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3548: /*    cov[2+6]=covar[2][i]; V2  */
                   3549: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3550: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3551: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3552: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3553: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3554: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3555:     }
1.232     brouard  3556:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3557:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3558:     /* } */
1.231     brouard  3559:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3560:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3561:     /* } */
1.225     brouard  3562:     
1.233     brouard  3563: 
                   3564:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3565:     /* Wave varying (but not age varying) */
                   3566:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3567:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3568:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3569:       }
1.232     brouard  3570:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3571:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3572:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3573:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3574:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3575:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3576:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3577:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3578:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3579:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3580:       /* } */
1.126     brouard  3581:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3582:        for (j=1;j<=nlstate+ndeath;j++){
                   3583:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3584:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3585:        }
1.214     brouard  3586:       
                   3587:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3588:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3589:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.242     brouard  3590:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3591:          and mw[mi+1][i]. dh depends on stepm.*/
                   3592:        newm=savm;
                   3593:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3594:        cov[2]=agexact;
                   3595:        if(nagesqr==1)
                   3596:          cov[3]= agexact*agexact;
                   3597:        for (kk=1; kk<=cptcovage;kk++) {
                   3598:          if(!FixedV[Tvar[Tage[kk]]])
                   3599:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3600:          else
                   3601:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3602:        }
                   3603:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3604:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3605:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3606:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3607:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3608:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3609:        savm=oldm;
                   3610:        oldm=newm;
1.126     brouard  3611:       } /* end mult */
                   3612:       
                   3613:       s1=s[mw[mi][i]][i];
                   3614:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3615:       /* if(s2==-1){ */
                   3616:       /*       printf(" s1=%d, s2=%d i=%d \n", s1, s2, i); */
                   3617:       /*       /\* exit(1); *\/ */
                   3618:       /* } */
1.126     brouard  3619:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3620:       /* bias is positive if real duration
                   3621:        * is higher than the multiple of stepm and negative otherwise.
                   3622:        */
                   3623:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3624:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3625:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3626:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3627:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3628:        lli= log(survp);
1.126     brouard  3629:       }else if (mle==1){
1.242     brouard  3630:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3631:       } else if(mle==2){
1.242     brouard  3632:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3633:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3634:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3635:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3636:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3637:       } else{  /* mle=0 back to 1 */
1.242     brouard  3638:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3639:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3640:       } /* End of if */
                   3641:       ipmx +=1;
                   3642:       sw += weight[i];
                   3643:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3644:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3645:       if(globpr){
1.242     brouard  3646:        fprintf(ficresilk,"%9ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3647:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3648:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
                   3649:                2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
                   3650:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3651:          llt +=ll[k]*gipmx/gsw;
                   3652:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3653:        }
                   3654:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3655:       }
1.232     brouard  3656:        } /* end of wave */
                   3657: } /* end of individual */
                   3658: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3659: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3660: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3661: if(globpr==0){ /* First time we count the contributions and weights */
                   3662:        gipmx=ipmx;
                   3663:        gsw=sw;
                   3664: }
                   3665: return -l;
1.126     brouard  3666: }
                   3667: 
                   3668: 
                   3669: /*************** function likelione ***********/
                   3670: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3671: {
                   3672:   /* This routine should help understanding what is done with 
                   3673:      the selection of individuals/waves and
                   3674:      to check the exact contribution to the likelihood.
                   3675:      Plotting could be done.
                   3676:    */
                   3677:   int k;
                   3678: 
                   3679:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3680:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3681:     strcat(fileresilk,fileresu);
1.126     brouard  3682:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3683:       printf("Problem with resultfile: %s\n", fileresilk);
                   3684:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3685:     }
1.214     brouard  3686:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3687:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3688:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3689:     for(k=1; k<=nlstate; k++) 
                   3690:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3691:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3692:   }
                   3693: 
                   3694:   *fretone=(*funcone)(p);
                   3695:   if(*globpri !=0){
                   3696:     fclose(ficresilk);
1.205     brouard  3697:     if (mle ==0)
                   3698:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3699:     else if(mle >=1)
                   3700:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3701:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3702:     
1.208     brouard  3703:       
                   3704:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3705:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3706: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3707:     }
1.207     brouard  3708:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3709: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3710:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3711: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3712:     fflush(fichtm);
1.205     brouard  3713:   }
1.126     brouard  3714:   return;
                   3715: }
                   3716: 
                   3717: 
                   3718: /*********** Maximum Likelihood Estimation ***************/
                   3719: 
                   3720: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3721: {
1.165     brouard  3722:   int i,j, iter=0;
1.126     brouard  3723:   double **xi;
                   3724:   double fret;
                   3725:   double fretone; /* Only one call to likelihood */
                   3726:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3727: 
                   3728: #ifdef NLOPT
                   3729:   int creturn;
                   3730:   nlopt_opt opt;
                   3731:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3732:   double *lb;
                   3733:   double minf; /* the minimum objective value, upon return */
                   3734:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3735:   myfunc_data dinst, *d = &dinst;
                   3736: #endif
                   3737: 
                   3738: 
1.126     brouard  3739:   xi=matrix(1,npar,1,npar);
                   3740:   for (i=1;i<=npar;i++)
                   3741:     for (j=1;j<=npar;j++)
                   3742:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3743:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3744:   strcpy(filerespow,"POW_"); 
1.126     brouard  3745:   strcat(filerespow,fileres);
                   3746:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3747:     printf("Problem with resultfile: %s\n", filerespow);
                   3748:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3749:   }
                   3750:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3751:   for (i=1;i<=nlstate;i++)
                   3752:     for(j=1;j<=nlstate+ndeath;j++)
                   3753:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3754:   fprintf(ficrespow,"\n");
1.162     brouard  3755: #ifdef POWELL
1.126     brouard  3756:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3757: #endif
1.126     brouard  3758: 
1.162     brouard  3759: #ifdef NLOPT
                   3760: #ifdef NEWUOA
                   3761:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3762: #else
                   3763:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3764: #endif
                   3765:   lb=vector(0,npar-1);
                   3766:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3767:   nlopt_set_lower_bounds(opt, lb);
                   3768:   nlopt_set_initial_step1(opt, 0.1);
                   3769:   
                   3770:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3771:   d->function = func;
                   3772:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3773:   nlopt_set_min_objective(opt, myfunc, d);
                   3774:   nlopt_set_xtol_rel(opt, ftol);
                   3775:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3776:     printf("nlopt failed! %d\n",creturn); 
                   3777:   }
                   3778:   else {
                   3779:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3780:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3781:     iter=1; /* not equal */
                   3782:   }
                   3783:   nlopt_destroy(opt);
                   3784: #endif
1.126     brouard  3785:   free_matrix(xi,1,npar,1,npar);
                   3786:   fclose(ficrespow);
1.203     brouard  3787:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3788:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3789:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3790: 
                   3791: }
                   3792: 
                   3793: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3794: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3795: {
                   3796:   double  **a,**y,*x,pd;
1.203     brouard  3797:   /* double **hess; */
1.164     brouard  3798:   int i, j;
1.126     brouard  3799:   int *indx;
                   3800: 
                   3801:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3802:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3803:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3804:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3805:   double gompertz(double p[]);
1.203     brouard  3806:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3807: 
                   3808:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3809:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3810:   for (i=1;i<=npar;i++){
1.203     brouard  3811:     printf("%d-",i);fflush(stdout);
                   3812:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3813:    
                   3814:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3815:     
                   3816:     /*  printf(" %f ",p[i]);
                   3817:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3818:   }
                   3819:   
                   3820:   for (i=1;i<=npar;i++) {
                   3821:     for (j=1;j<=npar;j++)  {
                   3822:       if (j>i) { 
1.203     brouard  3823:        printf(".%d-%d",i,j);fflush(stdout);
                   3824:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3825:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3826:        
                   3827:        hess[j][i]=hess[i][j];    
                   3828:        /*printf(" %lf ",hess[i][j]);*/
                   3829:       }
                   3830:     }
                   3831:   }
                   3832:   printf("\n");
                   3833:   fprintf(ficlog,"\n");
                   3834: 
                   3835:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3836:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3837:   
                   3838:   a=matrix(1,npar,1,npar);
                   3839:   y=matrix(1,npar,1,npar);
                   3840:   x=vector(1,npar);
                   3841:   indx=ivector(1,npar);
                   3842:   for (i=1;i<=npar;i++)
                   3843:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3844:   ludcmp(a,npar,indx,&pd);
                   3845: 
                   3846:   for (j=1;j<=npar;j++) {
                   3847:     for (i=1;i<=npar;i++) x[i]=0;
                   3848:     x[j]=1;
                   3849:     lubksb(a,npar,indx,x);
                   3850:     for (i=1;i<=npar;i++){ 
                   3851:       matcov[i][j]=x[i];
                   3852:     }
                   3853:   }
                   3854: 
                   3855:   printf("\n#Hessian matrix#\n");
                   3856:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   3857:   for (i=1;i<=npar;i++) { 
                   3858:     for (j=1;j<=npar;j++) { 
1.203     brouard  3859:       printf("%.6e ",hess[i][j]);
                   3860:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  3861:     }
                   3862:     printf("\n");
                   3863:     fprintf(ficlog,"\n");
                   3864:   }
                   3865: 
1.203     brouard  3866:   /* printf("\n#Covariance matrix#\n"); */
                   3867:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   3868:   /* for (i=1;i<=npar;i++) {  */
                   3869:   /*   for (j=1;j<=npar;j++) {  */
                   3870:   /*     printf("%.6e ",matcov[i][j]); */
                   3871:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   3872:   /*   } */
                   3873:   /*   printf("\n"); */
                   3874:   /*   fprintf(ficlog,"\n"); */
                   3875:   /* } */
                   3876: 
1.126     brouard  3877:   /* Recompute Inverse */
1.203     brouard  3878:   /* for (i=1;i<=npar;i++) */
                   3879:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   3880:   /* ludcmp(a,npar,indx,&pd); */
                   3881: 
                   3882:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   3883: 
                   3884:   /* for (j=1;j<=npar;j++) { */
                   3885:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   3886:   /*   x[j]=1; */
                   3887:   /*   lubksb(a,npar,indx,x); */
                   3888:   /*   for (i=1;i<=npar;i++){  */
                   3889:   /*     y[i][j]=x[i]; */
                   3890:   /*     printf("%.3e ",y[i][j]); */
                   3891:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   3892:   /*   } */
                   3893:   /*   printf("\n"); */
                   3894:   /*   fprintf(ficlog,"\n"); */
                   3895:   /* } */
                   3896: 
                   3897:   /* Verifying the inverse matrix */
                   3898: #ifdef DEBUGHESS
                   3899:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  3900: 
1.203     brouard  3901:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   3902:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  3903: 
                   3904:   for (j=1;j<=npar;j++) {
                   3905:     for (i=1;i<=npar;i++){ 
1.203     brouard  3906:       printf("%.2f ",y[i][j]);
                   3907:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  3908:     }
                   3909:     printf("\n");
                   3910:     fprintf(ficlog,"\n");
                   3911:   }
1.203     brouard  3912: #endif
1.126     brouard  3913: 
                   3914:   free_matrix(a,1,npar,1,npar);
                   3915:   free_matrix(y,1,npar,1,npar);
                   3916:   free_vector(x,1,npar);
                   3917:   free_ivector(indx,1,npar);
1.203     brouard  3918:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  3919: 
                   3920: 
                   3921: }
                   3922: 
                   3923: /*************** hessian matrix ****************/
                   3924: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  3925: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  3926:   int i;
                   3927:   int l=1, lmax=20;
1.203     brouard  3928:   double k1,k2, res, fx;
1.132     brouard  3929:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  3930:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   3931:   int k=0,kmax=10;
                   3932:   double l1;
                   3933: 
                   3934:   fx=func(x);
                   3935:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  3936:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  3937:     l1=pow(10,l);
                   3938:     delts=delt;
                   3939:     for(k=1 ; k <kmax; k=k+1){
                   3940:       delt = delta*(l1*k);
                   3941:       p2[theta]=x[theta] +delt;
1.145     brouard  3942:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  3943:       p2[theta]=x[theta]-delt;
                   3944:       k2=func(p2)-fx;
                   3945:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  3946:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  3947:       
1.203     brouard  3948: #ifdef DEBUGHESSII
1.126     brouard  3949:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3950:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3951: #endif
                   3952:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   3953:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   3954:        k=kmax;
                   3955:       }
                   3956:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  3957:        k=kmax; l=lmax*10;
1.126     brouard  3958:       }
                   3959:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   3960:        delts=delt;
                   3961:       }
1.203     brouard  3962:     } /* End loop k */
1.126     brouard  3963:   }
                   3964:   delti[theta]=delts;
                   3965:   return res; 
                   3966:   
                   3967: }
                   3968: 
1.203     brouard  3969: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  3970: {
                   3971:   int i;
1.164     brouard  3972:   int l=1, lmax=20;
1.126     brouard  3973:   double k1,k2,k3,k4,res,fx;
1.132     brouard  3974:   double p2[MAXPARM+1];
1.203     brouard  3975:   int k, kmax=1;
                   3976:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  3977: 
                   3978:   int firstime=0;
1.203     brouard  3979:   
1.126     brouard  3980:   fx=func(x);
1.203     brouard  3981:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  3982:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  3983:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   3984:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  3985:     k1=func(p2)-fx;
                   3986:   
1.203     brouard  3987:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   3988:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  3989:     k2=func(p2)-fx;
                   3990:   
1.203     brouard  3991:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   3992:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  3993:     k3=func(p2)-fx;
                   3994:   
1.203     brouard  3995:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   3996:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  3997:     k4=func(p2)-fx;
1.203     brouard  3998:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   3999:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4000:       firstime=1;
1.203     brouard  4001:       kmax=kmax+10;
1.208     brouard  4002:     }
                   4003:     if(kmax >=10 || firstime ==1){
1.218     brouard  4004:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you may increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4005:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you may increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4006:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4007:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4008:     }
                   4009: #ifdef DEBUGHESSIJ
                   4010:     v1=hess[thetai][thetai];
                   4011:     v2=hess[thetaj][thetaj];
                   4012:     cv12=res;
                   4013:     /* Computing eigen value of Hessian matrix */
                   4014:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4015:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4016:     if ((lc2 <0) || (lc1 <0) ){
                   4017:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4018:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4019:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4020:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4021:     }
1.126     brouard  4022: #endif
                   4023:   }
                   4024:   return res;
                   4025: }
                   4026: 
1.203     brouard  4027:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4028: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4029: /* { */
                   4030: /*   int i; */
                   4031: /*   int l=1, lmax=20; */
                   4032: /*   double k1,k2,k3,k4,res,fx; */
                   4033: /*   double p2[MAXPARM+1]; */
                   4034: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4035: /*   int k=0,kmax=10; */
                   4036: /*   double l1; */
                   4037:   
                   4038: /*   fx=func(x); */
                   4039: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4040: /*     l1=pow(10,l); */
                   4041: /*     delts=delt; */
                   4042: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4043: /*       delt = delti*(l1*k); */
                   4044: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4045: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4046: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4047: /*       k1=func(p2)-fx; */
                   4048:       
                   4049: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4050: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4051: /*       k2=func(p2)-fx; */
                   4052:       
                   4053: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4054: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4055: /*       k3=func(p2)-fx; */
                   4056:       
                   4057: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4058: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4059: /*       k4=func(p2)-fx; */
                   4060: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4061: /* #ifdef DEBUGHESSIJ */
                   4062: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4063: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4064: /* #endif */
                   4065: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4066: /*     k=kmax; */
                   4067: /*       } */
                   4068: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4069: /*     k=kmax; l=lmax*10; */
                   4070: /*       } */
                   4071: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4072: /*     delts=delt; */
                   4073: /*       } */
                   4074: /*     } /\* End loop k *\/ */
                   4075: /*   } */
                   4076: /*   delti[theta]=delts; */
                   4077: /*   return res;  */
                   4078: /* } */
                   4079: 
                   4080: 
1.126     brouard  4081: /************** Inverse of matrix **************/
                   4082: void ludcmp(double **a, int n, int *indx, double *d) 
                   4083: { 
                   4084:   int i,imax,j,k; 
                   4085:   double big,dum,sum,temp; 
                   4086:   double *vv; 
                   4087:  
                   4088:   vv=vector(1,n); 
                   4089:   *d=1.0; 
                   4090:   for (i=1;i<=n;i++) { 
                   4091:     big=0.0; 
                   4092:     for (j=1;j<=n;j++) 
                   4093:       if ((temp=fabs(a[i][j])) > big) big=temp; 
                   4094:     if (big == 0.0) nrerror("Singular matrix in routine ludcmp"); 
                   4095:     vv[i]=1.0/big; 
                   4096:   } 
                   4097:   for (j=1;j<=n;j++) { 
                   4098:     for (i=1;i<j;i++) { 
                   4099:       sum=a[i][j]; 
                   4100:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4101:       a[i][j]=sum; 
                   4102:     } 
                   4103:     big=0.0; 
                   4104:     for (i=j;i<=n;i++) { 
                   4105:       sum=a[i][j]; 
                   4106:       for (k=1;k<j;k++) 
                   4107:        sum -= a[i][k]*a[k][j]; 
                   4108:       a[i][j]=sum; 
                   4109:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4110:        big=dum; 
                   4111:        imax=i; 
                   4112:       } 
                   4113:     } 
                   4114:     if (j != imax) { 
                   4115:       for (k=1;k<=n;k++) { 
                   4116:        dum=a[imax][k]; 
                   4117:        a[imax][k]=a[j][k]; 
                   4118:        a[j][k]=dum; 
                   4119:       } 
                   4120:       *d = -(*d); 
                   4121:       vv[imax]=vv[j]; 
                   4122:     } 
                   4123:     indx[j]=imax; 
                   4124:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4125:     if (j != n) { 
                   4126:       dum=1.0/(a[j][j]); 
                   4127:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4128:     } 
                   4129:   } 
                   4130:   free_vector(vv,1,n);  /* Doesn't work */
                   4131: ;
                   4132: } 
                   4133: 
                   4134: void lubksb(double **a, int n, int *indx, double b[]) 
                   4135: { 
                   4136:   int i,ii=0,ip,j; 
                   4137:   double sum; 
                   4138:  
                   4139:   for (i=1;i<=n;i++) { 
                   4140:     ip=indx[i]; 
                   4141:     sum=b[ip]; 
                   4142:     b[ip]=b[i]; 
                   4143:     if (ii) 
                   4144:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4145:     else if (sum) ii=i; 
                   4146:     b[i]=sum; 
                   4147:   } 
                   4148:   for (i=n;i>=1;i--) { 
                   4149:     sum=b[i]; 
                   4150:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4151:     b[i]=sum/a[i][i]; 
                   4152:   } 
                   4153: } 
                   4154: 
                   4155: void pstamp(FILE *fichier)
                   4156: {
1.196     brouard  4157:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4158: }
                   4159: 
                   4160: /************ Frequencies ********************/
1.226     brouard  4161: void  freqsummary(char fileres[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
                   4162:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4163:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
                   4164: {  /* Some frequencies */
                   4165:   
1.227     brouard  4166:   int i, m, jk, j1, bool, z1,j, k, iv;
1.226     brouard  4167:   int iind=0, iage=0;
                   4168:   int mi; /* Effective wave */
                   4169:   int first;
                   4170:   double ***freq; /* Frequencies */
                   4171:   double *meanq;
                   4172:   double **meanqt;
                   4173:   double *pp, **prop, *posprop, *pospropt;
                   4174:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4175:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4176:   double agebegin, ageend;
                   4177:     
                   4178:   pp=vector(1,nlstate);
                   4179:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+3+AGEMARGE); 
                   4180:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4181:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4182:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4183:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4184:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4185:   strcpy(fileresp,"P_");
                   4186:   strcat(fileresp,fileresu);
                   4187:   /*strcat(fileresphtm,fileresu);*/
                   4188:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4189:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4190:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4191:     exit(0);
                   4192:   }
1.240     brouard  4193:   
1.226     brouard  4194:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4195:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4196:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4197:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4198:     fflush(ficlog);
                   4199:     exit(70); 
                   4200:   }
                   4201:   else{
                   4202:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4203: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4204: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4205:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4206:   }
1.237     brouard  4207:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4208:   
1.226     brouard  4209:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4210:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4211:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4212:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4213:     fflush(ficlog);
                   4214:     exit(70); 
1.240     brouard  4215:   } else{
1.226     brouard  4216:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4217: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4218: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4219:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4220:   }
1.240     brouard  4221:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4222:   
1.226     brouard  4223:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+3+AGEMARGE);
                   4224:   j1=0;
1.126     brouard  4225:   
1.227     brouard  4226:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4227:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4228:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4229:   
1.226     brouard  4230:   first=1;
1.240     brouard  4231:   
1.226     brouard  4232:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4233:      reference=low_education V1=0,V2=0
                   4234:      med_educ                V1=1 V2=0, 
                   4235:      high_educ               V1=0 V2=1
                   4236:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4237:   */
1.240     brouard  4238:   
1.227     brouard  4239:   for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on covariates combination in order of model, excluding quantitatives V4=0, V3=0 for example, fixed or varying covariates */
1.226     brouard  4240:     posproptt=0.;
                   4241:     /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4242:       scanf("%d", i);*/
                   4243:     for (i=-5; i<=nlstate+ndeath; i++)  
                   4244:       for (jk=-5; jk<=nlstate+ndeath; jk++)  
1.240     brouard  4245:        for(m=iagemin; m <= iagemax+3; m++)
                   4246:          freq[i][jk][m]=0;
                   4247:     
1.226     brouard  4248:     for (i=1; i<=nlstate; i++)  {
                   4249:       for(m=iagemin; m <= iagemax+3; m++)
1.240     brouard  4250:        prop[i][m]=0;
1.226     brouard  4251:       posprop[i]=0;
                   4252:       pospropt[i]=0;
                   4253:     }
1.227     brouard  4254:     /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4255:     /*   meanq[z1]+=0.; */
                   4256:     /*   for(m=1;m<=lastpass;m++){ */
                   4257:     /*         meanqt[m][z1]=0.; */
                   4258:     /*   } */
                   4259:     /* } */
1.240     brouard  4260:     
1.226     brouard  4261:     dateintsum=0;
                   4262:     k2cpt=0;
1.227     brouard  4263:     /* For that combination of covariate j1, we count and print the frequencies in one pass */
1.226     brouard  4264:     for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4265:       bool=1;
1.227     brouard  4266:       if(anyvaryingduminmodel==0){ /* If All fixed covariates */
1.234     brouard  4267:        if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
1.227     brouard  4268:          /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4269:          /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4270:          /* } */
1.234     brouard  4271:          for (z1=1; z1<=cptcoveff; z1++) {  
                   4272:            /* if(Tvaraff[z1] ==-20){ */
                   4273:            /*   /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4274:            /* }else  if(Tvaraff[z1] ==-10){ */
                   4275:            /*   /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4276:            /* }else  */
                   4277:            if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){
                   4278:              /* Tests if this individual iind responded to j1 (V4=1 V3=0) */
                   4279:              bool=0;
                   4280:              /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4281:                 bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4282:                 j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4283:              /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4284:            } /* Onlyf fixed */
                   4285:          } /* end z1 */
                   4286:        } /* cptcovn > 0 */
1.227     brouard  4287:       } /* end any */
                   4288:       if (bool==1){ /* We selected an individual iind satisfying combination j1 or all fixed */
1.234     brouard  4289:        /* for(m=firstpass; m<=lastpass; m++){ */
                   4290:        for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4291:          m=mw[mi][iind];
                   4292:          if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4293:            for (z1=1; z1<=cptcoveff; z1++) {
                   4294:              if( Fixed[Tmodelind[z1]]==1){
                   4295:                iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4296:                if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4297:                  bool=0;
                   4298:              }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4299:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4300:                  bool=0;
                   4301:                }
                   4302:              }
                   4303:            }
                   4304:          }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4305:          /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4306:          if(bool==1){
                   4307:            /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4308:               and mw[mi+1][iind]. dh depends on stepm. */
                   4309:            agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4310:            ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4311:            if(m >=firstpass && m <=lastpass){
                   4312:              k2=anint[m][iind]+(mint[m][iind]/12.);
                   4313:              /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4314:              if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4315:              if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4316:              if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4317:                prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4318:              if (m<lastpass) {
                   4319:                /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4320:                /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4321:                if(s[m][iind]==-1)
                   4322:                  printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4323:                freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4324:                /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4325:                freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
                   4326:              }
                   4327:            } /* end if between passes */  
                   4328:            if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99)) {
                   4329:              dateintsum=dateintsum+k2;
                   4330:              k2cpt++;
                   4331:              /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
                   4332:            }
                   4333:          } /* end bool 2 */
                   4334:        } /* end m */
1.226     brouard  4335:       } /* end bool */
                   4336:     } /* end iind = 1 to imx */
                   4337:     /* prop[s][age] is feeded for any initial and valid live state as well as
                   4338:        freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
1.240     brouard  4339:     
                   4340:     
1.226     brouard  4341:     /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
                   4342:     pstamp(ficresp);
1.240     brouard  4343:     if  (cptcoveff>0){
1.226     brouard  4344:       fprintf(ficresp, "\n#********** Variable "); 
                   4345:       fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4346:       fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
1.240     brouard  4347:       fprintf(ficlog, "\n#********** Variable "); 
1.227     brouard  4348:       for (z1=1; z1<=cptcoveff; z1++){
1.240     brouard  4349:        if(DummyV[z1]){
                   4350:          fprintf(ficresp, "V%d (fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4351:          fprintf(ficresphtm, "V%d (fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4352:          fprintf(ficresphtmfr, "V%d (fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4353:          fprintf(ficlog, "V%d (fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4354:        }else{
                   4355:          fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4356:          fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4357:          fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4358:          fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4359:        }
1.226     brouard  4360:       }
                   4361:       fprintf(ficresp, "**********\n#");
                   4362:       fprintf(ficresphtm, "**********</h3>\n");
                   4363:       fprintf(ficresphtmfr, "**********</h3>\n");
                   4364:       fprintf(ficlog, "**********\n");
                   4365:     }
                   4366:     fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
                   4367:     for(i=1; i<=nlstate;i++) {
1.240     brouard  4368:       fprintf(ficresp, " Age Prev(%d)  N(%d)  N  ",i,i);
1.226     brouard  4369:       fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4370:     }
                   4371:     fprintf(ficresp, "\n");
                   4372:     fprintf(ficresphtm, "\n");
1.240     brouard  4373:     
1.226     brouard  4374:     /* Header of frequency table by age */
                   4375:     fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4376:     fprintf(ficresphtmfr,"<th>Age</th> ");
                   4377:     for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4378:       for(m=-1; m <=nlstate+ndeath; m++){
1.234     brouard  4379:        if(jk!=0 && m!=0)
                   4380:          fprintf(ficresphtmfr,"<th>%d%d</th> ",jk,m);
1.226     brouard  4381:       }
                   4382:     }
                   4383:     fprintf(ficresphtmfr, "\n");
1.240     brouard  4384:     
1.226     brouard  4385:     /* For each age */
                   4386:     for(iage=iagemin; iage <= iagemax+3; iage++){
                   4387:       fprintf(ficresphtm,"<tr>");
                   4388:       if(iage==iagemax+1){
1.240     brouard  4389:        fprintf(ficlog,"1");
                   4390:        fprintf(ficresphtmfr,"<tr><th>0</th> ");
1.226     brouard  4391:       }else if(iage==iagemax+2){
1.240     brouard  4392:        fprintf(ficlog,"0");
                   4393:        fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
1.226     brouard  4394:       }else if(iage==iagemax+3){
1.240     brouard  4395:        fprintf(ficlog,"Total");
                   4396:        fprintf(ficresphtmfr,"<tr><th>Total</th> ");
1.226     brouard  4397:       }else{
1.240     brouard  4398:        if(first==1){
                   4399:          first=0;
                   4400:          printf("See log file for details...\n");
                   4401:        }
                   4402:        fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4403:        fprintf(ficlog,"Age %d", iage);
1.226     brouard  4404:       }
                   4405:       for(jk=1; jk <=nlstate ; jk++){
1.240     brouard  4406:        for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
                   4407:          pp[jk] += freq[jk][m][iage]; 
1.226     brouard  4408:       }
                   4409:       for(jk=1; jk <=nlstate ; jk++){
1.240     brouard  4410:        for(m=-1, pos=0; m <=0 ; m++)
                   4411:          pos += freq[jk][m][iage];
                   4412:        if(pp[jk]>=1.e-10){
                   4413:          if(first==1){
                   4414:            printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4415:          }
                   4416:          fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4417:        }else{
                   4418:          if(first==1)
                   4419:            printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
                   4420:          fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
                   4421:        }
1.226     brouard  4422:       }
1.240     brouard  4423:       
1.226     brouard  4424:       for(jk=1; jk <=nlstate ; jk++){ 
1.240     brouard  4425:        /* posprop[jk]=0; */
                   4426:        for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4427:          pp[jk] += freq[jk][m][iage];
1.226     brouard  4428:       }        /* pp[jk] is the total number of transitions starting from state jk and any ending status until this age */
1.240     brouard  4429:       
1.226     brouard  4430:       for(jk=1,pos=0, pospropta=0.; jk <=nlstate ; jk++){
1.240     brouard  4431:        pos += pp[jk]; /* pos is the total number of transitions until this age */
                   4432:        posprop[jk] += prop[jk][iage]; /* prop is the number of transitions from a live state
                   4433:                                          from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4434:        pospropta += prop[jk][iage]; /* prop is the number of transitions from a live state
                   4435:                                        from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
1.226     brouard  4436:       }
                   4437:       for(jk=1; jk <=nlstate ; jk++){
1.240     brouard  4438:        if(pos>=1.e-5){
                   4439:          if(first==1)
                   4440:            printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4441:          fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4442:        }else{
                   4443:          if(first==1)
                   4444:            printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4445:          fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4446:        }
                   4447:        if( iage <= iagemax){
                   4448:          if(pos>=1.e-5){
                   4449:            fprintf(ficresp," %d %.5f %.0f %.0f",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4450:            fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4451:            /*probs[iage][jk][j1]= pp[jk]/pos;*/
                   4452:            /*printf("\niage=%d jk=%d j1=%d %.5f %.0f %.0f %f",iage,jk,j1,pp[jk]/pos, pp[jk],pos,probs[iage][jk][j1]);*/
                   4453:          }
                   4454:          else{
                   4455:            fprintf(ficresp," %d NaNq %.0f %.0f",iage,prop[jk][iage],pospropta);
                   4456:            fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[jk][iage],pospropta);
                   4457:          }
                   4458:        }
                   4459:        pospropt[jk] +=posprop[jk];
1.226     brouard  4460:       } /* end loop jk */
                   4461:       /* pospropt=0.; */
                   4462:       for(jk=-1; jk <=nlstate+ndeath; jk++){
1.240     brouard  4463:        for(m=-1; m <=nlstate+ndeath; m++){
                   4464:          if(freq[jk][m][iage] !=0 ) { /* minimizing output */
                   4465:            if(first==1){
                   4466:              printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4467:            }
                   4468:            fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4469:          }
                   4470:          if(jk!=0 && m!=0)
                   4471:            fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[jk][m][iage]);
                   4472:        }
1.226     brouard  4473:       } /* end loop jk */
                   4474:       posproptt=0.; 
                   4475:       for(jk=1; jk <=nlstate; jk++){
1.240     brouard  4476:        posproptt += pospropt[jk];
1.226     brouard  4477:       }
                   4478:       fprintf(ficresphtmfr,"</tr>\n ");
                   4479:       if(iage <= iagemax){
1.240     brouard  4480:        fprintf(ficresp,"\n");
                   4481:        fprintf(ficresphtm,"</tr>\n");
1.226     brouard  4482:       }
                   4483:       if(first==1)
1.240     brouard  4484:        printf("Others in log...\n");
1.226     brouard  4485:       fprintf(ficlog,"\n");
                   4486:     } /* end loop age iage */
                   4487:     fprintf(ficresphtm,"<tr><th>Tot</th>");
                   4488:     for(jk=1; jk <=nlstate ; jk++){
                   4489:       if(posproptt < 1.e-5){
1.240     brouard  4490:        fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[jk],posproptt);   
1.226     brouard  4491:       }else{
1.240     brouard  4492:        fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[jk]/posproptt,pospropt[jk],posproptt);    
1.226     brouard  4493:       }
                   4494:     }
                   4495:     fprintf(ficresphtm,"</tr>\n");
                   4496:     fprintf(ficresphtm,"</table>\n");
                   4497:     fprintf(ficresphtmfr,"</table>\n");
                   4498:     if(posproptt < 1.e-5){
                   4499:       fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4500:       fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4501:       fprintf(ficres,"\n  This combination (%d) is not valid and no result will be produced\n\n",j1);
                   4502:       invalidvarcomb[j1]=1;
                   4503:     }else{
                   4504:       fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4505:       invalidvarcomb[j1]=0;
                   4506:     }
                   4507:     fprintf(ficresphtmfr,"</table>\n");
                   4508:   } /* end selected combination of covariate j1 */
                   4509:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4510:   
1.226     brouard  4511:   fclose(ficresp);
                   4512:   fclose(ficresphtm);
                   4513:   fclose(ficresphtmfr);
                   4514:   free_vector(meanq,1,nqfveff);
                   4515:   free_matrix(meanqt,1,lastpass,1,nqtveff);
                   4516:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+3+AGEMARGE);
                   4517:   free_vector(pospropt,1,nlstate);
                   4518:   free_vector(posprop,1,nlstate);
                   4519:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+3+AGEMARGE);
                   4520:   free_vector(pp,1,nlstate);
                   4521:   /* End of freqsummary */
                   4522: }
1.126     brouard  4523: 
                   4524: /************ Prevalence ********************/
1.227     brouard  4525: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4526: {  
                   4527:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4528:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4529:      We still use firstpass and lastpass as another selection.
                   4530:   */
1.126     brouard  4531:  
1.227     brouard  4532:   int i, m, jk, j1, bool, z1,j, iv;
                   4533:   int mi; /* Effective wave */
                   4534:   int iage;
                   4535:   double agebegin, ageend;
                   4536: 
                   4537:   double **prop;
                   4538:   double posprop; 
                   4539:   double  y2; /* in fractional years */
                   4540:   int iagemin, iagemax;
                   4541:   int first; /** to stop verbosity which is redirected to log file */
                   4542: 
                   4543:   iagemin= (int) agemin;
                   4544:   iagemax= (int) agemax;
                   4545:   /*pp=vector(1,nlstate);*/
                   4546:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+3+AGEMARGE); 
                   4547:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4548:   j1=0;
1.222     brouard  4549:   
1.227     brouard  4550:   /*j=cptcoveff;*/
                   4551:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4552:   
1.227     brouard  4553:   first=1;
                   4554:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4555:     for (i=1; i<=nlstate; i++)  
                   4556:       for(iage=iagemin-AGEMARGE; iage <= iagemax+3+AGEMARGE; iage++)
                   4557:        prop[i][iage]=0.0;
                   4558:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4559:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4560:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4561:     
                   4562:     for (i=1; i<=imx; i++) { /* Each individual */
                   4563:       bool=1;
                   4564:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4565:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4566:        m=mw[mi][i];
                   4567:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4568:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4569:        for (z1=1; z1<=cptcoveff; z1++){
                   4570:          if( Fixed[Tmodelind[z1]]==1){
                   4571:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4572:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4573:              bool=0;
                   4574:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4575:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4576:              bool=0;
                   4577:            }
                   4578:        }
                   4579:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4580:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4581:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4582:          if(m >=firstpass && m <=lastpass){
                   4583:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4584:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4585:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   4586:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
                   4587:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+3+AGEMARGE){
                   4588:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   4589:                exit(1);
                   4590:              }
                   4591:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   4592:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   4593:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   4594:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   4595:              } /* end valid statuses */ 
                   4596:            } /* end selection of dates */
                   4597:          } /* end selection of waves */
                   4598:        } /* end bool */
                   4599:       } /* end wave */
                   4600:     } /* end individual */
                   4601:     for(i=iagemin; i <= iagemax+3; i++){  
                   4602:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   4603:        posprop += prop[jk][i]; 
                   4604:       } 
                   4605:       
                   4606:       for(jk=1; jk <=nlstate ; jk++){      
                   4607:        if( i <=  iagemax){ 
                   4608:          if(posprop>=1.e-5){ 
                   4609:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   4610:          } else{
                   4611:            if(first==1){
                   4612:              first=0;
                   4613:              printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,j1,probs[i][jk][j1]);
                   4614:            }
                   4615:          }
                   4616:        } 
                   4617:       }/* end jk */ 
                   4618:     }/* end i */ 
1.222     brouard  4619:      /*} *//* end i1 */
1.227     brouard  4620:   } /* end j1 */
1.222     brouard  4621:   
1.227     brouard  4622:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   4623:   /*free_vector(pp,1,nlstate);*/
                   4624:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+3+AGEMARGE);
                   4625: }  /* End of prevalence */
1.126     brouard  4626: 
                   4627: /************* Waves Concatenation ***************/
                   4628: 
                   4629: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   4630: {
                   4631:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   4632:      Death is a valid wave (if date is known).
                   4633:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   4634:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4635:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  4636:   */
1.126     brouard  4637: 
1.224     brouard  4638:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  4639:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   4640:      double sum=0., jmean=0.;*/
1.224     brouard  4641:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  4642:   int j, k=0,jk, ju, jl;
                   4643:   double sum=0.;
                   4644:   first=0;
1.214     brouard  4645:   firstwo=0;
1.217     brouard  4646:   firsthree=0;
1.218     brouard  4647:   firstfour=0;
1.164     brouard  4648:   jmin=100000;
1.126     brouard  4649:   jmax=-1;
                   4650:   jmean=0.;
1.224     brouard  4651: 
                   4652: /* Treating live states */
1.214     brouard  4653:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  4654:     mi=0;  /* First valid wave */
1.227     brouard  4655:     mli=0; /* Last valid wave */
1.126     brouard  4656:     m=firstpass;
1.214     brouard  4657:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  4658:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   4659:        mli=m-1;/* mw[++mi][i]=m-1; */
                   4660:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   4661:        mw[++mi][i]=m;
                   4662:        mli=m;
1.224     brouard  4663:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   4664:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  4665:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  4666:       }
1.227     brouard  4667:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  4668: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  4669:        break;
1.224     brouard  4670: #else
1.227     brouard  4671:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   4672:          if(firsthree == 0){
                   4673:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4674:            firsthree=1;
                   4675:          }
                   4676:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4677:          mw[++mi][i]=m;
                   4678:          mli=m;
                   4679:        }
                   4680:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   4681:          nbwarn++;
                   4682:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   4683:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4684:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4685:          }
                   4686:          break;
                   4687:        }
                   4688:        break;
1.224     brouard  4689: #endif
1.227     brouard  4690:       }/* End m >= lastpass */
1.126     brouard  4691:     }/* end while */
1.224     brouard  4692: 
1.227     brouard  4693:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  4694:     /* After last pass */
1.224     brouard  4695: /* Treating death states */
1.214     brouard  4696:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  4697:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   4698:       /* } */
1.126     brouard  4699:       mi++;    /* Death is another wave */
                   4700:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  4701:       /* Only death is a correct wave */
1.126     brouard  4702:       mw[mi][i]=m;
1.224     brouard  4703:     }
                   4704: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.227     brouard  4705:     else if ((int) andc[i] != 9999) { /* Status is negative. A death occured after lastpass, we can't take it into account because of potential bias */
1.216     brouard  4706:       /* m++; */
                   4707:       /* mi++; */
                   4708:       /* s[m][i]=nlstate+1;  /\* We are setting the status to the last of non live state *\/ */
                   4709:       /* mw[mi][i]=m; */
1.218     brouard  4710:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  4711:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   4712:          nbwarn++;
                   4713:          if(firstfiv==0){
                   4714:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4715:            firstfiv=1;
                   4716:          }else{
                   4717:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4718:          }
                   4719:        }else{ /* Death occured afer last wave potential bias */
                   4720:          nberr++;
                   4721:          if(firstwo==0){
                   4722:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4723:            firstwo=1;
                   4724:          }
                   4725:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4726:        }
1.218     brouard  4727:       }else{ /* end date of interview is known */
1.227     brouard  4728:        /* death is known but not confirmed by death status at any wave */
                   4729:        if(firstfour==0){
                   4730:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4731:          firstfour=1;
                   4732:        }
                   4733:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  4734:       }
1.224     brouard  4735:     } /* end if date of death is known */
                   4736: #endif
                   4737:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   4738:     /* wav[i]=mw[mi][i]; */
1.126     brouard  4739:     if(mi==0){
                   4740:       nbwarn++;
                   4741:       if(first==0){
1.227     brouard  4742:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   4743:        first=1;
1.126     brouard  4744:       }
                   4745:       if(first==1){
1.227     brouard  4746:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  4747:       }
                   4748:     } /* end mi==0 */
                   4749:   } /* End individuals */
1.214     brouard  4750:   /* wav and mw are no more changed */
1.223     brouard  4751:        
1.214     brouard  4752:   
1.126     brouard  4753:   for(i=1; i<=imx; i++){
                   4754:     for(mi=1; mi<wav[i];mi++){
                   4755:       if (stepm <=0)
1.227     brouard  4756:        dh[mi][i]=1;
1.126     brouard  4757:       else{
1.227     brouard  4758:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death */
                   4759:          if (agedc[i] < 2*AGESUP) {
                   4760:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   4761:            if(j==0) j=1;  /* Survives at least one month after exam */
                   4762:            else if(j<0){
                   4763:              nberr++;
                   4764:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4765:              j=1; /* Temporary Dangerous patch */
                   4766:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   4767:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4768:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   4769:            }
                   4770:            k=k+1;
                   4771:            if (j >= jmax){
                   4772:              jmax=j;
                   4773:              ijmax=i;
                   4774:            }
                   4775:            if (j <= jmin){
                   4776:              jmin=j;
                   4777:              ijmin=i;
                   4778:            }
                   4779:            sum=sum+j;
                   4780:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   4781:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   4782:          }
                   4783:        }
                   4784:        else{
                   4785:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  4786: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  4787:                                        
1.227     brouard  4788:          k=k+1;
                   4789:          if (j >= jmax) {
                   4790:            jmax=j;
                   4791:            ijmax=i;
                   4792:          }
                   4793:          else if (j <= jmin){
                   4794:            jmin=j;
                   4795:            ijmin=i;
                   4796:          }
                   4797:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   4798:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   4799:          if(j<0){
                   4800:            nberr++;
                   4801:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4802:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4803:          }
                   4804:          sum=sum+j;
                   4805:        }
                   4806:        jk= j/stepm;
                   4807:        jl= j -jk*stepm;
                   4808:        ju= j -(jk+1)*stepm;
                   4809:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   4810:          if(jl==0){
                   4811:            dh[mi][i]=jk;
                   4812:            bh[mi][i]=0;
                   4813:          }else{ /* We want a negative bias in order to only have interpolation ie
                   4814:                  * to avoid the price of an extra matrix product in likelihood */
                   4815:            dh[mi][i]=jk+1;
                   4816:            bh[mi][i]=ju;
                   4817:          }
                   4818:        }else{
                   4819:          if(jl <= -ju){
                   4820:            dh[mi][i]=jk;
                   4821:            bh[mi][i]=jl;       /* bias is positive if real duration
                   4822:                                 * is higher than the multiple of stepm and negative otherwise.
                   4823:                                 */
                   4824:          }
                   4825:          else{
                   4826:            dh[mi][i]=jk+1;
                   4827:            bh[mi][i]=ju;
                   4828:          }
                   4829:          if(dh[mi][i]==0){
                   4830:            dh[mi][i]=1; /* At least one step */
                   4831:            bh[mi][i]=ju; /* At least one step */
                   4832:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   4833:          }
                   4834:        } /* end if mle */
1.126     brouard  4835:       }
                   4836:     } /* end wave */
                   4837:   }
                   4838:   jmean=sum/k;
                   4839:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  4840:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  4841: }
1.126     brouard  4842: 
                   4843: /*********** Tricode ****************************/
1.220     brouard  4844:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  4845:  {
                   4846:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   4847:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   4848:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   4849:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   4850:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   4851:     */
1.130     brouard  4852: 
1.242     brouard  4853:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   4854:    int modmaxcovj=0; /* Modality max of covariates j */
                   4855:    int cptcode=0; /* Modality max of covariates j */
                   4856:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  4857: 
                   4858: 
1.242     brouard  4859:    /* cptcoveff=0;  */
                   4860:    /* *cptcov=0; */
1.126     brouard  4861:  
1.242     brouard  4862:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  4863: 
1.242     brouard  4864:    /* Loop on covariates without age and products and no quantitative variable */
                   4865:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   4866:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   4867:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   4868:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   4869:        switch(Fixed[k]) {
                   4870:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   4871:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   4872:           ij=(int)(covar[Tvar[k]][i]);
                   4873:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   4874:            * If product of Vn*Vm, still boolean *:
                   4875:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   4876:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   4877:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   4878:              modality of the nth covariate of individual i. */
                   4879:           if (ij > modmaxcovj)
                   4880:             modmaxcovj=ij; 
                   4881:           else if (ij < modmincovj) 
                   4882:             modmincovj=ij; 
                   4883:           if ((ij < -1) && (ij > NCOVMAX)){
                   4884:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   4885:             exit(1);
                   4886:           }else
                   4887:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   4888:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   4889:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   4890:           /* getting the maximum value of the modality of the covariate
                   4891:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   4892:              female ies 1, then modmaxcovj=1.
                   4893:           */
                   4894:         } /* end for loop on individuals i */
                   4895:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   4896:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   4897:         cptcode=modmaxcovj;
                   4898:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   4899:         /*for (i=0; i<=cptcode; i++) {*/
                   4900:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   4901:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   4902:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   4903:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   4904:             if( j != -1){
                   4905:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   4906:                                  covariate for which somebody answered excluding 
                   4907:                                  undefined. Usually 2: 0 and 1. */
                   4908:             }
                   4909:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   4910:                                     covariate for which somebody answered including 
                   4911:                                     undefined. Usually 3: -1, 0 and 1. */
                   4912:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   4913:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   4914:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  4915:                        
1.242     brouard  4916:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   4917:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   4918:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   4919:         /* modmincovj=3; modmaxcovj = 7; */
                   4920:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   4921:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   4922:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   4923:         /* nbcode[Tvar[j]][ij]=k; */
                   4924:         /* nbcode[Tvar[j]][1]=0; */
                   4925:         /* nbcode[Tvar[j]][2]=1; */
                   4926:         /* nbcode[Tvar[j]][3]=2; */
                   4927:         /* To be continued (not working yet). */
                   4928:         ij=0; /* ij is similar to i but can jump over null modalities */
                   4929:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   4930:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   4931:             break;
                   4932:           }
                   4933:           ij++;
                   4934:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   4935:           cptcode = ij; /* New max modality for covar j */
                   4936:         } /* end of loop on modality i=-1 to 1 or more */
                   4937:         break;
                   4938:        case 1: /* Testing on varying covariate, could be simple and
                   4939:                * should look at waves or product of fixed *
                   4940:                * varying. No time to test -1, assuming 0 and 1 only */
                   4941:         ij=0;
                   4942:         for(i=0; i<=1;i++){
                   4943:           nbcode[Tvar[k]][++ij]=i;
                   4944:         }
                   4945:         break;
                   4946:        default:
                   4947:         break;
                   4948:        } /* end switch */
                   4949:      } /* end dummy test */
                   4950:     
                   4951:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   4952:      /*        /\*recode from 0 *\/ */
                   4953:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   4954:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   4955:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   4956:      /*        } */
                   4957:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   4958:      /*        if (ij > ncodemax[j]) { */
                   4959:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   4960:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   4961:      /*          break; */
                   4962:      /*        } */
                   4963:      /*   }  /\* end of loop on modality k *\/ */
                   4964:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   4965:   
                   4966:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   4967:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   4968:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   4969:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   4970:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   4971:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   4972:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   4973:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   4974:   
                   4975:    ij=0;
                   4976:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   4977:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   4978:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   4979:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   4980:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   4981:        /* If product not in single variable we don't print results */
                   4982:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   4983:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   4984:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   4985:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   4986:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   4987:        if(Fixed[k]!=0)
                   4988:         anyvaryingduminmodel=1;
                   4989:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   4990:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   4991:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   4992:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   4993:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   4994:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   4995:      } 
                   4996:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   4997:    /* ij--; */
                   4998:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   4999:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5000:                * because they can be excluded from the model and real
                   5001:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5002:    for(j=ij+1; j<= cptcovt; j++){
                   5003:      Tvaraff[j]=0;
                   5004:      Tmodelind[j]=0;
                   5005:    }
                   5006:    for(j=ntveff+1; j<= cptcovt; j++){
                   5007:      TmodelInvind[j]=0;
                   5008:    }
                   5009:    /* To be sorted */
                   5010:    ;
                   5011:  }
1.126     brouard  5012: 
1.145     brouard  5013: 
1.126     brouard  5014: /*********** Health Expectancies ****************/
                   5015: 
1.235     brouard  5016:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5017: 
                   5018: {
                   5019:   /* Health expectancies, no variances */
1.164     brouard  5020:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5021:   int nhstepma, nstepma; /* Decreasing with age */
                   5022:   double age, agelim, hf;
                   5023:   double ***p3mat;
                   5024:   double eip;
                   5025: 
1.238     brouard  5026:   /* pstamp(ficreseij); */
1.126     brouard  5027:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5028:   fprintf(ficreseij,"# Age");
                   5029:   for(i=1; i<=nlstate;i++){
                   5030:     for(j=1; j<=nlstate;j++){
                   5031:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5032:     }
                   5033:     fprintf(ficreseij," e%1d. ",i);
                   5034:   }
                   5035:   fprintf(ficreseij,"\n");
                   5036: 
                   5037:   
                   5038:   if(estepm < stepm){
                   5039:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5040:   }
                   5041:   else  hstepm=estepm;   
                   5042:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5043:    * This is mainly to measure the difference between two models: for example
                   5044:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5045:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5046:    * progression in between and thus overestimating or underestimating according
                   5047:    * to the curvature of the survival function. If, for the same date, we 
                   5048:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5049:    * to compare the new estimate of Life expectancy with the same linear 
                   5050:    * hypothesis. A more precise result, taking into account a more precise
                   5051:    * curvature will be obtained if estepm is as small as stepm. */
                   5052: 
                   5053:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5054:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5055:      nhstepm is the number of hstepm from age to agelim 
                   5056:      nstepm is the number of stepm from age to agelin. 
                   5057:      Look at hpijx to understand the reason of that which relies in memory size
                   5058:      and note for a fixed period like estepm months */
                   5059:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5060:      survival function given by stepm (the optimization length). Unfortunately it
                   5061:      means that if the survival funtion is printed only each two years of age and if
                   5062:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5063:      results. So we changed our mind and took the option of the best precision.
                   5064:   */
                   5065:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5066: 
                   5067:   agelim=AGESUP;
                   5068:   /* If stepm=6 months */
                   5069:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5070:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5071:     
                   5072: /* nhstepm age range expressed in number of stepm */
                   5073:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5074:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5075:   /* if (stepm >= YEARM) hstepm=1;*/
                   5076:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5077:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5078: 
                   5079:   for (age=bage; age<=fage; age ++){ 
                   5080:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5081:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5082:     /* if (stepm >= YEARM) hstepm=1;*/
                   5083:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5084: 
                   5085:     /* If stepm=6 months */
                   5086:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5087:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5088:     
1.235     brouard  5089:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5090:     
                   5091:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5092:     
                   5093:     printf("%d|",(int)age);fflush(stdout);
                   5094:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5095:     
                   5096:     /* Computing expectancies */
                   5097:     for(i=1; i<=nlstate;i++)
                   5098:       for(j=1; j<=nlstate;j++)
                   5099:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5100:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5101:          
                   5102:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5103: 
                   5104:        }
                   5105: 
                   5106:     fprintf(ficreseij,"%3.0f",age );
                   5107:     for(i=1; i<=nlstate;i++){
                   5108:       eip=0;
                   5109:       for(j=1; j<=nlstate;j++){
                   5110:        eip +=eij[i][j][(int)age];
                   5111:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5112:       }
                   5113:       fprintf(ficreseij,"%9.4f", eip );
                   5114:     }
                   5115:     fprintf(ficreseij,"\n");
                   5116:     
                   5117:   }
                   5118:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5119:   printf("\n");
                   5120:   fprintf(ficlog,"\n");
                   5121:   
                   5122: }
                   5123: 
1.235     brouard  5124:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5125: 
                   5126: {
                   5127:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5128:      to initial status i, ei. .
1.126     brouard  5129:   */
                   5130:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5131:   int nhstepma, nstepma; /* Decreasing with age */
                   5132:   double age, agelim, hf;
                   5133:   double ***p3matp, ***p3matm, ***varhe;
                   5134:   double **dnewm,**doldm;
                   5135:   double *xp, *xm;
                   5136:   double **gp, **gm;
                   5137:   double ***gradg, ***trgradg;
                   5138:   int theta;
                   5139: 
                   5140:   double eip, vip;
                   5141: 
                   5142:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5143:   xp=vector(1,npar);
                   5144:   xm=vector(1,npar);
                   5145:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5146:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5147:   
                   5148:   pstamp(ficresstdeij);
                   5149:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5150:   fprintf(ficresstdeij,"# Age");
                   5151:   for(i=1; i<=nlstate;i++){
                   5152:     for(j=1; j<=nlstate;j++)
                   5153:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5154:     fprintf(ficresstdeij," e%1d. ",i);
                   5155:   }
                   5156:   fprintf(ficresstdeij,"\n");
                   5157: 
                   5158:   pstamp(ficrescveij);
                   5159:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5160:   fprintf(ficrescveij,"# Age");
                   5161:   for(i=1; i<=nlstate;i++)
                   5162:     for(j=1; j<=nlstate;j++){
                   5163:       cptj= (j-1)*nlstate+i;
                   5164:       for(i2=1; i2<=nlstate;i2++)
                   5165:        for(j2=1; j2<=nlstate;j2++){
                   5166:          cptj2= (j2-1)*nlstate+i2;
                   5167:          if(cptj2 <= cptj)
                   5168:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5169:        }
                   5170:     }
                   5171:   fprintf(ficrescveij,"\n");
                   5172:   
                   5173:   if(estepm < stepm){
                   5174:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5175:   }
                   5176:   else  hstepm=estepm;   
                   5177:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5178:    * This is mainly to measure the difference between two models: for example
                   5179:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5180:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5181:    * progression in between and thus overestimating or underestimating according
                   5182:    * to the curvature of the survival function. If, for the same date, we 
                   5183:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5184:    * to compare the new estimate of Life expectancy with the same linear 
                   5185:    * hypothesis. A more precise result, taking into account a more precise
                   5186:    * curvature will be obtained if estepm is as small as stepm. */
                   5187: 
                   5188:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5189:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5190:      nhstepm is the number of hstepm from age to agelim 
                   5191:      nstepm is the number of stepm from age to agelin. 
                   5192:      Look at hpijx to understand the reason of that which relies in memory size
                   5193:      and note for a fixed period like estepm months */
                   5194:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5195:      survival function given by stepm (the optimization length). Unfortunately it
                   5196:      means that if the survival funtion is printed only each two years of age and if
                   5197:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5198:      results. So we changed our mind and took the option of the best precision.
                   5199:   */
                   5200:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5201: 
                   5202:   /* If stepm=6 months */
                   5203:   /* nhstepm age range expressed in number of stepm */
                   5204:   agelim=AGESUP;
                   5205:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5206:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5207:   /* if (stepm >= YEARM) hstepm=1;*/
                   5208:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5209:   
                   5210:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5211:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5212:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5213:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5214:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5215:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5216: 
                   5217:   for (age=bage; age<=fage; age ++){ 
                   5218:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5219:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5220:     /* if (stepm >= YEARM) hstepm=1;*/
                   5221:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5222:                
1.126     brouard  5223:     /* If stepm=6 months */
                   5224:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5225:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5226:     
                   5227:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5228:                
1.126     brouard  5229:     /* Computing  Variances of health expectancies */
                   5230:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5231:        decrease memory allocation */
                   5232:     for(theta=1; theta <=npar; theta++){
                   5233:       for(i=1; i<=npar; i++){ 
1.222     brouard  5234:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5235:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5236:       }
1.235     brouard  5237:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5238:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5239:                        
1.126     brouard  5240:       for(j=1; j<= nlstate; j++){
1.222     brouard  5241:        for(i=1; i<=nlstate; i++){
                   5242:          for(h=0; h<=nhstepm-1; h++){
                   5243:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5244:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5245:          }
                   5246:        }
1.126     brouard  5247:       }
1.218     brouard  5248:                        
1.126     brouard  5249:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5250:        for(h=0; h<=nhstepm-1; h++){
                   5251:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5252:        }
1.126     brouard  5253:     }/* End theta */
                   5254:     
                   5255:     
                   5256:     for(h=0; h<=nhstepm-1; h++)
                   5257:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5258:        for(theta=1; theta <=npar; theta++)
                   5259:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5260:     
1.218     brouard  5261:                
1.222     brouard  5262:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5263:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5264:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5265:                
1.222     brouard  5266:     printf("%d|",(int)age);fflush(stdout);
                   5267:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5268:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5269:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5270:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5271:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5272:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5273:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5274:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5275:       }
                   5276:     }
1.218     brouard  5277:                
1.126     brouard  5278:     /* Computing expectancies */
1.235     brouard  5279:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5280:     for(i=1; i<=nlstate;i++)
                   5281:       for(j=1; j<=nlstate;j++)
1.222     brouard  5282:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5283:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5284:                                        
1.222     brouard  5285:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5286:                                        
1.222     brouard  5287:        }
1.218     brouard  5288:                
1.126     brouard  5289:     fprintf(ficresstdeij,"%3.0f",age );
                   5290:     for(i=1; i<=nlstate;i++){
                   5291:       eip=0.;
                   5292:       vip=0.;
                   5293:       for(j=1; j<=nlstate;j++){
1.222     brouard  5294:        eip += eij[i][j][(int)age];
                   5295:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5296:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5297:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5298:       }
                   5299:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5300:     }
                   5301:     fprintf(ficresstdeij,"\n");
1.218     brouard  5302:                
1.126     brouard  5303:     fprintf(ficrescveij,"%3.0f",age );
                   5304:     for(i=1; i<=nlstate;i++)
                   5305:       for(j=1; j<=nlstate;j++){
1.222     brouard  5306:        cptj= (j-1)*nlstate+i;
                   5307:        for(i2=1; i2<=nlstate;i2++)
                   5308:          for(j2=1; j2<=nlstate;j2++){
                   5309:            cptj2= (j2-1)*nlstate+i2;
                   5310:            if(cptj2 <= cptj)
                   5311:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5312:          }
1.126     brouard  5313:       }
                   5314:     fprintf(ficrescveij,"\n");
1.218     brouard  5315:                
1.126     brouard  5316:   }
                   5317:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5318:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5319:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5320:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5321:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5322:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5323:   printf("\n");
                   5324:   fprintf(ficlog,"\n");
1.218     brouard  5325:        
1.126     brouard  5326:   free_vector(xm,1,npar);
                   5327:   free_vector(xp,1,npar);
                   5328:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5329:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5330:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5331: }
1.218     brouard  5332:  
1.126     brouard  5333: /************ Variance ******************/
1.235     brouard  5334:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5335:  {
                   5336:    /* Variance of health expectancies */
                   5337:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5338:    /* double **newm;*/
                   5339:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5340:   
                   5341:    /* int movingaverage(); */
                   5342:    double **dnewm,**doldm;
                   5343:    double **dnewmp,**doldmp;
                   5344:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5345:    int k;
                   5346:    double *xp;
                   5347:    double **gp, **gm;  /* for var eij */
                   5348:    double ***gradg, ***trgradg; /*for var eij */
                   5349:    double **gradgp, **trgradgp; /* for var p point j */
                   5350:    double *gpp, *gmp; /* for var p point j */
                   5351:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5352:    double ***p3mat;
                   5353:    double age,agelim, hf;
                   5354:    /* double ***mobaverage; */
                   5355:    int theta;
                   5356:    char digit[4];
                   5357:    char digitp[25];
                   5358: 
                   5359:    char fileresprobmorprev[FILENAMELENGTH];
                   5360: 
                   5361:    if(popbased==1){
                   5362:      if(mobilav!=0)
                   5363:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5364:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5365:    }
                   5366:    else 
                   5367:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5368: 
1.218     brouard  5369:    /* if (mobilav!=0) { */
                   5370:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5371:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5372:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5373:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5374:    /*   } */
                   5375:    /* } */
                   5376: 
                   5377:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5378:    sprintf(digit,"%-d",ij);
                   5379:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5380:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5381:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5382:    strcat(fileresprobmorprev,fileresu);
                   5383:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5384:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5385:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5386:    }
                   5387:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5388:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5389:    pstamp(ficresprobmorprev);
                   5390:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5391:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5392:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5393:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5394:    }
                   5395:    for(j=1;j<=cptcoveff;j++) 
                   5396:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5397:    fprintf(ficresprobmorprev,"\n");
                   5398: 
1.218     brouard  5399:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5400:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5401:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5402:      for(i=1; i<=nlstate;i++)
                   5403:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5404:    }  
                   5405:    fprintf(ficresprobmorprev,"\n");
                   5406:   
                   5407:    fprintf(ficgp,"\n# Routine varevsij");
                   5408:    fprintf(ficgp,"\nunset title \n");
                   5409:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5410:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5411:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5412:    /*   } */
                   5413:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5414:    pstamp(ficresvij);
                   5415:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5416:    if(popbased==1)
                   5417:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5418:    else
                   5419:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5420:    fprintf(ficresvij,"# Age");
                   5421:    for(i=1; i<=nlstate;i++)
                   5422:      for(j=1; j<=nlstate;j++)
                   5423:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5424:    fprintf(ficresvij,"\n");
                   5425: 
                   5426:    xp=vector(1,npar);
                   5427:    dnewm=matrix(1,nlstate,1,npar);
                   5428:    doldm=matrix(1,nlstate,1,nlstate);
                   5429:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5430:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5431: 
                   5432:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5433:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5434:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5435:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5436:   
1.218     brouard  5437:    if(estepm < stepm){
                   5438:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5439:    }
                   5440:    else  hstepm=estepm;   
                   5441:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5442:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5443:       nhstepm is the number of hstepm from age to agelim 
                   5444:       nstepm is the number of stepm from age to agelim. 
                   5445:       Look at function hpijx to understand why because of memory size limitations, 
                   5446:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5447:       survival function given by stepm (the optimization length). Unfortunately it
                   5448:       means that if the survival funtion is printed every two years of age and if
                   5449:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5450:       results. So we changed our mind and took the option of the best precision.
                   5451:    */
                   5452:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5453:    agelim = AGESUP;
                   5454:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5455:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5456:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5457:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5458:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5459:      gp=matrix(0,nhstepm,1,nlstate);
                   5460:      gm=matrix(0,nhstepm,1,nlstate);
                   5461:                
                   5462:                
                   5463:      for(theta=1; theta <=npar; theta++){
                   5464:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5465:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5466:        }
                   5467:                        
1.242     brouard  5468:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5469:                        
                   5470:        if (popbased==1) {
                   5471:         if(mobilav ==0){
                   5472:           for(i=1; i<=nlstate;i++)
                   5473:             prlim[i][i]=probs[(int)age][i][ij];
                   5474:         }else{ /* mobilav */ 
                   5475:           for(i=1; i<=nlstate;i++)
                   5476:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5477:         }
                   5478:        }
                   5479:                        
1.235     brouard  5480:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5481:        for(j=1; j<= nlstate; j++){
                   5482:         for(h=0; h<=nhstepm; h++){
                   5483:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5484:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5485:         }
                   5486:        }
                   5487:        /* Next for computing probability of death (h=1 means
                   5488:          computed over hstepm matrices product = hstepm*stepm months) 
                   5489:          as a weighted average of prlim.
                   5490:        */
                   5491:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5492:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5493:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5494:        }    
                   5495:        /* end probability of death */
                   5496:                        
                   5497:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5498:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5499:                        
1.242     brouard  5500:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5501:                        
                   5502:        if (popbased==1) {
                   5503:         if(mobilav ==0){
                   5504:           for(i=1; i<=nlstate;i++)
                   5505:             prlim[i][i]=probs[(int)age][i][ij];
                   5506:         }else{ /* mobilav */ 
                   5507:           for(i=1; i<=nlstate;i++)
                   5508:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5509:         }
                   5510:        }
                   5511:                        
1.235     brouard  5512:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5513:                        
                   5514:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5515:         for(h=0; h<=nhstepm; h++){
                   5516:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5517:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5518:         }
                   5519:        }
                   5520:        /* This for computing probability of death (h=1 means
                   5521:          computed over hstepm matrices product = hstepm*stepm months) 
                   5522:          as a weighted average of prlim.
                   5523:        */
                   5524:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5525:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5526:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5527:        }    
                   5528:        /* end probability of death */
                   5529:                        
                   5530:        for(j=1; j<= nlstate; j++) /* vareij */
                   5531:         for(h=0; h<=nhstepm; h++){
                   5532:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5533:         }
                   5534:                        
                   5535:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5536:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5537:        }
                   5538:                        
                   5539:      } /* End theta */
                   5540:                
                   5541:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5542:                
                   5543:      for(h=0; h<=nhstepm; h++) /* veij */
                   5544:        for(j=1; j<=nlstate;j++)
                   5545:         for(theta=1; theta <=npar; theta++)
                   5546:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5547:                
                   5548:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5549:        for(theta=1; theta <=npar; theta++)
                   5550:         trgradgp[j][theta]=gradgp[theta][j];
                   5551:                
                   5552:                
                   5553:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5554:      for(i=1;i<=nlstate;i++)
                   5555:        for(j=1;j<=nlstate;j++)
                   5556:         vareij[i][j][(int)age] =0.;
                   5557:                
                   5558:      for(h=0;h<=nhstepm;h++){
                   5559:        for(k=0;k<=nhstepm;k++){
                   5560:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5561:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5562:         for(i=1;i<=nlstate;i++)
                   5563:           for(j=1;j<=nlstate;j++)
                   5564:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5565:        }
                   5566:      }
                   5567:                
                   5568:      /* pptj */
                   5569:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5570:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5571:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5572:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5573:         varppt[j][i]=doldmp[j][i];
                   5574:      /* end ppptj */
                   5575:      /*  x centered again */
                   5576:                
1.242     brouard  5577:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5578:                
                   5579:      if (popbased==1) {
                   5580:        if(mobilav ==0){
                   5581:         for(i=1; i<=nlstate;i++)
                   5582:           prlim[i][i]=probs[(int)age][i][ij];
                   5583:        }else{ /* mobilav */ 
                   5584:         for(i=1; i<=nlstate;i++)
                   5585:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   5586:        }
                   5587:      }
                   5588:                
                   5589:      /* This for computing probability of death (h=1 means
                   5590:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   5591:        as a weighted average of prlim.
                   5592:      */
1.235     brouard  5593:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  5594:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5595:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   5596:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   5597:      }    
                   5598:      /* end probability of death */
                   5599:                
                   5600:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   5601:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5602:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   5603:        for(i=1; i<=nlstate;i++){
                   5604:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   5605:        }
                   5606:      } 
                   5607:      fprintf(ficresprobmorprev,"\n");
                   5608:                
                   5609:      fprintf(ficresvij,"%.0f ",age );
                   5610:      for(i=1; i<=nlstate;i++)
                   5611:        for(j=1; j<=nlstate;j++){
                   5612:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   5613:        }
                   5614:      fprintf(ficresvij,"\n");
                   5615:      free_matrix(gp,0,nhstepm,1,nlstate);
                   5616:      free_matrix(gm,0,nhstepm,1,nlstate);
                   5617:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   5618:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   5619:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5620:    } /* End age */
                   5621:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   5622:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   5623:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   5624:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   5625:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   5626:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   5627:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   5628:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   5629:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5630:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   5631:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5632:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5633:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   5634:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   5635:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   5636:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   5637:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5638:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  5639:     */
1.218     brouard  5640:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   5641:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  5642: 
1.218     brouard  5643:    free_vector(xp,1,npar);
                   5644:    free_matrix(doldm,1,nlstate,1,nlstate);
                   5645:    free_matrix(dnewm,1,nlstate,1,npar);
                   5646:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5647:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   5648:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5649:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5650:    fclose(ficresprobmorprev);
                   5651:    fflush(ficgp);
                   5652:    fflush(fichtm); 
                   5653:  }  /* end varevsij */
1.126     brouard  5654: 
                   5655: /************ Variance of prevlim ******************/
1.235     brouard  5656:  void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  5657: {
1.205     brouard  5658:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  5659:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  5660: 
1.126     brouard  5661:   double **dnewm,**doldm;
                   5662:   int i, j, nhstepm, hstepm;
                   5663:   double *xp;
                   5664:   double *gp, *gm;
                   5665:   double **gradg, **trgradg;
1.208     brouard  5666:   double **mgm, **mgp;
1.126     brouard  5667:   double age,agelim;
                   5668:   int theta;
                   5669:   
                   5670:   pstamp(ficresvpl);
                   5671:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  5672:   fprintf(ficresvpl,"# Age ");
                   5673:   if(nresult >=1)
                   5674:     fprintf(ficresvpl," Result# ");
1.126     brouard  5675:   for(i=1; i<=nlstate;i++)
                   5676:       fprintf(ficresvpl," %1d-%1d",i,i);
                   5677:   fprintf(ficresvpl,"\n");
                   5678: 
                   5679:   xp=vector(1,npar);
                   5680:   dnewm=matrix(1,nlstate,1,npar);
                   5681:   doldm=matrix(1,nlstate,1,nlstate);
                   5682:   
                   5683:   hstepm=1*YEARM; /* Every year of age */
                   5684:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   5685:   agelim = AGESUP;
                   5686:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5687:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5688:     if (stepm >= YEARM) hstepm=1;
                   5689:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   5690:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  5691:     mgp=matrix(1,npar,1,nlstate);
                   5692:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  5693:     gp=vector(1,nlstate);
                   5694:     gm=vector(1,nlstate);
                   5695: 
                   5696:     for(theta=1; theta <=npar; theta++){
                   5697:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   5698:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5699:       }
1.209     brouard  5700:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5701:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5702:       else
1.235     brouard  5703:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5704:       for(i=1;i<=nlstate;i++){
1.126     brouard  5705:        gp[i] = prlim[i][i];
1.208     brouard  5706:        mgp[theta][i] = prlim[i][i];
                   5707:       }
1.126     brouard  5708:       for(i=1; i<=npar; i++) /* Computes gradient */
                   5709:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  5710:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5711:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5712:       else
1.235     brouard  5713:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5714:       for(i=1;i<=nlstate;i++){
1.126     brouard  5715:        gm[i] = prlim[i][i];
1.208     brouard  5716:        mgm[theta][i] = prlim[i][i];
                   5717:       }
1.126     brouard  5718:       for(i=1;i<=nlstate;i++)
                   5719:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  5720:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  5721:     } /* End theta */
                   5722: 
                   5723:     trgradg =matrix(1,nlstate,1,npar);
                   5724: 
                   5725:     for(j=1; j<=nlstate;j++)
                   5726:       for(theta=1; theta <=npar; theta++)
                   5727:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  5728:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5729:     /*   printf("\nmgm mgp %d ",(int)age); */
                   5730:     /*   for(j=1; j<=nlstate;j++){ */
                   5731:     /*         printf(" %d ",j); */
                   5732:     /*         for(theta=1; theta <=npar; theta++) */
                   5733:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   5734:     /*         printf("\n "); */
                   5735:     /*   } */
                   5736:     /* } */
                   5737:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5738:     /*   printf("\n gradg %d ",(int)age); */
                   5739:     /*   for(j=1; j<=nlstate;j++){ */
                   5740:     /*         printf("%d ",j); */
                   5741:     /*         for(theta=1; theta <=npar; theta++) */
                   5742:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   5743:     /*         printf("\n "); */
                   5744:     /*   } */
                   5745:     /* } */
1.126     brouard  5746: 
                   5747:     for(i=1;i<=nlstate;i++)
                   5748:       varpl[i][(int)age] =0.;
1.209     brouard  5749:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.205     brouard  5750:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   5751:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
                   5752:     }else{
1.126     brouard  5753:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   5754:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  5755:     }
1.126     brouard  5756:     for(i=1;i<=nlstate;i++)
                   5757:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   5758: 
                   5759:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  5760:     if(nresult >=1)
                   5761:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  5762:     for(i=1; i<=nlstate;i++)
                   5763:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   5764:     fprintf(ficresvpl,"\n");
                   5765:     free_vector(gp,1,nlstate);
                   5766:     free_vector(gm,1,nlstate);
1.208     brouard  5767:     free_matrix(mgm,1,npar,1,nlstate);
                   5768:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  5769:     free_matrix(gradg,1,npar,1,nlstate);
                   5770:     free_matrix(trgradg,1,nlstate,1,npar);
                   5771:   } /* End age */
                   5772: 
                   5773:   free_vector(xp,1,npar);
                   5774:   free_matrix(doldm,1,nlstate,1,npar);
                   5775:   free_matrix(dnewm,1,nlstate,1,nlstate);
                   5776: 
                   5777: }
                   5778: 
                   5779: /************ Variance of one-step probabilities  ******************/
                   5780: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  5781:  {
                   5782:    int i, j=0,  k1, l1, tj;
                   5783:    int k2, l2, j1,  z1;
                   5784:    int k=0, l;
                   5785:    int first=1, first1, first2;
                   5786:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   5787:    double **dnewm,**doldm;
                   5788:    double *xp;
                   5789:    double *gp, *gm;
                   5790:    double **gradg, **trgradg;
                   5791:    double **mu;
                   5792:    double age, cov[NCOVMAX+1];
                   5793:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   5794:    int theta;
                   5795:    char fileresprob[FILENAMELENGTH];
                   5796:    char fileresprobcov[FILENAMELENGTH];
                   5797:    char fileresprobcor[FILENAMELENGTH];
                   5798:    double ***varpij;
                   5799: 
                   5800:    strcpy(fileresprob,"PROB_"); 
                   5801:    strcat(fileresprob,fileres);
                   5802:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   5803:      printf("Problem with resultfile: %s\n", fileresprob);
                   5804:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   5805:    }
                   5806:    strcpy(fileresprobcov,"PROBCOV_"); 
                   5807:    strcat(fileresprobcov,fileresu);
                   5808:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   5809:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   5810:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   5811:    }
                   5812:    strcpy(fileresprobcor,"PROBCOR_"); 
                   5813:    strcat(fileresprobcor,fileresu);
                   5814:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   5815:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   5816:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   5817:    }
                   5818:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   5819:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   5820:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   5821:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   5822:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   5823:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   5824:    pstamp(ficresprob);
                   5825:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   5826:    fprintf(ficresprob,"# Age");
                   5827:    pstamp(ficresprobcov);
                   5828:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   5829:    fprintf(ficresprobcov,"# Age");
                   5830:    pstamp(ficresprobcor);
                   5831:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   5832:    fprintf(ficresprobcor,"# Age");
1.126     brouard  5833: 
                   5834: 
1.222     brouard  5835:    for(i=1; i<=nlstate;i++)
                   5836:      for(j=1; j<=(nlstate+ndeath);j++){
                   5837:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   5838:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   5839:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   5840:      }  
                   5841:    /* fprintf(ficresprob,"\n");
                   5842:       fprintf(ficresprobcov,"\n");
                   5843:       fprintf(ficresprobcor,"\n");
                   5844:    */
                   5845:    xp=vector(1,npar);
                   5846:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   5847:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   5848:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   5849:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   5850:    first=1;
                   5851:    fprintf(ficgp,"\n# Routine varprob");
                   5852:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   5853:    fprintf(fichtm,"\n");
                   5854: 
                   5855:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.</li>\n",optionfilehtmcov);
                   5856:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   5857:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  5858: and drawn. It helps understanding how is the covariance between two incidences.\
                   5859:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  5860:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  5861: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   5862: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   5863: standard deviations wide on each axis. <br>\
                   5864:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   5865:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   5866: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   5867: 
1.222     brouard  5868:    cov[1]=1;
                   5869:    /* tj=cptcoveff; */
1.225     brouard  5870:    tj = (int) pow(2,cptcoveff);
1.222     brouard  5871:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   5872:    j1=0;
1.224     brouard  5873:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  5874:      if  (cptcovn>0) {
                   5875:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  5876:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5877:        fprintf(ficresprob, "**********\n#\n");
                   5878:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  5879:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5880:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  5881:                        
1.222     brouard  5882:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  5883:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5884:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  5885:                        
                   5886:                        
1.222     brouard  5887:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  5888:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5889:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  5890:                        
1.222     brouard  5891:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  5892:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5893:        fprintf(ficresprobcor, "**********\n#");    
                   5894:        if(invalidvarcomb[j1]){
                   5895:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   5896:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   5897:         continue;
                   5898:        }
                   5899:      }
                   5900:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   5901:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   5902:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   5903:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   5904:      for (age=bage; age<=fage; age ++){ 
                   5905:        cov[2]=age;
                   5906:        if(nagesqr==1)
                   5907:         cov[3]= age*age;
                   5908:        for (k=1; k<=cptcovn;k++) {
                   5909:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   5910:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   5911:                                                                    * 1  1 1 1 1
                   5912:                                                                    * 2  2 1 1 1
                   5913:                                                                    * 3  1 2 1 1
                   5914:                                                                    */
                   5915:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   5916:        }
                   5917:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   5918:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   5919:        for (k=1; k<=cptcovprod;k++)
                   5920:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  5921:                        
                   5922:                        
1.222     brouard  5923:        for(theta=1; theta <=npar; theta++){
                   5924:         for(i=1; i<=npar; i++)
                   5925:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  5926:                                
1.222     brouard  5927:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  5928:                                
1.222     brouard  5929:         k=0;
                   5930:         for(i=1; i<= (nlstate); i++){
                   5931:           for(j=1; j<=(nlstate+ndeath);j++){
                   5932:             k=k+1;
                   5933:             gp[k]=pmmij[i][j];
                   5934:           }
                   5935:         }
1.220     brouard  5936:                                
1.222     brouard  5937:         for(i=1; i<=npar; i++)
                   5938:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  5939:                                
1.222     brouard  5940:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   5941:         k=0;
                   5942:         for(i=1; i<=(nlstate); i++){
                   5943:           for(j=1; j<=(nlstate+ndeath);j++){
                   5944:             k=k+1;
                   5945:             gm[k]=pmmij[i][j];
                   5946:           }
                   5947:         }
1.220     brouard  5948:                                
1.222     brouard  5949:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   5950:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   5951:        }
1.126     brouard  5952: 
1.222     brouard  5953:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   5954:         for(theta=1; theta <=npar; theta++)
                   5955:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  5956:                        
1.222     brouard  5957:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   5958:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  5959:                        
1.222     brouard  5960:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  5961:                        
1.222     brouard  5962:        k=0;
                   5963:        for(i=1; i<=(nlstate); i++){
                   5964:         for(j=1; j<=(nlstate+ndeath);j++){
                   5965:           k=k+1;
                   5966:           mu[k][(int) age]=pmmij[i][j];
                   5967:         }
                   5968:        }
                   5969:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   5970:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   5971:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  5972:                        
1.222     brouard  5973:        /*printf("\n%d ",(int)age);
                   5974:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   5975:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   5976:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   5977:         }*/
1.220     brouard  5978:                        
1.222     brouard  5979:        fprintf(ficresprob,"\n%d ",(int)age);
                   5980:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   5981:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  5982:                        
1.222     brouard  5983:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   5984:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   5985:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   5986:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   5987:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   5988:        }
                   5989:        i=0;
                   5990:        for (k=1; k<=(nlstate);k++){
                   5991:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   5992:           i++;
                   5993:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   5994:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   5995:           for (j=1; j<=i;j++){
                   5996:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   5997:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   5998:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   5999:           }
                   6000:         }
                   6001:        }/* end of loop for state */
                   6002:      } /* end of loop for age */
                   6003:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6004:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6005:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6006:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6007:     
                   6008:      /* Confidence intervalle of pij  */
                   6009:      /*
                   6010:        fprintf(ficgp,"\nunset parametric;unset label");
                   6011:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6012:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6013:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6014:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6015:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6016:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6017:      */
                   6018:                
                   6019:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6020:      first1=1;first2=2;
                   6021:      for (k2=1; k2<=(nlstate);k2++){
                   6022:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6023:         if(l2==k2) continue;
                   6024:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6025:         for (k1=1; k1<=(nlstate);k1++){
                   6026:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6027:             if(l1==k1) continue;
                   6028:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6029:             if(i<=j) continue;
                   6030:             for (age=bage; age<=fage; age ++){ 
                   6031:               if ((int)age %5==0){
                   6032:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6033:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6034:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6035:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6036:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6037:                 c12=cv12/sqrt(v1*v2);
                   6038:                 /* Computing eigen value of matrix of covariance */
                   6039:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6040:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6041:                 if ((lc2 <0) || (lc1 <0) ){
                   6042:                   if(first2==1){
                   6043:                     first1=0;
                   6044:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6045:                   }
                   6046:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6047:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6048:                   /* lc2=fabs(lc2); */
                   6049:                 }
1.220     brouard  6050:                                                                
1.222     brouard  6051:                 /* Eigen vectors */
                   6052:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   6053:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6054:                 v21=(lc1-v1)/cv12*v11;
                   6055:                 v12=-v21;
                   6056:                 v22=v11;
                   6057:                 tnalp=v21/v11;
                   6058:                 if(first1==1){
                   6059:                   first1=0;
                   6060:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6061:                 }
                   6062:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6063:                 /*printf(fignu*/
                   6064:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6065:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6066:                 if(first==1){
                   6067:                   first=0;
                   6068:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6069:                   fprintf(ficgp,"\nset parametric;unset label");
                   6070:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6071:                   fprintf(ficgp,"\nset ter svg size 640, 480");
                   6072:                   fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6073:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6074: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6075:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6076:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6077:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6078:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6079:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6080:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6081:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6082:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
                   6083:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                                                         \
                   6084:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6085:                 }else{
                   6086:                   first=0;
                   6087:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6088:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6089:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6090:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
                   6091:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                 \
                   6092:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6093:                 }/* if first */
                   6094:               } /* age mod 5 */
                   6095:             } /* end loop age */
                   6096:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6097:             first=1;
                   6098:           } /*l12 */
                   6099:         } /* k12 */
                   6100:        } /*l1 */
                   6101:      }/* k1 */
                   6102:    }  /* loop on combination of covariates j1 */
                   6103:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6104:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6105:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6106:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6107:    free_vector(xp,1,npar);
                   6108:    fclose(ficresprob);
                   6109:    fclose(ficresprobcov);
                   6110:    fclose(ficresprobcor);
                   6111:    fflush(ficgp);
                   6112:    fflush(fichtmcov);
                   6113:  }
1.126     brouard  6114: 
                   6115: 
                   6116: /******************* Printing html file ***********/
1.201     brouard  6117: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6118:                  int lastpass, int stepm, int weightopt, char model[],\
                   6119:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.217     brouard  6120:                  int popforecast, int prevfcast, int backcast, int estepm , \
1.213     brouard  6121:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   6122:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.237     brouard  6123:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6124: 
                   6125:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6126:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6127: </ul>");
1.237     brouard  6128:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6129: </ul>", model);
1.214     brouard  6130:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6131:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6132:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6133:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6134:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6135:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6136:    fprintf(fichtm,"\
                   6137:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6138:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6139:    fprintf(fichtm,"\
1.217     brouard  6140:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6141:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6142:    fprintf(fichtm,"\
1.126     brouard  6143:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6144:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6145:    fprintf(fichtm,"\
1.217     brouard  6146:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6147:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6148:    fprintf(fichtm,"\
1.211     brouard  6149:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6150:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6151:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6152:    if(prevfcast==1){
                   6153:      fprintf(fichtm,"\
                   6154:  - Prevalence projections by age and states:                           \
1.201     brouard  6155:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6156:    }
1.126     brouard  6157: 
1.222     brouard  6158:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
1.126     brouard  6159: 
1.225     brouard  6160:    m=pow(2,cptcoveff);
1.222     brouard  6161:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6162: 
1.222     brouard  6163:    jj1=0;
1.237     brouard  6164: 
                   6165:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6166:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.237     brouard  6167:      if(TKresult[nres]!= k1)
                   6168:        continue;
1.220     brouard  6169: 
1.222     brouard  6170:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6171:      jj1++;
                   6172:      if (cptcovn > 0) {
                   6173:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6174:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6175:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6176:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6177:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6178:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6179:        }
1.237     brouard  6180:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6181:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6182:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6183:       }
                   6184:        
1.230     brouard  6185:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6186:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6187:        if(invalidvarcomb[k1]){
                   6188:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6189:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6190:         continue;
                   6191:        }
                   6192:      }
                   6193:      /* aij, bij */
1.241     brouard  6194:      fprintf(fichtm,"<br>- Logit model (yours is: 1+age+%s), for example: logit(pij)=log(pij/pii)= aij+ bij age + V1 age + etc. as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
                   6195: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6196:      /* Pij */
1.241     brouard  6197:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6198: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6199:      /* Quasi-incidences */
                   6200:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6201:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6202:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6203: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6204: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6205:      /* Survival functions (period) in state j */
                   6206:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6207:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6208: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6209:      }
                   6210:      /* State specific survival functions (period) */
                   6211:      for(cpt=1; cpt<=nlstate;cpt++){
                   6212:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6213:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.241     brouard  6214:  <a href=\"%s_%d-%d-%d.svg\">%s_%d%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6215:      }
                   6216:      /* Period (stable) prevalence in each health state */
                   6217:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6218:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6219: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6220:      }
                   6221:      if(backcast==1){
                   6222:        /* Period (stable) back prevalence in each health state */
                   6223:        for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6224:         fprintf(fichtm,"<br>\n- Convergence to period (stable) back prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6225: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6226:        }
1.217     brouard  6227:      }
1.222     brouard  6228:      if(prevfcast==1){
                   6229:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6230:        for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6231:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f) up to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6232: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6233:        }
                   6234:      }
1.220     brouard  6235:         
1.222     brouard  6236:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6237:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6238: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6239:      }
                   6240:      /* } /\* end i1 *\/ */
                   6241:    }/* End k1 */
                   6242:    fprintf(fichtm,"</ul>");
1.126     brouard  6243: 
1.222     brouard  6244:    fprintf(fichtm,"\
1.126     brouard  6245: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6246:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6247:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6248: But because parameters are usually highly correlated (a higher incidence of disability \
                   6249: and a higher incidence of recovery can give very close observed transition) it might \
                   6250: be very useful to look not only at linear confidence intervals estimated from the \
                   6251: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6252: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6253: covariance matrix of the one-step probabilities. \
                   6254: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6255: 
1.222     brouard  6256:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6257:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6258:    fprintf(fichtm,"\
1.126     brouard  6259:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6260:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6261: 
1.222     brouard  6262:    fprintf(fichtm,"\
1.126     brouard  6263:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6264:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6265:    fprintf(fichtm,"\
1.126     brouard  6266:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6267:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6268:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6269:    fprintf(fichtm,"\
1.126     brouard  6270:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6271:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6272:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6273:    fprintf(fichtm,"\
1.128     brouard  6274:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6275:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6276:    fprintf(fichtm,"\
1.128     brouard  6277:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6278:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6279:    fprintf(fichtm,"\
1.126     brouard  6280:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6281:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6282: 
                   6283: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6284: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6285: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6286: /*     <br>",fileres,fileres,fileres,fileres); */
                   6287: /*  else  */
                   6288: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6289:    fflush(fichtm);
                   6290:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6291: 
1.225     brouard  6292:    m=pow(2,cptcoveff);
1.222     brouard  6293:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6294: 
1.222     brouard  6295:    jj1=0;
1.237     brouard  6296: 
1.241     brouard  6297:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6298:    for(k1=1; k1<=m;k1++){
1.237     brouard  6299:      if(TKresult[nres]!= k1)
                   6300:        continue;
1.222     brouard  6301:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6302:      jj1++;
1.126     brouard  6303:      if (cptcovn > 0) {
                   6304:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6305:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6306:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6307:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6308:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6309:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6310:       }
                   6311: 
1.126     brouard  6312:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6313: 
1.222     brouard  6314:        if(invalidvarcomb[k1]){
                   6315:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6316:         continue;
                   6317:        }
1.126     brouard  6318:      }
                   6319:      for(cpt=1; cpt<=nlstate;cpt++) {
1.218     brouard  6320:        fprintf(fichtm,"\n<br>- Observed (cross-sectional) and period (incidence based) \
1.241     brouard  6321: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
                   6322: <img src=\"%s_%d-%d-%d.svg\">",cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  6323:      }
                   6324:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6325: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6326: true period expectancies (those weighted with period prevalences are also\
                   6327:  drawn in addition to the population based expectancies computed using\
1.241     brouard  6328:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   6329: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  6330:      /* } /\* end i1 *\/ */
                   6331:    }/* End k1 */
1.241     brouard  6332:   }/* End nres */
1.222     brouard  6333:    fprintf(fichtm,"</ul>");
                   6334:    fflush(fichtm);
1.126     brouard  6335: }
                   6336: 
                   6337: /******************* Gnuplot file **************/
1.223     brouard  6338: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[]){
1.126     brouard  6339: 
                   6340:   char dirfileres[132],optfileres[132];
1.223     brouard  6341:   char gplotcondition[132];
1.237     brouard  6342:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6343:   int lv=0, vlv=0, kl=0;
1.130     brouard  6344:   int ng=0;
1.201     brouard  6345:   int vpopbased;
1.223     brouard  6346:   int ioffset; /* variable offset for columns */
1.235     brouard  6347:   int nres=0; /* Index of resultline */
1.219     brouard  6348: 
1.126     brouard  6349: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6350: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6351: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6352: /*   } */
                   6353: 
                   6354:   /*#ifdef windows */
                   6355:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6356:   /*#endif */
1.225     brouard  6357:   m=pow(2,cptcoveff);
1.126     brouard  6358: 
1.202     brouard  6359:   /* Contribution to likelihood */
                   6360:   /* Plot the probability implied in the likelihood */
1.223     brouard  6361:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6362:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6363:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6364:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6365: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6366:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6367: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6368:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6369:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6370:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6371:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6372:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6373:   for (i=1; i<= nlstate ; i ++) {
                   6374:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6375:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6376:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6377:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6378:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6379:     }
                   6380:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6381:   }
                   6382:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6383:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6384:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6385:   fprintf(ficgp,"\nset out;unset log\n");
                   6386:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6387: 
1.126     brouard  6388:   strcpy(dirfileres,optionfilefiname);
                   6389:   strcpy(optfileres,"vpl");
1.223     brouard  6390:   /* 1eme*/
1.238     brouard  6391:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   6392:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  6393:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  6394:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
                   6395:        if(TKresult[nres]!= k1)
                   6396:          continue;
                   6397:        /* We are interested in selected combination by the resultline */
                   6398:        printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt);
                   6399:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
                   6400:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6401:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   6402:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6403:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6404:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6405:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   6406:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
                   6407:          printf(" V%d=%d ",Tvaraff[k],vlv);
                   6408:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6409:        }
                   6410:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6411:          printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6412:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6413:        }       
                   6414:        printf("\n#\n");
                   6415:        fprintf(ficgp,"\n#\n");
                   6416:        if(invalidvarcomb[k1]){
                   6417:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6418:          continue;
                   6419:        }
1.235     brouard  6420:       
1.241     brouard  6421:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   6422:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
                   6423:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres);
1.235     brouard  6424:       
1.238     brouard  6425:        for (i=1; i<= nlstate ; i ++) {
                   6426:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6427:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   6428:        }
1.242     brouard  6429:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres);
1.238     brouard  6430:        for (i=1; i<= nlstate ; i ++) {
                   6431:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6432:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6433:        } 
1.242     brouard  6434:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); 
1.238     brouard  6435:        for (i=1; i<= nlstate ; i ++) {
                   6436:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6437:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6438:        }  
                   6439:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1));
                   6440:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   6441:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  6442:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  6443:          if(cptcoveff ==0){
                   6444:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line ",        2+(cpt-1),  cpt );
                   6445:          }else{
                   6446:            kl=0;
                   6447:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   6448:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6449:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6450:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6451:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6452:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  6453:              kl++;
1.238     brouard  6454:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6455:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6456:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6457:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6458:              if(k==cptcoveff){
                   6459:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  6460:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  6461:              }else{
                   6462:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   6463:                kl++;
                   6464:              }
                   6465:            } /* end covariate */
                   6466:          } /* end if no covariate */
                   6467:        } /* end if backcast */
                   6468:        fprintf(ficgp,"\nset out \n");
                   6469:       } /* nres */
1.201     brouard  6470:     } /* k1 */
                   6471:   } /* cpt */
1.235     brouard  6472: 
                   6473:   
1.126     brouard  6474:   /*2 eme*/
1.238     brouard  6475:   for (k1=1; k1<= m ; k1 ++){  
                   6476:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6477:       if(TKresult[nres]!= k1)
                   6478:        continue;
                   6479:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
                   6480:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  6481:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6482:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6483:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6484:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6485:        vlv= nbcode[Tvaraff[k]][lv];
                   6486:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6487:       }
1.237     brouard  6488:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  6489:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  6490:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  6491:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  6492:       }
1.211     brouard  6493:       fprintf(ficgp,"\n#\n");
1.223     brouard  6494:       if(invalidvarcomb[k1]){
                   6495:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6496:        continue;
                   6497:       }
1.219     brouard  6498:                        
1.241     brouard  6499:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  6500:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
                   6501:        if(vpopbased==0)
                   6502:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
                   6503:        else
                   6504:          fprintf(ficgp,"\nreplot ");
                   6505:        for (i=1; i<= nlstate+1 ; i ++) {
                   6506:          k=2*i;
                   6507:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1, vpopbased);
                   6508:          for (j=1; j<= nlstate+1 ; j ++) {
                   6509:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6510:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6511:          }   
                   6512:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   6513:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
                   6514:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6515:          for (j=1; j<= nlstate+1 ; j ++) {
                   6516:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6517:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6518:          }   
                   6519:          fprintf(ficgp,"\" t\"\" w l lt 0,");
                   6520:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6521:          for (j=1; j<= nlstate+1 ; j ++) {
                   6522:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6523:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6524:          }   
                   6525:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   6526:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   6527:        } /* state */
                   6528:       } /* vpopbased */
1.244   ! brouard  6529:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  6530:     } /* end nres */
                   6531:   } /* k1 end 2 eme*/
                   6532:        
                   6533:        
                   6534:   /*3eme*/
                   6535:   for (k1=1; k1<= m ; k1 ++){
                   6536:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.240     brouard  6537:       if(TKresult[nres]!= k1)
1.238     brouard  6538:        continue;
                   6539: 
                   6540:       for (cpt=1; cpt<= nlstate ; cpt ++) {
                   6541:        fprintf(ficgp,"\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
                   6542:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6543:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6544:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6545:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6546:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6547:          vlv= nbcode[Tvaraff[k]][lv];
                   6548:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6549:        }
                   6550:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6551:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6552:        }       
                   6553:        fprintf(ficgp,"\n#\n");
                   6554:        if(invalidvarcomb[k1]){
                   6555:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6556:          continue;
                   6557:        }
                   6558:                        
                   6559:        /*       k=2+nlstate*(2*cpt-2); */
                   6560:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  6561:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.238     brouard  6562:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.201     brouard  6563: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),k1-1,k1-1,k,cpt);
1.238     brouard  6564:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6565:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6566:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   6567:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6568:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6569:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  6570:                                
1.238     brouard  6571:        */
                   6572:        for (i=1; i< nlstate ; i ++) {
                   6573:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+i,cpt,i+1);
                   6574:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  6575:                                
1.238     brouard  6576:        } 
                   6577:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+nlstate,cpt);
                   6578:       }
                   6579:     } /* end nres */
                   6580:   } /* end kl 3eme */
1.126     brouard  6581:   
1.223     brouard  6582:   /* 4eme */
1.201     brouard  6583:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  6584:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   6585:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6586:       if(TKresult[nres]!= k1)
1.223     brouard  6587:        continue;
1.238     brouard  6588:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
                   6589:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   6590:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6591:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6592:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6593:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6594:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6595:          vlv= nbcode[Tvaraff[k]][lv];
                   6596:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6597:        }
                   6598:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6599:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6600:        }       
                   6601:        fprintf(ficgp,"\n#\n");
                   6602:        if(invalidvarcomb[k1]){
                   6603:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6604:          continue;
1.223     brouard  6605:        }
1.238     brouard  6606:       
1.241     brouard  6607:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.238     brouard  6608:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6609: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6610:        k=3;
                   6611:        for (i=1; i<= nlstate ; i ++){
                   6612:          if(i==1){
                   6613:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6614:          }else{
                   6615:            fprintf(ficgp,", '' ");
                   6616:          }
                   6617:          l=(nlstate+ndeath)*(i-1)+1;
                   6618:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6619:          for (j=2; j<= nlstate+ndeath ; j ++)
                   6620:            fprintf(ficgp,"+$%d",k+l+j-1);
                   6621:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   6622:        } /* nlstate */
                   6623:        fprintf(ficgp,"\nset out\n");
                   6624:       } /* end cpt state*/ 
                   6625:     } /* end nres */
                   6626:   } /* end covariate k1 */  
                   6627: 
1.220     brouard  6628: /* 5eme */
1.201     brouard  6629:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  6630:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   6631:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6632:       if(TKresult[nres]!= k1)
1.227     brouard  6633:        continue;
1.238     brouard  6634:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
                   6635:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   6636:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6637:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6638:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6639:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6640:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6641:          vlv= nbcode[Tvaraff[k]][lv];
                   6642:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6643:        }
                   6644:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6645:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6646:        }       
                   6647:        fprintf(ficgp,"\n#\n");
                   6648:        if(invalidvarcomb[k1]){
                   6649:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6650:          continue;
                   6651:        }
1.227     brouard  6652:       
1.241     brouard  6653:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.238     brouard  6654:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6655: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6656:        k=3;
                   6657:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6658:          if(j==1)
                   6659:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6660:          else
                   6661:            fprintf(ficgp,", '' ");
                   6662:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6663:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   6664:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   6665:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   6666:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   6667:        } /* nlstate */
                   6668:        fprintf(ficgp,", '' ");
                   6669:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   6670:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6671:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6672:          if(j < nlstate)
                   6673:            fprintf(ficgp,"$%d +",k+l);
                   6674:          else
                   6675:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   6676:        }
                   6677:        fprintf(ficgp,"\nset out\n");
                   6678:       } /* end cpt state*/ 
                   6679:     } /* end covariate */  
                   6680:   } /* end nres */
1.227     brouard  6681:   
1.220     brouard  6682: /* 6eme */
1.202     brouard  6683:   /* CV preval stable (period) for each covariate */
1.237     brouard  6684:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6685:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6686:     if(TKresult[nres]!= k1)
                   6687:       continue;
1.153     brouard  6688:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6689:       
1.211     brouard  6690:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  6691:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  6692:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6693:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6694:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6695:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6696:        vlv= nbcode[Tvaraff[k]][lv];
                   6697:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6698:       }
1.237     brouard  6699:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6700:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6701:       }        
1.211     brouard  6702:       fprintf(ficgp,"\n#\n");
1.223     brouard  6703:       if(invalidvarcomb[k1]){
1.227     brouard  6704:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6705:        continue;
1.223     brouard  6706:       }
1.227     brouard  6707:       
1.241     brouard  6708:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.126     brouard  6709:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  6710: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6711:       k=3; /* Offset */
1.153     brouard  6712:       for (i=1; i<= nlstate ; i ++){
1.227     brouard  6713:        if(i==1)
                   6714:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6715:        else
                   6716:          fprintf(ficgp,", '' ");
                   6717:        l=(nlstate+ndeath)*(i-1)+1;
                   6718:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6719:        for (j=2; j<= nlstate ; j ++)
                   6720:          fprintf(ficgp,"+$%d",k+l+j-1);
                   6721:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  6722:       } /* nlstate */
1.201     brouard  6723:       fprintf(ficgp,"\nset out\n");
1.153     brouard  6724:     } /* end cpt state*/ 
                   6725:   } /* end covariate */  
1.227     brouard  6726:   
                   6727:   
1.220     brouard  6728: /* 7eme */
1.218     brouard  6729:   if(backcast == 1){
1.217     brouard  6730:     /* CV back preval stable (period) for each covariate */
1.237     brouard  6731:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6732:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6733:       if(TKresult[nres]!= k1)
                   6734:        continue;
1.218     brouard  6735:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6736:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
                   6737:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6738:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6739:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6740:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  6741:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  6742:          vlv= nbcode[Tvaraff[k]][lv];
                   6743:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6744:        }
1.237     brouard  6745:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6746:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6747:        }       
1.227     brouard  6748:        fprintf(ficgp,"\n#\n");
                   6749:        if(invalidvarcomb[k1]){
                   6750:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6751:          continue;
                   6752:        }
                   6753:        
1.241     brouard  6754:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.227     brouard  6755:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  6756: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  6757:        k=3; /* Offset */
                   6758:        for (i=1; i<= nlstate ; i ++){
                   6759:          if(i==1)
                   6760:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   6761:          else
                   6762:            fprintf(ficgp,", '' ");
                   6763:          /* l=(nlstate+ndeath)*(i-1)+1; */
                   6764:          l=(nlstate+ndeath)*(cpt-1)+1;
                   6765:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   6766:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
                   6767:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+(cpt-1)+i-1); /* a vérifier */
                   6768:          /* for (j=2; j<= nlstate ; j ++) */
                   6769:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   6770:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
                   6771:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",i,cpt);
                   6772:        } /* nlstate */
                   6773:        fprintf(ficgp,"\nset out\n");
1.218     brouard  6774:       } /* end cpt state*/ 
                   6775:     } /* end covariate */  
                   6776:   } /* End if backcast */
                   6777:   
1.223     brouard  6778:   /* 8eme */
1.218     brouard  6779:   if(prevfcast==1){
                   6780:     /* Projection from cross-sectional to stable (period) for each covariate */
                   6781:     
1.237     brouard  6782:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6783:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6784:       if(TKresult[nres]!= k1)
                   6785:        continue;
1.211     brouard  6786:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6787:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   6788:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   6789:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6790:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6791:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6792:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6793:          vlv= nbcode[Tvaraff[k]][lv];
                   6794:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6795:        }
1.237     brouard  6796:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6797:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6798:        }       
1.227     brouard  6799:        fprintf(ficgp,"\n#\n");
                   6800:        if(invalidvarcomb[k1]){
                   6801:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6802:          continue;
                   6803:        }
                   6804:        
                   6805:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  6806:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.227     brouard  6807:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  6808: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  6809:        for (i=1; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   6810:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6811:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   6812:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6813:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   6814:          if(i==1){
                   6815:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   6816:          }else{
                   6817:            fprintf(ficgp,",\\\n '' ");
                   6818:          }
                   6819:          if(cptcoveff ==0){ /* No covariate */
                   6820:            ioffset=2; /* Age is in 2 */
                   6821:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   6822:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   6823:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   6824:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   6825:            fprintf(ficgp," u %d:(", ioffset); 
                   6826:            if(i==nlstate+1)
                   6827:              fprintf(ficgp," $%d/(1.-$%d)) t 'pw.%d' with line ",      \
                   6828:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   6829:            else
                   6830:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   6831:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   6832:          }else{ /* more than 2 covariates */
                   6833:            if(cptcoveff ==1){
                   6834:              ioffset=4; /* Age is in 4 */
                   6835:            }else{
                   6836:              ioffset=6; /* Age is in 6 */
                   6837:              /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6838:              /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   6839:            }   
                   6840:            fprintf(ficgp," u %d:(",ioffset); 
                   6841:            kl=0;
                   6842:            strcpy(gplotcondition,"(");
                   6843:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   6844:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   6845:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6846:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6847:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6848:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   6849:              kl++;
                   6850:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   6851:              kl++;
                   6852:              if(k <cptcoveff && cptcoveff>1)
                   6853:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   6854:            }
                   6855:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   6856:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6857:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6858:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6859:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6860:            if(i==nlstate+1){
                   6861:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p.%d' with line ", gplotcondition, \
                   6862:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   6863:            }else{
                   6864:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   6865:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   6866:            }
                   6867:          } /* end if covariate */
                   6868:        } /* nlstate */
                   6869:        fprintf(ficgp,"\nset out\n");
1.223     brouard  6870:       } /* end cpt state*/
                   6871:     } /* end covariate */
                   6872:   } /* End if prevfcast */
1.227     brouard  6873:   
                   6874:   
1.238     brouard  6875:   /* 9eme writing MLE parameters */
                   6876:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  6877:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  6878:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  6879:     for(k=1; k <=(nlstate+ndeath); k++){
                   6880:       if (k != i) {
1.227     brouard  6881:        fprintf(ficgp,"#   current state %d\n",k);
                   6882:        for(j=1; j <=ncovmodel; j++){
                   6883:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   6884:          jk++; 
                   6885:        }
                   6886:        fprintf(ficgp,"\n");
1.126     brouard  6887:       }
                   6888:     }
1.223     brouard  6889:   }
1.187     brouard  6890:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  6891:   
1.145     brouard  6892:   /*goto avoid;*/
1.238     brouard  6893:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   6894:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  6895:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   6896:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   6897:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   6898:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   6899:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   6900:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   6901:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   6902:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   6903:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   6904:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   6905:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   6906:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   6907:   fprintf(ficgp,"#\n");
1.223     brouard  6908:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  6909:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  6910:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  6911:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.237     brouard  6912:     fprintf(ficgp,"#   jk=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   6913:     for(jk=1; jk <=m; jk++)  /* For each combination of covariate */
                   6914:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6915:       if(TKresult[nres]!= jk)
                   6916:        continue;
                   6917:       fprintf(ficgp,"# Combination of dummy  jk=%d and ",jk);
                   6918:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6919:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6920:       }        
                   6921:       fprintf(ficgp,"\n#\n");
1.241     brouard  6922:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng,nres);
1.223     brouard  6923:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   6924:       if (ng==1){
                   6925:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   6926:        fprintf(ficgp,"\nunset log y");
                   6927:       }else if (ng==2){
                   6928:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   6929:        fprintf(ficgp,"\nset log y");
                   6930:       }else if (ng==3){
                   6931:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   6932:        fprintf(ficgp,"\nset log y");
                   6933:       }else
                   6934:        fprintf(ficgp,"\nunset title ");
                   6935:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   6936:       i=1;
                   6937:       for(k2=1; k2<=nlstate; k2++) {
                   6938:        k3=i;
                   6939:        for(k=1; k<=(nlstate+ndeath); k++) {
                   6940:          if (k != k2){
                   6941:            switch( ng) {
                   6942:            case 1:
                   6943:              if(nagesqr==0)
                   6944:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   6945:              else /* nagesqr =1 */
                   6946:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   6947:              break;
                   6948:            case 2: /* ng=2 */
                   6949:              if(nagesqr==0)
                   6950:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   6951:              else /* nagesqr =1 */
                   6952:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   6953:              break;
                   6954:            case 3:
                   6955:              if(nagesqr==0)
                   6956:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   6957:              else /* nagesqr =1 */
                   6958:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   6959:              break;
                   6960:            }
                   6961:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  6962:            ijp=1; /* product no age */
                   6963:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   6964:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  6965:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.237     brouard  6966:              if(j==Tage[ij]) { /* Product by age */
                   6967:                if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
1.238     brouard  6968:                  if(DummyV[j]==0){
1.237     brouard  6969:                    fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   6970:                  }else{ /* quantitative */
                   6971:                    fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   6972:                    /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   6973:                  }
                   6974:                  ij++;
                   6975:                }
                   6976:              }else if(j==Tprod[ijp]) { /* */ 
                   6977:                /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   6978:                if(ijp <=cptcovprod) { /* Product */
1.238     brouard  6979:                  if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   6980:                    if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
1.237     brouard  6981:                      /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],nbcode[Tvard[ijp][2]][codtabm(jk,j)]); */
                   6982:                      fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   6983:                    }else{ /* Vn is dummy and Vm is quanti */
                   6984:                      /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   6985:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   6986:                    }
                   6987:                  }else{ /* Vn*Vm Vn is quanti */
1.238     brouard  6988:                    if(DummyV[Tvard[ijp][2]]==0){
1.237     brouard  6989:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   6990:                    }else{ /* Both quanti */
                   6991:                      fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   6992:                    }
                   6993:                  }
1.238     brouard  6994:                  ijp++;
1.237     brouard  6995:                }
                   6996:              } else{  /* simple covariate */
                   6997:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(jk,j)]); /\* Valgrind bug nbcode *\/ */
                   6998:                if(Dummy[j]==0){
                   6999:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7000:                }else{ /* quantitative */
                   7001:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.223     brouard  7002:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7003:                }
1.237     brouard  7004:              } /* end simple */
                   7005:            } /* end j */
1.223     brouard  7006:          }else{
                   7007:            i=i-ncovmodel;
                   7008:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7009:              fprintf(ficgp," (1.");
                   7010:          }
1.227     brouard  7011:          
1.223     brouard  7012:          if(ng != 1){
                   7013:            fprintf(ficgp,")/(1");
1.227     brouard  7014:            
1.223     brouard  7015:            for(k1=1; k1 <=nlstate; k1++){ 
                   7016:              if(nagesqr==0)
                   7017:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                   7018:              else /* nagesqr =1 */
                   7019:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1,k3+(k1-1)*ncovmodel+1+nagesqr);
1.217     brouard  7020:               
1.223     brouard  7021:              ij=1;
                   7022:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.237     brouard  7023:                if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7024:                  if(ij <=cptcovage) { /* Bug valgrind */
1.223     brouard  7025:                    fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                   7026:                    /* fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7027:                    ij++;
                   7028:                  }
                   7029:                }
                   7030:                else
1.225     brouard  7031:                  fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7032:              }
                   7033:              fprintf(ficgp,")");
                   7034:            }
                   7035:            fprintf(ficgp,")");
                   7036:            if(ng ==2)
                   7037:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   7038:            else /* ng= 3 */
                   7039:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   7040:          }else{ /* end ng <> 1 */
                   7041:            if( k !=k2) /* logit p11 is hard to draw */
                   7042:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   7043:          }
                   7044:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7045:            fprintf(ficgp,",");
                   7046:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7047:            fprintf(ficgp,",");
                   7048:          i=i+ncovmodel;
                   7049:        } /* end k */
                   7050:       } /* end k2 */
                   7051:       fprintf(ficgp,"\n set out\n");
                   7052:     } /* end jk */
                   7053:   } /* end ng */
                   7054:   /* avoid: */
                   7055:   fflush(ficgp); 
1.126     brouard  7056: }  /* end gnuplot */
                   7057: 
                   7058: 
                   7059: /*************** Moving average **************/
1.219     brouard  7060: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  7061:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  7062:    
1.222     brouard  7063:    int i, cpt, cptcod;
                   7064:    int modcovmax =1;
                   7065:    int mobilavrange, mob;
                   7066:    int iage=0;
                   7067: 
                   7068:    double sum=0.;
                   7069:    double age;
                   7070:    double *sumnewp, *sumnewm;
                   7071:    double *agemingood, *agemaxgood; /* Currently identical for all covariates */
                   7072:   
                   7073:   
1.225     brouard  7074:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  7075:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   7076: 
                   7077:    sumnewp = vector(1,ncovcombmax);
                   7078:    sumnewm = vector(1,ncovcombmax);
                   7079:    agemingood = vector(1,ncovcombmax); 
                   7080:    agemaxgood = vector(1,ncovcombmax);
                   7081: 
                   7082:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7083:      sumnewm[cptcod]=0.;
                   7084:      sumnewp[cptcod]=0.;
                   7085:      agemingood[cptcod]=0;
                   7086:      agemaxgood[cptcod]=0;
                   7087:    }
                   7088:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   7089:   
                   7090:    if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   7091:      if(mobilav==1) mobilavrange=5; /* default */
                   7092:      else mobilavrange=mobilav;
                   7093:      for (age=bage; age<=fage; age++)
                   7094:        for (i=1; i<=nlstate;i++)
                   7095:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   7096:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   7097:      /* We keep the original values on the extreme ages bage, fage and for 
                   7098:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   7099:        we use a 5 terms etc. until the borders are no more concerned. 
                   7100:      */ 
                   7101:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   7102:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
                   7103:         for (i=1; i<=nlstate;i++){
                   7104:           for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7105:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   7106:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   7107:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   7108:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   7109:             }
                   7110:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
                   7111:           }
                   7112:         }
                   7113:        }/* end age */
                   7114:      }/* end mob */
                   7115:    }else
                   7116:      return -1;
                   7117:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7118:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7119:      if(invalidvarcomb[cptcod]){
                   7120:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7121:        continue;
                   7122:      }
1.219     brouard  7123: 
1.222     brouard  7124:      agemingood[cptcod]=fage-(mob-1)/2;
                   7125:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, finding the youngest wrong */
                   7126:        sumnewm[cptcod]=0.;
                   7127:        for (i=1; i<=nlstate;i++){
                   7128:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7129:        }
                   7130:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7131:         agemingood[cptcod]=age;
                   7132:        }else{ /* bad */
                   7133:         for (i=1; i<=nlstate;i++){
                   7134:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7135:         } /* i */
                   7136:        } /* end bad */
                   7137:      }/* age */
                   7138:      sum=0.;
                   7139:      for (i=1; i<=nlstate;i++){
                   7140:        sum+=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7141:      }
                   7142:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7143:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any descending age!\n",cptcod);
                   7144:        /* for (i=1; i<=nlstate;i++){ */
                   7145:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7146:        /* } /\* i *\/ */
                   7147:      } /* end bad */
                   7148:      /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   7149:      /* From youngest, finding the oldest wrong */
                   7150:      agemaxgood[cptcod]=bage+(mob-1)/2;
                   7151:      for (age=bage+(mob-1)/2; age<=fage; age++){
                   7152:        sumnewm[cptcod]=0.;
                   7153:        for (i=1; i<=nlstate;i++){
                   7154:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7155:        }
                   7156:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7157:         agemaxgood[cptcod]=age;
                   7158:        }else{ /* bad */
                   7159:         for (i=1; i<=nlstate;i++){
                   7160:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7161:         } /* i */
                   7162:        } /* end bad */
                   7163:      }/* age */
                   7164:      sum=0.;
                   7165:      for (i=1; i<=nlstate;i++){
                   7166:        sum+=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7167:      }
                   7168:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7169:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any ascending age!\n",cptcod);
                   7170:        /* for (i=1; i<=nlstate;i++){ */
                   7171:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7172:        /* } /\* i *\/ */
                   7173:      } /* end bad */
                   7174:                
                   7175:      for (age=bage; age<=fage; age++){
1.235     brouard  7176:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  7177:        sumnewp[cptcod]=0.;
                   7178:        sumnewm[cptcod]=0.;
                   7179:        for (i=1; i<=nlstate;i++){
                   7180:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   7181:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7182:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   7183:        }
                   7184:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   7185:      }
                   7186:      /* printf("\n"); */
                   7187:      /* } */
                   7188:      /* brutal averaging */
                   7189:      for (i=1; i<=nlstate;i++){
                   7190:        for (age=1; age<=bage; age++){
                   7191:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7192:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7193:        }       
                   7194:        for (age=fage; age<=AGESUP; age++){
                   7195:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7196:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7197:        }
                   7198:      } /* end i status */
                   7199:      for (i=nlstate+1; i<=nlstate+ndeath;i++){
                   7200:        for (age=1; age<=AGESUP; age++){
                   7201:         /*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*/
                   7202:         mobaverage[(int)age][i][cptcod]=0.;
                   7203:        }
                   7204:      }
                   7205:    }/* end cptcod */
                   7206:    free_vector(sumnewm,1, ncovcombmax);
                   7207:    free_vector(sumnewp,1, ncovcombmax);
                   7208:    free_vector(agemaxgood,1, ncovcombmax);
                   7209:    free_vector(agemingood,1, ncovcombmax);
                   7210:    return 0;
                   7211:  }/* End movingaverage */
1.218     brouard  7212:  
1.126     brouard  7213: 
                   7214: /************** Forecasting ******************/
1.235     brouard  7215:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  7216:   /* proj1, year, month, day of starting projection 
                   7217:      agemin, agemax range of age
                   7218:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   7219:      anproj2 year of en of projection (same day and month as proj1).
                   7220:   */
1.235     brouard  7221:    int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  7222:   double agec; /* generic age */
                   7223:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   7224:   double *popeffectif,*popcount;
                   7225:   double ***p3mat;
1.218     brouard  7226:   /* double ***mobaverage; */
1.126     brouard  7227:   char fileresf[FILENAMELENGTH];
                   7228: 
                   7229:   agelim=AGESUP;
1.211     brouard  7230:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   7231:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   7232:      We still use firstpass and lastpass as another selection.
                   7233:   */
1.214     brouard  7234:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   7235:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  7236:  
1.201     brouard  7237:   strcpy(fileresf,"F_"); 
                   7238:   strcat(fileresf,fileresu);
1.126     brouard  7239:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   7240:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   7241:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   7242:   }
1.235     brouard  7243:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   7244:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  7245: 
1.225     brouard  7246:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  7247: 
                   7248: 
                   7249:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   7250:   if (stepm<=12) stepsize=1;
                   7251:   if(estepm < stepm){
                   7252:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   7253:   }
                   7254:   else  hstepm=estepm;   
                   7255: 
                   7256:   hstepm=hstepm/stepm; 
                   7257:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   7258:                                fractional in yp1 */
                   7259:   anprojmean=yp;
                   7260:   yp2=modf((yp1*12),&yp);
                   7261:   mprojmean=yp;
                   7262:   yp1=modf((yp2*30.5),&yp);
                   7263:   jprojmean=yp;
                   7264:   if(jprojmean==0) jprojmean=1;
                   7265:   if(mprojmean==0) jprojmean=1;
                   7266: 
1.227     brouard  7267:   i1=pow(2,cptcoveff);
1.126     brouard  7268:   if (cptcovn < 1){i1=1;}
                   7269:   
                   7270:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   7271:   
                   7272:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  7273:   
1.126     brouard  7274: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  7275:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7276:   for(k=1; k<=i1;k++){
                   7277:     if(TKresult[nres]!= k)
                   7278:       continue;
1.227     brouard  7279:     if(invalidvarcomb[k]){
                   7280:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   7281:       continue;
                   7282:     }
                   7283:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   7284:     for(j=1;j<=cptcoveff;j++) {
                   7285:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7286:     }
1.235     brouard  7287:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7288:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  7289:     }
1.227     brouard  7290:     fprintf(ficresf," yearproj age");
                   7291:     for(j=1; j<=nlstate+ndeath;j++){ 
                   7292:       for(i=1; i<=nlstate;i++)               
                   7293:        fprintf(ficresf," p%d%d",i,j);
                   7294:       fprintf(ficresf," wp.%d",j);
                   7295:     }
                   7296:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   7297:       fprintf(ficresf,"\n");
                   7298:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
                   7299:       for (agec=fage; agec>=(ageminpar-1); agec--){ 
                   7300:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   7301:        nhstepm = nhstepm/hstepm; 
                   7302:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7303:        oldm=oldms;savm=savms;
1.235     brouard  7304:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.227     brouard  7305:        
                   7306:        for (h=0; h<=nhstepm; h++){
                   7307:          if (h*hstepm/YEARM*stepm ==yearp) {
                   7308:            fprintf(ficresf,"\n");
                   7309:            for(j=1;j<=cptcoveff;j++) 
                   7310:              fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7311:            fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   7312:          } 
                   7313:          for(j=1; j<=nlstate+ndeath;j++) {
                   7314:            ppij=0.;
                   7315:            for(i=1; i<=nlstate;i++) {
                   7316:              if (mobilav==1) 
                   7317:                ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][k];
                   7318:              else {
                   7319:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   7320:              }
                   7321:              if (h*hstepm/YEARM*stepm== yearp) {
                   7322:                fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   7323:              }
                   7324:            } /* end i */
                   7325:            if (h*hstepm/YEARM*stepm==yearp) {
                   7326:              fprintf(ficresf," %.3f", ppij);
                   7327:            }
                   7328:          }/* end j */
                   7329:        } /* end h */
                   7330:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7331:       } /* end agec */
                   7332:     } /* end yearp */
                   7333:   } /* end  k */
1.219     brouard  7334:        
1.126     brouard  7335:   fclose(ficresf);
1.215     brouard  7336:   printf("End of Computing forecasting \n");
                   7337:   fprintf(ficlog,"End of Computing forecasting\n");
                   7338: 
1.126     brouard  7339: }
                   7340: 
1.218     brouard  7341: /* /\************** Back Forecasting ******************\/ */
1.225     brouard  7342: /* void prevbackforecast(char fileres[], double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
1.218     brouard  7343: /*   /\* back1, year, month, day of starting backection  */
                   7344: /*      agemin, agemax range of age */
                   7345: /*      dateprev1 dateprev2 range of dates during which prevalence is computed */
                   7346: /*      anback2 year of en of backection (same day and month as back1). */
                   7347: /*   *\/ */
                   7348: /*   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1; */
                   7349: /*   double agec; /\* generic age *\/ */
                   7350: /*   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean; */
                   7351: /*   double *popeffectif,*popcount; */
                   7352: /*   double ***p3mat; */
                   7353: /*   /\* double ***mobaverage; *\/ */
                   7354: /*   char fileresfb[FILENAMELENGTH]; */
                   7355:        
                   7356: /*   agelim=AGESUP; */
                   7357: /*   /\* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people */
                   7358: /*      in each health status at the date of interview (if between dateprev1 and dateprev2). */
                   7359: /*      We still use firstpass and lastpass as another selection. */
                   7360: /*   *\/ */
                   7361: /*   /\* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ *\/ */
                   7362: /*   /\*             firstpass, lastpass,  stepm,  weightopt, model); *\/ */
                   7363: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   7364:        
                   7365: /*   strcpy(fileresfb,"FB_");  */
                   7366: /*   strcat(fileresfb,fileresu); */
                   7367: /*   if((ficresfb=fopen(fileresfb,"w"))==NULL) { */
                   7368: /*     printf("Problem with back forecast resultfile: %s\n", fileresfb); */
                   7369: /*     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb); */
                   7370: /*   } */
                   7371: /*   printf("Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7372: /*   fprintf(ficlog,"Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7373:        
1.225     brouard  7374: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.218     brouard  7375:        
                   7376: /*   /\* if (mobilav!=0) { *\/ */
                   7377: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7378: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7379: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7380: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7381: /*   /\*   } *\/ */
                   7382: /*   /\* } *\/ */
                   7383:        
                   7384: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7385: /*   if (stepm<=12) stepsize=1; */
                   7386: /*   if(estepm < stepm){ */
                   7387: /*     printf ("Problem %d lower than %d\n",estepm, stepm); */
                   7388: /*   } */
                   7389: /*   else  hstepm=estepm;    */
                   7390:        
                   7391: /*   hstepm=hstepm/stepm;  */
                   7392: /*   yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   7393: /*                                fractional in yp1 *\/ */
                   7394: /*   anprojmean=yp; */
                   7395: /*   yp2=modf((yp1*12),&yp); */
                   7396: /*   mprojmean=yp; */
                   7397: /*   yp1=modf((yp2*30.5),&yp); */
                   7398: /*   jprojmean=yp; */
                   7399: /*   if(jprojmean==0) jprojmean=1; */
                   7400: /*   if(mprojmean==0) jprojmean=1; */
                   7401:        
1.225     brouard  7402: /*   i1=cptcoveff; */
1.218     brouard  7403: /*   if (cptcovn < 1){i1=1;} */
1.217     brouard  7404:   
1.218     brouard  7405: /*   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);  */
1.217     brouard  7406:   
1.218     brouard  7407: /*   fprintf(ficresfb,"#****** Routine prevbackforecast **\n"); */
                   7408:        
                   7409: /*     /\*           if (h==(int)(YEARM*yearp)){ *\/ */
                   7410: /*   for(cptcov=1, k=0;cptcov<=i1;cptcov++){ */
1.225     brouard  7411: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
1.218     brouard  7412: /*       k=k+1; */
                   7413: /*       fprintf(ficresfb,"\n#****** hbijx=probability over h years, hp.jx is weighted by observed prev \n#"); */
1.225     brouard  7414: /*       for(j=1;j<=cptcoveff;j++) { */
1.218     brouard  7415: /*                             fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7416: /*       } */
                   7417: /*       fprintf(ficresfb," yearbproj age"); */
                   7418: /*       for(j=1; j<=nlstate+ndeath;j++){  */
                   7419: /*                             for(i=1; i<=nlstate;i++)               */
                   7420: /*           fprintf(ficresfb," p%d%d",i,j); */
                   7421: /*                             fprintf(ficresfb," p.%d",j); */
                   7422: /*       } */
                   7423: /*       for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {  */
                   7424: /*                             /\* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  *\/ */
                   7425: /*                             fprintf(ficresfb,"\n"); */
                   7426: /*                             fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);    */
                   7427: /*                             for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   7428: /*                                     nhstepm=(int) rint((agelim-agec)*YEARM/stepm);  */
                   7429: /*                                     nhstepm = nhstepm/hstepm;  */
                   7430: /*                                     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7431: /*                                     oldm=oldms;savm=savms; */
                   7432: /*                                     hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm,oldm,savm, dnewm, doldm, dsavm, k);       */
                   7433: /*                                     for (h=0; h<=nhstepm; h++){ */
                   7434: /*                                             if (h*hstepm/YEARM*stepm ==yearp) { */
                   7435: /*               fprintf(ficresfb,"\n"); */
1.225     brouard  7436: /*               for(j=1;j<=cptcoveff;j++)  */
1.218     brouard  7437: /*                 fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7438: /*                                                     fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec+h*hstepm/YEARM*stepm); */
                   7439: /*                                             }  */
                   7440: /*                                             for(j=1; j<=nlstate+ndeath;j++) { */
                   7441: /*                                                     ppij=0.; */
                   7442: /*                                                     for(i=1; i<=nlstate;i++) { */
                   7443: /*                                                             if (mobilav==1)  */
                   7444: /*                                                                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod]; */
                   7445: /*                                                             else { */
                   7446: /*                                                                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod]; */
                   7447: /*                                                             } */
                   7448: /*                                                             if (h*hstepm/YEARM*stepm== yearp) { */
                   7449: /*                                                                     fprintf(ficresfb," %.3f", p3mat[i][j][h]); */
                   7450: /*                                                             } */
                   7451: /*                                                     } /\* end i *\/ */
                   7452: /*                                                     if (h*hstepm/YEARM*stepm==yearp) { */
                   7453: /*                                                             fprintf(ficresfb," %.3f", ppij); */
                   7454: /*                                                     } */
                   7455: /*                                             }/\* end j *\/ */
                   7456: /*                                     } /\* end h *\/ */
                   7457: /*                                     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7458: /*                             } /\* end agec *\/ */
                   7459: /*       } /\* end yearp *\/ */
                   7460: /*     } /\* end cptcod *\/ */
                   7461: /*   } /\* end  cptcov *\/ */
                   7462:        
                   7463: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7464:        
                   7465: /*   fclose(ficresfb); */
                   7466: /*   printf("End of Computing Back forecasting \n"); */
                   7467: /*   fprintf(ficlog,"End of Computing Back forecasting\n"); */
1.217     brouard  7468:        
1.218     brouard  7469: /* } */
1.217     brouard  7470: 
1.126     brouard  7471: /************** Forecasting *****not tested NB*************/
1.227     brouard  7472: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  7473:   
1.227     brouard  7474: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   7475: /*   int *popage; */
                   7476: /*   double calagedatem, agelim, kk1, kk2; */
                   7477: /*   double *popeffectif,*popcount; */
                   7478: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   7479: /*   /\* double ***mobaverage; *\/ */
                   7480: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  7481: 
1.227     brouard  7482: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7483: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7484: /*   agelim=AGESUP; */
                   7485: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  7486:   
1.227     brouard  7487: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  7488:   
                   7489:   
1.227     brouard  7490: /*   strcpy(filerespop,"POP_");  */
                   7491: /*   strcat(filerespop,fileresu); */
                   7492: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   7493: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   7494: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   7495: /*   } */
                   7496: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   7497: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  7498: 
1.227     brouard  7499: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  7500: 
1.227     brouard  7501: /*   /\* if (mobilav!=0) { *\/ */
                   7502: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7503: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7504: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7505: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7506: /*   /\*   } *\/ */
                   7507: /*   /\* } *\/ */
1.126     brouard  7508: 
1.227     brouard  7509: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7510: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  7511:   
1.227     brouard  7512: /*   agelim=AGESUP; */
1.126     brouard  7513:   
1.227     brouard  7514: /*   hstepm=1; */
                   7515: /*   hstepm=hstepm/stepm;  */
1.218     brouard  7516:        
1.227     brouard  7517: /*   if (popforecast==1) { */
                   7518: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   7519: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   7520: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   7521: /*     }  */
                   7522: /*     popage=ivector(0,AGESUP); */
                   7523: /*     popeffectif=vector(0,AGESUP); */
                   7524: /*     popcount=vector(0,AGESUP); */
1.126     brouard  7525:     
1.227     brouard  7526: /*     i=1;    */
                   7527: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  7528:     
1.227     brouard  7529: /*     imx=i; */
                   7530: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   7531: /*   } */
1.218     brouard  7532:   
1.227     brouard  7533: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   7534: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   7535: /*       k=k+1; */
                   7536: /*       fprintf(ficrespop,"\n#******"); */
                   7537: /*       for(j=1;j<=cptcoveff;j++) { */
                   7538: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7539: /*       } */
                   7540: /*       fprintf(ficrespop,"******\n"); */
                   7541: /*       fprintf(ficrespop,"# Age"); */
                   7542: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   7543: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  7544:       
1.227     brouard  7545: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   7546: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  7547:        
1.227     brouard  7548: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7549: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7550: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7551:          
1.227     brouard  7552: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7553: /*       oldm=oldms;savm=savms; */
                   7554: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  7555:          
1.227     brouard  7556: /*       for (h=0; h<=nhstepm; h++){ */
                   7557: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7558: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7559: /*         }  */
                   7560: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7561: /*           kk1=0.;kk2=0; */
                   7562: /*           for(i=1; i<=nlstate;i++) {               */
                   7563: /*             if (mobilav==1)  */
                   7564: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   7565: /*             else { */
                   7566: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   7567: /*             } */
                   7568: /*           } */
                   7569: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   7570: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   7571: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   7572: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   7573: /*           } */
                   7574: /*         } */
                   7575: /*         for(i=1; i<=nlstate;i++){ */
                   7576: /*           kk1=0.; */
                   7577: /*           for(j=1; j<=nlstate;j++){ */
                   7578: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   7579: /*           } */
                   7580: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   7581: /*         } */
1.218     brouard  7582:            
1.227     brouard  7583: /*         if (h==(int)(calagedatem+12*cpt)) */
                   7584: /*           for(j=1; j<=nlstate;j++)  */
                   7585: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   7586: /*       } */
                   7587: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7588: /*     } */
                   7589: /*       } */
1.218     brouard  7590:       
1.227     brouard  7591: /*       /\******\/ */
1.218     brouard  7592:       
1.227     brouard  7593: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   7594: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   7595: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7596: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7597: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7598:          
1.227     brouard  7599: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7600: /*       oldm=oldms;savm=savms; */
                   7601: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   7602: /*       for (h=0; h<=nhstepm; h++){ */
                   7603: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7604: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7605: /*         }  */
                   7606: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7607: /*           kk1=0.;kk2=0; */
                   7608: /*           for(i=1; i<=nlstate;i++) {               */
                   7609: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   7610: /*           } */
                   7611: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   7612: /*         } */
                   7613: /*       } */
                   7614: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7615: /*     } */
                   7616: /*       } */
                   7617: /*     }  */
                   7618: /*   } */
1.218     brouard  7619:   
1.227     brouard  7620: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  7621:   
1.227     brouard  7622: /*   if (popforecast==1) { */
                   7623: /*     free_ivector(popage,0,AGESUP); */
                   7624: /*     free_vector(popeffectif,0,AGESUP); */
                   7625: /*     free_vector(popcount,0,AGESUP); */
                   7626: /*   } */
                   7627: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7628: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7629: /*   fclose(ficrespop); */
                   7630: /* } /\* End of popforecast *\/ */
1.218     brouard  7631:  
1.126     brouard  7632: int fileappend(FILE *fichier, char *optionfich)
                   7633: {
                   7634:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   7635:     printf("Problem with file: %s\n", optionfich);
                   7636:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   7637:     return (0);
                   7638:   }
                   7639:   fflush(fichier);
                   7640:   return (1);
                   7641: }
                   7642: 
                   7643: 
                   7644: /**************** function prwizard **********************/
                   7645: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   7646: {
                   7647: 
                   7648:   /* Wizard to print covariance matrix template */
                   7649: 
1.164     brouard  7650:   char ca[32], cb[32];
                   7651:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  7652:   int numlinepar;
                   7653: 
                   7654:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7655:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7656:   for(i=1; i <=nlstate; i++){
                   7657:     jj=0;
                   7658:     for(j=1; j <=nlstate+ndeath; j++){
                   7659:       if(j==i) continue;
                   7660:       jj++;
                   7661:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   7662:       printf("%1d%1d",i,j);
                   7663:       fprintf(ficparo,"%1d%1d",i,j);
                   7664:       for(k=1; k<=ncovmodel;k++){
                   7665:        /*        printf(" %lf",param[i][j][k]); */
                   7666:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   7667:        printf(" 0.");
                   7668:        fprintf(ficparo," 0.");
                   7669:       }
                   7670:       printf("\n");
                   7671:       fprintf(ficparo,"\n");
                   7672:     }
                   7673:   }
                   7674:   printf("# Scales (for hessian or gradient estimation)\n");
                   7675:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   7676:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   7677:   for(i=1; i <=nlstate; i++){
                   7678:     jj=0;
                   7679:     for(j=1; j <=nlstate+ndeath; j++){
                   7680:       if(j==i) continue;
                   7681:       jj++;
                   7682:       fprintf(ficparo,"%1d%1d",i,j);
                   7683:       printf("%1d%1d",i,j);
                   7684:       fflush(stdout);
                   7685:       for(k=1; k<=ncovmodel;k++){
                   7686:        /*      printf(" %le",delti3[i][j][k]); */
                   7687:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   7688:        printf(" 0.");
                   7689:        fprintf(ficparo," 0.");
                   7690:       }
                   7691:       numlinepar++;
                   7692:       printf("\n");
                   7693:       fprintf(ficparo,"\n");
                   7694:     }
                   7695:   }
                   7696:   printf("# Covariance matrix\n");
                   7697: /* # 121 Var(a12)\n\ */
                   7698: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7699: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   7700: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   7701: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   7702: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   7703: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   7704: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   7705:   fflush(stdout);
                   7706:   fprintf(ficparo,"# Covariance matrix\n");
                   7707:   /* # 121 Var(a12)\n\ */
                   7708:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7709:   /* #   ...\n\ */
                   7710:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   7711:   
                   7712:   for(itimes=1;itimes<=2;itimes++){
                   7713:     jj=0;
                   7714:     for(i=1; i <=nlstate; i++){
                   7715:       for(j=1; j <=nlstate+ndeath; j++){
                   7716:        if(j==i) continue;
                   7717:        for(k=1; k<=ncovmodel;k++){
                   7718:          jj++;
                   7719:          ca[0]= k+'a'-1;ca[1]='\0';
                   7720:          if(itimes==1){
                   7721:            printf("#%1d%1d%d",i,j,k);
                   7722:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   7723:          }else{
                   7724:            printf("%1d%1d%d",i,j,k);
                   7725:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   7726:            /*  printf(" %.5le",matcov[i][j]); */
                   7727:          }
                   7728:          ll=0;
                   7729:          for(li=1;li <=nlstate; li++){
                   7730:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   7731:              if(lj==li) continue;
                   7732:              for(lk=1;lk<=ncovmodel;lk++){
                   7733:                ll++;
                   7734:                if(ll<=jj){
                   7735:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   7736:                  if(ll<jj){
                   7737:                    if(itimes==1){
                   7738:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7739:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7740:                    }else{
                   7741:                      printf(" 0.");
                   7742:                      fprintf(ficparo," 0.");
                   7743:                    }
                   7744:                  }else{
                   7745:                    if(itimes==1){
                   7746:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   7747:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   7748:                    }else{
                   7749:                      printf(" 0.");
                   7750:                      fprintf(ficparo," 0.");
                   7751:                    }
                   7752:                  }
                   7753:                }
                   7754:              } /* end lk */
                   7755:            } /* end lj */
                   7756:          } /* end li */
                   7757:          printf("\n");
                   7758:          fprintf(ficparo,"\n");
                   7759:          numlinepar++;
                   7760:        } /* end k*/
                   7761:       } /*end j */
                   7762:     } /* end i */
                   7763:   } /* end itimes */
                   7764: 
                   7765: } /* end of prwizard */
                   7766: /******************* Gompertz Likelihood ******************************/
                   7767: double gompertz(double x[])
                   7768: { 
                   7769:   double A,B,L=0.0,sump=0.,num=0.;
                   7770:   int i,n=0; /* n is the size of the sample */
                   7771: 
1.220     brouard  7772:   for (i=1;i<=imx ; i++) {
1.126     brouard  7773:     sump=sump+weight[i];
                   7774:     /*    sump=sump+1;*/
                   7775:     num=num+1;
                   7776:   }
                   7777:  
                   7778:  
                   7779:   /* for (i=0; i<=imx; i++) 
                   7780:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   7781: 
                   7782:   for (i=1;i<=imx ; i++)
                   7783:     {
                   7784:       if (cens[i] == 1 && wav[i]>1)
                   7785:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   7786:       
                   7787:       if (cens[i] == 0 && wav[i]>1)
                   7788:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   7789:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   7790:       
                   7791:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   7792:       if (wav[i] > 1 ) { /* ??? */
                   7793:        L=L+A*weight[i];
                   7794:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   7795:       }
                   7796:     }
                   7797: 
                   7798:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   7799:  
                   7800:   return -2*L*num/sump;
                   7801: }
                   7802: 
1.136     brouard  7803: #ifdef GSL
                   7804: /******************* Gompertz_f Likelihood ******************************/
                   7805: double gompertz_f(const gsl_vector *v, void *params)
                   7806: { 
                   7807:   double A,B,LL=0.0,sump=0.,num=0.;
                   7808:   double *x= (double *) v->data;
                   7809:   int i,n=0; /* n is the size of the sample */
                   7810: 
                   7811:   for (i=0;i<=imx-1 ; i++) {
                   7812:     sump=sump+weight[i];
                   7813:     /*    sump=sump+1;*/
                   7814:     num=num+1;
                   7815:   }
                   7816:  
                   7817:  
                   7818:   /* for (i=0; i<=imx; i++) 
                   7819:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   7820:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   7821:   for (i=1;i<=imx ; i++)
                   7822:     {
                   7823:       if (cens[i] == 1 && wav[i]>1)
                   7824:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   7825:       
                   7826:       if (cens[i] == 0 && wav[i]>1)
                   7827:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   7828:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   7829:       
                   7830:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   7831:       if (wav[i] > 1 ) { /* ??? */
                   7832:        LL=LL+A*weight[i];
                   7833:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   7834:       }
                   7835:     }
                   7836: 
                   7837:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   7838:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   7839:  
                   7840:   return -2*LL*num/sump;
                   7841: }
                   7842: #endif
                   7843: 
1.126     brouard  7844: /******************* Printing html file ***********/
1.201     brouard  7845: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  7846:                  int lastpass, int stepm, int weightopt, char model[],\
                   7847:                  int imx,  double p[],double **matcov,double agemortsup){
                   7848:   int i,k;
                   7849: 
                   7850:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   7851:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   7852:   for (i=1;i<=2;i++) 
                   7853:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  7854:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  7855:   fprintf(fichtm,"</ul>");
                   7856: 
                   7857: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   7858: 
                   7859:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   7860: 
                   7861:  for (k=agegomp;k<(agemortsup-2);k++) 
                   7862:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   7863: 
                   7864:  
                   7865:   fflush(fichtm);
                   7866: }
                   7867: 
                   7868: /******************* Gnuplot file **************/
1.201     brouard  7869: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  7870: 
                   7871:   char dirfileres[132],optfileres[132];
1.164     brouard  7872: 
1.126     brouard  7873:   int ng;
                   7874: 
                   7875: 
                   7876:   /*#ifdef windows */
                   7877:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   7878:     /*#endif */
                   7879: 
                   7880: 
                   7881:   strcpy(dirfileres,optionfilefiname);
                   7882:   strcpy(optfileres,"vpl");
1.199     brouard  7883:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  7884:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  7885:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  7886:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  7887:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   7888: 
                   7889: } 
                   7890: 
1.136     brouard  7891: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   7892: {
1.126     brouard  7893: 
1.136     brouard  7894:   /*-------- data file ----------*/
                   7895:   FILE *fic;
                   7896:   char dummy[]="                         ";
1.240     brouard  7897:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  7898:   int lstra;
1.136     brouard  7899:   int linei, month, year,iout;
                   7900:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  7901:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  7902:   char *stratrunc;
1.223     brouard  7903: 
1.240     brouard  7904:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   7905:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  7906: 
1.240     brouard  7907:   for(v=1; v <=ncovcol;v++){
                   7908:     DummyV[v]=0;
                   7909:     FixedV[v]=0;
                   7910:   }
                   7911:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   7912:     DummyV[v]=1;
                   7913:     FixedV[v]=0;
                   7914:   }
                   7915:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   7916:     DummyV[v]=0;
                   7917:     FixedV[v]=1;
                   7918:   }
                   7919:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   7920:     DummyV[v]=1;
                   7921:     FixedV[v]=1;
                   7922:   }
                   7923:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   7924:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   7925:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   7926:   }
1.126     brouard  7927: 
1.136     brouard  7928:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  7929:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   7930:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  7931:   }
1.126     brouard  7932: 
1.136     brouard  7933:   i=1;
                   7934:   linei=0;
                   7935:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   7936:     linei=linei+1;
                   7937:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   7938:       if(line[j] == '\t')
                   7939:        line[j] = ' ';
                   7940:     }
                   7941:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   7942:       ;
                   7943:     };
                   7944:     line[j+1]=0;  /* Trims blanks at end of line */
                   7945:     if(line[0]=='#'){
                   7946:       fprintf(ficlog,"Comment line\n%s\n",line);
                   7947:       printf("Comment line\n%s\n",line);
                   7948:       continue;
                   7949:     }
                   7950:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  7951:     strcpy(line, linetmp);
1.223     brouard  7952:     
                   7953:     /* Loops on waves */
                   7954:     for (j=maxwav;j>=1;j--){
                   7955:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  7956:        cutv(stra, strb, line, ' '); 
                   7957:        if(strb[0]=='.') { /* Missing value */
                   7958:          lval=-1;
                   7959:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   7960:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   7961:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   7962:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   7963:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   7964:            return 1;
                   7965:          }
                   7966:        }else{
                   7967:          errno=0;
                   7968:          /* what_kind_of_number(strb); */
                   7969:          dval=strtod(strb,&endptr); 
                   7970:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   7971:          /* if(strb != endptr && *endptr == '\0') */
                   7972:          /*    dval=dlval; */
                   7973:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   7974:          if( strb[0]=='\0' || (*endptr != '\0')){
                   7975:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   7976:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   7977:            return 1;
                   7978:          }
                   7979:          cotqvar[j][iv][i]=dval; 
                   7980:          cotvar[j][ntv+iv][i]=dval; 
                   7981:        }
                   7982:        strcpy(line,stra);
1.223     brouard  7983:       }/* end loop ntqv */
1.225     brouard  7984:       
1.223     brouard  7985:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  7986:        cutv(stra, strb, line, ' '); 
                   7987:        if(strb[0]=='.') { /* Missing value */
                   7988:          lval=-1;
                   7989:        }else{
                   7990:          errno=0;
                   7991:          lval=strtol(strb,&endptr,10); 
                   7992:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   7993:          if( strb[0]=='\0' || (*endptr != '\0')){
                   7994:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   7995:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   7996:            return 1;
                   7997:          }
                   7998:        }
                   7999:        if(lval <-1 || lval >1){
                   8000:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8001:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8002:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8003:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8004:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8005:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8006:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8007:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8008:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  8009:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8010:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8011:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8012:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8013:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8014:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8015:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8016:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8017:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  8018:          return 1;
                   8019:        }
                   8020:        cotvar[j][iv][i]=(double)(lval);
                   8021:        strcpy(line,stra);
1.223     brouard  8022:       }/* end loop ntv */
1.225     brouard  8023:       
1.223     brouard  8024:       /* Statuses  at wave */
1.137     brouard  8025:       cutv(stra, strb, line, ' '); 
1.223     brouard  8026:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  8027:        lval=-1;
1.136     brouard  8028:       }else{
1.238     brouard  8029:        errno=0;
                   8030:        lval=strtol(strb,&endptr,10); 
                   8031:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8032:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8033:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   8034:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   8035:          return 1;
                   8036:        }
1.136     brouard  8037:       }
1.225     brouard  8038:       
1.136     brouard  8039:       s[j][i]=lval;
1.225     brouard  8040:       
1.223     brouard  8041:       /* Date of Interview */
1.136     brouard  8042:       strcpy(line,stra);
                   8043:       cutv(stra, strb,line,' ');
1.169     brouard  8044:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8045:       }
1.169     brouard  8046:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  8047:        month=99;
                   8048:        year=9999;
1.136     brouard  8049:       }else{
1.225     brouard  8050:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   8051:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   8052:        return 1;
1.136     brouard  8053:       }
                   8054:       anint[j][i]= (double) year; 
                   8055:       mint[j][i]= (double)month; 
                   8056:       strcpy(line,stra);
1.223     brouard  8057:     } /* End loop on waves */
1.225     brouard  8058:     
1.223     brouard  8059:     /* Date of death */
1.136     brouard  8060:     cutv(stra, strb,line,' '); 
1.169     brouard  8061:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8062:     }
1.169     brouard  8063:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  8064:       month=99;
                   8065:       year=9999;
                   8066:     }else{
1.141     brouard  8067:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  8068:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   8069:       return 1;
1.136     brouard  8070:     }
                   8071:     andc[i]=(double) year; 
                   8072:     moisdc[i]=(double) month; 
                   8073:     strcpy(line,stra);
                   8074:     
1.223     brouard  8075:     /* Date of birth */
1.136     brouard  8076:     cutv(stra, strb,line,' '); 
1.169     brouard  8077:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8078:     }
1.169     brouard  8079:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  8080:       month=99;
                   8081:       year=9999;
                   8082:     }else{
1.141     brouard  8083:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   8084:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8085:       return 1;
1.136     brouard  8086:     }
                   8087:     if (year==9999) {
1.141     brouard  8088:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   8089:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8090:       return 1;
                   8091:       
1.136     brouard  8092:     }
                   8093:     annais[i]=(double)(year);
                   8094:     moisnais[i]=(double)(month); 
                   8095:     strcpy(line,stra);
1.225     brouard  8096:     
1.223     brouard  8097:     /* Sample weight */
1.136     brouard  8098:     cutv(stra, strb,line,' '); 
                   8099:     errno=0;
                   8100:     dval=strtod(strb,&endptr); 
                   8101:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  8102:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   8103:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  8104:       fflush(ficlog);
                   8105:       return 1;
                   8106:     }
                   8107:     weight[i]=dval; 
                   8108:     strcpy(line,stra);
1.225     brouard  8109:     
1.223     brouard  8110:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   8111:       cutv(stra, strb, line, ' '); 
                   8112:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  8113:        lval=-1;
1.223     brouard  8114:       }else{
1.225     brouard  8115:        errno=0;
                   8116:        /* what_kind_of_number(strb); */
                   8117:        dval=strtod(strb,&endptr);
                   8118:        /* if(strb != endptr && *endptr == '\0') */
                   8119:        /*   dval=dlval; */
                   8120:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8121:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8122:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   8123:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   8124:          return 1;
                   8125:        }
                   8126:        coqvar[iv][i]=dval; 
1.226     brouard  8127:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  8128:       }
                   8129:       strcpy(line,stra);
                   8130:     }/* end loop nqv */
1.136     brouard  8131:     
1.223     brouard  8132:     /* Covariate values */
1.136     brouard  8133:     for (j=ncovcol;j>=1;j--){
                   8134:       cutv(stra, strb,line,' '); 
1.223     brouard  8135:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  8136:        lval=-1;
1.136     brouard  8137:       }else{
1.225     brouard  8138:        errno=0;
                   8139:        lval=strtol(strb,&endptr,10); 
                   8140:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8141:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   8142:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   8143:          return 1;
                   8144:        }
1.136     brouard  8145:       }
                   8146:       if(lval <-1 || lval >1){
1.225     brouard  8147:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8148:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8149:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8150:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8151:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8152:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8153:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8154:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8155:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  8156:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8157:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8158:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8159:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8160:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8161:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8162:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8163:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8164:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  8165:        return 1;
1.136     brouard  8166:       }
                   8167:       covar[j][i]=(double)(lval);
                   8168:       strcpy(line,stra);
                   8169:     }  
                   8170:     lstra=strlen(stra);
1.225     brouard  8171:     
1.136     brouard  8172:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   8173:       stratrunc = &(stra[lstra-9]);
                   8174:       num[i]=atol(stratrunc);
                   8175:     }
                   8176:     else
                   8177:       num[i]=atol(stra);
                   8178:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   8179:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   8180:     
                   8181:     i=i+1;
                   8182:   } /* End loop reading  data */
1.225     brouard  8183:   
1.136     brouard  8184:   *imax=i-1; /* Number of individuals */
                   8185:   fclose(fic);
1.225     brouard  8186:   
1.136     brouard  8187:   return (0);
1.164     brouard  8188:   /* endread: */
1.225     brouard  8189:   printf("Exiting readdata: ");
                   8190:   fclose(fic);
                   8191:   return (1);
1.223     brouard  8192: }
1.126     brouard  8193: 
1.234     brouard  8194: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  8195:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  8196:   while (*p2 == ' ')
1.234     brouard  8197:     p2++; 
                   8198:   /* while ((*p1++ = *p2++) !=0) */
                   8199:   /*   ; */
                   8200:   /* do */
                   8201:   /*   while (*p2 == ' ') */
                   8202:   /*     p2++; */
                   8203:   /* while (*p1++ == *p2++); */
                   8204:   *stri=p2; 
1.145     brouard  8205: }
                   8206: 
1.235     brouard  8207: int decoderesult ( char resultline[], int nres)
1.230     brouard  8208: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   8209: {
1.235     brouard  8210:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  8211:   char resultsav[MAXLINE];
1.234     brouard  8212:   int resultmodel[MAXLINE];
                   8213:   int modelresult[MAXLINE];
1.230     brouard  8214:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   8215: 
1.234     brouard  8216:   removefirstspace(&resultline);
1.233     brouard  8217:   printf("decoderesult:%s\n",resultline);
1.230     brouard  8218: 
                   8219:   if (strstr(resultline,"v") !=0){
                   8220:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   8221:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   8222:     return 1;
                   8223:   }
                   8224:   trimbb(resultsav, resultline);
                   8225:   if (strlen(resultsav) >1){
                   8226:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   8227:   }
1.234     brouard  8228:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   8229:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8230:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8231:   }
                   8232:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   8233:     if(nbocc(resultsav,'=') >1){
                   8234:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   8235:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   8236:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   8237:     }else
                   8238:       cutl(strc,strd,resultsav,'=');
1.230     brouard  8239:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  8240:     
1.230     brouard  8241:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   8242:     Tvarsel[k]=atoi(strc);
                   8243:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   8244:     /* cptcovsel++;     */
                   8245:     if (nbocc(stra,'=') >0)
                   8246:       strcpy(resultsav,stra); /* and analyzes it */
                   8247:   }
1.235     brouard  8248:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  8249:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8250:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  8251:       match=0;
1.236     brouard  8252:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  8253:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  8254:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  8255:          match=1;
                   8256:          break;
                   8257:        }
                   8258:       }
                   8259:       if(match == 0){
                   8260:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8261:       }
                   8262:     }
                   8263:   }
1.235     brouard  8264:   /* Checking for missing or useless values in comparison of current model needs */
                   8265:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  8266:     match=0;
1.235     brouard  8267:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8268:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  8269:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  8270:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  8271:          ++match;
                   8272:        }
                   8273:       }
                   8274:     }
                   8275:     if(match == 0){
                   8276:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8277:     }else if(match > 1){
                   8278:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   8279:     }
                   8280:   }
1.235     brouard  8281:       
1.234     brouard  8282:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  8283:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8284:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   8285:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   8286:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   8287:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   8288:   /*    1 0 0 0 */
                   8289:   /*    2 1 0 0 */
                   8290:   /*    3 0 1 0 */ 
                   8291:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   8292:   /*    5 0 0 1 */
                   8293:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   8294:   /*    7 0 1 1 */
                   8295:   /*    8 1 1 1 */
1.237     brouard  8296:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   8297:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   8298:   /* V5*age V5 known which value for nres?  */
                   8299:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  8300:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   8301:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  8302:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  8303:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   8304:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  8305:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   8306:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   8307:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  8308:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   8309:       k4++;;
                   8310:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   8311:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   8312:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  8313:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   8314:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   8315:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  8316:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   8317:       k4q++;;
                   8318:     }
                   8319:   }
1.234     brouard  8320:   
1.235     brouard  8321:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  8322:   return (0);
                   8323: }
1.235     brouard  8324: 
1.230     brouard  8325: int decodemodel( char model[], int lastobs)
                   8326:  /**< This routine decodes the model and returns:
1.224     brouard  8327:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   8328:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   8329:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   8330:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   8331:        * - cptcovage number of covariates with age*products =2
                   8332:        * - cptcovs number of simple covariates
                   8333:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   8334:        *     which is a new column after the 9 (ncovcol) variables. 
                   8335:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   8336:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   8337:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   8338:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   8339:        */
1.136     brouard  8340: {
1.238     brouard  8341:   int i, j, k, ks, v;
1.227     brouard  8342:   int  j1, k1, k2, k3, k4;
1.136     brouard  8343:   char modelsav[80];
1.145     brouard  8344:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  8345:   char *strpt;
1.136     brouard  8346: 
1.145     brouard  8347:   /*removespace(model);*/
1.136     brouard  8348:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  8349:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  8350:     if (strstr(model,"AGE") !=0){
1.192     brouard  8351:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   8352:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  8353:       return 1;
                   8354:     }
1.141     brouard  8355:     if (strstr(model,"v") !=0){
                   8356:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   8357:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   8358:       return 1;
                   8359:     }
1.187     brouard  8360:     strcpy(modelsav,model); 
                   8361:     if ((strpt=strstr(model,"age*age")) !=0){
                   8362:       printf(" strpt=%s, model=%s\n",strpt, model);
                   8363:       if(strpt != model){
1.234     brouard  8364:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8365:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8366:  corresponding column of parameters.\n",model);
1.234     brouard  8367:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8368:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8369:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  8370:        return 1;
1.225     brouard  8371:       }
1.187     brouard  8372:       nagesqr=1;
                   8373:       if (strstr(model,"+age*age") !=0)
1.234     brouard  8374:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  8375:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  8376:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  8377:       else 
1.234     brouard  8378:        substrchaine(modelsav, model, "age*age");
1.187     brouard  8379:     }else
                   8380:       nagesqr=0;
                   8381:     if (strlen(modelsav) >1){
                   8382:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   8383:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  8384:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  8385:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  8386:                     * cst, age and age*age 
                   8387:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   8388:       /* including age products which are counted in cptcovage.
                   8389:        * but the covariates which are products must be treated 
                   8390:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  8391:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   8392:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  8393:       
                   8394:       
1.187     brouard  8395:       /*   Design
                   8396:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   8397:        *  <          ncovcol=8                >
                   8398:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   8399:        *   k=  1    2      3       4     5       6      7        8
                   8400:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   8401:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  8402:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   8403:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  8404:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   8405:        *  Tage[++cptcovage]=k
                   8406:        *       if products, new covar are created after ncovcol with k1
                   8407:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   8408:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   8409:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   8410:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   8411:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   8412:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   8413:        *  <          ncovcol=8                >
                   8414:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   8415:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   8416:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   8417:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8418:        * p Tprod[1]@2={                         6, 5}
                   8419:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   8420:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   8421:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   8422:        *How to reorganize?
                   8423:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   8424:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8425:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   8426:        * Struct []
                   8427:        */
1.225     brouard  8428:       
1.187     brouard  8429:       /* This loop fills the array Tvar from the string 'model'.*/
                   8430:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   8431:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   8432:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   8433:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   8434:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   8435:       /*       k=1 Tvar[1]=2 (from V2) */
                   8436:       /*       k=5 Tvar[5] */
                   8437:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  8438:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  8439:       /*       } */
1.198     brouard  8440:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  8441:       /*
                   8442:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  8443:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   8444:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   8445:       }
1.187     brouard  8446:       cptcovage=0;
                   8447:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  8448:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  8449:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  8450:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   8451:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   8452:        /*scanf("%d",i);*/
                   8453:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   8454:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   8455:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   8456:            /* covar is not filled and then is empty */
                   8457:            cptcovprod--;
                   8458:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   8459:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   8460:            Typevar[k]=1;  /* 1 for age product */
                   8461:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   8462:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   8463:            /*printf("stre=%s ", stre);*/
                   8464:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   8465:            cptcovprod--;
                   8466:            cutl(stre,strb,strc,'V');
                   8467:            Tvar[k]=atoi(stre);
                   8468:            Typevar[k]=1;  /* 1 for age product */
                   8469:            cptcovage++;
                   8470:            Tage[cptcovage]=k;
                   8471:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   8472:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   8473:            cptcovn++;
                   8474:            cptcovprodnoage++;k1++;
                   8475:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   8476:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   8477:                                                because this model-covariate is a construction we invent a new column
                   8478:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   8479:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   8480:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   8481:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   8482:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   8483:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   8484:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   8485:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   8486:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   8487:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   8488:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   8489:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  8490:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  8491:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   8492:            for (i=1; i<=lastobs;i++){
                   8493:              /* Computes the new covariate which is a product of
                   8494:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   8495:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   8496:            }
                   8497:          } /* End age is not in the model */
                   8498:        } /* End if model includes a product */
                   8499:        else { /* no more sum */
                   8500:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   8501:          /*  scanf("%d",i);*/
                   8502:          cutl(strd,strc,strb,'V');
                   8503:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   8504:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   8505:          Tvar[k]=atoi(strd);
                   8506:          Typevar[k]=0;  /* 0 for simple covariates */
                   8507:        }
                   8508:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  8509:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  8510:                                  scanf("%d",i);*/
1.187     brouard  8511:       } /* end of loop + on total covariates */
                   8512:     } /* end if strlen(modelsave == 0) age*age might exist */
                   8513:   } /* end if strlen(model == 0) */
1.136     brouard  8514:   
                   8515:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   8516:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  8517:   
1.136     brouard  8518:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  8519:      printf("cptcovprod=%d ", cptcovprod);
                   8520:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   8521:      scanf("%d ",i);*/
                   8522: 
                   8523: 
1.230     brouard  8524: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   8525:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  8526: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   8527:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   8528:    k =           1    2   3     4       5       6      7      8        9
                   8529:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   8530:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  8531:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   8532:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   8533:          Tmodelind[combination of covar]=k;
1.225     brouard  8534: */  
                   8535: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  8536:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  8537:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  8538:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  8539:   printf("Model=%s\n\
                   8540: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8541: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8542: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8543:   fprintf(ficlog,"Model=%s\n\
                   8544: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8545: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8546: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  8547:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  8548:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   8549:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  8550:       Fixed[k]= 0;
                   8551:       Dummy[k]= 0;
1.225     brouard  8552:       ncoveff++;
1.232     brouard  8553:       ncovf++;
1.234     brouard  8554:       nsd++;
                   8555:       modell[k].maintype= FTYPE;
                   8556:       TvarsD[nsd]=Tvar[k];
                   8557:       TvarsDind[nsd]=k;
                   8558:       TvarF[ncovf]=Tvar[k];
                   8559:       TvarFind[ncovf]=k;
                   8560:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8561:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8562:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   8563:       Fixed[k]= 0;
                   8564:       Dummy[k]= 0;
                   8565:       ncoveff++;
                   8566:       ncovf++;
                   8567:       modell[k].maintype= FTYPE;
                   8568:       TvarF[ncovf]=Tvar[k];
                   8569:       TvarFind[ncovf]=k;
1.230     brouard  8570:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  8571:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  8572:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  8573:       Fixed[k]= 0;
                   8574:       Dummy[k]= 1;
1.230     brouard  8575:       nqfveff++;
1.234     brouard  8576:       modell[k].maintype= FTYPE;
                   8577:       modell[k].subtype= FQ;
                   8578:       nsq++;
                   8579:       TvarsQ[nsq]=Tvar[k];
                   8580:       TvarsQind[nsq]=k;
1.232     brouard  8581:       ncovf++;
1.234     brouard  8582:       TvarF[ncovf]=Tvar[k];
                   8583:       TvarFind[ncovf]=k;
1.231     brouard  8584:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  8585:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  8586:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  8587:       Fixed[k]= 1;
                   8588:       Dummy[k]= 0;
1.225     brouard  8589:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  8590:       modell[k].maintype= VTYPE;
                   8591:       modell[k].subtype= VD;
                   8592:       nsd++;
                   8593:       TvarsD[nsd]=Tvar[k];
                   8594:       TvarsDind[nsd]=k;
                   8595:       ncovv++; /* Only simple time varying variables */
                   8596:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8597:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8598:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   8599:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  8600:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   8601:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  8602:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  8603:       Fixed[k]= 1;
                   8604:       Dummy[k]= 1;
                   8605:       nqtveff++;
                   8606:       modell[k].maintype= VTYPE;
                   8607:       modell[k].subtype= VQ;
                   8608:       ncovv++; /* Only simple time varying variables */
                   8609:       nsq++;
                   8610:       TvarsQ[nsq]=Tvar[k];
                   8611:       TvarsQind[nsq]=k;
                   8612:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8613:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8614:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   8615:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  8616:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   8617:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   8618:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  8619:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  8620:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  8621:       ncova++;
                   8622:       TvarA[ncova]=Tvar[k];
                   8623:       TvarAind[ncova]=k;
1.231     brouard  8624:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  8625:        Fixed[k]= 2;
                   8626:        Dummy[k]= 2;
                   8627:        modell[k].maintype= ATYPE;
                   8628:        modell[k].subtype= APFD;
                   8629:        /* ncoveff++; */
1.227     brouard  8630:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  8631:        Fixed[k]= 2;
                   8632:        Dummy[k]= 3;
                   8633:        modell[k].maintype= ATYPE;
                   8634:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   8635:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  8636:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  8637:        Fixed[k]= 3;
                   8638:        Dummy[k]= 2;
                   8639:        modell[k].maintype= ATYPE;
                   8640:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   8641:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  8642:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  8643:        Fixed[k]= 3;
                   8644:        Dummy[k]= 3;
                   8645:        modell[k].maintype= ATYPE;
                   8646:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   8647:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  8648:       }
                   8649:     }else if (Typevar[k] == 2) {  /* product without age */
                   8650:       k1=Tposprod[k];
                   8651:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  8652:        if(Tvard[k1][2] <=ncovcol){
                   8653:          Fixed[k]= 1;
                   8654:          Dummy[k]= 0;
                   8655:          modell[k].maintype= FTYPE;
                   8656:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   8657:          ncovf++; /* Fixed variables without age */
                   8658:          TvarF[ncovf]=Tvar[k];
                   8659:          TvarFind[ncovf]=k;
                   8660:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8661:          Fixed[k]= 0;  /* or 2 ?*/
                   8662:          Dummy[k]= 1;
                   8663:          modell[k].maintype= FTYPE;
                   8664:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   8665:          ncovf++; /* Varying variables without age */
                   8666:          TvarF[ncovf]=Tvar[k];
                   8667:          TvarFind[ncovf]=k;
                   8668:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8669:          Fixed[k]= 1;
                   8670:          Dummy[k]= 0;
                   8671:          modell[k].maintype= VTYPE;
                   8672:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   8673:          ncovv++; /* Varying variables without age */
                   8674:          TvarV[ncovv]=Tvar[k];
                   8675:          TvarVind[ncovv]=k;
                   8676:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8677:          Fixed[k]= 1;
                   8678:          Dummy[k]= 1;
                   8679:          modell[k].maintype= VTYPE;
                   8680:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   8681:          ncovv++; /* Varying variables without age */
                   8682:          TvarV[ncovv]=Tvar[k];
                   8683:          TvarVind[ncovv]=k;
                   8684:        }
1.227     brouard  8685:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  8686:        if(Tvard[k1][2] <=ncovcol){
                   8687:          Fixed[k]= 0;  /* or 2 ?*/
                   8688:          Dummy[k]= 1;
                   8689:          modell[k].maintype= FTYPE;
                   8690:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   8691:          ncovf++; /* Fixed variables without age */
                   8692:          TvarF[ncovf]=Tvar[k];
                   8693:          TvarFind[ncovf]=k;
                   8694:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8695:          Fixed[k]= 1;
                   8696:          Dummy[k]= 1;
                   8697:          modell[k].maintype= VTYPE;
                   8698:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   8699:          ncovv++; /* Varying variables without age */
                   8700:          TvarV[ncovv]=Tvar[k];
                   8701:          TvarVind[ncovv]=k;
                   8702:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8703:          Fixed[k]= 1;
                   8704:          Dummy[k]= 1;
                   8705:          modell[k].maintype= VTYPE;
                   8706:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   8707:          ncovv++; /* Varying variables without age */
                   8708:          TvarV[ncovv]=Tvar[k];
                   8709:          TvarVind[ncovv]=k;
                   8710:          ncovv++; /* Varying variables without age */
                   8711:          TvarV[ncovv]=Tvar[k];
                   8712:          TvarVind[ncovv]=k;
                   8713:        }
1.227     brouard  8714:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  8715:        if(Tvard[k1][2] <=ncovcol){
                   8716:          Fixed[k]= 1;
                   8717:          Dummy[k]= 1;
                   8718:          modell[k].maintype= VTYPE;
                   8719:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   8720:          ncovv++; /* Varying variables without age */
                   8721:          TvarV[ncovv]=Tvar[k];
                   8722:          TvarVind[ncovv]=k;
                   8723:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8724:          Fixed[k]= 1;
                   8725:          Dummy[k]= 1;
                   8726:          modell[k].maintype= VTYPE;
                   8727:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   8728:          ncovv++; /* Varying variables without age */
                   8729:          TvarV[ncovv]=Tvar[k];
                   8730:          TvarVind[ncovv]=k;
                   8731:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8732:          Fixed[k]= 1;
                   8733:          Dummy[k]= 0;
                   8734:          modell[k].maintype= VTYPE;
                   8735:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   8736:          ncovv++; /* Varying variables without age */
                   8737:          TvarV[ncovv]=Tvar[k];
                   8738:          TvarVind[ncovv]=k;
                   8739:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8740:          Fixed[k]= 1;
                   8741:          Dummy[k]= 1;
                   8742:          modell[k].maintype= VTYPE;
                   8743:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   8744:          ncovv++; /* Varying variables without age */
                   8745:          TvarV[ncovv]=Tvar[k];
                   8746:          TvarVind[ncovv]=k;
                   8747:        }
1.227     brouard  8748:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  8749:        if(Tvard[k1][2] <=ncovcol){
                   8750:          Fixed[k]= 1;
                   8751:          Dummy[k]= 1;
                   8752:          modell[k].maintype= VTYPE;
                   8753:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   8754:          ncovv++; /* Varying variables without age */
                   8755:          TvarV[ncovv]=Tvar[k];
                   8756:          TvarVind[ncovv]=k;
                   8757:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8758:          Fixed[k]= 1;
                   8759:          Dummy[k]= 1;
                   8760:          modell[k].maintype= VTYPE;
                   8761:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   8762:          ncovv++; /* Varying variables without age */
                   8763:          TvarV[ncovv]=Tvar[k];
                   8764:          TvarVind[ncovv]=k;
                   8765:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8766:          Fixed[k]= 1;
                   8767:          Dummy[k]= 1;
                   8768:          modell[k].maintype= VTYPE;
                   8769:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   8770:          ncovv++; /* Varying variables without age */
                   8771:          TvarV[ncovv]=Tvar[k];
                   8772:          TvarVind[ncovv]=k;
                   8773:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8774:          Fixed[k]= 1;
                   8775:          Dummy[k]= 1;
                   8776:          modell[k].maintype= VTYPE;
                   8777:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   8778:          ncovv++; /* Varying variables without age */
                   8779:          TvarV[ncovv]=Tvar[k];
                   8780:          TvarVind[ncovv]=k;
                   8781:        }
1.227     brouard  8782:       }else{
1.240     brouard  8783:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   8784:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   8785:       } /*end k1*/
1.225     brouard  8786:     }else{
1.226     brouard  8787:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   8788:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  8789:     }
1.227     brouard  8790:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  8791:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  8792:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   8793:   }
                   8794:   /* Searching for doublons in the model */
                   8795:   for(k1=1; k1<= cptcovt;k1++){
                   8796:     for(k2=1; k2 <k1;k2++){
                   8797:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  8798:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   8799:          if(Tvar[k1]==Tvar[k2]){
                   8800:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   8801:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   8802:            return(1);
                   8803:          }
                   8804:        }else if (Typevar[k1] ==2){
                   8805:          k3=Tposprod[k1];
                   8806:          k4=Tposprod[k2];
                   8807:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   8808:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   8809:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   8810:            return(1);
                   8811:          }
                   8812:        }
1.227     brouard  8813:       }
                   8814:     }
1.225     brouard  8815:   }
                   8816:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   8817:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  8818:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   8819:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  8820:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  8821:   /*endread:*/
1.225     brouard  8822:   printf("Exiting decodemodel: ");
                   8823:   return (1);
1.136     brouard  8824: }
                   8825: 
1.169     brouard  8826: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.136     brouard  8827: {
                   8828:   int i, m;
1.218     brouard  8829:   int firstone=0;
                   8830:   
1.136     brouard  8831:   for (i=1; i<=imx; i++) {
                   8832:     for(m=2; (m<= maxwav); m++) {
                   8833:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   8834:        anint[m][i]=9999;
1.216     brouard  8835:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   8836:          s[m][i]=-1;
1.136     brouard  8837:       }
                   8838:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.169     brouard  8839:        *nberr = *nberr + 1;
1.218     brouard  8840:        if(firstone == 0){
                   8841:          firstone=1;
                   8842:        printf("Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\nOther similar cases in log file\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
                   8843:        }
                   8844:        fprintf(ficlog,"Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
1.136     brouard  8845:        s[m][i]=-1;
                   8846:       }
                   8847:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  8848:        (*nberr)++;
1.136     brouard  8849:        printf("Error! Month of death of individual %ld on line %d was unknown %2d, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,(int)moisdc[i]); 
                   8850:        fprintf(ficlog,"Error! Month of death of individual %ld on line %d was unknown %f, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,moisdc[i]); 
                   8851:        s[m][i]=-1; /* We prefer to skip it (and to skip it in version 0.8a1 too */
                   8852:       }
                   8853:     }
                   8854:   }
                   8855: 
                   8856:   for (i=1; i<=imx; i++)  {
                   8857:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   8858:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  8859:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  8860:        if (s[m][i] >= nlstate+1) {
1.169     brouard  8861:          if(agedc[i]>0){
                   8862:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  8863:              agev[m][i]=agedc[i];
1.214     brouard  8864:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  8865:            }else {
1.136     brouard  8866:              if ((int)andc[i]!=9999){
                   8867:                nbwarn++;
                   8868:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   8869:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   8870:                agev[m][i]=-1;
                   8871:              }
                   8872:            }
1.169     brouard  8873:          } /* agedc > 0 */
1.214     brouard  8874:        } /* end if */
1.136     brouard  8875:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   8876:                                 years but with the precision of a month */
                   8877:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   8878:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   8879:            agev[m][i]=1;
                   8880:          else if(agev[m][i] < *agemin){ 
                   8881:            *agemin=agev[m][i];
                   8882:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   8883:          }
                   8884:          else if(agev[m][i] >*agemax){
                   8885:            *agemax=agev[m][i];
1.156     brouard  8886:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  8887:          }
                   8888:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   8889:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  8890:        } /* en if 9*/
1.136     brouard  8891:        else { /* =9 */
1.214     brouard  8892:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  8893:          agev[m][i]=1;
                   8894:          s[m][i]=-1;
                   8895:        }
                   8896:       }
1.214     brouard  8897:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  8898:        agev[m][i]=1;
1.214     brouard  8899:       else{
                   8900:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   8901:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   8902:        agev[m][i]=0;
                   8903:       }
                   8904:     } /* End for lastpass */
                   8905:   }
1.136     brouard  8906:     
                   8907:   for (i=1; i<=imx; i++)  {
                   8908:     for(m=firstpass; (m<=lastpass); m++){
                   8909:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  8910:        (*nberr)++;
1.136     brouard  8911:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   8912:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   8913:        return 1;
                   8914:       }
                   8915:     }
                   8916:   }
                   8917: 
                   8918:   /*for (i=1; i<=imx; i++){
                   8919:   for (m=firstpass; (m<lastpass); m++){
                   8920:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   8921: }
                   8922: 
                   8923: }*/
                   8924: 
                   8925: 
1.139     brouard  8926:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   8927:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  8928: 
                   8929:   return (0);
1.164     brouard  8930:  /* endread:*/
1.136     brouard  8931:     printf("Exiting calandcheckages: ");
                   8932:     return (1);
                   8933: }
                   8934: 
1.172     brouard  8935: #if defined(_MSC_VER)
                   8936: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   8937: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   8938: //#include "stdafx.h"
                   8939: //#include <stdio.h>
                   8940: //#include <tchar.h>
                   8941: //#include <windows.h>
                   8942: //#include <iostream>
                   8943: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   8944: 
                   8945: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   8946: 
                   8947: BOOL IsWow64()
                   8948: {
                   8949:        BOOL bIsWow64 = FALSE;
                   8950: 
                   8951:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   8952:        //  (HANDLE, PBOOL);
                   8953: 
                   8954:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   8955: 
                   8956:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   8957:        const char funcName[] = "IsWow64Process";
                   8958:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   8959:                GetProcAddress(module, funcName);
                   8960: 
                   8961:        if (NULL != fnIsWow64Process)
                   8962:        {
                   8963:                if (!fnIsWow64Process(GetCurrentProcess(),
                   8964:                        &bIsWow64))
                   8965:                        //throw std::exception("Unknown error");
                   8966:                        printf("Unknown error\n");
                   8967:        }
                   8968:        return bIsWow64 != FALSE;
                   8969: }
                   8970: #endif
1.177     brouard  8971: 
1.191     brouard  8972: void syscompilerinfo(int logged)
1.167     brouard  8973:  {
                   8974:    /* #include "syscompilerinfo.h"*/
1.185     brouard  8975:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   8976:    /* /GS /W3 /Gy
                   8977:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   8978:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   8979:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  8980:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   8981:    */ 
                   8982:    /* 64 bits */
1.185     brouard  8983:    /*
                   8984:      /GS /W3 /Gy
                   8985:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   8986:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   8987:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   8988:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   8989:    /* Optimization are useless and O3 is slower than O2 */
                   8990:    /*
                   8991:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   8992:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   8993:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   8994:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   8995:    */
1.186     brouard  8996:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  8997:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   8998:       /PDB:"visual studio
                   8999:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   9000:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   9001:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   9002:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   9003:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   9004:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   9005:       uiAccess='false'"
                   9006:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   9007:       /NOLOGO /TLBID:1
                   9008:    */
1.177     brouard  9009: #if defined __INTEL_COMPILER
1.178     brouard  9010: #if defined(__GNUC__)
                   9011:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   9012: #endif
1.177     brouard  9013: #elif defined(__GNUC__) 
1.179     brouard  9014: #ifndef  __APPLE__
1.174     brouard  9015: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  9016: #endif
1.177     brouard  9017:    struct utsname sysInfo;
1.178     brouard  9018:    int cross = CROSS;
                   9019:    if (cross){
                   9020:           printf("Cross-");
1.191     brouard  9021:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  9022:    }
1.174     brouard  9023: #endif
                   9024: 
1.171     brouard  9025: #include <stdint.h>
1.178     brouard  9026: 
1.191     brouard  9027:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  9028: #if defined(__clang__)
1.191     brouard  9029:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  9030: #endif
                   9031: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  9032:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  9033: #endif
                   9034: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  9035:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  9036: #endif
                   9037: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  9038:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  9039: #endif
                   9040: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  9041:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  9042: #endif
                   9043: #if defined(_MSC_VER)
1.191     brouard  9044:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  9045: #endif
                   9046: #if defined(__PGI)
1.191     brouard  9047:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  9048: #endif
                   9049: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  9050:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  9051: #endif
1.191     brouard  9052:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  9053:    
1.167     brouard  9054: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   9055: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   9056:     // Windows (x64 and x86)
1.191     brouard  9057:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  9058: #elif __unix__ // all unices, not all compilers
                   9059:     // Unix
1.191     brouard  9060:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  9061: #elif __linux__
                   9062:     // linux
1.191     brouard  9063:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  9064: #elif __APPLE__
1.174     brouard  9065:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  9066:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  9067: #endif
                   9068: 
                   9069: /*  __MINGW32__          */
                   9070: /*  __CYGWIN__  */
                   9071: /* __MINGW64__  */
                   9072: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   9073: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   9074: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   9075: /* _WIN64  // Defined for applications for Win64. */
                   9076: /* _M_X64 // Defined for compilations that target x64 processors. */
                   9077: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  9078: 
1.167     brouard  9079: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  9080:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  9081: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  9082:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  9083: #else
1.191     brouard  9084:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  9085: #endif
                   9086: 
1.169     brouard  9087: #if defined(__GNUC__)
                   9088: # if defined(__GNUC_PATCHLEVEL__)
                   9089: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9090:                             + __GNUC_MINOR__ * 100 \
                   9091:                             + __GNUC_PATCHLEVEL__)
                   9092: # else
                   9093: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9094:                             + __GNUC_MINOR__ * 100)
                   9095: # endif
1.174     brouard  9096:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  9097:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  9098: 
                   9099:    if (uname(&sysInfo) != -1) {
                   9100:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  9101:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  9102:    }
                   9103:    else
                   9104:       perror("uname() error");
1.179     brouard  9105:    //#ifndef __INTEL_COMPILER 
                   9106: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  9107:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  9108:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  9109: #endif
1.169     brouard  9110: #endif
1.172     brouard  9111: 
                   9112:    //   void main()
                   9113:    //   {
1.169     brouard  9114: #if defined(_MSC_VER)
1.174     brouard  9115:    if (IsWow64()){
1.191     brouard  9116:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   9117:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  9118:    }
                   9119:    else{
1.191     brouard  9120:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   9121:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  9122:    }
1.172     brouard  9123:    //     printf("\nPress Enter to continue...");
                   9124:    //     getchar();
                   9125:    //   }
                   9126: 
1.169     brouard  9127: #endif
                   9128:    
1.167     brouard  9129: 
1.219     brouard  9130: }
1.136     brouard  9131: 
1.219     brouard  9132: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  9133:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  9134:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  9135:   /* double ftolpl = 1.e-10; */
1.180     brouard  9136:   double age, agebase, agelim;
1.203     brouard  9137:   double tot;
1.180     brouard  9138: 
1.202     brouard  9139:   strcpy(filerespl,"PL_");
                   9140:   strcat(filerespl,fileresu);
                   9141:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   9142:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9143:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9144:   }
1.227     brouard  9145:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   9146:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  9147:   pstamp(ficrespl);
1.203     brouard  9148:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  9149:   fprintf(ficrespl,"#Age ");
                   9150:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   9151:   fprintf(ficrespl,"\n");
1.180     brouard  9152:   
1.219     brouard  9153:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  9154: 
1.219     brouard  9155:   agebase=ageminpar;
                   9156:   agelim=agemaxpar;
1.180     brouard  9157: 
1.227     brouard  9158:   /* i1=pow(2,ncoveff); */
1.234     brouard  9159:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  9160:   if (cptcovn < 1){i1=1;}
1.180     brouard  9161: 
1.238     brouard  9162:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   9163:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9164:       if(TKresult[nres]!= k)
                   9165:        continue;
1.235     brouard  9166: 
1.238     brouard  9167:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9168:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   9169:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   9170:       /* k=k+1; */
                   9171:       /* to clean */
                   9172:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9173:       fprintf(ficrespl,"#******");
                   9174:       printf("#******");
                   9175:       fprintf(ficlog,"#******");
                   9176:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9177:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   9178:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9179:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9180:       }
                   9181:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9182:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9183:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9184:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9185:       }
                   9186:       fprintf(ficrespl,"******\n");
                   9187:       printf("******\n");
                   9188:       fprintf(ficlog,"******\n");
                   9189:       if(invalidvarcomb[k]){
                   9190:        printf("\nCombination (%d) ignored because no case \n",k); 
                   9191:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   9192:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   9193:        continue;
                   9194:       }
1.219     brouard  9195: 
1.238     brouard  9196:       fprintf(ficrespl,"#Age ");
                   9197:       for(j=1;j<=cptcoveff;j++) {
                   9198:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9199:       }
                   9200:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   9201:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  9202:     
1.238     brouard  9203:       for (age=agebase; age<=agelim; age++){
                   9204:        /* for (age=agebase; age<=agebase; age++){ */
                   9205:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   9206:        fprintf(ficrespl,"%.0f ",age );
                   9207:        for(j=1;j<=cptcoveff;j++)
                   9208:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9209:        tot=0.;
                   9210:        for(i=1; i<=nlstate;i++){
                   9211:          tot +=  prlim[i][i];
                   9212:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   9213:        }
                   9214:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   9215:       } /* Age */
                   9216:       /* was end of cptcod */
                   9217:     } /* cptcov */
                   9218:   } /* nres */
1.219     brouard  9219:   return 0;
1.180     brouard  9220: }
                   9221: 
1.218     brouard  9222: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   9223:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   9224:        
                   9225:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   9226:    * at any age between ageminpar and agemaxpar
                   9227:         */
1.235     brouard  9228:   int i, j, k, i1, nres=0 ;
1.217     brouard  9229:   /* double ftolpl = 1.e-10; */
                   9230:   double age, agebase, agelim;
                   9231:   double tot;
1.218     brouard  9232:   /* double ***mobaverage; */
                   9233:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  9234: 
                   9235:   strcpy(fileresplb,"PLB_");
                   9236:   strcat(fileresplb,fileresu);
                   9237:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   9238:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9239:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9240:   }
                   9241:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9242:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9243:   pstamp(ficresplb);
                   9244:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   9245:   fprintf(ficresplb,"#Age ");
                   9246:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   9247:   fprintf(ficresplb,"\n");
                   9248:   
1.218     brouard  9249:   
                   9250:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   9251:   
                   9252:   agebase=ageminpar;
                   9253:   agelim=agemaxpar;
                   9254:   
                   9255:   
1.227     brouard  9256:   i1=pow(2,cptcoveff);
1.218     brouard  9257:   if (cptcovn < 1){i1=1;}
1.227     brouard  9258:   
1.238     brouard  9259:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9260:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
                   9261:       if(TKresult[nres]!= k)
                   9262:        continue;
                   9263:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9264:       fprintf(ficresplb,"#******");
                   9265:       printf("#******");
                   9266:       fprintf(ficlog,"#******");
                   9267:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9268:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9269:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9270:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9271:       }
                   9272:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9273:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9274:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9275:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9276:       }
                   9277:       fprintf(ficresplb,"******\n");
                   9278:       printf("******\n");
                   9279:       fprintf(ficlog,"******\n");
                   9280:       if(invalidvarcomb[k]){
                   9281:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   9282:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   9283:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   9284:        continue;
                   9285:       }
1.218     brouard  9286:     
1.238     brouard  9287:       fprintf(ficresplb,"#Age ");
                   9288:       for(j=1;j<=cptcoveff;j++) {
                   9289:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9290:       }
                   9291:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   9292:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  9293:     
                   9294:     
1.238     brouard  9295:       for (age=agebase; age<=agelim; age++){
                   9296:        /* for (age=agebase; age<=agebase; age++){ */
                   9297:        if(mobilavproj > 0){
                   9298:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   9299:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9300:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  9301:        }else if (mobilavproj == 0){
                   9302:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9303:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9304:          exit(1);
                   9305:        }else{
                   9306:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9307:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.238     brouard  9308:        }
                   9309:        fprintf(ficresplb,"%.0f ",age );
                   9310:        for(j=1;j<=cptcoveff;j++)
                   9311:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9312:        tot=0.;
                   9313:        for(i=1; i<=nlstate;i++){
                   9314:          tot +=  bprlim[i][i];
                   9315:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   9316:        }
                   9317:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   9318:       } /* Age */
                   9319:       /* was end of cptcod */
                   9320:     } /* end of any combination */
                   9321:   } /* end of nres */  
1.218     brouard  9322:   /* hBijx(p, bage, fage); */
                   9323:   /* fclose(ficrespijb); */
                   9324:   
                   9325:   return 0;
1.217     brouard  9326: }
1.218     brouard  9327:  
1.180     brouard  9328: int hPijx(double *p, int bage, int fage){
                   9329:     /*------------- h Pij x at various ages ------------*/
                   9330: 
                   9331:   int stepsize;
                   9332:   int agelim;
                   9333:   int hstepm;
                   9334:   int nhstepm;
1.235     brouard  9335:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  9336: 
                   9337:   double agedeb;
                   9338:   double ***p3mat;
                   9339: 
1.201     brouard  9340:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  9341:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   9342:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9343:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9344:     }
                   9345:     printf("Computing pij: result on file '%s' \n", filerespij);
                   9346:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   9347:   
                   9348:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9349:     /*if (stepm<=24) stepsize=2;*/
                   9350: 
                   9351:     agelim=AGESUP;
                   9352:     hstepm=stepsize*YEARM; /* Every year of age */
                   9353:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  9354:                
1.180     brouard  9355:     /* hstepm=1;   aff par mois*/
                   9356:     pstamp(ficrespij);
                   9357:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  9358:     i1= pow(2,cptcoveff);
1.218     brouard  9359:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9360:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9361:                /*      k=k+1;  */
1.235     brouard  9362:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9363:     for(k=1; k<=i1;k++){
                   9364:       if(TKresult[nres]!= k)
                   9365:        continue;
1.183     brouard  9366:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  9367:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  9368:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  9369:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9370:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9371:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9372:       }
1.183     brouard  9373:       fprintf(ficrespij,"******\n");
                   9374:       
                   9375:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   9376:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   9377:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   9378:        
                   9379:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  9380:        
1.183     brouard  9381:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9382:        oldm=oldms;savm=savms;
1.235     brouard  9383:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  9384:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   9385:        for(i=1; i<=nlstate;i++)
                   9386:          for(j=1; j<=nlstate+ndeath;j++)
                   9387:            fprintf(ficrespij," %1d-%1d",i,j);
                   9388:        fprintf(ficrespij,"\n");
                   9389:        for (h=0; h<=nhstepm; h++){
                   9390:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9391:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  9392:          for(i=1; i<=nlstate;i++)
                   9393:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  9394:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  9395:          fprintf(ficrespij,"\n");
                   9396:        }
1.183     brouard  9397:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9398:        fprintf(ficrespij,"\n");
                   9399:       }
1.180     brouard  9400:       /*}*/
                   9401:     }
1.218     brouard  9402:     return 0;
1.180     brouard  9403: }
1.218     brouard  9404:  
                   9405:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  9406:     /*------------- h Bij x at various ages ------------*/
                   9407: 
                   9408:   int stepsize;
1.218     brouard  9409:   /* int agelim; */
                   9410:        int ageminl;
1.217     brouard  9411:   int hstepm;
                   9412:   int nhstepm;
1.238     brouard  9413:   int h, i, i1, j, k, nres;
1.218     brouard  9414:        
1.217     brouard  9415:   double agedeb;
                   9416:   double ***p3mat;
1.218     brouard  9417:        
                   9418:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   9419:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   9420:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9421:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9422:   }
                   9423:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   9424:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   9425:   
                   9426:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9427:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  9428:   
1.218     brouard  9429:   /* agelim=AGESUP; */
                   9430:   ageminl=30;
                   9431:   hstepm=stepsize*YEARM; /* Every year of age */
                   9432:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   9433:   
                   9434:   /* hstepm=1;   aff par mois*/
                   9435:   pstamp(ficrespijb);
                   9436:   fprintf(ficrespijb,"#****** h Pij x Back Probability to be in state i at age x-h being in j at x ");
1.227     brouard  9437:   i1= pow(2,cptcoveff);
1.218     brouard  9438:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9439:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9440:   /*   k=k+1;  */
1.238     brouard  9441:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9442:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
                   9443:       if(TKresult[nres]!= k)
                   9444:        continue;
                   9445:       fprintf(ficrespijb,"\n#****** ");
                   9446:       for(j=1;j<=cptcoveff;j++)
                   9447:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9448:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9449:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9450:       }
                   9451:       fprintf(ficrespijb,"******\n");
                   9452:       if(invalidvarcomb[k]){
                   9453:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   9454:        continue;
                   9455:       }
                   9456:       
                   9457:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   9458:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   9459:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   9460:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   9461:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   9462:        
                   9463:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   9464:        
                   9465:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9466:        /* oldm=oldms;savm=savms; */
                   9467:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9468:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k);
                   9469:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
                   9470:        fprintf(ficrespijb,"# Cov Agex agex-h hpijx with i,j=");
1.217     brouard  9471:        for(i=1; i<=nlstate;i++)
                   9472:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  9473:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  9474:        fprintf(ficrespijb,"\n");
1.238     brouard  9475:        for (h=0; h<=nhstepm; h++){
                   9476:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9477:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   9478:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   9479:          for(i=1; i<=nlstate;i++)
                   9480:            for(j=1; j<=nlstate+ndeath;j++)
                   9481:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   9482:          fprintf(ficrespijb,"\n");
                   9483:        }
                   9484:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9485:        fprintf(ficrespijb,"\n");
                   9486:       } /* end age deb */
                   9487:     } /* end combination */
                   9488:   } /* end nres */
1.218     brouard  9489:   return 0;
                   9490:  } /*  hBijx */
1.217     brouard  9491: 
1.180     brouard  9492: 
1.136     brouard  9493: /***********************************************/
                   9494: /**************** Main Program *****************/
                   9495: /***********************************************/
                   9496: 
                   9497: int main(int argc, char *argv[])
                   9498: {
                   9499: #ifdef GSL
                   9500:   const gsl_multimin_fminimizer_type *T;
                   9501:   size_t iteri = 0, it;
                   9502:   int rval = GSL_CONTINUE;
                   9503:   int status = GSL_SUCCESS;
                   9504:   double ssval;
                   9505: #endif
                   9506:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  9507:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  9508:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  9509:   int jj, ll, li, lj, lk;
1.136     brouard  9510:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  9511:   int num_filled;
1.136     brouard  9512:   int itimes;
                   9513:   int NDIM=2;
                   9514:   int vpopbased=0;
1.235     brouard  9515:   int nres=0;
1.136     brouard  9516: 
1.164     brouard  9517:   char ca[32], cb[32];
1.136     brouard  9518:   /*  FILE *fichtm; *//* Html File */
                   9519:   /* FILE *ficgp;*/ /*Gnuplot File */
                   9520:   struct stat info;
1.191     brouard  9521:   double agedeb=0.;
1.194     brouard  9522: 
                   9523:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  9524:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  9525: 
1.165     brouard  9526:   double fret;
1.191     brouard  9527:   double dum=0.; /* Dummy variable */
1.136     brouard  9528:   double ***p3mat;
1.218     brouard  9529:   /* double ***mobaverage; */
1.164     brouard  9530: 
                   9531:   char line[MAXLINE];
1.197     brouard  9532:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   9533: 
1.234     brouard  9534:   char  modeltemp[MAXLINE];
1.230     brouard  9535:   char resultline[MAXLINE];
                   9536:   
1.136     brouard  9537:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  9538:   char *tok, *val; /* pathtot */
1.136     brouard  9539:   int firstobs=1, lastobs=10;
1.195     brouard  9540:   int c,  h , cpt, c2;
1.191     brouard  9541:   int jl=0;
                   9542:   int i1, j1, jk, stepsize=0;
1.194     brouard  9543:   int count=0;
                   9544: 
1.164     brouard  9545:   int *tab; 
1.136     brouard  9546:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  9547:   int backcast=0;
1.136     brouard  9548:   int mobilav=0,popforecast=0;
1.191     brouard  9549:   int hstepm=0, nhstepm=0;
1.136     brouard  9550:   int agemortsup;
                   9551:   float  sumlpop=0.;
                   9552:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   9553:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   9554: 
1.191     brouard  9555:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  9556:   double ftolpl=FTOL;
                   9557:   double **prlim;
1.217     brouard  9558:   double **bprlim;
1.136     brouard  9559:   double ***param; /* Matrix of parameters */
                   9560:   double  *p;
                   9561:   double **matcov; /* Matrix of covariance */
1.203     brouard  9562:   double **hess; /* Hessian matrix */
1.136     brouard  9563:   double ***delti3; /* Scale */
                   9564:   double *delti; /* Scale */
                   9565:   double ***eij, ***vareij;
                   9566:   double **varpl; /* Variances of prevalence limits by age */
                   9567:   double *epj, vepp;
1.164     brouard  9568: 
1.136     brouard  9569:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  9570:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   9571: 
1.136     brouard  9572:   double **ximort;
1.145     brouard  9573:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  9574:   int *dcwave;
                   9575: 
1.164     brouard  9576:   char z[1]="c";
1.136     brouard  9577: 
                   9578:   /*char  *strt;*/
                   9579:   char strtend[80];
1.126     brouard  9580: 
1.164     brouard  9581: 
1.126     brouard  9582: /*   setlocale (LC_ALL, ""); */
                   9583: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   9584: /*   textdomain (PACKAGE); */
                   9585: /*   setlocale (LC_CTYPE, ""); */
                   9586: /*   setlocale (LC_MESSAGES, ""); */
                   9587: 
                   9588:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  9589:   rstart_time = time(NULL);  
                   9590:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   9591:   start_time = *localtime(&rstart_time);
1.126     brouard  9592:   curr_time=start_time;
1.157     brouard  9593:   /*tml = *localtime(&start_time.tm_sec);*/
                   9594:   /* strcpy(strstart,asctime(&tml)); */
                   9595:   strcpy(strstart,asctime(&start_time));
1.126     brouard  9596: 
                   9597: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  9598: /*  tp.tm_sec = tp.tm_sec +86400; */
                   9599: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  9600: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   9601: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   9602: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  9603: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  9604: /*   strt=asctime(&tmg); */
                   9605: /*   printf("Time(after) =%s",strstart);  */
                   9606: /*  (void) time (&time_value);
                   9607: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   9608: *  tm = *localtime(&time_value);
                   9609: *  strstart=asctime(&tm);
                   9610: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   9611: */
                   9612: 
                   9613:   nberr=0; /* Number of errors and warnings */
                   9614:   nbwarn=0;
1.184     brouard  9615: #ifdef WIN32
                   9616:   _getcwd(pathcd, size);
                   9617: #else
1.126     brouard  9618:   getcwd(pathcd, size);
1.184     brouard  9619: #endif
1.191     brouard  9620:   syscompilerinfo(0);
1.196     brouard  9621:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  9622:   if(argc <=1){
                   9623:     printf("\nEnter the parameter file name: ");
1.205     brouard  9624:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   9625:       printf("ERROR Empty parameter file name\n");
                   9626:       goto end;
                   9627:     }
1.126     brouard  9628:     i=strlen(pathr);
                   9629:     if(pathr[i-1]=='\n')
                   9630:       pathr[i-1]='\0';
1.156     brouard  9631:     i=strlen(pathr);
1.205     brouard  9632:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  9633:       pathr[i-1]='\0';
1.205     brouard  9634:     }
                   9635:     i=strlen(pathr);
                   9636:     if( i==0 ){
                   9637:       printf("ERROR Empty parameter file name\n");
                   9638:       goto end;
                   9639:     }
                   9640:     for (tok = pathr; tok != NULL; ){
1.126     brouard  9641:       printf("Pathr |%s|\n",pathr);
                   9642:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   9643:       printf("val= |%s| pathr=%s\n",val,pathr);
                   9644:       strcpy (pathtot, val);
                   9645:       if(pathr[0] == '\0') break; /* Dirty */
                   9646:     }
                   9647:   }
                   9648:   else{
                   9649:     strcpy(pathtot,argv[1]);
                   9650:   }
                   9651:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   9652:   /*cygwin_split_path(pathtot,path,optionfile);
                   9653:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   9654:   /* cutv(path,optionfile,pathtot,'\\');*/
                   9655: 
                   9656:   /* Split argv[0], imach program to get pathimach */
                   9657:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   9658:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9659:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9660:  /*   strcpy(pathimach,argv[0]); */
                   9661:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   9662:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   9663:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  9664: #ifdef WIN32
                   9665:   _chdir(path); /* Can be a relative path */
                   9666:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   9667: #else
1.126     brouard  9668:   chdir(path); /* Can be a relative path */
1.184     brouard  9669:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   9670: #endif
                   9671:   printf("Current directory %s!\n",pathcd);
1.126     brouard  9672:   strcpy(command,"mkdir ");
                   9673:   strcat(command,optionfilefiname);
                   9674:   if((outcmd=system(command)) != 0){
1.169     brouard  9675:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  9676:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   9677:     /* fclose(ficlog); */
                   9678: /*     exit(1); */
                   9679:   }
                   9680: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   9681: /*     perror("mkdir"); */
                   9682: /*   } */
                   9683: 
                   9684:   /*-------- arguments in the command line --------*/
                   9685: 
1.186     brouard  9686:   /* Main Log file */
1.126     brouard  9687:   strcat(filelog, optionfilefiname);
                   9688:   strcat(filelog,".log");    /* */
                   9689:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   9690:     printf("Problem with logfile %s\n",filelog);
                   9691:     goto end;
                   9692:   }
                   9693:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  9694:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  9695:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   9696:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   9697:  path=%s \n\
                   9698:  optionfile=%s\n\
                   9699:  optionfilext=%s\n\
1.156     brouard  9700:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  9701: 
1.197     brouard  9702:   syscompilerinfo(1);
1.167     brouard  9703: 
1.126     brouard  9704:   printf("Local time (at start):%s",strstart);
                   9705:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   9706:   fflush(ficlog);
                   9707: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  9708: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  9709: 
                   9710:   /* */
                   9711:   strcpy(fileres,"r");
                   9712:   strcat(fileres, optionfilefiname);
1.201     brouard  9713:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  9714:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  9715:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  9716: 
1.186     brouard  9717:   /* Main ---------arguments file --------*/
1.126     brouard  9718: 
                   9719:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  9720:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   9721:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  9722:     fflush(ficlog);
1.149     brouard  9723:     /* goto end; */
                   9724:     exit(70); 
1.126     brouard  9725:   }
                   9726: 
                   9727: 
                   9728: 
                   9729:   strcpy(filereso,"o");
1.201     brouard  9730:   strcat(filereso,fileresu);
1.126     brouard  9731:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   9732:     printf("Problem with Output resultfile: %s\n", filereso);
                   9733:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   9734:     fflush(ficlog);
                   9735:     goto end;
                   9736:   }
                   9737: 
                   9738:   /* Reads comments: lines beginning with '#' */
                   9739:   numlinepar=0;
1.197     brouard  9740: 
                   9741:     /* First parameter line */
                   9742:   while(fgets(line, MAXLINE, ficpar)) {
                   9743:     /* If line starts with a # it is a comment */
                   9744:     if (line[0] == '#') {
                   9745:       numlinepar++;
                   9746:       fputs(line,stdout);
                   9747:       fputs(line,ficparo);
                   9748:       fputs(line,ficlog);
                   9749:       continue;
                   9750:     }else
                   9751:       break;
                   9752:   }
                   9753:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   9754:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   9755:     if (num_filled != 5) {
                   9756:       printf("Should be 5 parameters\n");
                   9757:     }
1.126     brouard  9758:     numlinepar++;
1.197     brouard  9759:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   9760:   }
                   9761:   /* Second parameter line */
                   9762:   while(fgets(line, MAXLINE, ficpar)) {
                   9763:     /* If line starts with a # it is a comment */
                   9764:     if (line[0] == '#') {
                   9765:       numlinepar++;
                   9766:       fputs(line,stdout);
                   9767:       fputs(line,ficparo);
                   9768:       fputs(line,ficlog);
                   9769:       continue;
                   9770:     }else
                   9771:       break;
                   9772:   }
1.223     brouard  9773:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   9774:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   9775:     if (num_filled != 11) {
                   9776:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  9777:       printf("but line=%s\n",line);
1.197     brouard  9778:     }
1.223     brouard  9779:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  9780:   }
1.203     brouard  9781:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  9782:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  9783:   /* Third parameter line */
                   9784:   while(fgets(line, MAXLINE, ficpar)) {
                   9785:     /* If line starts with a # it is a comment */
                   9786:     if (line[0] == '#') {
                   9787:       numlinepar++;
                   9788:       fputs(line,stdout);
                   9789:       fputs(line,ficparo);
                   9790:       fputs(line,ficlog);
                   9791:       continue;
                   9792:     }else
                   9793:       break;
                   9794:   }
1.201     brouard  9795:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
                   9796:     if (num_filled == 0)
                   9797:             model[0]='\0';
                   9798:     else if (num_filled != 1){
1.197     brouard  9799:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   9800:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   9801:       model[0]='\0';
                   9802:       goto end;
                   9803:     }
                   9804:     else{
                   9805:       if (model[0]=='+'){
                   9806:        for(i=1; i<=strlen(model);i++)
                   9807:          modeltemp[i-1]=model[i];
1.201     brouard  9808:        strcpy(model,modeltemp); 
1.197     brouard  9809:       }
                   9810:     }
1.199     brouard  9811:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  9812:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  9813:   }
                   9814:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   9815:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   9816:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  9817:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   9818:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  9819:   fflush(ficlog);
1.190     brouard  9820:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   9821:   if(model[0]=='#'){
1.187     brouard  9822:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   9823:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   9824:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   9825:     if(mle != -1){
                   9826:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   9827:       exit(1);
                   9828:     }
                   9829:   }
1.126     brouard  9830:   while((c=getc(ficpar))=='#' && c!= EOF){
                   9831:     ungetc(c,ficpar);
                   9832:     fgets(line, MAXLINE, ficpar);
                   9833:     numlinepar++;
1.195     brouard  9834:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   9835:       z[0]=line[1];
                   9836:     }
                   9837:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  9838:     fputs(line, stdout);
                   9839:     //puts(line);
1.126     brouard  9840:     fputs(line,ficparo);
                   9841:     fputs(line,ficlog);
                   9842:   }
                   9843:   ungetc(c,ficpar);
                   9844: 
                   9845:    
1.145     brouard  9846:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.225     brouard  9847:   coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
1.233     brouard  9848:   cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.225     brouard  9849:   cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
1.136     brouard  9850:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   9851:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   9852:      v1+v2*age+v2*v3 makes cptcovn = 3
                   9853:   */
                   9854:   if (strlen(model)>1) 
1.187     brouard  9855:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  9856:   else
1.187     brouard  9857:     ncovmodel=2; /* Constant and age */
1.133     brouard  9858:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   9859:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  9860:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   9861:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   9862:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   9863:     fflush(stdout);
                   9864:     fclose (ficlog);
                   9865:     goto end;
                   9866:   }
1.126     brouard  9867:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   9868:   delti=delti3[1][1];
                   9869:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   9870:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
                   9871:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  9872:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   9873:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  9874:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   9875:     fclose (ficparo);
                   9876:     fclose (ficlog);
                   9877:     goto end;
                   9878:     exit(0);
1.220     brouard  9879:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  9880:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  9881:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   9882:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  9883:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   9884:     matcov=matrix(1,npar,1,npar);
1.203     brouard  9885:     hess=matrix(1,npar,1,npar);
1.220     brouard  9886:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  9887:     /* Read guessed parameters */
1.126     brouard  9888:     /* Reads comments: lines beginning with '#' */
                   9889:     while((c=getc(ficpar))=='#' && c!= EOF){
                   9890:       ungetc(c,ficpar);
                   9891:       fgets(line, MAXLINE, ficpar);
                   9892:       numlinepar++;
1.141     brouard  9893:       fputs(line,stdout);
1.126     brouard  9894:       fputs(line,ficparo);
                   9895:       fputs(line,ficlog);
                   9896:     }
                   9897:     ungetc(c,ficpar);
                   9898:     
                   9899:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   9900:     for(i=1; i <=nlstate; i++){
1.234     brouard  9901:       j=0;
1.126     brouard  9902:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  9903:        if(jj==i) continue;
                   9904:        j++;
                   9905:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   9906:        if ((i1 != i) || (j1 != jj)){
                   9907:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  9908: It might be a problem of design; if ncovcol and the model are correct\n \
                   9909: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  9910:          exit(1);
                   9911:        }
                   9912:        fprintf(ficparo,"%1d%1d",i1,j1);
                   9913:        if(mle==1)
                   9914:          printf("%1d%1d",i,jj);
                   9915:        fprintf(ficlog,"%1d%1d",i,jj);
                   9916:        for(k=1; k<=ncovmodel;k++){
                   9917:          fscanf(ficpar," %lf",&param[i][j][k]);
                   9918:          if(mle==1){
                   9919:            printf(" %lf",param[i][j][k]);
                   9920:            fprintf(ficlog," %lf",param[i][j][k]);
                   9921:          }
                   9922:          else
                   9923:            fprintf(ficlog," %lf",param[i][j][k]);
                   9924:          fprintf(ficparo," %lf",param[i][j][k]);
                   9925:        }
                   9926:        fscanf(ficpar,"\n");
                   9927:        numlinepar++;
                   9928:        if(mle==1)
                   9929:          printf("\n");
                   9930:        fprintf(ficlog,"\n");
                   9931:        fprintf(ficparo,"\n");
1.126     brouard  9932:       }
                   9933:     }  
                   9934:     fflush(ficlog);
1.234     brouard  9935:     
1.145     brouard  9936:     /* Reads scales values */
1.126     brouard  9937:     p=param[1][1];
                   9938:     
                   9939:     /* Reads comments: lines beginning with '#' */
                   9940:     while((c=getc(ficpar))=='#' && c!= EOF){
                   9941:       ungetc(c,ficpar);
                   9942:       fgets(line, MAXLINE, ficpar);
                   9943:       numlinepar++;
1.141     brouard  9944:       fputs(line,stdout);
1.126     brouard  9945:       fputs(line,ficparo);
                   9946:       fputs(line,ficlog);
                   9947:     }
                   9948:     ungetc(c,ficpar);
                   9949: 
                   9950:     for(i=1; i <=nlstate; i++){
                   9951:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  9952:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   9953:        if ( (i1-i) * (j1-j) != 0){
                   9954:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   9955:          exit(1);
                   9956:        }
                   9957:        printf("%1d%1d",i,j);
                   9958:        fprintf(ficparo,"%1d%1d",i1,j1);
                   9959:        fprintf(ficlog,"%1d%1d",i1,j1);
                   9960:        for(k=1; k<=ncovmodel;k++){
                   9961:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   9962:          printf(" %le",delti3[i][j][k]);
                   9963:          fprintf(ficparo," %le",delti3[i][j][k]);
                   9964:          fprintf(ficlog," %le",delti3[i][j][k]);
                   9965:        }
                   9966:        fscanf(ficpar,"\n");
                   9967:        numlinepar++;
                   9968:        printf("\n");
                   9969:        fprintf(ficparo,"\n");
                   9970:        fprintf(ficlog,"\n");
1.126     brouard  9971:       }
                   9972:     }
                   9973:     fflush(ficlog);
1.234     brouard  9974:     
1.145     brouard  9975:     /* Reads covariance matrix */
1.126     brouard  9976:     delti=delti3[1][1];
1.220     brouard  9977:                
                   9978:                
1.126     brouard  9979:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  9980:                
1.126     brouard  9981:     /* Reads comments: lines beginning with '#' */
                   9982:     while((c=getc(ficpar))=='#' && c!= EOF){
                   9983:       ungetc(c,ficpar);
                   9984:       fgets(line, MAXLINE, ficpar);
                   9985:       numlinepar++;
1.141     brouard  9986:       fputs(line,stdout);
1.126     brouard  9987:       fputs(line,ficparo);
                   9988:       fputs(line,ficlog);
                   9989:     }
                   9990:     ungetc(c,ficpar);
1.220     brouard  9991:                
1.126     brouard  9992:     matcov=matrix(1,npar,1,npar);
1.203     brouard  9993:     hess=matrix(1,npar,1,npar);
1.131     brouard  9994:     for(i=1; i <=npar; i++)
                   9995:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  9996:                
1.194     brouard  9997:     /* Scans npar lines */
1.126     brouard  9998:     for(i=1; i <=npar; i++){
1.226     brouard  9999:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  10000:       if(count != 3){
1.226     brouard  10001:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10002: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10003: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10004:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10005: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10006: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10007:        exit(1);
1.220     brouard  10008:       }else{
1.226     brouard  10009:        if(mle==1)
                   10010:          printf("%1d%1d%d",i1,j1,jk);
                   10011:       }
                   10012:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   10013:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  10014:       for(j=1; j <=i; j++){
1.226     brouard  10015:        fscanf(ficpar," %le",&matcov[i][j]);
                   10016:        if(mle==1){
                   10017:          printf(" %.5le",matcov[i][j]);
                   10018:        }
                   10019:        fprintf(ficlog," %.5le",matcov[i][j]);
                   10020:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  10021:       }
                   10022:       fscanf(ficpar,"\n");
                   10023:       numlinepar++;
                   10024:       if(mle==1)
1.220     brouard  10025:                                printf("\n");
1.126     brouard  10026:       fprintf(ficlog,"\n");
                   10027:       fprintf(ficparo,"\n");
                   10028:     }
1.194     brouard  10029:     /* End of read covariance matrix npar lines */
1.126     brouard  10030:     for(i=1; i <=npar; i++)
                   10031:       for(j=i+1;j<=npar;j++)
1.226     brouard  10032:        matcov[i][j]=matcov[j][i];
1.126     brouard  10033:     
                   10034:     if(mle==1)
                   10035:       printf("\n");
                   10036:     fprintf(ficlog,"\n");
                   10037:     
                   10038:     fflush(ficlog);
                   10039:     
                   10040:     /*-------- Rewriting parameter file ----------*/
                   10041:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   10042:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   10043:     strcat(rfileres,".");    /* */
                   10044:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10045:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  10046:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10047:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  10048:     }
                   10049:     fprintf(ficres,"#%s\n",version);
                   10050:   }    /* End of mle != -3 */
1.218     brouard  10051:   
1.186     brouard  10052:   /*  Main data
                   10053:    */
1.126     brouard  10054:   n= lastobs;
                   10055:   num=lvector(1,n);
                   10056:   moisnais=vector(1,n);
                   10057:   annais=vector(1,n);
                   10058:   moisdc=vector(1,n);
                   10059:   andc=vector(1,n);
1.220     brouard  10060:   weight=vector(1,n);
1.126     brouard  10061:   agedc=vector(1,n);
                   10062:   cod=ivector(1,n);
1.220     brouard  10063:   for(i=1;i<=n;i++){
1.234     brouard  10064:     num[i]=0;
                   10065:     moisnais[i]=0;
                   10066:     annais[i]=0;
                   10067:     moisdc[i]=0;
                   10068:     andc[i]=0;
                   10069:     agedc[i]=0;
                   10070:     cod[i]=0;
                   10071:     weight[i]=1.0; /* Equal weights, 1 by default */
                   10072:   }
1.126     brouard  10073:   mint=matrix(1,maxwav,1,n);
                   10074:   anint=matrix(1,maxwav,1,n);
1.131     brouard  10075:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  10076:   tab=ivector(1,NCOVMAX);
1.144     brouard  10077:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  10078:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  10079: 
1.136     brouard  10080:   /* Reads data from file datafile */
                   10081:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   10082:     goto end;
                   10083: 
                   10084:   /* Calculation of the number of parameters from char model */
1.234     brouard  10085:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  10086:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   10087:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   10088:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   10089:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  10090:   */
                   10091:   
                   10092:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   10093:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   10094:   TvarsD=ivector(1,NCOVMAX); /*  */
                   10095:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   10096:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  10097:   TvarF=ivector(1,NCOVMAX); /*  */
                   10098:   TvarFind=ivector(1,NCOVMAX); /*  */
                   10099:   TvarV=ivector(1,NCOVMAX); /*  */
                   10100:   TvarVind=ivector(1,NCOVMAX); /*  */
                   10101:   TvarA=ivector(1,NCOVMAX); /*  */
                   10102:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  10103:   TvarFD=ivector(1,NCOVMAX); /*  */
                   10104:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   10105:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   10106:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   10107:   TvarVD=ivector(1,NCOVMAX); /*  */
                   10108:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   10109:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   10110:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   10111: 
1.230     brouard  10112:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  10113:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  10114:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   10115:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   10116:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  10117:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   10118:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   10119:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   10120:   */
                   10121:   /* For model-covariate k tells which data-covariate to use but
                   10122:     because this model-covariate is a construction we invent a new column
                   10123:     ncovcol + k1
                   10124:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   10125:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  10126:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   10127:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  10128:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   10129:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  10130:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  10131:   */
1.145     brouard  10132:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   10133:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  10134:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   10135:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  10136:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  10137:                         4 covariates (3 plus signs)
                   10138:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   10139:                      */  
1.230     brouard  10140:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  10141:                                * individual dummy, fixed or varying:
                   10142:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   10143:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  10144:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   10145:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   10146:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   10147:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   10148:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  10149:                                * individual quantitative, fixed or varying:
                   10150:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   10151:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   10152:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  10153: /* Main decodemodel */
                   10154: 
1.187     brouard  10155: 
1.223     brouard  10156:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  10157:     goto end;
                   10158: 
1.137     brouard  10159:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   10160:     nbwarn++;
                   10161:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10162:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10163:   }
1.136     brouard  10164:     /*  if(mle==1){*/
1.137     brouard  10165:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   10166:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  10167:   }
                   10168: 
                   10169:     /*-calculation of age at interview from date of interview and age at death -*/
                   10170:   agev=matrix(1,maxwav,1,imx);
                   10171: 
                   10172:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   10173:     goto end;
                   10174: 
1.126     brouard  10175: 
1.136     brouard  10176:   agegomp=(int)agemin;
                   10177:   free_vector(moisnais,1,n);
                   10178:   free_vector(annais,1,n);
1.126     brouard  10179:   /* free_matrix(mint,1,maxwav,1,n);
                   10180:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  10181:   /* free_vector(moisdc,1,n); */
                   10182:   /* free_vector(andc,1,n); */
1.145     brouard  10183:   /* */
                   10184:   
1.126     brouard  10185:   wav=ivector(1,imx);
1.214     brouard  10186:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10187:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10188:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10189:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   10190:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   10191:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  10192:    
                   10193:   /* Concatenates waves */
1.214     brouard  10194:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   10195:      Death is a valid wave (if date is known).
                   10196:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   10197:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   10198:      and mw[mi+1][i]. dh depends on stepm.
                   10199:   */
                   10200: 
1.126     brouard  10201:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.145     brouard  10202:   /* */
                   10203:  
1.215     brouard  10204:   free_vector(moisdc,1,n);
                   10205:   free_vector(andc,1,n);
                   10206: 
1.126     brouard  10207:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   10208:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   10209:   ncodemax[1]=1;
1.145     brouard  10210:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  10211:   cptcoveff=0;
1.220     brouard  10212:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   10213:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  10214:   }
                   10215:   
                   10216:   ncovcombmax=pow(2,cptcoveff);
                   10217:   invalidvarcomb=ivector(1, ncovcombmax); 
                   10218:   for(i=1;i<ncovcombmax;i++)
                   10219:     invalidvarcomb[i]=0;
                   10220:   
1.211     brouard  10221:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  10222:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  10223:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  10224:   
1.200     brouard  10225:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  10226:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  10227:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  10228:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   10229:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   10230:    * (currently 0 or 1) in the data.
                   10231:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   10232:    * corresponding modality (h,j).
                   10233:    */
                   10234: 
1.145     brouard  10235:   h=0;
                   10236:   /*if (cptcovn > 0) */
1.126     brouard  10237:   m=pow(2,cptcoveff);
                   10238:  
1.144     brouard  10239:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  10240:           * For k=4 covariates, h goes from 1 to m=2**k
                   10241:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   10242:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  10243:           *     h\k   1     2     3     4
1.143     brouard  10244:           *______________________________  
                   10245:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   10246:           *     2     2     1     1     1
                   10247:           *     3 i=2 1     2     1     1
                   10248:           *     4     2     2     1     1
                   10249:           *     5 i=3 1 i=2 1     2     1
                   10250:           *     6     2     1     2     1
                   10251:           *     7 i=4 1     2     2     1
                   10252:           *     8     2     2     2     1
1.197     brouard  10253:           *     9 i=5 1 i=3 1 i=2 1     2
                   10254:           *    10     2     1     1     2
                   10255:           *    11 i=6 1     2     1     2
                   10256:           *    12     2     2     1     2
                   10257:           *    13 i=7 1 i=4 1     2     2    
                   10258:           *    14     2     1     2     2
                   10259:           *    15 i=8 1     2     2     2
                   10260:           *    16     2     2     2     2
1.143     brouard  10261:           */
1.212     brouard  10262:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  10263:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   10264:      * and the value of each covariate?
                   10265:      * V1=1, V2=1, V3=2, V4=1 ?
                   10266:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   10267:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   10268:      * In order to get the real value in the data, we use nbcode
                   10269:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   10270:      * We are keeping this crazy system in order to be able (in the future?) 
                   10271:      * to have more than 2 values (0 or 1) for a covariate.
                   10272:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   10273:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   10274:      *              bbbbbbbb
                   10275:      *              76543210     
                   10276:      *   h-1        00000101 (6-1=5)
1.219     brouard  10277:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  10278:      *           &
                   10279:      *     1        00000001 (1)
1.219     brouard  10280:      *              00000000        = 1 & ((h-1) >> (k-1))
                   10281:      *          +1= 00000001 =1 
1.211     brouard  10282:      *
                   10283:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   10284:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   10285:      *    >>k'            11
                   10286:      *          &   00000001
                   10287:      *            = 00000001
                   10288:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   10289:      * Reverse h=6 and m=16?
                   10290:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   10291:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   10292:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   10293:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   10294:      * V3=decodtabm(14,3,2**4)=2
                   10295:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   10296:      *(h-1) >> (j-1)    0011 =13 >> 2
                   10297:      *          &1 000000001
                   10298:      *           = 000000001
                   10299:      *         +1= 000000010 =2
                   10300:      *                  2211
                   10301:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   10302:      *                  V3=2
1.220     brouard  10303:                 * codtabm and decodtabm are identical
1.211     brouard  10304:      */
                   10305: 
1.145     brouard  10306: 
                   10307:  free_ivector(Ndum,-1,NCOVMAX);
                   10308: 
                   10309: 
1.126     brouard  10310:     
1.186     brouard  10311:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  10312:   strcpy(optionfilegnuplot,optionfilefiname);
                   10313:   if(mle==-3)
1.201     brouard  10314:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  10315:   strcat(optionfilegnuplot,".gp");
                   10316: 
                   10317:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   10318:     printf("Problem with file %s",optionfilegnuplot);
                   10319:   }
                   10320:   else{
1.204     brouard  10321:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  10322:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  10323:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   10324:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  10325:   }
                   10326:   /*  fclose(ficgp);*/
1.186     brouard  10327: 
                   10328: 
                   10329:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  10330: 
                   10331:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   10332:   if(mle==-3)
1.201     brouard  10333:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  10334:   strcat(optionfilehtm,".htm");
                   10335:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  10336:     printf("Problem with %s \n",optionfilehtm);
                   10337:     exit(0);
1.126     brouard  10338:   }
                   10339: 
                   10340:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   10341:   strcat(optionfilehtmcov,"-cov.htm");
                   10342:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   10343:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   10344:   }
                   10345:   else{
                   10346:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   10347: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10348: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  10349:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   10350:   }
                   10351: 
1.213     brouard  10352:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  10353: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   10354: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  10355: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10356: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  10357: \n\
                   10358: <hr  size=\"2\" color=\"#EC5E5E\">\
                   10359:  <ul><li><h4>Parameter files</h4>\n\
                   10360:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   10361:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   10362:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   10363:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   10364:  - Date and time at start: %s</ul>\n",\
                   10365:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   10366:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   10367:          fileres,fileres,\
                   10368:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   10369:   fflush(fichtm);
                   10370: 
                   10371:   strcpy(pathr,path);
                   10372:   strcat(pathr,optionfilefiname);
1.184     brouard  10373: #ifdef WIN32
                   10374:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   10375: #else
1.126     brouard  10376:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  10377: #endif
                   10378:          
1.126     brouard  10379:   
1.220     brouard  10380:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   10381:                 and for any valid combination of covariates
1.126     brouard  10382:      and prints on file fileres'p'. */
1.227     brouard  10383:   freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
                   10384:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  10385: 
                   10386:   fprintf(fichtm,"\n");
                   10387:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   10388: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   10389: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   10390:          imx,agemin,agemax,jmin,jmax,jmean);
                   10391:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.220     brouard  10392:        oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10393:        newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10394:        savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10395:        oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  10396: 
1.126     brouard  10397:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   10398:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   10399:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   10400: 
                   10401:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  10402:   /* For mortality only */
1.126     brouard  10403:   if (mle==-3){
1.136     brouard  10404:     ximort=matrix(1,NDIM,1,NDIM); 
1.220     brouard  10405:                for(i=1;i<=NDIM;i++)
                   10406:                        for(j=1;j<=NDIM;j++)
                   10407:                                ximort[i][j]=0.;
1.186     brouard  10408:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  10409:     cens=ivector(1,n);
                   10410:     ageexmed=vector(1,n);
                   10411:     agecens=vector(1,n);
                   10412:     dcwave=ivector(1,n);
1.223     brouard  10413:                
1.126     brouard  10414:     for (i=1; i<=imx; i++){
                   10415:       dcwave[i]=-1;
                   10416:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  10417:        if (s[m][i]>nlstate) {
                   10418:          dcwave[i]=m;
                   10419:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   10420:          break;
                   10421:        }
1.126     brouard  10422:     }
1.226     brouard  10423:     
1.126     brouard  10424:     for (i=1; i<=imx; i++) {
                   10425:       if (wav[i]>0){
1.226     brouard  10426:        ageexmed[i]=agev[mw[1][i]][i];
                   10427:        j=wav[i];
                   10428:        agecens[i]=1.; 
                   10429:        
                   10430:        if (ageexmed[i]> 1 && wav[i] > 0){
                   10431:          agecens[i]=agev[mw[j][i]][i];
                   10432:          cens[i]= 1;
                   10433:        }else if (ageexmed[i]< 1) 
                   10434:          cens[i]= -1;
                   10435:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   10436:          cens[i]=0 ;
1.126     brouard  10437:       }
                   10438:       else cens[i]=-1;
                   10439:     }
                   10440:     
                   10441:     for (i=1;i<=NDIM;i++) {
                   10442:       for (j=1;j<=NDIM;j++)
1.226     brouard  10443:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  10444:     }
                   10445:     
1.145     brouard  10446:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  10447:     /*printf("%lf %lf", p[1], p[2]);*/
                   10448:     
                   10449:     
1.136     brouard  10450: #ifdef GSL
                   10451:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  10452: #else
1.126     brouard  10453:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  10454: #endif
1.201     brouard  10455:     strcpy(filerespow,"POW-MORT_"); 
                   10456:     strcat(filerespow,fileresu);
1.126     brouard  10457:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   10458:       printf("Problem with resultfile: %s\n", filerespow);
                   10459:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   10460:     }
1.136     brouard  10461: #ifdef GSL
                   10462:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  10463: #else
1.126     brouard  10464:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  10465: #endif
1.126     brouard  10466:     /*  for (i=1;i<=nlstate;i++)
                   10467:        for(j=1;j<=nlstate+ndeath;j++)
                   10468:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   10469:     */
                   10470:     fprintf(ficrespow,"\n");
1.136     brouard  10471: #ifdef GSL
                   10472:     /* gsl starts here */ 
                   10473:     T = gsl_multimin_fminimizer_nmsimplex;
                   10474:     gsl_multimin_fminimizer *sfm = NULL;
                   10475:     gsl_vector *ss, *x;
                   10476:     gsl_multimin_function minex_func;
                   10477: 
                   10478:     /* Initial vertex size vector */
                   10479:     ss = gsl_vector_alloc (NDIM);
                   10480:     
                   10481:     if (ss == NULL){
                   10482:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   10483:     }
                   10484:     /* Set all step sizes to 1 */
                   10485:     gsl_vector_set_all (ss, 0.001);
                   10486: 
                   10487:     /* Starting point */
1.126     brouard  10488:     
1.136     brouard  10489:     x = gsl_vector_alloc (NDIM);
                   10490:     
                   10491:     if (x == NULL){
                   10492:       gsl_vector_free(ss);
                   10493:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   10494:     }
                   10495:   
                   10496:     /* Initialize method and iterate */
                   10497:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  10498:     /*     gsl_vector_set(x, 0, 0.0268); */
                   10499:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  10500:     gsl_vector_set(x, 0, p[1]);
                   10501:     gsl_vector_set(x, 1, p[2]);
                   10502: 
                   10503:     minex_func.f = &gompertz_f;
                   10504:     minex_func.n = NDIM;
                   10505:     minex_func.params = (void *)&p; /* ??? */
                   10506:     
                   10507:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   10508:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   10509:     
                   10510:     printf("Iterations beginning .....\n\n");
                   10511:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   10512: 
                   10513:     iteri=0;
                   10514:     while (rval == GSL_CONTINUE){
                   10515:       iteri++;
                   10516:       status = gsl_multimin_fminimizer_iterate(sfm);
                   10517:       
                   10518:       if (status) printf("error: %s\n", gsl_strerror (status));
                   10519:       fflush(0);
                   10520:       
                   10521:       if (status) 
                   10522:         break;
                   10523:       
                   10524:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   10525:       ssval = gsl_multimin_fminimizer_size (sfm);
                   10526:       
                   10527:       if (rval == GSL_SUCCESS)
                   10528:         printf ("converged to a local maximum at\n");
                   10529:       
                   10530:       printf("%5d ", iteri);
                   10531:       for (it = 0; it < NDIM; it++){
                   10532:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   10533:       }
                   10534:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   10535:     }
                   10536:     
                   10537:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   10538:     
                   10539:     gsl_vector_free(x); /* initial values */
                   10540:     gsl_vector_free(ss); /* inital step size */
                   10541:     for (it=0; it<NDIM; it++){
                   10542:       p[it+1]=gsl_vector_get(sfm->x,it);
                   10543:       fprintf(ficrespow," %.12lf", p[it]);
                   10544:     }
                   10545:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   10546: #endif
                   10547: #ifdef POWELL
                   10548:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   10549: #endif  
1.126     brouard  10550:     fclose(ficrespow);
                   10551:     
1.203     brouard  10552:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  10553: 
                   10554:     for(i=1; i <=NDIM; i++)
                   10555:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  10556:                                matcov[i][j]=matcov[j][i];
1.126     brouard  10557:     
                   10558:     printf("\nCovariance matrix\n ");
1.203     brouard  10559:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  10560:     for(i=1; i <=NDIM; i++) {
                   10561:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  10562:                                printf("%f ",matcov[i][j]);
                   10563:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  10564:       }
1.203     brouard  10565:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  10566:     }
                   10567:     
                   10568:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  10569:     for (i=1;i<=NDIM;i++) {
1.126     brouard  10570:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  10571:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   10572:     }
1.126     brouard  10573:     lsurv=vector(1,AGESUP);
                   10574:     lpop=vector(1,AGESUP);
                   10575:     tpop=vector(1,AGESUP);
                   10576:     lsurv[agegomp]=100000;
                   10577:     
                   10578:     for (k=agegomp;k<=AGESUP;k++) {
                   10579:       agemortsup=k;
                   10580:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   10581:     }
                   10582:     
                   10583:     for (k=agegomp;k<agemortsup;k++)
                   10584:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   10585:     
                   10586:     for (k=agegomp;k<agemortsup;k++){
                   10587:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   10588:       sumlpop=sumlpop+lpop[k];
                   10589:     }
                   10590:     
                   10591:     tpop[agegomp]=sumlpop;
                   10592:     for (k=agegomp;k<(agemortsup-3);k++){
                   10593:       /*  tpop[k+1]=2;*/
                   10594:       tpop[k+1]=tpop[k]-lpop[k];
                   10595:     }
                   10596:     
                   10597:     
                   10598:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   10599:     for (k=agegomp;k<(agemortsup-2);k++) 
                   10600:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   10601:     
                   10602:     
                   10603:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  10604:                ageminpar=50;
                   10605:                agemaxpar=100;
1.194     brouard  10606:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   10607:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10608: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10609: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   10610:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10611: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10612: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10613:     }else{
                   10614:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   10615:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  10616:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  10617:                }
1.201     brouard  10618:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  10619:                     stepm, weightopt,\
                   10620:                     model,imx,p,matcov,agemortsup);
                   10621:     
                   10622:     free_vector(lsurv,1,AGESUP);
                   10623:     free_vector(lpop,1,AGESUP);
                   10624:     free_vector(tpop,1,AGESUP);
1.220     brouard  10625:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  10626:     free_ivector(cens,1,n);
                   10627:     free_vector(agecens,1,n);
                   10628:     free_ivector(dcwave,1,n);
1.220     brouard  10629: #ifdef GSL
1.136     brouard  10630: #endif
1.186     brouard  10631:   } /* Endof if mle==-3 mortality only */
1.205     brouard  10632:   /* Standard  */
                   10633:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   10634:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10635:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  10636:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  10637:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10638:     for (k=1; k<=npar;k++)
                   10639:       printf(" %d %8.5f",k,p[k]);
                   10640:     printf("\n");
1.205     brouard  10641:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   10642:       /* mlikeli uses func not funcone */
                   10643:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   10644:     }
                   10645:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   10646:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10647:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   10648:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10649:     }
                   10650:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  10651:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10652:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10653:     for (k=1; k<=npar;k++)
                   10654:       printf(" %d %8.5f",k,p[k]);
                   10655:     printf("\n");
                   10656:     
                   10657:     /*--------- results files --------------*/
1.224     brouard  10658:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  10659:     
                   10660:     
                   10661:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10662:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10663:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10664:     for(i=1,jk=1; i <=nlstate; i++){
                   10665:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  10666:        if (k != i) {
                   10667:          printf("%d%d ",i,k);
                   10668:          fprintf(ficlog,"%d%d ",i,k);
                   10669:          fprintf(ficres,"%1d%1d ",i,k);
                   10670:          for(j=1; j <=ncovmodel; j++){
                   10671:            printf("%12.7f ",p[jk]);
                   10672:            fprintf(ficlog,"%12.7f ",p[jk]);
                   10673:            fprintf(ficres,"%12.7f ",p[jk]);
                   10674:            jk++; 
                   10675:          }
                   10676:          printf("\n");
                   10677:          fprintf(ficlog,"\n");
                   10678:          fprintf(ficres,"\n");
                   10679:        }
1.126     brouard  10680:       }
                   10681:     }
1.203     brouard  10682:     if(mle != 0){
                   10683:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  10684:       ftolhess=ftol; /* Usually correct */
1.203     brouard  10685:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   10686:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10687:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10688:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  10689:        for(k=1; k <=(nlstate+ndeath); k++){
                   10690:          if (k != i) {
                   10691:            printf("%d%d ",i,k);
                   10692:            fprintf(ficlog,"%d%d ",i,k);
                   10693:            for(j=1; j <=ncovmodel; j++){
                   10694:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10695:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10696:              jk++; 
                   10697:            }
                   10698:            printf("\n");
                   10699:            fprintf(ficlog,"\n");
                   10700:          }
                   10701:        }
1.193     brouard  10702:       }
1.203     brouard  10703:     } /* end of hesscov and Wald tests */
1.225     brouard  10704:     
1.203     brouard  10705:     /*  */
1.126     brouard  10706:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   10707:     printf("# Scales (for hessian or gradient estimation)\n");
                   10708:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   10709:     for(i=1,jk=1; i <=nlstate; i++){
                   10710:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  10711:        if (j!=i) {
                   10712:          fprintf(ficres,"%1d%1d",i,j);
                   10713:          printf("%1d%1d",i,j);
                   10714:          fprintf(ficlog,"%1d%1d",i,j);
                   10715:          for(k=1; k<=ncovmodel;k++){
                   10716:            printf(" %.5e",delti[jk]);
                   10717:            fprintf(ficlog," %.5e",delti[jk]);
                   10718:            fprintf(ficres," %.5e",delti[jk]);
                   10719:            jk++;
                   10720:          }
                   10721:          printf("\n");
                   10722:          fprintf(ficlog,"\n");
                   10723:          fprintf(ficres,"\n");
                   10724:        }
1.126     brouard  10725:       }
                   10726:     }
                   10727:     
                   10728:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  10729:     if(mle >= 1) /* To big for the screen */
1.126     brouard  10730:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   10731:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   10732:     /* # 121 Var(a12)\n\ */
                   10733:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   10734:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   10735:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   10736:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   10737:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   10738:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   10739:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   10740:     
                   10741:     
                   10742:     /* Just to have a covariance matrix which will be more understandable
                   10743:        even is we still don't want to manage dictionary of variables
                   10744:     */
                   10745:     for(itimes=1;itimes<=2;itimes++){
                   10746:       jj=0;
                   10747:       for(i=1; i <=nlstate; i++){
1.225     brouard  10748:        for(j=1; j <=nlstate+ndeath; j++){
                   10749:          if(j==i) continue;
                   10750:          for(k=1; k<=ncovmodel;k++){
                   10751:            jj++;
                   10752:            ca[0]= k+'a'-1;ca[1]='\0';
                   10753:            if(itimes==1){
                   10754:              if(mle>=1)
                   10755:                printf("#%1d%1d%d",i,j,k);
                   10756:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   10757:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   10758:            }else{
                   10759:              if(mle>=1)
                   10760:                printf("%1d%1d%d",i,j,k);
                   10761:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   10762:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   10763:            }
                   10764:            ll=0;
                   10765:            for(li=1;li <=nlstate; li++){
                   10766:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   10767:                if(lj==li) continue;
                   10768:                for(lk=1;lk<=ncovmodel;lk++){
                   10769:                  ll++;
                   10770:                  if(ll<=jj){
                   10771:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   10772:                    if(ll<jj){
                   10773:                      if(itimes==1){
                   10774:                        if(mle>=1)
                   10775:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10776:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10777:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10778:                      }else{
                   10779:                        if(mle>=1)
                   10780:                          printf(" %.5e",matcov[jj][ll]); 
                   10781:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   10782:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   10783:                      }
                   10784:                    }else{
                   10785:                      if(itimes==1){
                   10786:                        if(mle>=1)
                   10787:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   10788:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   10789:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   10790:                      }else{
                   10791:                        if(mle>=1)
                   10792:                          printf(" %.7e",matcov[jj][ll]); 
                   10793:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   10794:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   10795:                      }
                   10796:                    }
                   10797:                  }
                   10798:                } /* end lk */
                   10799:              } /* end lj */
                   10800:            } /* end li */
                   10801:            if(mle>=1)
                   10802:              printf("\n");
                   10803:            fprintf(ficlog,"\n");
                   10804:            fprintf(ficres,"\n");
                   10805:            numlinepar++;
                   10806:          } /* end k*/
                   10807:        } /*end j */
1.126     brouard  10808:       } /* end i */
                   10809:     } /* end itimes */
                   10810:     
                   10811:     fflush(ficlog);
                   10812:     fflush(ficres);
1.225     brouard  10813:     while(fgets(line, MAXLINE, ficpar)) {
                   10814:       /* If line starts with a # it is a comment */
                   10815:       if (line[0] == '#') {
                   10816:        numlinepar++;
                   10817:        fputs(line,stdout);
                   10818:        fputs(line,ficparo);
                   10819:        fputs(line,ficlog);
                   10820:        continue;
                   10821:       }else
                   10822:        break;
                   10823:     }
                   10824:     
1.209     brouard  10825:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   10826:     /*   ungetc(c,ficpar); */
                   10827:     /*   fgets(line, MAXLINE, ficpar); */
                   10828:     /*   fputs(line,stdout); */
                   10829:     /*   fputs(line,ficparo); */
                   10830:     /* } */
                   10831:     /* ungetc(c,ficpar); */
1.126     brouard  10832:     
                   10833:     estepm=0;
1.209     brouard  10834:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  10835:       
                   10836:       if (num_filled != 6) {
                   10837:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   10838:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   10839:        goto end;
                   10840:       }
                   10841:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   10842:     }
                   10843:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   10844:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   10845:     
1.209     brouard  10846:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  10847:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   10848:     if (fage <= 2) {
                   10849:       bage = ageminpar;
                   10850:       fage = agemaxpar;
                   10851:     }
                   10852:     
                   10853:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  10854:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   10855:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  10856:                
1.186     brouard  10857:     /* Other stuffs, more or less useful */    
1.126     brouard  10858:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10859:       ungetc(c,ficpar);
                   10860:       fgets(line, MAXLINE, ficpar);
1.141     brouard  10861:       fputs(line,stdout);
1.126     brouard  10862:       fputs(line,ficparo);
                   10863:     }
                   10864:     ungetc(c,ficpar);
                   10865:     
                   10866:     fscanf(ficpar,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav);
                   10867:     fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10868:     fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10869:     printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10870:     fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10871:     
                   10872:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10873:       ungetc(c,ficpar);
                   10874:       fgets(line, MAXLINE, ficpar);
1.141     brouard  10875:       fputs(line,stdout);
1.126     brouard  10876:       fputs(line,ficparo);
                   10877:     }
                   10878:     ungetc(c,ficpar);
                   10879:     
                   10880:     
                   10881:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   10882:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   10883:     
                   10884:     fscanf(ficpar,"pop_based=%d\n",&popbased);
1.193     brouard  10885:     fprintf(ficlog,"pop_based=%d\n",popbased);
1.126     brouard  10886:     fprintf(ficparo,"pop_based=%d\n",popbased);   
                   10887:     fprintf(ficres,"pop_based=%d\n",popbased);   
                   10888:     
                   10889:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10890:       ungetc(c,ficpar);
                   10891:       fgets(line, MAXLINE, ficpar);
1.141     brouard  10892:       fputs(line,stdout);
1.238     brouard  10893:       fputs(line,ficres);
1.126     brouard  10894:       fputs(line,ficparo);
                   10895:     }
                   10896:     ungetc(c,ficpar);
                   10897:     
                   10898:     fscanf(ficpar,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj);
                   10899:     fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10900:     printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10901:     fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10902:     fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10903:     /* day and month of proj2 are not used but only year anproj2.*/
                   10904:     
1.217     brouard  10905:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10906:       ungetc(c,ficpar);
                   10907:       fgets(line, MAXLINE, ficpar);
                   10908:       fputs(line,stdout);
                   10909:       fputs(line,ficparo);
1.238     brouard  10910:       fputs(line,ficres);
1.217     brouard  10911:     }
                   10912:     ungetc(c,ficpar);
                   10913:     
                   10914:     fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);
1.223     brouard  10915:     fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   10916:     fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   10917:     fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
1.217     brouard  10918:     /* day and month of proj2 are not used but only year anproj2.*/
1.126     brouard  10919:     
1.230     brouard  10920:     /* Results */
1.235     brouard  10921:     nresult=0;
1.230     brouard  10922:     while(fgets(line, MAXLINE, ficpar)) {
                   10923:       /* If line starts with a # it is a comment */
                   10924:       if (line[0] == '#') {
                   10925:        numlinepar++;
                   10926:        fputs(line,stdout);
                   10927:        fputs(line,ficparo);
                   10928:        fputs(line,ficlog);
1.238     brouard  10929:        fputs(line,ficres);
1.230     brouard  10930:        continue;
                   10931:       }else
                   10932:        break;
                   10933:     }
1.240     brouard  10934:     if (!feof(ficpar))
1.230     brouard  10935:     while((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
1.240     brouard  10936:       if (num_filled == 0){
1.230     brouard  10937:        resultline[0]='\0';
1.240     brouard  10938:       break;
                   10939:       } else if (num_filled != 1){
1.230     brouard  10940:        printf("ERROR %d: result line should be at minimum 'result=' %s\n",num_filled, line);
                   10941:       }
1.235     brouard  10942:       nresult++; /* Sum of resultlines */
                   10943:       printf("Result %d: result=%s\n",nresult, resultline);
                   10944:       if(nresult > MAXRESULTLINES){
                   10945:        printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   10946:        fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   10947:        goto end;
                   10948:       }
                   10949:       decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
1.238     brouard  10950:       fprintf(ficparo,"result: %s\n",resultline);
                   10951:       fprintf(ficres,"result: %s\n",resultline);
                   10952:       fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  10953:       while(fgets(line, MAXLINE, ficpar)) {
                   10954:        /* If line starts with a # it is a comment */
                   10955:        if (line[0] == '#') {
                   10956:          numlinepar++;
                   10957:          fputs(line,stdout);
                   10958:          fputs(line,ficparo);
1.238     brouard  10959:          fputs(line,ficres);
1.230     brouard  10960:          fputs(line,ficlog);
                   10961:          continue;
                   10962:        }else
                   10963:          break;
                   10964:       }
                   10965:       if (feof(ficpar))
                   10966:        break;
                   10967:       else{ /* Processess output results for this combination of covariate values */
                   10968:       }                                   
1.240     brouard  10969:     } /* end while */
1.230     brouard  10970: 
                   10971: 
1.126     brouard  10972:     
1.230     brouard  10973:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  10974:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  10975:     
                   10976:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  10977:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  10978:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  10979: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10980: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  10981:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  10982: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10983: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10984:     }else{
1.218     brouard  10985:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p);
1.220     brouard  10986:     }
                   10987:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.225     brouard  10988:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,prevfcast,backcast, estepm, \
                   10989:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  10990:                
1.225     brouard  10991:     /*------------ free_vector  -------------*/
                   10992:     /*  chdir(path); */
1.220     brouard  10993:                
1.215     brouard  10994:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   10995:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   10996:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   10997:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  10998:     free_lvector(num,1,n);
                   10999:     free_vector(agedc,1,n);
                   11000:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   11001:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   11002:     fclose(ficparo);
                   11003:     fclose(ficres);
1.220     brouard  11004:                
                   11005:                
1.186     brouard  11006:     /* Other results (useful)*/
1.220     brouard  11007:                
                   11008:                
1.126     brouard  11009:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  11010:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   11011:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  11012:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  11013:     fclose(ficrespl);
                   11014: 
                   11015:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  11016:     /*#include "hpijx.h"*/
                   11017:     hPijx(p, bage, fage);
1.145     brouard  11018:     fclose(ficrespij);
1.227     brouard  11019:     
1.220     brouard  11020:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  11021:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  11022:     k=1;
1.126     brouard  11023:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  11024:     
1.219     brouard  11025:     /* Prevalence for each covariates in probs[age][status][cov] */
1.218     brouard  11026:     probs= ma3x(1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.126     brouard  11027:     for(i=1;i<=AGESUP;i++)
1.219     brouard  11028:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  11029:        for(k=1;k<=ncovcombmax;k++)
                   11030:          probs[i][j][k]=0.;
1.219     brouard  11031:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
                   11032:     if (mobilav!=0 ||mobilavproj !=0 ) {
                   11033:       mobaverages= ma3x(1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.227     brouard  11034:       for(i=1;i<=AGESUP;i++)
                   11035:        for(j=1;j<=nlstate;j++)
                   11036:          for(k=1;k<=ncovcombmax;k++)
                   11037:            mobaverages[i][j][k]=0.;
1.219     brouard  11038:       mobaverage=mobaverages;
                   11039:       if (mobilav!=0) {
1.235     brouard  11040:        printf("Movingaveraging observed prevalence\n");
1.227     brouard  11041:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   11042:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   11043:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   11044:        }
1.219     brouard  11045:       }
                   11046:       /* /\* Prevalence for each covariates in probs[age][status][cov] *\/ */
                   11047:       /* prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   11048:       else if (mobilavproj !=0) {
1.235     brouard  11049:        printf("Movingaveraging projected observed prevalence\n");
1.227     brouard  11050:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   11051:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11052:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11053:        }
1.219     brouard  11054:       }
                   11055:     }/* end if moving average */
1.227     brouard  11056:     
1.126     brouard  11057:     /*---------- Forecasting ------------------*/
                   11058:     /*if((stepm == 1) && (strcmp(model,".")==0)){*/
                   11059:     if(prevfcast==1){
                   11060:       /*    if(stepm ==1){*/
1.225     brouard  11061:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  11062:     }
1.217     brouard  11063:     if(backcast==1){
1.219     brouard  11064:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11065:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11066:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   11067: 
                   11068:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   11069: 
                   11070:       bprlim=matrix(1,nlstate,1,nlstate);
                   11071:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   11072:       fclose(ficresplb);
                   11073: 
1.222     brouard  11074:       hBijx(p, bage, fage, mobaverage);
                   11075:       fclose(ficrespijb);
1.219     brouard  11076:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11077: 
                   11078:       /* prevbackforecast(fileresu, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, mobilavproj,
1.225     brouard  11079:         bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
1.219     brouard  11080:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11081:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11082:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11083:     }
1.217     brouard  11084:     
1.186     brouard  11085:  
                   11086:     /* ------ Other prevalence ratios------------ */
1.126     brouard  11087: 
1.215     brouard  11088:     free_ivector(wav,1,imx);
                   11089:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   11090:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   11091:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  11092:                
                   11093:                
1.127     brouard  11094:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  11095:                
1.201     brouard  11096:     strcpy(filerese,"E_");
                   11097:     strcat(filerese,fileresu);
1.126     brouard  11098:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   11099:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11100:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11101:     }
1.208     brouard  11102:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   11103:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  11104: 
                   11105:     pstamp(ficreseij);
1.219     brouard  11106:                
1.235     brouard  11107:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11108:     if (cptcovn < 1){i1=1;}
                   11109:     
                   11110:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11111:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
                   11112:       if(TKresult[nres]!= k)
                   11113:        continue;
1.219     brouard  11114:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  11115:       printf("\n#****** ");
1.225     brouard  11116:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11117:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11118:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11119:       }
                   11120:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11121:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11122:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  11123:       }
                   11124:       fprintf(ficreseij,"******\n");
1.235     brouard  11125:       printf("******\n");
1.219     brouard  11126:       
                   11127:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11128:       oldm=oldms;savm=savms;
1.235     brouard  11129:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  11130:       
1.219     brouard  11131:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  11132:     }
                   11133:     fclose(ficreseij);
1.208     brouard  11134:     printf("done evsij\n");fflush(stdout);
                   11135:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.218     brouard  11136:                
1.227     brouard  11137:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  11138:                
                   11139:                
1.201     brouard  11140:     strcpy(filerest,"T_");
                   11141:     strcat(filerest,fileresu);
1.127     brouard  11142:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   11143:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   11144:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   11145:     }
1.208     brouard  11146:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   11147:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.218     brouard  11148:                
1.126     brouard  11149: 
1.201     brouard  11150:     strcpy(fileresstde,"STDE_");
                   11151:     strcat(fileresstde,fileresu);
1.126     brouard  11152:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  11153:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   11154:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  11155:     }
1.227     brouard  11156:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   11157:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  11158: 
1.201     brouard  11159:     strcpy(filerescve,"CVE_");
                   11160:     strcat(filerescve,fileresu);
1.126     brouard  11161:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  11162:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   11163:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  11164:     }
1.227     brouard  11165:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   11166:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  11167: 
1.201     brouard  11168:     strcpy(fileresv,"V_");
                   11169:     strcat(fileresv,fileresu);
1.126     brouard  11170:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   11171:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11172:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11173:     }
1.227     brouard  11174:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   11175:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  11176: 
1.145     brouard  11177:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11178:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   11179:           
1.235     brouard  11180:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11181:     if (cptcovn < 1){i1=1;}
                   11182:     
                   11183:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11184:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
                   11185:       if(TKresult[nres]!= k)
                   11186:        continue;
1.242     brouard  11187:       printf("\n#****** Result for:");
                   11188:       fprintf(ficrest,"\n#****** Result for:");
                   11189:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  11190:       for(j=1;j<=cptcoveff;j++){ 
                   11191:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11192:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11193:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11194:       }
1.235     brouard  11195:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11196:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11197:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11198:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11199:       }        
1.208     brouard  11200:       fprintf(ficrest,"******\n");
1.227     brouard  11201:       fprintf(ficlog,"******\n");
                   11202:       printf("******\n");
1.208     brouard  11203:       
                   11204:       fprintf(ficresstdeij,"\n#****** ");
                   11205:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  11206:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11207:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11208:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  11209:       }
1.235     brouard  11210:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11211:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11212:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11213:       }        
1.208     brouard  11214:       fprintf(ficresstdeij,"******\n");
                   11215:       fprintf(ficrescveij,"******\n");
                   11216:       
                   11217:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  11218:       /* pstamp(ficresvij); */
1.225     brouard  11219:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  11220:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11221:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11222:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11223:       }        
1.208     brouard  11224:       fprintf(ficresvij,"******\n");
                   11225:       
                   11226:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11227:       oldm=oldms;savm=savms;
1.235     brouard  11228:       printf(" cvevsij ");
                   11229:       fprintf(ficlog, " cvevsij ");
                   11230:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  11231:       printf(" end cvevsij \n ");
                   11232:       fprintf(ficlog, " end cvevsij \n ");
                   11233:       
                   11234:       /*
                   11235:        */
                   11236:       /* goto endfree; */
                   11237:       
                   11238:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11239:       pstamp(ficrest);
                   11240:       
                   11241:       
                   11242:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  11243:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   11244:        cptcod= 0; /* To be deleted */
                   11245:        printf("varevsij vpopbased=%d \n",vpopbased);
                   11246:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  11247:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  11248:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   11249:        if(vpopbased==1)
                   11250:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   11251:        else
                   11252:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   11253:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   11254:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   11255:        fprintf(ficrest,"\n");
                   11256:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   11257:        epj=vector(1,nlstate+1);
                   11258:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   11259:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   11260:        for(age=bage; age <=fage ;age++){
1.235     brouard  11261:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  11262:          if (vpopbased==1) {
                   11263:            if(mobilav ==0){
                   11264:              for(i=1; i<=nlstate;i++)
                   11265:                prlim[i][i]=probs[(int)age][i][k];
                   11266:            }else{ /* mobilav */ 
                   11267:              for(i=1; i<=nlstate;i++)
                   11268:                prlim[i][i]=mobaverage[(int)age][i][k];
                   11269:            }
                   11270:          }
1.219     brouard  11271:          
1.227     brouard  11272:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   11273:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   11274:          /* printf(" age %4.0f ",age); */
                   11275:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   11276:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   11277:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   11278:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   11279:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   11280:            }
                   11281:            epj[nlstate+1] +=epj[j];
                   11282:          }
                   11283:          /* printf(" age %4.0f \n",age); */
1.219     brouard  11284:          
1.227     brouard  11285:          for(i=1, vepp=0.;i <=nlstate;i++)
                   11286:            for(j=1;j <=nlstate;j++)
                   11287:              vepp += vareij[i][j][(int)age];
                   11288:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   11289:          for(j=1;j <=nlstate;j++){
                   11290:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   11291:          }
                   11292:          fprintf(ficrest,"\n");
                   11293:        }
1.208     brouard  11294:       } /* End vpopbased */
                   11295:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11296:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11297:       free_vector(epj,1,nlstate+1);
1.235     brouard  11298:       printf("done selection\n");fflush(stdout);
                   11299:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  11300:       
1.145     brouard  11301:       /*}*/
1.235     brouard  11302:     } /* End k selection */
1.227     brouard  11303: 
                   11304:     printf("done State-specific expectancies\n");fflush(stdout);
                   11305:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   11306: 
1.126     brouard  11307:     /*------- Variance of period (stable) prevalence------*/   
1.227     brouard  11308:     
1.201     brouard  11309:     strcpy(fileresvpl,"VPL_");
                   11310:     strcat(fileresvpl,fileresu);
1.126     brouard  11311:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   11312:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   11313:       exit(0);
                   11314:     }
1.208     brouard  11315:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   11316:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.227     brouard  11317:     
1.145     brouard  11318:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11319:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
1.227     brouard  11320:     
1.235     brouard  11321:     i1=pow(2,cptcoveff);
                   11322:     if (cptcovn < 1){i1=1;}
                   11323: 
                   11324:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11325:     for(k=1; k<=i1;k++){
                   11326:       if(TKresult[nres]!= k)
                   11327:        continue;
1.227     brouard  11328:       fprintf(ficresvpl,"\n#****** ");
                   11329:       printf("\n#****** ");
                   11330:       fprintf(ficlog,"\n#****** ");
                   11331:       for(j=1;j<=cptcoveff;j++) {
                   11332:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11333:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11334:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11335:       }
1.235     brouard  11336:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11337:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11338:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11339:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11340:       }        
1.227     brouard  11341:       fprintf(ficresvpl,"******\n");
                   11342:       printf("******\n");
                   11343:       fprintf(ficlog,"******\n");
                   11344:       
                   11345:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   11346:       oldm=oldms;savm=savms;
1.235     brouard  11347:       varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, strstart, nres);
1.227     brouard  11348:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
1.145     brouard  11349:       /*}*/
1.126     brouard  11350:     }
1.227     brouard  11351:     
1.126     brouard  11352:     fclose(ficresvpl);
1.208     brouard  11353:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   11354:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
1.227     brouard  11355:     
                   11356:     free_vector(weight,1,n);
                   11357:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   11358:     free_imatrix(s,1,maxwav+1,1,n);
                   11359:     free_matrix(anint,1,maxwav,1,n); 
                   11360:     free_matrix(mint,1,maxwav,1,n);
                   11361:     free_ivector(cod,1,n);
                   11362:     free_ivector(tab,1,NCOVMAX);
                   11363:     fclose(ficresstdeij);
                   11364:     fclose(ficrescveij);
                   11365:     fclose(ficresvij);
                   11366:     fclose(ficrest);
                   11367:     fclose(ficpar);
                   11368:     
                   11369:     
1.126     brouard  11370:     /*---------- End : free ----------------*/
1.219     brouard  11371:     if (mobilav!=0 ||mobilavproj !=0)
                   11372:       free_ma3x(mobaverages,1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
1.218     brouard  11373:     free_ma3x(probs,1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  11374:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11375:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  11376:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  11377:   /* endfree:*/
                   11378:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11379:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11380:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11381:   free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
1.233     brouard  11382:   free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
1.227     brouard  11383:   free_matrix(coqvar,1,maxwav,1,n);
                   11384:   free_matrix(covar,0,NCOVMAX,1,n);
                   11385:   free_matrix(matcov,1,npar,1,npar);
                   11386:   free_matrix(hess,1,npar,1,npar);
                   11387:   /*free_vector(delti,1,npar);*/
                   11388:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11389:   free_matrix(agev,1,maxwav,1,imx);
                   11390:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   11391:   
                   11392:   free_ivector(ncodemax,1,NCOVMAX);
                   11393:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   11394:   free_ivector(Dummy,-1,NCOVMAX);
                   11395:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  11396:   free_ivector(DummyV,1,NCOVMAX);
                   11397:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  11398:   free_ivector(Typevar,-1,NCOVMAX);
                   11399:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  11400:   free_ivector(TvarsQ,1,NCOVMAX);
                   11401:   free_ivector(TvarsQind,1,NCOVMAX);
                   11402:   free_ivector(TvarsD,1,NCOVMAX);
                   11403:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  11404:   free_ivector(TvarFD,1,NCOVMAX);
                   11405:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  11406:   free_ivector(TvarF,1,NCOVMAX);
                   11407:   free_ivector(TvarFind,1,NCOVMAX);
                   11408:   free_ivector(TvarV,1,NCOVMAX);
                   11409:   free_ivector(TvarVind,1,NCOVMAX);
                   11410:   free_ivector(TvarA,1,NCOVMAX);
                   11411:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  11412:   free_ivector(TvarFQ,1,NCOVMAX);
                   11413:   free_ivector(TvarFQind,1,NCOVMAX);
                   11414:   free_ivector(TvarVD,1,NCOVMAX);
                   11415:   free_ivector(TvarVDind,1,NCOVMAX);
                   11416:   free_ivector(TvarVQ,1,NCOVMAX);
                   11417:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  11418:   free_ivector(Tvarsel,1,NCOVMAX);
                   11419:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  11420:   free_ivector(Tposprod,1,NCOVMAX);
                   11421:   free_ivector(Tprod,1,NCOVMAX);
                   11422:   free_ivector(Tvaraff,1,NCOVMAX);
                   11423:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   11424:   free_ivector(Tage,1,NCOVMAX);
                   11425:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  11426:   free_ivector(TmodelInvind,1,NCOVMAX);
                   11427:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  11428:   
                   11429:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   11430:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  11431:   fflush(fichtm);
                   11432:   fflush(ficgp);
                   11433:   
1.227     brouard  11434:   
1.126     brouard  11435:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  11436:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   11437:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  11438:   }else{
                   11439:     printf("End of Imach\n");
                   11440:     fprintf(ficlog,"End of Imach\n");
                   11441:   }
                   11442:   printf("See log file on %s\n",filelog);
                   11443:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  11444:   /*(void) gettimeofday(&end_time,&tzp);*/
                   11445:   rend_time = time(NULL);  
                   11446:   end_time = *localtime(&rend_time);
                   11447:   /* tml = *localtime(&end_time.tm_sec); */
                   11448:   strcpy(strtend,asctime(&end_time));
1.126     brouard  11449:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   11450:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  11451:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  11452:   
1.157     brouard  11453:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   11454:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   11455:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  11456:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   11457: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   11458:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11459:   fclose(fichtm);
                   11460:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11461:   fclose(fichtmcov);
                   11462:   fclose(ficgp);
                   11463:   fclose(ficlog);
                   11464:   /*------ End -----------*/
1.227     brouard  11465:   
                   11466:   
                   11467:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  11468: #ifdef WIN32
1.227     brouard  11469:   if (_chdir(pathcd) != 0)
                   11470:     printf("Can't move to directory %s!\n",path);
                   11471:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  11472: #else
1.227     brouard  11473:     if(chdir(pathcd) != 0)
                   11474:       printf("Can't move to directory %s!\n", path);
                   11475:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  11476: #endif 
1.126     brouard  11477:     printf("Current directory %s!\n",pathcd);
                   11478:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   11479:   sprintf(plotcmd,"gnuplot");
1.157     brouard  11480: #ifdef _WIN32
1.126     brouard  11481:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   11482: #endif
                   11483:   if(!stat(plotcmd,&info)){
1.158     brouard  11484:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11485:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  11486:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  11487:     }else
                   11488:       strcpy(pplotcmd,plotcmd);
1.157     brouard  11489: #ifdef __unix
1.126     brouard  11490:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   11491:     if(!stat(plotcmd,&info)){
1.158     brouard  11492:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11493:     }else
                   11494:       strcpy(pplotcmd,plotcmd);
                   11495: #endif
                   11496:   }else
                   11497:     strcpy(pplotcmd,plotcmd);
                   11498:   
                   11499:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  11500:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  11501:   
1.126     brouard  11502:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  11503:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  11504:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  11505:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  11506:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  11507:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  11508:   }
1.158     brouard  11509:   printf(" Successful, please wait...");
1.126     brouard  11510:   while (z[0] != 'q') {
                   11511:     /* chdir(path); */
1.154     brouard  11512:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  11513:     scanf("%s",z);
                   11514: /*     if (z[0] == 'c') system("./imach"); */
                   11515:     if (z[0] == 'e') {
1.158     brouard  11516: #ifdef __APPLE__
1.152     brouard  11517:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  11518: #elif __linux
                   11519:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  11520: #else
1.152     brouard  11521:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  11522: #endif
                   11523:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   11524:       system(pplotcmd);
1.126     brouard  11525:     }
                   11526:     else if (z[0] == 'g') system(plotcmd);
                   11527:     else if (z[0] == 'q') exit(0);
                   11528:   }
1.227     brouard  11529: end:
1.126     brouard  11530:   while (z[0] != 'q') {
1.195     brouard  11531:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  11532:     scanf("%s",z);
                   11533:   }
                   11534: }

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