Annotation of imach/src/imach.c, revision 1.246

1.246   ! brouard     1: /* $Id: imach.c,v 1.245 2016/09/02 07:25:01 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.246   ! brouard     4:   Revision 1.245  2016/09/02 07:25:01  brouard
        !             5:   *** empty log message ***
        !             6: 
1.245     brouard     7:   Revision 1.244  2016/09/02 07:17:34  brouard
                      8:   *** empty log message ***
                      9: 
1.244     brouard    10:   Revision 1.243  2016/09/02 06:45:35  brouard
                     11:   *** empty log message ***
                     12: 
1.243     brouard    13:   Revision 1.242  2016/08/30 15:01:20  brouard
                     14:   Summary: Fixing a lots
                     15: 
1.242     brouard    16:   Revision 1.241  2016/08/29 17:17:25  brouard
                     17:   Summary: gnuplot problem in Back projection to fix
                     18: 
1.241     brouard    19:   Revision 1.240  2016/08/29 07:53:18  brouard
                     20:   Summary: Better
                     21: 
1.240     brouard    22:   Revision 1.239  2016/08/26 15:51:03  brouard
                     23:   Summary: Improvement in Powell output in order to copy and paste
                     24: 
                     25:   Author:
                     26: 
1.239     brouard    27:   Revision 1.238  2016/08/26 14:23:35  brouard
                     28:   Summary: Starting tests of 0.99
                     29: 
1.238     brouard    30:   Revision 1.237  2016/08/26 09:20:19  brouard
                     31:   Summary: to valgrind
                     32: 
1.237     brouard    33:   Revision 1.236  2016/08/25 10:50:18  brouard
                     34:   *** empty log message ***
                     35: 
1.236     brouard    36:   Revision 1.235  2016/08/25 06:59:23  brouard
                     37:   *** empty log message ***
                     38: 
1.235     brouard    39:   Revision 1.234  2016/08/23 16:51:20  brouard
                     40:   *** empty log message ***
                     41: 
1.234     brouard    42:   Revision 1.233  2016/08/23 07:40:50  brouard
                     43:   Summary: not working
                     44: 
1.233     brouard    45:   Revision 1.232  2016/08/22 14:20:21  brouard
                     46:   Summary: not working
                     47: 
1.232     brouard    48:   Revision 1.231  2016/08/22 07:17:15  brouard
                     49:   Summary: not working
                     50: 
1.231     brouard    51:   Revision 1.230  2016/08/22 06:55:53  brouard
                     52:   Summary: Not working
                     53: 
1.230     brouard    54:   Revision 1.229  2016/07/23 09:45:53  brouard
                     55:   Summary: Completing for func too
                     56: 
1.229     brouard    57:   Revision 1.228  2016/07/22 17:45:30  brouard
                     58:   Summary: Fixing some arrays, still debugging
                     59: 
1.227     brouard    60:   Revision 1.226  2016/07/12 18:42:34  brouard
                     61:   Summary: temp
                     62: 
1.226     brouard    63:   Revision 1.225  2016/07/12 08:40:03  brouard
                     64:   Summary: saving but not running
                     65: 
1.225     brouard    66:   Revision 1.224  2016/07/01 13:16:01  brouard
                     67:   Summary: Fixes
                     68: 
1.224     brouard    69:   Revision 1.223  2016/02/19 09:23:35  brouard
                     70:   Summary: temporary
                     71: 
1.223     brouard    72:   Revision 1.222  2016/02/17 08:14:50  brouard
                     73:   Summary: Probably last 0.98 stable version 0.98r6
                     74: 
1.222     brouard    75:   Revision 1.221  2016/02/15 23:35:36  brouard
                     76:   Summary: minor bug
                     77: 
1.220     brouard    78:   Revision 1.219  2016/02/15 00:48:12  brouard
                     79:   *** empty log message ***
                     80: 
1.219     brouard    81:   Revision 1.218  2016/02/12 11:29:23  brouard
                     82:   Summary: 0.99 Back projections
                     83: 
1.218     brouard    84:   Revision 1.217  2015/12/23 17:18:31  brouard
                     85:   Summary: Experimental backcast
                     86: 
1.217     brouard    87:   Revision 1.216  2015/12/18 17:32:11  brouard
                     88:   Summary: 0.98r4 Warning and status=-2
                     89: 
                     90:   Version 0.98r4 is now:
                     91:    - displaying an error when status is -1, date of interview unknown and date of death known;
                     92:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                     93:   Older changes concerning s=-2, dating from 2005 have been supersed.
                     94: 
1.216     brouard    95:   Revision 1.215  2015/12/16 08:52:24  brouard
                     96:   Summary: 0.98r4 working
                     97: 
1.215     brouard    98:   Revision 1.214  2015/12/16 06:57:54  brouard
                     99:   Summary: temporary not working
                    100: 
1.214     brouard   101:   Revision 1.213  2015/12/11 18:22:17  brouard
                    102:   Summary: 0.98r4
                    103: 
1.213     brouard   104:   Revision 1.212  2015/11/21 12:47:24  brouard
                    105:   Summary: minor typo
                    106: 
1.212     brouard   107:   Revision 1.211  2015/11/21 12:41:11  brouard
                    108:   Summary: 0.98r3 with some graph of projected cross-sectional
                    109: 
                    110:   Author: Nicolas Brouard
                    111: 
1.211     brouard   112:   Revision 1.210  2015/11/18 17:41:20  brouard
                    113:   Summary: Start working on projected prevalences
                    114: 
1.210     brouard   115:   Revision 1.209  2015/11/17 22:12:03  brouard
                    116:   Summary: Adding ftolpl parameter
                    117:   Author: N Brouard
                    118: 
                    119:   We had difficulties to get smoothed confidence intervals. It was due
                    120:   to the period prevalence which wasn't computed accurately. The inner
                    121:   parameter ftolpl is now an outer parameter of the .imach parameter
                    122:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    123:   computation are long.
                    124: 
1.209     brouard   125:   Revision 1.208  2015/11/17 14:31:57  brouard
                    126:   Summary: temporary
                    127: 
1.208     brouard   128:   Revision 1.207  2015/10/27 17:36:57  brouard
                    129:   *** empty log message ***
                    130: 
1.207     brouard   131:   Revision 1.206  2015/10/24 07:14:11  brouard
                    132:   *** empty log message ***
                    133: 
1.206     brouard   134:   Revision 1.205  2015/10/23 15:50:53  brouard
                    135:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    136: 
1.205     brouard   137:   Revision 1.204  2015/10/01 16:20:26  brouard
                    138:   Summary: Some new graphs of contribution to likelihood
                    139: 
1.204     brouard   140:   Revision 1.203  2015/09/30 17:45:14  brouard
                    141:   Summary: looking at better estimation of the hessian
                    142: 
                    143:   Also a better criteria for convergence to the period prevalence And
                    144:   therefore adding the number of years needed to converge. (The
                    145:   prevalence in any alive state shold sum to one
                    146: 
1.203     brouard   147:   Revision 1.202  2015/09/22 19:45:16  brouard
                    148:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    149: 
1.202     brouard   150:   Revision 1.201  2015/09/15 17:34:58  brouard
                    151:   Summary: 0.98r0
                    152: 
                    153:   - Some new graphs like suvival functions
                    154:   - Some bugs fixed like model=1+age+V2.
                    155: 
1.201     brouard   156:   Revision 1.200  2015/09/09 16:53:55  brouard
                    157:   Summary: Big bug thanks to Flavia
                    158: 
                    159:   Even model=1+age+V2. did not work anymore
                    160: 
1.200     brouard   161:   Revision 1.199  2015/09/07 14:09:23  brouard
                    162:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    163: 
1.199     brouard   164:   Revision 1.198  2015/09/03 07:14:39  brouard
                    165:   Summary: 0.98q5 Flavia
                    166: 
1.198     brouard   167:   Revision 1.197  2015/09/01 18:24:39  brouard
                    168:   *** empty log message ***
                    169: 
1.197     brouard   170:   Revision 1.196  2015/08/18 23:17:52  brouard
                    171:   Summary: 0.98q5
                    172: 
1.196     brouard   173:   Revision 1.195  2015/08/18 16:28:39  brouard
                    174:   Summary: Adding a hack for testing purpose
                    175: 
                    176:   After reading the title, ftol and model lines, if the comment line has
                    177:   a q, starting with #q, the answer at the end of the run is quit. It
                    178:   permits to run test files in batch with ctest. The former workaround was
                    179:   $ echo q | imach foo.imach
                    180: 
1.195     brouard   181:   Revision 1.194  2015/08/18 13:32:00  brouard
                    182:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    183: 
1.194     brouard   184:   Revision 1.193  2015/08/04 07:17:42  brouard
                    185:   Summary: 0.98q4
                    186: 
1.193     brouard   187:   Revision 1.192  2015/07/16 16:49:02  brouard
                    188:   Summary: Fixing some outputs
                    189: 
1.192     brouard   190:   Revision 1.191  2015/07/14 10:00:33  brouard
                    191:   Summary: Some fixes
                    192: 
1.191     brouard   193:   Revision 1.190  2015/05/05 08:51:13  brouard
                    194:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    195: 
                    196:   Fix 1+age+.
                    197: 
1.190     brouard   198:   Revision 1.189  2015/04/30 14:45:16  brouard
                    199:   Summary: 0.98q2
                    200: 
1.189     brouard   201:   Revision 1.188  2015/04/30 08:27:53  brouard
                    202:   *** empty log message ***
                    203: 
1.188     brouard   204:   Revision 1.187  2015/04/29 09:11:15  brouard
                    205:   *** empty log message ***
                    206: 
1.187     brouard   207:   Revision 1.186  2015/04/23 12:01:52  brouard
                    208:   Summary: V1*age is working now, version 0.98q1
                    209: 
                    210:   Some codes had been disabled in order to simplify and Vn*age was
                    211:   working in the optimization phase, ie, giving correct MLE parameters,
                    212:   but, as usual, outputs were not correct and program core dumped.
                    213: 
1.186     brouard   214:   Revision 1.185  2015/03/11 13:26:42  brouard
                    215:   Summary: Inclusion of compile and links command line for Intel Compiler
                    216: 
1.185     brouard   217:   Revision 1.184  2015/03/11 11:52:39  brouard
                    218:   Summary: Back from Windows 8. Intel Compiler
                    219: 
1.184     brouard   220:   Revision 1.183  2015/03/10 20:34:32  brouard
                    221:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    222: 
                    223:   We use directest instead of original Powell test; probably no
                    224:   incidence on the results, but better justifications;
                    225:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    226:   wrong results.
                    227: 
1.183     brouard   228:   Revision 1.182  2015/02/12 08:19:57  brouard
                    229:   Summary: Trying to keep directest which seems simpler and more general
                    230:   Author: Nicolas Brouard
                    231: 
1.182     brouard   232:   Revision 1.181  2015/02/11 23:22:24  brouard
                    233:   Summary: Comments on Powell added
                    234: 
                    235:   Author:
                    236: 
1.181     brouard   237:   Revision 1.180  2015/02/11 17:33:45  brouard
                    238:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    239: 
1.180     brouard   240:   Revision 1.179  2015/01/04 09:57:06  brouard
                    241:   Summary: back to OS/X
                    242: 
1.179     brouard   243:   Revision 1.178  2015/01/04 09:35:48  brouard
                    244:   *** empty log message ***
                    245: 
1.178     brouard   246:   Revision 1.177  2015/01/03 18:40:56  brouard
                    247:   Summary: Still testing ilc32 on OSX
                    248: 
1.177     brouard   249:   Revision 1.176  2015/01/03 16:45:04  brouard
                    250:   *** empty log message ***
                    251: 
1.176     brouard   252:   Revision 1.175  2015/01/03 16:33:42  brouard
                    253:   *** empty log message ***
                    254: 
1.175     brouard   255:   Revision 1.174  2015/01/03 16:15:49  brouard
                    256:   Summary: Still in cross-compilation
                    257: 
1.174     brouard   258:   Revision 1.173  2015/01/03 12:06:26  brouard
                    259:   Summary: trying to detect cross-compilation
                    260: 
1.173     brouard   261:   Revision 1.172  2014/12/27 12:07:47  brouard
                    262:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    263: 
1.172     brouard   264:   Revision 1.171  2014/12/23 13:26:59  brouard
                    265:   Summary: Back from Visual C
                    266: 
                    267:   Still problem with utsname.h on Windows
                    268: 
1.171     brouard   269:   Revision 1.170  2014/12/23 11:17:12  brouard
                    270:   Summary: Cleaning some \%% back to %%
                    271: 
                    272:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    273: 
1.170     brouard   274:   Revision 1.169  2014/12/22 23:08:31  brouard
                    275:   Summary: 0.98p
                    276: 
                    277:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    278: 
1.169     brouard   279:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   280:   Summary: update
1.169     brouard   281: 
1.168     brouard   282:   Revision 1.167  2014/12/22 13:50:56  brouard
                    283:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    284: 
                    285:   Testing on Linux 64
                    286: 
1.167     brouard   287:   Revision 1.166  2014/12/22 11:40:47  brouard
                    288:   *** empty log message ***
                    289: 
1.166     brouard   290:   Revision 1.165  2014/12/16 11:20:36  brouard
                    291:   Summary: After compiling on Visual C
                    292: 
                    293:   * imach.c (Module): Merging 1.61 to 1.162
                    294: 
1.165     brouard   295:   Revision 1.164  2014/12/16 10:52:11  brouard
                    296:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    297: 
                    298:   * imach.c (Module): Merging 1.61 to 1.162
                    299: 
1.164     brouard   300:   Revision 1.163  2014/12/16 10:30:11  brouard
                    301:   * imach.c (Module): Merging 1.61 to 1.162
                    302: 
1.163     brouard   303:   Revision 1.162  2014/09/25 11:43:39  brouard
                    304:   Summary: temporary backup 0.99!
                    305: 
1.162     brouard   306:   Revision 1.1  2014/09/16 11:06:58  brouard
                    307:   Summary: With some code (wrong) for nlopt
                    308: 
                    309:   Author:
                    310: 
                    311:   Revision 1.161  2014/09/15 20:41:41  brouard
                    312:   Summary: Problem with macro SQR on Intel compiler
                    313: 
1.161     brouard   314:   Revision 1.160  2014/09/02 09:24:05  brouard
                    315:   *** empty log message ***
                    316: 
1.160     brouard   317:   Revision 1.159  2014/09/01 10:34:10  brouard
                    318:   Summary: WIN32
                    319:   Author: Brouard
                    320: 
1.159     brouard   321:   Revision 1.158  2014/08/27 17:11:51  brouard
                    322:   *** empty log message ***
                    323: 
1.158     brouard   324:   Revision 1.157  2014/08/27 16:26:55  brouard
                    325:   Summary: Preparing windows Visual studio version
                    326:   Author: Brouard
                    327: 
                    328:   In order to compile on Visual studio, time.h is now correct and time_t
                    329:   and tm struct should be used. difftime should be used but sometimes I
                    330:   just make the differences in raw time format (time(&now).
                    331:   Trying to suppress #ifdef LINUX
                    332:   Add xdg-open for __linux in order to open default browser.
                    333: 
1.157     brouard   334:   Revision 1.156  2014/08/25 20:10:10  brouard
                    335:   *** empty log message ***
                    336: 
1.156     brouard   337:   Revision 1.155  2014/08/25 18:32:34  brouard
                    338:   Summary: New compile, minor changes
                    339:   Author: Brouard
                    340: 
1.155     brouard   341:   Revision 1.154  2014/06/20 17:32:08  brouard
                    342:   Summary: Outputs now all graphs of convergence to period prevalence
                    343: 
1.154     brouard   344:   Revision 1.153  2014/06/20 16:45:46  brouard
                    345:   Summary: If 3 live state, convergence to period prevalence on same graph
                    346:   Author: Brouard
                    347: 
1.153     brouard   348:   Revision 1.152  2014/06/18 17:54:09  brouard
                    349:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    350: 
1.152     brouard   351:   Revision 1.151  2014/06/18 16:43:30  brouard
                    352:   *** empty log message ***
                    353: 
1.151     brouard   354:   Revision 1.150  2014/06/18 16:42:35  brouard
                    355:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    356:   Author: brouard
                    357: 
1.150     brouard   358:   Revision 1.149  2014/06/18 15:51:14  brouard
                    359:   Summary: Some fixes in parameter files errors
                    360:   Author: Nicolas Brouard
                    361: 
1.149     brouard   362:   Revision 1.148  2014/06/17 17:38:48  brouard
                    363:   Summary: Nothing new
                    364:   Author: Brouard
                    365: 
                    366:   Just a new packaging for OS/X version 0.98nS
                    367: 
1.148     brouard   368:   Revision 1.147  2014/06/16 10:33:11  brouard
                    369:   *** empty log message ***
                    370: 
1.147     brouard   371:   Revision 1.146  2014/06/16 10:20:28  brouard
                    372:   Summary: Merge
                    373:   Author: Brouard
                    374: 
                    375:   Merge, before building revised version.
                    376: 
1.146     brouard   377:   Revision 1.145  2014/06/10 21:23:15  brouard
                    378:   Summary: Debugging with valgrind
                    379:   Author: Nicolas Brouard
                    380: 
                    381:   Lot of changes in order to output the results with some covariates
                    382:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    383:   improve the code.
                    384:   No more memory valgrind error but a lot has to be done in order to
                    385:   continue the work of splitting the code into subroutines.
                    386:   Also, decodemodel has been improved. Tricode is still not
                    387:   optimal. nbcode should be improved. Documentation has been added in
                    388:   the source code.
                    389: 
1.144     brouard   390:   Revision 1.143  2014/01/26 09:45:38  brouard
                    391:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    392: 
                    393:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    394:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    395: 
1.143     brouard   396:   Revision 1.142  2014/01/26 03:57:36  brouard
                    397:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    398: 
                    399:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    400: 
1.142     brouard   401:   Revision 1.141  2014/01/26 02:42:01  brouard
                    402:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    403: 
1.141     brouard   404:   Revision 1.140  2011/09/02 10:37:54  brouard
                    405:   Summary: times.h is ok with mingw32 now.
                    406: 
1.140     brouard   407:   Revision 1.139  2010/06/14 07:50:17  brouard
                    408:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    409:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    410: 
1.139     brouard   411:   Revision 1.138  2010/04/30 18:19:40  brouard
                    412:   *** empty log message ***
                    413: 
1.138     brouard   414:   Revision 1.137  2010/04/29 18:11:38  brouard
                    415:   (Module): Checking covariates for more complex models
                    416:   than V1+V2. A lot of change to be done. Unstable.
                    417: 
1.137     brouard   418:   Revision 1.136  2010/04/26 20:30:53  brouard
                    419:   (Module): merging some libgsl code. Fixing computation
                    420:   of likelione (using inter/intrapolation if mle = 0) in order to
                    421:   get same likelihood as if mle=1.
                    422:   Some cleaning of code and comments added.
                    423: 
1.136     brouard   424:   Revision 1.135  2009/10/29 15:33:14  brouard
                    425:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    426: 
1.135     brouard   427:   Revision 1.134  2009/10/29 13:18:53  brouard
                    428:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    429: 
1.134     brouard   430:   Revision 1.133  2009/07/06 10:21:25  brouard
                    431:   just nforces
                    432: 
1.133     brouard   433:   Revision 1.132  2009/07/06 08:22:05  brouard
                    434:   Many tings
                    435: 
1.132     brouard   436:   Revision 1.131  2009/06/20 16:22:47  brouard
                    437:   Some dimensions resccaled
                    438: 
1.131     brouard   439:   Revision 1.130  2009/05/26 06:44:34  brouard
                    440:   (Module): Max Covariate is now set to 20 instead of 8. A
                    441:   lot of cleaning with variables initialized to 0. Trying to make
                    442:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    443: 
1.130     brouard   444:   Revision 1.129  2007/08/31 13:49:27  lievre
                    445:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    446: 
1.129     lievre    447:   Revision 1.128  2006/06/30 13:02:05  brouard
                    448:   (Module): Clarifications on computing e.j
                    449: 
1.128     brouard   450:   Revision 1.127  2006/04/28 18:11:50  brouard
                    451:   (Module): Yes the sum of survivors was wrong since
                    452:   imach-114 because nhstepm was no more computed in the age
                    453:   loop. Now we define nhstepma in the age loop.
                    454:   (Module): In order to speed up (in case of numerous covariates) we
                    455:   compute health expectancies (without variances) in a first step
                    456:   and then all the health expectancies with variances or standard
                    457:   deviation (needs data from the Hessian matrices) which slows the
                    458:   computation.
                    459:   In the future we should be able to stop the program is only health
                    460:   expectancies and graph are needed without standard deviations.
                    461: 
1.127     brouard   462:   Revision 1.126  2006/04/28 17:23:28  brouard
                    463:   (Module): Yes the sum of survivors was wrong since
                    464:   imach-114 because nhstepm was no more computed in the age
                    465:   loop. Now we define nhstepma in the age loop.
                    466:   Version 0.98h
                    467: 
1.126     brouard   468:   Revision 1.125  2006/04/04 15:20:31  lievre
                    469:   Errors in calculation of health expectancies. Age was not initialized.
                    470:   Forecasting file added.
                    471: 
                    472:   Revision 1.124  2006/03/22 17:13:53  lievre
                    473:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    474:   The log-likelihood is printed in the log file
                    475: 
                    476:   Revision 1.123  2006/03/20 10:52:43  brouard
                    477:   * imach.c (Module): <title> changed, corresponds to .htm file
                    478:   name. <head> headers where missing.
                    479: 
                    480:   * imach.c (Module): Weights can have a decimal point as for
                    481:   English (a comma might work with a correct LC_NUMERIC environment,
                    482:   otherwise the weight is truncated).
                    483:   Modification of warning when the covariates values are not 0 or
                    484:   1.
                    485:   Version 0.98g
                    486: 
                    487:   Revision 1.122  2006/03/20 09:45:41  brouard
                    488:   (Module): Weights can have a decimal point as for
                    489:   English (a comma might work with a correct LC_NUMERIC environment,
                    490:   otherwise the weight is truncated).
                    491:   Modification of warning when the covariates values are not 0 or
                    492:   1.
                    493:   Version 0.98g
                    494: 
                    495:   Revision 1.121  2006/03/16 17:45:01  lievre
                    496:   * imach.c (Module): Comments concerning covariates added
                    497: 
                    498:   * imach.c (Module): refinements in the computation of lli if
                    499:   status=-2 in order to have more reliable computation if stepm is
                    500:   not 1 month. Version 0.98f
                    501: 
                    502:   Revision 1.120  2006/03/16 15:10:38  lievre
                    503:   (Module): refinements in the computation of lli if
                    504:   status=-2 in order to have more reliable computation if stepm is
                    505:   not 1 month. Version 0.98f
                    506: 
                    507:   Revision 1.119  2006/03/15 17:42:26  brouard
                    508:   (Module): Bug if status = -2, the loglikelihood was
                    509:   computed as likelihood omitting the logarithm. Version O.98e
                    510: 
                    511:   Revision 1.118  2006/03/14 18:20:07  brouard
                    512:   (Module): varevsij Comments added explaining the second
                    513:   table of variances if popbased=1 .
                    514:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    515:   (Module): Function pstamp added
                    516:   (Module): Version 0.98d
                    517: 
                    518:   Revision 1.117  2006/03/14 17:16:22  brouard
                    519:   (Module): varevsij Comments added explaining the second
                    520:   table of variances if popbased=1 .
                    521:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    522:   (Module): Function pstamp added
                    523:   (Module): Version 0.98d
                    524: 
                    525:   Revision 1.116  2006/03/06 10:29:27  brouard
                    526:   (Module): Variance-covariance wrong links and
                    527:   varian-covariance of ej. is needed (Saito).
                    528: 
                    529:   Revision 1.115  2006/02/27 12:17:45  brouard
                    530:   (Module): One freematrix added in mlikeli! 0.98c
                    531: 
                    532:   Revision 1.114  2006/02/26 12:57:58  brouard
                    533:   (Module): Some improvements in processing parameter
                    534:   filename with strsep.
                    535: 
                    536:   Revision 1.113  2006/02/24 14:20:24  brouard
                    537:   (Module): Memory leaks checks with valgrind and:
                    538:   datafile was not closed, some imatrix were not freed and on matrix
                    539:   allocation too.
                    540: 
                    541:   Revision 1.112  2006/01/30 09:55:26  brouard
                    542:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    543: 
                    544:   Revision 1.111  2006/01/25 20:38:18  brouard
                    545:   (Module): Lots of cleaning and bugs added (Gompertz)
                    546:   (Module): Comments can be added in data file. Missing date values
                    547:   can be a simple dot '.'.
                    548: 
                    549:   Revision 1.110  2006/01/25 00:51:50  brouard
                    550:   (Module): Lots of cleaning and bugs added (Gompertz)
                    551: 
                    552:   Revision 1.109  2006/01/24 19:37:15  brouard
                    553:   (Module): Comments (lines starting with a #) are allowed in data.
                    554: 
                    555:   Revision 1.108  2006/01/19 18:05:42  lievre
                    556:   Gnuplot problem appeared...
                    557:   To be fixed
                    558: 
                    559:   Revision 1.107  2006/01/19 16:20:37  brouard
                    560:   Test existence of gnuplot in imach path
                    561: 
                    562:   Revision 1.106  2006/01/19 13:24:36  brouard
                    563:   Some cleaning and links added in html output
                    564: 
                    565:   Revision 1.105  2006/01/05 20:23:19  lievre
                    566:   *** empty log message ***
                    567: 
                    568:   Revision 1.104  2005/09/30 16:11:43  lievre
                    569:   (Module): sump fixed, loop imx fixed, and simplifications.
                    570:   (Module): If the status is missing at the last wave but we know
                    571:   that the person is alive, then we can code his/her status as -2
                    572:   (instead of missing=-1 in earlier versions) and his/her
                    573:   contributions to the likelihood is 1 - Prob of dying from last
                    574:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    575:   the healthy state at last known wave). Version is 0.98
                    576: 
                    577:   Revision 1.103  2005/09/30 15:54:49  lievre
                    578:   (Module): sump fixed, loop imx fixed, and simplifications.
                    579: 
                    580:   Revision 1.102  2004/09/15 17:31:30  brouard
                    581:   Add the possibility to read data file including tab characters.
                    582: 
                    583:   Revision 1.101  2004/09/15 10:38:38  brouard
                    584:   Fix on curr_time
                    585: 
                    586:   Revision 1.100  2004/07/12 18:29:06  brouard
                    587:   Add version for Mac OS X. Just define UNIX in Makefile
                    588: 
                    589:   Revision 1.99  2004/06/05 08:57:40  brouard
                    590:   *** empty log message ***
                    591: 
                    592:   Revision 1.98  2004/05/16 15:05:56  brouard
                    593:   New version 0.97 . First attempt to estimate force of mortality
                    594:   directly from the data i.e. without the need of knowing the health
                    595:   state at each age, but using a Gompertz model: log u =a + b*age .
                    596:   This is the basic analysis of mortality and should be done before any
                    597:   other analysis, in order to test if the mortality estimated from the
                    598:   cross-longitudinal survey is different from the mortality estimated
                    599:   from other sources like vital statistic data.
                    600: 
                    601:   The same imach parameter file can be used but the option for mle should be -3.
                    602: 
1.133     brouard   603:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   604:   former routines in order to include the new code within the former code.
                    605: 
                    606:   The output is very simple: only an estimate of the intercept and of
                    607:   the slope with 95% confident intervals.
                    608: 
                    609:   Current limitations:
                    610:   A) Even if you enter covariates, i.e. with the
                    611:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    612:   B) There is no computation of Life Expectancy nor Life Table.
                    613: 
                    614:   Revision 1.97  2004/02/20 13:25:42  lievre
                    615:   Version 0.96d. Population forecasting command line is (temporarily)
                    616:   suppressed.
                    617: 
                    618:   Revision 1.96  2003/07/15 15:38:55  brouard
                    619:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    620:   rewritten within the same printf. Workaround: many printfs.
                    621: 
                    622:   Revision 1.95  2003/07/08 07:54:34  brouard
                    623:   * imach.c (Repository):
                    624:   (Repository): Using imachwizard code to output a more meaningful covariance
                    625:   matrix (cov(a12,c31) instead of numbers.
                    626: 
                    627:   Revision 1.94  2003/06/27 13:00:02  brouard
                    628:   Just cleaning
                    629: 
                    630:   Revision 1.93  2003/06/25 16:33:55  brouard
                    631:   (Module): On windows (cygwin) function asctime_r doesn't
                    632:   exist so I changed back to asctime which exists.
                    633:   (Module): Version 0.96b
                    634: 
                    635:   Revision 1.92  2003/06/25 16:30:45  brouard
                    636:   (Module): On windows (cygwin) function asctime_r doesn't
                    637:   exist so I changed back to asctime which exists.
                    638: 
                    639:   Revision 1.91  2003/06/25 15:30:29  brouard
                    640:   * imach.c (Repository): Duplicated warning errors corrected.
                    641:   (Repository): Elapsed time after each iteration is now output. It
                    642:   helps to forecast when convergence will be reached. Elapsed time
                    643:   is stamped in powell.  We created a new html file for the graphs
                    644:   concerning matrix of covariance. It has extension -cov.htm.
                    645: 
                    646:   Revision 1.90  2003/06/24 12:34:15  brouard
                    647:   (Module): Some bugs corrected for windows. Also, when
                    648:   mle=-1 a template is output in file "or"mypar.txt with the design
                    649:   of the covariance matrix to be input.
                    650: 
                    651:   Revision 1.89  2003/06/24 12:30:52  brouard
                    652:   (Module): Some bugs corrected for windows. Also, when
                    653:   mle=-1 a template is output in file "or"mypar.txt with the design
                    654:   of the covariance matrix to be input.
                    655: 
                    656:   Revision 1.88  2003/06/23 17:54:56  brouard
                    657:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    658: 
                    659:   Revision 1.87  2003/06/18 12:26:01  brouard
                    660:   Version 0.96
                    661: 
                    662:   Revision 1.86  2003/06/17 20:04:08  brouard
                    663:   (Module): Change position of html and gnuplot routines and added
                    664:   routine fileappend.
                    665: 
                    666:   Revision 1.85  2003/06/17 13:12:43  brouard
                    667:   * imach.c (Repository): Check when date of death was earlier that
                    668:   current date of interview. It may happen when the death was just
                    669:   prior to the death. In this case, dh was negative and likelihood
                    670:   was wrong (infinity). We still send an "Error" but patch by
                    671:   assuming that the date of death was just one stepm after the
                    672:   interview.
                    673:   (Repository): Because some people have very long ID (first column)
                    674:   we changed int to long in num[] and we added a new lvector for
                    675:   memory allocation. But we also truncated to 8 characters (left
                    676:   truncation)
                    677:   (Repository): No more line truncation errors.
                    678: 
                    679:   Revision 1.84  2003/06/13 21:44:43  brouard
                    680:   * imach.c (Repository): Replace "freqsummary" at a correct
                    681:   place. It differs from routine "prevalence" which may be called
                    682:   many times. Probs is memory consuming and must be used with
                    683:   parcimony.
                    684:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    685: 
                    686:   Revision 1.83  2003/06/10 13:39:11  lievre
                    687:   *** empty log message ***
                    688: 
                    689:   Revision 1.82  2003/06/05 15:57:20  brouard
                    690:   Add log in  imach.c and  fullversion number is now printed.
                    691: 
                    692: */
                    693: /*
                    694:    Interpolated Markov Chain
                    695: 
                    696:   Short summary of the programme:
                    697:   
1.227     brouard   698:   This program computes Healthy Life Expectancies or State-specific
                    699:   (if states aren't health statuses) Expectancies from
                    700:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    701: 
                    702:   -1- a first survey ("cross") where individuals from different ages
                    703:   are interviewed on their health status or degree of disability (in
                    704:   the case of a health survey which is our main interest)
                    705: 
                    706:   -2- at least a second wave of interviews ("longitudinal") which
                    707:   measure each change (if any) in individual health status.  Health
                    708:   expectancies are computed from the time spent in each health state
                    709:   according to a model. More health states you consider, more time is
                    710:   necessary to reach the Maximum Likelihood of the parameters involved
                    711:   in the model.  The simplest model is the multinomial logistic model
                    712:   where pij is the probability to be observed in state j at the second
                    713:   wave conditional to be observed in state i at the first
                    714:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    715:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    716:   have a more complex model than "constant and age", you should modify
                    717:   the program where the markup *Covariates have to be included here
                    718:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   719:   convergence.
                    720: 
                    721:   The advantage of this computer programme, compared to a simple
                    722:   multinomial logistic model, is clear when the delay between waves is not
                    723:   identical for each individual. Also, if a individual missed an
                    724:   intermediate interview, the information is lost, but taken into
                    725:   account using an interpolation or extrapolation.  
                    726: 
                    727:   hPijx is the probability to be observed in state i at age x+h
                    728:   conditional to the observed state i at age x. The delay 'h' can be
                    729:   split into an exact number (nh*stepm) of unobserved intermediate
                    730:   states. This elementary transition (by month, quarter,
                    731:   semester or year) is modelled as a multinomial logistic.  The hPx
                    732:   matrix is simply the matrix product of nh*stepm elementary matrices
                    733:   and the contribution of each individual to the likelihood is simply
                    734:   hPijx.
                    735: 
                    736:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   737:   of the life expectancies. It also computes the period (stable) prevalence.
                    738: 
                    739: Back prevalence and projections:
1.227     brouard   740: 
                    741:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    742:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    743:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    744:    mobilavproj)
                    745: 
                    746:     Computes the back prevalence limit for any combination of
                    747:     covariate values k at any age between ageminpar and agemaxpar and
                    748:     returns it in **bprlim. In the loops,
                    749: 
                    750:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    751:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    752: 
                    753:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   754:    Computes for any combination of covariates k and any age between bage and fage 
                    755:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    756:                        oldm=oldms;savm=savms;
1.227     brouard   757: 
                    758:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);
1.218     brouard   759:      Computes the transition matrix starting at age 'age' over
                    760:      'nhstepm*hstepm*stepm' months (i.e. until
                    761:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   762:      nhstepm*hstepm matrices. 
                    763: 
                    764:      Returns p3mat[i][j][h] after calling
                    765:      p3mat[i][j][h]=matprod2(newm,
                    766:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    767:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    768:      oldm);
1.226     brouard   769: 
                    770: Important routines
                    771: 
                    772: - func (or funcone), computes logit (pij) distinguishing
                    773:   o fixed variables (single or product dummies or quantitative);
                    774:   o varying variables by:
                    775:    (1) wave (single, product dummies, quantitative), 
                    776:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    777:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    778:        % varying dummy (not done) or quantitative (not done);
                    779: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    780:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    781: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    782:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    783:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   784: 
1.226     brouard   785: 
                    786:   
1.133     brouard   787:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    788:            Institut national d'études démographiques, Paris.
1.126     brouard   789:   This software have been partly granted by Euro-REVES, a concerted action
                    790:   from the European Union.
                    791:   It is copyrighted identically to a GNU software product, ie programme and
                    792:   software can be distributed freely for non commercial use. Latest version
                    793:   can be accessed at http://euroreves.ined.fr/imach .
                    794: 
                    795:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    796:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    797:   
                    798:   **********************************************************************/
                    799: /*
                    800:   main
                    801:   read parameterfile
                    802:   read datafile
                    803:   concatwav
                    804:   freqsummary
                    805:   if (mle >= 1)
                    806:     mlikeli
                    807:   print results files
                    808:   if mle==1 
                    809:      computes hessian
                    810:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    811:       begin-prev-date,...
                    812:   open gnuplot file
                    813:   open html file
1.145     brouard   814:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    815:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    816:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    817:     freexexit2 possible for memory heap.
                    818: 
                    819:   h Pij x                         | pij_nom  ficrestpij
                    820:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    821:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    822:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    823: 
                    824:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    825:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    826:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    827:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    828:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    829: 
1.126     brouard   830:   forecasting if prevfcast==1 prevforecast call prevalence()
                    831:   health expectancies
                    832:   Variance-covariance of DFLE
                    833:   prevalence()
                    834:    movingaverage()
                    835:   varevsij() 
                    836:   if popbased==1 varevsij(,popbased)
                    837:   total life expectancies
                    838:   Variance of period (stable) prevalence
                    839:  end
                    840: */
                    841: 
1.187     brouard   842: /* #define DEBUG */
                    843: /* #define DEBUGBRENT */
1.203     brouard   844: /* #define DEBUGLINMIN */
                    845: /* #define DEBUGHESS */
                    846: #define DEBUGHESSIJ
1.224     brouard   847: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   848: #define POWELL /* Instead of NLOPT */
1.224     brouard   849: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   850: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    851: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   852: 
                    853: #include <math.h>
                    854: #include <stdio.h>
                    855: #include <stdlib.h>
                    856: #include <string.h>
1.226     brouard   857: #include <ctype.h>
1.159     brouard   858: 
                    859: #ifdef _WIN32
                    860: #include <io.h>
1.172     brouard   861: #include <windows.h>
                    862: #include <tchar.h>
1.159     brouard   863: #else
1.126     brouard   864: #include <unistd.h>
1.159     brouard   865: #endif
1.126     brouard   866: 
                    867: #include <limits.h>
                    868: #include <sys/types.h>
1.171     brouard   869: 
                    870: #if defined(__GNUC__)
                    871: #include <sys/utsname.h> /* Doesn't work on Windows */
                    872: #endif
                    873: 
1.126     brouard   874: #include <sys/stat.h>
                    875: #include <errno.h>
1.159     brouard   876: /* extern int errno; */
1.126     brouard   877: 
1.157     brouard   878: /* #ifdef LINUX */
                    879: /* #include <time.h> */
                    880: /* #include "timeval.h" */
                    881: /* #else */
                    882: /* #include <sys/time.h> */
                    883: /* #endif */
                    884: 
1.126     brouard   885: #include <time.h>
                    886: 
1.136     brouard   887: #ifdef GSL
                    888: #include <gsl/gsl_errno.h>
                    889: #include <gsl/gsl_multimin.h>
                    890: #endif
                    891: 
1.167     brouard   892: 
1.162     brouard   893: #ifdef NLOPT
                    894: #include <nlopt.h>
                    895: typedef struct {
                    896:   double (* function)(double [] );
                    897: } myfunc_data ;
                    898: #endif
                    899: 
1.126     brouard   900: /* #include <libintl.h> */
                    901: /* #define _(String) gettext (String) */
                    902: 
1.141     brouard   903: #define MAXLINE 1024 /* Was 256. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   904: 
                    905: #define GNUPLOTPROGRAM "gnuplot"
                    906: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    907: #define FILENAMELENGTH 132
                    908: 
                    909: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    910: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    911: 
1.144     brouard   912: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    913: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   914: 
                    915: #define NINTERVMAX 8
1.144     brouard   916: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    917: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    918: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   919: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   920: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    921: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   922: #define MAXN 20000
1.144     brouard   923: #define YEARM 12. /**< Number of months per year */
1.218     brouard   924: /* #define AGESUP 130 */
                    925: #define AGESUP 150
                    926: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard   927: #define AGEBASE 40
1.194     brouard   928: #define AGEOVERFLOW 1.e20
1.164     brouard   929: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard   930: #ifdef _WIN32
                    931: #define DIRSEPARATOR '\\'
                    932: #define CHARSEPARATOR "\\"
                    933: #define ODIRSEPARATOR '/'
                    934: #else
1.126     brouard   935: #define DIRSEPARATOR '/'
                    936: #define CHARSEPARATOR "/"
                    937: #define ODIRSEPARATOR '\\'
                    938: #endif
                    939: 
1.246   ! brouard   940: /* $Id: imach.c,v 1.245 2016/09/02 07:25:01 brouard Exp $ */
1.126     brouard   941: /* $State: Exp $ */
1.196     brouard   942: #include "version.h"
                    943: char version[]=__IMACH_VERSION__;
1.224     brouard   944: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.246   ! brouard   945: char fullversion[]="$Revision: 1.245 $ $Date: 2016/09/02 07:25:01 $"; 
1.126     brouard   946: char strstart[80];
                    947: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard   948: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard   949: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard   950: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                    951: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                    952: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard   953: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                    954: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard   955: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                    956: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                    957: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard   958: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                    959: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard   960: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard   961: int nsd=0; /**< Total number of single dummy variables (output) */
                    962: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard   963: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard   964: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard   965: int ntveff=0; /**< ntveff number of effective time varying variables */
                    966: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard   967: int cptcov=0; /* Working variable */
1.218     brouard   968: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard   969: int npar=NPARMAX;
                    970: int nlstate=2; /* Number of live states */
                    971: int ndeath=1; /* Number of dead states */
1.130     brouard   972: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard   973: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard   974: int popbased=0;
                    975: 
                    976: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard   977: int maxwav=0; /* Maxim number of waves */
                    978: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                    979: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                    980: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard   981:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard   982: int mle=1, weightopt=0;
1.126     brouard   983: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                    984: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                    985: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                    986:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard   987: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard   988: int selected(int kvar); /* Is covariate kvar selected for printing results */
                    989: 
1.130     brouard   990: double jmean=1; /* Mean space between 2 waves */
1.145     brouard   991: double **matprod2(); /* test */
1.126     brouard   992: double **oldm, **newm, **savm; /* Working pointers to matrices */
                    993: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard   994: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                    995: 
1.136     brouard   996: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard   997: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard   998: FILE *ficlog, *ficrespow;
1.130     brouard   999: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1000: double fretone; /* Only one call to likelihood */
1.130     brouard  1001: long ipmx=0; /* Number of contributions */
1.126     brouard  1002: double sw; /* Sum of weights */
                   1003: char filerespow[FILENAMELENGTH];
                   1004: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1005: FILE *ficresilk;
                   1006: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1007: FILE *ficresprobmorprev;
                   1008: FILE *fichtm, *fichtmcov; /* Html File */
                   1009: FILE *ficreseij;
                   1010: char filerese[FILENAMELENGTH];
                   1011: FILE *ficresstdeij;
                   1012: char fileresstde[FILENAMELENGTH];
                   1013: FILE *ficrescveij;
                   1014: char filerescve[FILENAMELENGTH];
                   1015: FILE  *ficresvij;
                   1016: char fileresv[FILENAMELENGTH];
                   1017: FILE  *ficresvpl;
                   1018: char fileresvpl[FILENAMELENGTH];
                   1019: char title[MAXLINE];
1.234     brouard  1020: char model[MAXLINE]; /**< The model line */
1.217     brouard  1021: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1022: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1023: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1024: char command[FILENAMELENGTH];
                   1025: int  outcmd=0;
                   1026: 
1.217     brouard  1027: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1028: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1029: char filelog[FILENAMELENGTH]; /* Log file */
                   1030: char filerest[FILENAMELENGTH];
                   1031: char fileregp[FILENAMELENGTH];
                   1032: char popfile[FILENAMELENGTH];
                   1033: 
                   1034: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1035: 
1.157     brouard  1036: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1037: /* struct timezone tzp; */
                   1038: /* extern int gettimeofday(); */
                   1039: struct tm tml, *gmtime(), *localtime();
                   1040: 
                   1041: extern time_t time();
                   1042: 
                   1043: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1044: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1045: struct tm tm;
                   1046: 
1.126     brouard  1047: char strcurr[80], strfor[80];
                   1048: 
                   1049: char *endptr;
                   1050: long lval;
                   1051: double dval;
                   1052: 
                   1053: #define NR_END 1
                   1054: #define FREE_ARG char*
                   1055: #define FTOL 1.0e-10
                   1056: 
                   1057: #define NRANSI 
1.240     brouard  1058: #define ITMAX 200
                   1059: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1060: 
                   1061: #define TOL 2.0e-4 
                   1062: 
                   1063: #define CGOLD 0.3819660 
                   1064: #define ZEPS 1.0e-10 
                   1065: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1066: 
                   1067: #define GOLD 1.618034 
                   1068: #define GLIMIT 100.0 
                   1069: #define TINY 1.0e-20 
                   1070: 
                   1071: static double maxarg1,maxarg2;
                   1072: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1073: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1074:   
                   1075: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1076: #define rint(a) floor(a+0.5)
1.166     brouard  1077: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1078: #define mytinydouble 1.0e-16
1.166     brouard  1079: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1080: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1081: /* static double dsqrarg; */
                   1082: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1083: static double sqrarg;
                   1084: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1085: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1086: int agegomp= AGEGOMP;
                   1087: 
                   1088: int imx; 
                   1089: int stepm=1;
                   1090: /* Stepm, step in month: minimum step interpolation*/
                   1091: 
                   1092: int estepm;
                   1093: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1094: 
                   1095: int m,nb;
                   1096: long *num;
1.197     brouard  1097: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1098: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1099:                   covariate for which somebody answered excluding 
                   1100:                   undefined. Usually 2: 0 and 1. */
                   1101: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1102:                             covariate for which somebody answered including 
                   1103:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1104: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1105: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1106: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1107: double *ageexmed,*agecens;
                   1108: double dateintmean=0;
                   1109: 
                   1110: double *weight;
                   1111: int **s; /* Status */
1.141     brouard  1112: double *agedc;
1.145     brouard  1113: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1114:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1115:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.225     brouard  1116: double **coqvar; /* Fixed quantitative covariate iqv */
                   1117: double ***cotvar; /* Time varying covariate itv */
                   1118: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1119: double  idx; 
                   1120: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1121: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1122: /*k          1  2   3   4     5    6    7     8    9 */
                   1123: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1124: /* Tndvar[k]    1   2   3               4          5 */
                   1125: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1126: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1127: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1128: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1129: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1130: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1131: /* Tprod[i]=k           4               7            */
                   1132: /* Tage[i]=k                  5               8      */
                   1133: /* */
                   1134: /* Type                    */
                   1135: /* V         1  2  3  4  5 */
                   1136: /*           F  F  V  V  V */
                   1137: /*           D  Q  D  D  Q */
                   1138: /*                         */
                   1139: int *TvarsD;
                   1140: int *TvarsDind;
                   1141: int *TvarsQ;
                   1142: int *TvarsQind;
                   1143: 
1.235     brouard  1144: #define MAXRESULTLINES 10
                   1145: int nresult=0;
                   1146: int TKresult[MAXRESULTLINES];
1.237     brouard  1147: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1148: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1149: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1150: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1151: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1152: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1153: 
1.234     brouard  1154: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1155: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1156: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1157: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1158: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1159: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1160: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1161: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1162: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1163: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1164: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1165: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1166: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1167: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1168: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1169: 
1.230     brouard  1170: int *Tvarsel; /**< Selected covariates for output */
                   1171: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1172: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1173: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1174: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1175: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1176: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1177: int *Tage;
1.227     brouard  1178: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1179: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1180: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1181: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1182: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1183: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1184: int **Tvard;
                   1185: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1186: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1187: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1188:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1189:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1190: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1191: double *lsurv, *lpop, *tpop;
                   1192: 
1.231     brouard  1193: #define FD 1; /* Fixed dummy covariate */
                   1194: #define FQ 2; /* Fixed quantitative covariate */
                   1195: #define FP 3; /* Fixed product covariate */
                   1196: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1197: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1198: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1199: #define VD 10; /* Varying dummy covariate */
                   1200: #define VQ 11; /* Varying quantitative covariate */
                   1201: #define VP 12; /* Varying product covariate */
                   1202: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1203: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1204: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1205: #define APFD 16; /* Age product * fixed dummy covariate */
                   1206: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1207: #define APVD 18; /* Age product * varying dummy covariate */
                   1208: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1209: 
                   1210: #define FTYPE 1; /* Fixed covariate */
                   1211: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1212: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1213: 
                   1214: struct kmodel{
                   1215:        int maintype; /* main type */
                   1216:        int subtype; /* subtype */
                   1217: };
                   1218: struct kmodel modell[NCOVMAX];
                   1219: 
1.143     brouard  1220: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1221: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1222: 
                   1223: /**************** split *************************/
                   1224: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1225: {
                   1226:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1227:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1228:   */ 
                   1229:   char *ss;                            /* pointer */
1.186     brouard  1230:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1231: 
                   1232:   l1 = strlen(path );                  /* length of path */
                   1233:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1234:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1235:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1236:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1237:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1238:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1239:     /* get current working directory */
                   1240:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1241: #ifdef WIN32
                   1242:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1243: #else
                   1244:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1245: #endif
1.126     brouard  1246:       return( GLOCK_ERROR_GETCWD );
                   1247:     }
                   1248:     /* got dirc from getcwd*/
                   1249:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1250:   } else {                             /* strip directory from path */
1.126     brouard  1251:     ss++;                              /* after this, the filename */
                   1252:     l2 = strlen( ss );                 /* length of filename */
                   1253:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1254:     strcpy( name, ss );                /* save file name */
                   1255:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1256:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1257:     printf(" DIRC2 = %s \n",dirc);
                   1258:   }
                   1259:   /* We add a separator at the end of dirc if not exists */
                   1260:   l1 = strlen( dirc );                 /* length of directory */
                   1261:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1262:     dirc[l1] =  DIRSEPARATOR;
                   1263:     dirc[l1+1] = 0; 
                   1264:     printf(" DIRC3 = %s \n",dirc);
                   1265:   }
                   1266:   ss = strrchr( name, '.' );           /* find last / */
                   1267:   if (ss >0){
                   1268:     ss++;
                   1269:     strcpy(ext,ss);                    /* save extension */
                   1270:     l1= strlen( name);
                   1271:     l2= strlen(ss)+1;
                   1272:     strncpy( finame, name, l1-l2);
                   1273:     finame[l1-l2]= 0;
                   1274:   }
                   1275: 
                   1276:   return( 0 );                         /* we're done */
                   1277: }
                   1278: 
                   1279: 
                   1280: /******************************************/
                   1281: 
                   1282: void replace_back_to_slash(char *s, char*t)
                   1283: {
                   1284:   int i;
                   1285:   int lg=0;
                   1286:   i=0;
                   1287:   lg=strlen(t);
                   1288:   for(i=0; i<= lg; i++) {
                   1289:     (s[i] = t[i]);
                   1290:     if (t[i]== '\\') s[i]='/';
                   1291:   }
                   1292: }
                   1293: 
1.132     brouard  1294: char *trimbb(char *out, char *in)
1.137     brouard  1295: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1296:   char *s;
                   1297:   s=out;
                   1298:   while (*in != '\0'){
1.137     brouard  1299:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1300:       in++;
                   1301:     }
                   1302:     *out++ = *in++;
                   1303:   }
                   1304:   *out='\0';
                   1305:   return s;
                   1306: }
                   1307: 
1.187     brouard  1308: /* char *substrchaine(char *out, char *in, char *chain) */
                   1309: /* { */
                   1310: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1311: /*   char *s, *t; */
                   1312: /*   t=in;s=out; */
                   1313: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1314: /*     *out++ = *in++; */
                   1315: /*   } */
                   1316: 
                   1317: /*   /\* *in matches *chain *\/ */
                   1318: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1319: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1320: /*   } */
                   1321: /*   in--; chain--; */
                   1322: /*   while ( (*in != '\0')){ */
                   1323: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1324: /*     *out++ = *in++; */
                   1325: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1326: /*   } */
                   1327: /*   *out='\0'; */
                   1328: /*   out=s; */
                   1329: /*   return out; */
                   1330: /* } */
                   1331: char *substrchaine(char *out, char *in, char *chain)
                   1332: {
                   1333:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1334:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1335: 
                   1336:   char *strloc;
                   1337: 
                   1338:   strcpy (out, in); 
                   1339:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1340:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1341:   if(strloc != NULL){ 
                   1342:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1343:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1344:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1345:   }
                   1346:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1347:   return out;
                   1348: }
                   1349: 
                   1350: 
1.145     brouard  1351: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1352: {
1.187     brouard  1353:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1354:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1355:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1356:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1357:   */
1.160     brouard  1358:   char *s, *t;
1.145     brouard  1359:   t=in;s=in;
                   1360:   while ((*in != occ) && (*in != '\0')){
                   1361:     *alocc++ = *in++;
                   1362:   }
                   1363:   if( *in == occ){
                   1364:     *(alocc)='\0';
                   1365:     s=++in;
                   1366:   }
                   1367:  
                   1368:   if (s == t) {/* occ not found */
                   1369:     *(alocc-(in-s))='\0';
                   1370:     in=s;
                   1371:   }
                   1372:   while ( *in != '\0'){
                   1373:     *blocc++ = *in++;
                   1374:   }
                   1375: 
                   1376:   *blocc='\0';
                   1377:   return t;
                   1378: }
1.137     brouard  1379: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1380: {
1.187     brouard  1381:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1382:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1383:      gives blocc="abcdef2ghi" and alocc="j".
                   1384:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1385:   */
                   1386:   char *s, *t;
                   1387:   t=in;s=in;
                   1388:   while (*in != '\0'){
                   1389:     while( *in == occ){
                   1390:       *blocc++ = *in++;
                   1391:       s=in;
                   1392:     }
                   1393:     *blocc++ = *in++;
                   1394:   }
                   1395:   if (s == t) /* occ not found */
                   1396:     *(blocc-(in-s))='\0';
                   1397:   else
                   1398:     *(blocc-(in-s)-1)='\0';
                   1399:   in=s;
                   1400:   while ( *in != '\0'){
                   1401:     *alocc++ = *in++;
                   1402:   }
                   1403: 
                   1404:   *alocc='\0';
                   1405:   return s;
                   1406: }
                   1407: 
1.126     brouard  1408: int nbocc(char *s, char occ)
                   1409: {
                   1410:   int i,j=0;
                   1411:   int lg=20;
                   1412:   i=0;
                   1413:   lg=strlen(s);
                   1414:   for(i=0; i<= lg; i++) {
1.234     brouard  1415:     if  (s[i] == occ ) j++;
1.126     brouard  1416:   }
                   1417:   return j;
                   1418: }
                   1419: 
1.137     brouard  1420: /* void cutv(char *u,char *v, char*t, char occ) */
                   1421: /* { */
                   1422: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1423: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1424: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1425: /*   int i,lg,j,p=0; */
                   1426: /*   i=0; */
                   1427: /*   lg=strlen(t); */
                   1428: /*   for(j=0; j<=lg-1; j++) { */
                   1429: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1430: /*   } */
1.126     brouard  1431: 
1.137     brouard  1432: /*   for(j=0; j<p; j++) { */
                   1433: /*     (u[j] = t[j]); */
                   1434: /*   } */
                   1435: /*      u[p]='\0'; */
1.126     brouard  1436: 
1.137     brouard  1437: /*    for(j=0; j<= lg; j++) { */
                   1438: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1439: /*   } */
                   1440: /* } */
1.126     brouard  1441: 
1.160     brouard  1442: #ifdef _WIN32
                   1443: char * strsep(char **pp, const char *delim)
                   1444: {
                   1445:   char *p, *q;
                   1446:          
                   1447:   if ((p = *pp) == NULL)
                   1448:     return 0;
                   1449:   if ((q = strpbrk (p, delim)) != NULL)
                   1450:   {
                   1451:     *pp = q + 1;
                   1452:     *q = '\0';
                   1453:   }
                   1454:   else
                   1455:     *pp = 0;
                   1456:   return p;
                   1457: }
                   1458: #endif
                   1459: 
1.126     brouard  1460: /********************** nrerror ********************/
                   1461: 
                   1462: void nrerror(char error_text[])
                   1463: {
                   1464:   fprintf(stderr,"ERREUR ...\n");
                   1465:   fprintf(stderr,"%s\n",error_text);
                   1466:   exit(EXIT_FAILURE);
                   1467: }
                   1468: /*********************** vector *******************/
                   1469: double *vector(int nl, int nh)
                   1470: {
                   1471:   double *v;
                   1472:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1473:   if (!v) nrerror("allocation failure in vector");
                   1474:   return v-nl+NR_END;
                   1475: }
                   1476: 
                   1477: /************************ free vector ******************/
                   1478: void free_vector(double*v, int nl, int nh)
                   1479: {
                   1480:   free((FREE_ARG)(v+nl-NR_END));
                   1481: }
                   1482: 
                   1483: /************************ivector *******************************/
                   1484: int *ivector(long nl,long nh)
                   1485: {
                   1486:   int *v;
                   1487:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1488:   if (!v) nrerror("allocation failure in ivector");
                   1489:   return v-nl+NR_END;
                   1490: }
                   1491: 
                   1492: /******************free ivector **************************/
                   1493: void free_ivector(int *v, long nl, long nh)
                   1494: {
                   1495:   free((FREE_ARG)(v+nl-NR_END));
                   1496: }
                   1497: 
                   1498: /************************lvector *******************************/
                   1499: long *lvector(long nl,long nh)
                   1500: {
                   1501:   long *v;
                   1502:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1503:   if (!v) nrerror("allocation failure in ivector");
                   1504:   return v-nl+NR_END;
                   1505: }
                   1506: 
                   1507: /******************free lvector **************************/
                   1508: void free_lvector(long *v, long nl, long nh)
                   1509: {
                   1510:   free((FREE_ARG)(v+nl-NR_END));
                   1511: }
                   1512: 
                   1513: /******************* imatrix *******************************/
                   1514: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1515:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1516: { 
                   1517:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1518:   int **m; 
                   1519:   
                   1520:   /* allocate pointers to rows */ 
                   1521:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1522:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1523:   m += NR_END; 
                   1524:   m -= nrl; 
                   1525:   
                   1526:   
                   1527:   /* allocate rows and set pointers to them */ 
                   1528:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1529:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1530:   m[nrl] += NR_END; 
                   1531:   m[nrl] -= ncl; 
                   1532:   
                   1533:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1534:   
                   1535:   /* return pointer to array of pointers to rows */ 
                   1536:   return m; 
                   1537: } 
                   1538: 
                   1539: /****************** free_imatrix *************************/
                   1540: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1541:       int **m;
                   1542:       long nch,ncl,nrh,nrl; 
                   1543:      /* free an int matrix allocated by imatrix() */ 
                   1544: { 
                   1545:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1546:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1547: } 
                   1548: 
                   1549: /******************* matrix *******************************/
                   1550: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1551: {
                   1552:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1553:   double **m;
                   1554: 
                   1555:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1556:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1557:   m += NR_END;
                   1558:   m -= nrl;
                   1559: 
                   1560:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1561:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1562:   m[nrl] += NR_END;
                   1563:   m[nrl] -= ncl;
                   1564: 
                   1565:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1566:   return m;
1.145     brouard  1567:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1568: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1569: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1570:    */
                   1571: }
                   1572: 
                   1573: /*************************free matrix ************************/
                   1574: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1575: {
                   1576:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1577:   free((FREE_ARG)(m+nrl-NR_END));
                   1578: }
                   1579: 
                   1580: /******************* ma3x *******************************/
                   1581: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1582: {
                   1583:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1584:   double ***m;
                   1585: 
                   1586:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1587:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1588:   m += NR_END;
                   1589:   m -= nrl;
                   1590: 
                   1591:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1592:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1593:   m[nrl] += NR_END;
                   1594:   m[nrl] -= ncl;
                   1595: 
                   1596:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1597: 
                   1598:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1599:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1600:   m[nrl][ncl] += NR_END;
                   1601:   m[nrl][ncl] -= nll;
                   1602:   for (j=ncl+1; j<=nch; j++) 
                   1603:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1604:   
                   1605:   for (i=nrl+1; i<=nrh; i++) {
                   1606:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1607:     for (j=ncl+1; j<=nch; j++) 
                   1608:       m[i][j]=m[i][j-1]+nlay;
                   1609:   }
                   1610:   return m; 
                   1611:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1612:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1613:   */
                   1614: }
                   1615: 
                   1616: /*************************free ma3x ************************/
                   1617: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1618: {
                   1619:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1620:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1621:   free((FREE_ARG)(m+nrl-NR_END));
                   1622: }
                   1623: 
                   1624: /*************** function subdirf ***********/
                   1625: char *subdirf(char fileres[])
                   1626: {
                   1627:   /* Caution optionfilefiname is hidden */
                   1628:   strcpy(tmpout,optionfilefiname);
                   1629:   strcat(tmpout,"/"); /* Add to the right */
                   1630:   strcat(tmpout,fileres);
                   1631:   return tmpout;
                   1632: }
                   1633: 
                   1634: /*************** function subdirf2 ***********/
                   1635: char *subdirf2(char fileres[], char *preop)
                   1636: {
                   1637:   
                   1638:   /* Caution optionfilefiname is hidden */
                   1639:   strcpy(tmpout,optionfilefiname);
                   1640:   strcat(tmpout,"/");
                   1641:   strcat(tmpout,preop);
                   1642:   strcat(tmpout,fileres);
                   1643:   return tmpout;
                   1644: }
                   1645: 
                   1646: /*************** function subdirf3 ***********/
                   1647: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1648: {
                   1649:   
                   1650:   /* Caution optionfilefiname is hidden */
                   1651:   strcpy(tmpout,optionfilefiname);
                   1652:   strcat(tmpout,"/");
                   1653:   strcat(tmpout,preop);
                   1654:   strcat(tmpout,preop2);
                   1655:   strcat(tmpout,fileres);
                   1656:   return tmpout;
                   1657: }
1.213     brouard  1658:  
                   1659: /*************** function subdirfext ***********/
                   1660: char *subdirfext(char fileres[], char *preop, char *postop)
                   1661: {
                   1662:   
                   1663:   strcpy(tmpout,preop);
                   1664:   strcat(tmpout,fileres);
                   1665:   strcat(tmpout,postop);
                   1666:   return tmpout;
                   1667: }
1.126     brouard  1668: 
1.213     brouard  1669: /*************** function subdirfext3 ***********/
                   1670: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1671: {
                   1672:   
                   1673:   /* Caution optionfilefiname is hidden */
                   1674:   strcpy(tmpout,optionfilefiname);
                   1675:   strcat(tmpout,"/");
                   1676:   strcat(tmpout,preop);
                   1677:   strcat(tmpout,fileres);
                   1678:   strcat(tmpout,postop);
                   1679:   return tmpout;
                   1680: }
                   1681:  
1.162     brouard  1682: char *asc_diff_time(long time_sec, char ascdiff[])
                   1683: {
                   1684:   long sec_left, days, hours, minutes;
                   1685:   days = (time_sec) / (60*60*24);
                   1686:   sec_left = (time_sec) % (60*60*24);
                   1687:   hours = (sec_left) / (60*60) ;
                   1688:   sec_left = (sec_left) %(60*60);
                   1689:   minutes = (sec_left) /60;
                   1690:   sec_left = (sec_left) % (60);
                   1691:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1692:   return ascdiff;
                   1693: }
                   1694: 
1.126     brouard  1695: /***************** f1dim *************************/
                   1696: extern int ncom; 
                   1697: extern double *pcom,*xicom;
                   1698: extern double (*nrfunc)(double []); 
                   1699:  
                   1700: double f1dim(double x) 
                   1701: { 
                   1702:   int j; 
                   1703:   double f;
                   1704:   double *xt; 
                   1705:  
                   1706:   xt=vector(1,ncom); 
                   1707:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1708:   f=(*nrfunc)(xt); 
                   1709:   free_vector(xt,1,ncom); 
                   1710:   return f; 
                   1711: } 
                   1712: 
                   1713: /*****************brent *************************/
                   1714: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1715: {
                   1716:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1717:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1718:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1719:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1720:    * returned function value. 
                   1721:   */
1.126     brouard  1722:   int iter; 
                   1723:   double a,b,d,etemp;
1.159     brouard  1724:   double fu=0,fv,fw,fx;
1.164     brouard  1725:   double ftemp=0.;
1.126     brouard  1726:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1727:   double e=0.0; 
                   1728:  
                   1729:   a=(ax < cx ? ax : cx); 
                   1730:   b=(ax > cx ? ax : cx); 
                   1731:   x=w=v=bx; 
                   1732:   fw=fv=fx=(*f)(x); 
                   1733:   for (iter=1;iter<=ITMAX;iter++) { 
                   1734:     xm=0.5*(a+b); 
                   1735:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1736:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1737:     printf(".");fflush(stdout);
                   1738:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1739: #ifdef DEBUGBRENT
1.126     brouard  1740:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1741:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1742:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1743: #endif
                   1744:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1745:       *xmin=x; 
                   1746:       return fx; 
                   1747:     } 
                   1748:     ftemp=fu;
                   1749:     if (fabs(e) > tol1) { 
                   1750:       r=(x-w)*(fx-fv); 
                   1751:       q=(x-v)*(fx-fw); 
                   1752:       p=(x-v)*q-(x-w)*r; 
                   1753:       q=2.0*(q-r); 
                   1754:       if (q > 0.0) p = -p; 
                   1755:       q=fabs(q); 
                   1756:       etemp=e; 
                   1757:       e=d; 
                   1758:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1759:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1760:       else { 
1.224     brouard  1761:                                d=p/q; 
                   1762:                                u=x+d; 
                   1763:                                if (u-a < tol2 || b-u < tol2) 
                   1764:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1765:       } 
                   1766:     } else { 
                   1767:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1768:     } 
                   1769:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1770:     fu=(*f)(u); 
                   1771:     if (fu <= fx) { 
                   1772:       if (u >= x) a=x; else b=x; 
                   1773:       SHFT(v,w,x,u) 
1.183     brouard  1774:       SHFT(fv,fw,fx,fu) 
                   1775:     } else { 
                   1776:       if (u < x) a=u; else b=u; 
                   1777:       if (fu <= fw || w == x) { 
1.224     brouard  1778:                                v=w; 
                   1779:                                w=u; 
                   1780:                                fv=fw; 
                   1781:                                fw=fu; 
1.183     brouard  1782:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1783:                                v=u; 
                   1784:                                fv=fu; 
1.183     brouard  1785:       } 
                   1786:     } 
1.126     brouard  1787:   } 
                   1788:   nrerror("Too many iterations in brent"); 
                   1789:   *xmin=x; 
                   1790:   return fx; 
                   1791: } 
                   1792: 
                   1793: /****************** mnbrak ***********************/
                   1794: 
                   1795: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1796:            double (*func)(double)) 
1.183     brouard  1797: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1798: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1799: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1800: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1801:    */
1.126     brouard  1802:   double ulim,u,r,q, dum;
                   1803:   double fu; 
1.187     brouard  1804: 
                   1805:   double scale=10.;
                   1806:   int iterscale=0;
                   1807: 
                   1808:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1809:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1810: 
                   1811: 
                   1812:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1813:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1814:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1815:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1816:   /* } */
                   1817: 
1.126     brouard  1818:   if (*fb > *fa) { 
                   1819:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1820:     SHFT(dum,*fb,*fa,dum) 
                   1821:   } 
1.126     brouard  1822:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1823:   *fc=(*func)(*cx); 
1.183     brouard  1824: #ifdef DEBUG
1.224     brouard  1825:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1826:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1827: #endif
1.224     brouard  1828:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1829:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1830:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1831:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1832:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1833:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1834:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1835:       fu=(*func)(u); 
1.163     brouard  1836: #ifdef DEBUG
                   1837:       /* f(x)=A(x-u)**2+f(u) */
                   1838:       double A, fparabu; 
                   1839:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1840:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1841:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1842:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1843:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1844:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1845:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1846:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1847: #endif 
1.184     brouard  1848: #ifdef MNBRAKORIGINAL
1.183     brouard  1849: #else
1.191     brouard  1850: /*       if (fu > *fc) { */
                   1851: /* #ifdef DEBUG */
                   1852: /*       printf("mnbrak4  fu > fc \n"); */
                   1853: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1854: /* #endif */
                   1855: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1856: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1857: /*     dum=u; /\* Shifting c and u *\/ */
                   1858: /*     u = *cx; */
                   1859: /*     *cx = dum; */
                   1860: /*     dum = fu; */
                   1861: /*     fu = *fc; */
                   1862: /*     *fc =dum; */
                   1863: /*       } else { /\* end *\/ */
                   1864: /* #ifdef DEBUG */
                   1865: /*       printf("mnbrak3  fu < fc \n"); */
                   1866: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1867: /* #endif */
                   1868: /*     dum=u; /\* Shifting c and u *\/ */
                   1869: /*     u = *cx; */
                   1870: /*     *cx = dum; */
                   1871: /*     dum = fu; */
                   1872: /*     fu = *fc; */
                   1873: /*     *fc =dum; */
                   1874: /*       } */
1.224     brouard  1875: #ifdef DEBUGMNBRAK
                   1876:                 double A, fparabu; 
                   1877:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1878:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1879:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1880:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1881: #endif
1.191     brouard  1882:       dum=u; /* Shifting c and u */
                   1883:       u = *cx;
                   1884:       *cx = dum;
                   1885:       dum = fu;
                   1886:       fu = *fc;
                   1887:       *fc =dum;
1.183     brouard  1888: #endif
1.162     brouard  1889:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1890: #ifdef DEBUG
1.224     brouard  1891:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1892:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1893: #endif
1.126     brouard  1894:       fu=(*func)(u); 
                   1895:       if (fu < *fc) { 
1.183     brouard  1896: #ifdef DEBUG
1.224     brouard  1897:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1898:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1899: #endif
                   1900:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1901:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1902: #ifdef DEBUG
                   1903:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1904: #endif
                   1905:       } 
1.162     brouard  1906:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1907: #ifdef DEBUG
1.224     brouard  1908:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1909:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1910: #endif
1.126     brouard  1911:       u=ulim; 
                   1912:       fu=(*func)(u); 
1.183     brouard  1913:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1914: #ifdef DEBUG
1.224     brouard  1915:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1916:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1917: #endif
1.126     brouard  1918:       u=(*cx)+GOLD*(*cx-*bx); 
                   1919:       fu=(*func)(u); 
1.224     brouard  1920: #ifdef DEBUG
                   1921:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1922:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1923: #endif
1.183     brouard  1924:     } /* end tests */
1.126     brouard  1925:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  1926:     SHFT(*fa,*fb,*fc,fu) 
                   1927: #ifdef DEBUG
1.224     brouard  1928:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   1929:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  1930: #endif
                   1931:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  1932: } 
                   1933: 
                   1934: /*************** linmin ************************/
1.162     brouard  1935: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   1936: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   1937: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   1938: the value of func at the returned location p . This is actually all accomplished by calling the
                   1939: routines mnbrak and brent .*/
1.126     brouard  1940: int ncom; 
                   1941: double *pcom,*xicom;
                   1942: double (*nrfunc)(double []); 
                   1943:  
1.224     brouard  1944: #ifdef LINMINORIGINAL
1.126     brouard  1945: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  1946: #else
                   1947: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   1948: #endif
1.126     brouard  1949: { 
                   1950:   double brent(double ax, double bx, double cx, 
                   1951:               double (*f)(double), double tol, double *xmin); 
                   1952:   double f1dim(double x); 
                   1953:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   1954:              double *fc, double (*func)(double)); 
                   1955:   int j; 
                   1956:   double xx,xmin,bx,ax; 
                   1957:   double fx,fb,fa;
1.187     brouard  1958: 
1.203     brouard  1959: #ifdef LINMINORIGINAL
                   1960: #else
                   1961:   double scale=10., axs, xxs; /* Scale added for infinity */
                   1962: #endif
                   1963:   
1.126     brouard  1964:   ncom=n; 
                   1965:   pcom=vector(1,n); 
                   1966:   xicom=vector(1,n); 
                   1967:   nrfunc=func; 
                   1968:   for (j=1;j<=n;j++) { 
                   1969:     pcom[j]=p[j]; 
1.202     brouard  1970:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  1971:   } 
1.187     brouard  1972: 
1.203     brouard  1973: #ifdef LINMINORIGINAL
                   1974:   xx=1.;
                   1975: #else
                   1976:   axs=0.0;
                   1977:   xxs=1.;
                   1978:   do{
                   1979:     xx= xxs;
                   1980: #endif
1.187     brouard  1981:     ax=0.;
                   1982:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   1983:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   1984:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   1985:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   1986:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   1987:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   1988:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  1989: #ifdef LINMINORIGINAL
                   1990: #else
                   1991:     if (fx != fx){
1.224     brouard  1992:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   1993:                        printf("|");
                   1994:                        fprintf(ficlog,"|");
1.203     brouard  1995: #ifdef DEBUGLINMIN
1.224     brouard  1996:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  1997: #endif
                   1998:     }
1.224     brouard  1999:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2000: #endif
                   2001:   
1.191     brouard  2002: #ifdef DEBUGLINMIN
                   2003:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2004:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2005: #endif
1.224     brouard  2006: #ifdef LINMINORIGINAL
                   2007: #else
                   2008:        if(fb == fx){ /* Flat function in the direction */
                   2009:                xmin=xx;
                   2010:     *flat=1;
                   2011:        }else{
                   2012:     *flat=0;
                   2013: #endif
                   2014:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2015:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2016:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2017:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2018:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2019:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2020: #ifdef DEBUG
1.224     brouard  2021:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2022:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2023: #endif
                   2024: #ifdef LINMINORIGINAL
                   2025: #else
                   2026:                        }
1.126     brouard  2027: #endif
1.191     brouard  2028: #ifdef DEBUGLINMIN
                   2029:   printf("linmin end ");
1.202     brouard  2030:   fprintf(ficlog,"linmin end ");
1.191     brouard  2031: #endif
1.126     brouard  2032:   for (j=1;j<=n;j++) { 
1.203     brouard  2033: #ifdef LINMINORIGINAL
                   2034:     xi[j] *= xmin; 
                   2035: #else
                   2036: #ifdef DEBUGLINMIN
                   2037:     if(xxs <1.0)
                   2038:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2039: #endif
                   2040:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2041: #ifdef DEBUGLINMIN
                   2042:     if(xxs <1.0)
                   2043:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2044: #endif
                   2045: #endif
1.187     brouard  2046:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2047:   } 
1.191     brouard  2048: #ifdef DEBUGLINMIN
1.203     brouard  2049:   printf("\n");
1.191     brouard  2050:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2051:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2052:   for (j=1;j<=n;j++) { 
1.202     brouard  2053:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2054:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2055:     if(j % ncovmodel == 0){
1.191     brouard  2056:       printf("\n");
1.202     brouard  2057:       fprintf(ficlog,"\n");
                   2058:     }
1.191     brouard  2059:   }
1.203     brouard  2060: #else
1.191     brouard  2061: #endif
1.126     brouard  2062:   free_vector(xicom,1,n); 
                   2063:   free_vector(pcom,1,n); 
                   2064: } 
                   2065: 
                   2066: 
                   2067: /*************** powell ************************/
1.162     brouard  2068: /*
                   2069: Minimization of a function func of n variables. Input consists of an initial starting point
                   2070: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2071: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2072: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2073: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2074: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2075:  */
1.224     brouard  2076: #ifdef LINMINORIGINAL
                   2077: #else
                   2078:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2079:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2080: #endif
1.126     brouard  2081: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2082:            double (*func)(double [])) 
                   2083: { 
1.224     brouard  2084: #ifdef LINMINORIGINAL
                   2085:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2086:              double (*func)(double [])); 
1.224     brouard  2087: #else 
1.241     brouard  2088:  void linmin(double p[], double xi[], int n, double *fret,
                   2089:             double (*func)(double []),int *flat); 
1.224     brouard  2090: #endif
1.239     brouard  2091:  int i,ibig,j,jk,k; 
1.126     brouard  2092:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2093:   double directest;
1.126     brouard  2094:   double fp,fptt;
                   2095:   double *xits;
                   2096:   int niterf, itmp;
1.224     brouard  2097: #ifdef LINMINORIGINAL
                   2098: #else
                   2099: 
                   2100:   flatdir=ivector(1,n); 
                   2101:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2102: #endif
1.126     brouard  2103: 
                   2104:   pt=vector(1,n); 
                   2105:   ptt=vector(1,n); 
                   2106:   xit=vector(1,n); 
                   2107:   xits=vector(1,n); 
                   2108:   *fret=(*func)(p); 
                   2109:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2110:   rcurr_time = time(NULL);  
1.126     brouard  2111:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2112:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2113:     ibig=0; 
                   2114:     del=0.0; 
1.157     brouard  2115:     rlast_time=rcurr_time;
                   2116:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2117:     rcurr_time = time(NULL);  
                   2118:     curr_time = *localtime(&rcurr_time);
                   2119:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2120:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2121: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2122:     for (i=1;i<=n;i++) {
1.126     brouard  2123:       fprintf(ficrespow," %.12lf", p[i]);
                   2124:     }
1.239     brouard  2125:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2126:     printf("\n#model=  1      +     age ");
                   2127:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2128:     if(nagesqr==1){
1.241     brouard  2129:        printf("  + age*age  ");
                   2130:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2131:     }
                   2132:     for(j=1;j <=ncovmodel-2;j++){
                   2133:       if(Typevar[j]==0) {
                   2134:        printf("  +      V%d  ",Tvar[j]);
                   2135:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2136:       }else if(Typevar[j]==1) {
                   2137:        printf("  +    V%d*age ",Tvar[j]);
                   2138:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2139:       }else if(Typevar[j]==2) {
                   2140:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2141:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2142:       }
                   2143:     }
1.126     brouard  2144:     printf("\n");
1.239     brouard  2145: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2146: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2147:     fprintf(ficlog,"\n");
1.239     brouard  2148:     for(i=1,jk=1; i <=nlstate; i++){
                   2149:       for(k=1; k <=(nlstate+ndeath); k++){
                   2150:        if (k != i) {
                   2151:          printf("%d%d ",i,k);
                   2152:          fprintf(ficlog,"%d%d ",i,k);
                   2153:          for(j=1; j <=ncovmodel; j++){
                   2154:            printf("%12.7f ",p[jk]);
                   2155:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2156:            jk++; 
                   2157:          }
                   2158:          printf("\n");
                   2159:          fprintf(ficlog,"\n");
                   2160:        }
                   2161:       }
                   2162:     }
1.241     brouard  2163:     if(*iter <=3 && *iter >1){
1.157     brouard  2164:       tml = *localtime(&rcurr_time);
                   2165:       strcpy(strcurr,asctime(&tml));
                   2166:       rforecast_time=rcurr_time; 
1.126     brouard  2167:       itmp = strlen(strcurr);
                   2168:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2169:        strcurr[itmp-1]='\0';
1.162     brouard  2170:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2171:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2172:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2173:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2174:        forecast_time = *localtime(&rforecast_time);
                   2175:        strcpy(strfor,asctime(&forecast_time));
                   2176:        itmp = strlen(strfor);
                   2177:        if(strfor[itmp-1]=='\n')
                   2178:          strfor[itmp-1]='\0';
                   2179:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2180:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2181:       }
                   2182:     }
1.187     brouard  2183:     for (i=1;i<=n;i++) { /* For each direction i */
                   2184:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2185:       fptt=(*fret); 
                   2186: #ifdef DEBUG
1.203     brouard  2187:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2188:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2189: #endif
1.203     brouard  2190:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2191:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2192: #ifdef LINMINORIGINAL
1.188     brouard  2193:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2194: #else
                   2195:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2196:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2197: #endif
                   2198:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2199:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2200:                                /* because that direction will be replaced unless the gain del is small */
                   2201:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2202:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2203:                                /* with the new direction. */
                   2204:                                del=fabs(fptt-(*fret)); 
                   2205:                                ibig=i; 
1.126     brouard  2206:       } 
                   2207: #ifdef DEBUG
                   2208:       printf("%d %.12e",i,(*fret));
                   2209:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2210:       for (j=1;j<=n;j++) {
1.224     brouard  2211:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2212:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2213:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2214:       }
                   2215:       for(j=1;j<=n;j++) {
1.225     brouard  2216:                                printf(" p(%d)=%.12e",j,p[j]);
                   2217:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2218:       }
                   2219:       printf("\n");
                   2220:       fprintf(ficlog,"\n");
                   2221: #endif
1.187     brouard  2222:     } /* end loop on each direction i */
                   2223:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2224:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2225:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2226:       for(j=1;j<=n;j++) {
1.225     brouard  2227:                                if(flatdir[j] >0){
                   2228:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2229:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2230:                                }
                   2231:                                /* printf("\n"); */
                   2232:                                /* fprintf(ficlog,"\n"); */
                   2233:                        }
1.243     brouard  2234:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2235:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2236:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2237:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2238:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2239:       /* decreased of more than 3.84  */
                   2240:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2241:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2242:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2243:                        
1.188     brouard  2244:       /* Starting the program with initial values given by a former maximization will simply change */
                   2245:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2246:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2247:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2248: #ifdef DEBUG
                   2249:       int k[2],l;
                   2250:       k[0]=1;
                   2251:       k[1]=-1;
                   2252:       printf("Max: %.12e",(*func)(p));
                   2253:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2254:       for (j=1;j<=n;j++) {
                   2255:        printf(" %.12e",p[j]);
                   2256:        fprintf(ficlog," %.12e",p[j]);
                   2257:       }
                   2258:       printf("\n");
                   2259:       fprintf(ficlog,"\n");
                   2260:       for(l=0;l<=1;l++) {
                   2261:        for (j=1;j<=n;j++) {
                   2262:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2263:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2264:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2265:        }
                   2266:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2267:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2268:       }
                   2269: #endif
                   2270: 
1.224     brouard  2271: #ifdef LINMINORIGINAL
                   2272: #else
                   2273:       free_ivector(flatdir,1,n); 
                   2274: #endif
1.126     brouard  2275:       free_vector(xit,1,n); 
                   2276:       free_vector(xits,1,n); 
                   2277:       free_vector(ptt,1,n); 
                   2278:       free_vector(pt,1,n); 
                   2279:       return; 
1.192     brouard  2280:     } /* enough precision */ 
1.240     brouard  2281:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2282:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2283:       ptt[j]=2.0*p[j]-pt[j]; 
                   2284:       xit[j]=p[j]-pt[j]; 
                   2285:       pt[j]=p[j]; 
                   2286:     } 
1.181     brouard  2287:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2288: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2289:                if (*iter <=4) {
1.225     brouard  2290: #else
                   2291: #endif
1.224     brouard  2292: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2293: #else
1.161     brouard  2294:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2295: #endif
1.162     brouard  2296:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2297:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2298:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2299:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2300:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2301:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2302:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2303:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2304:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2305:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2306:       /* mu² and del² are equal when f3=f1 */
                   2307:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2308:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2309:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2310:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2311: #ifdef NRCORIGINAL
                   2312:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2313: #else
                   2314:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2315:       t= t- del*SQR(fp-fptt);
1.183     brouard  2316: #endif
1.202     brouard  2317:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2318: #ifdef DEBUG
1.181     brouard  2319:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2320:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2321:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2322:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2323:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2324:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2325:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2326:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2327: #endif
1.183     brouard  2328: #ifdef POWELLORIGINAL
                   2329:       if (t < 0.0) { /* Then we use it for new direction */
                   2330: #else
1.182     brouard  2331:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2332:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2333:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2334:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2335:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2336:       } 
1.181     brouard  2337:       if (directest < 0.0) { /* Then we use it for new direction */
                   2338: #endif
1.191     brouard  2339: #ifdef DEBUGLINMIN
1.234     brouard  2340:        printf("Before linmin in direction P%d-P0\n",n);
                   2341:        for (j=1;j<=n;j++) {
                   2342:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2343:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2344:          if(j % ncovmodel == 0){
                   2345:            printf("\n");
                   2346:            fprintf(ficlog,"\n");
                   2347:          }
                   2348:        }
1.224     brouard  2349: #endif
                   2350: #ifdef LINMINORIGINAL
1.234     brouard  2351:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2352: #else
1.234     brouard  2353:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2354:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2355: #endif
1.234     brouard  2356:        
1.191     brouard  2357: #ifdef DEBUGLINMIN
1.234     brouard  2358:        for (j=1;j<=n;j++) { 
                   2359:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2360:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2361:          if(j % ncovmodel == 0){
                   2362:            printf("\n");
                   2363:            fprintf(ficlog,"\n");
                   2364:          }
                   2365:        }
1.224     brouard  2366: #endif
1.234     brouard  2367:        for (j=1;j<=n;j++) { 
                   2368:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2369:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2370:        }
1.224     brouard  2371: #ifdef LINMINORIGINAL
                   2372: #else
1.234     brouard  2373:        for (j=1, flatd=0;j<=n;j++) {
                   2374:          if(flatdir[j]>0)
                   2375:            flatd++;
                   2376:        }
                   2377:        if(flatd >0){
                   2378:          printf("%d flat directions\n",flatd);
                   2379:          fprintf(ficlog,"%d flat directions\n",flatd);
                   2380:          for (j=1;j<=n;j++) { 
                   2381:            if(flatdir[j]>0){
                   2382:              printf("%d ",j);
                   2383:              fprintf(ficlog,"%d ",j);
                   2384:            }
                   2385:          }
                   2386:          printf("\n");
                   2387:          fprintf(ficlog,"\n");
                   2388:        }
1.191     brouard  2389: #endif
1.234     brouard  2390:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2391:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2392:        
1.126     brouard  2393: #ifdef DEBUG
1.234     brouard  2394:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2395:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2396:        for(j=1;j<=n;j++){
                   2397:          printf(" %lf",xit[j]);
                   2398:          fprintf(ficlog," %lf",xit[j]);
                   2399:        }
                   2400:        printf("\n");
                   2401:        fprintf(ficlog,"\n");
1.126     brouard  2402: #endif
1.192     brouard  2403:       } /* end of t or directest negative */
1.224     brouard  2404: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2405: #else
1.234     brouard  2406:       } /* end if (fptt < fp)  */
1.192     brouard  2407: #endif
1.225     brouard  2408: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2409:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2410: #else
1.224     brouard  2411: #endif
1.234     brouard  2412:                } /* loop iteration */ 
1.126     brouard  2413: } 
1.234     brouard  2414:   
1.126     brouard  2415: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2416:   
1.235     brouard  2417:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2418:   {
1.235     brouard  2419:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2420:        (and selected quantitative values in nres)
                   2421:        by left multiplying the unit
1.234     brouard  2422:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2423:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2424:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2425:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2426:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2427:   /* Initial matrix pimij */
                   2428:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2429:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2430:   /*  0,                   0                  , 1} */
                   2431:   /*
                   2432:    * and after some iteration: */
                   2433:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2434:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2435:   /*  0,                   0                  , 1} */
                   2436:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2437:   /* {0.51571254859325999, 0.4842874514067399, */
                   2438:   /*  0.51326036147820708, 0.48673963852179264} */
                   2439:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2440:     
1.126     brouard  2441:   int i, ii,j,k;
1.209     brouard  2442:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2443:   /* double **matprod2(); */ /* test */
1.218     brouard  2444:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2445:   double **newm;
1.209     brouard  2446:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2447:   int ncvloop=0;
1.169     brouard  2448:   
1.209     brouard  2449:   min=vector(1,nlstate);
                   2450:   max=vector(1,nlstate);
                   2451:   meandiff=vector(1,nlstate);
                   2452: 
1.218     brouard  2453:        /* Starting with matrix unity */
1.126     brouard  2454:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2455:     for (j=1;j<=nlstate+ndeath;j++){
                   2456:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2457:     }
1.169     brouard  2458:   
                   2459:   cov[1]=1.;
                   2460:   
                   2461:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2462:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2463:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2464:     ncvloop++;
1.126     brouard  2465:     newm=savm;
                   2466:     /* Covariates have to be included here again */
1.138     brouard  2467:     cov[2]=agefin;
1.187     brouard  2468:     if(nagesqr==1)
                   2469:       cov[3]= agefin*agefin;;
1.234     brouard  2470:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2471:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2472:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2473:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2474:     }
                   2475:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2476:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2477:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2478:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2479:     }
1.237     brouard  2480:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2481:       if(Dummy[Tvar[Tage[k]]]){
                   2482:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2483:       } else{
1.235     brouard  2484:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2485:       }
1.235     brouard  2486:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2487:     }
1.237     brouard  2488:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2489:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2490:       if(Dummy[Tvard[k][1]==0]){
                   2491:        if(Dummy[Tvard[k][2]==0]){
                   2492:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2493:        }else{
                   2494:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2495:        }
                   2496:       }else{
                   2497:        if(Dummy[Tvard[k][2]==0]){
                   2498:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2499:        }else{
                   2500:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2501:        }
                   2502:       }
1.234     brouard  2503:     }
1.138     brouard  2504:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2505:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2506:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2507:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2508:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2509:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2510:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2511:     
1.126     brouard  2512:     savm=oldm;
                   2513:     oldm=newm;
1.209     brouard  2514: 
                   2515:     for(j=1; j<=nlstate; j++){
                   2516:       max[j]=0.;
                   2517:       min[j]=1.;
                   2518:     }
                   2519:     for(i=1;i<=nlstate;i++){
                   2520:       sumnew=0;
                   2521:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2522:       for(j=1; j<=nlstate; j++){ 
                   2523:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2524:        max[j]=FMAX(max[j],prlim[i][j]);
                   2525:        min[j]=FMIN(min[j],prlim[i][j]);
                   2526:       }
                   2527:     }
                   2528: 
1.126     brouard  2529:     maxmax=0.;
1.209     brouard  2530:     for(j=1; j<=nlstate; j++){
                   2531:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2532:       maxmax=FMAX(maxmax,meandiff[j]);
                   2533:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2534:     } /* j loop */
1.203     brouard  2535:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2536:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2537:     if(maxmax < ftolpl){
1.209     brouard  2538:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2539:       free_vector(min,1,nlstate);
                   2540:       free_vector(max,1,nlstate);
                   2541:       free_vector(meandiff,1,nlstate);
1.126     brouard  2542:       return prlim;
                   2543:     }
1.169     brouard  2544:   } /* age loop */
1.208     brouard  2545:     /* After some age loop it doesn't converge */
1.209     brouard  2546:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2547: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2548:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2549:   free_vector(min,1,nlstate);
                   2550:   free_vector(max,1,nlstate);
                   2551:   free_vector(meandiff,1,nlstate);
1.208     brouard  2552:   
1.169     brouard  2553:   return prlim; /* should not reach here */
1.126     brouard  2554: }
                   2555: 
1.217     brouard  2556: 
                   2557:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2558: 
1.218     brouard  2559:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2560:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2561:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2562: {
1.218     brouard  2563:   /* Computes the prevalence limit in each live state at age x and covariate ij by left multiplying the unit
1.217     brouard  2564:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2565:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2566:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2567:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2568:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2569:   /* Initial matrix pimij */
                   2570:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2571:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2572:   /*  0,                   0                  , 1} */
                   2573:   /*
                   2574:    * and after some iteration: */
                   2575:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2576:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2577:   /*  0,                   0                  , 1} */
                   2578:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2579:   /* {0.51571254859325999, 0.4842874514067399, */
                   2580:   /*  0.51326036147820708, 0.48673963852179264} */
                   2581:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2582: 
                   2583:   int i, ii,j,k;
                   2584:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2585:   /* double **matprod2(); */ /* test */
                   2586:   double **out, cov[NCOVMAX+1], **bmij();
                   2587:   double **newm;
1.218     brouard  2588:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2589:   double        **oldm, **savm;  /* for use */
                   2590: 
1.217     brouard  2591:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2592:   int ncvloop=0;
                   2593:   
                   2594:   min=vector(1,nlstate);
                   2595:   max=vector(1,nlstate);
                   2596:   meandiff=vector(1,nlstate);
                   2597: 
1.218     brouard  2598:        dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2599:        oldm=oldms; savm=savms;
                   2600: 
                   2601:        /* Starting with matrix unity */
                   2602:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   2603:                for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2604:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2605:     }
                   2606:   
                   2607:   cov[1]=1.;
                   2608:   
                   2609:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2610:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2611:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2612:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2613:     ncvloop++;
1.218     brouard  2614:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2615:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2616:     /* Covariates have to be included here again */
                   2617:     cov[2]=agefin;
                   2618:     if(nagesqr==1)
                   2619:       cov[3]= agefin*agefin;;
1.242     brouard  2620:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2621:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2622:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   2623:       /* printf("bprevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   2624:     }
                   2625:     /* for (k=1; k<=cptcovn;k++) { */
                   2626:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2627:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2628:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2629:     /* } */
                   2630:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2631:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2632:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2633:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2634:     }
                   2635:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2636:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2637:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2638:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2639:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2640:       if(Dummy[Tvar[Tage[k]]]){
                   2641:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2642:       } else{
                   2643:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2644:       }
                   2645:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2646:     }
                   2647:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2648:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2649:       if(Dummy[Tvard[k][1]==0]){
                   2650:        if(Dummy[Tvard[k][2]==0]){
                   2651:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2652:        }else{
                   2653:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2654:        }
                   2655:       }else{
                   2656:        if(Dummy[Tvard[k][2]==0]){
                   2657:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2658:        }else{
                   2659:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2660:        }
                   2661:       }
1.217     brouard  2662:     }
                   2663:     
                   2664:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2665:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2666:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2667:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2668:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2669:                /* ij should be linked to the correct index of cov */
                   2670:                /* age and covariate values ij are in 'cov', but we need to pass
                   2671:                 * ij for the observed prevalence at age and status and covariate
                   2672:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2673:                 */
                   2674:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2675:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2676:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.217     brouard  2677:     savm=oldm;
                   2678:     oldm=newm;
                   2679:     for(j=1; j<=nlstate; j++){
                   2680:       max[j]=0.;
                   2681:       min[j]=1.;
                   2682:     }
                   2683:     for(j=1; j<=nlstate; j++){ 
                   2684:       for(i=1;i<=nlstate;i++){
1.234     brouard  2685:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2686:        bprlim[i][j]= newm[i][j];
                   2687:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2688:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2689:       }
                   2690:     }
1.218     brouard  2691:                
1.217     brouard  2692:     maxmax=0.;
                   2693:     for(i=1; i<=nlstate; i++){
                   2694:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2695:       maxmax=FMAX(maxmax,meandiff[i]);
                   2696:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
                   2697:     } /* j loop */
                   2698:     *ncvyear= -( (int)age- (int)agefin);
1.218     brouard  2699:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear);*/
1.217     brouard  2700:     if(maxmax < ftolpl){
1.220     brouard  2701:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2702:       free_vector(min,1,nlstate);
                   2703:       free_vector(max,1,nlstate);
                   2704:       free_vector(meandiff,1,nlstate);
                   2705:       return bprlim;
                   2706:     }
                   2707:   } /* age loop */
                   2708:     /* After some age loop it doesn't converge */
                   2709:   printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
                   2710: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2711:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2712:   free_vector(min,1,nlstate);
                   2713:   free_vector(max,1,nlstate);
                   2714:   free_vector(meandiff,1,nlstate);
                   2715:   
                   2716:   return bprlim; /* should not reach here */
                   2717: }
                   2718: 
1.126     brouard  2719: /*************** transition probabilities ***************/ 
                   2720: 
                   2721: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2722: {
1.138     brouard  2723:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2724:      computes the probability to be observed in state j being in state i by appying the
                   2725:      model to the ncovmodel covariates (including constant and age).
                   2726:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2727:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2728:      ncth covariate in the global vector x is given by the formula:
                   2729:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2730:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2731:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2732:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2733:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2734:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2735:   */
                   2736:   double s1, lnpijopii;
1.126     brouard  2737:   /*double t34;*/
1.164     brouard  2738:   int i,j, nc, ii, jj;
1.126     brouard  2739: 
1.223     brouard  2740:   for(i=1; i<= nlstate; i++){
                   2741:     for(j=1; j<i;j++){
                   2742:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2743:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2744:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2745:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2746:       }
                   2747:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2748:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2749:     }
                   2750:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2751:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2752:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2753:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2754:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2755:       }
                   2756:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2757:     }
                   2758:   }
1.218     brouard  2759:   
1.223     brouard  2760:   for(i=1; i<= nlstate; i++){
                   2761:     s1=0;
                   2762:     for(j=1; j<i; j++){
                   2763:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2764:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2765:     }
                   2766:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2767:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2768:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2769:     }
                   2770:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2771:     ps[i][i]=1./(s1+1.);
                   2772:     /* Computing other pijs */
                   2773:     for(j=1; j<i; j++)
                   2774:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2775:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2776:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2777:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2778:   } /* end i */
1.218     brouard  2779:   
1.223     brouard  2780:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2781:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2782:       ps[ii][jj]=0;
                   2783:       ps[ii][ii]=1;
                   2784:     }
                   2785:   }
1.218     brouard  2786:   
                   2787:   
1.223     brouard  2788:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2789:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2790:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2791:   /*   } */
                   2792:   /*   printf("\n "); */
                   2793:   /* } */
                   2794:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2795:   /*
                   2796:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2797:                goto end;*/
1.223     brouard  2798:   return ps;
1.126     brouard  2799: }
                   2800: 
1.218     brouard  2801: /*************** backward transition probabilities ***************/ 
                   2802: 
                   2803:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2804: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2805:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2806: {
1.222     brouard  2807:   /* Computes the backward probability at age agefin and covariate ij
                   2808:    * and returns in **ps as well as **bmij.
                   2809:    */
1.218     brouard  2810:   int i, ii, j,k;
1.222     brouard  2811:   
                   2812:   double **out, **pmij();
                   2813:   double sumnew=0.;
1.218     brouard  2814:   double agefin;
1.222     brouard  2815:   
                   2816:   double **dnewm, **dsavm, **doldm;
                   2817:   double **bbmij;
                   2818:   
1.218     brouard  2819:   doldm=ddoldms; /* global pointers */
1.222     brouard  2820:   dnewm=ddnewms;
                   2821:   dsavm=ddsavms;
                   2822:   
                   2823:   agefin=cov[2];
                   2824:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
                   2825:      the observed prevalence (with this covariate ij) */
                   2826:   dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate);
                   2827:   /* We do have the matrix Px in savm  and we need pij */
                   2828:   for (j=1;j<=nlstate+ndeath;j++){
                   2829:     sumnew=0.; /* w1 p11 + w2 p21 only on live states */
                   2830:     for (ii=1;ii<=nlstate;ii++){
                   2831:       sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij];
                   2832:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
                   2833:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2834:       if(sumnew >= 1.e-10){
                   2835:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
                   2836:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2837:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
                   2838:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2839:        /* }else */
                   2840:        doldm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2841:       }else{
1.242     brouard  2842:        ;
                   2843:        /* printf("ii=%d, i=%d, doldm=%lf dsavm=%lf, probs=%lf, sumnew=%lf,agefin=%d\n",ii,j,doldm[ii][j],dsavm[ii][j],prevacurrent[(int)agefin][ii][ij],sumnew, (int)agefin); */
1.222     brouard  2844:       }
                   2845:     } /*End ii */
                   2846:   } /* End j, At the end doldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2847:   /* left Product of this diag matrix by dsavm=Px (newm=dsavm*doldm) */
                   2848:   bbmij=matprod2(dnewm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, doldm); /* Bug Valgrind */
                   2849:   /* dsavm=doldm; /\* dsavm is now diag [1/(w_1p1i+w_2 p2i)] but can be overwritten*\/ */
                   2850:   /* doldm=dnewm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2851:   /* dnewm=dsavm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2852:   /* left Product of this matrix by diag matrix of prevalences (savm) */
                   2853:   for (j=1;j<=nlstate+ndeath;j++){
                   2854:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2855:       dsavm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij] : 0.0);
                   2856:     }
                   2857:   } /* End j, At the end oldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2858:   ps=matprod2(doldm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dnewm); /* Bug Valgrind */
                   2859:   /* newm or out is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
                   2860:   /* end bmij */
                   2861:   return ps; 
1.218     brouard  2862: }
1.217     brouard  2863: /*************** transition probabilities ***************/ 
                   2864: 
1.218     brouard  2865: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2866: {
                   2867:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2868:      computes the probability to be observed in state j being in state i by appying the
                   2869:      model to the ncovmodel covariates (including constant and age).
                   2870:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2871:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2872:      ncth covariate in the global vector x is given by the formula:
                   2873:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2874:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2875:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2876:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2877:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2878:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2879:   */
                   2880:   double s1, lnpijopii;
                   2881:   /*double t34;*/
                   2882:   int i,j, nc, ii, jj;
                   2883: 
1.234     brouard  2884:   for(i=1; i<= nlstate; i++){
                   2885:     for(j=1; j<i;j++){
                   2886:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2887:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2888:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2889:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2890:       }
                   2891:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2892:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2893:     }
                   2894:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2895:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2896:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2897:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2898:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2899:       }
                   2900:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2901:     }
                   2902:   }
                   2903:   
                   2904:   for(i=1; i<= nlstate; i++){
                   2905:     s1=0;
                   2906:     for(j=1; j<i; j++){
                   2907:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2908:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2909:     }
                   2910:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2911:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2912:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2913:     }
                   2914:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2915:     ps[i][i]=1./(s1+1.);
                   2916:     /* Computing other pijs */
                   2917:     for(j=1; j<i; j++)
                   2918:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2919:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2920:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2921:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2922:   } /* end i */
                   2923:   
                   2924:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2925:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2926:       ps[ii][jj]=0;
                   2927:       ps[ii][ii]=1;
                   2928:     }
                   2929:   }
                   2930:   /* Added for backcast */ /* Transposed matrix too */
                   2931:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2932:     s1=0.;
                   2933:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   2934:       s1+=ps[ii][jj];
                   2935:     }
                   2936:     for(ii=1; ii<= nlstate; ii++){
                   2937:       ps[ii][jj]=ps[ii][jj]/s1;
                   2938:     }
                   2939:   }
                   2940:   /* Transposition */
                   2941:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2942:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   2943:       s1=ps[ii][jj];
                   2944:       ps[ii][jj]=ps[jj][ii];
                   2945:       ps[jj][ii]=s1;
                   2946:     }
                   2947:   }
                   2948:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2949:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2950:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2951:   /*   } */
                   2952:   /*   printf("\n "); */
                   2953:   /* } */
                   2954:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2955:   /*
                   2956:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   2957:     goto end;*/
                   2958:   return ps;
1.217     brouard  2959: }
                   2960: 
                   2961: 
1.126     brouard  2962: /**************** Product of 2 matrices ******************/
                   2963: 
1.145     brouard  2964: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  2965: {
                   2966:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   2967:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   2968:   /* in, b, out are matrice of pointers which should have been initialized 
                   2969:      before: only the contents of out is modified. The function returns
                   2970:      a pointer to pointers identical to out */
1.145     brouard  2971:   int i, j, k;
1.126     brouard  2972:   for(i=nrl; i<= nrh; i++)
1.145     brouard  2973:     for(k=ncolol; k<=ncoloh; k++){
                   2974:       out[i][k]=0.;
                   2975:       for(j=ncl; j<=nch; j++)
                   2976:        out[i][k] +=in[i][j]*b[j][k];
                   2977:     }
1.126     brouard  2978:   return out;
                   2979: }
                   2980: 
                   2981: 
                   2982: /************* Higher Matrix Product ***************/
                   2983: 
1.235     brouard  2984: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  2985: {
1.218     brouard  2986:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  2987:      'nhstepm*hstepm*stepm' months (i.e. until
                   2988:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   2989:      nhstepm*hstepm matrices. 
                   2990:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   2991:      (typically every 2 years instead of every month which is too big 
                   2992:      for the memory).
                   2993:      Model is determined by parameters x and covariates have to be 
                   2994:      included manually here. 
                   2995: 
                   2996:      */
                   2997: 
                   2998:   int i, j, d, h, k;
1.131     brouard  2999:   double **out, cov[NCOVMAX+1];
1.126     brouard  3000:   double **newm;
1.187     brouard  3001:   double agexact;
1.214     brouard  3002:   double agebegin, ageend;
1.126     brouard  3003: 
                   3004:   /* Hstepm could be zero and should return the unit matrix */
                   3005:   for (i=1;i<=nlstate+ndeath;i++)
                   3006:     for (j=1;j<=nlstate+ndeath;j++){
                   3007:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3008:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3009:     }
                   3010:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3011:   for(h=1; h <=nhstepm; h++){
                   3012:     for(d=1; d <=hstepm; d++){
                   3013:       newm=savm;
                   3014:       /* Covariates have to be included here again */
                   3015:       cov[1]=1.;
1.214     brouard  3016:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3017:       cov[2]=agexact;
                   3018:       if(nagesqr==1)
1.227     brouard  3019:        cov[3]= agexact*agexact;
1.235     brouard  3020:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3021:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3022:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3023:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3024:       }
                   3025:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3026:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3027:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3028:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3029:       }
                   3030:       for (k=1; k<=cptcovage;k++){
                   3031:        if(Dummy[Tvar[Tage[k]]]){
                   3032:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3033:        } else{
                   3034:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3035:        }
                   3036:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3037:       }
                   3038:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3039:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3040:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3041:       }
                   3042:       /* for (k=1; k<=cptcovn;k++)  */
                   3043:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3044:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3045:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3046:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3047:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3048:       
                   3049:       
1.126     brouard  3050:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3051:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3052:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3053:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3054:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3055:       /* if((int)age == 70){ */
                   3056:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3057:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3058:       /*         printf("%d pmmij ",i); */
                   3059:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3060:       /*           printf("%f ",pmmij[i][j]); */
                   3061:       /*         } */
                   3062:       /*         printf(" oldm "); */
                   3063:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3064:       /*           printf("%f ",oldm[i][j]); */
                   3065:       /*         } */
                   3066:       /*         printf("\n"); */
                   3067:       /*       } */
                   3068:       /* } */
1.126     brouard  3069:       savm=oldm;
                   3070:       oldm=newm;
                   3071:     }
                   3072:     for(i=1; i<=nlstate+ndeath; i++)
                   3073:       for(j=1;j<=nlstate+ndeath;j++) {
1.218     brouard  3074:                                po[i][j][h]=newm[i][j];
                   3075:                                /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3076:       }
1.128     brouard  3077:     /*printf("h=%d ",h);*/
1.126     brouard  3078:   } /* end h */
1.218     brouard  3079:        /*     printf("\n H=%d \n",h); */
1.126     brouard  3080:   return po;
                   3081: }
                   3082: 
1.217     brouard  3083: /************* Higher Back Matrix Product ***************/
1.218     brouard  3084: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.222     brouard  3085: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij )
1.217     brouard  3086: {
1.218     brouard  3087:   /* Computes the transition matrix starting at age 'age' over
1.217     brouard  3088:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3089:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3090:      nhstepm*hstepm matrices.
                   3091:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3092:      (typically every 2 years instead of every month which is too big
1.217     brouard  3093:      for the memory).
1.218     brouard  3094:      Model is determined by parameters x and covariates have to be
                   3095:      included manually here.
1.217     brouard  3096: 
1.222     brouard  3097:   */
1.217     brouard  3098: 
                   3099:   int i, j, d, h, k;
                   3100:   double **out, cov[NCOVMAX+1];
                   3101:   double **newm;
                   3102:   double agexact;
                   3103:   double agebegin, ageend;
1.222     brouard  3104:   double **oldm, **savm;
1.217     brouard  3105: 
1.222     brouard  3106:   oldm=oldms;savm=savms;
1.217     brouard  3107:   /* Hstepm could be zero and should return the unit matrix */
                   3108:   for (i=1;i<=nlstate+ndeath;i++)
                   3109:     for (j=1;j<=nlstate+ndeath;j++){
                   3110:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3111:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3112:     }
                   3113:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3114:   for(h=1; h <=nhstepm; h++){
                   3115:     for(d=1; d <=hstepm; d++){
                   3116:       newm=savm;
                   3117:       /* Covariates have to be included here again */
                   3118:       cov[1]=1.;
                   3119:       agexact=age-((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
                   3120:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3121:       cov[2]=agexact;
                   3122:       if(nagesqr==1)
1.222     brouard  3123:        cov[3]= agexact*agexact;
1.218     brouard  3124:       for (k=1; k<=cptcovn;k++)
1.222     brouard  3125:        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   3126:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.217     brouard  3127:       for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
1.222     brouard  3128:        /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   3129:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3130:       /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
1.217     brouard  3131:       for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
1.222     brouard  3132:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3133:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
1.218     brouard  3134:                        
                   3135:                        
1.217     brouard  3136:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3137:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3138:       /* Careful transposed matrix */
1.222     brouard  3139:       /* age is in cov[2] */
1.218     brouard  3140:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3141:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3142:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3143:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3144:       /* if((int)age == 70){ */
                   3145:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3146:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3147:       /*         printf("%d pmmij ",i); */
                   3148:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3149:       /*           printf("%f ",pmmij[i][j]); */
                   3150:       /*         } */
                   3151:       /*         printf(" oldm "); */
                   3152:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3153:       /*           printf("%f ",oldm[i][j]); */
                   3154:       /*         } */
                   3155:       /*         printf("\n"); */
                   3156:       /*       } */
                   3157:       /* } */
                   3158:       savm=oldm;
                   3159:       oldm=newm;
                   3160:     }
                   3161:     for(i=1; i<=nlstate+ndeath; i++)
                   3162:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3163:        po[i][j][h]=newm[i][j];
                   3164:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.217     brouard  3165:       }
                   3166:     /*printf("h=%d ",h);*/
                   3167:   } /* end h */
1.222     brouard  3168:   /*     printf("\n H=%d \n",h); */
1.217     brouard  3169:   return po;
                   3170: }
                   3171: 
                   3172: 
1.162     brouard  3173: #ifdef NLOPT
                   3174:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3175:   double fret;
                   3176:   double *xt;
                   3177:   int j;
                   3178:   myfunc_data *d2 = (myfunc_data *) pd;
                   3179: /* xt = (p1-1); */
                   3180:   xt=vector(1,n); 
                   3181:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3182: 
                   3183:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3184:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3185:   printf("Function = %.12lf ",fret);
                   3186:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3187:   printf("\n");
                   3188:  free_vector(xt,1,n);
                   3189:   return fret;
                   3190: }
                   3191: #endif
1.126     brouard  3192: 
                   3193: /*************** log-likelihood *************/
                   3194: double func( double *x)
                   3195: {
1.226     brouard  3196:   int i, ii, j, k, mi, d, kk;
                   3197:   int ioffset=0;
                   3198:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3199:   double **out;
                   3200:   double lli; /* Individual log likelihood */
                   3201:   int s1, s2;
1.228     brouard  3202:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3203:   double bbh, survp;
                   3204:   long ipmx;
                   3205:   double agexact;
                   3206:   /*extern weight */
                   3207:   /* We are differentiating ll according to initial status */
                   3208:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3209:   /*for(i=1;i<imx;i++) 
                   3210:     printf(" %d\n",s[4][i]);
                   3211:   */
1.162     brouard  3212: 
1.226     brouard  3213:   ++countcallfunc;
1.162     brouard  3214: 
1.226     brouard  3215:   cov[1]=1.;
1.126     brouard  3216: 
1.226     brouard  3217:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3218:   ioffset=0;
1.226     brouard  3219:   if(mle==1){
                   3220:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3221:       /* Computes the values of the ncovmodel covariates of the model
                   3222:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3223:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3224:         to be observed in j being in i according to the model.
                   3225:       */
1.243     brouard  3226:       ioffset=2+nagesqr ;
1.233     brouard  3227:    /* Fixed */
1.234     brouard  3228:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3229:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3230:       }
1.226     brouard  3231:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3232:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3233:         has been calculated etc */
                   3234:       /* For an individual i, wav[i] gives the number of effective waves */
                   3235:       /* We compute the contribution to Likelihood of each effective transition
                   3236:         mw[mi][i] is real wave of the mi th effectve wave */
                   3237:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3238:         s2=s[mw[mi+1][i]][i];
                   3239:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3240:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3241:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3242:       */
                   3243:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3244:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3245:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3246:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3247:        }
                   3248:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3249:          for (j=1;j<=nlstate+ndeath;j++){
                   3250:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3251:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3252:          }
                   3253:        for(d=0; d<dh[mi][i]; d++){
                   3254:          newm=savm;
                   3255:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3256:          cov[2]=agexact;
                   3257:          if(nagesqr==1)
                   3258:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3259:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3260:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3261:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3262:          else
                   3263:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3264:          }
                   3265:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3266:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3267:          savm=oldm;
                   3268:          oldm=newm;
                   3269:        } /* end mult */
                   3270:        
                   3271:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3272:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3273:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3274:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3275:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3276:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3277:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3278:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3279:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3280:                                 * -stepm/2 to stepm/2 .
                   3281:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3282:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3283:                                 */
1.234     brouard  3284:        s1=s[mw[mi][i]][i];
                   3285:        s2=s[mw[mi+1][i]][i];
                   3286:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3287:        /* bias bh is positive if real duration
                   3288:         * is higher than the multiple of stepm and negative otherwise.
                   3289:         */
                   3290:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3291:        if( s2 > nlstate){ 
                   3292:          /* i.e. if s2 is a death state and if the date of death is known 
                   3293:             then the contribution to the likelihood is the probability to 
                   3294:             die between last step unit time and current  step unit time, 
                   3295:             which is also equal to probability to die before dh 
                   3296:             minus probability to die before dh-stepm . 
                   3297:             In version up to 0.92 likelihood was computed
                   3298:             as if date of death was unknown. Death was treated as any other
                   3299:             health state: the date of the interview describes the actual state
                   3300:             and not the date of a change in health state. The former idea was
                   3301:             to consider that at each interview the state was recorded
                   3302:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3303:             introduced the exact date of death then we should have modified
                   3304:             the contribution of an exact death to the likelihood. This new
                   3305:             contribution is smaller and very dependent of the step unit
                   3306:             stepm. It is no more the probability to die between last interview
                   3307:             and month of death but the probability to survive from last
                   3308:             interview up to one month before death multiplied by the
                   3309:             probability to die within a month. Thanks to Chris
                   3310:             Jackson for correcting this bug.  Former versions increased
                   3311:             mortality artificially. The bad side is that we add another loop
                   3312:             which slows down the processing. The difference can be up to 10%
                   3313:             lower mortality.
                   3314:          */
                   3315:          /* If, at the beginning of the maximization mostly, the
                   3316:             cumulative probability or probability to be dead is
                   3317:             constant (ie = 1) over time d, the difference is equal to
                   3318:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3319:             s1 at precedent wave, to be dead a month before current
                   3320:             wave is equal to probability, being at state s1 at
                   3321:             precedent wave, to be dead at mont of the current
                   3322:             wave. Then the observed probability (that this person died)
                   3323:             is null according to current estimated parameter. In fact,
                   3324:             it should be very low but not zero otherwise the log go to
                   3325:             infinity.
                   3326:          */
1.183     brouard  3327: /* #ifdef INFINITYORIGINAL */
                   3328: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3329: /* #else */
                   3330: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3331: /*         lli=log(mytinydouble); */
                   3332: /*       else */
                   3333: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3334: /* #endif */
1.226     brouard  3335:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3336:          
1.226     brouard  3337:        } else if  ( s2==-1 ) { /* alive */
                   3338:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3339:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3340:          /*survp += out[s1][j]; */
                   3341:          lli= log(survp);
                   3342:        }
                   3343:        else if  (s2==-4) { 
                   3344:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3345:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3346:          lli= log(survp); 
                   3347:        } 
                   3348:        else if  (s2==-5) { 
                   3349:          for (j=1,survp=0. ; j<=2; j++)  
                   3350:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3351:          lli= log(survp); 
                   3352:        } 
                   3353:        else{
                   3354:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3355:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3356:        } 
                   3357:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3358:        /*if(lli ==000.0)*/
                   3359:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3360:        ipmx +=1;
                   3361:        sw += weight[i];
                   3362:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3363:        /* if (lli < log(mytinydouble)){ */
                   3364:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3365:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3366:        /* } */
                   3367:       } /* end of wave */
                   3368:     } /* end of individual */
                   3369:   }  else if(mle==2){
                   3370:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3371:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3372:       for(mi=1; mi<= wav[i]-1; mi++){
                   3373:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3374:          for (j=1;j<=nlstate+ndeath;j++){
                   3375:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3376:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3377:          }
                   3378:        for(d=0; d<=dh[mi][i]; d++){
                   3379:          newm=savm;
                   3380:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3381:          cov[2]=agexact;
                   3382:          if(nagesqr==1)
                   3383:            cov[3]= agexact*agexact;
                   3384:          for (kk=1; kk<=cptcovage;kk++) {
                   3385:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3386:          }
                   3387:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3388:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3389:          savm=oldm;
                   3390:          oldm=newm;
                   3391:        } /* end mult */
                   3392:       
                   3393:        s1=s[mw[mi][i]][i];
                   3394:        s2=s[mw[mi+1][i]][i];
                   3395:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3396:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3397:        ipmx +=1;
                   3398:        sw += weight[i];
                   3399:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3400:       } /* end of wave */
                   3401:     } /* end of individual */
                   3402:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3403:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3404:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3405:       for(mi=1; mi<= wav[i]-1; mi++){
                   3406:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3407:          for (j=1;j<=nlstate+ndeath;j++){
                   3408:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3409:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3410:          }
                   3411:        for(d=0; d<dh[mi][i]; d++){
                   3412:          newm=savm;
                   3413:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3414:          cov[2]=agexact;
                   3415:          if(nagesqr==1)
                   3416:            cov[3]= agexact*agexact;
                   3417:          for (kk=1; kk<=cptcovage;kk++) {
                   3418:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3419:          }
                   3420:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3421:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3422:          savm=oldm;
                   3423:          oldm=newm;
                   3424:        } /* end mult */
                   3425:       
                   3426:        s1=s[mw[mi][i]][i];
                   3427:        s2=s[mw[mi+1][i]][i];
                   3428:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3429:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3430:        ipmx +=1;
                   3431:        sw += weight[i];
                   3432:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3433:       } /* end of wave */
                   3434:     } /* end of individual */
                   3435:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3436:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3437:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3438:       for(mi=1; mi<= wav[i]-1; mi++){
                   3439:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3440:          for (j=1;j<=nlstate+ndeath;j++){
                   3441:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3442:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3443:          }
                   3444:        for(d=0; d<dh[mi][i]; d++){
                   3445:          newm=savm;
                   3446:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3447:          cov[2]=agexact;
                   3448:          if(nagesqr==1)
                   3449:            cov[3]= agexact*agexact;
                   3450:          for (kk=1; kk<=cptcovage;kk++) {
                   3451:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3452:          }
1.126     brouard  3453:        
1.226     brouard  3454:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3455:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3456:          savm=oldm;
                   3457:          oldm=newm;
                   3458:        } /* end mult */
                   3459:       
                   3460:        s1=s[mw[mi][i]][i];
                   3461:        s2=s[mw[mi+1][i]][i];
                   3462:        if( s2 > nlstate){ 
                   3463:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3464:        } else if  ( s2==-1 ) { /* alive */
                   3465:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3466:            survp += out[s1][j];
                   3467:          lli= log(survp);
                   3468:        }else{
                   3469:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3470:        }
                   3471:        ipmx +=1;
                   3472:        sw += weight[i];
                   3473:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3474: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3475:       } /* end of wave */
                   3476:     } /* end of individual */
                   3477:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3478:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3479:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3480:       for(mi=1; mi<= wav[i]-1; mi++){
                   3481:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3482:          for (j=1;j<=nlstate+ndeath;j++){
                   3483:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3484:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3485:          }
                   3486:        for(d=0; d<dh[mi][i]; d++){
                   3487:          newm=savm;
                   3488:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3489:          cov[2]=agexact;
                   3490:          if(nagesqr==1)
                   3491:            cov[3]= agexact*agexact;
                   3492:          for (kk=1; kk<=cptcovage;kk++) {
                   3493:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3494:          }
1.126     brouard  3495:        
1.226     brouard  3496:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3497:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3498:          savm=oldm;
                   3499:          oldm=newm;
                   3500:        } /* end mult */
                   3501:       
                   3502:        s1=s[mw[mi][i]][i];
                   3503:        s2=s[mw[mi+1][i]][i];
                   3504:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3505:        ipmx +=1;
                   3506:        sw += weight[i];
                   3507:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3508:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3509:       } /* end of wave */
                   3510:     } /* end of individual */
                   3511:   } /* End of if */
                   3512:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3513:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3514:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3515:   return -l;
1.126     brouard  3516: }
                   3517: 
                   3518: /*************** log-likelihood *************/
                   3519: double funcone( double *x)
                   3520: {
1.228     brouard  3521:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3522:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3523:   int ioffset=0;
1.131     brouard  3524:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3525:   double **out;
                   3526:   double lli; /* Individual log likelihood */
                   3527:   double llt;
                   3528:   int s1, s2;
1.228     brouard  3529:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3530: 
1.126     brouard  3531:   double bbh, survp;
1.187     brouard  3532:   double agexact;
1.214     brouard  3533:   double agebegin, ageend;
1.126     brouard  3534:   /*extern weight */
                   3535:   /* We are differentiating ll according to initial status */
                   3536:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3537:   /*for(i=1;i<imx;i++) 
                   3538:     printf(" %d\n",s[4][i]);
                   3539:   */
                   3540:   cov[1]=1.;
                   3541: 
                   3542:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3543:   ioffset=0;
                   3544:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3545:     /* ioffset=2+nagesqr+cptcovage; */
                   3546:     ioffset=2+nagesqr;
1.232     brouard  3547:     /* Fixed */
1.224     brouard  3548:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3549:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3550:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3551:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3552: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3553: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3554: /*    cov[2+6]=covar[2][i]; V2  */
                   3555: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3556: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3557: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3558: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3559: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3560: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3561:     }
1.232     brouard  3562:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3563:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3564:     /* } */
1.231     brouard  3565:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3566:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3567:     /* } */
1.225     brouard  3568:     
1.233     brouard  3569: 
                   3570:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3571:     /* Wave varying (but not age varying) */
                   3572:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3573:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3574:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3575:       }
1.232     brouard  3576:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3577:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3578:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3579:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3580:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3581:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3582:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3583:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3584:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3585:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3586:       /* } */
1.126     brouard  3587:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3588:        for (j=1;j<=nlstate+ndeath;j++){
                   3589:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3590:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3591:        }
1.214     brouard  3592:       
                   3593:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3594:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3595:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.242     brouard  3596:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3597:          and mw[mi+1][i]. dh depends on stepm.*/
                   3598:        newm=savm;
                   3599:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3600:        cov[2]=agexact;
                   3601:        if(nagesqr==1)
                   3602:          cov[3]= agexact*agexact;
                   3603:        for (kk=1; kk<=cptcovage;kk++) {
                   3604:          if(!FixedV[Tvar[Tage[kk]]])
                   3605:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3606:          else
                   3607:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3608:        }
                   3609:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3610:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3611:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3612:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3613:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3614:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3615:        savm=oldm;
                   3616:        oldm=newm;
1.126     brouard  3617:       } /* end mult */
                   3618:       
                   3619:       s1=s[mw[mi][i]][i];
                   3620:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3621:       /* if(s2==-1){ */
                   3622:       /*       printf(" s1=%d, s2=%d i=%d \n", s1, s2, i); */
                   3623:       /*       /\* exit(1); *\/ */
                   3624:       /* } */
1.126     brouard  3625:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3626:       /* bias is positive if real duration
                   3627:        * is higher than the multiple of stepm and negative otherwise.
                   3628:        */
                   3629:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3630:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3631:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3632:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3633:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3634:        lli= log(survp);
1.126     brouard  3635:       }else if (mle==1){
1.242     brouard  3636:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3637:       } else if(mle==2){
1.242     brouard  3638:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3639:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3640:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3641:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3642:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3643:       } else{  /* mle=0 back to 1 */
1.242     brouard  3644:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3645:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3646:       } /* End of if */
                   3647:       ipmx +=1;
                   3648:       sw += weight[i];
                   3649:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3650:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3651:       if(globpr){
1.246   ! brouard  3652:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3653:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3654:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
                   3655:                2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
                   3656:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3657:          llt +=ll[k]*gipmx/gsw;
                   3658:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3659:        }
                   3660:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3661:       }
1.232     brouard  3662:        } /* end of wave */
                   3663: } /* end of individual */
                   3664: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3665: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3666: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3667: if(globpr==0){ /* First time we count the contributions and weights */
                   3668:        gipmx=ipmx;
                   3669:        gsw=sw;
                   3670: }
                   3671: return -l;
1.126     brouard  3672: }
                   3673: 
                   3674: 
                   3675: /*************** function likelione ***********/
                   3676: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3677: {
                   3678:   /* This routine should help understanding what is done with 
                   3679:      the selection of individuals/waves and
                   3680:      to check the exact contribution to the likelihood.
                   3681:      Plotting could be done.
                   3682:    */
                   3683:   int k;
                   3684: 
                   3685:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3686:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3687:     strcat(fileresilk,fileresu);
1.126     brouard  3688:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3689:       printf("Problem with resultfile: %s\n", fileresilk);
                   3690:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3691:     }
1.214     brouard  3692:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3693:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3694:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3695:     for(k=1; k<=nlstate; k++) 
                   3696:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3697:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3698:   }
                   3699: 
                   3700:   *fretone=(*funcone)(p);
                   3701:   if(*globpri !=0){
                   3702:     fclose(ficresilk);
1.205     brouard  3703:     if (mle ==0)
                   3704:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3705:     else if(mle >=1)
                   3706:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3707:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3708:     
1.208     brouard  3709:       
                   3710:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3711:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3712: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3713:     }
1.207     brouard  3714:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3715: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3716:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3717: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3718:     fflush(fichtm);
1.205     brouard  3719:   }
1.126     brouard  3720:   return;
                   3721: }
                   3722: 
                   3723: 
                   3724: /*********** Maximum Likelihood Estimation ***************/
                   3725: 
                   3726: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3727: {
1.165     brouard  3728:   int i,j, iter=0;
1.126     brouard  3729:   double **xi;
                   3730:   double fret;
                   3731:   double fretone; /* Only one call to likelihood */
                   3732:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3733: 
                   3734: #ifdef NLOPT
                   3735:   int creturn;
                   3736:   nlopt_opt opt;
                   3737:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3738:   double *lb;
                   3739:   double minf; /* the minimum objective value, upon return */
                   3740:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3741:   myfunc_data dinst, *d = &dinst;
                   3742: #endif
                   3743: 
                   3744: 
1.126     brouard  3745:   xi=matrix(1,npar,1,npar);
                   3746:   for (i=1;i<=npar;i++)
                   3747:     for (j=1;j<=npar;j++)
                   3748:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3749:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3750:   strcpy(filerespow,"POW_"); 
1.126     brouard  3751:   strcat(filerespow,fileres);
                   3752:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3753:     printf("Problem with resultfile: %s\n", filerespow);
                   3754:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3755:   }
                   3756:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3757:   for (i=1;i<=nlstate;i++)
                   3758:     for(j=1;j<=nlstate+ndeath;j++)
                   3759:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3760:   fprintf(ficrespow,"\n");
1.162     brouard  3761: #ifdef POWELL
1.126     brouard  3762:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3763: #endif
1.126     brouard  3764: 
1.162     brouard  3765: #ifdef NLOPT
                   3766: #ifdef NEWUOA
                   3767:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3768: #else
                   3769:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3770: #endif
                   3771:   lb=vector(0,npar-1);
                   3772:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3773:   nlopt_set_lower_bounds(opt, lb);
                   3774:   nlopt_set_initial_step1(opt, 0.1);
                   3775:   
                   3776:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3777:   d->function = func;
                   3778:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3779:   nlopt_set_min_objective(opt, myfunc, d);
                   3780:   nlopt_set_xtol_rel(opt, ftol);
                   3781:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3782:     printf("nlopt failed! %d\n",creturn); 
                   3783:   }
                   3784:   else {
                   3785:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3786:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3787:     iter=1; /* not equal */
                   3788:   }
                   3789:   nlopt_destroy(opt);
                   3790: #endif
1.126     brouard  3791:   free_matrix(xi,1,npar,1,npar);
                   3792:   fclose(ficrespow);
1.203     brouard  3793:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3794:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3795:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3796: 
                   3797: }
                   3798: 
                   3799: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3800: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3801: {
                   3802:   double  **a,**y,*x,pd;
1.203     brouard  3803:   /* double **hess; */
1.164     brouard  3804:   int i, j;
1.126     brouard  3805:   int *indx;
                   3806: 
                   3807:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3808:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3809:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3810:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3811:   double gompertz(double p[]);
1.203     brouard  3812:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3813: 
                   3814:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3815:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3816:   for (i=1;i<=npar;i++){
1.203     brouard  3817:     printf("%d-",i);fflush(stdout);
                   3818:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3819:    
                   3820:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3821:     
                   3822:     /*  printf(" %f ",p[i]);
                   3823:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3824:   }
                   3825:   
                   3826:   for (i=1;i<=npar;i++) {
                   3827:     for (j=1;j<=npar;j++)  {
                   3828:       if (j>i) { 
1.203     brouard  3829:        printf(".%d-%d",i,j);fflush(stdout);
                   3830:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3831:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3832:        
                   3833:        hess[j][i]=hess[i][j];    
                   3834:        /*printf(" %lf ",hess[i][j]);*/
                   3835:       }
                   3836:     }
                   3837:   }
                   3838:   printf("\n");
                   3839:   fprintf(ficlog,"\n");
                   3840: 
                   3841:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3842:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3843:   
                   3844:   a=matrix(1,npar,1,npar);
                   3845:   y=matrix(1,npar,1,npar);
                   3846:   x=vector(1,npar);
                   3847:   indx=ivector(1,npar);
                   3848:   for (i=1;i<=npar;i++)
                   3849:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3850:   ludcmp(a,npar,indx,&pd);
                   3851: 
                   3852:   for (j=1;j<=npar;j++) {
                   3853:     for (i=1;i<=npar;i++) x[i]=0;
                   3854:     x[j]=1;
                   3855:     lubksb(a,npar,indx,x);
                   3856:     for (i=1;i<=npar;i++){ 
                   3857:       matcov[i][j]=x[i];
                   3858:     }
                   3859:   }
                   3860: 
                   3861:   printf("\n#Hessian matrix#\n");
                   3862:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   3863:   for (i=1;i<=npar;i++) { 
                   3864:     for (j=1;j<=npar;j++) { 
1.203     brouard  3865:       printf("%.6e ",hess[i][j]);
                   3866:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  3867:     }
                   3868:     printf("\n");
                   3869:     fprintf(ficlog,"\n");
                   3870:   }
                   3871: 
1.203     brouard  3872:   /* printf("\n#Covariance matrix#\n"); */
                   3873:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   3874:   /* for (i=1;i<=npar;i++) {  */
                   3875:   /*   for (j=1;j<=npar;j++) {  */
                   3876:   /*     printf("%.6e ",matcov[i][j]); */
                   3877:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   3878:   /*   } */
                   3879:   /*   printf("\n"); */
                   3880:   /*   fprintf(ficlog,"\n"); */
                   3881:   /* } */
                   3882: 
1.126     brouard  3883:   /* Recompute Inverse */
1.203     brouard  3884:   /* for (i=1;i<=npar;i++) */
                   3885:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   3886:   /* ludcmp(a,npar,indx,&pd); */
                   3887: 
                   3888:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   3889: 
                   3890:   /* for (j=1;j<=npar;j++) { */
                   3891:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   3892:   /*   x[j]=1; */
                   3893:   /*   lubksb(a,npar,indx,x); */
                   3894:   /*   for (i=1;i<=npar;i++){  */
                   3895:   /*     y[i][j]=x[i]; */
                   3896:   /*     printf("%.3e ",y[i][j]); */
                   3897:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   3898:   /*   } */
                   3899:   /*   printf("\n"); */
                   3900:   /*   fprintf(ficlog,"\n"); */
                   3901:   /* } */
                   3902: 
                   3903:   /* Verifying the inverse matrix */
                   3904: #ifdef DEBUGHESS
                   3905:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  3906: 
1.203     brouard  3907:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   3908:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  3909: 
                   3910:   for (j=1;j<=npar;j++) {
                   3911:     for (i=1;i<=npar;i++){ 
1.203     brouard  3912:       printf("%.2f ",y[i][j]);
                   3913:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  3914:     }
                   3915:     printf("\n");
                   3916:     fprintf(ficlog,"\n");
                   3917:   }
1.203     brouard  3918: #endif
1.126     brouard  3919: 
                   3920:   free_matrix(a,1,npar,1,npar);
                   3921:   free_matrix(y,1,npar,1,npar);
                   3922:   free_vector(x,1,npar);
                   3923:   free_ivector(indx,1,npar);
1.203     brouard  3924:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  3925: 
                   3926: 
                   3927: }
                   3928: 
                   3929: /*************** hessian matrix ****************/
                   3930: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  3931: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  3932:   int i;
                   3933:   int l=1, lmax=20;
1.203     brouard  3934:   double k1,k2, res, fx;
1.132     brouard  3935:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  3936:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   3937:   int k=0,kmax=10;
                   3938:   double l1;
                   3939: 
                   3940:   fx=func(x);
                   3941:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  3942:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  3943:     l1=pow(10,l);
                   3944:     delts=delt;
                   3945:     for(k=1 ; k <kmax; k=k+1){
                   3946:       delt = delta*(l1*k);
                   3947:       p2[theta]=x[theta] +delt;
1.145     brouard  3948:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  3949:       p2[theta]=x[theta]-delt;
                   3950:       k2=func(p2)-fx;
                   3951:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  3952:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  3953:       
1.203     brouard  3954: #ifdef DEBUGHESSII
1.126     brouard  3955:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3956:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3957: #endif
                   3958:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   3959:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   3960:        k=kmax;
                   3961:       }
                   3962:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  3963:        k=kmax; l=lmax*10;
1.126     brouard  3964:       }
                   3965:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   3966:        delts=delt;
                   3967:       }
1.203     brouard  3968:     } /* End loop k */
1.126     brouard  3969:   }
                   3970:   delti[theta]=delts;
                   3971:   return res; 
                   3972:   
                   3973: }
                   3974: 
1.203     brouard  3975: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  3976: {
                   3977:   int i;
1.164     brouard  3978:   int l=1, lmax=20;
1.126     brouard  3979:   double k1,k2,k3,k4,res,fx;
1.132     brouard  3980:   double p2[MAXPARM+1];
1.203     brouard  3981:   int k, kmax=1;
                   3982:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  3983: 
                   3984:   int firstime=0;
1.203     brouard  3985:   
1.126     brouard  3986:   fx=func(x);
1.203     brouard  3987:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  3988:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  3989:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   3990:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  3991:     k1=func(p2)-fx;
                   3992:   
1.203     brouard  3993:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   3994:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  3995:     k2=func(p2)-fx;
                   3996:   
1.203     brouard  3997:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   3998:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  3999:     k3=func(p2)-fx;
                   4000:   
1.203     brouard  4001:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4002:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4003:     k4=func(p2)-fx;
1.203     brouard  4004:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4005:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4006:       firstime=1;
1.203     brouard  4007:       kmax=kmax+10;
1.208     brouard  4008:     }
                   4009:     if(kmax >=10 || firstime ==1){
1.246   ! brouard  4010:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
        !          4011:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4012:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4013:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4014:     }
                   4015: #ifdef DEBUGHESSIJ
                   4016:     v1=hess[thetai][thetai];
                   4017:     v2=hess[thetaj][thetaj];
                   4018:     cv12=res;
                   4019:     /* Computing eigen value of Hessian matrix */
                   4020:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4021:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4022:     if ((lc2 <0) || (lc1 <0) ){
                   4023:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4024:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4025:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4026:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4027:     }
1.126     brouard  4028: #endif
                   4029:   }
                   4030:   return res;
                   4031: }
                   4032: 
1.203     brouard  4033:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4034: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4035: /* { */
                   4036: /*   int i; */
                   4037: /*   int l=1, lmax=20; */
                   4038: /*   double k1,k2,k3,k4,res,fx; */
                   4039: /*   double p2[MAXPARM+1]; */
                   4040: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4041: /*   int k=0,kmax=10; */
                   4042: /*   double l1; */
                   4043:   
                   4044: /*   fx=func(x); */
                   4045: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4046: /*     l1=pow(10,l); */
                   4047: /*     delts=delt; */
                   4048: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4049: /*       delt = delti*(l1*k); */
                   4050: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4051: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4052: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4053: /*       k1=func(p2)-fx; */
                   4054:       
                   4055: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4056: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4057: /*       k2=func(p2)-fx; */
                   4058:       
                   4059: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4060: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4061: /*       k3=func(p2)-fx; */
                   4062:       
                   4063: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4064: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4065: /*       k4=func(p2)-fx; */
                   4066: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4067: /* #ifdef DEBUGHESSIJ */
                   4068: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4069: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4070: /* #endif */
                   4071: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4072: /*     k=kmax; */
                   4073: /*       } */
                   4074: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4075: /*     k=kmax; l=lmax*10; */
                   4076: /*       } */
                   4077: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4078: /*     delts=delt; */
                   4079: /*       } */
                   4080: /*     } /\* End loop k *\/ */
                   4081: /*   } */
                   4082: /*   delti[theta]=delts; */
                   4083: /*   return res;  */
                   4084: /* } */
                   4085: 
                   4086: 
1.126     brouard  4087: /************** Inverse of matrix **************/
                   4088: void ludcmp(double **a, int n, int *indx, double *d) 
                   4089: { 
                   4090:   int i,imax,j,k; 
                   4091:   double big,dum,sum,temp; 
                   4092:   double *vv; 
                   4093:  
                   4094:   vv=vector(1,n); 
                   4095:   *d=1.0; 
                   4096:   for (i=1;i<=n;i++) { 
                   4097:     big=0.0; 
                   4098:     for (j=1;j<=n;j++) 
                   4099:       if ((temp=fabs(a[i][j])) > big) big=temp; 
                   4100:     if (big == 0.0) nrerror("Singular matrix in routine ludcmp"); 
                   4101:     vv[i]=1.0/big; 
                   4102:   } 
                   4103:   for (j=1;j<=n;j++) { 
                   4104:     for (i=1;i<j;i++) { 
                   4105:       sum=a[i][j]; 
                   4106:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4107:       a[i][j]=sum; 
                   4108:     } 
                   4109:     big=0.0; 
                   4110:     for (i=j;i<=n;i++) { 
                   4111:       sum=a[i][j]; 
                   4112:       for (k=1;k<j;k++) 
                   4113:        sum -= a[i][k]*a[k][j]; 
                   4114:       a[i][j]=sum; 
                   4115:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4116:        big=dum; 
                   4117:        imax=i; 
                   4118:       } 
                   4119:     } 
                   4120:     if (j != imax) { 
                   4121:       for (k=1;k<=n;k++) { 
                   4122:        dum=a[imax][k]; 
                   4123:        a[imax][k]=a[j][k]; 
                   4124:        a[j][k]=dum; 
                   4125:       } 
                   4126:       *d = -(*d); 
                   4127:       vv[imax]=vv[j]; 
                   4128:     } 
                   4129:     indx[j]=imax; 
                   4130:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4131:     if (j != n) { 
                   4132:       dum=1.0/(a[j][j]); 
                   4133:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4134:     } 
                   4135:   } 
                   4136:   free_vector(vv,1,n);  /* Doesn't work */
                   4137: ;
                   4138: } 
                   4139: 
                   4140: void lubksb(double **a, int n, int *indx, double b[]) 
                   4141: { 
                   4142:   int i,ii=0,ip,j; 
                   4143:   double sum; 
                   4144:  
                   4145:   for (i=1;i<=n;i++) { 
                   4146:     ip=indx[i]; 
                   4147:     sum=b[ip]; 
                   4148:     b[ip]=b[i]; 
                   4149:     if (ii) 
                   4150:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4151:     else if (sum) ii=i; 
                   4152:     b[i]=sum; 
                   4153:   } 
                   4154:   for (i=n;i>=1;i--) { 
                   4155:     sum=b[i]; 
                   4156:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4157:     b[i]=sum/a[i][i]; 
                   4158:   } 
                   4159: } 
                   4160: 
                   4161: void pstamp(FILE *fichier)
                   4162: {
1.196     brouard  4163:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4164: }
                   4165: 
                   4166: /************ Frequencies ********************/
1.226     brouard  4167: void  freqsummary(char fileres[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
                   4168:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4169:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
                   4170: {  /* Some frequencies */
                   4171:   
1.227     brouard  4172:   int i, m, jk, j1, bool, z1,j, k, iv;
1.226     brouard  4173:   int iind=0, iage=0;
                   4174:   int mi; /* Effective wave */
                   4175:   int first;
                   4176:   double ***freq; /* Frequencies */
                   4177:   double *meanq;
                   4178:   double **meanqt;
                   4179:   double *pp, **prop, *posprop, *pospropt;
                   4180:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4181:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4182:   double agebegin, ageend;
                   4183:     
                   4184:   pp=vector(1,nlstate);
                   4185:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+3+AGEMARGE); 
                   4186:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4187:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4188:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4189:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4190:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4191:   strcpy(fileresp,"P_");
                   4192:   strcat(fileresp,fileresu);
                   4193:   /*strcat(fileresphtm,fileresu);*/
                   4194:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4195:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4196:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4197:     exit(0);
                   4198:   }
1.240     brouard  4199:   
1.226     brouard  4200:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4201:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4202:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4203:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4204:     fflush(ficlog);
                   4205:     exit(70); 
                   4206:   }
                   4207:   else{
                   4208:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4209: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4210: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4211:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4212:   }
1.237     brouard  4213:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4214:   
1.226     brouard  4215:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4216:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4217:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4218:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4219:     fflush(ficlog);
                   4220:     exit(70); 
1.240     brouard  4221:   } else{
1.226     brouard  4222:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4223: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4224: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4225:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4226:   }
1.240     brouard  4227:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4228:   
1.226     brouard  4229:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+3+AGEMARGE);
                   4230:   j1=0;
1.126     brouard  4231:   
1.227     brouard  4232:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4233:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4234:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4235:   
1.226     brouard  4236:   first=1;
1.240     brouard  4237:   
1.226     brouard  4238:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4239:      reference=low_education V1=0,V2=0
                   4240:      med_educ                V1=1 V2=0, 
                   4241:      high_educ               V1=0 V2=1
                   4242:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4243:   */
1.240     brouard  4244:   
1.227     brouard  4245:   for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on covariates combination in order of model, excluding quantitatives V4=0, V3=0 for example, fixed or varying covariates */
1.226     brouard  4246:     posproptt=0.;
                   4247:     /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4248:       scanf("%d", i);*/
                   4249:     for (i=-5; i<=nlstate+ndeath; i++)  
                   4250:       for (jk=-5; jk<=nlstate+ndeath; jk++)  
1.240     brouard  4251:        for(m=iagemin; m <= iagemax+3; m++)
                   4252:          freq[i][jk][m]=0;
                   4253:     
1.226     brouard  4254:     for (i=1; i<=nlstate; i++)  {
                   4255:       for(m=iagemin; m <= iagemax+3; m++)
1.240     brouard  4256:        prop[i][m]=0;
1.226     brouard  4257:       posprop[i]=0;
                   4258:       pospropt[i]=0;
                   4259:     }
1.227     brouard  4260:     /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4261:     /*   meanq[z1]+=0.; */
                   4262:     /*   for(m=1;m<=lastpass;m++){ */
                   4263:     /*         meanqt[m][z1]=0.; */
                   4264:     /*   } */
                   4265:     /* } */
1.240     brouard  4266:     
1.226     brouard  4267:     dateintsum=0;
                   4268:     k2cpt=0;
1.227     brouard  4269:     /* For that combination of covariate j1, we count and print the frequencies in one pass */
1.226     brouard  4270:     for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4271:       bool=1;
1.227     brouard  4272:       if(anyvaryingduminmodel==0){ /* If All fixed covariates */
1.234     brouard  4273:        if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
1.227     brouard  4274:          /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4275:          /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4276:          /* } */
1.234     brouard  4277:          for (z1=1; z1<=cptcoveff; z1++) {  
                   4278:            /* if(Tvaraff[z1] ==-20){ */
                   4279:            /*   /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4280:            /* }else  if(Tvaraff[z1] ==-10){ */
                   4281:            /*   /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4282:            /* }else  */
                   4283:            if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){
                   4284:              /* Tests if this individual iind responded to j1 (V4=1 V3=0) */
                   4285:              bool=0;
                   4286:              /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4287:                 bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4288:                 j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4289:              /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4290:            } /* Onlyf fixed */
                   4291:          } /* end z1 */
                   4292:        } /* cptcovn > 0 */
1.227     brouard  4293:       } /* end any */
                   4294:       if (bool==1){ /* We selected an individual iind satisfying combination j1 or all fixed */
1.234     brouard  4295:        /* for(m=firstpass; m<=lastpass; m++){ */
                   4296:        for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4297:          m=mw[mi][iind];
                   4298:          if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4299:            for (z1=1; z1<=cptcoveff; z1++) {
                   4300:              if( Fixed[Tmodelind[z1]]==1){
                   4301:                iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4302:                if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4303:                  bool=0;
                   4304:              }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4305:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4306:                  bool=0;
                   4307:                }
                   4308:              }
                   4309:            }
                   4310:          }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4311:          /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4312:          if(bool==1){
                   4313:            /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4314:               and mw[mi+1][iind]. dh depends on stepm. */
                   4315:            agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4316:            ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4317:            if(m >=firstpass && m <=lastpass){
                   4318:              k2=anint[m][iind]+(mint[m][iind]/12.);
                   4319:              /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4320:              if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4321:              if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4322:              if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4323:                prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4324:              if (m<lastpass) {
                   4325:                /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4326:                /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4327:                if(s[m][iind]==-1)
                   4328:                  printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4329:                freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4330:                /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4331:                freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
                   4332:              }
                   4333:            } /* end if between passes */  
                   4334:            if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99)) {
                   4335:              dateintsum=dateintsum+k2;
                   4336:              k2cpt++;
                   4337:              /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
                   4338:            }
                   4339:          } /* end bool 2 */
                   4340:        } /* end m */
1.226     brouard  4341:       } /* end bool */
                   4342:     } /* end iind = 1 to imx */
                   4343:     /* prop[s][age] is feeded for any initial and valid live state as well as
                   4344:        freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
1.240     brouard  4345:     
                   4346:     
1.226     brouard  4347:     /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
                   4348:     pstamp(ficresp);
1.240     brouard  4349:     if  (cptcoveff>0){
1.226     brouard  4350:       fprintf(ficresp, "\n#********** Variable "); 
                   4351:       fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4352:       fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
1.240     brouard  4353:       fprintf(ficlog, "\n#********** Variable "); 
1.227     brouard  4354:       for (z1=1; z1<=cptcoveff; z1++){
1.240     brouard  4355:        if(DummyV[z1]){
                   4356:          fprintf(ficresp, "V%d (fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4357:          fprintf(ficresphtm, "V%d (fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4358:          fprintf(ficresphtmfr, "V%d (fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4359:          fprintf(ficlog, "V%d (fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4360:        }else{
                   4361:          fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4362:          fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4363:          fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4364:          fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4365:        }
1.226     brouard  4366:       }
                   4367:       fprintf(ficresp, "**********\n#");
                   4368:       fprintf(ficresphtm, "**********</h3>\n");
                   4369:       fprintf(ficresphtmfr, "**********</h3>\n");
                   4370:       fprintf(ficlog, "**********\n");
                   4371:     }
                   4372:     fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
                   4373:     for(i=1; i<=nlstate;i++) {
1.240     brouard  4374:       fprintf(ficresp, " Age Prev(%d)  N(%d)  N  ",i,i);
1.226     brouard  4375:       fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4376:     }
                   4377:     fprintf(ficresp, "\n");
                   4378:     fprintf(ficresphtm, "\n");
1.240     brouard  4379:     
1.226     brouard  4380:     /* Header of frequency table by age */
                   4381:     fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4382:     fprintf(ficresphtmfr,"<th>Age</th> ");
                   4383:     for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4384:       for(m=-1; m <=nlstate+ndeath; m++){
1.234     brouard  4385:        if(jk!=0 && m!=0)
                   4386:          fprintf(ficresphtmfr,"<th>%d%d</th> ",jk,m);
1.226     brouard  4387:       }
                   4388:     }
                   4389:     fprintf(ficresphtmfr, "\n");
1.240     brouard  4390:     
1.226     brouard  4391:     /* For each age */
                   4392:     for(iage=iagemin; iage <= iagemax+3; iage++){
                   4393:       fprintf(ficresphtm,"<tr>");
                   4394:       if(iage==iagemax+1){
1.240     brouard  4395:        fprintf(ficlog,"1");
                   4396:        fprintf(ficresphtmfr,"<tr><th>0</th> ");
1.226     brouard  4397:       }else if(iage==iagemax+2){
1.240     brouard  4398:        fprintf(ficlog,"0");
                   4399:        fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
1.226     brouard  4400:       }else if(iage==iagemax+3){
1.240     brouard  4401:        fprintf(ficlog,"Total");
                   4402:        fprintf(ficresphtmfr,"<tr><th>Total</th> ");
1.226     brouard  4403:       }else{
1.240     brouard  4404:        if(first==1){
                   4405:          first=0;
                   4406:          printf("See log file for details...\n");
                   4407:        }
                   4408:        fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4409:        fprintf(ficlog,"Age %d", iage);
1.226     brouard  4410:       }
                   4411:       for(jk=1; jk <=nlstate ; jk++){
1.240     brouard  4412:        for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
                   4413:          pp[jk] += freq[jk][m][iage]; 
1.226     brouard  4414:       }
                   4415:       for(jk=1; jk <=nlstate ; jk++){
1.240     brouard  4416:        for(m=-1, pos=0; m <=0 ; m++)
                   4417:          pos += freq[jk][m][iage];
                   4418:        if(pp[jk]>=1.e-10){
                   4419:          if(first==1){
                   4420:            printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4421:          }
                   4422:          fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4423:        }else{
                   4424:          if(first==1)
                   4425:            printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
                   4426:          fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
                   4427:        }
1.226     brouard  4428:       }
1.240     brouard  4429:       
1.226     brouard  4430:       for(jk=1; jk <=nlstate ; jk++){ 
1.240     brouard  4431:        /* posprop[jk]=0; */
                   4432:        for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4433:          pp[jk] += freq[jk][m][iage];
1.226     brouard  4434:       }        /* pp[jk] is the total number of transitions starting from state jk and any ending status until this age */
1.240     brouard  4435:       
1.226     brouard  4436:       for(jk=1,pos=0, pospropta=0.; jk <=nlstate ; jk++){
1.240     brouard  4437:        pos += pp[jk]; /* pos is the total number of transitions until this age */
                   4438:        posprop[jk] += prop[jk][iage]; /* prop is the number of transitions from a live state
                   4439:                                          from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4440:        pospropta += prop[jk][iage]; /* prop is the number of transitions from a live state
                   4441:                                        from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
1.226     brouard  4442:       }
                   4443:       for(jk=1; jk <=nlstate ; jk++){
1.240     brouard  4444:        if(pos>=1.e-5){
                   4445:          if(first==1)
                   4446:            printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4447:          fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4448:        }else{
                   4449:          if(first==1)
                   4450:            printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4451:          fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4452:        }
                   4453:        if( iage <= iagemax){
                   4454:          if(pos>=1.e-5){
                   4455:            fprintf(ficresp," %d %.5f %.0f %.0f",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4456:            fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4457:            /*probs[iage][jk][j1]= pp[jk]/pos;*/
                   4458:            /*printf("\niage=%d jk=%d j1=%d %.5f %.0f %.0f %f",iage,jk,j1,pp[jk]/pos, pp[jk],pos,probs[iage][jk][j1]);*/
                   4459:          }
                   4460:          else{
                   4461:            fprintf(ficresp," %d NaNq %.0f %.0f",iage,prop[jk][iage],pospropta);
                   4462:            fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[jk][iage],pospropta);
                   4463:          }
                   4464:        }
                   4465:        pospropt[jk] +=posprop[jk];
1.226     brouard  4466:       } /* end loop jk */
                   4467:       /* pospropt=0.; */
                   4468:       for(jk=-1; jk <=nlstate+ndeath; jk++){
1.240     brouard  4469:        for(m=-1; m <=nlstate+ndeath; m++){
                   4470:          if(freq[jk][m][iage] !=0 ) { /* minimizing output */
                   4471:            if(first==1){
                   4472:              printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4473:            }
                   4474:            fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4475:          }
                   4476:          if(jk!=0 && m!=0)
                   4477:            fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[jk][m][iage]);
                   4478:        }
1.226     brouard  4479:       } /* end loop jk */
                   4480:       posproptt=0.; 
                   4481:       for(jk=1; jk <=nlstate; jk++){
1.240     brouard  4482:        posproptt += pospropt[jk];
1.226     brouard  4483:       }
                   4484:       fprintf(ficresphtmfr,"</tr>\n ");
                   4485:       if(iage <= iagemax){
1.240     brouard  4486:        fprintf(ficresp,"\n");
                   4487:        fprintf(ficresphtm,"</tr>\n");
1.226     brouard  4488:       }
                   4489:       if(first==1)
1.240     brouard  4490:        printf("Others in log...\n");
1.226     brouard  4491:       fprintf(ficlog,"\n");
                   4492:     } /* end loop age iage */
                   4493:     fprintf(ficresphtm,"<tr><th>Tot</th>");
                   4494:     for(jk=1; jk <=nlstate ; jk++){
                   4495:       if(posproptt < 1.e-5){
1.240     brouard  4496:        fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[jk],posproptt);   
1.226     brouard  4497:       }else{
1.240     brouard  4498:        fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[jk]/posproptt,pospropt[jk],posproptt);    
1.226     brouard  4499:       }
                   4500:     }
                   4501:     fprintf(ficresphtm,"</tr>\n");
                   4502:     fprintf(ficresphtm,"</table>\n");
                   4503:     fprintf(ficresphtmfr,"</table>\n");
                   4504:     if(posproptt < 1.e-5){
                   4505:       fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4506:       fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4507:       fprintf(ficres,"\n  This combination (%d) is not valid and no result will be produced\n\n",j1);
                   4508:       invalidvarcomb[j1]=1;
                   4509:     }else{
                   4510:       fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4511:       invalidvarcomb[j1]=0;
                   4512:     }
                   4513:     fprintf(ficresphtmfr,"</table>\n");
                   4514:   } /* end selected combination of covariate j1 */
                   4515:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4516:   
1.226     brouard  4517:   fclose(ficresp);
                   4518:   fclose(ficresphtm);
                   4519:   fclose(ficresphtmfr);
                   4520:   free_vector(meanq,1,nqfveff);
                   4521:   free_matrix(meanqt,1,lastpass,1,nqtveff);
                   4522:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+3+AGEMARGE);
                   4523:   free_vector(pospropt,1,nlstate);
                   4524:   free_vector(posprop,1,nlstate);
                   4525:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+3+AGEMARGE);
                   4526:   free_vector(pp,1,nlstate);
                   4527:   /* End of freqsummary */
                   4528: }
1.126     brouard  4529: 
                   4530: /************ Prevalence ********************/
1.227     brouard  4531: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4532: {  
                   4533:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4534:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4535:      We still use firstpass and lastpass as another selection.
                   4536:   */
1.126     brouard  4537:  
1.227     brouard  4538:   int i, m, jk, j1, bool, z1,j, iv;
                   4539:   int mi; /* Effective wave */
                   4540:   int iage;
                   4541:   double agebegin, ageend;
                   4542: 
                   4543:   double **prop;
                   4544:   double posprop; 
                   4545:   double  y2; /* in fractional years */
                   4546:   int iagemin, iagemax;
                   4547:   int first; /** to stop verbosity which is redirected to log file */
                   4548: 
                   4549:   iagemin= (int) agemin;
                   4550:   iagemax= (int) agemax;
                   4551:   /*pp=vector(1,nlstate);*/
                   4552:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+3+AGEMARGE); 
                   4553:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4554:   j1=0;
1.222     brouard  4555:   
1.227     brouard  4556:   /*j=cptcoveff;*/
                   4557:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4558:   
1.227     brouard  4559:   first=1;
                   4560:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4561:     for (i=1; i<=nlstate; i++)  
                   4562:       for(iage=iagemin-AGEMARGE; iage <= iagemax+3+AGEMARGE; iage++)
                   4563:        prop[i][iage]=0.0;
                   4564:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4565:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4566:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4567:     
                   4568:     for (i=1; i<=imx; i++) { /* Each individual */
                   4569:       bool=1;
                   4570:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4571:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4572:        m=mw[mi][i];
                   4573:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4574:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4575:        for (z1=1; z1<=cptcoveff; z1++){
                   4576:          if( Fixed[Tmodelind[z1]]==1){
                   4577:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4578:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4579:              bool=0;
                   4580:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4581:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4582:              bool=0;
                   4583:            }
                   4584:        }
                   4585:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4586:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4587:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4588:          if(m >=firstpass && m <=lastpass){
                   4589:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4590:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4591:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   4592:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
                   4593:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+3+AGEMARGE){
                   4594:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   4595:                exit(1);
                   4596:              }
                   4597:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   4598:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   4599:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   4600:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   4601:              } /* end valid statuses */ 
                   4602:            } /* end selection of dates */
                   4603:          } /* end selection of waves */
                   4604:        } /* end bool */
                   4605:       } /* end wave */
                   4606:     } /* end individual */
                   4607:     for(i=iagemin; i <= iagemax+3; i++){  
                   4608:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   4609:        posprop += prop[jk][i]; 
                   4610:       } 
                   4611:       
                   4612:       for(jk=1; jk <=nlstate ; jk++){      
                   4613:        if( i <=  iagemax){ 
                   4614:          if(posprop>=1.e-5){ 
                   4615:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   4616:          } else{
                   4617:            if(first==1){
                   4618:              first=0;
                   4619:              printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,j1,probs[i][jk][j1]);
                   4620:            }
                   4621:          }
                   4622:        } 
                   4623:       }/* end jk */ 
                   4624:     }/* end i */ 
1.222     brouard  4625:      /*} *//* end i1 */
1.227     brouard  4626:   } /* end j1 */
1.222     brouard  4627:   
1.227     brouard  4628:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   4629:   /*free_vector(pp,1,nlstate);*/
                   4630:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+3+AGEMARGE);
                   4631: }  /* End of prevalence */
1.126     brouard  4632: 
                   4633: /************* Waves Concatenation ***************/
                   4634: 
                   4635: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   4636: {
                   4637:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   4638:      Death is a valid wave (if date is known).
                   4639:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   4640:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4641:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  4642:   */
1.126     brouard  4643: 
1.224     brouard  4644:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  4645:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   4646:      double sum=0., jmean=0.;*/
1.224     brouard  4647:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  4648:   int j, k=0,jk, ju, jl;
                   4649:   double sum=0.;
                   4650:   first=0;
1.214     brouard  4651:   firstwo=0;
1.217     brouard  4652:   firsthree=0;
1.218     brouard  4653:   firstfour=0;
1.164     brouard  4654:   jmin=100000;
1.126     brouard  4655:   jmax=-1;
                   4656:   jmean=0.;
1.224     brouard  4657: 
                   4658: /* Treating live states */
1.214     brouard  4659:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  4660:     mi=0;  /* First valid wave */
1.227     brouard  4661:     mli=0; /* Last valid wave */
1.126     brouard  4662:     m=firstpass;
1.214     brouard  4663:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  4664:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   4665:        mli=m-1;/* mw[++mi][i]=m-1; */
                   4666:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   4667:        mw[++mi][i]=m;
                   4668:        mli=m;
1.224     brouard  4669:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   4670:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  4671:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  4672:       }
1.227     brouard  4673:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  4674: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  4675:        break;
1.224     brouard  4676: #else
1.227     brouard  4677:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   4678:          if(firsthree == 0){
                   4679:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4680:            firsthree=1;
                   4681:          }
                   4682:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4683:          mw[++mi][i]=m;
                   4684:          mli=m;
                   4685:        }
                   4686:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   4687:          nbwarn++;
                   4688:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   4689:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4690:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4691:          }
                   4692:          break;
                   4693:        }
                   4694:        break;
1.224     brouard  4695: #endif
1.227     brouard  4696:       }/* End m >= lastpass */
1.126     brouard  4697:     }/* end while */
1.224     brouard  4698: 
1.227     brouard  4699:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  4700:     /* After last pass */
1.224     brouard  4701: /* Treating death states */
1.214     brouard  4702:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  4703:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   4704:       /* } */
1.126     brouard  4705:       mi++;    /* Death is another wave */
                   4706:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  4707:       /* Only death is a correct wave */
1.126     brouard  4708:       mw[mi][i]=m;
1.224     brouard  4709:     }
                   4710: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.227     brouard  4711:     else if ((int) andc[i] != 9999) { /* Status is negative. A death occured after lastpass, we can't take it into account because of potential bias */
1.216     brouard  4712:       /* m++; */
                   4713:       /* mi++; */
                   4714:       /* s[m][i]=nlstate+1;  /\* We are setting the status to the last of non live state *\/ */
                   4715:       /* mw[mi][i]=m; */
1.218     brouard  4716:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  4717:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   4718:          nbwarn++;
                   4719:          if(firstfiv==0){
                   4720:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4721:            firstfiv=1;
                   4722:          }else{
                   4723:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4724:          }
                   4725:        }else{ /* Death occured afer last wave potential bias */
                   4726:          nberr++;
                   4727:          if(firstwo==0){
                   4728:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4729:            firstwo=1;
                   4730:          }
                   4731:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4732:        }
1.218     brouard  4733:       }else{ /* end date of interview is known */
1.227     brouard  4734:        /* death is known but not confirmed by death status at any wave */
                   4735:        if(firstfour==0){
                   4736:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4737:          firstfour=1;
                   4738:        }
                   4739:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  4740:       }
1.224     brouard  4741:     } /* end if date of death is known */
                   4742: #endif
                   4743:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   4744:     /* wav[i]=mw[mi][i]; */
1.126     brouard  4745:     if(mi==0){
                   4746:       nbwarn++;
                   4747:       if(first==0){
1.227     brouard  4748:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   4749:        first=1;
1.126     brouard  4750:       }
                   4751:       if(first==1){
1.227     brouard  4752:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  4753:       }
                   4754:     } /* end mi==0 */
                   4755:   } /* End individuals */
1.214     brouard  4756:   /* wav and mw are no more changed */
1.223     brouard  4757:        
1.214     brouard  4758:   
1.126     brouard  4759:   for(i=1; i<=imx; i++){
                   4760:     for(mi=1; mi<wav[i];mi++){
                   4761:       if (stepm <=0)
1.227     brouard  4762:        dh[mi][i]=1;
1.126     brouard  4763:       else{
1.227     brouard  4764:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death */
                   4765:          if (agedc[i] < 2*AGESUP) {
                   4766:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   4767:            if(j==0) j=1;  /* Survives at least one month after exam */
                   4768:            else if(j<0){
                   4769:              nberr++;
                   4770:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4771:              j=1; /* Temporary Dangerous patch */
                   4772:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   4773:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4774:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   4775:            }
                   4776:            k=k+1;
                   4777:            if (j >= jmax){
                   4778:              jmax=j;
                   4779:              ijmax=i;
                   4780:            }
                   4781:            if (j <= jmin){
                   4782:              jmin=j;
                   4783:              ijmin=i;
                   4784:            }
                   4785:            sum=sum+j;
                   4786:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   4787:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   4788:          }
                   4789:        }
                   4790:        else{
                   4791:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  4792: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  4793:                                        
1.227     brouard  4794:          k=k+1;
                   4795:          if (j >= jmax) {
                   4796:            jmax=j;
                   4797:            ijmax=i;
                   4798:          }
                   4799:          else if (j <= jmin){
                   4800:            jmin=j;
                   4801:            ijmin=i;
                   4802:          }
                   4803:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   4804:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   4805:          if(j<0){
                   4806:            nberr++;
                   4807:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4808:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4809:          }
                   4810:          sum=sum+j;
                   4811:        }
                   4812:        jk= j/stepm;
                   4813:        jl= j -jk*stepm;
                   4814:        ju= j -(jk+1)*stepm;
                   4815:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   4816:          if(jl==0){
                   4817:            dh[mi][i]=jk;
                   4818:            bh[mi][i]=0;
                   4819:          }else{ /* We want a negative bias in order to only have interpolation ie
                   4820:                  * to avoid the price of an extra matrix product in likelihood */
                   4821:            dh[mi][i]=jk+1;
                   4822:            bh[mi][i]=ju;
                   4823:          }
                   4824:        }else{
                   4825:          if(jl <= -ju){
                   4826:            dh[mi][i]=jk;
                   4827:            bh[mi][i]=jl;       /* bias is positive if real duration
                   4828:                                 * is higher than the multiple of stepm and negative otherwise.
                   4829:                                 */
                   4830:          }
                   4831:          else{
                   4832:            dh[mi][i]=jk+1;
                   4833:            bh[mi][i]=ju;
                   4834:          }
                   4835:          if(dh[mi][i]==0){
                   4836:            dh[mi][i]=1; /* At least one step */
                   4837:            bh[mi][i]=ju; /* At least one step */
                   4838:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   4839:          }
                   4840:        } /* end if mle */
1.126     brouard  4841:       }
                   4842:     } /* end wave */
                   4843:   }
                   4844:   jmean=sum/k;
                   4845:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  4846:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  4847: }
1.126     brouard  4848: 
                   4849: /*********** Tricode ****************************/
1.220     brouard  4850:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  4851:  {
                   4852:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   4853:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   4854:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   4855:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   4856:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   4857:     */
1.130     brouard  4858: 
1.242     brouard  4859:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   4860:    int modmaxcovj=0; /* Modality max of covariates j */
                   4861:    int cptcode=0; /* Modality max of covariates j */
                   4862:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  4863: 
                   4864: 
1.242     brouard  4865:    /* cptcoveff=0;  */
                   4866:    /* *cptcov=0; */
1.126     brouard  4867:  
1.242     brouard  4868:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  4869: 
1.242     brouard  4870:    /* Loop on covariates without age and products and no quantitative variable */
                   4871:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   4872:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   4873:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   4874:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   4875:        switch(Fixed[k]) {
                   4876:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   4877:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   4878:           ij=(int)(covar[Tvar[k]][i]);
                   4879:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   4880:            * If product of Vn*Vm, still boolean *:
                   4881:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   4882:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   4883:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   4884:              modality of the nth covariate of individual i. */
                   4885:           if (ij > modmaxcovj)
                   4886:             modmaxcovj=ij; 
                   4887:           else if (ij < modmincovj) 
                   4888:             modmincovj=ij; 
                   4889:           if ((ij < -1) && (ij > NCOVMAX)){
                   4890:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   4891:             exit(1);
                   4892:           }else
                   4893:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   4894:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   4895:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   4896:           /* getting the maximum value of the modality of the covariate
                   4897:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   4898:              female ies 1, then modmaxcovj=1.
                   4899:           */
                   4900:         } /* end for loop on individuals i */
                   4901:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   4902:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   4903:         cptcode=modmaxcovj;
                   4904:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   4905:         /*for (i=0; i<=cptcode; i++) {*/
                   4906:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   4907:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   4908:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   4909:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   4910:             if( j != -1){
                   4911:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   4912:                                  covariate for which somebody answered excluding 
                   4913:                                  undefined. Usually 2: 0 and 1. */
                   4914:             }
                   4915:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   4916:                                     covariate for which somebody answered including 
                   4917:                                     undefined. Usually 3: -1, 0 and 1. */
                   4918:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   4919:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   4920:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  4921:                        
1.242     brouard  4922:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   4923:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   4924:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   4925:         /* modmincovj=3; modmaxcovj = 7; */
                   4926:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   4927:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   4928:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   4929:         /* nbcode[Tvar[j]][ij]=k; */
                   4930:         /* nbcode[Tvar[j]][1]=0; */
                   4931:         /* nbcode[Tvar[j]][2]=1; */
                   4932:         /* nbcode[Tvar[j]][3]=2; */
                   4933:         /* To be continued (not working yet). */
                   4934:         ij=0; /* ij is similar to i but can jump over null modalities */
                   4935:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   4936:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   4937:             break;
                   4938:           }
                   4939:           ij++;
                   4940:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   4941:           cptcode = ij; /* New max modality for covar j */
                   4942:         } /* end of loop on modality i=-1 to 1 or more */
                   4943:         break;
                   4944:        case 1: /* Testing on varying covariate, could be simple and
                   4945:                * should look at waves or product of fixed *
                   4946:                * varying. No time to test -1, assuming 0 and 1 only */
                   4947:         ij=0;
                   4948:         for(i=0; i<=1;i++){
                   4949:           nbcode[Tvar[k]][++ij]=i;
                   4950:         }
                   4951:         break;
                   4952:        default:
                   4953:         break;
                   4954:        } /* end switch */
                   4955:      } /* end dummy test */
                   4956:     
                   4957:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   4958:      /*        /\*recode from 0 *\/ */
                   4959:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   4960:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   4961:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   4962:      /*        } */
                   4963:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   4964:      /*        if (ij > ncodemax[j]) { */
                   4965:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   4966:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   4967:      /*          break; */
                   4968:      /*        } */
                   4969:      /*   }  /\* end of loop on modality k *\/ */
                   4970:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   4971:   
                   4972:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   4973:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   4974:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   4975:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   4976:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   4977:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   4978:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   4979:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   4980:   
                   4981:    ij=0;
                   4982:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   4983:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   4984:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   4985:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   4986:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   4987:        /* If product not in single variable we don't print results */
                   4988:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   4989:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   4990:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   4991:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   4992:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   4993:        if(Fixed[k]!=0)
                   4994:         anyvaryingduminmodel=1;
                   4995:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   4996:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   4997:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   4998:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   4999:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5000:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5001:      } 
                   5002:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5003:    /* ij--; */
                   5004:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5005:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5006:                * because they can be excluded from the model and real
                   5007:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5008:    for(j=ij+1; j<= cptcovt; j++){
                   5009:      Tvaraff[j]=0;
                   5010:      Tmodelind[j]=0;
                   5011:    }
                   5012:    for(j=ntveff+1; j<= cptcovt; j++){
                   5013:      TmodelInvind[j]=0;
                   5014:    }
                   5015:    /* To be sorted */
                   5016:    ;
                   5017:  }
1.126     brouard  5018: 
1.145     brouard  5019: 
1.126     brouard  5020: /*********** Health Expectancies ****************/
                   5021: 
1.235     brouard  5022:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5023: 
                   5024: {
                   5025:   /* Health expectancies, no variances */
1.164     brouard  5026:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5027:   int nhstepma, nstepma; /* Decreasing with age */
                   5028:   double age, agelim, hf;
                   5029:   double ***p3mat;
                   5030:   double eip;
                   5031: 
1.238     brouard  5032:   /* pstamp(ficreseij); */
1.126     brouard  5033:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5034:   fprintf(ficreseij,"# Age");
                   5035:   for(i=1; i<=nlstate;i++){
                   5036:     for(j=1; j<=nlstate;j++){
                   5037:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5038:     }
                   5039:     fprintf(ficreseij," e%1d. ",i);
                   5040:   }
                   5041:   fprintf(ficreseij,"\n");
                   5042: 
                   5043:   
                   5044:   if(estepm < stepm){
                   5045:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5046:   }
                   5047:   else  hstepm=estepm;   
                   5048:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5049:    * This is mainly to measure the difference between two models: for example
                   5050:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5051:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5052:    * progression in between and thus overestimating or underestimating according
                   5053:    * to the curvature of the survival function. If, for the same date, we 
                   5054:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5055:    * to compare the new estimate of Life expectancy with the same linear 
                   5056:    * hypothesis. A more precise result, taking into account a more precise
                   5057:    * curvature will be obtained if estepm is as small as stepm. */
                   5058: 
                   5059:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5060:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5061:      nhstepm is the number of hstepm from age to agelim 
                   5062:      nstepm is the number of stepm from age to agelin. 
                   5063:      Look at hpijx to understand the reason of that which relies in memory size
                   5064:      and note for a fixed period like estepm months */
                   5065:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5066:      survival function given by stepm (the optimization length). Unfortunately it
                   5067:      means that if the survival funtion is printed only each two years of age and if
                   5068:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5069:      results. So we changed our mind and took the option of the best precision.
                   5070:   */
                   5071:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5072: 
                   5073:   agelim=AGESUP;
                   5074:   /* If stepm=6 months */
                   5075:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5076:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5077:     
                   5078: /* nhstepm age range expressed in number of stepm */
                   5079:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5080:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5081:   /* if (stepm >= YEARM) hstepm=1;*/
                   5082:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5083:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5084: 
                   5085:   for (age=bage; age<=fage; age ++){ 
                   5086:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5087:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5088:     /* if (stepm >= YEARM) hstepm=1;*/
                   5089:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5090: 
                   5091:     /* If stepm=6 months */
                   5092:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5093:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5094:     
1.235     brouard  5095:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5096:     
                   5097:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5098:     
                   5099:     printf("%d|",(int)age);fflush(stdout);
                   5100:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5101:     
                   5102:     /* Computing expectancies */
                   5103:     for(i=1; i<=nlstate;i++)
                   5104:       for(j=1; j<=nlstate;j++)
                   5105:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5106:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5107:          
                   5108:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5109: 
                   5110:        }
                   5111: 
                   5112:     fprintf(ficreseij,"%3.0f",age );
                   5113:     for(i=1; i<=nlstate;i++){
                   5114:       eip=0;
                   5115:       for(j=1; j<=nlstate;j++){
                   5116:        eip +=eij[i][j][(int)age];
                   5117:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5118:       }
                   5119:       fprintf(ficreseij,"%9.4f", eip );
                   5120:     }
                   5121:     fprintf(ficreseij,"\n");
                   5122:     
                   5123:   }
                   5124:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5125:   printf("\n");
                   5126:   fprintf(ficlog,"\n");
                   5127:   
                   5128: }
                   5129: 
1.235     brouard  5130:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5131: 
                   5132: {
                   5133:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5134:      to initial status i, ei. .
1.126     brouard  5135:   */
                   5136:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5137:   int nhstepma, nstepma; /* Decreasing with age */
                   5138:   double age, agelim, hf;
                   5139:   double ***p3matp, ***p3matm, ***varhe;
                   5140:   double **dnewm,**doldm;
                   5141:   double *xp, *xm;
                   5142:   double **gp, **gm;
                   5143:   double ***gradg, ***trgradg;
                   5144:   int theta;
                   5145: 
                   5146:   double eip, vip;
                   5147: 
                   5148:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5149:   xp=vector(1,npar);
                   5150:   xm=vector(1,npar);
                   5151:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5152:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5153:   
                   5154:   pstamp(ficresstdeij);
                   5155:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5156:   fprintf(ficresstdeij,"# Age");
                   5157:   for(i=1; i<=nlstate;i++){
                   5158:     for(j=1; j<=nlstate;j++)
                   5159:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5160:     fprintf(ficresstdeij," e%1d. ",i);
                   5161:   }
                   5162:   fprintf(ficresstdeij,"\n");
                   5163: 
                   5164:   pstamp(ficrescveij);
                   5165:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5166:   fprintf(ficrescveij,"# Age");
                   5167:   for(i=1; i<=nlstate;i++)
                   5168:     for(j=1; j<=nlstate;j++){
                   5169:       cptj= (j-1)*nlstate+i;
                   5170:       for(i2=1; i2<=nlstate;i2++)
                   5171:        for(j2=1; j2<=nlstate;j2++){
                   5172:          cptj2= (j2-1)*nlstate+i2;
                   5173:          if(cptj2 <= cptj)
                   5174:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5175:        }
                   5176:     }
                   5177:   fprintf(ficrescveij,"\n");
                   5178:   
                   5179:   if(estepm < stepm){
                   5180:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5181:   }
                   5182:   else  hstepm=estepm;   
                   5183:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5184:    * This is mainly to measure the difference between two models: for example
                   5185:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5186:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5187:    * progression in between and thus overestimating or underestimating according
                   5188:    * to the curvature of the survival function. If, for the same date, we 
                   5189:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5190:    * to compare the new estimate of Life expectancy with the same linear 
                   5191:    * hypothesis. A more precise result, taking into account a more precise
                   5192:    * curvature will be obtained if estepm is as small as stepm. */
                   5193: 
                   5194:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5195:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5196:      nhstepm is the number of hstepm from age to agelim 
                   5197:      nstepm is the number of stepm from age to agelin. 
                   5198:      Look at hpijx to understand the reason of that which relies in memory size
                   5199:      and note for a fixed period like estepm months */
                   5200:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5201:      survival function given by stepm (the optimization length). Unfortunately it
                   5202:      means that if the survival funtion is printed only each two years of age and if
                   5203:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5204:      results. So we changed our mind and took the option of the best precision.
                   5205:   */
                   5206:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5207: 
                   5208:   /* If stepm=6 months */
                   5209:   /* nhstepm age range expressed in number of stepm */
                   5210:   agelim=AGESUP;
                   5211:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5212:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5213:   /* if (stepm >= YEARM) hstepm=1;*/
                   5214:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5215:   
                   5216:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5217:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5218:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5219:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5220:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5221:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5222: 
                   5223:   for (age=bage; age<=fage; age ++){ 
                   5224:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5225:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5226:     /* if (stepm >= YEARM) hstepm=1;*/
                   5227:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5228:                
1.126     brouard  5229:     /* If stepm=6 months */
                   5230:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5231:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5232:     
                   5233:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5234:                
1.126     brouard  5235:     /* Computing  Variances of health expectancies */
                   5236:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5237:        decrease memory allocation */
                   5238:     for(theta=1; theta <=npar; theta++){
                   5239:       for(i=1; i<=npar; i++){ 
1.222     brouard  5240:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5241:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5242:       }
1.235     brouard  5243:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5244:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5245:                        
1.126     brouard  5246:       for(j=1; j<= nlstate; j++){
1.222     brouard  5247:        for(i=1; i<=nlstate; i++){
                   5248:          for(h=0; h<=nhstepm-1; h++){
                   5249:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5250:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5251:          }
                   5252:        }
1.126     brouard  5253:       }
1.218     brouard  5254:                        
1.126     brouard  5255:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5256:        for(h=0; h<=nhstepm-1; h++){
                   5257:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5258:        }
1.126     brouard  5259:     }/* End theta */
                   5260:     
                   5261:     
                   5262:     for(h=0; h<=nhstepm-1; h++)
                   5263:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5264:        for(theta=1; theta <=npar; theta++)
                   5265:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5266:     
1.218     brouard  5267:                
1.222     brouard  5268:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5269:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5270:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5271:                
1.222     brouard  5272:     printf("%d|",(int)age);fflush(stdout);
                   5273:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5274:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5275:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5276:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5277:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5278:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5279:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5280:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5281:       }
                   5282:     }
1.218     brouard  5283:                
1.126     brouard  5284:     /* Computing expectancies */
1.235     brouard  5285:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5286:     for(i=1; i<=nlstate;i++)
                   5287:       for(j=1; j<=nlstate;j++)
1.222     brouard  5288:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5289:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5290:                                        
1.222     brouard  5291:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5292:                                        
1.222     brouard  5293:        }
1.218     brouard  5294:                
1.126     brouard  5295:     fprintf(ficresstdeij,"%3.0f",age );
                   5296:     for(i=1; i<=nlstate;i++){
                   5297:       eip=0.;
                   5298:       vip=0.;
                   5299:       for(j=1; j<=nlstate;j++){
1.222     brouard  5300:        eip += eij[i][j][(int)age];
                   5301:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5302:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5303:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5304:       }
                   5305:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5306:     }
                   5307:     fprintf(ficresstdeij,"\n");
1.218     brouard  5308:                
1.126     brouard  5309:     fprintf(ficrescveij,"%3.0f",age );
                   5310:     for(i=1; i<=nlstate;i++)
                   5311:       for(j=1; j<=nlstate;j++){
1.222     brouard  5312:        cptj= (j-1)*nlstate+i;
                   5313:        for(i2=1; i2<=nlstate;i2++)
                   5314:          for(j2=1; j2<=nlstate;j2++){
                   5315:            cptj2= (j2-1)*nlstate+i2;
                   5316:            if(cptj2 <= cptj)
                   5317:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5318:          }
1.126     brouard  5319:       }
                   5320:     fprintf(ficrescveij,"\n");
1.218     brouard  5321:                
1.126     brouard  5322:   }
                   5323:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5324:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5325:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5326:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5327:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5328:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5329:   printf("\n");
                   5330:   fprintf(ficlog,"\n");
1.218     brouard  5331:        
1.126     brouard  5332:   free_vector(xm,1,npar);
                   5333:   free_vector(xp,1,npar);
                   5334:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5335:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5336:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5337: }
1.218     brouard  5338:  
1.126     brouard  5339: /************ Variance ******************/
1.235     brouard  5340:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5341:  {
                   5342:    /* Variance of health expectancies */
                   5343:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5344:    /* double **newm;*/
                   5345:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5346:   
                   5347:    /* int movingaverage(); */
                   5348:    double **dnewm,**doldm;
                   5349:    double **dnewmp,**doldmp;
                   5350:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5351:    int k;
                   5352:    double *xp;
                   5353:    double **gp, **gm;  /* for var eij */
                   5354:    double ***gradg, ***trgradg; /*for var eij */
                   5355:    double **gradgp, **trgradgp; /* for var p point j */
                   5356:    double *gpp, *gmp; /* for var p point j */
                   5357:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5358:    double ***p3mat;
                   5359:    double age,agelim, hf;
                   5360:    /* double ***mobaverage; */
                   5361:    int theta;
                   5362:    char digit[4];
                   5363:    char digitp[25];
                   5364: 
                   5365:    char fileresprobmorprev[FILENAMELENGTH];
                   5366: 
                   5367:    if(popbased==1){
                   5368:      if(mobilav!=0)
                   5369:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5370:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5371:    }
                   5372:    else 
                   5373:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5374: 
1.218     brouard  5375:    /* if (mobilav!=0) { */
                   5376:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5377:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5378:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5379:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5380:    /*   } */
                   5381:    /* } */
                   5382: 
                   5383:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5384:    sprintf(digit,"%-d",ij);
                   5385:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5386:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5387:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5388:    strcat(fileresprobmorprev,fileresu);
                   5389:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5390:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5391:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5392:    }
                   5393:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5394:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5395:    pstamp(ficresprobmorprev);
                   5396:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5397:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5398:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5399:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5400:    }
                   5401:    for(j=1;j<=cptcoveff;j++) 
                   5402:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5403:    fprintf(ficresprobmorprev,"\n");
                   5404: 
1.218     brouard  5405:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5406:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5407:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5408:      for(i=1; i<=nlstate;i++)
                   5409:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5410:    }  
                   5411:    fprintf(ficresprobmorprev,"\n");
                   5412:   
                   5413:    fprintf(ficgp,"\n# Routine varevsij");
                   5414:    fprintf(ficgp,"\nunset title \n");
                   5415:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5416:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5417:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5418:    /*   } */
                   5419:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5420:    pstamp(ficresvij);
                   5421:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5422:    if(popbased==1)
                   5423:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5424:    else
                   5425:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5426:    fprintf(ficresvij,"# Age");
                   5427:    for(i=1; i<=nlstate;i++)
                   5428:      for(j=1; j<=nlstate;j++)
                   5429:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5430:    fprintf(ficresvij,"\n");
                   5431: 
                   5432:    xp=vector(1,npar);
                   5433:    dnewm=matrix(1,nlstate,1,npar);
                   5434:    doldm=matrix(1,nlstate,1,nlstate);
                   5435:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5436:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5437: 
                   5438:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5439:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5440:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5441:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5442:   
1.218     brouard  5443:    if(estepm < stepm){
                   5444:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5445:    }
                   5446:    else  hstepm=estepm;   
                   5447:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5448:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5449:       nhstepm is the number of hstepm from age to agelim 
                   5450:       nstepm is the number of stepm from age to agelim. 
                   5451:       Look at function hpijx to understand why because of memory size limitations, 
                   5452:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5453:       survival function given by stepm (the optimization length). Unfortunately it
                   5454:       means that if the survival funtion is printed every two years of age and if
                   5455:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5456:       results. So we changed our mind and took the option of the best precision.
                   5457:    */
                   5458:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5459:    agelim = AGESUP;
                   5460:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5461:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5462:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5463:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5464:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5465:      gp=matrix(0,nhstepm,1,nlstate);
                   5466:      gm=matrix(0,nhstepm,1,nlstate);
                   5467:                
                   5468:                
                   5469:      for(theta=1; theta <=npar; theta++){
                   5470:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5471:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5472:        }
                   5473:                        
1.242     brouard  5474:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5475:                        
                   5476:        if (popbased==1) {
                   5477:         if(mobilav ==0){
                   5478:           for(i=1; i<=nlstate;i++)
                   5479:             prlim[i][i]=probs[(int)age][i][ij];
                   5480:         }else{ /* mobilav */ 
                   5481:           for(i=1; i<=nlstate;i++)
                   5482:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5483:         }
                   5484:        }
                   5485:                        
1.235     brouard  5486:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5487:        for(j=1; j<= nlstate; j++){
                   5488:         for(h=0; h<=nhstepm; h++){
                   5489:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5490:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5491:         }
                   5492:        }
                   5493:        /* Next for computing probability of death (h=1 means
                   5494:          computed over hstepm matrices product = hstepm*stepm months) 
                   5495:          as a weighted average of prlim.
                   5496:        */
                   5497:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5498:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5499:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5500:        }    
                   5501:        /* end probability of death */
                   5502:                        
                   5503:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5504:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5505:                        
1.242     brouard  5506:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5507:                        
                   5508:        if (popbased==1) {
                   5509:         if(mobilav ==0){
                   5510:           for(i=1; i<=nlstate;i++)
                   5511:             prlim[i][i]=probs[(int)age][i][ij];
                   5512:         }else{ /* mobilav */ 
                   5513:           for(i=1; i<=nlstate;i++)
                   5514:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5515:         }
                   5516:        }
                   5517:                        
1.235     brouard  5518:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5519:                        
                   5520:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5521:         for(h=0; h<=nhstepm; h++){
                   5522:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5523:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5524:         }
                   5525:        }
                   5526:        /* This for computing probability of death (h=1 means
                   5527:          computed over hstepm matrices product = hstepm*stepm months) 
                   5528:          as a weighted average of prlim.
                   5529:        */
                   5530:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5531:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5532:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5533:        }    
                   5534:        /* end probability of death */
                   5535:                        
                   5536:        for(j=1; j<= nlstate; j++) /* vareij */
                   5537:         for(h=0; h<=nhstepm; h++){
                   5538:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5539:         }
                   5540:                        
                   5541:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5542:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5543:        }
                   5544:                        
                   5545:      } /* End theta */
                   5546:                
                   5547:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5548:                
                   5549:      for(h=0; h<=nhstepm; h++) /* veij */
                   5550:        for(j=1; j<=nlstate;j++)
                   5551:         for(theta=1; theta <=npar; theta++)
                   5552:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5553:                
                   5554:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5555:        for(theta=1; theta <=npar; theta++)
                   5556:         trgradgp[j][theta]=gradgp[theta][j];
                   5557:                
                   5558:                
                   5559:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5560:      for(i=1;i<=nlstate;i++)
                   5561:        for(j=1;j<=nlstate;j++)
                   5562:         vareij[i][j][(int)age] =0.;
                   5563:                
                   5564:      for(h=0;h<=nhstepm;h++){
                   5565:        for(k=0;k<=nhstepm;k++){
                   5566:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5567:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5568:         for(i=1;i<=nlstate;i++)
                   5569:           for(j=1;j<=nlstate;j++)
                   5570:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5571:        }
                   5572:      }
                   5573:                
                   5574:      /* pptj */
                   5575:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5576:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5577:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5578:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5579:         varppt[j][i]=doldmp[j][i];
                   5580:      /* end ppptj */
                   5581:      /*  x centered again */
                   5582:                
1.242     brouard  5583:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5584:                
                   5585:      if (popbased==1) {
                   5586:        if(mobilav ==0){
                   5587:         for(i=1; i<=nlstate;i++)
                   5588:           prlim[i][i]=probs[(int)age][i][ij];
                   5589:        }else{ /* mobilav */ 
                   5590:         for(i=1; i<=nlstate;i++)
                   5591:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   5592:        }
                   5593:      }
                   5594:                
                   5595:      /* This for computing probability of death (h=1 means
                   5596:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   5597:        as a weighted average of prlim.
                   5598:      */
1.235     brouard  5599:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  5600:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5601:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   5602:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   5603:      }    
                   5604:      /* end probability of death */
                   5605:                
                   5606:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   5607:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5608:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   5609:        for(i=1; i<=nlstate;i++){
                   5610:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   5611:        }
                   5612:      } 
                   5613:      fprintf(ficresprobmorprev,"\n");
                   5614:                
                   5615:      fprintf(ficresvij,"%.0f ",age );
                   5616:      for(i=1; i<=nlstate;i++)
                   5617:        for(j=1; j<=nlstate;j++){
                   5618:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   5619:        }
                   5620:      fprintf(ficresvij,"\n");
                   5621:      free_matrix(gp,0,nhstepm,1,nlstate);
                   5622:      free_matrix(gm,0,nhstepm,1,nlstate);
                   5623:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   5624:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   5625:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5626:    } /* End age */
                   5627:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   5628:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   5629:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   5630:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   5631:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   5632:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   5633:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   5634:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   5635:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5636:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   5637:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5638:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5639:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   5640:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   5641:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   5642:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   5643:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5644:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  5645:     */
1.218     brouard  5646:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   5647:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  5648: 
1.218     brouard  5649:    free_vector(xp,1,npar);
                   5650:    free_matrix(doldm,1,nlstate,1,nlstate);
                   5651:    free_matrix(dnewm,1,nlstate,1,npar);
                   5652:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5653:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   5654:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5655:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5656:    fclose(ficresprobmorprev);
                   5657:    fflush(ficgp);
                   5658:    fflush(fichtm); 
                   5659:  }  /* end varevsij */
1.126     brouard  5660: 
                   5661: /************ Variance of prevlim ******************/
1.235     brouard  5662:  void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  5663: {
1.205     brouard  5664:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  5665:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  5666: 
1.126     brouard  5667:   double **dnewm,**doldm;
                   5668:   int i, j, nhstepm, hstepm;
                   5669:   double *xp;
                   5670:   double *gp, *gm;
                   5671:   double **gradg, **trgradg;
1.208     brouard  5672:   double **mgm, **mgp;
1.126     brouard  5673:   double age,agelim;
                   5674:   int theta;
                   5675:   
                   5676:   pstamp(ficresvpl);
                   5677:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  5678:   fprintf(ficresvpl,"# Age ");
                   5679:   if(nresult >=1)
                   5680:     fprintf(ficresvpl," Result# ");
1.126     brouard  5681:   for(i=1; i<=nlstate;i++)
                   5682:       fprintf(ficresvpl," %1d-%1d",i,i);
                   5683:   fprintf(ficresvpl,"\n");
                   5684: 
                   5685:   xp=vector(1,npar);
                   5686:   dnewm=matrix(1,nlstate,1,npar);
                   5687:   doldm=matrix(1,nlstate,1,nlstate);
                   5688:   
                   5689:   hstepm=1*YEARM; /* Every year of age */
                   5690:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   5691:   agelim = AGESUP;
                   5692:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5693:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5694:     if (stepm >= YEARM) hstepm=1;
                   5695:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   5696:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  5697:     mgp=matrix(1,npar,1,nlstate);
                   5698:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  5699:     gp=vector(1,nlstate);
                   5700:     gm=vector(1,nlstate);
                   5701: 
                   5702:     for(theta=1; theta <=npar; theta++){
                   5703:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   5704:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5705:       }
1.209     brouard  5706:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5707:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5708:       else
1.235     brouard  5709:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5710:       for(i=1;i<=nlstate;i++){
1.126     brouard  5711:        gp[i] = prlim[i][i];
1.208     brouard  5712:        mgp[theta][i] = prlim[i][i];
                   5713:       }
1.126     brouard  5714:       for(i=1; i<=npar; i++) /* Computes gradient */
                   5715:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  5716:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5717:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5718:       else
1.235     brouard  5719:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5720:       for(i=1;i<=nlstate;i++){
1.126     brouard  5721:        gm[i] = prlim[i][i];
1.208     brouard  5722:        mgm[theta][i] = prlim[i][i];
                   5723:       }
1.126     brouard  5724:       for(i=1;i<=nlstate;i++)
                   5725:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  5726:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  5727:     } /* End theta */
                   5728: 
                   5729:     trgradg =matrix(1,nlstate,1,npar);
                   5730: 
                   5731:     for(j=1; j<=nlstate;j++)
                   5732:       for(theta=1; theta <=npar; theta++)
                   5733:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  5734:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5735:     /*   printf("\nmgm mgp %d ",(int)age); */
                   5736:     /*   for(j=1; j<=nlstate;j++){ */
                   5737:     /*         printf(" %d ",j); */
                   5738:     /*         for(theta=1; theta <=npar; theta++) */
                   5739:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   5740:     /*         printf("\n "); */
                   5741:     /*   } */
                   5742:     /* } */
                   5743:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5744:     /*   printf("\n gradg %d ",(int)age); */
                   5745:     /*   for(j=1; j<=nlstate;j++){ */
                   5746:     /*         printf("%d ",j); */
                   5747:     /*         for(theta=1; theta <=npar; theta++) */
                   5748:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   5749:     /*         printf("\n "); */
                   5750:     /*   } */
                   5751:     /* } */
1.126     brouard  5752: 
                   5753:     for(i=1;i<=nlstate;i++)
                   5754:       varpl[i][(int)age] =0.;
1.209     brouard  5755:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.205     brouard  5756:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   5757:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
                   5758:     }else{
1.126     brouard  5759:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   5760:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  5761:     }
1.126     brouard  5762:     for(i=1;i<=nlstate;i++)
                   5763:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   5764: 
                   5765:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  5766:     if(nresult >=1)
                   5767:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  5768:     for(i=1; i<=nlstate;i++)
                   5769:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   5770:     fprintf(ficresvpl,"\n");
                   5771:     free_vector(gp,1,nlstate);
                   5772:     free_vector(gm,1,nlstate);
1.208     brouard  5773:     free_matrix(mgm,1,npar,1,nlstate);
                   5774:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  5775:     free_matrix(gradg,1,npar,1,nlstate);
                   5776:     free_matrix(trgradg,1,nlstate,1,npar);
                   5777:   } /* End age */
                   5778: 
                   5779:   free_vector(xp,1,npar);
                   5780:   free_matrix(doldm,1,nlstate,1,npar);
                   5781:   free_matrix(dnewm,1,nlstate,1,nlstate);
                   5782: 
                   5783: }
                   5784: 
                   5785: /************ Variance of one-step probabilities  ******************/
                   5786: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  5787:  {
                   5788:    int i, j=0,  k1, l1, tj;
                   5789:    int k2, l2, j1,  z1;
                   5790:    int k=0, l;
                   5791:    int first=1, first1, first2;
                   5792:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   5793:    double **dnewm,**doldm;
                   5794:    double *xp;
                   5795:    double *gp, *gm;
                   5796:    double **gradg, **trgradg;
                   5797:    double **mu;
                   5798:    double age, cov[NCOVMAX+1];
                   5799:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   5800:    int theta;
                   5801:    char fileresprob[FILENAMELENGTH];
                   5802:    char fileresprobcov[FILENAMELENGTH];
                   5803:    char fileresprobcor[FILENAMELENGTH];
                   5804:    double ***varpij;
                   5805: 
                   5806:    strcpy(fileresprob,"PROB_"); 
                   5807:    strcat(fileresprob,fileres);
                   5808:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   5809:      printf("Problem with resultfile: %s\n", fileresprob);
                   5810:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   5811:    }
                   5812:    strcpy(fileresprobcov,"PROBCOV_"); 
                   5813:    strcat(fileresprobcov,fileresu);
                   5814:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   5815:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   5816:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   5817:    }
                   5818:    strcpy(fileresprobcor,"PROBCOR_"); 
                   5819:    strcat(fileresprobcor,fileresu);
                   5820:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   5821:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   5822:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   5823:    }
                   5824:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   5825:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   5826:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   5827:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   5828:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   5829:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   5830:    pstamp(ficresprob);
                   5831:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   5832:    fprintf(ficresprob,"# Age");
                   5833:    pstamp(ficresprobcov);
                   5834:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   5835:    fprintf(ficresprobcov,"# Age");
                   5836:    pstamp(ficresprobcor);
                   5837:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   5838:    fprintf(ficresprobcor,"# Age");
1.126     brouard  5839: 
                   5840: 
1.222     brouard  5841:    for(i=1; i<=nlstate;i++)
                   5842:      for(j=1; j<=(nlstate+ndeath);j++){
                   5843:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   5844:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   5845:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   5846:      }  
                   5847:    /* fprintf(ficresprob,"\n");
                   5848:       fprintf(ficresprobcov,"\n");
                   5849:       fprintf(ficresprobcor,"\n");
                   5850:    */
                   5851:    xp=vector(1,npar);
                   5852:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   5853:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   5854:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   5855:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   5856:    first=1;
                   5857:    fprintf(ficgp,"\n# Routine varprob");
                   5858:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   5859:    fprintf(fichtm,"\n");
                   5860: 
                   5861:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.</li>\n",optionfilehtmcov);
                   5862:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   5863:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  5864: and drawn. It helps understanding how is the covariance between two incidences.\
                   5865:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  5866:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  5867: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   5868: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   5869: standard deviations wide on each axis. <br>\
                   5870:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   5871:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   5872: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   5873: 
1.222     brouard  5874:    cov[1]=1;
                   5875:    /* tj=cptcoveff; */
1.225     brouard  5876:    tj = (int) pow(2,cptcoveff);
1.222     brouard  5877:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   5878:    j1=0;
1.224     brouard  5879:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  5880:      if  (cptcovn>0) {
                   5881:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  5882:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5883:        fprintf(ficresprob, "**********\n#\n");
                   5884:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  5885:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5886:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  5887:                        
1.222     brouard  5888:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  5889:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5890:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  5891:                        
                   5892:                        
1.222     brouard  5893:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  5894:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5895:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  5896:                        
1.222     brouard  5897:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  5898:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5899:        fprintf(ficresprobcor, "**********\n#");    
                   5900:        if(invalidvarcomb[j1]){
                   5901:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   5902:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   5903:         continue;
                   5904:        }
                   5905:      }
                   5906:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   5907:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   5908:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   5909:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   5910:      for (age=bage; age<=fage; age ++){ 
                   5911:        cov[2]=age;
                   5912:        if(nagesqr==1)
                   5913:         cov[3]= age*age;
                   5914:        for (k=1; k<=cptcovn;k++) {
                   5915:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   5916:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   5917:                                                                    * 1  1 1 1 1
                   5918:                                                                    * 2  2 1 1 1
                   5919:                                                                    * 3  1 2 1 1
                   5920:                                                                    */
                   5921:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   5922:        }
                   5923:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   5924:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   5925:        for (k=1; k<=cptcovprod;k++)
                   5926:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  5927:                        
                   5928:                        
1.222     brouard  5929:        for(theta=1; theta <=npar; theta++){
                   5930:         for(i=1; i<=npar; i++)
                   5931:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  5932:                                
1.222     brouard  5933:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  5934:                                
1.222     brouard  5935:         k=0;
                   5936:         for(i=1; i<= (nlstate); i++){
                   5937:           for(j=1; j<=(nlstate+ndeath);j++){
                   5938:             k=k+1;
                   5939:             gp[k]=pmmij[i][j];
                   5940:           }
                   5941:         }
1.220     brouard  5942:                                
1.222     brouard  5943:         for(i=1; i<=npar; i++)
                   5944:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  5945:                                
1.222     brouard  5946:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   5947:         k=0;
                   5948:         for(i=1; i<=(nlstate); i++){
                   5949:           for(j=1; j<=(nlstate+ndeath);j++){
                   5950:             k=k+1;
                   5951:             gm[k]=pmmij[i][j];
                   5952:           }
                   5953:         }
1.220     brouard  5954:                                
1.222     brouard  5955:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   5956:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   5957:        }
1.126     brouard  5958: 
1.222     brouard  5959:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   5960:         for(theta=1; theta <=npar; theta++)
                   5961:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  5962:                        
1.222     brouard  5963:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   5964:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  5965:                        
1.222     brouard  5966:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  5967:                        
1.222     brouard  5968:        k=0;
                   5969:        for(i=1; i<=(nlstate); i++){
                   5970:         for(j=1; j<=(nlstate+ndeath);j++){
                   5971:           k=k+1;
                   5972:           mu[k][(int) age]=pmmij[i][j];
                   5973:         }
                   5974:        }
                   5975:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   5976:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   5977:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  5978:                        
1.222     brouard  5979:        /*printf("\n%d ",(int)age);
                   5980:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   5981:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   5982:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   5983:         }*/
1.220     brouard  5984:                        
1.222     brouard  5985:        fprintf(ficresprob,"\n%d ",(int)age);
                   5986:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   5987:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  5988:                        
1.222     brouard  5989:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   5990:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   5991:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   5992:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   5993:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   5994:        }
                   5995:        i=0;
                   5996:        for (k=1; k<=(nlstate);k++){
                   5997:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   5998:           i++;
                   5999:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6000:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6001:           for (j=1; j<=i;j++){
                   6002:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6003:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6004:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6005:           }
                   6006:         }
                   6007:        }/* end of loop for state */
                   6008:      } /* end of loop for age */
                   6009:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6010:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6011:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6012:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6013:     
                   6014:      /* Confidence intervalle of pij  */
                   6015:      /*
                   6016:        fprintf(ficgp,"\nunset parametric;unset label");
                   6017:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6018:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6019:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6020:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6021:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6022:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6023:      */
                   6024:                
                   6025:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6026:      first1=1;first2=2;
                   6027:      for (k2=1; k2<=(nlstate);k2++){
                   6028:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6029:         if(l2==k2) continue;
                   6030:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6031:         for (k1=1; k1<=(nlstate);k1++){
                   6032:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6033:             if(l1==k1) continue;
                   6034:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6035:             if(i<=j) continue;
                   6036:             for (age=bage; age<=fage; age ++){ 
                   6037:               if ((int)age %5==0){
                   6038:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6039:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6040:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6041:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6042:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6043:                 c12=cv12/sqrt(v1*v2);
                   6044:                 /* Computing eigen value of matrix of covariance */
                   6045:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6046:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6047:                 if ((lc2 <0) || (lc1 <0) ){
                   6048:                   if(first2==1){
                   6049:                     first1=0;
                   6050:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6051:                   }
                   6052:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6053:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6054:                   /* lc2=fabs(lc2); */
                   6055:                 }
1.220     brouard  6056:                                                                
1.222     brouard  6057:                 /* Eigen vectors */
                   6058:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   6059:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6060:                 v21=(lc1-v1)/cv12*v11;
                   6061:                 v12=-v21;
                   6062:                 v22=v11;
                   6063:                 tnalp=v21/v11;
                   6064:                 if(first1==1){
                   6065:                   first1=0;
                   6066:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6067:                 }
                   6068:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6069:                 /*printf(fignu*/
                   6070:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6071:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6072:                 if(first==1){
                   6073:                   first=0;
                   6074:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6075:                   fprintf(ficgp,"\nset parametric;unset label");
                   6076:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6077:                   fprintf(ficgp,"\nset ter svg size 640, 480");
                   6078:                   fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6079:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6080: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6081:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6082:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6083:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6084:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6085:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6086:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6087:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6088:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
                   6089:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                                                         \
                   6090:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6091:                 }else{
                   6092:                   first=0;
                   6093:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6094:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6095:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6096:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
                   6097:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                 \
                   6098:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6099:                 }/* if first */
                   6100:               } /* age mod 5 */
                   6101:             } /* end loop age */
                   6102:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6103:             first=1;
                   6104:           } /*l12 */
                   6105:         } /* k12 */
                   6106:        } /*l1 */
                   6107:      }/* k1 */
                   6108:    }  /* loop on combination of covariates j1 */
                   6109:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6110:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6111:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6112:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6113:    free_vector(xp,1,npar);
                   6114:    fclose(ficresprob);
                   6115:    fclose(ficresprobcov);
                   6116:    fclose(ficresprobcor);
                   6117:    fflush(ficgp);
                   6118:    fflush(fichtmcov);
                   6119:  }
1.126     brouard  6120: 
                   6121: 
                   6122: /******************* Printing html file ***********/
1.201     brouard  6123: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6124:                  int lastpass, int stepm, int weightopt, char model[],\
                   6125:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.217     brouard  6126:                  int popforecast, int prevfcast, int backcast, int estepm , \
1.213     brouard  6127:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   6128:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.237     brouard  6129:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6130: 
                   6131:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6132:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6133: </ul>");
1.237     brouard  6134:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6135: </ul>", model);
1.214     brouard  6136:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6137:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6138:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6139:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6140:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6141:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6142:    fprintf(fichtm,"\
                   6143:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6144:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6145:    fprintf(fichtm,"\
1.217     brouard  6146:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6147:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6148:    fprintf(fichtm,"\
1.126     brouard  6149:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6150:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6151:    fprintf(fichtm,"\
1.217     brouard  6152:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6153:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6154:    fprintf(fichtm,"\
1.211     brouard  6155:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6156:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6157:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6158:    if(prevfcast==1){
                   6159:      fprintf(fichtm,"\
                   6160:  - Prevalence projections by age and states:                           \
1.201     brouard  6161:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6162:    }
1.126     brouard  6163: 
1.222     brouard  6164:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
1.126     brouard  6165: 
1.225     brouard  6166:    m=pow(2,cptcoveff);
1.222     brouard  6167:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6168: 
1.222     brouard  6169:    jj1=0;
1.237     brouard  6170: 
                   6171:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6172:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.237     brouard  6173:      if(TKresult[nres]!= k1)
                   6174:        continue;
1.220     brouard  6175: 
1.222     brouard  6176:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6177:      jj1++;
                   6178:      if (cptcovn > 0) {
                   6179:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6180:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6181:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6182:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6183:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6184:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6185:        }
1.237     brouard  6186:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6187:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6188:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6189:       }
                   6190:        
1.230     brouard  6191:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6192:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6193:        if(invalidvarcomb[k1]){
                   6194:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6195:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6196:         continue;
                   6197:        }
                   6198:      }
                   6199:      /* aij, bij */
1.241     brouard  6200:      fprintf(fichtm,"<br>- Logit model (yours is: 1+age+%s), for example: logit(pij)=log(pij/pii)= aij+ bij age + V1 age + etc. as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
                   6201: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6202:      /* Pij */
1.241     brouard  6203:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6204: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6205:      /* Quasi-incidences */
                   6206:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6207:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6208:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6209: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6210: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6211:      /* Survival functions (period) in state j */
                   6212:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6213:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6214: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6215:      }
                   6216:      /* State specific survival functions (period) */
                   6217:      for(cpt=1; cpt<=nlstate;cpt++){
                   6218:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6219:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.241     brouard  6220:  <a href=\"%s_%d-%d-%d.svg\">%s_%d%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6221:      }
                   6222:      /* Period (stable) prevalence in each health state */
                   6223:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6224:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6225: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6226:      }
                   6227:      if(backcast==1){
                   6228:        /* Period (stable) back prevalence in each health state */
                   6229:        for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6230:         fprintf(fichtm,"<br>\n- Convergence to period (stable) back prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6231: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6232:        }
1.217     brouard  6233:      }
1.222     brouard  6234:      if(prevfcast==1){
                   6235:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6236:        for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6237:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f) up to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6238: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6239:        }
                   6240:      }
1.220     brouard  6241:         
1.222     brouard  6242:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6243:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6244: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6245:      }
                   6246:      /* } /\* end i1 *\/ */
                   6247:    }/* End k1 */
                   6248:    fprintf(fichtm,"</ul>");
1.126     brouard  6249: 
1.222     brouard  6250:    fprintf(fichtm,"\
1.126     brouard  6251: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6252:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6253:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6254: But because parameters are usually highly correlated (a higher incidence of disability \
                   6255: and a higher incidence of recovery can give very close observed transition) it might \
                   6256: be very useful to look not only at linear confidence intervals estimated from the \
                   6257: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6258: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6259: covariance matrix of the one-step probabilities. \
                   6260: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6261: 
1.222     brouard  6262:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6263:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6264:    fprintf(fichtm,"\
1.126     brouard  6265:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6266:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6267: 
1.222     brouard  6268:    fprintf(fichtm,"\
1.126     brouard  6269:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6270:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6271:    fprintf(fichtm,"\
1.126     brouard  6272:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6273:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6274:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6275:    fprintf(fichtm,"\
1.126     brouard  6276:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6277:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6278:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6279:    fprintf(fichtm,"\
1.128     brouard  6280:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6281:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6282:    fprintf(fichtm,"\
1.128     brouard  6283:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6284:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6285:    fprintf(fichtm,"\
1.126     brouard  6286:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6287:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6288: 
                   6289: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6290: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6291: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6292: /*     <br>",fileres,fileres,fileres,fileres); */
                   6293: /*  else  */
                   6294: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6295:    fflush(fichtm);
                   6296:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6297: 
1.225     brouard  6298:    m=pow(2,cptcoveff);
1.222     brouard  6299:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6300: 
1.222     brouard  6301:    jj1=0;
1.237     brouard  6302: 
1.241     brouard  6303:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6304:    for(k1=1; k1<=m;k1++){
1.237     brouard  6305:      if(TKresult[nres]!= k1)
                   6306:        continue;
1.222     brouard  6307:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6308:      jj1++;
1.126     brouard  6309:      if (cptcovn > 0) {
                   6310:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6311:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6312:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6313:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6314:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6315:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6316:       }
                   6317: 
1.126     brouard  6318:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6319: 
1.222     brouard  6320:        if(invalidvarcomb[k1]){
                   6321:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6322:         continue;
                   6323:        }
1.126     brouard  6324:      }
                   6325:      for(cpt=1; cpt<=nlstate;cpt++) {
1.218     brouard  6326:        fprintf(fichtm,"\n<br>- Observed (cross-sectional) and period (incidence based) \
1.241     brouard  6327: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
                   6328: <img src=\"%s_%d-%d-%d.svg\">",cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  6329:      }
                   6330:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6331: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6332: true period expectancies (those weighted with period prevalences are also\
                   6333:  drawn in addition to the population based expectancies computed using\
1.241     brouard  6334:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   6335: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  6336:      /* } /\* end i1 *\/ */
                   6337:    }/* End k1 */
1.241     brouard  6338:   }/* End nres */
1.222     brouard  6339:    fprintf(fichtm,"</ul>");
                   6340:    fflush(fichtm);
1.126     brouard  6341: }
                   6342: 
                   6343: /******************* Gnuplot file **************/
1.223     brouard  6344: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[]){
1.126     brouard  6345: 
                   6346:   char dirfileres[132],optfileres[132];
1.223     brouard  6347:   char gplotcondition[132];
1.237     brouard  6348:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6349:   int lv=0, vlv=0, kl=0;
1.130     brouard  6350:   int ng=0;
1.201     brouard  6351:   int vpopbased;
1.223     brouard  6352:   int ioffset; /* variable offset for columns */
1.235     brouard  6353:   int nres=0; /* Index of resultline */
1.219     brouard  6354: 
1.126     brouard  6355: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6356: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6357: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6358: /*   } */
                   6359: 
                   6360:   /*#ifdef windows */
                   6361:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6362:   /*#endif */
1.225     brouard  6363:   m=pow(2,cptcoveff);
1.126     brouard  6364: 
1.202     brouard  6365:   /* Contribution to likelihood */
                   6366:   /* Plot the probability implied in the likelihood */
1.223     brouard  6367:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6368:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6369:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6370:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6371: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6372:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6373: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6374:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6375:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6376:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6377:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6378:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6379:   for (i=1; i<= nlstate ; i ++) {
                   6380:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6381:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6382:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6383:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6384:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6385:     }
                   6386:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6387:   }
                   6388:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6389:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6390:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6391:   fprintf(ficgp,"\nset out;unset log\n");
                   6392:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6393: 
1.126     brouard  6394:   strcpy(dirfileres,optionfilefiname);
                   6395:   strcpy(optfileres,"vpl");
1.223     brouard  6396:   /* 1eme*/
1.238     brouard  6397:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   6398:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  6399:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  6400:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
                   6401:        if(TKresult[nres]!= k1)
                   6402:          continue;
                   6403:        /* We are interested in selected combination by the resultline */
1.246   ! brouard  6404:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  6405:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
                   6406:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6407:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   6408:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6409:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6410:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6411:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   6412:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246   ! brouard  6413:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  6414:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6415:        }
                   6416:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246   ! brouard  6417:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  6418:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6419:        }       
1.246   ! brouard  6420:        /* printf("\n#\n"); */
1.238     brouard  6421:        fprintf(ficgp,"\n#\n");
                   6422:        if(invalidvarcomb[k1]){
                   6423:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6424:          continue;
                   6425:        }
1.235     brouard  6426:       
1.241     brouard  6427:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   6428:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
                   6429:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres);
1.235     brouard  6430:       
1.238     brouard  6431:        for (i=1; i<= nlstate ; i ++) {
                   6432:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6433:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   6434:        }
1.242     brouard  6435:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres);
1.238     brouard  6436:        for (i=1; i<= nlstate ; i ++) {
                   6437:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6438:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6439:        } 
1.242     brouard  6440:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); 
1.238     brouard  6441:        for (i=1; i<= nlstate ; i ++) {
                   6442:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6443:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6444:        }  
                   6445:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1));
                   6446:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   6447:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  6448:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  6449:          if(cptcoveff ==0){
1.245     brouard  6450:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  6451:          }else{
                   6452:            kl=0;
                   6453:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   6454:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6455:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6456:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6457:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6458:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  6459:              kl++;
1.238     brouard  6460:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6461:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6462:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6463:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6464:              if(k==cptcoveff){
1.245     brouard  6465:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  6466:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  6467:              }else{
                   6468:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   6469:                kl++;
                   6470:              }
                   6471:            } /* end covariate */
                   6472:          } /* end if no covariate */
                   6473:        } /* end if backcast */
                   6474:        fprintf(ficgp,"\nset out \n");
                   6475:       } /* nres */
1.201     brouard  6476:     } /* k1 */
                   6477:   } /* cpt */
1.235     brouard  6478: 
                   6479:   
1.126     brouard  6480:   /*2 eme*/
1.238     brouard  6481:   for (k1=1; k1<= m ; k1 ++){  
                   6482:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6483:       if(TKresult[nres]!= k1)
                   6484:        continue;
                   6485:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
                   6486:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  6487:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6488:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6489:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6490:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6491:        vlv= nbcode[Tvaraff[k]][lv];
                   6492:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6493:       }
1.237     brouard  6494:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  6495:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  6496:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  6497:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  6498:       }
1.211     brouard  6499:       fprintf(ficgp,"\n#\n");
1.223     brouard  6500:       if(invalidvarcomb[k1]){
                   6501:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6502:        continue;
                   6503:       }
1.219     brouard  6504:                        
1.241     brouard  6505:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  6506:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
                   6507:        if(vpopbased==0)
                   6508:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
                   6509:        else
                   6510:          fprintf(ficgp,"\nreplot ");
                   6511:        for (i=1; i<= nlstate+1 ; i ++) {
                   6512:          k=2*i;
                   6513:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1, vpopbased);
                   6514:          for (j=1; j<= nlstate+1 ; j ++) {
                   6515:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6516:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6517:          }   
                   6518:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   6519:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
                   6520:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6521:          for (j=1; j<= nlstate+1 ; j ++) {
                   6522:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6523:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6524:          }   
                   6525:          fprintf(ficgp,"\" t\"\" w l lt 0,");
                   6526:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6527:          for (j=1; j<= nlstate+1 ; j ++) {
                   6528:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6529:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6530:          }   
                   6531:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   6532:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   6533:        } /* state */
                   6534:       } /* vpopbased */
1.244     brouard  6535:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  6536:     } /* end nres */
                   6537:   } /* k1 end 2 eme*/
                   6538:        
                   6539:        
                   6540:   /*3eme*/
                   6541:   for (k1=1; k1<= m ; k1 ++){
                   6542:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.240     brouard  6543:       if(TKresult[nres]!= k1)
1.238     brouard  6544:        continue;
                   6545: 
                   6546:       for (cpt=1; cpt<= nlstate ; cpt ++) {
                   6547:        fprintf(ficgp,"\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
                   6548:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6549:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6550:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6551:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6552:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6553:          vlv= nbcode[Tvaraff[k]][lv];
                   6554:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6555:        }
                   6556:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6557:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6558:        }       
                   6559:        fprintf(ficgp,"\n#\n");
                   6560:        if(invalidvarcomb[k1]){
                   6561:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6562:          continue;
                   6563:        }
                   6564:                        
                   6565:        /*       k=2+nlstate*(2*cpt-2); */
                   6566:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  6567:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.238     brouard  6568:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.201     brouard  6569: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),k1-1,k1-1,k,cpt);
1.238     brouard  6570:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6571:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6572:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   6573:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6574:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6575:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  6576:                                
1.238     brouard  6577:        */
                   6578:        for (i=1; i< nlstate ; i ++) {
                   6579:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+i,cpt,i+1);
                   6580:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  6581:                                
1.238     brouard  6582:        } 
                   6583:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+nlstate,cpt);
                   6584:       }
                   6585:     } /* end nres */
                   6586:   } /* end kl 3eme */
1.126     brouard  6587:   
1.223     brouard  6588:   /* 4eme */
1.201     brouard  6589:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  6590:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   6591:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6592:       if(TKresult[nres]!= k1)
1.223     brouard  6593:        continue;
1.238     brouard  6594:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
                   6595:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   6596:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6597:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6598:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6599:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6600:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6601:          vlv= nbcode[Tvaraff[k]][lv];
                   6602:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6603:        }
                   6604:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6605:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6606:        }       
                   6607:        fprintf(ficgp,"\n#\n");
                   6608:        if(invalidvarcomb[k1]){
                   6609:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6610:          continue;
1.223     brouard  6611:        }
1.238     brouard  6612:       
1.241     brouard  6613:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.238     brouard  6614:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6615: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6616:        k=3;
                   6617:        for (i=1; i<= nlstate ; i ++){
                   6618:          if(i==1){
                   6619:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6620:          }else{
                   6621:            fprintf(ficgp,", '' ");
                   6622:          }
                   6623:          l=(nlstate+ndeath)*(i-1)+1;
                   6624:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6625:          for (j=2; j<= nlstate+ndeath ; j ++)
                   6626:            fprintf(ficgp,"+$%d",k+l+j-1);
                   6627:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   6628:        } /* nlstate */
                   6629:        fprintf(ficgp,"\nset out\n");
                   6630:       } /* end cpt state*/ 
                   6631:     } /* end nres */
                   6632:   } /* end covariate k1 */  
                   6633: 
1.220     brouard  6634: /* 5eme */
1.201     brouard  6635:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  6636:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   6637:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6638:       if(TKresult[nres]!= k1)
1.227     brouard  6639:        continue;
1.238     brouard  6640:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
                   6641:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   6642:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6643:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6644:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6645:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6646:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6647:          vlv= nbcode[Tvaraff[k]][lv];
                   6648:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6649:        }
                   6650:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6651:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6652:        }       
                   6653:        fprintf(ficgp,"\n#\n");
                   6654:        if(invalidvarcomb[k1]){
                   6655:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6656:          continue;
                   6657:        }
1.227     brouard  6658:       
1.241     brouard  6659:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.238     brouard  6660:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6661: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6662:        k=3;
                   6663:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6664:          if(j==1)
                   6665:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6666:          else
                   6667:            fprintf(ficgp,", '' ");
                   6668:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6669:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   6670:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   6671:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   6672:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   6673:        } /* nlstate */
                   6674:        fprintf(ficgp,", '' ");
                   6675:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   6676:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6677:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6678:          if(j < nlstate)
                   6679:            fprintf(ficgp,"$%d +",k+l);
                   6680:          else
                   6681:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   6682:        }
                   6683:        fprintf(ficgp,"\nset out\n");
                   6684:       } /* end cpt state*/ 
                   6685:     } /* end covariate */  
                   6686:   } /* end nres */
1.227     brouard  6687:   
1.220     brouard  6688: /* 6eme */
1.202     brouard  6689:   /* CV preval stable (period) for each covariate */
1.237     brouard  6690:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6691:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6692:     if(TKresult[nres]!= k1)
                   6693:       continue;
1.153     brouard  6694:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6695:       
1.211     brouard  6696:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  6697:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  6698:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6699:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6700:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6701:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6702:        vlv= nbcode[Tvaraff[k]][lv];
                   6703:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6704:       }
1.237     brouard  6705:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6706:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6707:       }        
1.211     brouard  6708:       fprintf(ficgp,"\n#\n");
1.223     brouard  6709:       if(invalidvarcomb[k1]){
1.227     brouard  6710:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6711:        continue;
1.223     brouard  6712:       }
1.227     brouard  6713:       
1.241     brouard  6714:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.126     brouard  6715:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  6716: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6717:       k=3; /* Offset */
1.153     brouard  6718:       for (i=1; i<= nlstate ; i ++){
1.227     brouard  6719:        if(i==1)
                   6720:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6721:        else
                   6722:          fprintf(ficgp,", '' ");
                   6723:        l=(nlstate+ndeath)*(i-1)+1;
                   6724:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6725:        for (j=2; j<= nlstate ; j ++)
                   6726:          fprintf(ficgp,"+$%d",k+l+j-1);
                   6727:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  6728:       } /* nlstate */
1.201     brouard  6729:       fprintf(ficgp,"\nset out\n");
1.153     brouard  6730:     } /* end cpt state*/ 
                   6731:   } /* end covariate */  
1.227     brouard  6732:   
                   6733:   
1.220     brouard  6734: /* 7eme */
1.218     brouard  6735:   if(backcast == 1){
1.217     brouard  6736:     /* CV back preval stable (period) for each covariate */
1.237     brouard  6737:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6738:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6739:       if(TKresult[nres]!= k1)
                   6740:        continue;
1.218     brouard  6741:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6742:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
                   6743:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6744:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6745:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6746:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  6747:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  6748:          vlv= nbcode[Tvaraff[k]][lv];
                   6749:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6750:        }
1.237     brouard  6751:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6752:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6753:        }       
1.227     brouard  6754:        fprintf(ficgp,"\n#\n");
                   6755:        if(invalidvarcomb[k1]){
                   6756:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6757:          continue;
                   6758:        }
                   6759:        
1.241     brouard  6760:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.227     brouard  6761:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  6762: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  6763:        k=3; /* Offset */
                   6764:        for (i=1; i<= nlstate ; i ++){
                   6765:          if(i==1)
                   6766:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   6767:          else
                   6768:            fprintf(ficgp,", '' ");
                   6769:          /* l=(nlstate+ndeath)*(i-1)+1; */
                   6770:          l=(nlstate+ndeath)*(cpt-1)+1;
                   6771:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   6772:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
                   6773:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+(cpt-1)+i-1); /* a vérifier */
                   6774:          /* for (j=2; j<= nlstate ; j ++) */
                   6775:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   6776:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
                   6777:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",i,cpt);
                   6778:        } /* nlstate */
                   6779:        fprintf(ficgp,"\nset out\n");
1.218     brouard  6780:       } /* end cpt state*/ 
                   6781:     } /* end covariate */  
                   6782:   } /* End if backcast */
                   6783:   
1.223     brouard  6784:   /* 8eme */
1.218     brouard  6785:   if(prevfcast==1){
                   6786:     /* Projection from cross-sectional to stable (period) for each covariate */
                   6787:     
1.237     brouard  6788:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6789:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6790:       if(TKresult[nres]!= k1)
                   6791:        continue;
1.211     brouard  6792:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6793:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   6794:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   6795:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6796:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6797:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6798:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6799:          vlv= nbcode[Tvaraff[k]][lv];
                   6800:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6801:        }
1.237     brouard  6802:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6803:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6804:        }       
1.227     brouard  6805:        fprintf(ficgp,"\n#\n");
                   6806:        if(invalidvarcomb[k1]){
                   6807:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6808:          continue;
                   6809:        }
                   6810:        
                   6811:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  6812:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.227     brouard  6813:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  6814: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  6815:        for (i=1; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   6816:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6817:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   6818:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6819:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   6820:          if(i==1){
                   6821:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   6822:          }else{
                   6823:            fprintf(ficgp,",\\\n '' ");
                   6824:          }
                   6825:          if(cptcoveff ==0){ /* No covariate */
                   6826:            ioffset=2; /* Age is in 2 */
                   6827:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   6828:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   6829:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   6830:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   6831:            fprintf(ficgp," u %d:(", ioffset); 
                   6832:            if(i==nlstate+1)
                   6833:              fprintf(ficgp," $%d/(1.-$%d)) t 'pw.%d' with line ",      \
                   6834:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   6835:            else
                   6836:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   6837:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   6838:          }else{ /* more than 2 covariates */
                   6839:            if(cptcoveff ==1){
                   6840:              ioffset=4; /* Age is in 4 */
                   6841:            }else{
                   6842:              ioffset=6; /* Age is in 6 */
                   6843:              /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6844:              /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   6845:            }   
                   6846:            fprintf(ficgp," u %d:(",ioffset); 
                   6847:            kl=0;
                   6848:            strcpy(gplotcondition,"(");
                   6849:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   6850:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   6851:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6852:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6853:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6854:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   6855:              kl++;
                   6856:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   6857:              kl++;
                   6858:              if(k <cptcoveff && cptcoveff>1)
                   6859:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   6860:            }
                   6861:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   6862:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6863:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6864:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6865:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6866:            if(i==nlstate+1){
                   6867:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p.%d' with line ", gplotcondition, \
                   6868:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   6869:            }else{
                   6870:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   6871:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   6872:            }
                   6873:          } /* end if covariate */
                   6874:        } /* nlstate */
                   6875:        fprintf(ficgp,"\nset out\n");
1.223     brouard  6876:       } /* end cpt state*/
                   6877:     } /* end covariate */
                   6878:   } /* End if prevfcast */
1.227     brouard  6879:   
                   6880:   
1.238     brouard  6881:   /* 9eme writing MLE parameters */
                   6882:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  6883:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  6884:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  6885:     for(k=1; k <=(nlstate+ndeath); k++){
                   6886:       if (k != i) {
1.227     brouard  6887:        fprintf(ficgp,"#   current state %d\n",k);
                   6888:        for(j=1; j <=ncovmodel; j++){
                   6889:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   6890:          jk++; 
                   6891:        }
                   6892:        fprintf(ficgp,"\n");
1.126     brouard  6893:       }
                   6894:     }
1.223     brouard  6895:   }
1.187     brouard  6896:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  6897:   
1.145     brouard  6898:   /*goto avoid;*/
1.238     brouard  6899:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   6900:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  6901:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   6902:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   6903:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   6904:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   6905:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   6906:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   6907:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   6908:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   6909:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   6910:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   6911:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   6912:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   6913:   fprintf(ficgp,"#\n");
1.223     brouard  6914:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  6915:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  6916:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  6917:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.237     brouard  6918:     fprintf(ficgp,"#   jk=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   6919:     for(jk=1; jk <=m; jk++)  /* For each combination of covariate */
                   6920:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6921:       if(TKresult[nres]!= jk)
                   6922:        continue;
                   6923:       fprintf(ficgp,"# Combination of dummy  jk=%d and ",jk);
                   6924:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6925:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6926:       }        
                   6927:       fprintf(ficgp,"\n#\n");
1.241     brouard  6928:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng,nres);
1.223     brouard  6929:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   6930:       if (ng==1){
                   6931:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   6932:        fprintf(ficgp,"\nunset log y");
                   6933:       }else if (ng==2){
                   6934:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   6935:        fprintf(ficgp,"\nset log y");
                   6936:       }else if (ng==3){
                   6937:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   6938:        fprintf(ficgp,"\nset log y");
                   6939:       }else
                   6940:        fprintf(ficgp,"\nunset title ");
                   6941:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   6942:       i=1;
                   6943:       for(k2=1; k2<=nlstate; k2++) {
                   6944:        k3=i;
                   6945:        for(k=1; k<=(nlstate+ndeath); k++) {
                   6946:          if (k != k2){
                   6947:            switch( ng) {
                   6948:            case 1:
                   6949:              if(nagesqr==0)
                   6950:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   6951:              else /* nagesqr =1 */
                   6952:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   6953:              break;
                   6954:            case 2: /* ng=2 */
                   6955:              if(nagesqr==0)
                   6956:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   6957:              else /* nagesqr =1 */
                   6958:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   6959:              break;
                   6960:            case 3:
                   6961:              if(nagesqr==0)
                   6962:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   6963:              else /* nagesqr =1 */
                   6964:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   6965:              break;
                   6966:            }
                   6967:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  6968:            ijp=1; /* product no age */
                   6969:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   6970:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  6971:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.237     brouard  6972:              if(j==Tage[ij]) { /* Product by age */
                   6973:                if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
1.238     brouard  6974:                  if(DummyV[j]==0){
1.237     brouard  6975:                    fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   6976:                  }else{ /* quantitative */
                   6977:                    fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   6978:                    /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   6979:                  }
                   6980:                  ij++;
                   6981:                }
                   6982:              }else if(j==Tprod[ijp]) { /* */ 
                   6983:                /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   6984:                if(ijp <=cptcovprod) { /* Product */
1.238     brouard  6985:                  if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   6986:                    if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
1.237     brouard  6987:                      /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],nbcode[Tvard[ijp][2]][codtabm(jk,j)]); */
                   6988:                      fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   6989:                    }else{ /* Vn is dummy and Vm is quanti */
                   6990:                      /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   6991:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   6992:                    }
                   6993:                  }else{ /* Vn*Vm Vn is quanti */
1.238     brouard  6994:                    if(DummyV[Tvard[ijp][2]]==0){
1.237     brouard  6995:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   6996:                    }else{ /* Both quanti */
                   6997:                      fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   6998:                    }
                   6999:                  }
1.238     brouard  7000:                  ijp++;
1.237     brouard  7001:                }
                   7002:              } else{  /* simple covariate */
                   7003:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(jk,j)]); /\* Valgrind bug nbcode *\/ */
                   7004:                if(Dummy[j]==0){
                   7005:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7006:                }else{ /* quantitative */
                   7007:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.223     brouard  7008:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7009:                }
1.237     brouard  7010:              } /* end simple */
                   7011:            } /* end j */
1.223     brouard  7012:          }else{
                   7013:            i=i-ncovmodel;
                   7014:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7015:              fprintf(ficgp," (1.");
                   7016:          }
1.227     brouard  7017:          
1.223     brouard  7018:          if(ng != 1){
                   7019:            fprintf(ficgp,")/(1");
1.227     brouard  7020:            
1.223     brouard  7021:            for(k1=1; k1 <=nlstate; k1++){ 
                   7022:              if(nagesqr==0)
                   7023:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                   7024:              else /* nagesqr =1 */
                   7025:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1,k3+(k1-1)*ncovmodel+1+nagesqr);
1.217     brouard  7026:               
1.223     brouard  7027:              ij=1;
                   7028:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.237     brouard  7029:                if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7030:                  if(ij <=cptcovage) { /* Bug valgrind */
1.223     brouard  7031:                    fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                   7032:                    /* fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7033:                    ij++;
                   7034:                  }
                   7035:                }
                   7036:                else
1.225     brouard  7037:                  fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7038:              }
                   7039:              fprintf(ficgp,")");
                   7040:            }
                   7041:            fprintf(ficgp,")");
                   7042:            if(ng ==2)
                   7043:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   7044:            else /* ng= 3 */
                   7045:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   7046:          }else{ /* end ng <> 1 */
                   7047:            if( k !=k2) /* logit p11 is hard to draw */
                   7048:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   7049:          }
                   7050:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7051:            fprintf(ficgp,",");
                   7052:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7053:            fprintf(ficgp,",");
                   7054:          i=i+ncovmodel;
                   7055:        } /* end k */
                   7056:       } /* end k2 */
                   7057:       fprintf(ficgp,"\n set out\n");
                   7058:     } /* end jk */
                   7059:   } /* end ng */
                   7060:   /* avoid: */
                   7061:   fflush(ficgp); 
1.126     brouard  7062: }  /* end gnuplot */
                   7063: 
                   7064: 
                   7065: /*************** Moving average **************/
1.219     brouard  7066: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  7067:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  7068:    
1.222     brouard  7069:    int i, cpt, cptcod;
                   7070:    int modcovmax =1;
                   7071:    int mobilavrange, mob;
                   7072:    int iage=0;
                   7073: 
                   7074:    double sum=0.;
                   7075:    double age;
                   7076:    double *sumnewp, *sumnewm;
                   7077:    double *agemingood, *agemaxgood; /* Currently identical for all covariates */
                   7078:   
                   7079:   
1.225     brouard  7080:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  7081:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   7082: 
                   7083:    sumnewp = vector(1,ncovcombmax);
                   7084:    sumnewm = vector(1,ncovcombmax);
                   7085:    agemingood = vector(1,ncovcombmax); 
                   7086:    agemaxgood = vector(1,ncovcombmax);
                   7087: 
                   7088:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7089:      sumnewm[cptcod]=0.;
                   7090:      sumnewp[cptcod]=0.;
                   7091:      agemingood[cptcod]=0;
                   7092:      agemaxgood[cptcod]=0;
                   7093:    }
                   7094:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   7095:   
                   7096:    if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   7097:      if(mobilav==1) mobilavrange=5; /* default */
                   7098:      else mobilavrange=mobilav;
                   7099:      for (age=bage; age<=fage; age++)
                   7100:        for (i=1; i<=nlstate;i++)
                   7101:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   7102:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   7103:      /* We keep the original values on the extreme ages bage, fage and for 
                   7104:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   7105:        we use a 5 terms etc. until the borders are no more concerned. 
                   7106:      */ 
                   7107:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   7108:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
                   7109:         for (i=1; i<=nlstate;i++){
                   7110:           for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7111:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   7112:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   7113:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   7114:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   7115:             }
                   7116:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
                   7117:           }
                   7118:         }
                   7119:        }/* end age */
                   7120:      }/* end mob */
                   7121:    }else
                   7122:      return -1;
                   7123:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7124:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7125:      if(invalidvarcomb[cptcod]){
                   7126:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7127:        continue;
                   7128:      }
1.219     brouard  7129: 
1.222     brouard  7130:      agemingood[cptcod]=fage-(mob-1)/2;
                   7131:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, finding the youngest wrong */
                   7132:        sumnewm[cptcod]=0.;
                   7133:        for (i=1; i<=nlstate;i++){
                   7134:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7135:        }
                   7136:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7137:         agemingood[cptcod]=age;
                   7138:        }else{ /* bad */
                   7139:         for (i=1; i<=nlstate;i++){
                   7140:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7141:         } /* i */
                   7142:        } /* end bad */
                   7143:      }/* age */
                   7144:      sum=0.;
                   7145:      for (i=1; i<=nlstate;i++){
                   7146:        sum+=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7147:      }
                   7148:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7149:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any descending age!\n",cptcod);
                   7150:        /* for (i=1; i<=nlstate;i++){ */
                   7151:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7152:        /* } /\* i *\/ */
                   7153:      } /* end bad */
                   7154:      /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   7155:      /* From youngest, finding the oldest wrong */
                   7156:      agemaxgood[cptcod]=bage+(mob-1)/2;
                   7157:      for (age=bage+(mob-1)/2; age<=fage; age++){
                   7158:        sumnewm[cptcod]=0.;
                   7159:        for (i=1; i<=nlstate;i++){
                   7160:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7161:        }
                   7162:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7163:         agemaxgood[cptcod]=age;
                   7164:        }else{ /* bad */
                   7165:         for (i=1; i<=nlstate;i++){
                   7166:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7167:         } /* i */
                   7168:        } /* end bad */
                   7169:      }/* age */
                   7170:      sum=0.;
                   7171:      for (i=1; i<=nlstate;i++){
                   7172:        sum+=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7173:      }
                   7174:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7175:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any ascending age!\n",cptcod);
                   7176:        /* for (i=1; i<=nlstate;i++){ */
                   7177:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7178:        /* } /\* i *\/ */
                   7179:      } /* end bad */
                   7180:                
                   7181:      for (age=bage; age<=fage; age++){
1.235     brouard  7182:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  7183:        sumnewp[cptcod]=0.;
                   7184:        sumnewm[cptcod]=0.;
                   7185:        for (i=1; i<=nlstate;i++){
                   7186:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   7187:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7188:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   7189:        }
                   7190:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   7191:      }
                   7192:      /* printf("\n"); */
                   7193:      /* } */
                   7194:      /* brutal averaging */
                   7195:      for (i=1; i<=nlstate;i++){
                   7196:        for (age=1; age<=bage; age++){
                   7197:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7198:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7199:        }       
                   7200:        for (age=fage; age<=AGESUP; age++){
                   7201:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7202:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7203:        }
                   7204:      } /* end i status */
                   7205:      for (i=nlstate+1; i<=nlstate+ndeath;i++){
                   7206:        for (age=1; age<=AGESUP; age++){
                   7207:         /*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*/
                   7208:         mobaverage[(int)age][i][cptcod]=0.;
                   7209:        }
                   7210:      }
                   7211:    }/* end cptcod */
                   7212:    free_vector(sumnewm,1, ncovcombmax);
                   7213:    free_vector(sumnewp,1, ncovcombmax);
                   7214:    free_vector(agemaxgood,1, ncovcombmax);
                   7215:    free_vector(agemingood,1, ncovcombmax);
                   7216:    return 0;
                   7217:  }/* End movingaverage */
1.218     brouard  7218:  
1.126     brouard  7219: 
                   7220: /************** Forecasting ******************/
1.235     brouard  7221:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  7222:   /* proj1, year, month, day of starting projection 
                   7223:      agemin, agemax range of age
                   7224:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   7225:      anproj2 year of en of projection (same day and month as proj1).
                   7226:   */
1.235     brouard  7227:    int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  7228:   double agec; /* generic age */
                   7229:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   7230:   double *popeffectif,*popcount;
                   7231:   double ***p3mat;
1.218     brouard  7232:   /* double ***mobaverage; */
1.126     brouard  7233:   char fileresf[FILENAMELENGTH];
                   7234: 
                   7235:   agelim=AGESUP;
1.211     brouard  7236:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   7237:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   7238:      We still use firstpass and lastpass as another selection.
                   7239:   */
1.214     brouard  7240:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   7241:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  7242:  
1.201     brouard  7243:   strcpy(fileresf,"F_"); 
                   7244:   strcat(fileresf,fileresu);
1.126     brouard  7245:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   7246:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   7247:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   7248:   }
1.235     brouard  7249:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   7250:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  7251: 
1.225     brouard  7252:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  7253: 
                   7254: 
                   7255:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   7256:   if (stepm<=12) stepsize=1;
                   7257:   if(estepm < stepm){
                   7258:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   7259:   }
                   7260:   else  hstepm=estepm;   
                   7261: 
                   7262:   hstepm=hstepm/stepm; 
                   7263:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   7264:                                fractional in yp1 */
                   7265:   anprojmean=yp;
                   7266:   yp2=modf((yp1*12),&yp);
                   7267:   mprojmean=yp;
                   7268:   yp1=modf((yp2*30.5),&yp);
                   7269:   jprojmean=yp;
                   7270:   if(jprojmean==0) jprojmean=1;
                   7271:   if(mprojmean==0) jprojmean=1;
                   7272: 
1.227     brouard  7273:   i1=pow(2,cptcoveff);
1.126     brouard  7274:   if (cptcovn < 1){i1=1;}
                   7275:   
                   7276:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   7277:   
                   7278:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  7279:   
1.126     brouard  7280: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  7281:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7282:   for(k=1; k<=i1;k++){
                   7283:     if(TKresult[nres]!= k)
                   7284:       continue;
1.227     brouard  7285:     if(invalidvarcomb[k]){
                   7286:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   7287:       continue;
                   7288:     }
                   7289:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   7290:     for(j=1;j<=cptcoveff;j++) {
                   7291:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7292:     }
1.235     brouard  7293:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7294:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  7295:     }
1.227     brouard  7296:     fprintf(ficresf," yearproj age");
                   7297:     for(j=1; j<=nlstate+ndeath;j++){ 
                   7298:       for(i=1; i<=nlstate;i++)               
                   7299:        fprintf(ficresf," p%d%d",i,j);
                   7300:       fprintf(ficresf," wp.%d",j);
                   7301:     }
                   7302:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   7303:       fprintf(ficresf,"\n");
                   7304:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
                   7305:       for (agec=fage; agec>=(ageminpar-1); agec--){ 
                   7306:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   7307:        nhstepm = nhstepm/hstepm; 
                   7308:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7309:        oldm=oldms;savm=savms;
1.235     brouard  7310:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.227     brouard  7311:        
                   7312:        for (h=0; h<=nhstepm; h++){
                   7313:          if (h*hstepm/YEARM*stepm ==yearp) {
                   7314:            fprintf(ficresf,"\n");
                   7315:            for(j=1;j<=cptcoveff;j++) 
                   7316:              fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7317:            fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   7318:          } 
                   7319:          for(j=1; j<=nlstate+ndeath;j++) {
                   7320:            ppij=0.;
                   7321:            for(i=1; i<=nlstate;i++) {
                   7322:              if (mobilav==1) 
                   7323:                ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][k];
                   7324:              else {
                   7325:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   7326:              }
                   7327:              if (h*hstepm/YEARM*stepm== yearp) {
                   7328:                fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   7329:              }
                   7330:            } /* end i */
                   7331:            if (h*hstepm/YEARM*stepm==yearp) {
                   7332:              fprintf(ficresf," %.3f", ppij);
                   7333:            }
                   7334:          }/* end j */
                   7335:        } /* end h */
                   7336:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7337:       } /* end agec */
                   7338:     } /* end yearp */
                   7339:   } /* end  k */
1.219     brouard  7340:        
1.126     brouard  7341:   fclose(ficresf);
1.215     brouard  7342:   printf("End of Computing forecasting \n");
                   7343:   fprintf(ficlog,"End of Computing forecasting\n");
                   7344: 
1.126     brouard  7345: }
                   7346: 
1.218     brouard  7347: /* /\************** Back Forecasting ******************\/ */
1.225     brouard  7348: /* void prevbackforecast(char fileres[], double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
1.218     brouard  7349: /*   /\* back1, year, month, day of starting backection  */
                   7350: /*      agemin, agemax range of age */
                   7351: /*      dateprev1 dateprev2 range of dates during which prevalence is computed */
                   7352: /*      anback2 year of en of backection (same day and month as back1). */
                   7353: /*   *\/ */
                   7354: /*   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1; */
                   7355: /*   double agec; /\* generic age *\/ */
                   7356: /*   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean; */
                   7357: /*   double *popeffectif,*popcount; */
                   7358: /*   double ***p3mat; */
                   7359: /*   /\* double ***mobaverage; *\/ */
                   7360: /*   char fileresfb[FILENAMELENGTH]; */
                   7361:        
                   7362: /*   agelim=AGESUP; */
                   7363: /*   /\* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people */
                   7364: /*      in each health status at the date of interview (if between dateprev1 and dateprev2). */
                   7365: /*      We still use firstpass and lastpass as another selection. */
                   7366: /*   *\/ */
                   7367: /*   /\* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ *\/ */
                   7368: /*   /\*             firstpass, lastpass,  stepm,  weightopt, model); *\/ */
                   7369: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   7370:        
                   7371: /*   strcpy(fileresfb,"FB_");  */
                   7372: /*   strcat(fileresfb,fileresu); */
                   7373: /*   if((ficresfb=fopen(fileresfb,"w"))==NULL) { */
                   7374: /*     printf("Problem with back forecast resultfile: %s\n", fileresfb); */
                   7375: /*     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb); */
                   7376: /*   } */
                   7377: /*   printf("Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7378: /*   fprintf(ficlog,"Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7379:        
1.225     brouard  7380: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.218     brouard  7381:        
                   7382: /*   /\* if (mobilav!=0) { *\/ */
                   7383: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7384: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7385: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7386: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7387: /*   /\*   } *\/ */
                   7388: /*   /\* } *\/ */
                   7389:        
                   7390: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7391: /*   if (stepm<=12) stepsize=1; */
                   7392: /*   if(estepm < stepm){ */
                   7393: /*     printf ("Problem %d lower than %d\n",estepm, stepm); */
                   7394: /*   } */
                   7395: /*   else  hstepm=estepm;    */
                   7396:        
                   7397: /*   hstepm=hstepm/stepm;  */
                   7398: /*   yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   7399: /*                                fractional in yp1 *\/ */
                   7400: /*   anprojmean=yp; */
                   7401: /*   yp2=modf((yp1*12),&yp); */
                   7402: /*   mprojmean=yp; */
                   7403: /*   yp1=modf((yp2*30.5),&yp); */
                   7404: /*   jprojmean=yp; */
                   7405: /*   if(jprojmean==0) jprojmean=1; */
                   7406: /*   if(mprojmean==0) jprojmean=1; */
                   7407:        
1.225     brouard  7408: /*   i1=cptcoveff; */
1.218     brouard  7409: /*   if (cptcovn < 1){i1=1;} */
1.217     brouard  7410:   
1.218     brouard  7411: /*   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);  */
1.217     brouard  7412:   
1.218     brouard  7413: /*   fprintf(ficresfb,"#****** Routine prevbackforecast **\n"); */
                   7414:        
                   7415: /*     /\*           if (h==(int)(YEARM*yearp)){ *\/ */
                   7416: /*   for(cptcov=1, k=0;cptcov<=i1;cptcov++){ */
1.225     brouard  7417: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
1.218     brouard  7418: /*       k=k+1; */
                   7419: /*       fprintf(ficresfb,"\n#****** hbijx=probability over h years, hp.jx is weighted by observed prev \n#"); */
1.225     brouard  7420: /*       for(j=1;j<=cptcoveff;j++) { */
1.218     brouard  7421: /*                             fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7422: /*       } */
                   7423: /*       fprintf(ficresfb," yearbproj age"); */
                   7424: /*       for(j=1; j<=nlstate+ndeath;j++){  */
                   7425: /*                             for(i=1; i<=nlstate;i++)               */
                   7426: /*           fprintf(ficresfb," p%d%d",i,j); */
                   7427: /*                             fprintf(ficresfb," p.%d",j); */
                   7428: /*       } */
                   7429: /*       for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {  */
                   7430: /*                             /\* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  *\/ */
                   7431: /*                             fprintf(ficresfb,"\n"); */
                   7432: /*                             fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);    */
                   7433: /*                             for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   7434: /*                                     nhstepm=(int) rint((agelim-agec)*YEARM/stepm);  */
                   7435: /*                                     nhstepm = nhstepm/hstepm;  */
                   7436: /*                                     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7437: /*                                     oldm=oldms;savm=savms; */
                   7438: /*                                     hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm,oldm,savm, dnewm, doldm, dsavm, k);       */
                   7439: /*                                     for (h=0; h<=nhstepm; h++){ */
                   7440: /*                                             if (h*hstepm/YEARM*stepm ==yearp) { */
                   7441: /*               fprintf(ficresfb,"\n"); */
1.225     brouard  7442: /*               for(j=1;j<=cptcoveff;j++)  */
1.218     brouard  7443: /*                 fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7444: /*                                                     fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec+h*hstepm/YEARM*stepm); */
                   7445: /*                                             }  */
                   7446: /*                                             for(j=1; j<=nlstate+ndeath;j++) { */
                   7447: /*                                                     ppij=0.; */
                   7448: /*                                                     for(i=1; i<=nlstate;i++) { */
                   7449: /*                                                             if (mobilav==1)  */
                   7450: /*                                                                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod]; */
                   7451: /*                                                             else { */
                   7452: /*                                                                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod]; */
                   7453: /*                                                             } */
                   7454: /*                                                             if (h*hstepm/YEARM*stepm== yearp) { */
                   7455: /*                                                                     fprintf(ficresfb," %.3f", p3mat[i][j][h]); */
                   7456: /*                                                             } */
                   7457: /*                                                     } /\* end i *\/ */
                   7458: /*                                                     if (h*hstepm/YEARM*stepm==yearp) { */
                   7459: /*                                                             fprintf(ficresfb," %.3f", ppij); */
                   7460: /*                                                     } */
                   7461: /*                                             }/\* end j *\/ */
                   7462: /*                                     } /\* end h *\/ */
                   7463: /*                                     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7464: /*                             } /\* end agec *\/ */
                   7465: /*       } /\* end yearp *\/ */
                   7466: /*     } /\* end cptcod *\/ */
                   7467: /*   } /\* end  cptcov *\/ */
                   7468:        
                   7469: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7470:        
                   7471: /*   fclose(ficresfb); */
                   7472: /*   printf("End of Computing Back forecasting \n"); */
                   7473: /*   fprintf(ficlog,"End of Computing Back forecasting\n"); */
1.217     brouard  7474:        
1.218     brouard  7475: /* } */
1.217     brouard  7476: 
1.126     brouard  7477: /************** Forecasting *****not tested NB*************/
1.227     brouard  7478: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  7479:   
1.227     brouard  7480: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   7481: /*   int *popage; */
                   7482: /*   double calagedatem, agelim, kk1, kk2; */
                   7483: /*   double *popeffectif,*popcount; */
                   7484: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   7485: /*   /\* double ***mobaverage; *\/ */
                   7486: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  7487: 
1.227     brouard  7488: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7489: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7490: /*   agelim=AGESUP; */
                   7491: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  7492:   
1.227     brouard  7493: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  7494:   
                   7495:   
1.227     brouard  7496: /*   strcpy(filerespop,"POP_");  */
                   7497: /*   strcat(filerespop,fileresu); */
                   7498: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   7499: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   7500: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   7501: /*   } */
                   7502: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   7503: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  7504: 
1.227     brouard  7505: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  7506: 
1.227     brouard  7507: /*   /\* if (mobilav!=0) { *\/ */
                   7508: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7509: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7510: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7511: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7512: /*   /\*   } *\/ */
                   7513: /*   /\* } *\/ */
1.126     brouard  7514: 
1.227     brouard  7515: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7516: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  7517:   
1.227     brouard  7518: /*   agelim=AGESUP; */
1.126     brouard  7519:   
1.227     brouard  7520: /*   hstepm=1; */
                   7521: /*   hstepm=hstepm/stepm;  */
1.218     brouard  7522:        
1.227     brouard  7523: /*   if (popforecast==1) { */
                   7524: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   7525: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   7526: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   7527: /*     }  */
                   7528: /*     popage=ivector(0,AGESUP); */
                   7529: /*     popeffectif=vector(0,AGESUP); */
                   7530: /*     popcount=vector(0,AGESUP); */
1.126     brouard  7531:     
1.227     brouard  7532: /*     i=1;    */
                   7533: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  7534:     
1.227     brouard  7535: /*     imx=i; */
                   7536: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   7537: /*   } */
1.218     brouard  7538:   
1.227     brouard  7539: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   7540: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   7541: /*       k=k+1; */
                   7542: /*       fprintf(ficrespop,"\n#******"); */
                   7543: /*       for(j=1;j<=cptcoveff;j++) { */
                   7544: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7545: /*       } */
                   7546: /*       fprintf(ficrespop,"******\n"); */
                   7547: /*       fprintf(ficrespop,"# Age"); */
                   7548: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   7549: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  7550:       
1.227     brouard  7551: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   7552: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  7553:        
1.227     brouard  7554: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7555: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7556: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7557:          
1.227     brouard  7558: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7559: /*       oldm=oldms;savm=savms; */
                   7560: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  7561:          
1.227     brouard  7562: /*       for (h=0; h<=nhstepm; h++){ */
                   7563: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7564: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7565: /*         }  */
                   7566: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7567: /*           kk1=0.;kk2=0; */
                   7568: /*           for(i=1; i<=nlstate;i++) {               */
                   7569: /*             if (mobilav==1)  */
                   7570: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   7571: /*             else { */
                   7572: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   7573: /*             } */
                   7574: /*           } */
                   7575: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   7576: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   7577: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   7578: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   7579: /*           } */
                   7580: /*         } */
                   7581: /*         for(i=1; i<=nlstate;i++){ */
                   7582: /*           kk1=0.; */
                   7583: /*           for(j=1; j<=nlstate;j++){ */
                   7584: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   7585: /*           } */
                   7586: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   7587: /*         } */
1.218     brouard  7588:            
1.227     brouard  7589: /*         if (h==(int)(calagedatem+12*cpt)) */
                   7590: /*           for(j=1; j<=nlstate;j++)  */
                   7591: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   7592: /*       } */
                   7593: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7594: /*     } */
                   7595: /*       } */
1.218     brouard  7596:       
1.227     brouard  7597: /*       /\******\/ */
1.218     brouard  7598:       
1.227     brouard  7599: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   7600: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   7601: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7602: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7603: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7604:          
1.227     brouard  7605: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7606: /*       oldm=oldms;savm=savms; */
                   7607: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   7608: /*       for (h=0; h<=nhstepm; h++){ */
                   7609: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7610: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7611: /*         }  */
                   7612: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7613: /*           kk1=0.;kk2=0; */
                   7614: /*           for(i=1; i<=nlstate;i++) {               */
                   7615: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   7616: /*           } */
                   7617: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   7618: /*         } */
                   7619: /*       } */
                   7620: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7621: /*     } */
                   7622: /*       } */
                   7623: /*     }  */
                   7624: /*   } */
1.218     brouard  7625:   
1.227     brouard  7626: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  7627:   
1.227     brouard  7628: /*   if (popforecast==1) { */
                   7629: /*     free_ivector(popage,0,AGESUP); */
                   7630: /*     free_vector(popeffectif,0,AGESUP); */
                   7631: /*     free_vector(popcount,0,AGESUP); */
                   7632: /*   } */
                   7633: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7634: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7635: /*   fclose(ficrespop); */
                   7636: /* } /\* End of popforecast *\/ */
1.218     brouard  7637:  
1.126     brouard  7638: int fileappend(FILE *fichier, char *optionfich)
                   7639: {
                   7640:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   7641:     printf("Problem with file: %s\n", optionfich);
                   7642:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   7643:     return (0);
                   7644:   }
                   7645:   fflush(fichier);
                   7646:   return (1);
                   7647: }
                   7648: 
                   7649: 
                   7650: /**************** function prwizard **********************/
                   7651: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   7652: {
                   7653: 
                   7654:   /* Wizard to print covariance matrix template */
                   7655: 
1.164     brouard  7656:   char ca[32], cb[32];
                   7657:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  7658:   int numlinepar;
                   7659: 
                   7660:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7661:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7662:   for(i=1; i <=nlstate; i++){
                   7663:     jj=0;
                   7664:     for(j=1; j <=nlstate+ndeath; j++){
                   7665:       if(j==i) continue;
                   7666:       jj++;
                   7667:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   7668:       printf("%1d%1d",i,j);
                   7669:       fprintf(ficparo,"%1d%1d",i,j);
                   7670:       for(k=1; k<=ncovmodel;k++){
                   7671:        /*        printf(" %lf",param[i][j][k]); */
                   7672:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   7673:        printf(" 0.");
                   7674:        fprintf(ficparo," 0.");
                   7675:       }
                   7676:       printf("\n");
                   7677:       fprintf(ficparo,"\n");
                   7678:     }
                   7679:   }
                   7680:   printf("# Scales (for hessian or gradient estimation)\n");
                   7681:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   7682:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   7683:   for(i=1; i <=nlstate; i++){
                   7684:     jj=0;
                   7685:     for(j=1; j <=nlstate+ndeath; j++){
                   7686:       if(j==i) continue;
                   7687:       jj++;
                   7688:       fprintf(ficparo,"%1d%1d",i,j);
                   7689:       printf("%1d%1d",i,j);
                   7690:       fflush(stdout);
                   7691:       for(k=1; k<=ncovmodel;k++){
                   7692:        /*      printf(" %le",delti3[i][j][k]); */
                   7693:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   7694:        printf(" 0.");
                   7695:        fprintf(ficparo," 0.");
                   7696:       }
                   7697:       numlinepar++;
                   7698:       printf("\n");
                   7699:       fprintf(ficparo,"\n");
                   7700:     }
                   7701:   }
                   7702:   printf("# Covariance matrix\n");
                   7703: /* # 121 Var(a12)\n\ */
                   7704: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7705: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   7706: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   7707: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   7708: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   7709: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   7710: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   7711:   fflush(stdout);
                   7712:   fprintf(ficparo,"# Covariance matrix\n");
                   7713:   /* # 121 Var(a12)\n\ */
                   7714:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7715:   /* #   ...\n\ */
                   7716:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   7717:   
                   7718:   for(itimes=1;itimes<=2;itimes++){
                   7719:     jj=0;
                   7720:     for(i=1; i <=nlstate; i++){
                   7721:       for(j=1; j <=nlstate+ndeath; j++){
                   7722:        if(j==i) continue;
                   7723:        for(k=1; k<=ncovmodel;k++){
                   7724:          jj++;
                   7725:          ca[0]= k+'a'-1;ca[1]='\0';
                   7726:          if(itimes==1){
                   7727:            printf("#%1d%1d%d",i,j,k);
                   7728:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   7729:          }else{
                   7730:            printf("%1d%1d%d",i,j,k);
                   7731:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   7732:            /*  printf(" %.5le",matcov[i][j]); */
                   7733:          }
                   7734:          ll=0;
                   7735:          for(li=1;li <=nlstate; li++){
                   7736:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   7737:              if(lj==li) continue;
                   7738:              for(lk=1;lk<=ncovmodel;lk++){
                   7739:                ll++;
                   7740:                if(ll<=jj){
                   7741:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   7742:                  if(ll<jj){
                   7743:                    if(itimes==1){
                   7744:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7745:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7746:                    }else{
                   7747:                      printf(" 0.");
                   7748:                      fprintf(ficparo," 0.");
                   7749:                    }
                   7750:                  }else{
                   7751:                    if(itimes==1){
                   7752:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   7753:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   7754:                    }else{
                   7755:                      printf(" 0.");
                   7756:                      fprintf(ficparo," 0.");
                   7757:                    }
                   7758:                  }
                   7759:                }
                   7760:              } /* end lk */
                   7761:            } /* end lj */
                   7762:          } /* end li */
                   7763:          printf("\n");
                   7764:          fprintf(ficparo,"\n");
                   7765:          numlinepar++;
                   7766:        } /* end k*/
                   7767:       } /*end j */
                   7768:     } /* end i */
                   7769:   } /* end itimes */
                   7770: 
                   7771: } /* end of prwizard */
                   7772: /******************* Gompertz Likelihood ******************************/
                   7773: double gompertz(double x[])
                   7774: { 
                   7775:   double A,B,L=0.0,sump=0.,num=0.;
                   7776:   int i,n=0; /* n is the size of the sample */
                   7777: 
1.220     brouard  7778:   for (i=1;i<=imx ; i++) {
1.126     brouard  7779:     sump=sump+weight[i];
                   7780:     /*    sump=sump+1;*/
                   7781:     num=num+1;
                   7782:   }
                   7783:  
                   7784:  
                   7785:   /* for (i=0; i<=imx; i++) 
                   7786:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   7787: 
                   7788:   for (i=1;i<=imx ; i++)
                   7789:     {
                   7790:       if (cens[i] == 1 && wav[i]>1)
                   7791:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   7792:       
                   7793:       if (cens[i] == 0 && wav[i]>1)
                   7794:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   7795:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   7796:       
                   7797:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   7798:       if (wav[i] > 1 ) { /* ??? */
                   7799:        L=L+A*weight[i];
                   7800:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   7801:       }
                   7802:     }
                   7803: 
                   7804:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   7805:  
                   7806:   return -2*L*num/sump;
                   7807: }
                   7808: 
1.136     brouard  7809: #ifdef GSL
                   7810: /******************* Gompertz_f Likelihood ******************************/
                   7811: double gompertz_f(const gsl_vector *v, void *params)
                   7812: { 
                   7813:   double A,B,LL=0.0,sump=0.,num=0.;
                   7814:   double *x= (double *) v->data;
                   7815:   int i,n=0; /* n is the size of the sample */
                   7816: 
                   7817:   for (i=0;i<=imx-1 ; i++) {
                   7818:     sump=sump+weight[i];
                   7819:     /*    sump=sump+1;*/
                   7820:     num=num+1;
                   7821:   }
                   7822:  
                   7823:  
                   7824:   /* for (i=0; i<=imx; i++) 
                   7825:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   7826:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   7827:   for (i=1;i<=imx ; i++)
                   7828:     {
                   7829:       if (cens[i] == 1 && wav[i]>1)
                   7830:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   7831:       
                   7832:       if (cens[i] == 0 && wav[i]>1)
                   7833:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   7834:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   7835:       
                   7836:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   7837:       if (wav[i] > 1 ) { /* ??? */
                   7838:        LL=LL+A*weight[i];
                   7839:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   7840:       }
                   7841:     }
                   7842: 
                   7843:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   7844:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   7845:  
                   7846:   return -2*LL*num/sump;
                   7847: }
                   7848: #endif
                   7849: 
1.126     brouard  7850: /******************* Printing html file ***********/
1.201     brouard  7851: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  7852:                  int lastpass, int stepm, int weightopt, char model[],\
                   7853:                  int imx,  double p[],double **matcov,double agemortsup){
                   7854:   int i,k;
                   7855: 
                   7856:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   7857:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   7858:   for (i=1;i<=2;i++) 
                   7859:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  7860:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  7861:   fprintf(fichtm,"</ul>");
                   7862: 
                   7863: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   7864: 
                   7865:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   7866: 
                   7867:  for (k=agegomp;k<(agemortsup-2);k++) 
                   7868:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   7869: 
                   7870:  
                   7871:   fflush(fichtm);
                   7872: }
                   7873: 
                   7874: /******************* Gnuplot file **************/
1.201     brouard  7875: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  7876: 
                   7877:   char dirfileres[132],optfileres[132];
1.164     brouard  7878: 
1.126     brouard  7879:   int ng;
                   7880: 
                   7881: 
                   7882:   /*#ifdef windows */
                   7883:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   7884:     /*#endif */
                   7885: 
                   7886: 
                   7887:   strcpy(dirfileres,optionfilefiname);
                   7888:   strcpy(optfileres,"vpl");
1.199     brouard  7889:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  7890:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  7891:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  7892:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  7893:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   7894: 
                   7895: } 
                   7896: 
1.136     brouard  7897: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   7898: {
1.126     brouard  7899: 
1.136     brouard  7900:   /*-------- data file ----------*/
                   7901:   FILE *fic;
                   7902:   char dummy[]="                         ";
1.240     brouard  7903:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  7904:   int lstra;
1.136     brouard  7905:   int linei, month, year,iout;
                   7906:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  7907:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  7908:   char *stratrunc;
1.223     brouard  7909: 
1.240     brouard  7910:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   7911:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  7912: 
1.240     brouard  7913:   for(v=1; v <=ncovcol;v++){
                   7914:     DummyV[v]=0;
                   7915:     FixedV[v]=0;
                   7916:   }
                   7917:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   7918:     DummyV[v]=1;
                   7919:     FixedV[v]=0;
                   7920:   }
                   7921:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   7922:     DummyV[v]=0;
                   7923:     FixedV[v]=1;
                   7924:   }
                   7925:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   7926:     DummyV[v]=1;
                   7927:     FixedV[v]=1;
                   7928:   }
                   7929:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   7930:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   7931:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   7932:   }
1.126     brouard  7933: 
1.136     brouard  7934:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  7935:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   7936:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  7937:   }
1.126     brouard  7938: 
1.136     brouard  7939:   i=1;
                   7940:   linei=0;
                   7941:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   7942:     linei=linei+1;
                   7943:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   7944:       if(line[j] == '\t')
                   7945:        line[j] = ' ';
                   7946:     }
                   7947:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   7948:       ;
                   7949:     };
                   7950:     line[j+1]=0;  /* Trims blanks at end of line */
                   7951:     if(line[0]=='#'){
                   7952:       fprintf(ficlog,"Comment line\n%s\n",line);
                   7953:       printf("Comment line\n%s\n",line);
                   7954:       continue;
                   7955:     }
                   7956:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  7957:     strcpy(line, linetmp);
1.223     brouard  7958:     
                   7959:     /* Loops on waves */
                   7960:     for (j=maxwav;j>=1;j--){
                   7961:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  7962:        cutv(stra, strb, line, ' '); 
                   7963:        if(strb[0]=='.') { /* Missing value */
                   7964:          lval=-1;
                   7965:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   7966:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   7967:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   7968:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   7969:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   7970:            return 1;
                   7971:          }
                   7972:        }else{
                   7973:          errno=0;
                   7974:          /* what_kind_of_number(strb); */
                   7975:          dval=strtod(strb,&endptr); 
                   7976:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   7977:          /* if(strb != endptr && *endptr == '\0') */
                   7978:          /*    dval=dlval; */
                   7979:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   7980:          if( strb[0]=='\0' || (*endptr != '\0')){
                   7981:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   7982:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   7983:            return 1;
                   7984:          }
                   7985:          cotqvar[j][iv][i]=dval; 
                   7986:          cotvar[j][ntv+iv][i]=dval; 
                   7987:        }
                   7988:        strcpy(line,stra);
1.223     brouard  7989:       }/* end loop ntqv */
1.225     brouard  7990:       
1.223     brouard  7991:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  7992:        cutv(stra, strb, line, ' '); 
                   7993:        if(strb[0]=='.') { /* Missing value */
                   7994:          lval=-1;
                   7995:        }else{
                   7996:          errno=0;
                   7997:          lval=strtol(strb,&endptr,10); 
                   7998:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   7999:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8000:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   8001:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   8002:            return 1;
                   8003:          }
                   8004:        }
                   8005:        if(lval <-1 || lval >1){
                   8006:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8007:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8008:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8009:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8010:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8011:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8012:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8013:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8014:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  8015:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8016:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8017:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8018:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8019:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8020:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8021:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8022:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8023:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  8024:          return 1;
                   8025:        }
                   8026:        cotvar[j][iv][i]=(double)(lval);
                   8027:        strcpy(line,stra);
1.223     brouard  8028:       }/* end loop ntv */
1.225     brouard  8029:       
1.223     brouard  8030:       /* Statuses  at wave */
1.137     brouard  8031:       cutv(stra, strb, line, ' '); 
1.223     brouard  8032:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  8033:        lval=-1;
1.136     brouard  8034:       }else{
1.238     brouard  8035:        errno=0;
                   8036:        lval=strtol(strb,&endptr,10); 
                   8037:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8038:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8039:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   8040:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   8041:          return 1;
                   8042:        }
1.136     brouard  8043:       }
1.225     brouard  8044:       
1.136     brouard  8045:       s[j][i]=lval;
1.225     brouard  8046:       
1.223     brouard  8047:       /* Date of Interview */
1.136     brouard  8048:       strcpy(line,stra);
                   8049:       cutv(stra, strb,line,' ');
1.169     brouard  8050:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8051:       }
1.169     brouard  8052:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  8053:        month=99;
                   8054:        year=9999;
1.136     brouard  8055:       }else{
1.225     brouard  8056:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   8057:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   8058:        return 1;
1.136     brouard  8059:       }
                   8060:       anint[j][i]= (double) year; 
                   8061:       mint[j][i]= (double)month; 
                   8062:       strcpy(line,stra);
1.223     brouard  8063:     } /* End loop on waves */
1.225     brouard  8064:     
1.223     brouard  8065:     /* Date of death */
1.136     brouard  8066:     cutv(stra, strb,line,' '); 
1.169     brouard  8067:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8068:     }
1.169     brouard  8069:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  8070:       month=99;
                   8071:       year=9999;
                   8072:     }else{
1.141     brouard  8073:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  8074:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   8075:       return 1;
1.136     brouard  8076:     }
                   8077:     andc[i]=(double) year; 
                   8078:     moisdc[i]=(double) month; 
                   8079:     strcpy(line,stra);
                   8080:     
1.223     brouard  8081:     /* Date of birth */
1.136     brouard  8082:     cutv(stra, strb,line,' '); 
1.169     brouard  8083:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8084:     }
1.169     brouard  8085:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  8086:       month=99;
                   8087:       year=9999;
                   8088:     }else{
1.141     brouard  8089:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   8090:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8091:       return 1;
1.136     brouard  8092:     }
                   8093:     if (year==9999) {
1.141     brouard  8094:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   8095:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8096:       return 1;
                   8097:       
1.136     brouard  8098:     }
                   8099:     annais[i]=(double)(year);
                   8100:     moisnais[i]=(double)(month); 
                   8101:     strcpy(line,stra);
1.225     brouard  8102:     
1.223     brouard  8103:     /* Sample weight */
1.136     brouard  8104:     cutv(stra, strb,line,' '); 
                   8105:     errno=0;
                   8106:     dval=strtod(strb,&endptr); 
                   8107:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  8108:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   8109:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  8110:       fflush(ficlog);
                   8111:       return 1;
                   8112:     }
                   8113:     weight[i]=dval; 
                   8114:     strcpy(line,stra);
1.225     brouard  8115:     
1.223     brouard  8116:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   8117:       cutv(stra, strb, line, ' '); 
                   8118:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  8119:        lval=-1;
1.223     brouard  8120:       }else{
1.225     brouard  8121:        errno=0;
                   8122:        /* what_kind_of_number(strb); */
                   8123:        dval=strtod(strb,&endptr);
                   8124:        /* if(strb != endptr && *endptr == '\0') */
                   8125:        /*   dval=dlval; */
                   8126:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8127:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8128:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   8129:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   8130:          return 1;
                   8131:        }
                   8132:        coqvar[iv][i]=dval; 
1.226     brouard  8133:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  8134:       }
                   8135:       strcpy(line,stra);
                   8136:     }/* end loop nqv */
1.136     brouard  8137:     
1.223     brouard  8138:     /* Covariate values */
1.136     brouard  8139:     for (j=ncovcol;j>=1;j--){
                   8140:       cutv(stra, strb,line,' '); 
1.223     brouard  8141:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  8142:        lval=-1;
1.136     brouard  8143:       }else{
1.225     brouard  8144:        errno=0;
                   8145:        lval=strtol(strb,&endptr,10); 
                   8146:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8147:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   8148:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   8149:          return 1;
                   8150:        }
1.136     brouard  8151:       }
                   8152:       if(lval <-1 || lval >1){
1.225     brouard  8153:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8154:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8155:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8156:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8157:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8158:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8159:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8160:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8161:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  8162:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8163:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8164:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8165:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8166:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8167:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8168:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8169:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8170:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  8171:        return 1;
1.136     brouard  8172:       }
                   8173:       covar[j][i]=(double)(lval);
                   8174:       strcpy(line,stra);
                   8175:     }  
                   8176:     lstra=strlen(stra);
1.225     brouard  8177:     
1.136     brouard  8178:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   8179:       stratrunc = &(stra[lstra-9]);
                   8180:       num[i]=atol(stratrunc);
                   8181:     }
                   8182:     else
                   8183:       num[i]=atol(stra);
                   8184:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   8185:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   8186:     
                   8187:     i=i+1;
                   8188:   } /* End loop reading  data */
1.225     brouard  8189:   
1.136     brouard  8190:   *imax=i-1; /* Number of individuals */
                   8191:   fclose(fic);
1.225     brouard  8192:   
1.136     brouard  8193:   return (0);
1.164     brouard  8194:   /* endread: */
1.225     brouard  8195:   printf("Exiting readdata: ");
                   8196:   fclose(fic);
                   8197:   return (1);
1.223     brouard  8198: }
1.126     brouard  8199: 
1.234     brouard  8200: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  8201:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  8202:   while (*p2 == ' ')
1.234     brouard  8203:     p2++; 
                   8204:   /* while ((*p1++ = *p2++) !=0) */
                   8205:   /*   ; */
                   8206:   /* do */
                   8207:   /*   while (*p2 == ' ') */
                   8208:   /*     p2++; */
                   8209:   /* while (*p1++ == *p2++); */
                   8210:   *stri=p2; 
1.145     brouard  8211: }
                   8212: 
1.235     brouard  8213: int decoderesult ( char resultline[], int nres)
1.230     brouard  8214: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   8215: {
1.235     brouard  8216:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  8217:   char resultsav[MAXLINE];
1.234     brouard  8218:   int resultmodel[MAXLINE];
                   8219:   int modelresult[MAXLINE];
1.230     brouard  8220:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   8221: 
1.234     brouard  8222:   removefirstspace(&resultline);
1.233     brouard  8223:   printf("decoderesult:%s\n",resultline);
1.230     brouard  8224: 
                   8225:   if (strstr(resultline,"v") !=0){
                   8226:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   8227:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   8228:     return 1;
                   8229:   }
                   8230:   trimbb(resultsav, resultline);
                   8231:   if (strlen(resultsav) >1){
                   8232:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   8233:   }
1.234     brouard  8234:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   8235:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8236:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8237:   }
                   8238:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   8239:     if(nbocc(resultsav,'=') >1){
                   8240:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   8241:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   8242:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   8243:     }else
                   8244:       cutl(strc,strd,resultsav,'=');
1.230     brouard  8245:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  8246:     
1.230     brouard  8247:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   8248:     Tvarsel[k]=atoi(strc);
                   8249:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   8250:     /* cptcovsel++;     */
                   8251:     if (nbocc(stra,'=') >0)
                   8252:       strcpy(resultsav,stra); /* and analyzes it */
                   8253:   }
1.235     brouard  8254:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  8255:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8256:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  8257:       match=0;
1.236     brouard  8258:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  8259:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  8260:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  8261:          match=1;
                   8262:          break;
                   8263:        }
                   8264:       }
                   8265:       if(match == 0){
                   8266:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8267:       }
                   8268:     }
                   8269:   }
1.235     brouard  8270:   /* Checking for missing or useless values in comparison of current model needs */
                   8271:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  8272:     match=0;
1.235     brouard  8273:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8274:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  8275:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  8276:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  8277:          ++match;
                   8278:        }
                   8279:       }
                   8280:     }
                   8281:     if(match == 0){
                   8282:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8283:     }else if(match > 1){
                   8284:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   8285:     }
                   8286:   }
1.235     brouard  8287:       
1.234     brouard  8288:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  8289:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8290:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   8291:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   8292:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   8293:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   8294:   /*    1 0 0 0 */
                   8295:   /*    2 1 0 0 */
                   8296:   /*    3 0 1 0 */ 
                   8297:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   8298:   /*    5 0 0 1 */
                   8299:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   8300:   /*    7 0 1 1 */
                   8301:   /*    8 1 1 1 */
1.237     brouard  8302:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   8303:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   8304:   /* V5*age V5 known which value for nres?  */
                   8305:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  8306:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   8307:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  8308:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  8309:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   8310:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  8311:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   8312:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   8313:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  8314:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   8315:       k4++;;
                   8316:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   8317:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   8318:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  8319:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   8320:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   8321:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  8322:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   8323:       k4q++;;
                   8324:     }
                   8325:   }
1.234     brouard  8326:   
1.235     brouard  8327:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  8328:   return (0);
                   8329: }
1.235     brouard  8330: 
1.230     brouard  8331: int decodemodel( char model[], int lastobs)
                   8332:  /**< This routine decodes the model and returns:
1.224     brouard  8333:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   8334:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   8335:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   8336:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   8337:        * - cptcovage number of covariates with age*products =2
                   8338:        * - cptcovs number of simple covariates
                   8339:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   8340:        *     which is a new column after the 9 (ncovcol) variables. 
                   8341:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   8342:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   8343:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   8344:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   8345:        */
1.136     brouard  8346: {
1.238     brouard  8347:   int i, j, k, ks, v;
1.227     brouard  8348:   int  j1, k1, k2, k3, k4;
1.136     brouard  8349:   char modelsav[80];
1.145     brouard  8350:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  8351:   char *strpt;
1.136     brouard  8352: 
1.145     brouard  8353:   /*removespace(model);*/
1.136     brouard  8354:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  8355:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  8356:     if (strstr(model,"AGE") !=0){
1.192     brouard  8357:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   8358:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  8359:       return 1;
                   8360:     }
1.141     brouard  8361:     if (strstr(model,"v") !=0){
                   8362:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   8363:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   8364:       return 1;
                   8365:     }
1.187     brouard  8366:     strcpy(modelsav,model); 
                   8367:     if ((strpt=strstr(model,"age*age")) !=0){
                   8368:       printf(" strpt=%s, model=%s\n",strpt, model);
                   8369:       if(strpt != model){
1.234     brouard  8370:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8371:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8372:  corresponding column of parameters.\n",model);
1.234     brouard  8373:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8374:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8375:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  8376:        return 1;
1.225     brouard  8377:       }
1.187     brouard  8378:       nagesqr=1;
                   8379:       if (strstr(model,"+age*age") !=0)
1.234     brouard  8380:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  8381:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  8382:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  8383:       else 
1.234     brouard  8384:        substrchaine(modelsav, model, "age*age");
1.187     brouard  8385:     }else
                   8386:       nagesqr=0;
                   8387:     if (strlen(modelsav) >1){
                   8388:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   8389:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  8390:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  8391:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  8392:                     * cst, age and age*age 
                   8393:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   8394:       /* including age products which are counted in cptcovage.
                   8395:        * but the covariates which are products must be treated 
                   8396:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  8397:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   8398:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  8399:       
                   8400:       
1.187     brouard  8401:       /*   Design
                   8402:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   8403:        *  <          ncovcol=8                >
                   8404:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   8405:        *   k=  1    2      3       4     5       6      7        8
                   8406:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   8407:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  8408:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   8409:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  8410:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   8411:        *  Tage[++cptcovage]=k
                   8412:        *       if products, new covar are created after ncovcol with k1
                   8413:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   8414:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   8415:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   8416:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   8417:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   8418:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   8419:        *  <          ncovcol=8                >
                   8420:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   8421:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   8422:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   8423:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8424:        * p Tprod[1]@2={                         6, 5}
                   8425:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   8426:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   8427:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   8428:        *How to reorganize?
                   8429:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   8430:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8431:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   8432:        * Struct []
                   8433:        */
1.225     brouard  8434:       
1.187     brouard  8435:       /* This loop fills the array Tvar from the string 'model'.*/
                   8436:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   8437:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   8438:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   8439:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   8440:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   8441:       /*       k=1 Tvar[1]=2 (from V2) */
                   8442:       /*       k=5 Tvar[5] */
                   8443:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  8444:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  8445:       /*       } */
1.198     brouard  8446:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  8447:       /*
                   8448:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  8449:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   8450:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   8451:       }
1.187     brouard  8452:       cptcovage=0;
                   8453:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  8454:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  8455:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  8456:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   8457:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   8458:        /*scanf("%d",i);*/
                   8459:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   8460:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   8461:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   8462:            /* covar is not filled and then is empty */
                   8463:            cptcovprod--;
                   8464:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   8465:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   8466:            Typevar[k]=1;  /* 1 for age product */
                   8467:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   8468:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   8469:            /*printf("stre=%s ", stre);*/
                   8470:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   8471:            cptcovprod--;
                   8472:            cutl(stre,strb,strc,'V');
                   8473:            Tvar[k]=atoi(stre);
                   8474:            Typevar[k]=1;  /* 1 for age product */
                   8475:            cptcovage++;
                   8476:            Tage[cptcovage]=k;
                   8477:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   8478:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   8479:            cptcovn++;
                   8480:            cptcovprodnoage++;k1++;
                   8481:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   8482:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   8483:                                                because this model-covariate is a construction we invent a new column
                   8484:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   8485:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   8486:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   8487:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   8488:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   8489:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   8490:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   8491:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   8492:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   8493:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   8494:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   8495:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  8496:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  8497:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   8498:            for (i=1; i<=lastobs;i++){
                   8499:              /* Computes the new covariate which is a product of
                   8500:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   8501:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   8502:            }
                   8503:          } /* End age is not in the model */
                   8504:        } /* End if model includes a product */
                   8505:        else { /* no more sum */
                   8506:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   8507:          /*  scanf("%d",i);*/
                   8508:          cutl(strd,strc,strb,'V');
                   8509:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   8510:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   8511:          Tvar[k]=atoi(strd);
                   8512:          Typevar[k]=0;  /* 0 for simple covariates */
                   8513:        }
                   8514:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  8515:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  8516:                                  scanf("%d",i);*/
1.187     brouard  8517:       } /* end of loop + on total covariates */
                   8518:     } /* end if strlen(modelsave == 0) age*age might exist */
                   8519:   } /* end if strlen(model == 0) */
1.136     brouard  8520:   
                   8521:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   8522:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  8523:   
1.136     brouard  8524:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  8525:      printf("cptcovprod=%d ", cptcovprod);
                   8526:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   8527:      scanf("%d ",i);*/
                   8528: 
                   8529: 
1.230     brouard  8530: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   8531:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  8532: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   8533:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   8534:    k =           1    2   3     4       5       6      7      8        9
                   8535:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   8536:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  8537:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   8538:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   8539:          Tmodelind[combination of covar]=k;
1.225     brouard  8540: */  
                   8541: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  8542:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  8543:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  8544:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  8545:   printf("Model=%s\n\
                   8546: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8547: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8548: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8549:   fprintf(ficlog,"Model=%s\n\
                   8550: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8551: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8552: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  8553:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  8554:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   8555:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  8556:       Fixed[k]= 0;
                   8557:       Dummy[k]= 0;
1.225     brouard  8558:       ncoveff++;
1.232     brouard  8559:       ncovf++;
1.234     brouard  8560:       nsd++;
                   8561:       modell[k].maintype= FTYPE;
                   8562:       TvarsD[nsd]=Tvar[k];
                   8563:       TvarsDind[nsd]=k;
                   8564:       TvarF[ncovf]=Tvar[k];
                   8565:       TvarFind[ncovf]=k;
                   8566:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8567:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8568:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   8569:       Fixed[k]= 0;
                   8570:       Dummy[k]= 0;
                   8571:       ncoveff++;
                   8572:       ncovf++;
                   8573:       modell[k].maintype= FTYPE;
                   8574:       TvarF[ncovf]=Tvar[k];
                   8575:       TvarFind[ncovf]=k;
1.230     brouard  8576:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  8577:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  8578:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  8579:       Fixed[k]= 0;
                   8580:       Dummy[k]= 1;
1.230     brouard  8581:       nqfveff++;
1.234     brouard  8582:       modell[k].maintype= FTYPE;
                   8583:       modell[k].subtype= FQ;
                   8584:       nsq++;
                   8585:       TvarsQ[nsq]=Tvar[k];
                   8586:       TvarsQind[nsq]=k;
1.232     brouard  8587:       ncovf++;
1.234     brouard  8588:       TvarF[ncovf]=Tvar[k];
                   8589:       TvarFind[ncovf]=k;
1.231     brouard  8590:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  8591:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  8592:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  8593:       Fixed[k]= 1;
                   8594:       Dummy[k]= 0;
1.225     brouard  8595:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  8596:       modell[k].maintype= VTYPE;
                   8597:       modell[k].subtype= VD;
                   8598:       nsd++;
                   8599:       TvarsD[nsd]=Tvar[k];
                   8600:       TvarsDind[nsd]=k;
                   8601:       ncovv++; /* Only simple time varying variables */
                   8602:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8603:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8604:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   8605:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  8606:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   8607:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  8608:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  8609:       Fixed[k]= 1;
                   8610:       Dummy[k]= 1;
                   8611:       nqtveff++;
                   8612:       modell[k].maintype= VTYPE;
                   8613:       modell[k].subtype= VQ;
                   8614:       ncovv++; /* Only simple time varying variables */
                   8615:       nsq++;
                   8616:       TvarsQ[nsq]=Tvar[k];
                   8617:       TvarsQind[nsq]=k;
                   8618:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8619:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8620:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   8621:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  8622:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   8623:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   8624:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  8625:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  8626:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  8627:       ncova++;
                   8628:       TvarA[ncova]=Tvar[k];
                   8629:       TvarAind[ncova]=k;
1.231     brouard  8630:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  8631:        Fixed[k]= 2;
                   8632:        Dummy[k]= 2;
                   8633:        modell[k].maintype= ATYPE;
                   8634:        modell[k].subtype= APFD;
                   8635:        /* ncoveff++; */
1.227     brouard  8636:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  8637:        Fixed[k]= 2;
                   8638:        Dummy[k]= 3;
                   8639:        modell[k].maintype= ATYPE;
                   8640:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   8641:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  8642:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  8643:        Fixed[k]= 3;
                   8644:        Dummy[k]= 2;
                   8645:        modell[k].maintype= ATYPE;
                   8646:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   8647:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  8648:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  8649:        Fixed[k]= 3;
                   8650:        Dummy[k]= 3;
                   8651:        modell[k].maintype= ATYPE;
                   8652:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   8653:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  8654:       }
                   8655:     }else if (Typevar[k] == 2) {  /* product without age */
                   8656:       k1=Tposprod[k];
                   8657:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  8658:        if(Tvard[k1][2] <=ncovcol){
                   8659:          Fixed[k]= 1;
                   8660:          Dummy[k]= 0;
                   8661:          modell[k].maintype= FTYPE;
                   8662:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   8663:          ncovf++; /* Fixed variables without age */
                   8664:          TvarF[ncovf]=Tvar[k];
                   8665:          TvarFind[ncovf]=k;
                   8666:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8667:          Fixed[k]= 0;  /* or 2 ?*/
                   8668:          Dummy[k]= 1;
                   8669:          modell[k].maintype= FTYPE;
                   8670:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   8671:          ncovf++; /* Varying variables without age */
                   8672:          TvarF[ncovf]=Tvar[k];
                   8673:          TvarFind[ncovf]=k;
                   8674:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8675:          Fixed[k]= 1;
                   8676:          Dummy[k]= 0;
                   8677:          modell[k].maintype= VTYPE;
                   8678:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   8679:          ncovv++; /* Varying variables without age */
                   8680:          TvarV[ncovv]=Tvar[k];
                   8681:          TvarVind[ncovv]=k;
                   8682:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8683:          Fixed[k]= 1;
                   8684:          Dummy[k]= 1;
                   8685:          modell[k].maintype= VTYPE;
                   8686:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   8687:          ncovv++; /* Varying variables without age */
                   8688:          TvarV[ncovv]=Tvar[k];
                   8689:          TvarVind[ncovv]=k;
                   8690:        }
1.227     brouard  8691:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  8692:        if(Tvard[k1][2] <=ncovcol){
                   8693:          Fixed[k]= 0;  /* or 2 ?*/
                   8694:          Dummy[k]= 1;
                   8695:          modell[k].maintype= FTYPE;
                   8696:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   8697:          ncovf++; /* Fixed variables without age */
                   8698:          TvarF[ncovf]=Tvar[k];
                   8699:          TvarFind[ncovf]=k;
                   8700:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8701:          Fixed[k]= 1;
                   8702:          Dummy[k]= 1;
                   8703:          modell[k].maintype= VTYPE;
                   8704:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   8705:          ncovv++; /* Varying variables without age */
                   8706:          TvarV[ncovv]=Tvar[k];
                   8707:          TvarVind[ncovv]=k;
                   8708:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8709:          Fixed[k]= 1;
                   8710:          Dummy[k]= 1;
                   8711:          modell[k].maintype= VTYPE;
                   8712:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   8713:          ncovv++; /* Varying variables without age */
                   8714:          TvarV[ncovv]=Tvar[k];
                   8715:          TvarVind[ncovv]=k;
                   8716:          ncovv++; /* Varying variables without age */
                   8717:          TvarV[ncovv]=Tvar[k];
                   8718:          TvarVind[ncovv]=k;
                   8719:        }
1.227     brouard  8720:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  8721:        if(Tvard[k1][2] <=ncovcol){
                   8722:          Fixed[k]= 1;
                   8723:          Dummy[k]= 1;
                   8724:          modell[k].maintype= VTYPE;
                   8725:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   8726:          ncovv++; /* Varying variables without age */
                   8727:          TvarV[ncovv]=Tvar[k];
                   8728:          TvarVind[ncovv]=k;
                   8729:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8730:          Fixed[k]= 1;
                   8731:          Dummy[k]= 1;
                   8732:          modell[k].maintype= VTYPE;
                   8733:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   8734:          ncovv++; /* Varying variables without age */
                   8735:          TvarV[ncovv]=Tvar[k];
                   8736:          TvarVind[ncovv]=k;
                   8737:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8738:          Fixed[k]= 1;
                   8739:          Dummy[k]= 0;
                   8740:          modell[k].maintype= VTYPE;
                   8741:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   8742:          ncovv++; /* Varying variables without age */
                   8743:          TvarV[ncovv]=Tvar[k];
                   8744:          TvarVind[ncovv]=k;
                   8745:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8746:          Fixed[k]= 1;
                   8747:          Dummy[k]= 1;
                   8748:          modell[k].maintype= VTYPE;
                   8749:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   8750:          ncovv++; /* Varying variables without age */
                   8751:          TvarV[ncovv]=Tvar[k];
                   8752:          TvarVind[ncovv]=k;
                   8753:        }
1.227     brouard  8754:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  8755:        if(Tvard[k1][2] <=ncovcol){
                   8756:          Fixed[k]= 1;
                   8757:          Dummy[k]= 1;
                   8758:          modell[k].maintype= VTYPE;
                   8759:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   8760:          ncovv++; /* Varying variables without age */
                   8761:          TvarV[ncovv]=Tvar[k];
                   8762:          TvarVind[ncovv]=k;
                   8763:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8764:          Fixed[k]= 1;
                   8765:          Dummy[k]= 1;
                   8766:          modell[k].maintype= VTYPE;
                   8767:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   8768:          ncovv++; /* Varying variables without age */
                   8769:          TvarV[ncovv]=Tvar[k];
                   8770:          TvarVind[ncovv]=k;
                   8771:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8772:          Fixed[k]= 1;
                   8773:          Dummy[k]= 1;
                   8774:          modell[k].maintype= VTYPE;
                   8775:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   8776:          ncovv++; /* Varying variables without age */
                   8777:          TvarV[ncovv]=Tvar[k];
                   8778:          TvarVind[ncovv]=k;
                   8779:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8780:          Fixed[k]= 1;
                   8781:          Dummy[k]= 1;
                   8782:          modell[k].maintype= VTYPE;
                   8783:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   8784:          ncovv++; /* Varying variables without age */
                   8785:          TvarV[ncovv]=Tvar[k];
                   8786:          TvarVind[ncovv]=k;
                   8787:        }
1.227     brouard  8788:       }else{
1.240     brouard  8789:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   8790:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   8791:       } /*end k1*/
1.225     brouard  8792:     }else{
1.226     brouard  8793:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   8794:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  8795:     }
1.227     brouard  8796:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  8797:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  8798:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   8799:   }
                   8800:   /* Searching for doublons in the model */
                   8801:   for(k1=1; k1<= cptcovt;k1++){
                   8802:     for(k2=1; k2 <k1;k2++){
                   8803:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  8804:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   8805:          if(Tvar[k1]==Tvar[k2]){
                   8806:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   8807:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   8808:            return(1);
                   8809:          }
                   8810:        }else if (Typevar[k1] ==2){
                   8811:          k3=Tposprod[k1];
                   8812:          k4=Tposprod[k2];
                   8813:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   8814:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   8815:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   8816:            return(1);
                   8817:          }
                   8818:        }
1.227     brouard  8819:       }
                   8820:     }
1.225     brouard  8821:   }
                   8822:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   8823:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  8824:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   8825:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  8826:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  8827:   /*endread:*/
1.225     brouard  8828:   printf("Exiting decodemodel: ");
                   8829:   return (1);
1.136     brouard  8830: }
                   8831: 
1.169     brouard  8832: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.136     brouard  8833: {
                   8834:   int i, m;
1.218     brouard  8835:   int firstone=0;
                   8836:   
1.136     brouard  8837:   for (i=1; i<=imx; i++) {
                   8838:     for(m=2; (m<= maxwav); m++) {
                   8839:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   8840:        anint[m][i]=9999;
1.216     brouard  8841:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   8842:          s[m][i]=-1;
1.136     brouard  8843:       }
                   8844:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.169     brouard  8845:        *nberr = *nberr + 1;
1.218     brouard  8846:        if(firstone == 0){
                   8847:          firstone=1;
                   8848:        printf("Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\nOther similar cases in log file\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
                   8849:        }
                   8850:        fprintf(ficlog,"Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
1.136     brouard  8851:        s[m][i]=-1;
                   8852:       }
                   8853:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  8854:        (*nberr)++;
1.136     brouard  8855:        printf("Error! Month of death of individual %ld on line %d was unknown %2d, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,(int)moisdc[i]); 
                   8856:        fprintf(ficlog,"Error! Month of death of individual %ld on line %d was unknown %f, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,moisdc[i]); 
                   8857:        s[m][i]=-1; /* We prefer to skip it (and to skip it in version 0.8a1 too */
                   8858:       }
                   8859:     }
                   8860:   }
                   8861: 
                   8862:   for (i=1; i<=imx; i++)  {
                   8863:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   8864:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  8865:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  8866:        if (s[m][i] >= nlstate+1) {
1.169     brouard  8867:          if(agedc[i]>0){
                   8868:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  8869:              agev[m][i]=agedc[i];
1.214     brouard  8870:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  8871:            }else {
1.136     brouard  8872:              if ((int)andc[i]!=9999){
                   8873:                nbwarn++;
                   8874:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   8875:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   8876:                agev[m][i]=-1;
                   8877:              }
                   8878:            }
1.169     brouard  8879:          } /* agedc > 0 */
1.214     brouard  8880:        } /* end if */
1.136     brouard  8881:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   8882:                                 years but with the precision of a month */
                   8883:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   8884:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   8885:            agev[m][i]=1;
                   8886:          else if(agev[m][i] < *agemin){ 
                   8887:            *agemin=agev[m][i];
                   8888:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   8889:          }
                   8890:          else if(agev[m][i] >*agemax){
                   8891:            *agemax=agev[m][i];
1.156     brouard  8892:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  8893:          }
                   8894:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   8895:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  8896:        } /* en if 9*/
1.136     brouard  8897:        else { /* =9 */
1.214     brouard  8898:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  8899:          agev[m][i]=1;
                   8900:          s[m][i]=-1;
                   8901:        }
                   8902:       }
1.214     brouard  8903:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  8904:        agev[m][i]=1;
1.214     brouard  8905:       else{
                   8906:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   8907:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   8908:        agev[m][i]=0;
                   8909:       }
                   8910:     } /* End for lastpass */
                   8911:   }
1.136     brouard  8912:     
                   8913:   for (i=1; i<=imx; i++)  {
                   8914:     for(m=firstpass; (m<=lastpass); m++){
                   8915:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  8916:        (*nberr)++;
1.136     brouard  8917:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   8918:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   8919:        return 1;
                   8920:       }
                   8921:     }
                   8922:   }
                   8923: 
                   8924:   /*for (i=1; i<=imx; i++){
                   8925:   for (m=firstpass; (m<lastpass); m++){
                   8926:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   8927: }
                   8928: 
                   8929: }*/
                   8930: 
                   8931: 
1.139     brouard  8932:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   8933:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  8934: 
                   8935:   return (0);
1.164     brouard  8936:  /* endread:*/
1.136     brouard  8937:     printf("Exiting calandcheckages: ");
                   8938:     return (1);
                   8939: }
                   8940: 
1.172     brouard  8941: #if defined(_MSC_VER)
                   8942: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   8943: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   8944: //#include "stdafx.h"
                   8945: //#include <stdio.h>
                   8946: //#include <tchar.h>
                   8947: //#include <windows.h>
                   8948: //#include <iostream>
                   8949: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   8950: 
                   8951: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   8952: 
                   8953: BOOL IsWow64()
                   8954: {
                   8955:        BOOL bIsWow64 = FALSE;
                   8956: 
                   8957:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   8958:        //  (HANDLE, PBOOL);
                   8959: 
                   8960:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   8961: 
                   8962:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   8963:        const char funcName[] = "IsWow64Process";
                   8964:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   8965:                GetProcAddress(module, funcName);
                   8966: 
                   8967:        if (NULL != fnIsWow64Process)
                   8968:        {
                   8969:                if (!fnIsWow64Process(GetCurrentProcess(),
                   8970:                        &bIsWow64))
                   8971:                        //throw std::exception("Unknown error");
                   8972:                        printf("Unknown error\n");
                   8973:        }
                   8974:        return bIsWow64 != FALSE;
                   8975: }
                   8976: #endif
1.177     brouard  8977: 
1.191     brouard  8978: void syscompilerinfo(int logged)
1.167     brouard  8979:  {
                   8980:    /* #include "syscompilerinfo.h"*/
1.185     brouard  8981:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   8982:    /* /GS /W3 /Gy
                   8983:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   8984:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   8985:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  8986:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   8987:    */ 
                   8988:    /* 64 bits */
1.185     brouard  8989:    /*
                   8990:      /GS /W3 /Gy
                   8991:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   8992:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   8993:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   8994:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   8995:    /* Optimization are useless and O3 is slower than O2 */
                   8996:    /*
                   8997:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   8998:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   8999:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   9000:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   9001:    */
1.186     brouard  9002:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  9003:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   9004:       /PDB:"visual studio
                   9005:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   9006:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   9007:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   9008:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   9009:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   9010:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   9011:       uiAccess='false'"
                   9012:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   9013:       /NOLOGO /TLBID:1
                   9014:    */
1.177     brouard  9015: #if defined __INTEL_COMPILER
1.178     brouard  9016: #if defined(__GNUC__)
                   9017:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   9018: #endif
1.177     brouard  9019: #elif defined(__GNUC__) 
1.179     brouard  9020: #ifndef  __APPLE__
1.174     brouard  9021: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  9022: #endif
1.177     brouard  9023:    struct utsname sysInfo;
1.178     brouard  9024:    int cross = CROSS;
                   9025:    if (cross){
                   9026:           printf("Cross-");
1.191     brouard  9027:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  9028:    }
1.174     brouard  9029: #endif
                   9030: 
1.171     brouard  9031: #include <stdint.h>
1.178     brouard  9032: 
1.191     brouard  9033:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  9034: #if defined(__clang__)
1.191     brouard  9035:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  9036: #endif
                   9037: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  9038:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  9039: #endif
                   9040: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  9041:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  9042: #endif
                   9043: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  9044:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  9045: #endif
                   9046: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  9047:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  9048: #endif
                   9049: #if defined(_MSC_VER)
1.191     brouard  9050:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  9051: #endif
                   9052: #if defined(__PGI)
1.191     brouard  9053:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  9054: #endif
                   9055: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  9056:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  9057: #endif
1.191     brouard  9058:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  9059:    
1.167     brouard  9060: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   9061: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   9062:     // Windows (x64 and x86)
1.191     brouard  9063:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  9064: #elif __unix__ // all unices, not all compilers
                   9065:     // Unix
1.191     brouard  9066:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  9067: #elif __linux__
                   9068:     // linux
1.191     brouard  9069:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  9070: #elif __APPLE__
1.174     brouard  9071:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  9072:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  9073: #endif
                   9074: 
                   9075: /*  __MINGW32__          */
                   9076: /*  __CYGWIN__  */
                   9077: /* __MINGW64__  */
                   9078: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   9079: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   9080: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   9081: /* _WIN64  // Defined for applications for Win64. */
                   9082: /* _M_X64 // Defined for compilations that target x64 processors. */
                   9083: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  9084: 
1.167     brouard  9085: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  9086:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  9087: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  9088:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  9089: #else
1.191     brouard  9090:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  9091: #endif
                   9092: 
1.169     brouard  9093: #if defined(__GNUC__)
                   9094: # if defined(__GNUC_PATCHLEVEL__)
                   9095: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9096:                             + __GNUC_MINOR__ * 100 \
                   9097:                             + __GNUC_PATCHLEVEL__)
                   9098: # else
                   9099: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9100:                             + __GNUC_MINOR__ * 100)
                   9101: # endif
1.174     brouard  9102:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  9103:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  9104: 
                   9105:    if (uname(&sysInfo) != -1) {
                   9106:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  9107:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  9108:    }
                   9109:    else
                   9110:       perror("uname() error");
1.179     brouard  9111:    //#ifndef __INTEL_COMPILER 
                   9112: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  9113:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  9114:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  9115: #endif
1.169     brouard  9116: #endif
1.172     brouard  9117: 
                   9118:    //   void main()
                   9119:    //   {
1.169     brouard  9120: #if defined(_MSC_VER)
1.174     brouard  9121:    if (IsWow64()){
1.191     brouard  9122:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   9123:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  9124:    }
                   9125:    else{
1.191     brouard  9126:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   9127:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  9128:    }
1.172     brouard  9129:    //     printf("\nPress Enter to continue...");
                   9130:    //     getchar();
                   9131:    //   }
                   9132: 
1.169     brouard  9133: #endif
                   9134:    
1.167     brouard  9135: 
1.219     brouard  9136: }
1.136     brouard  9137: 
1.219     brouard  9138: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  9139:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  9140:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  9141:   /* double ftolpl = 1.e-10; */
1.180     brouard  9142:   double age, agebase, agelim;
1.203     brouard  9143:   double tot;
1.180     brouard  9144: 
1.202     brouard  9145:   strcpy(filerespl,"PL_");
                   9146:   strcat(filerespl,fileresu);
                   9147:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   9148:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9149:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9150:   }
1.227     brouard  9151:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   9152:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  9153:   pstamp(ficrespl);
1.203     brouard  9154:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  9155:   fprintf(ficrespl,"#Age ");
                   9156:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   9157:   fprintf(ficrespl,"\n");
1.180     brouard  9158:   
1.219     brouard  9159:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  9160: 
1.219     brouard  9161:   agebase=ageminpar;
                   9162:   agelim=agemaxpar;
1.180     brouard  9163: 
1.227     brouard  9164:   /* i1=pow(2,ncoveff); */
1.234     brouard  9165:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  9166:   if (cptcovn < 1){i1=1;}
1.180     brouard  9167: 
1.238     brouard  9168:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   9169:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9170:       if(TKresult[nres]!= k)
                   9171:        continue;
1.235     brouard  9172: 
1.238     brouard  9173:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9174:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   9175:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   9176:       /* k=k+1; */
                   9177:       /* to clean */
                   9178:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9179:       fprintf(ficrespl,"#******");
                   9180:       printf("#******");
                   9181:       fprintf(ficlog,"#******");
                   9182:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9183:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   9184:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9185:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9186:       }
                   9187:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9188:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9189:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9190:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9191:       }
                   9192:       fprintf(ficrespl,"******\n");
                   9193:       printf("******\n");
                   9194:       fprintf(ficlog,"******\n");
                   9195:       if(invalidvarcomb[k]){
                   9196:        printf("\nCombination (%d) ignored because no case \n",k); 
                   9197:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   9198:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   9199:        continue;
                   9200:       }
1.219     brouard  9201: 
1.238     brouard  9202:       fprintf(ficrespl,"#Age ");
                   9203:       for(j=1;j<=cptcoveff;j++) {
                   9204:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9205:       }
                   9206:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   9207:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  9208:     
1.238     brouard  9209:       for (age=agebase; age<=agelim; age++){
                   9210:        /* for (age=agebase; age<=agebase; age++){ */
                   9211:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   9212:        fprintf(ficrespl,"%.0f ",age );
                   9213:        for(j=1;j<=cptcoveff;j++)
                   9214:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9215:        tot=0.;
                   9216:        for(i=1; i<=nlstate;i++){
                   9217:          tot +=  prlim[i][i];
                   9218:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   9219:        }
                   9220:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   9221:       } /* Age */
                   9222:       /* was end of cptcod */
                   9223:     } /* cptcov */
                   9224:   } /* nres */
1.219     brouard  9225:   return 0;
1.180     brouard  9226: }
                   9227: 
1.218     brouard  9228: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   9229:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   9230:        
                   9231:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   9232:    * at any age between ageminpar and agemaxpar
                   9233:         */
1.235     brouard  9234:   int i, j, k, i1, nres=0 ;
1.217     brouard  9235:   /* double ftolpl = 1.e-10; */
                   9236:   double age, agebase, agelim;
                   9237:   double tot;
1.218     brouard  9238:   /* double ***mobaverage; */
                   9239:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  9240: 
                   9241:   strcpy(fileresplb,"PLB_");
                   9242:   strcat(fileresplb,fileresu);
                   9243:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   9244:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9245:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9246:   }
                   9247:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9248:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9249:   pstamp(ficresplb);
                   9250:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   9251:   fprintf(ficresplb,"#Age ");
                   9252:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   9253:   fprintf(ficresplb,"\n");
                   9254:   
1.218     brouard  9255:   
                   9256:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   9257:   
                   9258:   agebase=ageminpar;
                   9259:   agelim=agemaxpar;
                   9260:   
                   9261:   
1.227     brouard  9262:   i1=pow(2,cptcoveff);
1.218     brouard  9263:   if (cptcovn < 1){i1=1;}
1.227     brouard  9264:   
1.238     brouard  9265:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9266:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
                   9267:       if(TKresult[nres]!= k)
                   9268:        continue;
                   9269:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9270:       fprintf(ficresplb,"#******");
                   9271:       printf("#******");
                   9272:       fprintf(ficlog,"#******");
                   9273:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9274:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9275:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9276:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9277:       }
                   9278:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9279:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9280:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9281:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9282:       }
                   9283:       fprintf(ficresplb,"******\n");
                   9284:       printf("******\n");
                   9285:       fprintf(ficlog,"******\n");
                   9286:       if(invalidvarcomb[k]){
                   9287:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   9288:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   9289:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   9290:        continue;
                   9291:       }
1.218     brouard  9292:     
1.238     brouard  9293:       fprintf(ficresplb,"#Age ");
                   9294:       for(j=1;j<=cptcoveff;j++) {
                   9295:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9296:       }
                   9297:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   9298:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  9299:     
                   9300:     
1.238     brouard  9301:       for (age=agebase; age<=agelim; age++){
                   9302:        /* for (age=agebase; age<=agebase; age++){ */
                   9303:        if(mobilavproj > 0){
                   9304:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   9305:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9306:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  9307:        }else if (mobilavproj == 0){
                   9308:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9309:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9310:          exit(1);
                   9311:        }else{
                   9312:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9313:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.238     brouard  9314:        }
                   9315:        fprintf(ficresplb,"%.0f ",age );
                   9316:        for(j=1;j<=cptcoveff;j++)
                   9317:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9318:        tot=0.;
                   9319:        for(i=1; i<=nlstate;i++){
                   9320:          tot +=  bprlim[i][i];
                   9321:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   9322:        }
                   9323:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   9324:       } /* Age */
                   9325:       /* was end of cptcod */
                   9326:     } /* end of any combination */
                   9327:   } /* end of nres */  
1.218     brouard  9328:   /* hBijx(p, bage, fage); */
                   9329:   /* fclose(ficrespijb); */
                   9330:   
                   9331:   return 0;
1.217     brouard  9332: }
1.218     brouard  9333:  
1.180     brouard  9334: int hPijx(double *p, int bage, int fage){
                   9335:     /*------------- h Pij x at various ages ------------*/
                   9336: 
                   9337:   int stepsize;
                   9338:   int agelim;
                   9339:   int hstepm;
                   9340:   int nhstepm;
1.235     brouard  9341:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  9342: 
                   9343:   double agedeb;
                   9344:   double ***p3mat;
                   9345: 
1.201     brouard  9346:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  9347:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   9348:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9349:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9350:     }
                   9351:     printf("Computing pij: result on file '%s' \n", filerespij);
                   9352:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   9353:   
                   9354:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9355:     /*if (stepm<=24) stepsize=2;*/
                   9356: 
                   9357:     agelim=AGESUP;
                   9358:     hstepm=stepsize*YEARM; /* Every year of age */
                   9359:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  9360:                
1.180     brouard  9361:     /* hstepm=1;   aff par mois*/
                   9362:     pstamp(ficrespij);
                   9363:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  9364:     i1= pow(2,cptcoveff);
1.218     brouard  9365:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9366:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9367:                /*      k=k+1;  */
1.235     brouard  9368:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9369:     for(k=1; k<=i1;k++){
                   9370:       if(TKresult[nres]!= k)
                   9371:        continue;
1.183     brouard  9372:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  9373:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  9374:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  9375:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9376:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9377:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9378:       }
1.183     brouard  9379:       fprintf(ficrespij,"******\n");
                   9380:       
                   9381:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   9382:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   9383:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   9384:        
                   9385:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  9386:        
1.183     brouard  9387:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9388:        oldm=oldms;savm=savms;
1.235     brouard  9389:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  9390:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   9391:        for(i=1; i<=nlstate;i++)
                   9392:          for(j=1; j<=nlstate+ndeath;j++)
                   9393:            fprintf(ficrespij," %1d-%1d",i,j);
                   9394:        fprintf(ficrespij,"\n");
                   9395:        for (h=0; h<=nhstepm; h++){
                   9396:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9397:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  9398:          for(i=1; i<=nlstate;i++)
                   9399:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  9400:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  9401:          fprintf(ficrespij,"\n");
                   9402:        }
1.183     brouard  9403:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9404:        fprintf(ficrespij,"\n");
                   9405:       }
1.180     brouard  9406:       /*}*/
                   9407:     }
1.218     brouard  9408:     return 0;
1.180     brouard  9409: }
1.218     brouard  9410:  
                   9411:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  9412:     /*------------- h Bij x at various ages ------------*/
                   9413: 
                   9414:   int stepsize;
1.218     brouard  9415:   /* int agelim; */
                   9416:        int ageminl;
1.217     brouard  9417:   int hstepm;
                   9418:   int nhstepm;
1.238     brouard  9419:   int h, i, i1, j, k, nres;
1.218     brouard  9420:        
1.217     brouard  9421:   double agedeb;
                   9422:   double ***p3mat;
1.218     brouard  9423:        
                   9424:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   9425:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   9426:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9427:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9428:   }
                   9429:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   9430:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   9431:   
                   9432:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9433:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  9434:   
1.218     brouard  9435:   /* agelim=AGESUP; */
                   9436:   ageminl=30;
                   9437:   hstepm=stepsize*YEARM; /* Every year of age */
                   9438:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   9439:   
                   9440:   /* hstepm=1;   aff par mois*/
                   9441:   pstamp(ficrespijb);
                   9442:   fprintf(ficrespijb,"#****** h Pij x Back Probability to be in state i at age x-h being in j at x ");
1.227     brouard  9443:   i1= pow(2,cptcoveff);
1.218     brouard  9444:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9445:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9446:   /*   k=k+1;  */
1.238     brouard  9447:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9448:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
                   9449:       if(TKresult[nres]!= k)
                   9450:        continue;
                   9451:       fprintf(ficrespijb,"\n#****** ");
                   9452:       for(j=1;j<=cptcoveff;j++)
                   9453:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9454:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9455:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9456:       }
                   9457:       fprintf(ficrespijb,"******\n");
                   9458:       if(invalidvarcomb[k]){
                   9459:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   9460:        continue;
                   9461:       }
                   9462:       
                   9463:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   9464:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   9465:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   9466:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   9467:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   9468:        
                   9469:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   9470:        
                   9471:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9472:        /* oldm=oldms;savm=savms; */
                   9473:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9474:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k);
                   9475:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
                   9476:        fprintf(ficrespijb,"# Cov Agex agex-h hpijx with i,j=");
1.217     brouard  9477:        for(i=1; i<=nlstate;i++)
                   9478:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  9479:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  9480:        fprintf(ficrespijb,"\n");
1.238     brouard  9481:        for (h=0; h<=nhstepm; h++){
                   9482:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9483:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   9484:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   9485:          for(i=1; i<=nlstate;i++)
                   9486:            for(j=1; j<=nlstate+ndeath;j++)
                   9487:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   9488:          fprintf(ficrespijb,"\n");
                   9489:        }
                   9490:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9491:        fprintf(ficrespijb,"\n");
                   9492:       } /* end age deb */
                   9493:     } /* end combination */
                   9494:   } /* end nres */
1.218     brouard  9495:   return 0;
                   9496:  } /*  hBijx */
1.217     brouard  9497: 
1.180     brouard  9498: 
1.136     brouard  9499: /***********************************************/
                   9500: /**************** Main Program *****************/
                   9501: /***********************************************/
                   9502: 
                   9503: int main(int argc, char *argv[])
                   9504: {
                   9505: #ifdef GSL
                   9506:   const gsl_multimin_fminimizer_type *T;
                   9507:   size_t iteri = 0, it;
                   9508:   int rval = GSL_CONTINUE;
                   9509:   int status = GSL_SUCCESS;
                   9510:   double ssval;
                   9511: #endif
                   9512:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  9513:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  9514:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  9515:   int jj, ll, li, lj, lk;
1.136     brouard  9516:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  9517:   int num_filled;
1.136     brouard  9518:   int itimes;
                   9519:   int NDIM=2;
                   9520:   int vpopbased=0;
1.235     brouard  9521:   int nres=0;
1.136     brouard  9522: 
1.164     brouard  9523:   char ca[32], cb[32];
1.136     brouard  9524:   /*  FILE *fichtm; *//* Html File */
                   9525:   /* FILE *ficgp;*/ /*Gnuplot File */
                   9526:   struct stat info;
1.191     brouard  9527:   double agedeb=0.;
1.194     brouard  9528: 
                   9529:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  9530:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  9531: 
1.165     brouard  9532:   double fret;
1.191     brouard  9533:   double dum=0.; /* Dummy variable */
1.136     brouard  9534:   double ***p3mat;
1.218     brouard  9535:   /* double ***mobaverage; */
1.164     brouard  9536: 
                   9537:   char line[MAXLINE];
1.197     brouard  9538:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   9539: 
1.234     brouard  9540:   char  modeltemp[MAXLINE];
1.230     brouard  9541:   char resultline[MAXLINE];
                   9542:   
1.136     brouard  9543:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  9544:   char *tok, *val; /* pathtot */
1.136     brouard  9545:   int firstobs=1, lastobs=10;
1.195     brouard  9546:   int c,  h , cpt, c2;
1.191     brouard  9547:   int jl=0;
                   9548:   int i1, j1, jk, stepsize=0;
1.194     brouard  9549:   int count=0;
                   9550: 
1.164     brouard  9551:   int *tab; 
1.136     brouard  9552:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  9553:   int backcast=0;
1.136     brouard  9554:   int mobilav=0,popforecast=0;
1.191     brouard  9555:   int hstepm=0, nhstepm=0;
1.136     brouard  9556:   int agemortsup;
                   9557:   float  sumlpop=0.;
                   9558:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   9559:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   9560: 
1.191     brouard  9561:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  9562:   double ftolpl=FTOL;
                   9563:   double **prlim;
1.217     brouard  9564:   double **bprlim;
1.136     brouard  9565:   double ***param; /* Matrix of parameters */
                   9566:   double  *p;
                   9567:   double **matcov; /* Matrix of covariance */
1.203     brouard  9568:   double **hess; /* Hessian matrix */
1.136     brouard  9569:   double ***delti3; /* Scale */
                   9570:   double *delti; /* Scale */
                   9571:   double ***eij, ***vareij;
                   9572:   double **varpl; /* Variances of prevalence limits by age */
                   9573:   double *epj, vepp;
1.164     brouard  9574: 
1.136     brouard  9575:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  9576:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   9577: 
1.136     brouard  9578:   double **ximort;
1.145     brouard  9579:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  9580:   int *dcwave;
                   9581: 
1.164     brouard  9582:   char z[1]="c";
1.136     brouard  9583: 
                   9584:   /*char  *strt;*/
                   9585:   char strtend[80];
1.126     brouard  9586: 
1.164     brouard  9587: 
1.126     brouard  9588: /*   setlocale (LC_ALL, ""); */
                   9589: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   9590: /*   textdomain (PACKAGE); */
                   9591: /*   setlocale (LC_CTYPE, ""); */
                   9592: /*   setlocale (LC_MESSAGES, ""); */
                   9593: 
                   9594:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  9595:   rstart_time = time(NULL);  
                   9596:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   9597:   start_time = *localtime(&rstart_time);
1.126     brouard  9598:   curr_time=start_time;
1.157     brouard  9599:   /*tml = *localtime(&start_time.tm_sec);*/
                   9600:   /* strcpy(strstart,asctime(&tml)); */
                   9601:   strcpy(strstart,asctime(&start_time));
1.126     brouard  9602: 
                   9603: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  9604: /*  tp.tm_sec = tp.tm_sec +86400; */
                   9605: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  9606: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   9607: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   9608: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  9609: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  9610: /*   strt=asctime(&tmg); */
                   9611: /*   printf("Time(after) =%s",strstart);  */
                   9612: /*  (void) time (&time_value);
                   9613: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   9614: *  tm = *localtime(&time_value);
                   9615: *  strstart=asctime(&tm);
                   9616: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   9617: */
                   9618: 
                   9619:   nberr=0; /* Number of errors and warnings */
                   9620:   nbwarn=0;
1.184     brouard  9621: #ifdef WIN32
                   9622:   _getcwd(pathcd, size);
                   9623: #else
1.126     brouard  9624:   getcwd(pathcd, size);
1.184     brouard  9625: #endif
1.191     brouard  9626:   syscompilerinfo(0);
1.196     brouard  9627:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  9628:   if(argc <=1){
                   9629:     printf("\nEnter the parameter file name: ");
1.205     brouard  9630:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   9631:       printf("ERROR Empty parameter file name\n");
                   9632:       goto end;
                   9633:     }
1.126     brouard  9634:     i=strlen(pathr);
                   9635:     if(pathr[i-1]=='\n')
                   9636:       pathr[i-1]='\0';
1.156     brouard  9637:     i=strlen(pathr);
1.205     brouard  9638:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  9639:       pathr[i-1]='\0';
1.205     brouard  9640:     }
                   9641:     i=strlen(pathr);
                   9642:     if( i==0 ){
                   9643:       printf("ERROR Empty parameter file name\n");
                   9644:       goto end;
                   9645:     }
                   9646:     for (tok = pathr; tok != NULL; ){
1.126     brouard  9647:       printf("Pathr |%s|\n",pathr);
                   9648:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   9649:       printf("val= |%s| pathr=%s\n",val,pathr);
                   9650:       strcpy (pathtot, val);
                   9651:       if(pathr[0] == '\0') break; /* Dirty */
                   9652:     }
                   9653:   }
                   9654:   else{
                   9655:     strcpy(pathtot,argv[1]);
                   9656:   }
                   9657:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   9658:   /*cygwin_split_path(pathtot,path,optionfile);
                   9659:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   9660:   /* cutv(path,optionfile,pathtot,'\\');*/
                   9661: 
                   9662:   /* Split argv[0], imach program to get pathimach */
                   9663:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   9664:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9665:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9666:  /*   strcpy(pathimach,argv[0]); */
                   9667:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   9668:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   9669:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  9670: #ifdef WIN32
                   9671:   _chdir(path); /* Can be a relative path */
                   9672:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   9673: #else
1.126     brouard  9674:   chdir(path); /* Can be a relative path */
1.184     brouard  9675:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   9676: #endif
                   9677:   printf("Current directory %s!\n",pathcd);
1.126     brouard  9678:   strcpy(command,"mkdir ");
                   9679:   strcat(command,optionfilefiname);
                   9680:   if((outcmd=system(command)) != 0){
1.169     brouard  9681:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  9682:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   9683:     /* fclose(ficlog); */
                   9684: /*     exit(1); */
                   9685:   }
                   9686: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   9687: /*     perror("mkdir"); */
                   9688: /*   } */
                   9689: 
                   9690:   /*-------- arguments in the command line --------*/
                   9691: 
1.186     brouard  9692:   /* Main Log file */
1.126     brouard  9693:   strcat(filelog, optionfilefiname);
                   9694:   strcat(filelog,".log");    /* */
                   9695:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   9696:     printf("Problem with logfile %s\n",filelog);
                   9697:     goto end;
                   9698:   }
                   9699:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  9700:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  9701:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   9702:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   9703:  path=%s \n\
                   9704:  optionfile=%s\n\
                   9705:  optionfilext=%s\n\
1.156     brouard  9706:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  9707: 
1.197     brouard  9708:   syscompilerinfo(1);
1.167     brouard  9709: 
1.126     brouard  9710:   printf("Local time (at start):%s",strstart);
                   9711:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   9712:   fflush(ficlog);
                   9713: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  9714: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  9715: 
                   9716:   /* */
                   9717:   strcpy(fileres,"r");
                   9718:   strcat(fileres, optionfilefiname);
1.201     brouard  9719:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  9720:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  9721:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  9722: 
1.186     brouard  9723:   /* Main ---------arguments file --------*/
1.126     brouard  9724: 
                   9725:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  9726:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   9727:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  9728:     fflush(ficlog);
1.149     brouard  9729:     /* goto end; */
                   9730:     exit(70); 
1.126     brouard  9731:   }
                   9732: 
                   9733: 
                   9734: 
                   9735:   strcpy(filereso,"o");
1.201     brouard  9736:   strcat(filereso,fileresu);
1.126     brouard  9737:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   9738:     printf("Problem with Output resultfile: %s\n", filereso);
                   9739:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   9740:     fflush(ficlog);
                   9741:     goto end;
                   9742:   }
                   9743: 
                   9744:   /* Reads comments: lines beginning with '#' */
                   9745:   numlinepar=0;
1.197     brouard  9746: 
                   9747:     /* First parameter line */
                   9748:   while(fgets(line, MAXLINE, ficpar)) {
                   9749:     /* If line starts with a # it is a comment */
                   9750:     if (line[0] == '#') {
                   9751:       numlinepar++;
                   9752:       fputs(line,stdout);
                   9753:       fputs(line,ficparo);
                   9754:       fputs(line,ficlog);
                   9755:       continue;
                   9756:     }else
                   9757:       break;
                   9758:   }
                   9759:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   9760:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   9761:     if (num_filled != 5) {
                   9762:       printf("Should be 5 parameters\n");
                   9763:     }
1.126     brouard  9764:     numlinepar++;
1.197     brouard  9765:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   9766:   }
                   9767:   /* Second parameter line */
                   9768:   while(fgets(line, MAXLINE, ficpar)) {
                   9769:     /* If line starts with a # it is a comment */
                   9770:     if (line[0] == '#') {
                   9771:       numlinepar++;
                   9772:       fputs(line,stdout);
                   9773:       fputs(line,ficparo);
                   9774:       fputs(line,ficlog);
                   9775:       continue;
                   9776:     }else
                   9777:       break;
                   9778:   }
1.223     brouard  9779:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   9780:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   9781:     if (num_filled != 11) {
                   9782:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  9783:       printf("but line=%s\n",line);
1.197     brouard  9784:     }
1.223     brouard  9785:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  9786:   }
1.203     brouard  9787:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  9788:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  9789:   /* Third parameter line */
                   9790:   while(fgets(line, MAXLINE, ficpar)) {
                   9791:     /* If line starts with a # it is a comment */
                   9792:     if (line[0] == '#') {
                   9793:       numlinepar++;
                   9794:       fputs(line,stdout);
                   9795:       fputs(line,ficparo);
                   9796:       fputs(line,ficlog);
                   9797:       continue;
                   9798:     }else
                   9799:       break;
                   9800:   }
1.201     brouard  9801:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
                   9802:     if (num_filled == 0)
                   9803:             model[0]='\0';
                   9804:     else if (num_filled != 1){
1.197     brouard  9805:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   9806:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   9807:       model[0]='\0';
                   9808:       goto end;
                   9809:     }
                   9810:     else{
                   9811:       if (model[0]=='+'){
                   9812:        for(i=1; i<=strlen(model);i++)
                   9813:          modeltemp[i-1]=model[i];
1.201     brouard  9814:        strcpy(model,modeltemp); 
1.197     brouard  9815:       }
                   9816:     }
1.199     brouard  9817:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  9818:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  9819:   }
                   9820:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   9821:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   9822:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  9823:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   9824:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  9825:   fflush(ficlog);
1.190     brouard  9826:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   9827:   if(model[0]=='#'){
1.187     brouard  9828:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   9829:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   9830:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   9831:     if(mle != -1){
                   9832:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   9833:       exit(1);
                   9834:     }
                   9835:   }
1.126     brouard  9836:   while((c=getc(ficpar))=='#' && c!= EOF){
                   9837:     ungetc(c,ficpar);
                   9838:     fgets(line, MAXLINE, ficpar);
                   9839:     numlinepar++;
1.195     brouard  9840:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   9841:       z[0]=line[1];
                   9842:     }
                   9843:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  9844:     fputs(line, stdout);
                   9845:     //puts(line);
1.126     brouard  9846:     fputs(line,ficparo);
                   9847:     fputs(line,ficlog);
                   9848:   }
                   9849:   ungetc(c,ficpar);
                   9850: 
                   9851:    
1.145     brouard  9852:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.225     brouard  9853:   coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
1.233     brouard  9854:   cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.225     brouard  9855:   cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
1.136     brouard  9856:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   9857:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   9858:      v1+v2*age+v2*v3 makes cptcovn = 3
                   9859:   */
                   9860:   if (strlen(model)>1) 
1.187     brouard  9861:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  9862:   else
1.187     brouard  9863:     ncovmodel=2; /* Constant and age */
1.133     brouard  9864:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   9865:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  9866:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   9867:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   9868:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   9869:     fflush(stdout);
                   9870:     fclose (ficlog);
                   9871:     goto end;
                   9872:   }
1.126     brouard  9873:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   9874:   delti=delti3[1][1];
                   9875:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   9876:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
                   9877:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  9878:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   9879:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  9880:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   9881:     fclose (ficparo);
                   9882:     fclose (ficlog);
                   9883:     goto end;
                   9884:     exit(0);
1.220     brouard  9885:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  9886:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  9887:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   9888:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  9889:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   9890:     matcov=matrix(1,npar,1,npar);
1.203     brouard  9891:     hess=matrix(1,npar,1,npar);
1.220     brouard  9892:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  9893:     /* Read guessed parameters */
1.126     brouard  9894:     /* Reads comments: lines beginning with '#' */
                   9895:     while((c=getc(ficpar))=='#' && c!= EOF){
                   9896:       ungetc(c,ficpar);
                   9897:       fgets(line, MAXLINE, ficpar);
                   9898:       numlinepar++;
1.141     brouard  9899:       fputs(line,stdout);
1.126     brouard  9900:       fputs(line,ficparo);
                   9901:       fputs(line,ficlog);
                   9902:     }
                   9903:     ungetc(c,ficpar);
                   9904:     
                   9905:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   9906:     for(i=1; i <=nlstate; i++){
1.234     brouard  9907:       j=0;
1.126     brouard  9908:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  9909:        if(jj==i) continue;
                   9910:        j++;
                   9911:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   9912:        if ((i1 != i) || (j1 != jj)){
                   9913:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  9914: It might be a problem of design; if ncovcol and the model are correct\n \
                   9915: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  9916:          exit(1);
                   9917:        }
                   9918:        fprintf(ficparo,"%1d%1d",i1,j1);
                   9919:        if(mle==1)
                   9920:          printf("%1d%1d",i,jj);
                   9921:        fprintf(ficlog,"%1d%1d",i,jj);
                   9922:        for(k=1; k<=ncovmodel;k++){
                   9923:          fscanf(ficpar," %lf",&param[i][j][k]);
                   9924:          if(mle==1){
                   9925:            printf(" %lf",param[i][j][k]);
                   9926:            fprintf(ficlog," %lf",param[i][j][k]);
                   9927:          }
                   9928:          else
                   9929:            fprintf(ficlog," %lf",param[i][j][k]);
                   9930:          fprintf(ficparo," %lf",param[i][j][k]);
                   9931:        }
                   9932:        fscanf(ficpar,"\n");
                   9933:        numlinepar++;
                   9934:        if(mle==1)
                   9935:          printf("\n");
                   9936:        fprintf(ficlog,"\n");
                   9937:        fprintf(ficparo,"\n");
1.126     brouard  9938:       }
                   9939:     }  
                   9940:     fflush(ficlog);
1.234     brouard  9941:     
1.145     brouard  9942:     /* Reads scales values */
1.126     brouard  9943:     p=param[1][1];
                   9944:     
                   9945:     /* Reads comments: lines beginning with '#' */
                   9946:     while((c=getc(ficpar))=='#' && c!= EOF){
                   9947:       ungetc(c,ficpar);
                   9948:       fgets(line, MAXLINE, ficpar);
                   9949:       numlinepar++;
1.141     brouard  9950:       fputs(line,stdout);
1.126     brouard  9951:       fputs(line,ficparo);
                   9952:       fputs(line,ficlog);
                   9953:     }
                   9954:     ungetc(c,ficpar);
                   9955: 
                   9956:     for(i=1; i <=nlstate; i++){
                   9957:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  9958:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   9959:        if ( (i1-i) * (j1-j) != 0){
                   9960:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   9961:          exit(1);
                   9962:        }
                   9963:        printf("%1d%1d",i,j);
                   9964:        fprintf(ficparo,"%1d%1d",i1,j1);
                   9965:        fprintf(ficlog,"%1d%1d",i1,j1);
                   9966:        for(k=1; k<=ncovmodel;k++){
                   9967:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   9968:          printf(" %le",delti3[i][j][k]);
                   9969:          fprintf(ficparo," %le",delti3[i][j][k]);
                   9970:          fprintf(ficlog," %le",delti3[i][j][k]);
                   9971:        }
                   9972:        fscanf(ficpar,"\n");
                   9973:        numlinepar++;
                   9974:        printf("\n");
                   9975:        fprintf(ficparo,"\n");
                   9976:        fprintf(ficlog,"\n");
1.126     brouard  9977:       }
                   9978:     }
                   9979:     fflush(ficlog);
1.234     brouard  9980:     
1.145     brouard  9981:     /* Reads covariance matrix */
1.126     brouard  9982:     delti=delti3[1][1];
1.220     brouard  9983:                
                   9984:                
1.126     brouard  9985:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  9986:                
1.126     brouard  9987:     /* Reads comments: lines beginning with '#' */
                   9988:     while((c=getc(ficpar))=='#' && c!= EOF){
                   9989:       ungetc(c,ficpar);
                   9990:       fgets(line, MAXLINE, ficpar);
                   9991:       numlinepar++;
1.141     brouard  9992:       fputs(line,stdout);
1.126     brouard  9993:       fputs(line,ficparo);
                   9994:       fputs(line,ficlog);
                   9995:     }
                   9996:     ungetc(c,ficpar);
1.220     brouard  9997:                
1.126     brouard  9998:     matcov=matrix(1,npar,1,npar);
1.203     brouard  9999:     hess=matrix(1,npar,1,npar);
1.131     brouard  10000:     for(i=1; i <=npar; i++)
                   10001:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  10002:                
1.194     brouard  10003:     /* Scans npar lines */
1.126     brouard  10004:     for(i=1; i <=npar; i++){
1.226     brouard  10005:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  10006:       if(count != 3){
1.226     brouard  10007:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10008: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10009: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10010:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10011: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10012: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10013:        exit(1);
1.220     brouard  10014:       }else{
1.226     brouard  10015:        if(mle==1)
                   10016:          printf("%1d%1d%d",i1,j1,jk);
                   10017:       }
                   10018:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   10019:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  10020:       for(j=1; j <=i; j++){
1.226     brouard  10021:        fscanf(ficpar," %le",&matcov[i][j]);
                   10022:        if(mle==1){
                   10023:          printf(" %.5le",matcov[i][j]);
                   10024:        }
                   10025:        fprintf(ficlog," %.5le",matcov[i][j]);
                   10026:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  10027:       }
                   10028:       fscanf(ficpar,"\n");
                   10029:       numlinepar++;
                   10030:       if(mle==1)
1.220     brouard  10031:                                printf("\n");
1.126     brouard  10032:       fprintf(ficlog,"\n");
                   10033:       fprintf(ficparo,"\n");
                   10034:     }
1.194     brouard  10035:     /* End of read covariance matrix npar lines */
1.126     brouard  10036:     for(i=1; i <=npar; i++)
                   10037:       for(j=i+1;j<=npar;j++)
1.226     brouard  10038:        matcov[i][j]=matcov[j][i];
1.126     brouard  10039:     
                   10040:     if(mle==1)
                   10041:       printf("\n");
                   10042:     fprintf(ficlog,"\n");
                   10043:     
                   10044:     fflush(ficlog);
                   10045:     
                   10046:     /*-------- Rewriting parameter file ----------*/
                   10047:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   10048:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   10049:     strcat(rfileres,".");    /* */
                   10050:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10051:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  10052:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10053:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  10054:     }
                   10055:     fprintf(ficres,"#%s\n",version);
                   10056:   }    /* End of mle != -3 */
1.218     brouard  10057:   
1.186     brouard  10058:   /*  Main data
                   10059:    */
1.126     brouard  10060:   n= lastobs;
                   10061:   num=lvector(1,n);
                   10062:   moisnais=vector(1,n);
                   10063:   annais=vector(1,n);
                   10064:   moisdc=vector(1,n);
                   10065:   andc=vector(1,n);
1.220     brouard  10066:   weight=vector(1,n);
1.126     brouard  10067:   agedc=vector(1,n);
                   10068:   cod=ivector(1,n);
1.220     brouard  10069:   for(i=1;i<=n;i++){
1.234     brouard  10070:     num[i]=0;
                   10071:     moisnais[i]=0;
                   10072:     annais[i]=0;
                   10073:     moisdc[i]=0;
                   10074:     andc[i]=0;
                   10075:     agedc[i]=0;
                   10076:     cod[i]=0;
                   10077:     weight[i]=1.0; /* Equal weights, 1 by default */
                   10078:   }
1.126     brouard  10079:   mint=matrix(1,maxwav,1,n);
                   10080:   anint=matrix(1,maxwav,1,n);
1.131     brouard  10081:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  10082:   tab=ivector(1,NCOVMAX);
1.144     brouard  10083:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  10084:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  10085: 
1.136     brouard  10086:   /* Reads data from file datafile */
                   10087:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   10088:     goto end;
                   10089: 
                   10090:   /* Calculation of the number of parameters from char model */
1.234     brouard  10091:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  10092:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   10093:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   10094:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   10095:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  10096:   */
                   10097:   
                   10098:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   10099:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   10100:   TvarsD=ivector(1,NCOVMAX); /*  */
                   10101:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   10102:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  10103:   TvarF=ivector(1,NCOVMAX); /*  */
                   10104:   TvarFind=ivector(1,NCOVMAX); /*  */
                   10105:   TvarV=ivector(1,NCOVMAX); /*  */
                   10106:   TvarVind=ivector(1,NCOVMAX); /*  */
                   10107:   TvarA=ivector(1,NCOVMAX); /*  */
                   10108:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  10109:   TvarFD=ivector(1,NCOVMAX); /*  */
                   10110:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   10111:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   10112:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   10113:   TvarVD=ivector(1,NCOVMAX); /*  */
                   10114:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   10115:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   10116:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   10117: 
1.230     brouard  10118:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  10119:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  10120:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   10121:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   10122:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  10123:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   10124:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   10125:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   10126:   */
                   10127:   /* For model-covariate k tells which data-covariate to use but
                   10128:     because this model-covariate is a construction we invent a new column
                   10129:     ncovcol + k1
                   10130:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   10131:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  10132:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   10133:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  10134:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   10135:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  10136:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  10137:   */
1.145     brouard  10138:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   10139:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  10140:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   10141:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  10142:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  10143:                         4 covariates (3 plus signs)
                   10144:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   10145:                      */  
1.230     brouard  10146:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  10147:                                * individual dummy, fixed or varying:
                   10148:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   10149:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  10150:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   10151:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   10152:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   10153:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   10154:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  10155:                                * individual quantitative, fixed or varying:
                   10156:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   10157:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   10158:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  10159: /* Main decodemodel */
                   10160: 
1.187     brouard  10161: 
1.223     brouard  10162:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  10163:     goto end;
                   10164: 
1.137     brouard  10165:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   10166:     nbwarn++;
                   10167:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10168:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10169:   }
1.136     brouard  10170:     /*  if(mle==1){*/
1.137     brouard  10171:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   10172:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  10173:   }
                   10174: 
                   10175:     /*-calculation of age at interview from date of interview and age at death -*/
                   10176:   agev=matrix(1,maxwav,1,imx);
                   10177: 
                   10178:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   10179:     goto end;
                   10180: 
1.126     brouard  10181: 
1.136     brouard  10182:   agegomp=(int)agemin;
                   10183:   free_vector(moisnais,1,n);
                   10184:   free_vector(annais,1,n);
1.126     brouard  10185:   /* free_matrix(mint,1,maxwav,1,n);
                   10186:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  10187:   /* free_vector(moisdc,1,n); */
                   10188:   /* free_vector(andc,1,n); */
1.145     brouard  10189:   /* */
                   10190:   
1.126     brouard  10191:   wav=ivector(1,imx);
1.214     brouard  10192:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10193:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10194:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10195:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   10196:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   10197:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  10198:    
                   10199:   /* Concatenates waves */
1.214     brouard  10200:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   10201:      Death is a valid wave (if date is known).
                   10202:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   10203:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   10204:      and mw[mi+1][i]. dh depends on stepm.
                   10205:   */
                   10206: 
1.126     brouard  10207:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.145     brouard  10208:   /* */
                   10209:  
1.215     brouard  10210:   free_vector(moisdc,1,n);
                   10211:   free_vector(andc,1,n);
                   10212: 
1.126     brouard  10213:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   10214:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   10215:   ncodemax[1]=1;
1.145     brouard  10216:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  10217:   cptcoveff=0;
1.220     brouard  10218:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   10219:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  10220:   }
                   10221:   
                   10222:   ncovcombmax=pow(2,cptcoveff);
                   10223:   invalidvarcomb=ivector(1, ncovcombmax); 
                   10224:   for(i=1;i<ncovcombmax;i++)
                   10225:     invalidvarcomb[i]=0;
                   10226:   
1.211     brouard  10227:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  10228:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  10229:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  10230:   
1.200     brouard  10231:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  10232:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  10233:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  10234:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   10235:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   10236:    * (currently 0 or 1) in the data.
                   10237:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   10238:    * corresponding modality (h,j).
                   10239:    */
                   10240: 
1.145     brouard  10241:   h=0;
                   10242:   /*if (cptcovn > 0) */
1.126     brouard  10243:   m=pow(2,cptcoveff);
                   10244:  
1.144     brouard  10245:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  10246:           * For k=4 covariates, h goes from 1 to m=2**k
                   10247:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   10248:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  10249:           *     h\k   1     2     3     4
1.143     brouard  10250:           *______________________________  
                   10251:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   10252:           *     2     2     1     1     1
                   10253:           *     3 i=2 1     2     1     1
                   10254:           *     4     2     2     1     1
                   10255:           *     5 i=3 1 i=2 1     2     1
                   10256:           *     6     2     1     2     1
                   10257:           *     7 i=4 1     2     2     1
                   10258:           *     8     2     2     2     1
1.197     brouard  10259:           *     9 i=5 1 i=3 1 i=2 1     2
                   10260:           *    10     2     1     1     2
                   10261:           *    11 i=6 1     2     1     2
                   10262:           *    12     2     2     1     2
                   10263:           *    13 i=7 1 i=4 1     2     2    
                   10264:           *    14     2     1     2     2
                   10265:           *    15 i=8 1     2     2     2
                   10266:           *    16     2     2     2     2
1.143     brouard  10267:           */
1.212     brouard  10268:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  10269:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   10270:      * and the value of each covariate?
                   10271:      * V1=1, V2=1, V3=2, V4=1 ?
                   10272:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   10273:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   10274:      * In order to get the real value in the data, we use nbcode
                   10275:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   10276:      * We are keeping this crazy system in order to be able (in the future?) 
                   10277:      * to have more than 2 values (0 or 1) for a covariate.
                   10278:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   10279:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   10280:      *              bbbbbbbb
                   10281:      *              76543210     
                   10282:      *   h-1        00000101 (6-1=5)
1.219     brouard  10283:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  10284:      *           &
                   10285:      *     1        00000001 (1)
1.219     brouard  10286:      *              00000000        = 1 & ((h-1) >> (k-1))
                   10287:      *          +1= 00000001 =1 
1.211     brouard  10288:      *
                   10289:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   10290:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   10291:      *    >>k'            11
                   10292:      *          &   00000001
                   10293:      *            = 00000001
                   10294:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   10295:      * Reverse h=6 and m=16?
                   10296:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   10297:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   10298:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   10299:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   10300:      * V3=decodtabm(14,3,2**4)=2
                   10301:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   10302:      *(h-1) >> (j-1)    0011 =13 >> 2
                   10303:      *          &1 000000001
                   10304:      *           = 000000001
                   10305:      *         +1= 000000010 =2
                   10306:      *                  2211
                   10307:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   10308:      *                  V3=2
1.220     brouard  10309:                 * codtabm and decodtabm are identical
1.211     brouard  10310:      */
                   10311: 
1.145     brouard  10312: 
                   10313:  free_ivector(Ndum,-1,NCOVMAX);
                   10314: 
                   10315: 
1.126     brouard  10316:     
1.186     brouard  10317:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  10318:   strcpy(optionfilegnuplot,optionfilefiname);
                   10319:   if(mle==-3)
1.201     brouard  10320:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  10321:   strcat(optionfilegnuplot,".gp");
                   10322: 
                   10323:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   10324:     printf("Problem with file %s",optionfilegnuplot);
                   10325:   }
                   10326:   else{
1.204     brouard  10327:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  10328:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  10329:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   10330:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  10331:   }
                   10332:   /*  fclose(ficgp);*/
1.186     brouard  10333: 
                   10334: 
                   10335:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  10336: 
                   10337:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   10338:   if(mle==-3)
1.201     brouard  10339:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  10340:   strcat(optionfilehtm,".htm");
                   10341:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  10342:     printf("Problem with %s \n",optionfilehtm);
                   10343:     exit(0);
1.126     brouard  10344:   }
                   10345: 
                   10346:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   10347:   strcat(optionfilehtmcov,"-cov.htm");
                   10348:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   10349:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   10350:   }
                   10351:   else{
                   10352:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   10353: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10354: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  10355:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   10356:   }
                   10357: 
1.213     brouard  10358:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  10359: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   10360: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  10361: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10362: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  10363: \n\
                   10364: <hr  size=\"2\" color=\"#EC5E5E\">\
                   10365:  <ul><li><h4>Parameter files</h4>\n\
                   10366:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   10367:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   10368:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   10369:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   10370:  - Date and time at start: %s</ul>\n",\
                   10371:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   10372:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   10373:          fileres,fileres,\
                   10374:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   10375:   fflush(fichtm);
                   10376: 
                   10377:   strcpy(pathr,path);
                   10378:   strcat(pathr,optionfilefiname);
1.184     brouard  10379: #ifdef WIN32
                   10380:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   10381: #else
1.126     brouard  10382:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  10383: #endif
                   10384:          
1.126     brouard  10385:   
1.220     brouard  10386:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   10387:                 and for any valid combination of covariates
1.126     brouard  10388:      and prints on file fileres'p'. */
1.227     brouard  10389:   freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
                   10390:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  10391: 
                   10392:   fprintf(fichtm,"\n");
                   10393:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   10394: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   10395: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   10396:          imx,agemin,agemax,jmin,jmax,jmean);
                   10397:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.220     brouard  10398:        oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10399:        newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10400:        savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10401:        oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  10402: 
1.126     brouard  10403:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   10404:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   10405:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   10406: 
                   10407:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  10408:   /* For mortality only */
1.126     brouard  10409:   if (mle==-3){
1.136     brouard  10410:     ximort=matrix(1,NDIM,1,NDIM); 
1.220     brouard  10411:                for(i=1;i<=NDIM;i++)
                   10412:                        for(j=1;j<=NDIM;j++)
                   10413:                                ximort[i][j]=0.;
1.186     brouard  10414:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  10415:     cens=ivector(1,n);
                   10416:     ageexmed=vector(1,n);
                   10417:     agecens=vector(1,n);
                   10418:     dcwave=ivector(1,n);
1.223     brouard  10419:                
1.126     brouard  10420:     for (i=1; i<=imx; i++){
                   10421:       dcwave[i]=-1;
                   10422:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  10423:        if (s[m][i]>nlstate) {
                   10424:          dcwave[i]=m;
                   10425:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   10426:          break;
                   10427:        }
1.126     brouard  10428:     }
1.226     brouard  10429:     
1.126     brouard  10430:     for (i=1; i<=imx; i++) {
                   10431:       if (wav[i]>0){
1.226     brouard  10432:        ageexmed[i]=agev[mw[1][i]][i];
                   10433:        j=wav[i];
                   10434:        agecens[i]=1.; 
                   10435:        
                   10436:        if (ageexmed[i]> 1 && wav[i] > 0){
                   10437:          agecens[i]=agev[mw[j][i]][i];
                   10438:          cens[i]= 1;
                   10439:        }else if (ageexmed[i]< 1) 
                   10440:          cens[i]= -1;
                   10441:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   10442:          cens[i]=0 ;
1.126     brouard  10443:       }
                   10444:       else cens[i]=-1;
                   10445:     }
                   10446:     
                   10447:     for (i=1;i<=NDIM;i++) {
                   10448:       for (j=1;j<=NDIM;j++)
1.226     brouard  10449:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  10450:     }
                   10451:     
1.145     brouard  10452:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  10453:     /*printf("%lf %lf", p[1], p[2]);*/
                   10454:     
                   10455:     
1.136     brouard  10456: #ifdef GSL
                   10457:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  10458: #else
1.126     brouard  10459:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  10460: #endif
1.201     brouard  10461:     strcpy(filerespow,"POW-MORT_"); 
                   10462:     strcat(filerespow,fileresu);
1.126     brouard  10463:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   10464:       printf("Problem with resultfile: %s\n", filerespow);
                   10465:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   10466:     }
1.136     brouard  10467: #ifdef GSL
                   10468:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  10469: #else
1.126     brouard  10470:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  10471: #endif
1.126     brouard  10472:     /*  for (i=1;i<=nlstate;i++)
                   10473:        for(j=1;j<=nlstate+ndeath;j++)
                   10474:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   10475:     */
                   10476:     fprintf(ficrespow,"\n");
1.136     brouard  10477: #ifdef GSL
                   10478:     /* gsl starts here */ 
                   10479:     T = gsl_multimin_fminimizer_nmsimplex;
                   10480:     gsl_multimin_fminimizer *sfm = NULL;
                   10481:     gsl_vector *ss, *x;
                   10482:     gsl_multimin_function minex_func;
                   10483: 
                   10484:     /* Initial vertex size vector */
                   10485:     ss = gsl_vector_alloc (NDIM);
                   10486:     
                   10487:     if (ss == NULL){
                   10488:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   10489:     }
                   10490:     /* Set all step sizes to 1 */
                   10491:     gsl_vector_set_all (ss, 0.001);
                   10492: 
                   10493:     /* Starting point */
1.126     brouard  10494:     
1.136     brouard  10495:     x = gsl_vector_alloc (NDIM);
                   10496:     
                   10497:     if (x == NULL){
                   10498:       gsl_vector_free(ss);
                   10499:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   10500:     }
                   10501:   
                   10502:     /* Initialize method and iterate */
                   10503:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  10504:     /*     gsl_vector_set(x, 0, 0.0268); */
                   10505:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  10506:     gsl_vector_set(x, 0, p[1]);
                   10507:     gsl_vector_set(x, 1, p[2]);
                   10508: 
                   10509:     minex_func.f = &gompertz_f;
                   10510:     minex_func.n = NDIM;
                   10511:     minex_func.params = (void *)&p; /* ??? */
                   10512:     
                   10513:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   10514:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   10515:     
                   10516:     printf("Iterations beginning .....\n\n");
                   10517:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   10518: 
                   10519:     iteri=0;
                   10520:     while (rval == GSL_CONTINUE){
                   10521:       iteri++;
                   10522:       status = gsl_multimin_fminimizer_iterate(sfm);
                   10523:       
                   10524:       if (status) printf("error: %s\n", gsl_strerror (status));
                   10525:       fflush(0);
                   10526:       
                   10527:       if (status) 
                   10528:         break;
                   10529:       
                   10530:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   10531:       ssval = gsl_multimin_fminimizer_size (sfm);
                   10532:       
                   10533:       if (rval == GSL_SUCCESS)
                   10534:         printf ("converged to a local maximum at\n");
                   10535:       
                   10536:       printf("%5d ", iteri);
                   10537:       for (it = 0; it < NDIM; it++){
                   10538:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   10539:       }
                   10540:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   10541:     }
                   10542:     
                   10543:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   10544:     
                   10545:     gsl_vector_free(x); /* initial values */
                   10546:     gsl_vector_free(ss); /* inital step size */
                   10547:     for (it=0; it<NDIM; it++){
                   10548:       p[it+1]=gsl_vector_get(sfm->x,it);
                   10549:       fprintf(ficrespow," %.12lf", p[it]);
                   10550:     }
                   10551:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   10552: #endif
                   10553: #ifdef POWELL
                   10554:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   10555: #endif  
1.126     brouard  10556:     fclose(ficrespow);
                   10557:     
1.203     brouard  10558:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  10559: 
                   10560:     for(i=1; i <=NDIM; i++)
                   10561:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  10562:                                matcov[i][j]=matcov[j][i];
1.126     brouard  10563:     
                   10564:     printf("\nCovariance matrix\n ");
1.203     brouard  10565:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  10566:     for(i=1; i <=NDIM; i++) {
                   10567:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  10568:                                printf("%f ",matcov[i][j]);
                   10569:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  10570:       }
1.203     brouard  10571:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  10572:     }
                   10573:     
                   10574:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  10575:     for (i=1;i<=NDIM;i++) {
1.126     brouard  10576:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  10577:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   10578:     }
1.126     brouard  10579:     lsurv=vector(1,AGESUP);
                   10580:     lpop=vector(1,AGESUP);
                   10581:     tpop=vector(1,AGESUP);
                   10582:     lsurv[agegomp]=100000;
                   10583:     
                   10584:     for (k=agegomp;k<=AGESUP;k++) {
                   10585:       agemortsup=k;
                   10586:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   10587:     }
                   10588:     
                   10589:     for (k=agegomp;k<agemortsup;k++)
                   10590:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   10591:     
                   10592:     for (k=agegomp;k<agemortsup;k++){
                   10593:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   10594:       sumlpop=sumlpop+lpop[k];
                   10595:     }
                   10596:     
                   10597:     tpop[agegomp]=sumlpop;
                   10598:     for (k=agegomp;k<(agemortsup-3);k++){
                   10599:       /*  tpop[k+1]=2;*/
                   10600:       tpop[k+1]=tpop[k]-lpop[k];
                   10601:     }
                   10602:     
                   10603:     
                   10604:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   10605:     for (k=agegomp;k<(agemortsup-2);k++) 
                   10606:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   10607:     
                   10608:     
                   10609:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  10610:                ageminpar=50;
                   10611:                agemaxpar=100;
1.194     brouard  10612:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   10613:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10614: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10615: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   10616:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10617: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10618: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10619:     }else{
                   10620:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   10621:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  10622:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  10623:                }
1.201     brouard  10624:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  10625:                     stepm, weightopt,\
                   10626:                     model,imx,p,matcov,agemortsup);
                   10627:     
                   10628:     free_vector(lsurv,1,AGESUP);
                   10629:     free_vector(lpop,1,AGESUP);
                   10630:     free_vector(tpop,1,AGESUP);
1.220     brouard  10631:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  10632:     free_ivector(cens,1,n);
                   10633:     free_vector(agecens,1,n);
                   10634:     free_ivector(dcwave,1,n);
1.220     brouard  10635: #ifdef GSL
1.136     brouard  10636: #endif
1.186     brouard  10637:   } /* Endof if mle==-3 mortality only */
1.205     brouard  10638:   /* Standard  */
                   10639:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   10640:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10641:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  10642:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  10643:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10644:     for (k=1; k<=npar;k++)
                   10645:       printf(" %d %8.5f",k,p[k]);
                   10646:     printf("\n");
1.205     brouard  10647:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   10648:       /* mlikeli uses func not funcone */
                   10649:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   10650:     }
                   10651:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   10652:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10653:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   10654:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10655:     }
                   10656:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  10657:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10658:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10659:     for (k=1; k<=npar;k++)
                   10660:       printf(" %d %8.5f",k,p[k]);
                   10661:     printf("\n");
                   10662:     
                   10663:     /*--------- results files --------------*/
1.224     brouard  10664:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  10665:     
                   10666:     
                   10667:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10668:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10669:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10670:     for(i=1,jk=1; i <=nlstate; i++){
                   10671:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  10672:        if (k != i) {
                   10673:          printf("%d%d ",i,k);
                   10674:          fprintf(ficlog,"%d%d ",i,k);
                   10675:          fprintf(ficres,"%1d%1d ",i,k);
                   10676:          for(j=1; j <=ncovmodel; j++){
                   10677:            printf("%12.7f ",p[jk]);
                   10678:            fprintf(ficlog,"%12.7f ",p[jk]);
                   10679:            fprintf(ficres,"%12.7f ",p[jk]);
                   10680:            jk++; 
                   10681:          }
                   10682:          printf("\n");
                   10683:          fprintf(ficlog,"\n");
                   10684:          fprintf(ficres,"\n");
                   10685:        }
1.126     brouard  10686:       }
                   10687:     }
1.203     brouard  10688:     if(mle != 0){
                   10689:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  10690:       ftolhess=ftol; /* Usually correct */
1.203     brouard  10691:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   10692:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10693:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10694:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  10695:        for(k=1; k <=(nlstate+ndeath); k++){
                   10696:          if (k != i) {
                   10697:            printf("%d%d ",i,k);
                   10698:            fprintf(ficlog,"%d%d ",i,k);
                   10699:            for(j=1; j <=ncovmodel; j++){
                   10700:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10701:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10702:              jk++; 
                   10703:            }
                   10704:            printf("\n");
                   10705:            fprintf(ficlog,"\n");
                   10706:          }
                   10707:        }
1.193     brouard  10708:       }
1.203     brouard  10709:     } /* end of hesscov and Wald tests */
1.225     brouard  10710:     
1.203     brouard  10711:     /*  */
1.126     brouard  10712:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   10713:     printf("# Scales (for hessian or gradient estimation)\n");
                   10714:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   10715:     for(i=1,jk=1; i <=nlstate; i++){
                   10716:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  10717:        if (j!=i) {
                   10718:          fprintf(ficres,"%1d%1d",i,j);
                   10719:          printf("%1d%1d",i,j);
                   10720:          fprintf(ficlog,"%1d%1d",i,j);
                   10721:          for(k=1; k<=ncovmodel;k++){
                   10722:            printf(" %.5e",delti[jk]);
                   10723:            fprintf(ficlog," %.5e",delti[jk]);
                   10724:            fprintf(ficres," %.5e",delti[jk]);
                   10725:            jk++;
                   10726:          }
                   10727:          printf("\n");
                   10728:          fprintf(ficlog,"\n");
                   10729:          fprintf(ficres,"\n");
                   10730:        }
1.126     brouard  10731:       }
                   10732:     }
                   10733:     
                   10734:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  10735:     if(mle >= 1) /* To big for the screen */
1.126     brouard  10736:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   10737:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   10738:     /* # 121 Var(a12)\n\ */
                   10739:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   10740:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   10741:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   10742:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   10743:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   10744:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   10745:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   10746:     
                   10747:     
                   10748:     /* Just to have a covariance matrix which will be more understandable
                   10749:        even is we still don't want to manage dictionary of variables
                   10750:     */
                   10751:     for(itimes=1;itimes<=2;itimes++){
                   10752:       jj=0;
                   10753:       for(i=1; i <=nlstate; i++){
1.225     brouard  10754:        for(j=1; j <=nlstate+ndeath; j++){
                   10755:          if(j==i) continue;
                   10756:          for(k=1; k<=ncovmodel;k++){
                   10757:            jj++;
                   10758:            ca[0]= k+'a'-1;ca[1]='\0';
                   10759:            if(itimes==1){
                   10760:              if(mle>=1)
                   10761:                printf("#%1d%1d%d",i,j,k);
                   10762:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   10763:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   10764:            }else{
                   10765:              if(mle>=1)
                   10766:                printf("%1d%1d%d",i,j,k);
                   10767:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   10768:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   10769:            }
                   10770:            ll=0;
                   10771:            for(li=1;li <=nlstate; li++){
                   10772:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   10773:                if(lj==li) continue;
                   10774:                for(lk=1;lk<=ncovmodel;lk++){
                   10775:                  ll++;
                   10776:                  if(ll<=jj){
                   10777:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   10778:                    if(ll<jj){
                   10779:                      if(itimes==1){
                   10780:                        if(mle>=1)
                   10781:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10782:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10783:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10784:                      }else{
                   10785:                        if(mle>=1)
                   10786:                          printf(" %.5e",matcov[jj][ll]); 
                   10787:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   10788:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   10789:                      }
                   10790:                    }else{
                   10791:                      if(itimes==1){
                   10792:                        if(mle>=1)
                   10793:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   10794:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   10795:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   10796:                      }else{
                   10797:                        if(mle>=1)
                   10798:                          printf(" %.7e",matcov[jj][ll]); 
                   10799:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   10800:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   10801:                      }
                   10802:                    }
                   10803:                  }
                   10804:                } /* end lk */
                   10805:              } /* end lj */
                   10806:            } /* end li */
                   10807:            if(mle>=1)
                   10808:              printf("\n");
                   10809:            fprintf(ficlog,"\n");
                   10810:            fprintf(ficres,"\n");
                   10811:            numlinepar++;
                   10812:          } /* end k*/
                   10813:        } /*end j */
1.126     brouard  10814:       } /* end i */
                   10815:     } /* end itimes */
                   10816:     
                   10817:     fflush(ficlog);
                   10818:     fflush(ficres);
1.225     brouard  10819:     while(fgets(line, MAXLINE, ficpar)) {
                   10820:       /* If line starts with a # it is a comment */
                   10821:       if (line[0] == '#') {
                   10822:        numlinepar++;
                   10823:        fputs(line,stdout);
                   10824:        fputs(line,ficparo);
                   10825:        fputs(line,ficlog);
                   10826:        continue;
                   10827:       }else
                   10828:        break;
                   10829:     }
                   10830:     
1.209     brouard  10831:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   10832:     /*   ungetc(c,ficpar); */
                   10833:     /*   fgets(line, MAXLINE, ficpar); */
                   10834:     /*   fputs(line,stdout); */
                   10835:     /*   fputs(line,ficparo); */
                   10836:     /* } */
                   10837:     /* ungetc(c,ficpar); */
1.126     brouard  10838:     
                   10839:     estepm=0;
1.209     brouard  10840:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  10841:       
                   10842:       if (num_filled != 6) {
                   10843:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   10844:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   10845:        goto end;
                   10846:       }
                   10847:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   10848:     }
                   10849:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   10850:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   10851:     
1.209     brouard  10852:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  10853:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   10854:     if (fage <= 2) {
                   10855:       bage = ageminpar;
                   10856:       fage = agemaxpar;
                   10857:     }
                   10858:     
                   10859:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  10860:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   10861:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  10862:                
1.186     brouard  10863:     /* Other stuffs, more or less useful */    
1.126     brouard  10864:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10865:       ungetc(c,ficpar);
                   10866:       fgets(line, MAXLINE, ficpar);
1.141     brouard  10867:       fputs(line,stdout);
1.126     brouard  10868:       fputs(line,ficparo);
                   10869:     }
                   10870:     ungetc(c,ficpar);
                   10871:     
                   10872:     fscanf(ficpar,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav);
                   10873:     fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10874:     fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10875:     printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10876:     fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10877:     
                   10878:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10879:       ungetc(c,ficpar);
                   10880:       fgets(line, MAXLINE, ficpar);
1.141     brouard  10881:       fputs(line,stdout);
1.126     brouard  10882:       fputs(line,ficparo);
                   10883:     }
                   10884:     ungetc(c,ficpar);
                   10885:     
                   10886:     
                   10887:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   10888:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   10889:     
                   10890:     fscanf(ficpar,"pop_based=%d\n",&popbased);
1.193     brouard  10891:     fprintf(ficlog,"pop_based=%d\n",popbased);
1.126     brouard  10892:     fprintf(ficparo,"pop_based=%d\n",popbased);   
                   10893:     fprintf(ficres,"pop_based=%d\n",popbased);   
                   10894:     
                   10895:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10896:       ungetc(c,ficpar);
                   10897:       fgets(line, MAXLINE, ficpar);
1.141     brouard  10898:       fputs(line,stdout);
1.238     brouard  10899:       fputs(line,ficres);
1.126     brouard  10900:       fputs(line,ficparo);
                   10901:     }
                   10902:     ungetc(c,ficpar);
                   10903:     
                   10904:     fscanf(ficpar,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj);
                   10905:     fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10906:     printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10907:     fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10908:     fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10909:     /* day and month of proj2 are not used but only year anproj2.*/
                   10910:     
1.217     brouard  10911:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10912:       ungetc(c,ficpar);
                   10913:       fgets(line, MAXLINE, ficpar);
                   10914:       fputs(line,stdout);
                   10915:       fputs(line,ficparo);
1.238     brouard  10916:       fputs(line,ficres);
1.217     brouard  10917:     }
                   10918:     ungetc(c,ficpar);
                   10919:     
                   10920:     fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);
1.223     brouard  10921:     fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   10922:     fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   10923:     fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
1.217     brouard  10924:     /* day and month of proj2 are not used but only year anproj2.*/
1.126     brouard  10925:     
1.230     brouard  10926:     /* Results */
1.235     brouard  10927:     nresult=0;
1.230     brouard  10928:     while(fgets(line, MAXLINE, ficpar)) {
                   10929:       /* If line starts with a # it is a comment */
                   10930:       if (line[0] == '#') {
                   10931:        numlinepar++;
                   10932:        fputs(line,stdout);
                   10933:        fputs(line,ficparo);
                   10934:        fputs(line,ficlog);
1.238     brouard  10935:        fputs(line,ficres);
1.230     brouard  10936:        continue;
                   10937:       }else
                   10938:        break;
                   10939:     }
1.240     brouard  10940:     if (!feof(ficpar))
1.230     brouard  10941:     while((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
1.240     brouard  10942:       if (num_filled == 0){
1.230     brouard  10943:        resultline[0]='\0';
1.240     brouard  10944:       break;
                   10945:       } else if (num_filled != 1){
1.230     brouard  10946:        printf("ERROR %d: result line should be at minimum 'result=' %s\n",num_filled, line);
                   10947:       }
1.235     brouard  10948:       nresult++; /* Sum of resultlines */
                   10949:       printf("Result %d: result=%s\n",nresult, resultline);
                   10950:       if(nresult > MAXRESULTLINES){
                   10951:        printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   10952:        fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   10953:        goto end;
                   10954:       }
                   10955:       decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
1.238     brouard  10956:       fprintf(ficparo,"result: %s\n",resultline);
                   10957:       fprintf(ficres,"result: %s\n",resultline);
                   10958:       fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  10959:       while(fgets(line, MAXLINE, ficpar)) {
                   10960:        /* If line starts with a # it is a comment */
                   10961:        if (line[0] == '#') {
                   10962:          numlinepar++;
                   10963:          fputs(line,stdout);
                   10964:          fputs(line,ficparo);
1.238     brouard  10965:          fputs(line,ficres);
1.230     brouard  10966:          fputs(line,ficlog);
                   10967:          continue;
                   10968:        }else
                   10969:          break;
                   10970:       }
                   10971:       if (feof(ficpar))
                   10972:        break;
                   10973:       else{ /* Processess output results for this combination of covariate values */
                   10974:       }                                   
1.240     brouard  10975:     } /* end while */
1.230     brouard  10976: 
                   10977: 
1.126     brouard  10978:     
1.230     brouard  10979:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  10980:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  10981:     
                   10982:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  10983:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  10984:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  10985: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10986: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  10987:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  10988: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10989: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10990:     }else{
1.218     brouard  10991:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p);
1.220     brouard  10992:     }
                   10993:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.225     brouard  10994:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,prevfcast,backcast, estepm, \
                   10995:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  10996:                
1.225     brouard  10997:     /*------------ free_vector  -------------*/
                   10998:     /*  chdir(path); */
1.220     brouard  10999:                
1.215     brouard  11000:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   11001:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   11002:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   11003:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  11004:     free_lvector(num,1,n);
                   11005:     free_vector(agedc,1,n);
                   11006:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   11007:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   11008:     fclose(ficparo);
                   11009:     fclose(ficres);
1.220     brouard  11010:                
                   11011:                
1.186     brouard  11012:     /* Other results (useful)*/
1.220     brouard  11013:                
                   11014:                
1.126     brouard  11015:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  11016:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   11017:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  11018:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  11019:     fclose(ficrespl);
                   11020: 
                   11021:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  11022:     /*#include "hpijx.h"*/
                   11023:     hPijx(p, bage, fage);
1.145     brouard  11024:     fclose(ficrespij);
1.227     brouard  11025:     
1.220     brouard  11026:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  11027:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  11028:     k=1;
1.126     brouard  11029:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  11030:     
1.219     brouard  11031:     /* Prevalence for each covariates in probs[age][status][cov] */
1.218     brouard  11032:     probs= ma3x(1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.126     brouard  11033:     for(i=1;i<=AGESUP;i++)
1.219     brouard  11034:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  11035:        for(k=1;k<=ncovcombmax;k++)
                   11036:          probs[i][j][k]=0.;
1.219     brouard  11037:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
                   11038:     if (mobilav!=0 ||mobilavproj !=0 ) {
                   11039:       mobaverages= ma3x(1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.227     brouard  11040:       for(i=1;i<=AGESUP;i++)
                   11041:        for(j=1;j<=nlstate;j++)
                   11042:          for(k=1;k<=ncovcombmax;k++)
                   11043:            mobaverages[i][j][k]=0.;
1.219     brouard  11044:       mobaverage=mobaverages;
                   11045:       if (mobilav!=0) {
1.235     brouard  11046:        printf("Movingaveraging observed prevalence\n");
1.227     brouard  11047:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   11048:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   11049:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   11050:        }
1.219     brouard  11051:       }
                   11052:       /* /\* Prevalence for each covariates in probs[age][status][cov] *\/ */
                   11053:       /* prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   11054:       else if (mobilavproj !=0) {
1.235     brouard  11055:        printf("Movingaveraging projected observed prevalence\n");
1.227     brouard  11056:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   11057:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11058:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11059:        }
1.219     brouard  11060:       }
                   11061:     }/* end if moving average */
1.227     brouard  11062:     
1.126     brouard  11063:     /*---------- Forecasting ------------------*/
                   11064:     /*if((stepm == 1) && (strcmp(model,".")==0)){*/
                   11065:     if(prevfcast==1){
                   11066:       /*    if(stepm ==1){*/
1.225     brouard  11067:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  11068:     }
1.217     brouard  11069:     if(backcast==1){
1.219     brouard  11070:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11071:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11072:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   11073: 
                   11074:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   11075: 
                   11076:       bprlim=matrix(1,nlstate,1,nlstate);
                   11077:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   11078:       fclose(ficresplb);
                   11079: 
1.222     brouard  11080:       hBijx(p, bage, fage, mobaverage);
                   11081:       fclose(ficrespijb);
1.219     brouard  11082:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11083: 
                   11084:       /* prevbackforecast(fileresu, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, mobilavproj,
1.225     brouard  11085:         bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
1.219     brouard  11086:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11087:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11088:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11089:     }
1.217     brouard  11090:     
1.186     brouard  11091:  
                   11092:     /* ------ Other prevalence ratios------------ */
1.126     brouard  11093: 
1.215     brouard  11094:     free_ivector(wav,1,imx);
                   11095:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   11096:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   11097:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  11098:                
                   11099:                
1.127     brouard  11100:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  11101:                
1.201     brouard  11102:     strcpy(filerese,"E_");
                   11103:     strcat(filerese,fileresu);
1.126     brouard  11104:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   11105:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11106:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11107:     }
1.208     brouard  11108:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   11109:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  11110: 
                   11111:     pstamp(ficreseij);
1.219     brouard  11112:                
1.235     brouard  11113:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11114:     if (cptcovn < 1){i1=1;}
                   11115:     
                   11116:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11117:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
                   11118:       if(TKresult[nres]!= k)
                   11119:        continue;
1.219     brouard  11120:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  11121:       printf("\n#****** ");
1.225     brouard  11122:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11123:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11124:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11125:       }
                   11126:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11127:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11128:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  11129:       }
                   11130:       fprintf(ficreseij,"******\n");
1.235     brouard  11131:       printf("******\n");
1.219     brouard  11132:       
                   11133:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11134:       oldm=oldms;savm=savms;
1.235     brouard  11135:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  11136:       
1.219     brouard  11137:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  11138:     }
                   11139:     fclose(ficreseij);
1.208     brouard  11140:     printf("done evsij\n");fflush(stdout);
                   11141:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.218     brouard  11142:                
1.227     brouard  11143:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  11144:                
                   11145:                
1.201     brouard  11146:     strcpy(filerest,"T_");
                   11147:     strcat(filerest,fileresu);
1.127     brouard  11148:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   11149:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   11150:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   11151:     }
1.208     brouard  11152:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   11153:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.218     brouard  11154:                
1.126     brouard  11155: 
1.201     brouard  11156:     strcpy(fileresstde,"STDE_");
                   11157:     strcat(fileresstde,fileresu);
1.126     brouard  11158:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  11159:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   11160:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  11161:     }
1.227     brouard  11162:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   11163:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  11164: 
1.201     brouard  11165:     strcpy(filerescve,"CVE_");
                   11166:     strcat(filerescve,fileresu);
1.126     brouard  11167:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  11168:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   11169:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  11170:     }
1.227     brouard  11171:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   11172:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  11173: 
1.201     brouard  11174:     strcpy(fileresv,"V_");
                   11175:     strcat(fileresv,fileresu);
1.126     brouard  11176:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   11177:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11178:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11179:     }
1.227     brouard  11180:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   11181:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  11182: 
1.145     brouard  11183:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11184:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   11185:           
1.235     brouard  11186:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11187:     if (cptcovn < 1){i1=1;}
                   11188:     
                   11189:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11190:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
                   11191:       if(TKresult[nres]!= k)
                   11192:        continue;
1.242     brouard  11193:       printf("\n#****** Result for:");
                   11194:       fprintf(ficrest,"\n#****** Result for:");
                   11195:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  11196:       for(j=1;j<=cptcoveff;j++){ 
                   11197:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11198:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11199:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11200:       }
1.235     brouard  11201:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11202:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11203:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11204:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11205:       }        
1.208     brouard  11206:       fprintf(ficrest,"******\n");
1.227     brouard  11207:       fprintf(ficlog,"******\n");
                   11208:       printf("******\n");
1.208     brouard  11209:       
                   11210:       fprintf(ficresstdeij,"\n#****** ");
                   11211:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  11212:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11213:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11214:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  11215:       }
1.235     brouard  11216:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11217:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11218:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11219:       }        
1.208     brouard  11220:       fprintf(ficresstdeij,"******\n");
                   11221:       fprintf(ficrescveij,"******\n");
                   11222:       
                   11223:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  11224:       /* pstamp(ficresvij); */
1.225     brouard  11225:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  11226:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11227:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11228:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11229:       }        
1.208     brouard  11230:       fprintf(ficresvij,"******\n");
                   11231:       
                   11232:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11233:       oldm=oldms;savm=savms;
1.235     brouard  11234:       printf(" cvevsij ");
                   11235:       fprintf(ficlog, " cvevsij ");
                   11236:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  11237:       printf(" end cvevsij \n ");
                   11238:       fprintf(ficlog, " end cvevsij \n ");
                   11239:       
                   11240:       /*
                   11241:        */
                   11242:       /* goto endfree; */
                   11243:       
                   11244:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11245:       pstamp(ficrest);
                   11246:       
                   11247:       
                   11248:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  11249:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   11250:        cptcod= 0; /* To be deleted */
                   11251:        printf("varevsij vpopbased=%d \n",vpopbased);
                   11252:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  11253:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  11254:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   11255:        if(vpopbased==1)
                   11256:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   11257:        else
                   11258:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   11259:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   11260:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   11261:        fprintf(ficrest,"\n");
                   11262:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   11263:        epj=vector(1,nlstate+1);
                   11264:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   11265:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   11266:        for(age=bage; age <=fage ;age++){
1.235     brouard  11267:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  11268:          if (vpopbased==1) {
                   11269:            if(mobilav ==0){
                   11270:              for(i=1; i<=nlstate;i++)
                   11271:                prlim[i][i]=probs[(int)age][i][k];
                   11272:            }else{ /* mobilav */ 
                   11273:              for(i=1; i<=nlstate;i++)
                   11274:                prlim[i][i]=mobaverage[(int)age][i][k];
                   11275:            }
                   11276:          }
1.219     brouard  11277:          
1.227     brouard  11278:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   11279:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   11280:          /* printf(" age %4.0f ",age); */
                   11281:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   11282:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   11283:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   11284:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   11285:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   11286:            }
                   11287:            epj[nlstate+1] +=epj[j];
                   11288:          }
                   11289:          /* printf(" age %4.0f \n",age); */
1.219     brouard  11290:          
1.227     brouard  11291:          for(i=1, vepp=0.;i <=nlstate;i++)
                   11292:            for(j=1;j <=nlstate;j++)
                   11293:              vepp += vareij[i][j][(int)age];
                   11294:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   11295:          for(j=1;j <=nlstate;j++){
                   11296:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   11297:          }
                   11298:          fprintf(ficrest,"\n");
                   11299:        }
1.208     brouard  11300:       } /* End vpopbased */
                   11301:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11302:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11303:       free_vector(epj,1,nlstate+1);
1.235     brouard  11304:       printf("done selection\n");fflush(stdout);
                   11305:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  11306:       
1.145     brouard  11307:       /*}*/
1.235     brouard  11308:     } /* End k selection */
1.227     brouard  11309: 
                   11310:     printf("done State-specific expectancies\n");fflush(stdout);
                   11311:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   11312: 
1.126     brouard  11313:     /*------- Variance of period (stable) prevalence------*/   
1.227     brouard  11314:     
1.201     brouard  11315:     strcpy(fileresvpl,"VPL_");
                   11316:     strcat(fileresvpl,fileresu);
1.126     brouard  11317:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   11318:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   11319:       exit(0);
                   11320:     }
1.208     brouard  11321:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   11322:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.227     brouard  11323:     
1.145     brouard  11324:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11325:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
1.227     brouard  11326:     
1.235     brouard  11327:     i1=pow(2,cptcoveff);
                   11328:     if (cptcovn < 1){i1=1;}
                   11329: 
                   11330:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11331:     for(k=1; k<=i1;k++){
                   11332:       if(TKresult[nres]!= k)
                   11333:        continue;
1.227     brouard  11334:       fprintf(ficresvpl,"\n#****** ");
                   11335:       printf("\n#****** ");
                   11336:       fprintf(ficlog,"\n#****** ");
                   11337:       for(j=1;j<=cptcoveff;j++) {
                   11338:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11339:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11340:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11341:       }
1.235     brouard  11342:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11343:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11344:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11345:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11346:       }        
1.227     brouard  11347:       fprintf(ficresvpl,"******\n");
                   11348:       printf("******\n");
                   11349:       fprintf(ficlog,"******\n");
                   11350:       
                   11351:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   11352:       oldm=oldms;savm=savms;
1.235     brouard  11353:       varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, strstart, nres);
1.227     brouard  11354:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
1.145     brouard  11355:       /*}*/
1.126     brouard  11356:     }
1.227     brouard  11357:     
1.126     brouard  11358:     fclose(ficresvpl);
1.208     brouard  11359:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   11360:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
1.227     brouard  11361:     
                   11362:     free_vector(weight,1,n);
                   11363:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   11364:     free_imatrix(s,1,maxwav+1,1,n);
                   11365:     free_matrix(anint,1,maxwav,1,n); 
                   11366:     free_matrix(mint,1,maxwav,1,n);
                   11367:     free_ivector(cod,1,n);
                   11368:     free_ivector(tab,1,NCOVMAX);
                   11369:     fclose(ficresstdeij);
                   11370:     fclose(ficrescveij);
                   11371:     fclose(ficresvij);
                   11372:     fclose(ficrest);
                   11373:     fclose(ficpar);
                   11374:     
                   11375:     
1.126     brouard  11376:     /*---------- End : free ----------------*/
1.219     brouard  11377:     if (mobilav!=0 ||mobilavproj !=0)
                   11378:       free_ma3x(mobaverages,1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
1.218     brouard  11379:     free_ma3x(probs,1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  11380:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11381:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  11382:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  11383:   /* endfree:*/
                   11384:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11385:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11386:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11387:   free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
1.233     brouard  11388:   free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
1.227     brouard  11389:   free_matrix(coqvar,1,maxwav,1,n);
                   11390:   free_matrix(covar,0,NCOVMAX,1,n);
                   11391:   free_matrix(matcov,1,npar,1,npar);
                   11392:   free_matrix(hess,1,npar,1,npar);
                   11393:   /*free_vector(delti,1,npar);*/
                   11394:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11395:   free_matrix(agev,1,maxwav,1,imx);
                   11396:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   11397:   
                   11398:   free_ivector(ncodemax,1,NCOVMAX);
                   11399:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   11400:   free_ivector(Dummy,-1,NCOVMAX);
                   11401:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  11402:   free_ivector(DummyV,1,NCOVMAX);
                   11403:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  11404:   free_ivector(Typevar,-1,NCOVMAX);
                   11405:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  11406:   free_ivector(TvarsQ,1,NCOVMAX);
                   11407:   free_ivector(TvarsQind,1,NCOVMAX);
                   11408:   free_ivector(TvarsD,1,NCOVMAX);
                   11409:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  11410:   free_ivector(TvarFD,1,NCOVMAX);
                   11411:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  11412:   free_ivector(TvarF,1,NCOVMAX);
                   11413:   free_ivector(TvarFind,1,NCOVMAX);
                   11414:   free_ivector(TvarV,1,NCOVMAX);
                   11415:   free_ivector(TvarVind,1,NCOVMAX);
                   11416:   free_ivector(TvarA,1,NCOVMAX);
                   11417:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  11418:   free_ivector(TvarFQ,1,NCOVMAX);
                   11419:   free_ivector(TvarFQind,1,NCOVMAX);
                   11420:   free_ivector(TvarVD,1,NCOVMAX);
                   11421:   free_ivector(TvarVDind,1,NCOVMAX);
                   11422:   free_ivector(TvarVQ,1,NCOVMAX);
                   11423:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  11424:   free_ivector(Tvarsel,1,NCOVMAX);
                   11425:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  11426:   free_ivector(Tposprod,1,NCOVMAX);
                   11427:   free_ivector(Tprod,1,NCOVMAX);
                   11428:   free_ivector(Tvaraff,1,NCOVMAX);
                   11429:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   11430:   free_ivector(Tage,1,NCOVMAX);
                   11431:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  11432:   free_ivector(TmodelInvind,1,NCOVMAX);
                   11433:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  11434:   
                   11435:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   11436:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  11437:   fflush(fichtm);
                   11438:   fflush(ficgp);
                   11439:   
1.227     brouard  11440:   
1.126     brouard  11441:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  11442:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   11443:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  11444:   }else{
                   11445:     printf("End of Imach\n");
                   11446:     fprintf(ficlog,"End of Imach\n");
                   11447:   }
                   11448:   printf("See log file on %s\n",filelog);
                   11449:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  11450:   /*(void) gettimeofday(&end_time,&tzp);*/
                   11451:   rend_time = time(NULL);  
                   11452:   end_time = *localtime(&rend_time);
                   11453:   /* tml = *localtime(&end_time.tm_sec); */
                   11454:   strcpy(strtend,asctime(&end_time));
1.126     brouard  11455:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   11456:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  11457:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  11458:   
1.157     brouard  11459:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   11460:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   11461:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  11462:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   11463: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   11464:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11465:   fclose(fichtm);
                   11466:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11467:   fclose(fichtmcov);
                   11468:   fclose(ficgp);
                   11469:   fclose(ficlog);
                   11470:   /*------ End -----------*/
1.227     brouard  11471:   
                   11472:   
                   11473:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  11474: #ifdef WIN32
1.227     brouard  11475:   if (_chdir(pathcd) != 0)
                   11476:     printf("Can't move to directory %s!\n",path);
                   11477:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  11478: #else
1.227     brouard  11479:     if(chdir(pathcd) != 0)
                   11480:       printf("Can't move to directory %s!\n", path);
                   11481:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  11482: #endif 
1.126     brouard  11483:     printf("Current directory %s!\n",pathcd);
                   11484:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   11485:   sprintf(plotcmd,"gnuplot");
1.157     brouard  11486: #ifdef _WIN32
1.126     brouard  11487:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   11488: #endif
                   11489:   if(!stat(plotcmd,&info)){
1.158     brouard  11490:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11491:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  11492:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  11493:     }else
                   11494:       strcpy(pplotcmd,plotcmd);
1.157     brouard  11495: #ifdef __unix
1.126     brouard  11496:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   11497:     if(!stat(plotcmd,&info)){
1.158     brouard  11498:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11499:     }else
                   11500:       strcpy(pplotcmd,plotcmd);
                   11501: #endif
                   11502:   }else
                   11503:     strcpy(pplotcmd,plotcmd);
                   11504:   
                   11505:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  11506:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  11507:   
1.126     brouard  11508:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  11509:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  11510:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  11511:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  11512:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  11513:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  11514:   }
1.158     brouard  11515:   printf(" Successful, please wait...");
1.126     brouard  11516:   while (z[0] != 'q') {
                   11517:     /* chdir(path); */
1.154     brouard  11518:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  11519:     scanf("%s",z);
                   11520: /*     if (z[0] == 'c') system("./imach"); */
                   11521:     if (z[0] == 'e') {
1.158     brouard  11522: #ifdef __APPLE__
1.152     brouard  11523:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  11524: #elif __linux
                   11525:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  11526: #else
1.152     brouard  11527:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  11528: #endif
                   11529:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   11530:       system(pplotcmd);
1.126     brouard  11531:     }
                   11532:     else if (z[0] == 'g') system(plotcmd);
                   11533:     else if (z[0] == 'q') exit(0);
                   11534:   }
1.227     brouard  11535: end:
1.126     brouard  11536:   while (z[0] != 'q') {
1.195     brouard  11537:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  11538:     scanf("%s",z);
                   11539:   }
                   11540: }

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