Annotation of imach/src/imach.c, revision 1.253

1.253   ! brouard     1: /* $Id: imach.c,v 1.252 2016/09/15 21:15:37 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.253   ! brouard     4:   Revision 1.252  2016/09/15 21:15:37  brouard
        !             5:   *** empty log message ***
        !             6: 
1.252     brouard     7:   Revision 1.251  2016/09/15 15:01:13  brouard
                      8:   Summary: not working
                      9: 
1.251     brouard    10:   Revision 1.250  2016/09/08 16:07:27  brouard
                     11:   Summary: continue
                     12: 
1.250     brouard    13:   Revision 1.249  2016/09/07 17:14:18  brouard
                     14:   Summary: Starting values from frequencies
                     15: 
1.249     brouard    16:   Revision 1.248  2016/09/07 14:10:18  brouard
                     17:   *** empty log message ***
                     18: 
1.248     brouard    19:   Revision 1.247  2016/09/02 11:11:21  brouard
                     20:   *** empty log message ***
                     21: 
1.247     brouard    22:   Revision 1.246  2016/09/02 08:49:22  brouard
                     23:   *** empty log message ***
                     24: 
1.246     brouard    25:   Revision 1.245  2016/09/02 07:25:01  brouard
                     26:   *** empty log message ***
                     27: 
1.245     brouard    28:   Revision 1.244  2016/09/02 07:17:34  brouard
                     29:   *** empty log message ***
                     30: 
1.244     brouard    31:   Revision 1.243  2016/09/02 06:45:35  brouard
                     32:   *** empty log message ***
                     33: 
1.243     brouard    34:   Revision 1.242  2016/08/30 15:01:20  brouard
                     35:   Summary: Fixing a lots
                     36: 
1.242     brouard    37:   Revision 1.241  2016/08/29 17:17:25  brouard
                     38:   Summary: gnuplot problem in Back projection to fix
                     39: 
1.241     brouard    40:   Revision 1.240  2016/08/29 07:53:18  brouard
                     41:   Summary: Better
                     42: 
1.240     brouard    43:   Revision 1.239  2016/08/26 15:51:03  brouard
                     44:   Summary: Improvement in Powell output in order to copy and paste
                     45: 
                     46:   Author:
                     47: 
1.239     brouard    48:   Revision 1.238  2016/08/26 14:23:35  brouard
                     49:   Summary: Starting tests of 0.99
                     50: 
1.238     brouard    51:   Revision 1.237  2016/08/26 09:20:19  brouard
                     52:   Summary: to valgrind
                     53: 
1.237     brouard    54:   Revision 1.236  2016/08/25 10:50:18  brouard
                     55:   *** empty log message ***
                     56: 
1.236     brouard    57:   Revision 1.235  2016/08/25 06:59:23  brouard
                     58:   *** empty log message ***
                     59: 
1.235     brouard    60:   Revision 1.234  2016/08/23 16:51:20  brouard
                     61:   *** empty log message ***
                     62: 
1.234     brouard    63:   Revision 1.233  2016/08/23 07:40:50  brouard
                     64:   Summary: not working
                     65: 
1.233     brouard    66:   Revision 1.232  2016/08/22 14:20:21  brouard
                     67:   Summary: not working
                     68: 
1.232     brouard    69:   Revision 1.231  2016/08/22 07:17:15  brouard
                     70:   Summary: not working
                     71: 
1.231     brouard    72:   Revision 1.230  2016/08/22 06:55:53  brouard
                     73:   Summary: Not working
                     74: 
1.230     brouard    75:   Revision 1.229  2016/07/23 09:45:53  brouard
                     76:   Summary: Completing for func too
                     77: 
1.229     brouard    78:   Revision 1.228  2016/07/22 17:45:30  brouard
                     79:   Summary: Fixing some arrays, still debugging
                     80: 
1.227     brouard    81:   Revision 1.226  2016/07/12 18:42:34  brouard
                     82:   Summary: temp
                     83: 
1.226     brouard    84:   Revision 1.225  2016/07/12 08:40:03  brouard
                     85:   Summary: saving but not running
                     86: 
1.225     brouard    87:   Revision 1.224  2016/07/01 13:16:01  brouard
                     88:   Summary: Fixes
                     89: 
1.224     brouard    90:   Revision 1.223  2016/02/19 09:23:35  brouard
                     91:   Summary: temporary
                     92: 
1.223     brouard    93:   Revision 1.222  2016/02/17 08:14:50  brouard
                     94:   Summary: Probably last 0.98 stable version 0.98r6
                     95: 
1.222     brouard    96:   Revision 1.221  2016/02/15 23:35:36  brouard
                     97:   Summary: minor bug
                     98: 
1.220     brouard    99:   Revision 1.219  2016/02/15 00:48:12  brouard
                    100:   *** empty log message ***
                    101: 
1.219     brouard   102:   Revision 1.218  2016/02/12 11:29:23  brouard
                    103:   Summary: 0.99 Back projections
                    104: 
1.218     brouard   105:   Revision 1.217  2015/12/23 17:18:31  brouard
                    106:   Summary: Experimental backcast
                    107: 
1.217     brouard   108:   Revision 1.216  2015/12/18 17:32:11  brouard
                    109:   Summary: 0.98r4 Warning and status=-2
                    110: 
                    111:   Version 0.98r4 is now:
                    112:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    113:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    114:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    115: 
1.216     brouard   116:   Revision 1.215  2015/12/16 08:52:24  brouard
                    117:   Summary: 0.98r4 working
                    118: 
1.215     brouard   119:   Revision 1.214  2015/12/16 06:57:54  brouard
                    120:   Summary: temporary not working
                    121: 
1.214     brouard   122:   Revision 1.213  2015/12/11 18:22:17  brouard
                    123:   Summary: 0.98r4
                    124: 
1.213     brouard   125:   Revision 1.212  2015/11/21 12:47:24  brouard
                    126:   Summary: minor typo
                    127: 
1.212     brouard   128:   Revision 1.211  2015/11/21 12:41:11  brouard
                    129:   Summary: 0.98r3 with some graph of projected cross-sectional
                    130: 
                    131:   Author: Nicolas Brouard
                    132: 
1.211     brouard   133:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   134:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   135:   Summary: Adding ftolpl parameter
                    136:   Author: N Brouard
                    137: 
                    138:   We had difficulties to get smoothed confidence intervals. It was due
                    139:   to the period prevalence which wasn't computed accurately. The inner
                    140:   parameter ftolpl is now an outer parameter of the .imach parameter
                    141:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    142:   computation are long.
                    143: 
1.209     brouard   144:   Revision 1.208  2015/11/17 14:31:57  brouard
                    145:   Summary: temporary
                    146: 
1.208     brouard   147:   Revision 1.207  2015/10/27 17:36:57  brouard
                    148:   *** empty log message ***
                    149: 
1.207     brouard   150:   Revision 1.206  2015/10/24 07:14:11  brouard
                    151:   *** empty log message ***
                    152: 
1.206     brouard   153:   Revision 1.205  2015/10/23 15:50:53  brouard
                    154:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    155: 
1.205     brouard   156:   Revision 1.204  2015/10/01 16:20:26  brouard
                    157:   Summary: Some new graphs of contribution to likelihood
                    158: 
1.204     brouard   159:   Revision 1.203  2015/09/30 17:45:14  brouard
                    160:   Summary: looking at better estimation of the hessian
                    161: 
                    162:   Also a better criteria for convergence to the period prevalence And
                    163:   therefore adding the number of years needed to converge. (The
                    164:   prevalence in any alive state shold sum to one
                    165: 
1.203     brouard   166:   Revision 1.202  2015/09/22 19:45:16  brouard
                    167:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    168: 
1.202     brouard   169:   Revision 1.201  2015/09/15 17:34:58  brouard
                    170:   Summary: 0.98r0
                    171: 
                    172:   - Some new graphs like suvival functions
                    173:   - Some bugs fixed like model=1+age+V2.
                    174: 
1.201     brouard   175:   Revision 1.200  2015/09/09 16:53:55  brouard
                    176:   Summary: Big bug thanks to Flavia
                    177: 
                    178:   Even model=1+age+V2. did not work anymore
                    179: 
1.200     brouard   180:   Revision 1.199  2015/09/07 14:09:23  brouard
                    181:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    182: 
1.199     brouard   183:   Revision 1.198  2015/09/03 07:14:39  brouard
                    184:   Summary: 0.98q5 Flavia
                    185: 
1.198     brouard   186:   Revision 1.197  2015/09/01 18:24:39  brouard
                    187:   *** empty log message ***
                    188: 
1.197     brouard   189:   Revision 1.196  2015/08/18 23:17:52  brouard
                    190:   Summary: 0.98q5
                    191: 
1.196     brouard   192:   Revision 1.195  2015/08/18 16:28:39  brouard
                    193:   Summary: Adding a hack for testing purpose
                    194: 
                    195:   After reading the title, ftol and model lines, if the comment line has
                    196:   a q, starting with #q, the answer at the end of the run is quit. It
                    197:   permits to run test files in batch with ctest. The former workaround was
                    198:   $ echo q | imach foo.imach
                    199: 
1.195     brouard   200:   Revision 1.194  2015/08/18 13:32:00  brouard
                    201:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    202: 
1.194     brouard   203:   Revision 1.193  2015/08/04 07:17:42  brouard
                    204:   Summary: 0.98q4
                    205: 
1.193     brouard   206:   Revision 1.192  2015/07/16 16:49:02  brouard
                    207:   Summary: Fixing some outputs
                    208: 
1.192     brouard   209:   Revision 1.191  2015/07/14 10:00:33  brouard
                    210:   Summary: Some fixes
                    211: 
1.191     brouard   212:   Revision 1.190  2015/05/05 08:51:13  brouard
                    213:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    214: 
                    215:   Fix 1+age+.
                    216: 
1.190     brouard   217:   Revision 1.189  2015/04/30 14:45:16  brouard
                    218:   Summary: 0.98q2
                    219: 
1.189     brouard   220:   Revision 1.188  2015/04/30 08:27:53  brouard
                    221:   *** empty log message ***
                    222: 
1.188     brouard   223:   Revision 1.187  2015/04/29 09:11:15  brouard
                    224:   *** empty log message ***
                    225: 
1.187     brouard   226:   Revision 1.186  2015/04/23 12:01:52  brouard
                    227:   Summary: V1*age is working now, version 0.98q1
                    228: 
                    229:   Some codes had been disabled in order to simplify and Vn*age was
                    230:   working in the optimization phase, ie, giving correct MLE parameters,
                    231:   but, as usual, outputs were not correct and program core dumped.
                    232: 
1.186     brouard   233:   Revision 1.185  2015/03/11 13:26:42  brouard
                    234:   Summary: Inclusion of compile and links command line for Intel Compiler
                    235: 
1.185     brouard   236:   Revision 1.184  2015/03/11 11:52:39  brouard
                    237:   Summary: Back from Windows 8. Intel Compiler
                    238: 
1.184     brouard   239:   Revision 1.183  2015/03/10 20:34:32  brouard
                    240:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    241: 
                    242:   We use directest instead of original Powell test; probably no
                    243:   incidence on the results, but better justifications;
                    244:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    245:   wrong results.
                    246: 
1.183     brouard   247:   Revision 1.182  2015/02/12 08:19:57  brouard
                    248:   Summary: Trying to keep directest which seems simpler and more general
                    249:   Author: Nicolas Brouard
                    250: 
1.182     brouard   251:   Revision 1.181  2015/02/11 23:22:24  brouard
                    252:   Summary: Comments on Powell added
                    253: 
                    254:   Author:
                    255: 
1.181     brouard   256:   Revision 1.180  2015/02/11 17:33:45  brouard
                    257:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    258: 
1.180     brouard   259:   Revision 1.179  2015/01/04 09:57:06  brouard
                    260:   Summary: back to OS/X
                    261: 
1.179     brouard   262:   Revision 1.178  2015/01/04 09:35:48  brouard
                    263:   *** empty log message ***
                    264: 
1.178     brouard   265:   Revision 1.177  2015/01/03 18:40:56  brouard
                    266:   Summary: Still testing ilc32 on OSX
                    267: 
1.177     brouard   268:   Revision 1.176  2015/01/03 16:45:04  brouard
                    269:   *** empty log message ***
                    270: 
1.176     brouard   271:   Revision 1.175  2015/01/03 16:33:42  brouard
                    272:   *** empty log message ***
                    273: 
1.175     brouard   274:   Revision 1.174  2015/01/03 16:15:49  brouard
                    275:   Summary: Still in cross-compilation
                    276: 
1.174     brouard   277:   Revision 1.173  2015/01/03 12:06:26  brouard
                    278:   Summary: trying to detect cross-compilation
                    279: 
1.173     brouard   280:   Revision 1.172  2014/12/27 12:07:47  brouard
                    281:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    282: 
1.172     brouard   283:   Revision 1.171  2014/12/23 13:26:59  brouard
                    284:   Summary: Back from Visual C
                    285: 
                    286:   Still problem with utsname.h on Windows
                    287: 
1.171     brouard   288:   Revision 1.170  2014/12/23 11:17:12  brouard
                    289:   Summary: Cleaning some \%% back to %%
                    290: 
                    291:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    292: 
1.170     brouard   293:   Revision 1.169  2014/12/22 23:08:31  brouard
                    294:   Summary: 0.98p
                    295: 
                    296:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    297: 
1.169     brouard   298:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   299:   Summary: update
1.169     brouard   300: 
1.168     brouard   301:   Revision 1.167  2014/12/22 13:50:56  brouard
                    302:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    303: 
                    304:   Testing on Linux 64
                    305: 
1.167     brouard   306:   Revision 1.166  2014/12/22 11:40:47  brouard
                    307:   *** empty log message ***
                    308: 
1.166     brouard   309:   Revision 1.165  2014/12/16 11:20:36  brouard
                    310:   Summary: After compiling on Visual C
                    311: 
                    312:   * imach.c (Module): Merging 1.61 to 1.162
                    313: 
1.165     brouard   314:   Revision 1.164  2014/12/16 10:52:11  brouard
                    315:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    316: 
                    317:   * imach.c (Module): Merging 1.61 to 1.162
                    318: 
1.164     brouard   319:   Revision 1.163  2014/12/16 10:30:11  brouard
                    320:   * imach.c (Module): Merging 1.61 to 1.162
                    321: 
1.163     brouard   322:   Revision 1.162  2014/09/25 11:43:39  brouard
                    323:   Summary: temporary backup 0.99!
                    324: 
1.162     brouard   325:   Revision 1.1  2014/09/16 11:06:58  brouard
                    326:   Summary: With some code (wrong) for nlopt
                    327: 
                    328:   Author:
                    329: 
                    330:   Revision 1.161  2014/09/15 20:41:41  brouard
                    331:   Summary: Problem with macro SQR on Intel compiler
                    332: 
1.161     brouard   333:   Revision 1.160  2014/09/02 09:24:05  brouard
                    334:   *** empty log message ***
                    335: 
1.160     brouard   336:   Revision 1.159  2014/09/01 10:34:10  brouard
                    337:   Summary: WIN32
                    338:   Author: Brouard
                    339: 
1.159     brouard   340:   Revision 1.158  2014/08/27 17:11:51  brouard
                    341:   *** empty log message ***
                    342: 
1.158     brouard   343:   Revision 1.157  2014/08/27 16:26:55  brouard
                    344:   Summary: Preparing windows Visual studio version
                    345:   Author: Brouard
                    346: 
                    347:   In order to compile on Visual studio, time.h is now correct and time_t
                    348:   and tm struct should be used. difftime should be used but sometimes I
                    349:   just make the differences in raw time format (time(&now).
                    350:   Trying to suppress #ifdef LINUX
                    351:   Add xdg-open for __linux in order to open default browser.
                    352: 
1.157     brouard   353:   Revision 1.156  2014/08/25 20:10:10  brouard
                    354:   *** empty log message ***
                    355: 
1.156     brouard   356:   Revision 1.155  2014/08/25 18:32:34  brouard
                    357:   Summary: New compile, minor changes
                    358:   Author: Brouard
                    359: 
1.155     brouard   360:   Revision 1.154  2014/06/20 17:32:08  brouard
                    361:   Summary: Outputs now all graphs of convergence to period prevalence
                    362: 
1.154     brouard   363:   Revision 1.153  2014/06/20 16:45:46  brouard
                    364:   Summary: If 3 live state, convergence to period prevalence on same graph
                    365:   Author: Brouard
                    366: 
1.153     brouard   367:   Revision 1.152  2014/06/18 17:54:09  brouard
                    368:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    369: 
1.152     brouard   370:   Revision 1.151  2014/06/18 16:43:30  brouard
                    371:   *** empty log message ***
                    372: 
1.151     brouard   373:   Revision 1.150  2014/06/18 16:42:35  brouard
                    374:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    375:   Author: brouard
                    376: 
1.150     brouard   377:   Revision 1.149  2014/06/18 15:51:14  brouard
                    378:   Summary: Some fixes in parameter files errors
                    379:   Author: Nicolas Brouard
                    380: 
1.149     brouard   381:   Revision 1.148  2014/06/17 17:38:48  brouard
                    382:   Summary: Nothing new
                    383:   Author: Brouard
                    384: 
                    385:   Just a new packaging for OS/X version 0.98nS
                    386: 
1.148     brouard   387:   Revision 1.147  2014/06/16 10:33:11  brouard
                    388:   *** empty log message ***
                    389: 
1.147     brouard   390:   Revision 1.146  2014/06/16 10:20:28  brouard
                    391:   Summary: Merge
                    392:   Author: Brouard
                    393: 
                    394:   Merge, before building revised version.
                    395: 
1.146     brouard   396:   Revision 1.145  2014/06/10 21:23:15  brouard
                    397:   Summary: Debugging with valgrind
                    398:   Author: Nicolas Brouard
                    399: 
                    400:   Lot of changes in order to output the results with some covariates
                    401:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    402:   improve the code.
                    403:   No more memory valgrind error but a lot has to be done in order to
                    404:   continue the work of splitting the code into subroutines.
                    405:   Also, decodemodel has been improved. Tricode is still not
                    406:   optimal. nbcode should be improved. Documentation has been added in
                    407:   the source code.
                    408: 
1.144     brouard   409:   Revision 1.143  2014/01/26 09:45:38  brouard
                    410:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    411: 
                    412:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    413:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    414: 
1.143     brouard   415:   Revision 1.142  2014/01/26 03:57:36  brouard
                    416:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    417: 
                    418:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    419: 
1.142     brouard   420:   Revision 1.141  2014/01/26 02:42:01  brouard
                    421:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    422: 
1.141     brouard   423:   Revision 1.140  2011/09/02 10:37:54  brouard
                    424:   Summary: times.h is ok with mingw32 now.
                    425: 
1.140     brouard   426:   Revision 1.139  2010/06/14 07:50:17  brouard
                    427:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    428:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    429: 
1.139     brouard   430:   Revision 1.138  2010/04/30 18:19:40  brouard
                    431:   *** empty log message ***
                    432: 
1.138     brouard   433:   Revision 1.137  2010/04/29 18:11:38  brouard
                    434:   (Module): Checking covariates for more complex models
                    435:   than V1+V2. A lot of change to be done. Unstable.
                    436: 
1.137     brouard   437:   Revision 1.136  2010/04/26 20:30:53  brouard
                    438:   (Module): merging some libgsl code. Fixing computation
                    439:   of likelione (using inter/intrapolation if mle = 0) in order to
                    440:   get same likelihood as if mle=1.
                    441:   Some cleaning of code and comments added.
                    442: 
1.136     brouard   443:   Revision 1.135  2009/10/29 15:33:14  brouard
                    444:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    445: 
1.135     brouard   446:   Revision 1.134  2009/10/29 13:18:53  brouard
                    447:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    448: 
1.134     brouard   449:   Revision 1.133  2009/07/06 10:21:25  brouard
                    450:   just nforces
                    451: 
1.133     brouard   452:   Revision 1.132  2009/07/06 08:22:05  brouard
                    453:   Many tings
                    454: 
1.132     brouard   455:   Revision 1.131  2009/06/20 16:22:47  brouard
                    456:   Some dimensions resccaled
                    457: 
1.131     brouard   458:   Revision 1.130  2009/05/26 06:44:34  brouard
                    459:   (Module): Max Covariate is now set to 20 instead of 8. A
                    460:   lot of cleaning with variables initialized to 0. Trying to make
                    461:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    462: 
1.130     brouard   463:   Revision 1.129  2007/08/31 13:49:27  lievre
                    464:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    465: 
1.129     lievre    466:   Revision 1.128  2006/06/30 13:02:05  brouard
                    467:   (Module): Clarifications on computing e.j
                    468: 
1.128     brouard   469:   Revision 1.127  2006/04/28 18:11:50  brouard
                    470:   (Module): Yes the sum of survivors was wrong since
                    471:   imach-114 because nhstepm was no more computed in the age
                    472:   loop. Now we define nhstepma in the age loop.
                    473:   (Module): In order to speed up (in case of numerous covariates) we
                    474:   compute health expectancies (without variances) in a first step
                    475:   and then all the health expectancies with variances or standard
                    476:   deviation (needs data from the Hessian matrices) which slows the
                    477:   computation.
                    478:   In the future we should be able to stop the program is only health
                    479:   expectancies and graph are needed without standard deviations.
                    480: 
1.127     brouard   481:   Revision 1.126  2006/04/28 17:23:28  brouard
                    482:   (Module): Yes the sum of survivors was wrong since
                    483:   imach-114 because nhstepm was no more computed in the age
                    484:   loop. Now we define nhstepma in the age loop.
                    485:   Version 0.98h
                    486: 
1.126     brouard   487:   Revision 1.125  2006/04/04 15:20:31  lievre
                    488:   Errors in calculation of health expectancies. Age was not initialized.
                    489:   Forecasting file added.
                    490: 
                    491:   Revision 1.124  2006/03/22 17:13:53  lievre
                    492:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    493:   The log-likelihood is printed in the log file
                    494: 
                    495:   Revision 1.123  2006/03/20 10:52:43  brouard
                    496:   * imach.c (Module): <title> changed, corresponds to .htm file
                    497:   name. <head> headers where missing.
                    498: 
                    499:   * imach.c (Module): Weights can have a decimal point as for
                    500:   English (a comma might work with a correct LC_NUMERIC environment,
                    501:   otherwise the weight is truncated).
                    502:   Modification of warning when the covariates values are not 0 or
                    503:   1.
                    504:   Version 0.98g
                    505: 
                    506:   Revision 1.122  2006/03/20 09:45:41  brouard
                    507:   (Module): Weights can have a decimal point as for
                    508:   English (a comma might work with a correct LC_NUMERIC environment,
                    509:   otherwise the weight is truncated).
                    510:   Modification of warning when the covariates values are not 0 or
                    511:   1.
                    512:   Version 0.98g
                    513: 
                    514:   Revision 1.121  2006/03/16 17:45:01  lievre
                    515:   * imach.c (Module): Comments concerning covariates added
                    516: 
                    517:   * imach.c (Module): refinements in the computation of lli if
                    518:   status=-2 in order to have more reliable computation if stepm is
                    519:   not 1 month. Version 0.98f
                    520: 
                    521:   Revision 1.120  2006/03/16 15:10:38  lievre
                    522:   (Module): refinements in the computation of lli if
                    523:   status=-2 in order to have more reliable computation if stepm is
                    524:   not 1 month. Version 0.98f
                    525: 
                    526:   Revision 1.119  2006/03/15 17:42:26  brouard
                    527:   (Module): Bug if status = -2, the loglikelihood was
                    528:   computed as likelihood omitting the logarithm. Version O.98e
                    529: 
                    530:   Revision 1.118  2006/03/14 18:20:07  brouard
                    531:   (Module): varevsij Comments added explaining the second
                    532:   table of variances if popbased=1 .
                    533:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    534:   (Module): Function pstamp added
                    535:   (Module): Version 0.98d
                    536: 
                    537:   Revision 1.117  2006/03/14 17:16:22  brouard
                    538:   (Module): varevsij Comments added explaining the second
                    539:   table of variances if popbased=1 .
                    540:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    541:   (Module): Function pstamp added
                    542:   (Module): Version 0.98d
                    543: 
                    544:   Revision 1.116  2006/03/06 10:29:27  brouard
                    545:   (Module): Variance-covariance wrong links and
                    546:   varian-covariance of ej. is needed (Saito).
                    547: 
                    548:   Revision 1.115  2006/02/27 12:17:45  brouard
                    549:   (Module): One freematrix added in mlikeli! 0.98c
                    550: 
                    551:   Revision 1.114  2006/02/26 12:57:58  brouard
                    552:   (Module): Some improvements in processing parameter
                    553:   filename with strsep.
                    554: 
                    555:   Revision 1.113  2006/02/24 14:20:24  brouard
                    556:   (Module): Memory leaks checks with valgrind and:
                    557:   datafile was not closed, some imatrix were not freed and on matrix
                    558:   allocation too.
                    559: 
                    560:   Revision 1.112  2006/01/30 09:55:26  brouard
                    561:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    562: 
                    563:   Revision 1.111  2006/01/25 20:38:18  brouard
                    564:   (Module): Lots of cleaning and bugs added (Gompertz)
                    565:   (Module): Comments can be added in data file. Missing date values
                    566:   can be a simple dot '.'.
                    567: 
                    568:   Revision 1.110  2006/01/25 00:51:50  brouard
                    569:   (Module): Lots of cleaning and bugs added (Gompertz)
                    570: 
                    571:   Revision 1.109  2006/01/24 19:37:15  brouard
                    572:   (Module): Comments (lines starting with a #) are allowed in data.
                    573: 
                    574:   Revision 1.108  2006/01/19 18:05:42  lievre
                    575:   Gnuplot problem appeared...
                    576:   To be fixed
                    577: 
                    578:   Revision 1.107  2006/01/19 16:20:37  brouard
                    579:   Test existence of gnuplot in imach path
                    580: 
                    581:   Revision 1.106  2006/01/19 13:24:36  brouard
                    582:   Some cleaning and links added in html output
                    583: 
                    584:   Revision 1.105  2006/01/05 20:23:19  lievre
                    585:   *** empty log message ***
                    586: 
                    587:   Revision 1.104  2005/09/30 16:11:43  lievre
                    588:   (Module): sump fixed, loop imx fixed, and simplifications.
                    589:   (Module): If the status is missing at the last wave but we know
                    590:   that the person is alive, then we can code his/her status as -2
                    591:   (instead of missing=-1 in earlier versions) and his/her
                    592:   contributions to the likelihood is 1 - Prob of dying from last
                    593:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    594:   the healthy state at last known wave). Version is 0.98
                    595: 
                    596:   Revision 1.103  2005/09/30 15:54:49  lievre
                    597:   (Module): sump fixed, loop imx fixed, and simplifications.
                    598: 
                    599:   Revision 1.102  2004/09/15 17:31:30  brouard
                    600:   Add the possibility to read data file including tab characters.
                    601: 
                    602:   Revision 1.101  2004/09/15 10:38:38  brouard
                    603:   Fix on curr_time
                    604: 
                    605:   Revision 1.100  2004/07/12 18:29:06  brouard
                    606:   Add version for Mac OS X. Just define UNIX in Makefile
                    607: 
                    608:   Revision 1.99  2004/06/05 08:57:40  brouard
                    609:   *** empty log message ***
                    610: 
                    611:   Revision 1.98  2004/05/16 15:05:56  brouard
                    612:   New version 0.97 . First attempt to estimate force of mortality
                    613:   directly from the data i.e. without the need of knowing the health
                    614:   state at each age, but using a Gompertz model: log u =a + b*age .
                    615:   This is the basic analysis of mortality and should be done before any
                    616:   other analysis, in order to test if the mortality estimated from the
                    617:   cross-longitudinal survey is different from the mortality estimated
                    618:   from other sources like vital statistic data.
                    619: 
                    620:   The same imach parameter file can be used but the option for mle should be -3.
                    621: 
1.133     brouard   622:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   623:   former routines in order to include the new code within the former code.
                    624: 
                    625:   The output is very simple: only an estimate of the intercept and of
                    626:   the slope with 95% confident intervals.
                    627: 
                    628:   Current limitations:
                    629:   A) Even if you enter covariates, i.e. with the
                    630:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    631:   B) There is no computation of Life Expectancy nor Life Table.
                    632: 
                    633:   Revision 1.97  2004/02/20 13:25:42  lievre
                    634:   Version 0.96d. Population forecasting command line is (temporarily)
                    635:   suppressed.
                    636: 
                    637:   Revision 1.96  2003/07/15 15:38:55  brouard
                    638:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    639:   rewritten within the same printf. Workaround: many printfs.
                    640: 
                    641:   Revision 1.95  2003/07/08 07:54:34  brouard
                    642:   * imach.c (Repository):
                    643:   (Repository): Using imachwizard code to output a more meaningful covariance
                    644:   matrix (cov(a12,c31) instead of numbers.
                    645: 
                    646:   Revision 1.94  2003/06/27 13:00:02  brouard
                    647:   Just cleaning
                    648: 
                    649:   Revision 1.93  2003/06/25 16:33:55  brouard
                    650:   (Module): On windows (cygwin) function asctime_r doesn't
                    651:   exist so I changed back to asctime which exists.
                    652:   (Module): Version 0.96b
                    653: 
                    654:   Revision 1.92  2003/06/25 16:30:45  brouard
                    655:   (Module): On windows (cygwin) function asctime_r doesn't
                    656:   exist so I changed back to asctime which exists.
                    657: 
                    658:   Revision 1.91  2003/06/25 15:30:29  brouard
                    659:   * imach.c (Repository): Duplicated warning errors corrected.
                    660:   (Repository): Elapsed time after each iteration is now output. It
                    661:   helps to forecast when convergence will be reached. Elapsed time
                    662:   is stamped in powell.  We created a new html file for the graphs
                    663:   concerning matrix of covariance. It has extension -cov.htm.
                    664: 
                    665:   Revision 1.90  2003/06/24 12:34:15  brouard
                    666:   (Module): Some bugs corrected for windows. Also, when
                    667:   mle=-1 a template is output in file "or"mypar.txt with the design
                    668:   of the covariance matrix to be input.
                    669: 
                    670:   Revision 1.89  2003/06/24 12:30:52  brouard
                    671:   (Module): Some bugs corrected for windows. Also, when
                    672:   mle=-1 a template is output in file "or"mypar.txt with the design
                    673:   of the covariance matrix to be input.
                    674: 
                    675:   Revision 1.88  2003/06/23 17:54:56  brouard
                    676:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    677: 
                    678:   Revision 1.87  2003/06/18 12:26:01  brouard
                    679:   Version 0.96
                    680: 
                    681:   Revision 1.86  2003/06/17 20:04:08  brouard
                    682:   (Module): Change position of html and gnuplot routines and added
                    683:   routine fileappend.
                    684: 
                    685:   Revision 1.85  2003/06/17 13:12:43  brouard
                    686:   * imach.c (Repository): Check when date of death was earlier that
                    687:   current date of interview. It may happen when the death was just
                    688:   prior to the death. In this case, dh was negative and likelihood
                    689:   was wrong (infinity). We still send an "Error" but patch by
                    690:   assuming that the date of death was just one stepm after the
                    691:   interview.
                    692:   (Repository): Because some people have very long ID (first column)
                    693:   we changed int to long in num[] and we added a new lvector for
                    694:   memory allocation. But we also truncated to 8 characters (left
                    695:   truncation)
                    696:   (Repository): No more line truncation errors.
                    697: 
                    698:   Revision 1.84  2003/06/13 21:44:43  brouard
                    699:   * imach.c (Repository): Replace "freqsummary" at a correct
                    700:   place. It differs from routine "prevalence" which may be called
                    701:   many times. Probs is memory consuming and must be used with
                    702:   parcimony.
                    703:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    704: 
                    705:   Revision 1.83  2003/06/10 13:39:11  lievre
                    706:   *** empty log message ***
                    707: 
                    708:   Revision 1.82  2003/06/05 15:57:20  brouard
                    709:   Add log in  imach.c and  fullversion number is now printed.
                    710: 
                    711: */
                    712: /*
                    713:    Interpolated Markov Chain
                    714: 
                    715:   Short summary of the programme:
                    716:   
1.227     brouard   717:   This program computes Healthy Life Expectancies or State-specific
                    718:   (if states aren't health statuses) Expectancies from
                    719:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    720: 
                    721:   -1- a first survey ("cross") where individuals from different ages
                    722:   are interviewed on their health status or degree of disability (in
                    723:   the case of a health survey which is our main interest)
                    724: 
                    725:   -2- at least a second wave of interviews ("longitudinal") which
                    726:   measure each change (if any) in individual health status.  Health
                    727:   expectancies are computed from the time spent in each health state
                    728:   according to a model. More health states you consider, more time is
                    729:   necessary to reach the Maximum Likelihood of the parameters involved
                    730:   in the model.  The simplest model is the multinomial logistic model
                    731:   where pij is the probability to be observed in state j at the second
                    732:   wave conditional to be observed in state i at the first
                    733:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    734:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    735:   have a more complex model than "constant and age", you should modify
                    736:   the program where the markup *Covariates have to be included here
                    737:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   738:   convergence.
                    739: 
                    740:   The advantage of this computer programme, compared to a simple
                    741:   multinomial logistic model, is clear when the delay between waves is not
                    742:   identical for each individual. Also, if a individual missed an
                    743:   intermediate interview, the information is lost, but taken into
                    744:   account using an interpolation or extrapolation.  
                    745: 
                    746:   hPijx is the probability to be observed in state i at age x+h
                    747:   conditional to the observed state i at age x. The delay 'h' can be
                    748:   split into an exact number (nh*stepm) of unobserved intermediate
                    749:   states. This elementary transition (by month, quarter,
                    750:   semester or year) is modelled as a multinomial logistic.  The hPx
                    751:   matrix is simply the matrix product of nh*stepm elementary matrices
                    752:   and the contribution of each individual to the likelihood is simply
                    753:   hPijx.
                    754: 
                    755:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   756:   of the life expectancies. It also computes the period (stable) prevalence.
                    757: 
                    758: Back prevalence and projections:
1.227     brouard   759: 
                    760:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    761:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    762:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    763:    mobilavproj)
                    764: 
                    765:     Computes the back prevalence limit for any combination of
                    766:     covariate values k at any age between ageminpar and agemaxpar and
                    767:     returns it in **bprlim. In the loops,
                    768: 
                    769:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    770:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    771: 
                    772:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   773:    Computes for any combination of covariates k and any age between bage and fage 
                    774:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    775:                        oldm=oldms;savm=savms;
1.227     brouard   776: 
                    777:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);
1.218     brouard   778:      Computes the transition matrix starting at age 'age' over
                    779:      'nhstepm*hstepm*stepm' months (i.e. until
                    780:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   781:      nhstepm*hstepm matrices. 
                    782: 
                    783:      Returns p3mat[i][j][h] after calling
                    784:      p3mat[i][j][h]=matprod2(newm,
                    785:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    786:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    787:      oldm);
1.226     brouard   788: 
                    789: Important routines
                    790: 
                    791: - func (or funcone), computes logit (pij) distinguishing
                    792:   o fixed variables (single or product dummies or quantitative);
                    793:   o varying variables by:
                    794:    (1) wave (single, product dummies, quantitative), 
                    795:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    796:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    797:        % varying dummy (not done) or quantitative (not done);
                    798: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    799:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    800: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    801:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    802:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   803: 
1.226     brouard   804: 
                    805:   
1.133     brouard   806:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    807:            Institut national d'études démographiques, Paris.
1.126     brouard   808:   This software have been partly granted by Euro-REVES, a concerted action
                    809:   from the European Union.
                    810:   It is copyrighted identically to a GNU software product, ie programme and
                    811:   software can be distributed freely for non commercial use. Latest version
                    812:   can be accessed at http://euroreves.ined.fr/imach .
                    813: 
                    814:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    815:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    816:   
                    817:   **********************************************************************/
                    818: /*
                    819:   main
                    820:   read parameterfile
                    821:   read datafile
                    822:   concatwav
                    823:   freqsummary
                    824:   if (mle >= 1)
                    825:     mlikeli
                    826:   print results files
                    827:   if mle==1 
                    828:      computes hessian
                    829:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    830:       begin-prev-date,...
                    831:   open gnuplot file
                    832:   open html file
1.145     brouard   833:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    834:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    835:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    836:     freexexit2 possible for memory heap.
                    837: 
                    838:   h Pij x                         | pij_nom  ficrestpij
                    839:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    840:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    841:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    842: 
                    843:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    844:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    845:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    846:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    847:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    848: 
1.126     brouard   849:   forecasting if prevfcast==1 prevforecast call prevalence()
                    850:   health expectancies
                    851:   Variance-covariance of DFLE
                    852:   prevalence()
                    853:    movingaverage()
                    854:   varevsij() 
                    855:   if popbased==1 varevsij(,popbased)
                    856:   total life expectancies
                    857:   Variance of period (stable) prevalence
                    858:  end
                    859: */
                    860: 
1.187     brouard   861: /* #define DEBUG */
                    862: /* #define DEBUGBRENT */
1.203     brouard   863: /* #define DEBUGLINMIN */
                    864: /* #define DEBUGHESS */
                    865: #define DEBUGHESSIJ
1.224     brouard   866: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   867: #define POWELL /* Instead of NLOPT */
1.224     brouard   868: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   869: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    870: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   871: 
                    872: #include <math.h>
                    873: #include <stdio.h>
                    874: #include <stdlib.h>
                    875: #include <string.h>
1.226     brouard   876: #include <ctype.h>
1.159     brouard   877: 
                    878: #ifdef _WIN32
                    879: #include <io.h>
1.172     brouard   880: #include <windows.h>
                    881: #include <tchar.h>
1.159     brouard   882: #else
1.126     brouard   883: #include <unistd.h>
1.159     brouard   884: #endif
1.126     brouard   885: 
                    886: #include <limits.h>
                    887: #include <sys/types.h>
1.171     brouard   888: 
                    889: #if defined(__GNUC__)
                    890: #include <sys/utsname.h> /* Doesn't work on Windows */
                    891: #endif
                    892: 
1.126     brouard   893: #include <sys/stat.h>
                    894: #include <errno.h>
1.159     brouard   895: /* extern int errno; */
1.126     brouard   896: 
1.157     brouard   897: /* #ifdef LINUX */
                    898: /* #include <time.h> */
                    899: /* #include "timeval.h" */
                    900: /* #else */
                    901: /* #include <sys/time.h> */
                    902: /* #endif */
                    903: 
1.126     brouard   904: #include <time.h>
                    905: 
1.136     brouard   906: #ifdef GSL
                    907: #include <gsl/gsl_errno.h>
                    908: #include <gsl/gsl_multimin.h>
                    909: #endif
                    910: 
1.167     brouard   911: 
1.162     brouard   912: #ifdef NLOPT
                    913: #include <nlopt.h>
                    914: typedef struct {
                    915:   double (* function)(double [] );
                    916: } myfunc_data ;
                    917: #endif
                    918: 
1.126     brouard   919: /* #include <libintl.h> */
                    920: /* #define _(String) gettext (String) */
                    921: 
1.251     brouard   922: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   923: 
                    924: #define GNUPLOTPROGRAM "gnuplot"
                    925: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    926: #define FILENAMELENGTH 132
                    927: 
                    928: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    929: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    930: 
1.144     brouard   931: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    932: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   933: 
                    934: #define NINTERVMAX 8
1.144     brouard   935: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    936: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    937: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   938: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   939: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    940: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   941: #define MAXN 20000
1.144     brouard   942: #define YEARM 12. /**< Number of months per year */
1.218     brouard   943: /* #define AGESUP 130 */
                    944: #define AGESUP 150
                    945: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard   946: #define AGEBASE 40
1.194     brouard   947: #define AGEOVERFLOW 1.e20
1.164     brouard   948: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard   949: #ifdef _WIN32
                    950: #define DIRSEPARATOR '\\'
                    951: #define CHARSEPARATOR "\\"
                    952: #define ODIRSEPARATOR '/'
                    953: #else
1.126     brouard   954: #define DIRSEPARATOR '/'
                    955: #define CHARSEPARATOR "/"
                    956: #define ODIRSEPARATOR '\\'
                    957: #endif
                    958: 
1.253   ! brouard   959: /* $Id: imach.c,v 1.252 2016/09/15 21:15:37 brouard Exp $ */
1.126     brouard   960: /* $State: Exp $ */
1.196     brouard   961: #include "version.h"
                    962: char version[]=__IMACH_VERSION__;
1.224     brouard   963: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.253   ! brouard   964: char fullversion[]="$Revision: 1.252 $ $Date: 2016/09/15 21:15:37 $"; 
1.126     brouard   965: char strstart[80];
                    966: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard   967: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard   968: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard   969: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                    970: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                    971: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard   972: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                    973: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard   974: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                    975: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                    976: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard   977: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                    978: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard   979: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard   980: int nsd=0; /**< Total number of single dummy variables (output) */
                    981: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard   982: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard   983: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard   984: int ntveff=0; /**< ntveff number of effective time varying variables */
                    985: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard   986: int cptcov=0; /* Working variable */
1.218     brouard   987: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard   988: int npar=NPARMAX;
                    989: int nlstate=2; /* Number of live states */
                    990: int ndeath=1; /* Number of dead states */
1.130     brouard   991: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard   992: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard   993: int popbased=0;
                    994: 
                    995: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard   996: int maxwav=0; /* Maxim number of waves */
                    997: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                    998: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                    999: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1000:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1001: int mle=1, weightopt=0;
1.126     brouard  1002: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1003: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1004: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1005:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1006: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1007: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1008: 
1.130     brouard  1009: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1010: double **matprod2(); /* test */
1.126     brouard  1011: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1012: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1013: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1014: 
1.136     brouard  1015: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1016: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1017: FILE *ficlog, *ficrespow;
1.130     brouard  1018: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1019: double fretone; /* Only one call to likelihood */
1.130     brouard  1020: long ipmx=0; /* Number of contributions */
1.126     brouard  1021: double sw; /* Sum of weights */
                   1022: char filerespow[FILENAMELENGTH];
                   1023: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1024: FILE *ficresilk;
                   1025: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1026: FILE *ficresprobmorprev;
                   1027: FILE *fichtm, *fichtmcov; /* Html File */
                   1028: FILE *ficreseij;
                   1029: char filerese[FILENAMELENGTH];
                   1030: FILE *ficresstdeij;
                   1031: char fileresstde[FILENAMELENGTH];
                   1032: FILE *ficrescveij;
                   1033: char filerescve[FILENAMELENGTH];
                   1034: FILE  *ficresvij;
                   1035: char fileresv[FILENAMELENGTH];
                   1036: FILE  *ficresvpl;
                   1037: char fileresvpl[FILENAMELENGTH];
                   1038: char title[MAXLINE];
1.234     brouard  1039: char model[MAXLINE]; /**< The model line */
1.217     brouard  1040: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1041: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1042: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1043: char command[FILENAMELENGTH];
                   1044: int  outcmd=0;
                   1045: 
1.217     brouard  1046: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1047: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1048: char filelog[FILENAMELENGTH]; /* Log file */
                   1049: char filerest[FILENAMELENGTH];
                   1050: char fileregp[FILENAMELENGTH];
                   1051: char popfile[FILENAMELENGTH];
                   1052: 
                   1053: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1054: 
1.157     brouard  1055: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1056: /* struct timezone tzp; */
                   1057: /* extern int gettimeofday(); */
                   1058: struct tm tml, *gmtime(), *localtime();
                   1059: 
                   1060: extern time_t time();
                   1061: 
                   1062: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1063: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1064: struct tm tm;
                   1065: 
1.126     brouard  1066: char strcurr[80], strfor[80];
                   1067: 
                   1068: char *endptr;
                   1069: long lval;
                   1070: double dval;
                   1071: 
                   1072: #define NR_END 1
                   1073: #define FREE_ARG char*
                   1074: #define FTOL 1.0e-10
                   1075: 
                   1076: #define NRANSI 
1.240     brouard  1077: #define ITMAX 200
                   1078: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1079: 
                   1080: #define TOL 2.0e-4 
                   1081: 
                   1082: #define CGOLD 0.3819660 
                   1083: #define ZEPS 1.0e-10 
                   1084: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1085: 
                   1086: #define GOLD 1.618034 
                   1087: #define GLIMIT 100.0 
                   1088: #define TINY 1.0e-20 
                   1089: 
                   1090: static double maxarg1,maxarg2;
                   1091: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1092: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1093:   
                   1094: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1095: #define rint(a) floor(a+0.5)
1.166     brouard  1096: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1097: #define mytinydouble 1.0e-16
1.166     brouard  1098: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1099: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1100: /* static double dsqrarg; */
                   1101: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1102: static double sqrarg;
                   1103: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1104: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1105: int agegomp= AGEGOMP;
                   1106: 
                   1107: int imx; 
                   1108: int stepm=1;
                   1109: /* Stepm, step in month: minimum step interpolation*/
                   1110: 
                   1111: int estepm;
                   1112: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1113: 
                   1114: int m,nb;
                   1115: long *num;
1.197     brouard  1116: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1117: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1118:                   covariate for which somebody answered excluding 
                   1119:                   undefined. Usually 2: 0 and 1. */
                   1120: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1121:                             covariate for which somebody answered including 
                   1122:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1123: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1124: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1125: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1126: double *ageexmed,*agecens;
                   1127: double dateintmean=0;
                   1128: 
                   1129: double *weight;
                   1130: int **s; /* Status */
1.141     brouard  1131: double *agedc;
1.145     brouard  1132: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1133:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1134:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.225     brouard  1135: double **coqvar; /* Fixed quantitative covariate iqv */
                   1136: double ***cotvar; /* Time varying covariate itv */
                   1137: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1138: double  idx; 
                   1139: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1140: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1141: /*k          1  2   3   4     5    6    7     8    9 */
                   1142: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1143: /* Tndvar[k]    1   2   3               4          5 */
                   1144: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1145: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1146: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1147: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1148: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1149: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1150: /* Tprod[i]=k           4               7            */
                   1151: /* Tage[i]=k                  5               8      */
                   1152: /* */
                   1153: /* Type                    */
                   1154: /* V         1  2  3  4  5 */
                   1155: /*           F  F  V  V  V */
                   1156: /*           D  Q  D  D  Q */
                   1157: /*                         */
                   1158: int *TvarsD;
                   1159: int *TvarsDind;
                   1160: int *TvarsQ;
                   1161: int *TvarsQind;
                   1162: 
1.235     brouard  1163: #define MAXRESULTLINES 10
                   1164: int nresult=0;
                   1165: int TKresult[MAXRESULTLINES];
1.237     brouard  1166: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1167: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1168: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1169: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1170: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1171: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1172: 
1.234     brouard  1173: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1174: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1175: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1176: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1177: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1178: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1179: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1180: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1181: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1182: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1183: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1184: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1185: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1186: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1187: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1188: 
1.230     brouard  1189: int *Tvarsel; /**< Selected covariates for output */
                   1190: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1191: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1192: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1193: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1194: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1195: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1196: int *Tage;
1.227     brouard  1197: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1198: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1199: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1200: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1201: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1202: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1203: int **Tvard;
                   1204: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1205: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1206: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1207:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1208:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1209: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1210: double *lsurv, *lpop, *tpop;
                   1211: 
1.231     brouard  1212: #define FD 1; /* Fixed dummy covariate */
                   1213: #define FQ 2; /* Fixed quantitative covariate */
                   1214: #define FP 3; /* Fixed product covariate */
                   1215: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1216: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1217: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1218: #define VD 10; /* Varying dummy covariate */
                   1219: #define VQ 11; /* Varying quantitative covariate */
                   1220: #define VP 12; /* Varying product covariate */
                   1221: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1222: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1223: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1224: #define APFD 16; /* Age product * fixed dummy covariate */
                   1225: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1226: #define APVD 18; /* Age product * varying dummy covariate */
                   1227: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1228: 
                   1229: #define FTYPE 1; /* Fixed covariate */
                   1230: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1231: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1232: 
                   1233: struct kmodel{
                   1234:        int maintype; /* main type */
                   1235:        int subtype; /* subtype */
                   1236: };
                   1237: struct kmodel modell[NCOVMAX];
                   1238: 
1.143     brouard  1239: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1240: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1241: 
                   1242: /**************** split *************************/
                   1243: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1244: {
                   1245:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1246:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1247:   */ 
                   1248:   char *ss;                            /* pointer */
1.186     brouard  1249:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1250: 
                   1251:   l1 = strlen(path );                  /* length of path */
                   1252:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1253:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1254:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1255:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1256:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1257:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1258:     /* get current working directory */
                   1259:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1260: #ifdef WIN32
                   1261:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1262: #else
                   1263:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1264: #endif
1.126     brouard  1265:       return( GLOCK_ERROR_GETCWD );
                   1266:     }
                   1267:     /* got dirc from getcwd*/
                   1268:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1269:   } else {                             /* strip directory from path */
1.126     brouard  1270:     ss++;                              /* after this, the filename */
                   1271:     l2 = strlen( ss );                 /* length of filename */
                   1272:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1273:     strcpy( name, ss );                /* save file name */
                   1274:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1275:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1276:     printf(" DIRC2 = %s \n",dirc);
                   1277:   }
                   1278:   /* We add a separator at the end of dirc if not exists */
                   1279:   l1 = strlen( dirc );                 /* length of directory */
                   1280:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1281:     dirc[l1] =  DIRSEPARATOR;
                   1282:     dirc[l1+1] = 0; 
                   1283:     printf(" DIRC3 = %s \n",dirc);
                   1284:   }
                   1285:   ss = strrchr( name, '.' );           /* find last / */
                   1286:   if (ss >0){
                   1287:     ss++;
                   1288:     strcpy(ext,ss);                    /* save extension */
                   1289:     l1= strlen( name);
                   1290:     l2= strlen(ss)+1;
                   1291:     strncpy( finame, name, l1-l2);
                   1292:     finame[l1-l2]= 0;
                   1293:   }
                   1294: 
                   1295:   return( 0 );                         /* we're done */
                   1296: }
                   1297: 
                   1298: 
                   1299: /******************************************/
                   1300: 
                   1301: void replace_back_to_slash(char *s, char*t)
                   1302: {
                   1303:   int i;
                   1304:   int lg=0;
                   1305:   i=0;
                   1306:   lg=strlen(t);
                   1307:   for(i=0; i<= lg; i++) {
                   1308:     (s[i] = t[i]);
                   1309:     if (t[i]== '\\') s[i]='/';
                   1310:   }
                   1311: }
                   1312: 
1.132     brouard  1313: char *trimbb(char *out, char *in)
1.137     brouard  1314: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1315:   char *s;
                   1316:   s=out;
                   1317:   while (*in != '\0'){
1.137     brouard  1318:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1319:       in++;
                   1320:     }
                   1321:     *out++ = *in++;
                   1322:   }
                   1323:   *out='\0';
                   1324:   return s;
                   1325: }
                   1326: 
1.187     brouard  1327: /* char *substrchaine(char *out, char *in, char *chain) */
                   1328: /* { */
                   1329: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1330: /*   char *s, *t; */
                   1331: /*   t=in;s=out; */
                   1332: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1333: /*     *out++ = *in++; */
                   1334: /*   } */
                   1335: 
                   1336: /*   /\* *in matches *chain *\/ */
                   1337: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1338: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1339: /*   } */
                   1340: /*   in--; chain--; */
                   1341: /*   while ( (*in != '\0')){ */
                   1342: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1343: /*     *out++ = *in++; */
                   1344: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1345: /*   } */
                   1346: /*   *out='\0'; */
                   1347: /*   out=s; */
                   1348: /*   return out; */
                   1349: /* } */
                   1350: char *substrchaine(char *out, char *in, char *chain)
                   1351: {
                   1352:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1353:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1354: 
                   1355:   char *strloc;
                   1356: 
                   1357:   strcpy (out, in); 
                   1358:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1359:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1360:   if(strloc != NULL){ 
                   1361:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1362:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1363:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1364:   }
                   1365:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1366:   return out;
                   1367: }
                   1368: 
                   1369: 
1.145     brouard  1370: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1371: {
1.187     brouard  1372:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1373:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1374:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1375:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1376:   */
1.160     brouard  1377:   char *s, *t;
1.145     brouard  1378:   t=in;s=in;
                   1379:   while ((*in != occ) && (*in != '\0')){
                   1380:     *alocc++ = *in++;
                   1381:   }
                   1382:   if( *in == occ){
                   1383:     *(alocc)='\0';
                   1384:     s=++in;
                   1385:   }
                   1386:  
                   1387:   if (s == t) {/* occ not found */
                   1388:     *(alocc-(in-s))='\0';
                   1389:     in=s;
                   1390:   }
                   1391:   while ( *in != '\0'){
                   1392:     *blocc++ = *in++;
                   1393:   }
                   1394: 
                   1395:   *blocc='\0';
                   1396:   return t;
                   1397: }
1.137     brouard  1398: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1399: {
1.187     brouard  1400:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1401:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1402:      gives blocc="abcdef2ghi" and alocc="j".
                   1403:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1404:   */
                   1405:   char *s, *t;
                   1406:   t=in;s=in;
                   1407:   while (*in != '\0'){
                   1408:     while( *in == occ){
                   1409:       *blocc++ = *in++;
                   1410:       s=in;
                   1411:     }
                   1412:     *blocc++ = *in++;
                   1413:   }
                   1414:   if (s == t) /* occ not found */
                   1415:     *(blocc-(in-s))='\0';
                   1416:   else
                   1417:     *(blocc-(in-s)-1)='\0';
                   1418:   in=s;
                   1419:   while ( *in != '\0'){
                   1420:     *alocc++ = *in++;
                   1421:   }
                   1422: 
                   1423:   *alocc='\0';
                   1424:   return s;
                   1425: }
                   1426: 
1.126     brouard  1427: int nbocc(char *s, char occ)
                   1428: {
                   1429:   int i,j=0;
                   1430:   int lg=20;
                   1431:   i=0;
                   1432:   lg=strlen(s);
                   1433:   for(i=0; i<= lg; i++) {
1.234     brouard  1434:     if  (s[i] == occ ) j++;
1.126     brouard  1435:   }
                   1436:   return j;
                   1437: }
                   1438: 
1.137     brouard  1439: /* void cutv(char *u,char *v, char*t, char occ) */
                   1440: /* { */
                   1441: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1442: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1443: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1444: /*   int i,lg,j,p=0; */
                   1445: /*   i=0; */
                   1446: /*   lg=strlen(t); */
                   1447: /*   for(j=0; j<=lg-1; j++) { */
                   1448: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1449: /*   } */
1.126     brouard  1450: 
1.137     brouard  1451: /*   for(j=0; j<p; j++) { */
                   1452: /*     (u[j] = t[j]); */
                   1453: /*   } */
                   1454: /*      u[p]='\0'; */
1.126     brouard  1455: 
1.137     brouard  1456: /*    for(j=0; j<= lg; j++) { */
                   1457: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1458: /*   } */
                   1459: /* } */
1.126     brouard  1460: 
1.160     brouard  1461: #ifdef _WIN32
                   1462: char * strsep(char **pp, const char *delim)
                   1463: {
                   1464:   char *p, *q;
                   1465:          
                   1466:   if ((p = *pp) == NULL)
                   1467:     return 0;
                   1468:   if ((q = strpbrk (p, delim)) != NULL)
                   1469:   {
                   1470:     *pp = q + 1;
                   1471:     *q = '\0';
                   1472:   }
                   1473:   else
                   1474:     *pp = 0;
                   1475:   return p;
                   1476: }
                   1477: #endif
                   1478: 
1.126     brouard  1479: /********************** nrerror ********************/
                   1480: 
                   1481: void nrerror(char error_text[])
                   1482: {
                   1483:   fprintf(stderr,"ERREUR ...\n");
                   1484:   fprintf(stderr,"%s\n",error_text);
                   1485:   exit(EXIT_FAILURE);
                   1486: }
                   1487: /*********************** vector *******************/
                   1488: double *vector(int nl, int nh)
                   1489: {
                   1490:   double *v;
                   1491:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1492:   if (!v) nrerror("allocation failure in vector");
                   1493:   return v-nl+NR_END;
                   1494: }
                   1495: 
                   1496: /************************ free vector ******************/
                   1497: void free_vector(double*v, int nl, int nh)
                   1498: {
                   1499:   free((FREE_ARG)(v+nl-NR_END));
                   1500: }
                   1501: 
                   1502: /************************ivector *******************************/
                   1503: int *ivector(long nl,long nh)
                   1504: {
                   1505:   int *v;
                   1506:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1507:   if (!v) nrerror("allocation failure in ivector");
                   1508:   return v-nl+NR_END;
                   1509: }
                   1510: 
                   1511: /******************free ivector **************************/
                   1512: void free_ivector(int *v, long nl, long nh)
                   1513: {
                   1514:   free((FREE_ARG)(v+nl-NR_END));
                   1515: }
                   1516: 
                   1517: /************************lvector *******************************/
                   1518: long *lvector(long nl,long nh)
                   1519: {
                   1520:   long *v;
                   1521:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1522:   if (!v) nrerror("allocation failure in ivector");
                   1523:   return v-nl+NR_END;
                   1524: }
                   1525: 
                   1526: /******************free lvector **************************/
                   1527: void free_lvector(long *v, long nl, long nh)
                   1528: {
                   1529:   free((FREE_ARG)(v+nl-NR_END));
                   1530: }
                   1531: 
                   1532: /******************* imatrix *******************************/
                   1533: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1534:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1535: { 
                   1536:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1537:   int **m; 
                   1538:   
                   1539:   /* allocate pointers to rows */ 
                   1540:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1541:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1542:   m += NR_END; 
                   1543:   m -= nrl; 
                   1544:   
                   1545:   
                   1546:   /* allocate rows and set pointers to them */ 
                   1547:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1548:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1549:   m[nrl] += NR_END; 
                   1550:   m[nrl] -= ncl; 
                   1551:   
                   1552:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1553:   
                   1554:   /* return pointer to array of pointers to rows */ 
                   1555:   return m; 
                   1556: } 
                   1557: 
                   1558: /****************** free_imatrix *************************/
                   1559: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1560:       int **m;
                   1561:       long nch,ncl,nrh,nrl; 
                   1562:      /* free an int matrix allocated by imatrix() */ 
                   1563: { 
                   1564:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1565:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1566: } 
                   1567: 
                   1568: /******************* matrix *******************************/
                   1569: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1570: {
                   1571:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1572:   double **m;
                   1573: 
                   1574:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1575:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1576:   m += NR_END;
                   1577:   m -= nrl;
                   1578: 
                   1579:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1580:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1581:   m[nrl] += NR_END;
                   1582:   m[nrl] -= ncl;
                   1583: 
                   1584:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1585:   return m;
1.145     brouard  1586:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1587: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1588: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1589:    */
                   1590: }
                   1591: 
                   1592: /*************************free matrix ************************/
                   1593: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1594: {
                   1595:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1596:   free((FREE_ARG)(m+nrl-NR_END));
                   1597: }
                   1598: 
                   1599: /******************* ma3x *******************************/
                   1600: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1601: {
                   1602:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1603:   double ***m;
                   1604: 
                   1605:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1606:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1607:   m += NR_END;
                   1608:   m -= nrl;
                   1609: 
                   1610:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1611:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1612:   m[nrl] += NR_END;
                   1613:   m[nrl] -= ncl;
                   1614: 
                   1615:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1616: 
                   1617:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1618:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1619:   m[nrl][ncl] += NR_END;
                   1620:   m[nrl][ncl] -= nll;
                   1621:   for (j=ncl+1; j<=nch; j++) 
                   1622:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1623:   
                   1624:   for (i=nrl+1; i<=nrh; i++) {
                   1625:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1626:     for (j=ncl+1; j<=nch; j++) 
                   1627:       m[i][j]=m[i][j-1]+nlay;
                   1628:   }
                   1629:   return m; 
                   1630:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1631:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1632:   */
                   1633: }
                   1634: 
                   1635: /*************************free ma3x ************************/
                   1636: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1637: {
                   1638:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1639:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1640:   free((FREE_ARG)(m+nrl-NR_END));
                   1641: }
                   1642: 
                   1643: /*************** function subdirf ***********/
                   1644: char *subdirf(char fileres[])
                   1645: {
                   1646:   /* Caution optionfilefiname is hidden */
                   1647:   strcpy(tmpout,optionfilefiname);
                   1648:   strcat(tmpout,"/"); /* Add to the right */
                   1649:   strcat(tmpout,fileres);
                   1650:   return tmpout;
                   1651: }
                   1652: 
                   1653: /*************** function subdirf2 ***********/
                   1654: char *subdirf2(char fileres[], char *preop)
                   1655: {
                   1656:   
                   1657:   /* Caution optionfilefiname is hidden */
                   1658:   strcpy(tmpout,optionfilefiname);
                   1659:   strcat(tmpout,"/");
                   1660:   strcat(tmpout,preop);
                   1661:   strcat(tmpout,fileres);
                   1662:   return tmpout;
                   1663: }
                   1664: 
                   1665: /*************** function subdirf3 ***********/
                   1666: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1667: {
                   1668:   
                   1669:   /* Caution optionfilefiname is hidden */
                   1670:   strcpy(tmpout,optionfilefiname);
                   1671:   strcat(tmpout,"/");
                   1672:   strcat(tmpout,preop);
                   1673:   strcat(tmpout,preop2);
                   1674:   strcat(tmpout,fileres);
                   1675:   return tmpout;
                   1676: }
1.213     brouard  1677:  
                   1678: /*************** function subdirfext ***********/
                   1679: char *subdirfext(char fileres[], char *preop, char *postop)
                   1680: {
                   1681:   
                   1682:   strcpy(tmpout,preop);
                   1683:   strcat(tmpout,fileres);
                   1684:   strcat(tmpout,postop);
                   1685:   return tmpout;
                   1686: }
1.126     brouard  1687: 
1.213     brouard  1688: /*************** function subdirfext3 ***********/
                   1689: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1690: {
                   1691:   
                   1692:   /* Caution optionfilefiname is hidden */
                   1693:   strcpy(tmpout,optionfilefiname);
                   1694:   strcat(tmpout,"/");
                   1695:   strcat(tmpout,preop);
                   1696:   strcat(tmpout,fileres);
                   1697:   strcat(tmpout,postop);
                   1698:   return tmpout;
                   1699: }
                   1700:  
1.162     brouard  1701: char *asc_diff_time(long time_sec, char ascdiff[])
                   1702: {
                   1703:   long sec_left, days, hours, minutes;
                   1704:   days = (time_sec) / (60*60*24);
                   1705:   sec_left = (time_sec) % (60*60*24);
                   1706:   hours = (sec_left) / (60*60) ;
                   1707:   sec_left = (sec_left) %(60*60);
                   1708:   minutes = (sec_left) /60;
                   1709:   sec_left = (sec_left) % (60);
                   1710:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1711:   return ascdiff;
                   1712: }
                   1713: 
1.126     brouard  1714: /***************** f1dim *************************/
                   1715: extern int ncom; 
                   1716: extern double *pcom,*xicom;
                   1717: extern double (*nrfunc)(double []); 
                   1718:  
                   1719: double f1dim(double x) 
                   1720: { 
                   1721:   int j; 
                   1722:   double f;
                   1723:   double *xt; 
                   1724:  
                   1725:   xt=vector(1,ncom); 
                   1726:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1727:   f=(*nrfunc)(xt); 
                   1728:   free_vector(xt,1,ncom); 
                   1729:   return f; 
                   1730: } 
                   1731: 
                   1732: /*****************brent *************************/
                   1733: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1734: {
                   1735:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1736:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1737:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1738:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1739:    * returned function value. 
                   1740:   */
1.126     brouard  1741:   int iter; 
                   1742:   double a,b,d,etemp;
1.159     brouard  1743:   double fu=0,fv,fw,fx;
1.164     brouard  1744:   double ftemp=0.;
1.126     brouard  1745:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1746:   double e=0.0; 
                   1747:  
                   1748:   a=(ax < cx ? ax : cx); 
                   1749:   b=(ax > cx ? ax : cx); 
                   1750:   x=w=v=bx; 
                   1751:   fw=fv=fx=(*f)(x); 
                   1752:   for (iter=1;iter<=ITMAX;iter++) { 
                   1753:     xm=0.5*(a+b); 
                   1754:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1755:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1756:     printf(".");fflush(stdout);
                   1757:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1758: #ifdef DEBUGBRENT
1.126     brouard  1759:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1760:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1761:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1762: #endif
                   1763:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1764:       *xmin=x; 
                   1765:       return fx; 
                   1766:     } 
                   1767:     ftemp=fu;
                   1768:     if (fabs(e) > tol1) { 
                   1769:       r=(x-w)*(fx-fv); 
                   1770:       q=(x-v)*(fx-fw); 
                   1771:       p=(x-v)*q-(x-w)*r; 
                   1772:       q=2.0*(q-r); 
                   1773:       if (q > 0.0) p = -p; 
                   1774:       q=fabs(q); 
                   1775:       etemp=e; 
                   1776:       e=d; 
                   1777:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1778:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1779:       else { 
1.224     brouard  1780:                                d=p/q; 
                   1781:                                u=x+d; 
                   1782:                                if (u-a < tol2 || b-u < tol2) 
                   1783:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1784:       } 
                   1785:     } else { 
                   1786:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1787:     } 
                   1788:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1789:     fu=(*f)(u); 
                   1790:     if (fu <= fx) { 
                   1791:       if (u >= x) a=x; else b=x; 
                   1792:       SHFT(v,w,x,u) 
1.183     brouard  1793:       SHFT(fv,fw,fx,fu) 
                   1794:     } else { 
                   1795:       if (u < x) a=u; else b=u; 
                   1796:       if (fu <= fw || w == x) { 
1.224     brouard  1797:                                v=w; 
                   1798:                                w=u; 
                   1799:                                fv=fw; 
                   1800:                                fw=fu; 
1.183     brouard  1801:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1802:                                v=u; 
                   1803:                                fv=fu; 
1.183     brouard  1804:       } 
                   1805:     } 
1.126     brouard  1806:   } 
                   1807:   nrerror("Too many iterations in brent"); 
                   1808:   *xmin=x; 
                   1809:   return fx; 
                   1810: } 
                   1811: 
                   1812: /****************** mnbrak ***********************/
                   1813: 
                   1814: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1815:            double (*func)(double)) 
1.183     brouard  1816: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1817: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1818: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1819: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1820:    */
1.126     brouard  1821:   double ulim,u,r,q, dum;
                   1822:   double fu; 
1.187     brouard  1823: 
                   1824:   double scale=10.;
                   1825:   int iterscale=0;
                   1826: 
                   1827:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1828:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1829: 
                   1830: 
                   1831:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1832:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1833:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1834:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1835:   /* } */
                   1836: 
1.126     brouard  1837:   if (*fb > *fa) { 
                   1838:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1839:     SHFT(dum,*fb,*fa,dum) 
                   1840:   } 
1.126     brouard  1841:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1842:   *fc=(*func)(*cx); 
1.183     brouard  1843: #ifdef DEBUG
1.224     brouard  1844:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1845:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1846: #endif
1.224     brouard  1847:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1848:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1849:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1850:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1851:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1852:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1853:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1854:       fu=(*func)(u); 
1.163     brouard  1855: #ifdef DEBUG
                   1856:       /* f(x)=A(x-u)**2+f(u) */
                   1857:       double A, fparabu; 
                   1858:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1859:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1860:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1861:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1862:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1863:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1864:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1865:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1866: #endif 
1.184     brouard  1867: #ifdef MNBRAKORIGINAL
1.183     brouard  1868: #else
1.191     brouard  1869: /*       if (fu > *fc) { */
                   1870: /* #ifdef DEBUG */
                   1871: /*       printf("mnbrak4  fu > fc \n"); */
                   1872: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1873: /* #endif */
                   1874: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1875: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1876: /*     dum=u; /\* Shifting c and u *\/ */
                   1877: /*     u = *cx; */
                   1878: /*     *cx = dum; */
                   1879: /*     dum = fu; */
                   1880: /*     fu = *fc; */
                   1881: /*     *fc =dum; */
                   1882: /*       } else { /\* end *\/ */
                   1883: /* #ifdef DEBUG */
                   1884: /*       printf("mnbrak3  fu < fc \n"); */
                   1885: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1886: /* #endif */
                   1887: /*     dum=u; /\* Shifting c and u *\/ */
                   1888: /*     u = *cx; */
                   1889: /*     *cx = dum; */
                   1890: /*     dum = fu; */
                   1891: /*     fu = *fc; */
                   1892: /*     *fc =dum; */
                   1893: /*       } */
1.224     brouard  1894: #ifdef DEBUGMNBRAK
                   1895:                 double A, fparabu; 
                   1896:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1897:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1898:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1899:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1900: #endif
1.191     brouard  1901:       dum=u; /* Shifting c and u */
                   1902:       u = *cx;
                   1903:       *cx = dum;
                   1904:       dum = fu;
                   1905:       fu = *fc;
                   1906:       *fc =dum;
1.183     brouard  1907: #endif
1.162     brouard  1908:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1909: #ifdef DEBUG
1.224     brouard  1910:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1911:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1912: #endif
1.126     brouard  1913:       fu=(*func)(u); 
                   1914:       if (fu < *fc) { 
1.183     brouard  1915: #ifdef DEBUG
1.224     brouard  1916:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1917:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1918: #endif
                   1919:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1920:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1921: #ifdef DEBUG
                   1922:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1923: #endif
                   1924:       } 
1.162     brouard  1925:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1926: #ifdef DEBUG
1.224     brouard  1927:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1928:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1929: #endif
1.126     brouard  1930:       u=ulim; 
                   1931:       fu=(*func)(u); 
1.183     brouard  1932:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1933: #ifdef DEBUG
1.224     brouard  1934:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1935:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1936: #endif
1.126     brouard  1937:       u=(*cx)+GOLD*(*cx-*bx); 
                   1938:       fu=(*func)(u); 
1.224     brouard  1939: #ifdef DEBUG
                   1940:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1941:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1942: #endif
1.183     brouard  1943:     } /* end tests */
1.126     brouard  1944:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  1945:     SHFT(*fa,*fb,*fc,fu) 
                   1946: #ifdef DEBUG
1.224     brouard  1947:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   1948:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  1949: #endif
                   1950:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  1951: } 
                   1952: 
                   1953: /*************** linmin ************************/
1.162     brouard  1954: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   1955: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   1956: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   1957: the value of func at the returned location p . This is actually all accomplished by calling the
                   1958: routines mnbrak and brent .*/
1.126     brouard  1959: int ncom; 
                   1960: double *pcom,*xicom;
                   1961: double (*nrfunc)(double []); 
                   1962:  
1.224     brouard  1963: #ifdef LINMINORIGINAL
1.126     brouard  1964: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  1965: #else
                   1966: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   1967: #endif
1.126     brouard  1968: { 
                   1969:   double brent(double ax, double bx, double cx, 
                   1970:               double (*f)(double), double tol, double *xmin); 
                   1971:   double f1dim(double x); 
                   1972:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   1973:              double *fc, double (*func)(double)); 
                   1974:   int j; 
                   1975:   double xx,xmin,bx,ax; 
                   1976:   double fx,fb,fa;
1.187     brouard  1977: 
1.203     brouard  1978: #ifdef LINMINORIGINAL
                   1979: #else
                   1980:   double scale=10., axs, xxs; /* Scale added for infinity */
                   1981: #endif
                   1982:   
1.126     brouard  1983:   ncom=n; 
                   1984:   pcom=vector(1,n); 
                   1985:   xicom=vector(1,n); 
                   1986:   nrfunc=func; 
                   1987:   for (j=1;j<=n;j++) { 
                   1988:     pcom[j]=p[j]; 
1.202     brouard  1989:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  1990:   } 
1.187     brouard  1991: 
1.203     brouard  1992: #ifdef LINMINORIGINAL
                   1993:   xx=1.;
                   1994: #else
                   1995:   axs=0.0;
                   1996:   xxs=1.;
                   1997:   do{
                   1998:     xx= xxs;
                   1999: #endif
1.187     brouard  2000:     ax=0.;
                   2001:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2002:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2003:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2004:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2005:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2006:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2007:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2008: #ifdef LINMINORIGINAL
                   2009: #else
                   2010:     if (fx != fx){
1.224     brouard  2011:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2012:                        printf("|");
                   2013:                        fprintf(ficlog,"|");
1.203     brouard  2014: #ifdef DEBUGLINMIN
1.224     brouard  2015:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2016: #endif
                   2017:     }
1.224     brouard  2018:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2019: #endif
                   2020:   
1.191     brouard  2021: #ifdef DEBUGLINMIN
                   2022:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2023:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2024: #endif
1.224     brouard  2025: #ifdef LINMINORIGINAL
                   2026: #else
                   2027:        if(fb == fx){ /* Flat function in the direction */
                   2028:                xmin=xx;
                   2029:     *flat=1;
                   2030:        }else{
                   2031:     *flat=0;
                   2032: #endif
                   2033:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2034:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2035:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2036:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2037:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2038:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2039: #ifdef DEBUG
1.224     brouard  2040:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2041:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2042: #endif
                   2043: #ifdef LINMINORIGINAL
                   2044: #else
                   2045:                        }
1.126     brouard  2046: #endif
1.191     brouard  2047: #ifdef DEBUGLINMIN
                   2048:   printf("linmin end ");
1.202     brouard  2049:   fprintf(ficlog,"linmin end ");
1.191     brouard  2050: #endif
1.126     brouard  2051:   for (j=1;j<=n;j++) { 
1.203     brouard  2052: #ifdef LINMINORIGINAL
                   2053:     xi[j] *= xmin; 
                   2054: #else
                   2055: #ifdef DEBUGLINMIN
                   2056:     if(xxs <1.0)
                   2057:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2058: #endif
                   2059:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2060: #ifdef DEBUGLINMIN
                   2061:     if(xxs <1.0)
                   2062:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2063: #endif
                   2064: #endif
1.187     brouard  2065:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2066:   } 
1.191     brouard  2067: #ifdef DEBUGLINMIN
1.203     brouard  2068:   printf("\n");
1.191     brouard  2069:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2070:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2071:   for (j=1;j<=n;j++) { 
1.202     brouard  2072:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2073:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2074:     if(j % ncovmodel == 0){
1.191     brouard  2075:       printf("\n");
1.202     brouard  2076:       fprintf(ficlog,"\n");
                   2077:     }
1.191     brouard  2078:   }
1.203     brouard  2079: #else
1.191     brouard  2080: #endif
1.126     brouard  2081:   free_vector(xicom,1,n); 
                   2082:   free_vector(pcom,1,n); 
                   2083: } 
                   2084: 
                   2085: 
                   2086: /*************** powell ************************/
1.162     brouard  2087: /*
                   2088: Minimization of a function func of n variables. Input consists of an initial starting point
                   2089: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2090: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2091: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2092: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2093: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2094:  */
1.224     brouard  2095: #ifdef LINMINORIGINAL
                   2096: #else
                   2097:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2098:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2099: #endif
1.126     brouard  2100: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2101:            double (*func)(double [])) 
                   2102: { 
1.224     brouard  2103: #ifdef LINMINORIGINAL
                   2104:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2105:              double (*func)(double [])); 
1.224     brouard  2106: #else 
1.241     brouard  2107:  void linmin(double p[], double xi[], int n, double *fret,
                   2108:             double (*func)(double []),int *flat); 
1.224     brouard  2109: #endif
1.239     brouard  2110:  int i,ibig,j,jk,k; 
1.126     brouard  2111:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2112:   double directest;
1.126     brouard  2113:   double fp,fptt;
                   2114:   double *xits;
                   2115:   int niterf, itmp;
1.224     brouard  2116: #ifdef LINMINORIGINAL
                   2117: #else
                   2118: 
                   2119:   flatdir=ivector(1,n); 
                   2120:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2121: #endif
1.126     brouard  2122: 
                   2123:   pt=vector(1,n); 
                   2124:   ptt=vector(1,n); 
                   2125:   xit=vector(1,n); 
                   2126:   xits=vector(1,n); 
                   2127:   *fret=(*func)(p); 
                   2128:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2129:   rcurr_time = time(NULL);  
1.126     brouard  2130:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2131:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2132:     ibig=0; 
                   2133:     del=0.0; 
1.157     brouard  2134:     rlast_time=rcurr_time;
                   2135:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2136:     rcurr_time = time(NULL);  
                   2137:     curr_time = *localtime(&rcurr_time);
                   2138:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2139:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2140: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2141:     for (i=1;i<=n;i++) {
1.126     brouard  2142:       fprintf(ficrespow," %.12lf", p[i]);
                   2143:     }
1.239     brouard  2144:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2145:     printf("\n#model=  1      +     age ");
                   2146:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2147:     if(nagesqr==1){
1.241     brouard  2148:        printf("  + age*age  ");
                   2149:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2150:     }
                   2151:     for(j=1;j <=ncovmodel-2;j++){
                   2152:       if(Typevar[j]==0) {
                   2153:        printf("  +      V%d  ",Tvar[j]);
                   2154:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2155:       }else if(Typevar[j]==1) {
                   2156:        printf("  +    V%d*age ",Tvar[j]);
                   2157:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2158:       }else if(Typevar[j]==2) {
                   2159:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2160:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2161:       }
                   2162:     }
1.126     brouard  2163:     printf("\n");
1.239     brouard  2164: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2165: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2166:     fprintf(ficlog,"\n");
1.239     brouard  2167:     for(i=1,jk=1; i <=nlstate; i++){
                   2168:       for(k=1; k <=(nlstate+ndeath); k++){
                   2169:        if (k != i) {
                   2170:          printf("%d%d ",i,k);
                   2171:          fprintf(ficlog,"%d%d ",i,k);
                   2172:          for(j=1; j <=ncovmodel; j++){
                   2173:            printf("%12.7f ",p[jk]);
                   2174:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2175:            jk++; 
                   2176:          }
                   2177:          printf("\n");
                   2178:          fprintf(ficlog,"\n");
                   2179:        }
                   2180:       }
                   2181:     }
1.241     brouard  2182:     if(*iter <=3 && *iter >1){
1.157     brouard  2183:       tml = *localtime(&rcurr_time);
                   2184:       strcpy(strcurr,asctime(&tml));
                   2185:       rforecast_time=rcurr_time; 
1.126     brouard  2186:       itmp = strlen(strcurr);
                   2187:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2188:        strcurr[itmp-1]='\0';
1.162     brouard  2189:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2190:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2191:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2192:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2193:        forecast_time = *localtime(&rforecast_time);
                   2194:        strcpy(strfor,asctime(&forecast_time));
                   2195:        itmp = strlen(strfor);
                   2196:        if(strfor[itmp-1]=='\n')
                   2197:          strfor[itmp-1]='\0';
                   2198:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2199:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2200:       }
                   2201:     }
1.187     brouard  2202:     for (i=1;i<=n;i++) { /* For each direction i */
                   2203:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2204:       fptt=(*fret); 
                   2205: #ifdef DEBUG
1.203     brouard  2206:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2207:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2208: #endif
1.203     brouard  2209:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2210:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2211: #ifdef LINMINORIGINAL
1.188     brouard  2212:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2213: #else
                   2214:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2215:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2216: #endif
                   2217:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2218:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2219:                                /* because that direction will be replaced unless the gain del is small */
                   2220:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2221:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2222:                                /* with the new direction. */
                   2223:                                del=fabs(fptt-(*fret)); 
                   2224:                                ibig=i; 
1.126     brouard  2225:       } 
                   2226: #ifdef DEBUG
                   2227:       printf("%d %.12e",i,(*fret));
                   2228:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2229:       for (j=1;j<=n;j++) {
1.224     brouard  2230:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2231:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2232:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2233:       }
                   2234:       for(j=1;j<=n;j++) {
1.225     brouard  2235:                                printf(" p(%d)=%.12e",j,p[j]);
                   2236:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2237:       }
                   2238:       printf("\n");
                   2239:       fprintf(ficlog,"\n");
                   2240: #endif
1.187     brouard  2241:     } /* end loop on each direction i */
                   2242:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2243:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2244:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2245:       for(j=1;j<=n;j++) {
1.225     brouard  2246:                                if(flatdir[j] >0){
                   2247:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2248:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2249:                                }
                   2250:                                /* printf("\n"); */
                   2251:                                /* fprintf(ficlog,"\n"); */
                   2252:                        }
1.243     brouard  2253:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2254:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2255:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2256:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2257:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2258:       /* decreased of more than 3.84  */
                   2259:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2260:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2261:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2262:                        
1.188     brouard  2263:       /* Starting the program with initial values given by a former maximization will simply change */
                   2264:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2265:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2266:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2267: #ifdef DEBUG
                   2268:       int k[2],l;
                   2269:       k[0]=1;
                   2270:       k[1]=-1;
                   2271:       printf("Max: %.12e",(*func)(p));
                   2272:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2273:       for (j=1;j<=n;j++) {
                   2274:        printf(" %.12e",p[j]);
                   2275:        fprintf(ficlog," %.12e",p[j]);
                   2276:       }
                   2277:       printf("\n");
                   2278:       fprintf(ficlog,"\n");
                   2279:       for(l=0;l<=1;l++) {
                   2280:        for (j=1;j<=n;j++) {
                   2281:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2282:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2283:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2284:        }
                   2285:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2286:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2287:       }
                   2288: #endif
                   2289: 
1.224     brouard  2290: #ifdef LINMINORIGINAL
                   2291: #else
                   2292:       free_ivector(flatdir,1,n); 
                   2293: #endif
1.126     brouard  2294:       free_vector(xit,1,n); 
                   2295:       free_vector(xits,1,n); 
                   2296:       free_vector(ptt,1,n); 
                   2297:       free_vector(pt,1,n); 
                   2298:       return; 
1.192     brouard  2299:     } /* enough precision */ 
1.240     brouard  2300:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2301:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2302:       ptt[j]=2.0*p[j]-pt[j]; 
                   2303:       xit[j]=p[j]-pt[j]; 
                   2304:       pt[j]=p[j]; 
                   2305:     } 
1.181     brouard  2306:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2307: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2308:                if (*iter <=4) {
1.225     brouard  2309: #else
                   2310: #endif
1.224     brouard  2311: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2312: #else
1.161     brouard  2313:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2314: #endif
1.162     brouard  2315:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2316:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2317:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2318:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2319:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2320:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2321:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2322:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2323:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2324:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2325:       /* mu² and del² are equal when f3=f1 */
                   2326:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2327:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2328:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2329:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2330: #ifdef NRCORIGINAL
                   2331:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2332: #else
                   2333:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2334:       t= t- del*SQR(fp-fptt);
1.183     brouard  2335: #endif
1.202     brouard  2336:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2337: #ifdef DEBUG
1.181     brouard  2338:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2339:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2340:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2341:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2342:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2343:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2344:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2345:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2346: #endif
1.183     brouard  2347: #ifdef POWELLORIGINAL
                   2348:       if (t < 0.0) { /* Then we use it for new direction */
                   2349: #else
1.182     brouard  2350:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2351:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2352:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2353:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2354:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2355:       } 
1.181     brouard  2356:       if (directest < 0.0) { /* Then we use it for new direction */
                   2357: #endif
1.191     brouard  2358: #ifdef DEBUGLINMIN
1.234     brouard  2359:        printf("Before linmin in direction P%d-P0\n",n);
                   2360:        for (j=1;j<=n;j++) {
                   2361:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2362:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2363:          if(j % ncovmodel == 0){
                   2364:            printf("\n");
                   2365:            fprintf(ficlog,"\n");
                   2366:          }
                   2367:        }
1.224     brouard  2368: #endif
                   2369: #ifdef LINMINORIGINAL
1.234     brouard  2370:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2371: #else
1.234     brouard  2372:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2373:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2374: #endif
1.234     brouard  2375:        
1.191     brouard  2376: #ifdef DEBUGLINMIN
1.234     brouard  2377:        for (j=1;j<=n;j++) { 
                   2378:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2379:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2380:          if(j % ncovmodel == 0){
                   2381:            printf("\n");
                   2382:            fprintf(ficlog,"\n");
                   2383:          }
                   2384:        }
1.224     brouard  2385: #endif
1.234     brouard  2386:        for (j=1;j<=n;j++) { 
                   2387:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2388:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2389:        }
1.224     brouard  2390: #ifdef LINMINORIGINAL
                   2391: #else
1.234     brouard  2392:        for (j=1, flatd=0;j<=n;j++) {
                   2393:          if(flatdir[j]>0)
                   2394:            flatd++;
                   2395:        }
                   2396:        if(flatd >0){
                   2397:          printf("%d flat directions\n",flatd);
                   2398:          fprintf(ficlog,"%d flat directions\n",flatd);
                   2399:          for (j=1;j<=n;j++) { 
                   2400:            if(flatdir[j]>0){
                   2401:              printf("%d ",j);
                   2402:              fprintf(ficlog,"%d ",j);
                   2403:            }
                   2404:          }
                   2405:          printf("\n");
                   2406:          fprintf(ficlog,"\n");
                   2407:        }
1.191     brouard  2408: #endif
1.234     brouard  2409:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2410:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2411:        
1.126     brouard  2412: #ifdef DEBUG
1.234     brouard  2413:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2414:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2415:        for(j=1;j<=n;j++){
                   2416:          printf(" %lf",xit[j]);
                   2417:          fprintf(ficlog," %lf",xit[j]);
                   2418:        }
                   2419:        printf("\n");
                   2420:        fprintf(ficlog,"\n");
1.126     brouard  2421: #endif
1.192     brouard  2422:       } /* end of t or directest negative */
1.224     brouard  2423: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2424: #else
1.234     brouard  2425:       } /* end if (fptt < fp)  */
1.192     brouard  2426: #endif
1.225     brouard  2427: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2428:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2429: #else
1.224     brouard  2430: #endif
1.234     brouard  2431:                } /* loop iteration */ 
1.126     brouard  2432: } 
1.234     brouard  2433:   
1.126     brouard  2434: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2435:   
1.235     brouard  2436:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2437:   {
1.235     brouard  2438:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2439:        (and selected quantitative values in nres)
                   2440:        by left multiplying the unit
1.234     brouard  2441:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2442:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2443:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2444:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2445:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2446:   /* Initial matrix pimij */
                   2447:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2448:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2449:   /*  0,                   0                  , 1} */
                   2450:   /*
                   2451:    * and after some iteration: */
                   2452:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2453:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2454:   /*  0,                   0                  , 1} */
                   2455:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2456:   /* {0.51571254859325999, 0.4842874514067399, */
                   2457:   /*  0.51326036147820708, 0.48673963852179264} */
                   2458:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2459:     
1.126     brouard  2460:   int i, ii,j,k;
1.209     brouard  2461:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2462:   /* double **matprod2(); */ /* test */
1.218     brouard  2463:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2464:   double **newm;
1.209     brouard  2465:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2466:   int ncvloop=0;
1.169     brouard  2467:   
1.209     brouard  2468:   min=vector(1,nlstate);
                   2469:   max=vector(1,nlstate);
                   2470:   meandiff=vector(1,nlstate);
                   2471: 
1.218     brouard  2472:        /* Starting with matrix unity */
1.126     brouard  2473:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2474:     for (j=1;j<=nlstate+ndeath;j++){
                   2475:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2476:     }
1.169     brouard  2477:   
                   2478:   cov[1]=1.;
                   2479:   
                   2480:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2481:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2482:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2483:     ncvloop++;
1.126     brouard  2484:     newm=savm;
                   2485:     /* Covariates have to be included here again */
1.138     brouard  2486:     cov[2]=agefin;
1.187     brouard  2487:     if(nagesqr==1)
                   2488:       cov[3]= agefin*agefin;;
1.234     brouard  2489:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2490:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2491:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2492:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2493:     }
                   2494:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2495:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2496:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2497:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2498:     }
1.237     brouard  2499:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2500:       if(Dummy[Tvar[Tage[k]]]){
                   2501:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2502:       } else{
1.235     brouard  2503:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2504:       }
1.235     brouard  2505:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2506:     }
1.237     brouard  2507:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2508:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2509:       if(Dummy[Tvard[k][1]==0]){
                   2510:        if(Dummy[Tvard[k][2]==0]){
                   2511:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2512:        }else{
                   2513:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2514:        }
                   2515:       }else{
                   2516:        if(Dummy[Tvard[k][2]==0]){
                   2517:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2518:        }else{
                   2519:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2520:        }
                   2521:       }
1.234     brouard  2522:     }
1.138     brouard  2523:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2524:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2525:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2526:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2527:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2528:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2529:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2530:     
1.126     brouard  2531:     savm=oldm;
                   2532:     oldm=newm;
1.209     brouard  2533: 
                   2534:     for(j=1; j<=nlstate; j++){
                   2535:       max[j]=0.;
                   2536:       min[j]=1.;
                   2537:     }
                   2538:     for(i=1;i<=nlstate;i++){
                   2539:       sumnew=0;
                   2540:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2541:       for(j=1; j<=nlstate; j++){ 
                   2542:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2543:        max[j]=FMAX(max[j],prlim[i][j]);
                   2544:        min[j]=FMIN(min[j],prlim[i][j]);
                   2545:       }
                   2546:     }
                   2547: 
1.126     brouard  2548:     maxmax=0.;
1.209     brouard  2549:     for(j=1; j<=nlstate; j++){
                   2550:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2551:       maxmax=FMAX(maxmax,meandiff[j]);
                   2552:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2553:     } /* j loop */
1.203     brouard  2554:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2555:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2556:     if(maxmax < ftolpl){
1.209     brouard  2557:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2558:       free_vector(min,1,nlstate);
                   2559:       free_vector(max,1,nlstate);
                   2560:       free_vector(meandiff,1,nlstate);
1.126     brouard  2561:       return prlim;
                   2562:     }
1.169     brouard  2563:   } /* age loop */
1.208     brouard  2564:     /* After some age loop it doesn't converge */
1.209     brouard  2565:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2566: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2567:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2568:   free_vector(min,1,nlstate);
                   2569:   free_vector(max,1,nlstate);
                   2570:   free_vector(meandiff,1,nlstate);
1.208     brouard  2571:   
1.169     brouard  2572:   return prlim; /* should not reach here */
1.126     brouard  2573: }
                   2574: 
1.217     brouard  2575: 
                   2576:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2577: 
1.218     brouard  2578:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2579:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2580:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2581: {
1.218     brouard  2582:   /* Computes the prevalence limit in each live state at age x and covariate ij by left multiplying the unit
1.217     brouard  2583:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2584:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2585:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2586:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2587:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2588:   /* Initial matrix pimij */
                   2589:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2590:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2591:   /*  0,                   0                  , 1} */
                   2592:   /*
                   2593:    * and after some iteration: */
                   2594:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2595:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2596:   /*  0,                   0                  , 1} */
                   2597:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2598:   /* {0.51571254859325999, 0.4842874514067399, */
                   2599:   /*  0.51326036147820708, 0.48673963852179264} */
                   2600:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2601: 
                   2602:   int i, ii,j,k;
1.247     brouard  2603:   int first=0;
1.217     brouard  2604:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2605:   /* double **matprod2(); */ /* test */
                   2606:   double **out, cov[NCOVMAX+1], **bmij();
                   2607:   double **newm;
1.218     brouard  2608:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2609:   double        **oldm, **savm;  /* for use */
                   2610: 
1.217     brouard  2611:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2612:   int ncvloop=0;
                   2613:   
                   2614:   min=vector(1,nlstate);
                   2615:   max=vector(1,nlstate);
                   2616:   meandiff=vector(1,nlstate);
                   2617: 
1.218     brouard  2618:        dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2619:        oldm=oldms; savm=savms;
                   2620: 
                   2621:        /* Starting with matrix unity */
                   2622:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   2623:                for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2624:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2625:     }
                   2626:   
                   2627:   cov[1]=1.;
                   2628:   
                   2629:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2630:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2631:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2632:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2633:     ncvloop++;
1.218     brouard  2634:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2635:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2636:     /* Covariates have to be included here again */
                   2637:     cov[2]=agefin;
                   2638:     if(nagesqr==1)
                   2639:       cov[3]= agefin*agefin;;
1.242     brouard  2640:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2641:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2642:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   2643:       /* printf("bprevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   2644:     }
                   2645:     /* for (k=1; k<=cptcovn;k++) { */
                   2646:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2647:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2648:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2649:     /* } */
                   2650:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2651:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2652:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2653:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2654:     }
                   2655:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2656:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2657:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2658:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2659:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2660:       if(Dummy[Tvar[Tage[k]]]){
                   2661:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2662:       } else{
                   2663:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2664:       }
                   2665:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2666:     }
                   2667:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2668:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2669:       if(Dummy[Tvard[k][1]==0]){
                   2670:        if(Dummy[Tvard[k][2]==0]){
                   2671:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2672:        }else{
                   2673:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2674:        }
                   2675:       }else{
                   2676:        if(Dummy[Tvard[k][2]==0]){
                   2677:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2678:        }else{
                   2679:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2680:        }
                   2681:       }
1.217     brouard  2682:     }
                   2683:     
                   2684:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2685:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2686:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2687:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2688:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2689:                /* ij should be linked to the correct index of cov */
                   2690:                /* age and covariate values ij are in 'cov', but we need to pass
                   2691:                 * ij for the observed prevalence at age and status and covariate
                   2692:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2693:                 */
                   2694:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2695:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2696:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.217     brouard  2697:     savm=oldm;
                   2698:     oldm=newm;
                   2699:     for(j=1; j<=nlstate; j++){
                   2700:       max[j]=0.;
                   2701:       min[j]=1.;
                   2702:     }
                   2703:     for(j=1; j<=nlstate; j++){ 
                   2704:       for(i=1;i<=nlstate;i++){
1.234     brouard  2705:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2706:        bprlim[i][j]= newm[i][j];
                   2707:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2708:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2709:       }
                   2710:     }
1.218     brouard  2711:                
1.217     brouard  2712:     maxmax=0.;
                   2713:     for(i=1; i<=nlstate; i++){
                   2714:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2715:       maxmax=FMAX(maxmax,meandiff[i]);
                   2716:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
                   2717:     } /* j loop */
                   2718:     *ncvyear= -( (int)age- (int)agefin);
1.218     brouard  2719:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear);*/
1.217     brouard  2720:     if(maxmax < ftolpl){
1.220     brouard  2721:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2722:       free_vector(min,1,nlstate);
                   2723:       free_vector(max,1,nlstate);
                   2724:       free_vector(meandiff,1,nlstate);
                   2725:       return bprlim;
                   2726:     }
                   2727:   } /* age loop */
                   2728:     /* After some age loop it doesn't converge */
1.247     brouard  2729:   if(first){
                   2730:     first=1;
                   2731:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2732: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2733:   }
                   2734:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2735: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2736:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2737:   free_vector(min,1,nlstate);
                   2738:   free_vector(max,1,nlstate);
                   2739:   free_vector(meandiff,1,nlstate);
                   2740:   
                   2741:   return bprlim; /* should not reach here */
                   2742: }
                   2743: 
1.126     brouard  2744: /*************** transition probabilities ***************/ 
                   2745: 
                   2746: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2747: {
1.138     brouard  2748:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2749:      computes the probability to be observed in state j being in state i by appying the
                   2750:      model to the ncovmodel covariates (including constant and age).
                   2751:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2752:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2753:      ncth covariate in the global vector x is given by the formula:
                   2754:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2755:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2756:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2757:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2758:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2759:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2760:   */
                   2761:   double s1, lnpijopii;
1.126     brouard  2762:   /*double t34;*/
1.164     brouard  2763:   int i,j, nc, ii, jj;
1.126     brouard  2764: 
1.223     brouard  2765:   for(i=1; i<= nlstate; i++){
                   2766:     for(j=1; j<i;j++){
                   2767:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2768:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2769:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2770:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2771:       }
                   2772:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2773:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2774:     }
                   2775:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2776:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2777:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2778:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2779:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2780:       }
                   2781:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2782:     }
                   2783:   }
1.218     brouard  2784:   
1.223     brouard  2785:   for(i=1; i<= nlstate; i++){
                   2786:     s1=0;
                   2787:     for(j=1; j<i; j++){
                   2788:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2789:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2790:     }
                   2791:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2792:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2793:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2794:     }
                   2795:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2796:     ps[i][i]=1./(s1+1.);
                   2797:     /* Computing other pijs */
                   2798:     for(j=1; j<i; j++)
                   2799:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2800:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2801:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2802:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2803:   } /* end i */
1.218     brouard  2804:   
1.223     brouard  2805:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2806:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2807:       ps[ii][jj]=0;
                   2808:       ps[ii][ii]=1;
                   2809:     }
                   2810:   }
1.218     brouard  2811:   
                   2812:   
1.223     brouard  2813:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2814:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2815:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2816:   /*   } */
                   2817:   /*   printf("\n "); */
                   2818:   /* } */
                   2819:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2820:   /*
                   2821:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2822:                goto end;*/
1.223     brouard  2823:   return ps;
1.126     brouard  2824: }
                   2825: 
1.218     brouard  2826: /*************** backward transition probabilities ***************/ 
                   2827: 
                   2828:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2829: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2830:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2831: {
1.222     brouard  2832:   /* Computes the backward probability at age agefin and covariate ij
                   2833:    * and returns in **ps as well as **bmij.
                   2834:    */
1.218     brouard  2835:   int i, ii, j,k;
1.222     brouard  2836:   
                   2837:   double **out, **pmij();
                   2838:   double sumnew=0.;
1.218     brouard  2839:   double agefin;
1.222     brouard  2840:   
                   2841:   double **dnewm, **dsavm, **doldm;
                   2842:   double **bbmij;
                   2843:   
1.218     brouard  2844:   doldm=ddoldms; /* global pointers */
1.222     brouard  2845:   dnewm=ddnewms;
                   2846:   dsavm=ddsavms;
                   2847:   
                   2848:   agefin=cov[2];
                   2849:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
                   2850:      the observed prevalence (with this covariate ij) */
                   2851:   dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate);
                   2852:   /* We do have the matrix Px in savm  and we need pij */
                   2853:   for (j=1;j<=nlstate+ndeath;j++){
                   2854:     sumnew=0.; /* w1 p11 + w2 p21 only on live states */
                   2855:     for (ii=1;ii<=nlstate;ii++){
                   2856:       sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij];
                   2857:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
                   2858:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2859:       if(sumnew >= 1.e-10){
                   2860:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
                   2861:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2862:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
                   2863:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2864:        /* }else */
                   2865:        doldm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2866:       }else{
1.242     brouard  2867:        ;
                   2868:        /* printf("ii=%d, i=%d, doldm=%lf dsavm=%lf, probs=%lf, sumnew=%lf,agefin=%d\n",ii,j,doldm[ii][j],dsavm[ii][j],prevacurrent[(int)agefin][ii][ij],sumnew, (int)agefin); */
1.222     brouard  2869:       }
                   2870:     } /*End ii */
                   2871:   } /* End j, At the end doldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2872:   /* left Product of this diag matrix by dsavm=Px (newm=dsavm*doldm) */
                   2873:   bbmij=matprod2(dnewm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, doldm); /* Bug Valgrind */
                   2874:   /* dsavm=doldm; /\* dsavm is now diag [1/(w_1p1i+w_2 p2i)] but can be overwritten*\/ */
                   2875:   /* doldm=dnewm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2876:   /* dnewm=dsavm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2877:   /* left Product of this matrix by diag matrix of prevalences (savm) */
                   2878:   for (j=1;j<=nlstate+ndeath;j++){
                   2879:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2880:       dsavm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij] : 0.0);
                   2881:     }
                   2882:   } /* End j, At the end oldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2883:   ps=matprod2(doldm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dnewm); /* Bug Valgrind */
                   2884:   /* newm or out is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
                   2885:   /* end bmij */
                   2886:   return ps; 
1.218     brouard  2887: }
1.217     brouard  2888: /*************** transition probabilities ***************/ 
                   2889: 
1.218     brouard  2890: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2891: {
                   2892:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2893:      computes the probability to be observed in state j being in state i by appying the
                   2894:      model to the ncovmodel covariates (including constant and age).
                   2895:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2896:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2897:      ncth covariate in the global vector x is given by the formula:
                   2898:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2899:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2900:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2901:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2902:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2903:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2904:   */
                   2905:   double s1, lnpijopii;
                   2906:   /*double t34;*/
                   2907:   int i,j, nc, ii, jj;
                   2908: 
1.234     brouard  2909:   for(i=1; i<= nlstate; i++){
                   2910:     for(j=1; j<i;j++){
                   2911:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2912:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2913:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2914:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2915:       }
                   2916:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2917:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2918:     }
                   2919:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2920:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2921:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2922:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2923:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2924:       }
                   2925:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2926:     }
                   2927:   }
                   2928:   
                   2929:   for(i=1; i<= nlstate; i++){
                   2930:     s1=0;
                   2931:     for(j=1; j<i; j++){
                   2932:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2933:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2934:     }
                   2935:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2936:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2937:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2938:     }
                   2939:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2940:     ps[i][i]=1./(s1+1.);
                   2941:     /* Computing other pijs */
                   2942:     for(j=1; j<i; j++)
                   2943:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2944:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2945:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2946:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2947:   } /* end i */
                   2948:   
                   2949:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2950:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2951:       ps[ii][jj]=0;
                   2952:       ps[ii][ii]=1;
                   2953:     }
                   2954:   }
                   2955:   /* Added for backcast */ /* Transposed matrix too */
                   2956:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2957:     s1=0.;
                   2958:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   2959:       s1+=ps[ii][jj];
                   2960:     }
                   2961:     for(ii=1; ii<= nlstate; ii++){
                   2962:       ps[ii][jj]=ps[ii][jj]/s1;
                   2963:     }
                   2964:   }
                   2965:   /* Transposition */
                   2966:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2967:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   2968:       s1=ps[ii][jj];
                   2969:       ps[ii][jj]=ps[jj][ii];
                   2970:       ps[jj][ii]=s1;
                   2971:     }
                   2972:   }
                   2973:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2974:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2975:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2976:   /*   } */
                   2977:   /*   printf("\n "); */
                   2978:   /* } */
                   2979:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2980:   /*
                   2981:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   2982:     goto end;*/
                   2983:   return ps;
1.217     brouard  2984: }
                   2985: 
                   2986: 
1.126     brouard  2987: /**************** Product of 2 matrices ******************/
                   2988: 
1.145     brouard  2989: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  2990: {
                   2991:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   2992:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   2993:   /* in, b, out are matrice of pointers which should have been initialized 
                   2994:      before: only the contents of out is modified. The function returns
                   2995:      a pointer to pointers identical to out */
1.145     brouard  2996:   int i, j, k;
1.126     brouard  2997:   for(i=nrl; i<= nrh; i++)
1.145     brouard  2998:     for(k=ncolol; k<=ncoloh; k++){
                   2999:       out[i][k]=0.;
                   3000:       for(j=ncl; j<=nch; j++)
                   3001:        out[i][k] +=in[i][j]*b[j][k];
                   3002:     }
1.126     brouard  3003:   return out;
                   3004: }
                   3005: 
                   3006: 
                   3007: /************* Higher Matrix Product ***************/
                   3008: 
1.235     brouard  3009: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3010: {
1.218     brouard  3011:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3012:      'nhstepm*hstepm*stepm' months (i.e. until
                   3013:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3014:      nhstepm*hstepm matrices. 
                   3015:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3016:      (typically every 2 years instead of every month which is too big 
                   3017:      for the memory).
                   3018:      Model is determined by parameters x and covariates have to be 
                   3019:      included manually here. 
                   3020: 
                   3021:      */
                   3022: 
                   3023:   int i, j, d, h, k;
1.131     brouard  3024:   double **out, cov[NCOVMAX+1];
1.126     brouard  3025:   double **newm;
1.187     brouard  3026:   double agexact;
1.214     brouard  3027:   double agebegin, ageend;
1.126     brouard  3028: 
                   3029:   /* Hstepm could be zero and should return the unit matrix */
                   3030:   for (i=1;i<=nlstate+ndeath;i++)
                   3031:     for (j=1;j<=nlstate+ndeath;j++){
                   3032:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3033:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3034:     }
                   3035:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3036:   for(h=1; h <=nhstepm; h++){
                   3037:     for(d=1; d <=hstepm; d++){
                   3038:       newm=savm;
                   3039:       /* Covariates have to be included here again */
                   3040:       cov[1]=1.;
1.214     brouard  3041:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3042:       cov[2]=agexact;
                   3043:       if(nagesqr==1)
1.227     brouard  3044:        cov[3]= agexact*agexact;
1.235     brouard  3045:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3046:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3047:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3048:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3049:       }
                   3050:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3051:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3052:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3053:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3054:       }
                   3055:       for (k=1; k<=cptcovage;k++){
                   3056:        if(Dummy[Tvar[Tage[k]]]){
                   3057:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3058:        } else{
                   3059:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3060:        }
                   3061:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3062:       }
                   3063:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3064:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3065:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3066:       }
                   3067:       /* for (k=1; k<=cptcovn;k++)  */
                   3068:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3069:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3070:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3071:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3072:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3073:       
                   3074:       
1.126     brouard  3075:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3076:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3077:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3078:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3079:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3080:       /* if((int)age == 70){ */
                   3081:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3082:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3083:       /*         printf("%d pmmij ",i); */
                   3084:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3085:       /*           printf("%f ",pmmij[i][j]); */
                   3086:       /*         } */
                   3087:       /*         printf(" oldm "); */
                   3088:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3089:       /*           printf("%f ",oldm[i][j]); */
                   3090:       /*         } */
                   3091:       /*         printf("\n"); */
                   3092:       /*       } */
                   3093:       /* } */
1.126     brouard  3094:       savm=oldm;
                   3095:       oldm=newm;
                   3096:     }
                   3097:     for(i=1; i<=nlstate+ndeath; i++)
                   3098:       for(j=1;j<=nlstate+ndeath;j++) {
1.218     brouard  3099:                                po[i][j][h]=newm[i][j];
                   3100:                                /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3101:       }
1.128     brouard  3102:     /*printf("h=%d ",h);*/
1.126     brouard  3103:   } /* end h */
1.218     brouard  3104:        /*     printf("\n H=%d \n",h); */
1.126     brouard  3105:   return po;
                   3106: }
                   3107: 
1.217     brouard  3108: /************* Higher Back Matrix Product ***************/
1.218     brouard  3109: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.222     brouard  3110: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij )
1.217     brouard  3111: {
1.218     brouard  3112:   /* Computes the transition matrix starting at age 'age' over
1.217     brouard  3113:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3114:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3115:      nhstepm*hstepm matrices.
                   3116:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3117:      (typically every 2 years instead of every month which is too big
1.217     brouard  3118:      for the memory).
1.218     brouard  3119:      Model is determined by parameters x and covariates have to be
                   3120:      included manually here.
1.217     brouard  3121: 
1.222     brouard  3122:   */
1.217     brouard  3123: 
                   3124:   int i, j, d, h, k;
                   3125:   double **out, cov[NCOVMAX+1];
                   3126:   double **newm;
                   3127:   double agexact;
                   3128:   double agebegin, ageend;
1.222     brouard  3129:   double **oldm, **savm;
1.217     brouard  3130: 
1.222     brouard  3131:   oldm=oldms;savm=savms;
1.217     brouard  3132:   /* Hstepm could be zero and should return the unit matrix */
                   3133:   for (i=1;i<=nlstate+ndeath;i++)
                   3134:     for (j=1;j<=nlstate+ndeath;j++){
                   3135:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3136:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3137:     }
                   3138:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3139:   for(h=1; h <=nhstepm; h++){
                   3140:     for(d=1; d <=hstepm; d++){
                   3141:       newm=savm;
                   3142:       /* Covariates have to be included here again */
                   3143:       cov[1]=1.;
                   3144:       agexact=age-((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
                   3145:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3146:       cov[2]=agexact;
                   3147:       if(nagesqr==1)
1.222     brouard  3148:        cov[3]= agexact*agexact;
1.218     brouard  3149:       for (k=1; k<=cptcovn;k++)
1.222     brouard  3150:        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   3151:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.217     brouard  3152:       for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
1.222     brouard  3153:        /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   3154:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3155:       /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
1.217     brouard  3156:       for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
1.222     brouard  3157:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3158:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
1.218     brouard  3159:                        
                   3160:                        
1.217     brouard  3161:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3162:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3163:       /* Careful transposed matrix */
1.222     brouard  3164:       /* age is in cov[2] */
1.218     brouard  3165:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3166:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3167:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3168:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3169:       /* if((int)age == 70){ */
                   3170:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3171:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3172:       /*         printf("%d pmmij ",i); */
                   3173:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3174:       /*           printf("%f ",pmmij[i][j]); */
                   3175:       /*         } */
                   3176:       /*         printf(" oldm "); */
                   3177:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3178:       /*           printf("%f ",oldm[i][j]); */
                   3179:       /*         } */
                   3180:       /*         printf("\n"); */
                   3181:       /*       } */
                   3182:       /* } */
                   3183:       savm=oldm;
                   3184:       oldm=newm;
                   3185:     }
                   3186:     for(i=1; i<=nlstate+ndeath; i++)
                   3187:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3188:        po[i][j][h]=newm[i][j];
                   3189:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.217     brouard  3190:       }
                   3191:     /*printf("h=%d ",h);*/
                   3192:   } /* end h */
1.222     brouard  3193:   /*     printf("\n H=%d \n",h); */
1.217     brouard  3194:   return po;
                   3195: }
                   3196: 
                   3197: 
1.162     brouard  3198: #ifdef NLOPT
                   3199:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3200:   double fret;
                   3201:   double *xt;
                   3202:   int j;
                   3203:   myfunc_data *d2 = (myfunc_data *) pd;
                   3204: /* xt = (p1-1); */
                   3205:   xt=vector(1,n); 
                   3206:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3207: 
                   3208:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3209:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3210:   printf("Function = %.12lf ",fret);
                   3211:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3212:   printf("\n");
                   3213:  free_vector(xt,1,n);
                   3214:   return fret;
                   3215: }
                   3216: #endif
1.126     brouard  3217: 
                   3218: /*************** log-likelihood *************/
                   3219: double func( double *x)
                   3220: {
1.226     brouard  3221:   int i, ii, j, k, mi, d, kk;
                   3222:   int ioffset=0;
                   3223:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3224:   double **out;
                   3225:   double lli; /* Individual log likelihood */
                   3226:   int s1, s2;
1.228     brouard  3227:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3228:   double bbh, survp;
                   3229:   long ipmx;
                   3230:   double agexact;
                   3231:   /*extern weight */
                   3232:   /* We are differentiating ll according to initial status */
                   3233:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3234:   /*for(i=1;i<imx;i++) 
                   3235:     printf(" %d\n",s[4][i]);
                   3236:   */
1.162     brouard  3237: 
1.226     brouard  3238:   ++countcallfunc;
1.162     brouard  3239: 
1.226     brouard  3240:   cov[1]=1.;
1.126     brouard  3241: 
1.226     brouard  3242:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3243:   ioffset=0;
1.226     brouard  3244:   if(mle==1){
                   3245:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3246:       /* Computes the values of the ncovmodel covariates of the model
                   3247:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3248:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3249:         to be observed in j being in i according to the model.
                   3250:       */
1.243     brouard  3251:       ioffset=2+nagesqr ;
1.233     brouard  3252:    /* Fixed */
1.234     brouard  3253:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3254:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3255:       }
1.226     brouard  3256:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3257:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3258:         has been calculated etc */
                   3259:       /* For an individual i, wav[i] gives the number of effective waves */
                   3260:       /* We compute the contribution to Likelihood of each effective transition
                   3261:         mw[mi][i] is real wave of the mi th effectve wave */
                   3262:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3263:         s2=s[mw[mi+1][i]][i];
                   3264:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3265:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3266:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3267:       */
                   3268:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3269:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3270:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3271:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3272:        }
                   3273:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3274:          for (j=1;j<=nlstate+ndeath;j++){
                   3275:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3276:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3277:          }
                   3278:        for(d=0; d<dh[mi][i]; d++){
                   3279:          newm=savm;
                   3280:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3281:          cov[2]=agexact;
                   3282:          if(nagesqr==1)
                   3283:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3284:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3285:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3286:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3287:          else
                   3288:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3289:          }
                   3290:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3291:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3292:          savm=oldm;
                   3293:          oldm=newm;
                   3294:        } /* end mult */
                   3295:        
                   3296:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3297:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3298:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3299:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3300:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3301:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3302:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3303:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3304:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3305:                                 * -stepm/2 to stepm/2 .
                   3306:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3307:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3308:                                 */
1.234     brouard  3309:        s1=s[mw[mi][i]][i];
                   3310:        s2=s[mw[mi+1][i]][i];
                   3311:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3312:        /* bias bh is positive if real duration
                   3313:         * is higher than the multiple of stepm and negative otherwise.
                   3314:         */
                   3315:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3316:        if( s2 > nlstate){ 
                   3317:          /* i.e. if s2 is a death state and if the date of death is known 
                   3318:             then the contribution to the likelihood is the probability to 
                   3319:             die between last step unit time and current  step unit time, 
                   3320:             which is also equal to probability to die before dh 
                   3321:             minus probability to die before dh-stepm . 
                   3322:             In version up to 0.92 likelihood was computed
                   3323:             as if date of death was unknown. Death was treated as any other
                   3324:             health state: the date of the interview describes the actual state
                   3325:             and not the date of a change in health state. The former idea was
                   3326:             to consider that at each interview the state was recorded
                   3327:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3328:             introduced the exact date of death then we should have modified
                   3329:             the contribution of an exact death to the likelihood. This new
                   3330:             contribution is smaller and very dependent of the step unit
                   3331:             stepm. It is no more the probability to die between last interview
                   3332:             and month of death but the probability to survive from last
                   3333:             interview up to one month before death multiplied by the
                   3334:             probability to die within a month. Thanks to Chris
                   3335:             Jackson for correcting this bug.  Former versions increased
                   3336:             mortality artificially. The bad side is that we add another loop
                   3337:             which slows down the processing. The difference can be up to 10%
                   3338:             lower mortality.
                   3339:          */
                   3340:          /* If, at the beginning of the maximization mostly, the
                   3341:             cumulative probability or probability to be dead is
                   3342:             constant (ie = 1) over time d, the difference is equal to
                   3343:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3344:             s1 at precedent wave, to be dead a month before current
                   3345:             wave is equal to probability, being at state s1 at
                   3346:             precedent wave, to be dead at mont of the current
                   3347:             wave. Then the observed probability (that this person died)
                   3348:             is null according to current estimated parameter. In fact,
                   3349:             it should be very low but not zero otherwise the log go to
                   3350:             infinity.
                   3351:          */
1.183     brouard  3352: /* #ifdef INFINITYORIGINAL */
                   3353: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3354: /* #else */
                   3355: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3356: /*         lli=log(mytinydouble); */
                   3357: /*       else */
                   3358: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3359: /* #endif */
1.226     brouard  3360:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3361:          
1.226     brouard  3362:        } else if  ( s2==-1 ) { /* alive */
                   3363:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3364:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3365:          /*survp += out[s1][j]; */
                   3366:          lli= log(survp);
                   3367:        }
                   3368:        else if  (s2==-4) { 
                   3369:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3370:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3371:          lli= log(survp); 
                   3372:        } 
                   3373:        else if  (s2==-5) { 
                   3374:          for (j=1,survp=0. ; j<=2; j++)  
                   3375:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3376:          lli= log(survp); 
                   3377:        } 
                   3378:        else{
                   3379:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3380:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3381:        } 
                   3382:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3383:        /*if(lli ==000.0)*/
                   3384:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3385:        ipmx +=1;
                   3386:        sw += weight[i];
                   3387:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3388:        /* if (lli < log(mytinydouble)){ */
                   3389:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3390:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3391:        /* } */
                   3392:       } /* end of wave */
                   3393:     } /* end of individual */
                   3394:   }  else if(mle==2){
                   3395:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3396:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3397:       for(mi=1; mi<= wav[i]-1; mi++){
                   3398:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3399:          for (j=1;j<=nlstate+ndeath;j++){
                   3400:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3401:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3402:          }
                   3403:        for(d=0; d<=dh[mi][i]; d++){
                   3404:          newm=savm;
                   3405:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3406:          cov[2]=agexact;
                   3407:          if(nagesqr==1)
                   3408:            cov[3]= agexact*agexact;
                   3409:          for (kk=1; kk<=cptcovage;kk++) {
                   3410:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3411:          }
                   3412:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3413:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3414:          savm=oldm;
                   3415:          oldm=newm;
                   3416:        } /* end mult */
                   3417:       
                   3418:        s1=s[mw[mi][i]][i];
                   3419:        s2=s[mw[mi+1][i]][i];
                   3420:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3421:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3422:        ipmx +=1;
                   3423:        sw += weight[i];
                   3424:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3425:       } /* end of wave */
                   3426:     } /* end of individual */
                   3427:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3428:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3429:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3430:       for(mi=1; mi<= wav[i]-1; mi++){
                   3431:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3432:          for (j=1;j<=nlstate+ndeath;j++){
                   3433:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3434:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3435:          }
                   3436:        for(d=0; d<dh[mi][i]; d++){
                   3437:          newm=savm;
                   3438:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3439:          cov[2]=agexact;
                   3440:          if(nagesqr==1)
                   3441:            cov[3]= agexact*agexact;
                   3442:          for (kk=1; kk<=cptcovage;kk++) {
                   3443:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3444:          }
                   3445:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3446:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3447:          savm=oldm;
                   3448:          oldm=newm;
                   3449:        } /* end mult */
                   3450:       
                   3451:        s1=s[mw[mi][i]][i];
                   3452:        s2=s[mw[mi+1][i]][i];
                   3453:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3454:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3455:        ipmx +=1;
                   3456:        sw += weight[i];
                   3457:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3458:       } /* end of wave */
                   3459:     } /* end of individual */
                   3460:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3461:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3462:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3463:       for(mi=1; mi<= wav[i]-1; mi++){
                   3464:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3465:          for (j=1;j<=nlstate+ndeath;j++){
                   3466:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3467:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3468:          }
                   3469:        for(d=0; d<dh[mi][i]; d++){
                   3470:          newm=savm;
                   3471:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3472:          cov[2]=agexact;
                   3473:          if(nagesqr==1)
                   3474:            cov[3]= agexact*agexact;
                   3475:          for (kk=1; kk<=cptcovage;kk++) {
                   3476:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3477:          }
1.126     brouard  3478:        
1.226     brouard  3479:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3480:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3481:          savm=oldm;
                   3482:          oldm=newm;
                   3483:        } /* end mult */
                   3484:       
                   3485:        s1=s[mw[mi][i]][i];
                   3486:        s2=s[mw[mi+1][i]][i];
                   3487:        if( s2 > nlstate){ 
                   3488:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3489:        } else if  ( s2==-1 ) { /* alive */
                   3490:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3491:            survp += out[s1][j];
                   3492:          lli= log(survp);
                   3493:        }else{
                   3494:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3495:        }
                   3496:        ipmx +=1;
                   3497:        sw += weight[i];
                   3498:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3499: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3500:       } /* end of wave */
                   3501:     } /* end of individual */
                   3502:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3503:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3504:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3505:       for(mi=1; mi<= wav[i]-1; mi++){
                   3506:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3507:          for (j=1;j<=nlstate+ndeath;j++){
                   3508:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3509:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3510:          }
                   3511:        for(d=0; d<dh[mi][i]; d++){
                   3512:          newm=savm;
                   3513:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3514:          cov[2]=agexact;
                   3515:          if(nagesqr==1)
                   3516:            cov[3]= agexact*agexact;
                   3517:          for (kk=1; kk<=cptcovage;kk++) {
                   3518:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3519:          }
1.126     brouard  3520:        
1.226     brouard  3521:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3522:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3523:          savm=oldm;
                   3524:          oldm=newm;
                   3525:        } /* end mult */
                   3526:       
                   3527:        s1=s[mw[mi][i]][i];
                   3528:        s2=s[mw[mi+1][i]][i];
                   3529:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3530:        ipmx +=1;
                   3531:        sw += weight[i];
                   3532:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3533:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3534:       } /* end of wave */
                   3535:     } /* end of individual */
                   3536:   } /* End of if */
                   3537:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3538:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3539:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3540:   return -l;
1.126     brouard  3541: }
                   3542: 
                   3543: /*************** log-likelihood *************/
                   3544: double funcone( double *x)
                   3545: {
1.228     brouard  3546:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3547:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3548:   int ioffset=0;
1.131     brouard  3549:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3550:   double **out;
                   3551:   double lli; /* Individual log likelihood */
                   3552:   double llt;
                   3553:   int s1, s2;
1.228     brouard  3554:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3555: 
1.126     brouard  3556:   double bbh, survp;
1.187     brouard  3557:   double agexact;
1.214     brouard  3558:   double agebegin, ageend;
1.126     brouard  3559:   /*extern weight */
                   3560:   /* We are differentiating ll according to initial status */
                   3561:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3562:   /*for(i=1;i<imx;i++) 
                   3563:     printf(" %d\n",s[4][i]);
                   3564:   */
                   3565:   cov[1]=1.;
                   3566: 
                   3567:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3568:   ioffset=0;
                   3569:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3570:     /* ioffset=2+nagesqr+cptcovage; */
                   3571:     ioffset=2+nagesqr;
1.232     brouard  3572:     /* Fixed */
1.224     brouard  3573:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3574:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3575:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3576:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3577: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3578: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3579: /*    cov[2+6]=covar[2][i]; V2  */
                   3580: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3581: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3582: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3583: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3584: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3585: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3586:     }
1.232     brouard  3587:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3588:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3589:     /* } */
1.231     brouard  3590:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3591:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3592:     /* } */
1.225     brouard  3593:     
1.233     brouard  3594: 
                   3595:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3596:     /* Wave varying (but not age varying) */
                   3597:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3598:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3599:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3600:       }
1.232     brouard  3601:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3602:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3603:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3604:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3605:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3606:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3607:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3608:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3609:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3610:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3611:       /* } */
1.126     brouard  3612:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3613:        for (j=1;j<=nlstate+ndeath;j++){
                   3614:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3615:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3616:        }
1.214     brouard  3617:       
                   3618:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3619:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3620:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3621:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3622:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3623:          and mw[mi+1][i]. dh depends on stepm.*/
                   3624:        newm=savm;
1.247     brouard  3625:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3626:        cov[2]=agexact;
                   3627:        if(nagesqr==1)
                   3628:          cov[3]= agexact*agexact;
                   3629:        for (kk=1; kk<=cptcovage;kk++) {
                   3630:          if(!FixedV[Tvar[Tage[kk]]])
                   3631:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3632:          else
                   3633:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3634:        }
                   3635:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3636:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3637:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3638:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3639:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3640:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3641:        savm=oldm;
                   3642:        oldm=newm;
1.126     brouard  3643:       } /* end mult */
                   3644:       
                   3645:       s1=s[mw[mi][i]][i];
                   3646:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3647:       /* if(s2==-1){ */
                   3648:       /*       printf(" s1=%d, s2=%d i=%d \n", s1, s2, i); */
                   3649:       /*       /\* exit(1); *\/ */
                   3650:       /* } */
1.126     brouard  3651:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3652:       /* bias is positive if real duration
                   3653:        * is higher than the multiple of stepm and negative otherwise.
                   3654:        */
                   3655:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3656:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3657:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3658:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3659:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3660:        lli= log(survp);
1.126     brouard  3661:       }else if (mle==1){
1.242     brouard  3662:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3663:       } else if(mle==2){
1.242     brouard  3664:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3665:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3666:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3667:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3668:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3669:       } else{  /* mle=0 back to 1 */
1.242     brouard  3670:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3671:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3672:       } /* End of if */
                   3673:       ipmx +=1;
                   3674:       sw += weight[i];
                   3675:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3676:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3677:       if(globpr){
1.246     brouard  3678:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3679:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3680:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
                   3681:                2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
                   3682:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3683:          llt +=ll[k]*gipmx/gsw;
                   3684:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3685:        }
                   3686:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3687:       }
1.232     brouard  3688:        } /* end of wave */
                   3689: } /* end of individual */
                   3690: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3691: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3692: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3693: if(globpr==0){ /* First time we count the contributions and weights */
                   3694:        gipmx=ipmx;
                   3695:        gsw=sw;
                   3696: }
                   3697: return -l;
1.126     brouard  3698: }
                   3699: 
                   3700: 
                   3701: /*************** function likelione ***********/
                   3702: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3703: {
                   3704:   /* This routine should help understanding what is done with 
                   3705:      the selection of individuals/waves and
                   3706:      to check the exact contribution to the likelihood.
                   3707:      Plotting could be done.
                   3708:    */
                   3709:   int k;
                   3710: 
                   3711:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3712:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3713:     strcat(fileresilk,fileresu);
1.126     brouard  3714:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3715:       printf("Problem with resultfile: %s\n", fileresilk);
                   3716:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3717:     }
1.214     brouard  3718:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3719:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3720:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3721:     for(k=1; k<=nlstate; k++) 
                   3722:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3723:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3724:   }
                   3725: 
                   3726:   *fretone=(*funcone)(p);
                   3727:   if(*globpri !=0){
                   3728:     fclose(ficresilk);
1.205     brouard  3729:     if (mle ==0)
                   3730:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3731:     else if(mle >=1)
                   3732:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3733:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3734:     
1.208     brouard  3735:       
                   3736:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3737:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3738: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3739:     }
1.207     brouard  3740:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3741: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3742:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3743: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3744:     fflush(fichtm);
1.205     brouard  3745:   }
1.126     brouard  3746:   return;
                   3747: }
                   3748: 
                   3749: 
                   3750: /*********** Maximum Likelihood Estimation ***************/
                   3751: 
                   3752: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3753: {
1.165     brouard  3754:   int i,j, iter=0;
1.126     brouard  3755:   double **xi;
                   3756:   double fret;
                   3757:   double fretone; /* Only one call to likelihood */
                   3758:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3759: 
                   3760: #ifdef NLOPT
                   3761:   int creturn;
                   3762:   nlopt_opt opt;
                   3763:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3764:   double *lb;
                   3765:   double minf; /* the minimum objective value, upon return */
                   3766:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3767:   myfunc_data dinst, *d = &dinst;
                   3768: #endif
                   3769: 
                   3770: 
1.126     brouard  3771:   xi=matrix(1,npar,1,npar);
                   3772:   for (i=1;i<=npar;i++)
                   3773:     for (j=1;j<=npar;j++)
                   3774:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3775:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3776:   strcpy(filerespow,"POW_"); 
1.126     brouard  3777:   strcat(filerespow,fileres);
                   3778:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3779:     printf("Problem with resultfile: %s\n", filerespow);
                   3780:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3781:   }
                   3782:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3783:   for (i=1;i<=nlstate;i++)
                   3784:     for(j=1;j<=nlstate+ndeath;j++)
                   3785:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3786:   fprintf(ficrespow,"\n");
1.162     brouard  3787: #ifdef POWELL
1.126     brouard  3788:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3789: #endif
1.126     brouard  3790: 
1.162     brouard  3791: #ifdef NLOPT
                   3792: #ifdef NEWUOA
                   3793:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3794: #else
                   3795:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3796: #endif
                   3797:   lb=vector(0,npar-1);
                   3798:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3799:   nlopt_set_lower_bounds(opt, lb);
                   3800:   nlopt_set_initial_step1(opt, 0.1);
                   3801:   
                   3802:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3803:   d->function = func;
                   3804:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3805:   nlopt_set_min_objective(opt, myfunc, d);
                   3806:   nlopt_set_xtol_rel(opt, ftol);
                   3807:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3808:     printf("nlopt failed! %d\n",creturn); 
                   3809:   }
                   3810:   else {
                   3811:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3812:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3813:     iter=1; /* not equal */
                   3814:   }
                   3815:   nlopt_destroy(opt);
                   3816: #endif
1.126     brouard  3817:   free_matrix(xi,1,npar,1,npar);
                   3818:   fclose(ficrespow);
1.203     brouard  3819:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3820:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3821:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3822: 
                   3823: }
                   3824: 
                   3825: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3826: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3827: {
                   3828:   double  **a,**y,*x,pd;
1.203     brouard  3829:   /* double **hess; */
1.164     brouard  3830:   int i, j;
1.126     brouard  3831:   int *indx;
                   3832: 
                   3833:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3834:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3835:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3836:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3837:   double gompertz(double p[]);
1.203     brouard  3838:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3839: 
                   3840:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3841:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3842:   for (i=1;i<=npar;i++){
1.203     brouard  3843:     printf("%d-",i);fflush(stdout);
                   3844:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3845:    
                   3846:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3847:     
                   3848:     /*  printf(" %f ",p[i]);
                   3849:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3850:   }
                   3851:   
                   3852:   for (i=1;i<=npar;i++) {
                   3853:     for (j=1;j<=npar;j++)  {
                   3854:       if (j>i) { 
1.203     brouard  3855:        printf(".%d-%d",i,j);fflush(stdout);
                   3856:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3857:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3858:        
                   3859:        hess[j][i]=hess[i][j];    
                   3860:        /*printf(" %lf ",hess[i][j]);*/
                   3861:       }
                   3862:     }
                   3863:   }
                   3864:   printf("\n");
                   3865:   fprintf(ficlog,"\n");
                   3866: 
                   3867:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3868:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3869:   
                   3870:   a=matrix(1,npar,1,npar);
                   3871:   y=matrix(1,npar,1,npar);
                   3872:   x=vector(1,npar);
                   3873:   indx=ivector(1,npar);
                   3874:   for (i=1;i<=npar;i++)
                   3875:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3876:   ludcmp(a,npar,indx,&pd);
                   3877: 
                   3878:   for (j=1;j<=npar;j++) {
                   3879:     for (i=1;i<=npar;i++) x[i]=0;
                   3880:     x[j]=1;
                   3881:     lubksb(a,npar,indx,x);
                   3882:     for (i=1;i<=npar;i++){ 
                   3883:       matcov[i][j]=x[i];
                   3884:     }
                   3885:   }
                   3886: 
                   3887:   printf("\n#Hessian matrix#\n");
                   3888:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   3889:   for (i=1;i<=npar;i++) { 
                   3890:     for (j=1;j<=npar;j++) { 
1.203     brouard  3891:       printf("%.6e ",hess[i][j]);
                   3892:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  3893:     }
                   3894:     printf("\n");
                   3895:     fprintf(ficlog,"\n");
                   3896:   }
                   3897: 
1.203     brouard  3898:   /* printf("\n#Covariance matrix#\n"); */
                   3899:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   3900:   /* for (i=1;i<=npar;i++) {  */
                   3901:   /*   for (j=1;j<=npar;j++) {  */
                   3902:   /*     printf("%.6e ",matcov[i][j]); */
                   3903:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   3904:   /*   } */
                   3905:   /*   printf("\n"); */
                   3906:   /*   fprintf(ficlog,"\n"); */
                   3907:   /* } */
                   3908: 
1.126     brouard  3909:   /* Recompute Inverse */
1.203     brouard  3910:   /* for (i=1;i<=npar;i++) */
                   3911:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   3912:   /* ludcmp(a,npar,indx,&pd); */
                   3913: 
                   3914:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   3915: 
                   3916:   /* for (j=1;j<=npar;j++) { */
                   3917:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   3918:   /*   x[j]=1; */
                   3919:   /*   lubksb(a,npar,indx,x); */
                   3920:   /*   for (i=1;i<=npar;i++){  */
                   3921:   /*     y[i][j]=x[i]; */
                   3922:   /*     printf("%.3e ",y[i][j]); */
                   3923:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   3924:   /*   } */
                   3925:   /*   printf("\n"); */
                   3926:   /*   fprintf(ficlog,"\n"); */
                   3927:   /* } */
                   3928: 
                   3929:   /* Verifying the inverse matrix */
                   3930: #ifdef DEBUGHESS
                   3931:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  3932: 
1.203     brouard  3933:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   3934:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  3935: 
                   3936:   for (j=1;j<=npar;j++) {
                   3937:     for (i=1;i<=npar;i++){ 
1.203     brouard  3938:       printf("%.2f ",y[i][j]);
                   3939:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  3940:     }
                   3941:     printf("\n");
                   3942:     fprintf(ficlog,"\n");
                   3943:   }
1.203     brouard  3944: #endif
1.126     brouard  3945: 
                   3946:   free_matrix(a,1,npar,1,npar);
                   3947:   free_matrix(y,1,npar,1,npar);
                   3948:   free_vector(x,1,npar);
                   3949:   free_ivector(indx,1,npar);
1.203     brouard  3950:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  3951: 
                   3952: 
                   3953: }
                   3954: 
                   3955: /*************** hessian matrix ****************/
                   3956: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  3957: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  3958:   int i;
                   3959:   int l=1, lmax=20;
1.203     brouard  3960:   double k1,k2, res, fx;
1.132     brouard  3961:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  3962:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   3963:   int k=0,kmax=10;
                   3964:   double l1;
                   3965: 
                   3966:   fx=func(x);
                   3967:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  3968:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  3969:     l1=pow(10,l);
                   3970:     delts=delt;
                   3971:     for(k=1 ; k <kmax; k=k+1){
                   3972:       delt = delta*(l1*k);
                   3973:       p2[theta]=x[theta] +delt;
1.145     brouard  3974:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  3975:       p2[theta]=x[theta]-delt;
                   3976:       k2=func(p2)-fx;
                   3977:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  3978:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  3979:       
1.203     brouard  3980: #ifdef DEBUGHESSII
1.126     brouard  3981:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3982:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3983: #endif
                   3984:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   3985:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   3986:        k=kmax;
                   3987:       }
                   3988:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  3989:        k=kmax; l=lmax*10;
1.126     brouard  3990:       }
                   3991:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   3992:        delts=delt;
                   3993:       }
1.203     brouard  3994:     } /* End loop k */
1.126     brouard  3995:   }
                   3996:   delti[theta]=delts;
                   3997:   return res; 
                   3998:   
                   3999: }
                   4000: 
1.203     brouard  4001: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4002: {
                   4003:   int i;
1.164     brouard  4004:   int l=1, lmax=20;
1.126     brouard  4005:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4006:   double p2[MAXPARM+1];
1.203     brouard  4007:   int k, kmax=1;
                   4008:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4009: 
                   4010:   int firstime=0;
1.203     brouard  4011:   
1.126     brouard  4012:   fx=func(x);
1.203     brouard  4013:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4014:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4015:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4016:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4017:     k1=func(p2)-fx;
                   4018:   
1.203     brouard  4019:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4020:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4021:     k2=func(p2)-fx;
                   4022:   
1.203     brouard  4023:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4024:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4025:     k3=func(p2)-fx;
                   4026:   
1.203     brouard  4027:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4028:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4029:     k4=func(p2)-fx;
1.203     brouard  4030:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4031:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4032:       firstime=1;
1.203     brouard  4033:       kmax=kmax+10;
1.208     brouard  4034:     }
                   4035:     if(kmax >=10 || firstime ==1){
1.246     brouard  4036:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4037:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4038:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4039:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4040:     }
                   4041: #ifdef DEBUGHESSIJ
                   4042:     v1=hess[thetai][thetai];
                   4043:     v2=hess[thetaj][thetaj];
                   4044:     cv12=res;
                   4045:     /* Computing eigen value of Hessian matrix */
                   4046:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4047:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4048:     if ((lc2 <0) || (lc1 <0) ){
                   4049:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4050:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4051:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4052:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4053:     }
1.126     brouard  4054: #endif
                   4055:   }
                   4056:   return res;
                   4057: }
                   4058: 
1.203     brouard  4059:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4060: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4061: /* { */
                   4062: /*   int i; */
                   4063: /*   int l=1, lmax=20; */
                   4064: /*   double k1,k2,k3,k4,res,fx; */
                   4065: /*   double p2[MAXPARM+1]; */
                   4066: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4067: /*   int k=0,kmax=10; */
                   4068: /*   double l1; */
                   4069:   
                   4070: /*   fx=func(x); */
                   4071: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4072: /*     l1=pow(10,l); */
                   4073: /*     delts=delt; */
                   4074: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4075: /*       delt = delti*(l1*k); */
                   4076: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4077: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4078: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4079: /*       k1=func(p2)-fx; */
                   4080:       
                   4081: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4082: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4083: /*       k2=func(p2)-fx; */
                   4084:       
                   4085: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4086: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4087: /*       k3=func(p2)-fx; */
                   4088:       
                   4089: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4090: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4091: /*       k4=func(p2)-fx; */
                   4092: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4093: /* #ifdef DEBUGHESSIJ */
                   4094: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4095: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4096: /* #endif */
                   4097: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4098: /*     k=kmax; */
                   4099: /*       } */
                   4100: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4101: /*     k=kmax; l=lmax*10; */
                   4102: /*       } */
                   4103: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4104: /*     delts=delt; */
                   4105: /*       } */
                   4106: /*     } /\* End loop k *\/ */
                   4107: /*   } */
                   4108: /*   delti[theta]=delts; */
                   4109: /*   return res;  */
                   4110: /* } */
                   4111: 
                   4112: 
1.126     brouard  4113: /************** Inverse of matrix **************/
                   4114: void ludcmp(double **a, int n, int *indx, double *d) 
                   4115: { 
                   4116:   int i,imax,j,k; 
                   4117:   double big,dum,sum,temp; 
                   4118:   double *vv; 
                   4119:  
                   4120:   vv=vector(1,n); 
                   4121:   *d=1.0; 
                   4122:   for (i=1;i<=n;i++) { 
                   4123:     big=0.0; 
                   4124:     for (j=1;j<=n;j++) 
                   4125:       if ((temp=fabs(a[i][j])) > big) big=temp; 
                   4126:     if (big == 0.0) nrerror("Singular matrix in routine ludcmp"); 
                   4127:     vv[i]=1.0/big; 
                   4128:   } 
                   4129:   for (j=1;j<=n;j++) { 
                   4130:     for (i=1;i<j;i++) { 
                   4131:       sum=a[i][j]; 
                   4132:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4133:       a[i][j]=sum; 
                   4134:     } 
                   4135:     big=0.0; 
                   4136:     for (i=j;i<=n;i++) { 
                   4137:       sum=a[i][j]; 
                   4138:       for (k=1;k<j;k++) 
                   4139:        sum -= a[i][k]*a[k][j]; 
                   4140:       a[i][j]=sum; 
                   4141:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4142:        big=dum; 
                   4143:        imax=i; 
                   4144:       } 
                   4145:     } 
                   4146:     if (j != imax) { 
                   4147:       for (k=1;k<=n;k++) { 
                   4148:        dum=a[imax][k]; 
                   4149:        a[imax][k]=a[j][k]; 
                   4150:        a[j][k]=dum; 
                   4151:       } 
                   4152:       *d = -(*d); 
                   4153:       vv[imax]=vv[j]; 
                   4154:     } 
                   4155:     indx[j]=imax; 
                   4156:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4157:     if (j != n) { 
                   4158:       dum=1.0/(a[j][j]); 
                   4159:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4160:     } 
                   4161:   } 
                   4162:   free_vector(vv,1,n);  /* Doesn't work */
                   4163: ;
                   4164: } 
                   4165: 
                   4166: void lubksb(double **a, int n, int *indx, double b[]) 
                   4167: { 
                   4168:   int i,ii=0,ip,j; 
                   4169:   double sum; 
                   4170:  
                   4171:   for (i=1;i<=n;i++) { 
                   4172:     ip=indx[i]; 
                   4173:     sum=b[ip]; 
                   4174:     b[ip]=b[i]; 
                   4175:     if (ii) 
                   4176:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4177:     else if (sum) ii=i; 
                   4178:     b[i]=sum; 
                   4179:   } 
                   4180:   for (i=n;i>=1;i--) { 
                   4181:     sum=b[i]; 
                   4182:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4183:     b[i]=sum/a[i][i]; 
                   4184:   } 
                   4185: } 
                   4186: 
                   4187: void pstamp(FILE *fichier)
                   4188: {
1.196     brouard  4189:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4190: }
                   4191: 
1.253   ! brouard  4192: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
        !          4193: 
        !          4194:   /* y=a+bx regression */
        !          4195:   double   sumx = 0.0;                        /* sum of x                      */
        !          4196:   double   sumx2 = 0.0;                       /* sum of x**2                   */
        !          4197:   double   sumxy = 0.0;                       /* sum of x * y                  */
        !          4198:   double   sumy = 0.0;                        /* sum of y                      */
        !          4199:   double   sumy2 = 0.0;                       /* sum of y**2                   */
        !          4200:   double   sume2; /* sum of square or residuals */
        !          4201:   double yhat;
        !          4202:   
        !          4203:   double denom=0;
        !          4204:   int i;
        !          4205:   int ne=*no;
        !          4206:   
        !          4207:   for ( i=ifi, ne=0;i<=ila;i++) {
        !          4208:     if(!isfinite(x[i]) || !isfinite(y[i])){
        !          4209:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
        !          4210:       continue;
        !          4211:     }
        !          4212:     ne=ne+1;
        !          4213:     sumx  += x[i];       
        !          4214:     sumx2 += x[i]*x[i];  
        !          4215:     sumxy += x[i] * y[i];
        !          4216:     sumy  += y[i];      
        !          4217:     sumy2 += y[i]*y[i]; 
        !          4218:     denom = (ne * sumx2 - sumx*sumx);
        !          4219:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
        !          4220:   } 
        !          4221:   
        !          4222:   denom = (ne * sumx2 - sumx*sumx);
        !          4223:   if (denom == 0) {
        !          4224:     // vertical, slope m is infinity
        !          4225:     *b = INFINITY;
        !          4226:     *a = 0;
        !          4227:     if (r) *r = 0;
        !          4228:     return 1;
        !          4229:   }
        !          4230:   
        !          4231:   *b = (ne * sumxy  -  sumx * sumy) / denom;
        !          4232:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
        !          4233:   if (r!=NULL) {
        !          4234:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
        !          4235:       sqrt((sumx2 - sumx*sumx/ne) *
        !          4236:           (sumy2 - sumy*sumy/ne));
        !          4237:   }
        !          4238:   *no=ne;
        !          4239:   for ( i=ifi, ne=0;i<=ila;i++) {
        !          4240:     if(!isfinite(x[i]) || !isfinite(y[i])){
        !          4241:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
        !          4242:       continue;
        !          4243:     }
        !          4244:     ne=ne+1;
        !          4245:     yhat = y[i] - *a -*b* x[i];
        !          4246:     sume2  += yhat * yhat ;       
        !          4247:     
        !          4248:     denom = (ne * sumx2 - sumx*sumx);
        !          4249:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
        !          4250:   } 
        !          4251:   *sb = sqrt(sume2/(ne-2)/(sumx2 - sumx * sumx /ne));
        !          4252:   *sa= *sb * sqrt(sumx2/ne);
        !          4253:   
        !          4254:   return 0; 
        !          4255: }
        !          4256: 
1.126     brouard  4257: /************ Frequencies ********************/
1.251     brouard  4258: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4259:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4260:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4261: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4262:   
1.253   ! brouard  4263:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0;
1.226     brouard  4264:   int iind=0, iage=0;
                   4265:   int mi; /* Effective wave */
                   4266:   int first;
                   4267:   double ***freq; /* Frequencies */
1.253   ! brouard  4268:   double *x, *y, a,b,r, sa, sb; /* for regression, y=b+m*x and r is the correlation coefficient */
        !          4269:   int no;
1.226     brouard  4270:   double *meanq;
                   4271:   double **meanqt;
                   4272:   double *pp, **prop, *posprop, *pospropt;
                   4273:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4274:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4275:   double agebegin, ageend;
                   4276:     
                   4277:   pp=vector(1,nlstate);
1.251     brouard  4278:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4279:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4280:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4281:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4282:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4283:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4284:   strcpy(fileresp,"P_");
                   4285:   strcat(fileresp,fileresu);
                   4286:   /*strcat(fileresphtm,fileresu);*/
                   4287:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4288:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4289:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4290:     exit(0);
                   4291:   }
1.240     brouard  4292:   
1.226     brouard  4293:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4294:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4295:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4296:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4297:     fflush(ficlog);
                   4298:     exit(70); 
                   4299:   }
                   4300:   else{
                   4301:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4302: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4303: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4304:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4305:   }
1.237     brouard  4306:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4307:   
1.226     brouard  4308:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4309:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4310:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4311:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4312:     fflush(ficlog);
                   4313:     exit(70); 
1.240     brouard  4314:   } else{
1.226     brouard  4315:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4316: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4317: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4318:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4319:   }
1.240     brouard  4320:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4321:   
1.253   ! brouard  4322:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
        !          4323:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4324:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4325:   j1=0;
1.126     brouard  4326:   
1.227     brouard  4327:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4328:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4329:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4330:   
                   4331:   
1.226     brouard  4332:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4333:      reference=low_education V1=0,V2=0
                   4334:      med_educ                V1=1 V2=0, 
                   4335:      high_educ               V1=0 V2=1
                   4336:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4337:   */
1.249     brouard  4338:   dateintsum=0;
                   4339:   k2cpt=0;
                   4340: 
1.253   ! brouard  4341:   if(cptcoveff == 0 )
        !          4342:     nl=1;  /* Constant model only */
        !          4343:   else
        !          4344:     nl=2;
        !          4345:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
        !          4346:     if(nj==1)
        !          4347:       j=0;  /* First pass for the constant */
        !          4348:     else
        !          4349:       j=cptcoveff; /* Other passes for the covariate values */
1.251     brouard  4350:     first=1;
                   4351:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on covariates combination in order of model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
                   4352:       posproptt=0.;
                   4353:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4354:        scanf("%d", i);*/
                   4355:       for (i=-5; i<=nlstate+ndeath; i++)  
                   4356:        for (jk=-5; jk<=nlstate+ndeath; jk++)  
                   4357:          for(m=iagemin; m <= iagemax+3; m++)
                   4358:            freq[i][jk][m]=0;
                   4359:       
                   4360:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4361:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4362:          prop[i][m]=0;
                   4363:        posprop[i]=0;
                   4364:        pospropt[i]=0;
                   4365:       }
                   4366:       /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4367:       /*   meanq[z1]+=0.; */
                   4368:       /*   for(m=1;m<=lastpass;m++){ */
                   4369:       /*       meanqt[m][z1]=0.; */
                   4370:       /*   } */
                   4371:       /* } */
                   4372:       
                   4373:       /* dateintsum=0; */
                   4374:       /* k2cpt=0; */
                   4375:       
                   4376:       /* For that combination of covariate j1, we count and print the frequencies in one pass */
                   4377:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4378:        bool=1;
                   4379:        if(j !=0){
                   4380:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4381:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4382:              /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4383:              /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4384:              /* } */
                   4385:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4386:                /* if(Tvaraff[z1] ==-20){ */
                   4387:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4388:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4389:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4390:                /* }else  */
                   4391:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
                   4392:                  /* Tests if this individual iind responded to combination j1 (V4=1 V3=0) */
                   4393:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4394:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4395:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4396:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4397:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4398:                } /* Onlyf fixed */
                   4399:              } /* end z1 */
                   4400:            } /* cptcovn > 0 */
                   4401:          } /* end any */
                   4402:        }/* end j==0 */
                   4403:        if (bool==1){ /* We selected an individual iind satisfying combination j1 or all fixed */
                   4404:          /* for(m=firstpass; m<=lastpass; m++){ */
                   4405:          for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4406:            m=mw[mi][iind];
                   4407:            if(j!=0){
                   4408:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4409:                for (z1=1; z1<=cptcoveff; z1++) {
                   4410:                  if( Fixed[Tmodelind[z1]]==1){
                   4411:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4412:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4413:                                                                                      value is -1, we don't select. It differs from the 
                   4414:                                                                                      constant and age model which counts them. */
                   4415:                      bool=0; /* not selected */
                   4416:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4417:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4418:                      bool=0;
                   4419:                    }
                   4420:                  }
                   4421:                }
                   4422:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4423:            } /* end j==0 */
                   4424:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4425:            if(bool==1){
                   4426:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4427:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4428:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4429:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4430:              if(m >=firstpass && m <=lastpass){
                   4431:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4432:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4433:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4434:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4435:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4436:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4437:                if (m<lastpass) {
                   4438:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4439:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4440:                  if(s[m][iind]==-1)
                   4441:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4442:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4443:                  /* if((int)agev[m][iind] == 55) */
                   4444:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4445:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4446:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4447:                }
1.251     brouard  4448:              } /* end if between passes */  
                   4449:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4450:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4451:                k2cpt++;
                   4452:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4453:              }
1.251     brouard  4454:            }else{
                   4455:              bool=1;
                   4456:            }/* end bool 2 */
                   4457:          } /* end m */
                   4458:        } /* end bool */
                   4459:       } /* end iind = 1 to imx */
                   4460:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4461:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4462:       
                   4463:       
                   4464:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
                   4465:       pstamp(ficresp);
                   4466:       if  (cptcoveff>0 && j!=0){
                   4467:        printf( "\n#********** Variable "); 
                   4468:        fprintf(ficresp, "\n#********** Variable "); 
                   4469:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4470:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4471:        fprintf(ficlog, "\n#********** Variable "); 
                   4472:        for (z1=1; z1<=cptcoveff; z1++){
                   4473:          if(!FixedV[Tvaraff[z1]]){
                   4474:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4475:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4476:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4477:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4478:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4479:          }else{
1.251     brouard  4480:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4481:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4482:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4483:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4484:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4485:          }
                   4486:        }
                   4487:        printf( "**********\n#");
                   4488:        fprintf(ficresp, "**********\n#");
                   4489:        fprintf(ficresphtm, "**********</h3>\n");
                   4490:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4491:        fprintf(ficlog, "**********\n");
                   4492:       }
                   4493:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
                   4494:       for(i=1; i<=nlstate;i++) {
                   4495:        fprintf(ficresp, " Age Prev(%d)  N(%d)  N  ",i,i);
                   4496:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4497:       }
                   4498:       fprintf(ficresp, "\n");
                   4499:       fprintf(ficresphtm, "\n");
                   4500:       
                   4501:       /* Header of frequency table by age */
                   4502:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4503:       fprintf(ficresphtmfr,"<th>Age</th> ");
                   4504:       for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4505:        for(m=-1; m <=nlstate+ndeath; m++){
                   4506:          if(jk!=0 && m!=0)
                   4507:            fprintf(ficresphtmfr,"<th>%d%d</th> ",jk,m);
1.240     brouard  4508:        }
1.226     brouard  4509:       }
1.251     brouard  4510:       fprintf(ficresphtmfr, "\n");
                   4511:     
                   4512:       /* For each age */
                   4513:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4514:        fprintf(ficresphtm,"<tr>");
                   4515:        if(iage==iagemax+1){
                   4516:          fprintf(ficlog,"1");
                   4517:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4518:        }else if(iage==iagemax+2){
                   4519:          fprintf(ficlog,"0");
                   4520:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4521:        }else if(iage==iagemax+3){
                   4522:          fprintf(ficlog,"Total");
                   4523:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4524:        }else{
1.240     brouard  4525:          if(first==1){
1.251     brouard  4526:            first=0;
                   4527:            printf("See log file for details...\n");
                   4528:          }
                   4529:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4530:          fprintf(ficlog,"Age %d", iage);
                   4531:        }
                   4532:        for(jk=1; jk <=nlstate ; jk++){
                   4533:          for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
                   4534:            pp[jk] += freq[jk][m][iage]; 
                   4535:        }
                   4536:        for(jk=1; jk <=nlstate ; jk++){
                   4537:          for(m=-1, pos=0; m <=0 ; m++)
                   4538:            pos += freq[jk][m][iage];
                   4539:          if(pp[jk]>=1.e-10){
                   4540:            if(first==1){
                   4541:              printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4542:            }
                   4543:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4544:          }else{
                   4545:            if(first==1)
                   4546:              printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
                   4547:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
1.240     brouard  4548:          }
                   4549:        }
                   4550:       
1.251     brouard  4551:        for(jk=1; jk <=nlstate ; jk++){ 
                   4552:          /* posprop[jk]=0; */
                   4553:          for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4554:            pp[jk] += freq[jk][m][iage];
                   4555:        }       /* pp[jk] is the total number of transitions starting from state jk and any ending status until this age */
                   4556:       
                   4557:        for(jk=1,pos=0, pospropta=0.; jk <=nlstate ; jk++){
                   4558:          pos += pp[jk]; /* pos is the total number of transitions until this age */
                   4559:          posprop[jk] += prop[jk][iage]; /* prop is the number of transitions from a live state
                   4560:                                            from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4561:          pospropta += prop[jk][iage]; /* prop is the number of transitions from a live state
1.240     brouard  4562:                                          from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4563:        }
1.251     brouard  4564:        for(jk=1; jk <=nlstate ; jk++){
1.240     brouard  4565:          if(pos>=1.e-5){
1.251     brouard  4566:            if(first==1)
                   4567:              printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4568:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4569:          }else{
                   4570:            if(first==1)
                   4571:              printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4572:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4573:          }
                   4574:          if( iage <= iagemax){
                   4575:            if(pos>=1.e-5){
                   4576:              fprintf(ficresp," %d %.5f %.0f %.0f",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4577:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4578:              /*probs[iage][jk][j1]= pp[jk]/pos;*/
                   4579:              /*printf("\niage=%d jk=%d j1=%d %.5f %.0f %.0f %f",iage,jk,j1,pp[jk]/pos, pp[jk],pos,probs[iage][jk][j1]);*/
                   4580:            }
                   4581:            else{
                   4582:              fprintf(ficresp," %d NaNq %.0f %.0f",iage,prop[jk][iage],pospropta);
                   4583:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[jk][iage],pospropta);
                   4584:            }
1.240     brouard  4585:          }
1.251     brouard  4586:          pospropt[jk] +=posprop[jk];
                   4587:        } /* end loop jk */
                   4588:        /* pospropt=0.; */
                   4589:        for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4590:          for(m=-1; m <=nlstate+ndeath; m++){
                   4591:            if(freq[jk][m][iage] !=0 ) { /* minimizing output */
                   4592:              if(first==1){
                   4593:                printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4594:              }
1.253   ! brouard  4595:              /* printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]); */
1.251     brouard  4596:              fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4597:            }
                   4598:            if(jk!=0 && m!=0)
                   4599:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[jk][m][iage]);
1.240     brouard  4600:          }
1.251     brouard  4601:        } /* end loop jk */
                   4602:        posproptt=0.; 
                   4603:        for(jk=1; jk <=nlstate; jk++){
                   4604:          posproptt += pospropt[jk];
                   4605:        }
                   4606:        fprintf(ficresphtmfr,"</tr>\n ");
                   4607:        if(iage <= iagemax){
                   4608:          fprintf(ficresp,"\n");
                   4609:          fprintf(ficresphtm,"</tr>\n");
1.240     brouard  4610:        }
1.251     brouard  4611:        if(first==1)
                   4612:          printf("Others in log...\n");
                   4613:        fprintf(ficlog,"\n");
                   4614:       } /* end loop age iage */
                   4615:       fprintf(ficresphtm,"<tr><th>Tot</th>");
                   4616:       for(jk=1; jk <=nlstate ; jk++){
                   4617:        if(posproptt < 1.e-5){
                   4618:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[jk],posproptt); 
                   4619:        }else{
                   4620:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[jk]/posproptt,pospropt[jk],posproptt);  
1.240     brouard  4621:        }
1.226     brouard  4622:       }
1.251     brouard  4623:       fprintf(ficresphtm,"</tr>\n");
                   4624:       fprintf(ficresphtm,"</table>\n");
                   4625:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4626:       if(posproptt < 1.e-5){
1.251     brouard  4627:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4628:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4629:        fprintf(ficres,"\n  This combination (%d) is not valid and no result will be produced\n\n",j1);
                   4630:        invalidvarcomb[j1]=1;
1.226     brouard  4631:       }else{
1.251     brouard  4632:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4633:        invalidvarcomb[j1]=0;
1.226     brouard  4634:       }
1.251     brouard  4635:       fprintf(ficresphtmfr,"</table>\n");
                   4636:       fprintf(ficlog,"\n");
                   4637:       if(j!=0){
                   4638:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
                   4639:        for(i=1,jk=1; i <=nlstate; i++){
                   4640:          for(k=1; k <=(nlstate+ndeath); k++){
                   4641:            if (k != i) {
                   4642:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting jk */
1.253   ! brouard  4643:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4644:                  if(j1==1){ /* All dummy covariates to zero */
                   4645:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4646:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4647:                    printf("%d%d ",i,k);
                   4648:                    fprintf(ficlog,"%d%d ",i,k);
                   4649:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4650:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4651:                    pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4652:                  }
1.253   ! brouard  4653:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
        !          4654:                  for(iage=iagemin; iage <= iagemax+3; iage++){
        !          4655:                    x[iage]= (double)iage;
        !          4656:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
        !          4657:                    /* printf("i=%d, k=%d, jk=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,jk,j1,jj, iage, y[iage]); */
        !          4658:                  }
        !          4659:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
        !          4660:                  pstart[jk]=b;
        !          4661:                  pstart[jk-1]=a;
1.252     brouard  4662:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4663:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4664:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.251     brouard  4665:                  pstart[jk]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4666:                  printf("%d%d ",i,k);
                   4667:                  fprintf(ficlog,"%d%d ",i,k);
1.251     brouard  4668:                  printf("jk=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",jk,i,k,jk,p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
                   4669:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4670:                  ;
                   4671:                }
                   4672:                /* printf("%12.7f )", param[i][jj][k]); */
                   4673:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
                   4674:                jk++; 
                   4675:              } /* end jj */
                   4676:            } /* end k!= i */
                   4677:          } /* end k */
                   4678:        } /* end i, jk */
                   4679:       } /* end j !=0 */
                   4680:     } /* end selected combination of covariate j1 */
                   4681:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4682:       printf("#Freqsummary: Starting values for the constants:\n");
                   4683:       fprintf(ficlog,"\n");
                   4684:       for(i=1,jk=1; i <=nlstate; i++){
                   4685:        for(k=1; k <=(nlstate+ndeath); k++){
                   4686:          if (k != i) {
                   4687:            printf("%d%d ",i,k);
                   4688:            fprintf(ficlog,"%d%d ",i,k);
                   4689:            for(jj=1; jj <=ncovmodel; jj++){
1.253   ! brouard  4690:              pstart[jk]=p[jk]; /* Setting pstart to p values by default */
        !          4691:              if(jj==1){ /* Age has to be done */
        !          4692:                pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4693:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4694:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4695:              }
                   4696:              /* printf("%12.7f )", param[i][jj][k]); */
                   4697:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
                   4698:              jk++; 
1.250     brouard  4699:            }
1.251     brouard  4700:            printf("\n");
                   4701:            fprintf(ficlog,"\n");
1.250     brouard  4702:          }
                   4703:        }
                   4704:       }
1.251     brouard  4705:       printf("#Freqsummary\n");
                   4706:       fprintf(ficlog,"\n");
                   4707:       for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4708:        for(m=-1; m <=nlstate+ndeath; m++){
                   4709:          /* param[i]|j][k]= freq[jk][m][iagemax+3] */
1.250     brouard  4710:          printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
                   4711:          fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
1.251     brouard  4712:          /* if(freq[jk][m][iage] !=0 ) { /\* minimizing output *\/ */
                   4713:          /*   printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
                   4714:          /*   fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
                   4715:          /* } */
                   4716:        }
                   4717:       } /* end loop jk */
                   4718:       
                   4719:       printf("\n");
                   4720:       fprintf(ficlog,"\n");
                   4721:     } /* end j=0 */
1.249     brouard  4722:   } /* end j */
1.252     brouard  4723: 
1.253   ! brouard  4724:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4725:     for(i=1, jk=1; i <=nlstate; i++){
                   4726:       for(j=1; j <=nlstate+ndeath; j++){
                   4727:        if(j!=i){
                   4728:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4729:          printf("%1d%1d",i,j);
                   4730:          fprintf(ficparo,"%1d%1d",i,j);
                   4731:          for(k=1; k<=ncovmodel;k++){
                   4732:            /*    printf(" %lf",param[i][j][k]); */
                   4733:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4734:            p[jk]=pstart[jk];
                   4735:            printf(" %f ",pstart[jk]);
                   4736:            fprintf(ficparo," %f ",pstart[jk]);
                   4737:            jk++;
                   4738:          }
                   4739:          printf("\n");
                   4740:          fprintf(ficparo,"\n");
                   4741:        }
                   4742:       }
                   4743:     }
                   4744:   } /* end mle=-2 */
1.226     brouard  4745:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4746:   
1.226     brouard  4747:   fclose(ficresp);
                   4748:   fclose(ficresphtm);
                   4749:   fclose(ficresphtmfr);
                   4750:   free_vector(meanq,1,nqfveff);
                   4751:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253   ! brouard  4752:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
        !          4753:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4754:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4755:   free_vector(pospropt,1,nlstate);
                   4756:   free_vector(posprop,1,nlstate);
1.251     brouard  4757:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4758:   free_vector(pp,1,nlstate);
                   4759:   /* End of freqsummary */
                   4760: }
1.126     brouard  4761: 
                   4762: /************ Prevalence ********************/
1.227     brouard  4763: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4764: {  
                   4765:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4766:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4767:      We still use firstpass and lastpass as another selection.
                   4768:   */
1.126     brouard  4769:  
1.227     brouard  4770:   int i, m, jk, j1, bool, z1,j, iv;
                   4771:   int mi; /* Effective wave */
                   4772:   int iage;
                   4773:   double agebegin, ageend;
                   4774: 
                   4775:   double **prop;
                   4776:   double posprop; 
                   4777:   double  y2; /* in fractional years */
                   4778:   int iagemin, iagemax;
                   4779:   int first; /** to stop verbosity which is redirected to log file */
                   4780: 
                   4781:   iagemin= (int) agemin;
                   4782:   iagemax= (int) agemax;
                   4783:   /*pp=vector(1,nlstate);*/
1.251     brouard  4784:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  4785:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4786:   j1=0;
1.222     brouard  4787:   
1.227     brouard  4788:   /*j=cptcoveff;*/
                   4789:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4790:   
1.227     brouard  4791:   first=1;
                   4792:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4793:     for (i=1; i<=nlstate; i++)  
1.251     brouard  4794:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  4795:        prop[i][iage]=0.0;
                   4796:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4797:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4798:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4799:     
                   4800:     for (i=1; i<=imx; i++) { /* Each individual */
                   4801:       bool=1;
                   4802:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4803:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4804:        m=mw[mi][i];
                   4805:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4806:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4807:        for (z1=1; z1<=cptcoveff; z1++){
                   4808:          if( Fixed[Tmodelind[z1]]==1){
                   4809:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4810:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4811:              bool=0;
                   4812:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4813:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4814:              bool=0;
                   4815:            }
                   4816:        }
                   4817:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4818:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4819:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4820:          if(m >=firstpass && m <=lastpass){
                   4821:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4822:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4823:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   4824:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  4825:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  4826:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   4827:                exit(1);
                   4828:              }
                   4829:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   4830:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   4831:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   4832:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   4833:              } /* end valid statuses */ 
                   4834:            } /* end selection of dates */
                   4835:          } /* end selection of waves */
                   4836:        } /* end bool */
                   4837:       } /* end wave */
                   4838:     } /* end individual */
                   4839:     for(i=iagemin; i <= iagemax+3; i++){  
                   4840:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   4841:        posprop += prop[jk][i]; 
                   4842:       } 
                   4843:       
                   4844:       for(jk=1; jk <=nlstate ; jk++){      
                   4845:        if( i <=  iagemax){ 
                   4846:          if(posprop>=1.e-5){ 
                   4847:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   4848:          } else{
                   4849:            if(first==1){
                   4850:              first=0;
                   4851:              printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,j1,probs[i][jk][j1]);
                   4852:            }
                   4853:          }
                   4854:        } 
                   4855:       }/* end jk */ 
                   4856:     }/* end i */ 
1.222     brouard  4857:      /*} *//* end i1 */
1.227     brouard  4858:   } /* end j1 */
1.222     brouard  4859:   
1.227     brouard  4860:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   4861:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  4862:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  4863: }  /* End of prevalence */
1.126     brouard  4864: 
                   4865: /************* Waves Concatenation ***************/
                   4866: 
                   4867: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   4868: {
                   4869:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   4870:      Death is a valid wave (if date is known).
                   4871:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   4872:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4873:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  4874:   */
1.126     brouard  4875: 
1.224     brouard  4876:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  4877:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   4878:      double sum=0., jmean=0.;*/
1.224     brouard  4879:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  4880:   int j, k=0,jk, ju, jl;
                   4881:   double sum=0.;
                   4882:   first=0;
1.214     brouard  4883:   firstwo=0;
1.217     brouard  4884:   firsthree=0;
1.218     brouard  4885:   firstfour=0;
1.164     brouard  4886:   jmin=100000;
1.126     brouard  4887:   jmax=-1;
                   4888:   jmean=0.;
1.224     brouard  4889: 
                   4890: /* Treating live states */
1.214     brouard  4891:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  4892:     mi=0;  /* First valid wave */
1.227     brouard  4893:     mli=0; /* Last valid wave */
1.126     brouard  4894:     m=firstpass;
1.214     brouard  4895:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  4896:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   4897:        mli=m-1;/* mw[++mi][i]=m-1; */
                   4898:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   4899:        mw[++mi][i]=m;
                   4900:        mli=m;
1.224     brouard  4901:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   4902:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  4903:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  4904:       }
1.227     brouard  4905:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  4906: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  4907:        break;
1.224     brouard  4908: #else
1.227     brouard  4909:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   4910:          if(firsthree == 0){
                   4911:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4912:            firsthree=1;
                   4913:          }
                   4914:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4915:          mw[++mi][i]=m;
                   4916:          mli=m;
                   4917:        }
                   4918:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   4919:          nbwarn++;
                   4920:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   4921:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4922:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4923:          }
                   4924:          break;
                   4925:        }
                   4926:        break;
1.224     brouard  4927: #endif
1.227     brouard  4928:       }/* End m >= lastpass */
1.126     brouard  4929:     }/* end while */
1.224     brouard  4930: 
1.227     brouard  4931:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  4932:     /* After last pass */
1.224     brouard  4933: /* Treating death states */
1.214     brouard  4934:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  4935:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   4936:       /* } */
1.126     brouard  4937:       mi++;    /* Death is another wave */
                   4938:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  4939:       /* Only death is a correct wave */
1.126     brouard  4940:       mw[mi][i]=m;
1.224     brouard  4941:     }
                   4942: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.227     brouard  4943:     else if ((int) andc[i] != 9999) { /* Status is negative. A death occured after lastpass, we can't take it into account because of potential bias */
1.216     brouard  4944:       /* m++; */
                   4945:       /* mi++; */
                   4946:       /* s[m][i]=nlstate+1;  /\* We are setting the status to the last of non live state *\/ */
                   4947:       /* mw[mi][i]=m; */
1.218     brouard  4948:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  4949:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   4950:          nbwarn++;
                   4951:          if(firstfiv==0){
                   4952:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4953:            firstfiv=1;
                   4954:          }else{
                   4955:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4956:          }
                   4957:        }else{ /* Death occured afer last wave potential bias */
                   4958:          nberr++;
                   4959:          if(firstwo==0){
                   4960:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4961:            firstwo=1;
                   4962:          }
                   4963:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4964:        }
1.218     brouard  4965:       }else{ /* end date of interview is known */
1.227     brouard  4966:        /* death is known but not confirmed by death status at any wave */
                   4967:        if(firstfour==0){
                   4968:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4969:          firstfour=1;
                   4970:        }
                   4971:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  4972:       }
1.224     brouard  4973:     } /* end if date of death is known */
                   4974: #endif
                   4975:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   4976:     /* wav[i]=mw[mi][i]; */
1.126     brouard  4977:     if(mi==0){
                   4978:       nbwarn++;
                   4979:       if(first==0){
1.227     brouard  4980:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   4981:        first=1;
1.126     brouard  4982:       }
                   4983:       if(first==1){
1.227     brouard  4984:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  4985:       }
                   4986:     } /* end mi==0 */
                   4987:   } /* End individuals */
1.214     brouard  4988:   /* wav and mw are no more changed */
1.223     brouard  4989:        
1.214     brouard  4990:   
1.126     brouard  4991:   for(i=1; i<=imx; i++){
                   4992:     for(mi=1; mi<wav[i];mi++){
                   4993:       if (stepm <=0)
1.227     brouard  4994:        dh[mi][i]=1;
1.126     brouard  4995:       else{
1.227     brouard  4996:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death */
                   4997:          if (agedc[i] < 2*AGESUP) {
                   4998:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   4999:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5000:            else if(j<0){
                   5001:              nberr++;
                   5002:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5003:              j=1; /* Temporary Dangerous patch */
                   5004:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5005:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5006:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5007:            }
                   5008:            k=k+1;
                   5009:            if (j >= jmax){
                   5010:              jmax=j;
                   5011:              ijmax=i;
                   5012:            }
                   5013:            if (j <= jmin){
                   5014:              jmin=j;
                   5015:              ijmin=i;
                   5016:            }
                   5017:            sum=sum+j;
                   5018:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5019:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5020:          }
                   5021:        }
                   5022:        else{
                   5023:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5024: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5025:                                        
1.227     brouard  5026:          k=k+1;
                   5027:          if (j >= jmax) {
                   5028:            jmax=j;
                   5029:            ijmax=i;
                   5030:          }
                   5031:          else if (j <= jmin){
                   5032:            jmin=j;
                   5033:            ijmin=i;
                   5034:          }
                   5035:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5036:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5037:          if(j<0){
                   5038:            nberr++;
                   5039:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5040:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5041:          }
                   5042:          sum=sum+j;
                   5043:        }
                   5044:        jk= j/stepm;
                   5045:        jl= j -jk*stepm;
                   5046:        ju= j -(jk+1)*stepm;
                   5047:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5048:          if(jl==0){
                   5049:            dh[mi][i]=jk;
                   5050:            bh[mi][i]=0;
                   5051:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5052:                  * to avoid the price of an extra matrix product in likelihood */
                   5053:            dh[mi][i]=jk+1;
                   5054:            bh[mi][i]=ju;
                   5055:          }
                   5056:        }else{
                   5057:          if(jl <= -ju){
                   5058:            dh[mi][i]=jk;
                   5059:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5060:                                 * is higher than the multiple of stepm and negative otherwise.
                   5061:                                 */
                   5062:          }
                   5063:          else{
                   5064:            dh[mi][i]=jk+1;
                   5065:            bh[mi][i]=ju;
                   5066:          }
                   5067:          if(dh[mi][i]==0){
                   5068:            dh[mi][i]=1; /* At least one step */
                   5069:            bh[mi][i]=ju; /* At least one step */
                   5070:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5071:          }
                   5072:        } /* end if mle */
1.126     brouard  5073:       }
                   5074:     } /* end wave */
                   5075:   }
                   5076:   jmean=sum/k;
                   5077:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5078:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5079: }
1.126     brouard  5080: 
                   5081: /*********** Tricode ****************************/
1.220     brouard  5082:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5083:  {
                   5084:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5085:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5086:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5087:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5088:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5089:     */
1.130     brouard  5090: 
1.242     brouard  5091:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5092:    int modmaxcovj=0; /* Modality max of covariates j */
                   5093:    int cptcode=0; /* Modality max of covariates j */
                   5094:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5095: 
                   5096: 
1.242     brouard  5097:    /* cptcoveff=0;  */
                   5098:    /* *cptcov=0; */
1.126     brouard  5099:  
1.242     brouard  5100:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  5101: 
1.242     brouard  5102:    /* Loop on covariates without age and products and no quantitative variable */
                   5103:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5104:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5105:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5106:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5107:        switch(Fixed[k]) {
                   5108:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5109:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5110:           ij=(int)(covar[Tvar[k]][i]);
                   5111:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5112:            * If product of Vn*Vm, still boolean *:
                   5113:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5114:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5115:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5116:              modality of the nth covariate of individual i. */
                   5117:           if (ij > modmaxcovj)
                   5118:             modmaxcovj=ij; 
                   5119:           else if (ij < modmincovj) 
                   5120:             modmincovj=ij; 
                   5121:           if ((ij < -1) && (ij > NCOVMAX)){
                   5122:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5123:             exit(1);
                   5124:           }else
                   5125:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5126:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5127:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5128:           /* getting the maximum value of the modality of the covariate
                   5129:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5130:              female ies 1, then modmaxcovj=1.
                   5131:           */
                   5132:         } /* end for loop on individuals i */
                   5133:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5134:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5135:         cptcode=modmaxcovj;
                   5136:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5137:         /*for (i=0; i<=cptcode; i++) {*/
                   5138:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5139:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5140:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5141:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5142:             if( j != -1){
                   5143:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5144:                                  covariate for which somebody answered excluding 
                   5145:                                  undefined. Usually 2: 0 and 1. */
                   5146:             }
                   5147:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5148:                                     covariate for which somebody answered including 
                   5149:                                     undefined. Usually 3: -1, 0 and 1. */
                   5150:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5151:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5152:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5153:                        
1.242     brouard  5154:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5155:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5156:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5157:         /* modmincovj=3; modmaxcovj = 7; */
                   5158:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5159:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5160:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5161:         /* nbcode[Tvar[j]][ij]=k; */
                   5162:         /* nbcode[Tvar[j]][1]=0; */
                   5163:         /* nbcode[Tvar[j]][2]=1; */
                   5164:         /* nbcode[Tvar[j]][3]=2; */
                   5165:         /* To be continued (not working yet). */
                   5166:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5167:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5168:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5169:             break;
                   5170:           }
                   5171:           ij++;
                   5172:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5173:           cptcode = ij; /* New max modality for covar j */
                   5174:         } /* end of loop on modality i=-1 to 1 or more */
                   5175:         break;
                   5176:        case 1: /* Testing on varying covariate, could be simple and
                   5177:                * should look at waves or product of fixed *
                   5178:                * varying. No time to test -1, assuming 0 and 1 only */
                   5179:         ij=0;
                   5180:         for(i=0; i<=1;i++){
                   5181:           nbcode[Tvar[k]][++ij]=i;
                   5182:         }
                   5183:         break;
                   5184:        default:
                   5185:         break;
                   5186:        } /* end switch */
                   5187:      } /* end dummy test */
                   5188:     
                   5189:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5190:      /*        /\*recode from 0 *\/ */
                   5191:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5192:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5193:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5194:      /*        } */
                   5195:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5196:      /*        if (ij > ncodemax[j]) { */
                   5197:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5198:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5199:      /*          break; */
                   5200:      /*        } */
                   5201:      /*   }  /\* end of loop on modality k *\/ */
                   5202:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5203:   
                   5204:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5205:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5206:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5207:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5208:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5209:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5210:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5211:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5212:   
                   5213:    ij=0;
                   5214:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5215:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5216:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5217:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5218:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5219:        /* If product not in single variable we don't print results */
                   5220:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5221:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5222:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5223:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5224:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5225:        if(Fixed[k]!=0)
                   5226:         anyvaryingduminmodel=1;
                   5227:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5228:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5229:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5230:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5231:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5232:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5233:      } 
                   5234:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5235:    /* ij--; */
                   5236:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5237:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5238:                * because they can be excluded from the model and real
                   5239:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5240:    for(j=ij+1; j<= cptcovt; j++){
                   5241:      Tvaraff[j]=0;
                   5242:      Tmodelind[j]=0;
                   5243:    }
                   5244:    for(j=ntveff+1; j<= cptcovt; j++){
                   5245:      TmodelInvind[j]=0;
                   5246:    }
                   5247:    /* To be sorted */
                   5248:    ;
                   5249:  }
1.126     brouard  5250: 
1.145     brouard  5251: 
1.126     brouard  5252: /*********** Health Expectancies ****************/
                   5253: 
1.235     brouard  5254:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5255: 
                   5256: {
                   5257:   /* Health expectancies, no variances */
1.164     brouard  5258:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5259:   int nhstepma, nstepma; /* Decreasing with age */
                   5260:   double age, agelim, hf;
                   5261:   double ***p3mat;
                   5262:   double eip;
                   5263: 
1.238     brouard  5264:   /* pstamp(ficreseij); */
1.126     brouard  5265:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5266:   fprintf(ficreseij,"# Age");
                   5267:   for(i=1; i<=nlstate;i++){
                   5268:     for(j=1; j<=nlstate;j++){
                   5269:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5270:     }
                   5271:     fprintf(ficreseij," e%1d. ",i);
                   5272:   }
                   5273:   fprintf(ficreseij,"\n");
                   5274: 
                   5275:   
                   5276:   if(estepm < stepm){
                   5277:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5278:   }
                   5279:   else  hstepm=estepm;   
                   5280:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5281:    * This is mainly to measure the difference between two models: for example
                   5282:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5283:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5284:    * progression in between and thus overestimating or underestimating according
                   5285:    * to the curvature of the survival function. If, for the same date, we 
                   5286:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5287:    * to compare the new estimate of Life expectancy with the same linear 
                   5288:    * hypothesis. A more precise result, taking into account a more precise
                   5289:    * curvature will be obtained if estepm is as small as stepm. */
                   5290: 
                   5291:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5292:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5293:      nhstepm is the number of hstepm from age to agelim 
                   5294:      nstepm is the number of stepm from age to agelin. 
                   5295:      Look at hpijx to understand the reason of that which relies in memory size
                   5296:      and note for a fixed period like estepm months */
                   5297:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5298:      survival function given by stepm (the optimization length). Unfortunately it
                   5299:      means that if the survival funtion is printed only each two years of age and if
                   5300:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5301:      results. So we changed our mind and took the option of the best precision.
                   5302:   */
                   5303:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5304: 
                   5305:   agelim=AGESUP;
                   5306:   /* If stepm=6 months */
                   5307:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5308:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5309:     
                   5310: /* nhstepm age range expressed in number of stepm */
                   5311:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5312:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5313:   /* if (stepm >= YEARM) hstepm=1;*/
                   5314:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5315:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5316: 
                   5317:   for (age=bage; age<=fage; age ++){ 
                   5318:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5319:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5320:     /* if (stepm >= YEARM) hstepm=1;*/
                   5321:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5322: 
                   5323:     /* If stepm=6 months */
                   5324:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5325:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5326:     
1.235     brouard  5327:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5328:     
                   5329:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5330:     
                   5331:     printf("%d|",(int)age);fflush(stdout);
                   5332:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5333:     
                   5334:     /* Computing expectancies */
                   5335:     for(i=1; i<=nlstate;i++)
                   5336:       for(j=1; j<=nlstate;j++)
                   5337:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5338:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5339:          
                   5340:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5341: 
                   5342:        }
                   5343: 
                   5344:     fprintf(ficreseij,"%3.0f",age );
                   5345:     for(i=1; i<=nlstate;i++){
                   5346:       eip=0;
                   5347:       for(j=1; j<=nlstate;j++){
                   5348:        eip +=eij[i][j][(int)age];
                   5349:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5350:       }
                   5351:       fprintf(ficreseij,"%9.4f", eip );
                   5352:     }
                   5353:     fprintf(ficreseij,"\n");
                   5354:     
                   5355:   }
                   5356:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5357:   printf("\n");
                   5358:   fprintf(ficlog,"\n");
                   5359:   
                   5360: }
                   5361: 
1.235     brouard  5362:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5363: 
                   5364: {
                   5365:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5366:      to initial status i, ei. .
1.126     brouard  5367:   */
                   5368:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5369:   int nhstepma, nstepma; /* Decreasing with age */
                   5370:   double age, agelim, hf;
                   5371:   double ***p3matp, ***p3matm, ***varhe;
                   5372:   double **dnewm,**doldm;
                   5373:   double *xp, *xm;
                   5374:   double **gp, **gm;
                   5375:   double ***gradg, ***trgradg;
                   5376:   int theta;
                   5377: 
                   5378:   double eip, vip;
                   5379: 
                   5380:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5381:   xp=vector(1,npar);
                   5382:   xm=vector(1,npar);
                   5383:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5384:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5385:   
                   5386:   pstamp(ficresstdeij);
                   5387:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5388:   fprintf(ficresstdeij,"# Age");
                   5389:   for(i=1; i<=nlstate;i++){
                   5390:     for(j=1; j<=nlstate;j++)
                   5391:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5392:     fprintf(ficresstdeij," e%1d. ",i);
                   5393:   }
                   5394:   fprintf(ficresstdeij,"\n");
                   5395: 
                   5396:   pstamp(ficrescveij);
                   5397:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5398:   fprintf(ficrescveij,"# Age");
                   5399:   for(i=1; i<=nlstate;i++)
                   5400:     for(j=1; j<=nlstate;j++){
                   5401:       cptj= (j-1)*nlstate+i;
                   5402:       for(i2=1; i2<=nlstate;i2++)
                   5403:        for(j2=1; j2<=nlstate;j2++){
                   5404:          cptj2= (j2-1)*nlstate+i2;
                   5405:          if(cptj2 <= cptj)
                   5406:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5407:        }
                   5408:     }
                   5409:   fprintf(ficrescveij,"\n");
                   5410:   
                   5411:   if(estepm < stepm){
                   5412:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5413:   }
                   5414:   else  hstepm=estepm;   
                   5415:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5416:    * This is mainly to measure the difference between two models: for example
                   5417:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5418:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5419:    * progression in between and thus overestimating or underestimating according
                   5420:    * to the curvature of the survival function. If, for the same date, we 
                   5421:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5422:    * to compare the new estimate of Life expectancy with the same linear 
                   5423:    * hypothesis. A more precise result, taking into account a more precise
                   5424:    * curvature will be obtained if estepm is as small as stepm. */
                   5425: 
                   5426:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5427:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5428:      nhstepm is the number of hstepm from age to agelim 
                   5429:      nstepm is the number of stepm from age to agelin. 
                   5430:      Look at hpijx to understand the reason of that which relies in memory size
                   5431:      and note for a fixed period like estepm months */
                   5432:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5433:      survival function given by stepm (the optimization length). Unfortunately it
                   5434:      means that if the survival funtion is printed only each two years of age and if
                   5435:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5436:      results. So we changed our mind and took the option of the best precision.
                   5437:   */
                   5438:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5439: 
                   5440:   /* If stepm=6 months */
                   5441:   /* nhstepm age range expressed in number of stepm */
                   5442:   agelim=AGESUP;
                   5443:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5444:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5445:   /* if (stepm >= YEARM) hstepm=1;*/
                   5446:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5447:   
                   5448:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5449:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5450:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5451:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5452:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5453:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5454: 
                   5455:   for (age=bage; age<=fage; age ++){ 
                   5456:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5457:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5458:     /* if (stepm >= YEARM) hstepm=1;*/
                   5459:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5460:                
1.126     brouard  5461:     /* If stepm=6 months */
                   5462:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5463:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5464:     
                   5465:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5466:                
1.126     brouard  5467:     /* Computing  Variances of health expectancies */
                   5468:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5469:        decrease memory allocation */
                   5470:     for(theta=1; theta <=npar; theta++){
                   5471:       for(i=1; i<=npar; i++){ 
1.222     brouard  5472:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5473:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5474:       }
1.235     brouard  5475:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5476:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5477:                        
1.126     brouard  5478:       for(j=1; j<= nlstate; j++){
1.222     brouard  5479:        for(i=1; i<=nlstate; i++){
                   5480:          for(h=0; h<=nhstepm-1; h++){
                   5481:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5482:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5483:          }
                   5484:        }
1.126     brouard  5485:       }
1.218     brouard  5486:                        
1.126     brouard  5487:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5488:        for(h=0; h<=nhstepm-1; h++){
                   5489:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5490:        }
1.126     brouard  5491:     }/* End theta */
                   5492:     
                   5493:     
                   5494:     for(h=0; h<=nhstepm-1; h++)
                   5495:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5496:        for(theta=1; theta <=npar; theta++)
                   5497:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5498:     
1.218     brouard  5499:                
1.222     brouard  5500:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5501:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5502:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5503:                
1.222     brouard  5504:     printf("%d|",(int)age);fflush(stdout);
                   5505:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5506:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5507:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5508:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5509:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5510:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5511:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5512:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5513:       }
                   5514:     }
1.218     brouard  5515:                
1.126     brouard  5516:     /* Computing expectancies */
1.235     brouard  5517:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5518:     for(i=1; i<=nlstate;i++)
                   5519:       for(j=1; j<=nlstate;j++)
1.222     brouard  5520:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5521:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5522:                                        
1.222     brouard  5523:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5524:                                        
1.222     brouard  5525:        }
1.218     brouard  5526:                
1.126     brouard  5527:     fprintf(ficresstdeij,"%3.0f",age );
                   5528:     for(i=1; i<=nlstate;i++){
                   5529:       eip=0.;
                   5530:       vip=0.;
                   5531:       for(j=1; j<=nlstate;j++){
1.222     brouard  5532:        eip += eij[i][j][(int)age];
                   5533:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5534:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5535:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5536:       }
                   5537:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5538:     }
                   5539:     fprintf(ficresstdeij,"\n");
1.218     brouard  5540:                
1.126     brouard  5541:     fprintf(ficrescveij,"%3.0f",age );
                   5542:     for(i=1; i<=nlstate;i++)
                   5543:       for(j=1; j<=nlstate;j++){
1.222     brouard  5544:        cptj= (j-1)*nlstate+i;
                   5545:        for(i2=1; i2<=nlstate;i2++)
                   5546:          for(j2=1; j2<=nlstate;j2++){
                   5547:            cptj2= (j2-1)*nlstate+i2;
                   5548:            if(cptj2 <= cptj)
                   5549:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5550:          }
1.126     brouard  5551:       }
                   5552:     fprintf(ficrescveij,"\n");
1.218     brouard  5553:                
1.126     brouard  5554:   }
                   5555:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5556:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5557:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5558:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5559:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5560:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5561:   printf("\n");
                   5562:   fprintf(ficlog,"\n");
1.218     brouard  5563:        
1.126     brouard  5564:   free_vector(xm,1,npar);
                   5565:   free_vector(xp,1,npar);
                   5566:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5567:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5568:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5569: }
1.218     brouard  5570:  
1.126     brouard  5571: /************ Variance ******************/
1.235     brouard  5572:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5573:  {
                   5574:    /* Variance of health expectancies */
                   5575:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5576:    /* double **newm;*/
                   5577:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5578:   
                   5579:    /* int movingaverage(); */
                   5580:    double **dnewm,**doldm;
                   5581:    double **dnewmp,**doldmp;
                   5582:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5583:    int k;
                   5584:    double *xp;
                   5585:    double **gp, **gm;  /* for var eij */
                   5586:    double ***gradg, ***trgradg; /*for var eij */
                   5587:    double **gradgp, **trgradgp; /* for var p point j */
                   5588:    double *gpp, *gmp; /* for var p point j */
                   5589:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5590:    double ***p3mat;
                   5591:    double age,agelim, hf;
                   5592:    /* double ***mobaverage; */
                   5593:    int theta;
                   5594:    char digit[4];
                   5595:    char digitp[25];
                   5596: 
                   5597:    char fileresprobmorprev[FILENAMELENGTH];
                   5598: 
                   5599:    if(popbased==1){
                   5600:      if(mobilav!=0)
                   5601:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5602:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5603:    }
                   5604:    else 
                   5605:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5606: 
1.218     brouard  5607:    /* if (mobilav!=0) { */
                   5608:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5609:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5610:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5611:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5612:    /*   } */
                   5613:    /* } */
                   5614: 
                   5615:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5616:    sprintf(digit,"%-d",ij);
                   5617:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5618:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5619:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5620:    strcat(fileresprobmorprev,fileresu);
                   5621:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5622:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5623:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5624:    }
                   5625:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5626:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5627:    pstamp(ficresprobmorprev);
                   5628:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5629:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5630:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5631:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5632:    }
                   5633:    for(j=1;j<=cptcoveff;j++) 
                   5634:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5635:    fprintf(ficresprobmorprev,"\n");
                   5636: 
1.218     brouard  5637:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5638:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5639:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5640:      for(i=1; i<=nlstate;i++)
                   5641:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5642:    }  
                   5643:    fprintf(ficresprobmorprev,"\n");
                   5644:   
                   5645:    fprintf(ficgp,"\n# Routine varevsij");
                   5646:    fprintf(ficgp,"\nunset title \n");
                   5647:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5648:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5649:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5650:    /*   } */
                   5651:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5652:    pstamp(ficresvij);
                   5653:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5654:    if(popbased==1)
                   5655:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5656:    else
                   5657:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5658:    fprintf(ficresvij,"# Age");
                   5659:    for(i=1; i<=nlstate;i++)
                   5660:      for(j=1; j<=nlstate;j++)
                   5661:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5662:    fprintf(ficresvij,"\n");
                   5663: 
                   5664:    xp=vector(1,npar);
                   5665:    dnewm=matrix(1,nlstate,1,npar);
                   5666:    doldm=matrix(1,nlstate,1,nlstate);
                   5667:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5668:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5669: 
                   5670:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5671:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5672:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5673:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5674:   
1.218     brouard  5675:    if(estepm < stepm){
                   5676:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5677:    }
                   5678:    else  hstepm=estepm;   
                   5679:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5680:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5681:       nhstepm is the number of hstepm from age to agelim 
                   5682:       nstepm is the number of stepm from age to agelim. 
                   5683:       Look at function hpijx to understand why because of memory size limitations, 
                   5684:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5685:       survival function given by stepm (the optimization length). Unfortunately it
                   5686:       means that if the survival funtion is printed every two years of age and if
                   5687:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5688:       results. So we changed our mind and took the option of the best precision.
                   5689:    */
                   5690:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5691:    agelim = AGESUP;
                   5692:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5693:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5694:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5695:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5696:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5697:      gp=matrix(0,nhstepm,1,nlstate);
                   5698:      gm=matrix(0,nhstepm,1,nlstate);
                   5699:                
                   5700:                
                   5701:      for(theta=1; theta <=npar; theta++){
                   5702:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5703:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5704:        }
                   5705:                        
1.242     brouard  5706:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5707:                        
                   5708:        if (popbased==1) {
                   5709:         if(mobilav ==0){
                   5710:           for(i=1; i<=nlstate;i++)
                   5711:             prlim[i][i]=probs[(int)age][i][ij];
                   5712:         }else{ /* mobilav */ 
                   5713:           for(i=1; i<=nlstate;i++)
                   5714:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5715:         }
                   5716:        }
                   5717:                        
1.235     brouard  5718:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5719:        for(j=1; j<= nlstate; j++){
                   5720:         for(h=0; h<=nhstepm; h++){
                   5721:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5722:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5723:         }
                   5724:        }
                   5725:        /* Next for computing probability of death (h=1 means
                   5726:          computed over hstepm matrices product = hstepm*stepm months) 
                   5727:          as a weighted average of prlim.
                   5728:        */
                   5729:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5730:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5731:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5732:        }    
                   5733:        /* end probability of death */
                   5734:                        
                   5735:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5736:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5737:                        
1.242     brouard  5738:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5739:                        
                   5740:        if (popbased==1) {
                   5741:         if(mobilav ==0){
                   5742:           for(i=1; i<=nlstate;i++)
                   5743:             prlim[i][i]=probs[(int)age][i][ij];
                   5744:         }else{ /* mobilav */ 
                   5745:           for(i=1; i<=nlstate;i++)
                   5746:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5747:         }
                   5748:        }
                   5749:                        
1.235     brouard  5750:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5751:                        
                   5752:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5753:         for(h=0; h<=nhstepm; h++){
                   5754:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5755:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5756:         }
                   5757:        }
                   5758:        /* This for computing probability of death (h=1 means
                   5759:          computed over hstepm matrices product = hstepm*stepm months) 
                   5760:          as a weighted average of prlim.
                   5761:        */
                   5762:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5763:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5764:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5765:        }    
                   5766:        /* end probability of death */
                   5767:                        
                   5768:        for(j=1; j<= nlstate; j++) /* vareij */
                   5769:         for(h=0; h<=nhstepm; h++){
                   5770:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5771:         }
                   5772:                        
                   5773:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5774:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5775:        }
                   5776:                        
                   5777:      } /* End theta */
                   5778:                
                   5779:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5780:                
                   5781:      for(h=0; h<=nhstepm; h++) /* veij */
                   5782:        for(j=1; j<=nlstate;j++)
                   5783:         for(theta=1; theta <=npar; theta++)
                   5784:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5785:                
                   5786:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5787:        for(theta=1; theta <=npar; theta++)
                   5788:         trgradgp[j][theta]=gradgp[theta][j];
                   5789:                
                   5790:                
                   5791:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5792:      for(i=1;i<=nlstate;i++)
                   5793:        for(j=1;j<=nlstate;j++)
                   5794:         vareij[i][j][(int)age] =0.;
                   5795:                
                   5796:      for(h=0;h<=nhstepm;h++){
                   5797:        for(k=0;k<=nhstepm;k++){
                   5798:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5799:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5800:         for(i=1;i<=nlstate;i++)
                   5801:           for(j=1;j<=nlstate;j++)
                   5802:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5803:        }
                   5804:      }
                   5805:                
                   5806:      /* pptj */
                   5807:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5808:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5809:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5810:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5811:         varppt[j][i]=doldmp[j][i];
                   5812:      /* end ppptj */
                   5813:      /*  x centered again */
                   5814:                
1.242     brouard  5815:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5816:                
                   5817:      if (popbased==1) {
                   5818:        if(mobilav ==0){
                   5819:         for(i=1; i<=nlstate;i++)
                   5820:           prlim[i][i]=probs[(int)age][i][ij];
                   5821:        }else{ /* mobilav */ 
                   5822:         for(i=1; i<=nlstate;i++)
                   5823:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   5824:        }
                   5825:      }
                   5826:                
                   5827:      /* This for computing probability of death (h=1 means
                   5828:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   5829:        as a weighted average of prlim.
                   5830:      */
1.235     brouard  5831:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  5832:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5833:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   5834:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   5835:      }    
                   5836:      /* end probability of death */
                   5837:                
                   5838:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   5839:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5840:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   5841:        for(i=1; i<=nlstate;i++){
                   5842:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   5843:        }
                   5844:      } 
                   5845:      fprintf(ficresprobmorprev,"\n");
                   5846:                
                   5847:      fprintf(ficresvij,"%.0f ",age );
                   5848:      for(i=1; i<=nlstate;i++)
                   5849:        for(j=1; j<=nlstate;j++){
                   5850:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   5851:        }
                   5852:      fprintf(ficresvij,"\n");
                   5853:      free_matrix(gp,0,nhstepm,1,nlstate);
                   5854:      free_matrix(gm,0,nhstepm,1,nlstate);
                   5855:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   5856:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   5857:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5858:    } /* End age */
                   5859:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   5860:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   5861:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   5862:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   5863:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   5864:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   5865:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   5866:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   5867:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5868:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   5869:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5870:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5871:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   5872:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   5873:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   5874:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   5875:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5876:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  5877:     */
1.218     brouard  5878:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   5879:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  5880: 
1.218     brouard  5881:    free_vector(xp,1,npar);
                   5882:    free_matrix(doldm,1,nlstate,1,nlstate);
                   5883:    free_matrix(dnewm,1,nlstate,1,npar);
                   5884:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5885:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   5886:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5887:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5888:    fclose(ficresprobmorprev);
                   5889:    fflush(ficgp);
                   5890:    fflush(fichtm); 
                   5891:  }  /* end varevsij */
1.126     brouard  5892: 
                   5893: /************ Variance of prevlim ******************/
1.235     brouard  5894:  void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  5895: {
1.205     brouard  5896:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  5897:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  5898: 
1.126     brouard  5899:   double **dnewm,**doldm;
                   5900:   int i, j, nhstepm, hstepm;
                   5901:   double *xp;
                   5902:   double *gp, *gm;
                   5903:   double **gradg, **trgradg;
1.208     brouard  5904:   double **mgm, **mgp;
1.126     brouard  5905:   double age,agelim;
                   5906:   int theta;
                   5907:   
                   5908:   pstamp(ficresvpl);
                   5909:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  5910:   fprintf(ficresvpl,"# Age ");
                   5911:   if(nresult >=1)
                   5912:     fprintf(ficresvpl," Result# ");
1.126     brouard  5913:   for(i=1; i<=nlstate;i++)
                   5914:       fprintf(ficresvpl," %1d-%1d",i,i);
                   5915:   fprintf(ficresvpl,"\n");
                   5916: 
                   5917:   xp=vector(1,npar);
                   5918:   dnewm=matrix(1,nlstate,1,npar);
                   5919:   doldm=matrix(1,nlstate,1,nlstate);
                   5920:   
                   5921:   hstepm=1*YEARM; /* Every year of age */
                   5922:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   5923:   agelim = AGESUP;
                   5924:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5925:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5926:     if (stepm >= YEARM) hstepm=1;
                   5927:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   5928:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  5929:     mgp=matrix(1,npar,1,nlstate);
                   5930:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  5931:     gp=vector(1,nlstate);
                   5932:     gm=vector(1,nlstate);
                   5933: 
                   5934:     for(theta=1; theta <=npar; theta++){
                   5935:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   5936:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5937:       }
1.209     brouard  5938:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5939:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5940:       else
1.235     brouard  5941:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5942:       for(i=1;i<=nlstate;i++){
1.126     brouard  5943:        gp[i] = prlim[i][i];
1.208     brouard  5944:        mgp[theta][i] = prlim[i][i];
                   5945:       }
1.126     brouard  5946:       for(i=1; i<=npar; i++) /* Computes gradient */
                   5947:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  5948:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5949:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5950:       else
1.235     brouard  5951:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5952:       for(i=1;i<=nlstate;i++){
1.126     brouard  5953:        gm[i] = prlim[i][i];
1.208     brouard  5954:        mgm[theta][i] = prlim[i][i];
                   5955:       }
1.126     brouard  5956:       for(i=1;i<=nlstate;i++)
                   5957:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  5958:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  5959:     } /* End theta */
                   5960: 
                   5961:     trgradg =matrix(1,nlstate,1,npar);
                   5962: 
                   5963:     for(j=1; j<=nlstate;j++)
                   5964:       for(theta=1; theta <=npar; theta++)
                   5965:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  5966:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5967:     /*   printf("\nmgm mgp %d ",(int)age); */
                   5968:     /*   for(j=1; j<=nlstate;j++){ */
                   5969:     /*         printf(" %d ",j); */
                   5970:     /*         for(theta=1; theta <=npar; theta++) */
                   5971:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   5972:     /*         printf("\n "); */
                   5973:     /*   } */
                   5974:     /* } */
                   5975:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5976:     /*   printf("\n gradg %d ",(int)age); */
                   5977:     /*   for(j=1; j<=nlstate;j++){ */
                   5978:     /*         printf("%d ",j); */
                   5979:     /*         for(theta=1; theta <=npar; theta++) */
                   5980:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   5981:     /*         printf("\n "); */
                   5982:     /*   } */
                   5983:     /* } */
1.126     brouard  5984: 
                   5985:     for(i=1;i<=nlstate;i++)
                   5986:       varpl[i][(int)age] =0.;
1.209     brouard  5987:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.205     brouard  5988:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   5989:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
                   5990:     }else{
1.126     brouard  5991:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   5992:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  5993:     }
1.126     brouard  5994:     for(i=1;i<=nlstate;i++)
                   5995:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   5996: 
                   5997:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  5998:     if(nresult >=1)
                   5999:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6000:     for(i=1; i<=nlstate;i++)
                   6001:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6002:     fprintf(ficresvpl,"\n");
                   6003:     free_vector(gp,1,nlstate);
                   6004:     free_vector(gm,1,nlstate);
1.208     brouard  6005:     free_matrix(mgm,1,npar,1,nlstate);
                   6006:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6007:     free_matrix(gradg,1,npar,1,nlstate);
                   6008:     free_matrix(trgradg,1,nlstate,1,npar);
                   6009:   } /* End age */
                   6010: 
                   6011:   free_vector(xp,1,npar);
                   6012:   free_matrix(doldm,1,nlstate,1,npar);
                   6013:   free_matrix(dnewm,1,nlstate,1,nlstate);
                   6014: 
                   6015: }
                   6016: 
                   6017: /************ Variance of one-step probabilities  ******************/
                   6018: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6019:  {
                   6020:    int i, j=0,  k1, l1, tj;
                   6021:    int k2, l2, j1,  z1;
                   6022:    int k=0, l;
                   6023:    int first=1, first1, first2;
                   6024:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6025:    double **dnewm,**doldm;
                   6026:    double *xp;
                   6027:    double *gp, *gm;
                   6028:    double **gradg, **trgradg;
                   6029:    double **mu;
                   6030:    double age, cov[NCOVMAX+1];
                   6031:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6032:    int theta;
                   6033:    char fileresprob[FILENAMELENGTH];
                   6034:    char fileresprobcov[FILENAMELENGTH];
                   6035:    char fileresprobcor[FILENAMELENGTH];
                   6036:    double ***varpij;
                   6037: 
                   6038:    strcpy(fileresprob,"PROB_"); 
                   6039:    strcat(fileresprob,fileres);
                   6040:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6041:      printf("Problem with resultfile: %s\n", fileresprob);
                   6042:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6043:    }
                   6044:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6045:    strcat(fileresprobcov,fileresu);
                   6046:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6047:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6048:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6049:    }
                   6050:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6051:    strcat(fileresprobcor,fileresu);
                   6052:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6053:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6054:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6055:    }
                   6056:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6057:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6058:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6059:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6060:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6061:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6062:    pstamp(ficresprob);
                   6063:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6064:    fprintf(ficresprob,"# Age");
                   6065:    pstamp(ficresprobcov);
                   6066:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6067:    fprintf(ficresprobcov,"# Age");
                   6068:    pstamp(ficresprobcor);
                   6069:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6070:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6071: 
                   6072: 
1.222     brouard  6073:    for(i=1; i<=nlstate;i++)
                   6074:      for(j=1; j<=(nlstate+ndeath);j++){
                   6075:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6076:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6077:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6078:      }  
                   6079:    /* fprintf(ficresprob,"\n");
                   6080:       fprintf(ficresprobcov,"\n");
                   6081:       fprintf(ficresprobcor,"\n");
                   6082:    */
                   6083:    xp=vector(1,npar);
                   6084:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6085:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6086:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6087:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6088:    first=1;
                   6089:    fprintf(ficgp,"\n# Routine varprob");
                   6090:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6091:    fprintf(fichtm,"\n");
                   6092: 
                   6093:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.</li>\n",optionfilehtmcov);
                   6094:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6095:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6096: and drawn. It helps understanding how is the covariance between two incidences.\
                   6097:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6098:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6099: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6100: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6101: standard deviations wide on each axis. <br>\
                   6102:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6103:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6104: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6105: 
1.222     brouard  6106:    cov[1]=1;
                   6107:    /* tj=cptcoveff; */
1.225     brouard  6108:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6109:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6110:    j1=0;
1.224     brouard  6111:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6112:      if  (cptcovn>0) {
                   6113:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6114:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6115:        fprintf(ficresprob, "**********\n#\n");
                   6116:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6117:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6118:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6119:                        
1.222     brouard  6120:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6121:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6122:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6123:                        
                   6124:                        
1.222     brouard  6125:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6126:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6127:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6128:                        
1.222     brouard  6129:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6130:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6131:        fprintf(ficresprobcor, "**********\n#");    
                   6132:        if(invalidvarcomb[j1]){
                   6133:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6134:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6135:         continue;
                   6136:        }
                   6137:      }
                   6138:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6139:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6140:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6141:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6142:      for (age=bage; age<=fage; age ++){ 
                   6143:        cov[2]=age;
                   6144:        if(nagesqr==1)
                   6145:         cov[3]= age*age;
                   6146:        for (k=1; k<=cptcovn;k++) {
                   6147:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6148:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6149:                                                                    * 1  1 1 1 1
                   6150:                                                                    * 2  2 1 1 1
                   6151:                                                                    * 3  1 2 1 1
                   6152:                                                                    */
                   6153:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6154:        }
                   6155:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6156:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6157:        for (k=1; k<=cptcovprod;k++)
                   6158:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6159:                        
                   6160:                        
1.222     brouard  6161:        for(theta=1; theta <=npar; theta++){
                   6162:         for(i=1; i<=npar; i++)
                   6163:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6164:                                
1.222     brouard  6165:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6166:                                
1.222     brouard  6167:         k=0;
                   6168:         for(i=1; i<= (nlstate); i++){
                   6169:           for(j=1; j<=(nlstate+ndeath);j++){
                   6170:             k=k+1;
                   6171:             gp[k]=pmmij[i][j];
                   6172:           }
                   6173:         }
1.220     brouard  6174:                                
1.222     brouard  6175:         for(i=1; i<=npar; i++)
                   6176:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6177:                                
1.222     brouard  6178:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6179:         k=0;
                   6180:         for(i=1; i<=(nlstate); i++){
                   6181:           for(j=1; j<=(nlstate+ndeath);j++){
                   6182:             k=k+1;
                   6183:             gm[k]=pmmij[i][j];
                   6184:           }
                   6185:         }
1.220     brouard  6186:                                
1.222     brouard  6187:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6188:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6189:        }
1.126     brouard  6190: 
1.222     brouard  6191:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6192:         for(theta=1; theta <=npar; theta++)
                   6193:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6194:                        
1.222     brouard  6195:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6196:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6197:                        
1.222     brouard  6198:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6199:                        
1.222     brouard  6200:        k=0;
                   6201:        for(i=1; i<=(nlstate); i++){
                   6202:         for(j=1; j<=(nlstate+ndeath);j++){
                   6203:           k=k+1;
                   6204:           mu[k][(int) age]=pmmij[i][j];
                   6205:         }
                   6206:        }
                   6207:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6208:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6209:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6210:                        
1.222     brouard  6211:        /*printf("\n%d ",(int)age);
                   6212:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6213:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6214:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6215:         }*/
1.220     brouard  6216:                        
1.222     brouard  6217:        fprintf(ficresprob,"\n%d ",(int)age);
                   6218:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6219:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6220:                        
1.222     brouard  6221:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6222:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6223:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6224:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6225:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6226:        }
                   6227:        i=0;
                   6228:        for (k=1; k<=(nlstate);k++){
                   6229:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6230:           i++;
                   6231:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6232:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6233:           for (j=1; j<=i;j++){
                   6234:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6235:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6236:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6237:           }
                   6238:         }
                   6239:        }/* end of loop for state */
                   6240:      } /* end of loop for age */
                   6241:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6242:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6243:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6244:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6245:     
                   6246:      /* Confidence intervalle of pij  */
                   6247:      /*
                   6248:        fprintf(ficgp,"\nunset parametric;unset label");
                   6249:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6250:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6251:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6252:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6253:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6254:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6255:      */
                   6256:                
                   6257:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6258:      first1=1;first2=2;
                   6259:      for (k2=1; k2<=(nlstate);k2++){
                   6260:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6261:         if(l2==k2) continue;
                   6262:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6263:         for (k1=1; k1<=(nlstate);k1++){
                   6264:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6265:             if(l1==k1) continue;
                   6266:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6267:             if(i<=j) continue;
                   6268:             for (age=bage; age<=fage; age ++){ 
                   6269:               if ((int)age %5==0){
                   6270:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6271:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6272:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6273:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6274:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6275:                 c12=cv12/sqrt(v1*v2);
                   6276:                 /* Computing eigen value of matrix of covariance */
                   6277:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6278:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6279:                 if ((lc2 <0) || (lc1 <0) ){
                   6280:                   if(first2==1){
                   6281:                     first1=0;
                   6282:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6283:                   }
                   6284:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6285:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6286:                   /* lc2=fabs(lc2); */
                   6287:                 }
1.220     brouard  6288:                                                                
1.222     brouard  6289:                 /* Eigen vectors */
                   6290:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   6291:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6292:                 v21=(lc1-v1)/cv12*v11;
                   6293:                 v12=-v21;
                   6294:                 v22=v11;
                   6295:                 tnalp=v21/v11;
                   6296:                 if(first1==1){
                   6297:                   first1=0;
                   6298:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6299:                 }
                   6300:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6301:                 /*printf(fignu*/
                   6302:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6303:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6304:                 if(first==1){
                   6305:                   first=0;
                   6306:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6307:                   fprintf(ficgp,"\nset parametric;unset label");
                   6308:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6309:                   fprintf(ficgp,"\nset ter svg size 640, 480");
                   6310:                   fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6311:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6312: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6313:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6314:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6315:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6316:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6317:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6318:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6319:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6320:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
                   6321:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                                                         \
                   6322:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6323:                 }else{
                   6324:                   first=0;
                   6325:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6326:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6327:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6328:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
                   6329:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                 \
                   6330:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6331:                 }/* if first */
                   6332:               } /* age mod 5 */
                   6333:             } /* end loop age */
                   6334:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6335:             first=1;
                   6336:           } /*l12 */
                   6337:         } /* k12 */
                   6338:        } /*l1 */
                   6339:      }/* k1 */
                   6340:    }  /* loop on combination of covariates j1 */
                   6341:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6342:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6343:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6344:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6345:    free_vector(xp,1,npar);
                   6346:    fclose(ficresprob);
                   6347:    fclose(ficresprobcov);
                   6348:    fclose(ficresprobcor);
                   6349:    fflush(ficgp);
                   6350:    fflush(fichtmcov);
                   6351:  }
1.126     brouard  6352: 
                   6353: 
                   6354: /******************* Printing html file ***********/
1.201     brouard  6355: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6356:                  int lastpass, int stepm, int weightopt, char model[],\
                   6357:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.217     brouard  6358:                  int popforecast, int prevfcast, int backcast, int estepm , \
1.213     brouard  6359:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   6360:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.237     brouard  6361:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6362: 
                   6363:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6364:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6365: </ul>");
1.237     brouard  6366:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6367: </ul>", model);
1.214     brouard  6368:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6369:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6370:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6371:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6372:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6373:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6374:    fprintf(fichtm,"\
                   6375:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6376:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6377:    fprintf(fichtm,"\
1.217     brouard  6378:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6379:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6380:    fprintf(fichtm,"\
1.126     brouard  6381:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6382:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6383:    fprintf(fichtm,"\
1.217     brouard  6384:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6385:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6386:    fprintf(fichtm,"\
1.211     brouard  6387:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6388:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6389:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6390:    if(prevfcast==1){
                   6391:      fprintf(fichtm,"\
                   6392:  - Prevalence projections by age and states:                           \
1.201     brouard  6393:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6394:    }
1.126     brouard  6395: 
1.222     brouard  6396:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
1.126     brouard  6397: 
1.225     brouard  6398:    m=pow(2,cptcoveff);
1.222     brouard  6399:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6400: 
1.222     brouard  6401:    jj1=0;
1.237     brouard  6402: 
                   6403:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6404:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253   ! brouard  6405:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6406:        continue;
1.220     brouard  6407: 
1.222     brouard  6408:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6409:      jj1++;
                   6410:      if (cptcovn > 0) {
                   6411:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6412:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6413:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6414:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6415:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6416:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6417:        }
1.237     brouard  6418:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6419:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6420:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6421:       }
                   6422:        
1.230     brouard  6423:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6424:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6425:        if(invalidvarcomb[k1]){
                   6426:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6427:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6428:         continue;
                   6429:        }
                   6430:      }
                   6431:      /* aij, bij */
1.241     brouard  6432:      fprintf(fichtm,"<br>- Logit model (yours is: 1+age+%s), for example: logit(pij)=log(pij/pii)= aij+ bij age + V1 age + etc. as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
                   6433: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6434:      /* Pij */
1.241     brouard  6435:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6436: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6437:      /* Quasi-incidences */
                   6438:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6439:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6440:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6441: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6442: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6443:      /* Survival functions (period) in state j */
                   6444:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6445:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6446: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6447:      }
                   6448:      /* State specific survival functions (period) */
                   6449:      for(cpt=1; cpt<=nlstate;cpt++){
                   6450:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6451:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.241     brouard  6452:  <a href=\"%s_%d-%d-%d.svg\">%s_%d%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6453:      }
                   6454:      /* Period (stable) prevalence in each health state */
                   6455:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6456:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6457: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6458:      }
                   6459:      if(backcast==1){
                   6460:        /* Period (stable) back prevalence in each health state */
                   6461:        for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6462:         fprintf(fichtm,"<br>\n- Convergence to period (stable) back prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6463: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6464:        }
1.217     brouard  6465:      }
1.222     brouard  6466:      if(prevfcast==1){
                   6467:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6468:        for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6469:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f) up to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6470: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6471:        }
                   6472:      }
1.220     brouard  6473:         
1.222     brouard  6474:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6475:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6476: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6477:      }
                   6478:      /* } /\* end i1 *\/ */
                   6479:    }/* End k1 */
                   6480:    fprintf(fichtm,"</ul>");
1.126     brouard  6481: 
1.222     brouard  6482:    fprintf(fichtm,"\
1.126     brouard  6483: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6484:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6485:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6486: But because parameters are usually highly correlated (a higher incidence of disability \
                   6487: and a higher incidence of recovery can give very close observed transition) it might \
                   6488: be very useful to look not only at linear confidence intervals estimated from the \
                   6489: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6490: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6491: covariance matrix of the one-step probabilities. \
                   6492: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6493: 
1.222     brouard  6494:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6495:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6496:    fprintf(fichtm,"\
1.126     brouard  6497:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6498:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6499: 
1.222     brouard  6500:    fprintf(fichtm,"\
1.126     brouard  6501:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6502:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6503:    fprintf(fichtm,"\
1.126     brouard  6504:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6505:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6506:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6507:    fprintf(fichtm,"\
1.126     brouard  6508:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6509:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6510:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6511:    fprintf(fichtm,"\
1.128     brouard  6512:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6513:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6514:    fprintf(fichtm,"\
1.128     brouard  6515:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6516:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6517:    fprintf(fichtm,"\
1.126     brouard  6518:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6519:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6520: 
                   6521: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6522: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6523: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6524: /*     <br>",fileres,fileres,fileres,fileres); */
                   6525: /*  else  */
                   6526: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6527:    fflush(fichtm);
                   6528:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6529: 
1.225     brouard  6530:    m=pow(2,cptcoveff);
1.222     brouard  6531:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6532: 
1.222     brouard  6533:    jj1=0;
1.237     brouard  6534: 
1.241     brouard  6535:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6536:    for(k1=1; k1<=m;k1++){
1.253   ! brouard  6537:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6538:        continue;
1.222     brouard  6539:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6540:      jj1++;
1.126     brouard  6541:      if (cptcovn > 0) {
                   6542:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6543:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6544:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6545:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6546:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6547:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6548:       }
                   6549: 
1.126     brouard  6550:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6551: 
1.222     brouard  6552:        if(invalidvarcomb[k1]){
                   6553:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6554:         continue;
                   6555:        }
1.126     brouard  6556:      }
                   6557:      for(cpt=1; cpt<=nlstate;cpt++) {
1.218     brouard  6558:        fprintf(fichtm,"\n<br>- Observed (cross-sectional) and period (incidence based) \
1.241     brouard  6559: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
                   6560: <img src=\"%s_%d-%d-%d.svg\">",cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  6561:      }
                   6562:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6563: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6564: true period expectancies (those weighted with period prevalences are also\
                   6565:  drawn in addition to the population based expectancies computed using\
1.241     brouard  6566:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   6567: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  6568:      /* } /\* end i1 *\/ */
                   6569:    }/* End k1 */
1.241     brouard  6570:   }/* End nres */
1.222     brouard  6571:    fprintf(fichtm,"</ul>");
                   6572:    fflush(fichtm);
1.126     brouard  6573: }
                   6574: 
                   6575: /******************* Gnuplot file **************/
1.223     brouard  6576: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[]){
1.126     brouard  6577: 
                   6578:   char dirfileres[132],optfileres[132];
1.223     brouard  6579:   char gplotcondition[132];
1.237     brouard  6580:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6581:   int lv=0, vlv=0, kl=0;
1.130     brouard  6582:   int ng=0;
1.201     brouard  6583:   int vpopbased;
1.223     brouard  6584:   int ioffset; /* variable offset for columns */
1.235     brouard  6585:   int nres=0; /* Index of resultline */
1.219     brouard  6586: 
1.126     brouard  6587: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6588: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6589: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6590: /*   } */
                   6591: 
                   6592:   /*#ifdef windows */
                   6593:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6594:   /*#endif */
1.225     brouard  6595:   m=pow(2,cptcoveff);
1.126     brouard  6596: 
1.202     brouard  6597:   /* Contribution to likelihood */
                   6598:   /* Plot the probability implied in the likelihood */
1.223     brouard  6599:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6600:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6601:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6602:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6603: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6604:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6605: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6606:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6607:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6608:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6609:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6610:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6611:   for (i=1; i<= nlstate ; i ++) {
                   6612:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6613:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6614:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6615:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6616:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6617:     }
                   6618:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6619:   }
                   6620:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6621:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6622:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6623:   fprintf(ficgp,"\nset out;unset log\n");
                   6624:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6625: 
1.126     brouard  6626:   strcpy(dirfileres,optionfilefiname);
                   6627:   strcpy(optfileres,"vpl");
1.223     brouard  6628:   /* 1eme*/
1.238     brouard  6629:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   6630:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  6631:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  6632:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253   ! brouard  6633:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6634:          continue;
                   6635:        /* We are interested in selected combination by the resultline */
1.246     brouard  6636:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  6637:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
                   6638:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6639:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   6640:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6641:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6642:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6643:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   6644:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  6645:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  6646:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6647:        }
                   6648:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  6649:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  6650:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6651:        }       
1.246     brouard  6652:        /* printf("\n#\n"); */
1.238     brouard  6653:        fprintf(ficgp,"\n#\n");
                   6654:        if(invalidvarcomb[k1]){
                   6655:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6656:          continue;
                   6657:        }
1.235     brouard  6658:       
1.241     brouard  6659:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   6660:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
                   6661:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres);
1.235     brouard  6662:       
1.238     brouard  6663:        for (i=1; i<= nlstate ; i ++) {
                   6664:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6665:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   6666:        }
1.242     brouard  6667:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres);
1.238     brouard  6668:        for (i=1; i<= nlstate ; i ++) {
                   6669:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6670:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6671:        } 
1.242     brouard  6672:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); 
1.238     brouard  6673:        for (i=1; i<= nlstate ; i ++) {
                   6674:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6675:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6676:        }  
                   6677:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1));
                   6678:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   6679:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  6680:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  6681:          if(cptcoveff ==0){
1.245     brouard  6682:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  6683:          }else{
                   6684:            kl=0;
                   6685:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   6686:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6687:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6688:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6689:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6690:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  6691:              kl++;
1.238     brouard  6692:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6693:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6694:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6695:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6696:              if(k==cptcoveff){
1.245     brouard  6697:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  6698:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  6699:              }else{
                   6700:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   6701:                kl++;
                   6702:              }
                   6703:            } /* end covariate */
                   6704:          } /* end if no covariate */
                   6705:        } /* end if backcast */
                   6706:        fprintf(ficgp,"\nset out \n");
                   6707:       } /* nres */
1.201     brouard  6708:     } /* k1 */
                   6709:   } /* cpt */
1.235     brouard  6710: 
                   6711:   
1.126     brouard  6712:   /*2 eme*/
1.238     brouard  6713:   for (k1=1; k1<= m ; k1 ++){  
                   6714:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253   ! brouard  6715:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6716:        continue;
                   6717:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
                   6718:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  6719:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6720:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6721:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6722:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6723:        vlv= nbcode[Tvaraff[k]][lv];
                   6724:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6725:       }
1.237     brouard  6726:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  6727:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  6728:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  6729:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  6730:       }
1.211     brouard  6731:       fprintf(ficgp,"\n#\n");
1.223     brouard  6732:       if(invalidvarcomb[k1]){
                   6733:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6734:        continue;
                   6735:       }
1.219     brouard  6736:                        
1.241     brouard  6737:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  6738:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
                   6739:        if(vpopbased==0)
                   6740:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
                   6741:        else
                   6742:          fprintf(ficgp,"\nreplot ");
                   6743:        for (i=1; i<= nlstate+1 ; i ++) {
                   6744:          k=2*i;
                   6745:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1, vpopbased);
                   6746:          for (j=1; j<= nlstate+1 ; j ++) {
                   6747:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6748:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6749:          }   
                   6750:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   6751:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
                   6752:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6753:          for (j=1; j<= nlstate+1 ; j ++) {
                   6754:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6755:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6756:          }   
                   6757:          fprintf(ficgp,"\" t\"\" w l lt 0,");
                   6758:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6759:          for (j=1; j<= nlstate+1 ; j ++) {
                   6760:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6761:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6762:          }   
                   6763:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   6764:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   6765:        } /* state */
                   6766:       } /* vpopbased */
1.244     brouard  6767:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  6768:     } /* end nres */
                   6769:   } /* k1 end 2 eme*/
                   6770:        
                   6771:        
                   6772:   /*3eme*/
                   6773:   for (k1=1; k1<= m ; k1 ++){
                   6774:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253   ! brouard  6775:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6776:        continue;
                   6777: 
                   6778:       for (cpt=1; cpt<= nlstate ; cpt ++) {
                   6779:        fprintf(ficgp,"\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
                   6780:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6781:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6782:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6783:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6784:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6785:          vlv= nbcode[Tvaraff[k]][lv];
                   6786:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6787:        }
                   6788:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6789:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6790:        }       
                   6791:        fprintf(ficgp,"\n#\n");
                   6792:        if(invalidvarcomb[k1]){
                   6793:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6794:          continue;
                   6795:        }
                   6796:                        
                   6797:        /*       k=2+nlstate*(2*cpt-2); */
                   6798:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  6799:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.238     brouard  6800:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.201     brouard  6801: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),k1-1,k1-1,k,cpt);
1.238     brouard  6802:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6803:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6804:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   6805:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6806:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6807:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  6808:                                
1.238     brouard  6809:        */
                   6810:        for (i=1; i< nlstate ; i ++) {
                   6811:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+i,cpt,i+1);
                   6812:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  6813:                                
1.238     brouard  6814:        } 
                   6815:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+nlstate,cpt);
                   6816:       }
                   6817:     } /* end nres */
                   6818:   } /* end kl 3eme */
1.126     brouard  6819:   
1.223     brouard  6820:   /* 4eme */
1.201     brouard  6821:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  6822:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   6823:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253   ! brouard  6824:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  6825:        continue;
1.238     brouard  6826:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
                   6827:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   6828:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6829:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6830:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6831:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6832:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6833:          vlv= nbcode[Tvaraff[k]][lv];
                   6834:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6835:        }
                   6836:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6837:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6838:        }       
                   6839:        fprintf(ficgp,"\n#\n");
                   6840:        if(invalidvarcomb[k1]){
                   6841:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6842:          continue;
1.223     brouard  6843:        }
1.238     brouard  6844:       
1.241     brouard  6845:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.238     brouard  6846:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6847: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6848:        k=3;
                   6849:        for (i=1; i<= nlstate ; i ++){
                   6850:          if(i==1){
                   6851:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6852:          }else{
                   6853:            fprintf(ficgp,", '' ");
                   6854:          }
                   6855:          l=(nlstate+ndeath)*(i-1)+1;
                   6856:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6857:          for (j=2; j<= nlstate+ndeath ; j ++)
                   6858:            fprintf(ficgp,"+$%d",k+l+j-1);
                   6859:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   6860:        } /* nlstate */
                   6861:        fprintf(ficgp,"\nset out\n");
                   6862:       } /* end cpt state*/ 
                   6863:     } /* end nres */
                   6864:   } /* end covariate k1 */  
                   6865: 
1.220     brouard  6866: /* 5eme */
1.201     brouard  6867:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  6868:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   6869:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253   ! brouard  6870:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  6871:        continue;
1.238     brouard  6872:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
                   6873:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   6874:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6875:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6876:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6877:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6878:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6879:          vlv= nbcode[Tvaraff[k]][lv];
                   6880:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6881:        }
                   6882:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6883:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6884:        }       
                   6885:        fprintf(ficgp,"\n#\n");
                   6886:        if(invalidvarcomb[k1]){
                   6887:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6888:          continue;
                   6889:        }
1.227     brouard  6890:       
1.241     brouard  6891:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.238     brouard  6892:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6893: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6894:        k=3;
                   6895:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6896:          if(j==1)
                   6897:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6898:          else
                   6899:            fprintf(ficgp,", '' ");
                   6900:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6901:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   6902:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   6903:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   6904:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   6905:        } /* nlstate */
                   6906:        fprintf(ficgp,", '' ");
                   6907:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   6908:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6909:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6910:          if(j < nlstate)
                   6911:            fprintf(ficgp,"$%d +",k+l);
                   6912:          else
                   6913:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   6914:        }
                   6915:        fprintf(ficgp,"\nset out\n");
                   6916:       } /* end cpt state*/ 
                   6917:     } /* end covariate */  
                   6918:   } /* end nres */
1.227     brouard  6919:   
1.220     brouard  6920: /* 6eme */
1.202     brouard  6921:   /* CV preval stable (period) for each covariate */
1.237     brouard  6922:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6923:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253   ! brouard  6924:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6925:       continue;
1.153     brouard  6926:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6927:       
1.211     brouard  6928:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  6929:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  6930:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6931:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6932:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6933:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6934:        vlv= nbcode[Tvaraff[k]][lv];
                   6935:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6936:       }
1.237     brouard  6937:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6938:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6939:       }        
1.211     brouard  6940:       fprintf(ficgp,"\n#\n");
1.223     brouard  6941:       if(invalidvarcomb[k1]){
1.227     brouard  6942:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6943:        continue;
1.223     brouard  6944:       }
1.227     brouard  6945:       
1.241     brouard  6946:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.126     brouard  6947:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  6948: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6949:       k=3; /* Offset */
1.153     brouard  6950:       for (i=1; i<= nlstate ; i ++){
1.227     brouard  6951:        if(i==1)
                   6952:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6953:        else
                   6954:          fprintf(ficgp,", '' ");
                   6955:        l=(nlstate+ndeath)*(i-1)+1;
                   6956:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6957:        for (j=2; j<= nlstate ; j ++)
                   6958:          fprintf(ficgp,"+$%d",k+l+j-1);
                   6959:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  6960:       } /* nlstate */
1.201     brouard  6961:       fprintf(ficgp,"\nset out\n");
1.153     brouard  6962:     } /* end cpt state*/ 
                   6963:   } /* end covariate */  
1.227     brouard  6964:   
                   6965:   
1.220     brouard  6966: /* 7eme */
1.218     brouard  6967:   if(backcast == 1){
1.217     brouard  6968:     /* CV back preval stable (period) for each covariate */
1.237     brouard  6969:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6970:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253   ! brouard  6971:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6972:        continue;
1.218     brouard  6973:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6974:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
                   6975:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6976:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6977:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6978:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  6979:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  6980:          vlv= nbcode[Tvaraff[k]][lv];
                   6981:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6982:        }
1.237     brouard  6983:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6984:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6985:        }       
1.227     brouard  6986:        fprintf(ficgp,"\n#\n");
                   6987:        if(invalidvarcomb[k1]){
                   6988:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6989:          continue;
                   6990:        }
                   6991:        
1.241     brouard  6992:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.227     brouard  6993:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  6994: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  6995:        k=3; /* Offset */
                   6996:        for (i=1; i<= nlstate ; i ++){
                   6997:          if(i==1)
                   6998:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   6999:          else
                   7000:            fprintf(ficgp,", '' ");
                   7001:          /* l=(nlstate+ndeath)*(i-1)+1; */
                   7002:          l=(nlstate+ndeath)*(cpt-1)+1;
                   7003:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7004:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
                   7005:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+(cpt-1)+i-1); /* a vérifier */
                   7006:          /* for (j=2; j<= nlstate ; j ++) */
                   7007:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7008:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
                   7009:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",i,cpt);
                   7010:        } /* nlstate */
                   7011:        fprintf(ficgp,"\nset out\n");
1.218     brouard  7012:       } /* end cpt state*/ 
                   7013:     } /* end covariate */  
                   7014:   } /* End if backcast */
                   7015:   
1.223     brouard  7016:   /* 8eme */
1.218     brouard  7017:   if(prevfcast==1){
                   7018:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7019:     
1.237     brouard  7020:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7021:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253   ! brouard  7022:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7023:        continue;
1.211     brouard  7024:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  7025:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7026:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7027:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7028:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7029:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7030:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7031:          vlv= nbcode[Tvaraff[k]][lv];
                   7032:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7033:        }
1.237     brouard  7034:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7035:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7036:        }       
1.227     brouard  7037:        fprintf(ficgp,"\n#\n");
                   7038:        if(invalidvarcomb[k1]){
                   7039:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7040:          continue;
                   7041:        }
                   7042:        
                   7043:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7044:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.227     brouard  7045:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7046: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7047:        for (i=1; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7048:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7049:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7050:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7051:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7052:          if(i==1){
                   7053:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7054:          }else{
                   7055:            fprintf(ficgp,",\\\n '' ");
                   7056:          }
                   7057:          if(cptcoveff ==0){ /* No covariate */
                   7058:            ioffset=2; /* Age is in 2 */
                   7059:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7060:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7061:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7062:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7063:            fprintf(ficgp," u %d:(", ioffset); 
                   7064:            if(i==nlstate+1)
                   7065:              fprintf(ficgp," $%d/(1.-$%d)) t 'pw.%d' with line ",      \
                   7066:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7067:            else
                   7068:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7069:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7070:          }else{ /* more than 2 covariates */
                   7071:            if(cptcoveff ==1){
                   7072:              ioffset=4; /* Age is in 4 */
                   7073:            }else{
                   7074:              ioffset=6; /* Age is in 6 */
                   7075:              /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7076:              /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7077:            }   
                   7078:            fprintf(ficgp," u %d:(",ioffset); 
                   7079:            kl=0;
                   7080:            strcpy(gplotcondition,"(");
                   7081:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7082:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7083:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7084:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7085:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7086:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7087:              kl++;
                   7088:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7089:              kl++;
                   7090:              if(k <cptcoveff && cptcoveff>1)
                   7091:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7092:            }
                   7093:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7094:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7095:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7096:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7097:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7098:            if(i==nlstate+1){
                   7099:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p.%d' with line ", gplotcondition, \
                   7100:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7101:            }else{
                   7102:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7103:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7104:            }
                   7105:          } /* end if covariate */
                   7106:        } /* nlstate */
                   7107:        fprintf(ficgp,"\nset out\n");
1.223     brouard  7108:       } /* end cpt state*/
                   7109:     } /* end covariate */
                   7110:   } /* End if prevfcast */
1.227     brouard  7111:   
                   7112:   
1.238     brouard  7113:   /* 9eme writing MLE parameters */
                   7114:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7115:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7116:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7117:     for(k=1; k <=(nlstate+ndeath); k++){
                   7118:       if (k != i) {
1.227     brouard  7119:        fprintf(ficgp,"#   current state %d\n",k);
                   7120:        for(j=1; j <=ncovmodel; j++){
                   7121:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7122:          jk++; 
                   7123:        }
                   7124:        fprintf(ficgp,"\n");
1.126     brouard  7125:       }
                   7126:     }
1.223     brouard  7127:   }
1.187     brouard  7128:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7129:   
1.145     brouard  7130:   /*goto avoid;*/
1.238     brouard  7131:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7132:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7133:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7134:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7135:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7136:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7137:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7138:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7139:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7140:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7141:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7142:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7143:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7144:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7145:   fprintf(ficgp,"#\n");
1.223     brouard  7146:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7147:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7148:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7149:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.237     brouard  7150:     fprintf(ficgp,"#   jk=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7151:     for(jk=1; jk <=m; jk++)  /* For each combination of covariate */
                   7152:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253   ! brouard  7153:       if(m != 1 && TKresult[nres]!= jk)
1.237     brouard  7154:        continue;
                   7155:       fprintf(ficgp,"# Combination of dummy  jk=%d and ",jk);
                   7156:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7157:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7158:       }        
                   7159:       fprintf(ficgp,"\n#\n");
1.241     brouard  7160:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng,nres);
1.223     brouard  7161:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7162:       if (ng==1){
                   7163:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7164:        fprintf(ficgp,"\nunset log y");
                   7165:       }else if (ng==2){
                   7166:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7167:        fprintf(ficgp,"\nset log y");
                   7168:       }else if (ng==3){
                   7169:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7170:        fprintf(ficgp,"\nset log y");
                   7171:       }else
                   7172:        fprintf(ficgp,"\nunset title ");
                   7173:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7174:       i=1;
                   7175:       for(k2=1; k2<=nlstate; k2++) {
                   7176:        k3=i;
                   7177:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7178:          if (k != k2){
                   7179:            switch( ng) {
                   7180:            case 1:
                   7181:              if(nagesqr==0)
                   7182:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7183:              else /* nagesqr =1 */
                   7184:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7185:              break;
                   7186:            case 2: /* ng=2 */
                   7187:              if(nagesqr==0)
                   7188:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7189:              else /* nagesqr =1 */
                   7190:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7191:              break;
                   7192:            case 3:
                   7193:              if(nagesqr==0)
                   7194:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7195:              else /* nagesqr =1 */
                   7196:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7197:              break;
                   7198:            }
                   7199:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7200:            ijp=1; /* product no age */
                   7201:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7202:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7203:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.237     brouard  7204:              if(j==Tage[ij]) { /* Product by age */
                   7205:                if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
1.238     brouard  7206:                  if(DummyV[j]==0){
1.237     brouard  7207:                    fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7208:                  }else{ /* quantitative */
                   7209:                    fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7210:                    /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7211:                  }
                   7212:                  ij++;
                   7213:                }
                   7214:              }else if(j==Tprod[ijp]) { /* */ 
                   7215:                /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7216:                if(ijp <=cptcovprod) { /* Product */
1.238     brouard  7217:                  if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7218:                    if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
1.237     brouard  7219:                      /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],nbcode[Tvard[ijp][2]][codtabm(jk,j)]); */
                   7220:                      fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7221:                    }else{ /* Vn is dummy and Vm is quanti */
                   7222:                      /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7223:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7224:                    }
                   7225:                  }else{ /* Vn*Vm Vn is quanti */
1.238     brouard  7226:                    if(DummyV[Tvard[ijp][2]]==0){
1.237     brouard  7227:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7228:                    }else{ /* Both quanti */
                   7229:                      fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7230:                    }
                   7231:                  }
1.238     brouard  7232:                  ijp++;
1.237     brouard  7233:                }
                   7234:              } else{  /* simple covariate */
                   7235:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(jk,j)]); /\* Valgrind bug nbcode *\/ */
                   7236:                if(Dummy[j]==0){
                   7237:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7238:                }else{ /* quantitative */
                   7239:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.223     brouard  7240:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7241:                }
1.237     brouard  7242:              } /* end simple */
                   7243:            } /* end j */
1.223     brouard  7244:          }else{
                   7245:            i=i-ncovmodel;
                   7246:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7247:              fprintf(ficgp," (1.");
                   7248:          }
1.227     brouard  7249:          
1.223     brouard  7250:          if(ng != 1){
                   7251:            fprintf(ficgp,")/(1");
1.227     brouard  7252:            
1.223     brouard  7253:            for(k1=1; k1 <=nlstate; k1++){ 
                   7254:              if(nagesqr==0)
                   7255:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                   7256:              else /* nagesqr =1 */
                   7257:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1,k3+(k1-1)*ncovmodel+1+nagesqr);
1.217     brouard  7258:               
1.223     brouard  7259:              ij=1;
                   7260:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.237     brouard  7261:                if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7262:                  if(ij <=cptcovage) { /* Bug valgrind */
1.223     brouard  7263:                    fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                   7264:                    /* fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7265:                    ij++;
                   7266:                  }
                   7267:                }
                   7268:                else
1.225     brouard  7269:                  fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7270:              }
                   7271:              fprintf(ficgp,")");
                   7272:            }
                   7273:            fprintf(ficgp,")");
                   7274:            if(ng ==2)
                   7275:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   7276:            else /* ng= 3 */
                   7277:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   7278:          }else{ /* end ng <> 1 */
                   7279:            if( k !=k2) /* logit p11 is hard to draw */
                   7280:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   7281:          }
                   7282:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7283:            fprintf(ficgp,",");
                   7284:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7285:            fprintf(ficgp,",");
                   7286:          i=i+ncovmodel;
                   7287:        } /* end k */
                   7288:       } /* end k2 */
                   7289:       fprintf(ficgp,"\n set out\n");
                   7290:     } /* end jk */
                   7291:   } /* end ng */
                   7292:   /* avoid: */
                   7293:   fflush(ficgp); 
1.126     brouard  7294: }  /* end gnuplot */
                   7295: 
                   7296: 
                   7297: /*************** Moving average **************/
1.219     brouard  7298: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  7299:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  7300:    
1.222     brouard  7301:    int i, cpt, cptcod;
                   7302:    int modcovmax =1;
                   7303:    int mobilavrange, mob;
                   7304:    int iage=0;
                   7305: 
                   7306:    double sum=0.;
                   7307:    double age;
                   7308:    double *sumnewp, *sumnewm;
                   7309:    double *agemingood, *agemaxgood; /* Currently identical for all covariates */
                   7310:   
                   7311:   
1.225     brouard  7312:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  7313:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   7314: 
                   7315:    sumnewp = vector(1,ncovcombmax);
                   7316:    sumnewm = vector(1,ncovcombmax);
                   7317:    agemingood = vector(1,ncovcombmax); 
                   7318:    agemaxgood = vector(1,ncovcombmax);
                   7319: 
                   7320:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7321:      sumnewm[cptcod]=0.;
                   7322:      sumnewp[cptcod]=0.;
                   7323:      agemingood[cptcod]=0;
                   7324:      agemaxgood[cptcod]=0;
                   7325:    }
                   7326:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   7327:   
                   7328:    if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   7329:      if(mobilav==1) mobilavrange=5; /* default */
                   7330:      else mobilavrange=mobilav;
                   7331:      for (age=bage; age<=fage; age++)
                   7332:        for (i=1; i<=nlstate;i++)
                   7333:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   7334:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   7335:      /* We keep the original values on the extreme ages bage, fage and for 
                   7336:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   7337:        we use a 5 terms etc. until the borders are no more concerned. 
                   7338:      */ 
                   7339:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   7340:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
                   7341:         for (i=1; i<=nlstate;i++){
                   7342:           for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7343:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   7344:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   7345:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   7346:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   7347:             }
                   7348:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
                   7349:           }
                   7350:         }
                   7351:        }/* end age */
                   7352:      }/* end mob */
                   7353:    }else
                   7354:      return -1;
                   7355:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7356:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7357:      if(invalidvarcomb[cptcod]){
                   7358:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7359:        continue;
                   7360:      }
1.219     brouard  7361: 
1.222     brouard  7362:      agemingood[cptcod]=fage-(mob-1)/2;
                   7363:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, finding the youngest wrong */
                   7364:        sumnewm[cptcod]=0.;
                   7365:        for (i=1; i<=nlstate;i++){
                   7366:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7367:        }
                   7368:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7369:         agemingood[cptcod]=age;
                   7370:        }else{ /* bad */
                   7371:         for (i=1; i<=nlstate;i++){
                   7372:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7373:         } /* i */
                   7374:        } /* end bad */
                   7375:      }/* age */
                   7376:      sum=0.;
                   7377:      for (i=1; i<=nlstate;i++){
                   7378:        sum+=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7379:      }
                   7380:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7381:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any descending age!\n",cptcod);
                   7382:        /* for (i=1; i<=nlstate;i++){ */
                   7383:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7384:        /* } /\* i *\/ */
                   7385:      } /* end bad */
                   7386:      /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   7387:      /* From youngest, finding the oldest wrong */
                   7388:      agemaxgood[cptcod]=bage+(mob-1)/2;
                   7389:      for (age=bage+(mob-1)/2; age<=fage; age++){
                   7390:        sumnewm[cptcod]=0.;
                   7391:        for (i=1; i<=nlstate;i++){
                   7392:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7393:        }
                   7394:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7395:         agemaxgood[cptcod]=age;
                   7396:        }else{ /* bad */
                   7397:         for (i=1; i<=nlstate;i++){
                   7398:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7399:         } /* i */
                   7400:        } /* end bad */
                   7401:      }/* age */
                   7402:      sum=0.;
                   7403:      for (i=1; i<=nlstate;i++){
                   7404:        sum+=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7405:      }
                   7406:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7407:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any ascending age!\n",cptcod);
                   7408:        /* for (i=1; i<=nlstate;i++){ */
                   7409:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7410:        /* } /\* i *\/ */
                   7411:      } /* end bad */
                   7412:                
                   7413:      for (age=bage; age<=fage; age++){
1.235     brouard  7414:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  7415:        sumnewp[cptcod]=0.;
                   7416:        sumnewm[cptcod]=0.;
                   7417:        for (i=1; i<=nlstate;i++){
                   7418:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   7419:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7420:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   7421:        }
                   7422:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   7423:      }
                   7424:      /* printf("\n"); */
                   7425:      /* } */
                   7426:      /* brutal averaging */
                   7427:      for (i=1; i<=nlstate;i++){
                   7428:        for (age=1; age<=bage; age++){
                   7429:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7430:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7431:        }       
                   7432:        for (age=fage; age<=AGESUP; age++){
                   7433:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7434:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7435:        }
                   7436:      } /* end i status */
                   7437:      for (i=nlstate+1; i<=nlstate+ndeath;i++){
                   7438:        for (age=1; age<=AGESUP; age++){
                   7439:         /*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*/
                   7440:         mobaverage[(int)age][i][cptcod]=0.;
                   7441:        }
                   7442:      }
                   7443:    }/* end cptcod */
                   7444:    free_vector(sumnewm,1, ncovcombmax);
                   7445:    free_vector(sumnewp,1, ncovcombmax);
                   7446:    free_vector(agemaxgood,1, ncovcombmax);
                   7447:    free_vector(agemingood,1, ncovcombmax);
                   7448:    return 0;
                   7449:  }/* End movingaverage */
1.218     brouard  7450:  
1.126     brouard  7451: 
                   7452: /************** Forecasting ******************/
1.235     brouard  7453:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  7454:   /* proj1, year, month, day of starting projection 
                   7455:      agemin, agemax range of age
                   7456:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   7457:      anproj2 year of en of projection (same day and month as proj1).
                   7458:   */
1.235     brouard  7459:    int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  7460:   double agec; /* generic age */
                   7461:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   7462:   double *popeffectif,*popcount;
                   7463:   double ***p3mat;
1.218     brouard  7464:   /* double ***mobaverage; */
1.126     brouard  7465:   char fileresf[FILENAMELENGTH];
                   7466: 
                   7467:   agelim=AGESUP;
1.211     brouard  7468:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   7469:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   7470:      We still use firstpass and lastpass as another selection.
                   7471:   */
1.214     brouard  7472:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   7473:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  7474:  
1.201     brouard  7475:   strcpy(fileresf,"F_"); 
                   7476:   strcat(fileresf,fileresu);
1.126     brouard  7477:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   7478:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   7479:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   7480:   }
1.235     brouard  7481:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   7482:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  7483: 
1.225     brouard  7484:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  7485: 
                   7486: 
                   7487:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   7488:   if (stepm<=12) stepsize=1;
                   7489:   if(estepm < stepm){
                   7490:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   7491:   }
                   7492:   else  hstepm=estepm;   
                   7493: 
                   7494:   hstepm=hstepm/stepm; 
                   7495:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   7496:                                fractional in yp1 */
                   7497:   anprojmean=yp;
                   7498:   yp2=modf((yp1*12),&yp);
                   7499:   mprojmean=yp;
                   7500:   yp1=modf((yp2*30.5),&yp);
                   7501:   jprojmean=yp;
                   7502:   if(jprojmean==0) jprojmean=1;
                   7503:   if(mprojmean==0) jprojmean=1;
                   7504: 
1.227     brouard  7505:   i1=pow(2,cptcoveff);
1.126     brouard  7506:   if (cptcovn < 1){i1=1;}
                   7507:   
                   7508:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   7509:   
                   7510:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  7511:   
1.126     brouard  7512: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  7513:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7514:   for(k=1; k<=i1;k++){
1.253   ! brouard  7515:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  7516:       continue;
1.227     brouard  7517:     if(invalidvarcomb[k]){
                   7518:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   7519:       continue;
                   7520:     }
                   7521:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   7522:     for(j=1;j<=cptcoveff;j++) {
                   7523:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7524:     }
1.235     brouard  7525:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7526:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  7527:     }
1.227     brouard  7528:     fprintf(ficresf," yearproj age");
                   7529:     for(j=1; j<=nlstate+ndeath;j++){ 
                   7530:       for(i=1; i<=nlstate;i++)               
                   7531:        fprintf(ficresf," p%d%d",i,j);
                   7532:       fprintf(ficresf," wp.%d",j);
                   7533:     }
                   7534:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   7535:       fprintf(ficresf,"\n");
                   7536:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
                   7537:       for (agec=fage; agec>=(ageminpar-1); agec--){ 
                   7538:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   7539:        nhstepm = nhstepm/hstepm; 
                   7540:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7541:        oldm=oldms;savm=savms;
1.235     brouard  7542:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.227     brouard  7543:        
                   7544:        for (h=0; h<=nhstepm; h++){
                   7545:          if (h*hstepm/YEARM*stepm ==yearp) {
                   7546:            fprintf(ficresf,"\n");
                   7547:            for(j=1;j<=cptcoveff;j++) 
                   7548:              fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7549:            fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   7550:          } 
                   7551:          for(j=1; j<=nlstate+ndeath;j++) {
                   7552:            ppij=0.;
                   7553:            for(i=1; i<=nlstate;i++) {
                   7554:              if (mobilav==1) 
                   7555:                ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][k];
                   7556:              else {
                   7557:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   7558:              }
                   7559:              if (h*hstepm/YEARM*stepm== yearp) {
                   7560:                fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   7561:              }
                   7562:            } /* end i */
                   7563:            if (h*hstepm/YEARM*stepm==yearp) {
                   7564:              fprintf(ficresf," %.3f", ppij);
                   7565:            }
                   7566:          }/* end j */
                   7567:        } /* end h */
                   7568:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7569:       } /* end agec */
                   7570:     } /* end yearp */
                   7571:   } /* end  k */
1.219     brouard  7572:        
1.126     brouard  7573:   fclose(ficresf);
1.215     brouard  7574:   printf("End of Computing forecasting \n");
                   7575:   fprintf(ficlog,"End of Computing forecasting\n");
                   7576: 
1.126     brouard  7577: }
                   7578: 
1.218     brouard  7579: /* /\************** Back Forecasting ******************\/ */
1.225     brouard  7580: /* void prevbackforecast(char fileres[], double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
1.218     brouard  7581: /*   /\* back1, year, month, day of starting backection  */
                   7582: /*      agemin, agemax range of age */
                   7583: /*      dateprev1 dateprev2 range of dates during which prevalence is computed */
                   7584: /*      anback2 year of en of backection (same day and month as back1). */
                   7585: /*   *\/ */
                   7586: /*   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1; */
                   7587: /*   double agec; /\* generic age *\/ */
                   7588: /*   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean; */
                   7589: /*   double *popeffectif,*popcount; */
                   7590: /*   double ***p3mat; */
                   7591: /*   /\* double ***mobaverage; *\/ */
                   7592: /*   char fileresfb[FILENAMELENGTH]; */
                   7593:        
                   7594: /*   agelim=AGESUP; */
                   7595: /*   /\* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people */
                   7596: /*      in each health status at the date of interview (if between dateprev1 and dateprev2). */
                   7597: /*      We still use firstpass and lastpass as another selection. */
                   7598: /*   *\/ */
                   7599: /*   /\* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ *\/ */
                   7600: /*   /\*             firstpass, lastpass,  stepm,  weightopt, model); *\/ */
                   7601: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   7602:        
                   7603: /*   strcpy(fileresfb,"FB_");  */
                   7604: /*   strcat(fileresfb,fileresu); */
                   7605: /*   if((ficresfb=fopen(fileresfb,"w"))==NULL) { */
                   7606: /*     printf("Problem with back forecast resultfile: %s\n", fileresfb); */
                   7607: /*     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb); */
                   7608: /*   } */
                   7609: /*   printf("Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7610: /*   fprintf(ficlog,"Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7611:        
1.225     brouard  7612: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.218     brouard  7613:        
                   7614: /*   /\* if (mobilav!=0) { *\/ */
                   7615: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7616: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7617: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7618: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7619: /*   /\*   } *\/ */
                   7620: /*   /\* } *\/ */
                   7621:        
                   7622: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7623: /*   if (stepm<=12) stepsize=1; */
                   7624: /*   if(estepm < stepm){ */
                   7625: /*     printf ("Problem %d lower than %d\n",estepm, stepm); */
                   7626: /*   } */
                   7627: /*   else  hstepm=estepm;    */
                   7628:        
                   7629: /*   hstepm=hstepm/stepm;  */
                   7630: /*   yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   7631: /*                                fractional in yp1 *\/ */
                   7632: /*   anprojmean=yp; */
                   7633: /*   yp2=modf((yp1*12),&yp); */
                   7634: /*   mprojmean=yp; */
                   7635: /*   yp1=modf((yp2*30.5),&yp); */
                   7636: /*   jprojmean=yp; */
                   7637: /*   if(jprojmean==0) jprojmean=1; */
                   7638: /*   if(mprojmean==0) jprojmean=1; */
                   7639:        
1.225     brouard  7640: /*   i1=cptcoveff; */
1.218     brouard  7641: /*   if (cptcovn < 1){i1=1;} */
1.217     brouard  7642:   
1.218     brouard  7643: /*   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);  */
1.217     brouard  7644:   
1.218     brouard  7645: /*   fprintf(ficresfb,"#****** Routine prevbackforecast **\n"); */
                   7646:        
                   7647: /*     /\*           if (h==(int)(YEARM*yearp)){ *\/ */
                   7648: /*   for(cptcov=1, k=0;cptcov<=i1;cptcov++){ */
1.225     brouard  7649: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
1.218     brouard  7650: /*       k=k+1; */
                   7651: /*       fprintf(ficresfb,"\n#****** hbijx=probability over h years, hp.jx is weighted by observed prev \n#"); */
1.225     brouard  7652: /*       for(j=1;j<=cptcoveff;j++) { */
1.218     brouard  7653: /*                             fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7654: /*       } */
                   7655: /*       fprintf(ficresfb," yearbproj age"); */
                   7656: /*       for(j=1; j<=nlstate+ndeath;j++){  */
                   7657: /*                             for(i=1; i<=nlstate;i++)               */
                   7658: /*           fprintf(ficresfb," p%d%d",i,j); */
                   7659: /*                             fprintf(ficresfb," p.%d",j); */
                   7660: /*       } */
                   7661: /*       for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {  */
                   7662: /*                             /\* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  *\/ */
                   7663: /*                             fprintf(ficresfb,"\n"); */
                   7664: /*                             fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);    */
                   7665: /*                             for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   7666: /*                                     nhstepm=(int) rint((agelim-agec)*YEARM/stepm);  */
                   7667: /*                                     nhstepm = nhstepm/hstepm;  */
                   7668: /*                                     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7669: /*                                     oldm=oldms;savm=savms; */
                   7670: /*                                     hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm,oldm,savm, dnewm, doldm, dsavm, k);       */
                   7671: /*                                     for (h=0; h<=nhstepm; h++){ */
                   7672: /*                                             if (h*hstepm/YEARM*stepm ==yearp) { */
                   7673: /*               fprintf(ficresfb,"\n"); */
1.225     brouard  7674: /*               for(j=1;j<=cptcoveff;j++)  */
1.218     brouard  7675: /*                 fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7676: /*                                                     fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec+h*hstepm/YEARM*stepm); */
                   7677: /*                                             }  */
                   7678: /*                                             for(j=1; j<=nlstate+ndeath;j++) { */
                   7679: /*                                                     ppij=0.; */
                   7680: /*                                                     for(i=1; i<=nlstate;i++) { */
                   7681: /*                                                             if (mobilav==1)  */
                   7682: /*                                                                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod]; */
                   7683: /*                                                             else { */
                   7684: /*                                                                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod]; */
                   7685: /*                                                             } */
                   7686: /*                                                             if (h*hstepm/YEARM*stepm== yearp) { */
                   7687: /*                                                                     fprintf(ficresfb," %.3f", p3mat[i][j][h]); */
                   7688: /*                                                             } */
                   7689: /*                                                     } /\* end i *\/ */
                   7690: /*                                                     if (h*hstepm/YEARM*stepm==yearp) { */
                   7691: /*                                                             fprintf(ficresfb," %.3f", ppij); */
                   7692: /*                                                     } */
                   7693: /*                                             }/\* end j *\/ */
                   7694: /*                                     } /\* end h *\/ */
                   7695: /*                                     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7696: /*                             } /\* end agec *\/ */
                   7697: /*       } /\* end yearp *\/ */
                   7698: /*     } /\* end cptcod *\/ */
                   7699: /*   } /\* end  cptcov *\/ */
                   7700:        
                   7701: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7702:        
                   7703: /*   fclose(ficresfb); */
                   7704: /*   printf("End of Computing Back forecasting \n"); */
                   7705: /*   fprintf(ficlog,"End of Computing Back forecasting\n"); */
1.217     brouard  7706:        
1.218     brouard  7707: /* } */
1.217     brouard  7708: 
1.126     brouard  7709: /************** Forecasting *****not tested NB*************/
1.227     brouard  7710: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  7711:   
1.227     brouard  7712: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   7713: /*   int *popage; */
                   7714: /*   double calagedatem, agelim, kk1, kk2; */
                   7715: /*   double *popeffectif,*popcount; */
                   7716: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   7717: /*   /\* double ***mobaverage; *\/ */
                   7718: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  7719: 
1.227     brouard  7720: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7721: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7722: /*   agelim=AGESUP; */
                   7723: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  7724:   
1.227     brouard  7725: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  7726:   
                   7727:   
1.227     brouard  7728: /*   strcpy(filerespop,"POP_");  */
                   7729: /*   strcat(filerespop,fileresu); */
                   7730: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   7731: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   7732: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   7733: /*   } */
                   7734: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   7735: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  7736: 
1.227     brouard  7737: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  7738: 
1.227     brouard  7739: /*   /\* if (mobilav!=0) { *\/ */
                   7740: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7741: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7742: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7743: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7744: /*   /\*   } *\/ */
                   7745: /*   /\* } *\/ */
1.126     brouard  7746: 
1.227     brouard  7747: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7748: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  7749:   
1.227     brouard  7750: /*   agelim=AGESUP; */
1.126     brouard  7751:   
1.227     brouard  7752: /*   hstepm=1; */
                   7753: /*   hstepm=hstepm/stepm;  */
1.218     brouard  7754:        
1.227     brouard  7755: /*   if (popforecast==1) { */
                   7756: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   7757: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   7758: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   7759: /*     }  */
                   7760: /*     popage=ivector(0,AGESUP); */
                   7761: /*     popeffectif=vector(0,AGESUP); */
                   7762: /*     popcount=vector(0,AGESUP); */
1.126     brouard  7763:     
1.227     brouard  7764: /*     i=1;    */
                   7765: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  7766:     
1.227     brouard  7767: /*     imx=i; */
                   7768: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   7769: /*   } */
1.218     brouard  7770:   
1.227     brouard  7771: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   7772: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   7773: /*       k=k+1; */
                   7774: /*       fprintf(ficrespop,"\n#******"); */
                   7775: /*       for(j=1;j<=cptcoveff;j++) { */
                   7776: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7777: /*       } */
                   7778: /*       fprintf(ficrespop,"******\n"); */
                   7779: /*       fprintf(ficrespop,"# Age"); */
                   7780: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   7781: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  7782:       
1.227     brouard  7783: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   7784: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  7785:        
1.227     brouard  7786: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7787: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7788: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7789:          
1.227     brouard  7790: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7791: /*       oldm=oldms;savm=savms; */
                   7792: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  7793:          
1.227     brouard  7794: /*       for (h=0; h<=nhstepm; h++){ */
                   7795: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7796: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7797: /*         }  */
                   7798: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7799: /*           kk1=0.;kk2=0; */
                   7800: /*           for(i=1; i<=nlstate;i++) {               */
                   7801: /*             if (mobilav==1)  */
                   7802: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   7803: /*             else { */
                   7804: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   7805: /*             } */
                   7806: /*           } */
                   7807: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   7808: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   7809: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   7810: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   7811: /*           } */
                   7812: /*         } */
                   7813: /*         for(i=1; i<=nlstate;i++){ */
                   7814: /*           kk1=0.; */
                   7815: /*           for(j=1; j<=nlstate;j++){ */
                   7816: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   7817: /*           } */
                   7818: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   7819: /*         } */
1.218     brouard  7820:            
1.227     brouard  7821: /*         if (h==(int)(calagedatem+12*cpt)) */
                   7822: /*           for(j=1; j<=nlstate;j++)  */
                   7823: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   7824: /*       } */
                   7825: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7826: /*     } */
                   7827: /*       } */
1.218     brouard  7828:       
1.227     brouard  7829: /*       /\******\/ */
1.218     brouard  7830:       
1.227     brouard  7831: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   7832: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   7833: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7834: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7835: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7836:          
1.227     brouard  7837: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7838: /*       oldm=oldms;savm=savms; */
                   7839: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   7840: /*       for (h=0; h<=nhstepm; h++){ */
                   7841: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7842: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7843: /*         }  */
                   7844: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7845: /*           kk1=0.;kk2=0; */
                   7846: /*           for(i=1; i<=nlstate;i++) {               */
                   7847: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   7848: /*           } */
                   7849: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   7850: /*         } */
                   7851: /*       } */
                   7852: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7853: /*     } */
                   7854: /*       } */
                   7855: /*     }  */
                   7856: /*   } */
1.218     brouard  7857:   
1.227     brouard  7858: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  7859:   
1.227     brouard  7860: /*   if (popforecast==1) { */
                   7861: /*     free_ivector(popage,0,AGESUP); */
                   7862: /*     free_vector(popeffectif,0,AGESUP); */
                   7863: /*     free_vector(popcount,0,AGESUP); */
                   7864: /*   } */
                   7865: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7866: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7867: /*   fclose(ficrespop); */
                   7868: /* } /\* End of popforecast *\/ */
1.218     brouard  7869:  
1.126     brouard  7870: int fileappend(FILE *fichier, char *optionfich)
                   7871: {
                   7872:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   7873:     printf("Problem with file: %s\n", optionfich);
                   7874:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   7875:     return (0);
                   7876:   }
                   7877:   fflush(fichier);
                   7878:   return (1);
                   7879: }
                   7880: 
                   7881: 
                   7882: /**************** function prwizard **********************/
                   7883: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   7884: {
                   7885: 
                   7886:   /* Wizard to print covariance matrix template */
                   7887: 
1.164     brouard  7888:   char ca[32], cb[32];
                   7889:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  7890:   int numlinepar;
                   7891: 
                   7892:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7893:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7894:   for(i=1; i <=nlstate; i++){
                   7895:     jj=0;
                   7896:     for(j=1; j <=nlstate+ndeath; j++){
                   7897:       if(j==i) continue;
                   7898:       jj++;
                   7899:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   7900:       printf("%1d%1d",i,j);
                   7901:       fprintf(ficparo,"%1d%1d",i,j);
                   7902:       for(k=1; k<=ncovmodel;k++){
                   7903:        /*        printf(" %lf",param[i][j][k]); */
                   7904:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   7905:        printf(" 0.");
                   7906:        fprintf(ficparo," 0.");
                   7907:       }
                   7908:       printf("\n");
                   7909:       fprintf(ficparo,"\n");
                   7910:     }
                   7911:   }
                   7912:   printf("# Scales (for hessian or gradient estimation)\n");
                   7913:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   7914:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   7915:   for(i=1; i <=nlstate; i++){
                   7916:     jj=0;
                   7917:     for(j=1; j <=nlstate+ndeath; j++){
                   7918:       if(j==i) continue;
                   7919:       jj++;
                   7920:       fprintf(ficparo,"%1d%1d",i,j);
                   7921:       printf("%1d%1d",i,j);
                   7922:       fflush(stdout);
                   7923:       for(k=1; k<=ncovmodel;k++){
                   7924:        /*      printf(" %le",delti3[i][j][k]); */
                   7925:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   7926:        printf(" 0.");
                   7927:        fprintf(ficparo," 0.");
                   7928:       }
                   7929:       numlinepar++;
                   7930:       printf("\n");
                   7931:       fprintf(ficparo,"\n");
                   7932:     }
                   7933:   }
                   7934:   printf("# Covariance matrix\n");
                   7935: /* # 121 Var(a12)\n\ */
                   7936: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7937: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   7938: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   7939: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   7940: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   7941: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   7942: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   7943:   fflush(stdout);
                   7944:   fprintf(ficparo,"# Covariance matrix\n");
                   7945:   /* # 121 Var(a12)\n\ */
                   7946:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7947:   /* #   ...\n\ */
                   7948:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   7949:   
                   7950:   for(itimes=1;itimes<=2;itimes++){
                   7951:     jj=0;
                   7952:     for(i=1; i <=nlstate; i++){
                   7953:       for(j=1; j <=nlstate+ndeath; j++){
                   7954:        if(j==i) continue;
                   7955:        for(k=1; k<=ncovmodel;k++){
                   7956:          jj++;
                   7957:          ca[0]= k+'a'-1;ca[1]='\0';
                   7958:          if(itimes==1){
                   7959:            printf("#%1d%1d%d",i,j,k);
                   7960:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   7961:          }else{
                   7962:            printf("%1d%1d%d",i,j,k);
                   7963:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   7964:            /*  printf(" %.5le",matcov[i][j]); */
                   7965:          }
                   7966:          ll=0;
                   7967:          for(li=1;li <=nlstate; li++){
                   7968:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   7969:              if(lj==li) continue;
                   7970:              for(lk=1;lk<=ncovmodel;lk++){
                   7971:                ll++;
                   7972:                if(ll<=jj){
                   7973:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   7974:                  if(ll<jj){
                   7975:                    if(itimes==1){
                   7976:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7977:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7978:                    }else{
                   7979:                      printf(" 0.");
                   7980:                      fprintf(ficparo," 0.");
                   7981:                    }
                   7982:                  }else{
                   7983:                    if(itimes==1){
                   7984:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   7985:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   7986:                    }else{
                   7987:                      printf(" 0.");
                   7988:                      fprintf(ficparo," 0.");
                   7989:                    }
                   7990:                  }
                   7991:                }
                   7992:              } /* end lk */
                   7993:            } /* end lj */
                   7994:          } /* end li */
                   7995:          printf("\n");
                   7996:          fprintf(ficparo,"\n");
                   7997:          numlinepar++;
                   7998:        } /* end k*/
                   7999:       } /*end j */
                   8000:     } /* end i */
                   8001:   } /* end itimes */
                   8002: 
                   8003: } /* end of prwizard */
                   8004: /******************* Gompertz Likelihood ******************************/
                   8005: double gompertz(double x[])
                   8006: { 
                   8007:   double A,B,L=0.0,sump=0.,num=0.;
                   8008:   int i,n=0; /* n is the size of the sample */
                   8009: 
1.220     brouard  8010:   for (i=1;i<=imx ; i++) {
1.126     brouard  8011:     sump=sump+weight[i];
                   8012:     /*    sump=sump+1;*/
                   8013:     num=num+1;
                   8014:   }
                   8015:  
                   8016:  
                   8017:   /* for (i=0; i<=imx; i++) 
                   8018:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8019: 
                   8020:   for (i=1;i<=imx ; i++)
                   8021:     {
                   8022:       if (cens[i] == 1 && wav[i]>1)
                   8023:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8024:       
                   8025:       if (cens[i] == 0 && wav[i]>1)
                   8026:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8027:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8028:       
                   8029:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8030:       if (wav[i] > 1 ) { /* ??? */
                   8031:        L=L+A*weight[i];
                   8032:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8033:       }
                   8034:     }
                   8035: 
                   8036:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8037:  
                   8038:   return -2*L*num/sump;
                   8039: }
                   8040: 
1.136     brouard  8041: #ifdef GSL
                   8042: /******************* Gompertz_f Likelihood ******************************/
                   8043: double gompertz_f(const gsl_vector *v, void *params)
                   8044: { 
                   8045:   double A,B,LL=0.0,sump=0.,num=0.;
                   8046:   double *x= (double *) v->data;
                   8047:   int i,n=0; /* n is the size of the sample */
                   8048: 
                   8049:   for (i=0;i<=imx-1 ; i++) {
                   8050:     sump=sump+weight[i];
                   8051:     /*    sump=sump+1;*/
                   8052:     num=num+1;
                   8053:   }
                   8054:  
                   8055:  
                   8056:   /* for (i=0; i<=imx; i++) 
                   8057:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8058:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   8059:   for (i=1;i<=imx ; i++)
                   8060:     {
                   8061:       if (cens[i] == 1 && wav[i]>1)
                   8062:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   8063:       
                   8064:       if (cens[i] == 0 && wav[i]>1)
                   8065:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   8066:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   8067:       
                   8068:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8069:       if (wav[i] > 1 ) { /* ??? */
                   8070:        LL=LL+A*weight[i];
                   8071:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8072:       }
                   8073:     }
                   8074: 
                   8075:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8076:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   8077:  
                   8078:   return -2*LL*num/sump;
                   8079: }
                   8080: #endif
                   8081: 
1.126     brouard  8082: /******************* Printing html file ***********/
1.201     brouard  8083: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  8084:                  int lastpass, int stepm, int weightopt, char model[],\
                   8085:                  int imx,  double p[],double **matcov,double agemortsup){
                   8086:   int i,k;
                   8087: 
                   8088:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   8089:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   8090:   for (i=1;i<=2;i++) 
                   8091:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  8092:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  8093:   fprintf(fichtm,"</ul>");
                   8094: 
                   8095: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   8096: 
                   8097:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   8098: 
                   8099:  for (k=agegomp;k<(agemortsup-2);k++) 
                   8100:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   8101: 
                   8102:  
                   8103:   fflush(fichtm);
                   8104: }
                   8105: 
                   8106: /******************* Gnuplot file **************/
1.201     brouard  8107: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  8108: 
                   8109:   char dirfileres[132],optfileres[132];
1.164     brouard  8110: 
1.126     brouard  8111:   int ng;
                   8112: 
                   8113: 
                   8114:   /*#ifdef windows */
                   8115:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   8116:     /*#endif */
                   8117: 
                   8118: 
                   8119:   strcpy(dirfileres,optionfilefiname);
                   8120:   strcpy(optfileres,"vpl");
1.199     brouard  8121:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  8122:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  8123:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  8124:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  8125:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   8126: 
                   8127: } 
                   8128: 
1.136     brouard  8129: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   8130: {
1.126     brouard  8131: 
1.136     brouard  8132:   /*-------- data file ----------*/
                   8133:   FILE *fic;
                   8134:   char dummy[]="                         ";
1.240     brouard  8135:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  8136:   int lstra;
1.136     brouard  8137:   int linei, month, year,iout;
                   8138:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  8139:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  8140:   char *stratrunc;
1.223     brouard  8141: 
1.240     brouard  8142:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   8143:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  8144: 
1.240     brouard  8145:   for(v=1; v <=ncovcol;v++){
                   8146:     DummyV[v]=0;
                   8147:     FixedV[v]=0;
                   8148:   }
                   8149:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   8150:     DummyV[v]=1;
                   8151:     FixedV[v]=0;
                   8152:   }
                   8153:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   8154:     DummyV[v]=0;
                   8155:     FixedV[v]=1;
                   8156:   }
                   8157:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8158:     DummyV[v]=1;
                   8159:     FixedV[v]=1;
                   8160:   }
                   8161:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8162:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8163:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8164:   }
1.126     brouard  8165: 
1.136     brouard  8166:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  8167:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   8168:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  8169:   }
1.126     brouard  8170: 
1.136     brouard  8171:   i=1;
                   8172:   linei=0;
                   8173:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   8174:     linei=linei+1;
                   8175:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   8176:       if(line[j] == '\t')
                   8177:        line[j] = ' ';
                   8178:     }
                   8179:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   8180:       ;
                   8181:     };
                   8182:     line[j+1]=0;  /* Trims blanks at end of line */
                   8183:     if(line[0]=='#'){
                   8184:       fprintf(ficlog,"Comment line\n%s\n",line);
                   8185:       printf("Comment line\n%s\n",line);
                   8186:       continue;
                   8187:     }
                   8188:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  8189:     strcpy(line, linetmp);
1.223     brouard  8190:     
                   8191:     /* Loops on waves */
                   8192:     for (j=maxwav;j>=1;j--){
                   8193:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  8194:        cutv(stra, strb, line, ' '); 
                   8195:        if(strb[0]=='.') { /* Missing value */
                   8196:          lval=-1;
                   8197:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   8198:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   8199:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   8200:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   8201:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   8202:            return 1;
                   8203:          }
                   8204:        }else{
                   8205:          errno=0;
                   8206:          /* what_kind_of_number(strb); */
                   8207:          dval=strtod(strb,&endptr); 
                   8208:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   8209:          /* if(strb != endptr && *endptr == '\0') */
                   8210:          /*    dval=dlval; */
                   8211:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8212:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8213:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   8214:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   8215:            return 1;
                   8216:          }
                   8217:          cotqvar[j][iv][i]=dval; 
                   8218:          cotvar[j][ntv+iv][i]=dval; 
                   8219:        }
                   8220:        strcpy(line,stra);
1.223     brouard  8221:       }/* end loop ntqv */
1.225     brouard  8222:       
1.223     brouard  8223:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  8224:        cutv(stra, strb, line, ' '); 
                   8225:        if(strb[0]=='.') { /* Missing value */
                   8226:          lval=-1;
                   8227:        }else{
                   8228:          errno=0;
                   8229:          lval=strtol(strb,&endptr,10); 
                   8230:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8231:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8232:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   8233:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   8234:            return 1;
                   8235:          }
                   8236:        }
                   8237:        if(lval <-1 || lval >1){
                   8238:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8239:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8240:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8241:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8242:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8243:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8244:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8245:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8246:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  8247:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8248:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8249:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8250:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8251:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8252:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8253:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8254:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8255:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  8256:          return 1;
                   8257:        }
                   8258:        cotvar[j][iv][i]=(double)(lval);
                   8259:        strcpy(line,stra);
1.223     brouard  8260:       }/* end loop ntv */
1.225     brouard  8261:       
1.223     brouard  8262:       /* Statuses  at wave */
1.137     brouard  8263:       cutv(stra, strb, line, ' '); 
1.223     brouard  8264:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  8265:        lval=-1;
1.136     brouard  8266:       }else{
1.238     brouard  8267:        errno=0;
                   8268:        lval=strtol(strb,&endptr,10); 
                   8269:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8270:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8271:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   8272:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   8273:          return 1;
                   8274:        }
1.136     brouard  8275:       }
1.225     brouard  8276:       
1.136     brouard  8277:       s[j][i]=lval;
1.225     brouard  8278:       
1.223     brouard  8279:       /* Date of Interview */
1.136     brouard  8280:       strcpy(line,stra);
                   8281:       cutv(stra, strb,line,' ');
1.169     brouard  8282:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8283:       }
1.169     brouard  8284:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  8285:        month=99;
                   8286:        year=9999;
1.136     brouard  8287:       }else{
1.225     brouard  8288:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   8289:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   8290:        return 1;
1.136     brouard  8291:       }
                   8292:       anint[j][i]= (double) year; 
                   8293:       mint[j][i]= (double)month; 
                   8294:       strcpy(line,stra);
1.223     brouard  8295:     } /* End loop on waves */
1.225     brouard  8296:     
1.223     brouard  8297:     /* Date of death */
1.136     brouard  8298:     cutv(stra, strb,line,' '); 
1.169     brouard  8299:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8300:     }
1.169     brouard  8301:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  8302:       month=99;
                   8303:       year=9999;
                   8304:     }else{
1.141     brouard  8305:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  8306:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   8307:       return 1;
1.136     brouard  8308:     }
                   8309:     andc[i]=(double) year; 
                   8310:     moisdc[i]=(double) month; 
                   8311:     strcpy(line,stra);
                   8312:     
1.223     brouard  8313:     /* Date of birth */
1.136     brouard  8314:     cutv(stra, strb,line,' '); 
1.169     brouard  8315:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8316:     }
1.169     brouard  8317:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  8318:       month=99;
                   8319:       year=9999;
                   8320:     }else{
1.141     brouard  8321:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   8322:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8323:       return 1;
1.136     brouard  8324:     }
                   8325:     if (year==9999) {
1.141     brouard  8326:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   8327:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8328:       return 1;
                   8329:       
1.136     brouard  8330:     }
                   8331:     annais[i]=(double)(year);
                   8332:     moisnais[i]=(double)(month); 
                   8333:     strcpy(line,stra);
1.225     brouard  8334:     
1.223     brouard  8335:     /* Sample weight */
1.136     brouard  8336:     cutv(stra, strb,line,' '); 
                   8337:     errno=0;
                   8338:     dval=strtod(strb,&endptr); 
                   8339:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  8340:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   8341:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  8342:       fflush(ficlog);
                   8343:       return 1;
                   8344:     }
                   8345:     weight[i]=dval; 
                   8346:     strcpy(line,stra);
1.225     brouard  8347:     
1.223     brouard  8348:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   8349:       cutv(stra, strb, line, ' '); 
                   8350:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  8351:        lval=-1;
1.223     brouard  8352:       }else{
1.225     brouard  8353:        errno=0;
                   8354:        /* what_kind_of_number(strb); */
                   8355:        dval=strtod(strb,&endptr);
                   8356:        /* if(strb != endptr && *endptr == '\0') */
                   8357:        /*   dval=dlval; */
                   8358:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8359:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8360:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   8361:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   8362:          return 1;
                   8363:        }
                   8364:        coqvar[iv][i]=dval; 
1.226     brouard  8365:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  8366:       }
                   8367:       strcpy(line,stra);
                   8368:     }/* end loop nqv */
1.136     brouard  8369:     
1.223     brouard  8370:     /* Covariate values */
1.136     brouard  8371:     for (j=ncovcol;j>=1;j--){
                   8372:       cutv(stra, strb,line,' '); 
1.223     brouard  8373:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  8374:        lval=-1;
1.136     brouard  8375:       }else{
1.225     brouard  8376:        errno=0;
                   8377:        lval=strtol(strb,&endptr,10); 
                   8378:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8379:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   8380:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   8381:          return 1;
                   8382:        }
1.136     brouard  8383:       }
                   8384:       if(lval <-1 || lval >1){
1.225     brouard  8385:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8386:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8387:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8388:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8389:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8390:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8391:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8392:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8393:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  8394:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8395:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8396:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8397:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8398:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8399:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8400:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8401:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8402:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  8403:        return 1;
1.136     brouard  8404:       }
                   8405:       covar[j][i]=(double)(lval);
                   8406:       strcpy(line,stra);
                   8407:     }  
                   8408:     lstra=strlen(stra);
1.225     brouard  8409:     
1.136     brouard  8410:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   8411:       stratrunc = &(stra[lstra-9]);
                   8412:       num[i]=atol(stratrunc);
                   8413:     }
                   8414:     else
                   8415:       num[i]=atol(stra);
                   8416:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   8417:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   8418:     
                   8419:     i=i+1;
                   8420:   } /* End loop reading  data */
1.225     brouard  8421:   
1.136     brouard  8422:   *imax=i-1; /* Number of individuals */
                   8423:   fclose(fic);
1.225     brouard  8424:   
1.136     brouard  8425:   return (0);
1.164     brouard  8426:   /* endread: */
1.225     brouard  8427:   printf("Exiting readdata: ");
                   8428:   fclose(fic);
                   8429:   return (1);
1.223     brouard  8430: }
1.126     brouard  8431: 
1.234     brouard  8432: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  8433:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  8434:   while (*p2 == ' ')
1.234     brouard  8435:     p2++; 
                   8436:   /* while ((*p1++ = *p2++) !=0) */
                   8437:   /*   ; */
                   8438:   /* do */
                   8439:   /*   while (*p2 == ' ') */
                   8440:   /*     p2++; */
                   8441:   /* while (*p1++ == *p2++); */
                   8442:   *stri=p2; 
1.145     brouard  8443: }
                   8444: 
1.235     brouard  8445: int decoderesult ( char resultline[], int nres)
1.230     brouard  8446: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   8447: {
1.235     brouard  8448:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  8449:   char resultsav[MAXLINE];
1.234     brouard  8450:   int resultmodel[MAXLINE];
                   8451:   int modelresult[MAXLINE];
1.230     brouard  8452:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   8453: 
1.234     brouard  8454:   removefirstspace(&resultline);
1.233     brouard  8455:   printf("decoderesult:%s\n",resultline);
1.230     brouard  8456: 
                   8457:   if (strstr(resultline,"v") !=0){
                   8458:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   8459:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   8460:     return 1;
                   8461:   }
                   8462:   trimbb(resultsav, resultline);
                   8463:   if (strlen(resultsav) >1){
                   8464:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   8465:   }
1.253   ! brouard  8466:   if(j == 0){ /* Resultline but no = */
        !          8467:     TKresult[nres]=0; /* Combination for the nresult and the model */
        !          8468:     return (0);
        !          8469:   }
        !          8470:     
1.234     brouard  8471:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   8472:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8473:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8474:   }
                   8475:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   8476:     if(nbocc(resultsav,'=') >1){
                   8477:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   8478:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   8479:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   8480:     }else
                   8481:       cutl(strc,strd,resultsav,'=');
1.230     brouard  8482:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  8483:     
1.230     brouard  8484:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   8485:     Tvarsel[k]=atoi(strc);
                   8486:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   8487:     /* cptcovsel++;     */
                   8488:     if (nbocc(stra,'=') >0)
                   8489:       strcpy(resultsav,stra); /* and analyzes it */
                   8490:   }
1.235     brouard  8491:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  8492:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8493:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  8494:       match=0;
1.236     brouard  8495:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  8496:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  8497:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  8498:          match=1;
                   8499:          break;
                   8500:        }
                   8501:       }
                   8502:       if(match == 0){
                   8503:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8504:       }
                   8505:     }
                   8506:   }
1.235     brouard  8507:   /* Checking for missing or useless values in comparison of current model needs */
                   8508:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  8509:     match=0;
1.235     brouard  8510:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8511:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  8512:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  8513:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  8514:          ++match;
                   8515:        }
                   8516:       }
                   8517:     }
                   8518:     if(match == 0){
                   8519:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8520:     }else if(match > 1){
                   8521:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   8522:     }
                   8523:   }
1.235     brouard  8524:       
1.234     brouard  8525:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  8526:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8527:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   8528:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   8529:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   8530:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   8531:   /*    1 0 0 0 */
                   8532:   /*    2 1 0 0 */
                   8533:   /*    3 0 1 0 */ 
                   8534:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   8535:   /*    5 0 0 1 */
                   8536:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   8537:   /*    7 0 1 1 */
                   8538:   /*    8 1 1 1 */
1.237     brouard  8539:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   8540:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   8541:   /* V5*age V5 known which value for nres?  */
                   8542:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  8543:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   8544:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  8545:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  8546:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   8547:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  8548:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   8549:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   8550:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  8551:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   8552:       k4++;;
                   8553:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   8554:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   8555:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  8556:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   8557:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   8558:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  8559:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   8560:       k4q++;;
                   8561:     }
                   8562:   }
1.234     brouard  8563:   
1.235     brouard  8564:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  8565:   return (0);
                   8566: }
1.235     brouard  8567: 
1.230     brouard  8568: int decodemodel( char model[], int lastobs)
                   8569:  /**< This routine decodes the model and returns:
1.224     brouard  8570:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   8571:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   8572:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   8573:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   8574:        * - cptcovage number of covariates with age*products =2
                   8575:        * - cptcovs number of simple covariates
                   8576:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   8577:        *     which is a new column after the 9 (ncovcol) variables. 
                   8578:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   8579:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   8580:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   8581:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   8582:        */
1.136     brouard  8583: {
1.238     brouard  8584:   int i, j, k, ks, v;
1.227     brouard  8585:   int  j1, k1, k2, k3, k4;
1.136     brouard  8586:   char modelsav[80];
1.145     brouard  8587:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  8588:   char *strpt;
1.136     brouard  8589: 
1.145     brouard  8590:   /*removespace(model);*/
1.136     brouard  8591:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  8592:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  8593:     if (strstr(model,"AGE") !=0){
1.192     brouard  8594:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   8595:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  8596:       return 1;
                   8597:     }
1.141     brouard  8598:     if (strstr(model,"v") !=0){
                   8599:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   8600:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   8601:       return 1;
                   8602:     }
1.187     brouard  8603:     strcpy(modelsav,model); 
                   8604:     if ((strpt=strstr(model,"age*age")) !=0){
                   8605:       printf(" strpt=%s, model=%s\n",strpt, model);
                   8606:       if(strpt != model){
1.234     brouard  8607:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8608:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8609:  corresponding column of parameters.\n",model);
1.234     brouard  8610:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8611:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8612:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  8613:        return 1;
1.225     brouard  8614:       }
1.187     brouard  8615:       nagesqr=1;
                   8616:       if (strstr(model,"+age*age") !=0)
1.234     brouard  8617:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  8618:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  8619:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  8620:       else 
1.234     brouard  8621:        substrchaine(modelsav, model, "age*age");
1.187     brouard  8622:     }else
                   8623:       nagesqr=0;
                   8624:     if (strlen(modelsav) >1){
                   8625:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   8626:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  8627:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  8628:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  8629:                     * cst, age and age*age 
                   8630:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   8631:       /* including age products which are counted in cptcovage.
                   8632:        * but the covariates which are products must be treated 
                   8633:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  8634:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   8635:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  8636:       
                   8637:       
1.187     brouard  8638:       /*   Design
                   8639:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   8640:        *  <          ncovcol=8                >
                   8641:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   8642:        *   k=  1    2      3       4     5       6      7        8
                   8643:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   8644:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  8645:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   8646:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  8647:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   8648:        *  Tage[++cptcovage]=k
                   8649:        *       if products, new covar are created after ncovcol with k1
                   8650:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   8651:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   8652:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   8653:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   8654:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   8655:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   8656:        *  <          ncovcol=8                >
                   8657:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   8658:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   8659:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   8660:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8661:        * p Tprod[1]@2={                         6, 5}
                   8662:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   8663:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   8664:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   8665:        *How to reorganize?
                   8666:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   8667:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8668:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   8669:        * Struct []
                   8670:        */
1.225     brouard  8671:       
1.187     brouard  8672:       /* This loop fills the array Tvar from the string 'model'.*/
                   8673:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   8674:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   8675:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   8676:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   8677:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   8678:       /*       k=1 Tvar[1]=2 (from V2) */
                   8679:       /*       k=5 Tvar[5] */
                   8680:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  8681:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  8682:       /*       } */
1.198     brouard  8683:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  8684:       /*
                   8685:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  8686:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   8687:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   8688:       }
1.187     brouard  8689:       cptcovage=0;
                   8690:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  8691:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  8692:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  8693:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   8694:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   8695:        /*scanf("%d",i);*/
                   8696:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   8697:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   8698:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   8699:            /* covar is not filled and then is empty */
                   8700:            cptcovprod--;
                   8701:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   8702:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   8703:            Typevar[k]=1;  /* 1 for age product */
                   8704:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   8705:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   8706:            /*printf("stre=%s ", stre);*/
                   8707:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   8708:            cptcovprod--;
                   8709:            cutl(stre,strb,strc,'V');
                   8710:            Tvar[k]=atoi(stre);
                   8711:            Typevar[k]=1;  /* 1 for age product */
                   8712:            cptcovage++;
                   8713:            Tage[cptcovage]=k;
                   8714:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   8715:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   8716:            cptcovn++;
                   8717:            cptcovprodnoage++;k1++;
                   8718:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   8719:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   8720:                                                because this model-covariate is a construction we invent a new column
                   8721:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   8722:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   8723:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   8724:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   8725:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   8726:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   8727:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   8728:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   8729:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   8730:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   8731:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   8732:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  8733:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  8734:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   8735:            for (i=1; i<=lastobs;i++){
                   8736:              /* Computes the new covariate which is a product of
                   8737:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   8738:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   8739:            }
                   8740:          } /* End age is not in the model */
                   8741:        } /* End if model includes a product */
                   8742:        else { /* no more sum */
                   8743:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   8744:          /*  scanf("%d",i);*/
                   8745:          cutl(strd,strc,strb,'V');
                   8746:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   8747:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   8748:          Tvar[k]=atoi(strd);
                   8749:          Typevar[k]=0;  /* 0 for simple covariates */
                   8750:        }
                   8751:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  8752:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  8753:                                  scanf("%d",i);*/
1.187     brouard  8754:       } /* end of loop + on total covariates */
                   8755:     } /* end if strlen(modelsave == 0) age*age might exist */
                   8756:   } /* end if strlen(model == 0) */
1.136     brouard  8757:   
                   8758:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   8759:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  8760:   
1.136     brouard  8761:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  8762:      printf("cptcovprod=%d ", cptcovprod);
                   8763:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   8764:      scanf("%d ",i);*/
                   8765: 
                   8766: 
1.230     brouard  8767: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   8768:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  8769: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   8770:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   8771:    k =           1    2   3     4       5       6      7      8        9
                   8772:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   8773:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  8774:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   8775:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   8776:          Tmodelind[combination of covar]=k;
1.225     brouard  8777: */  
                   8778: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  8779:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  8780:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  8781:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  8782:   printf("Model=%s\n\
                   8783: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8784: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8785: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8786:   fprintf(ficlog,"Model=%s\n\
                   8787: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8788: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8789: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  8790:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  8791:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   8792:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  8793:       Fixed[k]= 0;
                   8794:       Dummy[k]= 0;
1.225     brouard  8795:       ncoveff++;
1.232     brouard  8796:       ncovf++;
1.234     brouard  8797:       nsd++;
                   8798:       modell[k].maintype= FTYPE;
                   8799:       TvarsD[nsd]=Tvar[k];
                   8800:       TvarsDind[nsd]=k;
                   8801:       TvarF[ncovf]=Tvar[k];
                   8802:       TvarFind[ncovf]=k;
                   8803:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8804:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8805:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   8806:       Fixed[k]= 0;
                   8807:       Dummy[k]= 0;
                   8808:       ncoveff++;
                   8809:       ncovf++;
                   8810:       modell[k].maintype= FTYPE;
                   8811:       TvarF[ncovf]=Tvar[k];
                   8812:       TvarFind[ncovf]=k;
1.230     brouard  8813:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  8814:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  8815:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  8816:       Fixed[k]= 0;
                   8817:       Dummy[k]= 1;
1.230     brouard  8818:       nqfveff++;
1.234     brouard  8819:       modell[k].maintype= FTYPE;
                   8820:       modell[k].subtype= FQ;
                   8821:       nsq++;
                   8822:       TvarsQ[nsq]=Tvar[k];
                   8823:       TvarsQind[nsq]=k;
1.232     brouard  8824:       ncovf++;
1.234     brouard  8825:       TvarF[ncovf]=Tvar[k];
                   8826:       TvarFind[ncovf]=k;
1.231     brouard  8827:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  8828:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  8829:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  8830:       Fixed[k]= 1;
                   8831:       Dummy[k]= 0;
1.225     brouard  8832:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  8833:       modell[k].maintype= VTYPE;
                   8834:       modell[k].subtype= VD;
                   8835:       nsd++;
                   8836:       TvarsD[nsd]=Tvar[k];
                   8837:       TvarsDind[nsd]=k;
                   8838:       ncovv++; /* Only simple time varying variables */
                   8839:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8840:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8841:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   8842:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  8843:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   8844:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  8845:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  8846:       Fixed[k]= 1;
                   8847:       Dummy[k]= 1;
                   8848:       nqtveff++;
                   8849:       modell[k].maintype= VTYPE;
                   8850:       modell[k].subtype= VQ;
                   8851:       ncovv++; /* Only simple time varying variables */
                   8852:       nsq++;
                   8853:       TvarsQ[nsq]=Tvar[k];
                   8854:       TvarsQind[nsq]=k;
                   8855:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8856:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8857:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   8858:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  8859:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   8860:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   8861:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  8862:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  8863:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  8864:       ncova++;
                   8865:       TvarA[ncova]=Tvar[k];
                   8866:       TvarAind[ncova]=k;
1.231     brouard  8867:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  8868:        Fixed[k]= 2;
                   8869:        Dummy[k]= 2;
                   8870:        modell[k].maintype= ATYPE;
                   8871:        modell[k].subtype= APFD;
                   8872:        /* ncoveff++; */
1.227     brouard  8873:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  8874:        Fixed[k]= 2;
                   8875:        Dummy[k]= 3;
                   8876:        modell[k].maintype= ATYPE;
                   8877:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   8878:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  8879:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  8880:        Fixed[k]= 3;
                   8881:        Dummy[k]= 2;
                   8882:        modell[k].maintype= ATYPE;
                   8883:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   8884:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  8885:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  8886:        Fixed[k]= 3;
                   8887:        Dummy[k]= 3;
                   8888:        modell[k].maintype= ATYPE;
                   8889:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   8890:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  8891:       }
                   8892:     }else if (Typevar[k] == 2) {  /* product without age */
                   8893:       k1=Tposprod[k];
                   8894:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  8895:        if(Tvard[k1][2] <=ncovcol){
                   8896:          Fixed[k]= 1;
                   8897:          Dummy[k]= 0;
                   8898:          modell[k].maintype= FTYPE;
                   8899:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   8900:          ncovf++; /* Fixed variables without age */
                   8901:          TvarF[ncovf]=Tvar[k];
                   8902:          TvarFind[ncovf]=k;
                   8903:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8904:          Fixed[k]= 0;  /* or 2 ?*/
                   8905:          Dummy[k]= 1;
                   8906:          modell[k].maintype= FTYPE;
                   8907:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   8908:          ncovf++; /* Varying variables without age */
                   8909:          TvarF[ncovf]=Tvar[k];
                   8910:          TvarFind[ncovf]=k;
                   8911:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8912:          Fixed[k]= 1;
                   8913:          Dummy[k]= 0;
                   8914:          modell[k].maintype= VTYPE;
                   8915:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   8916:          ncovv++; /* Varying variables without age */
                   8917:          TvarV[ncovv]=Tvar[k];
                   8918:          TvarVind[ncovv]=k;
                   8919:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8920:          Fixed[k]= 1;
                   8921:          Dummy[k]= 1;
                   8922:          modell[k].maintype= VTYPE;
                   8923:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   8924:          ncovv++; /* Varying variables without age */
                   8925:          TvarV[ncovv]=Tvar[k];
                   8926:          TvarVind[ncovv]=k;
                   8927:        }
1.227     brouard  8928:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  8929:        if(Tvard[k1][2] <=ncovcol){
                   8930:          Fixed[k]= 0;  /* or 2 ?*/
                   8931:          Dummy[k]= 1;
                   8932:          modell[k].maintype= FTYPE;
                   8933:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   8934:          ncovf++; /* Fixed variables without age */
                   8935:          TvarF[ncovf]=Tvar[k];
                   8936:          TvarFind[ncovf]=k;
                   8937:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8938:          Fixed[k]= 1;
                   8939:          Dummy[k]= 1;
                   8940:          modell[k].maintype= VTYPE;
                   8941:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   8942:          ncovv++; /* Varying variables without age */
                   8943:          TvarV[ncovv]=Tvar[k];
                   8944:          TvarVind[ncovv]=k;
                   8945:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8946:          Fixed[k]= 1;
                   8947:          Dummy[k]= 1;
                   8948:          modell[k].maintype= VTYPE;
                   8949:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   8950:          ncovv++; /* Varying variables without age */
                   8951:          TvarV[ncovv]=Tvar[k];
                   8952:          TvarVind[ncovv]=k;
                   8953:          ncovv++; /* Varying variables without age */
                   8954:          TvarV[ncovv]=Tvar[k];
                   8955:          TvarVind[ncovv]=k;
                   8956:        }
1.227     brouard  8957:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  8958:        if(Tvard[k1][2] <=ncovcol){
                   8959:          Fixed[k]= 1;
                   8960:          Dummy[k]= 1;
                   8961:          modell[k].maintype= VTYPE;
                   8962:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   8963:          ncovv++; /* Varying variables without age */
                   8964:          TvarV[ncovv]=Tvar[k];
                   8965:          TvarVind[ncovv]=k;
                   8966:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8967:          Fixed[k]= 1;
                   8968:          Dummy[k]= 1;
                   8969:          modell[k].maintype= VTYPE;
                   8970:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   8971:          ncovv++; /* Varying variables without age */
                   8972:          TvarV[ncovv]=Tvar[k];
                   8973:          TvarVind[ncovv]=k;
                   8974:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8975:          Fixed[k]= 1;
                   8976:          Dummy[k]= 0;
                   8977:          modell[k].maintype= VTYPE;
                   8978:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   8979:          ncovv++; /* Varying variables without age */
                   8980:          TvarV[ncovv]=Tvar[k];
                   8981:          TvarVind[ncovv]=k;
                   8982:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8983:          Fixed[k]= 1;
                   8984:          Dummy[k]= 1;
                   8985:          modell[k].maintype= VTYPE;
                   8986:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   8987:          ncovv++; /* Varying variables without age */
                   8988:          TvarV[ncovv]=Tvar[k];
                   8989:          TvarVind[ncovv]=k;
                   8990:        }
1.227     brouard  8991:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  8992:        if(Tvard[k1][2] <=ncovcol){
                   8993:          Fixed[k]= 1;
                   8994:          Dummy[k]= 1;
                   8995:          modell[k].maintype= VTYPE;
                   8996:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   8997:          ncovv++; /* Varying variables without age */
                   8998:          TvarV[ncovv]=Tvar[k];
                   8999:          TvarVind[ncovv]=k;
                   9000:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9001:          Fixed[k]= 1;
                   9002:          Dummy[k]= 1;
                   9003:          modell[k].maintype= VTYPE;
                   9004:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9005:          ncovv++; /* Varying variables without age */
                   9006:          TvarV[ncovv]=Tvar[k];
                   9007:          TvarVind[ncovv]=k;
                   9008:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9009:          Fixed[k]= 1;
                   9010:          Dummy[k]= 1;
                   9011:          modell[k].maintype= VTYPE;
                   9012:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9013:          ncovv++; /* Varying variables without age */
                   9014:          TvarV[ncovv]=Tvar[k];
                   9015:          TvarVind[ncovv]=k;
                   9016:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9017:          Fixed[k]= 1;
                   9018:          Dummy[k]= 1;
                   9019:          modell[k].maintype= VTYPE;
                   9020:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9021:          ncovv++; /* Varying variables without age */
                   9022:          TvarV[ncovv]=Tvar[k];
                   9023:          TvarVind[ncovv]=k;
                   9024:        }
1.227     brouard  9025:       }else{
1.240     brouard  9026:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9027:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9028:       } /*end k1*/
1.225     brouard  9029:     }else{
1.226     brouard  9030:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9031:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9032:     }
1.227     brouard  9033:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9034:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9035:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9036:   }
                   9037:   /* Searching for doublons in the model */
                   9038:   for(k1=1; k1<= cptcovt;k1++){
                   9039:     for(k2=1; k2 <k1;k2++){
                   9040:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  9041:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9042:          if(Tvar[k1]==Tvar[k2]){
                   9043:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9044:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9045:            return(1);
                   9046:          }
                   9047:        }else if (Typevar[k1] ==2){
                   9048:          k3=Tposprod[k1];
                   9049:          k4=Tposprod[k2];
                   9050:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   9051:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9052:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9053:            return(1);
                   9054:          }
                   9055:        }
1.227     brouard  9056:       }
                   9057:     }
1.225     brouard  9058:   }
                   9059:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   9060:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  9061:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   9062:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  9063:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  9064:   /*endread:*/
1.225     brouard  9065:   printf("Exiting decodemodel: ");
                   9066:   return (1);
1.136     brouard  9067: }
                   9068: 
1.169     brouard  9069: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  9070: {/* Check ages at death */
1.136     brouard  9071:   int i, m;
1.218     brouard  9072:   int firstone=0;
                   9073:   
1.136     brouard  9074:   for (i=1; i<=imx; i++) {
                   9075:     for(m=2; (m<= maxwav); m++) {
                   9076:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   9077:        anint[m][i]=9999;
1.216     brouard  9078:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   9079:          s[m][i]=-1;
1.136     brouard  9080:       }
                   9081:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.169     brouard  9082:        *nberr = *nberr + 1;
1.218     brouard  9083:        if(firstone == 0){
                   9084:          firstone=1;
                   9085:        printf("Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\nOther similar cases in log file\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
                   9086:        }
                   9087:        fprintf(ficlog,"Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
1.136     brouard  9088:        s[m][i]=-1;
                   9089:       }
                   9090:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  9091:        (*nberr)++;
1.136     brouard  9092:        printf("Error! Month of death of individual %ld on line %d was unknown %2d, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,(int)moisdc[i]); 
                   9093:        fprintf(ficlog,"Error! Month of death of individual %ld on line %d was unknown %f, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,moisdc[i]); 
                   9094:        s[m][i]=-1; /* We prefer to skip it (and to skip it in version 0.8a1 too */
                   9095:       }
                   9096:     }
                   9097:   }
                   9098: 
                   9099:   for (i=1; i<=imx; i++)  {
                   9100:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   9101:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  9102:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  9103:        if (s[m][i] >= nlstate+1) {
1.169     brouard  9104:          if(agedc[i]>0){
                   9105:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  9106:              agev[m][i]=agedc[i];
1.214     brouard  9107:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  9108:            }else {
1.136     brouard  9109:              if ((int)andc[i]!=9999){
                   9110:                nbwarn++;
                   9111:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   9112:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   9113:                agev[m][i]=-1;
                   9114:              }
                   9115:            }
1.169     brouard  9116:          } /* agedc > 0 */
1.214     brouard  9117:        } /* end if */
1.136     brouard  9118:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   9119:                                 years but with the precision of a month */
                   9120:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   9121:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   9122:            agev[m][i]=1;
                   9123:          else if(agev[m][i] < *agemin){ 
                   9124:            *agemin=agev[m][i];
                   9125:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   9126:          }
                   9127:          else if(agev[m][i] >*agemax){
                   9128:            *agemax=agev[m][i];
1.156     brouard  9129:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  9130:          }
                   9131:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   9132:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  9133:        } /* en if 9*/
1.136     brouard  9134:        else { /* =9 */
1.214     brouard  9135:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  9136:          agev[m][i]=1;
                   9137:          s[m][i]=-1;
                   9138:        }
                   9139:       }
1.214     brouard  9140:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  9141:        agev[m][i]=1;
1.214     brouard  9142:       else{
                   9143:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9144:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9145:        agev[m][i]=0;
                   9146:       }
                   9147:     } /* End for lastpass */
                   9148:   }
1.136     brouard  9149:     
                   9150:   for (i=1; i<=imx; i++)  {
                   9151:     for(m=firstpass; (m<=lastpass); m++){
                   9152:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  9153:        (*nberr)++;
1.136     brouard  9154:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9155:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9156:        return 1;
                   9157:       }
                   9158:     }
                   9159:   }
                   9160: 
                   9161:   /*for (i=1; i<=imx; i++){
                   9162:   for (m=firstpass; (m<lastpass); m++){
                   9163:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   9164: }
                   9165: 
                   9166: }*/
                   9167: 
                   9168: 
1.139     brouard  9169:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   9170:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  9171: 
                   9172:   return (0);
1.164     brouard  9173:  /* endread:*/
1.136     brouard  9174:     printf("Exiting calandcheckages: ");
                   9175:     return (1);
                   9176: }
                   9177: 
1.172     brouard  9178: #if defined(_MSC_VER)
                   9179: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9180: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9181: //#include "stdafx.h"
                   9182: //#include <stdio.h>
                   9183: //#include <tchar.h>
                   9184: //#include <windows.h>
                   9185: //#include <iostream>
                   9186: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   9187: 
                   9188: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9189: 
                   9190: BOOL IsWow64()
                   9191: {
                   9192:        BOOL bIsWow64 = FALSE;
                   9193: 
                   9194:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   9195:        //  (HANDLE, PBOOL);
                   9196: 
                   9197:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9198: 
                   9199:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   9200:        const char funcName[] = "IsWow64Process";
                   9201:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   9202:                GetProcAddress(module, funcName);
                   9203: 
                   9204:        if (NULL != fnIsWow64Process)
                   9205:        {
                   9206:                if (!fnIsWow64Process(GetCurrentProcess(),
                   9207:                        &bIsWow64))
                   9208:                        //throw std::exception("Unknown error");
                   9209:                        printf("Unknown error\n");
                   9210:        }
                   9211:        return bIsWow64 != FALSE;
                   9212: }
                   9213: #endif
1.177     brouard  9214: 
1.191     brouard  9215: void syscompilerinfo(int logged)
1.167     brouard  9216:  {
                   9217:    /* #include "syscompilerinfo.h"*/
1.185     brouard  9218:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   9219:    /* /GS /W3 /Gy
                   9220:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   9221:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   9222:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  9223:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   9224:    */ 
                   9225:    /* 64 bits */
1.185     brouard  9226:    /*
                   9227:      /GS /W3 /Gy
                   9228:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   9229:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   9230:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   9231:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   9232:    /* Optimization are useless and O3 is slower than O2 */
                   9233:    /*
                   9234:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   9235:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   9236:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   9237:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   9238:    */
1.186     brouard  9239:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  9240:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   9241:       /PDB:"visual studio
                   9242:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   9243:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   9244:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   9245:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   9246:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   9247:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   9248:       uiAccess='false'"
                   9249:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   9250:       /NOLOGO /TLBID:1
                   9251:    */
1.177     brouard  9252: #if defined __INTEL_COMPILER
1.178     brouard  9253: #if defined(__GNUC__)
                   9254:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   9255: #endif
1.177     brouard  9256: #elif defined(__GNUC__) 
1.179     brouard  9257: #ifndef  __APPLE__
1.174     brouard  9258: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  9259: #endif
1.177     brouard  9260:    struct utsname sysInfo;
1.178     brouard  9261:    int cross = CROSS;
                   9262:    if (cross){
                   9263:           printf("Cross-");
1.191     brouard  9264:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  9265:    }
1.174     brouard  9266: #endif
                   9267: 
1.171     brouard  9268: #include <stdint.h>
1.178     brouard  9269: 
1.191     brouard  9270:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  9271: #if defined(__clang__)
1.191     brouard  9272:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  9273: #endif
                   9274: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  9275:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  9276: #endif
                   9277: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  9278:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  9279: #endif
                   9280: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  9281:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  9282: #endif
                   9283: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  9284:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  9285: #endif
                   9286: #if defined(_MSC_VER)
1.191     brouard  9287:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  9288: #endif
                   9289: #if defined(__PGI)
1.191     brouard  9290:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  9291: #endif
                   9292: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  9293:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  9294: #endif
1.191     brouard  9295:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  9296:    
1.167     brouard  9297: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   9298: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   9299:     // Windows (x64 and x86)
1.191     brouard  9300:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  9301: #elif __unix__ // all unices, not all compilers
                   9302:     // Unix
1.191     brouard  9303:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  9304: #elif __linux__
                   9305:     // linux
1.191     brouard  9306:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  9307: #elif __APPLE__
1.174     brouard  9308:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  9309:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  9310: #endif
                   9311: 
                   9312: /*  __MINGW32__          */
                   9313: /*  __CYGWIN__  */
                   9314: /* __MINGW64__  */
                   9315: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   9316: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   9317: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   9318: /* _WIN64  // Defined for applications for Win64. */
                   9319: /* _M_X64 // Defined for compilations that target x64 processors. */
                   9320: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  9321: 
1.167     brouard  9322: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  9323:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  9324: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  9325:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  9326: #else
1.191     brouard  9327:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  9328: #endif
                   9329: 
1.169     brouard  9330: #if defined(__GNUC__)
                   9331: # if defined(__GNUC_PATCHLEVEL__)
                   9332: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9333:                             + __GNUC_MINOR__ * 100 \
                   9334:                             + __GNUC_PATCHLEVEL__)
                   9335: # else
                   9336: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9337:                             + __GNUC_MINOR__ * 100)
                   9338: # endif
1.174     brouard  9339:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  9340:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  9341: 
                   9342:    if (uname(&sysInfo) != -1) {
                   9343:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  9344:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  9345:    }
                   9346:    else
                   9347:       perror("uname() error");
1.179     brouard  9348:    //#ifndef __INTEL_COMPILER 
                   9349: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  9350:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  9351:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  9352: #endif
1.169     brouard  9353: #endif
1.172     brouard  9354: 
                   9355:    //   void main()
                   9356:    //   {
1.169     brouard  9357: #if defined(_MSC_VER)
1.174     brouard  9358:    if (IsWow64()){
1.191     brouard  9359:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   9360:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  9361:    }
                   9362:    else{
1.191     brouard  9363:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   9364:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  9365:    }
1.172     brouard  9366:    //     printf("\nPress Enter to continue...");
                   9367:    //     getchar();
                   9368:    //   }
                   9369: 
1.169     brouard  9370: #endif
                   9371:    
1.167     brouard  9372: 
1.219     brouard  9373: }
1.136     brouard  9374: 
1.219     brouard  9375: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  9376:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  9377:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  9378:   /* double ftolpl = 1.e-10; */
1.180     brouard  9379:   double age, agebase, agelim;
1.203     brouard  9380:   double tot;
1.180     brouard  9381: 
1.202     brouard  9382:   strcpy(filerespl,"PL_");
                   9383:   strcat(filerespl,fileresu);
                   9384:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   9385:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9386:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9387:   }
1.227     brouard  9388:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   9389:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  9390:   pstamp(ficrespl);
1.203     brouard  9391:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  9392:   fprintf(ficrespl,"#Age ");
                   9393:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   9394:   fprintf(ficrespl,"\n");
1.180     brouard  9395:   
1.219     brouard  9396:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  9397: 
1.219     brouard  9398:   agebase=ageminpar;
                   9399:   agelim=agemaxpar;
1.180     brouard  9400: 
1.227     brouard  9401:   /* i1=pow(2,ncoveff); */
1.234     brouard  9402:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  9403:   if (cptcovn < 1){i1=1;}
1.180     brouard  9404: 
1.238     brouard  9405:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   9406:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253   ! brouard  9407:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9408:        continue;
1.235     brouard  9409: 
1.238     brouard  9410:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9411:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   9412:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   9413:       /* k=k+1; */
                   9414:       /* to clean */
                   9415:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9416:       fprintf(ficrespl,"#******");
                   9417:       printf("#******");
                   9418:       fprintf(ficlog,"#******");
                   9419:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9420:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   9421:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9422:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9423:       }
                   9424:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9425:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9426:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9427:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9428:       }
                   9429:       fprintf(ficrespl,"******\n");
                   9430:       printf("******\n");
                   9431:       fprintf(ficlog,"******\n");
                   9432:       if(invalidvarcomb[k]){
                   9433:        printf("\nCombination (%d) ignored because no case \n",k); 
                   9434:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   9435:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   9436:        continue;
                   9437:       }
1.219     brouard  9438: 
1.238     brouard  9439:       fprintf(ficrespl,"#Age ");
                   9440:       for(j=1;j<=cptcoveff;j++) {
                   9441:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9442:       }
                   9443:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   9444:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  9445:     
1.238     brouard  9446:       for (age=agebase; age<=agelim; age++){
                   9447:        /* for (age=agebase; age<=agebase; age++){ */
                   9448:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   9449:        fprintf(ficrespl,"%.0f ",age );
                   9450:        for(j=1;j<=cptcoveff;j++)
                   9451:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9452:        tot=0.;
                   9453:        for(i=1; i<=nlstate;i++){
                   9454:          tot +=  prlim[i][i];
                   9455:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   9456:        }
                   9457:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   9458:       } /* Age */
                   9459:       /* was end of cptcod */
                   9460:     } /* cptcov */
                   9461:   } /* nres */
1.219     brouard  9462:   return 0;
1.180     brouard  9463: }
                   9464: 
1.218     brouard  9465: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   9466:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   9467:        
                   9468:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   9469:    * at any age between ageminpar and agemaxpar
                   9470:         */
1.235     brouard  9471:   int i, j, k, i1, nres=0 ;
1.217     brouard  9472:   /* double ftolpl = 1.e-10; */
                   9473:   double age, agebase, agelim;
                   9474:   double tot;
1.218     brouard  9475:   /* double ***mobaverage; */
                   9476:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  9477: 
                   9478:   strcpy(fileresplb,"PLB_");
                   9479:   strcat(fileresplb,fileresu);
                   9480:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   9481:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9482:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9483:   }
                   9484:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9485:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9486:   pstamp(ficresplb);
                   9487:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   9488:   fprintf(ficresplb,"#Age ");
                   9489:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   9490:   fprintf(ficresplb,"\n");
                   9491:   
1.218     brouard  9492:   
                   9493:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   9494:   
                   9495:   agebase=ageminpar;
                   9496:   agelim=agemaxpar;
                   9497:   
                   9498:   
1.227     brouard  9499:   i1=pow(2,cptcoveff);
1.218     brouard  9500:   if (cptcovn < 1){i1=1;}
1.227     brouard  9501:   
1.238     brouard  9502:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9503:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253   ! brouard  9504:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9505:        continue;
                   9506:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9507:       fprintf(ficresplb,"#******");
                   9508:       printf("#******");
                   9509:       fprintf(ficlog,"#******");
                   9510:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9511:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9512:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9513:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9514:       }
                   9515:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9516:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9517:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9518:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9519:       }
                   9520:       fprintf(ficresplb,"******\n");
                   9521:       printf("******\n");
                   9522:       fprintf(ficlog,"******\n");
                   9523:       if(invalidvarcomb[k]){
                   9524:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   9525:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   9526:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   9527:        continue;
                   9528:       }
1.218     brouard  9529:     
1.238     brouard  9530:       fprintf(ficresplb,"#Age ");
                   9531:       for(j=1;j<=cptcoveff;j++) {
                   9532:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9533:       }
                   9534:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   9535:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  9536:     
                   9537:     
1.238     brouard  9538:       for (age=agebase; age<=agelim; age++){
                   9539:        /* for (age=agebase; age<=agebase; age++){ */
                   9540:        if(mobilavproj > 0){
                   9541:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   9542:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9543:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  9544:        }else if (mobilavproj == 0){
                   9545:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9546:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9547:          exit(1);
                   9548:        }else{
                   9549:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9550:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.238     brouard  9551:        }
                   9552:        fprintf(ficresplb,"%.0f ",age );
                   9553:        for(j=1;j<=cptcoveff;j++)
                   9554:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9555:        tot=0.;
                   9556:        for(i=1; i<=nlstate;i++){
                   9557:          tot +=  bprlim[i][i];
                   9558:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   9559:        }
                   9560:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   9561:       } /* Age */
                   9562:       /* was end of cptcod */
                   9563:     } /* end of any combination */
                   9564:   } /* end of nres */  
1.218     brouard  9565:   /* hBijx(p, bage, fage); */
                   9566:   /* fclose(ficrespijb); */
                   9567:   
                   9568:   return 0;
1.217     brouard  9569: }
1.218     brouard  9570:  
1.180     brouard  9571: int hPijx(double *p, int bage, int fage){
                   9572:     /*------------- h Pij x at various ages ------------*/
                   9573: 
                   9574:   int stepsize;
                   9575:   int agelim;
                   9576:   int hstepm;
                   9577:   int nhstepm;
1.235     brouard  9578:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  9579: 
                   9580:   double agedeb;
                   9581:   double ***p3mat;
                   9582: 
1.201     brouard  9583:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  9584:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   9585:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9586:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9587:     }
                   9588:     printf("Computing pij: result on file '%s' \n", filerespij);
                   9589:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   9590:   
                   9591:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9592:     /*if (stepm<=24) stepsize=2;*/
                   9593: 
                   9594:     agelim=AGESUP;
                   9595:     hstepm=stepsize*YEARM; /* Every year of age */
                   9596:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  9597:                
1.180     brouard  9598:     /* hstepm=1;   aff par mois*/
                   9599:     pstamp(ficrespij);
                   9600:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  9601:     i1= pow(2,cptcoveff);
1.218     brouard  9602:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9603:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9604:                /*      k=k+1;  */
1.235     brouard  9605:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9606:     for(k=1; k<=i1;k++){
1.253   ! brouard  9607:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  9608:        continue;
1.183     brouard  9609:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  9610:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  9611:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  9612:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9613:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9614:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9615:       }
1.183     brouard  9616:       fprintf(ficrespij,"******\n");
                   9617:       
                   9618:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   9619:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   9620:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   9621:        
                   9622:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  9623:        
1.183     brouard  9624:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9625:        oldm=oldms;savm=savms;
1.235     brouard  9626:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  9627:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   9628:        for(i=1; i<=nlstate;i++)
                   9629:          for(j=1; j<=nlstate+ndeath;j++)
                   9630:            fprintf(ficrespij," %1d-%1d",i,j);
                   9631:        fprintf(ficrespij,"\n");
                   9632:        for (h=0; h<=nhstepm; h++){
                   9633:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9634:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  9635:          for(i=1; i<=nlstate;i++)
                   9636:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  9637:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  9638:          fprintf(ficrespij,"\n");
                   9639:        }
1.183     brouard  9640:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9641:        fprintf(ficrespij,"\n");
                   9642:       }
1.180     brouard  9643:       /*}*/
                   9644:     }
1.218     brouard  9645:     return 0;
1.180     brouard  9646: }
1.218     brouard  9647:  
                   9648:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  9649:     /*------------- h Bij x at various ages ------------*/
                   9650: 
                   9651:   int stepsize;
1.218     brouard  9652:   /* int agelim; */
                   9653:        int ageminl;
1.217     brouard  9654:   int hstepm;
                   9655:   int nhstepm;
1.238     brouard  9656:   int h, i, i1, j, k, nres;
1.218     brouard  9657:        
1.217     brouard  9658:   double agedeb;
                   9659:   double ***p3mat;
1.218     brouard  9660:        
                   9661:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   9662:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   9663:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9664:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9665:   }
                   9666:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   9667:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   9668:   
                   9669:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9670:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  9671:   
1.218     brouard  9672:   /* agelim=AGESUP; */
                   9673:   ageminl=30;
                   9674:   hstepm=stepsize*YEARM; /* Every year of age */
                   9675:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   9676:   
                   9677:   /* hstepm=1;   aff par mois*/
                   9678:   pstamp(ficrespijb);
                   9679:   fprintf(ficrespijb,"#****** h Pij x Back Probability to be in state i at age x-h being in j at x ");
1.227     brouard  9680:   i1= pow(2,cptcoveff);
1.218     brouard  9681:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9682:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9683:   /*   k=k+1;  */
1.238     brouard  9684:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9685:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253   ! brouard  9686:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9687:        continue;
                   9688:       fprintf(ficrespijb,"\n#****** ");
                   9689:       for(j=1;j<=cptcoveff;j++)
                   9690:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9691:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9692:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9693:       }
                   9694:       fprintf(ficrespijb,"******\n");
                   9695:       if(invalidvarcomb[k]){
                   9696:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   9697:        continue;
                   9698:       }
                   9699:       
                   9700:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   9701:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   9702:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   9703:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   9704:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   9705:        
                   9706:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   9707:        
                   9708:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9709:        /* oldm=oldms;savm=savms; */
                   9710:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9711:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k);
                   9712:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
                   9713:        fprintf(ficrespijb,"# Cov Agex agex-h hpijx with i,j=");
1.217     brouard  9714:        for(i=1; i<=nlstate;i++)
                   9715:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  9716:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  9717:        fprintf(ficrespijb,"\n");
1.238     brouard  9718:        for (h=0; h<=nhstepm; h++){
                   9719:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9720:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   9721:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   9722:          for(i=1; i<=nlstate;i++)
                   9723:            for(j=1; j<=nlstate+ndeath;j++)
                   9724:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   9725:          fprintf(ficrespijb,"\n");
                   9726:        }
                   9727:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9728:        fprintf(ficrespijb,"\n");
                   9729:       } /* end age deb */
                   9730:     } /* end combination */
                   9731:   } /* end nres */
1.218     brouard  9732:   return 0;
                   9733:  } /*  hBijx */
1.217     brouard  9734: 
1.180     brouard  9735: 
1.136     brouard  9736: /***********************************************/
                   9737: /**************** Main Program *****************/
                   9738: /***********************************************/
                   9739: 
                   9740: int main(int argc, char *argv[])
                   9741: {
                   9742: #ifdef GSL
                   9743:   const gsl_multimin_fminimizer_type *T;
                   9744:   size_t iteri = 0, it;
                   9745:   int rval = GSL_CONTINUE;
                   9746:   int status = GSL_SUCCESS;
                   9747:   double ssval;
                   9748: #endif
                   9749:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  9750:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  9751:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  9752:   int jj, ll, li, lj, lk;
1.136     brouard  9753:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  9754:   int num_filled;
1.136     brouard  9755:   int itimes;
                   9756:   int NDIM=2;
                   9757:   int vpopbased=0;
1.235     brouard  9758:   int nres=0;
1.136     brouard  9759: 
1.164     brouard  9760:   char ca[32], cb[32];
1.136     brouard  9761:   /*  FILE *fichtm; *//* Html File */
                   9762:   /* FILE *ficgp;*/ /*Gnuplot File */
                   9763:   struct stat info;
1.191     brouard  9764:   double agedeb=0.;
1.194     brouard  9765: 
                   9766:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  9767:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  9768: 
1.165     brouard  9769:   double fret;
1.191     brouard  9770:   double dum=0.; /* Dummy variable */
1.136     brouard  9771:   double ***p3mat;
1.218     brouard  9772:   /* double ***mobaverage; */
1.164     brouard  9773: 
                   9774:   char line[MAXLINE];
1.197     brouard  9775:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   9776: 
1.234     brouard  9777:   char  modeltemp[MAXLINE];
1.230     brouard  9778:   char resultline[MAXLINE];
                   9779:   
1.136     brouard  9780:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  9781:   char *tok, *val; /* pathtot */
1.136     brouard  9782:   int firstobs=1, lastobs=10;
1.195     brouard  9783:   int c,  h , cpt, c2;
1.191     brouard  9784:   int jl=0;
                   9785:   int i1, j1, jk, stepsize=0;
1.194     brouard  9786:   int count=0;
                   9787: 
1.164     brouard  9788:   int *tab; 
1.136     brouard  9789:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  9790:   int backcast=0;
1.136     brouard  9791:   int mobilav=0,popforecast=0;
1.191     brouard  9792:   int hstepm=0, nhstepm=0;
1.136     brouard  9793:   int agemortsup;
                   9794:   float  sumlpop=0.;
                   9795:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   9796:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   9797: 
1.191     brouard  9798:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  9799:   double ftolpl=FTOL;
                   9800:   double **prlim;
1.217     brouard  9801:   double **bprlim;
1.136     brouard  9802:   double ***param; /* Matrix of parameters */
1.251     brouard  9803:   double ***paramstart; /* Matrix of starting parameter values */
                   9804:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  9805:   double **matcov; /* Matrix of covariance */
1.203     brouard  9806:   double **hess; /* Hessian matrix */
1.136     brouard  9807:   double ***delti3; /* Scale */
                   9808:   double *delti; /* Scale */
                   9809:   double ***eij, ***vareij;
                   9810:   double **varpl; /* Variances of prevalence limits by age */
                   9811:   double *epj, vepp;
1.164     brouard  9812: 
1.136     brouard  9813:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  9814:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   9815: 
1.136     brouard  9816:   double **ximort;
1.145     brouard  9817:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  9818:   int *dcwave;
                   9819: 
1.164     brouard  9820:   char z[1]="c";
1.136     brouard  9821: 
                   9822:   /*char  *strt;*/
                   9823:   char strtend[80];
1.126     brouard  9824: 
1.164     brouard  9825: 
1.126     brouard  9826: /*   setlocale (LC_ALL, ""); */
                   9827: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   9828: /*   textdomain (PACKAGE); */
                   9829: /*   setlocale (LC_CTYPE, ""); */
                   9830: /*   setlocale (LC_MESSAGES, ""); */
                   9831: 
                   9832:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  9833:   rstart_time = time(NULL);  
                   9834:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   9835:   start_time = *localtime(&rstart_time);
1.126     brouard  9836:   curr_time=start_time;
1.157     brouard  9837:   /*tml = *localtime(&start_time.tm_sec);*/
                   9838:   /* strcpy(strstart,asctime(&tml)); */
                   9839:   strcpy(strstart,asctime(&start_time));
1.126     brouard  9840: 
                   9841: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  9842: /*  tp.tm_sec = tp.tm_sec +86400; */
                   9843: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  9844: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   9845: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   9846: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  9847: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  9848: /*   strt=asctime(&tmg); */
                   9849: /*   printf("Time(after) =%s",strstart);  */
                   9850: /*  (void) time (&time_value);
                   9851: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   9852: *  tm = *localtime(&time_value);
                   9853: *  strstart=asctime(&tm);
                   9854: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   9855: */
                   9856: 
                   9857:   nberr=0; /* Number of errors and warnings */
                   9858:   nbwarn=0;
1.184     brouard  9859: #ifdef WIN32
                   9860:   _getcwd(pathcd, size);
                   9861: #else
1.126     brouard  9862:   getcwd(pathcd, size);
1.184     brouard  9863: #endif
1.191     brouard  9864:   syscompilerinfo(0);
1.196     brouard  9865:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  9866:   if(argc <=1){
                   9867:     printf("\nEnter the parameter file name: ");
1.205     brouard  9868:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   9869:       printf("ERROR Empty parameter file name\n");
                   9870:       goto end;
                   9871:     }
1.126     brouard  9872:     i=strlen(pathr);
                   9873:     if(pathr[i-1]=='\n')
                   9874:       pathr[i-1]='\0';
1.156     brouard  9875:     i=strlen(pathr);
1.205     brouard  9876:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  9877:       pathr[i-1]='\0';
1.205     brouard  9878:     }
                   9879:     i=strlen(pathr);
                   9880:     if( i==0 ){
                   9881:       printf("ERROR Empty parameter file name\n");
                   9882:       goto end;
                   9883:     }
                   9884:     for (tok = pathr; tok != NULL; ){
1.126     brouard  9885:       printf("Pathr |%s|\n",pathr);
                   9886:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   9887:       printf("val= |%s| pathr=%s\n",val,pathr);
                   9888:       strcpy (pathtot, val);
                   9889:       if(pathr[0] == '\0') break; /* Dirty */
                   9890:     }
                   9891:   }
                   9892:   else{
                   9893:     strcpy(pathtot,argv[1]);
                   9894:   }
                   9895:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   9896:   /*cygwin_split_path(pathtot,path,optionfile);
                   9897:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   9898:   /* cutv(path,optionfile,pathtot,'\\');*/
                   9899: 
                   9900:   /* Split argv[0], imach program to get pathimach */
                   9901:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   9902:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9903:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9904:  /*   strcpy(pathimach,argv[0]); */
                   9905:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   9906:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   9907:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  9908: #ifdef WIN32
                   9909:   _chdir(path); /* Can be a relative path */
                   9910:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   9911: #else
1.126     brouard  9912:   chdir(path); /* Can be a relative path */
1.184     brouard  9913:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   9914: #endif
                   9915:   printf("Current directory %s!\n",pathcd);
1.126     brouard  9916:   strcpy(command,"mkdir ");
                   9917:   strcat(command,optionfilefiname);
                   9918:   if((outcmd=system(command)) != 0){
1.169     brouard  9919:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  9920:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   9921:     /* fclose(ficlog); */
                   9922: /*     exit(1); */
                   9923:   }
                   9924: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   9925: /*     perror("mkdir"); */
                   9926: /*   } */
                   9927: 
                   9928:   /*-------- arguments in the command line --------*/
                   9929: 
1.186     brouard  9930:   /* Main Log file */
1.126     brouard  9931:   strcat(filelog, optionfilefiname);
                   9932:   strcat(filelog,".log");    /* */
                   9933:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   9934:     printf("Problem with logfile %s\n",filelog);
                   9935:     goto end;
                   9936:   }
                   9937:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  9938:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  9939:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   9940:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   9941:  path=%s \n\
                   9942:  optionfile=%s\n\
                   9943:  optionfilext=%s\n\
1.156     brouard  9944:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  9945: 
1.197     brouard  9946:   syscompilerinfo(1);
1.167     brouard  9947: 
1.126     brouard  9948:   printf("Local time (at start):%s",strstart);
                   9949:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   9950:   fflush(ficlog);
                   9951: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  9952: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  9953: 
                   9954:   /* */
                   9955:   strcpy(fileres,"r");
                   9956:   strcat(fileres, optionfilefiname);
1.201     brouard  9957:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  9958:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  9959:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  9960: 
1.186     brouard  9961:   /* Main ---------arguments file --------*/
1.126     brouard  9962: 
                   9963:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  9964:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   9965:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  9966:     fflush(ficlog);
1.149     brouard  9967:     /* goto end; */
                   9968:     exit(70); 
1.126     brouard  9969:   }
                   9970: 
                   9971: 
                   9972: 
                   9973:   strcpy(filereso,"o");
1.201     brouard  9974:   strcat(filereso,fileresu);
1.126     brouard  9975:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   9976:     printf("Problem with Output resultfile: %s\n", filereso);
                   9977:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   9978:     fflush(ficlog);
                   9979:     goto end;
                   9980:   }
                   9981: 
                   9982:   /* Reads comments: lines beginning with '#' */
                   9983:   numlinepar=0;
1.197     brouard  9984: 
                   9985:     /* First parameter line */
                   9986:   while(fgets(line, MAXLINE, ficpar)) {
                   9987:     /* If line starts with a # it is a comment */
                   9988:     if (line[0] == '#') {
                   9989:       numlinepar++;
                   9990:       fputs(line,stdout);
                   9991:       fputs(line,ficparo);
                   9992:       fputs(line,ficlog);
                   9993:       continue;
                   9994:     }else
                   9995:       break;
                   9996:   }
                   9997:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   9998:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   9999:     if (num_filled != 5) {
                   10000:       printf("Should be 5 parameters\n");
                   10001:     }
1.126     brouard  10002:     numlinepar++;
1.197     brouard  10003:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   10004:   }
                   10005:   /* Second parameter line */
                   10006:   while(fgets(line, MAXLINE, ficpar)) {
                   10007:     /* If line starts with a # it is a comment */
                   10008:     if (line[0] == '#') {
                   10009:       numlinepar++;
                   10010:       fputs(line,stdout);
                   10011:       fputs(line,ficparo);
                   10012:       fputs(line,ficlog);
                   10013:       continue;
                   10014:     }else
                   10015:       break;
                   10016:   }
1.223     brouard  10017:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   10018:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   10019:     if (num_filled != 11) {
                   10020:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  10021:       printf("but line=%s\n",line);
1.197     brouard  10022:     }
1.223     brouard  10023:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  10024:   }
1.203     brouard  10025:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  10026:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  10027:   /* Third parameter line */
                   10028:   while(fgets(line, MAXLINE, ficpar)) {
                   10029:     /* If line starts with a # it is a comment */
                   10030:     if (line[0] == '#') {
                   10031:       numlinepar++;
                   10032:       fputs(line,stdout);
                   10033:       fputs(line,ficparo);
                   10034:       fputs(line,ficlog);
                   10035:       continue;
                   10036:     }else
                   10037:       break;
                   10038:   }
1.201     brouard  10039:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
                   10040:     if (num_filled == 0)
                   10041:             model[0]='\0';
                   10042:     else if (num_filled != 1){
1.197     brouard  10043:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10044:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10045:       model[0]='\0';
                   10046:       goto end;
                   10047:     }
                   10048:     else{
                   10049:       if (model[0]=='+'){
                   10050:        for(i=1; i<=strlen(model);i++)
                   10051:          modeltemp[i-1]=model[i];
1.201     brouard  10052:        strcpy(model,modeltemp); 
1.197     brouard  10053:       }
                   10054:     }
1.199     brouard  10055:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  10056:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  10057:   }
                   10058:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   10059:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   10060:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  10061:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   10062:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  10063:   fflush(ficlog);
1.190     brouard  10064:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   10065:   if(model[0]=='#'){
1.187     brouard  10066:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   10067:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   10068:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   10069:     if(mle != -1){
                   10070:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   10071:       exit(1);
                   10072:     }
                   10073:   }
1.126     brouard  10074:   while((c=getc(ficpar))=='#' && c!= EOF){
                   10075:     ungetc(c,ficpar);
                   10076:     fgets(line, MAXLINE, ficpar);
                   10077:     numlinepar++;
1.195     brouard  10078:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   10079:       z[0]=line[1];
                   10080:     }
                   10081:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  10082:     fputs(line, stdout);
                   10083:     //puts(line);
1.126     brouard  10084:     fputs(line,ficparo);
                   10085:     fputs(line,ficlog);
                   10086:   }
                   10087:   ungetc(c,ficpar);
                   10088: 
                   10089:    
1.145     brouard  10090:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.225     brouard  10091:   coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
1.233     brouard  10092:   cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.225     brouard  10093:   cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
1.136     brouard  10094:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   10095:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   10096:      v1+v2*age+v2*v3 makes cptcovn = 3
                   10097:   */
                   10098:   if (strlen(model)>1) 
1.187     brouard  10099:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  10100:   else
1.187     brouard  10101:     ncovmodel=2; /* Constant and age */
1.133     brouard  10102:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   10103:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  10104:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   10105:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10106:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10107:     fflush(stdout);
                   10108:     fclose (ficlog);
                   10109:     goto end;
                   10110:   }
1.126     brouard  10111:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10112:   delti=delti3[1][1];
                   10113:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   10114:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  10115: /* We could also provide initial parameters values giving by simple logistic regression 
                   10116:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   10117:       /* for(i=1;i<nlstate;i++){ */
                   10118:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10119:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10120:       /* } */
1.126     brouard  10121:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  10122:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   10123:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10124:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   10125:     fclose (ficparo);
                   10126:     fclose (ficlog);
                   10127:     goto end;
                   10128:     exit(0);
1.220     brouard  10129:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  10130:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  10131:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   10132:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10133:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10134:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10135:     hess=matrix(1,npar,1,npar);
1.220     brouard  10136:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  10137:     /* Read guessed parameters */
1.126     brouard  10138:     /* Reads comments: lines beginning with '#' */
                   10139:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10140:       ungetc(c,ficpar);
                   10141:       fgets(line, MAXLINE, ficpar);
                   10142:       numlinepar++;
1.141     brouard  10143:       fputs(line,stdout);
1.126     brouard  10144:       fputs(line,ficparo);
                   10145:       fputs(line,ficlog);
                   10146:     }
                   10147:     ungetc(c,ficpar);
                   10148:     
                   10149:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  10150:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  10151:     for(i=1; i <=nlstate; i++){
1.234     brouard  10152:       j=0;
1.126     brouard  10153:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  10154:        if(jj==i) continue;
                   10155:        j++;
                   10156:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10157:        if ((i1 != i) || (j1 != jj)){
                   10158:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  10159: It might be a problem of design; if ncovcol and the model are correct\n \
                   10160: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  10161:          exit(1);
                   10162:        }
                   10163:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10164:        if(mle==1)
                   10165:          printf("%1d%1d",i,jj);
                   10166:        fprintf(ficlog,"%1d%1d",i,jj);
                   10167:        for(k=1; k<=ncovmodel;k++){
                   10168:          fscanf(ficpar," %lf",&param[i][j][k]);
                   10169:          if(mle==1){
                   10170:            printf(" %lf",param[i][j][k]);
                   10171:            fprintf(ficlog," %lf",param[i][j][k]);
                   10172:          }
                   10173:          else
                   10174:            fprintf(ficlog," %lf",param[i][j][k]);
                   10175:          fprintf(ficparo," %lf",param[i][j][k]);
                   10176:        }
                   10177:        fscanf(ficpar,"\n");
                   10178:        numlinepar++;
                   10179:        if(mle==1)
                   10180:          printf("\n");
                   10181:        fprintf(ficlog,"\n");
                   10182:        fprintf(ficparo,"\n");
1.126     brouard  10183:       }
                   10184:     }  
                   10185:     fflush(ficlog);
1.234     brouard  10186:     
1.251     brouard  10187:     /* Reads parameters values */
1.126     brouard  10188:     p=param[1][1];
1.251     brouard  10189:     pstart=paramstart[1][1];
1.126     brouard  10190:     
                   10191:     /* Reads comments: lines beginning with '#' */
                   10192:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10193:       ungetc(c,ficpar);
                   10194:       fgets(line, MAXLINE, ficpar);
                   10195:       numlinepar++;
1.141     brouard  10196:       fputs(line,stdout);
1.126     brouard  10197:       fputs(line,ficparo);
                   10198:       fputs(line,ficlog);
                   10199:     }
                   10200:     ungetc(c,ficpar);
                   10201: 
                   10202:     for(i=1; i <=nlstate; i++){
                   10203:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  10204:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10205:        if ( (i1-i) * (j1-j) != 0){
                   10206:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   10207:          exit(1);
                   10208:        }
                   10209:        printf("%1d%1d",i,j);
                   10210:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10211:        fprintf(ficlog,"%1d%1d",i1,j1);
                   10212:        for(k=1; k<=ncovmodel;k++){
                   10213:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   10214:          printf(" %le",delti3[i][j][k]);
                   10215:          fprintf(ficparo," %le",delti3[i][j][k]);
                   10216:          fprintf(ficlog," %le",delti3[i][j][k]);
                   10217:        }
                   10218:        fscanf(ficpar,"\n");
                   10219:        numlinepar++;
                   10220:        printf("\n");
                   10221:        fprintf(ficparo,"\n");
                   10222:        fprintf(ficlog,"\n");
1.126     brouard  10223:       }
                   10224:     }
                   10225:     fflush(ficlog);
1.234     brouard  10226:     
1.145     brouard  10227:     /* Reads covariance matrix */
1.126     brouard  10228:     delti=delti3[1][1];
1.220     brouard  10229:                
                   10230:                
1.126     brouard  10231:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  10232:                
1.126     brouard  10233:     /* Reads comments: lines beginning with '#' */
                   10234:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10235:       ungetc(c,ficpar);
                   10236:       fgets(line, MAXLINE, ficpar);
                   10237:       numlinepar++;
1.141     brouard  10238:       fputs(line,stdout);
1.126     brouard  10239:       fputs(line,ficparo);
                   10240:       fputs(line,ficlog);
                   10241:     }
                   10242:     ungetc(c,ficpar);
1.220     brouard  10243:                
1.126     brouard  10244:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10245:     hess=matrix(1,npar,1,npar);
1.131     brouard  10246:     for(i=1; i <=npar; i++)
                   10247:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  10248:                
1.194     brouard  10249:     /* Scans npar lines */
1.126     brouard  10250:     for(i=1; i <=npar; i++){
1.226     brouard  10251:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  10252:       if(count != 3){
1.226     brouard  10253:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10254: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10255: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10256:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10257: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10258: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10259:        exit(1);
1.220     brouard  10260:       }else{
1.226     brouard  10261:        if(mle==1)
                   10262:          printf("%1d%1d%d",i1,j1,jk);
                   10263:       }
                   10264:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   10265:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  10266:       for(j=1; j <=i; j++){
1.226     brouard  10267:        fscanf(ficpar," %le",&matcov[i][j]);
                   10268:        if(mle==1){
                   10269:          printf(" %.5le",matcov[i][j]);
                   10270:        }
                   10271:        fprintf(ficlog," %.5le",matcov[i][j]);
                   10272:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  10273:       }
                   10274:       fscanf(ficpar,"\n");
                   10275:       numlinepar++;
                   10276:       if(mle==1)
1.220     brouard  10277:                                printf("\n");
1.126     brouard  10278:       fprintf(ficlog,"\n");
                   10279:       fprintf(ficparo,"\n");
                   10280:     }
1.194     brouard  10281:     /* End of read covariance matrix npar lines */
1.126     brouard  10282:     for(i=1; i <=npar; i++)
                   10283:       for(j=i+1;j<=npar;j++)
1.226     brouard  10284:        matcov[i][j]=matcov[j][i];
1.126     brouard  10285:     
                   10286:     if(mle==1)
                   10287:       printf("\n");
                   10288:     fprintf(ficlog,"\n");
                   10289:     
                   10290:     fflush(ficlog);
                   10291:     
                   10292:     /*-------- Rewriting parameter file ----------*/
                   10293:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   10294:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   10295:     strcat(rfileres,".");    /* */
                   10296:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10297:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  10298:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10299:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  10300:     }
                   10301:     fprintf(ficres,"#%s\n",version);
                   10302:   }    /* End of mle != -3 */
1.218     brouard  10303:   
1.186     brouard  10304:   /*  Main data
                   10305:    */
1.126     brouard  10306:   n= lastobs;
                   10307:   num=lvector(1,n);
                   10308:   moisnais=vector(1,n);
                   10309:   annais=vector(1,n);
                   10310:   moisdc=vector(1,n);
                   10311:   andc=vector(1,n);
1.220     brouard  10312:   weight=vector(1,n);
1.126     brouard  10313:   agedc=vector(1,n);
                   10314:   cod=ivector(1,n);
1.220     brouard  10315:   for(i=1;i<=n;i++){
1.234     brouard  10316:     num[i]=0;
                   10317:     moisnais[i]=0;
                   10318:     annais[i]=0;
                   10319:     moisdc[i]=0;
                   10320:     andc[i]=0;
                   10321:     agedc[i]=0;
                   10322:     cod[i]=0;
                   10323:     weight[i]=1.0; /* Equal weights, 1 by default */
                   10324:   }
1.126     brouard  10325:   mint=matrix(1,maxwav,1,n);
                   10326:   anint=matrix(1,maxwav,1,n);
1.131     brouard  10327:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  10328:   tab=ivector(1,NCOVMAX);
1.144     brouard  10329:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  10330:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  10331: 
1.136     brouard  10332:   /* Reads data from file datafile */
                   10333:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   10334:     goto end;
                   10335: 
                   10336:   /* Calculation of the number of parameters from char model */
1.234     brouard  10337:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  10338:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   10339:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   10340:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   10341:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  10342:   */
                   10343:   
                   10344:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   10345:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   10346:   TvarsD=ivector(1,NCOVMAX); /*  */
                   10347:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   10348:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  10349:   TvarF=ivector(1,NCOVMAX); /*  */
                   10350:   TvarFind=ivector(1,NCOVMAX); /*  */
                   10351:   TvarV=ivector(1,NCOVMAX); /*  */
                   10352:   TvarVind=ivector(1,NCOVMAX); /*  */
                   10353:   TvarA=ivector(1,NCOVMAX); /*  */
                   10354:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  10355:   TvarFD=ivector(1,NCOVMAX); /*  */
                   10356:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   10357:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   10358:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   10359:   TvarVD=ivector(1,NCOVMAX); /*  */
                   10360:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   10361:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   10362:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   10363: 
1.230     brouard  10364:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  10365:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  10366:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   10367:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   10368:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  10369:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   10370:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   10371:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   10372:   */
                   10373:   /* For model-covariate k tells which data-covariate to use but
                   10374:     because this model-covariate is a construction we invent a new column
                   10375:     ncovcol + k1
                   10376:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   10377:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  10378:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   10379:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  10380:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   10381:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  10382:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  10383:   */
1.145     brouard  10384:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   10385:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  10386:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   10387:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  10388:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  10389:                         4 covariates (3 plus signs)
                   10390:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   10391:                      */  
1.230     brouard  10392:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  10393:                                * individual dummy, fixed or varying:
                   10394:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   10395:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  10396:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   10397:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   10398:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   10399:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   10400:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  10401:                                * individual quantitative, fixed or varying:
                   10402:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   10403:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   10404:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  10405: /* Main decodemodel */
                   10406: 
1.187     brouard  10407: 
1.223     brouard  10408:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  10409:     goto end;
                   10410: 
1.137     brouard  10411:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   10412:     nbwarn++;
                   10413:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10414:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10415:   }
1.136     brouard  10416:     /*  if(mle==1){*/
1.137     brouard  10417:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   10418:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  10419:   }
                   10420: 
                   10421:     /*-calculation of age at interview from date of interview and age at death -*/
                   10422:   agev=matrix(1,maxwav,1,imx);
                   10423: 
                   10424:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   10425:     goto end;
                   10426: 
1.126     brouard  10427: 
1.136     brouard  10428:   agegomp=(int)agemin;
                   10429:   free_vector(moisnais,1,n);
                   10430:   free_vector(annais,1,n);
1.126     brouard  10431:   /* free_matrix(mint,1,maxwav,1,n);
                   10432:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  10433:   /* free_vector(moisdc,1,n); */
                   10434:   /* free_vector(andc,1,n); */
1.145     brouard  10435:   /* */
                   10436:   
1.126     brouard  10437:   wav=ivector(1,imx);
1.214     brouard  10438:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10439:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10440:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10441:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   10442:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   10443:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  10444:    
                   10445:   /* Concatenates waves */
1.214     brouard  10446:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   10447:      Death is a valid wave (if date is known).
                   10448:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   10449:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   10450:      and mw[mi+1][i]. dh depends on stepm.
                   10451:   */
                   10452: 
1.126     brouard  10453:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  10454:   /* Concatenates waves */
1.145     brouard  10455:  
1.215     brouard  10456:   free_vector(moisdc,1,n);
                   10457:   free_vector(andc,1,n);
                   10458: 
1.126     brouard  10459:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   10460:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   10461:   ncodemax[1]=1;
1.145     brouard  10462:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  10463:   cptcoveff=0;
1.220     brouard  10464:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   10465:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  10466:   }
                   10467:   
                   10468:   ncovcombmax=pow(2,cptcoveff);
                   10469:   invalidvarcomb=ivector(1, ncovcombmax); 
                   10470:   for(i=1;i<ncovcombmax;i++)
                   10471:     invalidvarcomb[i]=0;
                   10472:   
1.211     brouard  10473:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  10474:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  10475:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  10476:   
1.200     brouard  10477:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  10478:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  10479:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  10480:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   10481:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   10482:    * (currently 0 or 1) in the data.
                   10483:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   10484:    * corresponding modality (h,j).
                   10485:    */
                   10486: 
1.145     brouard  10487:   h=0;
                   10488:   /*if (cptcovn > 0) */
1.126     brouard  10489:   m=pow(2,cptcoveff);
                   10490:  
1.144     brouard  10491:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  10492:           * For k=4 covariates, h goes from 1 to m=2**k
                   10493:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   10494:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  10495:           *     h\k   1     2     3     4
1.143     brouard  10496:           *______________________________  
                   10497:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   10498:           *     2     2     1     1     1
                   10499:           *     3 i=2 1     2     1     1
                   10500:           *     4     2     2     1     1
                   10501:           *     5 i=3 1 i=2 1     2     1
                   10502:           *     6     2     1     2     1
                   10503:           *     7 i=4 1     2     2     1
                   10504:           *     8     2     2     2     1
1.197     brouard  10505:           *     9 i=5 1 i=3 1 i=2 1     2
                   10506:           *    10     2     1     1     2
                   10507:           *    11 i=6 1     2     1     2
                   10508:           *    12     2     2     1     2
                   10509:           *    13 i=7 1 i=4 1     2     2    
                   10510:           *    14     2     1     2     2
                   10511:           *    15 i=8 1     2     2     2
                   10512:           *    16     2     2     2     2
1.143     brouard  10513:           */
1.212     brouard  10514:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  10515:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   10516:      * and the value of each covariate?
                   10517:      * V1=1, V2=1, V3=2, V4=1 ?
                   10518:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   10519:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   10520:      * In order to get the real value in the data, we use nbcode
                   10521:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   10522:      * We are keeping this crazy system in order to be able (in the future?) 
                   10523:      * to have more than 2 values (0 or 1) for a covariate.
                   10524:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   10525:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   10526:      *              bbbbbbbb
                   10527:      *              76543210     
                   10528:      *   h-1        00000101 (6-1=5)
1.219     brouard  10529:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  10530:      *           &
                   10531:      *     1        00000001 (1)
1.219     brouard  10532:      *              00000000        = 1 & ((h-1) >> (k-1))
                   10533:      *          +1= 00000001 =1 
1.211     brouard  10534:      *
                   10535:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   10536:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   10537:      *    >>k'            11
                   10538:      *          &   00000001
                   10539:      *            = 00000001
                   10540:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   10541:      * Reverse h=6 and m=16?
                   10542:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   10543:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   10544:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   10545:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   10546:      * V3=decodtabm(14,3,2**4)=2
                   10547:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   10548:      *(h-1) >> (j-1)    0011 =13 >> 2
                   10549:      *          &1 000000001
                   10550:      *           = 000000001
                   10551:      *         +1= 000000010 =2
                   10552:      *                  2211
                   10553:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   10554:      *                  V3=2
1.220     brouard  10555:                 * codtabm and decodtabm are identical
1.211     brouard  10556:      */
                   10557: 
1.145     brouard  10558: 
                   10559:  free_ivector(Ndum,-1,NCOVMAX);
                   10560: 
                   10561: 
1.126     brouard  10562:     
1.186     brouard  10563:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  10564:   strcpy(optionfilegnuplot,optionfilefiname);
                   10565:   if(mle==-3)
1.201     brouard  10566:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  10567:   strcat(optionfilegnuplot,".gp");
                   10568: 
                   10569:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   10570:     printf("Problem with file %s",optionfilegnuplot);
                   10571:   }
                   10572:   else{
1.204     brouard  10573:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  10574:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  10575:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   10576:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  10577:   }
                   10578:   /*  fclose(ficgp);*/
1.186     brouard  10579: 
                   10580: 
                   10581:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  10582: 
                   10583:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   10584:   if(mle==-3)
1.201     brouard  10585:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  10586:   strcat(optionfilehtm,".htm");
                   10587:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  10588:     printf("Problem with %s \n",optionfilehtm);
                   10589:     exit(0);
1.126     brouard  10590:   }
                   10591: 
                   10592:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   10593:   strcat(optionfilehtmcov,"-cov.htm");
                   10594:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   10595:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   10596:   }
                   10597:   else{
                   10598:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   10599: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10600: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  10601:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   10602:   }
                   10603: 
1.213     brouard  10604:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  10605: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   10606: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  10607: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10608: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  10609: \n\
                   10610: <hr  size=\"2\" color=\"#EC5E5E\">\
                   10611:  <ul><li><h4>Parameter files</h4>\n\
                   10612:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   10613:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   10614:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   10615:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   10616:  - Date and time at start: %s</ul>\n",\
                   10617:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   10618:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   10619:          fileres,fileres,\
                   10620:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   10621:   fflush(fichtm);
                   10622: 
                   10623:   strcpy(pathr,path);
                   10624:   strcat(pathr,optionfilefiname);
1.184     brouard  10625: #ifdef WIN32
                   10626:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   10627: #else
1.126     brouard  10628:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  10629: #endif
                   10630:          
1.126     brouard  10631:   
1.220     brouard  10632:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   10633:                 and for any valid combination of covariates
1.126     brouard  10634:      and prints on file fileres'p'. */
1.251     brouard  10635:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  10636:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  10637: 
                   10638:   fprintf(fichtm,"\n");
                   10639:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   10640: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   10641: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   10642:          imx,agemin,agemax,jmin,jmax,jmean);
                   10643:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.220     brouard  10644:        oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10645:        newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10646:        savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10647:        oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  10648: 
1.126     brouard  10649:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   10650:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   10651:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   10652: 
                   10653:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  10654:   /* For mortality only */
1.126     brouard  10655:   if (mle==-3){
1.136     brouard  10656:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  10657:     for(i=1;i<=NDIM;i++)
                   10658:       for(j=1;j<=NDIM;j++)
                   10659:        ximort[i][j]=0.;
1.186     brouard  10660:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  10661:     cens=ivector(1,n);
                   10662:     ageexmed=vector(1,n);
                   10663:     agecens=vector(1,n);
                   10664:     dcwave=ivector(1,n);
1.223     brouard  10665:                
1.126     brouard  10666:     for (i=1; i<=imx; i++){
                   10667:       dcwave[i]=-1;
                   10668:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  10669:        if (s[m][i]>nlstate) {
                   10670:          dcwave[i]=m;
                   10671:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   10672:          break;
                   10673:        }
1.126     brouard  10674:     }
1.226     brouard  10675:     
1.126     brouard  10676:     for (i=1; i<=imx; i++) {
                   10677:       if (wav[i]>0){
1.226     brouard  10678:        ageexmed[i]=agev[mw[1][i]][i];
                   10679:        j=wav[i];
                   10680:        agecens[i]=1.; 
                   10681:        
                   10682:        if (ageexmed[i]> 1 && wav[i] > 0){
                   10683:          agecens[i]=agev[mw[j][i]][i];
                   10684:          cens[i]= 1;
                   10685:        }else if (ageexmed[i]< 1) 
                   10686:          cens[i]= -1;
                   10687:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   10688:          cens[i]=0 ;
1.126     brouard  10689:       }
                   10690:       else cens[i]=-1;
                   10691:     }
                   10692:     
                   10693:     for (i=1;i<=NDIM;i++) {
                   10694:       for (j=1;j<=NDIM;j++)
1.226     brouard  10695:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  10696:     }
                   10697:     
1.145     brouard  10698:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  10699:     /*printf("%lf %lf", p[1], p[2]);*/
                   10700:     
                   10701:     
1.136     brouard  10702: #ifdef GSL
                   10703:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  10704: #else
1.126     brouard  10705:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  10706: #endif
1.201     brouard  10707:     strcpy(filerespow,"POW-MORT_"); 
                   10708:     strcat(filerespow,fileresu);
1.126     brouard  10709:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   10710:       printf("Problem with resultfile: %s\n", filerespow);
                   10711:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   10712:     }
1.136     brouard  10713: #ifdef GSL
                   10714:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  10715: #else
1.126     brouard  10716:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  10717: #endif
1.126     brouard  10718:     /*  for (i=1;i<=nlstate;i++)
                   10719:        for(j=1;j<=nlstate+ndeath;j++)
                   10720:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   10721:     */
                   10722:     fprintf(ficrespow,"\n");
1.136     brouard  10723: #ifdef GSL
                   10724:     /* gsl starts here */ 
                   10725:     T = gsl_multimin_fminimizer_nmsimplex;
                   10726:     gsl_multimin_fminimizer *sfm = NULL;
                   10727:     gsl_vector *ss, *x;
                   10728:     gsl_multimin_function minex_func;
                   10729: 
                   10730:     /* Initial vertex size vector */
                   10731:     ss = gsl_vector_alloc (NDIM);
                   10732:     
                   10733:     if (ss == NULL){
                   10734:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   10735:     }
                   10736:     /* Set all step sizes to 1 */
                   10737:     gsl_vector_set_all (ss, 0.001);
                   10738: 
                   10739:     /* Starting point */
1.126     brouard  10740:     
1.136     brouard  10741:     x = gsl_vector_alloc (NDIM);
                   10742:     
                   10743:     if (x == NULL){
                   10744:       gsl_vector_free(ss);
                   10745:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   10746:     }
                   10747:   
                   10748:     /* Initialize method and iterate */
                   10749:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  10750:     /*     gsl_vector_set(x, 0, 0.0268); */
                   10751:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  10752:     gsl_vector_set(x, 0, p[1]);
                   10753:     gsl_vector_set(x, 1, p[2]);
                   10754: 
                   10755:     minex_func.f = &gompertz_f;
                   10756:     minex_func.n = NDIM;
                   10757:     minex_func.params = (void *)&p; /* ??? */
                   10758:     
                   10759:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   10760:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   10761:     
                   10762:     printf("Iterations beginning .....\n\n");
                   10763:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   10764: 
                   10765:     iteri=0;
                   10766:     while (rval == GSL_CONTINUE){
                   10767:       iteri++;
                   10768:       status = gsl_multimin_fminimizer_iterate(sfm);
                   10769:       
                   10770:       if (status) printf("error: %s\n", gsl_strerror (status));
                   10771:       fflush(0);
                   10772:       
                   10773:       if (status) 
                   10774:         break;
                   10775:       
                   10776:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   10777:       ssval = gsl_multimin_fminimizer_size (sfm);
                   10778:       
                   10779:       if (rval == GSL_SUCCESS)
                   10780:         printf ("converged to a local maximum at\n");
                   10781:       
                   10782:       printf("%5d ", iteri);
                   10783:       for (it = 0; it < NDIM; it++){
                   10784:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   10785:       }
                   10786:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   10787:     }
                   10788:     
                   10789:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   10790:     
                   10791:     gsl_vector_free(x); /* initial values */
                   10792:     gsl_vector_free(ss); /* inital step size */
                   10793:     for (it=0; it<NDIM; it++){
                   10794:       p[it+1]=gsl_vector_get(sfm->x,it);
                   10795:       fprintf(ficrespow," %.12lf", p[it]);
                   10796:     }
                   10797:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   10798: #endif
                   10799: #ifdef POWELL
                   10800:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   10801: #endif  
1.126     brouard  10802:     fclose(ficrespow);
                   10803:     
1.203     brouard  10804:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  10805: 
                   10806:     for(i=1; i <=NDIM; i++)
                   10807:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  10808:                                matcov[i][j]=matcov[j][i];
1.126     brouard  10809:     
                   10810:     printf("\nCovariance matrix\n ");
1.203     brouard  10811:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  10812:     for(i=1; i <=NDIM; i++) {
                   10813:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  10814:                                printf("%f ",matcov[i][j]);
                   10815:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  10816:       }
1.203     brouard  10817:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  10818:     }
                   10819:     
                   10820:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  10821:     for (i=1;i<=NDIM;i++) {
1.126     brouard  10822:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  10823:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   10824:     }
1.126     brouard  10825:     lsurv=vector(1,AGESUP);
                   10826:     lpop=vector(1,AGESUP);
                   10827:     tpop=vector(1,AGESUP);
                   10828:     lsurv[agegomp]=100000;
                   10829:     
                   10830:     for (k=agegomp;k<=AGESUP;k++) {
                   10831:       agemortsup=k;
                   10832:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   10833:     }
                   10834:     
                   10835:     for (k=agegomp;k<agemortsup;k++)
                   10836:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   10837:     
                   10838:     for (k=agegomp;k<agemortsup;k++){
                   10839:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   10840:       sumlpop=sumlpop+lpop[k];
                   10841:     }
                   10842:     
                   10843:     tpop[agegomp]=sumlpop;
                   10844:     for (k=agegomp;k<(agemortsup-3);k++){
                   10845:       /*  tpop[k+1]=2;*/
                   10846:       tpop[k+1]=tpop[k]-lpop[k];
                   10847:     }
                   10848:     
                   10849:     
                   10850:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   10851:     for (k=agegomp;k<(agemortsup-2);k++) 
                   10852:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   10853:     
                   10854:     
                   10855:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  10856:                ageminpar=50;
                   10857:                agemaxpar=100;
1.194     brouard  10858:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   10859:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10860: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10861: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   10862:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10863: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10864: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10865:     }else{
                   10866:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   10867:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  10868:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  10869:                }
1.201     brouard  10870:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  10871:                     stepm, weightopt,\
                   10872:                     model,imx,p,matcov,agemortsup);
                   10873:     
                   10874:     free_vector(lsurv,1,AGESUP);
                   10875:     free_vector(lpop,1,AGESUP);
                   10876:     free_vector(tpop,1,AGESUP);
1.220     brouard  10877:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  10878:     free_ivector(cens,1,n);
                   10879:     free_vector(agecens,1,n);
                   10880:     free_ivector(dcwave,1,n);
1.220     brouard  10881: #ifdef GSL
1.136     brouard  10882: #endif
1.186     brouard  10883:   } /* Endof if mle==-3 mortality only */
1.205     brouard  10884:   /* Standard  */
                   10885:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   10886:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10887:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  10888:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  10889:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10890:     for (k=1; k<=npar;k++)
                   10891:       printf(" %d %8.5f",k,p[k]);
                   10892:     printf("\n");
1.205     brouard  10893:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   10894:       /* mlikeli uses func not funcone */
1.247     brouard  10895:       /* for(i=1;i<nlstate;i++){ */
                   10896:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10897:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10898:       /* } */
1.205     brouard  10899:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   10900:     }
                   10901:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   10902:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10903:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   10904:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10905:     }
                   10906:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  10907:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10908:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10909:     for (k=1; k<=npar;k++)
                   10910:       printf(" %d %8.5f",k,p[k]);
                   10911:     printf("\n");
                   10912:     
                   10913:     /*--------- results files --------------*/
1.224     brouard  10914:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  10915:     
                   10916:     
                   10917:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10918:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10919:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10920:     for(i=1,jk=1; i <=nlstate; i++){
                   10921:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  10922:        if (k != i) {
                   10923:          printf("%d%d ",i,k);
                   10924:          fprintf(ficlog,"%d%d ",i,k);
                   10925:          fprintf(ficres,"%1d%1d ",i,k);
                   10926:          for(j=1; j <=ncovmodel; j++){
                   10927:            printf("%12.7f ",p[jk]);
                   10928:            fprintf(ficlog,"%12.7f ",p[jk]);
                   10929:            fprintf(ficres,"%12.7f ",p[jk]);
                   10930:            jk++; 
                   10931:          }
                   10932:          printf("\n");
                   10933:          fprintf(ficlog,"\n");
                   10934:          fprintf(ficres,"\n");
                   10935:        }
1.126     brouard  10936:       }
                   10937:     }
1.203     brouard  10938:     if(mle != 0){
                   10939:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  10940:       ftolhess=ftol; /* Usually correct */
1.203     brouard  10941:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   10942:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10943:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10944:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  10945:        for(k=1; k <=(nlstate+ndeath); k++){
                   10946:          if (k != i) {
                   10947:            printf("%d%d ",i,k);
                   10948:            fprintf(ficlog,"%d%d ",i,k);
                   10949:            for(j=1; j <=ncovmodel; j++){
                   10950:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10951:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10952:              jk++; 
                   10953:            }
                   10954:            printf("\n");
                   10955:            fprintf(ficlog,"\n");
                   10956:          }
                   10957:        }
1.193     brouard  10958:       }
1.203     brouard  10959:     } /* end of hesscov and Wald tests */
1.225     brouard  10960:     
1.203     brouard  10961:     /*  */
1.126     brouard  10962:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   10963:     printf("# Scales (for hessian or gradient estimation)\n");
                   10964:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   10965:     for(i=1,jk=1; i <=nlstate; i++){
                   10966:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  10967:        if (j!=i) {
                   10968:          fprintf(ficres,"%1d%1d",i,j);
                   10969:          printf("%1d%1d",i,j);
                   10970:          fprintf(ficlog,"%1d%1d",i,j);
                   10971:          for(k=1; k<=ncovmodel;k++){
                   10972:            printf(" %.5e",delti[jk]);
                   10973:            fprintf(ficlog," %.5e",delti[jk]);
                   10974:            fprintf(ficres," %.5e",delti[jk]);
                   10975:            jk++;
                   10976:          }
                   10977:          printf("\n");
                   10978:          fprintf(ficlog,"\n");
                   10979:          fprintf(ficres,"\n");
                   10980:        }
1.126     brouard  10981:       }
                   10982:     }
                   10983:     
                   10984:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  10985:     if(mle >= 1) /* To big for the screen */
1.126     brouard  10986:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   10987:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   10988:     /* # 121 Var(a12)\n\ */
                   10989:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   10990:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   10991:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   10992:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   10993:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   10994:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   10995:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   10996:     
                   10997:     
                   10998:     /* Just to have a covariance matrix which will be more understandable
                   10999:        even is we still don't want to manage dictionary of variables
                   11000:     */
                   11001:     for(itimes=1;itimes<=2;itimes++){
                   11002:       jj=0;
                   11003:       for(i=1; i <=nlstate; i++){
1.225     brouard  11004:        for(j=1; j <=nlstate+ndeath; j++){
                   11005:          if(j==i) continue;
                   11006:          for(k=1; k<=ncovmodel;k++){
                   11007:            jj++;
                   11008:            ca[0]= k+'a'-1;ca[1]='\0';
                   11009:            if(itimes==1){
                   11010:              if(mle>=1)
                   11011:                printf("#%1d%1d%d",i,j,k);
                   11012:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   11013:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   11014:            }else{
                   11015:              if(mle>=1)
                   11016:                printf("%1d%1d%d",i,j,k);
                   11017:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   11018:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   11019:            }
                   11020:            ll=0;
                   11021:            for(li=1;li <=nlstate; li++){
                   11022:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   11023:                if(lj==li) continue;
                   11024:                for(lk=1;lk<=ncovmodel;lk++){
                   11025:                  ll++;
                   11026:                  if(ll<=jj){
                   11027:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   11028:                    if(ll<jj){
                   11029:                      if(itimes==1){
                   11030:                        if(mle>=1)
                   11031:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11032:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11033:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11034:                      }else{
                   11035:                        if(mle>=1)
                   11036:                          printf(" %.5e",matcov[jj][ll]); 
                   11037:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   11038:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   11039:                      }
                   11040:                    }else{
                   11041:                      if(itimes==1){
                   11042:                        if(mle>=1)
                   11043:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   11044:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   11045:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   11046:                      }else{
                   11047:                        if(mle>=1)
                   11048:                          printf(" %.7e",matcov[jj][ll]); 
                   11049:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   11050:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   11051:                      }
                   11052:                    }
                   11053:                  }
                   11054:                } /* end lk */
                   11055:              } /* end lj */
                   11056:            } /* end li */
                   11057:            if(mle>=1)
                   11058:              printf("\n");
                   11059:            fprintf(ficlog,"\n");
                   11060:            fprintf(ficres,"\n");
                   11061:            numlinepar++;
                   11062:          } /* end k*/
                   11063:        } /*end j */
1.126     brouard  11064:       } /* end i */
                   11065:     } /* end itimes */
                   11066:     
                   11067:     fflush(ficlog);
                   11068:     fflush(ficres);
1.225     brouard  11069:     while(fgets(line, MAXLINE, ficpar)) {
                   11070:       /* If line starts with a # it is a comment */
                   11071:       if (line[0] == '#') {
                   11072:        numlinepar++;
                   11073:        fputs(line,stdout);
                   11074:        fputs(line,ficparo);
                   11075:        fputs(line,ficlog);
                   11076:        continue;
                   11077:       }else
                   11078:        break;
                   11079:     }
                   11080:     
1.209     brouard  11081:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11082:     /*   ungetc(c,ficpar); */
                   11083:     /*   fgets(line, MAXLINE, ficpar); */
                   11084:     /*   fputs(line,stdout); */
                   11085:     /*   fputs(line,ficparo); */
                   11086:     /* } */
                   11087:     /* ungetc(c,ficpar); */
1.126     brouard  11088:     
                   11089:     estepm=0;
1.209     brouard  11090:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  11091:       
                   11092:       if (num_filled != 6) {
                   11093:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11094:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11095:        goto end;
                   11096:       }
                   11097:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   11098:     }
                   11099:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   11100:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   11101:     
1.209     brouard  11102:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  11103:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   11104:     if (fage <= 2) {
                   11105:       bage = ageminpar;
                   11106:       fage = agemaxpar;
                   11107:     }
                   11108:     
                   11109:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  11110:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   11111:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  11112:                
1.186     brouard  11113:     /* Other stuffs, more or less useful */    
1.126     brouard  11114:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11115:       ungetc(c,ficpar);
                   11116:       fgets(line, MAXLINE, ficpar);
1.141     brouard  11117:       fputs(line,stdout);
1.126     brouard  11118:       fputs(line,ficparo);
                   11119:     }
                   11120:     ungetc(c,ficpar);
                   11121:     
                   11122:     fscanf(ficpar,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav);
                   11123:     fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11124:     fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11125:     printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11126:     fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11127:     
                   11128:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11129:       ungetc(c,ficpar);
                   11130:       fgets(line, MAXLINE, ficpar);
1.141     brouard  11131:       fputs(line,stdout);
1.126     brouard  11132:       fputs(line,ficparo);
                   11133:     }
                   11134:     ungetc(c,ficpar);
                   11135:     
                   11136:     
                   11137:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   11138:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   11139:     
                   11140:     fscanf(ficpar,"pop_based=%d\n",&popbased);
1.193     brouard  11141:     fprintf(ficlog,"pop_based=%d\n",popbased);
1.126     brouard  11142:     fprintf(ficparo,"pop_based=%d\n",popbased);   
                   11143:     fprintf(ficres,"pop_based=%d\n",popbased);   
                   11144:     
                   11145:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11146:       ungetc(c,ficpar);
                   11147:       fgets(line, MAXLINE, ficpar);
1.141     brouard  11148:       fputs(line,stdout);
1.238     brouard  11149:       fputs(line,ficres);
1.126     brouard  11150:       fputs(line,ficparo);
                   11151:     }
                   11152:     ungetc(c,ficpar);
                   11153:     
                   11154:     fscanf(ficpar,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj);
                   11155:     fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11156:     printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11157:     fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11158:     fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11159:     /* day and month of proj2 are not used but only year anproj2.*/
                   11160:     
1.217     brouard  11161:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11162:       ungetc(c,ficpar);
                   11163:       fgets(line, MAXLINE, ficpar);
                   11164:       fputs(line,stdout);
                   11165:       fputs(line,ficparo);
1.238     brouard  11166:       fputs(line,ficres);
1.217     brouard  11167:     }
                   11168:     ungetc(c,ficpar);
                   11169:     
                   11170:     fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);
1.223     brouard  11171:     fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11172:     fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11173:     fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
1.217     brouard  11174:     /* day and month of proj2 are not used but only year anproj2.*/
1.126     brouard  11175:     
1.230     brouard  11176:     /* Results */
1.235     brouard  11177:     nresult=0;
1.230     brouard  11178:     while(fgets(line, MAXLINE, ficpar)) {
                   11179:       /* If line starts with a # it is a comment */
                   11180:       if (line[0] == '#') {
                   11181:        numlinepar++;
                   11182:        fputs(line,stdout);
                   11183:        fputs(line,ficparo);
                   11184:        fputs(line,ficlog);
1.238     brouard  11185:        fputs(line,ficres);
1.230     brouard  11186:        continue;
                   11187:       }else
                   11188:        break;
                   11189:     }
1.240     brouard  11190:     if (!feof(ficpar))
1.230     brouard  11191:     while((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
1.240     brouard  11192:       if (num_filled == 0){
1.230     brouard  11193:        resultline[0]='\0';
1.253   ! brouard  11194:        printf("Warning %d: no result line should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
1.240     brouard  11195:       break;
                   11196:       } else if (num_filled != 1){
1.253   ! brouard  11197:        printf("ERROR %d: result line should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
1.230     brouard  11198:       }
1.235     brouard  11199:       nresult++; /* Sum of resultlines */
                   11200:       printf("Result %d: result=%s\n",nresult, resultline);
                   11201:       if(nresult > MAXRESULTLINES){
                   11202:        printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11203:        fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11204:        goto end;
                   11205:       }
                   11206:       decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
1.238     brouard  11207:       fprintf(ficparo,"result: %s\n",resultline);
                   11208:       fprintf(ficres,"result: %s\n",resultline);
                   11209:       fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  11210:       while(fgets(line, MAXLINE, ficpar)) {
                   11211:        /* If line starts with a # it is a comment */
                   11212:        if (line[0] == '#') {
                   11213:          numlinepar++;
                   11214:          fputs(line,stdout);
                   11215:          fputs(line,ficparo);
1.238     brouard  11216:          fputs(line,ficres);
1.230     brouard  11217:          fputs(line,ficlog);
                   11218:          continue;
                   11219:        }else
                   11220:          break;
                   11221:       }
                   11222:       if (feof(ficpar))
                   11223:        break;
                   11224:       else{ /* Processess output results for this combination of covariate values */
                   11225:       }                                   
1.240     brouard  11226:     } /* end while */
1.230     brouard  11227: 
                   11228: 
1.126     brouard  11229:     
1.230     brouard  11230:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  11231:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  11232:     
                   11233:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  11234:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  11235:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11236: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11237: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  11238:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11239: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11240: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11241:     }else{
1.218     brouard  11242:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p);
1.220     brouard  11243:     }
                   11244:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.225     brouard  11245:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,prevfcast,backcast, estepm, \
                   11246:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  11247:                
1.225     brouard  11248:     /*------------ free_vector  -------------*/
                   11249:     /*  chdir(path); */
1.220     brouard  11250:                
1.215     brouard  11251:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   11252:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   11253:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   11254:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  11255:     free_lvector(num,1,n);
                   11256:     free_vector(agedc,1,n);
                   11257:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   11258:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   11259:     fclose(ficparo);
                   11260:     fclose(ficres);
1.220     brouard  11261:                
                   11262:                
1.186     brouard  11263:     /* Other results (useful)*/
1.220     brouard  11264:                
                   11265:                
1.126     brouard  11266:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  11267:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   11268:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  11269:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  11270:     fclose(ficrespl);
                   11271: 
                   11272:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  11273:     /*#include "hpijx.h"*/
                   11274:     hPijx(p, bage, fage);
1.145     brouard  11275:     fclose(ficrespij);
1.227     brouard  11276:     
1.220     brouard  11277:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  11278:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  11279:     k=1;
1.126     brouard  11280:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  11281:     
1.219     brouard  11282:     /* Prevalence for each covariates in probs[age][status][cov] */
1.218     brouard  11283:     probs= ma3x(1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.126     brouard  11284:     for(i=1;i<=AGESUP;i++)
1.219     brouard  11285:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  11286:        for(k=1;k<=ncovcombmax;k++)
                   11287:          probs[i][j][k]=0.;
1.219     brouard  11288:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
                   11289:     if (mobilav!=0 ||mobilavproj !=0 ) {
                   11290:       mobaverages= ma3x(1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.227     brouard  11291:       for(i=1;i<=AGESUP;i++)
                   11292:        for(j=1;j<=nlstate;j++)
                   11293:          for(k=1;k<=ncovcombmax;k++)
                   11294:            mobaverages[i][j][k]=0.;
1.219     brouard  11295:       mobaverage=mobaverages;
                   11296:       if (mobilav!=0) {
1.235     brouard  11297:        printf("Movingaveraging observed prevalence\n");
1.227     brouard  11298:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   11299:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   11300:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   11301:        }
1.219     brouard  11302:       }
                   11303:       /* /\* Prevalence for each covariates in probs[age][status][cov] *\/ */
                   11304:       /* prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   11305:       else if (mobilavproj !=0) {
1.235     brouard  11306:        printf("Movingaveraging projected observed prevalence\n");
1.227     brouard  11307:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   11308:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11309:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11310:        }
1.219     brouard  11311:       }
                   11312:     }/* end if moving average */
1.227     brouard  11313:     
1.126     brouard  11314:     /*---------- Forecasting ------------------*/
                   11315:     /*if((stepm == 1) && (strcmp(model,".")==0)){*/
                   11316:     if(prevfcast==1){
                   11317:       /*    if(stepm ==1){*/
1.225     brouard  11318:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  11319:     }
1.217     brouard  11320:     if(backcast==1){
1.219     brouard  11321:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11322:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11323:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   11324: 
                   11325:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   11326: 
                   11327:       bprlim=matrix(1,nlstate,1,nlstate);
                   11328:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   11329:       fclose(ficresplb);
                   11330: 
1.222     brouard  11331:       hBijx(p, bage, fage, mobaverage);
                   11332:       fclose(ficrespijb);
1.219     brouard  11333:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11334: 
                   11335:       /* prevbackforecast(fileresu, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, mobilavproj,
1.225     brouard  11336:         bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
1.219     brouard  11337:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11338:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11339:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11340:     }
1.217     brouard  11341:     
1.186     brouard  11342:  
                   11343:     /* ------ Other prevalence ratios------------ */
1.126     brouard  11344: 
1.215     brouard  11345:     free_ivector(wav,1,imx);
                   11346:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   11347:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   11348:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  11349:                
                   11350:                
1.127     brouard  11351:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  11352:                
1.201     brouard  11353:     strcpy(filerese,"E_");
                   11354:     strcat(filerese,fileresu);
1.126     brouard  11355:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   11356:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11357:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11358:     }
1.208     brouard  11359:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   11360:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  11361: 
                   11362:     pstamp(ficreseij);
1.219     brouard  11363:                
1.235     brouard  11364:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11365:     if (cptcovn < 1){i1=1;}
                   11366:     
                   11367:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11368:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253   ! brouard  11369:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11370:        continue;
1.219     brouard  11371:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  11372:       printf("\n#****** ");
1.225     brouard  11373:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11374:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11375:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11376:       }
                   11377:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11378:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11379:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  11380:       }
                   11381:       fprintf(ficreseij,"******\n");
1.235     brouard  11382:       printf("******\n");
1.219     brouard  11383:       
                   11384:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11385:       oldm=oldms;savm=savms;
1.235     brouard  11386:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  11387:       
1.219     brouard  11388:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  11389:     }
                   11390:     fclose(ficreseij);
1.208     brouard  11391:     printf("done evsij\n");fflush(stdout);
                   11392:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.218     brouard  11393:                
1.227     brouard  11394:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  11395:                
                   11396:                
1.201     brouard  11397:     strcpy(filerest,"T_");
                   11398:     strcat(filerest,fileresu);
1.127     brouard  11399:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   11400:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   11401:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   11402:     }
1.208     brouard  11403:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   11404:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.218     brouard  11405:                
1.126     brouard  11406: 
1.201     brouard  11407:     strcpy(fileresstde,"STDE_");
                   11408:     strcat(fileresstde,fileresu);
1.126     brouard  11409:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  11410:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   11411:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  11412:     }
1.227     brouard  11413:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   11414:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  11415: 
1.201     brouard  11416:     strcpy(filerescve,"CVE_");
                   11417:     strcat(filerescve,fileresu);
1.126     brouard  11418:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  11419:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   11420:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  11421:     }
1.227     brouard  11422:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   11423:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  11424: 
1.201     brouard  11425:     strcpy(fileresv,"V_");
                   11426:     strcat(fileresv,fileresu);
1.126     brouard  11427:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   11428:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11429:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11430:     }
1.227     brouard  11431:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   11432:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  11433: 
1.145     brouard  11434:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11435:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   11436:           
1.235     brouard  11437:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11438:     if (cptcovn < 1){i1=1;}
                   11439:     
                   11440:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11441:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253   ! brouard  11442:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11443:        continue;
1.242     brouard  11444:       printf("\n#****** Result for:");
                   11445:       fprintf(ficrest,"\n#****** Result for:");
                   11446:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  11447:       for(j=1;j<=cptcoveff;j++){ 
                   11448:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11449:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11450:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11451:       }
1.235     brouard  11452:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11453:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11454:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11455:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11456:       }        
1.208     brouard  11457:       fprintf(ficrest,"******\n");
1.227     brouard  11458:       fprintf(ficlog,"******\n");
                   11459:       printf("******\n");
1.208     brouard  11460:       
                   11461:       fprintf(ficresstdeij,"\n#****** ");
                   11462:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  11463:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11464:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11465:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  11466:       }
1.235     brouard  11467:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11468:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11469:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11470:       }        
1.208     brouard  11471:       fprintf(ficresstdeij,"******\n");
                   11472:       fprintf(ficrescveij,"******\n");
                   11473:       
                   11474:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  11475:       /* pstamp(ficresvij); */
1.225     brouard  11476:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  11477:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11478:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11479:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11480:       }        
1.208     brouard  11481:       fprintf(ficresvij,"******\n");
                   11482:       
                   11483:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11484:       oldm=oldms;savm=savms;
1.235     brouard  11485:       printf(" cvevsij ");
                   11486:       fprintf(ficlog, " cvevsij ");
                   11487:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  11488:       printf(" end cvevsij \n ");
                   11489:       fprintf(ficlog, " end cvevsij \n ");
                   11490:       
                   11491:       /*
                   11492:        */
                   11493:       /* goto endfree; */
                   11494:       
                   11495:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11496:       pstamp(ficrest);
                   11497:       
                   11498:       
                   11499:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  11500:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   11501:        cptcod= 0; /* To be deleted */
                   11502:        printf("varevsij vpopbased=%d \n",vpopbased);
                   11503:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  11504:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  11505:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   11506:        if(vpopbased==1)
                   11507:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   11508:        else
                   11509:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   11510:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   11511:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   11512:        fprintf(ficrest,"\n");
                   11513:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   11514:        epj=vector(1,nlstate+1);
                   11515:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   11516:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   11517:        for(age=bage; age <=fage ;age++){
1.235     brouard  11518:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  11519:          if (vpopbased==1) {
                   11520:            if(mobilav ==0){
                   11521:              for(i=1; i<=nlstate;i++)
                   11522:                prlim[i][i]=probs[(int)age][i][k];
                   11523:            }else{ /* mobilav */ 
                   11524:              for(i=1; i<=nlstate;i++)
                   11525:                prlim[i][i]=mobaverage[(int)age][i][k];
                   11526:            }
                   11527:          }
1.219     brouard  11528:          
1.227     brouard  11529:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   11530:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   11531:          /* printf(" age %4.0f ",age); */
                   11532:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   11533:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   11534:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   11535:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   11536:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   11537:            }
                   11538:            epj[nlstate+1] +=epj[j];
                   11539:          }
                   11540:          /* printf(" age %4.0f \n",age); */
1.219     brouard  11541:          
1.227     brouard  11542:          for(i=1, vepp=0.;i <=nlstate;i++)
                   11543:            for(j=1;j <=nlstate;j++)
                   11544:              vepp += vareij[i][j][(int)age];
                   11545:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   11546:          for(j=1;j <=nlstate;j++){
                   11547:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   11548:          }
                   11549:          fprintf(ficrest,"\n");
                   11550:        }
1.208     brouard  11551:       } /* End vpopbased */
                   11552:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11553:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11554:       free_vector(epj,1,nlstate+1);
1.235     brouard  11555:       printf("done selection\n");fflush(stdout);
                   11556:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  11557:       
1.145     brouard  11558:       /*}*/
1.235     brouard  11559:     } /* End k selection */
1.227     brouard  11560: 
                   11561:     printf("done State-specific expectancies\n");fflush(stdout);
                   11562:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   11563: 
1.126     brouard  11564:     /*------- Variance of period (stable) prevalence------*/   
1.227     brouard  11565:     
1.201     brouard  11566:     strcpy(fileresvpl,"VPL_");
                   11567:     strcat(fileresvpl,fileresu);
1.126     brouard  11568:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   11569:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   11570:       exit(0);
                   11571:     }
1.208     brouard  11572:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   11573:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.227     brouard  11574:     
1.145     brouard  11575:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11576:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
1.227     brouard  11577:     
1.235     brouard  11578:     i1=pow(2,cptcoveff);
                   11579:     if (cptcovn < 1){i1=1;}
                   11580: 
                   11581:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11582:     for(k=1; k<=i1;k++){
1.253   ! brouard  11583:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11584:        continue;
1.227     brouard  11585:       fprintf(ficresvpl,"\n#****** ");
                   11586:       printf("\n#****** ");
                   11587:       fprintf(ficlog,"\n#****** ");
                   11588:       for(j=1;j<=cptcoveff;j++) {
                   11589:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11590:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11591:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11592:       }
1.235     brouard  11593:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11594:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11595:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11596:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11597:       }        
1.227     brouard  11598:       fprintf(ficresvpl,"******\n");
                   11599:       printf("******\n");
                   11600:       fprintf(ficlog,"******\n");
                   11601:       
                   11602:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   11603:       oldm=oldms;savm=savms;
1.235     brouard  11604:       varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, strstart, nres);
1.227     brouard  11605:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
1.145     brouard  11606:       /*}*/
1.126     brouard  11607:     }
1.227     brouard  11608:     
1.126     brouard  11609:     fclose(ficresvpl);
1.208     brouard  11610:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   11611:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
1.227     brouard  11612:     
                   11613:     free_vector(weight,1,n);
                   11614:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   11615:     free_imatrix(s,1,maxwav+1,1,n);
                   11616:     free_matrix(anint,1,maxwav,1,n); 
                   11617:     free_matrix(mint,1,maxwav,1,n);
                   11618:     free_ivector(cod,1,n);
                   11619:     free_ivector(tab,1,NCOVMAX);
                   11620:     fclose(ficresstdeij);
                   11621:     fclose(ficrescveij);
                   11622:     fclose(ficresvij);
                   11623:     fclose(ficrest);
                   11624:     fclose(ficpar);
                   11625:     
                   11626:     
1.126     brouard  11627:     /*---------- End : free ----------------*/
1.219     brouard  11628:     if (mobilav!=0 ||mobilavproj !=0)
                   11629:       free_ma3x(mobaverages,1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
1.218     brouard  11630:     free_ma3x(probs,1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  11631:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11632:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  11633:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  11634:   /* endfree:*/
                   11635:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11636:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11637:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11638:   free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
1.233     brouard  11639:   free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
1.227     brouard  11640:   free_matrix(coqvar,1,maxwav,1,n);
                   11641:   free_matrix(covar,0,NCOVMAX,1,n);
                   11642:   free_matrix(matcov,1,npar,1,npar);
                   11643:   free_matrix(hess,1,npar,1,npar);
                   11644:   /*free_vector(delti,1,npar);*/
                   11645:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11646:   free_matrix(agev,1,maxwav,1,imx);
                   11647:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   11648:   
                   11649:   free_ivector(ncodemax,1,NCOVMAX);
                   11650:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   11651:   free_ivector(Dummy,-1,NCOVMAX);
                   11652:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  11653:   free_ivector(DummyV,1,NCOVMAX);
                   11654:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  11655:   free_ivector(Typevar,-1,NCOVMAX);
                   11656:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  11657:   free_ivector(TvarsQ,1,NCOVMAX);
                   11658:   free_ivector(TvarsQind,1,NCOVMAX);
                   11659:   free_ivector(TvarsD,1,NCOVMAX);
                   11660:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  11661:   free_ivector(TvarFD,1,NCOVMAX);
                   11662:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  11663:   free_ivector(TvarF,1,NCOVMAX);
                   11664:   free_ivector(TvarFind,1,NCOVMAX);
                   11665:   free_ivector(TvarV,1,NCOVMAX);
                   11666:   free_ivector(TvarVind,1,NCOVMAX);
                   11667:   free_ivector(TvarA,1,NCOVMAX);
                   11668:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  11669:   free_ivector(TvarFQ,1,NCOVMAX);
                   11670:   free_ivector(TvarFQind,1,NCOVMAX);
                   11671:   free_ivector(TvarVD,1,NCOVMAX);
                   11672:   free_ivector(TvarVDind,1,NCOVMAX);
                   11673:   free_ivector(TvarVQ,1,NCOVMAX);
                   11674:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  11675:   free_ivector(Tvarsel,1,NCOVMAX);
                   11676:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  11677:   free_ivector(Tposprod,1,NCOVMAX);
                   11678:   free_ivector(Tprod,1,NCOVMAX);
                   11679:   free_ivector(Tvaraff,1,NCOVMAX);
                   11680:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   11681:   free_ivector(Tage,1,NCOVMAX);
                   11682:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  11683:   free_ivector(TmodelInvind,1,NCOVMAX);
                   11684:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  11685:   
                   11686:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   11687:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  11688:   fflush(fichtm);
                   11689:   fflush(ficgp);
                   11690:   
1.227     brouard  11691:   
1.126     brouard  11692:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  11693:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   11694:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  11695:   }else{
                   11696:     printf("End of Imach\n");
                   11697:     fprintf(ficlog,"End of Imach\n");
                   11698:   }
                   11699:   printf("See log file on %s\n",filelog);
                   11700:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  11701:   /*(void) gettimeofday(&end_time,&tzp);*/
                   11702:   rend_time = time(NULL);  
                   11703:   end_time = *localtime(&rend_time);
                   11704:   /* tml = *localtime(&end_time.tm_sec); */
                   11705:   strcpy(strtend,asctime(&end_time));
1.126     brouard  11706:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   11707:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  11708:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  11709:   
1.157     brouard  11710:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   11711:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   11712:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  11713:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   11714: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   11715:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11716:   fclose(fichtm);
                   11717:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11718:   fclose(fichtmcov);
                   11719:   fclose(ficgp);
                   11720:   fclose(ficlog);
                   11721:   /*------ End -----------*/
1.227     brouard  11722:   
                   11723:   
                   11724:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  11725: #ifdef WIN32
1.227     brouard  11726:   if (_chdir(pathcd) != 0)
                   11727:     printf("Can't move to directory %s!\n",path);
                   11728:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  11729: #else
1.227     brouard  11730:     if(chdir(pathcd) != 0)
                   11731:       printf("Can't move to directory %s!\n", path);
                   11732:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  11733: #endif 
1.126     brouard  11734:     printf("Current directory %s!\n",pathcd);
                   11735:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   11736:   sprintf(plotcmd,"gnuplot");
1.157     brouard  11737: #ifdef _WIN32
1.126     brouard  11738:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   11739: #endif
                   11740:   if(!stat(plotcmd,&info)){
1.158     brouard  11741:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11742:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  11743:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  11744:     }else
                   11745:       strcpy(pplotcmd,plotcmd);
1.157     brouard  11746: #ifdef __unix
1.126     brouard  11747:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   11748:     if(!stat(plotcmd,&info)){
1.158     brouard  11749:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11750:     }else
                   11751:       strcpy(pplotcmd,plotcmd);
                   11752: #endif
                   11753:   }else
                   11754:     strcpy(pplotcmd,plotcmd);
                   11755:   
                   11756:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  11757:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  11758:   
1.126     brouard  11759:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  11760:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  11761:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  11762:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  11763:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  11764:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  11765:   }
1.158     brouard  11766:   printf(" Successful, please wait...");
1.126     brouard  11767:   while (z[0] != 'q') {
                   11768:     /* chdir(path); */
1.154     brouard  11769:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  11770:     scanf("%s",z);
                   11771: /*     if (z[0] == 'c') system("./imach"); */
                   11772:     if (z[0] == 'e') {
1.158     brouard  11773: #ifdef __APPLE__
1.152     brouard  11774:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  11775: #elif __linux
                   11776:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  11777: #else
1.152     brouard  11778:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  11779: #endif
                   11780:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   11781:       system(pplotcmd);
1.126     brouard  11782:     }
                   11783:     else if (z[0] == 'g') system(plotcmd);
                   11784:     else if (z[0] == 'q') exit(0);
                   11785:   }
1.227     brouard  11786: end:
1.126     brouard  11787:   while (z[0] != 'q') {
1.195     brouard  11788:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  11789:     scanf("%s",z);
                   11790:   }
                   11791: }

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