Annotation of imach/src/imach.c, revision 1.251

1.251   ! brouard     1: /* $Id: imach.c,v 1.250 2016/09/08 16:07:27 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.251   ! brouard     4:   Revision 1.250  2016/09/08 16:07:27  brouard
        !             5:   Summary: continue
        !             6: 
1.250     brouard     7:   Revision 1.249  2016/09/07 17:14:18  brouard
                      8:   Summary: Starting values from frequencies
                      9: 
1.249     brouard    10:   Revision 1.248  2016/09/07 14:10:18  brouard
                     11:   *** empty log message ***
                     12: 
1.248     brouard    13:   Revision 1.247  2016/09/02 11:11:21  brouard
                     14:   *** empty log message ***
                     15: 
1.247     brouard    16:   Revision 1.246  2016/09/02 08:49:22  brouard
                     17:   *** empty log message ***
                     18: 
1.246     brouard    19:   Revision 1.245  2016/09/02 07:25:01  brouard
                     20:   *** empty log message ***
                     21: 
1.245     brouard    22:   Revision 1.244  2016/09/02 07:17:34  brouard
                     23:   *** empty log message ***
                     24: 
1.244     brouard    25:   Revision 1.243  2016/09/02 06:45:35  brouard
                     26:   *** empty log message ***
                     27: 
1.243     brouard    28:   Revision 1.242  2016/08/30 15:01:20  brouard
                     29:   Summary: Fixing a lots
                     30: 
1.242     brouard    31:   Revision 1.241  2016/08/29 17:17:25  brouard
                     32:   Summary: gnuplot problem in Back projection to fix
                     33: 
1.241     brouard    34:   Revision 1.240  2016/08/29 07:53:18  brouard
                     35:   Summary: Better
                     36: 
1.240     brouard    37:   Revision 1.239  2016/08/26 15:51:03  brouard
                     38:   Summary: Improvement in Powell output in order to copy and paste
                     39: 
                     40:   Author:
                     41: 
1.239     brouard    42:   Revision 1.238  2016/08/26 14:23:35  brouard
                     43:   Summary: Starting tests of 0.99
                     44: 
1.238     brouard    45:   Revision 1.237  2016/08/26 09:20:19  brouard
                     46:   Summary: to valgrind
                     47: 
1.237     brouard    48:   Revision 1.236  2016/08/25 10:50:18  brouard
                     49:   *** empty log message ***
                     50: 
1.236     brouard    51:   Revision 1.235  2016/08/25 06:59:23  brouard
                     52:   *** empty log message ***
                     53: 
1.235     brouard    54:   Revision 1.234  2016/08/23 16:51:20  brouard
                     55:   *** empty log message ***
                     56: 
1.234     brouard    57:   Revision 1.233  2016/08/23 07:40:50  brouard
                     58:   Summary: not working
                     59: 
1.233     brouard    60:   Revision 1.232  2016/08/22 14:20:21  brouard
                     61:   Summary: not working
                     62: 
1.232     brouard    63:   Revision 1.231  2016/08/22 07:17:15  brouard
                     64:   Summary: not working
                     65: 
1.231     brouard    66:   Revision 1.230  2016/08/22 06:55:53  brouard
                     67:   Summary: Not working
                     68: 
1.230     brouard    69:   Revision 1.229  2016/07/23 09:45:53  brouard
                     70:   Summary: Completing for func too
                     71: 
1.229     brouard    72:   Revision 1.228  2016/07/22 17:45:30  brouard
                     73:   Summary: Fixing some arrays, still debugging
                     74: 
1.227     brouard    75:   Revision 1.226  2016/07/12 18:42:34  brouard
                     76:   Summary: temp
                     77: 
1.226     brouard    78:   Revision 1.225  2016/07/12 08:40:03  brouard
                     79:   Summary: saving but not running
                     80: 
1.225     brouard    81:   Revision 1.224  2016/07/01 13:16:01  brouard
                     82:   Summary: Fixes
                     83: 
1.224     brouard    84:   Revision 1.223  2016/02/19 09:23:35  brouard
                     85:   Summary: temporary
                     86: 
1.223     brouard    87:   Revision 1.222  2016/02/17 08:14:50  brouard
                     88:   Summary: Probably last 0.98 stable version 0.98r6
                     89: 
1.222     brouard    90:   Revision 1.221  2016/02/15 23:35:36  brouard
                     91:   Summary: minor bug
                     92: 
1.220     brouard    93:   Revision 1.219  2016/02/15 00:48:12  brouard
                     94:   *** empty log message ***
                     95: 
1.219     brouard    96:   Revision 1.218  2016/02/12 11:29:23  brouard
                     97:   Summary: 0.99 Back projections
                     98: 
1.218     brouard    99:   Revision 1.217  2015/12/23 17:18:31  brouard
                    100:   Summary: Experimental backcast
                    101: 
1.217     brouard   102:   Revision 1.216  2015/12/18 17:32:11  brouard
                    103:   Summary: 0.98r4 Warning and status=-2
                    104: 
                    105:   Version 0.98r4 is now:
                    106:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    107:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    108:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    109: 
1.216     brouard   110:   Revision 1.215  2015/12/16 08:52:24  brouard
                    111:   Summary: 0.98r4 working
                    112: 
1.215     brouard   113:   Revision 1.214  2015/12/16 06:57:54  brouard
                    114:   Summary: temporary not working
                    115: 
1.214     brouard   116:   Revision 1.213  2015/12/11 18:22:17  brouard
                    117:   Summary: 0.98r4
                    118: 
1.213     brouard   119:   Revision 1.212  2015/11/21 12:47:24  brouard
                    120:   Summary: minor typo
                    121: 
1.212     brouard   122:   Revision 1.211  2015/11/21 12:41:11  brouard
                    123:   Summary: 0.98r3 with some graph of projected cross-sectional
                    124: 
                    125:   Author: Nicolas Brouard
                    126: 
1.211     brouard   127:   Revision 1.210  2015/11/18 17:41:20  brouard
                    128:   Summary: Start working on projected prevalences
                    129: 
1.210     brouard   130:   Revision 1.209  2015/11/17 22:12:03  brouard
                    131:   Summary: Adding ftolpl parameter
                    132:   Author: N Brouard
                    133: 
                    134:   We had difficulties to get smoothed confidence intervals. It was due
                    135:   to the period prevalence which wasn't computed accurately. The inner
                    136:   parameter ftolpl is now an outer parameter of the .imach parameter
                    137:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    138:   computation are long.
                    139: 
1.209     brouard   140:   Revision 1.208  2015/11/17 14:31:57  brouard
                    141:   Summary: temporary
                    142: 
1.208     brouard   143:   Revision 1.207  2015/10/27 17:36:57  brouard
                    144:   *** empty log message ***
                    145: 
1.207     brouard   146:   Revision 1.206  2015/10/24 07:14:11  brouard
                    147:   *** empty log message ***
                    148: 
1.206     brouard   149:   Revision 1.205  2015/10/23 15:50:53  brouard
                    150:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    151: 
1.205     brouard   152:   Revision 1.204  2015/10/01 16:20:26  brouard
                    153:   Summary: Some new graphs of contribution to likelihood
                    154: 
1.204     brouard   155:   Revision 1.203  2015/09/30 17:45:14  brouard
                    156:   Summary: looking at better estimation of the hessian
                    157: 
                    158:   Also a better criteria for convergence to the period prevalence And
                    159:   therefore adding the number of years needed to converge. (The
                    160:   prevalence in any alive state shold sum to one
                    161: 
1.203     brouard   162:   Revision 1.202  2015/09/22 19:45:16  brouard
                    163:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    164: 
1.202     brouard   165:   Revision 1.201  2015/09/15 17:34:58  brouard
                    166:   Summary: 0.98r0
                    167: 
                    168:   - Some new graphs like suvival functions
                    169:   - Some bugs fixed like model=1+age+V2.
                    170: 
1.201     brouard   171:   Revision 1.200  2015/09/09 16:53:55  brouard
                    172:   Summary: Big bug thanks to Flavia
                    173: 
                    174:   Even model=1+age+V2. did not work anymore
                    175: 
1.200     brouard   176:   Revision 1.199  2015/09/07 14:09:23  brouard
                    177:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    178: 
1.199     brouard   179:   Revision 1.198  2015/09/03 07:14:39  brouard
                    180:   Summary: 0.98q5 Flavia
                    181: 
1.198     brouard   182:   Revision 1.197  2015/09/01 18:24:39  brouard
                    183:   *** empty log message ***
                    184: 
1.197     brouard   185:   Revision 1.196  2015/08/18 23:17:52  brouard
                    186:   Summary: 0.98q5
                    187: 
1.196     brouard   188:   Revision 1.195  2015/08/18 16:28:39  brouard
                    189:   Summary: Adding a hack for testing purpose
                    190: 
                    191:   After reading the title, ftol and model lines, if the comment line has
                    192:   a q, starting with #q, the answer at the end of the run is quit. It
                    193:   permits to run test files in batch with ctest. The former workaround was
                    194:   $ echo q | imach foo.imach
                    195: 
1.195     brouard   196:   Revision 1.194  2015/08/18 13:32:00  brouard
                    197:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    198: 
1.194     brouard   199:   Revision 1.193  2015/08/04 07:17:42  brouard
                    200:   Summary: 0.98q4
                    201: 
1.193     brouard   202:   Revision 1.192  2015/07/16 16:49:02  brouard
                    203:   Summary: Fixing some outputs
                    204: 
1.192     brouard   205:   Revision 1.191  2015/07/14 10:00:33  brouard
                    206:   Summary: Some fixes
                    207: 
1.191     brouard   208:   Revision 1.190  2015/05/05 08:51:13  brouard
                    209:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    210: 
                    211:   Fix 1+age+.
                    212: 
1.190     brouard   213:   Revision 1.189  2015/04/30 14:45:16  brouard
                    214:   Summary: 0.98q2
                    215: 
1.189     brouard   216:   Revision 1.188  2015/04/30 08:27:53  brouard
                    217:   *** empty log message ***
                    218: 
1.188     brouard   219:   Revision 1.187  2015/04/29 09:11:15  brouard
                    220:   *** empty log message ***
                    221: 
1.187     brouard   222:   Revision 1.186  2015/04/23 12:01:52  brouard
                    223:   Summary: V1*age is working now, version 0.98q1
                    224: 
                    225:   Some codes had been disabled in order to simplify and Vn*age was
                    226:   working in the optimization phase, ie, giving correct MLE parameters,
                    227:   but, as usual, outputs were not correct and program core dumped.
                    228: 
1.186     brouard   229:   Revision 1.185  2015/03/11 13:26:42  brouard
                    230:   Summary: Inclusion of compile and links command line for Intel Compiler
                    231: 
1.185     brouard   232:   Revision 1.184  2015/03/11 11:52:39  brouard
                    233:   Summary: Back from Windows 8. Intel Compiler
                    234: 
1.184     brouard   235:   Revision 1.183  2015/03/10 20:34:32  brouard
                    236:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    237: 
                    238:   We use directest instead of original Powell test; probably no
                    239:   incidence on the results, but better justifications;
                    240:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    241:   wrong results.
                    242: 
1.183     brouard   243:   Revision 1.182  2015/02/12 08:19:57  brouard
                    244:   Summary: Trying to keep directest which seems simpler and more general
                    245:   Author: Nicolas Brouard
                    246: 
1.182     brouard   247:   Revision 1.181  2015/02/11 23:22:24  brouard
                    248:   Summary: Comments on Powell added
                    249: 
                    250:   Author:
                    251: 
1.181     brouard   252:   Revision 1.180  2015/02/11 17:33:45  brouard
                    253:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    254: 
1.180     brouard   255:   Revision 1.179  2015/01/04 09:57:06  brouard
                    256:   Summary: back to OS/X
                    257: 
1.179     brouard   258:   Revision 1.178  2015/01/04 09:35:48  brouard
                    259:   *** empty log message ***
                    260: 
1.178     brouard   261:   Revision 1.177  2015/01/03 18:40:56  brouard
                    262:   Summary: Still testing ilc32 on OSX
                    263: 
1.177     brouard   264:   Revision 1.176  2015/01/03 16:45:04  brouard
                    265:   *** empty log message ***
                    266: 
1.176     brouard   267:   Revision 1.175  2015/01/03 16:33:42  brouard
                    268:   *** empty log message ***
                    269: 
1.175     brouard   270:   Revision 1.174  2015/01/03 16:15:49  brouard
                    271:   Summary: Still in cross-compilation
                    272: 
1.174     brouard   273:   Revision 1.173  2015/01/03 12:06:26  brouard
                    274:   Summary: trying to detect cross-compilation
                    275: 
1.173     brouard   276:   Revision 1.172  2014/12/27 12:07:47  brouard
                    277:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    278: 
1.172     brouard   279:   Revision 1.171  2014/12/23 13:26:59  brouard
                    280:   Summary: Back from Visual C
                    281: 
                    282:   Still problem with utsname.h on Windows
                    283: 
1.171     brouard   284:   Revision 1.170  2014/12/23 11:17:12  brouard
                    285:   Summary: Cleaning some \%% back to %%
                    286: 
                    287:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    288: 
1.170     brouard   289:   Revision 1.169  2014/12/22 23:08:31  brouard
                    290:   Summary: 0.98p
                    291: 
                    292:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    293: 
1.169     brouard   294:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   295:   Summary: update
1.169     brouard   296: 
1.168     brouard   297:   Revision 1.167  2014/12/22 13:50:56  brouard
                    298:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    299: 
                    300:   Testing on Linux 64
                    301: 
1.167     brouard   302:   Revision 1.166  2014/12/22 11:40:47  brouard
                    303:   *** empty log message ***
                    304: 
1.166     brouard   305:   Revision 1.165  2014/12/16 11:20:36  brouard
                    306:   Summary: After compiling on Visual C
                    307: 
                    308:   * imach.c (Module): Merging 1.61 to 1.162
                    309: 
1.165     brouard   310:   Revision 1.164  2014/12/16 10:52:11  brouard
                    311:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    312: 
                    313:   * imach.c (Module): Merging 1.61 to 1.162
                    314: 
1.164     brouard   315:   Revision 1.163  2014/12/16 10:30:11  brouard
                    316:   * imach.c (Module): Merging 1.61 to 1.162
                    317: 
1.163     brouard   318:   Revision 1.162  2014/09/25 11:43:39  brouard
                    319:   Summary: temporary backup 0.99!
                    320: 
1.162     brouard   321:   Revision 1.1  2014/09/16 11:06:58  brouard
                    322:   Summary: With some code (wrong) for nlopt
                    323: 
                    324:   Author:
                    325: 
                    326:   Revision 1.161  2014/09/15 20:41:41  brouard
                    327:   Summary: Problem with macro SQR on Intel compiler
                    328: 
1.161     brouard   329:   Revision 1.160  2014/09/02 09:24:05  brouard
                    330:   *** empty log message ***
                    331: 
1.160     brouard   332:   Revision 1.159  2014/09/01 10:34:10  brouard
                    333:   Summary: WIN32
                    334:   Author: Brouard
                    335: 
1.159     brouard   336:   Revision 1.158  2014/08/27 17:11:51  brouard
                    337:   *** empty log message ***
                    338: 
1.158     brouard   339:   Revision 1.157  2014/08/27 16:26:55  brouard
                    340:   Summary: Preparing windows Visual studio version
                    341:   Author: Brouard
                    342: 
                    343:   In order to compile on Visual studio, time.h is now correct and time_t
                    344:   and tm struct should be used. difftime should be used but sometimes I
                    345:   just make the differences in raw time format (time(&now).
                    346:   Trying to suppress #ifdef LINUX
                    347:   Add xdg-open for __linux in order to open default browser.
                    348: 
1.157     brouard   349:   Revision 1.156  2014/08/25 20:10:10  brouard
                    350:   *** empty log message ***
                    351: 
1.156     brouard   352:   Revision 1.155  2014/08/25 18:32:34  brouard
                    353:   Summary: New compile, minor changes
                    354:   Author: Brouard
                    355: 
1.155     brouard   356:   Revision 1.154  2014/06/20 17:32:08  brouard
                    357:   Summary: Outputs now all graphs of convergence to period prevalence
                    358: 
1.154     brouard   359:   Revision 1.153  2014/06/20 16:45:46  brouard
                    360:   Summary: If 3 live state, convergence to period prevalence on same graph
                    361:   Author: Brouard
                    362: 
1.153     brouard   363:   Revision 1.152  2014/06/18 17:54:09  brouard
                    364:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    365: 
1.152     brouard   366:   Revision 1.151  2014/06/18 16:43:30  brouard
                    367:   *** empty log message ***
                    368: 
1.151     brouard   369:   Revision 1.150  2014/06/18 16:42:35  brouard
                    370:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    371:   Author: brouard
                    372: 
1.150     brouard   373:   Revision 1.149  2014/06/18 15:51:14  brouard
                    374:   Summary: Some fixes in parameter files errors
                    375:   Author: Nicolas Brouard
                    376: 
1.149     brouard   377:   Revision 1.148  2014/06/17 17:38:48  brouard
                    378:   Summary: Nothing new
                    379:   Author: Brouard
                    380: 
                    381:   Just a new packaging for OS/X version 0.98nS
                    382: 
1.148     brouard   383:   Revision 1.147  2014/06/16 10:33:11  brouard
                    384:   *** empty log message ***
                    385: 
1.147     brouard   386:   Revision 1.146  2014/06/16 10:20:28  brouard
                    387:   Summary: Merge
                    388:   Author: Brouard
                    389: 
                    390:   Merge, before building revised version.
                    391: 
1.146     brouard   392:   Revision 1.145  2014/06/10 21:23:15  brouard
                    393:   Summary: Debugging with valgrind
                    394:   Author: Nicolas Brouard
                    395: 
                    396:   Lot of changes in order to output the results with some covariates
                    397:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    398:   improve the code.
                    399:   No more memory valgrind error but a lot has to be done in order to
                    400:   continue the work of splitting the code into subroutines.
                    401:   Also, decodemodel has been improved. Tricode is still not
                    402:   optimal. nbcode should be improved. Documentation has been added in
                    403:   the source code.
                    404: 
1.144     brouard   405:   Revision 1.143  2014/01/26 09:45:38  brouard
                    406:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    407: 
                    408:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    409:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    410: 
1.143     brouard   411:   Revision 1.142  2014/01/26 03:57:36  brouard
                    412:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    413: 
                    414:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    415: 
1.142     brouard   416:   Revision 1.141  2014/01/26 02:42:01  brouard
                    417:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    418: 
1.141     brouard   419:   Revision 1.140  2011/09/02 10:37:54  brouard
                    420:   Summary: times.h is ok with mingw32 now.
                    421: 
1.140     brouard   422:   Revision 1.139  2010/06/14 07:50:17  brouard
                    423:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    424:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    425: 
1.139     brouard   426:   Revision 1.138  2010/04/30 18:19:40  brouard
                    427:   *** empty log message ***
                    428: 
1.138     brouard   429:   Revision 1.137  2010/04/29 18:11:38  brouard
                    430:   (Module): Checking covariates for more complex models
                    431:   than V1+V2. A lot of change to be done. Unstable.
                    432: 
1.137     brouard   433:   Revision 1.136  2010/04/26 20:30:53  brouard
                    434:   (Module): merging some libgsl code. Fixing computation
                    435:   of likelione (using inter/intrapolation if mle = 0) in order to
                    436:   get same likelihood as if mle=1.
                    437:   Some cleaning of code and comments added.
                    438: 
1.136     brouard   439:   Revision 1.135  2009/10/29 15:33:14  brouard
                    440:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    441: 
1.135     brouard   442:   Revision 1.134  2009/10/29 13:18:53  brouard
                    443:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    444: 
1.134     brouard   445:   Revision 1.133  2009/07/06 10:21:25  brouard
                    446:   just nforces
                    447: 
1.133     brouard   448:   Revision 1.132  2009/07/06 08:22:05  brouard
                    449:   Many tings
                    450: 
1.132     brouard   451:   Revision 1.131  2009/06/20 16:22:47  brouard
                    452:   Some dimensions resccaled
                    453: 
1.131     brouard   454:   Revision 1.130  2009/05/26 06:44:34  brouard
                    455:   (Module): Max Covariate is now set to 20 instead of 8. A
                    456:   lot of cleaning with variables initialized to 0. Trying to make
                    457:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    458: 
1.130     brouard   459:   Revision 1.129  2007/08/31 13:49:27  lievre
                    460:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    461: 
1.129     lievre    462:   Revision 1.128  2006/06/30 13:02:05  brouard
                    463:   (Module): Clarifications on computing e.j
                    464: 
1.128     brouard   465:   Revision 1.127  2006/04/28 18:11:50  brouard
                    466:   (Module): Yes the sum of survivors was wrong since
                    467:   imach-114 because nhstepm was no more computed in the age
                    468:   loop. Now we define nhstepma in the age loop.
                    469:   (Module): In order to speed up (in case of numerous covariates) we
                    470:   compute health expectancies (without variances) in a first step
                    471:   and then all the health expectancies with variances or standard
                    472:   deviation (needs data from the Hessian matrices) which slows the
                    473:   computation.
                    474:   In the future we should be able to stop the program is only health
                    475:   expectancies and graph are needed without standard deviations.
                    476: 
1.127     brouard   477:   Revision 1.126  2006/04/28 17:23:28  brouard
                    478:   (Module): Yes the sum of survivors was wrong since
                    479:   imach-114 because nhstepm was no more computed in the age
                    480:   loop. Now we define nhstepma in the age loop.
                    481:   Version 0.98h
                    482: 
1.126     brouard   483:   Revision 1.125  2006/04/04 15:20:31  lievre
                    484:   Errors in calculation of health expectancies. Age was not initialized.
                    485:   Forecasting file added.
                    486: 
                    487:   Revision 1.124  2006/03/22 17:13:53  lievre
                    488:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    489:   The log-likelihood is printed in the log file
                    490: 
                    491:   Revision 1.123  2006/03/20 10:52:43  brouard
                    492:   * imach.c (Module): <title> changed, corresponds to .htm file
                    493:   name. <head> headers where missing.
                    494: 
                    495:   * imach.c (Module): Weights can have a decimal point as for
                    496:   English (a comma might work with a correct LC_NUMERIC environment,
                    497:   otherwise the weight is truncated).
                    498:   Modification of warning when the covariates values are not 0 or
                    499:   1.
                    500:   Version 0.98g
                    501: 
                    502:   Revision 1.122  2006/03/20 09:45:41  brouard
                    503:   (Module): Weights can have a decimal point as for
                    504:   English (a comma might work with a correct LC_NUMERIC environment,
                    505:   otherwise the weight is truncated).
                    506:   Modification of warning when the covariates values are not 0 or
                    507:   1.
                    508:   Version 0.98g
                    509: 
                    510:   Revision 1.121  2006/03/16 17:45:01  lievre
                    511:   * imach.c (Module): Comments concerning covariates added
                    512: 
                    513:   * imach.c (Module): refinements in the computation of lli if
                    514:   status=-2 in order to have more reliable computation if stepm is
                    515:   not 1 month. Version 0.98f
                    516: 
                    517:   Revision 1.120  2006/03/16 15:10:38  lievre
                    518:   (Module): refinements in the computation of lli if
                    519:   status=-2 in order to have more reliable computation if stepm is
                    520:   not 1 month. Version 0.98f
                    521: 
                    522:   Revision 1.119  2006/03/15 17:42:26  brouard
                    523:   (Module): Bug if status = -2, the loglikelihood was
                    524:   computed as likelihood omitting the logarithm. Version O.98e
                    525: 
                    526:   Revision 1.118  2006/03/14 18:20:07  brouard
                    527:   (Module): varevsij Comments added explaining the second
                    528:   table of variances if popbased=1 .
                    529:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    530:   (Module): Function pstamp added
                    531:   (Module): Version 0.98d
                    532: 
                    533:   Revision 1.117  2006/03/14 17:16:22  brouard
                    534:   (Module): varevsij Comments added explaining the second
                    535:   table of variances if popbased=1 .
                    536:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    537:   (Module): Function pstamp added
                    538:   (Module): Version 0.98d
                    539: 
                    540:   Revision 1.116  2006/03/06 10:29:27  brouard
                    541:   (Module): Variance-covariance wrong links and
                    542:   varian-covariance of ej. is needed (Saito).
                    543: 
                    544:   Revision 1.115  2006/02/27 12:17:45  brouard
                    545:   (Module): One freematrix added in mlikeli! 0.98c
                    546: 
                    547:   Revision 1.114  2006/02/26 12:57:58  brouard
                    548:   (Module): Some improvements in processing parameter
                    549:   filename with strsep.
                    550: 
                    551:   Revision 1.113  2006/02/24 14:20:24  brouard
                    552:   (Module): Memory leaks checks with valgrind and:
                    553:   datafile was not closed, some imatrix were not freed and on matrix
                    554:   allocation too.
                    555: 
                    556:   Revision 1.112  2006/01/30 09:55:26  brouard
                    557:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    558: 
                    559:   Revision 1.111  2006/01/25 20:38:18  brouard
                    560:   (Module): Lots of cleaning and bugs added (Gompertz)
                    561:   (Module): Comments can be added in data file. Missing date values
                    562:   can be a simple dot '.'.
                    563: 
                    564:   Revision 1.110  2006/01/25 00:51:50  brouard
                    565:   (Module): Lots of cleaning and bugs added (Gompertz)
                    566: 
                    567:   Revision 1.109  2006/01/24 19:37:15  brouard
                    568:   (Module): Comments (lines starting with a #) are allowed in data.
                    569: 
                    570:   Revision 1.108  2006/01/19 18:05:42  lievre
                    571:   Gnuplot problem appeared...
                    572:   To be fixed
                    573: 
                    574:   Revision 1.107  2006/01/19 16:20:37  brouard
                    575:   Test existence of gnuplot in imach path
                    576: 
                    577:   Revision 1.106  2006/01/19 13:24:36  brouard
                    578:   Some cleaning and links added in html output
                    579: 
                    580:   Revision 1.105  2006/01/05 20:23:19  lievre
                    581:   *** empty log message ***
                    582: 
                    583:   Revision 1.104  2005/09/30 16:11:43  lievre
                    584:   (Module): sump fixed, loop imx fixed, and simplifications.
                    585:   (Module): If the status is missing at the last wave but we know
                    586:   that the person is alive, then we can code his/her status as -2
                    587:   (instead of missing=-1 in earlier versions) and his/her
                    588:   contributions to the likelihood is 1 - Prob of dying from last
                    589:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    590:   the healthy state at last known wave). Version is 0.98
                    591: 
                    592:   Revision 1.103  2005/09/30 15:54:49  lievre
                    593:   (Module): sump fixed, loop imx fixed, and simplifications.
                    594: 
                    595:   Revision 1.102  2004/09/15 17:31:30  brouard
                    596:   Add the possibility to read data file including tab characters.
                    597: 
                    598:   Revision 1.101  2004/09/15 10:38:38  brouard
                    599:   Fix on curr_time
                    600: 
                    601:   Revision 1.100  2004/07/12 18:29:06  brouard
                    602:   Add version for Mac OS X. Just define UNIX in Makefile
                    603: 
                    604:   Revision 1.99  2004/06/05 08:57:40  brouard
                    605:   *** empty log message ***
                    606: 
                    607:   Revision 1.98  2004/05/16 15:05:56  brouard
                    608:   New version 0.97 . First attempt to estimate force of mortality
                    609:   directly from the data i.e. without the need of knowing the health
                    610:   state at each age, but using a Gompertz model: log u =a + b*age .
                    611:   This is the basic analysis of mortality and should be done before any
                    612:   other analysis, in order to test if the mortality estimated from the
                    613:   cross-longitudinal survey is different from the mortality estimated
                    614:   from other sources like vital statistic data.
                    615: 
                    616:   The same imach parameter file can be used but the option for mle should be -3.
                    617: 
1.133     brouard   618:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   619:   former routines in order to include the new code within the former code.
                    620: 
                    621:   The output is very simple: only an estimate of the intercept and of
                    622:   the slope with 95% confident intervals.
                    623: 
                    624:   Current limitations:
                    625:   A) Even if you enter covariates, i.e. with the
                    626:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    627:   B) There is no computation of Life Expectancy nor Life Table.
                    628: 
                    629:   Revision 1.97  2004/02/20 13:25:42  lievre
                    630:   Version 0.96d. Population forecasting command line is (temporarily)
                    631:   suppressed.
                    632: 
                    633:   Revision 1.96  2003/07/15 15:38:55  brouard
                    634:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    635:   rewritten within the same printf. Workaround: many printfs.
                    636: 
                    637:   Revision 1.95  2003/07/08 07:54:34  brouard
                    638:   * imach.c (Repository):
                    639:   (Repository): Using imachwizard code to output a more meaningful covariance
                    640:   matrix (cov(a12,c31) instead of numbers.
                    641: 
                    642:   Revision 1.94  2003/06/27 13:00:02  brouard
                    643:   Just cleaning
                    644: 
                    645:   Revision 1.93  2003/06/25 16:33:55  brouard
                    646:   (Module): On windows (cygwin) function asctime_r doesn't
                    647:   exist so I changed back to asctime which exists.
                    648:   (Module): Version 0.96b
                    649: 
                    650:   Revision 1.92  2003/06/25 16:30:45  brouard
                    651:   (Module): On windows (cygwin) function asctime_r doesn't
                    652:   exist so I changed back to asctime which exists.
                    653: 
                    654:   Revision 1.91  2003/06/25 15:30:29  brouard
                    655:   * imach.c (Repository): Duplicated warning errors corrected.
                    656:   (Repository): Elapsed time after each iteration is now output. It
                    657:   helps to forecast when convergence will be reached. Elapsed time
                    658:   is stamped in powell.  We created a new html file for the graphs
                    659:   concerning matrix of covariance. It has extension -cov.htm.
                    660: 
                    661:   Revision 1.90  2003/06/24 12:34:15  brouard
                    662:   (Module): Some bugs corrected for windows. Also, when
                    663:   mle=-1 a template is output in file "or"mypar.txt with the design
                    664:   of the covariance matrix to be input.
                    665: 
                    666:   Revision 1.89  2003/06/24 12:30:52  brouard
                    667:   (Module): Some bugs corrected for windows. Also, when
                    668:   mle=-1 a template is output in file "or"mypar.txt with the design
                    669:   of the covariance matrix to be input.
                    670: 
                    671:   Revision 1.88  2003/06/23 17:54:56  brouard
                    672:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    673: 
                    674:   Revision 1.87  2003/06/18 12:26:01  brouard
                    675:   Version 0.96
                    676: 
                    677:   Revision 1.86  2003/06/17 20:04:08  brouard
                    678:   (Module): Change position of html and gnuplot routines and added
                    679:   routine fileappend.
                    680: 
                    681:   Revision 1.85  2003/06/17 13:12:43  brouard
                    682:   * imach.c (Repository): Check when date of death was earlier that
                    683:   current date of interview. It may happen when the death was just
                    684:   prior to the death. In this case, dh was negative and likelihood
                    685:   was wrong (infinity). We still send an "Error" but patch by
                    686:   assuming that the date of death was just one stepm after the
                    687:   interview.
                    688:   (Repository): Because some people have very long ID (first column)
                    689:   we changed int to long in num[] and we added a new lvector for
                    690:   memory allocation. But we also truncated to 8 characters (left
                    691:   truncation)
                    692:   (Repository): No more line truncation errors.
                    693: 
                    694:   Revision 1.84  2003/06/13 21:44:43  brouard
                    695:   * imach.c (Repository): Replace "freqsummary" at a correct
                    696:   place. It differs from routine "prevalence" which may be called
                    697:   many times. Probs is memory consuming and must be used with
                    698:   parcimony.
                    699:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    700: 
                    701:   Revision 1.83  2003/06/10 13:39:11  lievre
                    702:   *** empty log message ***
                    703: 
                    704:   Revision 1.82  2003/06/05 15:57:20  brouard
                    705:   Add log in  imach.c and  fullversion number is now printed.
                    706: 
                    707: */
                    708: /*
                    709:    Interpolated Markov Chain
                    710: 
                    711:   Short summary of the programme:
                    712:   
1.227     brouard   713:   This program computes Healthy Life Expectancies or State-specific
                    714:   (if states aren't health statuses) Expectancies from
                    715:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    716: 
                    717:   -1- a first survey ("cross") where individuals from different ages
                    718:   are interviewed on their health status or degree of disability (in
                    719:   the case of a health survey which is our main interest)
                    720: 
                    721:   -2- at least a second wave of interviews ("longitudinal") which
                    722:   measure each change (if any) in individual health status.  Health
                    723:   expectancies are computed from the time spent in each health state
                    724:   according to a model. More health states you consider, more time is
                    725:   necessary to reach the Maximum Likelihood of the parameters involved
                    726:   in the model.  The simplest model is the multinomial logistic model
                    727:   where pij is the probability to be observed in state j at the second
                    728:   wave conditional to be observed in state i at the first
                    729:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    730:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    731:   have a more complex model than "constant and age", you should modify
                    732:   the program where the markup *Covariates have to be included here
                    733:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   734:   convergence.
                    735: 
                    736:   The advantage of this computer programme, compared to a simple
                    737:   multinomial logistic model, is clear when the delay between waves is not
                    738:   identical for each individual. Also, if a individual missed an
                    739:   intermediate interview, the information is lost, but taken into
                    740:   account using an interpolation or extrapolation.  
                    741: 
                    742:   hPijx is the probability to be observed in state i at age x+h
                    743:   conditional to the observed state i at age x. The delay 'h' can be
                    744:   split into an exact number (nh*stepm) of unobserved intermediate
                    745:   states. This elementary transition (by month, quarter,
                    746:   semester or year) is modelled as a multinomial logistic.  The hPx
                    747:   matrix is simply the matrix product of nh*stepm elementary matrices
                    748:   and the contribution of each individual to the likelihood is simply
                    749:   hPijx.
                    750: 
                    751:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   752:   of the life expectancies. It also computes the period (stable) prevalence.
                    753: 
                    754: Back prevalence and projections:
1.227     brouard   755: 
                    756:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    757:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    758:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    759:    mobilavproj)
                    760: 
                    761:     Computes the back prevalence limit for any combination of
                    762:     covariate values k at any age between ageminpar and agemaxpar and
                    763:     returns it in **bprlim. In the loops,
                    764: 
                    765:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    766:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    767: 
                    768:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   769:    Computes for any combination of covariates k and any age between bage and fage 
                    770:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    771:                        oldm=oldms;savm=savms;
1.227     brouard   772: 
                    773:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);
1.218     brouard   774:      Computes the transition matrix starting at age 'age' over
                    775:      'nhstepm*hstepm*stepm' months (i.e. until
                    776:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   777:      nhstepm*hstepm matrices. 
                    778: 
                    779:      Returns p3mat[i][j][h] after calling
                    780:      p3mat[i][j][h]=matprod2(newm,
                    781:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    782:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    783:      oldm);
1.226     brouard   784: 
                    785: Important routines
                    786: 
                    787: - func (or funcone), computes logit (pij) distinguishing
                    788:   o fixed variables (single or product dummies or quantitative);
                    789:   o varying variables by:
                    790:    (1) wave (single, product dummies, quantitative), 
                    791:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    792:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    793:        % varying dummy (not done) or quantitative (not done);
                    794: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    795:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    796: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    797:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    798:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   799: 
1.226     brouard   800: 
                    801:   
1.133     brouard   802:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    803:            Institut national d'études démographiques, Paris.
1.126     brouard   804:   This software have been partly granted by Euro-REVES, a concerted action
                    805:   from the European Union.
                    806:   It is copyrighted identically to a GNU software product, ie programme and
                    807:   software can be distributed freely for non commercial use. Latest version
                    808:   can be accessed at http://euroreves.ined.fr/imach .
                    809: 
                    810:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    811:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    812:   
                    813:   **********************************************************************/
                    814: /*
                    815:   main
                    816:   read parameterfile
                    817:   read datafile
                    818:   concatwav
                    819:   freqsummary
                    820:   if (mle >= 1)
                    821:     mlikeli
                    822:   print results files
                    823:   if mle==1 
                    824:      computes hessian
                    825:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    826:       begin-prev-date,...
                    827:   open gnuplot file
                    828:   open html file
1.145     brouard   829:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    830:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    831:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    832:     freexexit2 possible for memory heap.
                    833: 
                    834:   h Pij x                         | pij_nom  ficrestpij
                    835:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    836:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    837:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    838: 
                    839:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    840:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    841:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    842:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    843:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    844: 
1.126     brouard   845:   forecasting if prevfcast==1 prevforecast call prevalence()
                    846:   health expectancies
                    847:   Variance-covariance of DFLE
                    848:   prevalence()
                    849:    movingaverage()
                    850:   varevsij() 
                    851:   if popbased==1 varevsij(,popbased)
                    852:   total life expectancies
                    853:   Variance of period (stable) prevalence
                    854:  end
                    855: */
                    856: 
1.187     brouard   857: /* #define DEBUG */
                    858: /* #define DEBUGBRENT */
1.203     brouard   859: /* #define DEBUGLINMIN */
                    860: /* #define DEBUGHESS */
                    861: #define DEBUGHESSIJ
1.224     brouard   862: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   863: #define POWELL /* Instead of NLOPT */
1.224     brouard   864: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   865: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    866: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   867: 
                    868: #include <math.h>
                    869: #include <stdio.h>
                    870: #include <stdlib.h>
                    871: #include <string.h>
1.226     brouard   872: #include <ctype.h>
1.159     brouard   873: 
                    874: #ifdef _WIN32
                    875: #include <io.h>
1.172     brouard   876: #include <windows.h>
                    877: #include <tchar.h>
1.159     brouard   878: #else
1.126     brouard   879: #include <unistd.h>
1.159     brouard   880: #endif
1.126     brouard   881: 
                    882: #include <limits.h>
                    883: #include <sys/types.h>
1.171     brouard   884: 
                    885: #if defined(__GNUC__)
                    886: #include <sys/utsname.h> /* Doesn't work on Windows */
                    887: #endif
                    888: 
1.126     brouard   889: #include <sys/stat.h>
                    890: #include <errno.h>
1.159     brouard   891: /* extern int errno; */
1.126     brouard   892: 
1.157     brouard   893: /* #ifdef LINUX */
                    894: /* #include <time.h> */
                    895: /* #include "timeval.h" */
                    896: /* #else */
                    897: /* #include <sys/time.h> */
                    898: /* #endif */
                    899: 
1.126     brouard   900: #include <time.h>
                    901: 
1.136     brouard   902: #ifdef GSL
                    903: #include <gsl/gsl_errno.h>
                    904: #include <gsl/gsl_multimin.h>
                    905: #endif
                    906: 
1.167     brouard   907: 
1.162     brouard   908: #ifdef NLOPT
                    909: #include <nlopt.h>
                    910: typedef struct {
                    911:   double (* function)(double [] );
                    912: } myfunc_data ;
                    913: #endif
                    914: 
1.126     brouard   915: /* #include <libintl.h> */
                    916: /* #define _(String) gettext (String) */
                    917: 
1.251   ! brouard   918: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   919: 
                    920: #define GNUPLOTPROGRAM "gnuplot"
                    921: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    922: #define FILENAMELENGTH 132
                    923: 
                    924: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    925: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    926: 
1.144     brouard   927: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    928: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   929: 
                    930: #define NINTERVMAX 8
1.144     brouard   931: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    932: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    933: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   934: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   935: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    936: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   937: #define MAXN 20000
1.144     brouard   938: #define YEARM 12. /**< Number of months per year */
1.218     brouard   939: /* #define AGESUP 130 */
                    940: #define AGESUP 150
                    941: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard   942: #define AGEBASE 40
1.194     brouard   943: #define AGEOVERFLOW 1.e20
1.164     brouard   944: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard   945: #ifdef _WIN32
                    946: #define DIRSEPARATOR '\\'
                    947: #define CHARSEPARATOR "\\"
                    948: #define ODIRSEPARATOR '/'
                    949: #else
1.126     brouard   950: #define DIRSEPARATOR '/'
                    951: #define CHARSEPARATOR "/"
                    952: #define ODIRSEPARATOR '\\'
                    953: #endif
                    954: 
1.251   ! brouard   955: /* $Id: imach.c,v 1.250 2016/09/08 16:07:27 brouard Exp $ */
1.126     brouard   956: /* $State: Exp $ */
1.196     brouard   957: #include "version.h"
                    958: char version[]=__IMACH_VERSION__;
1.224     brouard   959: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.251   ! brouard   960: char fullversion[]="$Revision: 1.250 $ $Date: 2016/09/08 16:07:27 $"; 
1.126     brouard   961: char strstart[80];
                    962: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard   963: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard   964: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard   965: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                    966: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                    967: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard   968: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                    969: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard   970: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                    971: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                    972: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard   973: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                    974: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard   975: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard   976: int nsd=0; /**< Total number of single dummy variables (output) */
                    977: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard   978: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard   979: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard   980: int ntveff=0; /**< ntveff number of effective time varying variables */
                    981: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard   982: int cptcov=0; /* Working variable */
1.218     brouard   983: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard   984: int npar=NPARMAX;
                    985: int nlstate=2; /* Number of live states */
                    986: int ndeath=1; /* Number of dead states */
1.130     brouard   987: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard   988: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard   989: int popbased=0;
                    990: 
                    991: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard   992: int maxwav=0; /* Maxim number of waves */
                    993: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                    994: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                    995: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard   996:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard   997: int mle=1, weightopt=0;
1.126     brouard   998: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                    999: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1000: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1001:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1002: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1003: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1004: 
1.130     brouard  1005: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1006: double **matprod2(); /* test */
1.126     brouard  1007: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1008: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1009: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1010: 
1.136     brouard  1011: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1012: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1013: FILE *ficlog, *ficrespow;
1.130     brouard  1014: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1015: double fretone; /* Only one call to likelihood */
1.130     brouard  1016: long ipmx=0; /* Number of contributions */
1.126     brouard  1017: double sw; /* Sum of weights */
                   1018: char filerespow[FILENAMELENGTH];
                   1019: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1020: FILE *ficresilk;
                   1021: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1022: FILE *ficresprobmorprev;
                   1023: FILE *fichtm, *fichtmcov; /* Html File */
                   1024: FILE *ficreseij;
                   1025: char filerese[FILENAMELENGTH];
                   1026: FILE *ficresstdeij;
                   1027: char fileresstde[FILENAMELENGTH];
                   1028: FILE *ficrescveij;
                   1029: char filerescve[FILENAMELENGTH];
                   1030: FILE  *ficresvij;
                   1031: char fileresv[FILENAMELENGTH];
                   1032: FILE  *ficresvpl;
                   1033: char fileresvpl[FILENAMELENGTH];
                   1034: char title[MAXLINE];
1.234     brouard  1035: char model[MAXLINE]; /**< The model line */
1.217     brouard  1036: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1037: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1038: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1039: char command[FILENAMELENGTH];
                   1040: int  outcmd=0;
                   1041: 
1.217     brouard  1042: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1043: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1044: char filelog[FILENAMELENGTH]; /* Log file */
                   1045: char filerest[FILENAMELENGTH];
                   1046: char fileregp[FILENAMELENGTH];
                   1047: char popfile[FILENAMELENGTH];
                   1048: 
                   1049: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1050: 
1.157     brouard  1051: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1052: /* struct timezone tzp; */
                   1053: /* extern int gettimeofday(); */
                   1054: struct tm tml, *gmtime(), *localtime();
                   1055: 
                   1056: extern time_t time();
                   1057: 
                   1058: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1059: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1060: struct tm tm;
                   1061: 
1.126     brouard  1062: char strcurr[80], strfor[80];
                   1063: 
                   1064: char *endptr;
                   1065: long lval;
                   1066: double dval;
                   1067: 
                   1068: #define NR_END 1
                   1069: #define FREE_ARG char*
                   1070: #define FTOL 1.0e-10
                   1071: 
                   1072: #define NRANSI 
1.240     brouard  1073: #define ITMAX 200
                   1074: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1075: 
                   1076: #define TOL 2.0e-4 
                   1077: 
                   1078: #define CGOLD 0.3819660 
                   1079: #define ZEPS 1.0e-10 
                   1080: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1081: 
                   1082: #define GOLD 1.618034 
                   1083: #define GLIMIT 100.0 
                   1084: #define TINY 1.0e-20 
                   1085: 
                   1086: static double maxarg1,maxarg2;
                   1087: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1088: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1089:   
                   1090: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1091: #define rint(a) floor(a+0.5)
1.166     brouard  1092: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1093: #define mytinydouble 1.0e-16
1.166     brouard  1094: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1095: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1096: /* static double dsqrarg; */
                   1097: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1098: static double sqrarg;
                   1099: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1100: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1101: int agegomp= AGEGOMP;
                   1102: 
                   1103: int imx; 
                   1104: int stepm=1;
                   1105: /* Stepm, step in month: minimum step interpolation*/
                   1106: 
                   1107: int estepm;
                   1108: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1109: 
                   1110: int m,nb;
                   1111: long *num;
1.197     brouard  1112: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1113: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1114:                   covariate for which somebody answered excluding 
                   1115:                   undefined. Usually 2: 0 and 1. */
                   1116: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1117:                             covariate for which somebody answered including 
                   1118:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1119: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1120: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1121: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1122: double *ageexmed,*agecens;
                   1123: double dateintmean=0;
                   1124: 
                   1125: double *weight;
                   1126: int **s; /* Status */
1.141     brouard  1127: double *agedc;
1.145     brouard  1128: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1129:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1130:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.225     brouard  1131: double **coqvar; /* Fixed quantitative covariate iqv */
                   1132: double ***cotvar; /* Time varying covariate itv */
                   1133: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1134: double  idx; 
                   1135: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1136: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1137: /*k          1  2   3   4     5    6    7     8    9 */
                   1138: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1139: /* Tndvar[k]    1   2   3               4          5 */
                   1140: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1141: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1142: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1143: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1144: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1145: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1146: /* Tprod[i]=k           4               7            */
                   1147: /* Tage[i]=k                  5               8      */
                   1148: /* */
                   1149: /* Type                    */
                   1150: /* V         1  2  3  4  5 */
                   1151: /*           F  F  V  V  V */
                   1152: /*           D  Q  D  D  Q */
                   1153: /*                         */
                   1154: int *TvarsD;
                   1155: int *TvarsDind;
                   1156: int *TvarsQ;
                   1157: int *TvarsQind;
                   1158: 
1.235     brouard  1159: #define MAXRESULTLINES 10
                   1160: int nresult=0;
                   1161: int TKresult[MAXRESULTLINES];
1.237     brouard  1162: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1163: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1164: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1165: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1166: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1167: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1168: 
1.234     brouard  1169: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1170: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1171: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1172: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1173: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1174: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1175: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1176: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1177: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1178: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1179: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1180: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1181: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1182: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1183: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1184: 
1.230     brouard  1185: int *Tvarsel; /**< Selected covariates for output */
                   1186: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1187: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1188: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1189: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1190: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1191: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1192: int *Tage;
1.227     brouard  1193: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1194: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1195: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1196: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1197: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1198: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1199: int **Tvard;
                   1200: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1201: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1202: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1203:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1204:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1205: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1206: double *lsurv, *lpop, *tpop;
                   1207: 
1.231     brouard  1208: #define FD 1; /* Fixed dummy covariate */
                   1209: #define FQ 2; /* Fixed quantitative covariate */
                   1210: #define FP 3; /* Fixed product covariate */
                   1211: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1212: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1213: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1214: #define VD 10; /* Varying dummy covariate */
                   1215: #define VQ 11; /* Varying quantitative covariate */
                   1216: #define VP 12; /* Varying product covariate */
                   1217: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1218: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1219: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1220: #define APFD 16; /* Age product * fixed dummy covariate */
                   1221: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1222: #define APVD 18; /* Age product * varying dummy covariate */
                   1223: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1224: 
                   1225: #define FTYPE 1; /* Fixed covariate */
                   1226: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1227: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1228: 
                   1229: struct kmodel{
                   1230:        int maintype; /* main type */
                   1231:        int subtype; /* subtype */
                   1232: };
                   1233: struct kmodel modell[NCOVMAX];
                   1234: 
1.143     brouard  1235: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1236: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1237: 
                   1238: /**************** split *************************/
                   1239: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1240: {
                   1241:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1242:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1243:   */ 
                   1244:   char *ss;                            /* pointer */
1.186     brouard  1245:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1246: 
                   1247:   l1 = strlen(path );                  /* length of path */
                   1248:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1249:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1250:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1251:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1252:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1253:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1254:     /* get current working directory */
                   1255:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1256: #ifdef WIN32
                   1257:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1258: #else
                   1259:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1260: #endif
1.126     brouard  1261:       return( GLOCK_ERROR_GETCWD );
                   1262:     }
                   1263:     /* got dirc from getcwd*/
                   1264:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1265:   } else {                             /* strip directory from path */
1.126     brouard  1266:     ss++;                              /* after this, the filename */
                   1267:     l2 = strlen( ss );                 /* length of filename */
                   1268:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1269:     strcpy( name, ss );                /* save file name */
                   1270:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1271:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1272:     printf(" DIRC2 = %s \n",dirc);
                   1273:   }
                   1274:   /* We add a separator at the end of dirc if not exists */
                   1275:   l1 = strlen( dirc );                 /* length of directory */
                   1276:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1277:     dirc[l1] =  DIRSEPARATOR;
                   1278:     dirc[l1+1] = 0; 
                   1279:     printf(" DIRC3 = %s \n",dirc);
                   1280:   }
                   1281:   ss = strrchr( name, '.' );           /* find last / */
                   1282:   if (ss >0){
                   1283:     ss++;
                   1284:     strcpy(ext,ss);                    /* save extension */
                   1285:     l1= strlen( name);
                   1286:     l2= strlen(ss)+1;
                   1287:     strncpy( finame, name, l1-l2);
                   1288:     finame[l1-l2]= 0;
                   1289:   }
                   1290: 
                   1291:   return( 0 );                         /* we're done */
                   1292: }
                   1293: 
                   1294: 
                   1295: /******************************************/
                   1296: 
                   1297: void replace_back_to_slash(char *s, char*t)
                   1298: {
                   1299:   int i;
                   1300:   int lg=0;
                   1301:   i=0;
                   1302:   lg=strlen(t);
                   1303:   for(i=0; i<= lg; i++) {
                   1304:     (s[i] = t[i]);
                   1305:     if (t[i]== '\\') s[i]='/';
                   1306:   }
                   1307: }
                   1308: 
1.132     brouard  1309: char *trimbb(char *out, char *in)
1.137     brouard  1310: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1311:   char *s;
                   1312:   s=out;
                   1313:   while (*in != '\0'){
1.137     brouard  1314:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1315:       in++;
                   1316:     }
                   1317:     *out++ = *in++;
                   1318:   }
                   1319:   *out='\0';
                   1320:   return s;
                   1321: }
                   1322: 
1.187     brouard  1323: /* char *substrchaine(char *out, char *in, char *chain) */
                   1324: /* { */
                   1325: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1326: /*   char *s, *t; */
                   1327: /*   t=in;s=out; */
                   1328: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1329: /*     *out++ = *in++; */
                   1330: /*   } */
                   1331: 
                   1332: /*   /\* *in matches *chain *\/ */
                   1333: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1334: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1335: /*   } */
                   1336: /*   in--; chain--; */
                   1337: /*   while ( (*in != '\0')){ */
                   1338: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1339: /*     *out++ = *in++; */
                   1340: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1341: /*   } */
                   1342: /*   *out='\0'; */
                   1343: /*   out=s; */
                   1344: /*   return out; */
                   1345: /* } */
                   1346: char *substrchaine(char *out, char *in, char *chain)
                   1347: {
                   1348:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1349:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1350: 
                   1351:   char *strloc;
                   1352: 
                   1353:   strcpy (out, in); 
                   1354:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1355:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1356:   if(strloc != NULL){ 
                   1357:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1358:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1359:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1360:   }
                   1361:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1362:   return out;
                   1363: }
                   1364: 
                   1365: 
1.145     brouard  1366: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1367: {
1.187     brouard  1368:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1369:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1370:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1371:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1372:   */
1.160     brouard  1373:   char *s, *t;
1.145     brouard  1374:   t=in;s=in;
                   1375:   while ((*in != occ) && (*in != '\0')){
                   1376:     *alocc++ = *in++;
                   1377:   }
                   1378:   if( *in == occ){
                   1379:     *(alocc)='\0';
                   1380:     s=++in;
                   1381:   }
                   1382:  
                   1383:   if (s == t) {/* occ not found */
                   1384:     *(alocc-(in-s))='\0';
                   1385:     in=s;
                   1386:   }
                   1387:   while ( *in != '\0'){
                   1388:     *blocc++ = *in++;
                   1389:   }
                   1390: 
                   1391:   *blocc='\0';
                   1392:   return t;
                   1393: }
1.137     brouard  1394: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1395: {
1.187     brouard  1396:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1397:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1398:      gives blocc="abcdef2ghi" and alocc="j".
                   1399:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1400:   */
                   1401:   char *s, *t;
                   1402:   t=in;s=in;
                   1403:   while (*in != '\0'){
                   1404:     while( *in == occ){
                   1405:       *blocc++ = *in++;
                   1406:       s=in;
                   1407:     }
                   1408:     *blocc++ = *in++;
                   1409:   }
                   1410:   if (s == t) /* occ not found */
                   1411:     *(blocc-(in-s))='\0';
                   1412:   else
                   1413:     *(blocc-(in-s)-1)='\0';
                   1414:   in=s;
                   1415:   while ( *in != '\0'){
                   1416:     *alocc++ = *in++;
                   1417:   }
                   1418: 
                   1419:   *alocc='\0';
                   1420:   return s;
                   1421: }
                   1422: 
1.126     brouard  1423: int nbocc(char *s, char occ)
                   1424: {
                   1425:   int i,j=0;
                   1426:   int lg=20;
                   1427:   i=0;
                   1428:   lg=strlen(s);
                   1429:   for(i=0; i<= lg; i++) {
1.234     brouard  1430:     if  (s[i] == occ ) j++;
1.126     brouard  1431:   }
                   1432:   return j;
                   1433: }
                   1434: 
1.137     brouard  1435: /* void cutv(char *u,char *v, char*t, char occ) */
                   1436: /* { */
                   1437: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1438: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1439: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1440: /*   int i,lg,j,p=0; */
                   1441: /*   i=0; */
                   1442: /*   lg=strlen(t); */
                   1443: /*   for(j=0; j<=lg-1; j++) { */
                   1444: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1445: /*   } */
1.126     brouard  1446: 
1.137     brouard  1447: /*   for(j=0; j<p; j++) { */
                   1448: /*     (u[j] = t[j]); */
                   1449: /*   } */
                   1450: /*      u[p]='\0'; */
1.126     brouard  1451: 
1.137     brouard  1452: /*    for(j=0; j<= lg; j++) { */
                   1453: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1454: /*   } */
                   1455: /* } */
1.126     brouard  1456: 
1.160     brouard  1457: #ifdef _WIN32
                   1458: char * strsep(char **pp, const char *delim)
                   1459: {
                   1460:   char *p, *q;
                   1461:          
                   1462:   if ((p = *pp) == NULL)
                   1463:     return 0;
                   1464:   if ((q = strpbrk (p, delim)) != NULL)
                   1465:   {
                   1466:     *pp = q + 1;
                   1467:     *q = '\0';
                   1468:   }
                   1469:   else
                   1470:     *pp = 0;
                   1471:   return p;
                   1472: }
                   1473: #endif
                   1474: 
1.126     brouard  1475: /********************** nrerror ********************/
                   1476: 
                   1477: void nrerror(char error_text[])
                   1478: {
                   1479:   fprintf(stderr,"ERREUR ...\n");
                   1480:   fprintf(stderr,"%s\n",error_text);
                   1481:   exit(EXIT_FAILURE);
                   1482: }
                   1483: /*********************** vector *******************/
                   1484: double *vector(int nl, int nh)
                   1485: {
                   1486:   double *v;
                   1487:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1488:   if (!v) nrerror("allocation failure in vector");
                   1489:   return v-nl+NR_END;
                   1490: }
                   1491: 
                   1492: /************************ free vector ******************/
                   1493: void free_vector(double*v, int nl, int nh)
                   1494: {
                   1495:   free((FREE_ARG)(v+nl-NR_END));
                   1496: }
                   1497: 
                   1498: /************************ivector *******************************/
                   1499: int *ivector(long nl,long nh)
                   1500: {
                   1501:   int *v;
                   1502:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1503:   if (!v) nrerror("allocation failure in ivector");
                   1504:   return v-nl+NR_END;
                   1505: }
                   1506: 
                   1507: /******************free ivector **************************/
                   1508: void free_ivector(int *v, long nl, long nh)
                   1509: {
                   1510:   free((FREE_ARG)(v+nl-NR_END));
                   1511: }
                   1512: 
                   1513: /************************lvector *******************************/
                   1514: long *lvector(long nl,long nh)
                   1515: {
                   1516:   long *v;
                   1517:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1518:   if (!v) nrerror("allocation failure in ivector");
                   1519:   return v-nl+NR_END;
                   1520: }
                   1521: 
                   1522: /******************free lvector **************************/
                   1523: void free_lvector(long *v, long nl, long nh)
                   1524: {
                   1525:   free((FREE_ARG)(v+nl-NR_END));
                   1526: }
                   1527: 
                   1528: /******************* imatrix *******************************/
                   1529: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1530:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1531: { 
                   1532:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1533:   int **m; 
                   1534:   
                   1535:   /* allocate pointers to rows */ 
                   1536:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1537:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1538:   m += NR_END; 
                   1539:   m -= nrl; 
                   1540:   
                   1541:   
                   1542:   /* allocate rows and set pointers to them */ 
                   1543:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1544:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1545:   m[nrl] += NR_END; 
                   1546:   m[nrl] -= ncl; 
                   1547:   
                   1548:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1549:   
                   1550:   /* return pointer to array of pointers to rows */ 
                   1551:   return m; 
                   1552: } 
                   1553: 
                   1554: /****************** free_imatrix *************************/
                   1555: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1556:       int **m;
                   1557:       long nch,ncl,nrh,nrl; 
                   1558:      /* free an int matrix allocated by imatrix() */ 
                   1559: { 
                   1560:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1561:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1562: } 
                   1563: 
                   1564: /******************* matrix *******************************/
                   1565: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1566: {
                   1567:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1568:   double **m;
                   1569: 
                   1570:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1571:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1572:   m += NR_END;
                   1573:   m -= nrl;
                   1574: 
                   1575:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1576:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1577:   m[nrl] += NR_END;
                   1578:   m[nrl] -= ncl;
                   1579: 
                   1580:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1581:   return m;
1.145     brouard  1582:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1583: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1584: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1585:    */
                   1586: }
                   1587: 
                   1588: /*************************free matrix ************************/
                   1589: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1590: {
                   1591:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1592:   free((FREE_ARG)(m+nrl-NR_END));
                   1593: }
                   1594: 
                   1595: /******************* ma3x *******************************/
                   1596: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1597: {
                   1598:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1599:   double ***m;
                   1600: 
                   1601:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1602:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1603:   m += NR_END;
                   1604:   m -= nrl;
                   1605: 
                   1606:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1607:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1608:   m[nrl] += NR_END;
                   1609:   m[nrl] -= ncl;
                   1610: 
                   1611:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1612: 
                   1613:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1614:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1615:   m[nrl][ncl] += NR_END;
                   1616:   m[nrl][ncl] -= nll;
                   1617:   for (j=ncl+1; j<=nch; j++) 
                   1618:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1619:   
                   1620:   for (i=nrl+1; i<=nrh; i++) {
                   1621:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1622:     for (j=ncl+1; j<=nch; j++) 
                   1623:       m[i][j]=m[i][j-1]+nlay;
                   1624:   }
                   1625:   return m; 
                   1626:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1627:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1628:   */
                   1629: }
                   1630: 
                   1631: /*************************free ma3x ************************/
                   1632: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1633: {
                   1634:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1635:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1636:   free((FREE_ARG)(m+nrl-NR_END));
                   1637: }
                   1638: 
                   1639: /*************** function subdirf ***********/
                   1640: char *subdirf(char fileres[])
                   1641: {
                   1642:   /* Caution optionfilefiname is hidden */
                   1643:   strcpy(tmpout,optionfilefiname);
                   1644:   strcat(tmpout,"/"); /* Add to the right */
                   1645:   strcat(tmpout,fileres);
                   1646:   return tmpout;
                   1647: }
                   1648: 
                   1649: /*************** function subdirf2 ***********/
                   1650: char *subdirf2(char fileres[], char *preop)
                   1651: {
                   1652:   
                   1653:   /* Caution optionfilefiname is hidden */
                   1654:   strcpy(tmpout,optionfilefiname);
                   1655:   strcat(tmpout,"/");
                   1656:   strcat(tmpout,preop);
                   1657:   strcat(tmpout,fileres);
                   1658:   return tmpout;
                   1659: }
                   1660: 
                   1661: /*************** function subdirf3 ***********/
                   1662: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1663: {
                   1664:   
                   1665:   /* Caution optionfilefiname is hidden */
                   1666:   strcpy(tmpout,optionfilefiname);
                   1667:   strcat(tmpout,"/");
                   1668:   strcat(tmpout,preop);
                   1669:   strcat(tmpout,preop2);
                   1670:   strcat(tmpout,fileres);
                   1671:   return tmpout;
                   1672: }
1.213     brouard  1673:  
                   1674: /*************** function subdirfext ***********/
                   1675: char *subdirfext(char fileres[], char *preop, char *postop)
                   1676: {
                   1677:   
                   1678:   strcpy(tmpout,preop);
                   1679:   strcat(tmpout,fileres);
                   1680:   strcat(tmpout,postop);
                   1681:   return tmpout;
                   1682: }
1.126     brouard  1683: 
1.213     brouard  1684: /*************** function subdirfext3 ***********/
                   1685: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1686: {
                   1687:   
                   1688:   /* Caution optionfilefiname is hidden */
                   1689:   strcpy(tmpout,optionfilefiname);
                   1690:   strcat(tmpout,"/");
                   1691:   strcat(tmpout,preop);
                   1692:   strcat(tmpout,fileres);
                   1693:   strcat(tmpout,postop);
                   1694:   return tmpout;
                   1695: }
                   1696:  
1.162     brouard  1697: char *asc_diff_time(long time_sec, char ascdiff[])
                   1698: {
                   1699:   long sec_left, days, hours, minutes;
                   1700:   days = (time_sec) / (60*60*24);
                   1701:   sec_left = (time_sec) % (60*60*24);
                   1702:   hours = (sec_left) / (60*60) ;
                   1703:   sec_left = (sec_left) %(60*60);
                   1704:   minutes = (sec_left) /60;
                   1705:   sec_left = (sec_left) % (60);
                   1706:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1707:   return ascdiff;
                   1708: }
                   1709: 
1.126     brouard  1710: /***************** f1dim *************************/
                   1711: extern int ncom; 
                   1712: extern double *pcom,*xicom;
                   1713: extern double (*nrfunc)(double []); 
                   1714:  
                   1715: double f1dim(double x) 
                   1716: { 
                   1717:   int j; 
                   1718:   double f;
                   1719:   double *xt; 
                   1720:  
                   1721:   xt=vector(1,ncom); 
                   1722:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1723:   f=(*nrfunc)(xt); 
                   1724:   free_vector(xt,1,ncom); 
                   1725:   return f; 
                   1726: } 
                   1727: 
                   1728: /*****************brent *************************/
                   1729: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1730: {
                   1731:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1732:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1733:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1734:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1735:    * returned function value. 
                   1736:   */
1.126     brouard  1737:   int iter; 
                   1738:   double a,b,d,etemp;
1.159     brouard  1739:   double fu=0,fv,fw,fx;
1.164     brouard  1740:   double ftemp=0.;
1.126     brouard  1741:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1742:   double e=0.0; 
                   1743:  
                   1744:   a=(ax < cx ? ax : cx); 
                   1745:   b=(ax > cx ? ax : cx); 
                   1746:   x=w=v=bx; 
                   1747:   fw=fv=fx=(*f)(x); 
                   1748:   for (iter=1;iter<=ITMAX;iter++) { 
                   1749:     xm=0.5*(a+b); 
                   1750:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1751:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1752:     printf(".");fflush(stdout);
                   1753:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1754: #ifdef DEBUGBRENT
1.126     brouard  1755:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1756:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1757:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1758: #endif
                   1759:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1760:       *xmin=x; 
                   1761:       return fx; 
                   1762:     } 
                   1763:     ftemp=fu;
                   1764:     if (fabs(e) > tol1) { 
                   1765:       r=(x-w)*(fx-fv); 
                   1766:       q=(x-v)*(fx-fw); 
                   1767:       p=(x-v)*q-(x-w)*r; 
                   1768:       q=2.0*(q-r); 
                   1769:       if (q > 0.0) p = -p; 
                   1770:       q=fabs(q); 
                   1771:       etemp=e; 
                   1772:       e=d; 
                   1773:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1774:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1775:       else { 
1.224     brouard  1776:                                d=p/q; 
                   1777:                                u=x+d; 
                   1778:                                if (u-a < tol2 || b-u < tol2) 
                   1779:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1780:       } 
                   1781:     } else { 
                   1782:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1783:     } 
                   1784:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1785:     fu=(*f)(u); 
                   1786:     if (fu <= fx) { 
                   1787:       if (u >= x) a=x; else b=x; 
                   1788:       SHFT(v,w,x,u) 
1.183     brouard  1789:       SHFT(fv,fw,fx,fu) 
                   1790:     } else { 
                   1791:       if (u < x) a=u; else b=u; 
                   1792:       if (fu <= fw || w == x) { 
1.224     brouard  1793:                                v=w; 
                   1794:                                w=u; 
                   1795:                                fv=fw; 
                   1796:                                fw=fu; 
1.183     brouard  1797:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1798:                                v=u; 
                   1799:                                fv=fu; 
1.183     brouard  1800:       } 
                   1801:     } 
1.126     brouard  1802:   } 
                   1803:   nrerror("Too many iterations in brent"); 
                   1804:   *xmin=x; 
                   1805:   return fx; 
                   1806: } 
                   1807: 
                   1808: /****************** mnbrak ***********************/
                   1809: 
                   1810: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1811:            double (*func)(double)) 
1.183     brouard  1812: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1813: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1814: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1815: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1816:    */
1.126     brouard  1817:   double ulim,u,r,q, dum;
                   1818:   double fu; 
1.187     brouard  1819: 
                   1820:   double scale=10.;
                   1821:   int iterscale=0;
                   1822: 
                   1823:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1824:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1825: 
                   1826: 
                   1827:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1828:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1829:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1830:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1831:   /* } */
                   1832: 
1.126     brouard  1833:   if (*fb > *fa) { 
                   1834:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1835:     SHFT(dum,*fb,*fa,dum) 
                   1836:   } 
1.126     brouard  1837:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1838:   *fc=(*func)(*cx); 
1.183     brouard  1839: #ifdef DEBUG
1.224     brouard  1840:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1841:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1842: #endif
1.224     brouard  1843:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1844:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1845:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1846:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1847:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1848:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1849:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1850:       fu=(*func)(u); 
1.163     brouard  1851: #ifdef DEBUG
                   1852:       /* f(x)=A(x-u)**2+f(u) */
                   1853:       double A, fparabu; 
                   1854:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1855:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1856:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1857:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1858:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1859:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1860:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1861:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1862: #endif 
1.184     brouard  1863: #ifdef MNBRAKORIGINAL
1.183     brouard  1864: #else
1.191     brouard  1865: /*       if (fu > *fc) { */
                   1866: /* #ifdef DEBUG */
                   1867: /*       printf("mnbrak4  fu > fc \n"); */
                   1868: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1869: /* #endif */
                   1870: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1871: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1872: /*     dum=u; /\* Shifting c and u *\/ */
                   1873: /*     u = *cx; */
                   1874: /*     *cx = dum; */
                   1875: /*     dum = fu; */
                   1876: /*     fu = *fc; */
                   1877: /*     *fc =dum; */
                   1878: /*       } else { /\* end *\/ */
                   1879: /* #ifdef DEBUG */
                   1880: /*       printf("mnbrak3  fu < fc \n"); */
                   1881: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1882: /* #endif */
                   1883: /*     dum=u; /\* Shifting c and u *\/ */
                   1884: /*     u = *cx; */
                   1885: /*     *cx = dum; */
                   1886: /*     dum = fu; */
                   1887: /*     fu = *fc; */
                   1888: /*     *fc =dum; */
                   1889: /*       } */
1.224     brouard  1890: #ifdef DEBUGMNBRAK
                   1891:                 double A, fparabu; 
                   1892:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1893:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1894:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1895:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1896: #endif
1.191     brouard  1897:       dum=u; /* Shifting c and u */
                   1898:       u = *cx;
                   1899:       *cx = dum;
                   1900:       dum = fu;
                   1901:       fu = *fc;
                   1902:       *fc =dum;
1.183     brouard  1903: #endif
1.162     brouard  1904:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1905: #ifdef DEBUG
1.224     brouard  1906:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1907:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1908: #endif
1.126     brouard  1909:       fu=(*func)(u); 
                   1910:       if (fu < *fc) { 
1.183     brouard  1911: #ifdef DEBUG
1.224     brouard  1912:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1913:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1914: #endif
                   1915:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1916:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1917: #ifdef DEBUG
                   1918:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1919: #endif
                   1920:       } 
1.162     brouard  1921:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1922: #ifdef DEBUG
1.224     brouard  1923:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1924:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1925: #endif
1.126     brouard  1926:       u=ulim; 
                   1927:       fu=(*func)(u); 
1.183     brouard  1928:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1929: #ifdef DEBUG
1.224     brouard  1930:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1931:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1932: #endif
1.126     brouard  1933:       u=(*cx)+GOLD*(*cx-*bx); 
                   1934:       fu=(*func)(u); 
1.224     brouard  1935: #ifdef DEBUG
                   1936:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1937:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1938: #endif
1.183     brouard  1939:     } /* end tests */
1.126     brouard  1940:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  1941:     SHFT(*fa,*fb,*fc,fu) 
                   1942: #ifdef DEBUG
1.224     brouard  1943:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   1944:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  1945: #endif
                   1946:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  1947: } 
                   1948: 
                   1949: /*************** linmin ************************/
1.162     brouard  1950: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   1951: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   1952: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   1953: the value of func at the returned location p . This is actually all accomplished by calling the
                   1954: routines mnbrak and brent .*/
1.126     brouard  1955: int ncom; 
                   1956: double *pcom,*xicom;
                   1957: double (*nrfunc)(double []); 
                   1958:  
1.224     brouard  1959: #ifdef LINMINORIGINAL
1.126     brouard  1960: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  1961: #else
                   1962: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   1963: #endif
1.126     brouard  1964: { 
                   1965:   double brent(double ax, double bx, double cx, 
                   1966:               double (*f)(double), double tol, double *xmin); 
                   1967:   double f1dim(double x); 
                   1968:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   1969:              double *fc, double (*func)(double)); 
                   1970:   int j; 
                   1971:   double xx,xmin,bx,ax; 
                   1972:   double fx,fb,fa;
1.187     brouard  1973: 
1.203     brouard  1974: #ifdef LINMINORIGINAL
                   1975: #else
                   1976:   double scale=10., axs, xxs; /* Scale added for infinity */
                   1977: #endif
                   1978:   
1.126     brouard  1979:   ncom=n; 
                   1980:   pcom=vector(1,n); 
                   1981:   xicom=vector(1,n); 
                   1982:   nrfunc=func; 
                   1983:   for (j=1;j<=n;j++) { 
                   1984:     pcom[j]=p[j]; 
1.202     brouard  1985:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  1986:   } 
1.187     brouard  1987: 
1.203     brouard  1988: #ifdef LINMINORIGINAL
                   1989:   xx=1.;
                   1990: #else
                   1991:   axs=0.0;
                   1992:   xxs=1.;
                   1993:   do{
                   1994:     xx= xxs;
                   1995: #endif
1.187     brouard  1996:     ax=0.;
                   1997:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   1998:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   1999:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2000:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2001:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2002:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2003:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2004: #ifdef LINMINORIGINAL
                   2005: #else
                   2006:     if (fx != fx){
1.224     brouard  2007:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2008:                        printf("|");
                   2009:                        fprintf(ficlog,"|");
1.203     brouard  2010: #ifdef DEBUGLINMIN
1.224     brouard  2011:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2012: #endif
                   2013:     }
1.224     brouard  2014:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2015: #endif
                   2016:   
1.191     brouard  2017: #ifdef DEBUGLINMIN
                   2018:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2019:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2020: #endif
1.224     brouard  2021: #ifdef LINMINORIGINAL
                   2022: #else
                   2023:        if(fb == fx){ /* Flat function in the direction */
                   2024:                xmin=xx;
                   2025:     *flat=1;
                   2026:        }else{
                   2027:     *flat=0;
                   2028: #endif
                   2029:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2030:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2031:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2032:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2033:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2034:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2035: #ifdef DEBUG
1.224     brouard  2036:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2037:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2038: #endif
                   2039: #ifdef LINMINORIGINAL
                   2040: #else
                   2041:                        }
1.126     brouard  2042: #endif
1.191     brouard  2043: #ifdef DEBUGLINMIN
                   2044:   printf("linmin end ");
1.202     brouard  2045:   fprintf(ficlog,"linmin end ");
1.191     brouard  2046: #endif
1.126     brouard  2047:   for (j=1;j<=n;j++) { 
1.203     brouard  2048: #ifdef LINMINORIGINAL
                   2049:     xi[j] *= xmin; 
                   2050: #else
                   2051: #ifdef DEBUGLINMIN
                   2052:     if(xxs <1.0)
                   2053:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2054: #endif
                   2055:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2056: #ifdef DEBUGLINMIN
                   2057:     if(xxs <1.0)
                   2058:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2059: #endif
                   2060: #endif
1.187     brouard  2061:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2062:   } 
1.191     brouard  2063: #ifdef DEBUGLINMIN
1.203     brouard  2064:   printf("\n");
1.191     brouard  2065:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2066:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2067:   for (j=1;j<=n;j++) { 
1.202     brouard  2068:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2069:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2070:     if(j % ncovmodel == 0){
1.191     brouard  2071:       printf("\n");
1.202     brouard  2072:       fprintf(ficlog,"\n");
                   2073:     }
1.191     brouard  2074:   }
1.203     brouard  2075: #else
1.191     brouard  2076: #endif
1.126     brouard  2077:   free_vector(xicom,1,n); 
                   2078:   free_vector(pcom,1,n); 
                   2079: } 
                   2080: 
                   2081: 
                   2082: /*************** powell ************************/
1.162     brouard  2083: /*
                   2084: Minimization of a function func of n variables. Input consists of an initial starting point
                   2085: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2086: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2087: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2088: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2089: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2090:  */
1.224     brouard  2091: #ifdef LINMINORIGINAL
                   2092: #else
                   2093:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2094:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2095: #endif
1.126     brouard  2096: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2097:            double (*func)(double [])) 
                   2098: { 
1.224     brouard  2099: #ifdef LINMINORIGINAL
                   2100:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2101:              double (*func)(double [])); 
1.224     brouard  2102: #else 
1.241     brouard  2103:  void linmin(double p[], double xi[], int n, double *fret,
                   2104:             double (*func)(double []),int *flat); 
1.224     brouard  2105: #endif
1.239     brouard  2106:  int i,ibig,j,jk,k; 
1.126     brouard  2107:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2108:   double directest;
1.126     brouard  2109:   double fp,fptt;
                   2110:   double *xits;
                   2111:   int niterf, itmp;
1.224     brouard  2112: #ifdef LINMINORIGINAL
                   2113: #else
                   2114: 
                   2115:   flatdir=ivector(1,n); 
                   2116:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2117: #endif
1.126     brouard  2118: 
                   2119:   pt=vector(1,n); 
                   2120:   ptt=vector(1,n); 
                   2121:   xit=vector(1,n); 
                   2122:   xits=vector(1,n); 
                   2123:   *fret=(*func)(p); 
                   2124:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2125:   rcurr_time = time(NULL);  
1.126     brouard  2126:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2127:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2128:     ibig=0; 
                   2129:     del=0.0; 
1.157     brouard  2130:     rlast_time=rcurr_time;
                   2131:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2132:     rcurr_time = time(NULL);  
                   2133:     curr_time = *localtime(&rcurr_time);
                   2134:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2135:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2136: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2137:     for (i=1;i<=n;i++) {
1.126     brouard  2138:       fprintf(ficrespow," %.12lf", p[i]);
                   2139:     }
1.239     brouard  2140:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2141:     printf("\n#model=  1      +     age ");
                   2142:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2143:     if(nagesqr==1){
1.241     brouard  2144:        printf("  + age*age  ");
                   2145:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2146:     }
                   2147:     for(j=1;j <=ncovmodel-2;j++){
                   2148:       if(Typevar[j]==0) {
                   2149:        printf("  +      V%d  ",Tvar[j]);
                   2150:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2151:       }else if(Typevar[j]==1) {
                   2152:        printf("  +    V%d*age ",Tvar[j]);
                   2153:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2154:       }else if(Typevar[j]==2) {
                   2155:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2156:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2157:       }
                   2158:     }
1.126     brouard  2159:     printf("\n");
1.239     brouard  2160: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2161: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2162:     fprintf(ficlog,"\n");
1.239     brouard  2163:     for(i=1,jk=1; i <=nlstate; i++){
                   2164:       for(k=1; k <=(nlstate+ndeath); k++){
                   2165:        if (k != i) {
                   2166:          printf("%d%d ",i,k);
                   2167:          fprintf(ficlog,"%d%d ",i,k);
                   2168:          for(j=1; j <=ncovmodel; j++){
                   2169:            printf("%12.7f ",p[jk]);
                   2170:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2171:            jk++; 
                   2172:          }
                   2173:          printf("\n");
                   2174:          fprintf(ficlog,"\n");
                   2175:        }
                   2176:       }
                   2177:     }
1.241     brouard  2178:     if(*iter <=3 && *iter >1){
1.157     brouard  2179:       tml = *localtime(&rcurr_time);
                   2180:       strcpy(strcurr,asctime(&tml));
                   2181:       rforecast_time=rcurr_time; 
1.126     brouard  2182:       itmp = strlen(strcurr);
                   2183:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2184:        strcurr[itmp-1]='\0';
1.162     brouard  2185:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2186:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2187:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2188:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2189:        forecast_time = *localtime(&rforecast_time);
                   2190:        strcpy(strfor,asctime(&forecast_time));
                   2191:        itmp = strlen(strfor);
                   2192:        if(strfor[itmp-1]=='\n')
                   2193:          strfor[itmp-1]='\0';
                   2194:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2195:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2196:       }
                   2197:     }
1.187     brouard  2198:     for (i=1;i<=n;i++) { /* For each direction i */
                   2199:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2200:       fptt=(*fret); 
                   2201: #ifdef DEBUG
1.203     brouard  2202:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2203:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2204: #endif
1.203     brouard  2205:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2206:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2207: #ifdef LINMINORIGINAL
1.188     brouard  2208:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2209: #else
                   2210:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2211:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2212: #endif
                   2213:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2214:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2215:                                /* because that direction will be replaced unless the gain del is small */
                   2216:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2217:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2218:                                /* with the new direction. */
                   2219:                                del=fabs(fptt-(*fret)); 
                   2220:                                ibig=i; 
1.126     brouard  2221:       } 
                   2222: #ifdef DEBUG
                   2223:       printf("%d %.12e",i,(*fret));
                   2224:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2225:       for (j=1;j<=n;j++) {
1.224     brouard  2226:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2227:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2228:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2229:       }
                   2230:       for(j=1;j<=n;j++) {
1.225     brouard  2231:                                printf(" p(%d)=%.12e",j,p[j]);
                   2232:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2233:       }
                   2234:       printf("\n");
                   2235:       fprintf(ficlog,"\n");
                   2236: #endif
1.187     brouard  2237:     } /* end loop on each direction i */
                   2238:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2239:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2240:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2241:       for(j=1;j<=n;j++) {
1.225     brouard  2242:                                if(flatdir[j] >0){
                   2243:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2244:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2245:                                }
                   2246:                                /* printf("\n"); */
                   2247:                                /* fprintf(ficlog,"\n"); */
                   2248:                        }
1.243     brouard  2249:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2250:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2251:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2252:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2253:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2254:       /* decreased of more than 3.84  */
                   2255:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2256:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2257:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2258:                        
1.188     brouard  2259:       /* Starting the program with initial values given by a former maximization will simply change */
                   2260:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2261:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2262:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2263: #ifdef DEBUG
                   2264:       int k[2],l;
                   2265:       k[0]=1;
                   2266:       k[1]=-1;
                   2267:       printf("Max: %.12e",(*func)(p));
                   2268:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2269:       for (j=1;j<=n;j++) {
                   2270:        printf(" %.12e",p[j]);
                   2271:        fprintf(ficlog," %.12e",p[j]);
                   2272:       }
                   2273:       printf("\n");
                   2274:       fprintf(ficlog,"\n");
                   2275:       for(l=0;l<=1;l++) {
                   2276:        for (j=1;j<=n;j++) {
                   2277:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2278:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2279:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2280:        }
                   2281:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2282:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2283:       }
                   2284: #endif
                   2285: 
1.224     brouard  2286: #ifdef LINMINORIGINAL
                   2287: #else
                   2288:       free_ivector(flatdir,1,n); 
                   2289: #endif
1.126     brouard  2290:       free_vector(xit,1,n); 
                   2291:       free_vector(xits,1,n); 
                   2292:       free_vector(ptt,1,n); 
                   2293:       free_vector(pt,1,n); 
                   2294:       return; 
1.192     brouard  2295:     } /* enough precision */ 
1.240     brouard  2296:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2297:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2298:       ptt[j]=2.0*p[j]-pt[j]; 
                   2299:       xit[j]=p[j]-pt[j]; 
                   2300:       pt[j]=p[j]; 
                   2301:     } 
1.181     brouard  2302:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2303: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2304:                if (*iter <=4) {
1.225     brouard  2305: #else
                   2306: #endif
1.224     brouard  2307: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2308: #else
1.161     brouard  2309:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2310: #endif
1.162     brouard  2311:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2312:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2313:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2314:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2315:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2316:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2317:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2318:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2319:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2320:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2321:       /* mu² and del² are equal when f3=f1 */
                   2322:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2323:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2324:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2325:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2326: #ifdef NRCORIGINAL
                   2327:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2328: #else
                   2329:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2330:       t= t- del*SQR(fp-fptt);
1.183     brouard  2331: #endif
1.202     brouard  2332:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2333: #ifdef DEBUG
1.181     brouard  2334:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2335:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2336:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2337:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2338:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2339:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2340:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2341:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2342: #endif
1.183     brouard  2343: #ifdef POWELLORIGINAL
                   2344:       if (t < 0.0) { /* Then we use it for new direction */
                   2345: #else
1.182     brouard  2346:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2347:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2348:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2349:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2350:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2351:       } 
1.181     brouard  2352:       if (directest < 0.0) { /* Then we use it for new direction */
                   2353: #endif
1.191     brouard  2354: #ifdef DEBUGLINMIN
1.234     brouard  2355:        printf("Before linmin in direction P%d-P0\n",n);
                   2356:        for (j=1;j<=n;j++) {
                   2357:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2358:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2359:          if(j % ncovmodel == 0){
                   2360:            printf("\n");
                   2361:            fprintf(ficlog,"\n");
                   2362:          }
                   2363:        }
1.224     brouard  2364: #endif
                   2365: #ifdef LINMINORIGINAL
1.234     brouard  2366:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2367: #else
1.234     brouard  2368:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2369:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2370: #endif
1.234     brouard  2371:        
1.191     brouard  2372: #ifdef DEBUGLINMIN
1.234     brouard  2373:        for (j=1;j<=n;j++) { 
                   2374:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2375:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2376:          if(j % ncovmodel == 0){
                   2377:            printf("\n");
                   2378:            fprintf(ficlog,"\n");
                   2379:          }
                   2380:        }
1.224     brouard  2381: #endif
1.234     brouard  2382:        for (j=1;j<=n;j++) { 
                   2383:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2384:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2385:        }
1.224     brouard  2386: #ifdef LINMINORIGINAL
                   2387: #else
1.234     brouard  2388:        for (j=1, flatd=0;j<=n;j++) {
                   2389:          if(flatdir[j]>0)
                   2390:            flatd++;
                   2391:        }
                   2392:        if(flatd >0){
                   2393:          printf("%d flat directions\n",flatd);
                   2394:          fprintf(ficlog,"%d flat directions\n",flatd);
                   2395:          for (j=1;j<=n;j++) { 
                   2396:            if(flatdir[j]>0){
                   2397:              printf("%d ",j);
                   2398:              fprintf(ficlog,"%d ",j);
                   2399:            }
                   2400:          }
                   2401:          printf("\n");
                   2402:          fprintf(ficlog,"\n");
                   2403:        }
1.191     brouard  2404: #endif
1.234     brouard  2405:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2406:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2407:        
1.126     brouard  2408: #ifdef DEBUG
1.234     brouard  2409:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2410:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2411:        for(j=1;j<=n;j++){
                   2412:          printf(" %lf",xit[j]);
                   2413:          fprintf(ficlog," %lf",xit[j]);
                   2414:        }
                   2415:        printf("\n");
                   2416:        fprintf(ficlog,"\n");
1.126     brouard  2417: #endif
1.192     brouard  2418:       } /* end of t or directest negative */
1.224     brouard  2419: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2420: #else
1.234     brouard  2421:       } /* end if (fptt < fp)  */
1.192     brouard  2422: #endif
1.225     brouard  2423: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2424:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2425: #else
1.224     brouard  2426: #endif
1.234     brouard  2427:                } /* loop iteration */ 
1.126     brouard  2428: } 
1.234     brouard  2429:   
1.126     brouard  2430: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2431:   
1.235     brouard  2432:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2433:   {
1.235     brouard  2434:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2435:        (and selected quantitative values in nres)
                   2436:        by left multiplying the unit
1.234     brouard  2437:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2438:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2439:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2440:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2441:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2442:   /* Initial matrix pimij */
                   2443:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2444:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2445:   /*  0,                   0                  , 1} */
                   2446:   /*
                   2447:    * and after some iteration: */
                   2448:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2449:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2450:   /*  0,                   0                  , 1} */
                   2451:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2452:   /* {0.51571254859325999, 0.4842874514067399, */
                   2453:   /*  0.51326036147820708, 0.48673963852179264} */
                   2454:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2455:     
1.126     brouard  2456:   int i, ii,j,k;
1.209     brouard  2457:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2458:   /* double **matprod2(); */ /* test */
1.218     brouard  2459:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2460:   double **newm;
1.209     brouard  2461:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2462:   int ncvloop=0;
1.169     brouard  2463:   
1.209     brouard  2464:   min=vector(1,nlstate);
                   2465:   max=vector(1,nlstate);
                   2466:   meandiff=vector(1,nlstate);
                   2467: 
1.218     brouard  2468:        /* Starting with matrix unity */
1.126     brouard  2469:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2470:     for (j=1;j<=nlstate+ndeath;j++){
                   2471:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2472:     }
1.169     brouard  2473:   
                   2474:   cov[1]=1.;
                   2475:   
                   2476:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2477:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2478:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2479:     ncvloop++;
1.126     brouard  2480:     newm=savm;
                   2481:     /* Covariates have to be included here again */
1.138     brouard  2482:     cov[2]=agefin;
1.187     brouard  2483:     if(nagesqr==1)
                   2484:       cov[3]= agefin*agefin;;
1.234     brouard  2485:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2486:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2487:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2488:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2489:     }
                   2490:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2491:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2492:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2493:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2494:     }
1.237     brouard  2495:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2496:       if(Dummy[Tvar[Tage[k]]]){
                   2497:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2498:       } else{
1.235     brouard  2499:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2500:       }
1.235     brouard  2501:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2502:     }
1.237     brouard  2503:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2504:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2505:       if(Dummy[Tvard[k][1]==0]){
                   2506:        if(Dummy[Tvard[k][2]==0]){
                   2507:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2508:        }else{
                   2509:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2510:        }
                   2511:       }else{
                   2512:        if(Dummy[Tvard[k][2]==0]){
                   2513:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2514:        }else{
                   2515:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2516:        }
                   2517:       }
1.234     brouard  2518:     }
1.138     brouard  2519:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2520:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2521:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2522:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2523:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2524:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2525:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2526:     
1.126     brouard  2527:     savm=oldm;
                   2528:     oldm=newm;
1.209     brouard  2529: 
                   2530:     for(j=1; j<=nlstate; j++){
                   2531:       max[j]=0.;
                   2532:       min[j]=1.;
                   2533:     }
                   2534:     for(i=1;i<=nlstate;i++){
                   2535:       sumnew=0;
                   2536:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2537:       for(j=1; j<=nlstate; j++){ 
                   2538:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2539:        max[j]=FMAX(max[j],prlim[i][j]);
                   2540:        min[j]=FMIN(min[j],prlim[i][j]);
                   2541:       }
                   2542:     }
                   2543: 
1.126     brouard  2544:     maxmax=0.;
1.209     brouard  2545:     for(j=1; j<=nlstate; j++){
                   2546:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2547:       maxmax=FMAX(maxmax,meandiff[j]);
                   2548:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2549:     } /* j loop */
1.203     brouard  2550:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2551:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2552:     if(maxmax < ftolpl){
1.209     brouard  2553:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2554:       free_vector(min,1,nlstate);
                   2555:       free_vector(max,1,nlstate);
                   2556:       free_vector(meandiff,1,nlstate);
1.126     brouard  2557:       return prlim;
                   2558:     }
1.169     brouard  2559:   } /* age loop */
1.208     brouard  2560:     /* After some age loop it doesn't converge */
1.209     brouard  2561:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2562: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2563:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2564:   free_vector(min,1,nlstate);
                   2565:   free_vector(max,1,nlstate);
                   2566:   free_vector(meandiff,1,nlstate);
1.208     brouard  2567:   
1.169     brouard  2568:   return prlim; /* should not reach here */
1.126     brouard  2569: }
                   2570: 
1.217     brouard  2571: 
                   2572:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2573: 
1.218     brouard  2574:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2575:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2576:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2577: {
1.218     brouard  2578:   /* Computes the prevalence limit in each live state at age x and covariate ij by left multiplying the unit
1.217     brouard  2579:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2580:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2581:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2582:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2583:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2584:   /* Initial matrix pimij */
                   2585:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2586:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2587:   /*  0,                   0                  , 1} */
                   2588:   /*
                   2589:    * and after some iteration: */
                   2590:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2591:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2592:   /*  0,                   0                  , 1} */
                   2593:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2594:   /* {0.51571254859325999, 0.4842874514067399, */
                   2595:   /*  0.51326036147820708, 0.48673963852179264} */
                   2596:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2597: 
                   2598:   int i, ii,j,k;
1.247     brouard  2599:   int first=0;
1.217     brouard  2600:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2601:   /* double **matprod2(); */ /* test */
                   2602:   double **out, cov[NCOVMAX+1], **bmij();
                   2603:   double **newm;
1.218     brouard  2604:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2605:   double        **oldm, **savm;  /* for use */
                   2606: 
1.217     brouard  2607:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2608:   int ncvloop=0;
                   2609:   
                   2610:   min=vector(1,nlstate);
                   2611:   max=vector(1,nlstate);
                   2612:   meandiff=vector(1,nlstate);
                   2613: 
1.218     brouard  2614:        dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2615:        oldm=oldms; savm=savms;
                   2616: 
                   2617:        /* Starting with matrix unity */
                   2618:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   2619:                for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2620:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2621:     }
                   2622:   
                   2623:   cov[1]=1.;
                   2624:   
                   2625:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2626:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2627:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2628:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2629:     ncvloop++;
1.218     brouard  2630:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2631:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2632:     /* Covariates have to be included here again */
                   2633:     cov[2]=agefin;
                   2634:     if(nagesqr==1)
                   2635:       cov[3]= agefin*agefin;;
1.242     brouard  2636:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2637:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2638:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   2639:       /* printf("bprevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   2640:     }
                   2641:     /* for (k=1; k<=cptcovn;k++) { */
                   2642:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2643:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2644:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2645:     /* } */
                   2646:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2647:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2648:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2649:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2650:     }
                   2651:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2652:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2653:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2654:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2655:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2656:       if(Dummy[Tvar[Tage[k]]]){
                   2657:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2658:       } else{
                   2659:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2660:       }
                   2661:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2662:     }
                   2663:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2664:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2665:       if(Dummy[Tvard[k][1]==0]){
                   2666:        if(Dummy[Tvard[k][2]==0]){
                   2667:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2668:        }else{
                   2669:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2670:        }
                   2671:       }else{
                   2672:        if(Dummy[Tvard[k][2]==0]){
                   2673:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2674:        }else{
                   2675:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2676:        }
                   2677:       }
1.217     brouard  2678:     }
                   2679:     
                   2680:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2681:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2682:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2683:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2684:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2685:                /* ij should be linked to the correct index of cov */
                   2686:                /* age and covariate values ij are in 'cov', but we need to pass
                   2687:                 * ij for the observed prevalence at age and status and covariate
                   2688:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2689:                 */
                   2690:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2691:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2692:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.217     brouard  2693:     savm=oldm;
                   2694:     oldm=newm;
                   2695:     for(j=1; j<=nlstate; j++){
                   2696:       max[j]=0.;
                   2697:       min[j]=1.;
                   2698:     }
                   2699:     for(j=1; j<=nlstate; j++){ 
                   2700:       for(i=1;i<=nlstate;i++){
1.234     brouard  2701:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2702:        bprlim[i][j]= newm[i][j];
                   2703:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2704:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2705:       }
                   2706:     }
1.218     brouard  2707:                
1.217     brouard  2708:     maxmax=0.;
                   2709:     for(i=1; i<=nlstate; i++){
                   2710:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2711:       maxmax=FMAX(maxmax,meandiff[i]);
                   2712:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
                   2713:     } /* j loop */
                   2714:     *ncvyear= -( (int)age- (int)agefin);
1.218     brouard  2715:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear);*/
1.217     brouard  2716:     if(maxmax < ftolpl){
1.220     brouard  2717:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2718:       free_vector(min,1,nlstate);
                   2719:       free_vector(max,1,nlstate);
                   2720:       free_vector(meandiff,1,nlstate);
                   2721:       return bprlim;
                   2722:     }
                   2723:   } /* age loop */
                   2724:     /* After some age loop it doesn't converge */
1.247     brouard  2725:   if(first){
                   2726:     first=1;
                   2727:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2728: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2729:   }
                   2730:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2731: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2732:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2733:   free_vector(min,1,nlstate);
                   2734:   free_vector(max,1,nlstate);
                   2735:   free_vector(meandiff,1,nlstate);
                   2736:   
                   2737:   return bprlim; /* should not reach here */
                   2738: }
                   2739: 
1.126     brouard  2740: /*************** transition probabilities ***************/ 
                   2741: 
                   2742: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2743: {
1.138     brouard  2744:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2745:      computes the probability to be observed in state j being in state i by appying the
                   2746:      model to the ncovmodel covariates (including constant and age).
                   2747:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2748:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2749:      ncth covariate in the global vector x is given by the formula:
                   2750:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2751:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2752:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2753:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2754:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2755:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2756:   */
                   2757:   double s1, lnpijopii;
1.126     brouard  2758:   /*double t34;*/
1.164     brouard  2759:   int i,j, nc, ii, jj;
1.126     brouard  2760: 
1.223     brouard  2761:   for(i=1; i<= nlstate; i++){
                   2762:     for(j=1; j<i;j++){
                   2763:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2764:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2765:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2766:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2767:       }
                   2768:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2769:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2770:     }
                   2771:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2772:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2773:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2774:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2775:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2776:       }
                   2777:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2778:     }
                   2779:   }
1.218     brouard  2780:   
1.223     brouard  2781:   for(i=1; i<= nlstate; i++){
                   2782:     s1=0;
                   2783:     for(j=1; j<i; j++){
                   2784:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2785:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2786:     }
                   2787:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2788:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2789:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2790:     }
                   2791:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2792:     ps[i][i]=1./(s1+1.);
                   2793:     /* Computing other pijs */
                   2794:     for(j=1; j<i; j++)
                   2795:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2796:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2797:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2798:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2799:   } /* end i */
1.218     brouard  2800:   
1.223     brouard  2801:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2802:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2803:       ps[ii][jj]=0;
                   2804:       ps[ii][ii]=1;
                   2805:     }
                   2806:   }
1.218     brouard  2807:   
                   2808:   
1.223     brouard  2809:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2810:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2811:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2812:   /*   } */
                   2813:   /*   printf("\n "); */
                   2814:   /* } */
                   2815:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2816:   /*
                   2817:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2818:                goto end;*/
1.223     brouard  2819:   return ps;
1.126     brouard  2820: }
                   2821: 
1.218     brouard  2822: /*************** backward transition probabilities ***************/ 
                   2823: 
                   2824:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2825: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2826:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2827: {
1.222     brouard  2828:   /* Computes the backward probability at age agefin and covariate ij
                   2829:    * and returns in **ps as well as **bmij.
                   2830:    */
1.218     brouard  2831:   int i, ii, j,k;
1.222     brouard  2832:   
                   2833:   double **out, **pmij();
                   2834:   double sumnew=0.;
1.218     brouard  2835:   double agefin;
1.222     brouard  2836:   
                   2837:   double **dnewm, **dsavm, **doldm;
                   2838:   double **bbmij;
                   2839:   
1.218     brouard  2840:   doldm=ddoldms; /* global pointers */
1.222     brouard  2841:   dnewm=ddnewms;
                   2842:   dsavm=ddsavms;
                   2843:   
                   2844:   agefin=cov[2];
                   2845:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
                   2846:      the observed prevalence (with this covariate ij) */
                   2847:   dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate);
                   2848:   /* We do have the matrix Px in savm  and we need pij */
                   2849:   for (j=1;j<=nlstate+ndeath;j++){
                   2850:     sumnew=0.; /* w1 p11 + w2 p21 only on live states */
                   2851:     for (ii=1;ii<=nlstate;ii++){
                   2852:       sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij];
                   2853:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
                   2854:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2855:       if(sumnew >= 1.e-10){
                   2856:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
                   2857:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2858:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
                   2859:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2860:        /* }else */
                   2861:        doldm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2862:       }else{
1.242     brouard  2863:        ;
                   2864:        /* printf("ii=%d, i=%d, doldm=%lf dsavm=%lf, probs=%lf, sumnew=%lf,agefin=%d\n",ii,j,doldm[ii][j],dsavm[ii][j],prevacurrent[(int)agefin][ii][ij],sumnew, (int)agefin); */
1.222     brouard  2865:       }
                   2866:     } /*End ii */
                   2867:   } /* End j, At the end doldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2868:   /* left Product of this diag matrix by dsavm=Px (newm=dsavm*doldm) */
                   2869:   bbmij=matprod2(dnewm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, doldm); /* Bug Valgrind */
                   2870:   /* dsavm=doldm; /\* dsavm is now diag [1/(w_1p1i+w_2 p2i)] but can be overwritten*\/ */
                   2871:   /* doldm=dnewm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2872:   /* dnewm=dsavm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2873:   /* left Product of this matrix by diag matrix of prevalences (savm) */
                   2874:   for (j=1;j<=nlstate+ndeath;j++){
                   2875:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2876:       dsavm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij] : 0.0);
                   2877:     }
                   2878:   } /* End j, At the end oldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2879:   ps=matprod2(doldm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dnewm); /* Bug Valgrind */
                   2880:   /* newm or out is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
                   2881:   /* end bmij */
                   2882:   return ps; 
1.218     brouard  2883: }
1.217     brouard  2884: /*************** transition probabilities ***************/ 
                   2885: 
1.218     brouard  2886: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2887: {
                   2888:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2889:      computes the probability to be observed in state j being in state i by appying the
                   2890:      model to the ncovmodel covariates (including constant and age).
                   2891:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2892:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2893:      ncth covariate in the global vector x is given by the formula:
                   2894:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2895:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2896:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2897:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2898:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2899:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2900:   */
                   2901:   double s1, lnpijopii;
                   2902:   /*double t34;*/
                   2903:   int i,j, nc, ii, jj;
                   2904: 
1.234     brouard  2905:   for(i=1; i<= nlstate; i++){
                   2906:     for(j=1; j<i;j++){
                   2907:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2908:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2909:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2910:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2911:       }
                   2912:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2913:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2914:     }
                   2915:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2916:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2917:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2918:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2919:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2920:       }
                   2921:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2922:     }
                   2923:   }
                   2924:   
                   2925:   for(i=1; i<= nlstate; i++){
                   2926:     s1=0;
                   2927:     for(j=1; j<i; j++){
                   2928:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2929:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2930:     }
                   2931:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2932:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2933:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2934:     }
                   2935:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2936:     ps[i][i]=1./(s1+1.);
                   2937:     /* Computing other pijs */
                   2938:     for(j=1; j<i; j++)
                   2939:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2940:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2941:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2942:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2943:   } /* end i */
                   2944:   
                   2945:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2946:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2947:       ps[ii][jj]=0;
                   2948:       ps[ii][ii]=1;
                   2949:     }
                   2950:   }
                   2951:   /* Added for backcast */ /* Transposed matrix too */
                   2952:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2953:     s1=0.;
                   2954:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   2955:       s1+=ps[ii][jj];
                   2956:     }
                   2957:     for(ii=1; ii<= nlstate; ii++){
                   2958:       ps[ii][jj]=ps[ii][jj]/s1;
                   2959:     }
                   2960:   }
                   2961:   /* Transposition */
                   2962:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2963:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   2964:       s1=ps[ii][jj];
                   2965:       ps[ii][jj]=ps[jj][ii];
                   2966:       ps[jj][ii]=s1;
                   2967:     }
                   2968:   }
                   2969:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2970:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2971:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2972:   /*   } */
                   2973:   /*   printf("\n "); */
                   2974:   /* } */
                   2975:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2976:   /*
                   2977:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   2978:     goto end;*/
                   2979:   return ps;
1.217     brouard  2980: }
                   2981: 
                   2982: 
1.126     brouard  2983: /**************** Product of 2 matrices ******************/
                   2984: 
1.145     brouard  2985: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  2986: {
                   2987:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   2988:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   2989:   /* in, b, out are matrice of pointers which should have been initialized 
                   2990:      before: only the contents of out is modified. The function returns
                   2991:      a pointer to pointers identical to out */
1.145     brouard  2992:   int i, j, k;
1.126     brouard  2993:   for(i=nrl; i<= nrh; i++)
1.145     brouard  2994:     for(k=ncolol; k<=ncoloh; k++){
                   2995:       out[i][k]=0.;
                   2996:       for(j=ncl; j<=nch; j++)
                   2997:        out[i][k] +=in[i][j]*b[j][k];
                   2998:     }
1.126     brouard  2999:   return out;
                   3000: }
                   3001: 
                   3002: 
                   3003: /************* Higher Matrix Product ***************/
                   3004: 
1.235     brouard  3005: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3006: {
1.218     brouard  3007:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3008:      'nhstepm*hstepm*stepm' months (i.e. until
                   3009:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3010:      nhstepm*hstepm matrices. 
                   3011:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3012:      (typically every 2 years instead of every month which is too big 
                   3013:      for the memory).
                   3014:      Model is determined by parameters x and covariates have to be 
                   3015:      included manually here. 
                   3016: 
                   3017:      */
                   3018: 
                   3019:   int i, j, d, h, k;
1.131     brouard  3020:   double **out, cov[NCOVMAX+1];
1.126     brouard  3021:   double **newm;
1.187     brouard  3022:   double agexact;
1.214     brouard  3023:   double agebegin, ageend;
1.126     brouard  3024: 
                   3025:   /* Hstepm could be zero and should return the unit matrix */
                   3026:   for (i=1;i<=nlstate+ndeath;i++)
                   3027:     for (j=1;j<=nlstate+ndeath;j++){
                   3028:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3029:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3030:     }
                   3031:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3032:   for(h=1; h <=nhstepm; h++){
                   3033:     for(d=1; d <=hstepm; d++){
                   3034:       newm=savm;
                   3035:       /* Covariates have to be included here again */
                   3036:       cov[1]=1.;
1.214     brouard  3037:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3038:       cov[2]=agexact;
                   3039:       if(nagesqr==1)
1.227     brouard  3040:        cov[3]= agexact*agexact;
1.235     brouard  3041:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3042:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3043:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3044:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3045:       }
                   3046:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3047:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3048:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3049:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3050:       }
                   3051:       for (k=1; k<=cptcovage;k++){
                   3052:        if(Dummy[Tvar[Tage[k]]]){
                   3053:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3054:        } else{
                   3055:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3056:        }
                   3057:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3058:       }
                   3059:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3060:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3061:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3062:       }
                   3063:       /* for (k=1; k<=cptcovn;k++)  */
                   3064:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3065:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3066:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3067:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3068:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3069:       
                   3070:       
1.126     brouard  3071:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3072:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3073:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3074:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3075:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3076:       /* if((int)age == 70){ */
                   3077:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3078:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3079:       /*         printf("%d pmmij ",i); */
                   3080:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3081:       /*           printf("%f ",pmmij[i][j]); */
                   3082:       /*         } */
                   3083:       /*         printf(" oldm "); */
                   3084:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3085:       /*           printf("%f ",oldm[i][j]); */
                   3086:       /*         } */
                   3087:       /*         printf("\n"); */
                   3088:       /*       } */
                   3089:       /* } */
1.126     brouard  3090:       savm=oldm;
                   3091:       oldm=newm;
                   3092:     }
                   3093:     for(i=1; i<=nlstate+ndeath; i++)
                   3094:       for(j=1;j<=nlstate+ndeath;j++) {
1.218     brouard  3095:                                po[i][j][h]=newm[i][j];
                   3096:                                /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3097:       }
1.128     brouard  3098:     /*printf("h=%d ",h);*/
1.126     brouard  3099:   } /* end h */
1.218     brouard  3100:        /*     printf("\n H=%d \n",h); */
1.126     brouard  3101:   return po;
                   3102: }
                   3103: 
1.217     brouard  3104: /************* Higher Back Matrix Product ***************/
1.218     brouard  3105: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.222     brouard  3106: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij )
1.217     brouard  3107: {
1.218     brouard  3108:   /* Computes the transition matrix starting at age 'age' over
1.217     brouard  3109:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3110:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3111:      nhstepm*hstepm matrices.
                   3112:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3113:      (typically every 2 years instead of every month which is too big
1.217     brouard  3114:      for the memory).
1.218     brouard  3115:      Model is determined by parameters x and covariates have to be
                   3116:      included manually here.
1.217     brouard  3117: 
1.222     brouard  3118:   */
1.217     brouard  3119: 
                   3120:   int i, j, d, h, k;
                   3121:   double **out, cov[NCOVMAX+1];
                   3122:   double **newm;
                   3123:   double agexact;
                   3124:   double agebegin, ageend;
1.222     brouard  3125:   double **oldm, **savm;
1.217     brouard  3126: 
1.222     brouard  3127:   oldm=oldms;savm=savms;
1.217     brouard  3128:   /* Hstepm could be zero and should return the unit matrix */
                   3129:   for (i=1;i<=nlstate+ndeath;i++)
                   3130:     for (j=1;j<=nlstate+ndeath;j++){
                   3131:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3132:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3133:     }
                   3134:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3135:   for(h=1; h <=nhstepm; h++){
                   3136:     for(d=1; d <=hstepm; d++){
                   3137:       newm=savm;
                   3138:       /* Covariates have to be included here again */
                   3139:       cov[1]=1.;
                   3140:       agexact=age-((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
                   3141:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3142:       cov[2]=agexact;
                   3143:       if(nagesqr==1)
1.222     brouard  3144:        cov[3]= agexact*agexact;
1.218     brouard  3145:       for (k=1; k<=cptcovn;k++)
1.222     brouard  3146:        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   3147:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.217     brouard  3148:       for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
1.222     brouard  3149:        /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   3150:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3151:       /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
1.217     brouard  3152:       for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
1.222     brouard  3153:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3154:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
1.218     brouard  3155:                        
                   3156:                        
1.217     brouard  3157:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3158:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3159:       /* Careful transposed matrix */
1.222     brouard  3160:       /* age is in cov[2] */
1.218     brouard  3161:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3162:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3163:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3164:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3165:       /* if((int)age == 70){ */
                   3166:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3167:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3168:       /*         printf("%d pmmij ",i); */
                   3169:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3170:       /*           printf("%f ",pmmij[i][j]); */
                   3171:       /*         } */
                   3172:       /*         printf(" oldm "); */
                   3173:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3174:       /*           printf("%f ",oldm[i][j]); */
                   3175:       /*         } */
                   3176:       /*         printf("\n"); */
                   3177:       /*       } */
                   3178:       /* } */
                   3179:       savm=oldm;
                   3180:       oldm=newm;
                   3181:     }
                   3182:     for(i=1; i<=nlstate+ndeath; i++)
                   3183:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3184:        po[i][j][h]=newm[i][j];
                   3185:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.217     brouard  3186:       }
                   3187:     /*printf("h=%d ",h);*/
                   3188:   } /* end h */
1.222     brouard  3189:   /*     printf("\n H=%d \n",h); */
1.217     brouard  3190:   return po;
                   3191: }
                   3192: 
                   3193: 
1.162     brouard  3194: #ifdef NLOPT
                   3195:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3196:   double fret;
                   3197:   double *xt;
                   3198:   int j;
                   3199:   myfunc_data *d2 = (myfunc_data *) pd;
                   3200: /* xt = (p1-1); */
                   3201:   xt=vector(1,n); 
                   3202:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3203: 
                   3204:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3205:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3206:   printf("Function = %.12lf ",fret);
                   3207:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3208:   printf("\n");
                   3209:  free_vector(xt,1,n);
                   3210:   return fret;
                   3211: }
                   3212: #endif
1.126     brouard  3213: 
                   3214: /*************** log-likelihood *************/
                   3215: double func( double *x)
                   3216: {
1.226     brouard  3217:   int i, ii, j, k, mi, d, kk;
                   3218:   int ioffset=0;
                   3219:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3220:   double **out;
                   3221:   double lli; /* Individual log likelihood */
                   3222:   int s1, s2;
1.228     brouard  3223:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3224:   double bbh, survp;
                   3225:   long ipmx;
                   3226:   double agexact;
                   3227:   /*extern weight */
                   3228:   /* We are differentiating ll according to initial status */
                   3229:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3230:   /*for(i=1;i<imx;i++) 
                   3231:     printf(" %d\n",s[4][i]);
                   3232:   */
1.162     brouard  3233: 
1.226     brouard  3234:   ++countcallfunc;
1.162     brouard  3235: 
1.226     brouard  3236:   cov[1]=1.;
1.126     brouard  3237: 
1.226     brouard  3238:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3239:   ioffset=0;
1.226     brouard  3240:   if(mle==1){
                   3241:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3242:       /* Computes the values of the ncovmodel covariates of the model
                   3243:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3244:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3245:         to be observed in j being in i according to the model.
                   3246:       */
1.243     brouard  3247:       ioffset=2+nagesqr ;
1.233     brouard  3248:    /* Fixed */
1.234     brouard  3249:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3250:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3251:       }
1.226     brouard  3252:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3253:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3254:         has been calculated etc */
                   3255:       /* For an individual i, wav[i] gives the number of effective waves */
                   3256:       /* We compute the contribution to Likelihood of each effective transition
                   3257:         mw[mi][i] is real wave of the mi th effectve wave */
                   3258:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3259:         s2=s[mw[mi+1][i]][i];
                   3260:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3261:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3262:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3263:       */
                   3264:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3265:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3266:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3267:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3268:        }
                   3269:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3270:          for (j=1;j<=nlstate+ndeath;j++){
                   3271:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3272:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3273:          }
                   3274:        for(d=0; d<dh[mi][i]; d++){
                   3275:          newm=savm;
                   3276:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3277:          cov[2]=agexact;
                   3278:          if(nagesqr==1)
                   3279:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3280:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3281:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3282:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3283:          else
                   3284:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3285:          }
                   3286:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3287:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3288:          savm=oldm;
                   3289:          oldm=newm;
                   3290:        } /* end mult */
                   3291:        
                   3292:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3293:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3294:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3295:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3296:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3297:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3298:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3299:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3300:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3301:                                 * -stepm/2 to stepm/2 .
                   3302:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3303:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3304:                                 */
1.234     brouard  3305:        s1=s[mw[mi][i]][i];
                   3306:        s2=s[mw[mi+1][i]][i];
                   3307:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3308:        /* bias bh is positive if real duration
                   3309:         * is higher than the multiple of stepm and negative otherwise.
                   3310:         */
                   3311:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3312:        if( s2 > nlstate){ 
                   3313:          /* i.e. if s2 is a death state and if the date of death is known 
                   3314:             then the contribution to the likelihood is the probability to 
                   3315:             die between last step unit time and current  step unit time, 
                   3316:             which is also equal to probability to die before dh 
                   3317:             minus probability to die before dh-stepm . 
                   3318:             In version up to 0.92 likelihood was computed
                   3319:             as if date of death was unknown. Death was treated as any other
                   3320:             health state: the date of the interview describes the actual state
                   3321:             and not the date of a change in health state. The former idea was
                   3322:             to consider that at each interview the state was recorded
                   3323:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3324:             introduced the exact date of death then we should have modified
                   3325:             the contribution of an exact death to the likelihood. This new
                   3326:             contribution is smaller and very dependent of the step unit
                   3327:             stepm. It is no more the probability to die between last interview
                   3328:             and month of death but the probability to survive from last
                   3329:             interview up to one month before death multiplied by the
                   3330:             probability to die within a month. Thanks to Chris
                   3331:             Jackson for correcting this bug.  Former versions increased
                   3332:             mortality artificially. The bad side is that we add another loop
                   3333:             which slows down the processing. The difference can be up to 10%
                   3334:             lower mortality.
                   3335:          */
                   3336:          /* If, at the beginning of the maximization mostly, the
                   3337:             cumulative probability or probability to be dead is
                   3338:             constant (ie = 1) over time d, the difference is equal to
                   3339:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3340:             s1 at precedent wave, to be dead a month before current
                   3341:             wave is equal to probability, being at state s1 at
                   3342:             precedent wave, to be dead at mont of the current
                   3343:             wave. Then the observed probability (that this person died)
                   3344:             is null according to current estimated parameter. In fact,
                   3345:             it should be very low but not zero otherwise the log go to
                   3346:             infinity.
                   3347:          */
1.183     brouard  3348: /* #ifdef INFINITYORIGINAL */
                   3349: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3350: /* #else */
                   3351: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3352: /*         lli=log(mytinydouble); */
                   3353: /*       else */
                   3354: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3355: /* #endif */
1.226     brouard  3356:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3357:          
1.226     brouard  3358:        } else if  ( s2==-1 ) { /* alive */
                   3359:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3360:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3361:          /*survp += out[s1][j]; */
                   3362:          lli= log(survp);
                   3363:        }
                   3364:        else if  (s2==-4) { 
                   3365:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3366:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3367:          lli= log(survp); 
                   3368:        } 
                   3369:        else if  (s2==-5) { 
                   3370:          for (j=1,survp=0. ; j<=2; j++)  
                   3371:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3372:          lli= log(survp); 
                   3373:        } 
                   3374:        else{
                   3375:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3376:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3377:        } 
                   3378:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3379:        /*if(lli ==000.0)*/
                   3380:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3381:        ipmx +=1;
                   3382:        sw += weight[i];
                   3383:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3384:        /* if (lli < log(mytinydouble)){ */
                   3385:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3386:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3387:        /* } */
                   3388:       } /* end of wave */
                   3389:     } /* end of individual */
                   3390:   }  else if(mle==2){
                   3391:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3392:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3393:       for(mi=1; mi<= wav[i]-1; mi++){
                   3394:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3395:          for (j=1;j<=nlstate+ndeath;j++){
                   3396:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3397:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3398:          }
                   3399:        for(d=0; d<=dh[mi][i]; d++){
                   3400:          newm=savm;
                   3401:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3402:          cov[2]=agexact;
                   3403:          if(nagesqr==1)
                   3404:            cov[3]= agexact*agexact;
                   3405:          for (kk=1; kk<=cptcovage;kk++) {
                   3406:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3407:          }
                   3408:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3409:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3410:          savm=oldm;
                   3411:          oldm=newm;
                   3412:        } /* end mult */
                   3413:       
                   3414:        s1=s[mw[mi][i]][i];
                   3415:        s2=s[mw[mi+1][i]][i];
                   3416:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3417:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3418:        ipmx +=1;
                   3419:        sw += weight[i];
                   3420:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3421:       } /* end of wave */
                   3422:     } /* end of individual */
                   3423:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3424:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3425:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3426:       for(mi=1; mi<= wav[i]-1; mi++){
                   3427:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3428:          for (j=1;j<=nlstate+ndeath;j++){
                   3429:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3430:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3431:          }
                   3432:        for(d=0; d<dh[mi][i]; d++){
                   3433:          newm=savm;
                   3434:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3435:          cov[2]=agexact;
                   3436:          if(nagesqr==1)
                   3437:            cov[3]= agexact*agexact;
                   3438:          for (kk=1; kk<=cptcovage;kk++) {
                   3439:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3440:          }
                   3441:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3442:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3443:          savm=oldm;
                   3444:          oldm=newm;
                   3445:        } /* end mult */
                   3446:       
                   3447:        s1=s[mw[mi][i]][i];
                   3448:        s2=s[mw[mi+1][i]][i];
                   3449:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3450:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3451:        ipmx +=1;
                   3452:        sw += weight[i];
                   3453:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3454:       } /* end of wave */
                   3455:     } /* end of individual */
                   3456:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3457:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3458:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3459:       for(mi=1; mi<= wav[i]-1; mi++){
                   3460:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3461:          for (j=1;j<=nlstate+ndeath;j++){
                   3462:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3463:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3464:          }
                   3465:        for(d=0; d<dh[mi][i]; d++){
                   3466:          newm=savm;
                   3467:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3468:          cov[2]=agexact;
                   3469:          if(nagesqr==1)
                   3470:            cov[3]= agexact*agexact;
                   3471:          for (kk=1; kk<=cptcovage;kk++) {
                   3472:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3473:          }
1.126     brouard  3474:        
1.226     brouard  3475:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3476:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3477:          savm=oldm;
                   3478:          oldm=newm;
                   3479:        } /* end mult */
                   3480:       
                   3481:        s1=s[mw[mi][i]][i];
                   3482:        s2=s[mw[mi+1][i]][i];
                   3483:        if( s2 > nlstate){ 
                   3484:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3485:        } else if  ( s2==-1 ) { /* alive */
                   3486:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3487:            survp += out[s1][j];
                   3488:          lli= log(survp);
                   3489:        }else{
                   3490:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3491:        }
                   3492:        ipmx +=1;
                   3493:        sw += weight[i];
                   3494:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3495: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3496:       } /* end of wave */
                   3497:     } /* end of individual */
                   3498:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3499:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3500:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3501:       for(mi=1; mi<= wav[i]-1; mi++){
                   3502:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3503:          for (j=1;j<=nlstate+ndeath;j++){
                   3504:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3505:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3506:          }
                   3507:        for(d=0; d<dh[mi][i]; d++){
                   3508:          newm=savm;
                   3509:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3510:          cov[2]=agexact;
                   3511:          if(nagesqr==1)
                   3512:            cov[3]= agexact*agexact;
                   3513:          for (kk=1; kk<=cptcovage;kk++) {
                   3514:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3515:          }
1.126     brouard  3516:        
1.226     brouard  3517:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3518:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3519:          savm=oldm;
                   3520:          oldm=newm;
                   3521:        } /* end mult */
                   3522:       
                   3523:        s1=s[mw[mi][i]][i];
                   3524:        s2=s[mw[mi+1][i]][i];
                   3525:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3526:        ipmx +=1;
                   3527:        sw += weight[i];
                   3528:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3529:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3530:       } /* end of wave */
                   3531:     } /* end of individual */
                   3532:   } /* End of if */
                   3533:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3534:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3535:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3536:   return -l;
1.126     brouard  3537: }
                   3538: 
                   3539: /*************** log-likelihood *************/
                   3540: double funcone( double *x)
                   3541: {
1.228     brouard  3542:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3543:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3544:   int ioffset=0;
1.131     brouard  3545:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3546:   double **out;
                   3547:   double lli; /* Individual log likelihood */
                   3548:   double llt;
                   3549:   int s1, s2;
1.228     brouard  3550:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3551: 
1.126     brouard  3552:   double bbh, survp;
1.187     brouard  3553:   double agexact;
1.214     brouard  3554:   double agebegin, ageend;
1.126     brouard  3555:   /*extern weight */
                   3556:   /* We are differentiating ll according to initial status */
                   3557:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3558:   /*for(i=1;i<imx;i++) 
                   3559:     printf(" %d\n",s[4][i]);
                   3560:   */
                   3561:   cov[1]=1.;
                   3562: 
                   3563:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3564:   ioffset=0;
                   3565:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3566:     /* ioffset=2+nagesqr+cptcovage; */
                   3567:     ioffset=2+nagesqr;
1.232     brouard  3568:     /* Fixed */
1.224     brouard  3569:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3570:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3571:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3572:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3573: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3574: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3575: /*    cov[2+6]=covar[2][i]; V2  */
                   3576: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3577: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3578: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3579: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3580: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3581: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3582:     }
1.232     brouard  3583:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3584:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3585:     /* } */
1.231     brouard  3586:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3587:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3588:     /* } */
1.225     brouard  3589:     
1.233     brouard  3590: 
                   3591:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3592:     /* Wave varying (but not age varying) */
                   3593:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3594:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3595:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3596:       }
1.232     brouard  3597:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3598:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3599:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3600:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3601:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3602:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3603:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3604:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3605:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3606:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3607:       /* } */
1.126     brouard  3608:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3609:        for (j=1;j<=nlstate+ndeath;j++){
                   3610:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3611:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3612:        }
1.214     brouard  3613:       
                   3614:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3615:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3616:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3617:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3618:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3619:          and mw[mi+1][i]. dh depends on stepm.*/
                   3620:        newm=savm;
1.247     brouard  3621:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3622:        cov[2]=agexact;
                   3623:        if(nagesqr==1)
                   3624:          cov[3]= agexact*agexact;
                   3625:        for (kk=1; kk<=cptcovage;kk++) {
                   3626:          if(!FixedV[Tvar[Tage[kk]]])
                   3627:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3628:          else
                   3629:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3630:        }
                   3631:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3632:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3633:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3634:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3635:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3636:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3637:        savm=oldm;
                   3638:        oldm=newm;
1.126     brouard  3639:       } /* end mult */
                   3640:       
                   3641:       s1=s[mw[mi][i]][i];
                   3642:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3643:       /* if(s2==-1){ */
                   3644:       /*       printf(" s1=%d, s2=%d i=%d \n", s1, s2, i); */
                   3645:       /*       /\* exit(1); *\/ */
                   3646:       /* } */
1.126     brouard  3647:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3648:       /* bias is positive if real duration
                   3649:        * is higher than the multiple of stepm and negative otherwise.
                   3650:        */
                   3651:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3652:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3653:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3654:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3655:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3656:        lli= log(survp);
1.126     brouard  3657:       }else if (mle==1){
1.242     brouard  3658:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3659:       } else if(mle==2){
1.242     brouard  3660:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3661:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3662:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3663:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3664:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3665:       } else{  /* mle=0 back to 1 */
1.242     brouard  3666:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3667:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3668:       } /* End of if */
                   3669:       ipmx +=1;
                   3670:       sw += weight[i];
                   3671:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3672:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3673:       if(globpr){
1.246     brouard  3674:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3675:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3676:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
                   3677:                2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
                   3678:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3679:          llt +=ll[k]*gipmx/gsw;
                   3680:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3681:        }
                   3682:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3683:       }
1.232     brouard  3684:        } /* end of wave */
                   3685: } /* end of individual */
                   3686: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3687: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3688: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3689: if(globpr==0){ /* First time we count the contributions and weights */
                   3690:        gipmx=ipmx;
                   3691:        gsw=sw;
                   3692: }
                   3693: return -l;
1.126     brouard  3694: }
                   3695: 
                   3696: 
                   3697: /*************** function likelione ***********/
                   3698: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3699: {
                   3700:   /* This routine should help understanding what is done with 
                   3701:      the selection of individuals/waves and
                   3702:      to check the exact contribution to the likelihood.
                   3703:      Plotting could be done.
                   3704:    */
                   3705:   int k;
                   3706: 
                   3707:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3708:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3709:     strcat(fileresilk,fileresu);
1.126     brouard  3710:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3711:       printf("Problem with resultfile: %s\n", fileresilk);
                   3712:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3713:     }
1.214     brouard  3714:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3715:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3716:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3717:     for(k=1; k<=nlstate; k++) 
                   3718:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3719:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3720:   }
                   3721: 
                   3722:   *fretone=(*funcone)(p);
                   3723:   if(*globpri !=0){
                   3724:     fclose(ficresilk);
1.205     brouard  3725:     if (mle ==0)
                   3726:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3727:     else if(mle >=1)
                   3728:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3729:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3730:     
1.208     brouard  3731:       
                   3732:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3733:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3734: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3735:     }
1.207     brouard  3736:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3737: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3738:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3739: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3740:     fflush(fichtm);
1.205     brouard  3741:   }
1.126     brouard  3742:   return;
                   3743: }
                   3744: 
                   3745: 
                   3746: /*********** Maximum Likelihood Estimation ***************/
                   3747: 
                   3748: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3749: {
1.165     brouard  3750:   int i,j, iter=0;
1.126     brouard  3751:   double **xi;
                   3752:   double fret;
                   3753:   double fretone; /* Only one call to likelihood */
                   3754:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3755: 
                   3756: #ifdef NLOPT
                   3757:   int creturn;
                   3758:   nlopt_opt opt;
                   3759:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3760:   double *lb;
                   3761:   double minf; /* the minimum objective value, upon return */
                   3762:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3763:   myfunc_data dinst, *d = &dinst;
                   3764: #endif
                   3765: 
                   3766: 
1.126     brouard  3767:   xi=matrix(1,npar,1,npar);
                   3768:   for (i=1;i<=npar;i++)
                   3769:     for (j=1;j<=npar;j++)
                   3770:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3771:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3772:   strcpy(filerespow,"POW_"); 
1.126     brouard  3773:   strcat(filerespow,fileres);
                   3774:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3775:     printf("Problem with resultfile: %s\n", filerespow);
                   3776:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3777:   }
                   3778:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3779:   for (i=1;i<=nlstate;i++)
                   3780:     for(j=1;j<=nlstate+ndeath;j++)
                   3781:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3782:   fprintf(ficrespow,"\n");
1.162     brouard  3783: #ifdef POWELL
1.126     brouard  3784:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3785: #endif
1.126     brouard  3786: 
1.162     brouard  3787: #ifdef NLOPT
                   3788: #ifdef NEWUOA
                   3789:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3790: #else
                   3791:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3792: #endif
                   3793:   lb=vector(0,npar-1);
                   3794:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3795:   nlopt_set_lower_bounds(opt, lb);
                   3796:   nlopt_set_initial_step1(opt, 0.1);
                   3797:   
                   3798:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3799:   d->function = func;
                   3800:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3801:   nlopt_set_min_objective(opt, myfunc, d);
                   3802:   nlopt_set_xtol_rel(opt, ftol);
                   3803:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3804:     printf("nlopt failed! %d\n",creturn); 
                   3805:   }
                   3806:   else {
                   3807:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3808:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3809:     iter=1; /* not equal */
                   3810:   }
                   3811:   nlopt_destroy(opt);
                   3812: #endif
1.126     brouard  3813:   free_matrix(xi,1,npar,1,npar);
                   3814:   fclose(ficrespow);
1.203     brouard  3815:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3816:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3817:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3818: 
                   3819: }
                   3820: 
                   3821: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3822: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3823: {
                   3824:   double  **a,**y,*x,pd;
1.203     brouard  3825:   /* double **hess; */
1.164     brouard  3826:   int i, j;
1.126     brouard  3827:   int *indx;
                   3828: 
                   3829:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3830:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3831:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3832:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3833:   double gompertz(double p[]);
1.203     brouard  3834:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3835: 
                   3836:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3837:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3838:   for (i=1;i<=npar;i++){
1.203     brouard  3839:     printf("%d-",i);fflush(stdout);
                   3840:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3841:    
                   3842:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3843:     
                   3844:     /*  printf(" %f ",p[i]);
                   3845:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3846:   }
                   3847:   
                   3848:   for (i=1;i<=npar;i++) {
                   3849:     for (j=1;j<=npar;j++)  {
                   3850:       if (j>i) { 
1.203     brouard  3851:        printf(".%d-%d",i,j);fflush(stdout);
                   3852:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3853:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3854:        
                   3855:        hess[j][i]=hess[i][j];    
                   3856:        /*printf(" %lf ",hess[i][j]);*/
                   3857:       }
                   3858:     }
                   3859:   }
                   3860:   printf("\n");
                   3861:   fprintf(ficlog,"\n");
                   3862: 
                   3863:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3864:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3865:   
                   3866:   a=matrix(1,npar,1,npar);
                   3867:   y=matrix(1,npar,1,npar);
                   3868:   x=vector(1,npar);
                   3869:   indx=ivector(1,npar);
                   3870:   for (i=1;i<=npar;i++)
                   3871:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3872:   ludcmp(a,npar,indx,&pd);
                   3873: 
                   3874:   for (j=1;j<=npar;j++) {
                   3875:     for (i=1;i<=npar;i++) x[i]=0;
                   3876:     x[j]=1;
                   3877:     lubksb(a,npar,indx,x);
                   3878:     for (i=1;i<=npar;i++){ 
                   3879:       matcov[i][j]=x[i];
                   3880:     }
                   3881:   }
                   3882: 
                   3883:   printf("\n#Hessian matrix#\n");
                   3884:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   3885:   for (i=1;i<=npar;i++) { 
                   3886:     for (j=1;j<=npar;j++) { 
1.203     brouard  3887:       printf("%.6e ",hess[i][j]);
                   3888:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  3889:     }
                   3890:     printf("\n");
                   3891:     fprintf(ficlog,"\n");
                   3892:   }
                   3893: 
1.203     brouard  3894:   /* printf("\n#Covariance matrix#\n"); */
                   3895:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   3896:   /* for (i=1;i<=npar;i++) {  */
                   3897:   /*   for (j=1;j<=npar;j++) {  */
                   3898:   /*     printf("%.6e ",matcov[i][j]); */
                   3899:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   3900:   /*   } */
                   3901:   /*   printf("\n"); */
                   3902:   /*   fprintf(ficlog,"\n"); */
                   3903:   /* } */
                   3904: 
1.126     brouard  3905:   /* Recompute Inverse */
1.203     brouard  3906:   /* for (i=1;i<=npar;i++) */
                   3907:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   3908:   /* ludcmp(a,npar,indx,&pd); */
                   3909: 
                   3910:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   3911: 
                   3912:   /* for (j=1;j<=npar;j++) { */
                   3913:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   3914:   /*   x[j]=1; */
                   3915:   /*   lubksb(a,npar,indx,x); */
                   3916:   /*   for (i=1;i<=npar;i++){  */
                   3917:   /*     y[i][j]=x[i]; */
                   3918:   /*     printf("%.3e ",y[i][j]); */
                   3919:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   3920:   /*   } */
                   3921:   /*   printf("\n"); */
                   3922:   /*   fprintf(ficlog,"\n"); */
                   3923:   /* } */
                   3924: 
                   3925:   /* Verifying the inverse matrix */
                   3926: #ifdef DEBUGHESS
                   3927:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  3928: 
1.203     brouard  3929:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   3930:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  3931: 
                   3932:   for (j=1;j<=npar;j++) {
                   3933:     for (i=1;i<=npar;i++){ 
1.203     brouard  3934:       printf("%.2f ",y[i][j]);
                   3935:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  3936:     }
                   3937:     printf("\n");
                   3938:     fprintf(ficlog,"\n");
                   3939:   }
1.203     brouard  3940: #endif
1.126     brouard  3941: 
                   3942:   free_matrix(a,1,npar,1,npar);
                   3943:   free_matrix(y,1,npar,1,npar);
                   3944:   free_vector(x,1,npar);
                   3945:   free_ivector(indx,1,npar);
1.203     brouard  3946:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  3947: 
                   3948: 
                   3949: }
                   3950: 
                   3951: /*************** hessian matrix ****************/
                   3952: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  3953: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  3954:   int i;
                   3955:   int l=1, lmax=20;
1.203     brouard  3956:   double k1,k2, res, fx;
1.132     brouard  3957:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  3958:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   3959:   int k=0,kmax=10;
                   3960:   double l1;
                   3961: 
                   3962:   fx=func(x);
                   3963:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  3964:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  3965:     l1=pow(10,l);
                   3966:     delts=delt;
                   3967:     for(k=1 ; k <kmax; k=k+1){
                   3968:       delt = delta*(l1*k);
                   3969:       p2[theta]=x[theta] +delt;
1.145     brouard  3970:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  3971:       p2[theta]=x[theta]-delt;
                   3972:       k2=func(p2)-fx;
                   3973:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  3974:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  3975:       
1.203     brouard  3976: #ifdef DEBUGHESSII
1.126     brouard  3977:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3978:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3979: #endif
                   3980:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   3981:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   3982:        k=kmax;
                   3983:       }
                   3984:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  3985:        k=kmax; l=lmax*10;
1.126     brouard  3986:       }
                   3987:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   3988:        delts=delt;
                   3989:       }
1.203     brouard  3990:     } /* End loop k */
1.126     brouard  3991:   }
                   3992:   delti[theta]=delts;
                   3993:   return res; 
                   3994:   
                   3995: }
                   3996: 
1.203     brouard  3997: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  3998: {
                   3999:   int i;
1.164     brouard  4000:   int l=1, lmax=20;
1.126     brouard  4001:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4002:   double p2[MAXPARM+1];
1.203     brouard  4003:   int k, kmax=1;
                   4004:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4005: 
                   4006:   int firstime=0;
1.203     brouard  4007:   
1.126     brouard  4008:   fx=func(x);
1.203     brouard  4009:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4010:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4011:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4012:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4013:     k1=func(p2)-fx;
                   4014:   
1.203     brouard  4015:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4016:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4017:     k2=func(p2)-fx;
                   4018:   
1.203     brouard  4019:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4020:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4021:     k3=func(p2)-fx;
                   4022:   
1.203     brouard  4023:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4024:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4025:     k4=func(p2)-fx;
1.203     brouard  4026:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4027:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4028:       firstime=1;
1.203     brouard  4029:       kmax=kmax+10;
1.208     brouard  4030:     }
                   4031:     if(kmax >=10 || firstime ==1){
1.246     brouard  4032:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4033:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4034:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4035:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4036:     }
                   4037: #ifdef DEBUGHESSIJ
                   4038:     v1=hess[thetai][thetai];
                   4039:     v2=hess[thetaj][thetaj];
                   4040:     cv12=res;
                   4041:     /* Computing eigen value of Hessian matrix */
                   4042:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4043:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4044:     if ((lc2 <0) || (lc1 <0) ){
                   4045:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4046:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4047:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4048:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4049:     }
1.126     brouard  4050: #endif
                   4051:   }
                   4052:   return res;
                   4053: }
                   4054: 
1.203     brouard  4055:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4056: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4057: /* { */
                   4058: /*   int i; */
                   4059: /*   int l=1, lmax=20; */
                   4060: /*   double k1,k2,k3,k4,res,fx; */
                   4061: /*   double p2[MAXPARM+1]; */
                   4062: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4063: /*   int k=0,kmax=10; */
                   4064: /*   double l1; */
                   4065:   
                   4066: /*   fx=func(x); */
                   4067: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4068: /*     l1=pow(10,l); */
                   4069: /*     delts=delt; */
                   4070: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4071: /*       delt = delti*(l1*k); */
                   4072: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4073: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4074: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4075: /*       k1=func(p2)-fx; */
                   4076:       
                   4077: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4078: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4079: /*       k2=func(p2)-fx; */
                   4080:       
                   4081: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4082: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4083: /*       k3=func(p2)-fx; */
                   4084:       
                   4085: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4086: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4087: /*       k4=func(p2)-fx; */
                   4088: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4089: /* #ifdef DEBUGHESSIJ */
                   4090: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4091: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4092: /* #endif */
                   4093: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4094: /*     k=kmax; */
                   4095: /*       } */
                   4096: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4097: /*     k=kmax; l=lmax*10; */
                   4098: /*       } */
                   4099: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4100: /*     delts=delt; */
                   4101: /*       } */
                   4102: /*     } /\* End loop k *\/ */
                   4103: /*   } */
                   4104: /*   delti[theta]=delts; */
                   4105: /*   return res;  */
                   4106: /* } */
                   4107: 
                   4108: 
1.126     brouard  4109: /************** Inverse of matrix **************/
                   4110: void ludcmp(double **a, int n, int *indx, double *d) 
                   4111: { 
                   4112:   int i,imax,j,k; 
                   4113:   double big,dum,sum,temp; 
                   4114:   double *vv; 
                   4115:  
                   4116:   vv=vector(1,n); 
                   4117:   *d=1.0; 
                   4118:   for (i=1;i<=n;i++) { 
                   4119:     big=0.0; 
                   4120:     for (j=1;j<=n;j++) 
                   4121:       if ((temp=fabs(a[i][j])) > big) big=temp; 
                   4122:     if (big == 0.0) nrerror("Singular matrix in routine ludcmp"); 
                   4123:     vv[i]=1.0/big; 
                   4124:   } 
                   4125:   for (j=1;j<=n;j++) { 
                   4126:     for (i=1;i<j;i++) { 
                   4127:       sum=a[i][j]; 
                   4128:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4129:       a[i][j]=sum; 
                   4130:     } 
                   4131:     big=0.0; 
                   4132:     for (i=j;i<=n;i++) { 
                   4133:       sum=a[i][j]; 
                   4134:       for (k=1;k<j;k++) 
                   4135:        sum -= a[i][k]*a[k][j]; 
                   4136:       a[i][j]=sum; 
                   4137:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4138:        big=dum; 
                   4139:        imax=i; 
                   4140:       } 
                   4141:     } 
                   4142:     if (j != imax) { 
                   4143:       for (k=1;k<=n;k++) { 
                   4144:        dum=a[imax][k]; 
                   4145:        a[imax][k]=a[j][k]; 
                   4146:        a[j][k]=dum; 
                   4147:       } 
                   4148:       *d = -(*d); 
                   4149:       vv[imax]=vv[j]; 
                   4150:     } 
                   4151:     indx[j]=imax; 
                   4152:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4153:     if (j != n) { 
                   4154:       dum=1.0/(a[j][j]); 
                   4155:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4156:     } 
                   4157:   } 
                   4158:   free_vector(vv,1,n);  /* Doesn't work */
                   4159: ;
                   4160: } 
                   4161: 
                   4162: void lubksb(double **a, int n, int *indx, double b[]) 
                   4163: { 
                   4164:   int i,ii=0,ip,j; 
                   4165:   double sum; 
                   4166:  
                   4167:   for (i=1;i<=n;i++) { 
                   4168:     ip=indx[i]; 
                   4169:     sum=b[ip]; 
                   4170:     b[ip]=b[i]; 
                   4171:     if (ii) 
                   4172:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4173:     else if (sum) ii=i; 
                   4174:     b[i]=sum; 
                   4175:   } 
                   4176:   for (i=n;i>=1;i--) { 
                   4177:     sum=b[i]; 
                   4178:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4179:     b[i]=sum/a[i][i]; 
                   4180:   } 
                   4181: } 
                   4182: 
                   4183: void pstamp(FILE *fichier)
                   4184: {
1.196     brouard  4185:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4186: }
                   4187: 
                   4188: /************ Frequencies ********************/
1.251   ! brouard  4189: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4190:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4191:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4192: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4193:   
1.250     brouard  4194:   int i, m, jk, j1, bool, z1,j, k, iv, jj=0;
1.226     brouard  4195:   int iind=0, iage=0;
                   4196:   int mi; /* Effective wave */
                   4197:   int first;
                   4198:   double ***freq; /* Frequencies */
                   4199:   double *meanq;
                   4200:   double **meanqt;
                   4201:   double *pp, **prop, *posprop, *pospropt;
                   4202:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4203:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4204:   double agebegin, ageend;
                   4205:     
                   4206:   pp=vector(1,nlstate);
1.251   ! brouard  4207:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4208:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4209:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4210:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4211:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4212:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4213:   strcpy(fileresp,"P_");
                   4214:   strcat(fileresp,fileresu);
                   4215:   /*strcat(fileresphtm,fileresu);*/
                   4216:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4217:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4218:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4219:     exit(0);
                   4220:   }
1.240     brouard  4221:   
1.226     brouard  4222:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4223:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4224:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4225:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4226:     fflush(ficlog);
                   4227:     exit(70); 
                   4228:   }
                   4229:   else{
                   4230:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4231: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4232: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4233:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4234:   }
1.237     brouard  4235:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4236:   
1.226     brouard  4237:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4238:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4239:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4240:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4241:     fflush(ficlog);
                   4242:     exit(70); 
1.240     brouard  4243:   } else{
1.226     brouard  4244:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4245: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4246: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4247:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4248:   }
1.240     brouard  4249:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4250:   
1.251   ! brouard  4251:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4252:   j1=0;
1.126     brouard  4253:   
1.227     brouard  4254:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4255:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4256:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4257:   
                   4258:   
1.226     brouard  4259:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4260:      reference=low_education V1=0,V2=0
                   4261:      med_educ                V1=1 V2=0, 
                   4262:      high_educ               V1=0 V2=1
                   4263:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4264:   */
1.249     brouard  4265:   dateintsum=0;
                   4266:   k2cpt=0;
                   4267: 
1.251   ! brouard  4268:   for (j = 0; j <= cptcoveff; j+=cptcoveff){   /* j= 0 constant model */
        !          4269:     first=1;
        !          4270:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on covariates combination in order of model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
        !          4271:       posproptt=0.;
        !          4272:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
        !          4273:        scanf("%d", i);*/
        !          4274:       for (i=-5; i<=nlstate+ndeath; i++)  
        !          4275:        for (jk=-5; jk<=nlstate+ndeath; jk++)  
        !          4276:          for(m=iagemin; m <= iagemax+3; m++)
        !          4277:            freq[i][jk][m]=0;
        !          4278:       
        !          4279:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4280:        for(m=iagemin; m <= iagemax+3; m++)
1.251   ! brouard  4281:          prop[i][m]=0;
        !          4282:        posprop[i]=0;
        !          4283:        pospropt[i]=0;
        !          4284:       }
        !          4285:       /* for (z1=1; z1<= nqfveff; z1++) {   */
        !          4286:       /*   meanq[z1]+=0.; */
        !          4287:       /*   for(m=1;m<=lastpass;m++){ */
        !          4288:       /*       meanqt[m][z1]=0.; */
        !          4289:       /*   } */
        !          4290:       /* } */
        !          4291:       
        !          4292:       /* dateintsum=0; */
        !          4293:       /* k2cpt=0; */
        !          4294:       
        !          4295:       /* For that combination of covariate j1, we count and print the frequencies in one pass */
        !          4296:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
        !          4297:        bool=1;
        !          4298:        if(j !=0){
        !          4299:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
        !          4300:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
        !          4301:              /* for (z1=1; z1<= nqfveff; z1++) {   */
        !          4302:              /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
        !          4303:              /* } */
        !          4304:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
        !          4305:                /* if(Tvaraff[z1] ==-20){ */
        !          4306:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
        !          4307:                /* }else  if(Tvaraff[z1] ==-10){ */
        !          4308:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
        !          4309:                /* }else  */
        !          4310:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
        !          4311:                  /* Tests if this individual iind responded to combination j1 (V4=1 V3=0) */
        !          4312:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
        !          4313:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
        !          4314:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
        !          4315:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
        !          4316:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
        !          4317:                } /* Onlyf fixed */
        !          4318:              } /* end z1 */
        !          4319:            } /* cptcovn > 0 */
        !          4320:          } /* end any */
        !          4321:        }/* end j==0 */
        !          4322:        if (bool==1){ /* We selected an individual iind satisfying combination j1 or all fixed */
        !          4323:          /* for(m=firstpass; m<=lastpass; m++){ */
        !          4324:          for(mi=1; mi<wav[iind];mi++){ /* For that wave */
        !          4325:            m=mw[mi][iind];
        !          4326:            if(j!=0){
        !          4327:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
        !          4328:                for (z1=1; z1<=cptcoveff; z1++) {
        !          4329:                  if( Fixed[Tmodelind[z1]]==1){
        !          4330:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
        !          4331:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
        !          4332:                                                                                      value is -1, we don't select. It differs from the 
        !          4333:                                                                                      constant and age model which counts them. */
        !          4334:                      bool=0; /* not selected */
        !          4335:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
        !          4336:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
        !          4337:                      bool=0;
        !          4338:                    }
        !          4339:                  }
        !          4340:                }
        !          4341:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
        !          4342:            } /* end j==0 */
        !          4343:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
        !          4344:            if(bool==1){
        !          4345:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
        !          4346:                 and mw[mi+1][iind]. dh depends on stepm. */
        !          4347:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
        !          4348:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
        !          4349:              if(m >=firstpass && m <=lastpass){
        !          4350:                k2=anint[m][iind]+(mint[m][iind]/12.);
        !          4351:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
        !          4352:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
        !          4353:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
        !          4354:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
        !          4355:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
        !          4356:                if (m<lastpass) {
        !          4357:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
        !          4358:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
        !          4359:                  if(s[m][iind]==-1)
        !          4360:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
        !          4361:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
        !          4362:                  /* if((int)agev[m][iind] == 55) */
        !          4363:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
        !          4364:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
        !          4365:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4366:                }
1.251   ! brouard  4367:              } /* end if between passes */  
        !          4368:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
        !          4369:                dateintsum=dateintsum+k2; /* on all covariates ?*/
        !          4370:                k2cpt++;
        !          4371:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4372:              }
1.251   ! brouard  4373:            }else{
        !          4374:              bool=1;
        !          4375:            }/* end bool 2 */
        !          4376:          } /* end m */
        !          4377:        } /* end bool */
        !          4378:       } /* end iind = 1 to imx */
        !          4379:       /* prop[s][age] is feeded for any initial and valid live state as well as
        !          4380:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
        !          4381:       
        !          4382:       
        !          4383:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
        !          4384:       pstamp(ficresp);
        !          4385:       if  (cptcoveff>0 && j!=0){
        !          4386:        printf( "\n#********** Variable "); 
        !          4387:        fprintf(ficresp, "\n#********** Variable "); 
        !          4388:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
        !          4389:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
        !          4390:        fprintf(ficlog, "\n#********** Variable "); 
        !          4391:        for (z1=1; z1<=cptcoveff; z1++){
        !          4392:          if(!FixedV[Tvaraff[z1]]){
        !          4393:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
        !          4394:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
        !          4395:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
        !          4396:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
        !          4397:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4398:          }else{
1.251   ! brouard  4399:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
        !          4400:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
        !          4401:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
        !          4402:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
        !          4403:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
        !          4404:          }
        !          4405:        }
        !          4406:        printf( "**********\n#");
        !          4407:        fprintf(ficresp, "**********\n#");
        !          4408:        fprintf(ficresphtm, "**********</h3>\n");
        !          4409:        fprintf(ficresphtmfr, "**********</h3>\n");
        !          4410:        fprintf(ficlog, "**********\n");
        !          4411:       }
        !          4412:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
        !          4413:       for(i=1; i<=nlstate;i++) {
        !          4414:        fprintf(ficresp, " Age Prev(%d)  N(%d)  N  ",i,i);
        !          4415:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
        !          4416:       }
        !          4417:       fprintf(ficresp, "\n");
        !          4418:       fprintf(ficresphtm, "\n");
        !          4419:       
        !          4420:       /* Header of frequency table by age */
        !          4421:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
        !          4422:       fprintf(ficresphtmfr,"<th>Age</th> ");
        !          4423:       for(jk=-1; jk <=nlstate+ndeath; jk++){
        !          4424:        for(m=-1; m <=nlstate+ndeath; m++){
        !          4425:          if(jk!=0 && m!=0)
        !          4426:            fprintf(ficresphtmfr,"<th>%d%d</th> ",jk,m);
1.240     brouard  4427:        }
1.226     brouard  4428:       }
1.251   ! brouard  4429:       fprintf(ficresphtmfr, "\n");
        !          4430:     
        !          4431:       /* For each age */
        !          4432:       for(iage=iagemin; iage <= iagemax+3; iage++){
        !          4433:        fprintf(ficresphtm,"<tr>");
        !          4434:        if(iage==iagemax+1){
        !          4435:          fprintf(ficlog,"1");
        !          4436:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
        !          4437:        }else if(iage==iagemax+2){
        !          4438:          fprintf(ficlog,"0");
        !          4439:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
        !          4440:        }else if(iage==iagemax+3){
        !          4441:          fprintf(ficlog,"Total");
        !          4442:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
        !          4443:        }else{
1.240     brouard  4444:          if(first==1){
1.251   ! brouard  4445:            first=0;
        !          4446:            printf("See log file for details...\n");
        !          4447:          }
        !          4448:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
        !          4449:          fprintf(ficlog,"Age %d", iage);
        !          4450:        }
        !          4451:        for(jk=1; jk <=nlstate ; jk++){
        !          4452:          for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
        !          4453:            pp[jk] += freq[jk][m][iage]; 
        !          4454:        }
        !          4455:        for(jk=1; jk <=nlstate ; jk++){
        !          4456:          for(m=-1, pos=0; m <=0 ; m++)
        !          4457:            pos += freq[jk][m][iage];
        !          4458:          if(pp[jk]>=1.e-10){
        !          4459:            if(first==1){
        !          4460:              printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
        !          4461:            }
        !          4462:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
        !          4463:          }else{
        !          4464:            if(first==1)
        !          4465:              printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
        !          4466:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
1.240     brouard  4467:          }
                   4468:        }
                   4469:       
1.251   ! brouard  4470:        for(jk=1; jk <=nlstate ; jk++){ 
        !          4471:          /* posprop[jk]=0; */
        !          4472:          for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
        !          4473:            pp[jk] += freq[jk][m][iage];
        !          4474:        }       /* pp[jk] is the total number of transitions starting from state jk and any ending status until this age */
        !          4475:       
        !          4476:        for(jk=1,pos=0, pospropta=0.; jk <=nlstate ; jk++){
        !          4477:          pos += pp[jk]; /* pos is the total number of transitions until this age */
        !          4478:          posprop[jk] += prop[jk][iage]; /* prop is the number of transitions from a live state
        !          4479:                                            from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
        !          4480:          pospropta += prop[jk][iage]; /* prop is the number of transitions from a live state
1.240     brouard  4481:                                          from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4482:        }
1.251   ! brouard  4483:        for(jk=1; jk <=nlstate ; jk++){
1.240     brouard  4484:          if(pos>=1.e-5){
1.251   ! brouard  4485:            if(first==1)
        !          4486:              printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
        !          4487:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
        !          4488:          }else{
        !          4489:            if(first==1)
        !          4490:              printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
        !          4491:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
        !          4492:          }
        !          4493:          if( iage <= iagemax){
        !          4494:            if(pos>=1.e-5){
        !          4495:              fprintf(ficresp," %d %.5f %.0f %.0f",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
        !          4496:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
        !          4497:              /*probs[iage][jk][j1]= pp[jk]/pos;*/
        !          4498:              /*printf("\niage=%d jk=%d j1=%d %.5f %.0f %.0f %f",iage,jk,j1,pp[jk]/pos, pp[jk],pos,probs[iage][jk][j1]);*/
        !          4499:            }
        !          4500:            else{
        !          4501:              fprintf(ficresp," %d NaNq %.0f %.0f",iage,prop[jk][iage],pospropta);
        !          4502:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[jk][iage],pospropta);
        !          4503:            }
1.240     brouard  4504:          }
1.251   ! brouard  4505:          pospropt[jk] +=posprop[jk];
        !          4506:        } /* end loop jk */
        !          4507:        /* pospropt=0.; */
        !          4508:        for(jk=-1; jk <=nlstate+ndeath; jk++){
        !          4509:          for(m=-1; m <=nlstate+ndeath; m++){
        !          4510:            if(freq[jk][m][iage] !=0 ) { /* minimizing output */
        !          4511:              if(first==1){
        !          4512:                printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]);
        !          4513:              }
        !          4514:              fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iage]);
        !          4515:            }
        !          4516:            if(jk!=0 && m!=0)
        !          4517:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[jk][m][iage]);
1.240     brouard  4518:          }
1.251   ! brouard  4519:        } /* end loop jk */
        !          4520:        posproptt=0.; 
        !          4521:        for(jk=1; jk <=nlstate; jk++){
        !          4522:          posproptt += pospropt[jk];
        !          4523:        }
        !          4524:        fprintf(ficresphtmfr,"</tr>\n ");
        !          4525:        if(iage <= iagemax){
        !          4526:          fprintf(ficresp,"\n");
        !          4527:          fprintf(ficresphtm,"</tr>\n");
1.240     brouard  4528:        }
1.251   ! brouard  4529:        if(first==1)
        !          4530:          printf("Others in log...\n");
        !          4531:        fprintf(ficlog,"\n");
        !          4532:       } /* end loop age iage */
        !          4533:       fprintf(ficresphtm,"<tr><th>Tot</th>");
        !          4534:       for(jk=1; jk <=nlstate ; jk++){
        !          4535:        if(posproptt < 1.e-5){
        !          4536:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[jk],posproptt); 
        !          4537:        }else{
        !          4538:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[jk]/posproptt,pospropt[jk],posproptt);  
1.240     brouard  4539:        }
1.226     brouard  4540:       }
1.251   ! brouard  4541:       fprintf(ficresphtm,"</tr>\n");
        !          4542:       fprintf(ficresphtm,"</table>\n");
        !          4543:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4544:       if(posproptt < 1.e-5){
1.251   ! brouard  4545:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
        !          4546:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
        !          4547:        fprintf(ficres,"\n  This combination (%d) is not valid and no result will be produced\n\n",j1);
        !          4548:        invalidvarcomb[j1]=1;
1.226     brouard  4549:       }else{
1.251   ! brouard  4550:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
        !          4551:        invalidvarcomb[j1]=0;
1.226     brouard  4552:       }
1.251   ! brouard  4553:       fprintf(ficresphtmfr,"</table>\n");
        !          4554:       fprintf(ficlog,"\n");
        !          4555:       if(j!=0){
        !          4556:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
        !          4557:        for(i=1,jk=1; i <=nlstate; i++){
        !          4558:          for(k=1; k <=(nlstate+ndeath); k++){
        !          4559:            if (k != i) {
        !          4560:              printf("%d%d ",i,k);
        !          4561:              fprintf(ficlog,"%d%d ",i,k);
        !          4562:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting jk */
        !          4563:                if(jj==1){  /* Constant case */
        !          4564:                  if(j1==1){ /* All dummy covariates to zero */
        !          4565:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
        !          4566:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
        !          4567:                  }
        !          4568:                  printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
        !          4569:                  fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
        !          4570:                  pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
        !          4571:                }else if( (log(j1-1)/log(2)+1 == jj -2 -nagesqr)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
        !          4572:                  pstart[jk]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
        !          4573:                  printf("jk=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",jk,i,k,jk,p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
        !          4574:                }else if(jj==2 || nagesqr==1){ /* age or age*age parameter */
        !          4575:                  ;
        !          4576:                }else{ /* Other cases, like quantitative fixed or varying covariates */
        !          4577:                  ;
        !          4578:                }
        !          4579:                /* printf("%12.7f )", param[i][jj][k]); */
        !          4580:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
        !          4581:                jk++; 
        !          4582:              } /* end jj */
        !          4583:              printf("\n");
        !          4584:              fprintf(ficlog,"\n");
        !          4585:            } /* end k!= i */
        !          4586:          } /* end k */
        !          4587:        } /* end i, jk */
        !          4588:       } /* end j !=0 */
        !          4589:     } /* end selected combination of covariate j1 */
        !          4590:     if(j==0){ /* We can estimate starting values from the occurences in each case */
        !          4591:       printf("#Freqsummary: Starting values for the constants:\n");
        !          4592:       fprintf(ficlog,"\n");
        !          4593:       for(i=1,jk=1; i <=nlstate; i++){
        !          4594:        for(k=1; k <=(nlstate+ndeath); k++){
        !          4595:          if (k != i) {
        !          4596:            printf("%d%d ",i,k);
        !          4597:            fprintf(ficlog,"%d%d ",i,k);
        !          4598:            for(jj=1; jj <=ncovmodel; jj++){
        !          4599:              if(jj==1){
        !          4600:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
        !          4601:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
        !          4602:              }
        !          4603:              /* printf("%12.7f )", param[i][jj][k]); */
        !          4604:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
        !          4605:              jk++; 
1.250     brouard  4606:            }
1.251   ! brouard  4607:            printf("\n");
        !          4608:            fprintf(ficlog,"\n");
1.250     brouard  4609:          }
                   4610:        }
                   4611:       }
1.251   ! brouard  4612:       printf("#Freqsummary\n");
        !          4613:       fprintf(ficlog,"\n");
        !          4614:       for(jk=-1; jk <=nlstate+ndeath; jk++){
        !          4615:        for(m=-1; m <=nlstate+ndeath; m++){
        !          4616:          /* param[i]|j][k]= freq[jk][m][iagemax+3] */
1.250     brouard  4617:          printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
                   4618:          fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
1.251   ! brouard  4619:          /* if(freq[jk][m][iage] !=0 ) { /\* minimizing output *\/ */
        !          4620:          /*   printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
        !          4621:          /*   fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
        !          4622:          /* } */
        !          4623:        }
        !          4624:       } /* end loop jk */
        !          4625:       
        !          4626:       printf("\n");
        !          4627:       fprintf(ficlog,"\n");
        !          4628:     } /* end j=0 */
1.249     brouard  4629:   } /* end j */
1.226     brouard  4630:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4631:   
1.226     brouard  4632:   fclose(ficresp);
                   4633:   fclose(ficresphtm);
                   4634:   fclose(ficresphtmfr);
                   4635:   free_vector(meanq,1,nqfveff);
                   4636:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.251   ! brouard  4637:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4638:   free_vector(pospropt,1,nlstate);
                   4639:   free_vector(posprop,1,nlstate);
1.251   ! brouard  4640:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4641:   free_vector(pp,1,nlstate);
                   4642:   /* End of freqsummary */
                   4643: }
1.126     brouard  4644: 
                   4645: /************ Prevalence ********************/
1.227     brouard  4646: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4647: {  
                   4648:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4649:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4650:      We still use firstpass and lastpass as another selection.
                   4651:   */
1.126     brouard  4652:  
1.227     brouard  4653:   int i, m, jk, j1, bool, z1,j, iv;
                   4654:   int mi; /* Effective wave */
                   4655:   int iage;
                   4656:   double agebegin, ageend;
                   4657: 
                   4658:   double **prop;
                   4659:   double posprop; 
                   4660:   double  y2; /* in fractional years */
                   4661:   int iagemin, iagemax;
                   4662:   int first; /** to stop verbosity which is redirected to log file */
                   4663: 
                   4664:   iagemin= (int) agemin;
                   4665:   iagemax= (int) agemax;
                   4666:   /*pp=vector(1,nlstate);*/
1.251   ! brouard  4667:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  4668:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4669:   j1=0;
1.222     brouard  4670:   
1.227     brouard  4671:   /*j=cptcoveff;*/
                   4672:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4673:   
1.227     brouard  4674:   first=1;
                   4675:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4676:     for (i=1; i<=nlstate; i++)  
1.251   ! brouard  4677:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  4678:        prop[i][iage]=0.0;
                   4679:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4680:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4681:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4682:     
                   4683:     for (i=1; i<=imx; i++) { /* Each individual */
                   4684:       bool=1;
                   4685:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4686:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4687:        m=mw[mi][i];
                   4688:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4689:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4690:        for (z1=1; z1<=cptcoveff; z1++){
                   4691:          if( Fixed[Tmodelind[z1]]==1){
                   4692:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4693:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4694:              bool=0;
                   4695:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4696:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4697:              bool=0;
                   4698:            }
                   4699:        }
                   4700:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4701:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4702:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4703:          if(m >=firstpass && m <=lastpass){
                   4704:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4705:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4706:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   4707:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251   ! brouard  4708:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  4709:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   4710:                exit(1);
                   4711:              }
                   4712:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   4713:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   4714:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   4715:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   4716:              } /* end valid statuses */ 
                   4717:            } /* end selection of dates */
                   4718:          } /* end selection of waves */
                   4719:        } /* end bool */
                   4720:       } /* end wave */
                   4721:     } /* end individual */
                   4722:     for(i=iagemin; i <= iagemax+3; i++){  
                   4723:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   4724:        posprop += prop[jk][i]; 
                   4725:       } 
                   4726:       
                   4727:       for(jk=1; jk <=nlstate ; jk++){      
                   4728:        if( i <=  iagemax){ 
                   4729:          if(posprop>=1.e-5){ 
                   4730:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   4731:          } else{
                   4732:            if(first==1){
                   4733:              first=0;
                   4734:              printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,j1,probs[i][jk][j1]);
                   4735:            }
                   4736:          }
                   4737:        } 
                   4738:       }/* end jk */ 
                   4739:     }/* end i */ 
1.222     brouard  4740:      /*} *//* end i1 */
1.227     brouard  4741:   } /* end j1 */
1.222     brouard  4742:   
1.227     brouard  4743:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   4744:   /*free_vector(pp,1,nlstate);*/
1.251   ! brouard  4745:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  4746: }  /* End of prevalence */
1.126     brouard  4747: 
                   4748: /************* Waves Concatenation ***************/
                   4749: 
                   4750: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   4751: {
                   4752:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   4753:      Death is a valid wave (if date is known).
                   4754:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   4755:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4756:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  4757:   */
1.126     brouard  4758: 
1.224     brouard  4759:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  4760:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   4761:      double sum=0., jmean=0.;*/
1.224     brouard  4762:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  4763:   int j, k=0,jk, ju, jl;
                   4764:   double sum=0.;
                   4765:   first=0;
1.214     brouard  4766:   firstwo=0;
1.217     brouard  4767:   firsthree=0;
1.218     brouard  4768:   firstfour=0;
1.164     brouard  4769:   jmin=100000;
1.126     brouard  4770:   jmax=-1;
                   4771:   jmean=0.;
1.224     brouard  4772: 
                   4773: /* Treating live states */
1.214     brouard  4774:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  4775:     mi=0;  /* First valid wave */
1.227     brouard  4776:     mli=0; /* Last valid wave */
1.126     brouard  4777:     m=firstpass;
1.214     brouard  4778:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  4779:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   4780:        mli=m-1;/* mw[++mi][i]=m-1; */
                   4781:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   4782:        mw[++mi][i]=m;
                   4783:        mli=m;
1.224     brouard  4784:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   4785:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  4786:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  4787:       }
1.227     brouard  4788:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  4789: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  4790:        break;
1.224     brouard  4791: #else
1.227     brouard  4792:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   4793:          if(firsthree == 0){
                   4794:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4795:            firsthree=1;
                   4796:          }
                   4797:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4798:          mw[++mi][i]=m;
                   4799:          mli=m;
                   4800:        }
                   4801:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   4802:          nbwarn++;
                   4803:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   4804:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4805:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4806:          }
                   4807:          break;
                   4808:        }
                   4809:        break;
1.224     brouard  4810: #endif
1.227     brouard  4811:       }/* End m >= lastpass */
1.126     brouard  4812:     }/* end while */
1.224     brouard  4813: 
1.227     brouard  4814:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  4815:     /* After last pass */
1.224     brouard  4816: /* Treating death states */
1.214     brouard  4817:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  4818:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   4819:       /* } */
1.126     brouard  4820:       mi++;    /* Death is another wave */
                   4821:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  4822:       /* Only death is a correct wave */
1.126     brouard  4823:       mw[mi][i]=m;
1.224     brouard  4824:     }
                   4825: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.227     brouard  4826:     else if ((int) andc[i] != 9999) { /* Status is negative. A death occured after lastpass, we can't take it into account because of potential bias */
1.216     brouard  4827:       /* m++; */
                   4828:       /* mi++; */
                   4829:       /* s[m][i]=nlstate+1;  /\* We are setting the status to the last of non live state *\/ */
                   4830:       /* mw[mi][i]=m; */
1.218     brouard  4831:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  4832:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   4833:          nbwarn++;
                   4834:          if(firstfiv==0){
                   4835:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4836:            firstfiv=1;
                   4837:          }else{
                   4838:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4839:          }
                   4840:        }else{ /* Death occured afer last wave potential bias */
                   4841:          nberr++;
                   4842:          if(firstwo==0){
                   4843:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4844:            firstwo=1;
                   4845:          }
                   4846:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4847:        }
1.218     brouard  4848:       }else{ /* end date of interview is known */
1.227     brouard  4849:        /* death is known but not confirmed by death status at any wave */
                   4850:        if(firstfour==0){
                   4851:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4852:          firstfour=1;
                   4853:        }
                   4854:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  4855:       }
1.224     brouard  4856:     } /* end if date of death is known */
                   4857: #endif
                   4858:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   4859:     /* wav[i]=mw[mi][i]; */
1.126     brouard  4860:     if(mi==0){
                   4861:       nbwarn++;
                   4862:       if(first==0){
1.227     brouard  4863:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   4864:        first=1;
1.126     brouard  4865:       }
                   4866:       if(first==1){
1.227     brouard  4867:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  4868:       }
                   4869:     } /* end mi==0 */
                   4870:   } /* End individuals */
1.214     brouard  4871:   /* wav and mw are no more changed */
1.223     brouard  4872:        
1.214     brouard  4873:   
1.126     brouard  4874:   for(i=1; i<=imx; i++){
                   4875:     for(mi=1; mi<wav[i];mi++){
                   4876:       if (stepm <=0)
1.227     brouard  4877:        dh[mi][i]=1;
1.126     brouard  4878:       else{
1.227     brouard  4879:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death */
                   4880:          if (agedc[i] < 2*AGESUP) {
                   4881:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   4882:            if(j==0) j=1;  /* Survives at least one month after exam */
                   4883:            else if(j<0){
                   4884:              nberr++;
                   4885:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4886:              j=1; /* Temporary Dangerous patch */
                   4887:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   4888:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4889:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   4890:            }
                   4891:            k=k+1;
                   4892:            if (j >= jmax){
                   4893:              jmax=j;
                   4894:              ijmax=i;
                   4895:            }
                   4896:            if (j <= jmin){
                   4897:              jmin=j;
                   4898:              ijmin=i;
                   4899:            }
                   4900:            sum=sum+j;
                   4901:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   4902:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   4903:          }
                   4904:        }
                   4905:        else{
                   4906:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  4907: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  4908:                                        
1.227     brouard  4909:          k=k+1;
                   4910:          if (j >= jmax) {
                   4911:            jmax=j;
                   4912:            ijmax=i;
                   4913:          }
                   4914:          else if (j <= jmin){
                   4915:            jmin=j;
                   4916:            ijmin=i;
                   4917:          }
                   4918:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   4919:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   4920:          if(j<0){
                   4921:            nberr++;
                   4922:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4923:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4924:          }
                   4925:          sum=sum+j;
                   4926:        }
                   4927:        jk= j/stepm;
                   4928:        jl= j -jk*stepm;
                   4929:        ju= j -(jk+1)*stepm;
                   4930:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   4931:          if(jl==0){
                   4932:            dh[mi][i]=jk;
                   4933:            bh[mi][i]=0;
                   4934:          }else{ /* We want a negative bias in order to only have interpolation ie
                   4935:                  * to avoid the price of an extra matrix product in likelihood */
                   4936:            dh[mi][i]=jk+1;
                   4937:            bh[mi][i]=ju;
                   4938:          }
                   4939:        }else{
                   4940:          if(jl <= -ju){
                   4941:            dh[mi][i]=jk;
                   4942:            bh[mi][i]=jl;       /* bias is positive if real duration
                   4943:                                 * is higher than the multiple of stepm and negative otherwise.
                   4944:                                 */
                   4945:          }
                   4946:          else{
                   4947:            dh[mi][i]=jk+1;
                   4948:            bh[mi][i]=ju;
                   4949:          }
                   4950:          if(dh[mi][i]==0){
                   4951:            dh[mi][i]=1; /* At least one step */
                   4952:            bh[mi][i]=ju; /* At least one step */
                   4953:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   4954:          }
                   4955:        } /* end if mle */
1.126     brouard  4956:       }
                   4957:     } /* end wave */
                   4958:   }
                   4959:   jmean=sum/k;
                   4960:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  4961:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  4962: }
1.126     brouard  4963: 
                   4964: /*********** Tricode ****************************/
1.220     brouard  4965:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  4966:  {
                   4967:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   4968:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   4969:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   4970:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   4971:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   4972:     */
1.130     brouard  4973: 
1.242     brouard  4974:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   4975:    int modmaxcovj=0; /* Modality max of covariates j */
                   4976:    int cptcode=0; /* Modality max of covariates j */
                   4977:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  4978: 
                   4979: 
1.242     brouard  4980:    /* cptcoveff=0;  */
                   4981:    /* *cptcov=0; */
1.126     brouard  4982:  
1.242     brouard  4983:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  4984: 
1.242     brouard  4985:    /* Loop on covariates without age and products and no quantitative variable */
                   4986:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   4987:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   4988:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   4989:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   4990:        switch(Fixed[k]) {
                   4991:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   4992:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   4993:           ij=(int)(covar[Tvar[k]][i]);
                   4994:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   4995:            * If product of Vn*Vm, still boolean *:
                   4996:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   4997:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   4998:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   4999:              modality of the nth covariate of individual i. */
                   5000:           if (ij > modmaxcovj)
                   5001:             modmaxcovj=ij; 
                   5002:           else if (ij < modmincovj) 
                   5003:             modmincovj=ij; 
                   5004:           if ((ij < -1) && (ij > NCOVMAX)){
                   5005:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5006:             exit(1);
                   5007:           }else
                   5008:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5009:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5010:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5011:           /* getting the maximum value of the modality of the covariate
                   5012:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5013:              female ies 1, then modmaxcovj=1.
                   5014:           */
                   5015:         } /* end for loop on individuals i */
                   5016:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5017:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5018:         cptcode=modmaxcovj;
                   5019:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5020:         /*for (i=0; i<=cptcode; i++) {*/
                   5021:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5022:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5023:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5024:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5025:             if( j != -1){
                   5026:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5027:                                  covariate for which somebody answered excluding 
                   5028:                                  undefined. Usually 2: 0 and 1. */
                   5029:             }
                   5030:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5031:                                     covariate for which somebody answered including 
                   5032:                                     undefined. Usually 3: -1, 0 and 1. */
                   5033:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5034:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5035:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5036:                        
1.242     brouard  5037:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5038:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5039:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5040:         /* modmincovj=3; modmaxcovj = 7; */
                   5041:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5042:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5043:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5044:         /* nbcode[Tvar[j]][ij]=k; */
                   5045:         /* nbcode[Tvar[j]][1]=0; */
                   5046:         /* nbcode[Tvar[j]][2]=1; */
                   5047:         /* nbcode[Tvar[j]][3]=2; */
                   5048:         /* To be continued (not working yet). */
                   5049:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5050:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5051:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5052:             break;
                   5053:           }
                   5054:           ij++;
                   5055:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5056:           cptcode = ij; /* New max modality for covar j */
                   5057:         } /* end of loop on modality i=-1 to 1 or more */
                   5058:         break;
                   5059:        case 1: /* Testing on varying covariate, could be simple and
                   5060:                * should look at waves or product of fixed *
                   5061:                * varying. No time to test -1, assuming 0 and 1 only */
                   5062:         ij=0;
                   5063:         for(i=0; i<=1;i++){
                   5064:           nbcode[Tvar[k]][++ij]=i;
                   5065:         }
                   5066:         break;
                   5067:        default:
                   5068:         break;
                   5069:        } /* end switch */
                   5070:      } /* end dummy test */
                   5071:     
                   5072:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5073:      /*        /\*recode from 0 *\/ */
                   5074:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5075:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5076:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5077:      /*        } */
                   5078:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5079:      /*        if (ij > ncodemax[j]) { */
                   5080:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5081:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5082:      /*          break; */
                   5083:      /*        } */
                   5084:      /*   }  /\* end of loop on modality k *\/ */
                   5085:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5086:   
                   5087:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5088:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5089:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5090:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5091:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5092:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5093:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5094:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5095:   
                   5096:    ij=0;
                   5097:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5098:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5099:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5100:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5101:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5102:        /* If product not in single variable we don't print results */
                   5103:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5104:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5105:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5106:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5107:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5108:        if(Fixed[k]!=0)
                   5109:         anyvaryingduminmodel=1;
                   5110:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5111:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5112:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5113:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5114:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5115:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5116:      } 
                   5117:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5118:    /* ij--; */
                   5119:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5120:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5121:                * because they can be excluded from the model and real
                   5122:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5123:    for(j=ij+1; j<= cptcovt; j++){
                   5124:      Tvaraff[j]=0;
                   5125:      Tmodelind[j]=0;
                   5126:    }
                   5127:    for(j=ntveff+1; j<= cptcovt; j++){
                   5128:      TmodelInvind[j]=0;
                   5129:    }
                   5130:    /* To be sorted */
                   5131:    ;
                   5132:  }
1.126     brouard  5133: 
1.145     brouard  5134: 
1.126     brouard  5135: /*********** Health Expectancies ****************/
                   5136: 
1.235     brouard  5137:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5138: 
                   5139: {
                   5140:   /* Health expectancies, no variances */
1.164     brouard  5141:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5142:   int nhstepma, nstepma; /* Decreasing with age */
                   5143:   double age, agelim, hf;
                   5144:   double ***p3mat;
                   5145:   double eip;
                   5146: 
1.238     brouard  5147:   /* pstamp(ficreseij); */
1.126     brouard  5148:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5149:   fprintf(ficreseij,"# Age");
                   5150:   for(i=1; i<=nlstate;i++){
                   5151:     for(j=1; j<=nlstate;j++){
                   5152:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5153:     }
                   5154:     fprintf(ficreseij," e%1d. ",i);
                   5155:   }
                   5156:   fprintf(ficreseij,"\n");
                   5157: 
                   5158:   
                   5159:   if(estepm < stepm){
                   5160:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5161:   }
                   5162:   else  hstepm=estepm;   
                   5163:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5164:    * This is mainly to measure the difference between two models: for example
                   5165:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5166:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5167:    * progression in between and thus overestimating or underestimating according
                   5168:    * to the curvature of the survival function. If, for the same date, we 
                   5169:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5170:    * to compare the new estimate of Life expectancy with the same linear 
                   5171:    * hypothesis. A more precise result, taking into account a more precise
                   5172:    * curvature will be obtained if estepm is as small as stepm. */
                   5173: 
                   5174:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5175:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5176:      nhstepm is the number of hstepm from age to agelim 
                   5177:      nstepm is the number of stepm from age to agelin. 
                   5178:      Look at hpijx to understand the reason of that which relies in memory size
                   5179:      and note for a fixed period like estepm months */
                   5180:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5181:      survival function given by stepm (the optimization length). Unfortunately it
                   5182:      means that if the survival funtion is printed only each two years of age and if
                   5183:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5184:      results. So we changed our mind and took the option of the best precision.
                   5185:   */
                   5186:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5187: 
                   5188:   agelim=AGESUP;
                   5189:   /* If stepm=6 months */
                   5190:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5191:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5192:     
                   5193: /* nhstepm age range expressed in number of stepm */
                   5194:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5195:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5196:   /* if (stepm >= YEARM) hstepm=1;*/
                   5197:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5198:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5199: 
                   5200:   for (age=bage; age<=fage; age ++){ 
                   5201:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5202:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5203:     /* if (stepm >= YEARM) hstepm=1;*/
                   5204:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5205: 
                   5206:     /* If stepm=6 months */
                   5207:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5208:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5209:     
1.235     brouard  5210:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5211:     
                   5212:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5213:     
                   5214:     printf("%d|",(int)age);fflush(stdout);
                   5215:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5216:     
                   5217:     /* Computing expectancies */
                   5218:     for(i=1; i<=nlstate;i++)
                   5219:       for(j=1; j<=nlstate;j++)
                   5220:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5221:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5222:          
                   5223:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5224: 
                   5225:        }
                   5226: 
                   5227:     fprintf(ficreseij,"%3.0f",age );
                   5228:     for(i=1; i<=nlstate;i++){
                   5229:       eip=0;
                   5230:       for(j=1; j<=nlstate;j++){
                   5231:        eip +=eij[i][j][(int)age];
                   5232:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5233:       }
                   5234:       fprintf(ficreseij,"%9.4f", eip );
                   5235:     }
                   5236:     fprintf(ficreseij,"\n");
                   5237:     
                   5238:   }
                   5239:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5240:   printf("\n");
                   5241:   fprintf(ficlog,"\n");
                   5242:   
                   5243: }
                   5244: 
1.235     brouard  5245:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5246: 
                   5247: {
                   5248:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5249:      to initial status i, ei. .
1.126     brouard  5250:   */
                   5251:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5252:   int nhstepma, nstepma; /* Decreasing with age */
                   5253:   double age, agelim, hf;
                   5254:   double ***p3matp, ***p3matm, ***varhe;
                   5255:   double **dnewm,**doldm;
                   5256:   double *xp, *xm;
                   5257:   double **gp, **gm;
                   5258:   double ***gradg, ***trgradg;
                   5259:   int theta;
                   5260: 
                   5261:   double eip, vip;
                   5262: 
                   5263:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5264:   xp=vector(1,npar);
                   5265:   xm=vector(1,npar);
                   5266:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5267:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5268:   
                   5269:   pstamp(ficresstdeij);
                   5270:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5271:   fprintf(ficresstdeij,"# Age");
                   5272:   for(i=1; i<=nlstate;i++){
                   5273:     for(j=1; j<=nlstate;j++)
                   5274:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5275:     fprintf(ficresstdeij," e%1d. ",i);
                   5276:   }
                   5277:   fprintf(ficresstdeij,"\n");
                   5278: 
                   5279:   pstamp(ficrescveij);
                   5280:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5281:   fprintf(ficrescveij,"# Age");
                   5282:   for(i=1; i<=nlstate;i++)
                   5283:     for(j=1; j<=nlstate;j++){
                   5284:       cptj= (j-1)*nlstate+i;
                   5285:       for(i2=1; i2<=nlstate;i2++)
                   5286:        for(j2=1; j2<=nlstate;j2++){
                   5287:          cptj2= (j2-1)*nlstate+i2;
                   5288:          if(cptj2 <= cptj)
                   5289:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5290:        }
                   5291:     }
                   5292:   fprintf(ficrescveij,"\n");
                   5293:   
                   5294:   if(estepm < stepm){
                   5295:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5296:   }
                   5297:   else  hstepm=estepm;   
                   5298:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5299:    * This is mainly to measure the difference between two models: for example
                   5300:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5301:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5302:    * progression in between and thus overestimating or underestimating according
                   5303:    * to the curvature of the survival function. If, for the same date, we 
                   5304:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5305:    * to compare the new estimate of Life expectancy with the same linear 
                   5306:    * hypothesis. A more precise result, taking into account a more precise
                   5307:    * curvature will be obtained if estepm is as small as stepm. */
                   5308: 
                   5309:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5310:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5311:      nhstepm is the number of hstepm from age to agelim 
                   5312:      nstepm is the number of stepm from age to agelin. 
                   5313:      Look at hpijx to understand the reason of that which relies in memory size
                   5314:      and note for a fixed period like estepm months */
                   5315:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5316:      survival function given by stepm (the optimization length). Unfortunately it
                   5317:      means that if the survival funtion is printed only each two years of age and if
                   5318:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5319:      results. So we changed our mind and took the option of the best precision.
                   5320:   */
                   5321:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5322: 
                   5323:   /* If stepm=6 months */
                   5324:   /* nhstepm age range expressed in number of stepm */
                   5325:   agelim=AGESUP;
                   5326:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5327:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5328:   /* if (stepm >= YEARM) hstepm=1;*/
                   5329:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5330:   
                   5331:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5332:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5333:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5334:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5335:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5336:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5337: 
                   5338:   for (age=bage; age<=fage; age ++){ 
                   5339:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5340:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5341:     /* if (stepm >= YEARM) hstepm=1;*/
                   5342:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5343:                
1.126     brouard  5344:     /* If stepm=6 months */
                   5345:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5346:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5347:     
                   5348:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5349:                
1.126     brouard  5350:     /* Computing  Variances of health expectancies */
                   5351:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5352:        decrease memory allocation */
                   5353:     for(theta=1; theta <=npar; theta++){
                   5354:       for(i=1; i<=npar; i++){ 
1.222     brouard  5355:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5356:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5357:       }
1.235     brouard  5358:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5359:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5360:                        
1.126     brouard  5361:       for(j=1; j<= nlstate; j++){
1.222     brouard  5362:        for(i=1; i<=nlstate; i++){
                   5363:          for(h=0; h<=nhstepm-1; h++){
                   5364:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5365:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5366:          }
                   5367:        }
1.126     brouard  5368:       }
1.218     brouard  5369:                        
1.126     brouard  5370:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5371:        for(h=0; h<=nhstepm-1; h++){
                   5372:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5373:        }
1.126     brouard  5374:     }/* End theta */
                   5375:     
                   5376:     
                   5377:     for(h=0; h<=nhstepm-1; h++)
                   5378:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5379:        for(theta=1; theta <=npar; theta++)
                   5380:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5381:     
1.218     brouard  5382:                
1.222     brouard  5383:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5384:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5385:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5386:                
1.222     brouard  5387:     printf("%d|",(int)age);fflush(stdout);
                   5388:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5389:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5390:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5391:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5392:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5393:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5394:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5395:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5396:       }
                   5397:     }
1.218     brouard  5398:                
1.126     brouard  5399:     /* Computing expectancies */
1.235     brouard  5400:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5401:     for(i=1; i<=nlstate;i++)
                   5402:       for(j=1; j<=nlstate;j++)
1.222     brouard  5403:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5404:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5405:                                        
1.222     brouard  5406:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5407:                                        
1.222     brouard  5408:        }
1.218     brouard  5409:                
1.126     brouard  5410:     fprintf(ficresstdeij,"%3.0f",age );
                   5411:     for(i=1; i<=nlstate;i++){
                   5412:       eip=0.;
                   5413:       vip=0.;
                   5414:       for(j=1; j<=nlstate;j++){
1.222     brouard  5415:        eip += eij[i][j][(int)age];
                   5416:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5417:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5418:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5419:       }
                   5420:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5421:     }
                   5422:     fprintf(ficresstdeij,"\n");
1.218     brouard  5423:                
1.126     brouard  5424:     fprintf(ficrescveij,"%3.0f",age );
                   5425:     for(i=1; i<=nlstate;i++)
                   5426:       for(j=1; j<=nlstate;j++){
1.222     brouard  5427:        cptj= (j-1)*nlstate+i;
                   5428:        for(i2=1; i2<=nlstate;i2++)
                   5429:          for(j2=1; j2<=nlstate;j2++){
                   5430:            cptj2= (j2-1)*nlstate+i2;
                   5431:            if(cptj2 <= cptj)
                   5432:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5433:          }
1.126     brouard  5434:       }
                   5435:     fprintf(ficrescveij,"\n");
1.218     brouard  5436:                
1.126     brouard  5437:   }
                   5438:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5439:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5440:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5441:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5442:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5443:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5444:   printf("\n");
                   5445:   fprintf(ficlog,"\n");
1.218     brouard  5446:        
1.126     brouard  5447:   free_vector(xm,1,npar);
                   5448:   free_vector(xp,1,npar);
                   5449:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5450:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5451:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5452: }
1.218     brouard  5453:  
1.126     brouard  5454: /************ Variance ******************/
1.235     brouard  5455:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5456:  {
                   5457:    /* Variance of health expectancies */
                   5458:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5459:    /* double **newm;*/
                   5460:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5461:   
                   5462:    /* int movingaverage(); */
                   5463:    double **dnewm,**doldm;
                   5464:    double **dnewmp,**doldmp;
                   5465:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5466:    int k;
                   5467:    double *xp;
                   5468:    double **gp, **gm;  /* for var eij */
                   5469:    double ***gradg, ***trgradg; /*for var eij */
                   5470:    double **gradgp, **trgradgp; /* for var p point j */
                   5471:    double *gpp, *gmp; /* for var p point j */
                   5472:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5473:    double ***p3mat;
                   5474:    double age,agelim, hf;
                   5475:    /* double ***mobaverage; */
                   5476:    int theta;
                   5477:    char digit[4];
                   5478:    char digitp[25];
                   5479: 
                   5480:    char fileresprobmorprev[FILENAMELENGTH];
                   5481: 
                   5482:    if(popbased==1){
                   5483:      if(mobilav!=0)
                   5484:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5485:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5486:    }
                   5487:    else 
                   5488:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5489: 
1.218     brouard  5490:    /* if (mobilav!=0) { */
                   5491:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5492:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5493:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5494:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5495:    /*   } */
                   5496:    /* } */
                   5497: 
                   5498:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5499:    sprintf(digit,"%-d",ij);
                   5500:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5501:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5502:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5503:    strcat(fileresprobmorprev,fileresu);
                   5504:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5505:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5506:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5507:    }
                   5508:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5509:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5510:    pstamp(ficresprobmorprev);
                   5511:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5512:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5513:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5514:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5515:    }
                   5516:    for(j=1;j<=cptcoveff;j++) 
                   5517:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5518:    fprintf(ficresprobmorprev,"\n");
                   5519: 
1.218     brouard  5520:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5521:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5522:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5523:      for(i=1; i<=nlstate;i++)
                   5524:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5525:    }  
                   5526:    fprintf(ficresprobmorprev,"\n");
                   5527:   
                   5528:    fprintf(ficgp,"\n# Routine varevsij");
                   5529:    fprintf(ficgp,"\nunset title \n");
                   5530:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5531:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5532:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5533:    /*   } */
                   5534:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5535:    pstamp(ficresvij);
                   5536:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5537:    if(popbased==1)
                   5538:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5539:    else
                   5540:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5541:    fprintf(ficresvij,"# Age");
                   5542:    for(i=1; i<=nlstate;i++)
                   5543:      for(j=1; j<=nlstate;j++)
                   5544:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5545:    fprintf(ficresvij,"\n");
                   5546: 
                   5547:    xp=vector(1,npar);
                   5548:    dnewm=matrix(1,nlstate,1,npar);
                   5549:    doldm=matrix(1,nlstate,1,nlstate);
                   5550:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5551:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5552: 
                   5553:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5554:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5555:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5556:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5557:   
1.218     brouard  5558:    if(estepm < stepm){
                   5559:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5560:    }
                   5561:    else  hstepm=estepm;   
                   5562:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5563:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5564:       nhstepm is the number of hstepm from age to agelim 
                   5565:       nstepm is the number of stepm from age to agelim. 
                   5566:       Look at function hpijx to understand why because of memory size limitations, 
                   5567:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5568:       survival function given by stepm (the optimization length). Unfortunately it
                   5569:       means that if the survival funtion is printed every two years of age and if
                   5570:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5571:       results. So we changed our mind and took the option of the best precision.
                   5572:    */
                   5573:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5574:    agelim = AGESUP;
                   5575:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5576:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5577:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5578:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5579:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5580:      gp=matrix(0,nhstepm,1,nlstate);
                   5581:      gm=matrix(0,nhstepm,1,nlstate);
                   5582:                
                   5583:                
                   5584:      for(theta=1; theta <=npar; theta++){
                   5585:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5586:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5587:        }
                   5588:                        
1.242     brouard  5589:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5590:                        
                   5591:        if (popbased==1) {
                   5592:         if(mobilav ==0){
                   5593:           for(i=1; i<=nlstate;i++)
                   5594:             prlim[i][i]=probs[(int)age][i][ij];
                   5595:         }else{ /* mobilav */ 
                   5596:           for(i=1; i<=nlstate;i++)
                   5597:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5598:         }
                   5599:        }
                   5600:                        
1.235     brouard  5601:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5602:        for(j=1; j<= nlstate; j++){
                   5603:         for(h=0; h<=nhstepm; h++){
                   5604:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5605:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5606:         }
                   5607:        }
                   5608:        /* Next for computing probability of death (h=1 means
                   5609:          computed over hstepm matrices product = hstepm*stepm months) 
                   5610:          as a weighted average of prlim.
                   5611:        */
                   5612:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5613:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5614:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5615:        }    
                   5616:        /* end probability of death */
                   5617:                        
                   5618:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5619:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5620:                        
1.242     brouard  5621:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5622:                        
                   5623:        if (popbased==1) {
                   5624:         if(mobilav ==0){
                   5625:           for(i=1; i<=nlstate;i++)
                   5626:             prlim[i][i]=probs[(int)age][i][ij];
                   5627:         }else{ /* mobilav */ 
                   5628:           for(i=1; i<=nlstate;i++)
                   5629:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5630:         }
                   5631:        }
                   5632:                        
1.235     brouard  5633:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5634:                        
                   5635:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5636:         for(h=0; h<=nhstepm; h++){
                   5637:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5638:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5639:         }
                   5640:        }
                   5641:        /* This for computing probability of death (h=1 means
                   5642:          computed over hstepm matrices product = hstepm*stepm months) 
                   5643:          as a weighted average of prlim.
                   5644:        */
                   5645:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5646:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5647:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5648:        }    
                   5649:        /* end probability of death */
                   5650:                        
                   5651:        for(j=1; j<= nlstate; j++) /* vareij */
                   5652:         for(h=0; h<=nhstepm; h++){
                   5653:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5654:         }
                   5655:                        
                   5656:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5657:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5658:        }
                   5659:                        
                   5660:      } /* End theta */
                   5661:                
                   5662:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5663:                
                   5664:      for(h=0; h<=nhstepm; h++) /* veij */
                   5665:        for(j=1; j<=nlstate;j++)
                   5666:         for(theta=1; theta <=npar; theta++)
                   5667:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5668:                
                   5669:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5670:        for(theta=1; theta <=npar; theta++)
                   5671:         trgradgp[j][theta]=gradgp[theta][j];
                   5672:                
                   5673:                
                   5674:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5675:      for(i=1;i<=nlstate;i++)
                   5676:        for(j=1;j<=nlstate;j++)
                   5677:         vareij[i][j][(int)age] =0.;
                   5678:                
                   5679:      for(h=0;h<=nhstepm;h++){
                   5680:        for(k=0;k<=nhstepm;k++){
                   5681:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5682:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5683:         for(i=1;i<=nlstate;i++)
                   5684:           for(j=1;j<=nlstate;j++)
                   5685:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5686:        }
                   5687:      }
                   5688:                
                   5689:      /* pptj */
                   5690:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5691:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5692:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5693:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5694:         varppt[j][i]=doldmp[j][i];
                   5695:      /* end ppptj */
                   5696:      /*  x centered again */
                   5697:                
1.242     brouard  5698:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5699:                
                   5700:      if (popbased==1) {
                   5701:        if(mobilav ==0){
                   5702:         for(i=1; i<=nlstate;i++)
                   5703:           prlim[i][i]=probs[(int)age][i][ij];
                   5704:        }else{ /* mobilav */ 
                   5705:         for(i=1; i<=nlstate;i++)
                   5706:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   5707:        }
                   5708:      }
                   5709:                
                   5710:      /* This for computing probability of death (h=1 means
                   5711:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   5712:        as a weighted average of prlim.
                   5713:      */
1.235     brouard  5714:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  5715:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5716:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   5717:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   5718:      }    
                   5719:      /* end probability of death */
                   5720:                
                   5721:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   5722:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5723:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   5724:        for(i=1; i<=nlstate;i++){
                   5725:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   5726:        }
                   5727:      } 
                   5728:      fprintf(ficresprobmorprev,"\n");
                   5729:                
                   5730:      fprintf(ficresvij,"%.0f ",age );
                   5731:      for(i=1; i<=nlstate;i++)
                   5732:        for(j=1; j<=nlstate;j++){
                   5733:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   5734:        }
                   5735:      fprintf(ficresvij,"\n");
                   5736:      free_matrix(gp,0,nhstepm,1,nlstate);
                   5737:      free_matrix(gm,0,nhstepm,1,nlstate);
                   5738:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   5739:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   5740:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5741:    } /* End age */
                   5742:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   5743:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   5744:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   5745:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   5746:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   5747:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   5748:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   5749:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   5750:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5751:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   5752:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5753:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5754:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   5755:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   5756:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   5757:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   5758:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5759:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  5760:     */
1.218     brouard  5761:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   5762:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  5763: 
1.218     brouard  5764:    free_vector(xp,1,npar);
                   5765:    free_matrix(doldm,1,nlstate,1,nlstate);
                   5766:    free_matrix(dnewm,1,nlstate,1,npar);
                   5767:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5768:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   5769:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5770:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5771:    fclose(ficresprobmorprev);
                   5772:    fflush(ficgp);
                   5773:    fflush(fichtm); 
                   5774:  }  /* end varevsij */
1.126     brouard  5775: 
                   5776: /************ Variance of prevlim ******************/
1.235     brouard  5777:  void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  5778: {
1.205     brouard  5779:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  5780:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  5781: 
1.126     brouard  5782:   double **dnewm,**doldm;
                   5783:   int i, j, nhstepm, hstepm;
                   5784:   double *xp;
                   5785:   double *gp, *gm;
                   5786:   double **gradg, **trgradg;
1.208     brouard  5787:   double **mgm, **mgp;
1.126     brouard  5788:   double age,agelim;
                   5789:   int theta;
                   5790:   
                   5791:   pstamp(ficresvpl);
                   5792:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  5793:   fprintf(ficresvpl,"# Age ");
                   5794:   if(nresult >=1)
                   5795:     fprintf(ficresvpl," Result# ");
1.126     brouard  5796:   for(i=1; i<=nlstate;i++)
                   5797:       fprintf(ficresvpl," %1d-%1d",i,i);
                   5798:   fprintf(ficresvpl,"\n");
                   5799: 
                   5800:   xp=vector(1,npar);
                   5801:   dnewm=matrix(1,nlstate,1,npar);
                   5802:   doldm=matrix(1,nlstate,1,nlstate);
                   5803:   
                   5804:   hstepm=1*YEARM; /* Every year of age */
                   5805:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   5806:   agelim = AGESUP;
                   5807:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5808:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5809:     if (stepm >= YEARM) hstepm=1;
                   5810:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   5811:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  5812:     mgp=matrix(1,npar,1,nlstate);
                   5813:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  5814:     gp=vector(1,nlstate);
                   5815:     gm=vector(1,nlstate);
                   5816: 
                   5817:     for(theta=1; theta <=npar; theta++){
                   5818:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   5819:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5820:       }
1.209     brouard  5821:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5822:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5823:       else
1.235     brouard  5824:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5825:       for(i=1;i<=nlstate;i++){
1.126     brouard  5826:        gp[i] = prlim[i][i];
1.208     brouard  5827:        mgp[theta][i] = prlim[i][i];
                   5828:       }
1.126     brouard  5829:       for(i=1; i<=npar; i++) /* Computes gradient */
                   5830:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  5831:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5832:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5833:       else
1.235     brouard  5834:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5835:       for(i=1;i<=nlstate;i++){
1.126     brouard  5836:        gm[i] = prlim[i][i];
1.208     brouard  5837:        mgm[theta][i] = prlim[i][i];
                   5838:       }
1.126     brouard  5839:       for(i=1;i<=nlstate;i++)
                   5840:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  5841:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  5842:     } /* End theta */
                   5843: 
                   5844:     trgradg =matrix(1,nlstate,1,npar);
                   5845: 
                   5846:     for(j=1; j<=nlstate;j++)
                   5847:       for(theta=1; theta <=npar; theta++)
                   5848:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  5849:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5850:     /*   printf("\nmgm mgp %d ",(int)age); */
                   5851:     /*   for(j=1; j<=nlstate;j++){ */
                   5852:     /*         printf(" %d ",j); */
                   5853:     /*         for(theta=1; theta <=npar; theta++) */
                   5854:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   5855:     /*         printf("\n "); */
                   5856:     /*   } */
                   5857:     /* } */
                   5858:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5859:     /*   printf("\n gradg %d ",(int)age); */
                   5860:     /*   for(j=1; j<=nlstate;j++){ */
                   5861:     /*         printf("%d ",j); */
                   5862:     /*         for(theta=1; theta <=npar; theta++) */
                   5863:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   5864:     /*         printf("\n "); */
                   5865:     /*   } */
                   5866:     /* } */
1.126     brouard  5867: 
                   5868:     for(i=1;i<=nlstate;i++)
                   5869:       varpl[i][(int)age] =0.;
1.209     brouard  5870:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.205     brouard  5871:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   5872:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
                   5873:     }else{
1.126     brouard  5874:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   5875:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  5876:     }
1.126     brouard  5877:     for(i=1;i<=nlstate;i++)
                   5878:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   5879: 
                   5880:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  5881:     if(nresult >=1)
                   5882:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  5883:     for(i=1; i<=nlstate;i++)
                   5884:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   5885:     fprintf(ficresvpl,"\n");
                   5886:     free_vector(gp,1,nlstate);
                   5887:     free_vector(gm,1,nlstate);
1.208     brouard  5888:     free_matrix(mgm,1,npar,1,nlstate);
                   5889:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  5890:     free_matrix(gradg,1,npar,1,nlstate);
                   5891:     free_matrix(trgradg,1,nlstate,1,npar);
                   5892:   } /* End age */
                   5893: 
                   5894:   free_vector(xp,1,npar);
                   5895:   free_matrix(doldm,1,nlstate,1,npar);
                   5896:   free_matrix(dnewm,1,nlstate,1,nlstate);
                   5897: 
                   5898: }
                   5899: 
                   5900: /************ Variance of one-step probabilities  ******************/
                   5901: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  5902:  {
                   5903:    int i, j=0,  k1, l1, tj;
                   5904:    int k2, l2, j1,  z1;
                   5905:    int k=0, l;
                   5906:    int first=1, first1, first2;
                   5907:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   5908:    double **dnewm,**doldm;
                   5909:    double *xp;
                   5910:    double *gp, *gm;
                   5911:    double **gradg, **trgradg;
                   5912:    double **mu;
                   5913:    double age, cov[NCOVMAX+1];
                   5914:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   5915:    int theta;
                   5916:    char fileresprob[FILENAMELENGTH];
                   5917:    char fileresprobcov[FILENAMELENGTH];
                   5918:    char fileresprobcor[FILENAMELENGTH];
                   5919:    double ***varpij;
                   5920: 
                   5921:    strcpy(fileresprob,"PROB_"); 
                   5922:    strcat(fileresprob,fileres);
                   5923:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   5924:      printf("Problem with resultfile: %s\n", fileresprob);
                   5925:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   5926:    }
                   5927:    strcpy(fileresprobcov,"PROBCOV_"); 
                   5928:    strcat(fileresprobcov,fileresu);
                   5929:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   5930:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   5931:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   5932:    }
                   5933:    strcpy(fileresprobcor,"PROBCOR_"); 
                   5934:    strcat(fileresprobcor,fileresu);
                   5935:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   5936:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   5937:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   5938:    }
                   5939:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   5940:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   5941:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   5942:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   5943:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   5944:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   5945:    pstamp(ficresprob);
                   5946:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   5947:    fprintf(ficresprob,"# Age");
                   5948:    pstamp(ficresprobcov);
                   5949:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   5950:    fprintf(ficresprobcov,"# Age");
                   5951:    pstamp(ficresprobcor);
                   5952:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   5953:    fprintf(ficresprobcor,"# Age");
1.126     brouard  5954: 
                   5955: 
1.222     brouard  5956:    for(i=1; i<=nlstate;i++)
                   5957:      for(j=1; j<=(nlstate+ndeath);j++){
                   5958:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   5959:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   5960:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   5961:      }  
                   5962:    /* fprintf(ficresprob,"\n");
                   5963:       fprintf(ficresprobcov,"\n");
                   5964:       fprintf(ficresprobcor,"\n");
                   5965:    */
                   5966:    xp=vector(1,npar);
                   5967:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   5968:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   5969:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   5970:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   5971:    first=1;
                   5972:    fprintf(ficgp,"\n# Routine varprob");
                   5973:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   5974:    fprintf(fichtm,"\n");
                   5975: 
                   5976:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.</li>\n",optionfilehtmcov);
                   5977:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   5978:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  5979: and drawn. It helps understanding how is the covariance between two incidences.\
                   5980:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  5981:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  5982: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   5983: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   5984: standard deviations wide on each axis. <br>\
                   5985:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   5986:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   5987: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   5988: 
1.222     brouard  5989:    cov[1]=1;
                   5990:    /* tj=cptcoveff; */
1.225     brouard  5991:    tj = (int) pow(2,cptcoveff);
1.222     brouard  5992:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   5993:    j1=0;
1.224     brouard  5994:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  5995:      if  (cptcovn>0) {
                   5996:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  5997:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5998:        fprintf(ficresprob, "**********\n#\n");
                   5999:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6000:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6001:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6002:                        
1.222     brouard  6003:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6004:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6005:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6006:                        
                   6007:                        
1.222     brouard  6008:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6009:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6010:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6011:                        
1.222     brouard  6012:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6013:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6014:        fprintf(ficresprobcor, "**********\n#");    
                   6015:        if(invalidvarcomb[j1]){
                   6016:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6017:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6018:         continue;
                   6019:        }
                   6020:      }
                   6021:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6022:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6023:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6024:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6025:      for (age=bage; age<=fage; age ++){ 
                   6026:        cov[2]=age;
                   6027:        if(nagesqr==1)
                   6028:         cov[3]= age*age;
                   6029:        for (k=1; k<=cptcovn;k++) {
                   6030:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6031:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6032:                                                                    * 1  1 1 1 1
                   6033:                                                                    * 2  2 1 1 1
                   6034:                                                                    * 3  1 2 1 1
                   6035:                                                                    */
                   6036:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6037:        }
                   6038:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6039:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6040:        for (k=1; k<=cptcovprod;k++)
                   6041:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6042:                        
                   6043:                        
1.222     brouard  6044:        for(theta=1; theta <=npar; theta++){
                   6045:         for(i=1; i<=npar; i++)
                   6046:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6047:                                
1.222     brouard  6048:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6049:                                
1.222     brouard  6050:         k=0;
                   6051:         for(i=1; i<= (nlstate); i++){
                   6052:           for(j=1; j<=(nlstate+ndeath);j++){
                   6053:             k=k+1;
                   6054:             gp[k]=pmmij[i][j];
                   6055:           }
                   6056:         }
1.220     brouard  6057:                                
1.222     brouard  6058:         for(i=1; i<=npar; i++)
                   6059:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6060:                                
1.222     brouard  6061:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6062:         k=0;
                   6063:         for(i=1; i<=(nlstate); i++){
                   6064:           for(j=1; j<=(nlstate+ndeath);j++){
                   6065:             k=k+1;
                   6066:             gm[k]=pmmij[i][j];
                   6067:           }
                   6068:         }
1.220     brouard  6069:                                
1.222     brouard  6070:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6071:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6072:        }
1.126     brouard  6073: 
1.222     brouard  6074:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6075:         for(theta=1; theta <=npar; theta++)
                   6076:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6077:                        
1.222     brouard  6078:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6079:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6080:                        
1.222     brouard  6081:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6082:                        
1.222     brouard  6083:        k=0;
                   6084:        for(i=1; i<=(nlstate); i++){
                   6085:         for(j=1; j<=(nlstate+ndeath);j++){
                   6086:           k=k+1;
                   6087:           mu[k][(int) age]=pmmij[i][j];
                   6088:         }
                   6089:        }
                   6090:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6091:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6092:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6093:                        
1.222     brouard  6094:        /*printf("\n%d ",(int)age);
                   6095:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6096:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6097:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6098:         }*/
1.220     brouard  6099:                        
1.222     brouard  6100:        fprintf(ficresprob,"\n%d ",(int)age);
                   6101:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6102:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6103:                        
1.222     brouard  6104:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6105:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6106:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6107:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6108:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6109:        }
                   6110:        i=0;
                   6111:        for (k=1; k<=(nlstate);k++){
                   6112:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6113:           i++;
                   6114:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6115:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6116:           for (j=1; j<=i;j++){
                   6117:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6118:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6119:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6120:           }
                   6121:         }
                   6122:        }/* end of loop for state */
                   6123:      } /* end of loop for age */
                   6124:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6125:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6126:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6127:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6128:     
                   6129:      /* Confidence intervalle of pij  */
                   6130:      /*
                   6131:        fprintf(ficgp,"\nunset parametric;unset label");
                   6132:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6133:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6134:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6135:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6136:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6137:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6138:      */
                   6139:                
                   6140:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6141:      first1=1;first2=2;
                   6142:      for (k2=1; k2<=(nlstate);k2++){
                   6143:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6144:         if(l2==k2) continue;
                   6145:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6146:         for (k1=1; k1<=(nlstate);k1++){
                   6147:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6148:             if(l1==k1) continue;
                   6149:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6150:             if(i<=j) continue;
                   6151:             for (age=bage; age<=fage; age ++){ 
                   6152:               if ((int)age %5==0){
                   6153:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6154:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6155:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6156:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6157:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6158:                 c12=cv12/sqrt(v1*v2);
                   6159:                 /* Computing eigen value of matrix of covariance */
                   6160:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6161:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6162:                 if ((lc2 <0) || (lc1 <0) ){
                   6163:                   if(first2==1){
                   6164:                     first1=0;
                   6165:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6166:                   }
                   6167:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6168:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6169:                   /* lc2=fabs(lc2); */
                   6170:                 }
1.220     brouard  6171:                                                                
1.222     brouard  6172:                 /* Eigen vectors */
                   6173:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   6174:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6175:                 v21=(lc1-v1)/cv12*v11;
                   6176:                 v12=-v21;
                   6177:                 v22=v11;
                   6178:                 tnalp=v21/v11;
                   6179:                 if(first1==1){
                   6180:                   first1=0;
                   6181:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6182:                 }
                   6183:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6184:                 /*printf(fignu*/
                   6185:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6186:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6187:                 if(first==1){
                   6188:                   first=0;
                   6189:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6190:                   fprintf(ficgp,"\nset parametric;unset label");
                   6191:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6192:                   fprintf(ficgp,"\nset ter svg size 640, 480");
                   6193:                   fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6194:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6195: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6196:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6197:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6198:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6199:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6200:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6201:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6202:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6203:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
                   6204:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                                                         \
                   6205:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6206:                 }else{
                   6207:                   first=0;
                   6208:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6209:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6210:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6211:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
                   6212:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                 \
                   6213:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6214:                 }/* if first */
                   6215:               } /* age mod 5 */
                   6216:             } /* end loop age */
                   6217:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6218:             first=1;
                   6219:           } /*l12 */
                   6220:         } /* k12 */
                   6221:        } /*l1 */
                   6222:      }/* k1 */
                   6223:    }  /* loop on combination of covariates j1 */
                   6224:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6225:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6226:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6227:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6228:    free_vector(xp,1,npar);
                   6229:    fclose(ficresprob);
                   6230:    fclose(ficresprobcov);
                   6231:    fclose(ficresprobcor);
                   6232:    fflush(ficgp);
                   6233:    fflush(fichtmcov);
                   6234:  }
1.126     brouard  6235: 
                   6236: 
                   6237: /******************* Printing html file ***********/
1.201     brouard  6238: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6239:                  int lastpass, int stepm, int weightopt, char model[],\
                   6240:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.217     brouard  6241:                  int popforecast, int prevfcast, int backcast, int estepm , \
1.213     brouard  6242:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   6243:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.237     brouard  6244:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6245: 
                   6246:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6247:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6248: </ul>");
1.237     brouard  6249:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6250: </ul>", model);
1.214     brouard  6251:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6252:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6253:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6254:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6255:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6256:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6257:    fprintf(fichtm,"\
                   6258:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6259:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6260:    fprintf(fichtm,"\
1.217     brouard  6261:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6262:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6263:    fprintf(fichtm,"\
1.126     brouard  6264:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6265:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6266:    fprintf(fichtm,"\
1.217     brouard  6267:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6268:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6269:    fprintf(fichtm,"\
1.211     brouard  6270:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6271:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6272:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6273:    if(prevfcast==1){
                   6274:      fprintf(fichtm,"\
                   6275:  - Prevalence projections by age and states:                           \
1.201     brouard  6276:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6277:    }
1.126     brouard  6278: 
1.222     brouard  6279:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
1.126     brouard  6280: 
1.225     brouard  6281:    m=pow(2,cptcoveff);
1.222     brouard  6282:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6283: 
1.222     brouard  6284:    jj1=0;
1.237     brouard  6285: 
                   6286:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6287:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.237     brouard  6288:      if(TKresult[nres]!= k1)
                   6289:        continue;
1.220     brouard  6290: 
1.222     brouard  6291:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6292:      jj1++;
                   6293:      if (cptcovn > 0) {
                   6294:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6295:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6296:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6297:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6298:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6299:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6300:        }
1.237     brouard  6301:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6302:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6303:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6304:       }
                   6305:        
1.230     brouard  6306:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6307:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6308:        if(invalidvarcomb[k1]){
                   6309:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6310:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6311:         continue;
                   6312:        }
                   6313:      }
                   6314:      /* aij, bij */
1.241     brouard  6315:      fprintf(fichtm,"<br>- Logit model (yours is: 1+age+%s), for example: logit(pij)=log(pij/pii)= aij+ bij age + V1 age + etc. as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
                   6316: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6317:      /* Pij */
1.241     brouard  6318:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6319: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6320:      /* Quasi-incidences */
                   6321:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6322:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6323:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6324: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6325: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6326:      /* Survival functions (period) in state j */
                   6327:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6328:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6329: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6330:      }
                   6331:      /* State specific survival functions (period) */
                   6332:      for(cpt=1; cpt<=nlstate;cpt++){
                   6333:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6334:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.241     brouard  6335:  <a href=\"%s_%d-%d-%d.svg\">%s_%d%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6336:      }
                   6337:      /* Period (stable) prevalence in each health state */
                   6338:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6339:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6340: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6341:      }
                   6342:      if(backcast==1){
                   6343:        /* Period (stable) back prevalence in each health state */
                   6344:        for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6345:         fprintf(fichtm,"<br>\n- Convergence to period (stable) back prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6346: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6347:        }
1.217     brouard  6348:      }
1.222     brouard  6349:      if(prevfcast==1){
                   6350:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6351:        for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6352:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f) up to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6353: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6354:        }
                   6355:      }
1.220     brouard  6356:         
1.222     brouard  6357:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6358:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6359: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6360:      }
                   6361:      /* } /\* end i1 *\/ */
                   6362:    }/* End k1 */
                   6363:    fprintf(fichtm,"</ul>");
1.126     brouard  6364: 
1.222     brouard  6365:    fprintf(fichtm,"\
1.126     brouard  6366: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6367:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6368:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6369: But because parameters are usually highly correlated (a higher incidence of disability \
                   6370: and a higher incidence of recovery can give very close observed transition) it might \
                   6371: be very useful to look not only at linear confidence intervals estimated from the \
                   6372: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6373: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6374: covariance matrix of the one-step probabilities. \
                   6375: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6376: 
1.222     brouard  6377:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6378:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6379:    fprintf(fichtm,"\
1.126     brouard  6380:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6381:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6382: 
1.222     brouard  6383:    fprintf(fichtm,"\
1.126     brouard  6384:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6385:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6386:    fprintf(fichtm,"\
1.126     brouard  6387:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6388:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6389:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6390:    fprintf(fichtm,"\
1.126     brouard  6391:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6392:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6393:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6394:    fprintf(fichtm,"\
1.128     brouard  6395:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6396:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6397:    fprintf(fichtm,"\
1.128     brouard  6398:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6399:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6400:    fprintf(fichtm,"\
1.126     brouard  6401:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6402:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6403: 
                   6404: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6405: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6406: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6407: /*     <br>",fileres,fileres,fileres,fileres); */
                   6408: /*  else  */
                   6409: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6410:    fflush(fichtm);
                   6411:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6412: 
1.225     brouard  6413:    m=pow(2,cptcoveff);
1.222     brouard  6414:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6415: 
1.222     brouard  6416:    jj1=0;
1.237     brouard  6417: 
1.241     brouard  6418:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6419:    for(k1=1; k1<=m;k1++){
1.237     brouard  6420:      if(TKresult[nres]!= k1)
                   6421:        continue;
1.222     brouard  6422:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6423:      jj1++;
1.126     brouard  6424:      if (cptcovn > 0) {
                   6425:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6426:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6427:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6428:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6429:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6430:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6431:       }
                   6432: 
1.126     brouard  6433:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6434: 
1.222     brouard  6435:        if(invalidvarcomb[k1]){
                   6436:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6437:         continue;
                   6438:        }
1.126     brouard  6439:      }
                   6440:      for(cpt=1; cpt<=nlstate;cpt++) {
1.218     brouard  6441:        fprintf(fichtm,"\n<br>- Observed (cross-sectional) and period (incidence based) \
1.241     brouard  6442: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
                   6443: <img src=\"%s_%d-%d-%d.svg\">",cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  6444:      }
                   6445:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6446: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6447: true period expectancies (those weighted with period prevalences are also\
                   6448:  drawn in addition to the population based expectancies computed using\
1.241     brouard  6449:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   6450: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  6451:      /* } /\* end i1 *\/ */
                   6452:    }/* End k1 */
1.241     brouard  6453:   }/* End nres */
1.222     brouard  6454:    fprintf(fichtm,"</ul>");
                   6455:    fflush(fichtm);
1.126     brouard  6456: }
                   6457: 
                   6458: /******************* Gnuplot file **************/
1.223     brouard  6459: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[]){
1.126     brouard  6460: 
                   6461:   char dirfileres[132],optfileres[132];
1.223     brouard  6462:   char gplotcondition[132];
1.237     brouard  6463:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6464:   int lv=0, vlv=0, kl=0;
1.130     brouard  6465:   int ng=0;
1.201     brouard  6466:   int vpopbased;
1.223     brouard  6467:   int ioffset; /* variable offset for columns */
1.235     brouard  6468:   int nres=0; /* Index of resultline */
1.219     brouard  6469: 
1.126     brouard  6470: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6471: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6472: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6473: /*   } */
                   6474: 
                   6475:   /*#ifdef windows */
                   6476:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6477:   /*#endif */
1.225     brouard  6478:   m=pow(2,cptcoveff);
1.126     brouard  6479: 
1.202     brouard  6480:   /* Contribution to likelihood */
                   6481:   /* Plot the probability implied in the likelihood */
1.223     brouard  6482:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6483:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6484:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6485:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6486: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6487:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6488: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6489:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6490:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6491:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6492:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6493:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6494:   for (i=1; i<= nlstate ; i ++) {
                   6495:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6496:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6497:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6498:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6499:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6500:     }
                   6501:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6502:   }
                   6503:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6504:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6505:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6506:   fprintf(ficgp,"\nset out;unset log\n");
                   6507:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6508: 
1.126     brouard  6509:   strcpy(dirfileres,optionfilefiname);
                   6510:   strcpy(optfileres,"vpl");
1.223     brouard  6511:   /* 1eme*/
1.238     brouard  6512:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   6513:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  6514:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  6515:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
                   6516:        if(TKresult[nres]!= k1)
                   6517:          continue;
                   6518:        /* We are interested in selected combination by the resultline */
1.246     brouard  6519:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  6520:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
                   6521:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6522:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   6523:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6524:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6525:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6526:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   6527:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  6528:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  6529:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6530:        }
                   6531:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  6532:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  6533:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6534:        }       
1.246     brouard  6535:        /* printf("\n#\n"); */
1.238     brouard  6536:        fprintf(ficgp,"\n#\n");
                   6537:        if(invalidvarcomb[k1]){
                   6538:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6539:          continue;
                   6540:        }
1.235     brouard  6541:       
1.241     brouard  6542:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   6543:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
                   6544:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres);
1.235     brouard  6545:       
1.238     brouard  6546:        for (i=1; i<= nlstate ; i ++) {
                   6547:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6548:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   6549:        }
1.242     brouard  6550:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres);
1.238     brouard  6551:        for (i=1; i<= nlstate ; i ++) {
                   6552:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6553:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6554:        } 
1.242     brouard  6555:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); 
1.238     brouard  6556:        for (i=1; i<= nlstate ; i ++) {
                   6557:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6558:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6559:        }  
                   6560:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1));
                   6561:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   6562:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  6563:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  6564:          if(cptcoveff ==0){
1.245     brouard  6565:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  6566:          }else{
                   6567:            kl=0;
                   6568:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   6569:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6570:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6571:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6572:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6573:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  6574:              kl++;
1.238     brouard  6575:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6576:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6577:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6578:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6579:              if(k==cptcoveff){
1.245     brouard  6580:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  6581:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  6582:              }else{
                   6583:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   6584:                kl++;
                   6585:              }
                   6586:            } /* end covariate */
                   6587:          } /* end if no covariate */
                   6588:        } /* end if backcast */
                   6589:        fprintf(ficgp,"\nset out \n");
                   6590:       } /* nres */
1.201     brouard  6591:     } /* k1 */
                   6592:   } /* cpt */
1.235     brouard  6593: 
                   6594:   
1.126     brouard  6595:   /*2 eme*/
1.238     brouard  6596:   for (k1=1; k1<= m ; k1 ++){  
                   6597:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6598:       if(TKresult[nres]!= k1)
                   6599:        continue;
                   6600:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
                   6601:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  6602:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6603:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6604:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6605:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6606:        vlv= nbcode[Tvaraff[k]][lv];
                   6607:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6608:       }
1.237     brouard  6609:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  6610:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  6611:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  6612:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  6613:       }
1.211     brouard  6614:       fprintf(ficgp,"\n#\n");
1.223     brouard  6615:       if(invalidvarcomb[k1]){
                   6616:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6617:        continue;
                   6618:       }
1.219     brouard  6619:                        
1.241     brouard  6620:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  6621:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
                   6622:        if(vpopbased==0)
                   6623:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
                   6624:        else
                   6625:          fprintf(ficgp,"\nreplot ");
                   6626:        for (i=1; i<= nlstate+1 ; i ++) {
                   6627:          k=2*i;
                   6628:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1, vpopbased);
                   6629:          for (j=1; j<= nlstate+1 ; j ++) {
                   6630:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6631:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6632:          }   
                   6633:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   6634:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
                   6635:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6636:          for (j=1; j<= nlstate+1 ; j ++) {
                   6637:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6638:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6639:          }   
                   6640:          fprintf(ficgp,"\" t\"\" w l lt 0,");
                   6641:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6642:          for (j=1; j<= nlstate+1 ; j ++) {
                   6643:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6644:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6645:          }   
                   6646:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   6647:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   6648:        } /* state */
                   6649:       } /* vpopbased */
1.244     brouard  6650:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  6651:     } /* end nres */
                   6652:   } /* k1 end 2 eme*/
                   6653:        
                   6654:        
                   6655:   /*3eme*/
                   6656:   for (k1=1; k1<= m ; k1 ++){
                   6657:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.240     brouard  6658:       if(TKresult[nres]!= k1)
1.238     brouard  6659:        continue;
                   6660: 
                   6661:       for (cpt=1; cpt<= nlstate ; cpt ++) {
                   6662:        fprintf(ficgp,"\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
                   6663:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6664:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6665:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6666:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6667:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6668:          vlv= nbcode[Tvaraff[k]][lv];
                   6669:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6670:        }
                   6671:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6672:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6673:        }       
                   6674:        fprintf(ficgp,"\n#\n");
                   6675:        if(invalidvarcomb[k1]){
                   6676:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6677:          continue;
                   6678:        }
                   6679:                        
                   6680:        /*       k=2+nlstate*(2*cpt-2); */
                   6681:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  6682:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.238     brouard  6683:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.201     brouard  6684: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),k1-1,k1-1,k,cpt);
1.238     brouard  6685:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6686:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6687:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   6688:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6689:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6690:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  6691:                                
1.238     brouard  6692:        */
                   6693:        for (i=1; i< nlstate ; i ++) {
                   6694:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+i,cpt,i+1);
                   6695:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  6696:                                
1.238     brouard  6697:        } 
                   6698:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+nlstate,cpt);
                   6699:       }
                   6700:     } /* end nres */
                   6701:   } /* end kl 3eme */
1.126     brouard  6702:   
1.223     brouard  6703:   /* 4eme */
1.201     brouard  6704:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  6705:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   6706:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6707:       if(TKresult[nres]!= k1)
1.223     brouard  6708:        continue;
1.238     brouard  6709:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
                   6710:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   6711:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6712:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6713:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6714:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6715:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6716:          vlv= nbcode[Tvaraff[k]][lv];
                   6717:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6718:        }
                   6719:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6720:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6721:        }       
                   6722:        fprintf(ficgp,"\n#\n");
                   6723:        if(invalidvarcomb[k1]){
                   6724:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6725:          continue;
1.223     brouard  6726:        }
1.238     brouard  6727:       
1.241     brouard  6728:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.238     brouard  6729:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6730: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6731:        k=3;
                   6732:        for (i=1; i<= nlstate ; i ++){
                   6733:          if(i==1){
                   6734:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6735:          }else{
                   6736:            fprintf(ficgp,", '' ");
                   6737:          }
                   6738:          l=(nlstate+ndeath)*(i-1)+1;
                   6739:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6740:          for (j=2; j<= nlstate+ndeath ; j ++)
                   6741:            fprintf(ficgp,"+$%d",k+l+j-1);
                   6742:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   6743:        } /* nlstate */
                   6744:        fprintf(ficgp,"\nset out\n");
                   6745:       } /* end cpt state*/ 
                   6746:     } /* end nres */
                   6747:   } /* end covariate k1 */  
                   6748: 
1.220     brouard  6749: /* 5eme */
1.201     brouard  6750:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  6751:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   6752:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6753:       if(TKresult[nres]!= k1)
1.227     brouard  6754:        continue;
1.238     brouard  6755:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
                   6756:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   6757:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6758:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6759:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6760:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6761:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6762:          vlv= nbcode[Tvaraff[k]][lv];
                   6763:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6764:        }
                   6765:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6766:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6767:        }       
                   6768:        fprintf(ficgp,"\n#\n");
                   6769:        if(invalidvarcomb[k1]){
                   6770:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6771:          continue;
                   6772:        }
1.227     brouard  6773:       
1.241     brouard  6774:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.238     brouard  6775:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6776: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6777:        k=3;
                   6778:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6779:          if(j==1)
                   6780:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6781:          else
                   6782:            fprintf(ficgp,", '' ");
                   6783:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6784:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   6785:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   6786:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   6787:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   6788:        } /* nlstate */
                   6789:        fprintf(ficgp,", '' ");
                   6790:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   6791:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6792:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6793:          if(j < nlstate)
                   6794:            fprintf(ficgp,"$%d +",k+l);
                   6795:          else
                   6796:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   6797:        }
                   6798:        fprintf(ficgp,"\nset out\n");
                   6799:       } /* end cpt state*/ 
                   6800:     } /* end covariate */  
                   6801:   } /* end nres */
1.227     brouard  6802:   
1.220     brouard  6803: /* 6eme */
1.202     brouard  6804:   /* CV preval stable (period) for each covariate */
1.237     brouard  6805:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6806:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6807:     if(TKresult[nres]!= k1)
                   6808:       continue;
1.153     brouard  6809:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6810:       
1.211     brouard  6811:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  6812:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  6813:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6814:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6815:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6816:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6817:        vlv= nbcode[Tvaraff[k]][lv];
                   6818:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6819:       }
1.237     brouard  6820:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6821:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6822:       }        
1.211     brouard  6823:       fprintf(ficgp,"\n#\n");
1.223     brouard  6824:       if(invalidvarcomb[k1]){
1.227     brouard  6825:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6826:        continue;
1.223     brouard  6827:       }
1.227     brouard  6828:       
1.241     brouard  6829:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.126     brouard  6830:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  6831: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6832:       k=3; /* Offset */
1.153     brouard  6833:       for (i=1; i<= nlstate ; i ++){
1.227     brouard  6834:        if(i==1)
                   6835:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6836:        else
                   6837:          fprintf(ficgp,", '' ");
                   6838:        l=(nlstate+ndeath)*(i-1)+1;
                   6839:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6840:        for (j=2; j<= nlstate ; j ++)
                   6841:          fprintf(ficgp,"+$%d",k+l+j-1);
                   6842:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  6843:       } /* nlstate */
1.201     brouard  6844:       fprintf(ficgp,"\nset out\n");
1.153     brouard  6845:     } /* end cpt state*/ 
                   6846:   } /* end covariate */  
1.227     brouard  6847:   
                   6848:   
1.220     brouard  6849: /* 7eme */
1.218     brouard  6850:   if(backcast == 1){
1.217     brouard  6851:     /* CV back preval stable (period) for each covariate */
1.237     brouard  6852:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6853:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6854:       if(TKresult[nres]!= k1)
                   6855:        continue;
1.218     brouard  6856:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6857:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
                   6858:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6859:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6860:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6861:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  6862:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  6863:          vlv= nbcode[Tvaraff[k]][lv];
                   6864:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6865:        }
1.237     brouard  6866:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6867:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6868:        }       
1.227     brouard  6869:        fprintf(ficgp,"\n#\n");
                   6870:        if(invalidvarcomb[k1]){
                   6871:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6872:          continue;
                   6873:        }
                   6874:        
1.241     brouard  6875:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.227     brouard  6876:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  6877: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  6878:        k=3; /* Offset */
                   6879:        for (i=1; i<= nlstate ; i ++){
                   6880:          if(i==1)
                   6881:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   6882:          else
                   6883:            fprintf(ficgp,", '' ");
                   6884:          /* l=(nlstate+ndeath)*(i-1)+1; */
                   6885:          l=(nlstate+ndeath)*(cpt-1)+1;
                   6886:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   6887:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
                   6888:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+(cpt-1)+i-1); /* a vérifier */
                   6889:          /* for (j=2; j<= nlstate ; j ++) */
                   6890:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   6891:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
                   6892:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",i,cpt);
                   6893:        } /* nlstate */
                   6894:        fprintf(ficgp,"\nset out\n");
1.218     brouard  6895:       } /* end cpt state*/ 
                   6896:     } /* end covariate */  
                   6897:   } /* End if backcast */
                   6898:   
1.223     brouard  6899:   /* 8eme */
1.218     brouard  6900:   if(prevfcast==1){
                   6901:     /* Projection from cross-sectional to stable (period) for each covariate */
                   6902:     
1.237     brouard  6903:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6904:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6905:       if(TKresult[nres]!= k1)
                   6906:        continue;
1.211     brouard  6907:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6908:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   6909:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   6910:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6911:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6912:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6913:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6914:          vlv= nbcode[Tvaraff[k]][lv];
                   6915:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6916:        }
1.237     brouard  6917:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6918:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6919:        }       
1.227     brouard  6920:        fprintf(ficgp,"\n#\n");
                   6921:        if(invalidvarcomb[k1]){
                   6922:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6923:          continue;
                   6924:        }
                   6925:        
                   6926:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  6927:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.227     brouard  6928:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  6929: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  6930:        for (i=1; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   6931:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6932:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   6933:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6934:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   6935:          if(i==1){
                   6936:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   6937:          }else{
                   6938:            fprintf(ficgp,",\\\n '' ");
                   6939:          }
                   6940:          if(cptcoveff ==0){ /* No covariate */
                   6941:            ioffset=2; /* Age is in 2 */
                   6942:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   6943:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   6944:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   6945:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   6946:            fprintf(ficgp," u %d:(", ioffset); 
                   6947:            if(i==nlstate+1)
                   6948:              fprintf(ficgp," $%d/(1.-$%d)) t 'pw.%d' with line ",      \
                   6949:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   6950:            else
                   6951:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   6952:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   6953:          }else{ /* more than 2 covariates */
                   6954:            if(cptcoveff ==1){
                   6955:              ioffset=4; /* Age is in 4 */
                   6956:            }else{
                   6957:              ioffset=6; /* Age is in 6 */
                   6958:              /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6959:              /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   6960:            }   
                   6961:            fprintf(ficgp," u %d:(",ioffset); 
                   6962:            kl=0;
                   6963:            strcpy(gplotcondition,"(");
                   6964:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   6965:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   6966:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6967:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6968:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6969:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   6970:              kl++;
                   6971:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   6972:              kl++;
                   6973:              if(k <cptcoveff && cptcoveff>1)
                   6974:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   6975:            }
                   6976:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   6977:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6978:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6979:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6980:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6981:            if(i==nlstate+1){
                   6982:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p.%d' with line ", gplotcondition, \
                   6983:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   6984:            }else{
                   6985:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   6986:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   6987:            }
                   6988:          } /* end if covariate */
                   6989:        } /* nlstate */
                   6990:        fprintf(ficgp,"\nset out\n");
1.223     brouard  6991:       } /* end cpt state*/
                   6992:     } /* end covariate */
                   6993:   } /* End if prevfcast */
1.227     brouard  6994:   
                   6995:   
1.238     brouard  6996:   /* 9eme writing MLE parameters */
                   6997:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  6998:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  6999:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7000:     for(k=1; k <=(nlstate+ndeath); k++){
                   7001:       if (k != i) {
1.227     brouard  7002:        fprintf(ficgp,"#   current state %d\n",k);
                   7003:        for(j=1; j <=ncovmodel; j++){
                   7004:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7005:          jk++; 
                   7006:        }
                   7007:        fprintf(ficgp,"\n");
1.126     brouard  7008:       }
                   7009:     }
1.223     brouard  7010:   }
1.187     brouard  7011:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7012:   
1.145     brouard  7013:   /*goto avoid;*/
1.238     brouard  7014:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7015:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7016:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7017:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7018:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7019:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7020:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7021:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7022:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7023:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7024:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7025:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7026:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7027:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7028:   fprintf(ficgp,"#\n");
1.223     brouard  7029:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7030:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7031:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7032:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.237     brouard  7033:     fprintf(ficgp,"#   jk=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7034:     for(jk=1; jk <=m; jk++)  /* For each combination of covariate */
                   7035:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7036:       if(TKresult[nres]!= jk)
                   7037:        continue;
                   7038:       fprintf(ficgp,"# Combination of dummy  jk=%d and ",jk);
                   7039:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7040:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7041:       }        
                   7042:       fprintf(ficgp,"\n#\n");
1.241     brouard  7043:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng,nres);
1.223     brouard  7044:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7045:       if (ng==1){
                   7046:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7047:        fprintf(ficgp,"\nunset log y");
                   7048:       }else if (ng==2){
                   7049:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7050:        fprintf(ficgp,"\nset log y");
                   7051:       }else if (ng==3){
                   7052:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7053:        fprintf(ficgp,"\nset log y");
                   7054:       }else
                   7055:        fprintf(ficgp,"\nunset title ");
                   7056:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7057:       i=1;
                   7058:       for(k2=1; k2<=nlstate; k2++) {
                   7059:        k3=i;
                   7060:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7061:          if (k != k2){
                   7062:            switch( ng) {
                   7063:            case 1:
                   7064:              if(nagesqr==0)
                   7065:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7066:              else /* nagesqr =1 */
                   7067:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7068:              break;
                   7069:            case 2: /* ng=2 */
                   7070:              if(nagesqr==0)
                   7071:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7072:              else /* nagesqr =1 */
                   7073:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7074:              break;
                   7075:            case 3:
                   7076:              if(nagesqr==0)
                   7077:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7078:              else /* nagesqr =1 */
                   7079:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7080:              break;
                   7081:            }
                   7082:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7083:            ijp=1; /* product no age */
                   7084:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7085:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7086:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.237     brouard  7087:              if(j==Tage[ij]) { /* Product by age */
                   7088:                if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
1.238     brouard  7089:                  if(DummyV[j]==0){
1.237     brouard  7090:                    fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7091:                  }else{ /* quantitative */
                   7092:                    fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7093:                    /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7094:                  }
                   7095:                  ij++;
                   7096:                }
                   7097:              }else if(j==Tprod[ijp]) { /* */ 
                   7098:                /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7099:                if(ijp <=cptcovprod) { /* Product */
1.238     brouard  7100:                  if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7101:                    if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
1.237     brouard  7102:                      /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],nbcode[Tvard[ijp][2]][codtabm(jk,j)]); */
                   7103:                      fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7104:                    }else{ /* Vn is dummy and Vm is quanti */
                   7105:                      /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7106:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7107:                    }
                   7108:                  }else{ /* Vn*Vm Vn is quanti */
1.238     brouard  7109:                    if(DummyV[Tvard[ijp][2]]==0){
1.237     brouard  7110:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7111:                    }else{ /* Both quanti */
                   7112:                      fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7113:                    }
                   7114:                  }
1.238     brouard  7115:                  ijp++;
1.237     brouard  7116:                }
                   7117:              } else{  /* simple covariate */
                   7118:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(jk,j)]); /\* Valgrind bug nbcode *\/ */
                   7119:                if(Dummy[j]==0){
                   7120:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7121:                }else{ /* quantitative */
                   7122:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.223     brouard  7123:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7124:                }
1.237     brouard  7125:              } /* end simple */
                   7126:            } /* end j */
1.223     brouard  7127:          }else{
                   7128:            i=i-ncovmodel;
                   7129:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7130:              fprintf(ficgp," (1.");
                   7131:          }
1.227     brouard  7132:          
1.223     brouard  7133:          if(ng != 1){
                   7134:            fprintf(ficgp,")/(1");
1.227     brouard  7135:            
1.223     brouard  7136:            for(k1=1; k1 <=nlstate; k1++){ 
                   7137:              if(nagesqr==0)
                   7138:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                   7139:              else /* nagesqr =1 */
                   7140:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1,k3+(k1-1)*ncovmodel+1+nagesqr);
1.217     brouard  7141:               
1.223     brouard  7142:              ij=1;
                   7143:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.237     brouard  7144:                if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7145:                  if(ij <=cptcovage) { /* Bug valgrind */
1.223     brouard  7146:                    fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                   7147:                    /* fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7148:                    ij++;
                   7149:                  }
                   7150:                }
                   7151:                else
1.225     brouard  7152:                  fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7153:              }
                   7154:              fprintf(ficgp,")");
                   7155:            }
                   7156:            fprintf(ficgp,")");
                   7157:            if(ng ==2)
                   7158:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   7159:            else /* ng= 3 */
                   7160:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   7161:          }else{ /* end ng <> 1 */
                   7162:            if( k !=k2) /* logit p11 is hard to draw */
                   7163:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   7164:          }
                   7165:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7166:            fprintf(ficgp,",");
                   7167:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7168:            fprintf(ficgp,",");
                   7169:          i=i+ncovmodel;
                   7170:        } /* end k */
                   7171:       } /* end k2 */
                   7172:       fprintf(ficgp,"\n set out\n");
                   7173:     } /* end jk */
                   7174:   } /* end ng */
                   7175:   /* avoid: */
                   7176:   fflush(ficgp); 
1.126     brouard  7177: }  /* end gnuplot */
                   7178: 
                   7179: 
                   7180: /*************** Moving average **************/
1.219     brouard  7181: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  7182:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  7183:    
1.222     brouard  7184:    int i, cpt, cptcod;
                   7185:    int modcovmax =1;
                   7186:    int mobilavrange, mob;
                   7187:    int iage=0;
                   7188: 
                   7189:    double sum=0.;
                   7190:    double age;
                   7191:    double *sumnewp, *sumnewm;
                   7192:    double *agemingood, *agemaxgood; /* Currently identical for all covariates */
                   7193:   
                   7194:   
1.225     brouard  7195:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  7196:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   7197: 
                   7198:    sumnewp = vector(1,ncovcombmax);
                   7199:    sumnewm = vector(1,ncovcombmax);
                   7200:    agemingood = vector(1,ncovcombmax); 
                   7201:    agemaxgood = vector(1,ncovcombmax);
                   7202: 
                   7203:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7204:      sumnewm[cptcod]=0.;
                   7205:      sumnewp[cptcod]=0.;
                   7206:      agemingood[cptcod]=0;
                   7207:      agemaxgood[cptcod]=0;
                   7208:    }
                   7209:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   7210:   
                   7211:    if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   7212:      if(mobilav==1) mobilavrange=5; /* default */
                   7213:      else mobilavrange=mobilav;
                   7214:      for (age=bage; age<=fage; age++)
                   7215:        for (i=1; i<=nlstate;i++)
                   7216:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   7217:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   7218:      /* We keep the original values on the extreme ages bage, fage and for 
                   7219:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   7220:        we use a 5 terms etc. until the borders are no more concerned. 
                   7221:      */ 
                   7222:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   7223:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
                   7224:         for (i=1; i<=nlstate;i++){
                   7225:           for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7226:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   7227:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   7228:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   7229:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   7230:             }
                   7231:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
                   7232:           }
                   7233:         }
                   7234:        }/* end age */
                   7235:      }/* end mob */
                   7236:    }else
                   7237:      return -1;
                   7238:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7239:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7240:      if(invalidvarcomb[cptcod]){
                   7241:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7242:        continue;
                   7243:      }
1.219     brouard  7244: 
1.222     brouard  7245:      agemingood[cptcod]=fage-(mob-1)/2;
                   7246:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, finding the youngest wrong */
                   7247:        sumnewm[cptcod]=0.;
                   7248:        for (i=1; i<=nlstate;i++){
                   7249:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7250:        }
                   7251:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7252:         agemingood[cptcod]=age;
                   7253:        }else{ /* bad */
                   7254:         for (i=1; i<=nlstate;i++){
                   7255:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7256:         } /* i */
                   7257:        } /* end bad */
                   7258:      }/* age */
                   7259:      sum=0.;
                   7260:      for (i=1; i<=nlstate;i++){
                   7261:        sum+=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7262:      }
                   7263:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7264:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any descending age!\n",cptcod);
                   7265:        /* for (i=1; i<=nlstate;i++){ */
                   7266:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7267:        /* } /\* i *\/ */
                   7268:      } /* end bad */
                   7269:      /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   7270:      /* From youngest, finding the oldest wrong */
                   7271:      agemaxgood[cptcod]=bage+(mob-1)/2;
                   7272:      for (age=bage+(mob-1)/2; age<=fage; age++){
                   7273:        sumnewm[cptcod]=0.;
                   7274:        for (i=1; i<=nlstate;i++){
                   7275:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7276:        }
                   7277:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7278:         agemaxgood[cptcod]=age;
                   7279:        }else{ /* bad */
                   7280:         for (i=1; i<=nlstate;i++){
                   7281:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7282:         } /* i */
                   7283:        } /* end bad */
                   7284:      }/* age */
                   7285:      sum=0.;
                   7286:      for (i=1; i<=nlstate;i++){
                   7287:        sum+=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7288:      }
                   7289:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7290:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any ascending age!\n",cptcod);
                   7291:        /* for (i=1; i<=nlstate;i++){ */
                   7292:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7293:        /* } /\* i *\/ */
                   7294:      } /* end bad */
                   7295:                
                   7296:      for (age=bage; age<=fage; age++){
1.235     brouard  7297:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  7298:        sumnewp[cptcod]=0.;
                   7299:        sumnewm[cptcod]=0.;
                   7300:        for (i=1; i<=nlstate;i++){
                   7301:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   7302:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7303:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   7304:        }
                   7305:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   7306:      }
                   7307:      /* printf("\n"); */
                   7308:      /* } */
                   7309:      /* brutal averaging */
                   7310:      for (i=1; i<=nlstate;i++){
                   7311:        for (age=1; age<=bage; age++){
                   7312:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7313:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7314:        }       
                   7315:        for (age=fage; age<=AGESUP; age++){
                   7316:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7317:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7318:        }
                   7319:      } /* end i status */
                   7320:      for (i=nlstate+1; i<=nlstate+ndeath;i++){
                   7321:        for (age=1; age<=AGESUP; age++){
                   7322:         /*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*/
                   7323:         mobaverage[(int)age][i][cptcod]=0.;
                   7324:        }
                   7325:      }
                   7326:    }/* end cptcod */
                   7327:    free_vector(sumnewm,1, ncovcombmax);
                   7328:    free_vector(sumnewp,1, ncovcombmax);
                   7329:    free_vector(agemaxgood,1, ncovcombmax);
                   7330:    free_vector(agemingood,1, ncovcombmax);
                   7331:    return 0;
                   7332:  }/* End movingaverage */
1.218     brouard  7333:  
1.126     brouard  7334: 
                   7335: /************** Forecasting ******************/
1.235     brouard  7336:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  7337:   /* proj1, year, month, day of starting projection 
                   7338:      agemin, agemax range of age
                   7339:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   7340:      anproj2 year of en of projection (same day and month as proj1).
                   7341:   */
1.235     brouard  7342:    int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  7343:   double agec; /* generic age */
                   7344:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   7345:   double *popeffectif,*popcount;
                   7346:   double ***p3mat;
1.218     brouard  7347:   /* double ***mobaverage; */
1.126     brouard  7348:   char fileresf[FILENAMELENGTH];
                   7349: 
                   7350:   agelim=AGESUP;
1.211     brouard  7351:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   7352:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   7353:      We still use firstpass and lastpass as another selection.
                   7354:   */
1.214     brouard  7355:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   7356:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  7357:  
1.201     brouard  7358:   strcpy(fileresf,"F_"); 
                   7359:   strcat(fileresf,fileresu);
1.126     brouard  7360:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   7361:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   7362:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   7363:   }
1.235     brouard  7364:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   7365:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  7366: 
1.225     brouard  7367:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  7368: 
                   7369: 
                   7370:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   7371:   if (stepm<=12) stepsize=1;
                   7372:   if(estepm < stepm){
                   7373:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   7374:   }
                   7375:   else  hstepm=estepm;   
                   7376: 
                   7377:   hstepm=hstepm/stepm; 
                   7378:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   7379:                                fractional in yp1 */
                   7380:   anprojmean=yp;
                   7381:   yp2=modf((yp1*12),&yp);
                   7382:   mprojmean=yp;
                   7383:   yp1=modf((yp2*30.5),&yp);
                   7384:   jprojmean=yp;
                   7385:   if(jprojmean==0) jprojmean=1;
                   7386:   if(mprojmean==0) jprojmean=1;
                   7387: 
1.227     brouard  7388:   i1=pow(2,cptcoveff);
1.126     brouard  7389:   if (cptcovn < 1){i1=1;}
                   7390:   
                   7391:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   7392:   
                   7393:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  7394:   
1.126     brouard  7395: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  7396:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7397:   for(k=1; k<=i1;k++){
                   7398:     if(TKresult[nres]!= k)
                   7399:       continue;
1.227     brouard  7400:     if(invalidvarcomb[k]){
                   7401:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   7402:       continue;
                   7403:     }
                   7404:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   7405:     for(j=1;j<=cptcoveff;j++) {
                   7406:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7407:     }
1.235     brouard  7408:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7409:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  7410:     }
1.227     brouard  7411:     fprintf(ficresf," yearproj age");
                   7412:     for(j=1; j<=nlstate+ndeath;j++){ 
                   7413:       for(i=1; i<=nlstate;i++)               
                   7414:        fprintf(ficresf," p%d%d",i,j);
                   7415:       fprintf(ficresf," wp.%d",j);
                   7416:     }
                   7417:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   7418:       fprintf(ficresf,"\n");
                   7419:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
                   7420:       for (agec=fage; agec>=(ageminpar-1); agec--){ 
                   7421:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   7422:        nhstepm = nhstepm/hstepm; 
                   7423:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7424:        oldm=oldms;savm=savms;
1.235     brouard  7425:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.227     brouard  7426:        
                   7427:        for (h=0; h<=nhstepm; h++){
                   7428:          if (h*hstepm/YEARM*stepm ==yearp) {
                   7429:            fprintf(ficresf,"\n");
                   7430:            for(j=1;j<=cptcoveff;j++) 
                   7431:              fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7432:            fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   7433:          } 
                   7434:          for(j=1; j<=nlstate+ndeath;j++) {
                   7435:            ppij=0.;
                   7436:            for(i=1; i<=nlstate;i++) {
                   7437:              if (mobilav==1) 
                   7438:                ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][k];
                   7439:              else {
                   7440:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   7441:              }
                   7442:              if (h*hstepm/YEARM*stepm== yearp) {
                   7443:                fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   7444:              }
                   7445:            } /* end i */
                   7446:            if (h*hstepm/YEARM*stepm==yearp) {
                   7447:              fprintf(ficresf," %.3f", ppij);
                   7448:            }
                   7449:          }/* end j */
                   7450:        } /* end h */
                   7451:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7452:       } /* end agec */
                   7453:     } /* end yearp */
                   7454:   } /* end  k */
1.219     brouard  7455:        
1.126     brouard  7456:   fclose(ficresf);
1.215     brouard  7457:   printf("End of Computing forecasting \n");
                   7458:   fprintf(ficlog,"End of Computing forecasting\n");
                   7459: 
1.126     brouard  7460: }
                   7461: 
1.218     brouard  7462: /* /\************** Back Forecasting ******************\/ */
1.225     brouard  7463: /* void prevbackforecast(char fileres[], double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
1.218     brouard  7464: /*   /\* back1, year, month, day of starting backection  */
                   7465: /*      agemin, agemax range of age */
                   7466: /*      dateprev1 dateprev2 range of dates during which prevalence is computed */
                   7467: /*      anback2 year of en of backection (same day and month as back1). */
                   7468: /*   *\/ */
                   7469: /*   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1; */
                   7470: /*   double agec; /\* generic age *\/ */
                   7471: /*   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean; */
                   7472: /*   double *popeffectif,*popcount; */
                   7473: /*   double ***p3mat; */
                   7474: /*   /\* double ***mobaverage; *\/ */
                   7475: /*   char fileresfb[FILENAMELENGTH]; */
                   7476:        
                   7477: /*   agelim=AGESUP; */
                   7478: /*   /\* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people */
                   7479: /*      in each health status at the date of interview (if between dateprev1 and dateprev2). */
                   7480: /*      We still use firstpass and lastpass as another selection. */
                   7481: /*   *\/ */
                   7482: /*   /\* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ *\/ */
                   7483: /*   /\*             firstpass, lastpass,  stepm,  weightopt, model); *\/ */
                   7484: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   7485:        
                   7486: /*   strcpy(fileresfb,"FB_");  */
                   7487: /*   strcat(fileresfb,fileresu); */
                   7488: /*   if((ficresfb=fopen(fileresfb,"w"))==NULL) { */
                   7489: /*     printf("Problem with back forecast resultfile: %s\n", fileresfb); */
                   7490: /*     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb); */
                   7491: /*   } */
                   7492: /*   printf("Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7493: /*   fprintf(ficlog,"Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7494:        
1.225     brouard  7495: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.218     brouard  7496:        
                   7497: /*   /\* if (mobilav!=0) { *\/ */
                   7498: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7499: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7500: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7501: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7502: /*   /\*   } *\/ */
                   7503: /*   /\* } *\/ */
                   7504:        
                   7505: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7506: /*   if (stepm<=12) stepsize=1; */
                   7507: /*   if(estepm < stepm){ */
                   7508: /*     printf ("Problem %d lower than %d\n",estepm, stepm); */
                   7509: /*   } */
                   7510: /*   else  hstepm=estepm;    */
                   7511:        
                   7512: /*   hstepm=hstepm/stepm;  */
                   7513: /*   yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   7514: /*                                fractional in yp1 *\/ */
                   7515: /*   anprojmean=yp; */
                   7516: /*   yp2=modf((yp1*12),&yp); */
                   7517: /*   mprojmean=yp; */
                   7518: /*   yp1=modf((yp2*30.5),&yp); */
                   7519: /*   jprojmean=yp; */
                   7520: /*   if(jprojmean==0) jprojmean=1; */
                   7521: /*   if(mprojmean==0) jprojmean=1; */
                   7522:        
1.225     brouard  7523: /*   i1=cptcoveff; */
1.218     brouard  7524: /*   if (cptcovn < 1){i1=1;} */
1.217     brouard  7525:   
1.218     brouard  7526: /*   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);  */
1.217     brouard  7527:   
1.218     brouard  7528: /*   fprintf(ficresfb,"#****** Routine prevbackforecast **\n"); */
                   7529:        
                   7530: /*     /\*           if (h==(int)(YEARM*yearp)){ *\/ */
                   7531: /*   for(cptcov=1, k=0;cptcov<=i1;cptcov++){ */
1.225     brouard  7532: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
1.218     brouard  7533: /*       k=k+1; */
                   7534: /*       fprintf(ficresfb,"\n#****** hbijx=probability over h years, hp.jx is weighted by observed prev \n#"); */
1.225     brouard  7535: /*       for(j=1;j<=cptcoveff;j++) { */
1.218     brouard  7536: /*                             fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7537: /*       } */
                   7538: /*       fprintf(ficresfb," yearbproj age"); */
                   7539: /*       for(j=1; j<=nlstate+ndeath;j++){  */
                   7540: /*                             for(i=1; i<=nlstate;i++)               */
                   7541: /*           fprintf(ficresfb," p%d%d",i,j); */
                   7542: /*                             fprintf(ficresfb," p.%d",j); */
                   7543: /*       } */
                   7544: /*       for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {  */
                   7545: /*                             /\* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  *\/ */
                   7546: /*                             fprintf(ficresfb,"\n"); */
                   7547: /*                             fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);    */
                   7548: /*                             for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   7549: /*                                     nhstepm=(int) rint((agelim-agec)*YEARM/stepm);  */
                   7550: /*                                     nhstepm = nhstepm/hstepm;  */
                   7551: /*                                     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7552: /*                                     oldm=oldms;savm=savms; */
                   7553: /*                                     hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm,oldm,savm, dnewm, doldm, dsavm, k);       */
                   7554: /*                                     for (h=0; h<=nhstepm; h++){ */
                   7555: /*                                             if (h*hstepm/YEARM*stepm ==yearp) { */
                   7556: /*               fprintf(ficresfb,"\n"); */
1.225     brouard  7557: /*               for(j=1;j<=cptcoveff;j++)  */
1.218     brouard  7558: /*                 fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7559: /*                                                     fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec+h*hstepm/YEARM*stepm); */
                   7560: /*                                             }  */
                   7561: /*                                             for(j=1; j<=nlstate+ndeath;j++) { */
                   7562: /*                                                     ppij=0.; */
                   7563: /*                                                     for(i=1; i<=nlstate;i++) { */
                   7564: /*                                                             if (mobilav==1)  */
                   7565: /*                                                                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod]; */
                   7566: /*                                                             else { */
                   7567: /*                                                                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod]; */
                   7568: /*                                                             } */
                   7569: /*                                                             if (h*hstepm/YEARM*stepm== yearp) { */
                   7570: /*                                                                     fprintf(ficresfb," %.3f", p3mat[i][j][h]); */
                   7571: /*                                                             } */
                   7572: /*                                                     } /\* end i *\/ */
                   7573: /*                                                     if (h*hstepm/YEARM*stepm==yearp) { */
                   7574: /*                                                             fprintf(ficresfb," %.3f", ppij); */
                   7575: /*                                                     } */
                   7576: /*                                             }/\* end j *\/ */
                   7577: /*                                     } /\* end h *\/ */
                   7578: /*                                     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7579: /*                             } /\* end agec *\/ */
                   7580: /*       } /\* end yearp *\/ */
                   7581: /*     } /\* end cptcod *\/ */
                   7582: /*   } /\* end  cptcov *\/ */
                   7583:        
                   7584: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7585:        
                   7586: /*   fclose(ficresfb); */
                   7587: /*   printf("End of Computing Back forecasting \n"); */
                   7588: /*   fprintf(ficlog,"End of Computing Back forecasting\n"); */
1.217     brouard  7589:        
1.218     brouard  7590: /* } */
1.217     brouard  7591: 
1.126     brouard  7592: /************** Forecasting *****not tested NB*************/
1.227     brouard  7593: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  7594:   
1.227     brouard  7595: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   7596: /*   int *popage; */
                   7597: /*   double calagedatem, agelim, kk1, kk2; */
                   7598: /*   double *popeffectif,*popcount; */
                   7599: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   7600: /*   /\* double ***mobaverage; *\/ */
                   7601: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  7602: 
1.227     brouard  7603: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7604: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7605: /*   agelim=AGESUP; */
                   7606: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  7607:   
1.227     brouard  7608: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  7609:   
                   7610:   
1.227     brouard  7611: /*   strcpy(filerespop,"POP_");  */
                   7612: /*   strcat(filerespop,fileresu); */
                   7613: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   7614: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   7615: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   7616: /*   } */
                   7617: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   7618: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  7619: 
1.227     brouard  7620: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  7621: 
1.227     brouard  7622: /*   /\* if (mobilav!=0) { *\/ */
                   7623: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7624: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7625: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7626: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7627: /*   /\*   } *\/ */
                   7628: /*   /\* } *\/ */
1.126     brouard  7629: 
1.227     brouard  7630: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7631: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  7632:   
1.227     brouard  7633: /*   agelim=AGESUP; */
1.126     brouard  7634:   
1.227     brouard  7635: /*   hstepm=1; */
                   7636: /*   hstepm=hstepm/stepm;  */
1.218     brouard  7637:        
1.227     brouard  7638: /*   if (popforecast==1) { */
                   7639: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   7640: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   7641: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   7642: /*     }  */
                   7643: /*     popage=ivector(0,AGESUP); */
                   7644: /*     popeffectif=vector(0,AGESUP); */
                   7645: /*     popcount=vector(0,AGESUP); */
1.126     brouard  7646:     
1.227     brouard  7647: /*     i=1;    */
                   7648: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  7649:     
1.227     brouard  7650: /*     imx=i; */
                   7651: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   7652: /*   } */
1.218     brouard  7653:   
1.227     brouard  7654: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   7655: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   7656: /*       k=k+1; */
                   7657: /*       fprintf(ficrespop,"\n#******"); */
                   7658: /*       for(j=1;j<=cptcoveff;j++) { */
                   7659: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7660: /*       } */
                   7661: /*       fprintf(ficrespop,"******\n"); */
                   7662: /*       fprintf(ficrespop,"# Age"); */
                   7663: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   7664: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  7665:       
1.227     brouard  7666: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   7667: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  7668:        
1.227     brouard  7669: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7670: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7671: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7672:          
1.227     brouard  7673: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7674: /*       oldm=oldms;savm=savms; */
                   7675: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  7676:          
1.227     brouard  7677: /*       for (h=0; h<=nhstepm; h++){ */
                   7678: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7679: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7680: /*         }  */
                   7681: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7682: /*           kk1=0.;kk2=0; */
                   7683: /*           for(i=1; i<=nlstate;i++) {               */
                   7684: /*             if (mobilav==1)  */
                   7685: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   7686: /*             else { */
                   7687: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   7688: /*             } */
                   7689: /*           } */
                   7690: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   7691: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   7692: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   7693: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   7694: /*           } */
                   7695: /*         } */
                   7696: /*         for(i=1; i<=nlstate;i++){ */
                   7697: /*           kk1=0.; */
                   7698: /*           for(j=1; j<=nlstate;j++){ */
                   7699: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   7700: /*           } */
                   7701: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   7702: /*         } */
1.218     brouard  7703:            
1.227     brouard  7704: /*         if (h==(int)(calagedatem+12*cpt)) */
                   7705: /*           for(j=1; j<=nlstate;j++)  */
                   7706: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   7707: /*       } */
                   7708: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7709: /*     } */
                   7710: /*       } */
1.218     brouard  7711:       
1.227     brouard  7712: /*       /\******\/ */
1.218     brouard  7713:       
1.227     brouard  7714: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   7715: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   7716: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7717: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7718: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7719:          
1.227     brouard  7720: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7721: /*       oldm=oldms;savm=savms; */
                   7722: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   7723: /*       for (h=0; h<=nhstepm; h++){ */
                   7724: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7725: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7726: /*         }  */
                   7727: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7728: /*           kk1=0.;kk2=0; */
                   7729: /*           for(i=1; i<=nlstate;i++) {               */
                   7730: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   7731: /*           } */
                   7732: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   7733: /*         } */
                   7734: /*       } */
                   7735: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7736: /*     } */
                   7737: /*       } */
                   7738: /*     }  */
                   7739: /*   } */
1.218     brouard  7740:   
1.227     brouard  7741: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  7742:   
1.227     brouard  7743: /*   if (popforecast==1) { */
                   7744: /*     free_ivector(popage,0,AGESUP); */
                   7745: /*     free_vector(popeffectif,0,AGESUP); */
                   7746: /*     free_vector(popcount,0,AGESUP); */
                   7747: /*   } */
                   7748: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7749: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7750: /*   fclose(ficrespop); */
                   7751: /* } /\* End of popforecast *\/ */
1.218     brouard  7752:  
1.126     brouard  7753: int fileappend(FILE *fichier, char *optionfich)
                   7754: {
                   7755:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   7756:     printf("Problem with file: %s\n", optionfich);
                   7757:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   7758:     return (0);
                   7759:   }
                   7760:   fflush(fichier);
                   7761:   return (1);
                   7762: }
                   7763: 
                   7764: 
                   7765: /**************** function prwizard **********************/
                   7766: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   7767: {
                   7768: 
                   7769:   /* Wizard to print covariance matrix template */
                   7770: 
1.164     brouard  7771:   char ca[32], cb[32];
                   7772:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  7773:   int numlinepar;
                   7774: 
                   7775:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7776:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7777:   for(i=1; i <=nlstate; i++){
                   7778:     jj=0;
                   7779:     for(j=1; j <=nlstate+ndeath; j++){
                   7780:       if(j==i) continue;
                   7781:       jj++;
                   7782:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   7783:       printf("%1d%1d",i,j);
                   7784:       fprintf(ficparo,"%1d%1d",i,j);
                   7785:       for(k=1; k<=ncovmodel;k++){
                   7786:        /*        printf(" %lf",param[i][j][k]); */
                   7787:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   7788:        printf(" 0.");
                   7789:        fprintf(ficparo," 0.");
                   7790:       }
                   7791:       printf("\n");
                   7792:       fprintf(ficparo,"\n");
                   7793:     }
                   7794:   }
                   7795:   printf("# Scales (for hessian or gradient estimation)\n");
                   7796:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   7797:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   7798:   for(i=1; i <=nlstate; i++){
                   7799:     jj=0;
                   7800:     for(j=1; j <=nlstate+ndeath; j++){
                   7801:       if(j==i) continue;
                   7802:       jj++;
                   7803:       fprintf(ficparo,"%1d%1d",i,j);
                   7804:       printf("%1d%1d",i,j);
                   7805:       fflush(stdout);
                   7806:       for(k=1; k<=ncovmodel;k++){
                   7807:        /*      printf(" %le",delti3[i][j][k]); */
                   7808:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   7809:        printf(" 0.");
                   7810:        fprintf(ficparo," 0.");
                   7811:       }
                   7812:       numlinepar++;
                   7813:       printf("\n");
                   7814:       fprintf(ficparo,"\n");
                   7815:     }
                   7816:   }
                   7817:   printf("# Covariance matrix\n");
                   7818: /* # 121 Var(a12)\n\ */
                   7819: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7820: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   7821: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   7822: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   7823: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   7824: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   7825: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   7826:   fflush(stdout);
                   7827:   fprintf(ficparo,"# Covariance matrix\n");
                   7828:   /* # 121 Var(a12)\n\ */
                   7829:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7830:   /* #   ...\n\ */
                   7831:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   7832:   
                   7833:   for(itimes=1;itimes<=2;itimes++){
                   7834:     jj=0;
                   7835:     for(i=1; i <=nlstate; i++){
                   7836:       for(j=1; j <=nlstate+ndeath; j++){
                   7837:        if(j==i) continue;
                   7838:        for(k=1; k<=ncovmodel;k++){
                   7839:          jj++;
                   7840:          ca[0]= k+'a'-1;ca[1]='\0';
                   7841:          if(itimes==1){
                   7842:            printf("#%1d%1d%d",i,j,k);
                   7843:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   7844:          }else{
                   7845:            printf("%1d%1d%d",i,j,k);
                   7846:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   7847:            /*  printf(" %.5le",matcov[i][j]); */
                   7848:          }
                   7849:          ll=0;
                   7850:          for(li=1;li <=nlstate; li++){
                   7851:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   7852:              if(lj==li) continue;
                   7853:              for(lk=1;lk<=ncovmodel;lk++){
                   7854:                ll++;
                   7855:                if(ll<=jj){
                   7856:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   7857:                  if(ll<jj){
                   7858:                    if(itimes==1){
                   7859:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7860:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7861:                    }else{
                   7862:                      printf(" 0.");
                   7863:                      fprintf(ficparo," 0.");
                   7864:                    }
                   7865:                  }else{
                   7866:                    if(itimes==1){
                   7867:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   7868:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   7869:                    }else{
                   7870:                      printf(" 0.");
                   7871:                      fprintf(ficparo," 0.");
                   7872:                    }
                   7873:                  }
                   7874:                }
                   7875:              } /* end lk */
                   7876:            } /* end lj */
                   7877:          } /* end li */
                   7878:          printf("\n");
                   7879:          fprintf(ficparo,"\n");
                   7880:          numlinepar++;
                   7881:        } /* end k*/
                   7882:       } /*end j */
                   7883:     } /* end i */
                   7884:   } /* end itimes */
                   7885: 
                   7886: } /* end of prwizard */
                   7887: /******************* Gompertz Likelihood ******************************/
                   7888: double gompertz(double x[])
                   7889: { 
                   7890:   double A,B,L=0.0,sump=0.,num=0.;
                   7891:   int i,n=0; /* n is the size of the sample */
                   7892: 
1.220     brouard  7893:   for (i=1;i<=imx ; i++) {
1.126     brouard  7894:     sump=sump+weight[i];
                   7895:     /*    sump=sump+1;*/
                   7896:     num=num+1;
                   7897:   }
                   7898:  
                   7899:  
                   7900:   /* for (i=0; i<=imx; i++) 
                   7901:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   7902: 
                   7903:   for (i=1;i<=imx ; i++)
                   7904:     {
                   7905:       if (cens[i] == 1 && wav[i]>1)
                   7906:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   7907:       
                   7908:       if (cens[i] == 0 && wav[i]>1)
                   7909:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   7910:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   7911:       
                   7912:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   7913:       if (wav[i] > 1 ) { /* ??? */
                   7914:        L=L+A*weight[i];
                   7915:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   7916:       }
                   7917:     }
                   7918: 
                   7919:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   7920:  
                   7921:   return -2*L*num/sump;
                   7922: }
                   7923: 
1.136     brouard  7924: #ifdef GSL
                   7925: /******************* Gompertz_f Likelihood ******************************/
                   7926: double gompertz_f(const gsl_vector *v, void *params)
                   7927: { 
                   7928:   double A,B,LL=0.0,sump=0.,num=0.;
                   7929:   double *x= (double *) v->data;
                   7930:   int i,n=0; /* n is the size of the sample */
                   7931: 
                   7932:   for (i=0;i<=imx-1 ; i++) {
                   7933:     sump=sump+weight[i];
                   7934:     /*    sump=sump+1;*/
                   7935:     num=num+1;
                   7936:   }
                   7937:  
                   7938:  
                   7939:   /* for (i=0; i<=imx; i++) 
                   7940:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   7941:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   7942:   for (i=1;i<=imx ; i++)
                   7943:     {
                   7944:       if (cens[i] == 1 && wav[i]>1)
                   7945:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   7946:       
                   7947:       if (cens[i] == 0 && wav[i]>1)
                   7948:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   7949:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   7950:       
                   7951:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   7952:       if (wav[i] > 1 ) { /* ??? */
                   7953:        LL=LL+A*weight[i];
                   7954:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   7955:       }
                   7956:     }
                   7957: 
                   7958:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   7959:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   7960:  
                   7961:   return -2*LL*num/sump;
                   7962: }
                   7963: #endif
                   7964: 
1.126     brouard  7965: /******************* Printing html file ***********/
1.201     brouard  7966: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  7967:                  int lastpass, int stepm, int weightopt, char model[],\
                   7968:                  int imx,  double p[],double **matcov,double agemortsup){
                   7969:   int i,k;
                   7970: 
                   7971:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   7972:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   7973:   for (i=1;i<=2;i++) 
                   7974:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  7975:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  7976:   fprintf(fichtm,"</ul>");
                   7977: 
                   7978: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   7979: 
                   7980:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   7981: 
                   7982:  for (k=agegomp;k<(agemortsup-2);k++) 
                   7983:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   7984: 
                   7985:  
                   7986:   fflush(fichtm);
                   7987: }
                   7988: 
                   7989: /******************* Gnuplot file **************/
1.201     brouard  7990: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  7991: 
                   7992:   char dirfileres[132],optfileres[132];
1.164     brouard  7993: 
1.126     brouard  7994:   int ng;
                   7995: 
                   7996: 
                   7997:   /*#ifdef windows */
                   7998:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   7999:     /*#endif */
                   8000: 
                   8001: 
                   8002:   strcpy(dirfileres,optionfilefiname);
                   8003:   strcpy(optfileres,"vpl");
1.199     brouard  8004:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  8005:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  8006:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  8007:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  8008:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   8009: 
                   8010: } 
                   8011: 
1.136     brouard  8012: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   8013: {
1.126     brouard  8014: 
1.136     brouard  8015:   /*-------- data file ----------*/
                   8016:   FILE *fic;
                   8017:   char dummy[]="                         ";
1.240     brouard  8018:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  8019:   int lstra;
1.136     brouard  8020:   int linei, month, year,iout;
                   8021:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  8022:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  8023:   char *stratrunc;
1.223     brouard  8024: 
1.240     brouard  8025:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   8026:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  8027: 
1.240     brouard  8028:   for(v=1; v <=ncovcol;v++){
                   8029:     DummyV[v]=0;
                   8030:     FixedV[v]=0;
                   8031:   }
                   8032:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   8033:     DummyV[v]=1;
                   8034:     FixedV[v]=0;
                   8035:   }
                   8036:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   8037:     DummyV[v]=0;
                   8038:     FixedV[v]=1;
                   8039:   }
                   8040:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8041:     DummyV[v]=1;
                   8042:     FixedV[v]=1;
                   8043:   }
                   8044:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8045:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8046:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8047:   }
1.126     brouard  8048: 
1.136     brouard  8049:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  8050:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   8051:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  8052:   }
1.126     brouard  8053: 
1.136     brouard  8054:   i=1;
                   8055:   linei=0;
                   8056:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   8057:     linei=linei+1;
                   8058:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   8059:       if(line[j] == '\t')
                   8060:        line[j] = ' ';
                   8061:     }
                   8062:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   8063:       ;
                   8064:     };
                   8065:     line[j+1]=0;  /* Trims blanks at end of line */
                   8066:     if(line[0]=='#'){
                   8067:       fprintf(ficlog,"Comment line\n%s\n",line);
                   8068:       printf("Comment line\n%s\n",line);
                   8069:       continue;
                   8070:     }
                   8071:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  8072:     strcpy(line, linetmp);
1.223     brouard  8073:     
                   8074:     /* Loops on waves */
                   8075:     for (j=maxwav;j>=1;j--){
                   8076:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  8077:        cutv(stra, strb, line, ' '); 
                   8078:        if(strb[0]=='.') { /* Missing value */
                   8079:          lval=-1;
                   8080:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   8081:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   8082:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   8083:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   8084:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   8085:            return 1;
                   8086:          }
                   8087:        }else{
                   8088:          errno=0;
                   8089:          /* what_kind_of_number(strb); */
                   8090:          dval=strtod(strb,&endptr); 
                   8091:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   8092:          /* if(strb != endptr && *endptr == '\0') */
                   8093:          /*    dval=dlval; */
                   8094:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8095:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8096:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   8097:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   8098:            return 1;
                   8099:          }
                   8100:          cotqvar[j][iv][i]=dval; 
                   8101:          cotvar[j][ntv+iv][i]=dval; 
                   8102:        }
                   8103:        strcpy(line,stra);
1.223     brouard  8104:       }/* end loop ntqv */
1.225     brouard  8105:       
1.223     brouard  8106:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  8107:        cutv(stra, strb, line, ' '); 
                   8108:        if(strb[0]=='.') { /* Missing value */
                   8109:          lval=-1;
                   8110:        }else{
                   8111:          errno=0;
                   8112:          lval=strtol(strb,&endptr,10); 
                   8113:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8114:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8115:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   8116:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   8117:            return 1;
                   8118:          }
                   8119:        }
                   8120:        if(lval <-1 || lval >1){
                   8121:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8122:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8123:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8124:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8125:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8126:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8127:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8128:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8129:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  8130:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8131:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8132:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8133:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8134:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8135:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8136:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8137:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8138:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  8139:          return 1;
                   8140:        }
                   8141:        cotvar[j][iv][i]=(double)(lval);
                   8142:        strcpy(line,stra);
1.223     brouard  8143:       }/* end loop ntv */
1.225     brouard  8144:       
1.223     brouard  8145:       /* Statuses  at wave */
1.137     brouard  8146:       cutv(stra, strb, line, ' '); 
1.223     brouard  8147:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  8148:        lval=-1;
1.136     brouard  8149:       }else{
1.238     brouard  8150:        errno=0;
                   8151:        lval=strtol(strb,&endptr,10); 
                   8152:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8153:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8154:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   8155:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   8156:          return 1;
                   8157:        }
1.136     brouard  8158:       }
1.225     brouard  8159:       
1.136     brouard  8160:       s[j][i]=lval;
1.225     brouard  8161:       
1.223     brouard  8162:       /* Date of Interview */
1.136     brouard  8163:       strcpy(line,stra);
                   8164:       cutv(stra, strb,line,' ');
1.169     brouard  8165:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8166:       }
1.169     brouard  8167:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  8168:        month=99;
                   8169:        year=9999;
1.136     brouard  8170:       }else{
1.225     brouard  8171:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   8172:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   8173:        return 1;
1.136     brouard  8174:       }
                   8175:       anint[j][i]= (double) year; 
                   8176:       mint[j][i]= (double)month; 
                   8177:       strcpy(line,stra);
1.223     brouard  8178:     } /* End loop on waves */
1.225     brouard  8179:     
1.223     brouard  8180:     /* Date of death */
1.136     brouard  8181:     cutv(stra, strb,line,' '); 
1.169     brouard  8182:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8183:     }
1.169     brouard  8184:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  8185:       month=99;
                   8186:       year=9999;
                   8187:     }else{
1.141     brouard  8188:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  8189:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   8190:       return 1;
1.136     brouard  8191:     }
                   8192:     andc[i]=(double) year; 
                   8193:     moisdc[i]=(double) month; 
                   8194:     strcpy(line,stra);
                   8195:     
1.223     brouard  8196:     /* Date of birth */
1.136     brouard  8197:     cutv(stra, strb,line,' '); 
1.169     brouard  8198:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8199:     }
1.169     brouard  8200:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  8201:       month=99;
                   8202:       year=9999;
                   8203:     }else{
1.141     brouard  8204:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   8205:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8206:       return 1;
1.136     brouard  8207:     }
                   8208:     if (year==9999) {
1.141     brouard  8209:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   8210:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8211:       return 1;
                   8212:       
1.136     brouard  8213:     }
                   8214:     annais[i]=(double)(year);
                   8215:     moisnais[i]=(double)(month); 
                   8216:     strcpy(line,stra);
1.225     brouard  8217:     
1.223     brouard  8218:     /* Sample weight */
1.136     brouard  8219:     cutv(stra, strb,line,' '); 
                   8220:     errno=0;
                   8221:     dval=strtod(strb,&endptr); 
                   8222:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  8223:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   8224:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  8225:       fflush(ficlog);
                   8226:       return 1;
                   8227:     }
                   8228:     weight[i]=dval; 
                   8229:     strcpy(line,stra);
1.225     brouard  8230:     
1.223     brouard  8231:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   8232:       cutv(stra, strb, line, ' '); 
                   8233:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  8234:        lval=-1;
1.223     brouard  8235:       }else{
1.225     brouard  8236:        errno=0;
                   8237:        /* what_kind_of_number(strb); */
                   8238:        dval=strtod(strb,&endptr);
                   8239:        /* if(strb != endptr && *endptr == '\0') */
                   8240:        /*   dval=dlval; */
                   8241:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8242:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8243:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   8244:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   8245:          return 1;
                   8246:        }
                   8247:        coqvar[iv][i]=dval; 
1.226     brouard  8248:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  8249:       }
                   8250:       strcpy(line,stra);
                   8251:     }/* end loop nqv */
1.136     brouard  8252:     
1.223     brouard  8253:     /* Covariate values */
1.136     brouard  8254:     for (j=ncovcol;j>=1;j--){
                   8255:       cutv(stra, strb,line,' '); 
1.223     brouard  8256:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  8257:        lval=-1;
1.136     brouard  8258:       }else{
1.225     brouard  8259:        errno=0;
                   8260:        lval=strtol(strb,&endptr,10); 
                   8261:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8262:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   8263:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   8264:          return 1;
                   8265:        }
1.136     brouard  8266:       }
                   8267:       if(lval <-1 || lval >1){
1.225     brouard  8268:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8269:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8270:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8271:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8272:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8273:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8274:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8275:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8276:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  8277:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8278:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8279:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8280:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8281:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8282:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8283:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8284:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8285:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  8286:        return 1;
1.136     brouard  8287:       }
                   8288:       covar[j][i]=(double)(lval);
                   8289:       strcpy(line,stra);
                   8290:     }  
                   8291:     lstra=strlen(stra);
1.225     brouard  8292:     
1.136     brouard  8293:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   8294:       stratrunc = &(stra[lstra-9]);
                   8295:       num[i]=atol(stratrunc);
                   8296:     }
                   8297:     else
                   8298:       num[i]=atol(stra);
                   8299:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   8300:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   8301:     
                   8302:     i=i+1;
                   8303:   } /* End loop reading  data */
1.225     brouard  8304:   
1.136     brouard  8305:   *imax=i-1; /* Number of individuals */
                   8306:   fclose(fic);
1.225     brouard  8307:   
1.136     brouard  8308:   return (0);
1.164     brouard  8309:   /* endread: */
1.225     brouard  8310:   printf("Exiting readdata: ");
                   8311:   fclose(fic);
                   8312:   return (1);
1.223     brouard  8313: }
1.126     brouard  8314: 
1.234     brouard  8315: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  8316:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  8317:   while (*p2 == ' ')
1.234     brouard  8318:     p2++; 
                   8319:   /* while ((*p1++ = *p2++) !=0) */
                   8320:   /*   ; */
                   8321:   /* do */
                   8322:   /*   while (*p2 == ' ') */
                   8323:   /*     p2++; */
                   8324:   /* while (*p1++ == *p2++); */
                   8325:   *stri=p2; 
1.145     brouard  8326: }
                   8327: 
1.235     brouard  8328: int decoderesult ( char resultline[], int nres)
1.230     brouard  8329: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   8330: {
1.235     brouard  8331:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  8332:   char resultsav[MAXLINE];
1.234     brouard  8333:   int resultmodel[MAXLINE];
                   8334:   int modelresult[MAXLINE];
1.230     brouard  8335:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   8336: 
1.234     brouard  8337:   removefirstspace(&resultline);
1.233     brouard  8338:   printf("decoderesult:%s\n",resultline);
1.230     brouard  8339: 
                   8340:   if (strstr(resultline,"v") !=0){
                   8341:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   8342:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   8343:     return 1;
                   8344:   }
                   8345:   trimbb(resultsav, resultline);
                   8346:   if (strlen(resultsav) >1){
                   8347:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   8348:   }
1.234     brouard  8349:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   8350:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8351:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8352:   }
                   8353:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   8354:     if(nbocc(resultsav,'=') >1){
                   8355:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   8356:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   8357:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   8358:     }else
                   8359:       cutl(strc,strd,resultsav,'=');
1.230     brouard  8360:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  8361:     
1.230     brouard  8362:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   8363:     Tvarsel[k]=atoi(strc);
                   8364:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   8365:     /* cptcovsel++;     */
                   8366:     if (nbocc(stra,'=') >0)
                   8367:       strcpy(resultsav,stra); /* and analyzes it */
                   8368:   }
1.235     brouard  8369:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  8370:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8371:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  8372:       match=0;
1.236     brouard  8373:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  8374:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  8375:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  8376:          match=1;
                   8377:          break;
                   8378:        }
                   8379:       }
                   8380:       if(match == 0){
                   8381:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8382:       }
                   8383:     }
                   8384:   }
1.235     brouard  8385:   /* Checking for missing or useless values in comparison of current model needs */
                   8386:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  8387:     match=0;
1.235     brouard  8388:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8389:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  8390:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  8391:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  8392:          ++match;
                   8393:        }
                   8394:       }
                   8395:     }
                   8396:     if(match == 0){
                   8397:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8398:     }else if(match > 1){
                   8399:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   8400:     }
                   8401:   }
1.235     brouard  8402:       
1.234     brouard  8403:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  8404:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8405:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   8406:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   8407:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   8408:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   8409:   /*    1 0 0 0 */
                   8410:   /*    2 1 0 0 */
                   8411:   /*    3 0 1 0 */ 
                   8412:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   8413:   /*    5 0 0 1 */
                   8414:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   8415:   /*    7 0 1 1 */
                   8416:   /*    8 1 1 1 */
1.237     brouard  8417:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   8418:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   8419:   /* V5*age V5 known which value for nres?  */
                   8420:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  8421:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   8422:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  8423:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  8424:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   8425:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  8426:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   8427:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   8428:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  8429:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   8430:       k4++;;
                   8431:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   8432:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   8433:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  8434:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   8435:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   8436:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  8437:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   8438:       k4q++;;
                   8439:     }
                   8440:   }
1.234     brouard  8441:   
1.235     brouard  8442:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  8443:   return (0);
                   8444: }
1.235     brouard  8445: 
1.230     brouard  8446: int decodemodel( char model[], int lastobs)
                   8447:  /**< This routine decodes the model and returns:
1.224     brouard  8448:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   8449:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   8450:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   8451:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   8452:        * - cptcovage number of covariates with age*products =2
                   8453:        * - cptcovs number of simple covariates
                   8454:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   8455:        *     which is a new column after the 9 (ncovcol) variables. 
                   8456:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   8457:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   8458:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   8459:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   8460:        */
1.136     brouard  8461: {
1.238     brouard  8462:   int i, j, k, ks, v;
1.227     brouard  8463:   int  j1, k1, k2, k3, k4;
1.136     brouard  8464:   char modelsav[80];
1.145     brouard  8465:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  8466:   char *strpt;
1.136     brouard  8467: 
1.145     brouard  8468:   /*removespace(model);*/
1.136     brouard  8469:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  8470:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  8471:     if (strstr(model,"AGE") !=0){
1.192     brouard  8472:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   8473:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  8474:       return 1;
                   8475:     }
1.141     brouard  8476:     if (strstr(model,"v") !=0){
                   8477:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   8478:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   8479:       return 1;
                   8480:     }
1.187     brouard  8481:     strcpy(modelsav,model); 
                   8482:     if ((strpt=strstr(model,"age*age")) !=0){
                   8483:       printf(" strpt=%s, model=%s\n",strpt, model);
                   8484:       if(strpt != model){
1.234     brouard  8485:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8486:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8487:  corresponding column of parameters.\n",model);
1.234     brouard  8488:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8489:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8490:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  8491:        return 1;
1.225     brouard  8492:       }
1.187     brouard  8493:       nagesqr=1;
                   8494:       if (strstr(model,"+age*age") !=0)
1.234     brouard  8495:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  8496:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  8497:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  8498:       else 
1.234     brouard  8499:        substrchaine(modelsav, model, "age*age");
1.187     brouard  8500:     }else
                   8501:       nagesqr=0;
                   8502:     if (strlen(modelsav) >1){
                   8503:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   8504:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  8505:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  8506:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  8507:                     * cst, age and age*age 
                   8508:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   8509:       /* including age products which are counted in cptcovage.
                   8510:        * but the covariates which are products must be treated 
                   8511:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  8512:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   8513:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  8514:       
                   8515:       
1.187     brouard  8516:       /*   Design
                   8517:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   8518:        *  <          ncovcol=8                >
                   8519:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   8520:        *   k=  1    2      3       4     5       6      7        8
                   8521:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   8522:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  8523:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   8524:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  8525:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   8526:        *  Tage[++cptcovage]=k
                   8527:        *       if products, new covar are created after ncovcol with k1
                   8528:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   8529:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   8530:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   8531:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   8532:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   8533:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   8534:        *  <          ncovcol=8                >
                   8535:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   8536:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   8537:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   8538:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8539:        * p Tprod[1]@2={                         6, 5}
                   8540:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   8541:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   8542:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   8543:        *How to reorganize?
                   8544:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   8545:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8546:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   8547:        * Struct []
                   8548:        */
1.225     brouard  8549:       
1.187     brouard  8550:       /* This loop fills the array Tvar from the string 'model'.*/
                   8551:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   8552:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   8553:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   8554:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   8555:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   8556:       /*       k=1 Tvar[1]=2 (from V2) */
                   8557:       /*       k=5 Tvar[5] */
                   8558:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  8559:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  8560:       /*       } */
1.198     brouard  8561:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  8562:       /*
                   8563:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  8564:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   8565:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   8566:       }
1.187     brouard  8567:       cptcovage=0;
                   8568:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  8569:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  8570:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  8571:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   8572:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   8573:        /*scanf("%d",i);*/
                   8574:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   8575:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   8576:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   8577:            /* covar is not filled and then is empty */
                   8578:            cptcovprod--;
                   8579:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   8580:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   8581:            Typevar[k]=1;  /* 1 for age product */
                   8582:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   8583:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   8584:            /*printf("stre=%s ", stre);*/
                   8585:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   8586:            cptcovprod--;
                   8587:            cutl(stre,strb,strc,'V');
                   8588:            Tvar[k]=atoi(stre);
                   8589:            Typevar[k]=1;  /* 1 for age product */
                   8590:            cptcovage++;
                   8591:            Tage[cptcovage]=k;
                   8592:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   8593:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   8594:            cptcovn++;
                   8595:            cptcovprodnoage++;k1++;
                   8596:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   8597:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   8598:                                                because this model-covariate is a construction we invent a new column
                   8599:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   8600:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   8601:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   8602:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   8603:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   8604:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   8605:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   8606:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   8607:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   8608:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   8609:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   8610:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  8611:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  8612:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   8613:            for (i=1; i<=lastobs;i++){
                   8614:              /* Computes the new covariate which is a product of
                   8615:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   8616:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   8617:            }
                   8618:          } /* End age is not in the model */
                   8619:        } /* End if model includes a product */
                   8620:        else { /* no more sum */
                   8621:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   8622:          /*  scanf("%d",i);*/
                   8623:          cutl(strd,strc,strb,'V');
                   8624:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   8625:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   8626:          Tvar[k]=atoi(strd);
                   8627:          Typevar[k]=0;  /* 0 for simple covariates */
                   8628:        }
                   8629:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  8630:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  8631:                                  scanf("%d",i);*/
1.187     brouard  8632:       } /* end of loop + on total covariates */
                   8633:     } /* end if strlen(modelsave == 0) age*age might exist */
                   8634:   } /* end if strlen(model == 0) */
1.136     brouard  8635:   
                   8636:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   8637:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  8638:   
1.136     brouard  8639:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  8640:      printf("cptcovprod=%d ", cptcovprod);
                   8641:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   8642:      scanf("%d ",i);*/
                   8643: 
                   8644: 
1.230     brouard  8645: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   8646:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  8647: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   8648:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   8649:    k =           1    2   3     4       5       6      7      8        9
                   8650:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   8651:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  8652:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   8653:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   8654:          Tmodelind[combination of covar]=k;
1.225     brouard  8655: */  
                   8656: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  8657:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  8658:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  8659:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  8660:   printf("Model=%s\n\
                   8661: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8662: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8663: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8664:   fprintf(ficlog,"Model=%s\n\
                   8665: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8666: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8667: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  8668:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  8669:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   8670:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  8671:       Fixed[k]= 0;
                   8672:       Dummy[k]= 0;
1.225     brouard  8673:       ncoveff++;
1.232     brouard  8674:       ncovf++;
1.234     brouard  8675:       nsd++;
                   8676:       modell[k].maintype= FTYPE;
                   8677:       TvarsD[nsd]=Tvar[k];
                   8678:       TvarsDind[nsd]=k;
                   8679:       TvarF[ncovf]=Tvar[k];
                   8680:       TvarFind[ncovf]=k;
                   8681:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8682:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8683:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   8684:       Fixed[k]= 0;
                   8685:       Dummy[k]= 0;
                   8686:       ncoveff++;
                   8687:       ncovf++;
                   8688:       modell[k].maintype= FTYPE;
                   8689:       TvarF[ncovf]=Tvar[k];
                   8690:       TvarFind[ncovf]=k;
1.230     brouard  8691:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  8692:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  8693:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  8694:       Fixed[k]= 0;
                   8695:       Dummy[k]= 1;
1.230     brouard  8696:       nqfveff++;
1.234     brouard  8697:       modell[k].maintype= FTYPE;
                   8698:       modell[k].subtype= FQ;
                   8699:       nsq++;
                   8700:       TvarsQ[nsq]=Tvar[k];
                   8701:       TvarsQind[nsq]=k;
1.232     brouard  8702:       ncovf++;
1.234     brouard  8703:       TvarF[ncovf]=Tvar[k];
                   8704:       TvarFind[ncovf]=k;
1.231     brouard  8705:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  8706:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  8707:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  8708:       Fixed[k]= 1;
                   8709:       Dummy[k]= 0;
1.225     brouard  8710:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  8711:       modell[k].maintype= VTYPE;
                   8712:       modell[k].subtype= VD;
                   8713:       nsd++;
                   8714:       TvarsD[nsd]=Tvar[k];
                   8715:       TvarsDind[nsd]=k;
                   8716:       ncovv++; /* Only simple time varying variables */
                   8717:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8718:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8719:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   8720:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  8721:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   8722:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  8723:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  8724:       Fixed[k]= 1;
                   8725:       Dummy[k]= 1;
                   8726:       nqtveff++;
                   8727:       modell[k].maintype= VTYPE;
                   8728:       modell[k].subtype= VQ;
                   8729:       ncovv++; /* Only simple time varying variables */
                   8730:       nsq++;
                   8731:       TvarsQ[nsq]=Tvar[k];
                   8732:       TvarsQind[nsq]=k;
                   8733:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8734:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8735:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   8736:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  8737:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   8738:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   8739:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  8740:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  8741:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  8742:       ncova++;
                   8743:       TvarA[ncova]=Tvar[k];
                   8744:       TvarAind[ncova]=k;
1.231     brouard  8745:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  8746:        Fixed[k]= 2;
                   8747:        Dummy[k]= 2;
                   8748:        modell[k].maintype= ATYPE;
                   8749:        modell[k].subtype= APFD;
                   8750:        /* ncoveff++; */
1.227     brouard  8751:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  8752:        Fixed[k]= 2;
                   8753:        Dummy[k]= 3;
                   8754:        modell[k].maintype= ATYPE;
                   8755:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   8756:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  8757:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  8758:        Fixed[k]= 3;
                   8759:        Dummy[k]= 2;
                   8760:        modell[k].maintype= ATYPE;
                   8761:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   8762:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  8763:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  8764:        Fixed[k]= 3;
                   8765:        Dummy[k]= 3;
                   8766:        modell[k].maintype= ATYPE;
                   8767:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   8768:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  8769:       }
                   8770:     }else if (Typevar[k] == 2) {  /* product without age */
                   8771:       k1=Tposprod[k];
                   8772:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  8773:        if(Tvard[k1][2] <=ncovcol){
                   8774:          Fixed[k]= 1;
                   8775:          Dummy[k]= 0;
                   8776:          modell[k].maintype= FTYPE;
                   8777:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   8778:          ncovf++; /* Fixed variables without age */
                   8779:          TvarF[ncovf]=Tvar[k];
                   8780:          TvarFind[ncovf]=k;
                   8781:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8782:          Fixed[k]= 0;  /* or 2 ?*/
                   8783:          Dummy[k]= 1;
                   8784:          modell[k].maintype= FTYPE;
                   8785:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   8786:          ncovf++; /* Varying variables without age */
                   8787:          TvarF[ncovf]=Tvar[k];
                   8788:          TvarFind[ncovf]=k;
                   8789:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8790:          Fixed[k]= 1;
                   8791:          Dummy[k]= 0;
                   8792:          modell[k].maintype= VTYPE;
                   8793:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   8794:          ncovv++; /* Varying variables without age */
                   8795:          TvarV[ncovv]=Tvar[k];
                   8796:          TvarVind[ncovv]=k;
                   8797:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8798:          Fixed[k]= 1;
                   8799:          Dummy[k]= 1;
                   8800:          modell[k].maintype= VTYPE;
                   8801:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   8802:          ncovv++; /* Varying variables without age */
                   8803:          TvarV[ncovv]=Tvar[k];
                   8804:          TvarVind[ncovv]=k;
                   8805:        }
1.227     brouard  8806:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  8807:        if(Tvard[k1][2] <=ncovcol){
                   8808:          Fixed[k]= 0;  /* or 2 ?*/
                   8809:          Dummy[k]= 1;
                   8810:          modell[k].maintype= FTYPE;
                   8811:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   8812:          ncovf++; /* Fixed variables without age */
                   8813:          TvarF[ncovf]=Tvar[k];
                   8814:          TvarFind[ncovf]=k;
                   8815:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8816:          Fixed[k]= 1;
                   8817:          Dummy[k]= 1;
                   8818:          modell[k].maintype= VTYPE;
                   8819:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   8820:          ncovv++; /* Varying variables without age */
                   8821:          TvarV[ncovv]=Tvar[k];
                   8822:          TvarVind[ncovv]=k;
                   8823:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8824:          Fixed[k]= 1;
                   8825:          Dummy[k]= 1;
                   8826:          modell[k].maintype= VTYPE;
                   8827:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   8828:          ncovv++; /* Varying variables without age */
                   8829:          TvarV[ncovv]=Tvar[k];
                   8830:          TvarVind[ncovv]=k;
                   8831:          ncovv++; /* Varying variables without age */
                   8832:          TvarV[ncovv]=Tvar[k];
                   8833:          TvarVind[ncovv]=k;
                   8834:        }
1.227     brouard  8835:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  8836:        if(Tvard[k1][2] <=ncovcol){
                   8837:          Fixed[k]= 1;
                   8838:          Dummy[k]= 1;
                   8839:          modell[k].maintype= VTYPE;
                   8840:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   8841:          ncovv++; /* Varying variables without age */
                   8842:          TvarV[ncovv]=Tvar[k];
                   8843:          TvarVind[ncovv]=k;
                   8844:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8845:          Fixed[k]= 1;
                   8846:          Dummy[k]= 1;
                   8847:          modell[k].maintype= VTYPE;
                   8848:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   8849:          ncovv++; /* Varying variables without age */
                   8850:          TvarV[ncovv]=Tvar[k];
                   8851:          TvarVind[ncovv]=k;
                   8852:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8853:          Fixed[k]= 1;
                   8854:          Dummy[k]= 0;
                   8855:          modell[k].maintype= VTYPE;
                   8856:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   8857:          ncovv++; /* Varying variables without age */
                   8858:          TvarV[ncovv]=Tvar[k];
                   8859:          TvarVind[ncovv]=k;
                   8860:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8861:          Fixed[k]= 1;
                   8862:          Dummy[k]= 1;
                   8863:          modell[k].maintype= VTYPE;
                   8864:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   8865:          ncovv++; /* Varying variables without age */
                   8866:          TvarV[ncovv]=Tvar[k];
                   8867:          TvarVind[ncovv]=k;
                   8868:        }
1.227     brouard  8869:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  8870:        if(Tvard[k1][2] <=ncovcol){
                   8871:          Fixed[k]= 1;
                   8872:          Dummy[k]= 1;
                   8873:          modell[k].maintype= VTYPE;
                   8874:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   8875:          ncovv++; /* Varying variables without age */
                   8876:          TvarV[ncovv]=Tvar[k];
                   8877:          TvarVind[ncovv]=k;
                   8878:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8879:          Fixed[k]= 1;
                   8880:          Dummy[k]= 1;
                   8881:          modell[k].maintype= VTYPE;
                   8882:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   8883:          ncovv++; /* Varying variables without age */
                   8884:          TvarV[ncovv]=Tvar[k];
                   8885:          TvarVind[ncovv]=k;
                   8886:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8887:          Fixed[k]= 1;
                   8888:          Dummy[k]= 1;
                   8889:          modell[k].maintype= VTYPE;
                   8890:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   8891:          ncovv++; /* Varying variables without age */
                   8892:          TvarV[ncovv]=Tvar[k];
                   8893:          TvarVind[ncovv]=k;
                   8894:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8895:          Fixed[k]= 1;
                   8896:          Dummy[k]= 1;
                   8897:          modell[k].maintype= VTYPE;
                   8898:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   8899:          ncovv++; /* Varying variables without age */
                   8900:          TvarV[ncovv]=Tvar[k];
                   8901:          TvarVind[ncovv]=k;
                   8902:        }
1.227     brouard  8903:       }else{
1.240     brouard  8904:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   8905:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   8906:       } /*end k1*/
1.225     brouard  8907:     }else{
1.226     brouard  8908:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   8909:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  8910:     }
1.227     brouard  8911:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  8912:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  8913:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   8914:   }
                   8915:   /* Searching for doublons in the model */
                   8916:   for(k1=1; k1<= cptcovt;k1++){
                   8917:     for(k2=1; k2 <k1;k2++){
                   8918:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  8919:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   8920:          if(Tvar[k1]==Tvar[k2]){
                   8921:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   8922:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   8923:            return(1);
                   8924:          }
                   8925:        }else if (Typevar[k1] ==2){
                   8926:          k3=Tposprod[k1];
                   8927:          k4=Tposprod[k2];
                   8928:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   8929:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   8930:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   8931:            return(1);
                   8932:          }
                   8933:        }
1.227     brouard  8934:       }
                   8935:     }
1.225     brouard  8936:   }
                   8937:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   8938:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  8939:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   8940:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  8941:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  8942:   /*endread:*/
1.225     brouard  8943:   printf("Exiting decodemodel: ");
                   8944:   return (1);
1.136     brouard  8945: }
                   8946: 
1.169     brouard  8947: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  8948: {/* Check ages at death */
1.136     brouard  8949:   int i, m;
1.218     brouard  8950:   int firstone=0;
                   8951:   
1.136     brouard  8952:   for (i=1; i<=imx; i++) {
                   8953:     for(m=2; (m<= maxwav); m++) {
                   8954:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   8955:        anint[m][i]=9999;
1.216     brouard  8956:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   8957:          s[m][i]=-1;
1.136     brouard  8958:       }
                   8959:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.169     brouard  8960:        *nberr = *nberr + 1;
1.218     brouard  8961:        if(firstone == 0){
                   8962:          firstone=1;
                   8963:        printf("Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\nOther similar cases in log file\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
                   8964:        }
                   8965:        fprintf(ficlog,"Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
1.136     brouard  8966:        s[m][i]=-1;
                   8967:       }
                   8968:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  8969:        (*nberr)++;
1.136     brouard  8970:        printf("Error! Month of death of individual %ld on line %d was unknown %2d, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,(int)moisdc[i]); 
                   8971:        fprintf(ficlog,"Error! Month of death of individual %ld on line %d was unknown %f, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,moisdc[i]); 
                   8972:        s[m][i]=-1; /* We prefer to skip it (and to skip it in version 0.8a1 too */
                   8973:       }
                   8974:     }
                   8975:   }
                   8976: 
                   8977:   for (i=1; i<=imx; i++)  {
                   8978:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   8979:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  8980:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  8981:        if (s[m][i] >= nlstate+1) {
1.169     brouard  8982:          if(agedc[i]>0){
                   8983:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  8984:              agev[m][i]=agedc[i];
1.214     brouard  8985:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  8986:            }else {
1.136     brouard  8987:              if ((int)andc[i]!=9999){
                   8988:                nbwarn++;
                   8989:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   8990:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   8991:                agev[m][i]=-1;
                   8992:              }
                   8993:            }
1.169     brouard  8994:          } /* agedc > 0 */
1.214     brouard  8995:        } /* end if */
1.136     brouard  8996:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   8997:                                 years but with the precision of a month */
                   8998:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   8999:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   9000:            agev[m][i]=1;
                   9001:          else if(agev[m][i] < *agemin){ 
                   9002:            *agemin=agev[m][i];
                   9003:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   9004:          }
                   9005:          else if(agev[m][i] >*agemax){
                   9006:            *agemax=agev[m][i];
1.156     brouard  9007:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  9008:          }
                   9009:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   9010:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  9011:        } /* en if 9*/
1.136     brouard  9012:        else { /* =9 */
1.214     brouard  9013:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  9014:          agev[m][i]=1;
                   9015:          s[m][i]=-1;
                   9016:        }
                   9017:       }
1.214     brouard  9018:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  9019:        agev[m][i]=1;
1.214     brouard  9020:       else{
                   9021:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9022:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9023:        agev[m][i]=0;
                   9024:       }
                   9025:     } /* End for lastpass */
                   9026:   }
1.136     brouard  9027:     
                   9028:   for (i=1; i<=imx; i++)  {
                   9029:     for(m=firstpass; (m<=lastpass); m++){
                   9030:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  9031:        (*nberr)++;
1.136     brouard  9032:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9033:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9034:        return 1;
                   9035:       }
                   9036:     }
                   9037:   }
                   9038: 
                   9039:   /*for (i=1; i<=imx; i++){
                   9040:   for (m=firstpass; (m<lastpass); m++){
                   9041:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   9042: }
                   9043: 
                   9044: }*/
                   9045: 
                   9046: 
1.139     brouard  9047:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   9048:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  9049: 
                   9050:   return (0);
1.164     brouard  9051:  /* endread:*/
1.136     brouard  9052:     printf("Exiting calandcheckages: ");
                   9053:     return (1);
                   9054: }
                   9055: 
1.172     brouard  9056: #if defined(_MSC_VER)
                   9057: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9058: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9059: //#include "stdafx.h"
                   9060: //#include <stdio.h>
                   9061: //#include <tchar.h>
                   9062: //#include <windows.h>
                   9063: //#include <iostream>
                   9064: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   9065: 
                   9066: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9067: 
                   9068: BOOL IsWow64()
                   9069: {
                   9070:        BOOL bIsWow64 = FALSE;
                   9071: 
                   9072:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   9073:        //  (HANDLE, PBOOL);
                   9074: 
                   9075:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9076: 
                   9077:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   9078:        const char funcName[] = "IsWow64Process";
                   9079:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   9080:                GetProcAddress(module, funcName);
                   9081: 
                   9082:        if (NULL != fnIsWow64Process)
                   9083:        {
                   9084:                if (!fnIsWow64Process(GetCurrentProcess(),
                   9085:                        &bIsWow64))
                   9086:                        //throw std::exception("Unknown error");
                   9087:                        printf("Unknown error\n");
                   9088:        }
                   9089:        return bIsWow64 != FALSE;
                   9090: }
                   9091: #endif
1.177     brouard  9092: 
1.191     brouard  9093: void syscompilerinfo(int logged)
1.167     brouard  9094:  {
                   9095:    /* #include "syscompilerinfo.h"*/
1.185     brouard  9096:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   9097:    /* /GS /W3 /Gy
                   9098:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   9099:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   9100:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  9101:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   9102:    */ 
                   9103:    /* 64 bits */
1.185     brouard  9104:    /*
                   9105:      /GS /W3 /Gy
                   9106:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   9107:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   9108:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   9109:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   9110:    /* Optimization are useless and O3 is slower than O2 */
                   9111:    /*
                   9112:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   9113:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   9114:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   9115:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   9116:    */
1.186     brouard  9117:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  9118:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   9119:       /PDB:"visual studio
                   9120:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   9121:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   9122:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   9123:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   9124:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   9125:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   9126:       uiAccess='false'"
                   9127:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   9128:       /NOLOGO /TLBID:1
                   9129:    */
1.177     brouard  9130: #if defined __INTEL_COMPILER
1.178     brouard  9131: #if defined(__GNUC__)
                   9132:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   9133: #endif
1.177     brouard  9134: #elif defined(__GNUC__) 
1.179     brouard  9135: #ifndef  __APPLE__
1.174     brouard  9136: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  9137: #endif
1.177     brouard  9138:    struct utsname sysInfo;
1.178     brouard  9139:    int cross = CROSS;
                   9140:    if (cross){
                   9141:           printf("Cross-");
1.191     brouard  9142:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  9143:    }
1.174     brouard  9144: #endif
                   9145: 
1.171     brouard  9146: #include <stdint.h>
1.178     brouard  9147: 
1.191     brouard  9148:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  9149: #if defined(__clang__)
1.191     brouard  9150:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  9151: #endif
                   9152: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  9153:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  9154: #endif
                   9155: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  9156:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  9157: #endif
                   9158: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  9159:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  9160: #endif
                   9161: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  9162:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  9163: #endif
                   9164: #if defined(_MSC_VER)
1.191     brouard  9165:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  9166: #endif
                   9167: #if defined(__PGI)
1.191     brouard  9168:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  9169: #endif
                   9170: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  9171:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  9172: #endif
1.191     brouard  9173:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  9174:    
1.167     brouard  9175: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   9176: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   9177:     // Windows (x64 and x86)
1.191     brouard  9178:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  9179: #elif __unix__ // all unices, not all compilers
                   9180:     // Unix
1.191     brouard  9181:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  9182: #elif __linux__
                   9183:     // linux
1.191     brouard  9184:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  9185: #elif __APPLE__
1.174     brouard  9186:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  9187:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  9188: #endif
                   9189: 
                   9190: /*  __MINGW32__          */
                   9191: /*  __CYGWIN__  */
                   9192: /* __MINGW64__  */
                   9193: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   9194: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   9195: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   9196: /* _WIN64  // Defined for applications for Win64. */
                   9197: /* _M_X64 // Defined for compilations that target x64 processors. */
                   9198: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  9199: 
1.167     brouard  9200: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  9201:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  9202: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  9203:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  9204: #else
1.191     brouard  9205:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  9206: #endif
                   9207: 
1.169     brouard  9208: #if defined(__GNUC__)
                   9209: # if defined(__GNUC_PATCHLEVEL__)
                   9210: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9211:                             + __GNUC_MINOR__ * 100 \
                   9212:                             + __GNUC_PATCHLEVEL__)
                   9213: # else
                   9214: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9215:                             + __GNUC_MINOR__ * 100)
                   9216: # endif
1.174     brouard  9217:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  9218:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  9219: 
                   9220:    if (uname(&sysInfo) != -1) {
                   9221:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  9222:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  9223:    }
                   9224:    else
                   9225:       perror("uname() error");
1.179     brouard  9226:    //#ifndef __INTEL_COMPILER 
                   9227: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  9228:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  9229:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  9230: #endif
1.169     brouard  9231: #endif
1.172     brouard  9232: 
                   9233:    //   void main()
                   9234:    //   {
1.169     brouard  9235: #if defined(_MSC_VER)
1.174     brouard  9236:    if (IsWow64()){
1.191     brouard  9237:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   9238:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  9239:    }
                   9240:    else{
1.191     brouard  9241:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   9242:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  9243:    }
1.172     brouard  9244:    //     printf("\nPress Enter to continue...");
                   9245:    //     getchar();
                   9246:    //   }
                   9247: 
1.169     brouard  9248: #endif
                   9249:    
1.167     brouard  9250: 
1.219     brouard  9251: }
1.136     brouard  9252: 
1.219     brouard  9253: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  9254:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  9255:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  9256:   /* double ftolpl = 1.e-10; */
1.180     brouard  9257:   double age, agebase, agelim;
1.203     brouard  9258:   double tot;
1.180     brouard  9259: 
1.202     brouard  9260:   strcpy(filerespl,"PL_");
                   9261:   strcat(filerespl,fileresu);
                   9262:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   9263:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9264:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9265:   }
1.227     brouard  9266:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   9267:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  9268:   pstamp(ficrespl);
1.203     brouard  9269:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  9270:   fprintf(ficrespl,"#Age ");
                   9271:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   9272:   fprintf(ficrespl,"\n");
1.180     brouard  9273:   
1.219     brouard  9274:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  9275: 
1.219     brouard  9276:   agebase=ageminpar;
                   9277:   agelim=agemaxpar;
1.180     brouard  9278: 
1.227     brouard  9279:   /* i1=pow(2,ncoveff); */
1.234     brouard  9280:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  9281:   if (cptcovn < 1){i1=1;}
1.180     brouard  9282: 
1.238     brouard  9283:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   9284:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9285:       if(TKresult[nres]!= k)
                   9286:        continue;
1.235     brouard  9287: 
1.238     brouard  9288:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9289:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   9290:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   9291:       /* k=k+1; */
                   9292:       /* to clean */
                   9293:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9294:       fprintf(ficrespl,"#******");
                   9295:       printf("#******");
                   9296:       fprintf(ficlog,"#******");
                   9297:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9298:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   9299:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9300:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9301:       }
                   9302:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9303:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9304:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9305:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9306:       }
                   9307:       fprintf(ficrespl,"******\n");
                   9308:       printf("******\n");
                   9309:       fprintf(ficlog,"******\n");
                   9310:       if(invalidvarcomb[k]){
                   9311:        printf("\nCombination (%d) ignored because no case \n",k); 
                   9312:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   9313:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   9314:        continue;
                   9315:       }
1.219     brouard  9316: 
1.238     brouard  9317:       fprintf(ficrespl,"#Age ");
                   9318:       for(j=1;j<=cptcoveff;j++) {
                   9319:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9320:       }
                   9321:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   9322:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  9323:     
1.238     brouard  9324:       for (age=agebase; age<=agelim; age++){
                   9325:        /* for (age=agebase; age<=agebase; age++){ */
                   9326:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   9327:        fprintf(ficrespl,"%.0f ",age );
                   9328:        for(j=1;j<=cptcoveff;j++)
                   9329:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9330:        tot=0.;
                   9331:        for(i=1; i<=nlstate;i++){
                   9332:          tot +=  prlim[i][i];
                   9333:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   9334:        }
                   9335:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   9336:       } /* Age */
                   9337:       /* was end of cptcod */
                   9338:     } /* cptcov */
                   9339:   } /* nres */
1.219     brouard  9340:   return 0;
1.180     brouard  9341: }
                   9342: 
1.218     brouard  9343: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   9344:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   9345:        
                   9346:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   9347:    * at any age between ageminpar and agemaxpar
                   9348:         */
1.235     brouard  9349:   int i, j, k, i1, nres=0 ;
1.217     brouard  9350:   /* double ftolpl = 1.e-10; */
                   9351:   double age, agebase, agelim;
                   9352:   double tot;
1.218     brouard  9353:   /* double ***mobaverage; */
                   9354:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  9355: 
                   9356:   strcpy(fileresplb,"PLB_");
                   9357:   strcat(fileresplb,fileresu);
                   9358:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   9359:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9360:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9361:   }
                   9362:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9363:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9364:   pstamp(ficresplb);
                   9365:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   9366:   fprintf(ficresplb,"#Age ");
                   9367:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   9368:   fprintf(ficresplb,"\n");
                   9369:   
1.218     brouard  9370:   
                   9371:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   9372:   
                   9373:   agebase=ageminpar;
                   9374:   agelim=agemaxpar;
                   9375:   
                   9376:   
1.227     brouard  9377:   i1=pow(2,cptcoveff);
1.218     brouard  9378:   if (cptcovn < 1){i1=1;}
1.227     brouard  9379:   
1.238     brouard  9380:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9381:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
                   9382:       if(TKresult[nres]!= k)
                   9383:        continue;
                   9384:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9385:       fprintf(ficresplb,"#******");
                   9386:       printf("#******");
                   9387:       fprintf(ficlog,"#******");
                   9388:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9389:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9390:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9391:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9392:       }
                   9393:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9394:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9395:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9396:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9397:       }
                   9398:       fprintf(ficresplb,"******\n");
                   9399:       printf("******\n");
                   9400:       fprintf(ficlog,"******\n");
                   9401:       if(invalidvarcomb[k]){
                   9402:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   9403:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   9404:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   9405:        continue;
                   9406:       }
1.218     brouard  9407:     
1.238     brouard  9408:       fprintf(ficresplb,"#Age ");
                   9409:       for(j=1;j<=cptcoveff;j++) {
                   9410:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9411:       }
                   9412:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   9413:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  9414:     
                   9415:     
1.238     brouard  9416:       for (age=agebase; age<=agelim; age++){
                   9417:        /* for (age=agebase; age<=agebase; age++){ */
                   9418:        if(mobilavproj > 0){
                   9419:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   9420:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9421:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  9422:        }else if (mobilavproj == 0){
                   9423:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9424:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9425:          exit(1);
                   9426:        }else{
                   9427:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9428:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.238     brouard  9429:        }
                   9430:        fprintf(ficresplb,"%.0f ",age );
                   9431:        for(j=1;j<=cptcoveff;j++)
                   9432:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9433:        tot=0.;
                   9434:        for(i=1; i<=nlstate;i++){
                   9435:          tot +=  bprlim[i][i];
                   9436:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   9437:        }
                   9438:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   9439:       } /* Age */
                   9440:       /* was end of cptcod */
                   9441:     } /* end of any combination */
                   9442:   } /* end of nres */  
1.218     brouard  9443:   /* hBijx(p, bage, fage); */
                   9444:   /* fclose(ficrespijb); */
                   9445:   
                   9446:   return 0;
1.217     brouard  9447: }
1.218     brouard  9448:  
1.180     brouard  9449: int hPijx(double *p, int bage, int fage){
                   9450:     /*------------- h Pij x at various ages ------------*/
                   9451: 
                   9452:   int stepsize;
                   9453:   int agelim;
                   9454:   int hstepm;
                   9455:   int nhstepm;
1.235     brouard  9456:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  9457: 
                   9458:   double agedeb;
                   9459:   double ***p3mat;
                   9460: 
1.201     brouard  9461:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  9462:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   9463:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9464:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9465:     }
                   9466:     printf("Computing pij: result on file '%s' \n", filerespij);
                   9467:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   9468:   
                   9469:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9470:     /*if (stepm<=24) stepsize=2;*/
                   9471: 
                   9472:     agelim=AGESUP;
                   9473:     hstepm=stepsize*YEARM; /* Every year of age */
                   9474:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  9475:                
1.180     brouard  9476:     /* hstepm=1;   aff par mois*/
                   9477:     pstamp(ficrespij);
                   9478:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  9479:     i1= pow(2,cptcoveff);
1.218     brouard  9480:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9481:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9482:                /*      k=k+1;  */
1.235     brouard  9483:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9484:     for(k=1; k<=i1;k++){
                   9485:       if(TKresult[nres]!= k)
                   9486:        continue;
1.183     brouard  9487:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  9488:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  9489:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  9490:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9491:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9492:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9493:       }
1.183     brouard  9494:       fprintf(ficrespij,"******\n");
                   9495:       
                   9496:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   9497:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   9498:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   9499:        
                   9500:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  9501:        
1.183     brouard  9502:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9503:        oldm=oldms;savm=savms;
1.235     brouard  9504:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  9505:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   9506:        for(i=1; i<=nlstate;i++)
                   9507:          for(j=1; j<=nlstate+ndeath;j++)
                   9508:            fprintf(ficrespij," %1d-%1d",i,j);
                   9509:        fprintf(ficrespij,"\n");
                   9510:        for (h=0; h<=nhstepm; h++){
                   9511:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9512:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  9513:          for(i=1; i<=nlstate;i++)
                   9514:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  9515:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  9516:          fprintf(ficrespij,"\n");
                   9517:        }
1.183     brouard  9518:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9519:        fprintf(ficrespij,"\n");
                   9520:       }
1.180     brouard  9521:       /*}*/
                   9522:     }
1.218     brouard  9523:     return 0;
1.180     brouard  9524: }
1.218     brouard  9525:  
                   9526:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  9527:     /*------------- h Bij x at various ages ------------*/
                   9528: 
                   9529:   int stepsize;
1.218     brouard  9530:   /* int agelim; */
                   9531:        int ageminl;
1.217     brouard  9532:   int hstepm;
                   9533:   int nhstepm;
1.238     brouard  9534:   int h, i, i1, j, k, nres;
1.218     brouard  9535:        
1.217     brouard  9536:   double agedeb;
                   9537:   double ***p3mat;
1.218     brouard  9538:        
                   9539:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   9540:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   9541:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9542:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9543:   }
                   9544:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   9545:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   9546:   
                   9547:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9548:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  9549:   
1.218     brouard  9550:   /* agelim=AGESUP; */
                   9551:   ageminl=30;
                   9552:   hstepm=stepsize*YEARM; /* Every year of age */
                   9553:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   9554:   
                   9555:   /* hstepm=1;   aff par mois*/
                   9556:   pstamp(ficrespijb);
                   9557:   fprintf(ficrespijb,"#****** h Pij x Back Probability to be in state i at age x-h being in j at x ");
1.227     brouard  9558:   i1= pow(2,cptcoveff);
1.218     brouard  9559:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9560:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9561:   /*   k=k+1;  */
1.238     brouard  9562:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9563:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
                   9564:       if(TKresult[nres]!= k)
                   9565:        continue;
                   9566:       fprintf(ficrespijb,"\n#****** ");
                   9567:       for(j=1;j<=cptcoveff;j++)
                   9568:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9569:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9570:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9571:       }
                   9572:       fprintf(ficrespijb,"******\n");
                   9573:       if(invalidvarcomb[k]){
                   9574:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   9575:        continue;
                   9576:       }
                   9577:       
                   9578:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   9579:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   9580:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   9581:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   9582:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   9583:        
                   9584:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   9585:        
                   9586:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9587:        /* oldm=oldms;savm=savms; */
                   9588:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9589:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k);
                   9590:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
                   9591:        fprintf(ficrespijb,"# Cov Agex agex-h hpijx with i,j=");
1.217     brouard  9592:        for(i=1; i<=nlstate;i++)
                   9593:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  9594:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  9595:        fprintf(ficrespijb,"\n");
1.238     brouard  9596:        for (h=0; h<=nhstepm; h++){
                   9597:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9598:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   9599:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   9600:          for(i=1; i<=nlstate;i++)
                   9601:            for(j=1; j<=nlstate+ndeath;j++)
                   9602:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   9603:          fprintf(ficrespijb,"\n");
                   9604:        }
                   9605:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9606:        fprintf(ficrespijb,"\n");
                   9607:       } /* end age deb */
                   9608:     } /* end combination */
                   9609:   } /* end nres */
1.218     brouard  9610:   return 0;
                   9611:  } /*  hBijx */
1.217     brouard  9612: 
1.180     brouard  9613: 
1.136     brouard  9614: /***********************************************/
                   9615: /**************** Main Program *****************/
                   9616: /***********************************************/
                   9617: 
                   9618: int main(int argc, char *argv[])
                   9619: {
                   9620: #ifdef GSL
                   9621:   const gsl_multimin_fminimizer_type *T;
                   9622:   size_t iteri = 0, it;
                   9623:   int rval = GSL_CONTINUE;
                   9624:   int status = GSL_SUCCESS;
                   9625:   double ssval;
                   9626: #endif
                   9627:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  9628:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  9629:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  9630:   int jj, ll, li, lj, lk;
1.136     brouard  9631:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  9632:   int num_filled;
1.136     brouard  9633:   int itimes;
                   9634:   int NDIM=2;
                   9635:   int vpopbased=0;
1.235     brouard  9636:   int nres=0;
1.136     brouard  9637: 
1.164     brouard  9638:   char ca[32], cb[32];
1.136     brouard  9639:   /*  FILE *fichtm; *//* Html File */
                   9640:   /* FILE *ficgp;*/ /*Gnuplot File */
                   9641:   struct stat info;
1.191     brouard  9642:   double agedeb=0.;
1.194     brouard  9643: 
                   9644:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  9645:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  9646: 
1.165     brouard  9647:   double fret;
1.191     brouard  9648:   double dum=0.; /* Dummy variable */
1.136     brouard  9649:   double ***p3mat;
1.218     brouard  9650:   /* double ***mobaverage; */
1.164     brouard  9651: 
                   9652:   char line[MAXLINE];
1.197     brouard  9653:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   9654: 
1.234     brouard  9655:   char  modeltemp[MAXLINE];
1.230     brouard  9656:   char resultline[MAXLINE];
                   9657:   
1.136     brouard  9658:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  9659:   char *tok, *val; /* pathtot */
1.136     brouard  9660:   int firstobs=1, lastobs=10;
1.195     brouard  9661:   int c,  h , cpt, c2;
1.191     brouard  9662:   int jl=0;
                   9663:   int i1, j1, jk, stepsize=0;
1.194     brouard  9664:   int count=0;
                   9665: 
1.164     brouard  9666:   int *tab; 
1.136     brouard  9667:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  9668:   int backcast=0;
1.136     brouard  9669:   int mobilav=0,popforecast=0;
1.191     brouard  9670:   int hstepm=0, nhstepm=0;
1.136     brouard  9671:   int agemortsup;
                   9672:   float  sumlpop=0.;
                   9673:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   9674:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   9675: 
1.191     brouard  9676:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  9677:   double ftolpl=FTOL;
                   9678:   double **prlim;
1.217     brouard  9679:   double **bprlim;
1.136     brouard  9680:   double ***param; /* Matrix of parameters */
1.251   ! brouard  9681:   double ***paramstart; /* Matrix of starting parameter values */
        !          9682:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  9683:   double **matcov; /* Matrix of covariance */
1.203     brouard  9684:   double **hess; /* Hessian matrix */
1.136     brouard  9685:   double ***delti3; /* Scale */
                   9686:   double *delti; /* Scale */
                   9687:   double ***eij, ***vareij;
                   9688:   double **varpl; /* Variances of prevalence limits by age */
                   9689:   double *epj, vepp;
1.164     brouard  9690: 
1.136     brouard  9691:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  9692:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   9693: 
1.136     brouard  9694:   double **ximort;
1.145     brouard  9695:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  9696:   int *dcwave;
                   9697: 
1.164     brouard  9698:   char z[1]="c";
1.136     brouard  9699: 
                   9700:   /*char  *strt;*/
                   9701:   char strtend[80];
1.126     brouard  9702: 
1.164     brouard  9703: 
1.126     brouard  9704: /*   setlocale (LC_ALL, ""); */
                   9705: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   9706: /*   textdomain (PACKAGE); */
                   9707: /*   setlocale (LC_CTYPE, ""); */
                   9708: /*   setlocale (LC_MESSAGES, ""); */
                   9709: 
                   9710:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  9711:   rstart_time = time(NULL);  
                   9712:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   9713:   start_time = *localtime(&rstart_time);
1.126     brouard  9714:   curr_time=start_time;
1.157     brouard  9715:   /*tml = *localtime(&start_time.tm_sec);*/
                   9716:   /* strcpy(strstart,asctime(&tml)); */
                   9717:   strcpy(strstart,asctime(&start_time));
1.126     brouard  9718: 
                   9719: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  9720: /*  tp.tm_sec = tp.tm_sec +86400; */
                   9721: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  9722: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   9723: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   9724: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  9725: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  9726: /*   strt=asctime(&tmg); */
                   9727: /*   printf("Time(after) =%s",strstart);  */
                   9728: /*  (void) time (&time_value);
                   9729: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   9730: *  tm = *localtime(&time_value);
                   9731: *  strstart=asctime(&tm);
                   9732: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   9733: */
                   9734: 
                   9735:   nberr=0; /* Number of errors and warnings */
                   9736:   nbwarn=0;
1.184     brouard  9737: #ifdef WIN32
                   9738:   _getcwd(pathcd, size);
                   9739: #else
1.126     brouard  9740:   getcwd(pathcd, size);
1.184     brouard  9741: #endif
1.191     brouard  9742:   syscompilerinfo(0);
1.196     brouard  9743:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  9744:   if(argc <=1){
                   9745:     printf("\nEnter the parameter file name: ");
1.205     brouard  9746:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   9747:       printf("ERROR Empty parameter file name\n");
                   9748:       goto end;
                   9749:     }
1.126     brouard  9750:     i=strlen(pathr);
                   9751:     if(pathr[i-1]=='\n')
                   9752:       pathr[i-1]='\0';
1.156     brouard  9753:     i=strlen(pathr);
1.205     brouard  9754:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  9755:       pathr[i-1]='\0';
1.205     brouard  9756:     }
                   9757:     i=strlen(pathr);
                   9758:     if( i==0 ){
                   9759:       printf("ERROR Empty parameter file name\n");
                   9760:       goto end;
                   9761:     }
                   9762:     for (tok = pathr; tok != NULL; ){
1.126     brouard  9763:       printf("Pathr |%s|\n",pathr);
                   9764:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   9765:       printf("val= |%s| pathr=%s\n",val,pathr);
                   9766:       strcpy (pathtot, val);
                   9767:       if(pathr[0] == '\0') break; /* Dirty */
                   9768:     }
                   9769:   }
                   9770:   else{
                   9771:     strcpy(pathtot,argv[1]);
                   9772:   }
                   9773:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   9774:   /*cygwin_split_path(pathtot,path,optionfile);
                   9775:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   9776:   /* cutv(path,optionfile,pathtot,'\\');*/
                   9777: 
                   9778:   /* Split argv[0], imach program to get pathimach */
                   9779:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   9780:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9781:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9782:  /*   strcpy(pathimach,argv[0]); */
                   9783:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   9784:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   9785:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  9786: #ifdef WIN32
                   9787:   _chdir(path); /* Can be a relative path */
                   9788:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   9789: #else
1.126     brouard  9790:   chdir(path); /* Can be a relative path */
1.184     brouard  9791:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   9792: #endif
                   9793:   printf("Current directory %s!\n",pathcd);
1.126     brouard  9794:   strcpy(command,"mkdir ");
                   9795:   strcat(command,optionfilefiname);
                   9796:   if((outcmd=system(command)) != 0){
1.169     brouard  9797:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  9798:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   9799:     /* fclose(ficlog); */
                   9800: /*     exit(1); */
                   9801:   }
                   9802: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   9803: /*     perror("mkdir"); */
                   9804: /*   } */
                   9805: 
                   9806:   /*-------- arguments in the command line --------*/
                   9807: 
1.186     brouard  9808:   /* Main Log file */
1.126     brouard  9809:   strcat(filelog, optionfilefiname);
                   9810:   strcat(filelog,".log");    /* */
                   9811:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   9812:     printf("Problem with logfile %s\n",filelog);
                   9813:     goto end;
                   9814:   }
                   9815:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  9816:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  9817:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   9818:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   9819:  path=%s \n\
                   9820:  optionfile=%s\n\
                   9821:  optionfilext=%s\n\
1.156     brouard  9822:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  9823: 
1.197     brouard  9824:   syscompilerinfo(1);
1.167     brouard  9825: 
1.126     brouard  9826:   printf("Local time (at start):%s",strstart);
                   9827:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   9828:   fflush(ficlog);
                   9829: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  9830: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  9831: 
                   9832:   /* */
                   9833:   strcpy(fileres,"r");
                   9834:   strcat(fileres, optionfilefiname);
1.201     brouard  9835:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  9836:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  9837:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  9838: 
1.186     brouard  9839:   /* Main ---------arguments file --------*/
1.126     brouard  9840: 
                   9841:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  9842:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   9843:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  9844:     fflush(ficlog);
1.149     brouard  9845:     /* goto end; */
                   9846:     exit(70); 
1.126     brouard  9847:   }
                   9848: 
                   9849: 
                   9850: 
                   9851:   strcpy(filereso,"o");
1.201     brouard  9852:   strcat(filereso,fileresu);
1.126     brouard  9853:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   9854:     printf("Problem with Output resultfile: %s\n", filereso);
                   9855:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   9856:     fflush(ficlog);
                   9857:     goto end;
                   9858:   }
                   9859: 
                   9860:   /* Reads comments: lines beginning with '#' */
                   9861:   numlinepar=0;
1.197     brouard  9862: 
                   9863:     /* First parameter line */
                   9864:   while(fgets(line, MAXLINE, ficpar)) {
                   9865:     /* If line starts with a # it is a comment */
                   9866:     if (line[0] == '#') {
                   9867:       numlinepar++;
                   9868:       fputs(line,stdout);
                   9869:       fputs(line,ficparo);
                   9870:       fputs(line,ficlog);
                   9871:       continue;
                   9872:     }else
                   9873:       break;
                   9874:   }
                   9875:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   9876:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   9877:     if (num_filled != 5) {
                   9878:       printf("Should be 5 parameters\n");
                   9879:     }
1.126     brouard  9880:     numlinepar++;
1.197     brouard  9881:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   9882:   }
                   9883:   /* Second parameter line */
                   9884:   while(fgets(line, MAXLINE, ficpar)) {
                   9885:     /* If line starts with a # it is a comment */
                   9886:     if (line[0] == '#') {
                   9887:       numlinepar++;
                   9888:       fputs(line,stdout);
                   9889:       fputs(line,ficparo);
                   9890:       fputs(line,ficlog);
                   9891:       continue;
                   9892:     }else
                   9893:       break;
                   9894:   }
1.223     brouard  9895:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   9896:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   9897:     if (num_filled != 11) {
                   9898:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  9899:       printf("but line=%s\n",line);
1.197     brouard  9900:     }
1.223     brouard  9901:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  9902:   }
1.203     brouard  9903:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  9904:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  9905:   /* Third parameter line */
                   9906:   while(fgets(line, MAXLINE, ficpar)) {
                   9907:     /* If line starts with a # it is a comment */
                   9908:     if (line[0] == '#') {
                   9909:       numlinepar++;
                   9910:       fputs(line,stdout);
                   9911:       fputs(line,ficparo);
                   9912:       fputs(line,ficlog);
                   9913:       continue;
                   9914:     }else
                   9915:       break;
                   9916:   }
1.201     brouard  9917:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
                   9918:     if (num_filled == 0)
                   9919:             model[0]='\0';
                   9920:     else if (num_filled != 1){
1.197     brouard  9921:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   9922:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   9923:       model[0]='\0';
                   9924:       goto end;
                   9925:     }
                   9926:     else{
                   9927:       if (model[0]=='+'){
                   9928:        for(i=1; i<=strlen(model);i++)
                   9929:          modeltemp[i-1]=model[i];
1.201     brouard  9930:        strcpy(model,modeltemp); 
1.197     brouard  9931:       }
                   9932:     }
1.199     brouard  9933:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  9934:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  9935:   }
                   9936:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   9937:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   9938:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  9939:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   9940:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  9941:   fflush(ficlog);
1.190     brouard  9942:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   9943:   if(model[0]=='#'){
1.187     brouard  9944:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   9945:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   9946:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   9947:     if(mle != -1){
                   9948:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   9949:       exit(1);
                   9950:     }
                   9951:   }
1.126     brouard  9952:   while((c=getc(ficpar))=='#' && c!= EOF){
                   9953:     ungetc(c,ficpar);
                   9954:     fgets(line, MAXLINE, ficpar);
                   9955:     numlinepar++;
1.195     brouard  9956:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   9957:       z[0]=line[1];
                   9958:     }
                   9959:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  9960:     fputs(line, stdout);
                   9961:     //puts(line);
1.126     brouard  9962:     fputs(line,ficparo);
                   9963:     fputs(line,ficlog);
                   9964:   }
                   9965:   ungetc(c,ficpar);
                   9966: 
                   9967:    
1.145     brouard  9968:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.225     brouard  9969:   coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
1.233     brouard  9970:   cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.225     brouard  9971:   cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
1.136     brouard  9972:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   9973:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   9974:      v1+v2*age+v2*v3 makes cptcovn = 3
                   9975:   */
                   9976:   if (strlen(model)>1) 
1.187     brouard  9977:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  9978:   else
1.187     brouard  9979:     ncovmodel=2; /* Constant and age */
1.133     brouard  9980:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   9981:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  9982:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   9983:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   9984:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   9985:     fflush(stdout);
                   9986:     fclose (ficlog);
                   9987:     goto end;
                   9988:   }
1.126     brouard  9989:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   9990:   delti=delti3[1][1];
                   9991:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   9992:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  9993: /* We could also provide initial parameters values giving by simple logistic regression 
                   9994:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   9995:       /* for(i=1;i<nlstate;i++){ */
                   9996:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   9997:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   9998:       /* } */
1.126     brouard  9999:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  10000:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   10001:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10002:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   10003:     fclose (ficparo);
                   10004:     fclose (ficlog);
                   10005:     goto end;
                   10006:     exit(0);
1.248     brouard  10007:   } else if(mle==-2) { /* Guessing from means */
                   10008:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
                   10009:     printf(" You chose mle=-2, look at file %s for a template of covariance matrix \n",filereso);
                   10010:     fprintf(ficlog," You chose mle=-2, look at file %s for a template of covariance matrix \n",filereso);
                   10011:    
1.220     brouard  10012:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  10013:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  10014:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   10015:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10016:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10017:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10018:     hess=matrix(1,npar,1,npar);
1.220     brouard  10019:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  10020:     /* Read guessed parameters */
1.126     brouard  10021:     /* Reads comments: lines beginning with '#' */
                   10022:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10023:       ungetc(c,ficpar);
                   10024:       fgets(line, MAXLINE, ficpar);
                   10025:       numlinepar++;
1.141     brouard  10026:       fputs(line,stdout);
1.126     brouard  10027:       fputs(line,ficparo);
                   10028:       fputs(line,ficlog);
                   10029:     }
                   10030:     ungetc(c,ficpar);
                   10031:     
                   10032:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251   ! brouard  10033:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  10034:     for(i=1; i <=nlstate; i++){
1.234     brouard  10035:       j=0;
1.126     brouard  10036:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  10037:        if(jj==i) continue;
                   10038:        j++;
                   10039:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10040:        if ((i1 != i) || (j1 != jj)){
                   10041:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  10042: It might be a problem of design; if ncovcol and the model are correct\n \
                   10043: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  10044:          exit(1);
                   10045:        }
                   10046:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10047:        if(mle==1)
                   10048:          printf("%1d%1d",i,jj);
                   10049:        fprintf(ficlog,"%1d%1d",i,jj);
                   10050:        for(k=1; k<=ncovmodel;k++){
                   10051:          fscanf(ficpar," %lf",&param[i][j][k]);
                   10052:          if(mle==1){
                   10053:            printf(" %lf",param[i][j][k]);
                   10054:            fprintf(ficlog," %lf",param[i][j][k]);
                   10055:          }
                   10056:          else
                   10057:            fprintf(ficlog," %lf",param[i][j][k]);
                   10058:          fprintf(ficparo," %lf",param[i][j][k]);
                   10059:        }
                   10060:        fscanf(ficpar,"\n");
                   10061:        numlinepar++;
                   10062:        if(mle==1)
                   10063:          printf("\n");
                   10064:        fprintf(ficlog,"\n");
                   10065:        fprintf(ficparo,"\n");
1.126     brouard  10066:       }
                   10067:     }  
                   10068:     fflush(ficlog);
1.234     brouard  10069:     
1.251   ! brouard  10070:     /* Reads parameters values */
1.126     brouard  10071:     p=param[1][1];
1.251   ! brouard  10072:     pstart=paramstart[1][1];
1.126     brouard  10073:     
                   10074:     /* Reads comments: lines beginning with '#' */
                   10075:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10076:       ungetc(c,ficpar);
                   10077:       fgets(line, MAXLINE, ficpar);
                   10078:       numlinepar++;
1.141     brouard  10079:       fputs(line,stdout);
1.126     brouard  10080:       fputs(line,ficparo);
                   10081:       fputs(line,ficlog);
                   10082:     }
                   10083:     ungetc(c,ficpar);
                   10084: 
                   10085:     for(i=1; i <=nlstate; i++){
                   10086:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  10087:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10088:        if ( (i1-i) * (j1-j) != 0){
                   10089:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   10090:          exit(1);
                   10091:        }
                   10092:        printf("%1d%1d",i,j);
                   10093:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10094:        fprintf(ficlog,"%1d%1d",i1,j1);
                   10095:        for(k=1; k<=ncovmodel;k++){
                   10096:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   10097:          printf(" %le",delti3[i][j][k]);
                   10098:          fprintf(ficparo," %le",delti3[i][j][k]);
                   10099:          fprintf(ficlog," %le",delti3[i][j][k]);
                   10100:        }
                   10101:        fscanf(ficpar,"\n");
                   10102:        numlinepar++;
                   10103:        printf("\n");
                   10104:        fprintf(ficparo,"\n");
                   10105:        fprintf(ficlog,"\n");
1.126     brouard  10106:       }
                   10107:     }
                   10108:     fflush(ficlog);
1.234     brouard  10109:     
1.145     brouard  10110:     /* Reads covariance matrix */
1.126     brouard  10111:     delti=delti3[1][1];
1.220     brouard  10112:                
                   10113:                
1.126     brouard  10114:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  10115:                
1.126     brouard  10116:     /* Reads comments: lines beginning with '#' */
                   10117:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10118:       ungetc(c,ficpar);
                   10119:       fgets(line, MAXLINE, ficpar);
                   10120:       numlinepar++;
1.141     brouard  10121:       fputs(line,stdout);
1.126     brouard  10122:       fputs(line,ficparo);
                   10123:       fputs(line,ficlog);
                   10124:     }
                   10125:     ungetc(c,ficpar);
1.220     brouard  10126:                
1.126     brouard  10127:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10128:     hess=matrix(1,npar,1,npar);
1.131     brouard  10129:     for(i=1; i <=npar; i++)
                   10130:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  10131:                
1.194     brouard  10132:     /* Scans npar lines */
1.126     brouard  10133:     for(i=1; i <=npar; i++){
1.226     brouard  10134:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  10135:       if(count != 3){
1.226     brouard  10136:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10137: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10138: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10139:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10140: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10141: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10142:        exit(1);
1.220     brouard  10143:       }else{
1.226     brouard  10144:        if(mle==1)
                   10145:          printf("%1d%1d%d",i1,j1,jk);
                   10146:       }
                   10147:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   10148:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  10149:       for(j=1; j <=i; j++){
1.226     brouard  10150:        fscanf(ficpar," %le",&matcov[i][j]);
                   10151:        if(mle==1){
                   10152:          printf(" %.5le",matcov[i][j]);
                   10153:        }
                   10154:        fprintf(ficlog," %.5le",matcov[i][j]);
                   10155:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  10156:       }
                   10157:       fscanf(ficpar,"\n");
                   10158:       numlinepar++;
                   10159:       if(mle==1)
1.220     brouard  10160:                                printf("\n");
1.126     brouard  10161:       fprintf(ficlog,"\n");
                   10162:       fprintf(ficparo,"\n");
                   10163:     }
1.194     brouard  10164:     /* End of read covariance matrix npar lines */
1.126     brouard  10165:     for(i=1; i <=npar; i++)
                   10166:       for(j=i+1;j<=npar;j++)
1.226     brouard  10167:        matcov[i][j]=matcov[j][i];
1.126     brouard  10168:     
                   10169:     if(mle==1)
                   10170:       printf("\n");
                   10171:     fprintf(ficlog,"\n");
                   10172:     
                   10173:     fflush(ficlog);
                   10174:     
                   10175:     /*-------- Rewriting parameter file ----------*/
                   10176:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   10177:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   10178:     strcat(rfileres,".");    /* */
                   10179:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10180:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  10181:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10182:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  10183:     }
                   10184:     fprintf(ficres,"#%s\n",version);
                   10185:   }    /* End of mle != -3 */
1.218     brouard  10186:   
1.186     brouard  10187:   /*  Main data
                   10188:    */
1.126     brouard  10189:   n= lastobs;
                   10190:   num=lvector(1,n);
                   10191:   moisnais=vector(1,n);
                   10192:   annais=vector(1,n);
                   10193:   moisdc=vector(1,n);
                   10194:   andc=vector(1,n);
1.220     brouard  10195:   weight=vector(1,n);
1.126     brouard  10196:   agedc=vector(1,n);
                   10197:   cod=ivector(1,n);
1.220     brouard  10198:   for(i=1;i<=n;i++){
1.234     brouard  10199:     num[i]=0;
                   10200:     moisnais[i]=0;
                   10201:     annais[i]=0;
                   10202:     moisdc[i]=0;
                   10203:     andc[i]=0;
                   10204:     agedc[i]=0;
                   10205:     cod[i]=0;
                   10206:     weight[i]=1.0; /* Equal weights, 1 by default */
                   10207:   }
1.126     brouard  10208:   mint=matrix(1,maxwav,1,n);
                   10209:   anint=matrix(1,maxwav,1,n);
1.131     brouard  10210:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  10211:   tab=ivector(1,NCOVMAX);
1.144     brouard  10212:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  10213:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  10214: 
1.136     brouard  10215:   /* Reads data from file datafile */
                   10216:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   10217:     goto end;
                   10218: 
                   10219:   /* Calculation of the number of parameters from char model */
1.234     brouard  10220:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  10221:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   10222:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   10223:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   10224:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  10225:   */
                   10226:   
                   10227:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   10228:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   10229:   TvarsD=ivector(1,NCOVMAX); /*  */
                   10230:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   10231:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  10232:   TvarF=ivector(1,NCOVMAX); /*  */
                   10233:   TvarFind=ivector(1,NCOVMAX); /*  */
                   10234:   TvarV=ivector(1,NCOVMAX); /*  */
                   10235:   TvarVind=ivector(1,NCOVMAX); /*  */
                   10236:   TvarA=ivector(1,NCOVMAX); /*  */
                   10237:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  10238:   TvarFD=ivector(1,NCOVMAX); /*  */
                   10239:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   10240:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   10241:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   10242:   TvarVD=ivector(1,NCOVMAX); /*  */
                   10243:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   10244:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   10245:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   10246: 
1.230     brouard  10247:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  10248:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  10249:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   10250:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   10251:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  10252:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   10253:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   10254:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   10255:   */
                   10256:   /* For model-covariate k tells which data-covariate to use but
                   10257:     because this model-covariate is a construction we invent a new column
                   10258:     ncovcol + k1
                   10259:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   10260:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  10261:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   10262:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  10263:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   10264:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  10265:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  10266:   */
1.145     brouard  10267:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   10268:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  10269:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   10270:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  10271:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  10272:                         4 covariates (3 plus signs)
                   10273:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   10274:                      */  
1.230     brouard  10275:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  10276:                                * individual dummy, fixed or varying:
                   10277:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   10278:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  10279:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   10280:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   10281:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   10282:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   10283:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  10284:                                * individual quantitative, fixed or varying:
                   10285:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   10286:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   10287:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  10288: /* Main decodemodel */
                   10289: 
1.187     brouard  10290: 
1.223     brouard  10291:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  10292:     goto end;
                   10293: 
1.137     brouard  10294:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   10295:     nbwarn++;
                   10296:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10297:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10298:   }
1.136     brouard  10299:     /*  if(mle==1){*/
1.137     brouard  10300:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   10301:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  10302:   }
                   10303: 
                   10304:     /*-calculation of age at interview from date of interview and age at death -*/
                   10305:   agev=matrix(1,maxwav,1,imx);
                   10306: 
                   10307:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   10308:     goto end;
                   10309: 
1.126     brouard  10310: 
1.136     brouard  10311:   agegomp=(int)agemin;
                   10312:   free_vector(moisnais,1,n);
                   10313:   free_vector(annais,1,n);
1.126     brouard  10314:   /* free_matrix(mint,1,maxwav,1,n);
                   10315:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  10316:   /* free_vector(moisdc,1,n); */
                   10317:   /* free_vector(andc,1,n); */
1.145     brouard  10318:   /* */
                   10319:   
1.126     brouard  10320:   wav=ivector(1,imx);
1.214     brouard  10321:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10322:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10323:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10324:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   10325:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   10326:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  10327:    
                   10328:   /* Concatenates waves */
1.214     brouard  10329:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   10330:      Death is a valid wave (if date is known).
                   10331:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   10332:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   10333:      and mw[mi+1][i]. dh depends on stepm.
                   10334:   */
                   10335: 
1.126     brouard  10336:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  10337:   /* Concatenates waves */
1.145     brouard  10338:  
1.215     brouard  10339:   free_vector(moisdc,1,n);
                   10340:   free_vector(andc,1,n);
                   10341: 
1.126     brouard  10342:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   10343:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   10344:   ncodemax[1]=1;
1.145     brouard  10345:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  10346:   cptcoveff=0;
1.220     brouard  10347:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   10348:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  10349:   }
                   10350:   
                   10351:   ncovcombmax=pow(2,cptcoveff);
                   10352:   invalidvarcomb=ivector(1, ncovcombmax); 
                   10353:   for(i=1;i<ncovcombmax;i++)
                   10354:     invalidvarcomb[i]=0;
                   10355:   
1.211     brouard  10356:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  10357:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  10358:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  10359:   
1.200     brouard  10360:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  10361:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  10362:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  10363:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   10364:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   10365:    * (currently 0 or 1) in the data.
                   10366:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   10367:    * corresponding modality (h,j).
                   10368:    */
                   10369: 
1.145     brouard  10370:   h=0;
                   10371:   /*if (cptcovn > 0) */
1.126     brouard  10372:   m=pow(2,cptcoveff);
                   10373:  
1.144     brouard  10374:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  10375:           * For k=4 covariates, h goes from 1 to m=2**k
                   10376:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   10377:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  10378:           *     h\k   1     2     3     4
1.143     brouard  10379:           *______________________________  
                   10380:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   10381:           *     2     2     1     1     1
                   10382:           *     3 i=2 1     2     1     1
                   10383:           *     4     2     2     1     1
                   10384:           *     5 i=3 1 i=2 1     2     1
                   10385:           *     6     2     1     2     1
                   10386:           *     7 i=4 1     2     2     1
                   10387:           *     8     2     2     2     1
1.197     brouard  10388:           *     9 i=5 1 i=3 1 i=2 1     2
                   10389:           *    10     2     1     1     2
                   10390:           *    11 i=6 1     2     1     2
                   10391:           *    12     2     2     1     2
                   10392:           *    13 i=7 1 i=4 1     2     2    
                   10393:           *    14     2     1     2     2
                   10394:           *    15 i=8 1     2     2     2
                   10395:           *    16     2     2     2     2
1.143     brouard  10396:           */
1.212     brouard  10397:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  10398:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   10399:      * and the value of each covariate?
                   10400:      * V1=1, V2=1, V3=2, V4=1 ?
                   10401:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   10402:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   10403:      * In order to get the real value in the data, we use nbcode
                   10404:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   10405:      * We are keeping this crazy system in order to be able (in the future?) 
                   10406:      * to have more than 2 values (0 or 1) for a covariate.
                   10407:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   10408:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   10409:      *              bbbbbbbb
                   10410:      *              76543210     
                   10411:      *   h-1        00000101 (6-1=5)
1.219     brouard  10412:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  10413:      *           &
                   10414:      *     1        00000001 (1)
1.219     brouard  10415:      *              00000000        = 1 & ((h-1) >> (k-1))
                   10416:      *          +1= 00000001 =1 
1.211     brouard  10417:      *
                   10418:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   10419:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   10420:      *    >>k'            11
                   10421:      *          &   00000001
                   10422:      *            = 00000001
                   10423:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   10424:      * Reverse h=6 and m=16?
                   10425:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   10426:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   10427:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   10428:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   10429:      * V3=decodtabm(14,3,2**4)=2
                   10430:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   10431:      *(h-1) >> (j-1)    0011 =13 >> 2
                   10432:      *          &1 000000001
                   10433:      *           = 000000001
                   10434:      *         +1= 000000010 =2
                   10435:      *                  2211
                   10436:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   10437:      *                  V3=2
1.220     brouard  10438:                 * codtabm and decodtabm are identical
1.211     brouard  10439:      */
                   10440: 
1.145     brouard  10441: 
                   10442:  free_ivector(Ndum,-1,NCOVMAX);
                   10443: 
                   10444: 
1.126     brouard  10445:     
1.186     brouard  10446:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  10447:   strcpy(optionfilegnuplot,optionfilefiname);
                   10448:   if(mle==-3)
1.201     brouard  10449:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  10450:   strcat(optionfilegnuplot,".gp");
                   10451: 
                   10452:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   10453:     printf("Problem with file %s",optionfilegnuplot);
                   10454:   }
                   10455:   else{
1.204     brouard  10456:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  10457:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  10458:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   10459:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  10460:   }
                   10461:   /*  fclose(ficgp);*/
1.186     brouard  10462: 
                   10463: 
                   10464:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  10465: 
                   10466:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   10467:   if(mle==-3)
1.201     brouard  10468:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  10469:   strcat(optionfilehtm,".htm");
                   10470:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  10471:     printf("Problem with %s \n",optionfilehtm);
                   10472:     exit(0);
1.126     brouard  10473:   }
                   10474: 
                   10475:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   10476:   strcat(optionfilehtmcov,"-cov.htm");
                   10477:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   10478:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   10479:   }
                   10480:   else{
                   10481:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   10482: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10483: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  10484:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   10485:   }
                   10486: 
1.213     brouard  10487:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  10488: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   10489: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  10490: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10491: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  10492: \n\
                   10493: <hr  size=\"2\" color=\"#EC5E5E\">\
                   10494:  <ul><li><h4>Parameter files</h4>\n\
                   10495:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   10496:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   10497:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   10498:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   10499:  - Date and time at start: %s</ul>\n",\
                   10500:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   10501:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   10502:          fileres,fileres,\
                   10503:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   10504:   fflush(fichtm);
                   10505: 
                   10506:   strcpy(pathr,path);
                   10507:   strcat(pathr,optionfilefiname);
1.184     brouard  10508: #ifdef WIN32
                   10509:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   10510: #else
1.126     brouard  10511:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  10512: #endif
                   10513:          
1.126     brouard  10514:   
1.220     brouard  10515:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   10516:                 and for any valid combination of covariates
1.126     brouard  10517:      and prints on file fileres'p'. */
1.251   ! brouard  10518:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  10519:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  10520: 
                   10521:   fprintf(fichtm,"\n");
                   10522:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   10523: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   10524: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   10525:          imx,agemin,agemax,jmin,jmax,jmean);
                   10526:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.220     brouard  10527:        oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10528:        newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10529:        savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10530:        oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  10531: 
1.126     brouard  10532:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   10533:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   10534:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   10535: 
                   10536:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  10537:   /* For mortality only */
1.126     brouard  10538:   if (mle==-3){
1.136     brouard  10539:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  10540:     for(i=1;i<=NDIM;i++)
                   10541:       for(j=1;j<=NDIM;j++)
                   10542:        ximort[i][j]=0.;
1.186     brouard  10543:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  10544:     cens=ivector(1,n);
                   10545:     ageexmed=vector(1,n);
                   10546:     agecens=vector(1,n);
                   10547:     dcwave=ivector(1,n);
1.223     brouard  10548:                
1.126     brouard  10549:     for (i=1; i<=imx; i++){
                   10550:       dcwave[i]=-1;
                   10551:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  10552:        if (s[m][i]>nlstate) {
                   10553:          dcwave[i]=m;
                   10554:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   10555:          break;
                   10556:        }
1.126     brouard  10557:     }
1.226     brouard  10558:     
1.126     brouard  10559:     for (i=1; i<=imx; i++) {
                   10560:       if (wav[i]>0){
1.226     brouard  10561:        ageexmed[i]=agev[mw[1][i]][i];
                   10562:        j=wav[i];
                   10563:        agecens[i]=1.; 
                   10564:        
                   10565:        if (ageexmed[i]> 1 && wav[i] > 0){
                   10566:          agecens[i]=agev[mw[j][i]][i];
                   10567:          cens[i]= 1;
                   10568:        }else if (ageexmed[i]< 1) 
                   10569:          cens[i]= -1;
                   10570:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   10571:          cens[i]=0 ;
1.126     brouard  10572:       }
                   10573:       else cens[i]=-1;
                   10574:     }
                   10575:     
                   10576:     for (i=1;i<=NDIM;i++) {
                   10577:       for (j=1;j<=NDIM;j++)
1.226     brouard  10578:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  10579:     }
                   10580:     
1.145     brouard  10581:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  10582:     /*printf("%lf %lf", p[1], p[2]);*/
                   10583:     
                   10584:     
1.136     brouard  10585: #ifdef GSL
                   10586:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  10587: #else
1.126     brouard  10588:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  10589: #endif
1.201     brouard  10590:     strcpy(filerespow,"POW-MORT_"); 
                   10591:     strcat(filerespow,fileresu);
1.126     brouard  10592:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   10593:       printf("Problem with resultfile: %s\n", filerespow);
                   10594:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   10595:     }
1.136     brouard  10596: #ifdef GSL
                   10597:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  10598: #else
1.126     brouard  10599:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  10600: #endif
1.126     brouard  10601:     /*  for (i=1;i<=nlstate;i++)
                   10602:        for(j=1;j<=nlstate+ndeath;j++)
                   10603:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   10604:     */
                   10605:     fprintf(ficrespow,"\n");
1.136     brouard  10606: #ifdef GSL
                   10607:     /* gsl starts here */ 
                   10608:     T = gsl_multimin_fminimizer_nmsimplex;
                   10609:     gsl_multimin_fminimizer *sfm = NULL;
                   10610:     gsl_vector *ss, *x;
                   10611:     gsl_multimin_function minex_func;
                   10612: 
                   10613:     /* Initial vertex size vector */
                   10614:     ss = gsl_vector_alloc (NDIM);
                   10615:     
                   10616:     if (ss == NULL){
                   10617:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   10618:     }
                   10619:     /* Set all step sizes to 1 */
                   10620:     gsl_vector_set_all (ss, 0.001);
                   10621: 
                   10622:     /* Starting point */
1.126     brouard  10623:     
1.136     brouard  10624:     x = gsl_vector_alloc (NDIM);
                   10625:     
                   10626:     if (x == NULL){
                   10627:       gsl_vector_free(ss);
                   10628:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   10629:     }
                   10630:   
                   10631:     /* Initialize method and iterate */
                   10632:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  10633:     /*     gsl_vector_set(x, 0, 0.0268); */
                   10634:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  10635:     gsl_vector_set(x, 0, p[1]);
                   10636:     gsl_vector_set(x, 1, p[2]);
                   10637: 
                   10638:     minex_func.f = &gompertz_f;
                   10639:     minex_func.n = NDIM;
                   10640:     minex_func.params = (void *)&p; /* ??? */
                   10641:     
                   10642:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   10643:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   10644:     
                   10645:     printf("Iterations beginning .....\n\n");
                   10646:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   10647: 
                   10648:     iteri=0;
                   10649:     while (rval == GSL_CONTINUE){
                   10650:       iteri++;
                   10651:       status = gsl_multimin_fminimizer_iterate(sfm);
                   10652:       
                   10653:       if (status) printf("error: %s\n", gsl_strerror (status));
                   10654:       fflush(0);
                   10655:       
                   10656:       if (status) 
                   10657:         break;
                   10658:       
                   10659:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   10660:       ssval = gsl_multimin_fminimizer_size (sfm);
                   10661:       
                   10662:       if (rval == GSL_SUCCESS)
                   10663:         printf ("converged to a local maximum at\n");
                   10664:       
                   10665:       printf("%5d ", iteri);
                   10666:       for (it = 0; it < NDIM; it++){
                   10667:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   10668:       }
                   10669:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   10670:     }
                   10671:     
                   10672:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   10673:     
                   10674:     gsl_vector_free(x); /* initial values */
                   10675:     gsl_vector_free(ss); /* inital step size */
                   10676:     for (it=0; it<NDIM; it++){
                   10677:       p[it+1]=gsl_vector_get(sfm->x,it);
                   10678:       fprintf(ficrespow," %.12lf", p[it]);
                   10679:     }
                   10680:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   10681: #endif
                   10682: #ifdef POWELL
                   10683:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   10684: #endif  
1.126     brouard  10685:     fclose(ficrespow);
                   10686:     
1.203     brouard  10687:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  10688: 
                   10689:     for(i=1; i <=NDIM; i++)
                   10690:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  10691:                                matcov[i][j]=matcov[j][i];
1.126     brouard  10692:     
                   10693:     printf("\nCovariance matrix\n ");
1.203     brouard  10694:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  10695:     for(i=1; i <=NDIM; i++) {
                   10696:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  10697:                                printf("%f ",matcov[i][j]);
                   10698:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  10699:       }
1.203     brouard  10700:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  10701:     }
                   10702:     
                   10703:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  10704:     for (i=1;i<=NDIM;i++) {
1.126     brouard  10705:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  10706:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   10707:     }
1.126     brouard  10708:     lsurv=vector(1,AGESUP);
                   10709:     lpop=vector(1,AGESUP);
                   10710:     tpop=vector(1,AGESUP);
                   10711:     lsurv[agegomp]=100000;
                   10712:     
                   10713:     for (k=agegomp;k<=AGESUP;k++) {
                   10714:       agemortsup=k;
                   10715:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   10716:     }
                   10717:     
                   10718:     for (k=agegomp;k<agemortsup;k++)
                   10719:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   10720:     
                   10721:     for (k=agegomp;k<agemortsup;k++){
                   10722:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   10723:       sumlpop=sumlpop+lpop[k];
                   10724:     }
                   10725:     
                   10726:     tpop[agegomp]=sumlpop;
                   10727:     for (k=agegomp;k<(agemortsup-3);k++){
                   10728:       /*  tpop[k+1]=2;*/
                   10729:       tpop[k+1]=tpop[k]-lpop[k];
                   10730:     }
                   10731:     
                   10732:     
                   10733:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   10734:     for (k=agegomp;k<(agemortsup-2);k++) 
                   10735:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   10736:     
                   10737:     
                   10738:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  10739:                ageminpar=50;
                   10740:                agemaxpar=100;
1.194     brouard  10741:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   10742:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10743: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10744: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   10745:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10746: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10747: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10748:     }else{
                   10749:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   10750:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  10751:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  10752:                }
1.201     brouard  10753:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  10754:                     stepm, weightopt,\
                   10755:                     model,imx,p,matcov,agemortsup);
                   10756:     
                   10757:     free_vector(lsurv,1,AGESUP);
                   10758:     free_vector(lpop,1,AGESUP);
                   10759:     free_vector(tpop,1,AGESUP);
1.220     brouard  10760:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  10761:     free_ivector(cens,1,n);
                   10762:     free_vector(agecens,1,n);
                   10763:     free_ivector(dcwave,1,n);
1.220     brouard  10764: #ifdef GSL
1.136     brouard  10765: #endif
1.186     brouard  10766:   } /* Endof if mle==-3 mortality only */
1.205     brouard  10767:   /* Standard  */
                   10768:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   10769:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10770:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  10771:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  10772:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10773:     for (k=1; k<=npar;k++)
                   10774:       printf(" %d %8.5f",k,p[k]);
                   10775:     printf("\n");
1.205     brouard  10776:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   10777:       /* mlikeli uses func not funcone */
1.247     brouard  10778:       /* for(i=1;i<nlstate;i++){ */
                   10779:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10780:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10781:       /* } */
1.205     brouard  10782:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   10783:     }
                   10784:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   10785:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10786:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   10787:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10788:     }
                   10789:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  10790:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10791:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10792:     for (k=1; k<=npar;k++)
                   10793:       printf(" %d %8.5f",k,p[k]);
                   10794:     printf("\n");
                   10795:     
                   10796:     /*--------- results files --------------*/
1.224     brouard  10797:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  10798:     
                   10799:     
                   10800:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10801:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10802:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10803:     for(i=1,jk=1; i <=nlstate; i++){
                   10804:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  10805:        if (k != i) {
                   10806:          printf("%d%d ",i,k);
                   10807:          fprintf(ficlog,"%d%d ",i,k);
                   10808:          fprintf(ficres,"%1d%1d ",i,k);
                   10809:          for(j=1; j <=ncovmodel; j++){
                   10810:            printf("%12.7f ",p[jk]);
                   10811:            fprintf(ficlog,"%12.7f ",p[jk]);
                   10812:            fprintf(ficres,"%12.7f ",p[jk]);
                   10813:            jk++; 
                   10814:          }
                   10815:          printf("\n");
                   10816:          fprintf(ficlog,"\n");
                   10817:          fprintf(ficres,"\n");
                   10818:        }
1.126     brouard  10819:       }
                   10820:     }
1.203     brouard  10821:     if(mle != 0){
                   10822:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  10823:       ftolhess=ftol; /* Usually correct */
1.203     brouard  10824:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   10825:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10826:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10827:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  10828:        for(k=1; k <=(nlstate+ndeath); k++){
                   10829:          if (k != i) {
                   10830:            printf("%d%d ",i,k);
                   10831:            fprintf(ficlog,"%d%d ",i,k);
                   10832:            for(j=1; j <=ncovmodel; j++){
                   10833:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10834:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10835:              jk++; 
                   10836:            }
                   10837:            printf("\n");
                   10838:            fprintf(ficlog,"\n");
                   10839:          }
                   10840:        }
1.193     brouard  10841:       }
1.203     brouard  10842:     } /* end of hesscov and Wald tests */
1.225     brouard  10843:     
1.203     brouard  10844:     /*  */
1.126     brouard  10845:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   10846:     printf("# Scales (for hessian or gradient estimation)\n");
                   10847:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   10848:     for(i=1,jk=1; i <=nlstate; i++){
                   10849:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  10850:        if (j!=i) {
                   10851:          fprintf(ficres,"%1d%1d",i,j);
                   10852:          printf("%1d%1d",i,j);
                   10853:          fprintf(ficlog,"%1d%1d",i,j);
                   10854:          for(k=1; k<=ncovmodel;k++){
                   10855:            printf(" %.5e",delti[jk]);
                   10856:            fprintf(ficlog," %.5e",delti[jk]);
                   10857:            fprintf(ficres," %.5e",delti[jk]);
                   10858:            jk++;
                   10859:          }
                   10860:          printf("\n");
                   10861:          fprintf(ficlog,"\n");
                   10862:          fprintf(ficres,"\n");
                   10863:        }
1.126     brouard  10864:       }
                   10865:     }
                   10866:     
                   10867:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  10868:     if(mle >= 1) /* To big for the screen */
1.126     brouard  10869:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   10870:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   10871:     /* # 121 Var(a12)\n\ */
                   10872:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   10873:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   10874:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   10875:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   10876:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   10877:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   10878:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   10879:     
                   10880:     
                   10881:     /* Just to have a covariance matrix which will be more understandable
                   10882:        even is we still don't want to manage dictionary of variables
                   10883:     */
                   10884:     for(itimes=1;itimes<=2;itimes++){
                   10885:       jj=0;
                   10886:       for(i=1; i <=nlstate; i++){
1.225     brouard  10887:        for(j=1; j <=nlstate+ndeath; j++){
                   10888:          if(j==i) continue;
                   10889:          for(k=1; k<=ncovmodel;k++){
                   10890:            jj++;
                   10891:            ca[0]= k+'a'-1;ca[1]='\0';
                   10892:            if(itimes==1){
                   10893:              if(mle>=1)
                   10894:                printf("#%1d%1d%d",i,j,k);
                   10895:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   10896:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   10897:            }else{
                   10898:              if(mle>=1)
                   10899:                printf("%1d%1d%d",i,j,k);
                   10900:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   10901:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   10902:            }
                   10903:            ll=0;
                   10904:            for(li=1;li <=nlstate; li++){
                   10905:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   10906:                if(lj==li) continue;
                   10907:                for(lk=1;lk<=ncovmodel;lk++){
                   10908:                  ll++;
                   10909:                  if(ll<=jj){
                   10910:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   10911:                    if(ll<jj){
                   10912:                      if(itimes==1){
                   10913:                        if(mle>=1)
                   10914:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10915:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10916:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10917:                      }else{
                   10918:                        if(mle>=1)
                   10919:                          printf(" %.5e",matcov[jj][ll]); 
                   10920:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   10921:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   10922:                      }
                   10923:                    }else{
                   10924:                      if(itimes==1){
                   10925:                        if(mle>=1)
                   10926:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   10927:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   10928:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   10929:                      }else{
                   10930:                        if(mle>=1)
                   10931:                          printf(" %.7e",matcov[jj][ll]); 
                   10932:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   10933:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   10934:                      }
                   10935:                    }
                   10936:                  }
                   10937:                } /* end lk */
                   10938:              } /* end lj */
                   10939:            } /* end li */
                   10940:            if(mle>=1)
                   10941:              printf("\n");
                   10942:            fprintf(ficlog,"\n");
                   10943:            fprintf(ficres,"\n");
                   10944:            numlinepar++;
                   10945:          } /* end k*/
                   10946:        } /*end j */
1.126     brouard  10947:       } /* end i */
                   10948:     } /* end itimes */
                   10949:     
                   10950:     fflush(ficlog);
                   10951:     fflush(ficres);
1.225     brouard  10952:     while(fgets(line, MAXLINE, ficpar)) {
                   10953:       /* If line starts with a # it is a comment */
                   10954:       if (line[0] == '#') {
                   10955:        numlinepar++;
                   10956:        fputs(line,stdout);
                   10957:        fputs(line,ficparo);
                   10958:        fputs(line,ficlog);
                   10959:        continue;
                   10960:       }else
                   10961:        break;
                   10962:     }
                   10963:     
1.209     brouard  10964:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   10965:     /*   ungetc(c,ficpar); */
                   10966:     /*   fgets(line, MAXLINE, ficpar); */
                   10967:     /*   fputs(line,stdout); */
                   10968:     /*   fputs(line,ficparo); */
                   10969:     /* } */
                   10970:     /* ungetc(c,ficpar); */
1.126     brouard  10971:     
                   10972:     estepm=0;
1.209     brouard  10973:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  10974:       
                   10975:       if (num_filled != 6) {
                   10976:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   10977:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   10978:        goto end;
                   10979:       }
                   10980:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   10981:     }
                   10982:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   10983:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   10984:     
1.209     brouard  10985:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  10986:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   10987:     if (fage <= 2) {
                   10988:       bage = ageminpar;
                   10989:       fage = agemaxpar;
                   10990:     }
                   10991:     
                   10992:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  10993:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   10994:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  10995:                
1.186     brouard  10996:     /* Other stuffs, more or less useful */    
1.126     brouard  10997:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10998:       ungetc(c,ficpar);
                   10999:       fgets(line, MAXLINE, ficpar);
1.141     brouard  11000:       fputs(line,stdout);
1.126     brouard  11001:       fputs(line,ficparo);
                   11002:     }
                   11003:     ungetc(c,ficpar);
                   11004:     
                   11005:     fscanf(ficpar,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav);
                   11006:     fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11007:     fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11008:     printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11009:     fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11010:     
                   11011:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11012:       ungetc(c,ficpar);
                   11013:       fgets(line, MAXLINE, ficpar);
1.141     brouard  11014:       fputs(line,stdout);
1.126     brouard  11015:       fputs(line,ficparo);
                   11016:     }
                   11017:     ungetc(c,ficpar);
                   11018:     
                   11019:     
                   11020:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   11021:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   11022:     
                   11023:     fscanf(ficpar,"pop_based=%d\n",&popbased);
1.193     brouard  11024:     fprintf(ficlog,"pop_based=%d\n",popbased);
1.126     brouard  11025:     fprintf(ficparo,"pop_based=%d\n",popbased);   
                   11026:     fprintf(ficres,"pop_based=%d\n",popbased);   
                   11027:     
                   11028:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11029:       ungetc(c,ficpar);
                   11030:       fgets(line, MAXLINE, ficpar);
1.141     brouard  11031:       fputs(line,stdout);
1.238     brouard  11032:       fputs(line,ficres);
1.126     brouard  11033:       fputs(line,ficparo);
                   11034:     }
                   11035:     ungetc(c,ficpar);
                   11036:     
                   11037:     fscanf(ficpar,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj);
                   11038:     fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11039:     printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11040:     fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11041:     fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11042:     /* day and month of proj2 are not used but only year anproj2.*/
                   11043:     
1.217     brouard  11044:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11045:       ungetc(c,ficpar);
                   11046:       fgets(line, MAXLINE, ficpar);
                   11047:       fputs(line,stdout);
                   11048:       fputs(line,ficparo);
1.238     brouard  11049:       fputs(line,ficres);
1.217     brouard  11050:     }
                   11051:     ungetc(c,ficpar);
                   11052:     
                   11053:     fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);
1.223     brouard  11054:     fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11055:     fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11056:     fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
1.217     brouard  11057:     /* day and month of proj2 are not used but only year anproj2.*/
1.126     brouard  11058:     
1.230     brouard  11059:     /* Results */
1.235     brouard  11060:     nresult=0;
1.230     brouard  11061:     while(fgets(line, MAXLINE, ficpar)) {
                   11062:       /* If line starts with a # it is a comment */
                   11063:       if (line[0] == '#') {
                   11064:        numlinepar++;
                   11065:        fputs(line,stdout);
                   11066:        fputs(line,ficparo);
                   11067:        fputs(line,ficlog);
1.238     brouard  11068:        fputs(line,ficres);
1.230     brouard  11069:        continue;
                   11070:       }else
                   11071:        break;
                   11072:     }
1.240     brouard  11073:     if (!feof(ficpar))
1.230     brouard  11074:     while((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
1.240     brouard  11075:       if (num_filled == 0){
1.230     brouard  11076:        resultline[0]='\0';
1.240     brouard  11077:       break;
                   11078:       } else if (num_filled != 1){
1.230     brouard  11079:        printf("ERROR %d: result line should be at minimum 'result=' %s\n",num_filled, line);
                   11080:       }
1.235     brouard  11081:       nresult++; /* Sum of resultlines */
                   11082:       printf("Result %d: result=%s\n",nresult, resultline);
                   11083:       if(nresult > MAXRESULTLINES){
                   11084:        printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11085:        fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11086:        goto end;
                   11087:       }
                   11088:       decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
1.238     brouard  11089:       fprintf(ficparo,"result: %s\n",resultline);
                   11090:       fprintf(ficres,"result: %s\n",resultline);
                   11091:       fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  11092:       while(fgets(line, MAXLINE, ficpar)) {
                   11093:        /* If line starts with a # it is a comment */
                   11094:        if (line[0] == '#') {
                   11095:          numlinepar++;
                   11096:          fputs(line,stdout);
                   11097:          fputs(line,ficparo);
1.238     brouard  11098:          fputs(line,ficres);
1.230     brouard  11099:          fputs(line,ficlog);
                   11100:          continue;
                   11101:        }else
                   11102:          break;
                   11103:       }
                   11104:       if (feof(ficpar))
                   11105:        break;
                   11106:       else{ /* Processess output results for this combination of covariate values */
                   11107:       }                                   
1.240     brouard  11108:     } /* end while */
1.230     brouard  11109: 
                   11110: 
1.126     brouard  11111:     
1.230     brouard  11112:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  11113:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  11114:     
                   11115:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  11116:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  11117:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11118: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11119: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  11120:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11121: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11122: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11123:     }else{
1.218     brouard  11124:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p);
1.220     brouard  11125:     }
                   11126:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.225     brouard  11127:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,prevfcast,backcast, estepm, \
                   11128:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  11129:                
1.225     brouard  11130:     /*------------ free_vector  -------------*/
                   11131:     /*  chdir(path); */
1.220     brouard  11132:                
1.215     brouard  11133:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   11134:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   11135:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   11136:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  11137:     free_lvector(num,1,n);
                   11138:     free_vector(agedc,1,n);
                   11139:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   11140:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   11141:     fclose(ficparo);
                   11142:     fclose(ficres);
1.220     brouard  11143:                
                   11144:                
1.186     brouard  11145:     /* Other results (useful)*/
1.220     brouard  11146:                
                   11147:                
1.126     brouard  11148:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  11149:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   11150:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  11151:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  11152:     fclose(ficrespl);
                   11153: 
                   11154:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  11155:     /*#include "hpijx.h"*/
                   11156:     hPijx(p, bage, fage);
1.145     brouard  11157:     fclose(ficrespij);
1.227     brouard  11158:     
1.220     brouard  11159:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  11160:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  11161:     k=1;
1.126     brouard  11162:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  11163:     
1.219     brouard  11164:     /* Prevalence for each covariates in probs[age][status][cov] */
1.218     brouard  11165:     probs= ma3x(1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.126     brouard  11166:     for(i=1;i<=AGESUP;i++)
1.219     brouard  11167:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  11168:        for(k=1;k<=ncovcombmax;k++)
                   11169:          probs[i][j][k]=0.;
1.219     brouard  11170:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
                   11171:     if (mobilav!=0 ||mobilavproj !=0 ) {
                   11172:       mobaverages= ma3x(1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.227     brouard  11173:       for(i=1;i<=AGESUP;i++)
                   11174:        for(j=1;j<=nlstate;j++)
                   11175:          for(k=1;k<=ncovcombmax;k++)
                   11176:            mobaverages[i][j][k]=0.;
1.219     brouard  11177:       mobaverage=mobaverages;
                   11178:       if (mobilav!=0) {
1.235     brouard  11179:        printf("Movingaveraging observed prevalence\n");
1.227     brouard  11180:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   11181:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   11182:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   11183:        }
1.219     brouard  11184:       }
                   11185:       /* /\* Prevalence for each covariates in probs[age][status][cov] *\/ */
                   11186:       /* prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   11187:       else if (mobilavproj !=0) {
1.235     brouard  11188:        printf("Movingaveraging projected observed prevalence\n");
1.227     brouard  11189:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   11190:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11191:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11192:        }
1.219     brouard  11193:       }
                   11194:     }/* end if moving average */
1.227     brouard  11195:     
1.126     brouard  11196:     /*---------- Forecasting ------------------*/
                   11197:     /*if((stepm == 1) && (strcmp(model,".")==0)){*/
                   11198:     if(prevfcast==1){
                   11199:       /*    if(stepm ==1){*/
1.225     brouard  11200:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  11201:     }
1.217     brouard  11202:     if(backcast==1){
1.219     brouard  11203:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11204:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11205:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   11206: 
                   11207:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   11208: 
                   11209:       bprlim=matrix(1,nlstate,1,nlstate);
                   11210:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   11211:       fclose(ficresplb);
                   11212: 
1.222     brouard  11213:       hBijx(p, bage, fage, mobaverage);
                   11214:       fclose(ficrespijb);
1.219     brouard  11215:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11216: 
                   11217:       /* prevbackforecast(fileresu, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, mobilavproj,
1.225     brouard  11218:         bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
1.219     brouard  11219:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11220:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11221:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11222:     }
1.217     brouard  11223:     
1.186     brouard  11224:  
                   11225:     /* ------ Other prevalence ratios------------ */
1.126     brouard  11226: 
1.215     brouard  11227:     free_ivector(wav,1,imx);
                   11228:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   11229:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   11230:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  11231:                
                   11232:                
1.127     brouard  11233:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  11234:                
1.201     brouard  11235:     strcpy(filerese,"E_");
                   11236:     strcat(filerese,fileresu);
1.126     brouard  11237:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   11238:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11239:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11240:     }
1.208     brouard  11241:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   11242:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  11243: 
                   11244:     pstamp(ficreseij);
1.219     brouard  11245:                
1.235     brouard  11246:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11247:     if (cptcovn < 1){i1=1;}
                   11248:     
                   11249:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11250:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
                   11251:       if(TKresult[nres]!= k)
                   11252:        continue;
1.219     brouard  11253:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  11254:       printf("\n#****** ");
1.225     brouard  11255:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11256:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11257:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11258:       }
                   11259:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11260:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11261:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  11262:       }
                   11263:       fprintf(ficreseij,"******\n");
1.235     brouard  11264:       printf("******\n");
1.219     brouard  11265:       
                   11266:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11267:       oldm=oldms;savm=savms;
1.235     brouard  11268:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  11269:       
1.219     brouard  11270:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  11271:     }
                   11272:     fclose(ficreseij);
1.208     brouard  11273:     printf("done evsij\n");fflush(stdout);
                   11274:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.218     brouard  11275:                
1.227     brouard  11276:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  11277:                
                   11278:                
1.201     brouard  11279:     strcpy(filerest,"T_");
                   11280:     strcat(filerest,fileresu);
1.127     brouard  11281:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   11282:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   11283:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   11284:     }
1.208     brouard  11285:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   11286:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.218     brouard  11287:                
1.126     brouard  11288: 
1.201     brouard  11289:     strcpy(fileresstde,"STDE_");
                   11290:     strcat(fileresstde,fileresu);
1.126     brouard  11291:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  11292:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   11293:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  11294:     }
1.227     brouard  11295:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   11296:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  11297: 
1.201     brouard  11298:     strcpy(filerescve,"CVE_");
                   11299:     strcat(filerescve,fileresu);
1.126     brouard  11300:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  11301:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   11302:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  11303:     }
1.227     brouard  11304:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   11305:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  11306: 
1.201     brouard  11307:     strcpy(fileresv,"V_");
                   11308:     strcat(fileresv,fileresu);
1.126     brouard  11309:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   11310:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11311:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11312:     }
1.227     brouard  11313:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   11314:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  11315: 
1.145     brouard  11316:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11317:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   11318:           
1.235     brouard  11319:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11320:     if (cptcovn < 1){i1=1;}
                   11321:     
                   11322:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11323:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
                   11324:       if(TKresult[nres]!= k)
                   11325:        continue;
1.242     brouard  11326:       printf("\n#****** Result for:");
                   11327:       fprintf(ficrest,"\n#****** Result for:");
                   11328:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  11329:       for(j=1;j<=cptcoveff;j++){ 
                   11330:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11331:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11332:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11333:       }
1.235     brouard  11334:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11335:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11336:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11337:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11338:       }        
1.208     brouard  11339:       fprintf(ficrest,"******\n");
1.227     brouard  11340:       fprintf(ficlog,"******\n");
                   11341:       printf("******\n");
1.208     brouard  11342:       
                   11343:       fprintf(ficresstdeij,"\n#****** ");
                   11344:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  11345:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11346:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11347:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  11348:       }
1.235     brouard  11349:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11350:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11351:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11352:       }        
1.208     brouard  11353:       fprintf(ficresstdeij,"******\n");
                   11354:       fprintf(ficrescveij,"******\n");
                   11355:       
                   11356:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  11357:       /* pstamp(ficresvij); */
1.225     brouard  11358:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  11359:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11360:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11361:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11362:       }        
1.208     brouard  11363:       fprintf(ficresvij,"******\n");
                   11364:       
                   11365:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11366:       oldm=oldms;savm=savms;
1.235     brouard  11367:       printf(" cvevsij ");
                   11368:       fprintf(ficlog, " cvevsij ");
                   11369:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  11370:       printf(" end cvevsij \n ");
                   11371:       fprintf(ficlog, " end cvevsij \n ");
                   11372:       
                   11373:       /*
                   11374:        */
                   11375:       /* goto endfree; */
                   11376:       
                   11377:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11378:       pstamp(ficrest);
                   11379:       
                   11380:       
                   11381:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  11382:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   11383:        cptcod= 0; /* To be deleted */
                   11384:        printf("varevsij vpopbased=%d \n",vpopbased);
                   11385:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  11386:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  11387:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   11388:        if(vpopbased==1)
                   11389:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   11390:        else
                   11391:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   11392:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   11393:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   11394:        fprintf(ficrest,"\n");
                   11395:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   11396:        epj=vector(1,nlstate+1);
                   11397:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   11398:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   11399:        for(age=bage; age <=fage ;age++){
1.235     brouard  11400:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  11401:          if (vpopbased==1) {
                   11402:            if(mobilav ==0){
                   11403:              for(i=1; i<=nlstate;i++)
                   11404:                prlim[i][i]=probs[(int)age][i][k];
                   11405:            }else{ /* mobilav */ 
                   11406:              for(i=1; i<=nlstate;i++)
                   11407:                prlim[i][i]=mobaverage[(int)age][i][k];
                   11408:            }
                   11409:          }
1.219     brouard  11410:          
1.227     brouard  11411:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   11412:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   11413:          /* printf(" age %4.0f ",age); */
                   11414:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   11415:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   11416:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   11417:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   11418:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   11419:            }
                   11420:            epj[nlstate+1] +=epj[j];
                   11421:          }
                   11422:          /* printf(" age %4.0f \n",age); */
1.219     brouard  11423:          
1.227     brouard  11424:          for(i=1, vepp=0.;i <=nlstate;i++)
                   11425:            for(j=1;j <=nlstate;j++)
                   11426:              vepp += vareij[i][j][(int)age];
                   11427:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   11428:          for(j=1;j <=nlstate;j++){
                   11429:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   11430:          }
                   11431:          fprintf(ficrest,"\n");
                   11432:        }
1.208     brouard  11433:       } /* End vpopbased */
                   11434:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11435:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11436:       free_vector(epj,1,nlstate+1);
1.235     brouard  11437:       printf("done selection\n");fflush(stdout);
                   11438:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  11439:       
1.145     brouard  11440:       /*}*/
1.235     brouard  11441:     } /* End k selection */
1.227     brouard  11442: 
                   11443:     printf("done State-specific expectancies\n");fflush(stdout);
                   11444:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   11445: 
1.126     brouard  11446:     /*------- Variance of period (stable) prevalence------*/   
1.227     brouard  11447:     
1.201     brouard  11448:     strcpy(fileresvpl,"VPL_");
                   11449:     strcat(fileresvpl,fileresu);
1.126     brouard  11450:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   11451:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   11452:       exit(0);
                   11453:     }
1.208     brouard  11454:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   11455:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.227     brouard  11456:     
1.145     brouard  11457:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11458:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
1.227     brouard  11459:     
1.235     brouard  11460:     i1=pow(2,cptcoveff);
                   11461:     if (cptcovn < 1){i1=1;}
                   11462: 
                   11463:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11464:     for(k=1; k<=i1;k++){
                   11465:       if(TKresult[nres]!= k)
                   11466:        continue;
1.227     brouard  11467:       fprintf(ficresvpl,"\n#****** ");
                   11468:       printf("\n#****** ");
                   11469:       fprintf(ficlog,"\n#****** ");
                   11470:       for(j=1;j<=cptcoveff;j++) {
                   11471:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11472:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11473:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11474:       }
1.235     brouard  11475:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11476:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11477:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11478:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11479:       }        
1.227     brouard  11480:       fprintf(ficresvpl,"******\n");
                   11481:       printf("******\n");
                   11482:       fprintf(ficlog,"******\n");
                   11483:       
                   11484:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   11485:       oldm=oldms;savm=savms;
1.235     brouard  11486:       varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, strstart, nres);
1.227     brouard  11487:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
1.145     brouard  11488:       /*}*/
1.126     brouard  11489:     }
1.227     brouard  11490:     
1.126     brouard  11491:     fclose(ficresvpl);
1.208     brouard  11492:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   11493:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
1.227     brouard  11494:     
                   11495:     free_vector(weight,1,n);
                   11496:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   11497:     free_imatrix(s,1,maxwav+1,1,n);
                   11498:     free_matrix(anint,1,maxwav,1,n); 
                   11499:     free_matrix(mint,1,maxwav,1,n);
                   11500:     free_ivector(cod,1,n);
                   11501:     free_ivector(tab,1,NCOVMAX);
                   11502:     fclose(ficresstdeij);
                   11503:     fclose(ficrescveij);
                   11504:     fclose(ficresvij);
                   11505:     fclose(ficrest);
                   11506:     fclose(ficpar);
                   11507:     
                   11508:     
1.126     brouard  11509:     /*---------- End : free ----------------*/
1.219     brouard  11510:     if (mobilav!=0 ||mobilavproj !=0)
                   11511:       free_ma3x(mobaverages,1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
1.218     brouard  11512:     free_ma3x(probs,1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  11513:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11514:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  11515:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  11516:   /* endfree:*/
                   11517:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11518:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11519:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11520:   free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
1.233     brouard  11521:   free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
1.227     brouard  11522:   free_matrix(coqvar,1,maxwav,1,n);
                   11523:   free_matrix(covar,0,NCOVMAX,1,n);
                   11524:   free_matrix(matcov,1,npar,1,npar);
                   11525:   free_matrix(hess,1,npar,1,npar);
                   11526:   /*free_vector(delti,1,npar);*/
                   11527:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11528:   free_matrix(agev,1,maxwav,1,imx);
                   11529:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   11530:   
                   11531:   free_ivector(ncodemax,1,NCOVMAX);
                   11532:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   11533:   free_ivector(Dummy,-1,NCOVMAX);
                   11534:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  11535:   free_ivector(DummyV,1,NCOVMAX);
                   11536:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  11537:   free_ivector(Typevar,-1,NCOVMAX);
                   11538:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  11539:   free_ivector(TvarsQ,1,NCOVMAX);
                   11540:   free_ivector(TvarsQind,1,NCOVMAX);
                   11541:   free_ivector(TvarsD,1,NCOVMAX);
                   11542:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  11543:   free_ivector(TvarFD,1,NCOVMAX);
                   11544:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  11545:   free_ivector(TvarF,1,NCOVMAX);
                   11546:   free_ivector(TvarFind,1,NCOVMAX);
                   11547:   free_ivector(TvarV,1,NCOVMAX);
                   11548:   free_ivector(TvarVind,1,NCOVMAX);
                   11549:   free_ivector(TvarA,1,NCOVMAX);
                   11550:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  11551:   free_ivector(TvarFQ,1,NCOVMAX);
                   11552:   free_ivector(TvarFQind,1,NCOVMAX);
                   11553:   free_ivector(TvarVD,1,NCOVMAX);
                   11554:   free_ivector(TvarVDind,1,NCOVMAX);
                   11555:   free_ivector(TvarVQ,1,NCOVMAX);
                   11556:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  11557:   free_ivector(Tvarsel,1,NCOVMAX);
                   11558:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  11559:   free_ivector(Tposprod,1,NCOVMAX);
                   11560:   free_ivector(Tprod,1,NCOVMAX);
                   11561:   free_ivector(Tvaraff,1,NCOVMAX);
                   11562:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   11563:   free_ivector(Tage,1,NCOVMAX);
                   11564:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  11565:   free_ivector(TmodelInvind,1,NCOVMAX);
                   11566:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  11567:   
                   11568:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   11569:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  11570:   fflush(fichtm);
                   11571:   fflush(ficgp);
                   11572:   
1.227     brouard  11573:   
1.126     brouard  11574:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  11575:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   11576:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  11577:   }else{
                   11578:     printf("End of Imach\n");
                   11579:     fprintf(ficlog,"End of Imach\n");
                   11580:   }
                   11581:   printf("See log file on %s\n",filelog);
                   11582:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  11583:   /*(void) gettimeofday(&end_time,&tzp);*/
                   11584:   rend_time = time(NULL);  
                   11585:   end_time = *localtime(&rend_time);
                   11586:   /* tml = *localtime(&end_time.tm_sec); */
                   11587:   strcpy(strtend,asctime(&end_time));
1.126     brouard  11588:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   11589:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  11590:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  11591:   
1.157     brouard  11592:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   11593:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   11594:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  11595:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   11596: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   11597:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11598:   fclose(fichtm);
                   11599:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11600:   fclose(fichtmcov);
                   11601:   fclose(ficgp);
                   11602:   fclose(ficlog);
                   11603:   /*------ End -----------*/
1.227     brouard  11604:   
                   11605:   
                   11606:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  11607: #ifdef WIN32
1.227     brouard  11608:   if (_chdir(pathcd) != 0)
                   11609:     printf("Can't move to directory %s!\n",path);
                   11610:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  11611: #else
1.227     brouard  11612:     if(chdir(pathcd) != 0)
                   11613:       printf("Can't move to directory %s!\n", path);
                   11614:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  11615: #endif 
1.126     brouard  11616:     printf("Current directory %s!\n",pathcd);
                   11617:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   11618:   sprintf(plotcmd,"gnuplot");
1.157     brouard  11619: #ifdef _WIN32
1.126     brouard  11620:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   11621: #endif
                   11622:   if(!stat(plotcmd,&info)){
1.158     brouard  11623:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11624:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  11625:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  11626:     }else
                   11627:       strcpy(pplotcmd,plotcmd);
1.157     brouard  11628: #ifdef __unix
1.126     brouard  11629:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   11630:     if(!stat(plotcmd,&info)){
1.158     brouard  11631:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11632:     }else
                   11633:       strcpy(pplotcmd,plotcmd);
                   11634: #endif
                   11635:   }else
                   11636:     strcpy(pplotcmd,plotcmd);
                   11637:   
                   11638:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  11639:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  11640:   
1.126     brouard  11641:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  11642:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  11643:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  11644:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  11645:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  11646:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  11647:   }
1.158     brouard  11648:   printf(" Successful, please wait...");
1.126     brouard  11649:   while (z[0] != 'q') {
                   11650:     /* chdir(path); */
1.154     brouard  11651:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  11652:     scanf("%s",z);
                   11653: /*     if (z[0] == 'c') system("./imach"); */
                   11654:     if (z[0] == 'e') {
1.158     brouard  11655: #ifdef __APPLE__
1.152     brouard  11656:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  11657: #elif __linux
                   11658:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  11659: #else
1.152     brouard  11660:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  11661: #endif
                   11662:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   11663:       system(pplotcmd);
1.126     brouard  11664:     }
                   11665:     else if (z[0] == 'g') system(plotcmd);
                   11666:     else if (z[0] == 'q') exit(0);
                   11667:   }
1.227     brouard  11668: end:
1.126     brouard  11669:   while (z[0] != 'q') {
1.195     brouard  11670:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  11671:     scanf("%s",z);
                   11672:   }
                   11673: }

FreeBSD-CVSweb <freebsd-cvsweb@FreeBSD.org>