Annotation of imach/src/imach.c, revision 1.254

1.254   ! brouard     1: /* $Id: imach.c,v 1.253 2016/12/15 11:59:41 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.254   ! brouard     4:   Revision 1.253  2016/12/15 11:59:41  brouard
        !             5:   Summary: 0.99 in progress
        !             6: 
1.253     brouard     7:   Revision 1.252  2016/09/15 21:15:37  brouard
                      8:   *** empty log message ***
                      9: 
1.252     brouard    10:   Revision 1.251  2016/09/15 15:01:13  brouard
                     11:   Summary: not working
                     12: 
1.251     brouard    13:   Revision 1.250  2016/09/08 16:07:27  brouard
                     14:   Summary: continue
                     15: 
1.250     brouard    16:   Revision 1.249  2016/09/07 17:14:18  brouard
                     17:   Summary: Starting values from frequencies
                     18: 
1.249     brouard    19:   Revision 1.248  2016/09/07 14:10:18  brouard
                     20:   *** empty log message ***
                     21: 
1.248     brouard    22:   Revision 1.247  2016/09/02 11:11:21  brouard
                     23:   *** empty log message ***
                     24: 
1.247     brouard    25:   Revision 1.246  2016/09/02 08:49:22  brouard
                     26:   *** empty log message ***
                     27: 
1.246     brouard    28:   Revision 1.245  2016/09/02 07:25:01  brouard
                     29:   *** empty log message ***
                     30: 
1.245     brouard    31:   Revision 1.244  2016/09/02 07:17:34  brouard
                     32:   *** empty log message ***
                     33: 
1.244     brouard    34:   Revision 1.243  2016/09/02 06:45:35  brouard
                     35:   *** empty log message ***
                     36: 
1.243     brouard    37:   Revision 1.242  2016/08/30 15:01:20  brouard
                     38:   Summary: Fixing a lots
                     39: 
1.242     brouard    40:   Revision 1.241  2016/08/29 17:17:25  brouard
                     41:   Summary: gnuplot problem in Back projection to fix
                     42: 
1.241     brouard    43:   Revision 1.240  2016/08/29 07:53:18  brouard
                     44:   Summary: Better
                     45: 
1.240     brouard    46:   Revision 1.239  2016/08/26 15:51:03  brouard
                     47:   Summary: Improvement in Powell output in order to copy and paste
                     48: 
                     49:   Author:
                     50: 
1.239     brouard    51:   Revision 1.238  2016/08/26 14:23:35  brouard
                     52:   Summary: Starting tests of 0.99
                     53: 
1.238     brouard    54:   Revision 1.237  2016/08/26 09:20:19  brouard
                     55:   Summary: to valgrind
                     56: 
1.237     brouard    57:   Revision 1.236  2016/08/25 10:50:18  brouard
                     58:   *** empty log message ***
                     59: 
1.236     brouard    60:   Revision 1.235  2016/08/25 06:59:23  brouard
                     61:   *** empty log message ***
                     62: 
1.235     brouard    63:   Revision 1.234  2016/08/23 16:51:20  brouard
                     64:   *** empty log message ***
                     65: 
1.234     brouard    66:   Revision 1.233  2016/08/23 07:40:50  brouard
                     67:   Summary: not working
                     68: 
1.233     brouard    69:   Revision 1.232  2016/08/22 14:20:21  brouard
                     70:   Summary: not working
                     71: 
1.232     brouard    72:   Revision 1.231  2016/08/22 07:17:15  brouard
                     73:   Summary: not working
                     74: 
1.231     brouard    75:   Revision 1.230  2016/08/22 06:55:53  brouard
                     76:   Summary: Not working
                     77: 
1.230     brouard    78:   Revision 1.229  2016/07/23 09:45:53  brouard
                     79:   Summary: Completing for func too
                     80: 
1.229     brouard    81:   Revision 1.228  2016/07/22 17:45:30  brouard
                     82:   Summary: Fixing some arrays, still debugging
                     83: 
1.227     brouard    84:   Revision 1.226  2016/07/12 18:42:34  brouard
                     85:   Summary: temp
                     86: 
1.226     brouard    87:   Revision 1.225  2016/07/12 08:40:03  brouard
                     88:   Summary: saving but not running
                     89: 
1.225     brouard    90:   Revision 1.224  2016/07/01 13:16:01  brouard
                     91:   Summary: Fixes
                     92: 
1.224     brouard    93:   Revision 1.223  2016/02/19 09:23:35  brouard
                     94:   Summary: temporary
                     95: 
1.223     brouard    96:   Revision 1.222  2016/02/17 08:14:50  brouard
                     97:   Summary: Probably last 0.98 stable version 0.98r6
                     98: 
1.222     brouard    99:   Revision 1.221  2016/02/15 23:35:36  brouard
                    100:   Summary: minor bug
                    101: 
1.220     brouard   102:   Revision 1.219  2016/02/15 00:48:12  brouard
                    103:   *** empty log message ***
                    104: 
1.219     brouard   105:   Revision 1.218  2016/02/12 11:29:23  brouard
                    106:   Summary: 0.99 Back projections
                    107: 
1.218     brouard   108:   Revision 1.217  2015/12/23 17:18:31  brouard
                    109:   Summary: Experimental backcast
                    110: 
1.217     brouard   111:   Revision 1.216  2015/12/18 17:32:11  brouard
                    112:   Summary: 0.98r4 Warning and status=-2
                    113: 
                    114:   Version 0.98r4 is now:
                    115:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    116:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    117:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    118: 
1.216     brouard   119:   Revision 1.215  2015/12/16 08:52:24  brouard
                    120:   Summary: 0.98r4 working
                    121: 
1.215     brouard   122:   Revision 1.214  2015/12/16 06:57:54  brouard
                    123:   Summary: temporary not working
                    124: 
1.214     brouard   125:   Revision 1.213  2015/12/11 18:22:17  brouard
                    126:   Summary: 0.98r4
                    127: 
1.213     brouard   128:   Revision 1.212  2015/11/21 12:47:24  brouard
                    129:   Summary: minor typo
                    130: 
1.212     brouard   131:   Revision 1.211  2015/11/21 12:41:11  brouard
                    132:   Summary: 0.98r3 with some graph of projected cross-sectional
                    133: 
                    134:   Author: Nicolas Brouard
                    135: 
1.211     brouard   136:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   137:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   138:   Summary: Adding ftolpl parameter
                    139:   Author: N Brouard
                    140: 
                    141:   We had difficulties to get smoothed confidence intervals. It was due
                    142:   to the period prevalence which wasn't computed accurately. The inner
                    143:   parameter ftolpl is now an outer parameter of the .imach parameter
                    144:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    145:   computation are long.
                    146: 
1.209     brouard   147:   Revision 1.208  2015/11/17 14:31:57  brouard
                    148:   Summary: temporary
                    149: 
1.208     brouard   150:   Revision 1.207  2015/10/27 17:36:57  brouard
                    151:   *** empty log message ***
                    152: 
1.207     brouard   153:   Revision 1.206  2015/10/24 07:14:11  brouard
                    154:   *** empty log message ***
                    155: 
1.206     brouard   156:   Revision 1.205  2015/10/23 15:50:53  brouard
                    157:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    158: 
1.205     brouard   159:   Revision 1.204  2015/10/01 16:20:26  brouard
                    160:   Summary: Some new graphs of contribution to likelihood
                    161: 
1.204     brouard   162:   Revision 1.203  2015/09/30 17:45:14  brouard
                    163:   Summary: looking at better estimation of the hessian
                    164: 
                    165:   Also a better criteria for convergence to the period prevalence And
                    166:   therefore adding the number of years needed to converge. (The
                    167:   prevalence in any alive state shold sum to one
                    168: 
1.203     brouard   169:   Revision 1.202  2015/09/22 19:45:16  brouard
                    170:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    171: 
1.202     brouard   172:   Revision 1.201  2015/09/15 17:34:58  brouard
                    173:   Summary: 0.98r0
                    174: 
                    175:   - Some new graphs like suvival functions
                    176:   - Some bugs fixed like model=1+age+V2.
                    177: 
1.201     brouard   178:   Revision 1.200  2015/09/09 16:53:55  brouard
                    179:   Summary: Big bug thanks to Flavia
                    180: 
                    181:   Even model=1+age+V2. did not work anymore
                    182: 
1.200     brouard   183:   Revision 1.199  2015/09/07 14:09:23  brouard
                    184:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    185: 
1.199     brouard   186:   Revision 1.198  2015/09/03 07:14:39  brouard
                    187:   Summary: 0.98q5 Flavia
                    188: 
1.198     brouard   189:   Revision 1.197  2015/09/01 18:24:39  brouard
                    190:   *** empty log message ***
                    191: 
1.197     brouard   192:   Revision 1.196  2015/08/18 23:17:52  brouard
                    193:   Summary: 0.98q5
                    194: 
1.196     brouard   195:   Revision 1.195  2015/08/18 16:28:39  brouard
                    196:   Summary: Adding a hack for testing purpose
                    197: 
                    198:   After reading the title, ftol and model lines, if the comment line has
                    199:   a q, starting with #q, the answer at the end of the run is quit. It
                    200:   permits to run test files in batch with ctest. The former workaround was
                    201:   $ echo q | imach foo.imach
                    202: 
1.195     brouard   203:   Revision 1.194  2015/08/18 13:32:00  brouard
                    204:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    205: 
1.194     brouard   206:   Revision 1.193  2015/08/04 07:17:42  brouard
                    207:   Summary: 0.98q4
                    208: 
1.193     brouard   209:   Revision 1.192  2015/07/16 16:49:02  brouard
                    210:   Summary: Fixing some outputs
                    211: 
1.192     brouard   212:   Revision 1.191  2015/07/14 10:00:33  brouard
                    213:   Summary: Some fixes
                    214: 
1.191     brouard   215:   Revision 1.190  2015/05/05 08:51:13  brouard
                    216:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    217: 
                    218:   Fix 1+age+.
                    219: 
1.190     brouard   220:   Revision 1.189  2015/04/30 14:45:16  brouard
                    221:   Summary: 0.98q2
                    222: 
1.189     brouard   223:   Revision 1.188  2015/04/30 08:27:53  brouard
                    224:   *** empty log message ***
                    225: 
1.188     brouard   226:   Revision 1.187  2015/04/29 09:11:15  brouard
                    227:   *** empty log message ***
                    228: 
1.187     brouard   229:   Revision 1.186  2015/04/23 12:01:52  brouard
                    230:   Summary: V1*age is working now, version 0.98q1
                    231: 
                    232:   Some codes had been disabled in order to simplify and Vn*age was
                    233:   working in the optimization phase, ie, giving correct MLE parameters,
                    234:   but, as usual, outputs were not correct and program core dumped.
                    235: 
1.186     brouard   236:   Revision 1.185  2015/03/11 13:26:42  brouard
                    237:   Summary: Inclusion of compile and links command line for Intel Compiler
                    238: 
1.185     brouard   239:   Revision 1.184  2015/03/11 11:52:39  brouard
                    240:   Summary: Back from Windows 8. Intel Compiler
                    241: 
1.184     brouard   242:   Revision 1.183  2015/03/10 20:34:32  brouard
                    243:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    244: 
                    245:   We use directest instead of original Powell test; probably no
                    246:   incidence on the results, but better justifications;
                    247:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    248:   wrong results.
                    249: 
1.183     brouard   250:   Revision 1.182  2015/02/12 08:19:57  brouard
                    251:   Summary: Trying to keep directest which seems simpler and more general
                    252:   Author: Nicolas Brouard
                    253: 
1.182     brouard   254:   Revision 1.181  2015/02/11 23:22:24  brouard
                    255:   Summary: Comments on Powell added
                    256: 
                    257:   Author:
                    258: 
1.181     brouard   259:   Revision 1.180  2015/02/11 17:33:45  brouard
                    260:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    261: 
1.180     brouard   262:   Revision 1.179  2015/01/04 09:57:06  brouard
                    263:   Summary: back to OS/X
                    264: 
1.179     brouard   265:   Revision 1.178  2015/01/04 09:35:48  brouard
                    266:   *** empty log message ***
                    267: 
1.178     brouard   268:   Revision 1.177  2015/01/03 18:40:56  brouard
                    269:   Summary: Still testing ilc32 on OSX
                    270: 
1.177     brouard   271:   Revision 1.176  2015/01/03 16:45:04  brouard
                    272:   *** empty log message ***
                    273: 
1.176     brouard   274:   Revision 1.175  2015/01/03 16:33:42  brouard
                    275:   *** empty log message ***
                    276: 
1.175     brouard   277:   Revision 1.174  2015/01/03 16:15:49  brouard
                    278:   Summary: Still in cross-compilation
                    279: 
1.174     brouard   280:   Revision 1.173  2015/01/03 12:06:26  brouard
                    281:   Summary: trying to detect cross-compilation
                    282: 
1.173     brouard   283:   Revision 1.172  2014/12/27 12:07:47  brouard
                    284:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    285: 
1.172     brouard   286:   Revision 1.171  2014/12/23 13:26:59  brouard
                    287:   Summary: Back from Visual C
                    288: 
                    289:   Still problem with utsname.h on Windows
                    290: 
1.171     brouard   291:   Revision 1.170  2014/12/23 11:17:12  brouard
                    292:   Summary: Cleaning some \%% back to %%
                    293: 
                    294:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    295: 
1.170     brouard   296:   Revision 1.169  2014/12/22 23:08:31  brouard
                    297:   Summary: 0.98p
                    298: 
                    299:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    300: 
1.169     brouard   301:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   302:   Summary: update
1.169     brouard   303: 
1.168     brouard   304:   Revision 1.167  2014/12/22 13:50:56  brouard
                    305:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    306: 
                    307:   Testing on Linux 64
                    308: 
1.167     brouard   309:   Revision 1.166  2014/12/22 11:40:47  brouard
                    310:   *** empty log message ***
                    311: 
1.166     brouard   312:   Revision 1.165  2014/12/16 11:20:36  brouard
                    313:   Summary: After compiling on Visual C
                    314: 
                    315:   * imach.c (Module): Merging 1.61 to 1.162
                    316: 
1.165     brouard   317:   Revision 1.164  2014/12/16 10:52:11  brouard
                    318:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    319: 
                    320:   * imach.c (Module): Merging 1.61 to 1.162
                    321: 
1.164     brouard   322:   Revision 1.163  2014/12/16 10:30:11  brouard
                    323:   * imach.c (Module): Merging 1.61 to 1.162
                    324: 
1.163     brouard   325:   Revision 1.162  2014/09/25 11:43:39  brouard
                    326:   Summary: temporary backup 0.99!
                    327: 
1.162     brouard   328:   Revision 1.1  2014/09/16 11:06:58  brouard
                    329:   Summary: With some code (wrong) for nlopt
                    330: 
                    331:   Author:
                    332: 
                    333:   Revision 1.161  2014/09/15 20:41:41  brouard
                    334:   Summary: Problem with macro SQR on Intel compiler
                    335: 
1.161     brouard   336:   Revision 1.160  2014/09/02 09:24:05  brouard
                    337:   *** empty log message ***
                    338: 
1.160     brouard   339:   Revision 1.159  2014/09/01 10:34:10  brouard
                    340:   Summary: WIN32
                    341:   Author: Brouard
                    342: 
1.159     brouard   343:   Revision 1.158  2014/08/27 17:11:51  brouard
                    344:   *** empty log message ***
                    345: 
1.158     brouard   346:   Revision 1.157  2014/08/27 16:26:55  brouard
                    347:   Summary: Preparing windows Visual studio version
                    348:   Author: Brouard
                    349: 
                    350:   In order to compile on Visual studio, time.h is now correct and time_t
                    351:   and tm struct should be used. difftime should be used but sometimes I
                    352:   just make the differences in raw time format (time(&now).
                    353:   Trying to suppress #ifdef LINUX
                    354:   Add xdg-open for __linux in order to open default browser.
                    355: 
1.157     brouard   356:   Revision 1.156  2014/08/25 20:10:10  brouard
                    357:   *** empty log message ***
                    358: 
1.156     brouard   359:   Revision 1.155  2014/08/25 18:32:34  brouard
                    360:   Summary: New compile, minor changes
                    361:   Author: Brouard
                    362: 
1.155     brouard   363:   Revision 1.154  2014/06/20 17:32:08  brouard
                    364:   Summary: Outputs now all graphs of convergence to period prevalence
                    365: 
1.154     brouard   366:   Revision 1.153  2014/06/20 16:45:46  brouard
                    367:   Summary: If 3 live state, convergence to period prevalence on same graph
                    368:   Author: Brouard
                    369: 
1.153     brouard   370:   Revision 1.152  2014/06/18 17:54:09  brouard
                    371:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    372: 
1.152     brouard   373:   Revision 1.151  2014/06/18 16:43:30  brouard
                    374:   *** empty log message ***
                    375: 
1.151     brouard   376:   Revision 1.150  2014/06/18 16:42:35  brouard
                    377:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    378:   Author: brouard
                    379: 
1.150     brouard   380:   Revision 1.149  2014/06/18 15:51:14  brouard
                    381:   Summary: Some fixes in parameter files errors
                    382:   Author: Nicolas Brouard
                    383: 
1.149     brouard   384:   Revision 1.148  2014/06/17 17:38:48  brouard
                    385:   Summary: Nothing new
                    386:   Author: Brouard
                    387: 
                    388:   Just a new packaging for OS/X version 0.98nS
                    389: 
1.148     brouard   390:   Revision 1.147  2014/06/16 10:33:11  brouard
                    391:   *** empty log message ***
                    392: 
1.147     brouard   393:   Revision 1.146  2014/06/16 10:20:28  brouard
                    394:   Summary: Merge
                    395:   Author: Brouard
                    396: 
                    397:   Merge, before building revised version.
                    398: 
1.146     brouard   399:   Revision 1.145  2014/06/10 21:23:15  brouard
                    400:   Summary: Debugging with valgrind
                    401:   Author: Nicolas Brouard
                    402: 
                    403:   Lot of changes in order to output the results with some covariates
                    404:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    405:   improve the code.
                    406:   No more memory valgrind error but a lot has to be done in order to
                    407:   continue the work of splitting the code into subroutines.
                    408:   Also, decodemodel has been improved. Tricode is still not
                    409:   optimal. nbcode should be improved. Documentation has been added in
                    410:   the source code.
                    411: 
1.144     brouard   412:   Revision 1.143  2014/01/26 09:45:38  brouard
                    413:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    414: 
                    415:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    416:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    417: 
1.143     brouard   418:   Revision 1.142  2014/01/26 03:57:36  brouard
                    419:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    420: 
                    421:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    422: 
1.142     brouard   423:   Revision 1.141  2014/01/26 02:42:01  brouard
                    424:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    425: 
1.141     brouard   426:   Revision 1.140  2011/09/02 10:37:54  brouard
                    427:   Summary: times.h is ok with mingw32 now.
                    428: 
1.140     brouard   429:   Revision 1.139  2010/06/14 07:50:17  brouard
                    430:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    431:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    432: 
1.139     brouard   433:   Revision 1.138  2010/04/30 18:19:40  brouard
                    434:   *** empty log message ***
                    435: 
1.138     brouard   436:   Revision 1.137  2010/04/29 18:11:38  brouard
                    437:   (Module): Checking covariates for more complex models
                    438:   than V1+V2. A lot of change to be done. Unstable.
                    439: 
1.137     brouard   440:   Revision 1.136  2010/04/26 20:30:53  brouard
                    441:   (Module): merging some libgsl code. Fixing computation
                    442:   of likelione (using inter/intrapolation if mle = 0) in order to
                    443:   get same likelihood as if mle=1.
                    444:   Some cleaning of code and comments added.
                    445: 
1.136     brouard   446:   Revision 1.135  2009/10/29 15:33:14  brouard
                    447:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    448: 
1.135     brouard   449:   Revision 1.134  2009/10/29 13:18:53  brouard
                    450:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    451: 
1.134     brouard   452:   Revision 1.133  2009/07/06 10:21:25  brouard
                    453:   just nforces
                    454: 
1.133     brouard   455:   Revision 1.132  2009/07/06 08:22:05  brouard
                    456:   Many tings
                    457: 
1.132     brouard   458:   Revision 1.131  2009/06/20 16:22:47  brouard
                    459:   Some dimensions resccaled
                    460: 
1.131     brouard   461:   Revision 1.130  2009/05/26 06:44:34  brouard
                    462:   (Module): Max Covariate is now set to 20 instead of 8. A
                    463:   lot of cleaning with variables initialized to 0. Trying to make
                    464:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    465: 
1.130     brouard   466:   Revision 1.129  2007/08/31 13:49:27  lievre
                    467:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    468: 
1.129     lievre    469:   Revision 1.128  2006/06/30 13:02:05  brouard
                    470:   (Module): Clarifications on computing e.j
                    471: 
1.128     brouard   472:   Revision 1.127  2006/04/28 18:11:50  brouard
                    473:   (Module): Yes the sum of survivors was wrong since
                    474:   imach-114 because nhstepm was no more computed in the age
                    475:   loop. Now we define nhstepma in the age loop.
                    476:   (Module): In order to speed up (in case of numerous covariates) we
                    477:   compute health expectancies (without variances) in a first step
                    478:   and then all the health expectancies with variances or standard
                    479:   deviation (needs data from the Hessian matrices) which slows the
                    480:   computation.
                    481:   In the future we should be able to stop the program is only health
                    482:   expectancies and graph are needed without standard deviations.
                    483: 
1.127     brouard   484:   Revision 1.126  2006/04/28 17:23:28  brouard
                    485:   (Module): Yes the sum of survivors was wrong since
                    486:   imach-114 because nhstepm was no more computed in the age
                    487:   loop. Now we define nhstepma in the age loop.
                    488:   Version 0.98h
                    489: 
1.126     brouard   490:   Revision 1.125  2006/04/04 15:20:31  lievre
                    491:   Errors in calculation of health expectancies. Age was not initialized.
                    492:   Forecasting file added.
                    493: 
                    494:   Revision 1.124  2006/03/22 17:13:53  lievre
                    495:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    496:   The log-likelihood is printed in the log file
                    497: 
                    498:   Revision 1.123  2006/03/20 10:52:43  brouard
                    499:   * imach.c (Module): <title> changed, corresponds to .htm file
                    500:   name. <head> headers where missing.
                    501: 
                    502:   * imach.c (Module): Weights can have a decimal point as for
                    503:   English (a comma might work with a correct LC_NUMERIC environment,
                    504:   otherwise the weight is truncated).
                    505:   Modification of warning when the covariates values are not 0 or
                    506:   1.
                    507:   Version 0.98g
                    508: 
                    509:   Revision 1.122  2006/03/20 09:45:41  brouard
                    510:   (Module): Weights can have a decimal point as for
                    511:   English (a comma might work with a correct LC_NUMERIC environment,
                    512:   otherwise the weight is truncated).
                    513:   Modification of warning when the covariates values are not 0 or
                    514:   1.
                    515:   Version 0.98g
                    516: 
                    517:   Revision 1.121  2006/03/16 17:45:01  lievre
                    518:   * imach.c (Module): Comments concerning covariates added
                    519: 
                    520:   * imach.c (Module): refinements in the computation of lli if
                    521:   status=-2 in order to have more reliable computation if stepm is
                    522:   not 1 month. Version 0.98f
                    523: 
                    524:   Revision 1.120  2006/03/16 15:10:38  lievre
                    525:   (Module): refinements in the computation of lli if
                    526:   status=-2 in order to have more reliable computation if stepm is
                    527:   not 1 month. Version 0.98f
                    528: 
                    529:   Revision 1.119  2006/03/15 17:42:26  brouard
                    530:   (Module): Bug if status = -2, the loglikelihood was
                    531:   computed as likelihood omitting the logarithm. Version O.98e
                    532: 
                    533:   Revision 1.118  2006/03/14 18:20:07  brouard
                    534:   (Module): varevsij Comments added explaining the second
                    535:   table of variances if popbased=1 .
                    536:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    537:   (Module): Function pstamp added
                    538:   (Module): Version 0.98d
                    539: 
                    540:   Revision 1.117  2006/03/14 17:16:22  brouard
                    541:   (Module): varevsij Comments added explaining the second
                    542:   table of variances if popbased=1 .
                    543:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    544:   (Module): Function pstamp added
                    545:   (Module): Version 0.98d
                    546: 
                    547:   Revision 1.116  2006/03/06 10:29:27  brouard
                    548:   (Module): Variance-covariance wrong links and
                    549:   varian-covariance of ej. is needed (Saito).
                    550: 
                    551:   Revision 1.115  2006/02/27 12:17:45  brouard
                    552:   (Module): One freematrix added in mlikeli! 0.98c
                    553: 
                    554:   Revision 1.114  2006/02/26 12:57:58  brouard
                    555:   (Module): Some improvements in processing parameter
                    556:   filename with strsep.
                    557: 
                    558:   Revision 1.113  2006/02/24 14:20:24  brouard
                    559:   (Module): Memory leaks checks with valgrind and:
                    560:   datafile was not closed, some imatrix were not freed and on matrix
                    561:   allocation too.
                    562: 
                    563:   Revision 1.112  2006/01/30 09:55:26  brouard
                    564:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    565: 
                    566:   Revision 1.111  2006/01/25 20:38:18  brouard
                    567:   (Module): Lots of cleaning and bugs added (Gompertz)
                    568:   (Module): Comments can be added in data file. Missing date values
                    569:   can be a simple dot '.'.
                    570: 
                    571:   Revision 1.110  2006/01/25 00:51:50  brouard
                    572:   (Module): Lots of cleaning and bugs added (Gompertz)
                    573: 
                    574:   Revision 1.109  2006/01/24 19:37:15  brouard
                    575:   (Module): Comments (lines starting with a #) are allowed in data.
                    576: 
                    577:   Revision 1.108  2006/01/19 18:05:42  lievre
                    578:   Gnuplot problem appeared...
                    579:   To be fixed
                    580: 
                    581:   Revision 1.107  2006/01/19 16:20:37  brouard
                    582:   Test existence of gnuplot in imach path
                    583: 
                    584:   Revision 1.106  2006/01/19 13:24:36  brouard
                    585:   Some cleaning and links added in html output
                    586: 
                    587:   Revision 1.105  2006/01/05 20:23:19  lievre
                    588:   *** empty log message ***
                    589: 
                    590:   Revision 1.104  2005/09/30 16:11:43  lievre
                    591:   (Module): sump fixed, loop imx fixed, and simplifications.
                    592:   (Module): If the status is missing at the last wave but we know
                    593:   that the person is alive, then we can code his/her status as -2
                    594:   (instead of missing=-1 in earlier versions) and his/her
                    595:   contributions to the likelihood is 1 - Prob of dying from last
                    596:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    597:   the healthy state at last known wave). Version is 0.98
                    598: 
                    599:   Revision 1.103  2005/09/30 15:54:49  lievre
                    600:   (Module): sump fixed, loop imx fixed, and simplifications.
                    601: 
                    602:   Revision 1.102  2004/09/15 17:31:30  brouard
                    603:   Add the possibility to read data file including tab characters.
                    604: 
                    605:   Revision 1.101  2004/09/15 10:38:38  brouard
                    606:   Fix on curr_time
                    607: 
                    608:   Revision 1.100  2004/07/12 18:29:06  brouard
                    609:   Add version for Mac OS X. Just define UNIX in Makefile
                    610: 
                    611:   Revision 1.99  2004/06/05 08:57:40  brouard
                    612:   *** empty log message ***
                    613: 
                    614:   Revision 1.98  2004/05/16 15:05:56  brouard
                    615:   New version 0.97 . First attempt to estimate force of mortality
                    616:   directly from the data i.e. without the need of knowing the health
                    617:   state at each age, but using a Gompertz model: log u =a + b*age .
                    618:   This is the basic analysis of mortality and should be done before any
                    619:   other analysis, in order to test if the mortality estimated from the
                    620:   cross-longitudinal survey is different from the mortality estimated
                    621:   from other sources like vital statistic data.
                    622: 
                    623:   The same imach parameter file can be used but the option for mle should be -3.
                    624: 
1.133     brouard   625:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   626:   former routines in order to include the new code within the former code.
                    627: 
                    628:   The output is very simple: only an estimate of the intercept and of
                    629:   the slope with 95% confident intervals.
                    630: 
                    631:   Current limitations:
                    632:   A) Even if you enter covariates, i.e. with the
                    633:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    634:   B) There is no computation of Life Expectancy nor Life Table.
                    635: 
                    636:   Revision 1.97  2004/02/20 13:25:42  lievre
                    637:   Version 0.96d. Population forecasting command line is (temporarily)
                    638:   suppressed.
                    639: 
                    640:   Revision 1.96  2003/07/15 15:38:55  brouard
                    641:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    642:   rewritten within the same printf. Workaround: many printfs.
                    643: 
                    644:   Revision 1.95  2003/07/08 07:54:34  brouard
                    645:   * imach.c (Repository):
                    646:   (Repository): Using imachwizard code to output a more meaningful covariance
                    647:   matrix (cov(a12,c31) instead of numbers.
                    648: 
                    649:   Revision 1.94  2003/06/27 13:00:02  brouard
                    650:   Just cleaning
                    651: 
                    652:   Revision 1.93  2003/06/25 16:33:55  brouard
                    653:   (Module): On windows (cygwin) function asctime_r doesn't
                    654:   exist so I changed back to asctime which exists.
                    655:   (Module): Version 0.96b
                    656: 
                    657:   Revision 1.92  2003/06/25 16:30:45  brouard
                    658:   (Module): On windows (cygwin) function asctime_r doesn't
                    659:   exist so I changed back to asctime which exists.
                    660: 
                    661:   Revision 1.91  2003/06/25 15:30:29  brouard
                    662:   * imach.c (Repository): Duplicated warning errors corrected.
                    663:   (Repository): Elapsed time after each iteration is now output. It
                    664:   helps to forecast when convergence will be reached. Elapsed time
                    665:   is stamped in powell.  We created a new html file for the graphs
                    666:   concerning matrix of covariance. It has extension -cov.htm.
                    667: 
                    668:   Revision 1.90  2003/06/24 12:34:15  brouard
                    669:   (Module): Some bugs corrected for windows. Also, when
                    670:   mle=-1 a template is output in file "or"mypar.txt with the design
                    671:   of the covariance matrix to be input.
                    672: 
                    673:   Revision 1.89  2003/06/24 12:30:52  brouard
                    674:   (Module): Some bugs corrected for windows. Also, when
                    675:   mle=-1 a template is output in file "or"mypar.txt with the design
                    676:   of the covariance matrix to be input.
                    677: 
                    678:   Revision 1.88  2003/06/23 17:54:56  brouard
                    679:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    680: 
                    681:   Revision 1.87  2003/06/18 12:26:01  brouard
                    682:   Version 0.96
                    683: 
                    684:   Revision 1.86  2003/06/17 20:04:08  brouard
                    685:   (Module): Change position of html and gnuplot routines and added
                    686:   routine fileappend.
                    687: 
                    688:   Revision 1.85  2003/06/17 13:12:43  brouard
                    689:   * imach.c (Repository): Check when date of death was earlier that
                    690:   current date of interview. It may happen when the death was just
                    691:   prior to the death. In this case, dh was negative and likelihood
                    692:   was wrong (infinity). We still send an "Error" but patch by
                    693:   assuming that the date of death was just one stepm after the
                    694:   interview.
                    695:   (Repository): Because some people have very long ID (first column)
                    696:   we changed int to long in num[] and we added a new lvector for
                    697:   memory allocation. But we also truncated to 8 characters (left
                    698:   truncation)
                    699:   (Repository): No more line truncation errors.
                    700: 
                    701:   Revision 1.84  2003/06/13 21:44:43  brouard
                    702:   * imach.c (Repository): Replace "freqsummary" at a correct
                    703:   place. It differs from routine "prevalence" which may be called
                    704:   many times. Probs is memory consuming and must be used with
                    705:   parcimony.
                    706:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    707: 
                    708:   Revision 1.83  2003/06/10 13:39:11  lievre
                    709:   *** empty log message ***
                    710: 
                    711:   Revision 1.82  2003/06/05 15:57:20  brouard
                    712:   Add log in  imach.c and  fullversion number is now printed.
                    713: 
                    714: */
                    715: /*
                    716:    Interpolated Markov Chain
                    717: 
                    718:   Short summary of the programme:
                    719:   
1.227     brouard   720:   This program computes Healthy Life Expectancies or State-specific
                    721:   (if states aren't health statuses) Expectancies from
                    722:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    723: 
                    724:   -1- a first survey ("cross") where individuals from different ages
                    725:   are interviewed on their health status or degree of disability (in
                    726:   the case of a health survey which is our main interest)
                    727: 
                    728:   -2- at least a second wave of interviews ("longitudinal") which
                    729:   measure each change (if any) in individual health status.  Health
                    730:   expectancies are computed from the time spent in each health state
                    731:   according to a model. More health states you consider, more time is
                    732:   necessary to reach the Maximum Likelihood of the parameters involved
                    733:   in the model.  The simplest model is the multinomial logistic model
                    734:   where pij is the probability to be observed in state j at the second
                    735:   wave conditional to be observed in state i at the first
                    736:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    737:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    738:   have a more complex model than "constant and age", you should modify
                    739:   the program where the markup *Covariates have to be included here
                    740:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   741:   convergence.
                    742: 
                    743:   The advantage of this computer programme, compared to a simple
                    744:   multinomial logistic model, is clear when the delay between waves is not
                    745:   identical for each individual. Also, if a individual missed an
                    746:   intermediate interview, the information is lost, but taken into
                    747:   account using an interpolation or extrapolation.  
                    748: 
                    749:   hPijx is the probability to be observed in state i at age x+h
                    750:   conditional to the observed state i at age x. The delay 'h' can be
                    751:   split into an exact number (nh*stepm) of unobserved intermediate
                    752:   states. This elementary transition (by month, quarter,
                    753:   semester or year) is modelled as a multinomial logistic.  The hPx
                    754:   matrix is simply the matrix product of nh*stepm elementary matrices
                    755:   and the contribution of each individual to the likelihood is simply
                    756:   hPijx.
                    757: 
                    758:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   759:   of the life expectancies. It also computes the period (stable) prevalence.
                    760: 
                    761: Back prevalence and projections:
1.227     brouard   762: 
                    763:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    764:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    765:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    766:    mobilavproj)
                    767: 
                    768:     Computes the back prevalence limit for any combination of
                    769:     covariate values k at any age between ageminpar and agemaxpar and
                    770:     returns it in **bprlim. In the loops,
                    771: 
                    772:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    773:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    774: 
                    775:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   776:    Computes for any combination of covariates k and any age between bage and fage 
                    777:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    778:                        oldm=oldms;savm=savms;
1.227     brouard   779: 
                    780:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);
1.218     brouard   781:      Computes the transition matrix starting at age 'age' over
                    782:      'nhstepm*hstepm*stepm' months (i.e. until
                    783:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   784:      nhstepm*hstepm matrices. 
                    785: 
                    786:      Returns p3mat[i][j][h] after calling
                    787:      p3mat[i][j][h]=matprod2(newm,
                    788:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    789:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    790:      oldm);
1.226     brouard   791: 
                    792: Important routines
                    793: 
                    794: - func (or funcone), computes logit (pij) distinguishing
                    795:   o fixed variables (single or product dummies or quantitative);
                    796:   o varying variables by:
                    797:    (1) wave (single, product dummies, quantitative), 
                    798:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    799:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    800:        % varying dummy (not done) or quantitative (not done);
                    801: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    802:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    803: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    804:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    805:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   806: 
1.226     brouard   807: 
                    808:   
1.133     brouard   809:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    810:            Institut national d'études démographiques, Paris.
1.126     brouard   811:   This software have been partly granted by Euro-REVES, a concerted action
                    812:   from the European Union.
                    813:   It is copyrighted identically to a GNU software product, ie programme and
                    814:   software can be distributed freely for non commercial use. Latest version
                    815:   can be accessed at http://euroreves.ined.fr/imach .
                    816: 
                    817:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    818:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    819:   
                    820:   **********************************************************************/
                    821: /*
                    822:   main
                    823:   read parameterfile
                    824:   read datafile
                    825:   concatwav
                    826:   freqsummary
                    827:   if (mle >= 1)
                    828:     mlikeli
                    829:   print results files
                    830:   if mle==1 
                    831:      computes hessian
                    832:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    833:       begin-prev-date,...
                    834:   open gnuplot file
                    835:   open html file
1.145     brouard   836:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    837:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    838:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    839:     freexexit2 possible for memory heap.
                    840: 
                    841:   h Pij x                         | pij_nom  ficrestpij
                    842:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    843:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    844:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    845: 
                    846:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    847:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    848:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    849:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    850:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    851: 
1.126     brouard   852:   forecasting if prevfcast==1 prevforecast call prevalence()
                    853:   health expectancies
                    854:   Variance-covariance of DFLE
                    855:   prevalence()
                    856:    movingaverage()
                    857:   varevsij() 
                    858:   if popbased==1 varevsij(,popbased)
                    859:   total life expectancies
                    860:   Variance of period (stable) prevalence
                    861:  end
                    862: */
                    863: 
1.187     brouard   864: /* #define DEBUG */
                    865: /* #define DEBUGBRENT */
1.203     brouard   866: /* #define DEBUGLINMIN */
                    867: /* #define DEBUGHESS */
                    868: #define DEBUGHESSIJ
1.224     brouard   869: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   870: #define POWELL /* Instead of NLOPT */
1.224     brouard   871: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   872: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    873: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   874: 
                    875: #include <math.h>
                    876: #include <stdio.h>
                    877: #include <stdlib.h>
                    878: #include <string.h>
1.226     brouard   879: #include <ctype.h>
1.159     brouard   880: 
                    881: #ifdef _WIN32
                    882: #include <io.h>
1.172     brouard   883: #include <windows.h>
                    884: #include <tchar.h>
1.159     brouard   885: #else
1.126     brouard   886: #include <unistd.h>
1.159     brouard   887: #endif
1.126     brouard   888: 
                    889: #include <limits.h>
                    890: #include <sys/types.h>
1.171     brouard   891: 
                    892: #if defined(__GNUC__)
                    893: #include <sys/utsname.h> /* Doesn't work on Windows */
                    894: #endif
                    895: 
1.126     brouard   896: #include <sys/stat.h>
                    897: #include <errno.h>
1.159     brouard   898: /* extern int errno; */
1.126     brouard   899: 
1.157     brouard   900: /* #ifdef LINUX */
                    901: /* #include <time.h> */
                    902: /* #include "timeval.h" */
                    903: /* #else */
                    904: /* #include <sys/time.h> */
                    905: /* #endif */
                    906: 
1.126     brouard   907: #include <time.h>
                    908: 
1.136     brouard   909: #ifdef GSL
                    910: #include <gsl/gsl_errno.h>
                    911: #include <gsl/gsl_multimin.h>
                    912: #endif
                    913: 
1.167     brouard   914: 
1.162     brouard   915: #ifdef NLOPT
                    916: #include <nlopt.h>
                    917: typedef struct {
                    918:   double (* function)(double [] );
                    919: } myfunc_data ;
                    920: #endif
                    921: 
1.126     brouard   922: /* #include <libintl.h> */
                    923: /* #define _(String) gettext (String) */
                    924: 
1.251     brouard   925: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   926: 
                    927: #define GNUPLOTPROGRAM "gnuplot"
                    928: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    929: #define FILENAMELENGTH 132
                    930: 
                    931: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    932: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    933: 
1.144     brouard   934: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    935: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   936: 
                    937: #define NINTERVMAX 8
1.144     brouard   938: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    939: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    940: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   941: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   942: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    943: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   944: #define MAXN 20000
1.144     brouard   945: #define YEARM 12. /**< Number of months per year */
1.218     brouard   946: /* #define AGESUP 130 */
                    947: #define AGESUP 150
                    948: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard   949: #define AGEBASE 40
1.194     brouard   950: #define AGEOVERFLOW 1.e20
1.164     brouard   951: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard   952: #ifdef _WIN32
                    953: #define DIRSEPARATOR '\\'
                    954: #define CHARSEPARATOR "\\"
                    955: #define ODIRSEPARATOR '/'
                    956: #else
1.126     brouard   957: #define DIRSEPARATOR '/'
                    958: #define CHARSEPARATOR "/"
                    959: #define ODIRSEPARATOR '\\'
                    960: #endif
                    961: 
1.254   ! brouard   962: /* $Id: imach.c,v 1.253 2016/12/15 11:59:41 brouard Exp $ */
1.126     brouard   963: /* $State: Exp $ */
1.196     brouard   964: #include "version.h"
                    965: char version[]=__IMACH_VERSION__;
1.224     brouard   966: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.254   ! brouard   967: char fullversion[]="$Revision: 1.253 $ $Date: 2016/12/15 11:59:41 $"; 
1.126     brouard   968: char strstart[80];
                    969: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard   970: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard   971: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard   972: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                    973: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                    974: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard   975: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                    976: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard   977: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                    978: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                    979: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard   980: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                    981: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard   982: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard   983: int nsd=0; /**< Total number of single dummy variables (output) */
                    984: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard   985: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard   986: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard   987: int ntveff=0; /**< ntveff number of effective time varying variables */
                    988: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard   989: int cptcov=0; /* Working variable */
1.218     brouard   990: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard   991: int npar=NPARMAX;
                    992: int nlstate=2; /* Number of live states */
                    993: int ndeath=1; /* Number of dead states */
1.130     brouard   994: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard   995: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard   996: int popbased=0;
                    997: 
                    998: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard   999: int maxwav=0; /* Maxim number of waves */
                   1000: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1001: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1002: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1003:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1004: int mle=1, weightopt=0;
1.126     brouard  1005: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1006: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1007: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1008:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1009: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1010: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1011: 
1.130     brouard  1012: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1013: double **matprod2(); /* test */
1.126     brouard  1014: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1015: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1016: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1017: 
1.136     brouard  1018: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1019: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1020: FILE *ficlog, *ficrespow;
1.130     brouard  1021: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1022: double fretone; /* Only one call to likelihood */
1.130     brouard  1023: long ipmx=0; /* Number of contributions */
1.126     brouard  1024: double sw; /* Sum of weights */
                   1025: char filerespow[FILENAMELENGTH];
                   1026: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1027: FILE *ficresilk;
                   1028: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1029: FILE *ficresprobmorprev;
                   1030: FILE *fichtm, *fichtmcov; /* Html File */
                   1031: FILE *ficreseij;
                   1032: char filerese[FILENAMELENGTH];
                   1033: FILE *ficresstdeij;
                   1034: char fileresstde[FILENAMELENGTH];
                   1035: FILE *ficrescveij;
                   1036: char filerescve[FILENAMELENGTH];
                   1037: FILE  *ficresvij;
                   1038: char fileresv[FILENAMELENGTH];
                   1039: FILE  *ficresvpl;
                   1040: char fileresvpl[FILENAMELENGTH];
                   1041: char title[MAXLINE];
1.234     brouard  1042: char model[MAXLINE]; /**< The model line */
1.217     brouard  1043: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1044: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1045: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1046: char command[FILENAMELENGTH];
                   1047: int  outcmd=0;
                   1048: 
1.217     brouard  1049: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1050: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1051: char filelog[FILENAMELENGTH]; /* Log file */
                   1052: char filerest[FILENAMELENGTH];
                   1053: char fileregp[FILENAMELENGTH];
                   1054: char popfile[FILENAMELENGTH];
                   1055: 
                   1056: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1057: 
1.157     brouard  1058: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1059: /* struct timezone tzp; */
                   1060: /* extern int gettimeofday(); */
                   1061: struct tm tml, *gmtime(), *localtime();
                   1062: 
                   1063: extern time_t time();
                   1064: 
                   1065: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1066: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1067: struct tm tm;
                   1068: 
1.126     brouard  1069: char strcurr[80], strfor[80];
                   1070: 
                   1071: char *endptr;
                   1072: long lval;
                   1073: double dval;
                   1074: 
                   1075: #define NR_END 1
                   1076: #define FREE_ARG char*
                   1077: #define FTOL 1.0e-10
                   1078: 
                   1079: #define NRANSI 
1.240     brouard  1080: #define ITMAX 200
                   1081: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1082: 
                   1083: #define TOL 2.0e-4 
                   1084: 
                   1085: #define CGOLD 0.3819660 
                   1086: #define ZEPS 1.0e-10 
                   1087: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1088: 
                   1089: #define GOLD 1.618034 
                   1090: #define GLIMIT 100.0 
                   1091: #define TINY 1.0e-20 
                   1092: 
                   1093: static double maxarg1,maxarg2;
                   1094: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1095: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1096:   
                   1097: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1098: #define rint(a) floor(a+0.5)
1.166     brouard  1099: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1100: #define mytinydouble 1.0e-16
1.166     brouard  1101: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1102: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1103: /* static double dsqrarg; */
                   1104: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1105: static double sqrarg;
                   1106: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1107: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1108: int agegomp= AGEGOMP;
                   1109: 
                   1110: int imx; 
                   1111: int stepm=1;
                   1112: /* Stepm, step in month: minimum step interpolation*/
                   1113: 
                   1114: int estepm;
                   1115: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1116: 
                   1117: int m,nb;
                   1118: long *num;
1.197     brouard  1119: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1120: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1121:                   covariate for which somebody answered excluding 
                   1122:                   undefined. Usually 2: 0 and 1. */
                   1123: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1124:                             covariate for which somebody answered including 
                   1125:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1126: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1127: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1128: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1129: double *ageexmed,*agecens;
                   1130: double dateintmean=0;
                   1131: 
                   1132: double *weight;
                   1133: int **s; /* Status */
1.141     brouard  1134: double *agedc;
1.145     brouard  1135: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1136:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1137:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.225     brouard  1138: double **coqvar; /* Fixed quantitative covariate iqv */
                   1139: double ***cotvar; /* Time varying covariate itv */
                   1140: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1141: double  idx; 
                   1142: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1143: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1144: /*k          1  2   3   4     5    6    7     8    9 */
                   1145: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1146: /* Tndvar[k]    1   2   3               4          5 */
                   1147: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1148: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1149: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1150: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1151: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1152: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1153: /* Tprod[i]=k           4               7            */
                   1154: /* Tage[i]=k                  5               8      */
                   1155: /* */
                   1156: /* Type                    */
                   1157: /* V         1  2  3  4  5 */
                   1158: /*           F  F  V  V  V */
                   1159: /*           D  Q  D  D  Q */
                   1160: /*                         */
                   1161: int *TvarsD;
                   1162: int *TvarsDind;
                   1163: int *TvarsQ;
                   1164: int *TvarsQind;
                   1165: 
1.235     brouard  1166: #define MAXRESULTLINES 10
                   1167: int nresult=0;
                   1168: int TKresult[MAXRESULTLINES];
1.237     brouard  1169: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1170: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1171: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1172: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1173: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1174: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1175: 
1.234     brouard  1176: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1177: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1178: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1179: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1180: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1181: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1182: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1183: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1184: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1185: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1186: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1187: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1188: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1189: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1190: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1191: 
1.230     brouard  1192: int *Tvarsel; /**< Selected covariates for output */
                   1193: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1194: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1195: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1196: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1197: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1198: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1199: int *Tage;
1.227     brouard  1200: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1201: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1202: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1203: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1204: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1205: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1206: int **Tvard;
                   1207: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1208: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1209: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1210:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1211:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1212: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1213: double *lsurv, *lpop, *tpop;
                   1214: 
1.231     brouard  1215: #define FD 1; /* Fixed dummy covariate */
                   1216: #define FQ 2; /* Fixed quantitative covariate */
                   1217: #define FP 3; /* Fixed product covariate */
                   1218: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1219: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1220: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1221: #define VD 10; /* Varying dummy covariate */
                   1222: #define VQ 11; /* Varying quantitative covariate */
                   1223: #define VP 12; /* Varying product covariate */
                   1224: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1225: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1226: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1227: #define APFD 16; /* Age product * fixed dummy covariate */
                   1228: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1229: #define APVD 18; /* Age product * varying dummy covariate */
                   1230: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1231: 
                   1232: #define FTYPE 1; /* Fixed covariate */
                   1233: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1234: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1235: 
                   1236: struct kmodel{
                   1237:        int maintype; /* main type */
                   1238:        int subtype; /* subtype */
                   1239: };
                   1240: struct kmodel modell[NCOVMAX];
                   1241: 
1.143     brouard  1242: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1243: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1244: 
                   1245: /**************** split *************************/
                   1246: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1247: {
                   1248:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1249:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1250:   */ 
                   1251:   char *ss;                            /* pointer */
1.186     brouard  1252:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1253: 
                   1254:   l1 = strlen(path );                  /* length of path */
                   1255:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1256:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1257:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1258:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1259:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1260:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1261:     /* get current working directory */
                   1262:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1263: #ifdef WIN32
                   1264:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1265: #else
                   1266:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1267: #endif
1.126     brouard  1268:       return( GLOCK_ERROR_GETCWD );
                   1269:     }
                   1270:     /* got dirc from getcwd*/
                   1271:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1272:   } else {                             /* strip directory from path */
1.126     brouard  1273:     ss++;                              /* after this, the filename */
                   1274:     l2 = strlen( ss );                 /* length of filename */
                   1275:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1276:     strcpy( name, ss );                /* save file name */
                   1277:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1278:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1279:     printf(" DIRC2 = %s \n",dirc);
                   1280:   }
                   1281:   /* We add a separator at the end of dirc if not exists */
                   1282:   l1 = strlen( dirc );                 /* length of directory */
                   1283:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1284:     dirc[l1] =  DIRSEPARATOR;
                   1285:     dirc[l1+1] = 0; 
                   1286:     printf(" DIRC3 = %s \n",dirc);
                   1287:   }
                   1288:   ss = strrchr( name, '.' );           /* find last / */
                   1289:   if (ss >0){
                   1290:     ss++;
                   1291:     strcpy(ext,ss);                    /* save extension */
                   1292:     l1= strlen( name);
                   1293:     l2= strlen(ss)+1;
                   1294:     strncpy( finame, name, l1-l2);
                   1295:     finame[l1-l2]= 0;
                   1296:   }
                   1297: 
                   1298:   return( 0 );                         /* we're done */
                   1299: }
                   1300: 
                   1301: 
                   1302: /******************************************/
                   1303: 
                   1304: void replace_back_to_slash(char *s, char*t)
                   1305: {
                   1306:   int i;
                   1307:   int lg=0;
                   1308:   i=0;
                   1309:   lg=strlen(t);
                   1310:   for(i=0; i<= lg; i++) {
                   1311:     (s[i] = t[i]);
                   1312:     if (t[i]== '\\') s[i]='/';
                   1313:   }
                   1314: }
                   1315: 
1.132     brouard  1316: char *trimbb(char *out, char *in)
1.137     brouard  1317: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1318:   char *s;
                   1319:   s=out;
                   1320:   while (*in != '\0'){
1.137     brouard  1321:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1322:       in++;
                   1323:     }
                   1324:     *out++ = *in++;
                   1325:   }
                   1326:   *out='\0';
                   1327:   return s;
                   1328: }
                   1329: 
1.187     brouard  1330: /* char *substrchaine(char *out, char *in, char *chain) */
                   1331: /* { */
                   1332: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1333: /*   char *s, *t; */
                   1334: /*   t=in;s=out; */
                   1335: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1336: /*     *out++ = *in++; */
                   1337: /*   } */
                   1338: 
                   1339: /*   /\* *in matches *chain *\/ */
                   1340: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1341: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1342: /*   } */
                   1343: /*   in--; chain--; */
                   1344: /*   while ( (*in != '\0')){ */
                   1345: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1346: /*     *out++ = *in++; */
                   1347: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1348: /*   } */
                   1349: /*   *out='\0'; */
                   1350: /*   out=s; */
                   1351: /*   return out; */
                   1352: /* } */
                   1353: char *substrchaine(char *out, char *in, char *chain)
                   1354: {
                   1355:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1356:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1357: 
                   1358:   char *strloc;
                   1359: 
                   1360:   strcpy (out, in); 
                   1361:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1362:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1363:   if(strloc != NULL){ 
                   1364:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1365:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1366:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1367:   }
                   1368:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1369:   return out;
                   1370: }
                   1371: 
                   1372: 
1.145     brouard  1373: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1374: {
1.187     brouard  1375:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1376:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1377:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1378:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1379:   */
1.160     brouard  1380:   char *s, *t;
1.145     brouard  1381:   t=in;s=in;
                   1382:   while ((*in != occ) && (*in != '\0')){
                   1383:     *alocc++ = *in++;
                   1384:   }
                   1385:   if( *in == occ){
                   1386:     *(alocc)='\0';
                   1387:     s=++in;
                   1388:   }
                   1389:  
                   1390:   if (s == t) {/* occ not found */
                   1391:     *(alocc-(in-s))='\0';
                   1392:     in=s;
                   1393:   }
                   1394:   while ( *in != '\0'){
                   1395:     *blocc++ = *in++;
                   1396:   }
                   1397: 
                   1398:   *blocc='\0';
                   1399:   return t;
                   1400: }
1.137     brouard  1401: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1402: {
1.187     brouard  1403:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1404:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1405:      gives blocc="abcdef2ghi" and alocc="j".
                   1406:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1407:   */
                   1408:   char *s, *t;
                   1409:   t=in;s=in;
                   1410:   while (*in != '\0'){
                   1411:     while( *in == occ){
                   1412:       *blocc++ = *in++;
                   1413:       s=in;
                   1414:     }
                   1415:     *blocc++ = *in++;
                   1416:   }
                   1417:   if (s == t) /* occ not found */
                   1418:     *(blocc-(in-s))='\0';
                   1419:   else
                   1420:     *(blocc-(in-s)-1)='\0';
                   1421:   in=s;
                   1422:   while ( *in != '\0'){
                   1423:     *alocc++ = *in++;
                   1424:   }
                   1425: 
                   1426:   *alocc='\0';
                   1427:   return s;
                   1428: }
                   1429: 
1.126     brouard  1430: int nbocc(char *s, char occ)
                   1431: {
                   1432:   int i,j=0;
                   1433:   int lg=20;
                   1434:   i=0;
                   1435:   lg=strlen(s);
                   1436:   for(i=0; i<= lg; i++) {
1.234     brouard  1437:     if  (s[i] == occ ) j++;
1.126     brouard  1438:   }
                   1439:   return j;
                   1440: }
                   1441: 
1.137     brouard  1442: /* void cutv(char *u,char *v, char*t, char occ) */
                   1443: /* { */
                   1444: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1445: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1446: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1447: /*   int i,lg,j,p=0; */
                   1448: /*   i=0; */
                   1449: /*   lg=strlen(t); */
                   1450: /*   for(j=0; j<=lg-1; j++) { */
                   1451: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1452: /*   } */
1.126     brouard  1453: 
1.137     brouard  1454: /*   for(j=0; j<p; j++) { */
                   1455: /*     (u[j] = t[j]); */
                   1456: /*   } */
                   1457: /*      u[p]='\0'; */
1.126     brouard  1458: 
1.137     brouard  1459: /*    for(j=0; j<= lg; j++) { */
                   1460: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1461: /*   } */
                   1462: /* } */
1.126     brouard  1463: 
1.160     brouard  1464: #ifdef _WIN32
                   1465: char * strsep(char **pp, const char *delim)
                   1466: {
                   1467:   char *p, *q;
                   1468:          
                   1469:   if ((p = *pp) == NULL)
                   1470:     return 0;
                   1471:   if ((q = strpbrk (p, delim)) != NULL)
                   1472:   {
                   1473:     *pp = q + 1;
                   1474:     *q = '\0';
                   1475:   }
                   1476:   else
                   1477:     *pp = 0;
                   1478:   return p;
                   1479: }
                   1480: #endif
                   1481: 
1.126     brouard  1482: /********************** nrerror ********************/
                   1483: 
                   1484: void nrerror(char error_text[])
                   1485: {
                   1486:   fprintf(stderr,"ERREUR ...\n");
                   1487:   fprintf(stderr,"%s\n",error_text);
                   1488:   exit(EXIT_FAILURE);
                   1489: }
                   1490: /*********************** vector *******************/
                   1491: double *vector(int nl, int nh)
                   1492: {
                   1493:   double *v;
                   1494:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1495:   if (!v) nrerror("allocation failure in vector");
                   1496:   return v-nl+NR_END;
                   1497: }
                   1498: 
                   1499: /************************ free vector ******************/
                   1500: void free_vector(double*v, int nl, int nh)
                   1501: {
                   1502:   free((FREE_ARG)(v+nl-NR_END));
                   1503: }
                   1504: 
                   1505: /************************ivector *******************************/
                   1506: int *ivector(long nl,long nh)
                   1507: {
                   1508:   int *v;
                   1509:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1510:   if (!v) nrerror("allocation failure in ivector");
                   1511:   return v-nl+NR_END;
                   1512: }
                   1513: 
                   1514: /******************free ivector **************************/
                   1515: void free_ivector(int *v, long nl, long nh)
                   1516: {
                   1517:   free((FREE_ARG)(v+nl-NR_END));
                   1518: }
                   1519: 
                   1520: /************************lvector *******************************/
                   1521: long *lvector(long nl,long nh)
                   1522: {
                   1523:   long *v;
                   1524:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1525:   if (!v) nrerror("allocation failure in ivector");
                   1526:   return v-nl+NR_END;
                   1527: }
                   1528: 
                   1529: /******************free lvector **************************/
                   1530: void free_lvector(long *v, long nl, long nh)
                   1531: {
                   1532:   free((FREE_ARG)(v+nl-NR_END));
                   1533: }
                   1534: 
                   1535: /******************* imatrix *******************************/
                   1536: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1537:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1538: { 
                   1539:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1540:   int **m; 
                   1541:   
                   1542:   /* allocate pointers to rows */ 
                   1543:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1544:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1545:   m += NR_END; 
                   1546:   m -= nrl; 
                   1547:   
                   1548:   
                   1549:   /* allocate rows and set pointers to them */ 
                   1550:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1551:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1552:   m[nrl] += NR_END; 
                   1553:   m[nrl] -= ncl; 
                   1554:   
                   1555:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1556:   
                   1557:   /* return pointer to array of pointers to rows */ 
                   1558:   return m; 
                   1559: } 
                   1560: 
                   1561: /****************** free_imatrix *************************/
                   1562: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1563:       int **m;
                   1564:       long nch,ncl,nrh,nrl; 
                   1565:      /* free an int matrix allocated by imatrix() */ 
                   1566: { 
                   1567:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1568:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1569: } 
                   1570: 
                   1571: /******************* matrix *******************************/
                   1572: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1573: {
                   1574:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1575:   double **m;
                   1576: 
                   1577:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1578:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1579:   m += NR_END;
                   1580:   m -= nrl;
                   1581: 
                   1582:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1583:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1584:   m[nrl] += NR_END;
                   1585:   m[nrl] -= ncl;
                   1586: 
                   1587:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1588:   return m;
1.145     brouard  1589:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1590: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1591: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1592:    */
                   1593: }
                   1594: 
                   1595: /*************************free matrix ************************/
                   1596: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1597: {
                   1598:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1599:   free((FREE_ARG)(m+nrl-NR_END));
                   1600: }
                   1601: 
                   1602: /******************* ma3x *******************************/
                   1603: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1604: {
                   1605:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1606:   double ***m;
                   1607: 
                   1608:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1609:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1610:   m += NR_END;
                   1611:   m -= nrl;
                   1612: 
                   1613:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1614:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1615:   m[nrl] += NR_END;
                   1616:   m[nrl] -= ncl;
                   1617: 
                   1618:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1619: 
                   1620:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1621:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1622:   m[nrl][ncl] += NR_END;
                   1623:   m[nrl][ncl] -= nll;
                   1624:   for (j=ncl+1; j<=nch; j++) 
                   1625:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1626:   
                   1627:   for (i=nrl+1; i<=nrh; i++) {
                   1628:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1629:     for (j=ncl+1; j<=nch; j++) 
                   1630:       m[i][j]=m[i][j-1]+nlay;
                   1631:   }
                   1632:   return m; 
                   1633:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1634:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1635:   */
                   1636: }
                   1637: 
                   1638: /*************************free ma3x ************************/
                   1639: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1640: {
                   1641:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1642:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1643:   free((FREE_ARG)(m+nrl-NR_END));
                   1644: }
                   1645: 
                   1646: /*************** function subdirf ***********/
                   1647: char *subdirf(char fileres[])
                   1648: {
                   1649:   /* Caution optionfilefiname is hidden */
                   1650:   strcpy(tmpout,optionfilefiname);
                   1651:   strcat(tmpout,"/"); /* Add to the right */
                   1652:   strcat(tmpout,fileres);
                   1653:   return tmpout;
                   1654: }
                   1655: 
                   1656: /*************** function subdirf2 ***********/
                   1657: char *subdirf2(char fileres[], char *preop)
                   1658: {
                   1659:   
                   1660:   /* Caution optionfilefiname is hidden */
                   1661:   strcpy(tmpout,optionfilefiname);
                   1662:   strcat(tmpout,"/");
                   1663:   strcat(tmpout,preop);
                   1664:   strcat(tmpout,fileres);
                   1665:   return tmpout;
                   1666: }
                   1667: 
                   1668: /*************** function subdirf3 ***********/
                   1669: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1670: {
                   1671:   
                   1672:   /* Caution optionfilefiname is hidden */
                   1673:   strcpy(tmpout,optionfilefiname);
                   1674:   strcat(tmpout,"/");
                   1675:   strcat(tmpout,preop);
                   1676:   strcat(tmpout,preop2);
                   1677:   strcat(tmpout,fileres);
                   1678:   return tmpout;
                   1679: }
1.213     brouard  1680:  
                   1681: /*************** function subdirfext ***********/
                   1682: char *subdirfext(char fileres[], char *preop, char *postop)
                   1683: {
                   1684:   
                   1685:   strcpy(tmpout,preop);
                   1686:   strcat(tmpout,fileres);
                   1687:   strcat(tmpout,postop);
                   1688:   return tmpout;
                   1689: }
1.126     brouard  1690: 
1.213     brouard  1691: /*************** function subdirfext3 ***********/
                   1692: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1693: {
                   1694:   
                   1695:   /* Caution optionfilefiname is hidden */
                   1696:   strcpy(tmpout,optionfilefiname);
                   1697:   strcat(tmpout,"/");
                   1698:   strcat(tmpout,preop);
                   1699:   strcat(tmpout,fileres);
                   1700:   strcat(tmpout,postop);
                   1701:   return tmpout;
                   1702: }
                   1703:  
1.162     brouard  1704: char *asc_diff_time(long time_sec, char ascdiff[])
                   1705: {
                   1706:   long sec_left, days, hours, minutes;
                   1707:   days = (time_sec) / (60*60*24);
                   1708:   sec_left = (time_sec) % (60*60*24);
                   1709:   hours = (sec_left) / (60*60) ;
                   1710:   sec_left = (sec_left) %(60*60);
                   1711:   minutes = (sec_left) /60;
                   1712:   sec_left = (sec_left) % (60);
                   1713:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1714:   return ascdiff;
                   1715: }
                   1716: 
1.126     brouard  1717: /***************** f1dim *************************/
                   1718: extern int ncom; 
                   1719: extern double *pcom,*xicom;
                   1720: extern double (*nrfunc)(double []); 
                   1721:  
                   1722: double f1dim(double x) 
                   1723: { 
                   1724:   int j; 
                   1725:   double f;
                   1726:   double *xt; 
                   1727:  
                   1728:   xt=vector(1,ncom); 
                   1729:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1730:   f=(*nrfunc)(xt); 
                   1731:   free_vector(xt,1,ncom); 
                   1732:   return f; 
                   1733: } 
                   1734: 
                   1735: /*****************brent *************************/
                   1736: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1737: {
                   1738:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1739:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1740:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1741:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1742:    * returned function value. 
                   1743:   */
1.126     brouard  1744:   int iter; 
                   1745:   double a,b,d,etemp;
1.159     brouard  1746:   double fu=0,fv,fw,fx;
1.164     brouard  1747:   double ftemp=0.;
1.126     brouard  1748:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1749:   double e=0.0; 
                   1750:  
                   1751:   a=(ax < cx ? ax : cx); 
                   1752:   b=(ax > cx ? ax : cx); 
                   1753:   x=w=v=bx; 
                   1754:   fw=fv=fx=(*f)(x); 
                   1755:   for (iter=1;iter<=ITMAX;iter++) { 
                   1756:     xm=0.5*(a+b); 
                   1757:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1758:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1759:     printf(".");fflush(stdout);
                   1760:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1761: #ifdef DEBUGBRENT
1.126     brouard  1762:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1763:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1764:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1765: #endif
                   1766:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1767:       *xmin=x; 
                   1768:       return fx; 
                   1769:     } 
                   1770:     ftemp=fu;
                   1771:     if (fabs(e) > tol1) { 
                   1772:       r=(x-w)*(fx-fv); 
                   1773:       q=(x-v)*(fx-fw); 
                   1774:       p=(x-v)*q-(x-w)*r; 
                   1775:       q=2.0*(q-r); 
                   1776:       if (q > 0.0) p = -p; 
                   1777:       q=fabs(q); 
                   1778:       etemp=e; 
                   1779:       e=d; 
                   1780:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1781:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1782:       else { 
1.224     brouard  1783:                                d=p/q; 
                   1784:                                u=x+d; 
                   1785:                                if (u-a < tol2 || b-u < tol2) 
                   1786:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1787:       } 
                   1788:     } else { 
                   1789:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1790:     } 
                   1791:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1792:     fu=(*f)(u); 
                   1793:     if (fu <= fx) { 
                   1794:       if (u >= x) a=x; else b=x; 
                   1795:       SHFT(v,w,x,u) 
1.183     brouard  1796:       SHFT(fv,fw,fx,fu) 
                   1797:     } else { 
                   1798:       if (u < x) a=u; else b=u; 
                   1799:       if (fu <= fw || w == x) { 
1.224     brouard  1800:                                v=w; 
                   1801:                                w=u; 
                   1802:                                fv=fw; 
                   1803:                                fw=fu; 
1.183     brouard  1804:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1805:                                v=u; 
                   1806:                                fv=fu; 
1.183     brouard  1807:       } 
                   1808:     } 
1.126     brouard  1809:   } 
                   1810:   nrerror("Too many iterations in brent"); 
                   1811:   *xmin=x; 
                   1812:   return fx; 
                   1813: } 
                   1814: 
                   1815: /****************** mnbrak ***********************/
                   1816: 
                   1817: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1818:            double (*func)(double)) 
1.183     brouard  1819: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1820: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1821: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1822: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1823:    */
1.126     brouard  1824:   double ulim,u,r,q, dum;
                   1825:   double fu; 
1.187     brouard  1826: 
                   1827:   double scale=10.;
                   1828:   int iterscale=0;
                   1829: 
                   1830:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1831:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1832: 
                   1833: 
                   1834:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1835:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1836:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1837:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1838:   /* } */
                   1839: 
1.126     brouard  1840:   if (*fb > *fa) { 
                   1841:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1842:     SHFT(dum,*fb,*fa,dum) 
                   1843:   } 
1.126     brouard  1844:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1845:   *fc=(*func)(*cx); 
1.183     brouard  1846: #ifdef DEBUG
1.224     brouard  1847:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1848:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1849: #endif
1.224     brouard  1850:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1851:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1852:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1853:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1854:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1855:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1856:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1857:       fu=(*func)(u); 
1.163     brouard  1858: #ifdef DEBUG
                   1859:       /* f(x)=A(x-u)**2+f(u) */
                   1860:       double A, fparabu; 
                   1861:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1862:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1863:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1864:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1865:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1866:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1867:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1868:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1869: #endif 
1.184     brouard  1870: #ifdef MNBRAKORIGINAL
1.183     brouard  1871: #else
1.191     brouard  1872: /*       if (fu > *fc) { */
                   1873: /* #ifdef DEBUG */
                   1874: /*       printf("mnbrak4  fu > fc \n"); */
                   1875: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1876: /* #endif */
                   1877: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1878: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1879: /*     dum=u; /\* Shifting c and u *\/ */
                   1880: /*     u = *cx; */
                   1881: /*     *cx = dum; */
                   1882: /*     dum = fu; */
                   1883: /*     fu = *fc; */
                   1884: /*     *fc =dum; */
                   1885: /*       } else { /\* end *\/ */
                   1886: /* #ifdef DEBUG */
                   1887: /*       printf("mnbrak3  fu < fc \n"); */
                   1888: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1889: /* #endif */
                   1890: /*     dum=u; /\* Shifting c and u *\/ */
                   1891: /*     u = *cx; */
                   1892: /*     *cx = dum; */
                   1893: /*     dum = fu; */
                   1894: /*     fu = *fc; */
                   1895: /*     *fc =dum; */
                   1896: /*       } */
1.224     brouard  1897: #ifdef DEBUGMNBRAK
                   1898:                 double A, fparabu; 
                   1899:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1900:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1901:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1902:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1903: #endif
1.191     brouard  1904:       dum=u; /* Shifting c and u */
                   1905:       u = *cx;
                   1906:       *cx = dum;
                   1907:       dum = fu;
                   1908:       fu = *fc;
                   1909:       *fc =dum;
1.183     brouard  1910: #endif
1.162     brouard  1911:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1912: #ifdef DEBUG
1.224     brouard  1913:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1914:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1915: #endif
1.126     brouard  1916:       fu=(*func)(u); 
                   1917:       if (fu < *fc) { 
1.183     brouard  1918: #ifdef DEBUG
1.224     brouard  1919:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1920:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1921: #endif
                   1922:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1923:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1924: #ifdef DEBUG
                   1925:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1926: #endif
                   1927:       } 
1.162     brouard  1928:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1929: #ifdef DEBUG
1.224     brouard  1930:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1931:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1932: #endif
1.126     brouard  1933:       u=ulim; 
                   1934:       fu=(*func)(u); 
1.183     brouard  1935:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1936: #ifdef DEBUG
1.224     brouard  1937:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1938:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1939: #endif
1.126     brouard  1940:       u=(*cx)+GOLD*(*cx-*bx); 
                   1941:       fu=(*func)(u); 
1.224     brouard  1942: #ifdef DEBUG
                   1943:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1944:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1945: #endif
1.183     brouard  1946:     } /* end tests */
1.126     brouard  1947:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  1948:     SHFT(*fa,*fb,*fc,fu) 
                   1949: #ifdef DEBUG
1.224     brouard  1950:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   1951:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  1952: #endif
                   1953:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  1954: } 
                   1955: 
                   1956: /*************** linmin ************************/
1.162     brouard  1957: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   1958: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   1959: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   1960: the value of func at the returned location p . This is actually all accomplished by calling the
                   1961: routines mnbrak and brent .*/
1.126     brouard  1962: int ncom; 
                   1963: double *pcom,*xicom;
                   1964: double (*nrfunc)(double []); 
                   1965:  
1.224     brouard  1966: #ifdef LINMINORIGINAL
1.126     brouard  1967: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  1968: #else
                   1969: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   1970: #endif
1.126     brouard  1971: { 
                   1972:   double brent(double ax, double bx, double cx, 
                   1973:               double (*f)(double), double tol, double *xmin); 
                   1974:   double f1dim(double x); 
                   1975:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   1976:              double *fc, double (*func)(double)); 
                   1977:   int j; 
                   1978:   double xx,xmin,bx,ax; 
                   1979:   double fx,fb,fa;
1.187     brouard  1980: 
1.203     brouard  1981: #ifdef LINMINORIGINAL
                   1982: #else
                   1983:   double scale=10., axs, xxs; /* Scale added for infinity */
                   1984: #endif
                   1985:   
1.126     brouard  1986:   ncom=n; 
                   1987:   pcom=vector(1,n); 
                   1988:   xicom=vector(1,n); 
                   1989:   nrfunc=func; 
                   1990:   for (j=1;j<=n;j++) { 
                   1991:     pcom[j]=p[j]; 
1.202     brouard  1992:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  1993:   } 
1.187     brouard  1994: 
1.203     brouard  1995: #ifdef LINMINORIGINAL
                   1996:   xx=1.;
                   1997: #else
                   1998:   axs=0.0;
                   1999:   xxs=1.;
                   2000:   do{
                   2001:     xx= xxs;
                   2002: #endif
1.187     brouard  2003:     ax=0.;
                   2004:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2005:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2006:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2007:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2008:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2009:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2010:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2011: #ifdef LINMINORIGINAL
                   2012: #else
                   2013:     if (fx != fx){
1.224     brouard  2014:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2015:                        printf("|");
                   2016:                        fprintf(ficlog,"|");
1.203     brouard  2017: #ifdef DEBUGLINMIN
1.224     brouard  2018:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2019: #endif
                   2020:     }
1.224     brouard  2021:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2022: #endif
                   2023:   
1.191     brouard  2024: #ifdef DEBUGLINMIN
                   2025:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2026:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2027: #endif
1.224     brouard  2028: #ifdef LINMINORIGINAL
                   2029: #else
                   2030:        if(fb == fx){ /* Flat function in the direction */
                   2031:                xmin=xx;
                   2032:     *flat=1;
                   2033:        }else{
                   2034:     *flat=0;
                   2035: #endif
                   2036:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2037:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2038:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2039:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2040:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2041:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2042: #ifdef DEBUG
1.224     brouard  2043:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2044:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2045: #endif
                   2046: #ifdef LINMINORIGINAL
                   2047: #else
                   2048:                        }
1.126     brouard  2049: #endif
1.191     brouard  2050: #ifdef DEBUGLINMIN
                   2051:   printf("linmin end ");
1.202     brouard  2052:   fprintf(ficlog,"linmin end ");
1.191     brouard  2053: #endif
1.126     brouard  2054:   for (j=1;j<=n;j++) { 
1.203     brouard  2055: #ifdef LINMINORIGINAL
                   2056:     xi[j] *= xmin; 
                   2057: #else
                   2058: #ifdef DEBUGLINMIN
                   2059:     if(xxs <1.0)
                   2060:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2061: #endif
                   2062:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2063: #ifdef DEBUGLINMIN
                   2064:     if(xxs <1.0)
                   2065:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2066: #endif
                   2067: #endif
1.187     brouard  2068:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2069:   } 
1.191     brouard  2070: #ifdef DEBUGLINMIN
1.203     brouard  2071:   printf("\n");
1.191     brouard  2072:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2073:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2074:   for (j=1;j<=n;j++) { 
1.202     brouard  2075:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2076:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2077:     if(j % ncovmodel == 0){
1.191     brouard  2078:       printf("\n");
1.202     brouard  2079:       fprintf(ficlog,"\n");
                   2080:     }
1.191     brouard  2081:   }
1.203     brouard  2082: #else
1.191     brouard  2083: #endif
1.126     brouard  2084:   free_vector(xicom,1,n); 
                   2085:   free_vector(pcom,1,n); 
                   2086: } 
                   2087: 
                   2088: 
                   2089: /*************** powell ************************/
1.162     brouard  2090: /*
                   2091: Minimization of a function func of n variables. Input consists of an initial starting point
                   2092: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2093: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2094: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2095: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2096: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2097:  */
1.224     brouard  2098: #ifdef LINMINORIGINAL
                   2099: #else
                   2100:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2101:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2102: #endif
1.126     brouard  2103: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2104:            double (*func)(double [])) 
                   2105: { 
1.224     brouard  2106: #ifdef LINMINORIGINAL
                   2107:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2108:              double (*func)(double [])); 
1.224     brouard  2109: #else 
1.241     brouard  2110:  void linmin(double p[], double xi[], int n, double *fret,
                   2111:             double (*func)(double []),int *flat); 
1.224     brouard  2112: #endif
1.239     brouard  2113:  int i,ibig,j,jk,k; 
1.126     brouard  2114:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2115:   double directest;
1.126     brouard  2116:   double fp,fptt;
                   2117:   double *xits;
                   2118:   int niterf, itmp;
1.224     brouard  2119: #ifdef LINMINORIGINAL
                   2120: #else
                   2121: 
                   2122:   flatdir=ivector(1,n); 
                   2123:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2124: #endif
1.126     brouard  2125: 
                   2126:   pt=vector(1,n); 
                   2127:   ptt=vector(1,n); 
                   2128:   xit=vector(1,n); 
                   2129:   xits=vector(1,n); 
                   2130:   *fret=(*func)(p); 
                   2131:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2132:   rcurr_time = time(NULL);  
1.126     brouard  2133:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2134:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2135:     ibig=0; 
                   2136:     del=0.0; 
1.157     brouard  2137:     rlast_time=rcurr_time;
                   2138:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2139:     rcurr_time = time(NULL);  
                   2140:     curr_time = *localtime(&rcurr_time);
                   2141:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2142:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2143: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2144:     for (i=1;i<=n;i++) {
1.126     brouard  2145:       fprintf(ficrespow," %.12lf", p[i]);
                   2146:     }
1.239     brouard  2147:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2148:     printf("\n#model=  1      +     age ");
                   2149:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2150:     if(nagesqr==1){
1.241     brouard  2151:        printf("  + age*age  ");
                   2152:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2153:     }
                   2154:     for(j=1;j <=ncovmodel-2;j++){
                   2155:       if(Typevar[j]==0) {
                   2156:        printf("  +      V%d  ",Tvar[j]);
                   2157:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2158:       }else if(Typevar[j]==1) {
                   2159:        printf("  +    V%d*age ",Tvar[j]);
                   2160:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2161:       }else if(Typevar[j]==2) {
                   2162:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2163:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2164:       }
                   2165:     }
1.126     brouard  2166:     printf("\n");
1.239     brouard  2167: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2168: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2169:     fprintf(ficlog,"\n");
1.239     brouard  2170:     for(i=1,jk=1; i <=nlstate; i++){
                   2171:       for(k=1; k <=(nlstate+ndeath); k++){
                   2172:        if (k != i) {
                   2173:          printf("%d%d ",i,k);
                   2174:          fprintf(ficlog,"%d%d ",i,k);
                   2175:          for(j=1; j <=ncovmodel; j++){
                   2176:            printf("%12.7f ",p[jk]);
                   2177:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2178:            jk++; 
                   2179:          }
                   2180:          printf("\n");
                   2181:          fprintf(ficlog,"\n");
                   2182:        }
                   2183:       }
                   2184:     }
1.241     brouard  2185:     if(*iter <=3 && *iter >1){
1.157     brouard  2186:       tml = *localtime(&rcurr_time);
                   2187:       strcpy(strcurr,asctime(&tml));
                   2188:       rforecast_time=rcurr_time; 
1.126     brouard  2189:       itmp = strlen(strcurr);
                   2190:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2191:        strcurr[itmp-1]='\0';
1.162     brouard  2192:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2193:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2194:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2195:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2196:        forecast_time = *localtime(&rforecast_time);
                   2197:        strcpy(strfor,asctime(&forecast_time));
                   2198:        itmp = strlen(strfor);
                   2199:        if(strfor[itmp-1]=='\n')
                   2200:          strfor[itmp-1]='\0';
                   2201:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2202:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2203:       }
                   2204:     }
1.187     brouard  2205:     for (i=1;i<=n;i++) { /* For each direction i */
                   2206:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2207:       fptt=(*fret); 
                   2208: #ifdef DEBUG
1.203     brouard  2209:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2210:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2211: #endif
1.203     brouard  2212:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2213:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2214: #ifdef LINMINORIGINAL
1.188     brouard  2215:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2216: #else
                   2217:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2218:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2219: #endif
                   2220:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2221:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2222:                                /* because that direction will be replaced unless the gain del is small */
                   2223:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2224:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2225:                                /* with the new direction. */
                   2226:                                del=fabs(fptt-(*fret)); 
                   2227:                                ibig=i; 
1.126     brouard  2228:       } 
                   2229: #ifdef DEBUG
                   2230:       printf("%d %.12e",i,(*fret));
                   2231:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2232:       for (j=1;j<=n;j++) {
1.224     brouard  2233:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2234:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2235:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2236:       }
                   2237:       for(j=1;j<=n;j++) {
1.225     brouard  2238:                                printf(" p(%d)=%.12e",j,p[j]);
                   2239:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2240:       }
                   2241:       printf("\n");
                   2242:       fprintf(ficlog,"\n");
                   2243: #endif
1.187     brouard  2244:     } /* end loop on each direction i */
                   2245:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2246:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2247:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2248:       for(j=1;j<=n;j++) {
1.225     brouard  2249:                                if(flatdir[j] >0){
                   2250:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2251:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2252:                                }
                   2253:                                /* printf("\n"); */
                   2254:                                /* fprintf(ficlog,"\n"); */
                   2255:                        }
1.243     brouard  2256:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2257:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2258:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2259:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2260:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2261:       /* decreased of more than 3.84  */
                   2262:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2263:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2264:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2265:                        
1.188     brouard  2266:       /* Starting the program with initial values given by a former maximization will simply change */
                   2267:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2268:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2269:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2270: #ifdef DEBUG
                   2271:       int k[2],l;
                   2272:       k[0]=1;
                   2273:       k[1]=-1;
                   2274:       printf("Max: %.12e",(*func)(p));
                   2275:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2276:       for (j=1;j<=n;j++) {
                   2277:        printf(" %.12e",p[j]);
                   2278:        fprintf(ficlog," %.12e",p[j]);
                   2279:       }
                   2280:       printf("\n");
                   2281:       fprintf(ficlog,"\n");
                   2282:       for(l=0;l<=1;l++) {
                   2283:        for (j=1;j<=n;j++) {
                   2284:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2285:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2286:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2287:        }
                   2288:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2289:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2290:       }
                   2291: #endif
                   2292: 
1.224     brouard  2293: #ifdef LINMINORIGINAL
                   2294: #else
                   2295:       free_ivector(flatdir,1,n); 
                   2296: #endif
1.126     brouard  2297:       free_vector(xit,1,n); 
                   2298:       free_vector(xits,1,n); 
                   2299:       free_vector(ptt,1,n); 
                   2300:       free_vector(pt,1,n); 
                   2301:       return; 
1.192     brouard  2302:     } /* enough precision */ 
1.240     brouard  2303:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2304:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2305:       ptt[j]=2.0*p[j]-pt[j]; 
                   2306:       xit[j]=p[j]-pt[j]; 
                   2307:       pt[j]=p[j]; 
                   2308:     } 
1.181     brouard  2309:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2310: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2311:                if (*iter <=4) {
1.225     brouard  2312: #else
                   2313: #endif
1.224     brouard  2314: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2315: #else
1.161     brouard  2316:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2317: #endif
1.162     brouard  2318:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2319:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2320:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2321:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2322:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2323:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2324:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2325:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2326:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2327:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2328:       /* mu² and del² are equal when f3=f1 */
                   2329:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2330:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2331:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2332:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2333: #ifdef NRCORIGINAL
                   2334:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2335: #else
                   2336:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2337:       t= t- del*SQR(fp-fptt);
1.183     brouard  2338: #endif
1.202     brouard  2339:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2340: #ifdef DEBUG
1.181     brouard  2341:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2342:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2343:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2344:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2345:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2346:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2347:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2348:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2349: #endif
1.183     brouard  2350: #ifdef POWELLORIGINAL
                   2351:       if (t < 0.0) { /* Then we use it for new direction */
                   2352: #else
1.182     brouard  2353:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2354:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2355:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2356:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2357:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2358:       } 
1.181     brouard  2359:       if (directest < 0.0) { /* Then we use it for new direction */
                   2360: #endif
1.191     brouard  2361: #ifdef DEBUGLINMIN
1.234     brouard  2362:        printf("Before linmin in direction P%d-P0\n",n);
                   2363:        for (j=1;j<=n;j++) {
                   2364:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2365:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2366:          if(j % ncovmodel == 0){
                   2367:            printf("\n");
                   2368:            fprintf(ficlog,"\n");
                   2369:          }
                   2370:        }
1.224     brouard  2371: #endif
                   2372: #ifdef LINMINORIGINAL
1.234     brouard  2373:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2374: #else
1.234     brouard  2375:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2376:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2377: #endif
1.234     brouard  2378:        
1.191     brouard  2379: #ifdef DEBUGLINMIN
1.234     brouard  2380:        for (j=1;j<=n;j++) { 
                   2381:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2382:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2383:          if(j % ncovmodel == 0){
                   2384:            printf("\n");
                   2385:            fprintf(ficlog,"\n");
                   2386:          }
                   2387:        }
1.224     brouard  2388: #endif
1.234     brouard  2389:        for (j=1;j<=n;j++) { 
                   2390:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2391:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2392:        }
1.224     brouard  2393: #ifdef LINMINORIGINAL
                   2394: #else
1.234     brouard  2395:        for (j=1, flatd=0;j<=n;j++) {
                   2396:          if(flatdir[j]>0)
                   2397:            flatd++;
                   2398:        }
                   2399:        if(flatd >0){
                   2400:          printf("%d flat directions\n",flatd);
                   2401:          fprintf(ficlog,"%d flat directions\n",flatd);
                   2402:          for (j=1;j<=n;j++) { 
                   2403:            if(flatdir[j]>0){
                   2404:              printf("%d ",j);
                   2405:              fprintf(ficlog,"%d ",j);
                   2406:            }
                   2407:          }
                   2408:          printf("\n");
                   2409:          fprintf(ficlog,"\n");
                   2410:        }
1.191     brouard  2411: #endif
1.234     brouard  2412:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2413:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2414:        
1.126     brouard  2415: #ifdef DEBUG
1.234     brouard  2416:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2417:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2418:        for(j=1;j<=n;j++){
                   2419:          printf(" %lf",xit[j]);
                   2420:          fprintf(ficlog," %lf",xit[j]);
                   2421:        }
                   2422:        printf("\n");
                   2423:        fprintf(ficlog,"\n");
1.126     brouard  2424: #endif
1.192     brouard  2425:       } /* end of t or directest negative */
1.224     brouard  2426: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2427: #else
1.234     brouard  2428:       } /* end if (fptt < fp)  */
1.192     brouard  2429: #endif
1.225     brouard  2430: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2431:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2432: #else
1.224     brouard  2433: #endif
1.234     brouard  2434:                } /* loop iteration */ 
1.126     brouard  2435: } 
1.234     brouard  2436:   
1.126     brouard  2437: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2438:   
1.235     brouard  2439:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2440:   {
1.235     brouard  2441:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2442:        (and selected quantitative values in nres)
                   2443:        by left multiplying the unit
1.234     brouard  2444:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2445:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2446:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2447:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2448:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2449:   /* Initial matrix pimij */
                   2450:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2451:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2452:   /*  0,                   0                  , 1} */
                   2453:   /*
                   2454:    * and after some iteration: */
                   2455:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2456:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2457:   /*  0,                   0                  , 1} */
                   2458:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2459:   /* {0.51571254859325999, 0.4842874514067399, */
                   2460:   /*  0.51326036147820708, 0.48673963852179264} */
                   2461:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2462:     
1.126     brouard  2463:   int i, ii,j,k;
1.209     brouard  2464:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2465:   /* double **matprod2(); */ /* test */
1.218     brouard  2466:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2467:   double **newm;
1.209     brouard  2468:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2469:   int ncvloop=0;
1.169     brouard  2470:   
1.209     brouard  2471:   min=vector(1,nlstate);
                   2472:   max=vector(1,nlstate);
                   2473:   meandiff=vector(1,nlstate);
                   2474: 
1.218     brouard  2475:        /* Starting with matrix unity */
1.126     brouard  2476:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2477:     for (j=1;j<=nlstate+ndeath;j++){
                   2478:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2479:     }
1.169     brouard  2480:   
                   2481:   cov[1]=1.;
                   2482:   
                   2483:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2484:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2485:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2486:     ncvloop++;
1.126     brouard  2487:     newm=savm;
                   2488:     /* Covariates have to be included here again */
1.138     brouard  2489:     cov[2]=agefin;
1.187     brouard  2490:     if(nagesqr==1)
                   2491:       cov[3]= agefin*agefin;;
1.234     brouard  2492:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2493:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2494:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2495:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2496:     }
                   2497:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2498:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2499:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2500:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2501:     }
1.237     brouard  2502:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2503:       if(Dummy[Tvar[Tage[k]]]){
                   2504:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2505:       } else{
1.235     brouard  2506:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2507:       }
1.235     brouard  2508:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2509:     }
1.237     brouard  2510:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2511:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2512:       if(Dummy[Tvard[k][1]==0]){
                   2513:        if(Dummy[Tvard[k][2]==0]){
                   2514:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2515:        }else{
                   2516:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2517:        }
                   2518:       }else{
                   2519:        if(Dummy[Tvard[k][2]==0]){
                   2520:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2521:        }else{
                   2522:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2523:        }
                   2524:       }
1.234     brouard  2525:     }
1.138     brouard  2526:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2527:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2528:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2529:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2530:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2531:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2532:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2533:     
1.126     brouard  2534:     savm=oldm;
                   2535:     oldm=newm;
1.209     brouard  2536: 
                   2537:     for(j=1; j<=nlstate; j++){
                   2538:       max[j]=0.;
                   2539:       min[j]=1.;
                   2540:     }
                   2541:     for(i=1;i<=nlstate;i++){
                   2542:       sumnew=0;
                   2543:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2544:       for(j=1; j<=nlstate; j++){ 
                   2545:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2546:        max[j]=FMAX(max[j],prlim[i][j]);
                   2547:        min[j]=FMIN(min[j],prlim[i][j]);
                   2548:       }
                   2549:     }
                   2550: 
1.126     brouard  2551:     maxmax=0.;
1.209     brouard  2552:     for(j=1; j<=nlstate; j++){
                   2553:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2554:       maxmax=FMAX(maxmax,meandiff[j]);
                   2555:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2556:     } /* j loop */
1.203     brouard  2557:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2558:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2559:     if(maxmax < ftolpl){
1.209     brouard  2560:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2561:       free_vector(min,1,nlstate);
                   2562:       free_vector(max,1,nlstate);
                   2563:       free_vector(meandiff,1,nlstate);
1.126     brouard  2564:       return prlim;
                   2565:     }
1.169     brouard  2566:   } /* age loop */
1.208     brouard  2567:     /* After some age loop it doesn't converge */
1.209     brouard  2568:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2569: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2570:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2571:   free_vector(min,1,nlstate);
                   2572:   free_vector(max,1,nlstate);
                   2573:   free_vector(meandiff,1,nlstate);
1.208     brouard  2574:   
1.169     brouard  2575:   return prlim; /* should not reach here */
1.126     brouard  2576: }
                   2577: 
1.217     brouard  2578: 
                   2579:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2580: 
1.218     brouard  2581:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2582:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2583:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2584: {
1.218     brouard  2585:   /* Computes the prevalence limit in each live state at age x and covariate ij by left multiplying the unit
1.217     brouard  2586:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2587:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2588:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2589:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2590:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2591:   /* Initial matrix pimij */
                   2592:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2593:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2594:   /*  0,                   0                  , 1} */
                   2595:   /*
                   2596:    * and after some iteration: */
                   2597:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2598:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2599:   /*  0,                   0                  , 1} */
                   2600:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2601:   /* {0.51571254859325999, 0.4842874514067399, */
                   2602:   /*  0.51326036147820708, 0.48673963852179264} */
                   2603:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2604: 
                   2605:   int i, ii,j,k;
1.247     brouard  2606:   int first=0;
1.217     brouard  2607:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2608:   /* double **matprod2(); */ /* test */
                   2609:   double **out, cov[NCOVMAX+1], **bmij();
                   2610:   double **newm;
1.218     brouard  2611:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2612:   double        **oldm, **savm;  /* for use */
                   2613: 
1.217     brouard  2614:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2615:   int ncvloop=0;
                   2616:   
                   2617:   min=vector(1,nlstate);
                   2618:   max=vector(1,nlstate);
                   2619:   meandiff=vector(1,nlstate);
                   2620: 
1.218     brouard  2621:        dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2622:        oldm=oldms; savm=savms;
                   2623: 
                   2624:        /* Starting with matrix unity */
                   2625:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   2626:                for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2627:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2628:     }
                   2629:   
                   2630:   cov[1]=1.;
                   2631:   
                   2632:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2633:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2634:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2635:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2636:     ncvloop++;
1.218     brouard  2637:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2638:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2639:     /* Covariates have to be included here again */
                   2640:     cov[2]=agefin;
                   2641:     if(nagesqr==1)
                   2642:       cov[3]= agefin*agefin;;
1.242     brouard  2643:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2644:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2645:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   2646:       /* printf("bprevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   2647:     }
                   2648:     /* for (k=1; k<=cptcovn;k++) { */
                   2649:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2650:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2651:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2652:     /* } */
                   2653:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2654:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2655:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2656:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2657:     }
                   2658:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2659:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2660:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2661:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2662:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2663:       if(Dummy[Tvar[Tage[k]]]){
                   2664:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2665:       } else{
                   2666:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2667:       }
                   2668:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2669:     }
                   2670:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2671:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2672:       if(Dummy[Tvard[k][1]==0]){
                   2673:        if(Dummy[Tvard[k][2]==0]){
                   2674:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2675:        }else{
                   2676:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2677:        }
                   2678:       }else{
                   2679:        if(Dummy[Tvard[k][2]==0]){
                   2680:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2681:        }else{
                   2682:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2683:        }
                   2684:       }
1.217     brouard  2685:     }
                   2686:     
                   2687:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2688:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2689:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2690:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2691:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2692:                /* ij should be linked to the correct index of cov */
                   2693:                /* age and covariate values ij are in 'cov', but we need to pass
                   2694:                 * ij for the observed prevalence at age and status and covariate
                   2695:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2696:                 */
                   2697:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2698:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2699:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.217     brouard  2700:     savm=oldm;
                   2701:     oldm=newm;
                   2702:     for(j=1; j<=nlstate; j++){
                   2703:       max[j]=0.;
                   2704:       min[j]=1.;
                   2705:     }
                   2706:     for(j=1; j<=nlstate; j++){ 
                   2707:       for(i=1;i<=nlstate;i++){
1.234     brouard  2708:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2709:        bprlim[i][j]= newm[i][j];
                   2710:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2711:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2712:       }
                   2713:     }
1.218     brouard  2714:                
1.217     brouard  2715:     maxmax=0.;
                   2716:     for(i=1; i<=nlstate; i++){
                   2717:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2718:       maxmax=FMAX(maxmax,meandiff[i]);
                   2719:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
                   2720:     } /* j loop */
                   2721:     *ncvyear= -( (int)age- (int)agefin);
1.218     brouard  2722:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear);*/
1.217     brouard  2723:     if(maxmax < ftolpl){
1.220     brouard  2724:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2725:       free_vector(min,1,nlstate);
                   2726:       free_vector(max,1,nlstate);
                   2727:       free_vector(meandiff,1,nlstate);
                   2728:       return bprlim;
                   2729:     }
                   2730:   } /* age loop */
                   2731:     /* After some age loop it doesn't converge */
1.247     brouard  2732:   if(first){
                   2733:     first=1;
                   2734:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2735: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2736:   }
                   2737:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2738: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2739:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2740:   free_vector(min,1,nlstate);
                   2741:   free_vector(max,1,nlstate);
                   2742:   free_vector(meandiff,1,nlstate);
                   2743:   
                   2744:   return bprlim; /* should not reach here */
                   2745: }
                   2746: 
1.126     brouard  2747: /*************** transition probabilities ***************/ 
                   2748: 
                   2749: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2750: {
1.138     brouard  2751:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2752:      computes the probability to be observed in state j being in state i by appying the
                   2753:      model to the ncovmodel covariates (including constant and age).
                   2754:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2755:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2756:      ncth covariate in the global vector x is given by the formula:
                   2757:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2758:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2759:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2760:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2761:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2762:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2763:   */
                   2764:   double s1, lnpijopii;
1.126     brouard  2765:   /*double t34;*/
1.164     brouard  2766:   int i,j, nc, ii, jj;
1.126     brouard  2767: 
1.223     brouard  2768:   for(i=1; i<= nlstate; i++){
                   2769:     for(j=1; j<i;j++){
                   2770:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2771:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2772:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2773:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2774:       }
                   2775:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2776:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2777:     }
                   2778:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2779:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2780:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2781:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2782:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2783:       }
                   2784:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2785:     }
                   2786:   }
1.218     brouard  2787:   
1.223     brouard  2788:   for(i=1; i<= nlstate; i++){
                   2789:     s1=0;
                   2790:     for(j=1; j<i; j++){
                   2791:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2792:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2793:     }
                   2794:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2795:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2796:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2797:     }
                   2798:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2799:     ps[i][i]=1./(s1+1.);
                   2800:     /* Computing other pijs */
                   2801:     for(j=1; j<i; j++)
                   2802:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2803:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2804:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2805:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2806:   } /* end i */
1.218     brouard  2807:   
1.223     brouard  2808:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2809:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2810:       ps[ii][jj]=0;
                   2811:       ps[ii][ii]=1;
                   2812:     }
                   2813:   }
1.218     brouard  2814:   
                   2815:   
1.223     brouard  2816:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2817:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2818:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2819:   /*   } */
                   2820:   /*   printf("\n "); */
                   2821:   /* } */
                   2822:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2823:   /*
                   2824:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2825:                goto end;*/
1.223     brouard  2826:   return ps;
1.126     brouard  2827: }
                   2828: 
1.218     brouard  2829: /*************** backward transition probabilities ***************/ 
                   2830: 
                   2831:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2832: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2833:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2834: {
1.222     brouard  2835:   /* Computes the backward probability at age agefin and covariate ij
                   2836:    * and returns in **ps as well as **bmij.
                   2837:    */
1.218     brouard  2838:   int i, ii, j,k;
1.222     brouard  2839:   
                   2840:   double **out, **pmij();
                   2841:   double sumnew=0.;
1.218     brouard  2842:   double agefin;
1.222     brouard  2843:   
                   2844:   double **dnewm, **dsavm, **doldm;
                   2845:   double **bbmij;
                   2846:   
1.218     brouard  2847:   doldm=ddoldms; /* global pointers */
1.222     brouard  2848:   dnewm=ddnewms;
                   2849:   dsavm=ddsavms;
                   2850:   
                   2851:   agefin=cov[2];
                   2852:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
                   2853:      the observed prevalence (with this covariate ij) */
                   2854:   dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate);
                   2855:   /* We do have the matrix Px in savm  and we need pij */
                   2856:   for (j=1;j<=nlstate+ndeath;j++){
                   2857:     sumnew=0.; /* w1 p11 + w2 p21 only on live states */
                   2858:     for (ii=1;ii<=nlstate;ii++){
                   2859:       sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij];
                   2860:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
                   2861:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2862:       if(sumnew >= 1.e-10){
                   2863:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
                   2864:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2865:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
                   2866:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2867:        /* }else */
                   2868:        doldm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2869:       }else{
1.242     brouard  2870:        ;
                   2871:        /* printf("ii=%d, i=%d, doldm=%lf dsavm=%lf, probs=%lf, sumnew=%lf,agefin=%d\n",ii,j,doldm[ii][j],dsavm[ii][j],prevacurrent[(int)agefin][ii][ij],sumnew, (int)agefin); */
1.222     brouard  2872:       }
                   2873:     } /*End ii */
                   2874:   } /* End j, At the end doldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2875:   /* left Product of this diag matrix by dsavm=Px (newm=dsavm*doldm) */
                   2876:   bbmij=matprod2(dnewm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, doldm); /* Bug Valgrind */
                   2877:   /* dsavm=doldm; /\* dsavm is now diag [1/(w_1p1i+w_2 p2i)] but can be overwritten*\/ */
                   2878:   /* doldm=dnewm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2879:   /* dnewm=dsavm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2880:   /* left Product of this matrix by diag matrix of prevalences (savm) */
                   2881:   for (j=1;j<=nlstate+ndeath;j++){
                   2882:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2883:       dsavm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij] : 0.0);
                   2884:     }
                   2885:   } /* End j, At the end oldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2886:   ps=matprod2(doldm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dnewm); /* Bug Valgrind */
                   2887:   /* newm or out is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
                   2888:   /* end bmij */
                   2889:   return ps; 
1.218     brouard  2890: }
1.217     brouard  2891: /*************** transition probabilities ***************/ 
                   2892: 
1.218     brouard  2893: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2894: {
                   2895:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2896:      computes the probability to be observed in state j being in state i by appying the
                   2897:      model to the ncovmodel covariates (including constant and age).
                   2898:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2899:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2900:      ncth covariate in the global vector x is given by the formula:
                   2901:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2902:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2903:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2904:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2905:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2906:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2907:   */
                   2908:   double s1, lnpijopii;
                   2909:   /*double t34;*/
                   2910:   int i,j, nc, ii, jj;
                   2911: 
1.234     brouard  2912:   for(i=1; i<= nlstate; i++){
                   2913:     for(j=1; j<i;j++){
                   2914:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2915:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2916:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2917:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2918:       }
                   2919:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2920:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2921:     }
                   2922:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2923:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2924:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2925:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2926:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2927:       }
                   2928:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2929:     }
                   2930:   }
                   2931:   
                   2932:   for(i=1; i<= nlstate; i++){
                   2933:     s1=0;
                   2934:     for(j=1; j<i; j++){
                   2935:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2936:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2937:     }
                   2938:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2939:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2940:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2941:     }
                   2942:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2943:     ps[i][i]=1./(s1+1.);
                   2944:     /* Computing other pijs */
                   2945:     for(j=1; j<i; j++)
                   2946:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2947:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2948:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2949:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2950:   } /* end i */
                   2951:   
                   2952:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2953:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2954:       ps[ii][jj]=0;
                   2955:       ps[ii][ii]=1;
                   2956:     }
                   2957:   }
                   2958:   /* Added for backcast */ /* Transposed matrix too */
                   2959:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2960:     s1=0.;
                   2961:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   2962:       s1+=ps[ii][jj];
                   2963:     }
                   2964:     for(ii=1; ii<= nlstate; ii++){
                   2965:       ps[ii][jj]=ps[ii][jj]/s1;
                   2966:     }
                   2967:   }
                   2968:   /* Transposition */
                   2969:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2970:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   2971:       s1=ps[ii][jj];
                   2972:       ps[ii][jj]=ps[jj][ii];
                   2973:       ps[jj][ii]=s1;
                   2974:     }
                   2975:   }
                   2976:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2977:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2978:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2979:   /*   } */
                   2980:   /*   printf("\n "); */
                   2981:   /* } */
                   2982:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2983:   /*
                   2984:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   2985:     goto end;*/
                   2986:   return ps;
1.217     brouard  2987: }
                   2988: 
                   2989: 
1.126     brouard  2990: /**************** Product of 2 matrices ******************/
                   2991: 
1.145     brouard  2992: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  2993: {
                   2994:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   2995:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   2996:   /* in, b, out are matrice of pointers which should have been initialized 
                   2997:      before: only the contents of out is modified. The function returns
                   2998:      a pointer to pointers identical to out */
1.145     brouard  2999:   int i, j, k;
1.126     brouard  3000:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3001:     for(k=ncolol; k<=ncoloh; k++){
                   3002:       out[i][k]=0.;
                   3003:       for(j=ncl; j<=nch; j++)
                   3004:        out[i][k] +=in[i][j]*b[j][k];
                   3005:     }
1.126     brouard  3006:   return out;
                   3007: }
                   3008: 
                   3009: 
                   3010: /************* Higher Matrix Product ***************/
                   3011: 
1.235     brouard  3012: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3013: {
1.218     brouard  3014:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3015:      'nhstepm*hstepm*stepm' months (i.e. until
                   3016:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3017:      nhstepm*hstepm matrices. 
                   3018:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3019:      (typically every 2 years instead of every month which is too big 
                   3020:      for the memory).
                   3021:      Model is determined by parameters x and covariates have to be 
                   3022:      included manually here. 
                   3023: 
                   3024:      */
                   3025: 
                   3026:   int i, j, d, h, k;
1.131     brouard  3027:   double **out, cov[NCOVMAX+1];
1.126     brouard  3028:   double **newm;
1.187     brouard  3029:   double agexact;
1.214     brouard  3030:   double agebegin, ageend;
1.126     brouard  3031: 
                   3032:   /* Hstepm could be zero and should return the unit matrix */
                   3033:   for (i=1;i<=nlstate+ndeath;i++)
                   3034:     for (j=1;j<=nlstate+ndeath;j++){
                   3035:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3036:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3037:     }
                   3038:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3039:   for(h=1; h <=nhstepm; h++){
                   3040:     for(d=1; d <=hstepm; d++){
                   3041:       newm=savm;
                   3042:       /* Covariates have to be included here again */
                   3043:       cov[1]=1.;
1.214     brouard  3044:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3045:       cov[2]=agexact;
                   3046:       if(nagesqr==1)
1.227     brouard  3047:        cov[3]= agexact*agexact;
1.235     brouard  3048:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3049:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3050:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3051:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3052:       }
                   3053:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3054:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3055:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3056:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3057:       }
                   3058:       for (k=1; k<=cptcovage;k++){
                   3059:        if(Dummy[Tvar[Tage[k]]]){
                   3060:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3061:        } else{
                   3062:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3063:        }
                   3064:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3065:       }
                   3066:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3067:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3068:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3069:       }
                   3070:       /* for (k=1; k<=cptcovn;k++)  */
                   3071:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3072:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3073:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3074:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3075:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3076:       
                   3077:       
1.126     brouard  3078:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3079:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3080:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3081:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3082:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3083:       /* if((int)age == 70){ */
                   3084:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3085:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3086:       /*         printf("%d pmmij ",i); */
                   3087:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3088:       /*           printf("%f ",pmmij[i][j]); */
                   3089:       /*         } */
                   3090:       /*         printf(" oldm "); */
                   3091:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3092:       /*           printf("%f ",oldm[i][j]); */
                   3093:       /*         } */
                   3094:       /*         printf("\n"); */
                   3095:       /*       } */
                   3096:       /* } */
1.126     brouard  3097:       savm=oldm;
                   3098:       oldm=newm;
                   3099:     }
                   3100:     for(i=1; i<=nlstate+ndeath; i++)
                   3101:       for(j=1;j<=nlstate+ndeath;j++) {
1.218     brouard  3102:                                po[i][j][h]=newm[i][j];
                   3103:                                /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3104:       }
1.128     brouard  3105:     /*printf("h=%d ",h);*/
1.126     brouard  3106:   } /* end h */
1.218     brouard  3107:        /*     printf("\n H=%d \n",h); */
1.126     brouard  3108:   return po;
                   3109: }
                   3110: 
1.217     brouard  3111: /************* Higher Back Matrix Product ***************/
1.218     brouard  3112: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.222     brouard  3113: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij )
1.217     brouard  3114: {
1.218     brouard  3115:   /* Computes the transition matrix starting at age 'age' over
1.217     brouard  3116:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3117:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3118:      nhstepm*hstepm matrices.
                   3119:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3120:      (typically every 2 years instead of every month which is too big
1.217     brouard  3121:      for the memory).
1.218     brouard  3122:      Model is determined by parameters x and covariates have to be
                   3123:      included manually here.
1.217     brouard  3124: 
1.222     brouard  3125:   */
1.217     brouard  3126: 
                   3127:   int i, j, d, h, k;
                   3128:   double **out, cov[NCOVMAX+1];
                   3129:   double **newm;
                   3130:   double agexact;
                   3131:   double agebegin, ageend;
1.222     brouard  3132:   double **oldm, **savm;
1.217     brouard  3133: 
1.222     brouard  3134:   oldm=oldms;savm=savms;
1.217     brouard  3135:   /* Hstepm could be zero and should return the unit matrix */
                   3136:   for (i=1;i<=nlstate+ndeath;i++)
                   3137:     for (j=1;j<=nlstate+ndeath;j++){
                   3138:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3139:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3140:     }
                   3141:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3142:   for(h=1; h <=nhstepm; h++){
                   3143:     for(d=1; d <=hstepm; d++){
                   3144:       newm=savm;
                   3145:       /* Covariates have to be included here again */
                   3146:       cov[1]=1.;
                   3147:       agexact=age-((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
                   3148:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3149:       cov[2]=agexact;
                   3150:       if(nagesqr==1)
1.222     brouard  3151:        cov[3]= agexact*agexact;
1.218     brouard  3152:       for (k=1; k<=cptcovn;k++)
1.222     brouard  3153:        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   3154:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.217     brouard  3155:       for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
1.222     brouard  3156:        /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   3157:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3158:       /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
1.217     brouard  3159:       for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
1.222     brouard  3160:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3161:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
1.218     brouard  3162:                        
                   3163:                        
1.217     brouard  3164:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3165:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3166:       /* Careful transposed matrix */
1.222     brouard  3167:       /* age is in cov[2] */
1.218     brouard  3168:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3169:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3170:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3171:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3172:       /* if((int)age == 70){ */
                   3173:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3174:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3175:       /*         printf("%d pmmij ",i); */
                   3176:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3177:       /*           printf("%f ",pmmij[i][j]); */
                   3178:       /*         } */
                   3179:       /*         printf(" oldm "); */
                   3180:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3181:       /*           printf("%f ",oldm[i][j]); */
                   3182:       /*         } */
                   3183:       /*         printf("\n"); */
                   3184:       /*       } */
                   3185:       /* } */
                   3186:       savm=oldm;
                   3187:       oldm=newm;
                   3188:     }
                   3189:     for(i=1; i<=nlstate+ndeath; i++)
                   3190:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3191:        po[i][j][h]=newm[i][j];
                   3192:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.217     brouard  3193:       }
                   3194:     /*printf("h=%d ",h);*/
                   3195:   } /* end h */
1.222     brouard  3196:   /*     printf("\n H=%d \n",h); */
1.217     brouard  3197:   return po;
                   3198: }
                   3199: 
                   3200: 
1.162     brouard  3201: #ifdef NLOPT
                   3202:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3203:   double fret;
                   3204:   double *xt;
                   3205:   int j;
                   3206:   myfunc_data *d2 = (myfunc_data *) pd;
                   3207: /* xt = (p1-1); */
                   3208:   xt=vector(1,n); 
                   3209:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3210: 
                   3211:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3212:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3213:   printf("Function = %.12lf ",fret);
                   3214:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3215:   printf("\n");
                   3216:  free_vector(xt,1,n);
                   3217:   return fret;
                   3218: }
                   3219: #endif
1.126     brouard  3220: 
                   3221: /*************** log-likelihood *************/
                   3222: double func( double *x)
                   3223: {
1.226     brouard  3224:   int i, ii, j, k, mi, d, kk;
                   3225:   int ioffset=0;
                   3226:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3227:   double **out;
                   3228:   double lli; /* Individual log likelihood */
                   3229:   int s1, s2;
1.228     brouard  3230:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3231:   double bbh, survp;
                   3232:   long ipmx;
                   3233:   double agexact;
                   3234:   /*extern weight */
                   3235:   /* We are differentiating ll according to initial status */
                   3236:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3237:   /*for(i=1;i<imx;i++) 
                   3238:     printf(" %d\n",s[4][i]);
                   3239:   */
1.162     brouard  3240: 
1.226     brouard  3241:   ++countcallfunc;
1.162     brouard  3242: 
1.226     brouard  3243:   cov[1]=1.;
1.126     brouard  3244: 
1.226     brouard  3245:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3246:   ioffset=0;
1.226     brouard  3247:   if(mle==1){
                   3248:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3249:       /* Computes the values of the ncovmodel covariates of the model
                   3250:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3251:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3252:         to be observed in j being in i according to the model.
                   3253:       */
1.243     brouard  3254:       ioffset=2+nagesqr ;
1.233     brouard  3255:    /* Fixed */
1.234     brouard  3256:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3257:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3258:       }
1.226     brouard  3259:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3260:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3261:         has been calculated etc */
                   3262:       /* For an individual i, wav[i] gives the number of effective waves */
                   3263:       /* We compute the contribution to Likelihood of each effective transition
                   3264:         mw[mi][i] is real wave of the mi th effectve wave */
                   3265:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3266:         s2=s[mw[mi+1][i]][i];
                   3267:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3268:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3269:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3270:       */
                   3271:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3272:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3273:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3274:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3275:        }
                   3276:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3277:          for (j=1;j<=nlstate+ndeath;j++){
                   3278:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3279:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3280:          }
                   3281:        for(d=0; d<dh[mi][i]; d++){
                   3282:          newm=savm;
                   3283:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3284:          cov[2]=agexact;
                   3285:          if(nagesqr==1)
                   3286:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3287:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3288:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3289:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3290:          else
                   3291:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3292:          }
                   3293:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3294:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3295:          savm=oldm;
                   3296:          oldm=newm;
                   3297:        } /* end mult */
                   3298:        
                   3299:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3300:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3301:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3302:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3303:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3304:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3305:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3306:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3307:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3308:                                 * -stepm/2 to stepm/2 .
                   3309:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3310:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3311:                                 */
1.234     brouard  3312:        s1=s[mw[mi][i]][i];
                   3313:        s2=s[mw[mi+1][i]][i];
                   3314:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3315:        /* bias bh is positive if real duration
                   3316:         * is higher than the multiple of stepm and negative otherwise.
                   3317:         */
                   3318:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3319:        if( s2 > nlstate){ 
                   3320:          /* i.e. if s2 is a death state and if the date of death is known 
                   3321:             then the contribution to the likelihood is the probability to 
                   3322:             die between last step unit time and current  step unit time, 
                   3323:             which is also equal to probability to die before dh 
                   3324:             minus probability to die before dh-stepm . 
                   3325:             In version up to 0.92 likelihood was computed
                   3326:             as if date of death was unknown. Death was treated as any other
                   3327:             health state: the date of the interview describes the actual state
                   3328:             and not the date of a change in health state. The former idea was
                   3329:             to consider that at each interview the state was recorded
                   3330:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3331:             introduced the exact date of death then we should have modified
                   3332:             the contribution of an exact death to the likelihood. This new
                   3333:             contribution is smaller and very dependent of the step unit
                   3334:             stepm. It is no more the probability to die between last interview
                   3335:             and month of death but the probability to survive from last
                   3336:             interview up to one month before death multiplied by the
                   3337:             probability to die within a month. Thanks to Chris
                   3338:             Jackson for correcting this bug.  Former versions increased
                   3339:             mortality artificially. The bad side is that we add another loop
                   3340:             which slows down the processing. The difference can be up to 10%
                   3341:             lower mortality.
                   3342:          */
                   3343:          /* If, at the beginning of the maximization mostly, the
                   3344:             cumulative probability or probability to be dead is
                   3345:             constant (ie = 1) over time d, the difference is equal to
                   3346:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3347:             s1 at precedent wave, to be dead a month before current
                   3348:             wave is equal to probability, being at state s1 at
                   3349:             precedent wave, to be dead at mont of the current
                   3350:             wave. Then the observed probability (that this person died)
                   3351:             is null according to current estimated parameter. In fact,
                   3352:             it should be very low but not zero otherwise the log go to
                   3353:             infinity.
                   3354:          */
1.183     brouard  3355: /* #ifdef INFINITYORIGINAL */
                   3356: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3357: /* #else */
                   3358: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3359: /*         lli=log(mytinydouble); */
                   3360: /*       else */
                   3361: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3362: /* #endif */
1.226     brouard  3363:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3364:          
1.226     brouard  3365:        } else if  ( s2==-1 ) { /* alive */
                   3366:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3367:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3368:          /*survp += out[s1][j]; */
                   3369:          lli= log(survp);
                   3370:        }
                   3371:        else if  (s2==-4) { 
                   3372:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3373:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3374:          lli= log(survp); 
                   3375:        } 
                   3376:        else if  (s2==-5) { 
                   3377:          for (j=1,survp=0. ; j<=2; j++)  
                   3378:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3379:          lli= log(survp); 
                   3380:        } 
                   3381:        else{
                   3382:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3383:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3384:        } 
                   3385:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3386:        /*if(lli ==000.0)*/
                   3387:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3388:        ipmx +=1;
                   3389:        sw += weight[i];
                   3390:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3391:        /* if (lli < log(mytinydouble)){ */
                   3392:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3393:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3394:        /* } */
                   3395:       } /* end of wave */
                   3396:     } /* end of individual */
                   3397:   }  else if(mle==2){
                   3398:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3399:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3400:       for(mi=1; mi<= wav[i]-1; mi++){
                   3401:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3402:          for (j=1;j<=nlstate+ndeath;j++){
                   3403:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3404:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3405:          }
                   3406:        for(d=0; d<=dh[mi][i]; d++){
                   3407:          newm=savm;
                   3408:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3409:          cov[2]=agexact;
                   3410:          if(nagesqr==1)
                   3411:            cov[3]= agexact*agexact;
                   3412:          for (kk=1; kk<=cptcovage;kk++) {
                   3413:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3414:          }
                   3415:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3416:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3417:          savm=oldm;
                   3418:          oldm=newm;
                   3419:        } /* end mult */
                   3420:       
                   3421:        s1=s[mw[mi][i]][i];
                   3422:        s2=s[mw[mi+1][i]][i];
                   3423:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3424:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3425:        ipmx +=1;
                   3426:        sw += weight[i];
                   3427:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3428:       } /* end of wave */
                   3429:     } /* end of individual */
                   3430:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3431:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3432:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3433:       for(mi=1; mi<= wav[i]-1; mi++){
                   3434:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3435:          for (j=1;j<=nlstate+ndeath;j++){
                   3436:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3437:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3438:          }
                   3439:        for(d=0; d<dh[mi][i]; d++){
                   3440:          newm=savm;
                   3441:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3442:          cov[2]=agexact;
                   3443:          if(nagesqr==1)
                   3444:            cov[3]= agexact*agexact;
                   3445:          for (kk=1; kk<=cptcovage;kk++) {
                   3446:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3447:          }
                   3448:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3449:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3450:          savm=oldm;
                   3451:          oldm=newm;
                   3452:        } /* end mult */
                   3453:       
                   3454:        s1=s[mw[mi][i]][i];
                   3455:        s2=s[mw[mi+1][i]][i];
                   3456:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3457:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3458:        ipmx +=1;
                   3459:        sw += weight[i];
                   3460:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3461:       } /* end of wave */
                   3462:     } /* end of individual */
                   3463:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3464:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3465:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3466:       for(mi=1; mi<= wav[i]-1; mi++){
                   3467:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3468:          for (j=1;j<=nlstate+ndeath;j++){
                   3469:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3470:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3471:          }
                   3472:        for(d=0; d<dh[mi][i]; d++){
                   3473:          newm=savm;
                   3474:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3475:          cov[2]=agexact;
                   3476:          if(nagesqr==1)
                   3477:            cov[3]= agexact*agexact;
                   3478:          for (kk=1; kk<=cptcovage;kk++) {
                   3479:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3480:          }
1.126     brouard  3481:        
1.226     brouard  3482:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3483:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3484:          savm=oldm;
                   3485:          oldm=newm;
                   3486:        } /* end mult */
                   3487:       
                   3488:        s1=s[mw[mi][i]][i];
                   3489:        s2=s[mw[mi+1][i]][i];
                   3490:        if( s2 > nlstate){ 
                   3491:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3492:        } else if  ( s2==-1 ) { /* alive */
                   3493:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3494:            survp += out[s1][j];
                   3495:          lli= log(survp);
                   3496:        }else{
                   3497:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3498:        }
                   3499:        ipmx +=1;
                   3500:        sw += weight[i];
                   3501:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3502: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3503:       } /* end of wave */
                   3504:     } /* end of individual */
                   3505:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3506:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3507:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3508:       for(mi=1; mi<= wav[i]-1; mi++){
                   3509:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3510:          for (j=1;j<=nlstate+ndeath;j++){
                   3511:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3512:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3513:          }
                   3514:        for(d=0; d<dh[mi][i]; d++){
                   3515:          newm=savm;
                   3516:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3517:          cov[2]=agexact;
                   3518:          if(nagesqr==1)
                   3519:            cov[3]= agexact*agexact;
                   3520:          for (kk=1; kk<=cptcovage;kk++) {
                   3521:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3522:          }
1.126     brouard  3523:        
1.226     brouard  3524:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3525:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3526:          savm=oldm;
                   3527:          oldm=newm;
                   3528:        } /* end mult */
                   3529:       
                   3530:        s1=s[mw[mi][i]][i];
                   3531:        s2=s[mw[mi+1][i]][i];
                   3532:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3533:        ipmx +=1;
                   3534:        sw += weight[i];
                   3535:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3536:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3537:       } /* end of wave */
                   3538:     } /* end of individual */
                   3539:   } /* End of if */
                   3540:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3541:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3542:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3543:   return -l;
1.126     brouard  3544: }
                   3545: 
                   3546: /*************** log-likelihood *************/
                   3547: double funcone( double *x)
                   3548: {
1.228     brouard  3549:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3550:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3551:   int ioffset=0;
1.131     brouard  3552:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3553:   double **out;
                   3554:   double lli; /* Individual log likelihood */
                   3555:   double llt;
                   3556:   int s1, s2;
1.228     brouard  3557:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3558: 
1.126     brouard  3559:   double bbh, survp;
1.187     brouard  3560:   double agexact;
1.214     brouard  3561:   double agebegin, ageend;
1.126     brouard  3562:   /*extern weight */
                   3563:   /* We are differentiating ll according to initial status */
                   3564:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3565:   /*for(i=1;i<imx;i++) 
                   3566:     printf(" %d\n",s[4][i]);
                   3567:   */
                   3568:   cov[1]=1.;
                   3569: 
                   3570:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3571:   ioffset=0;
                   3572:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3573:     /* ioffset=2+nagesqr+cptcovage; */
                   3574:     ioffset=2+nagesqr;
1.232     brouard  3575:     /* Fixed */
1.224     brouard  3576:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3577:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3578:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3579:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3580: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3581: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3582: /*    cov[2+6]=covar[2][i]; V2  */
                   3583: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3584: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3585: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3586: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3587: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3588: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3589:     }
1.232     brouard  3590:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3591:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3592:     /* } */
1.231     brouard  3593:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3594:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3595:     /* } */
1.225     brouard  3596:     
1.233     brouard  3597: 
                   3598:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3599:     /* Wave varying (but not age varying) */
                   3600:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3601:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3602:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3603:       }
1.232     brouard  3604:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3605:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3606:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3607:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3608:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3609:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3610:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3611:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3612:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3613:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3614:       /* } */
1.126     brouard  3615:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3616:        for (j=1;j<=nlstate+ndeath;j++){
                   3617:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3618:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3619:        }
1.214     brouard  3620:       
                   3621:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3622:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3623:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3624:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3625:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3626:          and mw[mi+1][i]. dh depends on stepm.*/
                   3627:        newm=savm;
1.247     brouard  3628:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3629:        cov[2]=agexact;
                   3630:        if(nagesqr==1)
                   3631:          cov[3]= agexact*agexact;
                   3632:        for (kk=1; kk<=cptcovage;kk++) {
                   3633:          if(!FixedV[Tvar[Tage[kk]]])
                   3634:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3635:          else
                   3636:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3637:        }
                   3638:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3639:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3640:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3641:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3642:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3643:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3644:        savm=oldm;
                   3645:        oldm=newm;
1.126     brouard  3646:       } /* end mult */
                   3647:       
                   3648:       s1=s[mw[mi][i]][i];
                   3649:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3650:       /* if(s2==-1){ */
                   3651:       /*       printf(" s1=%d, s2=%d i=%d \n", s1, s2, i); */
                   3652:       /*       /\* exit(1); *\/ */
                   3653:       /* } */
1.126     brouard  3654:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3655:       /* bias is positive if real duration
                   3656:        * is higher than the multiple of stepm and negative otherwise.
                   3657:        */
                   3658:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3659:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3660:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3661:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3662:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3663:        lli= log(survp);
1.126     brouard  3664:       }else if (mle==1){
1.242     brouard  3665:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3666:       } else if(mle==2){
1.242     brouard  3667:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3668:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3669:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3670:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3671:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3672:       } else{  /* mle=0 back to 1 */
1.242     brouard  3673:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3674:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3675:       } /* End of if */
                   3676:       ipmx +=1;
                   3677:       sw += weight[i];
                   3678:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3679:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3680:       if(globpr){
1.246     brouard  3681:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3682:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3683:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
                   3684:                2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
                   3685:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3686:          llt +=ll[k]*gipmx/gsw;
                   3687:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3688:        }
                   3689:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3690:       }
1.232     brouard  3691:        } /* end of wave */
                   3692: } /* end of individual */
                   3693: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3694: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3695: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3696: if(globpr==0){ /* First time we count the contributions and weights */
                   3697:        gipmx=ipmx;
                   3698:        gsw=sw;
                   3699: }
                   3700: return -l;
1.126     brouard  3701: }
                   3702: 
                   3703: 
                   3704: /*************** function likelione ***********/
                   3705: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3706: {
                   3707:   /* This routine should help understanding what is done with 
                   3708:      the selection of individuals/waves and
                   3709:      to check the exact contribution to the likelihood.
                   3710:      Plotting could be done.
                   3711:    */
                   3712:   int k;
                   3713: 
                   3714:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3715:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3716:     strcat(fileresilk,fileresu);
1.126     brouard  3717:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3718:       printf("Problem with resultfile: %s\n", fileresilk);
                   3719:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3720:     }
1.214     brouard  3721:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3722:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3723:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3724:     for(k=1; k<=nlstate; k++) 
                   3725:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3726:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3727:   }
                   3728: 
                   3729:   *fretone=(*funcone)(p);
                   3730:   if(*globpri !=0){
                   3731:     fclose(ficresilk);
1.205     brouard  3732:     if (mle ==0)
                   3733:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3734:     else if(mle >=1)
                   3735:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3736:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3737:     
1.208     brouard  3738:       
                   3739:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3740:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3741: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3742:     }
1.207     brouard  3743:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3744: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3745:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3746: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3747:     fflush(fichtm);
1.205     brouard  3748:   }
1.126     brouard  3749:   return;
                   3750: }
                   3751: 
                   3752: 
                   3753: /*********** Maximum Likelihood Estimation ***************/
                   3754: 
                   3755: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3756: {
1.165     brouard  3757:   int i,j, iter=0;
1.126     brouard  3758:   double **xi;
                   3759:   double fret;
                   3760:   double fretone; /* Only one call to likelihood */
                   3761:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3762: 
                   3763: #ifdef NLOPT
                   3764:   int creturn;
                   3765:   nlopt_opt opt;
                   3766:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3767:   double *lb;
                   3768:   double minf; /* the minimum objective value, upon return */
                   3769:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3770:   myfunc_data dinst, *d = &dinst;
                   3771: #endif
                   3772: 
                   3773: 
1.126     brouard  3774:   xi=matrix(1,npar,1,npar);
                   3775:   for (i=1;i<=npar;i++)
                   3776:     for (j=1;j<=npar;j++)
                   3777:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3778:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3779:   strcpy(filerespow,"POW_"); 
1.126     brouard  3780:   strcat(filerespow,fileres);
                   3781:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3782:     printf("Problem with resultfile: %s\n", filerespow);
                   3783:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3784:   }
                   3785:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3786:   for (i=1;i<=nlstate;i++)
                   3787:     for(j=1;j<=nlstate+ndeath;j++)
                   3788:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3789:   fprintf(ficrespow,"\n");
1.162     brouard  3790: #ifdef POWELL
1.126     brouard  3791:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3792: #endif
1.126     brouard  3793: 
1.162     brouard  3794: #ifdef NLOPT
                   3795: #ifdef NEWUOA
                   3796:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3797: #else
                   3798:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3799: #endif
                   3800:   lb=vector(0,npar-1);
                   3801:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3802:   nlopt_set_lower_bounds(opt, lb);
                   3803:   nlopt_set_initial_step1(opt, 0.1);
                   3804:   
                   3805:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3806:   d->function = func;
                   3807:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3808:   nlopt_set_min_objective(opt, myfunc, d);
                   3809:   nlopt_set_xtol_rel(opt, ftol);
                   3810:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3811:     printf("nlopt failed! %d\n",creturn); 
                   3812:   }
                   3813:   else {
                   3814:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3815:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3816:     iter=1; /* not equal */
                   3817:   }
                   3818:   nlopt_destroy(opt);
                   3819: #endif
1.126     brouard  3820:   free_matrix(xi,1,npar,1,npar);
                   3821:   fclose(ficrespow);
1.203     brouard  3822:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3823:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3824:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3825: 
                   3826: }
                   3827: 
                   3828: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3829: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3830: {
                   3831:   double  **a,**y,*x,pd;
1.203     brouard  3832:   /* double **hess; */
1.164     brouard  3833:   int i, j;
1.126     brouard  3834:   int *indx;
                   3835: 
                   3836:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3837:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3838:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3839:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3840:   double gompertz(double p[]);
1.203     brouard  3841:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3842: 
                   3843:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3844:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3845:   for (i=1;i<=npar;i++){
1.203     brouard  3846:     printf("%d-",i);fflush(stdout);
                   3847:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3848:    
                   3849:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3850:     
                   3851:     /*  printf(" %f ",p[i]);
                   3852:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3853:   }
                   3854:   
                   3855:   for (i=1;i<=npar;i++) {
                   3856:     for (j=1;j<=npar;j++)  {
                   3857:       if (j>i) { 
1.203     brouard  3858:        printf(".%d-%d",i,j);fflush(stdout);
                   3859:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3860:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3861:        
                   3862:        hess[j][i]=hess[i][j];    
                   3863:        /*printf(" %lf ",hess[i][j]);*/
                   3864:       }
                   3865:     }
                   3866:   }
                   3867:   printf("\n");
                   3868:   fprintf(ficlog,"\n");
                   3869: 
                   3870:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3871:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3872:   
                   3873:   a=matrix(1,npar,1,npar);
                   3874:   y=matrix(1,npar,1,npar);
                   3875:   x=vector(1,npar);
                   3876:   indx=ivector(1,npar);
                   3877:   for (i=1;i<=npar;i++)
                   3878:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3879:   ludcmp(a,npar,indx,&pd);
                   3880: 
                   3881:   for (j=1;j<=npar;j++) {
                   3882:     for (i=1;i<=npar;i++) x[i]=0;
                   3883:     x[j]=1;
                   3884:     lubksb(a,npar,indx,x);
                   3885:     for (i=1;i<=npar;i++){ 
                   3886:       matcov[i][j]=x[i];
                   3887:     }
                   3888:   }
                   3889: 
                   3890:   printf("\n#Hessian matrix#\n");
                   3891:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   3892:   for (i=1;i<=npar;i++) { 
                   3893:     for (j=1;j<=npar;j++) { 
1.203     brouard  3894:       printf("%.6e ",hess[i][j]);
                   3895:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  3896:     }
                   3897:     printf("\n");
                   3898:     fprintf(ficlog,"\n");
                   3899:   }
                   3900: 
1.203     brouard  3901:   /* printf("\n#Covariance matrix#\n"); */
                   3902:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   3903:   /* for (i=1;i<=npar;i++) {  */
                   3904:   /*   for (j=1;j<=npar;j++) {  */
                   3905:   /*     printf("%.6e ",matcov[i][j]); */
                   3906:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   3907:   /*   } */
                   3908:   /*   printf("\n"); */
                   3909:   /*   fprintf(ficlog,"\n"); */
                   3910:   /* } */
                   3911: 
1.126     brouard  3912:   /* Recompute Inverse */
1.203     brouard  3913:   /* for (i=1;i<=npar;i++) */
                   3914:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   3915:   /* ludcmp(a,npar,indx,&pd); */
                   3916: 
                   3917:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   3918: 
                   3919:   /* for (j=1;j<=npar;j++) { */
                   3920:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   3921:   /*   x[j]=1; */
                   3922:   /*   lubksb(a,npar,indx,x); */
                   3923:   /*   for (i=1;i<=npar;i++){  */
                   3924:   /*     y[i][j]=x[i]; */
                   3925:   /*     printf("%.3e ",y[i][j]); */
                   3926:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   3927:   /*   } */
                   3928:   /*   printf("\n"); */
                   3929:   /*   fprintf(ficlog,"\n"); */
                   3930:   /* } */
                   3931: 
                   3932:   /* Verifying the inverse matrix */
                   3933: #ifdef DEBUGHESS
                   3934:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  3935: 
1.203     brouard  3936:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   3937:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  3938: 
                   3939:   for (j=1;j<=npar;j++) {
                   3940:     for (i=1;i<=npar;i++){ 
1.203     brouard  3941:       printf("%.2f ",y[i][j]);
                   3942:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  3943:     }
                   3944:     printf("\n");
                   3945:     fprintf(ficlog,"\n");
                   3946:   }
1.203     brouard  3947: #endif
1.126     brouard  3948: 
                   3949:   free_matrix(a,1,npar,1,npar);
                   3950:   free_matrix(y,1,npar,1,npar);
                   3951:   free_vector(x,1,npar);
                   3952:   free_ivector(indx,1,npar);
1.203     brouard  3953:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  3954: 
                   3955: 
                   3956: }
                   3957: 
                   3958: /*************** hessian matrix ****************/
                   3959: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  3960: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  3961:   int i;
                   3962:   int l=1, lmax=20;
1.203     brouard  3963:   double k1,k2, res, fx;
1.132     brouard  3964:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  3965:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   3966:   int k=0,kmax=10;
                   3967:   double l1;
                   3968: 
                   3969:   fx=func(x);
                   3970:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  3971:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  3972:     l1=pow(10,l);
                   3973:     delts=delt;
                   3974:     for(k=1 ; k <kmax; k=k+1){
                   3975:       delt = delta*(l1*k);
                   3976:       p2[theta]=x[theta] +delt;
1.145     brouard  3977:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  3978:       p2[theta]=x[theta]-delt;
                   3979:       k2=func(p2)-fx;
                   3980:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  3981:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  3982:       
1.203     brouard  3983: #ifdef DEBUGHESSII
1.126     brouard  3984:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3985:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3986: #endif
                   3987:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   3988:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   3989:        k=kmax;
                   3990:       }
                   3991:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  3992:        k=kmax; l=lmax*10;
1.126     brouard  3993:       }
                   3994:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   3995:        delts=delt;
                   3996:       }
1.203     brouard  3997:     } /* End loop k */
1.126     brouard  3998:   }
                   3999:   delti[theta]=delts;
                   4000:   return res; 
                   4001:   
                   4002: }
                   4003: 
1.203     brouard  4004: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4005: {
                   4006:   int i;
1.164     brouard  4007:   int l=1, lmax=20;
1.126     brouard  4008:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4009:   double p2[MAXPARM+1];
1.203     brouard  4010:   int k, kmax=1;
                   4011:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4012: 
                   4013:   int firstime=0;
1.203     brouard  4014:   
1.126     brouard  4015:   fx=func(x);
1.203     brouard  4016:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4017:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4018:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4019:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4020:     k1=func(p2)-fx;
                   4021:   
1.203     brouard  4022:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4023:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4024:     k2=func(p2)-fx;
                   4025:   
1.203     brouard  4026:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4027:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4028:     k3=func(p2)-fx;
                   4029:   
1.203     brouard  4030:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4031:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4032:     k4=func(p2)-fx;
1.203     brouard  4033:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4034:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4035:       firstime=1;
1.203     brouard  4036:       kmax=kmax+10;
1.208     brouard  4037:     }
                   4038:     if(kmax >=10 || firstime ==1){
1.246     brouard  4039:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4040:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4041:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4042:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4043:     }
                   4044: #ifdef DEBUGHESSIJ
                   4045:     v1=hess[thetai][thetai];
                   4046:     v2=hess[thetaj][thetaj];
                   4047:     cv12=res;
                   4048:     /* Computing eigen value of Hessian matrix */
                   4049:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4050:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4051:     if ((lc2 <0) || (lc1 <0) ){
                   4052:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4053:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4054:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4055:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4056:     }
1.126     brouard  4057: #endif
                   4058:   }
                   4059:   return res;
                   4060: }
                   4061: 
1.203     brouard  4062:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4063: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4064: /* { */
                   4065: /*   int i; */
                   4066: /*   int l=1, lmax=20; */
                   4067: /*   double k1,k2,k3,k4,res,fx; */
                   4068: /*   double p2[MAXPARM+1]; */
                   4069: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4070: /*   int k=0,kmax=10; */
                   4071: /*   double l1; */
                   4072:   
                   4073: /*   fx=func(x); */
                   4074: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4075: /*     l1=pow(10,l); */
                   4076: /*     delts=delt; */
                   4077: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4078: /*       delt = delti*(l1*k); */
                   4079: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4080: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4081: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4082: /*       k1=func(p2)-fx; */
                   4083:       
                   4084: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4085: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4086: /*       k2=func(p2)-fx; */
                   4087:       
                   4088: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4089: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4090: /*       k3=func(p2)-fx; */
                   4091:       
                   4092: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4093: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4094: /*       k4=func(p2)-fx; */
                   4095: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4096: /* #ifdef DEBUGHESSIJ */
                   4097: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4098: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4099: /* #endif */
                   4100: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4101: /*     k=kmax; */
                   4102: /*       } */
                   4103: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4104: /*     k=kmax; l=lmax*10; */
                   4105: /*       } */
                   4106: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4107: /*     delts=delt; */
                   4108: /*       } */
                   4109: /*     } /\* End loop k *\/ */
                   4110: /*   } */
                   4111: /*   delti[theta]=delts; */
                   4112: /*   return res;  */
                   4113: /* } */
                   4114: 
                   4115: 
1.126     brouard  4116: /************** Inverse of matrix **************/
                   4117: void ludcmp(double **a, int n, int *indx, double *d) 
                   4118: { 
                   4119:   int i,imax,j,k; 
                   4120:   double big,dum,sum,temp; 
                   4121:   double *vv; 
                   4122:  
                   4123:   vv=vector(1,n); 
                   4124:   *d=1.0; 
                   4125:   for (i=1;i<=n;i++) { 
                   4126:     big=0.0; 
                   4127:     for (j=1;j<=n;j++) 
                   4128:       if ((temp=fabs(a[i][j])) > big) big=temp; 
                   4129:     if (big == 0.0) nrerror("Singular matrix in routine ludcmp"); 
                   4130:     vv[i]=1.0/big; 
                   4131:   } 
                   4132:   for (j=1;j<=n;j++) { 
                   4133:     for (i=1;i<j;i++) { 
                   4134:       sum=a[i][j]; 
                   4135:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4136:       a[i][j]=sum; 
                   4137:     } 
                   4138:     big=0.0; 
                   4139:     for (i=j;i<=n;i++) { 
                   4140:       sum=a[i][j]; 
                   4141:       for (k=1;k<j;k++) 
                   4142:        sum -= a[i][k]*a[k][j]; 
                   4143:       a[i][j]=sum; 
                   4144:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4145:        big=dum; 
                   4146:        imax=i; 
                   4147:       } 
                   4148:     } 
                   4149:     if (j != imax) { 
                   4150:       for (k=1;k<=n;k++) { 
                   4151:        dum=a[imax][k]; 
                   4152:        a[imax][k]=a[j][k]; 
                   4153:        a[j][k]=dum; 
                   4154:       } 
                   4155:       *d = -(*d); 
                   4156:       vv[imax]=vv[j]; 
                   4157:     } 
                   4158:     indx[j]=imax; 
                   4159:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4160:     if (j != n) { 
                   4161:       dum=1.0/(a[j][j]); 
                   4162:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4163:     } 
                   4164:   } 
                   4165:   free_vector(vv,1,n);  /* Doesn't work */
                   4166: ;
                   4167: } 
                   4168: 
                   4169: void lubksb(double **a, int n, int *indx, double b[]) 
                   4170: { 
                   4171:   int i,ii=0,ip,j; 
                   4172:   double sum; 
                   4173:  
                   4174:   for (i=1;i<=n;i++) { 
                   4175:     ip=indx[i]; 
                   4176:     sum=b[ip]; 
                   4177:     b[ip]=b[i]; 
                   4178:     if (ii) 
                   4179:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4180:     else if (sum) ii=i; 
                   4181:     b[i]=sum; 
                   4182:   } 
                   4183:   for (i=n;i>=1;i--) { 
                   4184:     sum=b[i]; 
                   4185:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4186:     b[i]=sum/a[i][i]; 
                   4187:   } 
                   4188: } 
                   4189: 
                   4190: void pstamp(FILE *fichier)
                   4191: {
1.196     brouard  4192:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4193: }
                   4194: 
1.253     brouard  4195: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4196: 
                   4197:   /* y=a+bx regression */
                   4198:   double   sumx = 0.0;                        /* sum of x                      */
                   4199:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4200:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4201:   double   sumy = 0.0;                        /* sum of y                      */
                   4202:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4203:   double   sume2; /* sum of square or residuals */
                   4204:   double yhat;
                   4205:   
                   4206:   double denom=0;
                   4207:   int i;
                   4208:   int ne=*no;
                   4209:   
                   4210:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4211:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4212:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4213:       continue;
                   4214:     }
                   4215:     ne=ne+1;
                   4216:     sumx  += x[i];       
                   4217:     sumx2 += x[i]*x[i];  
                   4218:     sumxy += x[i] * y[i];
                   4219:     sumy  += y[i];      
                   4220:     sumy2 += y[i]*y[i]; 
                   4221:     denom = (ne * sumx2 - sumx*sumx);
                   4222:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4223:   } 
                   4224:   
                   4225:   denom = (ne * sumx2 - sumx*sumx);
                   4226:   if (denom == 0) {
                   4227:     // vertical, slope m is infinity
                   4228:     *b = INFINITY;
                   4229:     *a = 0;
                   4230:     if (r) *r = 0;
                   4231:     return 1;
                   4232:   }
                   4233:   
                   4234:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   4235:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   4236:   if (r!=NULL) {
                   4237:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   4238:       sqrt((sumx2 - sumx*sumx/ne) *
                   4239:           (sumy2 - sumy*sumy/ne));
                   4240:   }
                   4241:   *no=ne;
                   4242:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4243:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4244:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4245:       continue;
                   4246:     }
                   4247:     ne=ne+1;
                   4248:     yhat = y[i] - *a -*b* x[i];
                   4249:     sume2  += yhat * yhat ;       
                   4250:     
                   4251:     denom = (ne * sumx2 - sumx*sumx);
                   4252:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4253:   } 
                   4254:   *sb = sqrt(sume2/(ne-2)/(sumx2 - sumx * sumx /ne));
                   4255:   *sa= *sb * sqrt(sumx2/ne);
                   4256:   
                   4257:   return 0; 
                   4258: }
                   4259: 
1.126     brouard  4260: /************ Frequencies ********************/
1.251     brouard  4261: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4262:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4263:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4264: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4265:   
1.253     brouard  4266:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0;
1.226     brouard  4267:   int iind=0, iage=0;
                   4268:   int mi; /* Effective wave */
                   4269:   int first;
                   4270:   double ***freq; /* Frequencies */
1.253     brouard  4271:   double *x, *y, a,b,r, sa, sb; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4272:   int no;
1.226     brouard  4273:   double *meanq;
                   4274:   double **meanqt;
                   4275:   double *pp, **prop, *posprop, *pospropt;
                   4276:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4277:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4278:   double agebegin, ageend;
                   4279:     
                   4280:   pp=vector(1,nlstate);
1.251     brouard  4281:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4282:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4283:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4284:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4285:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4286:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4287:   strcpy(fileresp,"P_");
                   4288:   strcat(fileresp,fileresu);
                   4289:   /*strcat(fileresphtm,fileresu);*/
                   4290:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4291:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4292:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4293:     exit(0);
                   4294:   }
1.240     brouard  4295:   
1.226     brouard  4296:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4297:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4298:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4299:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4300:     fflush(ficlog);
                   4301:     exit(70); 
                   4302:   }
                   4303:   else{
                   4304:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4305: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4306: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4307:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4308:   }
1.237     brouard  4309:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4310:   
1.226     brouard  4311:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4312:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4313:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4314:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4315:     fflush(ficlog);
                   4316:     exit(70); 
1.240     brouard  4317:   } else{
1.226     brouard  4318:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4319: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4320: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4321:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4322:   }
1.240     brouard  4323:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4324:   
1.253     brouard  4325:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4326:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4327:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4328:   j1=0;
1.126     brouard  4329:   
1.227     brouard  4330:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4331:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4332:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4333:   
                   4334:   
1.226     brouard  4335:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4336:      reference=low_education V1=0,V2=0
                   4337:      med_educ                V1=1 V2=0, 
                   4338:      high_educ               V1=0 V2=1
                   4339:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4340:   */
1.249     brouard  4341:   dateintsum=0;
                   4342:   k2cpt=0;
                   4343: 
1.253     brouard  4344:   if(cptcoveff == 0 )
                   4345:     nl=1;  /* Constant model only */
                   4346:   else
                   4347:     nl=2;
                   4348:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4349:     if(nj==1)
                   4350:       j=0;  /* First pass for the constant */
                   4351:     else
                   4352:       j=cptcoveff; /* Other passes for the covariate values */
1.251     brouard  4353:     first=1;
                   4354:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on covariates combination in order of model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
                   4355:       posproptt=0.;
                   4356:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4357:        scanf("%d", i);*/
                   4358:       for (i=-5; i<=nlstate+ndeath; i++)  
                   4359:        for (jk=-5; jk<=nlstate+ndeath; jk++)  
                   4360:          for(m=iagemin; m <= iagemax+3; m++)
                   4361:            freq[i][jk][m]=0;
                   4362:       
                   4363:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4364:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4365:          prop[i][m]=0;
                   4366:        posprop[i]=0;
                   4367:        pospropt[i]=0;
                   4368:       }
                   4369:       /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4370:       /*   meanq[z1]+=0.; */
                   4371:       /*   for(m=1;m<=lastpass;m++){ */
                   4372:       /*       meanqt[m][z1]=0.; */
                   4373:       /*   } */
                   4374:       /* } */
                   4375:       
                   4376:       /* dateintsum=0; */
                   4377:       /* k2cpt=0; */
                   4378:       
                   4379:       /* For that combination of covariate j1, we count and print the frequencies in one pass */
                   4380:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4381:        bool=1;
                   4382:        if(j !=0){
                   4383:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4384:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4385:              /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4386:              /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4387:              /* } */
                   4388:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4389:                /* if(Tvaraff[z1] ==-20){ */
                   4390:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4391:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4392:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4393:                /* }else  */
                   4394:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
                   4395:                  /* Tests if this individual iind responded to combination j1 (V4=1 V3=0) */
                   4396:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4397:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4398:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4399:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4400:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4401:                } /* Onlyf fixed */
                   4402:              } /* end z1 */
                   4403:            } /* cptcovn > 0 */
                   4404:          } /* end any */
                   4405:        }/* end j==0 */
                   4406:        if (bool==1){ /* We selected an individual iind satisfying combination j1 or all fixed */
                   4407:          /* for(m=firstpass; m<=lastpass; m++){ */
                   4408:          for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4409:            m=mw[mi][iind];
                   4410:            if(j!=0){
                   4411:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4412:                for (z1=1; z1<=cptcoveff; z1++) {
                   4413:                  if( Fixed[Tmodelind[z1]]==1){
                   4414:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4415:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4416:                                                                                      value is -1, we don't select. It differs from the 
                   4417:                                                                                      constant and age model which counts them. */
                   4418:                      bool=0; /* not selected */
                   4419:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4420:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4421:                      bool=0;
                   4422:                    }
                   4423:                  }
                   4424:                }
                   4425:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4426:            } /* end j==0 */
                   4427:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4428:            if(bool==1){
                   4429:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4430:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4431:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4432:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4433:              if(m >=firstpass && m <=lastpass){
                   4434:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4435:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4436:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4437:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4438:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4439:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4440:                if (m<lastpass) {
                   4441:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4442:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4443:                  if(s[m][iind]==-1)
                   4444:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4445:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4446:                  /* if((int)agev[m][iind] == 55) */
                   4447:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4448:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4449:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4450:                }
1.251     brouard  4451:              } /* end if between passes */  
                   4452:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4453:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4454:                k2cpt++;
                   4455:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4456:              }
1.251     brouard  4457:            }else{
                   4458:              bool=1;
                   4459:            }/* end bool 2 */
                   4460:          } /* end m */
                   4461:        } /* end bool */
                   4462:       } /* end iind = 1 to imx */
                   4463:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4464:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4465:       
                   4466:       
                   4467:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
                   4468:       pstamp(ficresp);
                   4469:       if  (cptcoveff>0 && j!=0){
                   4470:        printf( "\n#********** Variable "); 
                   4471:        fprintf(ficresp, "\n#********** Variable "); 
                   4472:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4473:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4474:        fprintf(ficlog, "\n#********** Variable "); 
                   4475:        for (z1=1; z1<=cptcoveff; z1++){
                   4476:          if(!FixedV[Tvaraff[z1]]){
                   4477:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4478:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4479:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4480:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4481:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4482:          }else{
1.251     brouard  4483:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4484:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4485:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4486:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4487:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4488:          }
                   4489:        }
                   4490:        printf( "**********\n#");
                   4491:        fprintf(ficresp, "**********\n#");
                   4492:        fprintf(ficresphtm, "**********</h3>\n");
                   4493:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4494:        fprintf(ficlog, "**********\n");
                   4495:       }
                   4496:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
                   4497:       for(i=1; i<=nlstate;i++) {
                   4498:        fprintf(ficresp, " Age Prev(%d)  N(%d)  N  ",i,i);
                   4499:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4500:       }
                   4501:       fprintf(ficresp, "\n");
                   4502:       fprintf(ficresphtm, "\n");
                   4503:       
                   4504:       /* Header of frequency table by age */
                   4505:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4506:       fprintf(ficresphtmfr,"<th>Age</th> ");
                   4507:       for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4508:        for(m=-1; m <=nlstate+ndeath; m++){
                   4509:          if(jk!=0 && m!=0)
                   4510:            fprintf(ficresphtmfr,"<th>%d%d</th> ",jk,m);
1.240     brouard  4511:        }
1.226     brouard  4512:       }
1.251     brouard  4513:       fprintf(ficresphtmfr, "\n");
                   4514:     
                   4515:       /* For each age */
                   4516:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4517:        fprintf(ficresphtm,"<tr>");
                   4518:        if(iage==iagemax+1){
                   4519:          fprintf(ficlog,"1");
                   4520:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4521:        }else if(iage==iagemax+2){
                   4522:          fprintf(ficlog,"0");
                   4523:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4524:        }else if(iage==iagemax+3){
                   4525:          fprintf(ficlog,"Total");
                   4526:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4527:        }else{
1.240     brouard  4528:          if(first==1){
1.251     brouard  4529:            first=0;
                   4530:            printf("See log file for details...\n");
                   4531:          }
                   4532:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4533:          fprintf(ficlog,"Age %d", iage);
                   4534:        }
                   4535:        for(jk=1; jk <=nlstate ; jk++){
                   4536:          for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
                   4537:            pp[jk] += freq[jk][m][iage]; 
                   4538:        }
                   4539:        for(jk=1; jk <=nlstate ; jk++){
                   4540:          for(m=-1, pos=0; m <=0 ; m++)
                   4541:            pos += freq[jk][m][iage];
                   4542:          if(pp[jk]>=1.e-10){
                   4543:            if(first==1){
                   4544:              printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4545:            }
                   4546:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4547:          }else{
                   4548:            if(first==1)
                   4549:              printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
                   4550:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
1.240     brouard  4551:          }
                   4552:        }
                   4553:       
1.251     brouard  4554:        for(jk=1; jk <=nlstate ; jk++){ 
                   4555:          /* posprop[jk]=0; */
                   4556:          for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4557:            pp[jk] += freq[jk][m][iage];
                   4558:        }       /* pp[jk] is the total number of transitions starting from state jk and any ending status until this age */
                   4559:       
                   4560:        for(jk=1,pos=0, pospropta=0.; jk <=nlstate ; jk++){
                   4561:          pos += pp[jk]; /* pos is the total number of transitions until this age */
                   4562:          posprop[jk] += prop[jk][iage]; /* prop is the number of transitions from a live state
                   4563:                                            from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4564:          pospropta += prop[jk][iage]; /* prop is the number of transitions from a live state
1.240     brouard  4565:                                          from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4566:        }
1.251     brouard  4567:        for(jk=1; jk <=nlstate ; jk++){
1.240     brouard  4568:          if(pos>=1.e-5){
1.251     brouard  4569:            if(first==1)
                   4570:              printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4571:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4572:          }else{
                   4573:            if(first==1)
                   4574:              printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4575:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4576:          }
                   4577:          if( iage <= iagemax){
                   4578:            if(pos>=1.e-5){
                   4579:              fprintf(ficresp," %d %.5f %.0f %.0f",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4580:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4581:              /*probs[iage][jk][j1]= pp[jk]/pos;*/
                   4582:              /*printf("\niage=%d jk=%d j1=%d %.5f %.0f %.0f %f",iage,jk,j1,pp[jk]/pos, pp[jk],pos,probs[iage][jk][j1]);*/
                   4583:            }
                   4584:            else{
                   4585:              fprintf(ficresp," %d NaNq %.0f %.0f",iage,prop[jk][iage],pospropta);
                   4586:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[jk][iage],pospropta);
                   4587:            }
1.240     brouard  4588:          }
1.251     brouard  4589:          pospropt[jk] +=posprop[jk];
                   4590:        } /* end loop jk */
                   4591:        /* pospropt=0.; */
                   4592:        for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4593:          for(m=-1; m <=nlstate+ndeath; m++){
                   4594:            if(freq[jk][m][iage] !=0 ) { /* minimizing output */
                   4595:              if(first==1){
                   4596:                printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4597:              }
1.253     brouard  4598:              /* printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]); */
1.251     brouard  4599:              fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4600:            }
                   4601:            if(jk!=0 && m!=0)
                   4602:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[jk][m][iage]);
1.240     brouard  4603:          }
1.251     brouard  4604:        } /* end loop jk */
                   4605:        posproptt=0.; 
                   4606:        for(jk=1; jk <=nlstate; jk++){
                   4607:          posproptt += pospropt[jk];
                   4608:        }
                   4609:        fprintf(ficresphtmfr,"</tr>\n ");
                   4610:        if(iage <= iagemax){
                   4611:          fprintf(ficresp,"\n");
                   4612:          fprintf(ficresphtm,"</tr>\n");
1.240     brouard  4613:        }
1.251     brouard  4614:        if(first==1)
                   4615:          printf("Others in log...\n");
                   4616:        fprintf(ficlog,"\n");
                   4617:       } /* end loop age iage */
                   4618:       fprintf(ficresphtm,"<tr><th>Tot</th>");
                   4619:       for(jk=1; jk <=nlstate ; jk++){
                   4620:        if(posproptt < 1.e-5){
                   4621:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[jk],posproptt); 
                   4622:        }else{
                   4623:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[jk]/posproptt,pospropt[jk],posproptt);  
1.240     brouard  4624:        }
1.226     brouard  4625:       }
1.251     brouard  4626:       fprintf(ficresphtm,"</tr>\n");
                   4627:       fprintf(ficresphtm,"</table>\n");
                   4628:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4629:       if(posproptt < 1.e-5){
1.251     brouard  4630:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4631:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4632:        fprintf(ficres,"\n  This combination (%d) is not valid and no result will be produced\n\n",j1);
                   4633:        invalidvarcomb[j1]=1;
1.226     brouard  4634:       }else{
1.251     brouard  4635:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4636:        invalidvarcomb[j1]=0;
1.226     brouard  4637:       }
1.251     brouard  4638:       fprintf(ficresphtmfr,"</table>\n");
                   4639:       fprintf(ficlog,"\n");
                   4640:       if(j!=0){
                   4641:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
                   4642:        for(i=1,jk=1; i <=nlstate; i++){
                   4643:          for(k=1; k <=(nlstate+ndeath); k++){
                   4644:            if (k != i) {
                   4645:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting jk */
1.253     brouard  4646:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4647:                  if(j1==1){ /* All dummy covariates to zero */
                   4648:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4649:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4650:                    printf("%d%d ",i,k);
                   4651:                    fprintf(ficlog,"%d%d ",i,k);
                   4652:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4653:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4654:                    pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4655:                  }
1.253     brouard  4656:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4657:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4658:                    x[iage]= (double)iage;
                   4659:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
                   4660:                    /* printf("i=%d, k=%d, jk=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,jk,j1,jj, iage, y[iage]); */
                   4661:                  }
                   4662:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
                   4663:                  pstart[jk]=b;
                   4664:                  pstart[jk-1]=a;
1.252     brouard  4665:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4666:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4667:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.251     brouard  4668:                  pstart[jk]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4669:                  printf("%d%d ",i,k);
                   4670:                  fprintf(ficlog,"%d%d ",i,k);
1.251     brouard  4671:                  printf("jk=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",jk,i,k,jk,p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
                   4672:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4673:                  ;
                   4674:                }
                   4675:                /* printf("%12.7f )", param[i][jj][k]); */
                   4676:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
                   4677:                jk++; 
                   4678:              } /* end jj */
                   4679:            } /* end k!= i */
                   4680:          } /* end k */
                   4681:        } /* end i, jk */
                   4682:       } /* end j !=0 */
                   4683:     } /* end selected combination of covariate j1 */
                   4684:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4685:       printf("#Freqsummary: Starting values for the constants:\n");
                   4686:       fprintf(ficlog,"\n");
                   4687:       for(i=1,jk=1; i <=nlstate; i++){
                   4688:        for(k=1; k <=(nlstate+ndeath); k++){
                   4689:          if (k != i) {
                   4690:            printf("%d%d ",i,k);
                   4691:            fprintf(ficlog,"%d%d ",i,k);
                   4692:            for(jj=1; jj <=ncovmodel; jj++){
1.253     brouard  4693:              pstart[jk]=p[jk]; /* Setting pstart to p values by default */
                   4694:              if(jj==1){ /* Age has to be done */
                   4695:                pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4696:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4697:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4698:              }
                   4699:              /* printf("%12.7f )", param[i][jj][k]); */
                   4700:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
                   4701:              jk++; 
1.250     brouard  4702:            }
1.251     brouard  4703:            printf("\n");
                   4704:            fprintf(ficlog,"\n");
1.250     brouard  4705:          }
                   4706:        }
                   4707:       }
1.251     brouard  4708:       printf("#Freqsummary\n");
                   4709:       fprintf(ficlog,"\n");
                   4710:       for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4711:        for(m=-1; m <=nlstate+ndeath; m++){
                   4712:          /* param[i]|j][k]= freq[jk][m][iagemax+3] */
1.250     brouard  4713:          printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
                   4714:          fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
1.251     brouard  4715:          /* if(freq[jk][m][iage] !=0 ) { /\* minimizing output *\/ */
                   4716:          /*   printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
                   4717:          /*   fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
                   4718:          /* } */
                   4719:        }
                   4720:       } /* end loop jk */
                   4721:       
                   4722:       printf("\n");
                   4723:       fprintf(ficlog,"\n");
                   4724:     } /* end j=0 */
1.249     brouard  4725:   } /* end j */
1.252     brouard  4726: 
1.253     brouard  4727:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4728:     for(i=1, jk=1; i <=nlstate; i++){
                   4729:       for(j=1; j <=nlstate+ndeath; j++){
                   4730:        if(j!=i){
                   4731:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4732:          printf("%1d%1d",i,j);
                   4733:          fprintf(ficparo,"%1d%1d",i,j);
                   4734:          for(k=1; k<=ncovmodel;k++){
                   4735:            /*    printf(" %lf",param[i][j][k]); */
                   4736:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4737:            p[jk]=pstart[jk];
                   4738:            printf(" %f ",pstart[jk]);
                   4739:            fprintf(ficparo," %f ",pstart[jk]);
                   4740:            jk++;
                   4741:          }
                   4742:          printf("\n");
                   4743:          fprintf(ficparo,"\n");
                   4744:        }
                   4745:       }
                   4746:     }
                   4747:   } /* end mle=-2 */
1.226     brouard  4748:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4749:   
1.226     brouard  4750:   fclose(ficresp);
                   4751:   fclose(ficresphtm);
                   4752:   fclose(ficresphtmfr);
                   4753:   free_vector(meanq,1,nqfveff);
                   4754:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4755:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4756:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4757:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4758:   free_vector(pospropt,1,nlstate);
                   4759:   free_vector(posprop,1,nlstate);
1.251     brouard  4760:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4761:   free_vector(pp,1,nlstate);
                   4762:   /* End of freqsummary */
                   4763: }
1.126     brouard  4764: 
                   4765: /************ Prevalence ********************/
1.227     brouard  4766: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4767: {  
                   4768:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4769:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4770:      We still use firstpass and lastpass as another selection.
                   4771:   */
1.126     brouard  4772:  
1.227     brouard  4773:   int i, m, jk, j1, bool, z1,j, iv;
                   4774:   int mi; /* Effective wave */
                   4775:   int iage;
                   4776:   double agebegin, ageend;
                   4777: 
                   4778:   double **prop;
                   4779:   double posprop; 
                   4780:   double  y2; /* in fractional years */
                   4781:   int iagemin, iagemax;
                   4782:   int first; /** to stop verbosity which is redirected to log file */
                   4783: 
                   4784:   iagemin= (int) agemin;
                   4785:   iagemax= (int) agemax;
                   4786:   /*pp=vector(1,nlstate);*/
1.251     brouard  4787:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  4788:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4789:   j1=0;
1.222     brouard  4790:   
1.227     brouard  4791:   /*j=cptcoveff;*/
                   4792:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4793:   
1.227     brouard  4794:   first=1;
                   4795:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4796:     for (i=1; i<=nlstate; i++)  
1.251     brouard  4797:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  4798:        prop[i][iage]=0.0;
                   4799:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4800:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4801:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4802:     
                   4803:     for (i=1; i<=imx; i++) { /* Each individual */
                   4804:       bool=1;
                   4805:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4806:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4807:        m=mw[mi][i];
                   4808:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4809:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4810:        for (z1=1; z1<=cptcoveff; z1++){
                   4811:          if( Fixed[Tmodelind[z1]]==1){
                   4812:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4813:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4814:              bool=0;
                   4815:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4816:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4817:              bool=0;
                   4818:            }
                   4819:        }
                   4820:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4821:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4822:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4823:          if(m >=firstpass && m <=lastpass){
                   4824:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4825:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4826:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   4827:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  4828:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  4829:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   4830:                exit(1);
                   4831:              }
                   4832:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   4833:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   4834:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   4835:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   4836:              } /* end valid statuses */ 
                   4837:            } /* end selection of dates */
                   4838:          } /* end selection of waves */
                   4839:        } /* end bool */
                   4840:       } /* end wave */
                   4841:     } /* end individual */
                   4842:     for(i=iagemin; i <= iagemax+3; i++){  
                   4843:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   4844:        posprop += prop[jk][i]; 
                   4845:       } 
                   4846:       
                   4847:       for(jk=1; jk <=nlstate ; jk++){      
                   4848:        if( i <=  iagemax){ 
                   4849:          if(posprop>=1.e-5){ 
                   4850:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   4851:          } else{
                   4852:            if(first==1){
                   4853:              first=0;
                   4854:              printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,j1,probs[i][jk][j1]);
                   4855:            }
                   4856:          }
                   4857:        } 
                   4858:       }/* end jk */ 
                   4859:     }/* end i */ 
1.222     brouard  4860:      /*} *//* end i1 */
1.227     brouard  4861:   } /* end j1 */
1.222     brouard  4862:   
1.227     brouard  4863:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   4864:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  4865:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  4866: }  /* End of prevalence */
1.126     brouard  4867: 
                   4868: /************* Waves Concatenation ***************/
                   4869: 
                   4870: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   4871: {
                   4872:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   4873:      Death is a valid wave (if date is known).
                   4874:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   4875:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4876:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  4877:   */
1.126     brouard  4878: 
1.224     brouard  4879:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  4880:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   4881:      double sum=0., jmean=0.;*/
1.224     brouard  4882:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  4883:   int j, k=0,jk, ju, jl;
                   4884:   double sum=0.;
                   4885:   first=0;
1.214     brouard  4886:   firstwo=0;
1.217     brouard  4887:   firsthree=0;
1.218     brouard  4888:   firstfour=0;
1.164     brouard  4889:   jmin=100000;
1.126     brouard  4890:   jmax=-1;
                   4891:   jmean=0.;
1.224     brouard  4892: 
                   4893: /* Treating live states */
1.214     brouard  4894:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  4895:     mi=0;  /* First valid wave */
1.227     brouard  4896:     mli=0; /* Last valid wave */
1.126     brouard  4897:     m=firstpass;
1.214     brouard  4898:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  4899:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   4900:        mli=m-1;/* mw[++mi][i]=m-1; */
                   4901:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   4902:        mw[++mi][i]=m;
                   4903:        mli=m;
1.224     brouard  4904:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   4905:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  4906:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  4907:       }
1.227     brouard  4908:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  4909: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  4910:        break;
1.224     brouard  4911: #else
1.227     brouard  4912:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   4913:          if(firsthree == 0){
                   4914:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4915:            firsthree=1;
                   4916:          }
                   4917:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4918:          mw[++mi][i]=m;
                   4919:          mli=m;
                   4920:        }
                   4921:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   4922:          nbwarn++;
                   4923:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   4924:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4925:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4926:          }
                   4927:          break;
                   4928:        }
                   4929:        break;
1.224     brouard  4930: #endif
1.227     brouard  4931:       }/* End m >= lastpass */
1.126     brouard  4932:     }/* end while */
1.224     brouard  4933: 
1.227     brouard  4934:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  4935:     /* After last pass */
1.224     brouard  4936: /* Treating death states */
1.214     brouard  4937:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  4938:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   4939:       /* } */
1.126     brouard  4940:       mi++;    /* Death is another wave */
                   4941:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  4942:       /* Only death is a correct wave */
1.126     brouard  4943:       mw[mi][i]=m;
1.224     brouard  4944:     }
                   4945: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.227     brouard  4946:     else if ((int) andc[i] != 9999) { /* Status is negative. A death occured after lastpass, we can't take it into account because of potential bias */
1.216     brouard  4947:       /* m++; */
                   4948:       /* mi++; */
                   4949:       /* s[m][i]=nlstate+1;  /\* We are setting the status to the last of non live state *\/ */
                   4950:       /* mw[mi][i]=m; */
1.218     brouard  4951:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  4952:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   4953:          nbwarn++;
                   4954:          if(firstfiv==0){
                   4955:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4956:            firstfiv=1;
                   4957:          }else{
                   4958:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4959:          }
                   4960:        }else{ /* Death occured afer last wave potential bias */
                   4961:          nberr++;
                   4962:          if(firstwo==0){
                   4963:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4964:            firstwo=1;
                   4965:          }
                   4966:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4967:        }
1.218     brouard  4968:       }else{ /* end date of interview is known */
1.227     brouard  4969:        /* death is known but not confirmed by death status at any wave */
                   4970:        if(firstfour==0){
                   4971:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4972:          firstfour=1;
                   4973:        }
                   4974:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  4975:       }
1.224     brouard  4976:     } /* end if date of death is known */
                   4977: #endif
                   4978:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   4979:     /* wav[i]=mw[mi][i]; */
1.126     brouard  4980:     if(mi==0){
                   4981:       nbwarn++;
                   4982:       if(first==0){
1.227     brouard  4983:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   4984:        first=1;
1.126     brouard  4985:       }
                   4986:       if(first==1){
1.227     brouard  4987:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  4988:       }
                   4989:     } /* end mi==0 */
                   4990:   } /* End individuals */
1.214     brouard  4991:   /* wav and mw are no more changed */
1.223     brouard  4992:        
1.214     brouard  4993:   
1.126     brouard  4994:   for(i=1; i<=imx; i++){
                   4995:     for(mi=1; mi<wav[i];mi++){
                   4996:       if (stepm <=0)
1.227     brouard  4997:        dh[mi][i]=1;
1.126     brouard  4998:       else{
1.227     brouard  4999:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death */
                   5000:          if (agedc[i] < 2*AGESUP) {
                   5001:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5002:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5003:            else if(j<0){
                   5004:              nberr++;
                   5005:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5006:              j=1; /* Temporary Dangerous patch */
                   5007:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5008:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5009:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5010:            }
                   5011:            k=k+1;
                   5012:            if (j >= jmax){
                   5013:              jmax=j;
                   5014:              ijmax=i;
                   5015:            }
                   5016:            if (j <= jmin){
                   5017:              jmin=j;
                   5018:              ijmin=i;
                   5019:            }
                   5020:            sum=sum+j;
                   5021:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5022:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5023:          }
                   5024:        }
                   5025:        else{
                   5026:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5027: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5028:                                        
1.227     brouard  5029:          k=k+1;
                   5030:          if (j >= jmax) {
                   5031:            jmax=j;
                   5032:            ijmax=i;
                   5033:          }
                   5034:          else if (j <= jmin){
                   5035:            jmin=j;
                   5036:            ijmin=i;
                   5037:          }
                   5038:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5039:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5040:          if(j<0){
                   5041:            nberr++;
                   5042:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5043:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5044:          }
                   5045:          sum=sum+j;
                   5046:        }
                   5047:        jk= j/stepm;
                   5048:        jl= j -jk*stepm;
                   5049:        ju= j -(jk+1)*stepm;
                   5050:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5051:          if(jl==0){
                   5052:            dh[mi][i]=jk;
                   5053:            bh[mi][i]=0;
                   5054:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5055:                  * to avoid the price of an extra matrix product in likelihood */
                   5056:            dh[mi][i]=jk+1;
                   5057:            bh[mi][i]=ju;
                   5058:          }
                   5059:        }else{
                   5060:          if(jl <= -ju){
                   5061:            dh[mi][i]=jk;
                   5062:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5063:                                 * is higher than the multiple of stepm and negative otherwise.
                   5064:                                 */
                   5065:          }
                   5066:          else{
                   5067:            dh[mi][i]=jk+1;
                   5068:            bh[mi][i]=ju;
                   5069:          }
                   5070:          if(dh[mi][i]==0){
                   5071:            dh[mi][i]=1; /* At least one step */
                   5072:            bh[mi][i]=ju; /* At least one step */
                   5073:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5074:          }
                   5075:        } /* end if mle */
1.126     brouard  5076:       }
                   5077:     } /* end wave */
                   5078:   }
                   5079:   jmean=sum/k;
                   5080:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5081:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5082: }
1.126     brouard  5083: 
                   5084: /*********** Tricode ****************************/
1.220     brouard  5085:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5086:  {
                   5087:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5088:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5089:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5090:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5091:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5092:     */
1.130     brouard  5093: 
1.242     brouard  5094:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5095:    int modmaxcovj=0; /* Modality max of covariates j */
                   5096:    int cptcode=0; /* Modality max of covariates j */
                   5097:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5098: 
                   5099: 
1.242     brouard  5100:    /* cptcoveff=0;  */
                   5101:    /* *cptcov=0; */
1.126     brouard  5102:  
1.242     brouard  5103:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  5104: 
1.242     brouard  5105:    /* Loop on covariates without age and products and no quantitative variable */
                   5106:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5107:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5108:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5109:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5110:        switch(Fixed[k]) {
                   5111:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5112:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5113:           ij=(int)(covar[Tvar[k]][i]);
                   5114:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5115:            * If product of Vn*Vm, still boolean *:
                   5116:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5117:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5118:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5119:              modality of the nth covariate of individual i. */
                   5120:           if (ij > modmaxcovj)
                   5121:             modmaxcovj=ij; 
                   5122:           else if (ij < modmincovj) 
                   5123:             modmincovj=ij; 
                   5124:           if ((ij < -1) && (ij > NCOVMAX)){
                   5125:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5126:             exit(1);
                   5127:           }else
                   5128:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5129:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5130:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5131:           /* getting the maximum value of the modality of the covariate
                   5132:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5133:              female ies 1, then modmaxcovj=1.
                   5134:           */
                   5135:         } /* end for loop on individuals i */
                   5136:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5137:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5138:         cptcode=modmaxcovj;
                   5139:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5140:         /*for (i=0; i<=cptcode; i++) {*/
                   5141:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5142:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5143:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5144:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5145:             if( j != -1){
                   5146:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5147:                                  covariate for which somebody answered excluding 
                   5148:                                  undefined. Usually 2: 0 and 1. */
                   5149:             }
                   5150:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5151:                                     covariate for which somebody answered including 
                   5152:                                     undefined. Usually 3: -1, 0 and 1. */
                   5153:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5154:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5155:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5156:                        
1.242     brouard  5157:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5158:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5159:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5160:         /* modmincovj=3; modmaxcovj = 7; */
                   5161:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5162:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5163:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5164:         /* nbcode[Tvar[j]][ij]=k; */
                   5165:         /* nbcode[Tvar[j]][1]=0; */
                   5166:         /* nbcode[Tvar[j]][2]=1; */
                   5167:         /* nbcode[Tvar[j]][3]=2; */
                   5168:         /* To be continued (not working yet). */
                   5169:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5170:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5171:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5172:             break;
                   5173:           }
                   5174:           ij++;
                   5175:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5176:           cptcode = ij; /* New max modality for covar j */
                   5177:         } /* end of loop on modality i=-1 to 1 or more */
                   5178:         break;
                   5179:        case 1: /* Testing on varying covariate, could be simple and
                   5180:                * should look at waves or product of fixed *
                   5181:                * varying. No time to test -1, assuming 0 and 1 only */
                   5182:         ij=0;
                   5183:         for(i=0; i<=1;i++){
                   5184:           nbcode[Tvar[k]][++ij]=i;
                   5185:         }
                   5186:         break;
                   5187:        default:
                   5188:         break;
                   5189:        } /* end switch */
                   5190:      } /* end dummy test */
                   5191:     
                   5192:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5193:      /*        /\*recode from 0 *\/ */
                   5194:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5195:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5196:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5197:      /*        } */
                   5198:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5199:      /*        if (ij > ncodemax[j]) { */
                   5200:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5201:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5202:      /*          break; */
                   5203:      /*        } */
                   5204:      /*   }  /\* end of loop on modality k *\/ */
                   5205:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5206:   
                   5207:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5208:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5209:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5210:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5211:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5212:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5213:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5214:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5215:   
                   5216:    ij=0;
                   5217:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5218:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5219:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5220:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5221:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5222:        /* If product not in single variable we don't print results */
                   5223:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5224:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5225:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5226:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5227:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5228:        if(Fixed[k]!=0)
                   5229:         anyvaryingduminmodel=1;
                   5230:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5231:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5232:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5233:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5234:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5235:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5236:      } 
                   5237:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5238:    /* ij--; */
                   5239:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5240:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5241:                * because they can be excluded from the model and real
                   5242:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5243:    for(j=ij+1; j<= cptcovt; j++){
                   5244:      Tvaraff[j]=0;
                   5245:      Tmodelind[j]=0;
                   5246:    }
                   5247:    for(j=ntveff+1; j<= cptcovt; j++){
                   5248:      TmodelInvind[j]=0;
                   5249:    }
                   5250:    /* To be sorted */
                   5251:    ;
                   5252:  }
1.126     brouard  5253: 
1.145     brouard  5254: 
1.126     brouard  5255: /*********** Health Expectancies ****************/
                   5256: 
1.235     brouard  5257:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5258: 
                   5259: {
                   5260:   /* Health expectancies, no variances */
1.164     brouard  5261:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5262:   int nhstepma, nstepma; /* Decreasing with age */
                   5263:   double age, agelim, hf;
                   5264:   double ***p3mat;
                   5265:   double eip;
                   5266: 
1.238     brouard  5267:   /* pstamp(ficreseij); */
1.126     brouard  5268:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5269:   fprintf(ficreseij,"# Age");
                   5270:   for(i=1; i<=nlstate;i++){
                   5271:     for(j=1; j<=nlstate;j++){
                   5272:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5273:     }
                   5274:     fprintf(ficreseij," e%1d. ",i);
                   5275:   }
                   5276:   fprintf(ficreseij,"\n");
                   5277: 
                   5278:   
                   5279:   if(estepm < stepm){
                   5280:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5281:   }
                   5282:   else  hstepm=estepm;   
                   5283:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5284:    * This is mainly to measure the difference between two models: for example
                   5285:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5286:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5287:    * progression in between and thus overestimating or underestimating according
                   5288:    * to the curvature of the survival function. If, for the same date, we 
                   5289:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5290:    * to compare the new estimate of Life expectancy with the same linear 
                   5291:    * hypothesis. A more precise result, taking into account a more precise
                   5292:    * curvature will be obtained if estepm is as small as stepm. */
                   5293: 
                   5294:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5295:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5296:      nhstepm is the number of hstepm from age to agelim 
                   5297:      nstepm is the number of stepm from age to agelin. 
                   5298:      Look at hpijx to understand the reason of that which relies in memory size
                   5299:      and note for a fixed period like estepm months */
                   5300:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5301:      survival function given by stepm (the optimization length). Unfortunately it
                   5302:      means that if the survival funtion is printed only each two years of age and if
                   5303:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5304:      results. So we changed our mind and took the option of the best precision.
                   5305:   */
                   5306:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5307: 
                   5308:   agelim=AGESUP;
                   5309:   /* If stepm=6 months */
                   5310:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5311:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5312:     
                   5313: /* nhstepm age range expressed in number of stepm */
                   5314:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5315:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5316:   /* if (stepm >= YEARM) hstepm=1;*/
                   5317:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5318:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5319: 
                   5320:   for (age=bage; age<=fage; age ++){ 
                   5321:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5322:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5323:     /* if (stepm >= YEARM) hstepm=1;*/
                   5324:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5325: 
                   5326:     /* If stepm=6 months */
                   5327:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5328:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5329:     
1.235     brouard  5330:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5331:     
                   5332:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5333:     
                   5334:     printf("%d|",(int)age);fflush(stdout);
                   5335:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5336:     
                   5337:     /* Computing expectancies */
                   5338:     for(i=1; i<=nlstate;i++)
                   5339:       for(j=1; j<=nlstate;j++)
                   5340:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5341:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5342:          
                   5343:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5344: 
                   5345:        }
                   5346: 
                   5347:     fprintf(ficreseij,"%3.0f",age );
                   5348:     for(i=1; i<=nlstate;i++){
                   5349:       eip=0;
                   5350:       for(j=1; j<=nlstate;j++){
                   5351:        eip +=eij[i][j][(int)age];
                   5352:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5353:       }
                   5354:       fprintf(ficreseij,"%9.4f", eip );
                   5355:     }
                   5356:     fprintf(ficreseij,"\n");
                   5357:     
                   5358:   }
                   5359:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5360:   printf("\n");
                   5361:   fprintf(ficlog,"\n");
                   5362:   
                   5363: }
                   5364: 
1.235     brouard  5365:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5366: 
                   5367: {
                   5368:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5369:      to initial status i, ei. .
1.126     brouard  5370:   */
                   5371:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5372:   int nhstepma, nstepma; /* Decreasing with age */
                   5373:   double age, agelim, hf;
                   5374:   double ***p3matp, ***p3matm, ***varhe;
                   5375:   double **dnewm,**doldm;
                   5376:   double *xp, *xm;
                   5377:   double **gp, **gm;
                   5378:   double ***gradg, ***trgradg;
                   5379:   int theta;
                   5380: 
                   5381:   double eip, vip;
                   5382: 
                   5383:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5384:   xp=vector(1,npar);
                   5385:   xm=vector(1,npar);
                   5386:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5387:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5388:   
                   5389:   pstamp(ficresstdeij);
                   5390:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5391:   fprintf(ficresstdeij,"# Age");
                   5392:   for(i=1; i<=nlstate;i++){
                   5393:     for(j=1; j<=nlstate;j++)
                   5394:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5395:     fprintf(ficresstdeij," e%1d. ",i);
                   5396:   }
                   5397:   fprintf(ficresstdeij,"\n");
                   5398: 
                   5399:   pstamp(ficrescveij);
                   5400:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5401:   fprintf(ficrescveij,"# Age");
                   5402:   for(i=1; i<=nlstate;i++)
                   5403:     for(j=1; j<=nlstate;j++){
                   5404:       cptj= (j-1)*nlstate+i;
                   5405:       for(i2=1; i2<=nlstate;i2++)
                   5406:        for(j2=1; j2<=nlstate;j2++){
                   5407:          cptj2= (j2-1)*nlstate+i2;
                   5408:          if(cptj2 <= cptj)
                   5409:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5410:        }
                   5411:     }
                   5412:   fprintf(ficrescveij,"\n");
                   5413:   
                   5414:   if(estepm < stepm){
                   5415:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5416:   }
                   5417:   else  hstepm=estepm;   
                   5418:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5419:    * This is mainly to measure the difference between two models: for example
                   5420:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5421:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5422:    * progression in between and thus overestimating or underestimating according
                   5423:    * to the curvature of the survival function. If, for the same date, we 
                   5424:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5425:    * to compare the new estimate of Life expectancy with the same linear 
                   5426:    * hypothesis. A more precise result, taking into account a more precise
                   5427:    * curvature will be obtained if estepm is as small as stepm. */
                   5428: 
                   5429:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5430:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5431:      nhstepm is the number of hstepm from age to agelim 
                   5432:      nstepm is the number of stepm from age to agelin. 
                   5433:      Look at hpijx to understand the reason of that which relies in memory size
                   5434:      and note for a fixed period like estepm months */
                   5435:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5436:      survival function given by stepm (the optimization length). Unfortunately it
                   5437:      means that if the survival funtion is printed only each two years of age and if
                   5438:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5439:      results. So we changed our mind and took the option of the best precision.
                   5440:   */
                   5441:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5442: 
                   5443:   /* If stepm=6 months */
                   5444:   /* nhstepm age range expressed in number of stepm */
                   5445:   agelim=AGESUP;
                   5446:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5447:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5448:   /* if (stepm >= YEARM) hstepm=1;*/
                   5449:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5450:   
                   5451:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5452:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5453:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5454:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5455:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5456:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5457: 
                   5458:   for (age=bage; age<=fage; age ++){ 
                   5459:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5460:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5461:     /* if (stepm >= YEARM) hstepm=1;*/
                   5462:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5463:                
1.126     brouard  5464:     /* If stepm=6 months */
                   5465:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5466:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5467:     
                   5468:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5469:                
1.126     brouard  5470:     /* Computing  Variances of health expectancies */
                   5471:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5472:        decrease memory allocation */
                   5473:     for(theta=1; theta <=npar; theta++){
                   5474:       for(i=1; i<=npar; i++){ 
1.222     brouard  5475:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5476:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5477:       }
1.235     brouard  5478:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5479:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5480:                        
1.126     brouard  5481:       for(j=1; j<= nlstate; j++){
1.222     brouard  5482:        for(i=1; i<=nlstate; i++){
                   5483:          for(h=0; h<=nhstepm-1; h++){
                   5484:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5485:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5486:          }
                   5487:        }
1.126     brouard  5488:       }
1.218     brouard  5489:                        
1.126     brouard  5490:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5491:        for(h=0; h<=nhstepm-1; h++){
                   5492:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5493:        }
1.126     brouard  5494:     }/* End theta */
                   5495:     
                   5496:     
                   5497:     for(h=0; h<=nhstepm-1; h++)
                   5498:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5499:        for(theta=1; theta <=npar; theta++)
                   5500:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5501:     
1.218     brouard  5502:                
1.222     brouard  5503:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5504:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5505:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5506:                
1.222     brouard  5507:     printf("%d|",(int)age);fflush(stdout);
                   5508:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5509:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5510:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5511:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5512:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5513:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5514:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5515:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5516:       }
                   5517:     }
1.218     brouard  5518:                
1.126     brouard  5519:     /* Computing expectancies */
1.235     brouard  5520:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5521:     for(i=1; i<=nlstate;i++)
                   5522:       for(j=1; j<=nlstate;j++)
1.222     brouard  5523:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5524:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5525:                                        
1.222     brouard  5526:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5527:                                        
1.222     brouard  5528:        }
1.218     brouard  5529:                
1.126     brouard  5530:     fprintf(ficresstdeij,"%3.0f",age );
                   5531:     for(i=1; i<=nlstate;i++){
                   5532:       eip=0.;
                   5533:       vip=0.;
                   5534:       for(j=1; j<=nlstate;j++){
1.222     brouard  5535:        eip += eij[i][j][(int)age];
                   5536:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5537:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5538:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5539:       }
                   5540:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5541:     }
                   5542:     fprintf(ficresstdeij,"\n");
1.218     brouard  5543:                
1.126     brouard  5544:     fprintf(ficrescveij,"%3.0f",age );
                   5545:     for(i=1; i<=nlstate;i++)
                   5546:       for(j=1; j<=nlstate;j++){
1.222     brouard  5547:        cptj= (j-1)*nlstate+i;
                   5548:        for(i2=1; i2<=nlstate;i2++)
                   5549:          for(j2=1; j2<=nlstate;j2++){
                   5550:            cptj2= (j2-1)*nlstate+i2;
                   5551:            if(cptj2 <= cptj)
                   5552:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5553:          }
1.126     brouard  5554:       }
                   5555:     fprintf(ficrescveij,"\n");
1.218     brouard  5556:                
1.126     brouard  5557:   }
                   5558:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5559:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5560:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5561:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5562:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5563:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5564:   printf("\n");
                   5565:   fprintf(ficlog,"\n");
1.218     brouard  5566:        
1.126     brouard  5567:   free_vector(xm,1,npar);
                   5568:   free_vector(xp,1,npar);
                   5569:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5570:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5571:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5572: }
1.218     brouard  5573:  
1.126     brouard  5574: /************ Variance ******************/
1.235     brouard  5575:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5576:  {
                   5577:    /* Variance of health expectancies */
                   5578:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5579:    /* double **newm;*/
                   5580:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5581:   
                   5582:    /* int movingaverage(); */
                   5583:    double **dnewm,**doldm;
                   5584:    double **dnewmp,**doldmp;
                   5585:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5586:    int k;
                   5587:    double *xp;
                   5588:    double **gp, **gm;  /* for var eij */
                   5589:    double ***gradg, ***trgradg; /*for var eij */
                   5590:    double **gradgp, **trgradgp; /* for var p point j */
                   5591:    double *gpp, *gmp; /* for var p point j */
                   5592:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5593:    double ***p3mat;
                   5594:    double age,agelim, hf;
                   5595:    /* double ***mobaverage; */
                   5596:    int theta;
                   5597:    char digit[4];
                   5598:    char digitp[25];
                   5599: 
                   5600:    char fileresprobmorprev[FILENAMELENGTH];
                   5601: 
                   5602:    if(popbased==1){
                   5603:      if(mobilav!=0)
                   5604:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5605:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5606:    }
                   5607:    else 
                   5608:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5609: 
1.218     brouard  5610:    /* if (mobilav!=0) { */
                   5611:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5612:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5613:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5614:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5615:    /*   } */
                   5616:    /* } */
                   5617: 
                   5618:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5619:    sprintf(digit,"%-d",ij);
                   5620:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5621:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5622:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5623:    strcat(fileresprobmorprev,fileresu);
                   5624:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5625:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5626:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5627:    }
                   5628:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5629:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5630:    pstamp(ficresprobmorprev);
                   5631:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5632:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5633:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5634:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5635:    }
                   5636:    for(j=1;j<=cptcoveff;j++) 
                   5637:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5638:    fprintf(ficresprobmorprev,"\n");
                   5639: 
1.218     brouard  5640:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5641:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5642:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5643:      for(i=1; i<=nlstate;i++)
                   5644:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5645:    }  
                   5646:    fprintf(ficresprobmorprev,"\n");
                   5647:   
                   5648:    fprintf(ficgp,"\n# Routine varevsij");
                   5649:    fprintf(ficgp,"\nunset title \n");
                   5650:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5651:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5652:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5653:    /*   } */
                   5654:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5655:    pstamp(ficresvij);
                   5656:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5657:    if(popbased==1)
                   5658:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5659:    else
                   5660:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5661:    fprintf(ficresvij,"# Age");
                   5662:    for(i=1; i<=nlstate;i++)
                   5663:      for(j=1; j<=nlstate;j++)
                   5664:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5665:    fprintf(ficresvij,"\n");
                   5666: 
                   5667:    xp=vector(1,npar);
                   5668:    dnewm=matrix(1,nlstate,1,npar);
                   5669:    doldm=matrix(1,nlstate,1,nlstate);
                   5670:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5671:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5672: 
                   5673:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5674:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5675:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5676:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5677:   
1.218     brouard  5678:    if(estepm < stepm){
                   5679:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5680:    }
                   5681:    else  hstepm=estepm;   
                   5682:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5683:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5684:       nhstepm is the number of hstepm from age to agelim 
                   5685:       nstepm is the number of stepm from age to agelim. 
                   5686:       Look at function hpijx to understand why because of memory size limitations, 
                   5687:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5688:       survival function given by stepm (the optimization length). Unfortunately it
                   5689:       means that if the survival funtion is printed every two years of age and if
                   5690:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5691:       results. So we changed our mind and took the option of the best precision.
                   5692:    */
                   5693:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5694:    agelim = AGESUP;
                   5695:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5696:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5697:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5698:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5699:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5700:      gp=matrix(0,nhstepm,1,nlstate);
                   5701:      gm=matrix(0,nhstepm,1,nlstate);
                   5702:                
                   5703:                
                   5704:      for(theta=1; theta <=npar; theta++){
                   5705:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5706:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5707:        }
                   5708:                        
1.242     brouard  5709:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5710:                        
                   5711:        if (popbased==1) {
                   5712:         if(mobilav ==0){
                   5713:           for(i=1; i<=nlstate;i++)
                   5714:             prlim[i][i]=probs[(int)age][i][ij];
                   5715:         }else{ /* mobilav */ 
                   5716:           for(i=1; i<=nlstate;i++)
                   5717:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5718:         }
                   5719:        }
                   5720:                        
1.235     brouard  5721:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5722:        for(j=1; j<= nlstate; j++){
                   5723:         for(h=0; h<=nhstepm; h++){
                   5724:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5725:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5726:         }
                   5727:        }
                   5728:        /* Next for computing probability of death (h=1 means
                   5729:          computed over hstepm matrices product = hstepm*stepm months) 
                   5730:          as a weighted average of prlim.
                   5731:        */
                   5732:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5733:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5734:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5735:        }    
                   5736:        /* end probability of death */
                   5737:                        
                   5738:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5739:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5740:                        
1.242     brouard  5741:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5742:                        
                   5743:        if (popbased==1) {
                   5744:         if(mobilav ==0){
                   5745:           for(i=1; i<=nlstate;i++)
                   5746:             prlim[i][i]=probs[(int)age][i][ij];
                   5747:         }else{ /* mobilav */ 
                   5748:           for(i=1; i<=nlstate;i++)
                   5749:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5750:         }
                   5751:        }
                   5752:                        
1.235     brouard  5753:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5754:                        
                   5755:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5756:         for(h=0; h<=nhstepm; h++){
                   5757:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5758:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5759:         }
                   5760:        }
                   5761:        /* This for computing probability of death (h=1 means
                   5762:          computed over hstepm matrices product = hstepm*stepm months) 
                   5763:          as a weighted average of prlim.
                   5764:        */
                   5765:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5766:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5767:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5768:        }    
                   5769:        /* end probability of death */
                   5770:                        
                   5771:        for(j=1; j<= nlstate; j++) /* vareij */
                   5772:         for(h=0; h<=nhstepm; h++){
                   5773:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5774:         }
                   5775:                        
                   5776:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5777:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5778:        }
                   5779:                        
                   5780:      } /* End theta */
                   5781:                
                   5782:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5783:                
                   5784:      for(h=0; h<=nhstepm; h++) /* veij */
                   5785:        for(j=1; j<=nlstate;j++)
                   5786:         for(theta=1; theta <=npar; theta++)
                   5787:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5788:                
                   5789:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5790:        for(theta=1; theta <=npar; theta++)
                   5791:         trgradgp[j][theta]=gradgp[theta][j];
                   5792:                
                   5793:                
                   5794:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5795:      for(i=1;i<=nlstate;i++)
                   5796:        for(j=1;j<=nlstate;j++)
                   5797:         vareij[i][j][(int)age] =0.;
                   5798:                
                   5799:      for(h=0;h<=nhstepm;h++){
                   5800:        for(k=0;k<=nhstepm;k++){
                   5801:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5802:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5803:         for(i=1;i<=nlstate;i++)
                   5804:           for(j=1;j<=nlstate;j++)
                   5805:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5806:        }
                   5807:      }
                   5808:                
                   5809:      /* pptj */
                   5810:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5811:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5812:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5813:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5814:         varppt[j][i]=doldmp[j][i];
                   5815:      /* end ppptj */
                   5816:      /*  x centered again */
                   5817:                
1.242     brouard  5818:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5819:                
                   5820:      if (popbased==1) {
                   5821:        if(mobilav ==0){
                   5822:         for(i=1; i<=nlstate;i++)
                   5823:           prlim[i][i]=probs[(int)age][i][ij];
                   5824:        }else{ /* mobilav */ 
                   5825:         for(i=1; i<=nlstate;i++)
                   5826:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   5827:        }
                   5828:      }
                   5829:                
                   5830:      /* This for computing probability of death (h=1 means
                   5831:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   5832:        as a weighted average of prlim.
                   5833:      */
1.235     brouard  5834:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  5835:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5836:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   5837:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   5838:      }    
                   5839:      /* end probability of death */
                   5840:                
                   5841:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   5842:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5843:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   5844:        for(i=1; i<=nlstate;i++){
                   5845:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   5846:        }
                   5847:      } 
                   5848:      fprintf(ficresprobmorprev,"\n");
                   5849:                
                   5850:      fprintf(ficresvij,"%.0f ",age );
                   5851:      for(i=1; i<=nlstate;i++)
                   5852:        for(j=1; j<=nlstate;j++){
                   5853:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   5854:        }
                   5855:      fprintf(ficresvij,"\n");
                   5856:      free_matrix(gp,0,nhstepm,1,nlstate);
                   5857:      free_matrix(gm,0,nhstepm,1,nlstate);
                   5858:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   5859:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   5860:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5861:    } /* End age */
                   5862:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   5863:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   5864:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   5865:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   5866:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   5867:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   5868:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   5869:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   5870:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5871:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   5872:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5873:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5874:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   5875:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   5876:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   5877:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   5878:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5879:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  5880:     */
1.218     brouard  5881:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   5882:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  5883: 
1.218     brouard  5884:    free_vector(xp,1,npar);
                   5885:    free_matrix(doldm,1,nlstate,1,nlstate);
                   5886:    free_matrix(dnewm,1,nlstate,1,npar);
                   5887:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5888:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   5889:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5890:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5891:    fclose(ficresprobmorprev);
                   5892:    fflush(ficgp);
                   5893:    fflush(fichtm); 
                   5894:  }  /* end varevsij */
1.126     brouard  5895: 
                   5896: /************ Variance of prevlim ******************/
1.235     brouard  5897:  void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  5898: {
1.205     brouard  5899:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  5900:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  5901: 
1.126     brouard  5902:   double **dnewm,**doldm;
                   5903:   int i, j, nhstepm, hstepm;
                   5904:   double *xp;
                   5905:   double *gp, *gm;
                   5906:   double **gradg, **trgradg;
1.208     brouard  5907:   double **mgm, **mgp;
1.126     brouard  5908:   double age,agelim;
                   5909:   int theta;
                   5910:   
                   5911:   pstamp(ficresvpl);
                   5912:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  5913:   fprintf(ficresvpl,"# Age ");
                   5914:   if(nresult >=1)
                   5915:     fprintf(ficresvpl," Result# ");
1.126     brouard  5916:   for(i=1; i<=nlstate;i++)
                   5917:       fprintf(ficresvpl," %1d-%1d",i,i);
                   5918:   fprintf(ficresvpl,"\n");
                   5919: 
                   5920:   xp=vector(1,npar);
                   5921:   dnewm=matrix(1,nlstate,1,npar);
                   5922:   doldm=matrix(1,nlstate,1,nlstate);
                   5923:   
                   5924:   hstepm=1*YEARM; /* Every year of age */
                   5925:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   5926:   agelim = AGESUP;
                   5927:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5928:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5929:     if (stepm >= YEARM) hstepm=1;
                   5930:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   5931:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  5932:     mgp=matrix(1,npar,1,nlstate);
                   5933:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  5934:     gp=vector(1,nlstate);
                   5935:     gm=vector(1,nlstate);
                   5936: 
                   5937:     for(theta=1; theta <=npar; theta++){
                   5938:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   5939:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5940:       }
1.209     brouard  5941:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5942:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5943:       else
1.235     brouard  5944:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5945:       for(i=1;i<=nlstate;i++){
1.126     brouard  5946:        gp[i] = prlim[i][i];
1.208     brouard  5947:        mgp[theta][i] = prlim[i][i];
                   5948:       }
1.126     brouard  5949:       for(i=1; i<=npar; i++) /* Computes gradient */
                   5950:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  5951:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5952:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5953:       else
1.235     brouard  5954:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5955:       for(i=1;i<=nlstate;i++){
1.126     brouard  5956:        gm[i] = prlim[i][i];
1.208     brouard  5957:        mgm[theta][i] = prlim[i][i];
                   5958:       }
1.126     brouard  5959:       for(i=1;i<=nlstate;i++)
                   5960:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  5961:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  5962:     } /* End theta */
                   5963: 
                   5964:     trgradg =matrix(1,nlstate,1,npar);
                   5965: 
                   5966:     for(j=1; j<=nlstate;j++)
                   5967:       for(theta=1; theta <=npar; theta++)
                   5968:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  5969:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5970:     /*   printf("\nmgm mgp %d ",(int)age); */
                   5971:     /*   for(j=1; j<=nlstate;j++){ */
                   5972:     /*         printf(" %d ",j); */
                   5973:     /*         for(theta=1; theta <=npar; theta++) */
                   5974:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   5975:     /*         printf("\n "); */
                   5976:     /*   } */
                   5977:     /* } */
                   5978:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5979:     /*   printf("\n gradg %d ",(int)age); */
                   5980:     /*   for(j=1; j<=nlstate;j++){ */
                   5981:     /*         printf("%d ",j); */
                   5982:     /*         for(theta=1; theta <=npar; theta++) */
                   5983:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   5984:     /*         printf("\n "); */
                   5985:     /*   } */
                   5986:     /* } */
1.126     brouard  5987: 
                   5988:     for(i=1;i<=nlstate;i++)
                   5989:       varpl[i][(int)age] =0.;
1.209     brouard  5990:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.205     brouard  5991:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   5992:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
                   5993:     }else{
1.126     brouard  5994:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   5995:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  5996:     }
1.126     brouard  5997:     for(i=1;i<=nlstate;i++)
                   5998:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   5999: 
                   6000:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6001:     if(nresult >=1)
                   6002:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6003:     for(i=1; i<=nlstate;i++)
                   6004:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6005:     fprintf(ficresvpl,"\n");
                   6006:     free_vector(gp,1,nlstate);
                   6007:     free_vector(gm,1,nlstate);
1.208     brouard  6008:     free_matrix(mgm,1,npar,1,nlstate);
                   6009:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6010:     free_matrix(gradg,1,npar,1,nlstate);
                   6011:     free_matrix(trgradg,1,nlstate,1,npar);
                   6012:   } /* End age */
                   6013: 
                   6014:   free_vector(xp,1,npar);
                   6015:   free_matrix(doldm,1,nlstate,1,npar);
                   6016:   free_matrix(dnewm,1,nlstate,1,nlstate);
                   6017: 
                   6018: }
                   6019: 
                   6020: /************ Variance of one-step probabilities  ******************/
                   6021: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6022:  {
                   6023:    int i, j=0,  k1, l1, tj;
                   6024:    int k2, l2, j1,  z1;
                   6025:    int k=0, l;
                   6026:    int first=1, first1, first2;
                   6027:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6028:    double **dnewm,**doldm;
                   6029:    double *xp;
                   6030:    double *gp, *gm;
                   6031:    double **gradg, **trgradg;
                   6032:    double **mu;
                   6033:    double age, cov[NCOVMAX+1];
                   6034:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6035:    int theta;
                   6036:    char fileresprob[FILENAMELENGTH];
                   6037:    char fileresprobcov[FILENAMELENGTH];
                   6038:    char fileresprobcor[FILENAMELENGTH];
                   6039:    double ***varpij;
                   6040: 
                   6041:    strcpy(fileresprob,"PROB_"); 
                   6042:    strcat(fileresprob,fileres);
                   6043:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6044:      printf("Problem with resultfile: %s\n", fileresprob);
                   6045:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6046:    }
                   6047:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6048:    strcat(fileresprobcov,fileresu);
                   6049:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6050:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6051:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6052:    }
                   6053:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6054:    strcat(fileresprobcor,fileresu);
                   6055:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6056:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6057:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6058:    }
                   6059:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6060:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6061:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6062:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6063:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6064:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6065:    pstamp(ficresprob);
                   6066:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6067:    fprintf(ficresprob,"# Age");
                   6068:    pstamp(ficresprobcov);
                   6069:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6070:    fprintf(ficresprobcov,"# Age");
                   6071:    pstamp(ficresprobcor);
                   6072:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6073:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6074: 
                   6075: 
1.222     brouard  6076:    for(i=1; i<=nlstate;i++)
                   6077:      for(j=1; j<=(nlstate+ndeath);j++){
                   6078:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6079:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6080:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6081:      }  
                   6082:    /* fprintf(ficresprob,"\n");
                   6083:       fprintf(ficresprobcov,"\n");
                   6084:       fprintf(ficresprobcor,"\n");
                   6085:    */
                   6086:    xp=vector(1,npar);
                   6087:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6088:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6089:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6090:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6091:    first=1;
                   6092:    fprintf(ficgp,"\n# Routine varprob");
                   6093:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6094:    fprintf(fichtm,"\n");
                   6095: 
                   6096:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.</li>\n",optionfilehtmcov);
                   6097:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6098:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6099: and drawn. It helps understanding how is the covariance between two incidences.\
                   6100:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6101:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6102: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6103: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6104: standard deviations wide on each axis. <br>\
                   6105:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6106:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6107: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6108: 
1.222     brouard  6109:    cov[1]=1;
                   6110:    /* tj=cptcoveff; */
1.225     brouard  6111:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6112:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6113:    j1=0;
1.224     brouard  6114:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6115:      if  (cptcovn>0) {
                   6116:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6117:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6118:        fprintf(ficresprob, "**********\n#\n");
                   6119:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6120:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6121:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6122:                        
1.222     brouard  6123:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6124:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6125:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6126:                        
                   6127:                        
1.222     brouard  6128:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6129:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6130:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6131:                        
1.222     brouard  6132:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6133:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6134:        fprintf(ficresprobcor, "**********\n#");    
                   6135:        if(invalidvarcomb[j1]){
                   6136:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6137:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6138:         continue;
                   6139:        }
                   6140:      }
                   6141:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6142:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6143:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6144:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6145:      for (age=bage; age<=fage; age ++){ 
                   6146:        cov[2]=age;
                   6147:        if(nagesqr==1)
                   6148:         cov[3]= age*age;
                   6149:        for (k=1; k<=cptcovn;k++) {
                   6150:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6151:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6152:                                                                    * 1  1 1 1 1
                   6153:                                                                    * 2  2 1 1 1
                   6154:                                                                    * 3  1 2 1 1
                   6155:                                                                    */
                   6156:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6157:        }
                   6158:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6159:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6160:        for (k=1; k<=cptcovprod;k++)
                   6161:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6162:                        
                   6163:                        
1.222     brouard  6164:        for(theta=1; theta <=npar; theta++){
                   6165:         for(i=1; i<=npar; i++)
                   6166:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6167:                                
1.222     brouard  6168:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6169:                                
1.222     brouard  6170:         k=0;
                   6171:         for(i=1; i<= (nlstate); i++){
                   6172:           for(j=1; j<=(nlstate+ndeath);j++){
                   6173:             k=k+1;
                   6174:             gp[k]=pmmij[i][j];
                   6175:           }
                   6176:         }
1.220     brouard  6177:                                
1.222     brouard  6178:         for(i=1; i<=npar; i++)
                   6179:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6180:                                
1.222     brouard  6181:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6182:         k=0;
                   6183:         for(i=1; i<=(nlstate); i++){
                   6184:           for(j=1; j<=(nlstate+ndeath);j++){
                   6185:             k=k+1;
                   6186:             gm[k]=pmmij[i][j];
                   6187:           }
                   6188:         }
1.220     brouard  6189:                                
1.222     brouard  6190:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6191:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6192:        }
1.126     brouard  6193: 
1.222     brouard  6194:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6195:         for(theta=1; theta <=npar; theta++)
                   6196:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6197:                        
1.222     brouard  6198:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6199:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6200:                        
1.222     brouard  6201:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6202:                        
1.222     brouard  6203:        k=0;
                   6204:        for(i=1; i<=(nlstate); i++){
                   6205:         for(j=1; j<=(nlstate+ndeath);j++){
                   6206:           k=k+1;
                   6207:           mu[k][(int) age]=pmmij[i][j];
                   6208:         }
                   6209:        }
                   6210:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6211:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6212:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6213:                        
1.222     brouard  6214:        /*printf("\n%d ",(int)age);
                   6215:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6216:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6217:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6218:         }*/
1.220     brouard  6219:                        
1.222     brouard  6220:        fprintf(ficresprob,"\n%d ",(int)age);
                   6221:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6222:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6223:                        
1.222     brouard  6224:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6225:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6226:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6227:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6228:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6229:        }
                   6230:        i=0;
                   6231:        for (k=1; k<=(nlstate);k++){
                   6232:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6233:           i++;
                   6234:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6235:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6236:           for (j=1; j<=i;j++){
                   6237:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6238:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6239:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6240:           }
                   6241:         }
                   6242:        }/* end of loop for state */
                   6243:      } /* end of loop for age */
                   6244:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6245:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6246:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6247:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6248:     
                   6249:      /* Confidence intervalle of pij  */
                   6250:      /*
                   6251:        fprintf(ficgp,"\nunset parametric;unset label");
                   6252:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6253:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6254:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6255:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6256:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6257:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6258:      */
                   6259:                
                   6260:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6261:      first1=1;first2=2;
                   6262:      for (k2=1; k2<=(nlstate);k2++){
                   6263:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6264:         if(l2==k2) continue;
                   6265:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6266:         for (k1=1; k1<=(nlstate);k1++){
                   6267:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6268:             if(l1==k1) continue;
                   6269:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6270:             if(i<=j) continue;
                   6271:             for (age=bage; age<=fage; age ++){ 
                   6272:               if ((int)age %5==0){
                   6273:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6274:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6275:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6276:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6277:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6278:                 c12=cv12/sqrt(v1*v2);
                   6279:                 /* Computing eigen value of matrix of covariance */
                   6280:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6281:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6282:                 if ((lc2 <0) || (lc1 <0) ){
                   6283:                   if(first2==1){
                   6284:                     first1=0;
                   6285:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6286:                   }
                   6287:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6288:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6289:                   /* lc2=fabs(lc2); */
                   6290:                 }
1.220     brouard  6291:                                                                
1.222     brouard  6292:                 /* Eigen vectors */
                   6293:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   6294:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6295:                 v21=(lc1-v1)/cv12*v11;
                   6296:                 v12=-v21;
                   6297:                 v22=v11;
                   6298:                 tnalp=v21/v11;
                   6299:                 if(first1==1){
                   6300:                   first1=0;
                   6301:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6302:                 }
                   6303:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6304:                 /*printf(fignu*/
                   6305:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6306:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6307:                 if(first==1){
                   6308:                   first=0;
                   6309:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6310:                   fprintf(ficgp,"\nset parametric;unset label");
                   6311:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6312:                   fprintf(ficgp,"\nset ter svg size 640, 480");
                   6313:                   fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6314:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6315: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6316:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6317:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6318:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6319:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6320:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6321:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6322:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6323:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
                   6324:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                                                         \
                   6325:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6326:                 }else{
                   6327:                   first=0;
                   6328:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6329:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6330:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6331:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
                   6332:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                 \
                   6333:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6334:                 }/* if first */
                   6335:               } /* age mod 5 */
                   6336:             } /* end loop age */
                   6337:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6338:             first=1;
                   6339:           } /*l12 */
                   6340:         } /* k12 */
                   6341:        } /*l1 */
                   6342:      }/* k1 */
                   6343:    }  /* loop on combination of covariates j1 */
                   6344:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6345:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6346:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6347:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6348:    free_vector(xp,1,npar);
                   6349:    fclose(ficresprob);
                   6350:    fclose(ficresprobcov);
                   6351:    fclose(ficresprobcor);
                   6352:    fflush(ficgp);
                   6353:    fflush(fichtmcov);
                   6354:  }
1.126     brouard  6355: 
                   6356: 
                   6357: /******************* Printing html file ***********/
1.201     brouard  6358: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6359:                  int lastpass, int stepm, int weightopt, char model[],\
                   6360:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.217     brouard  6361:                  int popforecast, int prevfcast, int backcast, int estepm , \
1.213     brouard  6362:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   6363:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.237     brouard  6364:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6365: 
                   6366:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6367:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6368: </ul>");
1.237     brouard  6369:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6370: </ul>", model);
1.214     brouard  6371:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6372:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6373:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6374:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6375:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6376:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6377:    fprintf(fichtm,"\
                   6378:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6379:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6380:    fprintf(fichtm,"\
1.217     brouard  6381:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6382:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6383:    fprintf(fichtm,"\
1.126     brouard  6384:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6385:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6386:    fprintf(fichtm,"\
1.217     brouard  6387:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6388:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6389:    fprintf(fichtm,"\
1.211     brouard  6390:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6391:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6392:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6393:    if(prevfcast==1){
                   6394:      fprintf(fichtm,"\
                   6395:  - Prevalence projections by age and states:                           \
1.201     brouard  6396:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6397:    }
1.126     brouard  6398: 
1.222     brouard  6399:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
1.126     brouard  6400: 
1.225     brouard  6401:    m=pow(2,cptcoveff);
1.222     brouard  6402:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6403: 
1.222     brouard  6404:    jj1=0;
1.237     brouard  6405: 
                   6406:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6407:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6408:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6409:        continue;
1.220     brouard  6410: 
1.222     brouard  6411:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6412:      jj1++;
                   6413:      if (cptcovn > 0) {
                   6414:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6415:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6416:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6417:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6418:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6419:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6420:        }
1.237     brouard  6421:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6422:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6423:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6424:       }
                   6425:        
1.230     brouard  6426:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6427:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6428:        if(invalidvarcomb[k1]){
                   6429:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6430:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6431:         continue;
                   6432:        }
                   6433:      }
                   6434:      /* aij, bij */
1.241     brouard  6435:      fprintf(fichtm,"<br>- Logit model (yours is: 1+age+%s), for example: logit(pij)=log(pij/pii)= aij+ bij age + V1 age + etc. as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
                   6436: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6437:      /* Pij */
1.241     brouard  6438:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6439: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6440:      /* Quasi-incidences */
                   6441:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6442:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6443:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6444: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6445: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6446:      /* Survival functions (period) in state j */
                   6447:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6448:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6449: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6450:      }
                   6451:      /* State specific survival functions (period) */
                   6452:      for(cpt=1; cpt<=nlstate;cpt++){
                   6453:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6454:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.241     brouard  6455:  <a href=\"%s_%d-%d-%d.svg\">%s_%d%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6456:      }
                   6457:      /* Period (stable) prevalence in each health state */
                   6458:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6459:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6460: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6461:      }
                   6462:      if(backcast==1){
                   6463:        /* Period (stable) back prevalence in each health state */
                   6464:        for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6465:         fprintf(fichtm,"<br>\n- Convergence to period (stable) back prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6466: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6467:        }
1.217     brouard  6468:      }
1.222     brouard  6469:      if(prevfcast==1){
                   6470:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6471:        for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6472:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f) up to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6473: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6474:        }
                   6475:      }
1.220     brouard  6476:         
1.222     brouard  6477:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6478:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6479: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6480:      }
                   6481:      /* } /\* end i1 *\/ */
                   6482:    }/* End k1 */
                   6483:    fprintf(fichtm,"</ul>");
1.126     brouard  6484: 
1.222     brouard  6485:    fprintf(fichtm,"\
1.126     brouard  6486: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6487:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6488:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6489: But because parameters are usually highly correlated (a higher incidence of disability \
                   6490: and a higher incidence of recovery can give very close observed transition) it might \
                   6491: be very useful to look not only at linear confidence intervals estimated from the \
                   6492: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6493: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6494: covariance matrix of the one-step probabilities. \
                   6495: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6496: 
1.222     brouard  6497:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6498:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6499:    fprintf(fichtm,"\
1.126     brouard  6500:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6501:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6502: 
1.222     brouard  6503:    fprintf(fichtm,"\
1.126     brouard  6504:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6505:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6506:    fprintf(fichtm,"\
1.126     brouard  6507:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6508:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6509:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6510:    fprintf(fichtm,"\
1.126     brouard  6511:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6512:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6513:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6514:    fprintf(fichtm,"\
1.128     brouard  6515:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6516:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6517:    fprintf(fichtm,"\
1.128     brouard  6518:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6519:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6520:    fprintf(fichtm,"\
1.126     brouard  6521:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6522:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6523: 
                   6524: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6525: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6526: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6527: /*     <br>",fileres,fileres,fileres,fileres); */
                   6528: /*  else  */
                   6529: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6530:    fflush(fichtm);
                   6531:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6532: 
1.225     brouard  6533:    m=pow(2,cptcoveff);
1.222     brouard  6534:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6535: 
1.222     brouard  6536:    jj1=0;
1.237     brouard  6537: 
1.241     brouard  6538:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6539:    for(k1=1; k1<=m;k1++){
1.253     brouard  6540:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6541:        continue;
1.222     brouard  6542:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6543:      jj1++;
1.126     brouard  6544:      if (cptcovn > 0) {
                   6545:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6546:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6547:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6548:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6549:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6550:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6551:       }
                   6552: 
1.126     brouard  6553:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6554: 
1.222     brouard  6555:        if(invalidvarcomb[k1]){
                   6556:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6557:         continue;
                   6558:        }
1.126     brouard  6559:      }
                   6560:      for(cpt=1; cpt<=nlstate;cpt++) {
1.218     brouard  6561:        fprintf(fichtm,"\n<br>- Observed (cross-sectional) and period (incidence based) \
1.241     brouard  6562: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
                   6563: <img src=\"%s_%d-%d-%d.svg\">",cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  6564:      }
                   6565:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6566: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6567: true period expectancies (those weighted with period prevalences are also\
                   6568:  drawn in addition to the population based expectancies computed using\
1.241     brouard  6569:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   6570: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  6571:      /* } /\* end i1 *\/ */
                   6572:    }/* End k1 */
1.241     brouard  6573:   }/* End nres */
1.222     brouard  6574:    fprintf(fichtm,"</ul>");
                   6575:    fflush(fichtm);
1.126     brouard  6576: }
                   6577: 
                   6578: /******************* Gnuplot file **************/
1.223     brouard  6579: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[]){
1.126     brouard  6580: 
                   6581:   char dirfileres[132],optfileres[132];
1.223     brouard  6582:   char gplotcondition[132];
1.237     brouard  6583:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6584:   int lv=0, vlv=0, kl=0;
1.130     brouard  6585:   int ng=0;
1.201     brouard  6586:   int vpopbased;
1.223     brouard  6587:   int ioffset; /* variable offset for columns */
1.235     brouard  6588:   int nres=0; /* Index of resultline */
1.219     brouard  6589: 
1.126     brouard  6590: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6591: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6592: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6593: /*   } */
                   6594: 
                   6595:   /*#ifdef windows */
                   6596:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6597:   /*#endif */
1.225     brouard  6598:   m=pow(2,cptcoveff);
1.126     brouard  6599: 
1.202     brouard  6600:   /* Contribution to likelihood */
                   6601:   /* Plot the probability implied in the likelihood */
1.223     brouard  6602:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6603:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6604:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6605:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6606: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6607:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6608: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6609:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6610:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6611:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6612:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6613:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6614:   for (i=1; i<= nlstate ; i ++) {
                   6615:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6616:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6617:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6618:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6619:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6620:     }
                   6621:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6622:   }
                   6623:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6624:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6625:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6626:   fprintf(ficgp,"\nset out;unset log\n");
                   6627:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6628: 
1.126     brouard  6629:   strcpy(dirfileres,optionfilefiname);
                   6630:   strcpy(optfileres,"vpl");
1.223     brouard  6631:   /* 1eme*/
1.238     brouard  6632:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   6633:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  6634:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  6635:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  6636:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6637:          continue;
                   6638:        /* We are interested in selected combination by the resultline */
1.246     brouard  6639:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  6640:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
                   6641:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6642:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   6643:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6644:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6645:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6646:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   6647:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  6648:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  6649:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6650:        }
                   6651:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  6652:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  6653:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6654:        }       
1.246     brouard  6655:        /* printf("\n#\n"); */
1.238     brouard  6656:        fprintf(ficgp,"\n#\n");
                   6657:        if(invalidvarcomb[k1]){
                   6658:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6659:          continue;
                   6660:        }
1.235     brouard  6661:       
1.241     brouard  6662:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   6663:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
                   6664:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres);
1.235     brouard  6665:       
1.238     brouard  6666:        for (i=1; i<= nlstate ; i ++) {
                   6667:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6668:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   6669:        }
1.242     brouard  6670:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres);
1.238     brouard  6671:        for (i=1; i<= nlstate ; i ++) {
                   6672:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6673:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6674:        } 
1.242     brouard  6675:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); 
1.238     brouard  6676:        for (i=1; i<= nlstate ; i ++) {
                   6677:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6678:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6679:        }  
                   6680:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1));
                   6681:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   6682:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  6683:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  6684:          if(cptcoveff ==0){
1.245     brouard  6685:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  6686:          }else{
                   6687:            kl=0;
                   6688:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   6689:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6690:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6691:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6692:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6693:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  6694:              kl++;
1.238     brouard  6695:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6696:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6697:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6698:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6699:              if(k==cptcoveff){
1.245     brouard  6700:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  6701:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  6702:              }else{
                   6703:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   6704:                kl++;
                   6705:              }
                   6706:            } /* end covariate */
                   6707:          } /* end if no covariate */
                   6708:        } /* end if backcast */
                   6709:        fprintf(ficgp,"\nset out \n");
                   6710:       } /* nres */
1.201     brouard  6711:     } /* k1 */
                   6712:   } /* cpt */
1.235     brouard  6713: 
                   6714:   
1.126     brouard  6715:   /*2 eme*/
1.238     brouard  6716:   for (k1=1; k1<= m ; k1 ++){  
                   6717:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6718:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6719:        continue;
                   6720:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
                   6721:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  6722:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6723:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6724:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6725:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6726:        vlv= nbcode[Tvaraff[k]][lv];
                   6727:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6728:       }
1.237     brouard  6729:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  6730:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  6731:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  6732:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  6733:       }
1.211     brouard  6734:       fprintf(ficgp,"\n#\n");
1.223     brouard  6735:       if(invalidvarcomb[k1]){
                   6736:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6737:        continue;
                   6738:       }
1.219     brouard  6739:                        
1.241     brouard  6740:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  6741:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
                   6742:        if(vpopbased==0)
                   6743:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
                   6744:        else
                   6745:          fprintf(ficgp,"\nreplot ");
                   6746:        for (i=1; i<= nlstate+1 ; i ++) {
                   6747:          k=2*i;
                   6748:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1, vpopbased);
                   6749:          for (j=1; j<= nlstate+1 ; j ++) {
                   6750:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6751:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6752:          }   
                   6753:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   6754:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
                   6755:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6756:          for (j=1; j<= nlstate+1 ; j ++) {
                   6757:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6758:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6759:          }   
                   6760:          fprintf(ficgp,"\" t\"\" w l lt 0,");
                   6761:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6762:          for (j=1; j<= nlstate+1 ; j ++) {
                   6763:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6764:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6765:          }   
                   6766:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   6767:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   6768:        } /* state */
                   6769:       } /* vpopbased */
1.244     brouard  6770:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  6771:     } /* end nres */
                   6772:   } /* k1 end 2 eme*/
                   6773:        
                   6774:        
                   6775:   /*3eme*/
                   6776:   for (k1=1; k1<= m ; k1 ++){
                   6777:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6778:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6779:        continue;
                   6780: 
                   6781:       for (cpt=1; cpt<= nlstate ; cpt ++) {
                   6782:        fprintf(ficgp,"\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
                   6783:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6784:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6785:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6786:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6787:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6788:          vlv= nbcode[Tvaraff[k]][lv];
                   6789:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6790:        }
                   6791:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6792:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6793:        }       
                   6794:        fprintf(ficgp,"\n#\n");
                   6795:        if(invalidvarcomb[k1]){
                   6796:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6797:          continue;
                   6798:        }
                   6799:                        
                   6800:        /*       k=2+nlstate*(2*cpt-2); */
                   6801:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  6802:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.238     brouard  6803:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.201     brouard  6804: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),k1-1,k1-1,k,cpt);
1.238     brouard  6805:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6806:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6807:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   6808:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6809:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6810:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  6811:                                
1.238     brouard  6812:        */
                   6813:        for (i=1; i< nlstate ; i ++) {
                   6814:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+i,cpt,i+1);
                   6815:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  6816:                                
1.238     brouard  6817:        } 
                   6818:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+nlstate,cpt);
                   6819:       }
                   6820:     } /* end nres */
                   6821:   } /* end kl 3eme */
1.126     brouard  6822:   
1.223     brouard  6823:   /* 4eme */
1.201     brouard  6824:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  6825:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   6826:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6827:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  6828:        continue;
1.238     brouard  6829:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
                   6830:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   6831:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6832:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6833:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6834:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6835:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6836:          vlv= nbcode[Tvaraff[k]][lv];
                   6837:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6838:        }
                   6839:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6840:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6841:        }       
                   6842:        fprintf(ficgp,"\n#\n");
                   6843:        if(invalidvarcomb[k1]){
                   6844:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6845:          continue;
1.223     brouard  6846:        }
1.238     brouard  6847:       
1.241     brouard  6848:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.238     brouard  6849:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6850: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6851:        k=3;
                   6852:        for (i=1; i<= nlstate ; i ++){
                   6853:          if(i==1){
                   6854:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6855:          }else{
                   6856:            fprintf(ficgp,", '' ");
                   6857:          }
                   6858:          l=(nlstate+ndeath)*(i-1)+1;
                   6859:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6860:          for (j=2; j<= nlstate+ndeath ; j ++)
                   6861:            fprintf(ficgp,"+$%d",k+l+j-1);
                   6862:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   6863:        } /* nlstate */
                   6864:        fprintf(ficgp,"\nset out\n");
                   6865:       } /* end cpt state*/ 
                   6866:     } /* end nres */
                   6867:   } /* end covariate k1 */  
                   6868: 
1.220     brouard  6869: /* 5eme */
1.201     brouard  6870:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  6871:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   6872:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6873:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  6874:        continue;
1.238     brouard  6875:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
                   6876:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   6877:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6878:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6879:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6880:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6881:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6882:          vlv= nbcode[Tvaraff[k]][lv];
                   6883:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6884:        }
                   6885:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6886:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6887:        }       
                   6888:        fprintf(ficgp,"\n#\n");
                   6889:        if(invalidvarcomb[k1]){
                   6890:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6891:          continue;
                   6892:        }
1.227     brouard  6893:       
1.241     brouard  6894:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.238     brouard  6895:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6896: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6897:        k=3;
                   6898:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6899:          if(j==1)
                   6900:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6901:          else
                   6902:            fprintf(ficgp,", '' ");
                   6903:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6904:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   6905:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   6906:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   6907:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   6908:        } /* nlstate */
                   6909:        fprintf(ficgp,", '' ");
                   6910:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   6911:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6912:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6913:          if(j < nlstate)
                   6914:            fprintf(ficgp,"$%d +",k+l);
                   6915:          else
                   6916:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   6917:        }
                   6918:        fprintf(ficgp,"\nset out\n");
                   6919:       } /* end cpt state*/ 
                   6920:     } /* end covariate */  
                   6921:   } /* end nres */
1.227     brouard  6922:   
1.220     brouard  6923: /* 6eme */
1.202     brouard  6924:   /* CV preval stable (period) for each covariate */
1.237     brouard  6925:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6926:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6927:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6928:       continue;
1.153     brouard  6929:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6930:       
1.211     brouard  6931:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  6932:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  6933:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6934:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6935:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6936:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6937:        vlv= nbcode[Tvaraff[k]][lv];
                   6938:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6939:       }
1.237     brouard  6940:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6941:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6942:       }        
1.211     brouard  6943:       fprintf(ficgp,"\n#\n");
1.223     brouard  6944:       if(invalidvarcomb[k1]){
1.227     brouard  6945:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6946:        continue;
1.223     brouard  6947:       }
1.227     brouard  6948:       
1.241     brouard  6949:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.126     brouard  6950:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  6951: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6952:       k=3; /* Offset */
1.153     brouard  6953:       for (i=1; i<= nlstate ; i ++){
1.227     brouard  6954:        if(i==1)
                   6955:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6956:        else
                   6957:          fprintf(ficgp,", '' ");
                   6958:        l=(nlstate+ndeath)*(i-1)+1;
                   6959:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6960:        for (j=2; j<= nlstate ; j ++)
                   6961:          fprintf(ficgp,"+$%d",k+l+j-1);
                   6962:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  6963:       } /* nlstate */
1.201     brouard  6964:       fprintf(ficgp,"\nset out\n");
1.153     brouard  6965:     } /* end cpt state*/ 
                   6966:   } /* end covariate */  
1.227     brouard  6967:   
                   6968:   
1.220     brouard  6969: /* 7eme */
1.218     brouard  6970:   if(backcast == 1){
1.217     brouard  6971:     /* CV back preval stable (period) for each covariate */
1.237     brouard  6972:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6973:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6974:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6975:        continue;
1.218     brouard  6976:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6977:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
                   6978:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6979:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6980:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6981:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  6982:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  6983:          vlv= nbcode[Tvaraff[k]][lv];
                   6984:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6985:        }
1.237     brouard  6986:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6987:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6988:        }       
1.227     brouard  6989:        fprintf(ficgp,"\n#\n");
                   6990:        if(invalidvarcomb[k1]){
                   6991:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6992:          continue;
                   6993:        }
                   6994:        
1.241     brouard  6995:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.227     brouard  6996:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  6997: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  6998:        k=3; /* Offset */
                   6999:        for (i=1; i<= nlstate ; i ++){
                   7000:          if(i==1)
                   7001:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7002:          else
                   7003:            fprintf(ficgp,", '' ");
                   7004:          /* l=(nlstate+ndeath)*(i-1)+1; */
                   7005:          l=(nlstate+ndeath)*(cpt-1)+1;
                   7006:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7007:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
                   7008:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+(cpt-1)+i-1); /* a vérifier */
                   7009:          /* for (j=2; j<= nlstate ; j ++) */
                   7010:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7011:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
                   7012:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",i,cpt);
                   7013:        } /* nlstate */
                   7014:        fprintf(ficgp,"\nset out\n");
1.218     brouard  7015:       } /* end cpt state*/ 
                   7016:     } /* end covariate */  
                   7017:   } /* End if backcast */
                   7018:   
1.223     brouard  7019:   /* 8eme */
1.218     brouard  7020:   if(prevfcast==1){
                   7021:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7022:     
1.237     brouard  7023:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7024:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7025:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7026:        continue;
1.211     brouard  7027:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  7028:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7029:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7030:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7031:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7032:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7033:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7034:          vlv= nbcode[Tvaraff[k]][lv];
                   7035:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7036:        }
1.237     brouard  7037:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7038:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7039:        }       
1.227     brouard  7040:        fprintf(ficgp,"\n#\n");
                   7041:        if(invalidvarcomb[k1]){
                   7042:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7043:          continue;
                   7044:        }
                   7045:        
                   7046:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7047:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.227     brouard  7048:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7049: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7050:        for (i=1; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7051:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7052:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7053:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7054:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7055:          if(i==1){
                   7056:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7057:          }else{
                   7058:            fprintf(ficgp,",\\\n '' ");
                   7059:          }
                   7060:          if(cptcoveff ==0){ /* No covariate */
                   7061:            ioffset=2; /* Age is in 2 */
                   7062:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7063:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7064:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7065:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7066:            fprintf(ficgp," u %d:(", ioffset); 
                   7067:            if(i==nlstate+1)
                   7068:              fprintf(ficgp," $%d/(1.-$%d)) t 'pw.%d' with line ",      \
                   7069:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7070:            else
                   7071:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7072:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7073:          }else{ /* more than 2 covariates */
                   7074:            if(cptcoveff ==1){
                   7075:              ioffset=4; /* Age is in 4 */
                   7076:            }else{
                   7077:              ioffset=6; /* Age is in 6 */
                   7078:              /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7079:              /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7080:            }   
                   7081:            fprintf(ficgp," u %d:(",ioffset); 
                   7082:            kl=0;
                   7083:            strcpy(gplotcondition,"(");
                   7084:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7085:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7086:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7087:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7088:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7089:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7090:              kl++;
                   7091:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7092:              kl++;
                   7093:              if(k <cptcoveff && cptcoveff>1)
                   7094:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7095:            }
                   7096:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7097:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7098:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7099:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7100:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7101:            if(i==nlstate+1){
                   7102:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p.%d' with line ", gplotcondition, \
                   7103:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7104:            }else{
                   7105:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7106:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7107:            }
                   7108:          } /* end if covariate */
                   7109:        } /* nlstate */
                   7110:        fprintf(ficgp,"\nset out\n");
1.223     brouard  7111:       } /* end cpt state*/
                   7112:     } /* end covariate */
                   7113:   } /* End if prevfcast */
1.227     brouard  7114:   
                   7115:   
1.238     brouard  7116:   /* 9eme writing MLE parameters */
                   7117:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7118:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7119:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7120:     for(k=1; k <=(nlstate+ndeath); k++){
                   7121:       if (k != i) {
1.227     brouard  7122:        fprintf(ficgp,"#   current state %d\n",k);
                   7123:        for(j=1; j <=ncovmodel; j++){
                   7124:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7125:          jk++; 
                   7126:        }
                   7127:        fprintf(ficgp,"\n");
1.126     brouard  7128:       }
                   7129:     }
1.223     brouard  7130:   }
1.187     brouard  7131:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7132:   
1.145     brouard  7133:   /*goto avoid;*/
1.238     brouard  7134:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7135:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7136:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7137:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7138:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7139:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7140:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7141:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7142:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7143:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7144:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7145:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7146:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7147:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7148:   fprintf(ficgp,"#\n");
1.223     brouard  7149:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7150:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7151:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7152:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.237     brouard  7153:     fprintf(ficgp,"#   jk=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7154:     for(jk=1; jk <=m; jk++)  /* For each combination of covariate */
                   7155:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7156:       if(m != 1 && TKresult[nres]!= jk)
1.237     brouard  7157:        continue;
                   7158:       fprintf(ficgp,"# Combination of dummy  jk=%d and ",jk);
                   7159:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7160:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7161:       }        
                   7162:       fprintf(ficgp,"\n#\n");
1.241     brouard  7163:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng,nres);
1.223     brouard  7164:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7165:       if (ng==1){
                   7166:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7167:        fprintf(ficgp,"\nunset log y");
                   7168:       }else if (ng==2){
                   7169:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7170:        fprintf(ficgp,"\nset log y");
                   7171:       }else if (ng==3){
                   7172:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7173:        fprintf(ficgp,"\nset log y");
                   7174:       }else
                   7175:        fprintf(ficgp,"\nunset title ");
                   7176:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7177:       i=1;
                   7178:       for(k2=1; k2<=nlstate; k2++) {
                   7179:        k3=i;
                   7180:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7181:          if (k != k2){
                   7182:            switch( ng) {
                   7183:            case 1:
                   7184:              if(nagesqr==0)
                   7185:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7186:              else /* nagesqr =1 */
                   7187:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7188:              break;
                   7189:            case 2: /* ng=2 */
                   7190:              if(nagesqr==0)
                   7191:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7192:              else /* nagesqr =1 */
                   7193:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7194:              break;
                   7195:            case 3:
                   7196:              if(nagesqr==0)
                   7197:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7198:              else /* nagesqr =1 */
                   7199:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7200:              break;
                   7201:            }
                   7202:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7203:            ijp=1; /* product no age */
                   7204:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7205:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7206:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.237     brouard  7207:              if(j==Tage[ij]) { /* Product by age */
                   7208:                if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
1.238     brouard  7209:                  if(DummyV[j]==0){
1.237     brouard  7210:                    fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7211:                  }else{ /* quantitative */
                   7212:                    fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7213:                    /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7214:                  }
                   7215:                  ij++;
                   7216:                }
                   7217:              }else if(j==Tprod[ijp]) { /* */ 
                   7218:                /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7219:                if(ijp <=cptcovprod) { /* Product */
1.238     brouard  7220:                  if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7221:                    if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
1.237     brouard  7222:                      /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],nbcode[Tvard[ijp][2]][codtabm(jk,j)]); */
                   7223:                      fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7224:                    }else{ /* Vn is dummy and Vm is quanti */
                   7225:                      /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7226:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7227:                    }
                   7228:                  }else{ /* Vn*Vm Vn is quanti */
1.238     brouard  7229:                    if(DummyV[Tvard[ijp][2]]==0){
1.237     brouard  7230:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7231:                    }else{ /* Both quanti */
                   7232:                      fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7233:                    }
                   7234:                  }
1.238     brouard  7235:                  ijp++;
1.237     brouard  7236:                }
                   7237:              } else{  /* simple covariate */
                   7238:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(jk,j)]); /\* Valgrind bug nbcode *\/ */
                   7239:                if(Dummy[j]==0){
                   7240:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7241:                }else{ /* quantitative */
                   7242:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.223     brouard  7243:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7244:                }
1.237     brouard  7245:              } /* end simple */
                   7246:            } /* end j */
1.223     brouard  7247:          }else{
                   7248:            i=i-ncovmodel;
                   7249:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7250:              fprintf(ficgp," (1.");
                   7251:          }
1.227     brouard  7252:          
1.223     brouard  7253:          if(ng != 1){
                   7254:            fprintf(ficgp,")/(1");
1.227     brouard  7255:            
1.223     brouard  7256:            for(k1=1; k1 <=nlstate; k1++){ 
                   7257:              if(nagesqr==0)
                   7258:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                   7259:              else /* nagesqr =1 */
                   7260:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1,k3+(k1-1)*ncovmodel+1+nagesqr);
1.217     brouard  7261:               
1.223     brouard  7262:              ij=1;
                   7263:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.237     brouard  7264:                if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7265:                  if(ij <=cptcovage) { /* Bug valgrind */
1.223     brouard  7266:                    fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                   7267:                    /* fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7268:                    ij++;
                   7269:                  }
                   7270:                }
                   7271:                else
1.225     brouard  7272:                  fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7273:              }
                   7274:              fprintf(ficgp,")");
                   7275:            }
                   7276:            fprintf(ficgp,")");
                   7277:            if(ng ==2)
                   7278:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   7279:            else /* ng= 3 */
                   7280:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   7281:          }else{ /* end ng <> 1 */
                   7282:            if( k !=k2) /* logit p11 is hard to draw */
                   7283:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   7284:          }
                   7285:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7286:            fprintf(ficgp,",");
                   7287:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7288:            fprintf(ficgp,",");
                   7289:          i=i+ncovmodel;
                   7290:        } /* end k */
                   7291:       } /* end k2 */
                   7292:       fprintf(ficgp,"\n set out\n");
                   7293:     } /* end jk */
                   7294:   } /* end ng */
                   7295:   /* avoid: */
                   7296:   fflush(ficgp); 
1.126     brouard  7297: }  /* end gnuplot */
                   7298: 
                   7299: 
                   7300: /*************** Moving average **************/
1.219     brouard  7301: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  7302:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  7303:    
1.222     brouard  7304:    int i, cpt, cptcod;
                   7305:    int modcovmax =1;
                   7306:    int mobilavrange, mob;
                   7307:    int iage=0;
                   7308: 
                   7309:    double sum=0.;
                   7310:    double age;
                   7311:    double *sumnewp, *sumnewm;
                   7312:    double *agemingood, *agemaxgood; /* Currently identical for all covariates */
                   7313:   
                   7314:   
1.225     brouard  7315:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  7316:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   7317: 
                   7318:    sumnewp = vector(1,ncovcombmax);
                   7319:    sumnewm = vector(1,ncovcombmax);
                   7320:    agemingood = vector(1,ncovcombmax); 
                   7321:    agemaxgood = vector(1,ncovcombmax);
                   7322: 
                   7323:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7324:      sumnewm[cptcod]=0.;
                   7325:      sumnewp[cptcod]=0.;
                   7326:      agemingood[cptcod]=0;
                   7327:      agemaxgood[cptcod]=0;
                   7328:    }
                   7329:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   7330:   
                   7331:    if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   7332:      if(mobilav==1) mobilavrange=5; /* default */
                   7333:      else mobilavrange=mobilav;
                   7334:      for (age=bage; age<=fage; age++)
                   7335:        for (i=1; i<=nlstate;i++)
                   7336:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   7337:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   7338:      /* We keep the original values on the extreme ages bage, fage and for 
                   7339:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   7340:        we use a 5 terms etc. until the borders are no more concerned. 
                   7341:      */ 
                   7342:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   7343:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
                   7344:         for (i=1; i<=nlstate;i++){
                   7345:           for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7346:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   7347:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   7348:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   7349:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   7350:             }
                   7351:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
                   7352:           }
                   7353:         }
                   7354:        }/* end age */
                   7355:      }/* end mob */
                   7356:    }else
                   7357:      return -1;
                   7358:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7359:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7360:      if(invalidvarcomb[cptcod]){
                   7361:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7362:        continue;
                   7363:      }
1.219     brouard  7364: 
1.222     brouard  7365:      agemingood[cptcod]=fage-(mob-1)/2;
                   7366:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, finding the youngest wrong */
                   7367:        sumnewm[cptcod]=0.;
                   7368:        for (i=1; i<=nlstate;i++){
                   7369:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7370:        }
                   7371:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7372:         agemingood[cptcod]=age;
                   7373:        }else{ /* bad */
                   7374:         for (i=1; i<=nlstate;i++){
                   7375:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7376:         } /* i */
                   7377:        } /* end bad */
                   7378:      }/* age */
                   7379:      sum=0.;
                   7380:      for (i=1; i<=nlstate;i++){
                   7381:        sum+=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7382:      }
                   7383:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7384:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any descending age!\n",cptcod);
                   7385:        /* for (i=1; i<=nlstate;i++){ */
                   7386:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7387:        /* } /\* i *\/ */
                   7388:      } /* end bad */
                   7389:      /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   7390:      /* From youngest, finding the oldest wrong */
                   7391:      agemaxgood[cptcod]=bage+(mob-1)/2;
                   7392:      for (age=bage+(mob-1)/2; age<=fage; age++){
                   7393:        sumnewm[cptcod]=0.;
                   7394:        for (i=1; i<=nlstate;i++){
                   7395:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7396:        }
                   7397:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7398:         agemaxgood[cptcod]=age;
                   7399:        }else{ /* bad */
                   7400:         for (i=1; i<=nlstate;i++){
                   7401:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7402:         } /* i */
                   7403:        } /* end bad */
                   7404:      }/* age */
                   7405:      sum=0.;
                   7406:      for (i=1; i<=nlstate;i++){
                   7407:        sum+=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7408:      }
                   7409:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7410:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any ascending age!\n",cptcod);
                   7411:        /* for (i=1; i<=nlstate;i++){ */
                   7412:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7413:        /* } /\* i *\/ */
                   7414:      } /* end bad */
                   7415:                
                   7416:      for (age=bage; age<=fage; age++){
1.235     brouard  7417:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  7418:        sumnewp[cptcod]=0.;
                   7419:        sumnewm[cptcod]=0.;
                   7420:        for (i=1; i<=nlstate;i++){
                   7421:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   7422:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7423:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   7424:        }
                   7425:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   7426:      }
                   7427:      /* printf("\n"); */
                   7428:      /* } */
                   7429:      /* brutal averaging */
                   7430:      for (i=1; i<=nlstate;i++){
                   7431:        for (age=1; age<=bage; age++){
                   7432:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7433:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7434:        }       
                   7435:        for (age=fage; age<=AGESUP; age++){
                   7436:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7437:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7438:        }
                   7439:      } /* end i status */
                   7440:      for (i=nlstate+1; i<=nlstate+ndeath;i++){
                   7441:        for (age=1; age<=AGESUP; age++){
                   7442:         /*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*/
                   7443:         mobaverage[(int)age][i][cptcod]=0.;
                   7444:        }
                   7445:      }
                   7446:    }/* end cptcod */
                   7447:    free_vector(sumnewm,1, ncovcombmax);
                   7448:    free_vector(sumnewp,1, ncovcombmax);
                   7449:    free_vector(agemaxgood,1, ncovcombmax);
                   7450:    free_vector(agemingood,1, ncovcombmax);
                   7451:    return 0;
                   7452:  }/* End movingaverage */
1.218     brouard  7453:  
1.126     brouard  7454: 
                   7455: /************** Forecasting ******************/
1.235     brouard  7456:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  7457:   /* proj1, year, month, day of starting projection 
                   7458:      agemin, agemax range of age
                   7459:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   7460:      anproj2 year of en of projection (same day and month as proj1).
                   7461:   */
1.235     brouard  7462:    int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  7463:   double agec; /* generic age */
                   7464:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   7465:   double *popeffectif,*popcount;
                   7466:   double ***p3mat;
1.218     brouard  7467:   /* double ***mobaverage; */
1.126     brouard  7468:   char fileresf[FILENAMELENGTH];
                   7469: 
                   7470:   agelim=AGESUP;
1.211     brouard  7471:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   7472:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   7473:      We still use firstpass and lastpass as another selection.
                   7474:   */
1.214     brouard  7475:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   7476:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  7477:  
1.201     brouard  7478:   strcpy(fileresf,"F_"); 
                   7479:   strcat(fileresf,fileresu);
1.126     brouard  7480:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   7481:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   7482:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   7483:   }
1.235     brouard  7484:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   7485:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  7486: 
1.225     brouard  7487:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  7488: 
                   7489: 
                   7490:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   7491:   if (stepm<=12) stepsize=1;
                   7492:   if(estepm < stepm){
                   7493:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   7494:   }
                   7495:   else  hstepm=estepm;   
                   7496: 
                   7497:   hstepm=hstepm/stepm; 
                   7498:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   7499:                                fractional in yp1 */
                   7500:   anprojmean=yp;
                   7501:   yp2=modf((yp1*12),&yp);
                   7502:   mprojmean=yp;
                   7503:   yp1=modf((yp2*30.5),&yp);
                   7504:   jprojmean=yp;
                   7505:   if(jprojmean==0) jprojmean=1;
                   7506:   if(mprojmean==0) jprojmean=1;
                   7507: 
1.227     brouard  7508:   i1=pow(2,cptcoveff);
1.126     brouard  7509:   if (cptcovn < 1){i1=1;}
                   7510:   
                   7511:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   7512:   
                   7513:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  7514:   
1.126     brouard  7515: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  7516:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7517:   for(k=1; k<=i1;k++){
1.253     brouard  7518:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  7519:       continue;
1.227     brouard  7520:     if(invalidvarcomb[k]){
                   7521:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   7522:       continue;
                   7523:     }
                   7524:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   7525:     for(j=1;j<=cptcoveff;j++) {
                   7526:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7527:     }
1.235     brouard  7528:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7529:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  7530:     }
1.227     brouard  7531:     fprintf(ficresf," yearproj age");
                   7532:     for(j=1; j<=nlstate+ndeath;j++){ 
                   7533:       for(i=1; i<=nlstate;i++)               
                   7534:        fprintf(ficresf," p%d%d",i,j);
                   7535:       fprintf(ficresf," wp.%d",j);
                   7536:     }
                   7537:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   7538:       fprintf(ficresf,"\n");
                   7539:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
                   7540:       for (agec=fage; agec>=(ageminpar-1); agec--){ 
                   7541:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   7542:        nhstepm = nhstepm/hstepm; 
                   7543:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7544:        oldm=oldms;savm=savms;
1.235     brouard  7545:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.227     brouard  7546:        
                   7547:        for (h=0; h<=nhstepm; h++){
                   7548:          if (h*hstepm/YEARM*stepm ==yearp) {
                   7549:            fprintf(ficresf,"\n");
                   7550:            for(j=1;j<=cptcoveff;j++) 
                   7551:              fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7552:            fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   7553:          } 
                   7554:          for(j=1; j<=nlstate+ndeath;j++) {
                   7555:            ppij=0.;
                   7556:            for(i=1; i<=nlstate;i++) {
                   7557:              if (mobilav==1) 
                   7558:                ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][k];
                   7559:              else {
                   7560:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   7561:              }
                   7562:              if (h*hstepm/YEARM*stepm== yearp) {
                   7563:                fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   7564:              }
                   7565:            } /* end i */
                   7566:            if (h*hstepm/YEARM*stepm==yearp) {
                   7567:              fprintf(ficresf," %.3f", ppij);
                   7568:            }
                   7569:          }/* end j */
                   7570:        } /* end h */
                   7571:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7572:       } /* end agec */
                   7573:     } /* end yearp */
                   7574:   } /* end  k */
1.219     brouard  7575:        
1.126     brouard  7576:   fclose(ficresf);
1.215     brouard  7577:   printf("End of Computing forecasting \n");
                   7578:   fprintf(ficlog,"End of Computing forecasting\n");
                   7579: 
1.126     brouard  7580: }
                   7581: 
1.218     brouard  7582: /* /\************** Back Forecasting ******************\/ */
1.225     brouard  7583: /* void prevbackforecast(char fileres[], double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
1.218     brouard  7584: /*   /\* back1, year, month, day of starting backection  */
                   7585: /*      agemin, agemax range of age */
                   7586: /*      dateprev1 dateprev2 range of dates during which prevalence is computed */
                   7587: /*      anback2 year of en of backection (same day and month as back1). */
                   7588: /*   *\/ */
                   7589: /*   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1; */
                   7590: /*   double agec; /\* generic age *\/ */
                   7591: /*   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean; */
                   7592: /*   double *popeffectif,*popcount; */
                   7593: /*   double ***p3mat; */
                   7594: /*   /\* double ***mobaverage; *\/ */
                   7595: /*   char fileresfb[FILENAMELENGTH]; */
                   7596:        
                   7597: /*   agelim=AGESUP; */
                   7598: /*   /\* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people */
                   7599: /*      in each health status at the date of interview (if between dateprev1 and dateprev2). */
                   7600: /*      We still use firstpass and lastpass as another selection. */
                   7601: /*   *\/ */
                   7602: /*   /\* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ *\/ */
                   7603: /*   /\*             firstpass, lastpass,  stepm,  weightopt, model); *\/ */
                   7604: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   7605:        
                   7606: /*   strcpy(fileresfb,"FB_");  */
                   7607: /*   strcat(fileresfb,fileresu); */
                   7608: /*   if((ficresfb=fopen(fileresfb,"w"))==NULL) { */
                   7609: /*     printf("Problem with back forecast resultfile: %s\n", fileresfb); */
                   7610: /*     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb); */
                   7611: /*   } */
                   7612: /*   printf("Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7613: /*   fprintf(ficlog,"Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7614:        
1.225     brouard  7615: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.218     brouard  7616:        
                   7617: /*   /\* if (mobilav!=0) { *\/ */
                   7618: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7619: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7620: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7621: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7622: /*   /\*   } *\/ */
                   7623: /*   /\* } *\/ */
                   7624:        
                   7625: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7626: /*   if (stepm<=12) stepsize=1; */
                   7627: /*   if(estepm < stepm){ */
                   7628: /*     printf ("Problem %d lower than %d\n",estepm, stepm); */
                   7629: /*   } */
                   7630: /*   else  hstepm=estepm;    */
                   7631:        
                   7632: /*   hstepm=hstepm/stepm;  */
                   7633: /*   yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   7634: /*                                fractional in yp1 *\/ */
                   7635: /*   anprojmean=yp; */
                   7636: /*   yp2=modf((yp1*12),&yp); */
                   7637: /*   mprojmean=yp; */
                   7638: /*   yp1=modf((yp2*30.5),&yp); */
                   7639: /*   jprojmean=yp; */
                   7640: /*   if(jprojmean==0) jprojmean=1; */
                   7641: /*   if(mprojmean==0) jprojmean=1; */
                   7642:        
1.225     brouard  7643: /*   i1=cptcoveff; */
1.218     brouard  7644: /*   if (cptcovn < 1){i1=1;} */
1.217     brouard  7645:   
1.218     brouard  7646: /*   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);  */
1.217     brouard  7647:   
1.218     brouard  7648: /*   fprintf(ficresfb,"#****** Routine prevbackforecast **\n"); */
                   7649:        
                   7650: /*     /\*           if (h==(int)(YEARM*yearp)){ *\/ */
                   7651: /*   for(cptcov=1, k=0;cptcov<=i1;cptcov++){ */
1.225     brouard  7652: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
1.218     brouard  7653: /*       k=k+1; */
                   7654: /*       fprintf(ficresfb,"\n#****** hbijx=probability over h years, hp.jx is weighted by observed prev \n#"); */
1.225     brouard  7655: /*       for(j=1;j<=cptcoveff;j++) { */
1.218     brouard  7656: /*                             fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7657: /*       } */
                   7658: /*       fprintf(ficresfb," yearbproj age"); */
                   7659: /*       for(j=1; j<=nlstate+ndeath;j++){  */
                   7660: /*                             for(i=1; i<=nlstate;i++)               */
                   7661: /*           fprintf(ficresfb," p%d%d",i,j); */
                   7662: /*                             fprintf(ficresfb," p.%d",j); */
                   7663: /*       } */
                   7664: /*       for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {  */
                   7665: /*                             /\* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  *\/ */
                   7666: /*                             fprintf(ficresfb,"\n"); */
                   7667: /*                             fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);    */
                   7668: /*                             for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   7669: /*                                     nhstepm=(int) rint((agelim-agec)*YEARM/stepm);  */
                   7670: /*                                     nhstepm = nhstepm/hstepm;  */
                   7671: /*                                     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7672: /*                                     oldm=oldms;savm=savms; */
                   7673: /*                                     hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm,oldm,savm, dnewm, doldm, dsavm, k);       */
                   7674: /*                                     for (h=0; h<=nhstepm; h++){ */
                   7675: /*                                             if (h*hstepm/YEARM*stepm ==yearp) { */
                   7676: /*               fprintf(ficresfb,"\n"); */
1.225     brouard  7677: /*               for(j=1;j<=cptcoveff;j++)  */
1.218     brouard  7678: /*                 fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7679: /*                                                     fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec+h*hstepm/YEARM*stepm); */
                   7680: /*                                             }  */
                   7681: /*                                             for(j=1; j<=nlstate+ndeath;j++) { */
                   7682: /*                                                     ppij=0.; */
                   7683: /*                                                     for(i=1; i<=nlstate;i++) { */
                   7684: /*                                                             if (mobilav==1)  */
                   7685: /*                                                                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod]; */
                   7686: /*                                                             else { */
                   7687: /*                                                                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod]; */
                   7688: /*                                                             } */
                   7689: /*                                                             if (h*hstepm/YEARM*stepm== yearp) { */
                   7690: /*                                                                     fprintf(ficresfb," %.3f", p3mat[i][j][h]); */
                   7691: /*                                                             } */
                   7692: /*                                                     } /\* end i *\/ */
                   7693: /*                                                     if (h*hstepm/YEARM*stepm==yearp) { */
                   7694: /*                                                             fprintf(ficresfb," %.3f", ppij); */
                   7695: /*                                                     } */
                   7696: /*                                             }/\* end j *\/ */
                   7697: /*                                     } /\* end h *\/ */
                   7698: /*                                     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7699: /*                             } /\* end agec *\/ */
                   7700: /*       } /\* end yearp *\/ */
                   7701: /*     } /\* end cptcod *\/ */
                   7702: /*   } /\* end  cptcov *\/ */
                   7703:        
                   7704: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7705:        
                   7706: /*   fclose(ficresfb); */
                   7707: /*   printf("End of Computing Back forecasting \n"); */
                   7708: /*   fprintf(ficlog,"End of Computing Back forecasting\n"); */
1.217     brouard  7709:        
1.218     brouard  7710: /* } */
1.217     brouard  7711: 
1.126     brouard  7712: /************** Forecasting *****not tested NB*************/
1.227     brouard  7713: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  7714:   
1.227     brouard  7715: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   7716: /*   int *popage; */
                   7717: /*   double calagedatem, agelim, kk1, kk2; */
                   7718: /*   double *popeffectif,*popcount; */
                   7719: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   7720: /*   /\* double ***mobaverage; *\/ */
                   7721: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  7722: 
1.227     brouard  7723: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7724: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7725: /*   agelim=AGESUP; */
                   7726: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  7727:   
1.227     brouard  7728: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  7729:   
                   7730:   
1.227     brouard  7731: /*   strcpy(filerespop,"POP_");  */
                   7732: /*   strcat(filerespop,fileresu); */
                   7733: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   7734: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   7735: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   7736: /*   } */
                   7737: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   7738: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  7739: 
1.227     brouard  7740: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  7741: 
1.227     brouard  7742: /*   /\* if (mobilav!=0) { *\/ */
                   7743: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7744: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7745: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7746: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7747: /*   /\*   } *\/ */
                   7748: /*   /\* } *\/ */
1.126     brouard  7749: 
1.227     brouard  7750: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7751: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  7752:   
1.227     brouard  7753: /*   agelim=AGESUP; */
1.126     brouard  7754:   
1.227     brouard  7755: /*   hstepm=1; */
                   7756: /*   hstepm=hstepm/stepm;  */
1.218     brouard  7757:        
1.227     brouard  7758: /*   if (popforecast==1) { */
                   7759: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   7760: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   7761: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   7762: /*     }  */
                   7763: /*     popage=ivector(0,AGESUP); */
                   7764: /*     popeffectif=vector(0,AGESUP); */
                   7765: /*     popcount=vector(0,AGESUP); */
1.126     brouard  7766:     
1.227     brouard  7767: /*     i=1;    */
                   7768: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  7769:     
1.227     brouard  7770: /*     imx=i; */
                   7771: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   7772: /*   } */
1.218     brouard  7773:   
1.227     brouard  7774: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   7775: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   7776: /*       k=k+1; */
                   7777: /*       fprintf(ficrespop,"\n#******"); */
                   7778: /*       for(j=1;j<=cptcoveff;j++) { */
                   7779: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7780: /*       } */
                   7781: /*       fprintf(ficrespop,"******\n"); */
                   7782: /*       fprintf(ficrespop,"# Age"); */
                   7783: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   7784: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  7785:       
1.227     brouard  7786: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   7787: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  7788:        
1.227     brouard  7789: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7790: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7791: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7792:          
1.227     brouard  7793: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7794: /*       oldm=oldms;savm=savms; */
                   7795: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  7796:          
1.227     brouard  7797: /*       for (h=0; h<=nhstepm; h++){ */
                   7798: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7799: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7800: /*         }  */
                   7801: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7802: /*           kk1=0.;kk2=0; */
                   7803: /*           for(i=1; i<=nlstate;i++) {               */
                   7804: /*             if (mobilav==1)  */
                   7805: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   7806: /*             else { */
                   7807: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   7808: /*             } */
                   7809: /*           } */
                   7810: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   7811: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   7812: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   7813: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   7814: /*           } */
                   7815: /*         } */
                   7816: /*         for(i=1; i<=nlstate;i++){ */
                   7817: /*           kk1=0.; */
                   7818: /*           for(j=1; j<=nlstate;j++){ */
                   7819: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   7820: /*           } */
                   7821: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   7822: /*         } */
1.218     brouard  7823:            
1.227     brouard  7824: /*         if (h==(int)(calagedatem+12*cpt)) */
                   7825: /*           for(j=1; j<=nlstate;j++)  */
                   7826: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   7827: /*       } */
                   7828: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7829: /*     } */
                   7830: /*       } */
1.218     brouard  7831:       
1.227     brouard  7832: /*       /\******\/ */
1.218     brouard  7833:       
1.227     brouard  7834: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   7835: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   7836: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7837: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7838: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7839:          
1.227     brouard  7840: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7841: /*       oldm=oldms;savm=savms; */
                   7842: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   7843: /*       for (h=0; h<=nhstepm; h++){ */
                   7844: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7845: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7846: /*         }  */
                   7847: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7848: /*           kk1=0.;kk2=0; */
                   7849: /*           for(i=1; i<=nlstate;i++) {               */
                   7850: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   7851: /*           } */
                   7852: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   7853: /*         } */
                   7854: /*       } */
                   7855: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7856: /*     } */
                   7857: /*       } */
                   7858: /*     }  */
                   7859: /*   } */
1.218     brouard  7860:   
1.227     brouard  7861: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  7862:   
1.227     brouard  7863: /*   if (popforecast==1) { */
                   7864: /*     free_ivector(popage,0,AGESUP); */
                   7865: /*     free_vector(popeffectif,0,AGESUP); */
                   7866: /*     free_vector(popcount,0,AGESUP); */
                   7867: /*   } */
                   7868: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7869: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7870: /*   fclose(ficrespop); */
                   7871: /* } /\* End of popforecast *\/ */
1.218     brouard  7872:  
1.126     brouard  7873: int fileappend(FILE *fichier, char *optionfich)
                   7874: {
                   7875:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   7876:     printf("Problem with file: %s\n", optionfich);
                   7877:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   7878:     return (0);
                   7879:   }
                   7880:   fflush(fichier);
                   7881:   return (1);
                   7882: }
                   7883: 
                   7884: 
                   7885: /**************** function prwizard **********************/
                   7886: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   7887: {
                   7888: 
                   7889:   /* Wizard to print covariance matrix template */
                   7890: 
1.164     brouard  7891:   char ca[32], cb[32];
                   7892:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  7893:   int numlinepar;
                   7894: 
                   7895:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7896:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7897:   for(i=1; i <=nlstate; i++){
                   7898:     jj=0;
                   7899:     for(j=1; j <=nlstate+ndeath; j++){
                   7900:       if(j==i) continue;
                   7901:       jj++;
                   7902:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   7903:       printf("%1d%1d",i,j);
                   7904:       fprintf(ficparo,"%1d%1d",i,j);
                   7905:       for(k=1; k<=ncovmodel;k++){
                   7906:        /*        printf(" %lf",param[i][j][k]); */
                   7907:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   7908:        printf(" 0.");
                   7909:        fprintf(ficparo," 0.");
                   7910:       }
                   7911:       printf("\n");
                   7912:       fprintf(ficparo,"\n");
                   7913:     }
                   7914:   }
                   7915:   printf("# Scales (for hessian or gradient estimation)\n");
                   7916:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   7917:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   7918:   for(i=1; i <=nlstate; i++){
                   7919:     jj=0;
                   7920:     for(j=1; j <=nlstate+ndeath; j++){
                   7921:       if(j==i) continue;
                   7922:       jj++;
                   7923:       fprintf(ficparo,"%1d%1d",i,j);
                   7924:       printf("%1d%1d",i,j);
                   7925:       fflush(stdout);
                   7926:       for(k=1; k<=ncovmodel;k++){
                   7927:        /*      printf(" %le",delti3[i][j][k]); */
                   7928:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   7929:        printf(" 0.");
                   7930:        fprintf(ficparo," 0.");
                   7931:       }
                   7932:       numlinepar++;
                   7933:       printf("\n");
                   7934:       fprintf(ficparo,"\n");
                   7935:     }
                   7936:   }
                   7937:   printf("# Covariance matrix\n");
                   7938: /* # 121 Var(a12)\n\ */
                   7939: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7940: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   7941: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   7942: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   7943: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   7944: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   7945: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   7946:   fflush(stdout);
                   7947:   fprintf(ficparo,"# Covariance matrix\n");
                   7948:   /* # 121 Var(a12)\n\ */
                   7949:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7950:   /* #   ...\n\ */
                   7951:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   7952:   
                   7953:   for(itimes=1;itimes<=2;itimes++){
                   7954:     jj=0;
                   7955:     for(i=1; i <=nlstate; i++){
                   7956:       for(j=1; j <=nlstate+ndeath; j++){
                   7957:        if(j==i) continue;
                   7958:        for(k=1; k<=ncovmodel;k++){
                   7959:          jj++;
                   7960:          ca[0]= k+'a'-1;ca[1]='\0';
                   7961:          if(itimes==1){
                   7962:            printf("#%1d%1d%d",i,j,k);
                   7963:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   7964:          }else{
                   7965:            printf("%1d%1d%d",i,j,k);
                   7966:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   7967:            /*  printf(" %.5le",matcov[i][j]); */
                   7968:          }
                   7969:          ll=0;
                   7970:          for(li=1;li <=nlstate; li++){
                   7971:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   7972:              if(lj==li) continue;
                   7973:              for(lk=1;lk<=ncovmodel;lk++){
                   7974:                ll++;
                   7975:                if(ll<=jj){
                   7976:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   7977:                  if(ll<jj){
                   7978:                    if(itimes==1){
                   7979:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7980:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7981:                    }else{
                   7982:                      printf(" 0.");
                   7983:                      fprintf(ficparo," 0.");
                   7984:                    }
                   7985:                  }else{
                   7986:                    if(itimes==1){
                   7987:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   7988:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   7989:                    }else{
                   7990:                      printf(" 0.");
                   7991:                      fprintf(ficparo," 0.");
                   7992:                    }
                   7993:                  }
                   7994:                }
                   7995:              } /* end lk */
                   7996:            } /* end lj */
                   7997:          } /* end li */
                   7998:          printf("\n");
                   7999:          fprintf(ficparo,"\n");
                   8000:          numlinepar++;
                   8001:        } /* end k*/
                   8002:       } /*end j */
                   8003:     } /* end i */
                   8004:   } /* end itimes */
                   8005: 
                   8006: } /* end of prwizard */
                   8007: /******************* Gompertz Likelihood ******************************/
                   8008: double gompertz(double x[])
                   8009: { 
                   8010:   double A,B,L=0.0,sump=0.,num=0.;
                   8011:   int i,n=0; /* n is the size of the sample */
                   8012: 
1.220     brouard  8013:   for (i=1;i<=imx ; i++) {
1.126     brouard  8014:     sump=sump+weight[i];
                   8015:     /*    sump=sump+1;*/
                   8016:     num=num+1;
                   8017:   }
                   8018:  
                   8019:  
                   8020:   /* for (i=0; i<=imx; i++) 
                   8021:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8022: 
                   8023:   for (i=1;i<=imx ; i++)
                   8024:     {
                   8025:       if (cens[i] == 1 && wav[i]>1)
                   8026:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8027:       
                   8028:       if (cens[i] == 0 && wav[i]>1)
                   8029:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8030:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8031:       
                   8032:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8033:       if (wav[i] > 1 ) { /* ??? */
                   8034:        L=L+A*weight[i];
                   8035:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8036:       }
                   8037:     }
                   8038: 
                   8039:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8040:  
                   8041:   return -2*L*num/sump;
                   8042: }
                   8043: 
1.136     brouard  8044: #ifdef GSL
                   8045: /******************* Gompertz_f Likelihood ******************************/
                   8046: double gompertz_f(const gsl_vector *v, void *params)
                   8047: { 
                   8048:   double A,B,LL=0.0,sump=0.,num=0.;
                   8049:   double *x= (double *) v->data;
                   8050:   int i,n=0; /* n is the size of the sample */
                   8051: 
                   8052:   for (i=0;i<=imx-1 ; i++) {
                   8053:     sump=sump+weight[i];
                   8054:     /*    sump=sump+1;*/
                   8055:     num=num+1;
                   8056:   }
                   8057:  
                   8058:  
                   8059:   /* for (i=0; i<=imx; i++) 
                   8060:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8061:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   8062:   for (i=1;i<=imx ; i++)
                   8063:     {
                   8064:       if (cens[i] == 1 && wav[i]>1)
                   8065:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   8066:       
                   8067:       if (cens[i] == 0 && wav[i]>1)
                   8068:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   8069:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   8070:       
                   8071:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8072:       if (wav[i] > 1 ) { /* ??? */
                   8073:        LL=LL+A*weight[i];
                   8074:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8075:       }
                   8076:     }
                   8077: 
                   8078:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8079:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   8080:  
                   8081:   return -2*LL*num/sump;
                   8082: }
                   8083: #endif
                   8084: 
1.126     brouard  8085: /******************* Printing html file ***********/
1.201     brouard  8086: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  8087:                  int lastpass, int stepm, int weightopt, char model[],\
                   8088:                  int imx,  double p[],double **matcov,double agemortsup){
                   8089:   int i,k;
                   8090: 
                   8091:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   8092:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   8093:   for (i=1;i<=2;i++) 
                   8094:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  8095:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  8096:   fprintf(fichtm,"</ul>");
                   8097: 
                   8098: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   8099: 
                   8100:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   8101: 
                   8102:  for (k=agegomp;k<(agemortsup-2);k++) 
                   8103:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   8104: 
                   8105:  
                   8106:   fflush(fichtm);
                   8107: }
                   8108: 
                   8109: /******************* Gnuplot file **************/
1.201     brouard  8110: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  8111: 
                   8112:   char dirfileres[132],optfileres[132];
1.164     brouard  8113: 
1.126     brouard  8114:   int ng;
                   8115: 
                   8116: 
                   8117:   /*#ifdef windows */
                   8118:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   8119:     /*#endif */
                   8120: 
                   8121: 
                   8122:   strcpy(dirfileres,optionfilefiname);
                   8123:   strcpy(optfileres,"vpl");
1.199     brouard  8124:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  8125:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  8126:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  8127:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  8128:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   8129: 
                   8130: } 
                   8131: 
1.136     brouard  8132: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   8133: {
1.126     brouard  8134: 
1.136     brouard  8135:   /*-------- data file ----------*/
                   8136:   FILE *fic;
                   8137:   char dummy[]="                         ";
1.240     brouard  8138:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  8139:   int lstra;
1.136     brouard  8140:   int linei, month, year,iout;
                   8141:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  8142:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  8143:   char *stratrunc;
1.223     brouard  8144: 
1.240     brouard  8145:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   8146:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  8147: 
1.240     brouard  8148:   for(v=1; v <=ncovcol;v++){
                   8149:     DummyV[v]=0;
                   8150:     FixedV[v]=0;
                   8151:   }
                   8152:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   8153:     DummyV[v]=1;
                   8154:     FixedV[v]=0;
                   8155:   }
                   8156:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   8157:     DummyV[v]=0;
                   8158:     FixedV[v]=1;
                   8159:   }
                   8160:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8161:     DummyV[v]=1;
                   8162:     FixedV[v]=1;
                   8163:   }
                   8164:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8165:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8166:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8167:   }
1.126     brouard  8168: 
1.136     brouard  8169:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  8170:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   8171:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  8172:   }
1.126     brouard  8173: 
1.136     brouard  8174:   i=1;
                   8175:   linei=0;
                   8176:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   8177:     linei=linei+1;
                   8178:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   8179:       if(line[j] == '\t')
                   8180:        line[j] = ' ';
                   8181:     }
                   8182:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   8183:       ;
                   8184:     };
                   8185:     line[j+1]=0;  /* Trims blanks at end of line */
                   8186:     if(line[0]=='#'){
                   8187:       fprintf(ficlog,"Comment line\n%s\n",line);
                   8188:       printf("Comment line\n%s\n",line);
                   8189:       continue;
                   8190:     }
                   8191:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  8192:     strcpy(line, linetmp);
1.223     brouard  8193:     
                   8194:     /* Loops on waves */
                   8195:     for (j=maxwav;j>=1;j--){
                   8196:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  8197:        cutv(stra, strb, line, ' '); 
                   8198:        if(strb[0]=='.') { /* Missing value */
                   8199:          lval=-1;
                   8200:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   8201:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   8202:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   8203:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   8204:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   8205:            return 1;
                   8206:          }
                   8207:        }else{
                   8208:          errno=0;
                   8209:          /* what_kind_of_number(strb); */
                   8210:          dval=strtod(strb,&endptr); 
                   8211:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   8212:          /* if(strb != endptr && *endptr == '\0') */
                   8213:          /*    dval=dlval; */
                   8214:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8215:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8216:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   8217:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   8218:            return 1;
                   8219:          }
                   8220:          cotqvar[j][iv][i]=dval; 
                   8221:          cotvar[j][ntv+iv][i]=dval; 
                   8222:        }
                   8223:        strcpy(line,stra);
1.223     brouard  8224:       }/* end loop ntqv */
1.225     brouard  8225:       
1.223     brouard  8226:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  8227:        cutv(stra, strb, line, ' '); 
                   8228:        if(strb[0]=='.') { /* Missing value */
                   8229:          lval=-1;
                   8230:        }else{
                   8231:          errno=0;
                   8232:          lval=strtol(strb,&endptr,10); 
                   8233:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8234:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8235:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   8236:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   8237:            return 1;
                   8238:          }
                   8239:        }
                   8240:        if(lval <-1 || lval >1){
                   8241:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8242:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8243:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8244:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8245:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8246:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8247:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8248:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8249:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  8250:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8251:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8252:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8253:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8254:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8255:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8256:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8257:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8258:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  8259:          return 1;
                   8260:        }
                   8261:        cotvar[j][iv][i]=(double)(lval);
                   8262:        strcpy(line,stra);
1.223     brouard  8263:       }/* end loop ntv */
1.225     brouard  8264:       
1.223     brouard  8265:       /* Statuses  at wave */
1.137     brouard  8266:       cutv(stra, strb, line, ' '); 
1.223     brouard  8267:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  8268:        lval=-1;
1.136     brouard  8269:       }else{
1.238     brouard  8270:        errno=0;
                   8271:        lval=strtol(strb,&endptr,10); 
                   8272:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8273:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8274:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   8275:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   8276:          return 1;
                   8277:        }
1.136     brouard  8278:       }
1.225     brouard  8279:       
1.136     brouard  8280:       s[j][i]=lval;
1.225     brouard  8281:       
1.223     brouard  8282:       /* Date of Interview */
1.136     brouard  8283:       strcpy(line,stra);
                   8284:       cutv(stra, strb,line,' ');
1.169     brouard  8285:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8286:       }
1.169     brouard  8287:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  8288:        month=99;
                   8289:        year=9999;
1.136     brouard  8290:       }else{
1.225     brouard  8291:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   8292:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   8293:        return 1;
1.136     brouard  8294:       }
                   8295:       anint[j][i]= (double) year; 
                   8296:       mint[j][i]= (double)month; 
                   8297:       strcpy(line,stra);
1.223     brouard  8298:     } /* End loop on waves */
1.225     brouard  8299:     
1.223     brouard  8300:     /* Date of death */
1.136     brouard  8301:     cutv(stra, strb,line,' '); 
1.169     brouard  8302:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8303:     }
1.169     brouard  8304:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  8305:       month=99;
                   8306:       year=9999;
                   8307:     }else{
1.141     brouard  8308:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  8309:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   8310:       return 1;
1.136     brouard  8311:     }
                   8312:     andc[i]=(double) year; 
                   8313:     moisdc[i]=(double) month; 
                   8314:     strcpy(line,stra);
                   8315:     
1.223     brouard  8316:     /* Date of birth */
1.136     brouard  8317:     cutv(stra, strb,line,' '); 
1.169     brouard  8318:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8319:     }
1.169     brouard  8320:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  8321:       month=99;
                   8322:       year=9999;
                   8323:     }else{
1.141     brouard  8324:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   8325:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8326:       return 1;
1.136     brouard  8327:     }
                   8328:     if (year==9999) {
1.141     brouard  8329:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   8330:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8331:       return 1;
                   8332:       
1.136     brouard  8333:     }
                   8334:     annais[i]=(double)(year);
                   8335:     moisnais[i]=(double)(month); 
                   8336:     strcpy(line,stra);
1.225     brouard  8337:     
1.223     brouard  8338:     /* Sample weight */
1.136     brouard  8339:     cutv(stra, strb,line,' '); 
                   8340:     errno=0;
                   8341:     dval=strtod(strb,&endptr); 
                   8342:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  8343:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   8344:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  8345:       fflush(ficlog);
                   8346:       return 1;
                   8347:     }
                   8348:     weight[i]=dval; 
                   8349:     strcpy(line,stra);
1.225     brouard  8350:     
1.223     brouard  8351:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   8352:       cutv(stra, strb, line, ' '); 
                   8353:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  8354:        lval=-1;
1.223     brouard  8355:       }else{
1.225     brouard  8356:        errno=0;
                   8357:        /* what_kind_of_number(strb); */
                   8358:        dval=strtod(strb,&endptr);
                   8359:        /* if(strb != endptr && *endptr == '\0') */
                   8360:        /*   dval=dlval; */
                   8361:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8362:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8363:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   8364:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   8365:          return 1;
                   8366:        }
                   8367:        coqvar[iv][i]=dval; 
1.226     brouard  8368:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  8369:       }
                   8370:       strcpy(line,stra);
                   8371:     }/* end loop nqv */
1.136     brouard  8372:     
1.223     brouard  8373:     /* Covariate values */
1.136     brouard  8374:     for (j=ncovcol;j>=1;j--){
                   8375:       cutv(stra, strb,line,' '); 
1.223     brouard  8376:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  8377:        lval=-1;
1.136     brouard  8378:       }else{
1.225     brouard  8379:        errno=0;
                   8380:        lval=strtol(strb,&endptr,10); 
                   8381:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8382:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   8383:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   8384:          return 1;
                   8385:        }
1.136     brouard  8386:       }
                   8387:       if(lval <-1 || lval >1){
1.225     brouard  8388:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8389:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8390:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8391:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8392:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8393:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8394:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8395:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8396:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  8397:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8398:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8399:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8400:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8401:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8402:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8403:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8404:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8405:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  8406:        return 1;
1.136     brouard  8407:       }
                   8408:       covar[j][i]=(double)(lval);
                   8409:       strcpy(line,stra);
                   8410:     }  
                   8411:     lstra=strlen(stra);
1.225     brouard  8412:     
1.136     brouard  8413:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   8414:       stratrunc = &(stra[lstra-9]);
                   8415:       num[i]=atol(stratrunc);
                   8416:     }
                   8417:     else
                   8418:       num[i]=atol(stra);
                   8419:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   8420:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   8421:     
                   8422:     i=i+1;
                   8423:   } /* End loop reading  data */
1.225     brouard  8424:   
1.136     brouard  8425:   *imax=i-1; /* Number of individuals */
                   8426:   fclose(fic);
1.225     brouard  8427:   
1.136     brouard  8428:   return (0);
1.164     brouard  8429:   /* endread: */
1.225     brouard  8430:   printf("Exiting readdata: ");
                   8431:   fclose(fic);
                   8432:   return (1);
1.223     brouard  8433: }
1.126     brouard  8434: 
1.234     brouard  8435: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  8436:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  8437:   while (*p2 == ' ')
1.234     brouard  8438:     p2++; 
                   8439:   /* while ((*p1++ = *p2++) !=0) */
                   8440:   /*   ; */
                   8441:   /* do */
                   8442:   /*   while (*p2 == ' ') */
                   8443:   /*     p2++; */
                   8444:   /* while (*p1++ == *p2++); */
                   8445:   *stri=p2; 
1.145     brouard  8446: }
                   8447: 
1.235     brouard  8448: int decoderesult ( char resultline[], int nres)
1.230     brouard  8449: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   8450: {
1.235     brouard  8451:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  8452:   char resultsav[MAXLINE];
1.234     brouard  8453:   int resultmodel[MAXLINE];
                   8454:   int modelresult[MAXLINE];
1.230     brouard  8455:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   8456: 
1.234     brouard  8457:   removefirstspace(&resultline);
1.233     brouard  8458:   printf("decoderesult:%s\n",resultline);
1.230     brouard  8459: 
                   8460:   if (strstr(resultline,"v") !=0){
                   8461:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   8462:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   8463:     return 1;
                   8464:   }
                   8465:   trimbb(resultsav, resultline);
                   8466:   if (strlen(resultsav) >1){
                   8467:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   8468:   }
1.253     brouard  8469:   if(j == 0){ /* Resultline but no = */
                   8470:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   8471:     return (0);
                   8472:   }
                   8473:     
1.234     brouard  8474:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   8475:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8476:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8477:   }
                   8478:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   8479:     if(nbocc(resultsav,'=') >1){
                   8480:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   8481:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   8482:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   8483:     }else
                   8484:       cutl(strc,strd,resultsav,'=');
1.230     brouard  8485:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  8486:     
1.230     brouard  8487:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   8488:     Tvarsel[k]=atoi(strc);
                   8489:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   8490:     /* cptcovsel++;     */
                   8491:     if (nbocc(stra,'=') >0)
                   8492:       strcpy(resultsav,stra); /* and analyzes it */
                   8493:   }
1.235     brouard  8494:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  8495:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8496:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  8497:       match=0;
1.236     brouard  8498:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  8499:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  8500:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  8501:          match=1;
                   8502:          break;
                   8503:        }
                   8504:       }
                   8505:       if(match == 0){
                   8506:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8507:       }
                   8508:     }
                   8509:   }
1.235     brouard  8510:   /* Checking for missing or useless values in comparison of current model needs */
                   8511:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  8512:     match=0;
1.235     brouard  8513:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8514:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  8515:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  8516:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  8517:          ++match;
                   8518:        }
                   8519:       }
                   8520:     }
                   8521:     if(match == 0){
                   8522:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8523:     }else if(match > 1){
                   8524:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   8525:     }
                   8526:   }
1.235     brouard  8527:       
1.234     brouard  8528:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  8529:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8530:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   8531:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   8532:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   8533:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   8534:   /*    1 0 0 0 */
                   8535:   /*    2 1 0 0 */
                   8536:   /*    3 0 1 0 */ 
                   8537:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   8538:   /*    5 0 0 1 */
                   8539:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   8540:   /*    7 0 1 1 */
                   8541:   /*    8 1 1 1 */
1.237     brouard  8542:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   8543:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   8544:   /* V5*age V5 known which value for nres?  */
                   8545:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  8546:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   8547:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  8548:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  8549:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   8550:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  8551:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   8552:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   8553:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  8554:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   8555:       k4++;;
                   8556:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   8557:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   8558:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  8559:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   8560:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   8561:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  8562:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   8563:       k4q++;;
                   8564:     }
                   8565:   }
1.234     brouard  8566:   
1.235     brouard  8567:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  8568:   return (0);
                   8569: }
1.235     brouard  8570: 
1.230     brouard  8571: int decodemodel( char model[], int lastobs)
                   8572:  /**< This routine decodes the model and returns:
1.224     brouard  8573:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   8574:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   8575:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   8576:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   8577:        * - cptcovage number of covariates with age*products =2
                   8578:        * - cptcovs number of simple covariates
                   8579:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   8580:        *     which is a new column after the 9 (ncovcol) variables. 
                   8581:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   8582:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   8583:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   8584:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   8585:        */
1.136     brouard  8586: {
1.238     brouard  8587:   int i, j, k, ks, v;
1.227     brouard  8588:   int  j1, k1, k2, k3, k4;
1.136     brouard  8589:   char modelsav[80];
1.145     brouard  8590:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  8591:   char *strpt;
1.136     brouard  8592: 
1.145     brouard  8593:   /*removespace(model);*/
1.136     brouard  8594:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  8595:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  8596:     if (strstr(model,"AGE") !=0){
1.192     brouard  8597:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   8598:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  8599:       return 1;
                   8600:     }
1.141     brouard  8601:     if (strstr(model,"v") !=0){
                   8602:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   8603:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   8604:       return 1;
                   8605:     }
1.187     brouard  8606:     strcpy(modelsav,model); 
                   8607:     if ((strpt=strstr(model,"age*age")) !=0){
                   8608:       printf(" strpt=%s, model=%s\n",strpt, model);
                   8609:       if(strpt != model){
1.234     brouard  8610:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8611:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8612:  corresponding column of parameters.\n",model);
1.234     brouard  8613:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8614:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8615:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  8616:        return 1;
1.225     brouard  8617:       }
1.187     brouard  8618:       nagesqr=1;
                   8619:       if (strstr(model,"+age*age") !=0)
1.234     brouard  8620:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  8621:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  8622:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  8623:       else 
1.234     brouard  8624:        substrchaine(modelsav, model, "age*age");
1.187     brouard  8625:     }else
                   8626:       nagesqr=0;
                   8627:     if (strlen(modelsav) >1){
                   8628:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   8629:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  8630:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  8631:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  8632:                     * cst, age and age*age 
                   8633:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   8634:       /* including age products which are counted in cptcovage.
                   8635:        * but the covariates which are products must be treated 
                   8636:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  8637:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   8638:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  8639:       
                   8640:       
1.187     brouard  8641:       /*   Design
                   8642:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   8643:        *  <          ncovcol=8                >
                   8644:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   8645:        *   k=  1    2      3       4     5       6      7        8
                   8646:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   8647:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  8648:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   8649:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  8650:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   8651:        *  Tage[++cptcovage]=k
                   8652:        *       if products, new covar are created after ncovcol with k1
                   8653:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   8654:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   8655:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   8656:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   8657:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   8658:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   8659:        *  <          ncovcol=8                >
                   8660:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   8661:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   8662:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   8663:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8664:        * p Tprod[1]@2={                         6, 5}
                   8665:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   8666:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   8667:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   8668:        *How to reorganize?
                   8669:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   8670:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8671:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   8672:        * Struct []
                   8673:        */
1.225     brouard  8674:       
1.187     brouard  8675:       /* This loop fills the array Tvar from the string 'model'.*/
                   8676:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   8677:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   8678:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   8679:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   8680:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   8681:       /*       k=1 Tvar[1]=2 (from V2) */
                   8682:       /*       k=5 Tvar[5] */
                   8683:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  8684:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  8685:       /*       } */
1.198     brouard  8686:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  8687:       /*
                   8688:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  8689:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   8690:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   8691:       }
1.187     brouard  8692:       cptcovage=0;
                   8693:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  8694:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  8695:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  8696:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   8697:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   8698:        /*scanf("%d",i);*/
                   8699:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   8700:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   8701:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   8702:            /* covar is not filled and then is empty */
                   8703:            cptcovprod--;
                   8704:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   8705:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   8706:            Typevar[k]=1;  /* 1 for age product */
                   8707:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   8708:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   8709:            /*printf("stre=%s ", stre);*/
                   8710:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   8711:            cptcovprod--;
                   8712:            cutl(stre,strb,strc,'V');
                   8713:            Tvar[k]=atoi(stre);
                   8714:            Typevar[k]=1;  /* 1 for age product */
                   8715:            cptcovage++;
                   8716:            Tage[cptcovage]=k;
                   8717:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   8718:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   8719:            cptcovn++;
                   8720:            cptcovprodnoage++;k1++;
                   8721:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   8722:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   8723:                                                because this model-covariate is a construction we invent a new column
                   8724:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   8725:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   8726:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   8727:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   8728:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   8729:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   8730:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   8731:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   8732:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   8733:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   8734:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   8735:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  8736:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  8737:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   8738:            for (i=1; i<=lastobs;i++){
                   8739:              /* Computes the new covariate which is a product of
                   8740:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   8741:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   8742:            }
                   8743:          } /* End age is not in the model */
                   8744:        } /* End if model includes a product */
                   8745:        else { /* no more sum */
                   8746:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   8747:          /*  scanf("%d",i);*/
                   8748:          cutl(strd,strc,strb,'V');
                   8749:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   8750:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   8751:          Tvar[k]=atoi(strd);
                   8752:          Typevar[k]=0;  /* 0 for simple covariates */
                   8753:        }
                   8754:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  8755:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  8756:                                  scanf("%d",i);*/
1.187     brouard  8757:       } /* end of loop + on total covariates */
                   8758:     } /* end if strlen(modelsave == 0) age*age might exist */
                   8759:   } /* end if strlen(model == 0) */
1.136     brouard  8760:   
                   8761:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   8762:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  8763:   
1.136     brouard  8764:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  8765:      printf("cptcovprod=%d ", cptcovprod);
                   8766:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   8767:      scanf("%d ",i);*/
                   8768: 
                   8769: 
1.230     brouard  8770: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   8771:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  8772: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   8773:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   8774:    k =           1    2   3     4       5       6      7      8        9
                   8775:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   8776:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  8777:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   8778:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   8779:          Tmodelind[combination of covar]=k;
1.225     brouard  8780: */  
                   8781: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  8782:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  8783:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  8784:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  8785:   printf("Model=%s\n\
                   8786: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8787: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8788: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8789:   fprintf(ficlog,"Model=%s\n\
                   8790: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8791: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8792: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  8793:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  8794:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   8795:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  8796:       Fixed[k]= 0;
                   8797:       Dummy[k]= 0;
1.225     brouard  8798:       ncoveff++;
1.232     brouard  8799:       ncovf++;
1.234     brouard  8800:       nsd++;
                   8801:       modell[k].maintype= FTYPE;
                   8802:       TvarsD[nsd]=Tvar[k];
                   8803:       TvarsDind[nsd]=k;
                   8804:       TvarF[ncovf]=Tvar[k];
                   8805:       TvarFind[ncovf]=k;
                   8806:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8807:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8808:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   8809:       Fixed[k]= 0;
                   8810:       Dummy[k]= 0;
                   8811:       ncoveff++;
                   8812:       ncovf++;
                   8813:       modell[k].maintype= FTYPE;
                   8814:       TvarF[ncovf]=Tvar[k];
                   8815:       TvarFind[ncovf]=k;
1.230     brouard  8816:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  8817:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  8818:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  8819:       Fixed[k]= 0;
                   8820:       Dummy[k]= 1;
1.230     brouard  8821:       nqfveff++;
1.234     brouard  8822:       modell[k].maintype= FTYPE;
                   8823:       modell[k].subtype= FQ;
                   8824:       nsq++;
                   8825:       TvarsQ[nsq]=Tvar[k];
                   8826:       TvarsQind[nsq]=k;
1.232     brouard  8827:       ncovf++;
1.234     brouard  8828:       TvarF[ncovf]=Tvar[k];
                   8829:       TvarFind[ncovf]=k;
1.231     brouard  8830:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  8831:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  8832:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  8833:       Fixed[k]= 1;
                   8834:       Dummy[k]= 0;
1.225     brouard  8835:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  8836:       modell[k].maintype= VTYPE;
                   8837:       modell[k].subtype= VD;
                   8838:       nsd++;
                   8839:       TvarsD[nsd]=Tvar[k];
                   8840:       TvarsDind[nsd]=k;
                   8841:       ncovv++; /* Only simple time varying variables */
                   8842:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8843:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8844:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   8845:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  8846:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   8847:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  8848:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  8849:       Fixed[k]= 1;
                   8850:       Dummy[k]= 1;
                   8851:       nqtveff++;
                   8852:       modell[k].maintype= VTYPE;
                   8853:       modell[k].subtype= VQ;
                   8854:       ncovv++; /* Only simple time varying variables */
                   8855:       nsq++;
                   8856:       TvarsQ[nsq]=Tvar[k];
                   8857:       TvarsQind[nsq]=k;
                   8858:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8859:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8860:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   8861:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  8862:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   8863:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   8864:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  8865:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  8866:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  8867:       ncova++;
                   8868:       TvarA[ncova]=Tvar[k];
                   8869:       TvarAind[ncova]=k;
1.231     brouard  8870:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  8871:        Fixed[k]= 2;
                   8872:        Dummy[k]= 2;
                   8873:        modell[k].maintype= ATYPE;
                   8874:        modell[k].subtype= APFD;
                   8875:        /* ncoveff++; */
1.227     brouard  8876:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  8877:        Fixed[k]= 2;
                   8878:        Dummy[k]= 3;
                   8879:        modell[k].maintype= ATYPE;
                   8880:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   8881:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  8882:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  8883:        Fixed[k]= 3;
                   8884:        Dummy[k]= 2;
                   8885:        modell[k].maintype= ATYPE;
                   8886:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   8887:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  8888:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  8889:        Fixed[k]= 3;
                   8890:        Dummy[k]= 3;
                   8891:        modell[k].maintype= ATYPE;
                   8892:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   8893:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  8894:       }
                   8895:     }else if (Typevar[k] == 2) {  /* product without age */
                   8896:       k1=Tposprod[k];
                   8897:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  8898:        if(Tvard[k1][2] <=ncovcol){
                   8899:          Fixed[k]= 1;
                   8900:          Dummy[k]= 0;
                   8901:          modell[k].maintype= FTYPE;
                   8902:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   8903:          ncovf++; /* Fixed variables without age */
                   8904:          TvarF[ncovf]=Tvar[k];
                   8905:          TvarFind[ncovf]=k;
                   8906:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8907:          Fixed[k]= 0;  /* or 2 ?*/
                   8908:          Dummy[k]= 1;
                   8909:          modell[k].maintype= FTYPE;
                   8910:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   8911:          ncovf++; /* Varying variables without age */
                   8912:          TvarF[ncovf]=Tvar[k];
                   8913:          TvarFind[ncovf]=k;
                   8914:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8915:          Fixed[k]= 1;
                   8916:          Dummy[k]= 0;
                   8917:          modell[k].maintype= VTYPE;
                   8918:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   8919:          ncovv++; /* Varying variables without age */
                   8920:          TvarV[ncovv]=Tvar[k];
                   8921:          TvarVind[ncovv]=k;
                   8922:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8923:          Fixed[k]= 1;
                   8924:          Dummy[k]= 1;
                   8925:          modell[k].maintype= VTYPE;
                   8926:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   8927:          ncovv++; /* Varying variables without age */
                   8928:          TvarV[ncovv]=Tvar[k];
                   8929:          TvarVind[ncovv]=k;
                   8930:        }
1.227     brouard  8931:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  8932:        if(Tvard[k1][2] <=ncovcol){
                   8933:          Fixed[k]= 0;  /* or 2 ?*/
                   8934:          Dummy[k]= 1;
                   8935:          modell[k].maintype= FTYPE;
                   8936:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   8937:          ncovf++; /* Fixed variables without age */
                   8938:          TvarF[ncovf]=Tvar[k];
                   8939:          TvarFind[ncovf]=k;
                   8940:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8941:          Fixed[k]= 1;
                   8942:          Dummy[k]= 1;
                   8943:          modell[k].maintype= VTYPE;
                   8944:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   8945:          ncovv++; /* Varying variables without age */
                   8946:          TvarV[ncovv]=Tvar[k];
                   8947:          TvarVind[ncovv]=k;
                   8948:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8949:          Fixed[k]= 1;
                   8950:          Dummy[k]= 1;
                   8951:          modell[k].maintype= VTYPE;
                   8952:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   8953:          ncovv++; /* Varying variables without age */
                   8954:          TvarV[ncovv]=Tvar[k];
                   8955:          TvarVind[ncovv]=k;
                   8956:          ncovv++; /* Varying variables without age */
                   8957:          TvarV[ncovv]=Tvar[k];
                   8958:          TvarVind[ncovv]=k;
                   8959:        }
1.227     brouard  8960:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  8961:        if(Tvard[k1][2] <=ncovcol){
                   8962:          Fixed[k]= 1;
                   8963:          Dummy[k]= 1;
                   8964:          modell[k].maintype= VTYPE;
                   8965:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   8966:          ncovv++; /* Varying variables without age */
                   8967:          TvarV[ncovv]=Tvar[k];
                   8968:          TvarVind[ncovv]=k;
                   8969:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8970:          Fixed[k]= 1;
                   8971:          Dummy[k]= 1;
                   8972:          modell[k].maintype= VTYPE;
                   8973:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   8974:          ncovv++; /* Varying variables without age */
                   8975:          TvarV[ncovv]=Tvar[k];
                   8976:          TvarVind[ncovv]=k;
                   8977:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8978:          Fixed[k]= 1;
                   8979:          Dummy[k]= 0;
                   8980:          modell[k].maintype= VTYPE;
                   8981:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   8982:          ncovv++; /* Varying variables without age */
                   8983:          TvarV[ncovv]=Tvar[k];
                   8984:          TvarVind[ncovv]=k;
                   8985:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8986:          Fixed[k]= 1;
                   8987:          Dummy[k]= 1;
                   8988:          modell[k].maintype= VTYPE;
                   8989:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   8990:          ncovv++; /* Varying variables without age */
                   8991:          TvarV[ncovv]=Tvar[k];
                   8992:          TvarVind[ncovv]=k;
                   8993:        }
1.227     brouard  8994:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  8995:        if(Tvard[k1][2] <=ncovcol){
                   8996:          Fixed[k]= 1;
                   8997:          Dummy[k]= 1;
                   8998:          modell[k].maintype= VTYPE;
                   8999:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9000:          ncovv++; /* Varying variables without age */
                   9001:          TvarV[ncovv]=Tvar[k];
                   9002:          TvarVind[ncovv]=k;
                   9003:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9004:          Fixed[k]= 1;
                   9005:          Dummy[k]= 1;
                   9006:          modell[k].maintype= VTYPE;
                   9007:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9008:          ncovv++; /* Varying variables without age */
                   9009:          TvarV[ncovv]=Tvar[k];
                   9010:          TvarVind[ncovv]=k;
                   9011:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9012:          Fixed[k]= 1;
                   9013:          Dummy[k]= 1;
                   9014:          modell[k].maintype= VTYPE;
                   9015:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9016:          ncovv++; /* Varying variables without age */
                   9017:          TvarV[ncovv]=Tvar[k];
                   9018:          TvarVind[ncovv]=k;
                   9019:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9020:          Fixed[k]= 1;
                   9021:          Dummy[k]= 1;
                   9022:          modell[k].maintype= VTYPE;
                   9023:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9024:          ncovv++; /* Varying variables without age */
                   9025:          TvarV[ncovv]=Tvar[k];
                   9026:          TvarVind[ncovv]=k;
                   9027:        }
1.227     brouard  9028:       }else{
1.240     brouard  9029:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9030:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9031:       } /*end k1*/
1.225     brouard  9032:     }else{
1.226     brouard  9033:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9034:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9035:     }
1.227     brouard  9036:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9037:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9038:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9039:   }
                   9040:   /* Searching for doublons in the model */
                   9041:   for(k1=1; k1<= cptcovt;k1++){
                   9042:     for(k2=1; k2 <k1;k2++){
                   9043:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  9044:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9045:          if(Tvar[k1]==Tvar[k2]){
                   9046:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9047:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9048:            return(1);
                   9049:          }
                   9050:        }else if (Typevar[k1] ==2){
                   9051:          k3=Tposprod[k1];
                   9052:          k4=Tposprod[k2];
                   9053:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   9054:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9055:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9056:            return(1);
                   9057:          }
                   9058:        }
1.227     brouard  9059:       }
                   9060:     }
1.225     brouard  9061:   }
                   9062:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   9063:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  9064:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   9065:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  9066:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  9067:   /*endread:*/
1.225     brouard  9068:   printf("Exiting decodemodel: ");
                   9069:   return (1);
1.136     brouard  9070: }
                   9071: 
1.169     brouard  9072: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  9073: {/* Check ages at death */
1.136     brouard  9074:   int i, m;
1.218     brouard  9075:   int firstone=0;
                   9076:   
1.136     brouard  9077:   for (i=1; i<=imx; i++) {
                   9078:     for(m=2; (m<= maxwav); m++) {
                   9079:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   9080:        anint[m][i]=9999;
1.216     brouard  9081:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   9082:          s[m][i]=-1;
1.136     brouard  9083:       }
                   9084:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.169     brouard  9085:        *nberr = *nberr + 1;
1.218     brouard  9086:        if(firstone == 0){
                   9087:          firstone=1;
                   9088:        printf("Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\nOther similar cases in log file\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
                   9089:        }
                   9090:        fprintf(ficlog,"Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
1.136     brouard  9091:        s[m][i]=-1;
                   9092:       }
                   9093:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  9094:        (*nberr)++;
1.136     brouard  9095:        printf("Error! Month of death of individual %ld on line %d was unknown %2d, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,(int)moisdc[i]); 
                   9096:        fprintf(ficlog,"Error! Month of death of individual %ld on line %d was unknown %f, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,moisdc[i]); 
                   9097:        s[m][i]=-1; /* We prefer to skip it (and to skip it in version 0.8a1 too */
                   9098:       }
                   9099:     }
                   9100:   }
                   9101: 
                   9102:   for (i=1; i<=imx; i++)  {
                   9103:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   9104:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  9105:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  9106:        if (s[m][i] >= nlstate+1) {
1.169     brouard  9107:          if(agedc[i]>0){
                   9108:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  9109:              agev[m][i]=agedc[i];
1.214     brouard  9110:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  9111:            }else {
1.136     brouard  9112:              if ((int)andc[i]!=9999){
                   9113:                nbwarn++;
                   9114:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   9115:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   9116:                agev[m][i]=-1;
                   9117:              }
                   9118:            }
1.169     brouard  9119:          } /* agedc > 0 */
1.214     brouard  9120:        } /* end if */
1.136     brouard  9121:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   9122:                                 years but with the precision of a month */
                   9123:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   9124:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   9125:            agev[m][i]=1;
                   9126:          else if(agev[m][i] < *agemin){ 
                   9127:            *agemin=agev[m][i];
                   9128:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   9129:          }
                   9130:          else if(agev[m][i] >*agemax){
                   9131:            *agemax=agev[m][i];
1.156     brouard  9132:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  9133:          }
                   9134:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   9135:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  9136:        } /* en if 9*/
1.136     brouard  9137:        else { /* =9 */
1.214     brouard  9138:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  9139:          agev[m][i]=1;
                   9140:          s[m][i]=-1;
                   9141:        }
                   9142:       }
1.214     brouard  9143:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  9144:        agev[m][i]=1;
1.214     brouard  9145:       else{
                   9146:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9147:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9148:        agev[m][i]=0;
                   9149:       }
                   9150:     } /* End for lastpass */
                   9151:   }
1.136     brouard  9152:     
                   9153:   for (i=1; i<=imx; i++)  {
                   9154:     for(m=firstpass; (m<=lastpass); m++){
                   9155:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  9156:        (*nberr)++;
1.136     brouard  9157:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9158:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9159:        return 1;
                   9160:       }
                   9161:     }
                   9162:   }
                   9163: 
                   9164:   /*for (i=1; i<=imx; i++){
                   9165:   for (m=firstpass; (m<lastpass); m++){
                   9166:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   9167: }
                   9168: 
                   9169: }*/
                   9170: 
                   9171: 
1.139     brouard  9172:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   9173:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  9174: 
                   9175:   return (0);
1.164     brouard  9176:  /* endread:*/
1.136     brouard  9177:     printf("Exiting calandcheckages: ");
                   9178:     return (1);
                   9179: }
                   9180: 
1.172     brouard  9181: #if defined(_MSC_VER)
                   9182: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9183: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9184: //#include "stdafx.h"
                   9185: //#include <stdio.h>
                   9186: //#include <tchar.h>
                   9187: //#include <windows.h>
                   9188: //#include <iostream>
                   9189: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   9190: 
                   9191: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9192: 
                   9193: BOOL IsWow64()
                   9194: {
                   9195:        BOOL bIsWow64 = FALSE;
                   9196: 
                   9197:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   9198:        //  (HANDLE, PBOOL);
                   9199: 
                   9200:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9201: 
                   9202:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   9203:        const char funcName[] = "IsWow64Process";
                   9204:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   9205:                GetProcAddress(module, funcName);
                   9206: 
                   9207:        if (NULL != fnIsWow64Process)
                   9208:        {
                   9209:                if (!fnIsWow64Process(GetCurrentProcess(),
                   9210:                        &bIsWow64))
                   9211:                        //throw std::exception("Unknown error");
                   9212:                        printf("Unknown error\n");
                   9213:        }
                   9214:        return bIsWow64 != FALSE;
                   9215: }
                   9216: #endif
1.177     brouard  9217: 
1.191     brouard  9218: void syscompilerinfo(int logged)
1.167     brouard  9219:  {
                   9220:    /* #include "syscompilerinfo.h"*/
1.185     brouard  9221:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   9222:    /* /GS /W3 /Gy
                   9223:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   9224:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   9225:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  9226:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   9227:    */ 
                   9228:    /* 64 bits */
1.185     brouard  9229:    /*
                   9230:      /GS /W3 /Gy
                   9231:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   9232:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   9233:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   9234:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   9235:    /* Optimization are useless and O3 is slower than O2 */
                   9236:    /*
                   9237:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   9238:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   9239:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   9240:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   9241:    */
1.186     brouard  9242:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  9243:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   9244:       /PDB:"visual studio
                   9245:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   9246:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   9247:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   9248:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   9249:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   9250:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   9251:       uiAccess='false'"
                   9252:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   9253:       /NOLOGO /TLBID:1
                   9254:    */
1.177     brouard  9255: #if defined __INTEL_COMPILER
1.178     brouard  9256: #if defined(__GNUC__)
                   9257:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   9258: #endif
1.177     brouard  9259: #elif defined(__GNUC__) 
1.179     brouard  9260: #ifndef  __APPLE__
1.174     brouard  9261: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  9262: #endif
1.177     brouard  9263:    struct utsname sysInfo;
1.178     brouard  9264:    int cross = CROSS;
                   9265:    if (cross){
                   9266:           printf("Cross-");
1.191     brouard  9267:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  9268:    }
1.174     brouard  9269: #endif
                   9270: 
1.171     brouard  9271: #include <stdint.h>
1.178     brouard  9272: 
1.191     brouard  9273:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  9274: #if defined(__clang__)
1.191     brouard  9275:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  9276: #endif
                   9277: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  9278:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  9279: #endif
                   9280: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  9281:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  9282: #endif
                   9283: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  9284:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  9285: #endif
                   9286: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  9287:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  9288: #endif
                   9289: #if defined(_MSC_VER)
1.191     brouard  9290:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  9291: #endif
                   9292: #if defined(__PGI)
1.191     brouard  9293:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  9294: #endif
                   9295: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  9296:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  9297: #endif
1.191     brouard  9298:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  9299:    
1.167     brouard  9300: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   9301: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   9302:     // Windows (x64 and x86)
1.191     brouard  9303:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  9304: #elif __unix__ // all unices, not all compilers
                   9305:     // Unix
1.191     brouard  9306:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  9307: #elif __linux__
                   9308:     // linux
1.191     brouard  9309:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  9310: #elif __APPLE__
1.174     brouard  9311:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  9312:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  9313: #endif
                   9314: 
                   9315: /*  __MINGW32__          */
                   9316: /*  __CYGWIN__  */
                   9317: /* __MINGW64__  */
                   9318: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   9319: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   9320: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   9321: /* _WIN64  // Defined for applications for Win64. */
                   9322: /* _M_X64 // Defined for compilations that target x64 processors. */
                   9323: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  9324: 
1.167     brouard  9325: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  9326:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  9327: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  9328:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  9329: #else
1.191     brouard  9330:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  9331: #endif
                   9332: 
1.169     brouard  9333: #if defined(__GNUC__)
                   9334: # if defined(__GNUC_PATCHLEVEL__)
                   9335: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9336:                             + __GNUC_MINOR__ * 100 \
                   9337:                             + __GNUC_PATCHLEVEL__)
                   9338: # else
                   9339: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9340:                             + __GNUC_MINOR__ * 100)
                   9341: # endif
1.174     brouard  9342:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  9343:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  9344: 
                   9345:    if (uname(&sysInfo) != -1) {
                   9346:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  9347:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  9348:    }
                   9349:    else
                   9350:       perror("uname() error");
1.179     brouard  9351:    //#ifndef __INTEL_COMPILER 
                   9352: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  9353:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  9354:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  9355: #endif
1.169     brouard  9356: #endif
1.172     brouard  9357: 
                   9358:    //   void main()
                   9359:    //   {
1.169     brouard  9360: #if defined(_MSC_VER)
1.174     brouard  9361:    if (IsWow64()){
1.191     brouard  9362:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   9363:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  9364:    }
                   9365:    else{
1.191     brouard  9366:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   9367:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  9368:    }
1.172     brouard  9369:    //     printf("\nPress Enter to continue...");
                   9370:    //     getchar();
                   9371:    //   }
                   9372: 
1.169     brouard  9373: #endif
                   9374:    
1.167     brouard  9375: 
1.219     brouard  9376: }
1.136     brouard  9377: 
1.219     brouard  9378: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  9379:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  9380:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  9381:   /* double ftolpl = 1.e-10; */
1.180     brouard  9382:   double age, agebase, agelim;
1.203     brouard  9383:   double tot;
1.180     brouard  9384: 
1.202     brouard  9385:   strcpy(filerespl,"PL_");
                   9386:   strcat(filerespl,fileresu);
                   9387:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   9388:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9389:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9390:   }
1.227     brouard  9391:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   9392:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  9393:   pstamp(ficrespl);
1.203     brouard  9394:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  9395:   fprintf(ficrespl,"#Age ");
                   9396:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   9397:   fprintf(ficrespl,"\n");
1.180     brouard  9398:   
1.219     brouard  9399:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  9400: 
1.219     brouard  9401:   agebase=ageminpar;
                   9402:   agelim=agemaxpar;
1.180     brouard  9403: 
1.227     brouard  9404:   /* i1=pow(2,ncoveff); */
1.234     brouard  9405:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  9406:   if (cptcovn < 1){i1=1;}
1.180     brouard  9407: 
1.238     brouard  9408:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   9409:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  9410:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9411:        continue;
1.235     brouard  9412: 
1.238     brouard  9413:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9414:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   9415:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   9416:       /* k=k+1; */
                   9417:       /* to clean */
                   9418:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9419:       fprintf(ficrespl,"#******");
                   9420:       printf("#******");
                   9421:       fprintf(ficlog,"#******");
                   9422:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9423:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   9424:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9425:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9426:       }
                   9427:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9428:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9429:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9430:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9431:       }
                   9432:       fprintf(ficrespl,"******\n");
                   9433:       printf("******\n");
                   9434:       fprintf(ficlog,"******\n");
                   9435:       if(invalidvarcomb[k]){
                   9436:        printf("\nCombination (%d) ignored because no case \n",k); 
                   9437:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   9438:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   9439:        continue;
                   9440:       }
1.219     brouard  9441: 
1.238     brouard  9442:       fprintf(ficrespl,"#Age ");
                   9443:       for(j=1;j<=cptcoveff;j++) {
                   9444:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9445:       }
                   9446:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   9447:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  9448:     
1.238     brouard  9449:       for (age=agebase; age<=agelim; age++){
                   9450:        /* for (age=agebase; age<=agebase; age++){ */
                   9451:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   9452:        fprintf(ficrespl,"%.0f ",age );
                   9453:        for(j=1;j<=cptcoveff;j++)
                   9454:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9455:        tot=0.;
                   9456:        for(i=1; i<=nlstate;i++){
                   9457:          tot +=  prlim[i][i];
                   9458:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   9459:        }
                   9460:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   9461:       } /* Age */
                   9462:       /* was end of cptcod */
                   9463:     } /* cptcov */
                   9464:   } /* nres */
1.219     brouard  9465:   return 0;
1.180     brouard  9466: }
                   9467: 
1.218     brouard  9468: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   9469:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   9470:        
                   9471:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   9472:    * at any age between ageminpar and agemaxpar
                   9473:         */
1.235     brouard  9474:   int i, j, k, i1, nres=0 ;
1.217     brouard  9475:   /* double ftolpl = 1.e-10; */
                   9476:   double age, agebase, agelim;
                   9477:   double tot;
1.218     brouard  9478:   /* double ***mobaverage; */
                   9479:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  9480: 
                   9481:   strcpy(fileresplb,"PLB_");
                   9482:   strcat(fileresplb,fileresu);
                   9483:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   9484:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9485:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9486:   }
                   9487:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9488:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9489:   pstamp(ficresplb);
                   9490:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   9491:   fprintf(ficresplb,"#Age ");
                   9492:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   9493:   fprintf(ficresplb,"\n");
                   9494:   
1.218     brouard  9495:   
                   9496:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   9497:   
                   9498:   agebase=ageminpar;
                   9499:   agelim=agemaxpar;
                   9500:   
                   9501:   
1.227     brouard  9502:   i1=pow(2,cptcoveff);
1.218     brouard  9503:   if (cptcovn < 1){i1=1;}
1.227     brouard  9504:   
1.238     brouard  9505:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9506:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  9507:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9508:        continue;
                   9509:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9510:       fprintf(ficresplb,"#******");
                   9511:       printf("#******");
                   9512:       fprintf(ficlog,"#******");
                   9513:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9514:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9515:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9516:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9517:       }
                   9518:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9519:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9520:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9521:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9522:       }
                   9523:       fprintf(ficresplb,"******\n");
                   9524:       printf("******\n");
                   9525:       fprintf(ficlog,"******\n");
                   9526:       if(invalidvarcomb[k]){
                   9527:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   9528:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   9529:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   9530:        continue;
                   9531:       }
1.218     brouard  9532:     
1.238     brouard  9533:       fprintf(ficresplb,"#Age ");
                   9534:       for(j=1;j<=cptcoveff;j++) {
                   9535:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9536:       }
                   9537:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   9538:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  9539:     
                   9540:     
1.238     brouard  9541:       for (age=agebase; age<=agelim; age++){
                   9542:        /* for (age=agebase; age<=agebase; age++){ */
                   9543:        if(mobilavproj > 0){
                   9544:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   9545:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9546:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  9547:        }else if (mobilavproj == 0){
                   9548:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9549:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9550:          exit(1);
                   9551:        }else{
                   9552:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9553:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.238     brouard  9554:        }
                   9555:        fprintf(ficresplb,"%.0f ",age );
                   9556:        for(j=1;j<=cptcoveff;j++)
                   9557:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9558:        tot=0.;
                   9559:        for(i=1; i<=nlstate;i++){
                   9560:          tot +=  bprlim[i][i];
                   9561:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   9562:        }
                   9563:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   9564:       } /* Age */
                   9565:       /* was end of cptcod */
                   9566:     } /* end of any combination */
                   9567:   } /* end of nres */  
1.218     brouard  9568:   /* hBijx(p, bage, fage); */
                   9569:   /* fclose(ficrespijb); */
                   9570:   
                   9571:   return 0;
1.217     brouard  9572: }
1.218     brouard  9573:  
1.180     brouard  9574: int hPijx(double *p, int bage, int fage){
                   9575:     /*------------- h Pij x at various ages ------------*/
                   9576: 
                   9577:   int stepsize;
                   9578:   int agelim;
                   9579:   int hstepm;
                   9580:   int nhstepm;
1.235     brouard  9581:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  9582: 
                   9583:   double agedeb;
                   9584:   double ***p3mat;
                   9585: 
1.201     brouard  9586:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  9587:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   9588:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9589:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9590:     }
                   9591:     printf("Computing pij: result on file '%s' \n", filerespij);
                   9592:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   9593:   
                   9594:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9595:     /*if (stepm<=24) stepsize=2;*/
                   9596: 
                   9597:     agelim=AGESUP;
                   9598:     hstepm=stepsize*YEARM; /* Every year of age */
                   9599:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  9600:                
1.180     brouard  9601:     /* hstepm=1;   aff par mois*/
                   9602:     pstamp(ficrespij);
                   9603:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  9604:     i1= pow(2,cptcoveff);
1.218     brouard  9605:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9606:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9607:                /*      k=k+1;  */
1.235     brouard  9608:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9609:     for(k=1; k<=i1;k++){
1.253     brouard  9610:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  9611:        continue;
1.183     brouard  9612:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  9613:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  9614:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  9615:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9616:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9617:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9618:       }
1.183     brouard  9619:       fprintf(ficrespij,"******\n");
                   9620:       
                   9621:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   9622:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   9623:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   9624:        
                   9625:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  9626:        
1.183     brouard  9627:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9628:        oldm=oldms;savm=savms;
1.235     brouard  9629:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  9630:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   9631:        for(i=1; i<=nlstate;i++)
                   9632:          for(j=1; j<=nlstate+ndeath;j++)
                   9633:            fprintf(ficrespij," %1d-%1d",i,j);
                   9634:        fprintf(ficrespij,"\n");
                   9635:        for (h=0; h<=nhstepm; h++){
                   9636:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9637:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  9638:          for(i=1; i<=nlstate;i++)
                   9639:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  9640:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  9641:          fprintf(ficrespij,"\n");
                   9642:        }
1.183     brouard  9643:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9644:        fprintf(ficrespij,"\n");
                   9645:       }
1.180     brouard  9646:       /*}*/
                   9647:     }
1.218     brouard  9648:     return 0;
1.180     brouard  9649: }
1.218     brouard  9650:  
                   9651:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  9652:     /*------------- h Bij x at various ages ------------*/
                   9653: 
                   9654:   int stepsize;
1.218     brouard  9655:   /* int agelim; */
                   9656:        int ageminl;
1.217     brouard  9657:   int hstepm;
                   9658:   int nhstepm;
1.238     brouard  9659:   int h, i, i1, j, k, nres;
1.218     brouard  9660:        
1.217     brouard  9661:   double agedeb;
                   9662:   double ***p3mat;
1.218     brouard  9663:        
                   9664:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   9665:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   9666:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9667:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9668:   }
                   9669:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   9670:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   9671:   
                   9672:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9673:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  9674:   
1.218     brouard  9675:   /* agelim=AGESUP; */
                   9676:   ageminl=30;
                   9677:   hstepm=stepsize*YEARM; /* Every year of age */
                   9678:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   9679:   
                   9680:   /* hstepm=1;   aff par mois*/
                   9681:   pstamp(ficrespijb);
                   9682:   fprintf(ficrespijb,"#****** h Pij x Back Probability to be in state i at age x-h being in j at x ");
1.227     brouard  9683:   i1= pow(2,cptcoveff);
1.218     brouard  9684:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9685:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9686:   /*   k=k+1;  */
1.238     brouard  9687:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9688:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  9689:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9690:        continue;
                   9691:       fprintf(ficrespijb,"\n#****** ");
                   9692:       for(j=1;j<=cptcoveff;j++)
                   9693:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9694:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9695:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9696:       }
                   9697:       fprintf(ficrespijb,"******\n");
                   9698:       if(invalidvarcomb[k]){
                   9699:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   9700:        continue;
                   9701:       }
                   9702:       
                   9703:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   9704:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   9705:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   9706:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   9707:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   9708:        
                   9709:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   9710:        
                   9711:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9712:        /* oldm=oldms;savm=savms; */
                   9713:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9714:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k);
                   9715:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
                   9716:        fprintf(ficrespijb,"# Cov Agex agex-h hpijx with i,j=");
1.217     brouard  9717:        for(i=1; i<=nlstate;i++)
                   9718:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  9719:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  9720:        fprintf(ficrespijb,"\n");
1.238     brouard  9721:        for (h=0; h<=nhstepm; h++){
                   9722:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9723:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   9724:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   9725:          for(i=1; i<=nlstate;i++)
                   9726:            for(j=1; j<=nlstate+ndeath;j++)
                   9727:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   9728:          fprintf(ficrespijb,"\n");
                   9729:        }
                   9730:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9731:        fprintf(ficrespijb,"\n");
                   9732:       } /* end age deb */
                   9733:     } /* end combination */
                   9734:   } /* end nres */
1.218     brouard  9735:   return 0;
                   9736:  } /*  hBijx */
1.217     brouard  9737: 
1.180     brouard  9738: 
1.136     brouard  9739: /***********************************************/
                   9740: /**************** Main Program *****************/
                   9741: /***********************************************/
                   9742: 
                   9743: int main(int argc, char *argv[])
                   9744: {
                   9745: #ifdef GSL
                   9746:   const gsl_multimin_fminimizer_type *T;
                   9747:   size_t iteri = 0, it;
                   9748:   int rval = GSL_CONTINUE;
                   9749:   int status = GSL_SUCCESS;
                   9750:   double ssval;
                   9751: #endif
                   9752:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  9753:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  9754:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  9755:   int jj, ll, li, lj, lk;
1.136     brouard  9756:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  9757:   int num_filled;
1.136     brouard  9758:   int itimes;
                   9759:   int NDIM=2;
                   9760:   int vpopbased=0;
1.235     brouard  9761:   int nres=0;
1.136     brouard  9762: 
1.164     brouard  9763:   char ca[32], cb[32];
1.136     brouard  9764:   /*  FILE *fichtm; *//* Html File */
                   9765:   /* FILE *ficgp;*/ /*Gnuplot File */
                   9766:   struct stat info;
1.191     brouard  9767:   double agedeb=0.;
1.194     brouard  9768: 
                   9769:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  9770:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  9771: 
1.165     brouard  9772:   double fret;
1.191     brouard  9773:   double dum=0.; /* Dummy variable */
1.136     brouard  9774:   double ***p3mat;
1.218     brouard  9775:   /* double ***mobaverage; */
1.164     brouard  9776: 
                   9777:   char line[MAXLINE];
1.197     brouard  9778:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   9779: 
1.234     brouard  9780:   char  modeltemp[MAXLINE];
1.230     brouard  9781:   char resultline[MAXLINE];
                   9782:   
1.136     brouard  9783:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  9784:   char *tok, *val; /* pathtot */
1.136     brouard  9785:   int firstobs=1, lastobs=10;
1.195     brouard  9786:   int c,  h , cpt, c2;
1.191     brouard  9787:   int jl=0;
                   9788:   int i1, j1, jk, stepsize=0;
1.194     brouard  9789:   int count=0;
                   9790: 
1.164     brouard  9791:   int *tab; 
1.136     brouard  9792:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  9793:   int backcast=0;
1.136     brouard  9794:   int mobilav=0,popforecast=0;
1.191     brouard  9795:   int hstepm=0, nhstepm=0;
1.136     brouard  9796:   int agemortsup;
                   9797:   float  sumlpop=0.;
                   9798:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   9799:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   9800: 
1.191     brouard  9801:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  9802:   double ftolpl=FTOL;
                   9803:   double **prlim;
1.217     brouard  9804:   double **bprlim;
1.136     brouard  9805:   double ***param; /* Matrix of parameters */
1.251     brouard  9806:   double ***paramstart; /* Matrix of starting parameter values */
                   9807:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  9808:   double **matcov; /* Matrix of covariance */
1.203     brouard  9809:   double **hess; /* Hessian matrix */
1.136     brouard  9810:   double ***delti3; /* Scale */
                   9811:   double *delti; /* Scale */
                   9812:   double ***eij, ***vareij;
                   9813:   double **varpl; /* Variances of prevalence limits by age */
                   9814:   double *epj, vepp;
1.164     brouard  9815: 
1.136     brouard  9816:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  9817:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   9818: 
1.136     brouard  9819:   double **ximort;
1.145     brouard  9820:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  9821:   int *dcwave;
                   9822: 
1.164     brouard  9823:   char z[1]="c";
1.136     brouard  9824: 
                   9825:   /*char  *strt;*/
                   9826:   char strtend[80];
1.126     brouard  9827: 
1.164     brouard  9828: 
1.126     brouard  9829: /*   setlocale (LC_ALL, ""); */
                   9830: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   9831: /*   textdomain (PACKAGE); */
                   9832: /*   setlocale (LC_CTYPE, ""); */
                   9833: /*   setlocale (LC_MESSAGES, ""); */
                   9834: 
                   9835:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  9836:   rstart_time = time(NULL);  
                   9837:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   9838:   start_time = *localtime(&rstart_time);
1.126     brouard  9839:   curr_time=start_time;
1.157     brouard  9840:   /*tml = *localtime(&start_time.tm_sec);*/
                   9841:   /* strcpy(strstart,asctime(&tml)); */
                   9842:   strcpy(strstart,asctime(&start_time));
1.126     brouard  9843: 
                   9844: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  9845: /*  tp.tm_sec = tp.tm_sec +86400; */
                   9846: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  9847: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   9848: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   9849: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  9850: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  9851: /*   strt=asctime(&tmg); */
                   9852: /*   printf("Time(after) =%s",strstart);  */
                   9853: /*  (void) time (&time_value);
                   9854: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   9855: *  tm = *localtime(&time_value);
                   9856: *  strstart=asctime(&tm);
                   9857: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   9858: */
                   9859: 
                   9860:   nberr=0; /* Number of errors and warnings */
                   9861:   nbwarn=0;
1.184     brouard  9862: #ifdef WIN32
                   9863:   _getcwd(pathcd, size);
                   9864: #else
1.126     brouard  9865:   getcwd(pathcd, size);
1.184     brouard  9866: #endif
1.191     brouard  9867:   syscompilerinfo(0);
1.196     brouard  9868:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  9869:   if(argc <=1){
                   9870:     printf("\nEnter the parameter file name: ");
1.205     brouard  9871:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   9872:       printf("ERROR Empty parameter file name\n");
                   9873:       goto end;
                   9874:     }
1.126     brouard  9875:     i=strlen(pathr);
                   9876:     if(pathr[i-1]=='\n')
                   9877:       pathr[i-1]='\0';
1.156     brouard  9878:     i=strlen(pathr);
1.205     brouard  9879:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  9880:       pathr[i-1]='\0';
1.205     brouard  9881:     }
                   9882:     i=strlen(pathr);
                   9883:     if( i==0 ){
                   9884:       printf("ERROR Empty parameter file name\n");
                   9885:       goto end;
                   9886:     }
                   9887:     for (tok = pathr; tok != NULL; ){
1.126     brouard  9888:       printf("Pathr |%s|\n",pathr);
                   9889:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   9890:       printf("val= |%s| pathr=%s\n",val,pathr);
                   9891:       strcpy (pathtot, val);
                   9892:       if(pathr[0] == '\0') break; /* Dirty */
                   9893:     }
                   9894:   }
                   9895:   else{
                   9896:     strcpy(pathtot,argv[1]);
                   9897:   }
                   9898:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   9899:   /*cygwin_split_path(pathtot,path,optionfile);
                   9900:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   9901:   /* cutv(path,optionfile,pathtot,'\\');*/
                   9902: 
                   9903:   /* Split argv[0], imach program to get pathimach */
                   9904:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   9905:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9906:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9907:  /*   strcpy(pathimach,argv[0]); */
                   9908:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   9909:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   9910:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  9911: #ifdef WIN32
                   9912:   _chdir(path); /* Can be a relative path */
                   9913:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   9914: #else
1.126     brouard  9915:   chdir(path); /* Can be a relative path */
1.184     brouard  9916:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   9917: #endif
                   9918:   printf("Current directory %s!\n",pathcd);
1.126     brouard  9919:   strcpy(command,"mkdir ");
                   9920:   strcat(command,optionfilefiname);
                   9921:   if((outcmd=system(command)) != 0){
1.169     brouard  9922:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  9923:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   9924:     /* fclose(ficlog); */
                   9925: /*     exit(1); */
                   9926:   }
                   9927: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   9928: /*     perror("mkdir"); */
                   9929: /*   } */
                   9930: 
                   9931:   /*-------- arguments in the command line --------*/
                   9932: 
1.186     brouard  9933:   /* Main Log file */
1.126     brouard  9934:   strcat(filelog, optionfilefiname);
                   9935:   strcat(filelog,".log");    /* */
                   9936:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   9937:     printf("Problem with logfile %s\n",filelog);
                   9938:     goto end;
                   9939:   }
                   9940:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  9941:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  9942:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   9943:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   9944:  path=%s \n\
                   9945:  optionfile=%s\n\
                   9946:  optionfilext=%s\n\
1.156     brouard  9947:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  9948: 
1.197     brouard  9949:   syscompilerinfo(1);
1.167     brouard  9950: 
1.126     brouard  9951:   printf("Local time (at start):%s",strstart);
                   9952:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   9953:   fflush(ficlog);
                   9954: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  9955: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  9956: 
                   9957:   /* */
                   9958:   strcpy(fileres,"r");
                   9959:   strcat(fileres, optionfilefiname);
1.201     brouard  9960:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  9961:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  9962:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  9963: 
1.186     brouard  9964:   /* Main ---------arguments file --------*/
1.126     brouard  9965: 
                   9966:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  9967:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   9968:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  9969:     fflush(ficlog);
1.149     brouard  9970:     /* goto end; */
                   9971:     exit(70); 
1.126     brouard  9972:   }
                   9973: 
                   9974: 
                   9975: 
                   9976:   strcpy(filereso,"o");
1.201     brouard  9977:   strcat(filereso,fileresu);
1.126     brouard  9978:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   9979:     printf("Problem with Output resultfile: %s\n", filereso);
                   9980:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   9981:     fflush(ficlog);
                   9982:     goto end;
                   9983:   }
                   9984: 
                   9985:   /* Reads comments: lines beginning with '#' */
                   9986:   numlinepar=0;
1.197     brouard  9987: 
                   9988:     /* First parameter line */
                   9989:   while(fgets(line, MAXLINE, ficpar)) {
                   9990:     /* If line starts with a # it is a comment */
                   9991:     if (line[0] == '#') {
                   9992:       numlinepar++;
                   9993:       fputs(line,stdout);
                   9994:       fputs(line,ficparo);
                   9995:       fputs(line,ficlog);
                   9996:       continue;
                   9997:     }else
                   9998:       break;
                   9999:   }
                   10000:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   10001:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   10002:     if (num_filled != 5) {
                   10003:       printf("Should be 5 parameters\n");
                   10004:     }
1.126     brouard  10005:     numlinepar++;
1.197     brouard  10006:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   10007:   }
                   10008:   /* Second parameter line */
                   10009:   while(fgets(line, MAXLINE, ficpar)) {
                   10010:     /* If line starts with a # it is a comment */
                   10011:     if (line[0] == '#') {
                   10012:       numlinepar++;
                   10013:       fputs(line,stdout);
                   10014:       fputs(line,ficparo);
                   10015:       fputs(line,ficlog);
                   10016:       continue;
                   10017:     }else
                   10018:       break;
                   10019:   }
1.223     brouard  10020:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   10021:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   10022:     if (num_filled != 11) {
                   10023:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  10024:       printf("but line=%s\n",line);
1.197     brouard  10025:     }
1.223     brouard  10026:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  10027:   }
1.203     brouard  10028:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  10029:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  10030:   /* Third parameter line */
                   10031:   while(fgets(line, MAXLINE, ficpar)) {
                   10032:     /* If line starts with a # it is a comment */
                   10033:     if (line[0] == '#') {
                   10034:       numlinepar++;
                   10035:       fputs(line,stdout);
                   10036:       fputs(line,ficparo);
                   10037:       fputs(line,ficlog);
                   10038:       continue;
                   10039:     }else
                   10040:       break;
                   10041:   }
1.201     brouard  10042:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
                   10043:     if (num_filled == 0)
                   10044:             model[0]='\0';
                   10045:     else if (num_filled != 1){
1.197     brouard  10046:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10047:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10048:       model[0]='\0';
                   10049:       goto end;
                   10050:     }
                   10051:     else{
                   10052:       if (model[0]=='+'){
                   10053:        for(i=1; i<=strlen(model);i++)
                   10054:          modeltemp[i-1]=model[i];
1.201     brouard  10055:        strcpy(model,modeltemp); 
1.197     brouard  10056:       }
                   10057:     }
1.199     brouard  10058:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  10059:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  10060:   }
                   10061:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   10062:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   10063:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  10064:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   10065:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  10066:   fflush(ficlog);
1.190     brouard  10067:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   10068:   if(model[0]=='#'){
1.187     brouard  10069:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   10070:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   10071:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   10072:     if(mle != -1){
                   10073:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   10074:       exit(1);
                   10075:     }
                   10076:   }
1.126     brouard  10077:   while((c=getc(ficpar))=='#' && c!= EOF){
                   10078:     ungetc(c,ficpar);
                   10079:     fgets(line, MAXLINE, ficpar);
                   10080:     numlinepar++;
1.195     brouard  10081:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   10082:       z[0]=line[1];
                   10083:     }
                   10084:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  10085:     fputs(line, stdout);
                   10086:     //puts(line);
1.126     brouard  10087:     fputs(line,ficparo);
                   10088:     fputs(line,ficlog);
                   10089:   }
                   10090:   ungetc(c,ficpar);
                   10091: 
                   10092:    
1.145     brouard  10093:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.225     brouard  10094:   coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
1.233     brouard  10095:   cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.225     brouard  10096:   cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
1.136     brouard  10097:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   10098:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   10099:      v1+v2*age+v2*v3 makes cptcovn = 3
                   10100:   */
                   10101:   if (strlen(model)>1) 
1.187     brouard  10102:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  10103:   else
1.187     brouard  10104:     ncovmodel=2; /* Constant and age */
1.133     brouard  10105:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   10106:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  10107:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   10108:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10109:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10110:     fflush(stdout);
                   10111:     fclose (ficlog);
                   10112:     goto end;
                   10113:   }
1.126     brouard  10114:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10115:   delti=delti3[1][1];
                   10116:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   10117:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  10118: /* We could also provide initial parameters values giving by simple logistic regression 
                   10119:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   10120:       /* for(i=1;i<nlstate;i++){ */
                   10121:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10122:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10123:       /* } */
1.126     brouard  10124:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  10125:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   10126:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10127:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   10128:     fclose (ficparo);
                   10129:     fclose (ficlog);
                   10130:     goto end;
                   10131:     exit(0);
1.220     brouard  10132:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  10133:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  10134:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   10135:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10136:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10137:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10138:     hess=matrix(1,npar,1,npar);
1.220     brouard  10139:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  10140:     /* Read guessed parameters */
1.126     brouard  10141:     /* Reads comments: lines beginning with '#' */
                   10142:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10143:       ungetc(c,ficpar);
                   10144:       fgets(line, MAXLINE, ficpar);
                   10145:       numlinepar++;
1.141     brouard  10146:       fputs(line,stdout);
1.126     brouard  10147:       fputs(line,ficparo);
                   10148:       fputs(line,ficlog);
                   10149:     }
                   10150:     ungetc(c,ficpar);
                   10151:     
                   10152:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  10153:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  10154:     for(i=1; i <=nlstate; i++){
1.234     brouard  10155:       j=0;
1.126     brouard  10156:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  10157:        if(jj==i) continue;
                   10158:        j++;
                   10159:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10160:        if ((i1 != i) || (j1 != jj)){
                   10161:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  10162: It might be a problem of design; if ncovcol and the model are correct\n \
                   10163: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  10164:          exit(1);
                   10165:        }
                   10166:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10167:        if(mle==1)
                   10168:          printf("%1d%1d",i,jj);
                   10169:        fprintf(ficlog,"%1d%1d",i,jj);
                   10170:        for(k=1; k<=ncovmodel;k++){
                   10171:          fscanf(ficpar," %lf",&param[i][j][k]);
                   10172:          if(mle==1){
                   10173:            printf(" %lf",param[i][j][k]);
                   10174:            fprintf(ficlog," %lf",param[i][j][k]);
                   10175:          }
                   10176:          else
                   10177:            fprintf(ficlog," %lf",param[i][j][k]);
                   10178:          fprintf(ficparo," %lf",param[i][j][k]);
                   10179:        }
                   10180:        fscanf(ficpar,"\n");
                   10181:        numlinepar++;
                   10182:        if(mle==1)
                   10183:          printf("\n");
                   10184:        fprintf(ficlog,"\n");
                   10185:        fprintf(ficparo,"\n");
1.126     brouard  10186:       }
                   10187:     }  
                   10188:     fflush(ficlog);
1.234     brouard  10189:     
1.251     brouard  10190:     /* Reads parameters values */
1.126     brouard  10191:     p=param[1][1];
1.251     brouard  10192:     pstart=paramstart[1][1];
1.126     brouard  10193:     
                   10194:     /* Reads comments: lines beginning with '#' */
                   10195:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10196:       ungetc(c,ficpar);
                   10197:       fgets(line, MAXLINE, ficpar);
                   10198:       numlinepar++;
1.141     brouard  10199:       fputs(line,stdout);
1.126     brouard  10200:       fputs(line,ficparo);
                   10201:       fputs(line,ficlog);
                   10202:     }
                   10203:     ungetc(c,ficpar);
                   10204: 
                   10205:     for(i=1; i <=nlstate; i++){
                   10206:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  10207:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10208:        if ( (i1-i) * (j1-j) != 0){
                   10209:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   10210:          exit(1);
                   10211:        }
                   10212:        printf("%1d%1d",i,j);
                   10213:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10214:        fprintf(ficlog,"%1d%1d",i1,j1);
                   10215:        for(k=1; k<=ncovmodel;k++){
                   10216:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   10217:          printf(" %le",delti3[i][j][k]);
                   10218:          fprintf(ficparo," %le",delti3[i][j][k]);
                   10219:          fprintf(ficlog," %le",delti3[i][j][k]);
                   10220:        }
                   10221:        fscanf(ficpar,"\n");
                   10222:        numlinepar++;
                   10223:        printf("\n");
                   10224:        fprintf(ficparo,"\n");
                   10225:        fprintf(ficlog,"\n");
1.126     brouard  10226:       }
                   10227:     }
                   10228:     fflush(ficlog);
1.234     brouard  10229:     
1.145     brouard  10230:     /* Reads covariance matrix */
1.126     brouard  10231:     delti=delti3[1][1];
1.220     brouard  10232:                
                   10233:                
1.126     brouard  10234:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  10235:                
1.126     brouard  10236:     /* Reads comments: lines beginning with '#' */
                   10237:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10238:       ungetc(c,ficpar);
                   10239:       fgets(line, MAXLINE, ficpar);
                   10240:       numlinepar++;
1.141     brouard  10241:       fputs(line,stdout);
1.126     brouard  10242:       fputs(line,ficparo);
                   10243:       fputs(line,ficlog);
                   10244:     }
                   10245:     ungetc(c,ficpar);
1.220     brouard  10246:                
1.126     brouard  10247:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10248:     hess=matrix(1,npar,1,npar);
1.131     brouard  10249:     for(i=1; i <=npar; i++)
                   10250:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  10251:                
1.194     brouard  10252:     /* Scans npar lines */
1.126     brouard  10253:     for(i=1; i <=npar; i++){
1.226     brouard  10254:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  10255:       if(count != 3){
1.226     brouard  10256:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10257: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10258: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10259:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10260: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10261: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10262:        exit(1);
1.220     brouard  10263:       }else{
1.226     brouard  10264:        if(mle==1)
                   10265:          printf("%1d%1d%d",i1,j1,jk);
                   10266:       }
                   10267:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   10268:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  10269:       for(j=1; j <=i; j++){
1.226     brouard  10270:        fscanf(ficpar," %le",&matcov[i][j]);
                   10271:        if(mle==1){
                   10272:          printf(" %.5le",matcov[i][j]);
                   10273:        }
                   10274:        fprintf(ficlog," %.5le",matcov[i][j]);
                   10275:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  10276:       }
                   10277:       fscanf(ficpar,"\n");
                   10278:       numlinepar++;
                   10279:       if(mle==1)
1.220     brouard  10280:                                printf("\n");
1.126     brouard  10281:       fprintf(ficlog,"\n");
                   10282:       fprintf(ficparo,"\n");
                   10283:     }
1.194     brouard  10284:     /* End of read covariance matrix npar lines */
1.126     brouard  10285:     for(i=1; i <=npar; i++)
                   10286:       for(j=i+1;j<=npar;j++)
1.226     brouard  10287:        matcov[i][j]=matcov[j][i];
1.126     brouard  10288:     
                   10289:     if(mle==1)
                   10290:       printf("\n");
                   10291:     fprintf(ficlog,"\n");
                   10292:     
                   10293:     fflush(ficlog);
                   10294:     
                   10295:     /*-------- Rewriting parameter file ----------*/
                   10296:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   10297:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   10298:     strcat(rfileres,".");    /* */
                   10299:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10300:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  10301:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10302:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  10303:     }
                   10304:     fprintf(ficres,"#%s\n",version);
                   10305:   }    /* End of mle != -3 */
1.218     brouard  10306:   
1.186     brouard  10307:   /*  Main data
                   10308:    */
1.126     brouard  10309:   n= lastobs;
                   10310:   num=lvector(1,n);
                   10311:   moisnais=vector(1,n);
                   10312:   annais=vector(1,n);
                   10313:   moisdc=vector(1,n);
                   10314:   andc=vector(1,n);
1.220     brouard  10315:   weight=vector(1,n);
1.126     brouard  10316:   agedc=vector(1,n);
                   10317:   cod=ivector(1,n);
1.220     brouard  10318:   for(i=1;i<=n;i++){
1.234     brouard  10319:     num[i]=0;
                   10320:     moisnais[i]=0;
                   10321:     annais[i]=0;
                   10322:     moisdc[i]=0;
                   10323:     andc[i]=0;
                   10324:     agedc[i]=0;
                   10325:     cod[i]=0;
                   10326:     weight[i]=1.0; /* Equal weights, 1 by default */
                   10327:   }
1.126     brouard  10328:   mint=matrix(1,maxwav,1,n);
                   10329:   anint=matrix(1,maxwav,1,n);
1.131     brouard  10330:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  10331:   tab=ivector(1,NCOVMAX);
1.144     brouard  10332:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  10333:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  10334: 
1.136     brouard  10335:   /* Reads data from file datafile */
                   10336:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   10337:     goto end;
                   10338: 
                   10339:   /* Calculation of the number of parameters from char model */
1.234     brouard  10340:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  10341:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   10342:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   10343:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   10344:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  10345:   */
                   10346:   
                   10347:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   10348:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   10349:   TvarsD=ivector(1,NCOVMAX); /*  */
                   10350:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   10351:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  10352:   TvarF=ivector(1,NCOVMAX); /*  */
                   10353:   TvarFind=ivector(1,NCOVMAX); /*  */
                   10354:   TvarV=ivector(1,NCOVMAX); /*  */
                   10355:   TvarVind=ivector(1,NCOVMAX); /*  */
                   10356:   TvarA=ivector(1,NCOVMAX); /*  */
                   10357:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  10358:   TvarFD=ivector(1,NCOVMAX); /*  */
                   10359:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   10360:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   10361:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   10362:   TvarVD=ivector(1,NCOVMAX); /*  */
                   10363:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   10364:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   10365:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   10366: 
1.230     brouard  10367:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  10368:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  10369:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   10370:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   10371:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  10372:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   10373:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   10374:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   10375:   */
                   10376:   /* For model-covariate k tells which data-covariate to use but
                   10377:     because this model-covariate is a construction we invent a new column
                   10378:     ncovcol + k1
                   10379:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   10380:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  10381:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   10382:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  10383:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   10384:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  10385:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  10386:   */
1.145     brouard  10387:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   10388:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  10389:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   10390:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  10391:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  10392:                         4 covariates (3 plus signs)
                   10393:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   10394:                      */  
1.230     brouard  10395:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  10396:                                * individual dummy, fixed or varying:
                   10397:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   10398:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  10399:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   10400:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   10401:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   10402:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   10403:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  10404:                                * individual quantitative, fixed or varying:
                   10405:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   10406:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   10407:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  10408: /* Main decodemodel */
                   10409: 
1.187     brouard  10410: 
1.223     brouard  10411:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  10412:     goto end;
                   10413: 
1.137     brouard  10414:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   10415:     nbwarn++;
                   10416:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10417:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10418:   }
1.136     brouard  10419:     /*  if(mle==1){*/
1.137     brouard  10420:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   10421:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  10422:   }
                   10423: 
                   10424:     /*-calculation of age at interview from date of interview and age at death -*/
                   10425:   agev=matrix(1,maxwav,1,imx);
                   10426: 
                   10427:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   10428:     goto end;
                   10429: 
1.126     brouard  10430: 
1.136     brouard  10431:   agegomp=(int)agemin;
                   10432:   free_vector(moisnais,1,n);
                   10433:   free_vector(annais,1,n);
1.126     brouard  10434:   /* free_matrix(mint,1,maxwav,1,n);
                   10435:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  10436:   /* free_vector(moisdc,1,n); */
                   10437:   /* free_vector(andc,1,n); */
1.145     brouard  10438:   /* */
                   10439:   
1.126     brouard  10440:   wav=ivector(1,imx);
1.214     brouard  10441:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10442:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10443:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10444:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   10445:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   10446:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  10447:    
                   10448:   /* Concatenates waves */
1.214     brouard  10449:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   10450:      Death is a valid wave (if date is known).
                   10451:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   10452:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   10453:      and mw[mi+1][i]. dh depends on stepm.
                   10454:   */
                   10455: 
1.126     brouard  10456:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  10457:   /* Concatenates waves */
1.145     brouard  10458:  
1.215     brouard  10459:   free_vector(moisdc,1,n);
                   10460:   free_vector(andc,1,n);
                   10461: 
1.126     brouard  10462:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   10463:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   10464:   ncodemax[1]=1;
1.145     brouard  10465:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  10466:   cptcoveff=0;
1.220     brouard  10467:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   10468:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  10469:   }
                   10470:   
                   10471:   ncovcombmax=pow(2,cptcoveff);
                   10472:   invalidvarcomb=ivector(1, ncovcombmax); 
                   10473:   for(i=1;i<ncovcombmax;i++)
                   10474:     invalidvarcomb[i]=0;
                   10475:   
1.211     brouard  10476:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  10477:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  10478:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  10479:   
1.200     brouard  10480:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  10481:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  10482:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  10483:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   10484:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   10485:    * (currently 0 or 1) in the data.
                   10486:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   10487:    * corresponding modality (h,j).
                   10488:    */
                   10489: 
1.145     brouard  10490:   h=0;
                   10491:   /*if (cptcovn > 0) */
1.126     brouard  10492:   m=pow(2,cptcoveff);
                   10493:  
1.144     brouard  10494:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  10495:           * For k=4 covariates, h goes from 1 to m=2**k
                   10496:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   10497:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  10498:           *     h\k   1     2     3     4
1.143     brouard  10499:           *______________________________  
                   10500:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   10501:           *     2     2     1     1     1
                   10502:           *     3 i=2 1     2     1     1
                   10503:           *     4     2     2     1     1
                   10504:           *     5 i=3 1 i=2 1     2     1
                   10505:           *     6     2     1     2     1
                   10506:           *     7 i=4 1     2     2     1
                   10507:           *     8     2     2     2     1
1.197     brouard  10508:           *     9 i=5 1 i=3 1 i=2 1     2
                   10509:           *    10     2     1     1     2
                   10510:           *    11 i=6 1     2     1     2
                   10511:           *    12     2     2     1     2
                   10512:           *    13 i=7 1 i=4 1     2     2    
                   10513:           *    14     2     1     2     2
                   10514:           *    15 i=8 1     2     2     2
                   10515:           *    16     2     2     2     2
1.143     brouard  10516:           */
1.212     brouard  10517:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  10518:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   10519:      * and the value of each covariate?
                   10520:      * V1=1, V2=1, V3=2, V4=1 ?
                   10521:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   10522:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   10523:      * In order to get the real value in the data, we use nbcode
                   10524:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   10525:      * We are keeping this crazy system in order to be able (in the future?) 
                   10526:      * to have more than 2 values (0 or 1) for a covariate.
                   10527:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   10528:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   10529:      *              bbbbbbbb
                   10530:      *              76543210     
                   10531:      *   h-1        00000101 (6-1=5)
1.219     brouard  10532:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  10533:      *           &
                   10534:      *     1        00000001 (1)
1.219     brouard  10535:      *              00000000        = 1 & ((h-1) >> (k-1))
                   10536:      *          +1= 00000001 =1 
1.211     brouard  10537:      *
                   10538:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   10539:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   10540:      *    >>k'            11
                   10541:      *          &   00000001
                   10542:      *            = 00000001
                   10543:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   10544:      * Reverse h=6 and m=16?
                   10545:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   10546:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   10547:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   10548:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   10549:      * V3=decodtabm(14,3,2**4)=2
                   10550:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   10551:      *(h-1) >> (j-1)    0011 =13 >> 2
                   10552:      *          &1 000000001
                   10553:      *           = 000000001
                   10554:      *         +1= 000000010 =2
                   10555:      *                  2211
                   10556:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   10557:      *                  V3=2
1.220     brouard  10558:                 * codtabm and decodtabm are identical
1.211     brouard  10559:      */
                   10560: 
1.145     brouard  10561: 
                   10562:  free_ivector(Ndum,-1,NCOVMAX);
                   10563: 
                   10564: 
1.126     brouard  10565:     
1.186     brouard  10566:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  10567:   strcpy(optionfilegnuplot,optionfilefiname);
                   10568:   if(mle==-3)
1.201     brouard  10569:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  10570:   strcat(optionfilegnuplot,".gp");
                   10571: 
                   10572:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   10573:     printf("Problem with file %s",optionfilegnuplot);
                   10574:   }
                   10575:   else{
1.204     brouard  10576:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  10577:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  10578:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   10579:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  10580:   }
                   10581:   /*  fclose(ficgp);*/
1.186     brouard  10582: 
                   10583: 
                   10584:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  10585: 
                   10586:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   10587:   if(mle==-3)
1.201     brouard  10588:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  10589:   strcat(optionfilehtm,".htm");
                   10590:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  10591:     printf("Problem with %s \n",optionfilehtm);
                   10592:     exit(0);
1.126     brouard  10593:   }
                   10594: 
                   10595:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   10596:   strcat(optionfilehtmcov,"-cov.htm");
                   10597:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   10598:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   10599:   }
                   10600:   else{
                   10601:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   10602: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10603: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  10604:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   10605:   }
                   10606: 
1.213     brouard  10607:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  10608: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   10609: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  10610: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10611: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  10612: \n\
                   10613: <hr  size=\"2\" color=\"#EC5E5E\">\
                   10614:  <ul><li><h4>Parameter files</h4>\n\
                   10615:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   10616:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   10617:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   10618:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   10619:  - Date and time at start: %s</ul>\n",\
                   10620:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   10621:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   10622:          fileres,fileres,\
                   10623:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   10624:   fflush(fichtm);
                   10625: 
                   10626:   strcpy(pathr,path);
                   10627:   strcat(pathr,optionfilefiname);
1.184     brouard  10628: #ifdef WIN32
                   10629:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   10630: #else
1.126     brouard  10631:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  10632: #endif
                   10633:          
1.126     brouard  10634:   
1.220     brouard  10635:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   10636:                 and for any valid combination of covariates
1.126     brouard  10637:      and prints on file fileres'p'. */
1.251     brouard  10638:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  10639:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  10640: 
                   10641:   fprintf(fichtm,"\n");
                   10642:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   10643: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   10644: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   10645:          imx,agemin,agemax,jmin,jmax,jmean);
                   10646:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.220     brouard  10647:        oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10648:        newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10649:        savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10650:        oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  10651: 
1.126     brouard  10652:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   10653:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   10654:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   10655: 
                   10656:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  10657:   /* For mortality only */
1.126     brouard  10658:   if (mle==-3){
1.136     brouard  10659:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  10660:     for(i=1;i<=NDIM;i++)
                   10661:       for(j=1;j<=NDIM;j++)
                   10662:        ximort[i][j]=0.;
1.186     brouard  10663:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  10664:     cens=ivector(1,n);
                   10665:     ageexmed=vector(1,n);
                   10666:     agecens=vector(1,n);
                   10667:     dcwave=ivector(1,n);
1.223     brouard  10668:                
1.126     brouard  10669:     for (i=1; i<=imx; i++){
                   10670:       dcwave[i]=-1;
                   10671:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  10672:        if (s[m][i]>nlstate) {
                   10673:          dcwave[i]=m;
                   10674:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   10675:          break;
                   10676:        }
1.126     brouard  10677:     }
1.226     brouard  10678:     
1.126     brouard  10679:     for (i=1; i<=imx; i++) {
                   10680:       if (wav[i]>0){
1.226     brouard  10681:        ageexmed[i]=agev[mw[1][i]][i];
                   10682:        j=wav[i];
                   10683:        agecens[i]=1.; 
                   10684:        
                   10685:        if (ageexmed[i]> 1 && wav[i] > 0){
                   10686:          agecens[i]=agev[mw[j][i]][i];
                   10687:          cens[i]= 1;
                   10688:        }else if (ageexmed[i]< 1) 
                   10689:          cens[i]= -1;
                   10690:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   10691:          cens[i]=0 ;
1.126     brouard  10692:       }
                   10693:       else cens[i]=-1;
                   10694:     }
                   10695:     
                   10696:     for (i=1;i<=NDIM;i++) {
                   10697:       for (j=1;j<=NDIM;j++)
1.226     brouard  10698:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  10699:     }
                   10700:     
1.145     brouard  10701:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  10702:     /*printf("%lf %lf", p[1], p[2]);*/
                   10703:     
                   10704:     
1.136     brouard  10705: #ifdef GSL
                   10706:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  10707: #else
1.126     brouard  10708:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  10709: #endif
1.201     brouard  10710:     strcpy(filerespow,"POW-MORT_"); 
                   10711:     strcat(filerespow,fileresu);
1.126     brouard  10712:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   10713:       printf("Problem with resultfile: %s\n", filerespow);
                   10714:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   10715:     }
1.136     brouard  10716: #ifdef GSL
                   10717:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  10718: #else
1.126     brouard  10719:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  10720: #endif
1.126     brouard  10721:     /*  for (i=1;i<=nlstate;i++)
                   10722:        for(j=1;j<=nlstate+ndeath;j++)
                   10723:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   10724:     */
                   10725:     fprintf(ficrespow,"\n");
1.136     brouard  10726: #ifdef GSL
                   10727:     /* gsl starts here */ 
                   10728:     T = gsl_multimin_fminimizer_nmsimplex;
                   10729:     gsl_multimin_fminimizer *sfm = NULL;
                   10730:     gsl_vector *ss, *x;
                   10731:     gsl_multimin_function minex_func;
                   10732: 
                   10733:     /* Initial vertex size vector */
                   10734:     ss = gsl_vector_alloc (NDIM);
                   10735:     
                   10736:     if (ss == NULL){
                   10737:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   10738:     }
                   10739:     /* Set all step sizes to 1 */
                   10740:     gsl_vector_set_all (ss, 0.001);
                   10741: 
                   10742:     /* Starting point */
1.126     brouard  10743:     
1.136     brouard  10744:     x = gsl_vector_alloc (NDIM);
                   10745:     
                   10746:     if (x == NULL){
                   10747:       gsl_vector_free(ss);
                   10748:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   10749:     }
                   10750:   
                   10751:     /* Initialize method and iterate */
                   10752:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  10753:     /*     gsl_vector_set(x, 0, 0.0268); */
                   10754:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  10755:     gsl_vector_set(x, 0, p[1]);
                   10756:     gsl_vector_set(x, 1, p[2]);
                   10757: 
                   10758:     minex_func.f = &gompertz_f;
                   10759:     minex_func.n = NDIM;
                   10760:     minex_func.params = (void *)&p; /* ??? */
                   10761:     
                   10762:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   10763:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   10764:     
                   10765:     printf("Iterations beginning .....\n\n");
                   10766:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   10767: 
                   10768:     iteri=0;
                   10769:     while (rval == GSL_CONTINUE){
                   10770:       iteri++;
                   10771:       status = gsl_multimin_fminimizer_iterate(sfm);
                   10772:       
                   10773:       if (status) printf("error: %s\n", gsl_strerror (status));
                   10774:       fflush(0);
                   10775:       
                   10776:       if (status) 
                   10777:         break;
                   10778:       
                   10779:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   10780:       ssval = gsl_multimin_fminimizer_size (sfm);
                   10781:       
                   10782:       if (rval == GSL_SUCCESS)
                   10783:         printf ("converged to a local maximum at\n");
                   10784:       
                   10785:       printf("%5d ", iteri);
                   10786:       for (it = 0; it < NDIM; it++){
                   10787:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   10788:       }
                   10789:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   10790:     }
                   10791:     
                   10792:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   10793:     
                   10794:     gsl_vector_free(x); /* initial values */
                   10795:     gsl_vector_free(ss); /* inital step size */
                   10796:     for (it=0; it<NDIM; it++){
                   10797:       p[it+1]=gsl_vector_get(sfm->x,it);
                   10798:       fprintf(ficrespow," %.12lf", p[it]);
                   10799:     }
                   10800:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   10801: #endif
                   10802: #ifdef POWELL
                   10803:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   10804: #endif  
1.126     brouard  10805:     fclose(ficrespow);
                   10806:     
1.203     brouard  10807:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  10808: 
                   10809:     for(i=1; i <=NDIM; i++)
                   10810:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  10811:                                matcov[i][j]=matcov[j][i];
1.126     brouard  10812:     
                   10813:     printf("\nCovariance matrix\n ");
1.203     brouard  10814:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  10815:     for(i=1; i <=NDIM; i++) {
                   10816:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  10817:                                printf("%f ",matcov[i][j]);
                   10818:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  10819:       }
1.203     brouard  10820:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  10821:     }
                   10822:     
                   10823:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  10824:     for (i=1;i<=NDIM;i++) {
1.126     brouard  10825:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  10826:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   10827:     }
1.126     brouard  10828:     lsurv=vector(1,AGESUP);
                   10829:     lpop=vector(1,AGESUP);
                   10830:     tpop=vector(1,AGESUP);
                   10831:     lsurv[agegomp]=100000;
                   10832:     
                   10833:     for (k=agegomp;k<=AGESUP;k++) {
                   10834:       agemortsup=k;
                   10835:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   10836:     }
                   10837:     
                   10838:     for (k=agegomp;k<agemortsup;k++)
                   10839:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   10840:     
                   10841:     for (k=agegomp;k<agemortsup;k++){
                   10842:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   10843:       sumlpop=sumlpop+lpop[k];
                   10844:     }
                   10845:     
                   10846:     tpop[agegomp]=sumlpop;
                   10847:     for (k=agegomp;k<(agemortsup-3);k++){
                   10848:       /*  tpop[k+1]=2;*/
                   10849:       tpop[k+1]=tpop[k]-lpop[k];
                   10850:     }
                   10851:     
                   10852:     
                   10853:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   10854:     for (k=agegomp;k<(agemortsup-2);k++) 
                   10855:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   10856:     
                   10857:     
                   10858:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  10859:                ageminpar=50;
                   10860:                agemaxpar=100;
1.194     brouard  10861:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   10862:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10863: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10864: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   10865:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10866: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10867: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10868:     }else{
                   10869:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   10870:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  10871:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  10872:                }
1.201     brouard  10873:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  10874:                     stepm, weightopt,\
                   10875:                     model,imx,p,matcov,agemortsup);
                   10876:     
                   10877:     free_vector(lsurv,1,AGESUP);
                   10878:     free_vector(lpop,1,AGESUP);
                   10879:     free_vector(tpop,1,AGESUP);
1.220     brouard  10880:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  10881:     free_ivector(cens,1,n);
                   10882:     free_vector(agecens,1,n);
                   10883:     free_ivector(dcwave,1,n);
1.220     brouard  10884: #ifdef GSL
1.136     brouard  10885: #endif
1.186     brouard  10886:   } /* Endof if mle==-3 mortality only */
1.205     brouard  10887:   /* Standard  */
                   10888:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   10889:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10890:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  10891:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  10892:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10893:     for (k=1; k<=npar;k++)
                   10894:       printf(" %d %8.5f",k,p[k]);
                   10895:     printf("\n");
1.205     brouard  10896:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   10897:       /* mlikeli uses func not funcone */
1.247     brouard  10898:       /* for(i=1;i<nlstate;i++){ */
                   10899:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10900:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10901:       /* } */
1.205     brouard  10902:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   10903:     }
                   10904:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   10905:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10906:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   10907:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10908:     }
                   10909:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  10910:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10911:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10912:     for (k=1; k<=npar;k++)
                   10913:       printf(" %d %8.5f",k,p[k]);
                   10914:     printf("\n");
                   10915:     
                   10916:     /*--------- results files --------------*/
1.224     brouard  10917:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  10918:     
                   10919:     
                   10920:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10921:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10922:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10923:     for(i=1,jk=1; i <=nlstate; i++){
                   10924:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  10925:        if (k != i) {
                   10926:          printf("%d%d ",i,k);
                   10927:          fprintf(ficlog,"%d%d ",i,k);
                   10928:          fprintf(ficres,"%1d%1d ",i,k);
                   10929:          for(j=1; j <=ncovmodel; j++){
                   10930:            printf("%12.7f ",p[jk]);
                   10931:            fprintf(ficlog,"%12.7f ",p[jk]);
                   10932:            fprintf(ficres,"%12.7f ",p[jk]);
                   10933:            jk++; 
                   10934:          }
                   10935:          printf("\n");
                   10936:          fprintf(ficlog,"\n");
                   10937:          fprintf(ficres,"\n");
                   10938:        }
1.126     brouard  10939:       }
                   10940:     }
1.203     brouard  10941:     if(mle != 0){
                   10942:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  10943:       ftolhess=ftol; /* Usually correct */
1.203     brouard  10944:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   10945:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10946:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10947:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  10948:        for(k=1; k <=(nlstate+ndeath); k++){
                   10949:          if (k != i) {
                   10950:            printf("%d%d ",i,k);
                   10951:            fprintf(ficlog,"%d%d ",i,k);
                   10952:            for(j=1; j <=ncovmodel; j++){
                   10953:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10954:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10955:              jk++; 
                   10956:            }
                   10957:            printf("\n");
                   10958:            fprintf(ficlog,"\n");
                   10959:          }
                   10960:        }
1.193     brouard  10961:       }
1.203     brouard  10962:     } /* end of hesscov and Wald tests */
1.225     brouard  10963:     
1.203     brouard  10964:     /*  */
1.126     brouard  10965:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   10966:     printf("# Scales (for hessian or gradient estimation)\n");
                   10967:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   10968:     for(i=1,jk=1; i <=nlstate; i++){
                   10969:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  10970:        if (j!=i) {
                   10971:          fprintf(ficres,"%1d%1d",i,j);
                   10972:          printf("%1d%1d",i,j);
                   10973:          fprintf(ficlog,"%1d%1d",i,j);
                   10974:          for(k=1; k<=ncovmodel;k++){
                   10975:            printf(" %.5e",delti[jk]);
                   10976:            fprintf(ficlog," %.5e",delti[jk]);
                   10977:            fprintf(ficres," %.5e",delti[jk]);
                   10978:            jk++;
                   10979:          }
                   10980:          printf("\n");
                   10981:          fprintf(ficlog,"\n");
                   10982:          fprintf(ficres,"\n");
                   10983:        }
1.126     brouard  10984:       }
                   10985:     }
                   10986:     
                   10987:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  10988:     if(mle >= 1) /* To big for the screen */
1.126     brouard  10989:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   10990:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   10991:     /* # 121 Var(a12)\n\ */
                   10992:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   10993:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   10994:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   10995:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   10996:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   10997:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   10998:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   10999:     
                   11000:     
                   11001:     /* Just to have a covariance matrix which will be more understandable
                   11002:        even is we still don't want to manage dictionary of variables
                   11003:     */
                   11004:     for(itimes=1;itimes<=2;itimes++){
                   11005:       jj=0;
                   11006:       for(i=1; i <=nlstate; i++){
1.225     brouard  11007:        for(j=1; j <=nlstate+ndeath; j++){
                   11008:          if(j==i) continue;
                   11009:          for(k=1; k<=ncovmodel;k++){
                   11010:            jj++;
                   11011:            ca[0]= k+'a'-1;ca[1]='\0';
                   11012:            if(itimes==1){
                   11013:              if(mle>=1)
                   11014:                printf("#%1d%1d%d",i,j,k);
                   11015:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   11016:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   11017:            }else{
                   11018:              if(mle>=1)
                   11019:                printf("%1d%1d%d",i,j,k);
                   11020:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   11021:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   11022:            }
                   11023:            ll=0;
                   11024:            for(li=1;li <=nlstate; li++){
                   11025:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   11026:                if(lj==li) continue;
                   11027:                for(lk=1;lk<=ncovmodel;lk++){
                   11028:                  ll++;
                   11029:                  if(ll<=jj){
                   11030:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   11031:                    if(ll<jj){
                   11032:                      if(itimes==1){
                   11033:                        if(mle>=1)
                   11034:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11035:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11036:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11037:                      }else{
                   11038:                        if(mle>=1)
                   11039:                          printf(" %.5e",matcov[jj][ll]); 
                   11040:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   11041:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   11042:                      }
                   11043:                    }else{
                   11044:                      if(itimes==1){
                   11045:                        if(mle>=1)
                   11046:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   11047:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   11048:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   11049:                      }else{
                   11050:                        if(mle>=1)
                   11051:                          printf(" %.7e",matcov[jj][ll]); 
                   11052:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   11053:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   11054:                      }
                   11055:                    }
                   11056:                  }
                   11057:                } /* end lk */
                   11058:              } /* end lj */
                   11059:            } /* end li */
                   11060:            if(mle>=1)
                   11061:              printf("\n");
                   11062:            fprintf(ficlog,"\n");
                   11063:            fprintf(ficres,"\n");
                   11064:            numlinepar++;
                   11065:          } /* end k*/
                   11066:        } /*end j */
1.126     brouard  11067:       } /* end i */
                   11068:     } /* end itimes */
                   11069:     
                   11070:     fflush(ficlog);
                   11071:     fflush(ficres);
1.225     brouard  11072:     while(fgets(line, MAXLINE, ficpar)) {
                   11073:       /* If line starts with a # it is a comment */
                   11074:       if (line[0] == '#') {
                   11075:        numlinepar++;
                   11076:        fputs(line,stdout);
                   11077:        fputs(line,ficparo);
                   11078:        fputs(line,ficlog);
                   11079:        continue;
                   11080:       }else
                   11081:        break;
                   11082:     }
                   11083:     
1.209     brouard  11084:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11085:     /*   ungetc(c,ficpar); */
                   11086:     /*   fgets(line, MAXLINE, ficpar); */
                   11087:     /*   fputs(line,stdout); */
                   11088:     /*   fputs(line,ficparo); */
                   11089:     /* } */
                   11090:     /* ungetc(c,ficpar); */
1.126     brouard  11091:     
                   11092:     estepm=0;
1.209     brouard  11093:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  11094:       
                   11095:       if (num_filled != 6) {
                   11096:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11097:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11098:        goto end;
                   11099:       }
                   11100:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   11101:     }
                   11102:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   11103:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   11104:     
1.209     brouard  11105:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  11106:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   11107:     if (fage <= 2) {
                   11108:       bage = ageminpar;
                   11109:       fage = agemaxpar;
                   11110:     }
                   11111:     
                   11112:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  11113:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   11114:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  11115:                
1.186     brouard  11116:     /* Other stuffs, more or less useful */    
1.254   ! brouard  11117:     while(fgets(line, MAXLINE, ficpar)) {
        !          11118:       /* If line starts with a # it is a comment */
        !          11119:       if (line[0] == '#') {
        !          11120:        numlinepar++;
        !          11121:        fputs(line,stdout);
        !          11122:        fputs(line,ficparo);
        !          11123:        fputs(line,ficlog);
        !          11124:        continue;
        !          11125:       }else
        !          11126:        break;
        !          11127:     }
        !          11128: 
        !          11129:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
        !          11130:       
        !          11131:       if (num_filled != 7) {
        !          11132:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
        !          11133:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
        !          11134:        goto end;
        !          11135:       }
        !          11136:     /* fscanf(ficpar,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav); */
        !          11137:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
        !          11138:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
        !          11139:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
        !          11140:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
        !          11141:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  11142:     }
1.254   ! brouard  11143: 
        !          11144:     while(fgets(line, MAXLINE, ficpar)) {
        !          11145:       /* If line starts with a # it is a comment */
        !          11146:       if (line[0] == '#') {
        !          11147:        numlinepar++;
        !          11148:        fputs(line,stdout);
        !          11149:        fputs(line,ficparo);
        !          11150:        fputs(line,ficlog);
        !          11151:        continue;
        !          11152:       }else
        !          11153:        break;
1.126     brouard  11154:     }
                   11155:     
                   11156:     
                   11157:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   11158:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   11159:     
1.254   ! brouard  11160:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
        !          11161:       if (num_filled != 1) {
        !          11162:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
        !          11163:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
        !          11164:        goto end;
        !          11165:       }
        !          11166:       printf("pop_based=%d\n",popbased);
        !          11167:       fprintf(ficlog,"pop_based=%d\n",popbased);
        !          11168:       fprintf(ficparo,"pop_based=%d\n",popbased);   
        !          11169:       fprintf(ficres,"pop_based=%d\n",popbased);   
        !          11170:     }
        !          11171:      
        !          11172:     while(fgets(line, MAXLINE, ficpar)) {
        !          11173:       /* If line starts with a # it is a comment */
        !          11174:       if (line[0] == '#') {
        !          11175:        numlinepar++;
        !          11176:        fputs(line,stdout);
        !          11177:        fputs(line,ficparo);
        !          11178:        fputs(line,ficlog);
        !          11179:        continue;
        !          11180:       }else
        !          11181:        break;
1.126     brouard  11182:     }
1.254   ! brouard  11183:    /* while((c=getc(ficpar))=='#' && c!= EOF){ */
        !          11184:    /*    ungetc(c,ficpar); */
        !          11185:    /*    fgets(line, MAXLINE, ficpar); */
        !          11186:    /*    fputs(line,stdout); */
        !          11187:    /*    fputs(line,ficres); */
        !          11188:    /*    fputs(line,ficparo); */
        !          11189:    /*  } */
        !          11190:    /*  ungetc(c,ficpar); */
        !          11191:     
        !          11192:     /* fscanf(ficpar,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj); */
        !          11193:     if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
        !          11194:       if (num_filled != 8) {
        !          11195:        printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
        !          11196:        fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
        !          11197:        goto end;
        !          11198:       }
        !          11199:      fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
        !          11200:      printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
        !          11201:      fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
        !          11202:      fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
1.126     brouard  11203:     /* day and month of proj2 are not used but only year anproj2.*/
1.217     brouard  11204:     }
1.254   ! brouard  11205:      while(fgets(line, MAXLINE, ficpar)) {
        !          11206:       /* If line starts with a # it is a comment */
        !          11207:       if (line[0] == '#') {
        !          11208:        numlinepar++;
        !          11209:        fputs(line,stdout);
        !          11210:        fputs(line,ficparo);
        !          11211:        fputs(line,ficlog);
        !          11212:        continue;
        !          11213:       }else
        !          11214:        break;
        !          11215:     }
        !          11216:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
        !          11217:     /*   ungetc(c,ficpar); */
        !          11218:     /*   fgets(line, MAXLINE, ficpar); */
        !          11219:     /*   fputs(line,stdout); */
        !          11220:     /*   fputs(line,ficparo); */
        !          11221:     /*   fputs(line,ficres); */
        !          11222:     /* } */
        !          11223:     /* ungetc(c,ficpar); */
1.217     brouard  11224:     
                   11225:     fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);
1.254   ! brouard  11226:     if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
        !          11227:       if (num_filled != 8) {
        !          11228:        printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 finloal-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
        !          11229:        fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 finloal-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
        !          11230:        goto end;
        !          11231:       }
        !          11232:       printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
        !          11233:       fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
        !          11234:       fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
        !          11235:       fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
1.217     brouard  11236:     /* day and month of proj2 are not used but only year anproj2.*/
1.254   ! brouard  11237:     }
1.230     brouard  11238:     /* Results */
1.235     brouard  11239:     nresult=0;
1.230     brouard  11240:     while(fgets(line, MAXLINE, ficpar)) {
                   11241:       /* If line starts with a # it is a comment */
                   11242:       if (line[0] == '#') {
                   11243:        numlinepar++;
                   11244:        fputs(line,stdout);
                   11245:        fputs(line,ficparo);
                   11246:        fputs(line,ficlog);
1.238     brouard  11247:        fputs(line,ficres);
1.230     brouard  11248:        continue;
                   11249:       }else
                   11250:        break;
                   11251:     }
1.240     brouard  11252:     if (!feof(ficpar))
1.230     brouard  11253:     while((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
1.240     brouard  11254:       if (num_filled == 0){
1.230     brouard  11255:        resultline[0]='\0';
1.253     brouard  11256:        printf("Warning %d: no result line should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
1.240     brouard  11257:       break;
                   11258:       } else if (num_filled != 1){
1.253     brouard  11259:        printf("ERROR %d: result line should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
1.230     brouard  11260:       }
1.235     brouard  11261:       nresult++; /* Sum of resultlines */
                   11262:       printf("Result %d: result=%s\n",nresult, resultline);
                   11263:       if(nresult > MAXRESULTLINES){
                   11264:        printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11265:        fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11266:        goto end;
                   11267:       }
                   11268:       decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
1.238     brouard  11269:       fprintf(ficparo,"result: %s\n",resultline);
                   11270:       fprintf(ficres,"result: %s\n",resultline);
                   11271:       fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  11272:       while(fgets(line, MAXLINE, ficpar)) {
                   11273:        /* If line starts with a # it is a comment */
                   11274:        if (line[0] == '#') {
                   11275:          numlinepar++;
                   11276:          fputs(line,stdout);
                   11277:          fputs(line,ficparo);
1.238     brouard  11278:          fputs(line,ficres);
1.230     brouard  11279:          fputs(line,ficlog);
                   11280:          continue;
                   11281:        }else
                   11282:          break;
                   11283:       }
                   11284:       if (feof(ficpar))
                   11285:        break;
                   11286:       else{ /* Processess output results for this combination of covariate values */
                   11287:       }                                   
1.240     brouard  11288:     } /* end while */
1.230     brouard  11289: 
                   11290: 
1.126     brouard  11291:     
1.230     brouard  11292:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  11293:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  11294:     
                   11295:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  11296:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  11297:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11298: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11299: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  11300:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11301: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11302: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11303:     }else{
1.218     brouard  11304:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p);
1.220     brouard  11305:     }
                   11306:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.225     brouard  11307:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,prevfcast,backcast, estepm, \
                   11308:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  11309:                
1.225     brouard  11310:     /*------------ free_vector  -------------*/
                   11311:     /*  chdir(path); */
1.220     brouard  11312:                
1.215     brouard  11313:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   11314:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   11315:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   11316:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  11317:     free_lvector(num,1,n);
                   11318:     free_vector(agedc,1,n);
                   11319:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   11320:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   11321:     fclose(ficparo);
                   11322:     fclose(ficres);
1.220     brouard  11323:                
                   11324:                
1.186     brouard  11325:     /* Other results (useful)*/
1.220     brouard  11326:                
                   11327:                
1.126     brouard  11328:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  11329:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   11330:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  11331:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  11332:     fclose(ficrespl);
                   11333: 
                   11334:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  11335:     /*#include "hpijx.h"*/
                   11336:     hPijx(p, bage, fage);
1.145     brouard  11337:     fclose(ficrespij);
1.227     brouard  11338:     
1.220     brouard  11339:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  11340:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  11341:     k=1;
1.126     brouard  11342:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  11343:     
1.219     brouard  11344:     /* Prevalence for each covariates in probs[age][status][cov] */
1.218     brouard  11345:     probs= ma3x(1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.126     brouard  11346:     for(i=1;i<=AGESUP;i++)
1.219     brouard  11347:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  11348:        for(k=1;k<=ncovcombmax;k++)
                   11349:          probs[i][j][k]=0.;
1.219     brouard  11350:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
                   11351:     if (mobilav!=0 ||mobilavproj !=0 ) {
                   11352:       mobaverages= ma3x(1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.227     brouard  11353:       for(i=1;i<=AGESUP;i++)
                   11354:        for(j=1;j<=nlstate;j++)
                   11355:          for(k=1;k<=ncovcombmax;k++)
                   11356:            mobaverages[i][j][k]=0.;
1.219     brouard  11357:       mobaverage=mobaverages;
                   11358:       if (mobilav!=0) {
1.235     brouard  11359:        printf("Movingaveraging observed prevalence\n");
1.227     brouard  11360:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   11361:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   11362:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   11363:        }
1.219     brouard  11364:       }
                   11365:       /* /\* Prevalence for each covariates in probs[age][status][cov] *\/ */
                   11366:       /* prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   11367:       else if (mobilavproj !=0) {
1.235     brouard  11368:        printf("Movingaveraging projected observed prevalence\n");
1.227     brouard  11369:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   11370:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11371:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11372:        }
1.219     brouard  11373:       }
                   11374:     }/* end if moving average */
1.227     brouard  11375:     
1.126     brouard  11376:     /*---------- Forecasting ------------------*/
                   11377:     /*if((stepm == 1) && (strcmp(model,".")==0)){*/
                   11378:     if(prevfcast==1){
                   11379:       /*    if(stepm ==1){*/
1.225     brouard  11380:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  11381:     }
1.217     brouard  11382:     if(backcast==1){
1.219     brouard  11383:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11384:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11385:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   11386: 
                   11387:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   11388: 
                   11389:       bprlim=matrix(1,nlstate,1,nlstate);
                   11390:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   11391:       fclose(ficresplb);
                   11392: 
1.222     brouard  11393:       hBijx(p, bage, fage, mobaverage);
                   11394:       fclose(ficrespijb);
1.219     brouard  11395:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11396: 
                   11397:       /* prevbackforecast(fileresu, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, mobilavproj,
1.225     brouard  11398:         bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
1.219     brouard  11399:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11400:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11401:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11402:     }
1.217     brouard  11403:     
1.186     brouard  11404:  
                   11405:     /* ------ Other prevalence ratios------------ */
1.126     brouard  11406: 
1.215     brouard  11407:     free_ivector(wav,1,imx);
                   11408:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   11409:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   11410:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  11411:                
                   11412:                
1.127     brouard  11413:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  11414:                
1.201     brouard  11415:     strcpy(filerese,"E_");
                   11416:     strcat(filerese,fileresu);
1.126     brouard  11417:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   11418:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11419:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11420:     }
1.208     brouard  11421:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   11422:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  11423: 
                   11424:     pstamp(ficreseij);
1.219     brouard  11425:                
1.235     brouard  11426:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11427:     if (cptcovn < 1){i1=1;}
                   11428:     
                   11429:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11430:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11431:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11432:        continue;
1.219     brouard  11433:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  11434:       printf("\n#****** ");
1.225     brouard  11435:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11436:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11437:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11438:       }
                   11439:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11440:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11441:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  11442:       }
                   11443:       fprintf(ficreseij,"******\n");
1.235     brouard  11444:       printf("******\n");
1.219     brouard  11445:       
                   11446:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11447:       oldm=oldms;savm=savms;
1.235     brouard  11448:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  11449:       
1.219     brouard  11450:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  11451:     }
                   11452:     fclose(ficreseij);
1.208     brouard  11453:     printf("done evsij\n");fflush(stdout);
                   11454:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.218     brouard  11455:                
1.227     brouard  11456:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  11457:                
                   11458:                
1.201     brouard  11459:     strcpy(filerest,"T_");
                   11460:     strcat(filerest,fileresu);
1.127     brouard  11461:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   11462:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   11463:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   11464:     }
1.208     brouard  11465:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   11466:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.218     brouard  11467:                
1.126     brouard  11468: 
1.201     brouard  11469:     strcpy(fileresstde,"STDE_");
                   11470:     strcat(fileresstde,fileresu);
1.126     brouard  11471:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  11472:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   11473:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  11474:     }
1.227     brouard  11475:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   11476:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  11477: 
1.201     brouard  11478:     strcpy(filerescve,"CVE_");
                   11479:     strcat(filerescve,fileresu);
1.126     brouard  11480:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  11481:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   11482:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  11483:     }
1.227     brouard  11484:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   11485:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  11486: 
1.201     brouard  11487:     strcpy(fileresv,"V_");
                   11488:     strcat(fileresv,fileresu);
1.126     brouard  11489:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   11490:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11491:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11492:     }
1.227     brouard  11493:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   11494:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  11495: 
1.145     brouard  11496:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11497:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   11498:           
1.235     brouard  11499:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11500:     if (cptcovn < 1){i1=1;}
                   11501:     
                   11502:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11503:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11504:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11505:        continue;
1.242     brouard  11506:       printf("\n#****** Result for:");
                   11507:       fprintf(ficrest,"\n#****** Result for:");
                   11508:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  11509:       for(j=1;j<=cptcoveff;j++){ 
                   11510:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11511:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11512:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11513:       }
1.235     brouard  11514:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11515:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11516:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11517:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11518:       }        
1.208     brouard  11519:       fprintf(ficrest,"******\n");
1.227     brouard  11520:       fprintf(ficlog,"******\n");
                   11521:       printf("******\n");
1.208     brouard  11522:       
                   11523:       fprintf(ficresstdeij,"\n#****** ");
                   11524:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  11525:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11526:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11527:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  11528:       }
1.235     brouard  11529:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11530:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11531:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11532:       }        
1.208     brouard  11533:       fprintf(ficresstdeij,"******\n");
                   11534:       fprintf(ficrescveij,"******\n");
                   11535:       
                   11536:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  11537:       /* pstamp(ficresvij); */
1.225     brouard  11538:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  11539:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11540:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11541:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11542:       }        
1.208     brouard  11543:       fprintf(ficresvij,"******\n");
                   11544:       
                   11545:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11546:       oldm=oldms;savm=savms;
1.235     brouard  11547:       printf(" cvevsij ");
                   11548:       fprintf(ficlog, " cvevsij ");
                   11549:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  11550:       printf(" end cvevsij \n ");
                   11551:       fprintf(ficlog, " end cvevsij \n ");
                   11552:       
                   11553:       /*
                   11554:        */
                   11555:       /* goto endfree; */
                   11556:       
                   11557:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11558:       pstamp(ficrest);
                   11559:       
                   11560:       
                   11561:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  11562:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   11563:        cptcod= 0; /* To be deleted */
                   11564:        printf("varevsij vpopbased=%d \n",vpopbased);
                   11565:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  11566:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  11567:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   11568:        if(vpopbased==1)
                   11569:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   11570:        else
                   11571:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   11572:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   11573:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   11574:        fprintf(ficrest,"\n");
                   11575:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   11576:        epj=vector(1,nlstate+1);
                   11577:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   11578:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   11579:        for(age=bage; age <=fage ;age++){
1.235     brouard  11580:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  11581:          if (vpopbased==1) {
                   11582:            if(mobilav ==0){
                   11583:              for(i=1; i<=nlstate;i++)
                   11584:                prlim[i][i]=probs[(int)age][i][k];
                   11585:            }else{ /* mobilav */ 
                   11586:              for(i=1; i<=nlstate;i++)
                   11587:                prlim[i][i]=mobaverage[(int)age][i][k];
                   11588:            }
                   11589:          }
1.219     brouard  11590:          
1.227     brouard  11591:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   11592:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   11593:          /* printf(" age %4.0f ",age); */
                   11594:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   11595:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   11596:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   11597:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   11598:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   11599:            }
                   11600:            epj[nlstate+1] +=epj[j];
                   11601:          }
                   11602:          /* printf(" age %4.0f \n",age); */
1.219     brouard  11603:          
1.227     brouard  11604:          for(i=1, vepp=0.;i <=nlstate;i++)
                   11605:            for(j=1;j <=nlstate;j++)
                   11606:              vepp += vareij[i][j][(int)age];
                   11607:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   11608:          for(j=1;j <=nlstate;j++){
                   11609:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   11610:          }
                   11611:          fprintf(ficrest,"\n");
                   11612:        }
1.208     brouard  11613:       } /* End vpopbased */
                   11614:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11615:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11616:       free_vector(epj,1,nlstate+1);
1.235     brouard  11617:       printf("done selection\n");fflush(stdout);
                   11618:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  11619:       
1.145     brouard  11620:       /*}*/
1.235     brouard  11621:     } /* End k selection */
1.227     brouard  11622: 
                   11623:     printf("done State-specific expectancies\n");fflush(stdout);
                   11624:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   11625: 
1.126     brouard  11626:     /*------- Variance of period (stable) prevalence------*/   
1.227     brouard  11627:     
1.201     brouard  11628:     strcpy(fileresvpl,"VPL_");
                   11629:     strcat(fileresvpl,fileresu);
1.126     brouard  11630:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   11631:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   11632:       exit(0);
                   11633:     }
1.208     brouard  11634:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   11635:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.227     brouard  11636:     
1.145     brouard  11637:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11638:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
1.227     brouard  11639:     
1.235     brouard  11640:     i1=pow(2,cptcoveff);
                   11641:     if (cptcovn < 1){i1=1;}
                   11642: 
                   11643:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11644:     for(k=1; k<=i1;k++){
1.253     brouard  11645:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11646:        continue;
1.227     brouard  11647:       fprintf(ficresvpl,"\n#****** ");
                   11648:       printf("\n#****** ");
                   11649:       fprintf(ficlog,"\n#****** ");
                   11650:       for(j=1;j<=cptcoveff;j++) {
                   11651:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11652:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11653:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11654:       }
1.235     brouard  11655:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11656:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11657:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11658:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11659:       }        
1.227     brouard  11660:       fprintf(ficresvpl,"******\n");
                   11661:       printf("******\n");
                   11662:       fprintf(ficlog,"******\n");
                   11663:       
                   11664:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   11665:       oldm=oldms;savm=savms;
1.235     brouard  11666:       varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, strstart, nres);
1.227     brouard  11667:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
1.145     brouard  11668:       /*}*/
1.126     brouard  11669:     }
1.227     brouard  11670:     
1.126     brouard  11671:     fclose(ficresvpl);
1.208     brouard  11672:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   11673:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
1.227     brouard  11674:     
                   11675:     free_vector(weight,1,n);
                   11676:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   11677:     free_imatrix(s,1,maxwav+1,1,n);
                   11678:     free_matrix(anint,1,maxwav,1,n); 
                   11679:     free_matrix(mint,1,maxwav,1,n);
                   11680:     free_ivector(cod,1,n);
                   11681:     free_ivector(tab,1,NCOVMAX);
                   11682:     fclose(ficresstdeij);
                   11683:     fclose(ficrescveij);
                   11684:     fclose(ficresvij);
                   11685:     fclose(ficrest);
                   11686:     fclose(ficpar);
                   11687:     
                   11688:     
1.126     brouard  11689:     /*---------- End : free ----------------*/
1.219     brouard  11690:     if (mobilav!=0 ||mobilavproj !=0)
                   11691:       free_ma3x(mobaverages,1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
1.218     brouard  11692:     free_ma3x(probs,1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  11693:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11694:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  11695:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  11696:   /* endfree:*/
                   11697:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11698:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11699:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11700:   free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
1.233     brouard  11701:   free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
1.227     brouard  11702:   free_matrix(coqvar,1,maxwav,1,n);
                   11703:   free_matrix(covar,0,NCOVMAX,1,n);
                   11704:   free_matrix(matcov,1,npar,1,npar);
                   11705:   free_matrix(hess,1,npar,1,npar);
                   11706:   /*free_vector(delti,1,npar);*/
                   11707:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11708:   free_matrix(agev,1,maxwav,1,imx);
                   11709:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   11710:   
                   11711:   free_ivector(ncodemax,1,NCOVMAX);
                   11712:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   11713:   free_ivector(Dummy,-1,NCOVMAX);
                   11714:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  11715:   free_ivector(DummyV,1,NCOVMAX);
                   11716:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  11717:   free_ivector(Typevar,-1,NCOVMAX);
                   11718:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  11719:   free_ivector(TvarsQ,1,NCOVMAX);
                   11720:   free_ivector(TvarsQind,1,NCOVMAX);
                   11721:   free_ivector(TvarsD,1,NCOVMAX);
                   11722:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  11723:   free_ivector(TvarFD,1,NCOVMAX);
                   11724:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  11725:   free_ivector(TvarF,1,NCOVMAX);
                   11726:   free_ivector(TvarFind,1,NCOVMAX);
                   11727:   free_ivector(TvarV,1,NCOVMAX);
                   11728:   free_ivector(TvarVind,1,NCOVMAX);
                   11729:   free_ivector(TvarA,1,NCOVMAX);
                   11730:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  11731:   free_ivector(TvarFQ,1,NCOVMAX);
                   11732:   free_ivector(TvarFQind,1,NCOVMAX);
                   11733:   free_ivector(TvarVD,1,NCOVMAX);
                   11734:   free_ivector(TvarVDind,1,NCOVMAX);
                   11735:   free_ivector(TvarVQ,1,NCOVMAX);
                   11736:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  11737:   free_ivector(Tvarsel,1,NCOVMAX);
                   11738:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  11739:   free_ivector(Tposprod,1,NCOVMAX);
                   11740:   free_ivector(Tprod,1,NCOVMAX);
                   11741:   free_ivector(Tvaraff,1,NCOVMAX);
                   11742:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   11743:   free_ivector(Tage,1,NCOVMAX);
                   11744:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  11745:   free_ivector(TmodelInvind,1,NCOVMAX);
                   11746:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  11747:   
                   11748:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   11749:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  11750:   fflush(fichtm);
                   11751:   fflush(ficgp);
                   11752:   
1.227     brouard  11753:   
1.126     brouard  11754:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  11755:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   11756:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  11757:   }else{
                   11758:     printf("End of Imach\n");
                   11759:     fprintf(ficlog,"End of Imach\n");
                   11760:   }
                   11761:   printf("See log file on %s\n",filelog);
                   11762:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  11763:   /*(void) gettimeofday(&end_time,&tzp);*/
                   11764:   rend_time = time(NULL);  
                   11765:   end_time = *localtime(&rend_time);
                   11766:   /* tml = *localtime(&end_time.tm_sec); */
                   11767:   strcpy(strtend,asctime(&end_time));
1.126     brouard  11768:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   11769:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  11770:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  11771:   
1.157     brouard  11772:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   11773:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   11774:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  11775:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   11776: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   11777:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11778:   fclose(fichtm);
                   11779:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11780:   fclose(fichtmcov);
                   11781:   fclose(ficgp);
                   11782:   fclose(ficlog);
                   11783:   /*------ End -----------*/
1.227     brouard  11784:   
                   11785:   
                   11786:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  11787: #ifdef WIN32
1.227     brouard  11788:   if (_chdir(pathcd) != 0)
                   11789:     printf("Can't move to directory %s!\n",path);
                   11790:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  11791: #else
1.227     brouard  11792:     if(chdir(pathcd) != 0)
                   11793:       printf("Can't move to directory %s!\n", path);
                   11794:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  11795: #endif 
1.126     brouard  11796:     printf("Current directory %s!\n",pathcd);
                   11797:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   11798:   sprintf(plotcmd,"gnuplot");
1.157     brouard  11799: #ifdef _WIN32
1.126     brouard  11800:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   11801: #endif
                   11802:   if(!stat(plotcmd,&info)){
1.158     brouard  11803:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11804:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  11805:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  11806:     }else
                   11807:       strcpy(pplotcmd,plotcmd);
1.157     brouard  11808: #ifdef __unix
1.126     brouard  11809:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   11810:     if(!stat(plotcmd,&info)){
1.158     brouard  11811:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11812:     }else
                   11813:       strcpy(pplotcmd,plotcmd);
                   11814: #endif
                   11815:   }else
                   11816:     strcpy(pplotcmd,plotcmd);
                   11817:   
                   11818:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  11819:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  11820:   
1.126     brouard  11821:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  11822:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  11823:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  11824:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  11825:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  11826:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  11827:   }
1.158     brouard  11828:   printf(" Successful, please wait...");
1.126     brouard  11829:   while (z[0] != 'q') {
                   11830:     /* chdir(path); */
1.154     brouard  11831:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  11832:     scanf("%s",z);
                   11833: /*     if (z[0] == 'c') system("./imach"); */
                   11834:     if (z[0] == 'e') {
1.158     brouard  11835: #ifdef __APPLE__
1.152     brouard  11836:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  11837: #elif __linux
                   11838:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  11839: #else
1.152     brouard  11840:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  11841: #endif
                   11842:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   11843:       system(pplotcmd);
1.126     brouard  11844:     }
                   11845:     else if (z[0] == 'g') system(plotcmd);
                   11846:     else if (z[0] == 'q') exit(0);
                   11847:   }
1.227     brouard  11848: end:
1.126     brouard  11849:   while (z[0] != 'q') {
1.195     brouard  11850:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  11851:     scanf("%s",z);
                   11852:   }
                   11853: }

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