Annotation of imach/src/imach.c, revision 1.255

1.255   ! brouard     1: /* $Id: imach.c,v 1.254 2017/03/08 07:13:00 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.255   ! brouard     4:   Revision 1.254  2017/03/08 07:13:00  brouard
        !             5:   Summary: Fixing data parameter line
        !             6: 
1.254     brouard     7:   Revision 1.253  2016/12/15 11:59:41  brouard
                      8:   Summary: 0.99 in progress
                      9: 
1.253     brouard    10:   Revision 1.252  2016/09/15 21:15:37  brouard
                     11:   *** empty log message ***
                     12: 
1.252     brouard    13:   Revision 1.251  2016/09/15 15:01:13  brouard
                     14:   Summary: not working
                     15: 
1.251     brouard    16:   Revision 1.250  2016/09/08 16:07:27  brouard
                     17:   Summary: continue
                     18: 
1.250     brouard    19:   Revision 1.249  2016/09/07 17:14:18  brouard
                     20:   Summary: Starting values from frequencies
                     21: 
1.249     brouard    22:   Revision 1.248  2016/09/07 14:10:18  brouard
                     23:   *** empty log message ***
                     24: 
1.248     brouard    25:   Revision 1.247  2016/09/02 11:11:21  brouard
                     26:   *** empty log message ***
                     27: 
1.247     brouard    28:   Revision 1.246  2016/09/02 08:49:22  brouard
                     29:   *** empty log message ***
                     30: 
1.246     brouard    31:   Revision 1.245  2016/09/02 07:25:01  brouard
                     32:   *** empty log message ***
                     33: 
1.245     brouard    34:   Revision 1.244  2016/09/02 07:17:34  brouard
                     35:   *** empty log message ***
                     36: 
1.244     brouard    37:   Revision 1.243  2016/09/02 06:45:35  brouard
                     38:   *** empty log message ***
                     39: 
1.243     brouard    40:   Revision 1.242  2016/08/30 15:01:20  brouard
                     41:   Summary: Fixing a lots
                     42: 
1.242     brouard    43:   Revision 1.241  2016/08/29 17:17:25  brouard
                     44:   Summary: gnuplot problem in Back projection to fix
                     45: 
1.241     brouard    46:   Revision 1.240  2016/08/29 07:53:18  brouard
                     47:   Summary: Better
                     48: 
1.240     brouard    49:   Revision 1.239  2016/08/26 15:51:03  brouard
                     50:   Summary: Improvement in Powell output in order to copy and paste
                     51: 
                     52:   Author:
                     53: 
1.239     brouard    54:   Revision 1.238  2016/08/26 14:23:35  brouard
                     55:   Summary: Starting tests of 0.99
                     56: 
1.238     brouard    57:   Revision 1.237  2016/08/26 09:20:19  brouard
                     58:   Summary: to valgrind
                     59: 
1.237     brouard    60:   Revision 1.236  2016/08/25 10:50:18  brouard
                     61:   *** empty log message ***
                     62: 
1.236     brouard    63:   Revision 1.235  2016/08/25 06:59:23  brouard
                     64:   *** empty log message ***
                     65: 
1.235     brouard    66:   Revision 1.234  2016/08/23 16:51:20  brouard
                     67:   *** empty log message ***
                     68: 
1.234     brouard    69:   Revision 1.233  2016/08/23 07:40:50  brouard
                     70:   Summary: not working
                     71: 
1.233     brouard    72:   Revision 1.232  2016/08/22 14:20:21  brouard
                     73:   Summary: not working
                     74: 
1.232     brouard    75:   Revision 1.231  2016/08/22 07:17:15  brouard
                     76:   Summary: not working
                     77: 
1.231     brouard    78:   Revision 1.230  2016/08/22 06:55:53  brouard
                     79:   Summary: Not working
                     80: 
1.230     brouard    81:   Revision 1.229  2016/07/23 09:45:53  brouard
                     82:   Summary: Completing for func too
                     83: 
1.229     brouard    84:   Revision 1.228  2016/07/22 17:45:30  brouard
                     85:   Summary: Fixing some arrays, still debugging
                     86: 
1.227     brouard    87:   Revision 1.226  2016/07/12 18:42:34  brouard
                     88:   Summary: temp
                     89: 
1.226     brouard    90:   Revision 1.225  2016/07/12 08:40:03  brouard
                     91:   Summary: saving but not running
                     92: 
1.225     brouard    93:   Revision 1.224  2016/07/01 13:16:01  brouard
                     94:   Summary: Fixes
                     95: 
1.224     brouard    96:   Revision 1.223  2016/02/19 09:23:35  brouard
                     97:   Summary: temporary
                     98: 
1.223     brouard    99:   Revision 1.222  2016/02/17 08:14:50  brouard
                    100:   Summary: Probably last 0.98 stable version 0.98r6
                    101: 
1.222     brouard   102:   Revision 1.221  2016/02/15 23:35:36  brouard
                    103:   Summary: minor bug
                    104: 
1.220     brouard   105:   Revision 1.219  2016/02/15 00:48:12  brouard
                    106:   *** empty log message ***
                    107: 
1.219     brouard   108:   Revision 1.218  2016/02/12 11:29:23  brouard
                    109:   Summary: 0.99 Back projections
                    110: 
1.218     brouard   111:   Revision 1.217  2015/12/23 17:18:31  brouard
                    112:   Summary: Experimental backcast
                    113: 
1.217     brouard   114:   Revision 1.216  2015/12/18 17:32:11  brouard
                    115:   Summary: 0.98r4 Warning and status=-2
                    116: 
                    117:   Version 0.98r4 is now:
                    118:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    119:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    120:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    121: 
1.216     brouard   122:   Revision 1.215  2015/12/16 08:52:24  brouard
                    123:   Summary: 0.98r4 working
                    124: 
1.215     brouard   125:   Revision 1.214  2015/12/16 06:57:54  brouard
                    126:   Summary: temporary not working
                    127: 
1.214     brouard   128:   Revision 1.213  2015/12/11 18:22:17  brouard
                    129:   Summary: 0.98r4
                    130: 
1.213     brouard   131:   Revision 1.212  2015/11/21 12:47:24  brouard
                    132:   Summary: minor typo
                    133: 
1.212     brouard   134:   Revision 1.211  2015/11/21 12:41:11  brouard
                    135:   Summary: 0.98r3 with some graph of projected cross-sectional
                    136: 
                    137:   Author: Nicolas Brouard
                    138: 
1.211     brouard   139:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   140:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   141:   Summary: Adding ftolpl parameter
                    142:   Author: N Brouard
                    143: 
                    144:   We had difficulties to get smoothed confidence intervals. It was due
                    145:   to the period prevalence which wasn't computed accurately. The inner
                    146:   parameter ftolpl is now an outer parameter of the .imach parameter
                    147:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    148:   computation are long.
                    149: 
1.209     brouard   150:   Revision 1.208  2015/11/17 14:31:57  brouard
                    151:   Summary: temporary
                    152: 
1.208     brouard   153:   Revision 1.207  2015/10/27 17:36:57  brouard
                    154:   *** empty log message ***
                    155: 
1.207     brouard   156:   Revision 1.206  2015/10/24 07:14:11  brouard
                    157:   *** empty log message ***
                    158: 
1.206     brouard   159:   Revision 1.205  2015/10/23 15:50:53  brouard
                    160:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    161: 
1.205     brouard   162:   Revision 1.204  2015/10/01 16:20:26  brouard
                    163:   Summary: Some new graphs of contribution to likelihood
                    164: 
1.204     brouard   165:   Revision 1.203  2015/09/30 17:45:14  brouard
                    166:   Summary: looking at better estimation of the hessian
                    167: 
                    168:   Also a better criteria for convergence to the period prevalence And
                    169:   therefore adding the number of years needed to converge. (The
                    170:   prevalence in any alive state shold sum to one
                    171: 
1.203     brouard   172:   Revision 1.202  2015/09/22 19:45:16  brouard
                    173:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    174: 
1.202     brouard   175:   Revision 1.201  2015/09/15 17:34:58  brouard
                    176:   Summary: 0.98r0
                    177: 
                    178:   - Some new graphs like suvival functions
                    179:   - Some bugs fixed like model=1+age+V2.
                    180: 
1.201     brouard   181:   Revision 1.200  2015/09/09 16:53:55  brouard
                    182:   Summary: Big bug thanks to Flavia
                    183: 
                    184:   Even model=1+age+V2. did not work anymore
                    185: 
1.200     brouard   186:   Revision 1.199  2015/09/07 14:09:23  brouard
                    187:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    188: 
1.199     brouard   189:   Revision 1.198  2015/09/03 07:14:39  brouard
                    190:   Summary: 0.98q5 Flavia
                    191: 
1.198     brouard   192:   Revision 1.197  2015/09/01 18:24:39  brouard
                    193:   *** empty log message ***
                    194: 
1.197     brouard   195:   Revision 1.196  2015/08/18 23:17:52  brouard
                    196:   Summary: 0.98q5
                    197: 
1.196     brouard   198:   Revision 1.195  2015/08/18 16:28:39  brouard
                    199:   Summary: Adding a hack for testing purpose
                    200: 
                    201:   After reading the title, ftol and model lines, if the comment line has
                    202:   a q, starting with #q, the answer at the end of the run is quit. It
                    203:   permits to run test files in batch with ctest. The former workaround was
                    204:   $ echo q | imach foo.imach
                    205: 
1.195     brouard   206:   Revision 1.194  2015/08/18 13:32:00  brouard
                    207:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    208: 
1.194     brouard   209:   Revision 1.193  2015/08/04 07:17:42  brouard
                    210:   Summary: 0.98q4
                    211: 
1.193     brouard   212:   Revision 1.192  2015/07/16 16:49:02  brouard
                    213:   Summary: Fixing some outputs
                    214: 
1.192     brouard   215:   Revision 1.191  2015/07/14 10:00:33  brouard
                    216:   Summary: Some fixes
                    217: 
1.191     brouard   218:   Revision 1.190  2015/05/05 08:51:13  brouard
                    219:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    220: 
                    221:   Fix 1+age+.
                    222: 
1.190     brouard   223:   Revision 1.189  2015/04/30 14:45:16  brouard
                    224:   Summary: 0.98q2
                    225: 
1.189     brouard   226:   Revision 1.188  2015/04/30 08:27:53  brouard
                    227:   *** empty log message ***
                    228: 
1.188     brouard   229:   Revision 1.187  2015/04/29 09:11:15  brouard
                    230:   *** empty log message ***
                    231: 
1.187     brouard   232:   Revision 1.186  2015/04/23 12:01:52  brouard
                    233:   Summary: V1*age is working now, version 0.98q1
                    234: 
                    235:   Some codes had been disabled in order to simplify and Vn*age was
                    236:   working in the optimization phase, ie, giving correct MLE parameters,
                    237:   but, as usual, outputs were not correct and program core dumped.
                    238: 
1.186     brouard   239:   Revision 1.185  2015/03/11 13:26:42  brouard
                    240:   Summary: Inclusion of compile and links command line for Intel Compiler
                    241: 
1.185     brouard   242:   Revision 1.184  2015/03/11 11:52:39  brouard
                    243:   Summary: Back from Windows 8. Intel Compiler
                    244: 
1.184     brouard   245:   Revision 1.183  2015/03/10 20:34:32  brouard
                    246:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    247: 
                    248:   We use directest instead of original Powell test; probably no
                    249:   incidence on the results, but better justifications;
                    250:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    251:   wrong results.
                    252: 
1.183     brouard   253:   Revision 1.182  2015/02/12 08:19:57  brouard
                    254:   Summary: Trying to keep directest which seems simpler and more general
                    255:   Author: Nicolas Brouard
                    256: 
1.182     brouard   257:   Revision 1.181  2015/02/11 23:22:24  brouard
                    258:   Summary: Comments on Powell added
                    259: 
                    260:   Author:
                    261: 
1.181     brouard   262:   Revision 1.180  2015/02/11 17:33:45  brouard
                    263:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    264: 
1.180     brouard   265:   Revision 1.179  2015/01/04 09:57:06  brouard
                    266:   Summary: back to OS/X
                    267: 
1.179     brouard   268:   Revision 1.178  2015/01/04 09:35:48  brouard
                    269:   *** empty log message ***
                    270: 
1.178     brouard   271:   Revision 1.177  2015/01/03 18:40:56  brouard
                    272:   Summary: Still testing ilc32 on OSX
                    273: 
1.177     brouard   274:   Revision 1.176  2015/01/03 16:45:04  brouard
                    275:   *** empty log message ***
                    276: 
1.176     brouard   277:   Revision 1.175  2015/01/03 16:33:42  brouard
                    278:   *** empty log message ***
                    279: 
1.175     brouard   280:   Revision 1.174  2015/01/03 16:15:49  brouard
                    281:   Summary: Still in cross-compilation
                    282: 
1.174     brouard   283:   Revision 1.173  2015/01/03 12:06:26  brouard
                    284:   Summary: trying to detect cross-compilation
                    285: 
1.173     brouard   286:   Revision 1.172  2014/12/27 12:07:47  brouard
                    287:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    288: 
1.172     brouard   289:   Revision 1.171  2014/12/23 13:26:59  brouard
                    290:   Summary: Back from Visual C
                    291: 
                    292:   Still problem with utsname.h on Windows
                    293: 
1.171     brouard   294:   Revision 1.170  2014/12/23 11:17:12  brouard
                    295:   Summary: Cleaning some \%% back to %%
                    296: 
                    297:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    298: 
1.170     brouard   299:   Revision 1.169  2014/12/22 23:08:31  brouard
                    300:   Summary: 0.98p
                    301: 
                    302:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    303: 
1.169     brouard   304:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   305:   Summary: update
1.169     brouard   306: 
1.168     brouard   307:   Revision 1.167  2014/12/22 13:50:56  brouard
                    308:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    309: 
                    310:   Testing on Linux 64
                    311: 
1.167     brouard   312:   Revision 1.166  2014/12/22 11:40:47  brouard
                    313:   *** empty log message ***
                    314: 
1.166     brouard   315:   Revision 1.165  2014/12/16 11:20:36  brouard
                    316:   Summary: After compiling on Visual C
                    317: 
                    318:   * imach.c (Module): Merging 1.61 to 1.162
                    319: 
1.165     brouard   320:   Revision 1.164  2014/12/16 10:52:11  brouard
                    321:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    322: 
                    323:   * imach.c (Module): Merging 1.61 to 1.162
                    324: 
1.164     brouard   325:   Revision 1.163  2014/12/16 10:30:11  brouard
                    326:   * imach.c (Module): Merging 1.61 to 1.162
                    327: 
1.163     brouard   328:   Revision 1.162  2014/09/25 11:43:39  brouard
                    329:   Summary: temporary backup 0.99!
                    330: 
1.162     brouard   331:   Revision 1.1  2014/09/16 11:06:58  brouard
                    332:   Summary: With some code (wrong) for nlopt
                    333: 
                    334:   Author:
                    335: 
                    336:   Revision 1.161  2014/09/15 20:41:41  brouard
                    337:   Summary: Problem with macro SQR on Intel compiler
                    338: 
1.161     brouard   339:   Revision 1.160  2014/09/02 09:24:05  brouard
                    340:   *** empty log message ***
                    341: 
1.160     brouard   342:   Revision 1.159  2014/09/01 10:34:10  brouard
                    343:   Summary: WIN32
                    344:   Author: Brouard
                    345: 
1.159     brouard   346:   Revision 1.158  2014/08/27 17:11:51  brouard
                    347:   *** empty log message ***
                    348: 
1.158     brouard   349:   Revision 1.157  2014/08/27 16:26:55  brouard
                    350:   Summary: Preparing windows Visual studio version
                    351:   Author: Brouard
                    352: 
                    353:   In order to compile on Visual studio, time.h is now correct and time_t
                    354:   and tm struct should be used. difftime should be used but sometimes I
                    355:   just make the differences in raw time format (time(&now).
                    356:   Trying to suppress #ifdef LINUX
                    357:   Add xdg-open for __linux in order to open default browser.
                    358: 
1.157     brouard   359:   Revision 1.156  2014/08/25 20:10:10  brouard
                    360:   *** empty log message ***
                    361: 
1.156     brouard   362:   Revision 1.155  2014/08/25 18:32:34  brouard
                    363:   Summary: New compile, minor changes
                    364:   Author: Brouard
                    365: 
1.155     brouard   366:   Revision 1.154  2014/06/20 17:32:08  brouard
                    367:   Summary: Outputs now all graphs of convergence to period prevalence
                    368: 
1.154     brouard   369:   Revision 1.153  2014/06/20 16:45:46  brouard
                    370:   Summary: If 3 live state, convergence to period prevalence on same graph
                    371:   Author: Brouard
                    372: 
1.153     brouard   373:   Revision 1.152  2014/06/18 17:54:09  brouard
                    374:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    375: 
1.152     brouard   376:   Revision 1.151  2014/06/18 16:43:30  brouard
                    377:   *** empty log message ***
                    378: 
1.151     brouard   379:   Revision 1.150  2014/06/18 16:42:35  brouard
                    380:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    381:   Author: brouard
                    382: 
1.150     brouard   383:   Revision 1.149  2014/06/18 15:51:14  brouard
                    384:   Summary: Some fixes in parameter files errors
                    385:   Author: Nicolas Brouard
                    386: 
1.149     brouard   387:   Revision 1.148  2014/06/17 17:38:48  brouard
                    388:   Summary: Nothing new
                    389:   Author: Brouard
                    390: 
                    391:   Just a new packaging for OS/X version 0.98nS
                    392: 
1.148     brouard   393:   Revision 1.147  2014/06/16 10:33:11  brouard
                    394:   *** empty log message ***
                    395: 
1.147     brouard   396:   Revision 1.146  2014/06/16 10:20:28  brouard
                    397:   Summary: Merge
                    398:   Author: Brouard
                    399: 
                    400:   Merge, before building revised version.
                    401: 
1.146     brouard   402:   Revision 1.145  2014/06/10 21:23:15  brouard
                    403:   Summary: Debugging with valgrind
                    404:   Author: Nicolas Brouard
                    405: 
                    406:   Lot of changes in order to output the results with some covariates
                    407:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    408:   improve the code.
                    409:   No more memory valgrind error but a lot has to be done in order to
                    410:   continue the work of splitting the code into subroutines.
                    411:   Also, decodemodel has been improved. Tricode is still not
                    412:   optimal. nbcode should be improved. Documentation has been added in
                    413:   the source code.
                    414: 
1.144     brouard   415:   Revision 1.143  2014/01/26 09:45:38  brouard
                    416:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    417: 
                    418:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    419:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    420: 
1.143     brouard   421:   Revision 1.142  2014/01/26 03:57:36  brouard
                    422:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    423: 
                    424:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    425: 
1.142     brouard   426:   Revision 1.141  2014/01/26 02:42:01  brouard
                    427:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    428: 
1.141     brouard   429:   Revision 1.140  2011/09/02 10:37:54  brouard
                    430:   Summary: times.h is ok with mingw32 now.
                    431: 
1.140     brouard   432:   Revision 1.139  2010/06/14 07:50:17  brouard
                    433:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    434:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    435: 
1.139     brouard   436:   Revision 1.138  2010/04/30 18:19:40  brouard
                    437:   *** empty log message ***
                    438: 
1.138     brouard   439:   Revision 1.137  2010/04/29 18:11:38  brouard
                    440:   (Module): Checking covariates for more complex models
                    441:   than V1+V2. A lot of change to be done. Unstable.
                    442: 
1.137     brouard   443:   Revision 1.136  2010/04/26 20:30:53  brouard
                    444:   (Module): merging some libgsl code. Fixing computation
                    445:   of likelione (using inter/intrapolation if mle = 0) in order to
                    446:   get same likelihood as if mle=1.
                    447:   Some cleaning of code and comments added.
                    448: 
1.136     brouard   449:   Revision 1.135  2009/10/29 15:33:14  brouard
                    450:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    451: 
1.135     brouard   452:   Revision 1.134  2009/10/29 13:18:53  brouard
                    453:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    454: 
1.134     brouard   455:   Revision 1.133  2009/07/06 10:21:25  brouard
                    456:   just nforces
                    457: 
1.133     brouard   458:   Revision 1.132  2009/07/06 08:22:05  brouard
                    459:   Many tings
                    460: 
1.132     brouard   461:   Revision 1.131  2009/06/20 16:22:47  brouard
                    462:   Some dimensions resccaled
                    463: 
1.131     brouard   464:   Revision 1.130  2009/05/26 06:44:34  brouard
                    465:   (Module): Max Covariate is now set to 20 instead of 8. A
                    466:   lot of cleaning with variables initialized to 0. Trying to make
                    467:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    468: 
1.130     brouard   469:   Revision 1.129  2007/08/31 13:49:27  lievre
                    470:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    471: 
1.129     lievre    472:   Revision 1.128  2006/06/30 13:02:05  brouard
                    473:   (Module): Clarifications on computing e.j
                    474: 
1.128     brouard   475:   Revision 1.127  2006/04/28 18:11:50  brouard
                    476:   (Module): Yes the sum of survivors was wrong since
                    477:   imach-114 because nhstepm was no more computed in the age
                    478:   loop. Now we define nhstepma in the age loop.
                    479:   (Module): In order to speed up (in case of numerous covariates) we
                    480:   compute health expectancies (without variances) in a first step
                    481:   and then all the health expectancies with variances or standard
                    482:   deviation (needs data from the Hessian matrices) which slows the
                    483:   computation.
                    484:   In the future we should be able to stop the program is only health
                    485:   expectancies and graph are needed without standard deviations.
                    486: 
1.127     brouard   487:   Revision 1.126  2006/04/28 17:23:28  brouard
                    488:   (Module): Yes the sum of survivors was wrong since
                    489:   imach-114 because nhstepm was no more computed in the age
                    490:   loop. Now we define nhstepma in the age loop.
                    491:   Version 0.98h
                    492: 
1.126     brouard   493:   Revision 1.125  2006/04/04 15:20:31  lievre
                    494:   Errors in calculation of health expectancies. Age was not initialized.
                    495:   Forecasting file added.
                    496: 
                    497:   Revision 1.124  2006/03/22 17:13:53  lievre
                    498:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    499:   The log-likelihood is printed in the log file
                    500: 
                    501:   Revision 1.123  2006/03/20 10:52:43  brouard
                    502:   * imach.c (Module): <title> changed, corresponds to .htm file
                    503:   name. <head> headers where missing.
                    504: 
                    505:   * imach.c (Module): Weights can have a decimal point as for
                    506:   English (a comma might work with a correct LC_NUMERIC environment,
                    507:   otherwise the weight is truncated).
                    508:   Modification of warning when the covariates values are not 0 or
                    509:   1.
                    510:   Version 0.98g
                    511: 
                    512:   Revision 1.122  2006/03/20 09:45:41  brouard
                    513:   (Module): Weights can have a decimal point as for
                    514:   English (a comma might work with a correct LC_NUMERIC environment,
                    515:   otherwise the weight is truncated).
                    516:   Modification of warning when the covariates values are not 0 or
                    517:   1.
                    518:   Version 0.98g
                    519: 
                    520:   Revision 1.121  2006/03/16 17:45:01  lievre
                    521:   * imach.c (Module): Comments concerning covariates added
                    522: 
                    523:   * imach.c (Module): refinements in the computation of lli if
                    524:   status=-2 in order to have more reliable computation if stepm is
                    525:   not 1 month. Version 0.98f
                    526: 
                    527:   Revision 1.120  2006/03/16 15:10:38  lievre
                    528:   (Module): refinements in the computation of lli if
                    529:   status=-2 in order to have more reliable computation if stepm is
                    530:   not 1 month. Version 0.98f
                    531: 
                    532:   Revision 1.119  2006/03/15 17:42:26  brouard
                    533:   (Module): Bug if status = -2, the loglikelihood was
                    534:   computed as likelihood omitting the logarithm. Version O.98e
                    535: 
                    536:   Revision 1.118  2006/03/14 18:20:07  brouard
                    537:   (Module): varevsij Comments added explaining the second
                    538:   table of variances if popbased=1 .
                    539:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    540:   (Module): Function pstamp added
                    541:   (Module): Version 0.98d
                    542: 
                    543:   Revision 1.117  2006/03/14 17:16:22  brouard
                    544:   (Module): varevsij Comments added explaining the second
                    545:   table of variances if popbased=1 .
                    546:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    547:   (Module): Function pstamp added
                    548:   (Module): Version 0.98d
                    549: 
                    550:   Revision 1.116  2006/03/06 10:29:27  brouard
                    551:   (Module): Variance-covariance wrong links and
                    552:   varian-covariance of ej. is needed (Saito).
                    553: 
                    554:   Revision 1.115  2006/02/27 12:17:45  brouard
                    555:   (Module): One freematrix added in mlikeli! 0.98c
                    556: 
                    557:   Revision 1.114  2006/02/26 12:57:58  brouard
                    558:   (Module): Some improvements in processing parameter
                    559:   filename with strsep.
                    560: 
                    561:   Revision 1.113  2006/02/24 14:20:24  brouard
                    562:   (Module): Memory leaks checks with valgrind and:
                    563:   datafile was not closed, some imatrix were not freed and on matrix
                    564:   allocation too.
                    565: 
                    566:   Revision 1.112  2006/01/30 09:55:26  brouard
                    567:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    568: 
                    569:   Revision 1.111  2006/01/25 20:38:18  brouard
                    570:   (Module): Lots of cleaning and bugs added (Gompertz)
                    571:   (Module): Comments can be added in data file. Missing date values
                    572:   can be a simple dot '.'.
                    573: 
                    574:   Revision 1.110  2006/01/25 00:51:50  brouard
                    575:   (Module): Lots of cleaning and bugs added (Gompertz)
                    576: 
                    577:   Revision 1.109  2006/01/24 19:37:15  brouard
                    578:   (Module): Comments (lines starting with a #) are allowed in data.
                    579: 
                    580:   Revision 1.108  2006/01/19 18:05:42  lievre
                    581:   Gnuplot problem appeared...
                    582:   To be fixed
                    583: 
                    584:   Revision 1.107  2006/01/19 16:20:37  brouard
                    585:   Test existence of gnuplot in imach path
                    586: 
                    587:   Revision 1.106  2006/01/19 13:24:36  brouard
                    588:   Some cleaning and links added in html output
                    589: 
                    590:   Revision 1.105  2006/01/05 20:23:19  lievre
                    591:   *** empty log message ***
                    592: 
                    593:   Revision 1.104  2005/09/30 16:11:43  lievre
                    594:   (Module): sump fixed, loop imx fixed, and simplifications.
                    595:   (Module): If the status is missing at the last wave but we know
                    596:   that the person is alive, then we can code his/her status as -2
                    597:   (instead of missing=-1 in earlier versions) and his/her
                    598:   contributions to the likelihood is 1 - Prob of dying from last
                    599:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    600:   the healthy state at last known wave). Version is 0.98
                    601: 
                    602:   Revision 1.103  2005/09/30 15:54:49  lievre
                    603:   (Module): sump fixed, loop imx fixed, and simplifications.
                    604: 
                    605:   Revision 1.102  2004/09/15 17:31:30  brouard
                    606:   Add the possibility to read data file including tab characters.
                    607: 
                    608:   Revision 1.101  2004/09/15 10:38:38  brouard
                    609:   Fix on curr_time
                    610: 
                    611:   Revision 1.100  2004/07/12 18:29:06  brouard
                    612:   Add version for Mac OS X. Just define UNIX in Makefile
                    613: 
                    614:   Revision 1.99  2004/06/05 08:57:40  brouard
                    615:   *** empty log message ***
                    616: 
                    617:   Revision 1.98  2004/05/16 15:05:56  brouard
                    618:   New version 0.97 . First attempt to estimate force of mortality
                    619:   directly from the data i.e. without the need of knowing the health
                    620:   state at each age, but using a Gompertz model: log u =a + b*age .
                    621:   This is the basic analysis of mortality and should be done before any
                    622:   other analysis, in order to test if the mortality estimated from the
                    623:   cross-longitudinal survey is different from the mortality estimated
                    624:   from other sources like vital statistic data.
                    625: 
                    626:   The same imach parameter file can be used but the option for mle should be -3.
                    627: 
1.133     brouard   628:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   629:   former routines in order to include the new code within the former code.
                    630: 
                    631:   The output is very simple: only an estimate of the intercept and of
                    632:   the slope with 95% confident intervals.
                    633: 
                    634:   Current limitations:
                    635:   A) Even if you enter covariates, i.e. with the
                    636:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    637:   B) There is no computation of Life Expectancy nor Life Table.
                    638: 
                    639:   Revision 1.97  2004/02/20 13:25:42  lievre
                    640:   Version 0.96d. Population forecasting command line is (temporarily)
                    641:   suppressed.
                    642: 
                    643:   Revision 1.96  2003/07/15 15:38:55  brouard
                    644:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    645:   rewritten within the same printf. Workaround: many printfs.
                    646: 
                    647:   Revision 1.95  2003/07/08 07:54:34  brouard
                    648:   * imach.c (Repository):
                    649:   (Repository): Using imachwizard code to output a more meaningful covariance
                    650:   matrix (cov(a12,c31) instead of numbers.
                    651: 
                    652:   Revision 1.94  2003/06/27 13:00:02  brouard
                    653:   Just cleaning
                    654: 
                    655:   Revision 1.93  2003/06/25 16:33:55  brouard
                    656:   (Module): On windows (cygwin) function asctime_r doesn't
                    657:   exist so I changed back to asctime which exists.
                    658:   (Module): Version 0.96b
                    659: 
                    660:   Revision 1.92  2003/06/25 16:30:45  brouard
                    661:   (Module): On windows (cygwin) function asctime_r doesn't
                    662:   exist so I changed back to asctime which exists.
                    663: 
                    664:   Revision 1.91  2003/06/25 15:30:29  brouard
                    665:   * imach.c (Repository): Duplicated warning errors corrected.
                    666:   (Repository): Elapsed time after each iteration is now output. It
                    667:   helps to forecast when convergence will be reached. Elapsed time
                    668:   is stamped in powell.  We created a new html file for the graphs
                    669:   concerning matrix of covariance. It has extension -cov.htm.
                    670: 
                    671:   Revision 1.90  2003/06/24 12:34:15  brouard
                    672:   (Module): Some bugs corrected for windows. Also, when
                    673:   mle=-1 a template is output in file "or"mypar.txt with the design
                    674:   of the covariance matrix to be input.
                    675: 
                    676:   Revision 1.89  2003/06/24 12:30:52  brouard
                    677:   (Module): Some bugs corrected for windows. Also, when
                    678:   mle=-1 a template is output in file "or"mypar.txt with the design
                    679:   of the covariance matrix to be input.
                    680: 
                    681:   Revision 1.88  2003/06/23 17:54:56  brouard
                    682:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    683: 
                    684:   Revision 1.87  2003/06/18 12:26:01  brouard
                    685:   Version 0.96
                    686: 
                    687:   Revision 1.86  2003/06/17 20:04:08  brouard
                    688:   (Module): Change position of html and gnuplot routines and added
                    689:   routine fileappend.
                    690: 
                    691:   Revision 1.85  2003/06/17 13:12:43  brouard
                    692:   * imach.c (Repository): Check when date of death was earlier that
                    693:   current date of interview. It may happen when the death was just
                    694:   prior to the death. In this case, dh was negative and likelihood
                    695:   was wrong (infinity). We still send an "Error" but patch by
                    696:   assuming that the date of death was just one stepm after the
                    697:   interview.
                    698:   (Repository): Because some people have very long ID (first column)
                    699:   we changed int to long in num[] and we added a new lvector for
                    700:   memory allocation. But we also truncated to 8 characters (left
                    701:   truncation)
                    702:   (Repository): No more line truncation errors.
                    703: 
                    704:   Revision 1.84  2003/06/13 21:44:43  brouard
                    705:   * imach.c (Repository): Replace "freqsummary" at a correct
                    706:   place. It differs from routine "prevalence" which may be called
                    707:   many times. Probs is memory consuming and must be used with
                    708:   parcimony.
                    709:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    710: 
                    711:   Revision 1.83  2003/06/10 13:39:11  lievre
                    712:   *** empty log message ***
                    713: 
                    714:   Revision 1.82  2003/06/05 15:57:20  brouard
                    715:   Add log in  imach.c and  fullversion number is now printed.
                    716: 
                    717: */
                    718: /*
                    719:    Interpolated Markov Chain
                    720: 
                    721:   Short summary of the programme:
                    722:   
1.227     brouard   723:   This program computes Healthy Life Expectancies or State-specific
                    724:   (if states aren't health statuses) Expectancies from
                    725:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    726: 
                    727:   -1- a first survey ("cross") where individuals from different ages
                    728:   are interviewed on their health status or degree of disability (in
                    729:   the case of a health survey which is our main interest)
                    730: 
                    731:   -2- at least a second wave of interviews ("longitudinal") which
                    732:   measure each change (if any) in individual health status.  Health
                    733:   expectancies are computed from the time spent in each health state
                    734:   according to a model. More health states you consider, more time is
                    735:   necessary to reach the Maximum Likelihood of the parameters involved
                    736:   in the model.  The simplest model is the multinomial logistic model
                    737:   where pij is the probability to be observed in state j at the second
                    738:   wave conditional to be observed in state i at the first
                    739:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    740:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    741:   have a more complex model than "constant and age", you should modify
                    742:   the program where the markup *Covariates have to be included here
                    743:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   744:   convergence.
                    745: 
                    746:   The advantage of this computer programme, compared to a simple
                    747:   multinomial logistic model, is clear when the delay between waves is not
                    748:   identical for each individual. Also, if a individual missed an
                    749:   intermediate interview, the information is lost, but taken into
                    750:   account using an interpolation or extrapolation.  
                    751: 
                    752:   hPijx is the probability to be observed in state i at age x+h
                    753:   conditional to the observed state i at age x. The delay 'h' can be
                    754:   split into an exact number (nh*stepm) of unobserved intermediate
                    755:   states. This elementary transition (by month, quarter,
                    756:   semester or year) is modelled as a multinomial logistic.  The hPx
                    757:   matrix is simply the matrix product of nh*stepm elementary matrices
                    758:   and the contribution of each individual to the likelihood is simply
                    759:   hPijx.
                    760: 
                    761:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   762:   of the life expectancies. It also computes the period (stable) prevalence.
                    763: 
                    764: Back prevalence and projections:
1.227     brouard   765: 
                    766:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    767:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    768:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    769:    mobilavproj)
                    770: 
                    771:     Computes the back prevalence limit for any combination of
                    772:     covariate values k at any age between ageminpar and agemaxpar and
                    773:     returns it in **bprlim. In the loops,
                    774: 
                    775:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    776:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    777: 
                    778:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   779:    Computes for any combination of covariates k and any age between bage and fage 
                    780:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    781:                        oldm=oldms;savm=savms;
1.227     brouard   782: 
                    783:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);
1.218     brouard   784:      Computes the transition matrix starting at age 'age' over
                    785:      'nhstepm*hstepm*stepm' months (i.e. until
                    786:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   787:      nhstepm*hstepm matrices. 
                    788: 
                    789:      Returns p3mat[i][j][h] after calling
                    790:      p3mat[i][j][h]=matprod2(newm,
                    791:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    792:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    793:      oldm);
1.226     brouard   794: 
                    795: Important routines
                    796: 
                    797: - func (or funcone), computes logit (pij) distinguishing
                    798:   o fixed variables (single or product dummies or quantitative);
                    799:   o varying variables by:
                    800:    (1) wave (single, product dummies, quantitative), 
                    801:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    802:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    803:        % varying dummy (not done) or quantitative (not done);
                    804: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    805:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    806: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    807:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    808:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   809: 
1.226     brouard   810: 
                    811:   
1.133     brouard   812:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    813:            Institut national d'études démographiques, Paris.
1.126     brouard   814:   This software have been partly granted by Euro-REVES, a concerted action
                    815:   from the European Union.
                    816:   It is copyrighted identically to a GNU software product, ie programme and
                    817:   software can be distributed freely for non commercial use. Latest version
                    818:   can be accessed at http://euroreves.ined.fr/imach .
                    819: 
                    820:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    821:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    822:   
                    823:   **********************************************************************/
                    824: /*
                    825:   main
                    826:   read parameterfile
                    827:   read datafile
                    828:   concatwav
                    829:   freqsummary
                    830:   if (mle >= 1)
                    831:     mlikeli
                    832:   print results files
                    833:   if mle==1 
                    834:      computes hessian
                    835:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    836:       begin-prev-date,...
                    837:   open gnuplot file
                    838:   open html file
1.145     brouard   839:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    840:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    841:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    842:     freexexit2 possible for memory heap.
                    843: 
                    844:   h Pij x                         | pij_nom  ficrestpij
                    845:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    846:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    847:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    848: 
                    849:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    850:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    851:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    852:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    853:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    854: 
1.126     brouard   855:   forecasting if prevfcast==1 prevforecast call prevalence()
                    856:   health expectancies
                    857:   Variance-covariance of DFLE
                    858:   prevalence()
                    859:    movingaverage()
                    860:   varevsij() 
                    861:   if popbased==1 varevsij(,popbased)
                    862:   total life expectancies
                    863:   Variance of period (stable) prevalence
                    864:  end
                    865: */
                    866: 
1.187     brouard   867: /* #define DEBUG */
                    868: /* #define DEBUGBRENT */
1.203     brouard   869: /* #define DEBUGLINMIN */
                    870: /* #define DEBUGHESS */
                    871: #define DEBUGHESSIJ
1.224     brouard   872: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   873: #define POWELL /* Instead of NLOPT */
1.224     brouard   874: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   875: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    876: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   877: 
                    878: #include <math.h>
                    879: #include <stdio.h>
                    880: #include <stdlib.h>
                    881: #include <string.h>
1.226     brouard   882: #include <ctype.h>
1.159     brouard   883: 
                    884: #ifdef _WIN32
                    885: #include <io.h>
1.172     brouard   886: #include <windows.h>
                    887: #include <tchar.h>
1.159     brouard   888: #else
1.126     brouard   889: #include <unistd.h>
1.159     brouard   890: #endif
1.126     brouard   891: 
                    892: #include <limits.h>
                    893: #include <sys/types.h>
1.171     brouard   894: 
                    895: #if defined(__GNUC__)
                    896: #include <sys/utsname.h> /* Doesn't work on Windows */
                    897: #endif
                    898: 
1.126     brouard   899: #include <sys/stat.h>
                    900: #include <errno.h>
1.159     brouard   901: /* extern int errno; */
1.126     brouard   902: 
1.157     brouard   903: /* #ifdef LINUX */
                    904: /* #include <time.h> */
                    905: /* #include "timeval.h" */
                    906: /* #else */
                    907: /* #include <sys/time.h> */
                    908: /* #endif */
                    909: 
1.126     brouard   910: #include <time.h>
                    911: 
1.136     brouard   912: #ifdef GSL
                    913: #include <gsl/gsl_errno.h>
                    914: #include <gsl/gsl_multimin.h>
                    915: #endif
                    916: 
1.167     brouard   917: 
1.162     brouard   918: #ifdef NLOPT
                    919: #include <nlopt.h>
                    920: typedef struct {
                    921:   double (* function)(double [] );
                    922: } myfunc_data ;
                    923: #endif
                    924: 
1.126     brouard   925: /* #include <libintl.h> */
                    926: /* #define _(String) gettext (String) */
                    927: 
1.251     brouard   928: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   929: 
                    930: #define GNUPLOTPROGRAM "gnuplot"
                    931: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    932: #define FILENAMELENGTH 132
                    933: 
                    934: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    935: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    936: 
1.144     brouard   937: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    938: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   939: 
                    940: #define NINTERVMAX 8
1.144     brouard   941: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    942: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    943: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   944: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   945: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    946: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   947: #define MAXN 20000
1.144     brouard   948: #define YEARM 12. /**< Number of months per year */
1.218     brouard   949: /* #define AGESUP 130 */
                    950: #define AGESUP 150
                    951: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard   952: #define AGEBASE 40
1.194     brouard   953: #define AGEOVERFLOW 1.e20
1.164     brouard   954: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard   955: #ifdef _WIN32
                    956: #define DIRSEPARATOR '\\'
                    957: #define CHARSEPARATOR "\\"
                    958: #define ODIRSEPARATOR '/'
                    959: #else
1.126     brouard   960: #define DIRSEPARATOR '/'
                    961: #define CHARSEPARATOR "/"
                    962: #define ODIRSEPARATOR '\\'
                    963: #endif
                    964: 
1.255   ! brouard   965: /* $Id: imach.c,v 1.254 2017/03/08 07:13:00 brouard Exp $ */
1.126     brouard   966: /* $State: Exp $ */
1.196     brouard   967: #include "version.h"
                    968: char version[]=__IMACH_VERSION__;
1.224     brouard   969: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.255   ! brouard   970: char fullversion[]="$Revision: 1.254 $ $Date: 2017/03/08 07:13:00 $"; 
1.126     brouard   971: char strstart[80];
                    972: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard   973: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard   974: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard   975: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                    976: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                    977: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard   978: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                    979: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard   980: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                    981: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                    982: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard   983: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                    984: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard   985: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard   986: int nsd=0; /**< Total number of single dummy variables (output) */
                    987: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard   988: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard   989: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard   990: int ntveff=0; /**< ntveff number of effective time varying variables */
                    991: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard   992: int cptcov=0; /* Working variable */
1.218     brouard   993: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard   994: int npar=NPARMAX;
                    995: int nlstate=2; /* Number of live states */
                    996: int ndeath=1; /* Number of dead states */
1.130     brouard   997: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard   998: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard   999: int popbased=0;
                   1000: 
                   1001: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1002: int maxwav=0; /* Maxim number of waves */
                   1003: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1004: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1005: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1006:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1007: int mle=1, weightopt=0;
1.126     brouard  1008: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1009: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1010: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1011:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1012: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1013: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1014: 
1.130     brouard  1015: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1016: double **matprod2(); /* test */
1.126     brouard  1017: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1018: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1019: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1020: 
1.136     brouard  1021: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1022: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1023: FILE *ficlog, *ficrespow;
1.130     brouard  1024: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1025: double fretone; /* Only one call to likelihood */
1.130     brouard  1026: long ipmx=0; /* Number of contributions */
1.126     brouard  1027: double sw; /* Sum of weights */
                   1028: char filerespow[FILENAMELENGTH];
                   1029: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1030: FILE *ficresilk;
                   1031: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1032: FILE *ficresprobmorprev;
                   1033: FILE *fichtm, *fichtmcov; /* Html File */
                   1034: FILE *ficreseij;
                   1035: char filerese[FILENAMELENGTH];
                   1036: FILE *ficresstdeij;
                   1037: char fileresstde[FILENAMELENGTH];
                   1038: FILE *ficrescveij;
                   1039: char filerescve[FILENAMELENGTH];
                   1040: FILE  *ficresvij;
                   1041: char fileresv[FILENAMELENGTH];
                   1042: FILE  *ficresvpl;
                   1043: char fileresvpl[FILENAMELENGTH];
                   1044: char title[MAXLINE];
1.234     brouard  1045: char model[MAXLINE]; /**< The model line */
1.217     brouard  1046: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1047: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1048: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1049: char command[FILENAMELENGTH];
                   1050: int  outcmd=0;
                   1051: 
1.217     brouard  1052: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1053: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1054: char filelog[FILENAMELENGTH]; /* Log file */
                   1055: char filerest[FILENAMELENGTH];
                   1056: char fileregp[FILENAMELENGTH];
                   1057: char popfile[FILENAMELENGTH];
                   1058: 
                   1059: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1060: 
1.157     brouard  1061: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1062: /* struct timezone tzp; */
                   1063: /* extern int gettimeofday(); */
                   1064: struct tm tml, *gmtime(), *localtime();
                   1065: 
                   1066: extern time_t time();
                   1067: 
                   1068: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1069: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1070: struct tm tm;
                   1071: 
1.126     brouard  1072: char strcurr[80], strfor[80];
                   1073: 
                   1074: char *endptr;
                   1075: long lval;
                   1076: double dval;
                   1077: 
                   1078: #define NR_END 1
                   1079: #define FREE_ARG char*
                   1080: #define FTOL 1.0e-10
                   1081: 
                   1082: #define NRANSI 
1.240     brouard  1083: #define ITMAX 200
                   1084: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1085: 
                   1086: #define TOL 2.0e-4 
                   1087: 
                   1088: #define CGOLD 0.3819660 
                   1089: #define ZEPS 1.0e-10 
                   1090: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1091: 
                   1092: #define GOLD 1.618034 
                   1093: #define GLIMIT 100.0 
                   1094: #define TINY 1.0e-20 
                   1095: 
                   1096: static double maxarg1,maxarg2;
                   1097: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1098: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1099:   
                   1100: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1101: #define rint(a) floor(a+0.5)
1.166     brouard  1102: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1103: #define mytinydouble 1.0e-16
1.166     brouard  1104: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1105: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1106: /* static double dsqrarg; */
                   1107: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1108: static double sqrarg;
                   1109: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1110: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1111: int agegomp= AGEGOMP;
                   1112: 
                   1113: int imx; 
                   1114: int stepm=1;
                   1115: /* Stepm, step in month: minimum step interpolation*/
                   1116: 
                   1117: int estepm;
                   1118: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1119: 
                   1120: int m,nb;
                   1121: long *num;
1.197     brouard  1122: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1123: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1124:                   covariate for which somebody answered excluding 
                   1125:                   undefined. Usually 2: 0 and 1. */
                   1126: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1127:                             covariate for which somebody answered including 
                   1128:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1129: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1130: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1131: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1132: double *ageexmed,*agecens;
                   1133: double dateintmean=0;
                   1134: 
                   1135: double *weight;
                   1136: int **s; /* Status */
1.141     brouard  1137: double *agedc;
1.145     brouard  1138: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1139:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1140:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.225     brouard  1141: double **coqvar; /* Fixed quantitative covariate iqv */
                   1142: double ***cotvar; /* Time varying covariate itv */
                   1143: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1144: double  idx; 
                   1145: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1146: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1147: /*k          1  2   3   4     5    6    7     8    9 */
                   1148: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1149: /* Tndvar[k]    1   2   3               4          5 */
                   1150: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1151: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1152: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1153: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1154: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1155: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1156: /* Tprod[i]=k           4               7            */
                   1157: /* Tage[i]=k                  5               8      */
                   1158: /* */
                   1159: /* Type                    */
                   1160: /* V         1  2  3  4  5 */
                   1161: /*           F  F  V  V  V */
                   1162: /*           D  Q  D  D  Q */
                   1163: /*                         */
                   1164: int *TvarsD;
                   1165: int *TvarsDind;
                   1166: int *TvarsQ;
                   1167: int *TvarsQind;
                   1168: 
1.235     brouard  1169: #define MAXRESULTLINES 10
                   1170: int nresult=0;
                   1171: int TKresult[MAXRESULTLINES];
1.237     brouard  1172: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1173: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1174: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1175: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1176: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1177: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1178: 
1.234     brouard  1179: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1180: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1181: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1182: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1183: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1184: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1185: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1186: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1187: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1188: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1189: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1190: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1191: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1192: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1193: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1194: 
1.230     brouard  1195: int *Tvarsel; /**< Selected covariates for output */
                   1196: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1197: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1198: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1199: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1200: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1201: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1202: int *Tage;
1.227     brouard  1203: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1204: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1205: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1206: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1207: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1208: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1209: int **Tvard;
                   1210: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1211: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1212: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1213:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1214:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1215: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1216: double *lsurv, *lpop, *tpop;
                   1217: 
1.231     brouard  1218: #define FD 1; /* Fixed dummy covariate */
                   1219: #define FQ 2; /* Fixed quantitative covariate */
                   1220: #define FP 3; /* Fixed product covariate */
                   1221: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1222: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1223: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1224: #define VD 10; /* Varying dummy covariate */
                   1225: #define VQ 11; /* Varying quantitative covariate */
                   1226: #define VP 12; /* Varying product covariate */
                   1227: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1228: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1229: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1230: #define APFD 16; /* Age product * fixed dummy covariate */
                   1231: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1232: #define APVD 18; /* Age product * varying dummy covariate */
                   1233: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1234: 
                   1235: #define FTYPE 1; /* Fixed covariate */
                   1236: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1237: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1238: 
                   1239: struct kmodel{
                   1240:        int maintype; /* main type */
                   1241:        int subtype; /* subtype */
                   1242: };
                   1243: struct kmodel modell[NCOVMAX];
                   1244: 
1.143     brouard  1245: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1246: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1247: 
                   1248: /**************** split *************************/
                   1249: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1250: {
                   1251:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1252:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1253:   */ 
                   1254:   char *ss;                            /* pointer */
1.186     brouard  1255:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1256: 
                   1257:   l1 = strlen(path );                  /* length of path */
                   1258:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1259:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1260:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1261:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1262:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1263:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1264:     /* get current working directory */
                   1265:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1266: #ifdef WIN32
                   1267:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1268: #else
                   1269:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1270: #endif
1.126     brouard  1271:       return( GLOCK_ERROR_GETCWD );
                   1272:     }
                   1273:     /* got dirc from getcwd*/
                   1274:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1275:   } else {                             /* strip directory from path */
1.126     brouard  1276:     ss++;                              /* after this, the filename */
                   1277:     l2 = strlen( ss );                 /* length of filename */
                   1278:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1279:     strcpy( name, ss );                /* save file name */
                   1280:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1281:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1282:     printf(" DIRC2 = %s \n",dirc);
                   1283:   }
                   1284:   /* We add a separator at the end of dirc if not exists */
                   1285:   l1 = strlen( dirc );                 /* length of directory */
                   1286:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1287:     dirc[l1] =  DIRSEPARATOR;
                   1288:     dirc[l1+1] = 0; 
                   1289:     printf(" DIRC3 = %s \n",dirc);
                   1290:   }
                   1291:   ss = strrchr( name, '.' );           /* find last / */
                   1292:   if (ss >0){
                   1293:     ss++;
                   1294:     strcpy(ext,ss);                    /* save extension */
                   1295:     l1= strlen( name);
                   1296:     l2= strlen(ss)+1;
                   1297:     strncpy( finame, name, l1-l2);
                   1298:     finame[l1-l2]= 0;
                   1299:   }
                   1300: 
                   1301:   return( 0 );                         /* we're done */
                   1302: }
                   1303: 
                   1304: 
                   1305: /******************************************/
                   1306: 
                   1307: void replace_back_to_slash(char *s, char*t)
                   1308: {
                   1309:   int i;
                   1310:   int lg=0;
                   1311:   i=0;
                   1312:   lg=strlen(t);
                   1313:   for(i=0; i<= lg; i++) {
                   1314:     (s[i] = t[i]);
                   1315:     if (t[i]== '\\') s[i]='/';
                   1316:   }
                   1317: }
                   1318: 
1.132     brouard  1319: char *trimbb(char *out, char *in)
1.137     brouard  1320: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1321:   char *s;
                   1322:   s=out;
                   1323:   while (*in != '\0'){
1.137     brouard  1324:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1325:       in++;
                   1326:     }
                   1327:     *out++ = *in++;
                   1328:   }
                   1329:   *out='\0';
                   1330:   return s;
                   1331: }
                   1332: 
1.187     brouard  1333: /* char *substrchaine(char *out, char *in, char *chain) */
                   1334: /* { */
                   1335: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1336: /*   char *s, *t; */
                   1337: /*   t=in;s=out; */
                   1338: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1339: /*     *out++ = *in++; */
                   1340: /*   } */
                   1341: 
                   1342: /*   /\* *in matches *chain *\/ */
                   1343: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1344: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1345: /*   } */
                   1346: /*   in--; chain--; */
                   1347: /*   while ( (*in != '\0')){ */
                   1348: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1349: /*     *out++ = *in++; */
                   1350: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1351: /*   } */
                   1352: /*   *out='\0'; */
                   1353: /*   out=s; */
                   1354: /*   return out; */
                   1355: /* } */
                   1356: char *substrchaine(char *out, char *in, char *chain)
                   1357: {
                   1358:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1359:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1360: 
                   1361:   char *strloc;
                   1362: 
                   1363:   strcpy (out, in); 
                   1364:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1365:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1366:   if(strloc != NULL){ 
                   1367:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1368:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1369:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1370:   }
                   1371:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1372:   return out;
                   1373: }
                   1374: 
                   1375: 
1.145     brouard  1376: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1377: {
1.187     brouard  1378:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1379:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1380:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1381:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1382:   */
1.160     brouard  1383:   char *s, *t;
1.145     brouard  1384:   t=in;s=in;
                   1385:   while ((*in != occ) && (*in != '\0')){
                   1386:     *alocc++ = *in++;
                   1387:   }
                   1388:   if( *in == occ){
                   1389:     *(alocc)='\0';
                   1390:     s=++in;
                   1391:   }
                   1392:  
                   1393:   if (s == t) {/* occ not found */
                   1394:     *(alocc-(in-s))='\0';
                   1395:     in=s;
                   1396:   }
                   1397:   while ( *in != '\0'){
                   1398:     *blocc++ = *in++;
                   1399:   }
                   1400: 
                   1401:   *blocc='\0';
                   1402:   return t;
                   1403: }
1.137     brouard  1404: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1405: {
1.187     brouard  1406:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1407:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1408:      gives blocc="abcdef2ghi" and alocc="j".
                   1409:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1410:   */
                   1411:   char *s, *t;
                   1412:   t=in;s=in;
                   1413:   while (*in != '\0'){
                   1414:     while( *in == occ){
                   1415:       *blocc++ = *in++;
                   1416:       s=in;
                   1417:     }
                   1418:     *blocc++ = *in++;
                   1419:   }
                   1420:   if (s == t) /* occ not found */
                   1421:     *(blocc-(in-s))='\0';
                   1422:   else
                   1423:     *(blocc-(in-s)-1)='\0';
                   1424:   in=s;
                   1425:   while ( *in != '\0'){
                   1426:     *alocc++ = *in++;
                   1427:   }
                   1428: 
                   1429:   *alocc='\0';
                   1430:   return s;
                   1431: }
                   1432: 
1.126     brouard  1433: int nbocc(char *s, char occ)
                   1434: {
                   1435:   int i,j=0;
                   1436:   int lg=20;
                   1437:   i=0;
                   1438:   lg=strlen(s);
                   1439:   for(i=0; i<= lg; i++) {
1.234     brouard  1440:     if  (s[i] == occ ) j++;
1.126     brouard  1441:   }
                   1442:   return j;
                   1443: }
                   1444: 
1.137     brouard  1445: /* void cutv(char *u,char *v, char*t, char occ) */
                   1446: /* { */
                   1447: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1448: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1449: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1450: /*   int i,lg,j,p=0; */
                   1451: /*   i=0; */
                   1452: /*   lg=strlen(t); */
                   1453: /*   for(j=0; j<=lg-1; j++) { */
                   1454: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1455: /*   } */
1.126     brouard  1456: 
1.137     brouard  1457: /*   for(j=0; j<p; j++) { */
                   1458: /*     (u[j] = t[j]); */
                   1459: /*   } */
                   1460: /*      u[p]='\0'; */
1.126     brouard  1461: 
1.137     brouard  1462: /*    for(j=0; j<= lg; j++) { */
                   1463: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1464: /*   } */
                   1465: /* } */
1.126     brouard  1466: 
1.160     brouard  1467: #ifdef _WIN32
                   1468: char * strsep(char **pp, const char *delim)
                   1469: {
                   1470:   char *p, *q;
                   1471:          
                   1472:   if ((p = *pp) == NULL)
                   1473:     return 0;
                   1474:   if ((q = strpbrk (p, delim)) != NULL)
                   1475:   {
                   1476:     *pp = q + 1;
                   1477:     *q = '\0';
                   1478:   }
                   1479:   else
                   1480:     *pp = 0;
                   1481:   return p;
                   1482: }
                   1483: #endif
                   1484: 
1.126     brouard  1485: /********************** nrerror ********************/
                   1486: 
                   1487: void nrerror(char error_text[])
                   1488: {
                   1489:   fprintf(stderr,"ERREUR ...\n");
                   1490:   fprintf(stderr,"%s\n",error_text);
                   1491:   exit(EXIT_FAILURE);
                   1492: }
                   1493: /*********************** vector *******************/
                   1494: double *vector(int nl, int nh)
                   1495: {
                   1496:   double *v;
                   1497:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1498:   if (!v) nrerror("allocation failure in vector");
                   1499:   return v-nl+NR_END;
                   1500: }
                   1501: 
                   1502: /************************ free vector ******************/
                   1503: void free_vector(double*v, int nl, int nh)
                   1504: {
                   1505:   free((FREE_ARG)(v+nl-NR_END));
                   1506: }
                   1507: 
                   1508: /************************ivector *******************************/
                   1509: int *ivector(long nl,long nh)
                   1510: {
                   1511:   int *v;
                   1512:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1513:   if (!v) nrerror("allocation failure in ivector");
                   1514:   return v-nl+NR_END;
                   1515: }
                   1516: 
                   1517: /******************free ivector **************************/
                   1518: void free_ivector(int *v, long nl, long nh)
                   1519: {
                   1520:   free((FREE_ARG)(v+nl-NR_END));
                   1521: }
                   1522: 
                   1523: /************************lvector *******************************/
                   1524: long *lvector(long nl,long nh)
                   1525: {
                   1526:   long *v;
                   1527:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1528:   if (!v) nrerror("allocation failure in ivector");
                   1529:   return v-nl+NR_END;
                   1530: }
                   1531: 
                   1532: /******************free lvector **************************/
                   1533: void free_lvector(long *v, long nl, long nh)
                   1534: {
                   1535:   free((FREE_ARG)(v+nl-NR_END));
                   1536: }
                   1537: 
                   1538: /******************* imatrix *******************************/
                   1539: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1540:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1541: { 
                   1542:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1543:   int **m; 
                   1544:   
                   1545:   /* allocate pointers to rows */ 
                   1546:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1547:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1548:   m += NR_END; 
                   1549:   m -= nrl; 
                   1550:   
                   1551:   
                   1552:   /* allocate rows and set pointers to them */ 
                   1553:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1554:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1555:   m[nrl] += NR_END; 
                   1556:   m[nrl] -= ncl; 
                   1557:   
                   1558:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1559:   
                   1560:   /* return pointer to array of pointers to rows */ 
                   1561:   return m; 
                   1562: } 
                   1563: 
                   1564: /****************** free_imatrix *************************/
                   1565: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1566:       int **m;
                   1567:       long nch,ncl,nrh,nrl; 
                   1568:      /* free an int matrix allocated by imatrix() */ 
                   1569: { 
                   1570:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1571:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1572: } 
                   1573: 
                   1574: /******************* matrix *******************************/
                   1575: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1576: {
                   1577:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1578:   double **m;
                   1579: 
                   1580:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1581:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1582:   m += NR_END;
                   1583:   m -= nrl;
                   1584: 
                   1585:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1586:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1587:   m[nrl] += NR_END;
                   1588:   m[nrl] -= ncl;
                   1589: 
                   1590:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1591:   return m;
1.145     brouard  1592:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1593: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1594: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1595:    */
                   1596: }
                   1597: 
                   1598: /*************************free matrix ************************/
                   1599: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1600: {
                   1601:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1602:   free((FREE_ARG)(m+nrl-NR_END));
                   1603: }
                   1604: 
                   1605: /******************* ma3x *******************************/
                   1606: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1607: {
                   1608:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1609:   double ***m;
                   1610: 
                   1611:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1612:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1613:   m += NR_END;
                   1614:   m -= nrl;
                   1615: 
                   1616:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1617:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1618:   m[nrl] += NR_END;
                   1619:   m[nrl] -= ncl;
                   1620: 
                   1621:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1622: 
                   1623:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1624:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1625:   m[nrl][ncl] += NR_END;
                   1626:   m[nrl][ncl] -= nll;
                   1627:   for (j=ncl+1; j<=nch; j++) 
                   1628:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1629:   
                   1630:   for (i=nrl+1; i<=nrh; i++) {
                   1631:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1632:     for (j=ncl+1; j<=nch; j++) 
                   1633:       m[i][j]=m[i][j-1]+nlay;
                   1634:   }
                   1635:   return m; 
                   1636:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1637:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1638:   */
                   1639: }
                   1640: 
                   1641: /*************************free ma3x ************************/
                   1642: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1643: {
                   1644:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1645:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1646:   free((FREE_ARG)(m+nrl-NR_END));
                   1647: }
                   1648: 
                   1649: /*************** function subdirf ***********/
                   1650: char *subdirf(char fileres[])
                   1651: {
                   1652:   /* Caution optionfilefiname is hidden */
                   1653:   strcpy(tmpout,optionfilefiname);
                   1654:   strcat(tmpout,"/"); /* Add to the right */
                   1655:   strcat(tmpout,fileres);
                   1656:   return tmpout;
                   1657: }
                   1658: 
                   1659: /*************** function subdirf2 ***********/
                   1660: char *subdirf2(char fileres[], char *preop)
                   1661: {
                   1662:   
                   1663:   /* Caution optionfilefiname is hidden */
                   1664:   strcpy(tmpout,optionfilefiname);
                   1665:   strcat(tmpout,"/");
                   1666:   strcat(tmpout,preop);
                   1667:   strcat(tmpout,fileres);
                   1668:   return tmpout;
                   1669: }
                   1670: 
                   1671: /*************** function subdirf3 ***********/
                   1672: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1673: {
                   1674:   
                   1675:   /* Caution optionfilefiname is hidden */
                   1676:   strcpy(tmpout,optionfilefiname);
                   1677:   strcat(tmpout,"/");
                   1678:   strcat(tmpout,preop);
                   1679:   strcat(tmpout,preop2);
                   1680:   strcat(tmpout,fileres);
                   1681:   return tmpout;
                   1682: }
1.213     brouard  1683:  
                   1684: /*************** function subdirfext ***********/
                   1685: char *subdirfext(char fileres[], char *preop, char *postop)
                   1686: {
                   1687:   
                   1688:   strcpy(tmpout,preop);
                   1689:   strcat(tmpout,fileres);
                   1690:   strcat(tmpout,postop);
                   1691:   return tmpout;
                   1692: }
1.126     brouard  1693: 
1.213     brouard  1694: /*************** function subdirfext3 ***********/
                   1695: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1696: {
                   1697:   
                   1698:   /* Caution optionfilefiname is hidden */
                   1699:   strcpy(tmpout,optionfilefiname);
                   1700:   strcat(tmpout,"/");
                   1701:   strcat(tmpout,preop);
                   1702:   strcat(tmpout,fileres);
                   1703:   strcat(tmpout,postop);
                   1704:   return tmpout;
                   1705: }
                   1706:  
1.162     brouard  1707: char *asc_diff_time(long time_sec, char ascdiff[])
                   1708: {
                   1709:   long sec_left, days, hours, minutes;
                   1710:   days = (time_sec) / (60*60*24);
                   1711:   sec_left = (time_sec) % (60*60*24);
                   1712:   hours = (sec_left) / (60*60) ;
                   1713:   sec_left = (sec_left) %(60*60);
                   1714:   minutes = (sec_left) /60;
                   1715:   sec_left = (sec_left) % (60);
                   1716:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1717:   return ascdiff;
                   1718: }
                   1719: 
1.126     brouard  1720: /***************** f1dim *************************/
                   1721: extern int ncom; 
                   1722: extern double *pcom,*xicom;
                   1723: extern double (*nrfunc)(double []); 
                   1724:  
                   1725: double f1dim(double x) 
                   1726: { 
                   1727:   int j; 
                   1728:   double f;
                   1729:   double *xt; 
                   1730:  
                   1731:   xt=vector(1,ncom); 
                   1732:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1733:   f=(*nrfunc)(xt); 
                   1734:   free_vector(xt,1,ncom); 
                   1735:   return f; 
                   1736: } 
                   1737: 
                   1738: /*****************brent *************************/
                   1739: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1740: {
                   1741:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1742:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1743:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1744:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1745:    * returned function value. 
                   1746:   */
1.126     brouard  1747:   int iter; 
                   1748:   double a,b,d,etemp;
1.159     brouard  1749:   double fu=0,fv,fw,fx;
1.164     brouard  1750:   double ftemp=0.;
1.126     brouard  1751:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1752:   double e=0.0; 
                   1753:  
                   1754:   a=(ax < cx ? ax : cx); 
                   1755:   b=(ax > cx ? ax : cx); 
                   1756:   x=w=v=bx; 
                   1757:   fw=fv=fx=(*f)(x); 
                   1758:   for (iter=1;iter<=ITMAX;iter++) { 
                   1759:     xm=0.5*(a+b); 
                   1760:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1761:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1762:     printf(".");fflush(stdout);
                   1763:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1764: #ifdef DEBUGBRENT
1.126     brouard  1765:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1766:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1767:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1768: #endif
                   1769:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1770:       *xmin=x; 
                   1771:       return fx; 
                   1772:     } 
                   1773:     ftemp=fu;
                   1774:     if (fabs(e) > tol1) { 
                   1775:       r=(x-w)*(fx-fv); 
                   1776:       q=(x-v)*(fx-fw); 
                   1777:       p=(x-v)*q-(x-w)*r; 
                   1778:       q=2.0*(q-r); 
                   1779:       if (q > 0.0) p = -p; 
                   1780:       q=fabs(q); 
                   1781:       etemp=e; 
                   1782:       e=d; 
                   1783:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1784:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1785:       else { 
1.224     brouard  1786:                                d=p/q; 
                   1787:                                u=x+d; 
                   1788:                                if (u-a < tol2 || b-u < tol2) 
                   1789:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1790:       } 
                   1791:     } else { 
                   1792:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1793:     } 
                   1794:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1795:     fu=(*f)(u); 
                   1796:     if (fu <= fx) { 
                   1797:       if (u >= x) a=x; else b=x; 
                   1798:       SHFT(v,w,x,u) 
1.183     brouard  1799:       SHFT(fv,fw,fx,fu) 
                   1800:     } else { 
                   1801:       if (u < x) a=u; else b=u; 
                   1802:       if (fu <= fw || w == x) { 
1.224     brouard  1803:                                v=w; 
                   1804:                                w=u; 
                   1805:                                fv=fw; 
                   1806:                                fw=fu; 
1.183     brouard  1807:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1808:                                v=u; 
                   1809:                                fv=fu; 
1.183     brouard  1810:       } 
                   1811:     } 
1.126     brouard  1812:   } 
                   1813:   nrerror("Too many iterations in brent"); 
                   1814:   *xmin=x; 
                   1815:   return fx; 
                   1816: } 
                   1817: 
                   1818: /****************** mnbrak ***********************/
                   1819: 
                   1820: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1821:            double (*func)(double)) 
1.183     brouard  1822: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1823: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1824: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1825: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1826:    */
1.126     brouard  1827:   double ulim,u,r,q, dum;
                   1828:   double fu; 
1.187     brouard  1829: 
                   1830:   double scale=10.;
                   1831:   int iterscale=0;
                   1832: 
                   1833:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1834:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1835: 
                   1836: 
                   1837:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1838:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1839:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1840:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1841:   /* } */
                   1842: 
1.126     brouard  1843:   if (*fb > *fa) { 
                   1844:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1845:     SHFT(dum,*fb,*fa,dum) 
                   1846:   } 
1.126     brouard  1847:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1848:   *fc=(*func)(*cx); 
1.183     brouard  1849: #ifdef DEBUG
1.224     brouard  1850:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1851:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1852: #endif
1.224     brouard  1853:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1854:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1855:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1856:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1857:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1858:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1859:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1860:       fu=(*func)(u); 
1.163     brouard  1861: #ifdef DEBUG
                   1862:       /* f(x)=A(x-u)**2+f(u) */
                   1863:       double A, fparabu; 
                   1864:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1865:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1866:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1867:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1868:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1869:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1870:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1871:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1872: #endif 
1.184     brouard  1873: #ifdef MNBRAKORIGINAL
1.183     brouard  1874: #else
1.191     brouard  1875: /*       if (fu > *fc) { */
                   1876: /* #ifdef DEBUG */
                   1877: /*       printf("mnbrak4  fu > fc \n"); */
                   1878: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1879: /* #endif */
                   1880: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1881: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1882: /*     dum=u; /\* Shifting c and u *\/ */
                   1883: /*     u = *cx; */
                   1884: /*     *cx = dum; */
                   1885: /*     dum = fu; */
                   1886: /*     fu = *fc; */
                   1887: /*     *fc =dum; */
                   1888: /*       } else { /\* end *\/ */
                   1889: /* #ifdef DEBUG */
                   1890: /*       printf("mnbrak3  fu < fc \n"); */
                   1891: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1892: /* #endif */
                   1893: /*     dum=u; /\* Shifting c and u *\/ */
                   1894: /*     u = *cx; */
                   1895: /*     *cx = dum; */
                   1896: /*     dum = fu; */
                   1897: /*     fu = *fc; */
                   1898: /*     *fc =dum; */
                   1899: /*       } */
1.224     brouard  1900: #ifdef DEBUGMNBRAK
                   1901:                 double A, fparabu; 
                   1902:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1903:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1904:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1905:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1906: #endif
1.191     brouard  1907:       dum=u; /* Shifting c and u */
                   1908:       u = *cx;
                   1909:       *cx = dum;
                   1910:       dum = fu;
                   1911:       fu = *fc;
                   1912:       *fc =dum;
1.183     brouard  1913: #endif
1.162     brouard  1914:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1915: #ifdef DEBUG
1.224     brouard  1916:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1917:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1918: #endif
1.126     brouard  1919:       fu=(*func)(u); 
                   1920:       if (fu < *fc) { 
1.183     brouard  1921: #ifdef DEBUG
1.224     brouard  1922:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1923:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1924: #endif
                   1925:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1926:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1927: #ifdef DEBUG
                   1928:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1929: #endif
                   1930:       } 
1.162     brouard  1931:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1932: #ifdef DEBUG
1.224     brouard  1933:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1934:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1935: #endif
1.126     brouard  1936:       u=ulim; 
                   1937:       fu=(*func)(u); 
1.183     brouard  1938:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1939: #ifdef DEBUG
1.224     brouard  1940:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1941:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1942: #endif
1.126     brouard  1943:       u=(*cx)+GOLD*(*cx-*bx); 
                   1944:       fu=(*func)(u); 
1.224     brouard  1945: #ifdef DEBUG
                   1946:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1947:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1948: #endif
1.183     brouard  1949:     } /* end tests */
1.126     brouard  1950:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  1951:     SHFT(*fa,*fb,*fc,fu) 
                   1952: #ifdef DEBUG
1.224     brouard  1953:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   1954:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  1955: #endif
                   1956:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  1957: } 
                   1958: 
                   1959: /*************** linmin ************************/
1.162     brouard  1960: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   1961: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   1962: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   1963: the value of func at the returned location p . This is actually all accomplished by calling the
                   1964: routines mnbrak and brent .*/
1.126     brouard  1965: int ncom; 
                   1966: double *pcom,*xicom;
                   1967: double (*nrfunc)(double []); 
                   1968:  
1.224     brouard  1969: #ifdef LINMINORIGINAL
1.126     brouard  1970: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  1971: #else
                   1972: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   1973: #endif
1.126     brouard  1974: { 
                   1975:   double brent(double ax, double bx, double cx, 
                   1976:               double (*f)(double), double tol, double *xmin); 
                   1977:   double f1dim(double x); 
                   1978:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   1979:              double *fc, double (*func)(double)); 
                   1980:   int j; 
                   1981:   double xx,xmin,bx,ax; 
                   1982:   double fx,fb,fa;
1.187     brouard  1983: 
1.203     brouard  1984: #ifdef LINMINORIGINAL
                   1985: #else
                   1986:   double scale=10., axs, xxs; /* Scale added for infinity */
                   1987: #endif
                   1988:   
1.126     brouard  1989:   ncom=n; 
                   1990:   pcom=vector(1,n); 
                   1991:   xicom=vector(1,n); 
                   1992:   nrfunc=func; 
                   1993:   for (j=1;j<=n;j++) { 
                   1994:     pcom[j]=p[j]; 
1.202     brouard  1995:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  1996:   } 
1.187     brouard  1997: 
1.203     brouard  1998: #ifdef LINMINORIGINAL
                   1999:   xx=1.;
                   2000: #else
                   2001:   axs=0.0;
                   2002:   xxs=1.;
                   2003:   do{
                   2004:     xx= xxs;
                   2005: #endif
1.187     brouard  2006:     ax=0.;
                   2007:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2008:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2009:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2010:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2011:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2012:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2013:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2014: #ifdef LINMINORIGINAL
                   2015: #else
                   2016:     if (fx != fx){
1.224     brouard  2017:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2018:                        printf("|");
                   2019:                        fprintf(ficlog,"|");
1.203     brouard  2020: #ifdef DEBUGLINMIN
1.224     brouard  2021:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2022: #endif
                   2023:     }
1.224     brouard  2024:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2025: #endif
                   2026:   
1.191     brouard  2027: #ifdef DEBUGLINMIN
                   2028:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2029:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2030: #endif
1.224     brouard  2031: #ifdef LINMINORIGINAL
                   2032: #else
                   2033:        if(fb == fx){ /* Flat function in the direction */
                   2034:                xmin=xx;
                   2035:     *flat=1;
                   2036:        }else{
                   2037:     *flat=0;
                   2038: #endif
                   2039:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2040:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2041:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2042:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2043:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2044:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2045: #ifdef DEBUG
1.224     brouard  2046:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2047:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2048: #endif
                   2049: #ifdef LINMINORIGINAL
                   2050: #else
                   2051:                        }
1.126     brouard  2052: #endif
1.191     brouard  2053: #ifdef DEBUGLINMIN
                   2054:   printf("linmin end ");
1.202     brouard  2055:   fprintf(ficlog,"linmin end ");
1.191     brouard  2056: #endif
1.126     brouard  2057:   for (j=1;j<=n;j++) { 
1.203     brouard  2058: #ifdef LINMINORIGINAL
                   2059:     xi[j] *= xmin; 
                   2060: #else
                   2061: #ifdef DEBUGLINMIN
                   2062:     if(xxs <1.0)
                   2063:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2064: #endif
                   2065:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2066: #ifdef DEBUGLINMIN
                   2067:     if(xxs <1.0)
                   2068:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2069: #endif
                   2070: #endif
1.187     brouard  2071:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2072:   } 
1.191     brouard  2073: #ifdef DEBUGLINMIN
1.203     brouard  2074:   printf("\n");
1.191     brouard  2075:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2076:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2077:   for (j=1;j<=n;j++) { 
1.202     brouard  2078:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2079:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2080:     if(j % ncovmodel == 0){
1.191     brouard  2081:       printf("\n");
1.202     brouard  2082:       fprintf(ficlog,"\n");
                   2083:     }
1.191     brouard  2084:   }
1.203     brouard  2085: #else
1.191     brouard  2086: #endif
1.126     brouard  2087:   free_vector(xicom,1,n); 
                   2088:   free_vector(pcom,1,n); 
                   2089: } 
                   2090: 
                   2091: 
                   2092: /*************** powell ************************/
1.162     brouard  2093: /*
                   2094: Minimization of a function func of n variables. Input consists of an initial starting point
                   2095: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2096: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2097: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2098: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2099: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2100:  */
1.224     brouard  2101: #ifdef LINMINORIGINAL
                   2102: #else
                   2103:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2104:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2105: #endif
1.126     brouard  2106: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2107:            double (*func)(double [])) 
                   2108: { 
1.224     brouard  2109: #ifdef LINMINORIGINAL
                   2110:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2111:              double (*func)(double [])); 
1.224     brouard  2112: #else 
1.241     brouard  2113:  void linmin(double p[], double xi[], int n, double *fret,
                   2114:             double (*func)(double []),int *flat); 
1.224     brouard  2115: #endif
1.239     brouard  2116:  int i,ibig,j,jk,k; 
1.126     brouard  2117:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2118:   double directest;
1.126     brouard  2119:   double fp,fptt;
                   2120:   double *xits;
                   2121:   int niterf, itmp;
1.224     brouard  2122: #ifdef LINMINORIGINAL
                   2123: #else
                   2124: 
                   2125:   flatdir=ivector(1,n); 
                   2126:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2127: #endif
1.126     brouard  2128: 
                   2129:   pt=vector(1,n); 
                   2130:   ptt=vector(1,n); 
                   2131:   xit=vector(1,n); 
                   2132:   xits=vector(1,n); 
                   2133:   *fret=(*func)(p); 
                   2134:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2135:   rcurr_time = time(NULL);  
1.126     brouard  2136:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2137:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2138:     ibig=0; 
                   2139:     del=0.0; 
1.157     brouard  2140:     rlast_time=rcurr_time;
                   2141:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2142:     rcurr_time = time(NULL);  
                   2143:     curr_time = *localtime(&rcurr_time);
                   2144:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2145:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2146: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2147:     for (i=1;i<=n;i++) {
1.126     brouard  2148:       fprintf(ficrespow," %.12lf", p[i]);
                   2149:     }
1.239     brouard  2150:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2151:     printf("\n#model=  1      +     age ");
                   2152:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2153:     if(nagesqr==1){
1.241     brouard  2154:        printf("  + age*age  ");
                   2155:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2156:     }
                   2157:     for(j=1;j <=ncovmodel-2;j++){
                   2158:       if(Typevar[j]==0) {
                   2159:        printf("  +      V%d  ",Tvar[j]);
                   2160:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2161:       }else if(Typevar[j]==1) {
                   2162:        printf("  +    V%d*age ",Tvar[j]);
                   2163:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2164:       }else if(Typevar[j]==2) {
                   2165:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2166:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2167:       }
                   2168:     }
1.126     brouard  2169:     printf("\n");
1.239     brouard  2170: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2171: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2172:     fprintf(ficlog,"\n");
1.239     brouard  2173:     for(i=1,jk=1; i <=nlstate; i++){
                   2174:       for(k=1; k <=(nlstate+ndeath); k++){
                   2175:        if (k != i) {
                   2176:          printf("%d%d ",i,k);
                   2177:          fprintf(ficlog,"%d%d ",i,k);
                   2178:          for(j=1; j <=ncovmodel; j++){
                   2179:            printf("%12.7f ",p[jk]);
                   2180:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2181:            jk++; 
                   2182:          }
                   2183:          printf("\n");
                   2184:          fprintf(ficlog,"\n");
                   2185:        }
                   2186:       }
                   2187:     }
1.241     brouard  2188:     if(*iter <=3 && *iter >1){
1.157     brouard  2189:       tml = *localtime(&rcurr_time);
                   2190:       strcpy(strcurr,asctime(&tml));
                   2191:       rforecast_time=rcurr_time; 
1.126     brouard  2192:       itmp = strlen(strcurr);
                   2193:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2194:        strcurr[itmp-1]='\0';
1.162     brouard  2195:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2196:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2197:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2198:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2199:        forecast_time = *localtime(&rforecast_time);
                   2200:        strcpy(strfor,asctime(&forecast_time));
                   2201:        itmp = strlen(strfor);
                   2202:        if(strfor[itmp-1]=='\n')
                   2203:          strfor[itmp-1]='\0';
                   2204:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2205:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2206:       }
                   2207:     }
1.187     brouard  2208:     for (i=1;i<=n;i++) { /* For each direction i */
                   2209:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2210:       fptt=(*fret); 
                   2211: #ifdef DEBUG
1.203     brouard  2212:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2213:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2214: #endif
1.203     brouard  2215:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2216:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2217: #ifdef LINMINORIGINAL
1.188     brouard  2218:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2219: #else
                   2220:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2221:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2222: #endif
                   2223:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2224:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2225:                                /* because that direction will be replaced unless the gain del is small */
                   2226:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2227:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2228:                                /* with the new direction. */
                   2229:                                del=fabs(fptt-(*fret)); 
                   2230:                                ibig=i; 
1.126     brouard  2231:       } 
                   2232: #ifdef DEBUG
                   2233:       printf("%d %.12e",i,(*fret));
                   2234:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2235:       for (j=1;j<=n;j++) {
1.224     brouard  2236:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2237:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2238:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2239:       }
                   2240:       for(j=1;j<=n;j++) {
1.225     brouard  2241:                                printf(" p(%d)=%.12e",j,p[j]);
                   2242:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2243:       }
                   2244:       printf("\n");
                   2245:       fprintf(ficlog,"\n");
                   2246: #endif
1.187     brouard  2247:     } /* end loop on each direction i */
                   2248:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2249:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2250:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2251:       for(j=1;j<=n;j++) {
1.225     brouard  2252:                                if(flatdir[j] >0){
                   2253:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2254:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2255:                                }
                   2256:                                /* printf("\n"); */
                   2257:                                /* fprintf(ficlog,"\n"); */
                   2258:                        }
1.243     brouard  2259:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2260:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2261:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2262:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2263:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2264:       /* decreased of more than 3.84  */
                   2265:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2266:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2267:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2268:                        
1.188     brouard  2269:       /* Starting the program with initial values given by a former maximization will simply change */
                   2270:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2271:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2272:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2273: #ifdef DEBUG
                   2274:       int k[2],l;
                   2275:       k[0]=1;
                   2276:       k[1]=-1;
                   2277:       printf("Max: %.12e",(*func)(p));
                   2278:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2279:       for (j=1;j<=n;j++) {
                   2280:        printf(" %.12e",p[j]);
                   2281:        fprintf(ficlog," %.12e",p[j]);
                   2282:       }
                   2283:       printf("\n");
                   2284:       fprintf(ficlog,"\n");
                   2285:       for(l=0;l<=1;l++) {
                   2286:        for (j=1;j<=n;j++) {
                   2287:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2288:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2289:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2290:        }
                   2291:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2292:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2293:       }
                   2294: #endif
                   2295: 
1.224     brouard  2296: #ifdef LINMINORIGINAL
                   2297: #else
                   2298:       free_ivector(flatdir,1,n); 
                   2299: #endif
1.126     brouard  2300:       free_vector(xit,1,n); 
                   2301:       free_vector(xits,1,n); 
                   2302:       free_vector(ptt,1,n); 
                   2303:       free_vector(pt,1,n); 
                   2304:       return; 
1.192     brouard  2305:     } /* enough precision */ 
1.240     brouard  2306:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2307:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2308:       ptt[j]=2.0*p[j]-pt[j]; 
                   2309:       xit[j]=p[j]-pt[j]; 
                   2310:       pt[j]=p[j]; 
                   2311:     } 
1.181     brouard  2312:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2313: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2314:                if (*iter <=4) {
1.225     brouard  2315: #else
                   2316: #endif
1.224     brouard  2317: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2318: #else
1.161     brouard  2319:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2320: #endif
1.162     brouard  2321:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2322:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2323:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2324:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2325:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2326:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2327:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2328:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2329:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2330:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2331:       /* mu² and del² are equal when f3=f1 */
                   2332:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2333:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2334:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2335:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2336: #ifdef NRCORIGINAL
                   2337:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2338: #else
                   2339:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2340:       t= t- del*SQR(fp-fptt);
1.183     brouard  2341: #endif
1.202     brouard  2342:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2343: #ifdef DEBUG
1.181     brouard  2344:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2345:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2346:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2347:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2348:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2349:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2350:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2351:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2352: #endif
1.183     brouard  2353: #ifdef POWELLORIGINAL
                   2354:       if (t < 0.0) { /* Then we use it for new direction */
                   2355: #else
1.182     brouard  2356:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2357:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2358:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2359:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2360:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2361:       } 
1.181     brouard  2362:       if (directest < 0.0) { /* Then we use it for new direction */
                   2363: #endif
1.191     brouard  2364: #ifdef DEBUGLINMIN
1.234     brouard  2365:        printf("Before linmin in direction P%d-P0\n",n);
                   2366:        for (j=1;j<=n;j++) {
                   2367:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2368:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2369:          if(j % ncovmodel == 0){
                   2370:            printf("\n");
                   2371:            fprintf(ficlog,"\n");
                   2372:          }
                   2373:        }
1.224     brouard  2374: #endif
                   2375: #ifdef LINMINORIGINAL
1.234     brouard  2376:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2377: #else
1.234     brouard  2378:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2379:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2380: #endif
1.234     brouard  2381:        
1.191     brouard  2382: #ifdef DEBUGLINMIN
1.234     brouard  2383:        for (j=1;j<=n;j++) { 
                   2384:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2385:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2386:          if(j % ncovmodel == 0){
                   2387:            printf("\n");
                   2388:            fprintf(ficlog,"\n");
                   2389:          }
                   2390:        }
1.224     brouard  2391: #endif
1.234     brouard  2392:        for (j=1;j<=n;j++) { 
                   2393:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2394:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2395:        }
1.224     brouard  2396: #ifdef LINMINORIGINAL
                   2397: #else
1.234     brouard  2398:        for (j=1, flatd=0;j<=n;j++) {
                   2399:          if(flatdir[j]>0)
                   2400:            flatd++;
                   2401:        }
                   2402:        if(flatd >0){
1.255   ! brouard  2403:          printf("%d flat directions: ",flatd);
        !          2404:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2405:          for (j=1;j<=n;j++) { 
                   2406:            if(flatdir[j]>0){
                   2407:              printf("%d ",j);
                   2408:              fprintf(ficlog,"%d ",j);
                   2409:            }
                   2410:          }
                   2411:          printf("\n");
                   2412:          fprintf(ficlog,"\n");
                   2413:        }
1.191     brouard  2414: #endif
1.234     brouard  2415:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2416:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2417:        
1.126     brouard  2418: #ifdef DEBUG
1.234     brouard  2419:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2420:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2421:        for(j=1;j<=n;j++){
                   2422:          printf(" %lf",xit[j]);
                   2423:          fprintf(ficlog," %lf",xit[j]);
                   2424:        }
                   2425:        printf("\n");
                   2426:        fprintf(ficlog,"\n");
1.126     brouard  2427: #endif
1.192     brouard  2428:       } /* end of t or directest negative */
1.224     brouard  2429: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2430: #else
1.234     brouard  2431:       } /* end if (fptt < fp)  */
1.192     brouard  2432: #endif
1.225     brouard  2433: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2434:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2435: #else
1.224     brouard  2436: #endif
1.234     brouard  2437:                } /* loop iteration */ 
1.126     brouard  2438: } 
1.234     brouard  2439:   
1.126     brouard  2440: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2441:   
1.235     brouard  2442:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2443:   {
1.235     brouard  2444:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2445:        (and selected quantitative values in nres)
                   2446:        by left multiplying the unit
1.234     brouard  2447:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2448:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2449:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2450:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2451:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2452:   /* Initial matrix pimij */
                   2453:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2454:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2455:   /*  0,                   0                  , 1} */
                   2456:   /*
                   2457:    * and after some iteration: */
                   2458:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2459:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2460:   /*  0,                   0                  , 1} */
                   2461:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2462:   /* {0.51571254859325999, 0.4842874514067399, */
                   2463:   /*  0.51326036147820708, 0.48673963852179264} */
                   2464:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2465:     
1.126     brouard  2466:   int i, ii,j,k;
1.209     brouard  2467:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2468:   /* double **matprod2(); */ /* test */
1.218     brouard  2469:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2470:   double **newm;
1.209     brouard  2471:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2472:   int ncvloop=0;
1.169     brouard  2473:   
1.209     brouard  2474:   min=vector(1,nlstate);
                   2475:   max=vector(1,nlstate);
                   2476:   meandiff=vector(1,nlstate);
                   2477: 
1.218     brouard  2478:        /* Starting with matrix unity */
1.126     brouard  2479:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2480:     for (j=1;j<=nlstate+ndeath;j++){
                   2481:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2482:     }
1.169     brouard  2483:   
                   2484:   cov[1]=1.;
                   2485:   
                   2486:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2487:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2488:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2489:     ncvloop++;
1.126     brouard  2490:     newm=savm;
                   2491:     /* Covariates have to be included here again */
1.138     brouard  2492:     cov[2]=agefin;
1.187     brouard  2493:     if(nagesqr==1)
                   2494:       cov[3]= agefin*agefin;;
1.234     brouard  2495:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2496:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2497:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2498:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2499:     }
                   2500:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2501:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2502:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2503:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2504:     }
1.237     brouard  2505:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2506:       if(Dummy[Tvar[Tage[k]]]){
                   2507:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2508:       } else{
1.235     brouard  2509:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2510:       }
1.235     brouard  2511:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2512:     }
1.237     brouard  2513:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2514:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2515:       if(Dummy[Tvard[k][1]==0]){
                   2516:        if(Dummy[Tvard[k][2]==0]){
                   2517:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2518:        }else{
                   2519:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2520:        }
                   2521:       }else{
                   2522:        if(Dummy[Tvard[k][2]==0]){
                   2523:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2524:        }else{
                   2525:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2526:        }
                   2527:       }
1.234     brouard  2528:     }
1.138     brouard  2529:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2530:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2531:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2532:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2533:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2534:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2535:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2536:     
1.126     brouard  2537:     savm=oldm;
                   2538:     oldm=newm;
1.209     brouard  2539: 
                   2540:     for(j=1; j<=nlstate; j++){
                   2541:       max[j]=0.;
                   2542:       min[j]=1.;
                   2543:     }
                   2544:     for(i=1;i<=nlstate;i++){
                   2545:       sumnew=0;
                   2546:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2547:       for(j=1; j<=nlstate; j++){ 
                   2548:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2549:        max[j]=FMAX(max[j],prlim[i][j]);
                   2550:        min[j]=FMIN(min[j],prlim[i][j]);
                   2551:       }
                   2552:     }
                   2553: 
1.126     brouard  2554:     maxmax=0.;
1.209     brouard  2555:     for(j=1; j<=nlstate; j++){
                   2556:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2557:       maxmax=FMAX(maxmax,meandiff[j]);
                   2558:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2559:     } /* j loop */
1.203     brouard  2560:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2561:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2562:     if(maxmax < ftolpl){
1.209     brouard  2563:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2564:       free_vector(min,1,nlstate);
                   2565:       free_vector(max,1,nlstate);
                   2566:       free_vector(meandiff,1,nlstate);
1.126     brouard  2567:       return prlim;
                   2568:     }
1.169     brouard  2569:   } /* age loop */
1.208     brouard  2570:     /* After some age loop it doesn't converge */
1.209     brouard  2571:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2572: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2573:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2574:   free_vector(min,1,nlstate);
                   2575:   free_vector(max,1,nlstate);
                   2576:   free_vector(meandiff,1,nlstate);
1.208     brouard  2577:   
1.169     brouard  2578:   return prlim; /* should not reach here */
1.126     brouard  2579: }
                   2580: 
1.217     brouard  2581: 
                   2582:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2583: 
1.218     brouard  2584:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2585:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2586:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2587: {
1.218     brouard  2588:   /* Computes the prevalence limit in each live state at age x and covariate ij by left multiplying the unit
1.217     brouard  2589:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2590:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2591:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2592:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2593:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2594:   /* Initial matrix pimij */
                   2595:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2596:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2597:   /*  0,                   0                  , 1} */
                   2598:   /*
                   2599:    * and after some iteration: */
                   2600:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2601:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2602:   /*  0,                   0                  , 1} */
                   2603:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2604:   /* {0.51571254859325999, 0.4842874514067399, */
                   2605:   /*  0.51326036147820708, 0.48673963852179264} */
                   2606:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2607: 
                   2608:   int i, ii,j,k;
1.247     brouard  2609:   int first=0;
1.217     brouard  2610:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2611:   /* double **matprod2(); */ /* test */
                   2612:   double **out, cov[NCOVMAX+1], **bmij();
                   2613:   double **newm;
1.218     brouard  2614:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2615:   double        **oldm, **savm;  /* for use */
                   2616: 
1.217     brouard  2617:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2618:   int ncvloop=0;
                   2619:   
                   2620:   min=vector(1,nlstate);
                   2621:   max=vector(1,nlstate);
                   2622:   meandiff=vector(1,nlstate);
                   2623: 
1.218     brouard  2624:        dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2625:        oldm=oldms; savm=savms;
                   2626: 
                   2627:        /* Starting with matrix unity */
                   2628:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   2629:                for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2630:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2631:     }
                   2632:   
                   2633:   cov[1]=1.;
                   2634:   
                   2635:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2636:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2637:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2638:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2639:     ncvloop++;
1.218     brouard  2640:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2641:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2642:     /* Covariates have to be included here again */
                   2643:     cov[2]=agefin;
                   2644:     if(nagesqr==1)
                   2645:       cov[3]= agefin*agefin;;
1.242     brouard  2646:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2647:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2648:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   2649:       /* printf("bprevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   2650:     }
                   2651:     /* for (k=1; k<=cptcovn;k++) { */
                   2652:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2653:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2654:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2655:     /* } */
                   2656:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2657:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2658:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2659:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2660:     }
                   2661:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2662:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2663:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2664:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2665:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2666:       if(Dummy[Tvar[Tage[k]]]){
                   2667:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2668:       } else{
                   2669:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2670:       }
                   2671:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2672:     }
                   2673:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2674:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2675:       if(Dummy[Tvard[k][1]==0]){
                   2676:        if(Dummy[Tvard[k][2]==0]){
                   2677:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2678:        }else{
                   2679:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2680:        }
                   2681:       }else{
                   2682:        if(Dummy[Tvard[k][2]==0]){
                   2683:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2684:        }else{
                   2685:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2686:        }
                   2687:       }
1.217     brouard  2688:     }
                   2689:     
                   2690:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2691:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2692:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2693:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2694:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2695:                /* ij should be linked to the correct index of cov */
                   2696:                /* age and covariate values ij are in 'cov', but we need to pass
                   2697:                 * ij for the observed prevalence at age and status and covariate
                   2698:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2699:                 */
                   2700:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2701:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2702:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.217     brouard  2703:     savm=oldm;
                   2704:     oldm=newm;
                   2705:     for(j=1; j<=nlstate; j++){
                   2706:       max[j]=0.;
                   2707:       min[j]=1.;
                   2708:     }
                   2709:     for(j=1; j<=nlstate; j++){ 
                   2710:       for(i=1;i<=nlstate;i++){
1.234     brouard  2711:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2712:        bprlim[i][j]= newm[i][j];
                   2713:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2714:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2715:       }
                   2716:     }
1.218     brouard  2717:                
1.217     brouard  2718:     maxmax=0.;
                   2719:     for(i=1; i<=nlstate; i++){
                   2720:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2721:       maxmax=FMAX(maxmax,meandiff[i]);
                   2722:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
                   2723:     } /* j loop */
                   2724:     *ncvyear= -( (int)age- (int)agefin);
1.218     brouard  2725:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear);*/
1.217     brouard  2726:     if(maxmax < ftolpl){
1.220     brouard  2727:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2728:       free_vector(min,1,nlstate);
                   2729:       free_vector(max,1,nlstate);
                   2730:       free_vector(meandiff,1,nlstate);
                   2731:       return bprlim;
                   2732:     }
                   2733:   } /* age loop */
                   2734:     /* After some age loop it doesn't converge */
1.247     brouard  2735:   if(first){
                   2736:     first=1;
                   2737:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2738: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2739:   }
                   2740:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2741: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2742:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2743:   free_vector(min,1,nlstate);
                   2744:   free_vector(max,1,nlstate);
                   2745:   free_vector(meandiff,1,nlstate);
                   2746:   
                   2747:   return bprlim; /* should not reach here */
                   2748: }
                   2749: 
1.126     brouard  2750: /*************** transition probabilities ***************/ 
                   2751: 
                   2752: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2753: {
1.138     brouard  2754:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2755:      computes the probability to be observed in state j being in state i by appying the
                   2756:      model to the ncovmodel covariates (including constant and age).
                   2757:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2758:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2759:      ncth covariate in the global vector x is given by the formula:
                   2760:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2761:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2762:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2763:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2764:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2765:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2766:   */
                   2767:   double s1, lnpijopii;
1.126     brouard  2768:   /*double t34;*/
1.164     brouard  2769:   int i,j, nc, ii, jj;
1.126     brouard  2770: 
1.223     brouard  2771:   for(i=1; i<= nlstate; i++){
                   2772:     for(j=1; j<i;j++){
                   2773:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2774:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2775:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2776:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2777:       }
                   2778:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2779:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2780:     }
                   2781:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2782:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2783:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2784:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2785:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2786:       }
                   2787:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2788:     }
                   2789:   }
1.218     brouard  2790:   
1.223     brouard  2791:   for(i=1; i<= nlstate; i++){
                   2792:     s1=0;
                   2793:     for(j=1; j<i; j++){
                   2794:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2795:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2796:     }
                   2797:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2798:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2799:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2800:     }
                   2801:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2802:     ps[i][i]=1./(s1+1.);
                   2803:     /* Computing other pijs */
                   2804:     for(j=1; j<i; j++)
                   2805:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2806:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2807:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2808:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2809:   } /* end i */
1.218     brouard  2810:   
1.223     brouard  2811:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2812:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2813:       ps[ii][jj]=0;
                   2814:       ps[ii][ii]=1;
                   2815:     }
                   2816:   }
1.218     brouard  2817:   
                   2818:   
1.223     brouard  2819:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2820:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2821:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2822:   /*   } */
                   2823:   /*   printf("\n "); */
                   2824:   /* } */
                   2825:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2826:   /*
                   2827:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2828:                goto end;*/
1.223     brouard  2829:   return ps;
1.126     brouard  2830: }
                   2831: 
1.218     brouard  2832: /*************** backward transition probabilities ***************/ 
                   2833: 
                   2834:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2835: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2836:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2837: {
1.222     brouard  2838:   /* Computes the backward probability at age agefin and covariate ij
                   2839:    * and returns in **ps as well as **bmij.
                   2840:    */
1.218     brouard  2841:   int i, ii, j,k;
1.222     brouard  2842:   
                   2843:   double **out, **pmij();
                   2844:   double sumnew=0.;
1.218     brouard  2845:   double agefin;
1.222     brouard  2846:   
                   2847:   double **dnewm, **dsavm, **doldm;
                   2848:   double **bbmij;
                   2849:   
1.218     brouard  2850:   doldm=ddoldms; /* global pointers */
1.222     brouard  2851:   dnewm=ddnewms;
                   2852:   dsavm=ddsavms;
                   2853:   
                   2854:   agefin=cov[2];
                   2855:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
                   2856:      the observed prevalence (with this covariate ij) */
                   2857:   dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate);
                   2858:   /* We do have the matrix Px in savm  and we need pij */
                   2859:   for (j=1;j<=nlstate+ndeath;j++){
                   2860:     sumnew=0.; /* w1 p11 + w2 p21 only on live states */
                   2861:     for (ii=1;ii<=nlstate;ii++){
                   2862:       sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij];
                   2863:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
                   2864:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2865:       if(sumnew >= 1.e-10){
                   2866:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
                   2867:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2868:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
                   2869:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2870:        /* }else */
                   2871:        doldm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2872:       }else{
1.242     brouard  2873:        ;
                   2874:        /* printf("ii=%d, i=%d, doldm=%lf dsavm=%lf, probs=%lf, sumnew=%lf,agefin=%d\n",ii,j,doldm[ii][j],dsavm[ii][j],prevacurrent[(int)agefin][ii][ij],sumnew, (int)agefin); */
1.222     brouard  2875:       }
                   2876:     } /*End ii */
                   2877:   } /* End j, At the end doldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2878:   /* left Product of this diag matrix by dsavm=Px (newm=dsavm*doldm) */
                   2879:   bbmij=matprod2(dnewm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, doldm); /* Bug Valgrind */
                   2880:   /* dsavm=doldm; /\* dsavm is now diag [1/(w_1p1i+w_2 p2i)] but can be overwritten*\/ */
                   2881:   /* doldm=dnewm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2882:   /* dnewm=dsavm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2883:   /* left Product of this matrix by diag matrix of prevalences (savm) */
                   2884:   for (j=1;j<=nlstate+ndeath;j++){
                   2885:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2886:       dsavm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij] : 0.0);
                   2887:     }
                   2888:   } /* End j, At the end oldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2889:   ps=matprod2(doldm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dnewm); /* Bug Valgrind */
                   2890:   /* newm or out is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
                   2891:   /* end bmij */
                   2892:   return ps; 
1.218     brouard  2893: }
1.217     brouard  2894: /*************** transition probabilities ***************/ 
                   2895: 
1.218     brouard  2896: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2897: {
                   2898:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2899:      computes the probability to be observed in state j being in state i by appying the
                   2900:      model to the ncovmodel covariates (including constant and age).
                   2901:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2902:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2903:      ncth covariate in the global vector x is given by the formula:
                   2904:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2905:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2906:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2907:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2908:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2909:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2910:   */
                   2911:   double s1, lnpijopii;
                   2912:   /*double t34;*/
                   2913:   int i,j, nc, ii, jj;
                   2914: 
1.234     brouard  2915:   for(i=1; i<= nlstate; i++){
                   2916:     for(j=1; j<i;j++){
                   2917:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2918:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2919:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2920:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2921:       }
                   2922:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2923:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2924:     }
                   2925:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2926:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2927:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2928:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2929:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2930:       }
                   2931:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2932:     }
                   2933:   }
                   2934:   
                   2935:   for(i=1; i<= nlstate; i++){
                   2936:     s1=0;
                   2937:     for(j=1; j<i; j++){
                   2938:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2939:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2940:     }
                   2941:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2942:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2943:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2944:     }
                   2945:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2946:     ps[i][i]=1./(s1+1.);
                   2947:     /* Computing other pijs */
                   2948:     for(j=1; j<i; j++)
                   2949:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2950:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2951:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2952:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2953:   } /* end i */
                   2954:   
                   2955:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2956:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2957:       ps[ii][jj]=0;
                   2958:       ps[ii][ii]=1;
                   2959:     }
                   2960:   }
                   2961:   /* Added for backcast */ /* Transposed matrix too */
                   2962:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2963:     s1=0.;
                   2964:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   2965:       s1+=ps[ii][jj];
                   2966:     }
                   2967:     for(ii=1; ii<= nlstate; ii++){
                   2968:       ps[ii][jj]=ps[ii][jj]/s1;
                   2969:     }
                   2970:   }
                   2971:   /* Transposition */
                   2972:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2973:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   2974:       s1=ps[ii][jj];
                   2975:       ps[ii][jj]=ps[jj][ii];
                   2976:       ps[jj][ii]=s1;
                   2977:     }
                   2978:   }
                   2979:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2980:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2981:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2982:   /*   } */
                   2983:   /*   printf("\n "); */
                   2984:   /* } */
                   2985:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2986:   /*
                   2987:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   2988:     goto end;*/
                   2989:   return ps;
1.217     brouard  2990: }
                   2991: 
                   2992: 
1.126     brouard  2993: /**************** Product of 2 matrices ******************/
                   2994: 
1.145     brouard  2995: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  2996: {
                   2997:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   2998:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   2999:   /* in, b, out are matrice of pointers which should have been initialized 
                   3000:      before: only the contents of out is modified. The function returns
                   3001:      a pointer to pointers identical to out */
1.145     brouard  3002:   int i, j, k;
1.126     brouard  3003:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3004:     for(k=ncolol; k<=ncoloh; k++){
                   3005:       out[i][k]=0.;
                   3006:       for(j=ncl; j<=nch; j++)
                   3007:        out[i][k] +=in[i][j]*b[j][k];
                   3008:     }
1.126     brouard  3009:   return out;
                   3010: }
                   3011: 
                   3012: 
                   3013: /************* Higher Matrix Product ***************/
                   3014: 
1.235     brouard  3015: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3016: {
1.218     brouard  3017:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3018:      'nhstepm*hstepm*stepm' months (i.e. until
                   3019:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3020:      nhstepm*hstepm matrices. 
                   3021:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3022:      (typically every 2 years instead of every month which is too big 
                   3023:      for the memory).
                   3024:      Model is determined by parameters x and covariates have to be 
                   3025:      included manually here. 
                   3026: 
                   3027:      */
                   3028: 
                   3029:   int i, j, d, h, k;
1.131     brouard  3030:   double **out, cov[NCOVMAX+1];
1.126     brouard  3031:   double **newm;
1.187     brouard  3032:   double agexact;
1.214     brouard  3033:   double agebegin, ageend;
1.126     brouard  3034: 
                   3035:   /* Hstepm could be zero and should return the unit matrix */
                   3036:   for (i=1;i<=nlstate+ndeath;i++)
                   3037:     for (j=1;j<=nlstate+ndeath;j++){
                   3038:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3039:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3040:     }
                   3041:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3042:   for(h=1; h <=nhstepm; h++){
                   3043:     for(d=1; d <=hstepm; d++){
                   3044:       newm=savm;
                   3045:       /* Covariates have to be included here again */
                   3046:       cov[1]=1.;
1.214     brouard  3047:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3048:       cov[2]=agexact;
                   3049:       if(nagesqr==1)
1.227     brouard  3050:        cov[3]= agexact*agexact;
1.235     brouard  3051:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3052:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3053:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3054:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3055:       }
                   3056:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3057:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3058:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3059:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3060:       }
                   3061:       for (k=1; k<=cptcovage;k++){
                   3062:        if(Dummy[Tvar[Tage[k]]]){
                   3063:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3064:        } else{
                   3065:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3066:        }
                   3067:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3068:       }
                   3069:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3070:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3071:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3072:       }
                   3073:       /* for (k=1; k<=cptcovn;k++)  */
                   3074:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3075:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3076:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3077:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3078:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3079:       
                   3080:       
1.126     brouard  3081:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3082:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3083:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3084:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3085:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3086:       /* if((int)age == 70){ */
                   3087:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3088:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3089:       /*         printf("%d pmmij ",i); */
                   3090:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3091:       /*           printf("%f ",pmmij[i][j]); */
                   3092:       /*         } */
                   3093:       /*         printf(" oldm "); */
                   3094:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3095:       /*           printf("%f ",oldm[i][j]); */
                   3096:       /*         } */
                   3097:       /*         printf("\n"); */
                   3098:       /*       } */
                   3099:       /* } */
1.126     brouard  3100:       savm=oldm;
                   3101:       oldm=newm;
                   3102:     }
                   3103:     for(i=1; i<=nlstate+ndeath; i++)
                   3104:       for(j=1;j<=nlstate+ndeath;j++) {
1.218     brouard  3105:                                po[i][j][h]=newm[i][j];
                   3106:                                /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3107:       }
1.128     brouard  3108:     /*printf("h=%d ",h);*/
1.126     brouard  3109:   } /* end h */
1.218     brouard  3110:        /*     printf("\n H=%d \n",h); */
1.126     brouard  3111:   return po;
                   3112: }
                   3113: 
1.217     brouard  3114: /************* Higher Back Matrix Product ***************/
1.218     brouard  3115: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.222     brouard  3116: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij )
1.217     brouard  3117: {
1.218     brouard  3118:   /* Computes the transition matrix starting at age 'age' over
1.217     brouard  3119:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3120:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3121:      nhstepm*hstepm matrices.
                   3122:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3123:      (typically every 2 years instead of every month which is too big
1.217     brouard  3124:      for the memory).
1.218     brouard  3125:      Model is determined by parameters x and covariates have to be
                   3126:      included manually here.
1.217     brouard  3127: 
1.222     brouard  3128:   */
1.217     brouard  3129: 
                   3130:   int i, j, d, h, k;
                   3131:   double **out, cov[NCOVMAX+1];
                   3132:   double **newm;
                   3133:   double agexact;
                   3134:   double agebegin, ageend;
1.222     brouard  3135:   double **oldm, **savm;
1.217     brouard  3136: 
1.222     brouard  3137:   oldm=oldms;savm=savms;
1.217     brouard  3138:   /* Hstepm could be zero and should return the unit matrix */
                   3139:   for (i=1;i<=nlstate+ndeath;i++)
                   3140:     for (j=1;j<=nlstate+ndeath;j++){
                   3141:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3142:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3143:     }
                   3144:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3145:   for(h=1; h <=nhstepm; h++){
                   3146:     for(d=1; d <=hstepm; d++){
                   3147:       newm=savm;
                   3148:       /* Covariates have to be included here again */
                   3149:       cov[1]=1.;
                   3150:       agexact=age-((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
                   3151:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3152:       cov[2]=agexact;
                   3153:       if(nagesqr==1)
1.222     brouard  3154:        cov[3]= agexact*agexact;
1.218     brouard  3155:       for (k=1; k<=cptcovn;k++)
1.222     brouard  3156:        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   3157:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.217     brouard  3158:       for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
1.222     brouard  3159:        /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   3160:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3161:       /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
1.217     brouard  3162:       for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
1.222     brouard  3163:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3164:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
1.218     brouard  3165:                        
                   3166:                        
1.217     brouard  3167:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3168:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3169:       /* Careful transposed matrix */
1.222     brouard  3170:       /* age is in cov[2] */
1.218     brouard  3171:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3172:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3173:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3174:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3175:       /* if((int)age == 70){ */
                   3176:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3177:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3178:       /*         printf("%d pmmij ",i); */
                   3179:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3180:       /*           printf("%f ",pmmij[i][j]); */
                   3181:       /*         } */
                   3182:       /*         printf(" oldm "); */
                   3183:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3184:       /*           printf("%f ",oldm[i][j]); */
                   3185:       /*         } */
                   3186:       /*         printf("\n"); */
                   3187:       /*       } */
                   3188:       /* } */
                   3189:       savm=oldm;
                   3190:       oldm=newm;
                   3191:     }
                   3192:     for(i=1; i<=nlstate+ndeath; i++)
                   3193:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3194:        po[i][j][h]=newm[i][j];
                   3195:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.217     brouard  3196:       }
                   3197:     /*printf("h=%d ",h);*/
                   3198:   } /* end h */
1.222     brouard  3199:   /*     printf("\n H=%d \n",h); */
1.217     brouard  3200:   return po;
                   3201: }
                   3202: 
                   3203: 
1.162     brouard  3204: #ifdef NLOPT
                   3205:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3206:   double fret;
                   3207:   double *xt;
                   3208:   int j;
                   3209:   myfunc_data *d2 = (myfunc_data *) pd;
                   3210: /* xt = (p1-1); */
                   3211:   xt=vector(1,n); 
                   3212:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3213: 
                   3214:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3215:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3216:   printf("Function = %.12lf ",fret);
                   3217:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3218:   printf("\n");
                   3219:  free_vector(xt,1,n);
                   3220:   return fret;
                   3221: }
                   3222: #endif
1.126     brouard  3223: 
                   3224: /*************** log-likelihood *************/
                   3225: double func( double *x)
                   3226: {
1.226     brouard  3227:   int i, ii, j, k, mi, d, kk;
                   3228:   int ioffset=0;
                   3229:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3230:   double **out;
                   3231:   double lli; /* Individual log likelihood */
                   3232:   int s1, s2;
1.228     brouard  3233:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3234:   double bbh, survp;
                   3235:   long ipmx;
                   3236:   double agexact;
                   3237:   /*extern weight */
                   3238:   /* We are differentiating ll according to initial status */
                   3239:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3240:   /*for(i=1;i<imx;i++) 
                   3241:     printf(" %d\n",s[4][i]);
                   3242:   */
1.162     brouard  3243: 
1.226     brouard  3244:   ++countcallfunc;
1.162     brouard  3245: 
1.226     brouard  3246:   cov[1]=1.;
1.126     brouard  3247: 
1.226     brouard  3248:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3249:   ioffset=0;
1.226     brouard  3250:   if(mle==1){
                   3251:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3252:       /* Computes the values of the ncovmodel covariates of the model
                   3253:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3254:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3255:         to be observed in j being in i according to the model.
                   3256:       */
1.243     brouard  3257:       ioffset=2+nagesqr ;
1.233     brouard  3258:    /* Fixed */
1.234     brouard  3259:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3260:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3261:       }
1.226     brouard  3262:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3263:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3264:         has been calculated etc */
                   3265:       /* For an individual i, wav[i] gives the number of effective waves */
                   3266:       /* We compute the contribution to Likelihood of each effective transition
                   3267:         mw[mi][i] is real wave of the mi th effectve wave */
                   3268:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3269:         s2=s[mw[mi+1][i]][i];
                   3270:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3271:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3272:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3273:       */
                   3274:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3275:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3276:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3277:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3278:        }
                   3279:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3280:          for (j=1;j<=nlstate+ndeath;j++){
                   3281:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3282:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3283:          }
                   3284:        for(d=0; d<dh[mi][i]; d++){
                   3285:          newm=savm;
                   3286:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3287:          cov[2]=agexact;
                   3288:          if(nagesqr==1)
                   3289:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3290:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3291:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3292:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3293:          else
                   3294:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3295:          }
                   3296:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3297:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3298:          savm=oldm;
                   3299:          oldm=newm;
                   3300:        } /* end mult */
                   3301:        
                   3302:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3303:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3304:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3305:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3306:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3307:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3308:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3309:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3310:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3311:                                 * -stepm/2 to stepm/2 .
                   3312:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3313:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3314:                                 */
1.234     brouard  3315:        s1=s[mw[mi][i]][i];
                   3316:        s2=s[mw[mi+1][i]][i];
                   3317:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3318:        /* bias bh is positive if real duration
                   3319:         * is higher than the multiple of stepm and negative otherwise.
                   3320:         */
                   3321:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3322:        if( s2 > nlstate){ 
                   3323:          /* i.e. if s2 is a death state and if the date of death is known 
                   3324:             then the contribution to the likelihood is the probability to 
                   3325:             die between last step unit time and current  step unit time, 
                   3326:             which is also equal to probability to die before dh 
                   3327:             minus probability to die before dh-stepm . 
                   3328:             In version up to 0.92 likelihood was computed
                   3329:             as if date of death was unknown. Death was treated as any other
                   3330:             health state: the date of the interview describes the actual state
                   3331:             and not the date of a change in health state. The former idea was
                   3332:             to consider that at each interview the state was recorded
                   3333:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3334:             introduced the exact date of death then we should have modified
                   3335:             the contribution of an exact death to the likelihood. This new
                   3336:             contribution is smaller and very dependent of the step unit
                   3337:             stepm. It is no more the probability to die between last interview
                   3338:             and month of death but the probability to survive from last
                   3339:             interview up to one month before death multiplied by the
                   3340:             probability to die within a month. Thanks to Chris
                   3341:             Jackson for correcting this bug.  Former versions increased
                   3342:             mortality artificially. The bad side is that we add another loop
                   3343:             which slows down the processing. The difference can be up to 10%
                   3344:             lower mortality.
                   3345:          */
                   3346:          /* If, at the beginning of the maximization mostly, the
                   3347:             cumulative probability or probability to be dead is
                   3348:             constant (ie = 1) over time d, the difference is equal to
                   3349:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3350:             s1 at precedent wave, to be dead a month before current
                   3351:             wave is equal to probability, being at state s1 at
                   3352:             precedent wave, to be dead at mont of the current
                   3353:             wave. Then the observed probability (that this person died)
                   3354:             is null according to current estimated parameter. In fact,
                   3355:             it should be very low but not zero otherwise the log go to
                   3356:             infinity.
                   3357:          */
1.183     brouard  3358: /* #ifdef INFINITYORIGINAL */
                   3359: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3360: /* #else */
                   3361: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3362: /*         lli=log(mytinydouble); */
                   3363: /*       else */
                   3364: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3365: /* #endif */
1.226     brouard  3366:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3367:          
1.226     brouard  3368:        } else if  ( s2==-1 ) { /* alive */
                   3369:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3370:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3371:          /*survp += out[s1][j]; */
                   3372:          lli= log(survp);
                   3373:        }
                   3374:        else if  (s2==-4) { 
                   3375:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3376:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3377:          lli= log(survp); 
                   3378:        } 
                   3379:        else if  (s2==-5) { 
                   3380:          for (j=1,survp=0. ; j<=2; j++)  
                   3381:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3382:          lli= log(survp); 
                   3383:        } 
                   3384:        else{
                   3385:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3386:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3387:        } 
                   3388:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3389:        /*if(lli ==000.0)*/
                   3390:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3391:        ipmx +=1;
                   3392:        sw += weight[i];
                   3393:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3394:        /* if (lli < log(mytinydouble)){ */
                   3395:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3396:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3397:        /* } */
                   3398:       } /* end of wave */
                   3399:     } /* end of individual */
                   3400:   }  else if(mle==2){
                   3401:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3402:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3403:       for(mi=1; mi<= wav[i]-1; mi++){
                   3404:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3405:          for (j=1;j<=nlstate+ndeath;j++){
                   3406:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3407:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3408:          }
                   3409:        for(d=0; d<=dh[mi][i]; d++){
                   3410:          newm=savm;
                   3411:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3412:          cov[2]=agexact;
                   3413:          if(nagesqr==1)
                   3414:            cov[3]= agexact*agexact;
                   3415:          for (kk=1; kk<=cptcovage;kk++) {
                   3416:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3417:          }
                   3418:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3419:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3420:          savm=oldm;
                   3421:          oldm=newm;
                   3422:        } /* end mult */
                   3423:       
                   3424:        s1=s[mw[mi][i]][i];
                   3425:        s2=s[mw[mi+1][i]][i];
                   3426:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3427:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3428:        ipmx +=1;
                   3429:        sw += weight[i];
                   3430:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3431:       } /* end of wave */
                   3432:     } /* end of individual */
                   3433:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3434:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3435:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3436:       for(mi=1; mi<= wav[i]-1; mi++){
                   3437:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3438:          for (j=1;j<=nlstate+ndeath;j++){
                   3439:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3440:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3441:          }
                   3442:        for(d=0; d<dh[mi][i]; d++){
                   3443:          newm=savm;
                   3444:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3445:          cov[2]=agexact;
                   3446:          if(nagesqr==1)
                   3447:            cov[3]= agexact*agexact;
                   3448:          for (kk=1; kk<=cptcovage;kk++) {
                   3449:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3450:          }
                   3451:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3452:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3453:          savm=oldm;
                   3454:          oldm=newm;
                   3455:        } /* end mult */
                   3456:       
                   3457:        s1=s[mw[mi][i]][i];
                   3458:        s2=s[mw[mi+1][i]][i];
                   3459:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3460:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3461:        ipmx +=1;
                   3462:        sw += weight[i];
                   3463:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3464:       } /* end of wave */
                   3465:     } /* end of individual */
                   3466:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3467:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3468:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3469:       for(mi=1; mi<= wav[i]-1; mi++){
                   3470:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3471:          for (j=1;j<=nlstate+ndeath;j++){
                   3472:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3473:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3474:          }
                   3475:        for(d=0; d<dh[mi][i]; d++){
                   3476:          newm=savm;
                   3477:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3478:          cov[2]=agexact;
                   3479:          if(nagesqr==1)
                   3480:            cov[3]= agexact*agexact;
                   3481:          for (kk=1; kk<=cptcovage;kk++) {
                   3482:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3483:          }
1.126     brouard  3484:        
1.226     brouard  3485:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3486:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3487:          savm=oldm;
                   3488:          oldm=newm;
                   3489:        } /* end mult */
                   3490:       
                   3491:        s1=s[mw[mi][i]][i];
                   3492:        s2=s[mw[mi+1][i]][i];
                   3493:        if( s2 > nlstate){ 
                   3494:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3495:        } else if  ( s2==-1 ) { /* alive */
                   3496:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3497:            survp += out[s1][j];
                   3498:          lli= log(survp);
                   3499:        }else{
                   3500:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3501:        }
                   3502:        ipmx +=1;
                   3503:        sw += weight[i];
                   3504:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3505: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3506:       } /* end of wave */
                   3507:     } /* end of individual */
                   3508:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3509:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3510:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3511:       for(mi=1; mi<= wav[i]-1; mi++){
                   3512:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3513:          for (j=1;j<=nlstate+ndeath;j++){
                   3514:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3515:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3516:          }
                   3517:        for(d=0; d<dh[mi][i]; d++){
                   3518:          newm=savm;
                   3519:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3520:          cov[2]=agexact;
                   3521:          if(nagesqr==1)
                   3522:            cov[3]= agexact*agexact;
                   3523:          for (kk=1; kk<=cptcovage;kk++) {
                   3524:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3525:          }
1.126     brouard  3526:        
1.226     brouard  3527:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3528:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3529:          savm=oldm;
                   3530:          oldm=newm;
                   3531:        } /* end mult */
                   3532:       
                   3533:        s1=s[mw[mi][i]][i];
                   3534:        s2=s[mw[mi+1][i]][i];
                   3535:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3536:        ipmx +=1;
                   3537:        sw += weight[i];
                   3538:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3539:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3540:       } /* end of wave */
                   3541:     } /* end of individual */
                   3542:   } /* End of if */
                   3543:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3544:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3545:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3546:   return -l;
1.126     brouard  3547: }
                   3548: 
                   3549: /*************** log-likelihood *************/
                   3550: double funcone( double *x)
                   3551: {
1.228     brouard  3552:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3553:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3554:   int ioffset=0;
1.131     brouard  3555:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3556:   double **out;
                   3557:   double lli; /* Individual log likelihood */
                   3558:   double llt;
                   3559:   int s1, s2;
1.228     brouard  3560:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3561: 
1.126     brouard  3562:   double bbh, survp;
1.187     brouard  3563:   double agexact;
1.214     brouard  3564:   double agebegin, ageend;
1.126     brouard  3565:   /*extern weight */
                   3566:   /* We are differentiating ll according to initial status */
                   3567:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3568:   /*for(i=1;i<imx;i++) 
                   3569:     printf(" %d\n",s[4][i]);
                   3570:   */
                   3571:   cov[1]=1.;
                   3572: 
                   3573:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3574:   ioffset=0;
                   3575:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3576:     /* ioffset=2+nagesqr+cptcovage; */
                   3577:     ioffset=2+nagesqr;
1.232     brouard  3578:     /* Fixed */
1.224     brouard  3579:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3580:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3581:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3582:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3583: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3584: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3585: /*    cov[2+6]=covar[2][i]; V2  */
                   3586: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3587: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3588: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3589: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3590: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3591: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3592:     }
1.232     brouard  3593:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3594:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3595:     /* } */
1.231     brouard  3596:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3597:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3598:     /* } */
1.225     brouard  3599:     
1.233     brouard  3600: 
                   3601:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3602:     /* Wave varying (but not age varying) */
                   3603:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3604:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3605:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3606:       }
1.232     brouard  3607:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3608:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3609:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3610:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3611:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3612:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3613:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3614:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3615:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3616:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3617:       /* } */
1.126     brouard  3618:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3619:        for (j=1;j<=nlstate+ndeath;j++){
                   3620:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3621:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3622:        }
1.214     brouard  3623:       
                   3624:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3625:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3626:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3627:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3628:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3629:          and mw[mi+1][i]. dh depends on stepm.*/
                   3630:        newm=savm;
1.247     brouard  3631:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3632:        cov[2]=agexact;
                   3633:        if(nagesqr==1)
                   3634:          cov[3]= agexact*agexact;
                   3635:        for (kk=1; kk<=cptcovage;kk++) {
                   3636:          if(!FixedV[Tvar[Tage[kk]]])
                   3637:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3638:          else
                   3639:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3640:        }
                   3641:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3642:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3643:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3644:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3645:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3646:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3647:        savm=oldm;
                   3648:        oldm=newm;
1.126     brouard  3649:       } /* end mult */
                   3650:       
                   3651:       s1=s[mw[mi][i]][i];
                   3652:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3653:       /* if(s2==-1){ */
                   3654:       /*       printf(" s1=%d, s2=%d i=%d \n", s1, s2, i); */
                   3655:       /*       /\* exit(1); *\/ */
                   3656:       /* } */
1.126     brouard  3657:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3658:       /* bias is positive if real duration
                   3659:        * is higher than the multiple of stepm and negative otherwise.
                   3660:        */
                   3661:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3662:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3663:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3664:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3665:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3666:        lli= log(survp);
1.126     brouard  3667:       }else if (mle==1){
1.242     brouard  3668:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3669:       } else if(mle==2){
1.242     brouard  3670:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3671:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3672:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3673:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3674:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3675:       } else{  /* mle=0 back to 1 */
1.242     brouard  3676:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3677:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3678:       } /* End of if */
                   3679:       ipmx +=1;
                   3680:       sw += weight[i];
                   3681:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3682:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3683:       if(globpr){
1.246     brouard  3684:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3685:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3686:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
                   3687:                2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
                   3688:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3689:          llt +=ll[k]*gipmx/gsw;
                   3690:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3691:        }
                   3692:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3693:       }
1.232     brouard  3694:        } /* end of wave */
                   3695: } /* end of individual */
                   3696: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3697: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3698: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3699: if(globpr==0){ /* First time we count the contributions and weights */
                   3700:        gipmx=ipmx;
                   3701:        gsw=sw;
                   3702: }
                   3703: return -l;
1.126     brouard  3704: }
                   3705: 
                   3706: 
                   3707: /*************** function likelione ***********/
                   3708: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3709: {
                   3710:   /* This routine should help understanding what is done with 
                   3711:      the selection of individuals/waves and
                   3712:      to check the exact contribution to the likelihood.
                   3713:      Plotting could be done.
                   3714:    */
                   3715:   int k;
                   3716: 
                   3717:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3718:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3719:     strcat(fileresilk,fileresu);
1.126     brouard  3720:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3721:       printf("Problem with resultfile: %s\n", fileresilk);
                   3722:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3723:     }
1.214     brouard  3724:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3725:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3726:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3727:     for(k=1; k<=nlstate; k++) 
                   3728:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3729:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3730:   }
                   3731: 
                   3732:   *fretone=(*funcone)(p);
                   3733:   if(*globpri !=0){
                   3734:     fclose(ficresilk);
1.205     brouard  3735:     if (mle ==0)
                   3736:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3737:     else if(mle >=1)
                   3738:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3739:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3740:     
1.208     brouard  3741:       
                   3742:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3743:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3744: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3745:     }
1.207     brouard  3746:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3747: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3748:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3749: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3750:     fflush(fichtm);
1.205     brouard  3751:   }
1.126     brouard  3752:   return;
                   3753: }
                   3754: 
                   3755: 
                   3756: /*********** Maximum Likelihood Estimation ***************/
                   3757: 
                   3758: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3759: {
1.165     brouard  3760:   int i,j, iter=0;
1.126     brouard  3761:   double **xi;
                   3762:   double fret;
                   3763:   double fretone; /* Only one call to likelihood */
                   3764:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3765: 
                   3766: #ifdef NLOPT
                   3767:   int creturn;
                   3768:   nlopt_opt opt;
                   3769:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3770:   double *lb;
                   3771:   double minf; /* the minimum objective value, upon return */
                   3772:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3773:   myfunc_data dinst, *d = &dinst;
                   3774: #endif
                   3775: 
                   3776: 
1.126     brouard  3777:   xi=matrix(1,npar,1,npar);
                   3778:   for (i=1;i<=npar;i++)
                   3779:     for (j=1;j<=npar;j++)
                   3780:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3781:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3782:   strcpy(filerespow,"POW_"); 
1.126     brouard  3783:   strcat(filerespow,fileres);
                   3784:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3785:     printf("Problem with resultfile: %s\n", filerespow);
                   3786:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3787:   }
                   3788:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3789:   for (i=1;i<=nlstate;i++)
                   3790:     for(j=1;j<=nlstate+ndeath;j++)
                   3791:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3792:   fprintf(ficrespow,"\n");
1.162     brouard  3793: #ifdef POWELL
1.126     brouard  3794:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3795: #endif
1.126     brouard  3796: 
1.162     brouard  3797: #ifdef NLOPT
                   3798: #ifdef NEWUOA
                   3799:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3800: #else
                   3801:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3802: #endif
                   3803:   lb=vector(0,npar-1);
                   3804:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3805:   nlopt_set_lower_bounds(opt, lb);
                   3806:   nlopt_set_initial_step1(opt, 0.1);
                   3807:   
                   3808:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3809:   d->function = func;
                   3810:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3811:   nlopt_set_min_objective(opt, myfunc, d);
                   3812:   nlopt_set_xtol_rel(opt, ftol);
                   3813:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3814:     printf("nlopt failed! %d\n",creturn); 
                   3815:   }
                   3816:   else {
                   3817:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3818:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3819:     iter=1; /* not equal */
                   3820:   }
                   3821:   nlopt_destroy(opt);
                   3822: #endif
1.126     brouard  3823:   free_matrix(xi,1,npar,1,npar);
                   3824:   fclose(ficrespow);
1.203     brouard  3825:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3826:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3827:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3828: 
                   3829: }
                   3830: 
                   3831: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3832: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3833: {
                   3834:   double  **a,**y,*x,pd;
1.203     brouard  3835:   /* double **hess; */
1.164     brouard  3836:   int i, j;
1.126     brouard  3837:   int *indx;
                   3838: 
                   3839:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3840:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3841:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3842:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3843:   double gompertz(double p[]);
1.203     brouard  3844:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3845: 
                   3846:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3847:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3848:   for (i=1;i<=npar;i++){
1.203     brouard  3849:     printf("%d-",i);fflush(stdout);
                   3850:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3851:    
                   3852:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3853:     
                   3854:     /*  printf(" %f ",p[i]);
                   3855:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3856:   }
                   3857:   
                   3858:   for (i=1;i<=npar;i++) {
                   3859:     for (j=1;j<=npar;j++)  {
                   3860:       if (j>i) { 
1.203     brouard  3861:        printf(".%d-%d",i,j);fflush(stdout);
                   3862:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3863:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3864:        
                   3865:        hess[j][i]=hess[i][j];    
                   3866:        /*printf(" %lf ",hess[i][j]);*/
                   3867:       }
                   3868:     }
                   3869:   }
                   3870:   printf("\n");
                   3871:   fprintf(ficlog,"\n");
                   3872: 
                   3873:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3874:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3875:   
                   3876:   a=matrix(1,npar,1,npar);
                   3877:   y=matrix(1,npar,1,npar);
                   3878:   x=vector(1,npar);
                   3879:   indx=ivector(1,npar);
                   3880:   for (i=1;i<=npar;i++)
                   3881:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3882:   ludcmp(a,npar,indx,&pd);
                   3883: 
                   3884:   for (j=1;j<=npar;j++) {
                   3885:     for (i=1;i<=npar;i++) x[i]=0;
                   3886:     x[j]=1;
                   3887:     lubksb(a,npar,indx,x);
                   3888:     for (i=1;i<=npar;i++){ 
                   3889:       matcov[i][j]=x[i];
                   3890:     }
                   3891:   }
                   3892: 
                   3893:   printf("\n#Hessian matrix#\n");
                   3894:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   3895:   for (i=1;i<=npar;i++) { 
                   3896:     for (j=1;j<=npar;j++) { 
1.203     brouard  3897:       printf("%.6e ",hess[i][j]);
                   3898:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  3899:     }
                   3900:     printf("\n");
                   3901:     fprintf(ficlog,"\n");
                   3902:   }
                   3903: 
1.203     brouard  3904:   /* printf("\n#Covariance matrix#\n"); */
                   3905:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   3906:   /* for (i=1;i<=npar;i++) {  */
                   3907:   /*   for (j=1;j<=npar;j++) {  */
                   3908:   /*     printf("%.6e ",matcov[i][j]); */
                   3909:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   3910:   /*   } */
                   3911:   /*   printf("\n"); */
                   3912:   /*   fprintf(ficlog,"\n"); */
                   3913:   /* } */
                   3914: 
1.126     brouard  3915:   /* Recompute Inverse */
1.203     brouard  3916:   /* for (i=1;i<=npar;i++) */
                   3917:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   3918:   /* ludcmp(a,npar,indx,&pd); */
                   3919: 
                   3920:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   3921: 
                   3922:   /* for (j=1;j<=npar;j++) { */
                   3923:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   3924:   /*   x[j]=1; */
                   3925:   /*   lubksb(a,npar,indx,x); */
                   3926:   /*   for (i=1;i<=npar;i++){  */
                   3927:   /*     y[i][j]=x[i]; */
                   3928:   /*     printf("%.3e ",y[i][j]); */
                   3929:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   3930:   /*   } */
                   3931:   /*   printf("\n"); */
                   3932:   /*   fprintf(ficlog,"\n"); */
                   3933:   /* } */
                   3934: 
                   3935:   /* Verifying the inverse matrix */
                   3936: #ifdef DEBUGHESS
                   3937:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  3938: 
1.203     brouard  3939:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   3940:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  3941: 
                   3942:   for (j=1;j<=npar;j++) {
                   3943:     for (i=1;i<=npar;i++){ 
1.203     brouard  3944:       printf("%.2f ",y[i][j]);
                   3945:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  3946:     }
                   3947:     printf("\n");
                   3948:     fprintf(ficlog,"\n");
                   3949:   }
1.203     brouard  3950: #endif
1.126     brouard  3951: 
                   3952:   free_matrix(a,1,npar,1,npar);
                   3953:   free_matrix(y,1,npar,1,npar);
                   3954:   free_vector(x,1,npar);
                   3955:   free_ivector(indx,1,npar);
1.203     brouard  3956:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  3957: 
                   3958: 
                   3959: }
                   3960: 
                   3961: /*************** hessian matrix ****************/
                   3962: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  3963: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  3964:   int i;
                   3965:   int l=1, lmax=20;
1.203     brouard  3966:   double k1,k2, res, fx;
1.132     brouard  3967:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  3968:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   3969:   int k=0,kmax=10;
                   3970:   double l1;
                   3971: 
                   3972:   fx=func(x);
                   3973:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  3974:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  3975:     l1=pow(10,l);
                   3976:     delts=delt;
                   3977:     for(k=1 ; k <kmax; k=k+1){
                   3978:       delt = delta*(l1*k);
                   3979:       p2[theta]=x[theta] +delt;
1.145     brouard  3980:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  3981:       p2[theta]=x[theta]-delt;
                   3982:       k2=func(p2)-fx;
                   3983:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  3984:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  3985:       
1.203     brouard  3986: #ifdef DEBUGHESSII
1.126     brouard  3987:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3988:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3989: #endif
                   3990:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   3991:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   3992:        k=kmax;
                   3993:       }
                   3994:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  3995:        k=kmax; l=lmax*10;
1.126     brouard  3996:       }
                   3997:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   3998:        delts=delt;
                   3999:       }
1.203     brouard  4000:     } /* End loop k */
1.126     brouard  4001:   }
                   4002:   delti[theta]=delts;
                   4003:   return res; 
                   4004:   
                   4005: }
                   4006: 
1.203     brouard  4007: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4008: {
                   4009:   int i;
1.164     brouard  4010:   int l=1, lmax=20;
1.126     brouard  4011:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4012:   double p2[MAXPARM+1];
1.203     brouard  4013:   int k, kmax=1;
                   4014:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4015: 
                   4016:   int firstime=0;
1.203     brouard  4017:   
1.126     brouard  4018:   fx=func(x);
1.203     brouard  4019:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4020:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4021:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4022:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4023:     k1=func(p2)-fx;
                   4024:   
1.203     brouard  4025:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4026:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4027:     k2=func(p2)-fx;
                   4028:   
1.203     brouard  4029:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4030:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4031:     k3=func(p2)-fx;
                   4032:   
1.203     brouard  4033:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4034:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4035:     k4=func(p2)-fx;
1.203     brouard  4036:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4037:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4038:       firstime=1;
1.203     brouard  4039:       kmax=kmax+10;
1.208     brouard  4040:     }
                   4041:     if(kmax >=10 || firstime ==1){
1.246     brouard  4042:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4043:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4044:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4045:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4046:     }
                   4047: #ifdef DEBUGHESSIJ
                   4048:     v1=hess[thetai][thetai];
                   4049:     v2=hess[thetaj][thetaj];
                   4050:     cv12=res;
                   4051:     /* Computing eigen value of Hessian matrix */
                   4052:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4053:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4054:     if ((lc2 <0) || (lc1 <0) ){
                   4055:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4056:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4057:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4058:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4059:     }
1.126     brouard  4060: #endif
                   4061:   }
                   4062:   return res;
                   4063: }
                   4064: 
1.203     brouard  4065:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4066: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4067: /* { */
                   4068: /*   int i; */
                   4069: /*   int l=1, lmax=20; */
                   4070: /*   double k1,k2,k3,k4,res,fx; */
                   4071: /*   double p2[MAXPARM+1]; */
                   4072: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4073: /*   int k=0,kmax=10; */
                   4074: /*   double l1; */
                   4075:   
                   4076: /*   fx=func(x); */
                   4077: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4078: /*     l1=pow(10,l); */
                   4079: /*     delts=delt; */
                   4080: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4081: /*       delt = delti*(l1*k); */
                   4082: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4083: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4084: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4085: /*       k1=func(p2)-fx; */
                   4086:       
                   4087: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4088: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4089: /*       k2=func(p2)-fx; */
                   4090:       
                   4091: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4092: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4093: /*       k3=func(p2)-fx; */
                   4094:       
                   4095: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4096: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4097: /*       k4=func(p2)-fx; */
                   4098: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4099: /* #ifdef DEBUGHESSIJ */
                   4100: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4101: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4102: /* #endif */
                   4103: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4104: /*     k=kmax; */
                   4105: /*       } */
                   4106: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4107: /*     k=kmax; l=lmax*10; */
                   4108: /*       } */
                   4109: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4110: /*     delts=delt; */
                   4111: /*       } */
                   4112: /*     } /\* End loop k *\/ */
                   4113: /*   } */
                   4114: /*   delti[theta]=delts; */
                   4115: /*   return res;  */
                   4116: /* } */
                   4117: 
                   4118: 
1.126     brouard  4119: /************** Inverse of matrix **************/
                   4120: void ludcmp(double **a, int n, int *indx, double *d) 
                   4121: { 
                   4122:   int i,imax,j,k; 
                   4123:   double big,dum,sum,temp; 
                   4124:   double *vv; 
                   4125:  
                   4126:   vv=vector(1,n); 
                   4127:   *d=1.0; 
                   4128:   for (i=1;i<=n;i++) { 
                   4129:     big=0.0; 
                   4130:     for (j=1;j<=n;j++) 
                   4131:       if ((temp=fabs(a[i][j])) > big) big=temp; 
                   4132:     if (big == 0.0) nrerror("Singular matrix in routine ludcmp"); 
                   4133:     vv[i]=1.0/big; 
                   4134:   } 
                   4135:   for (j=1;j<=n;j++) { 
                   4136:     for (i=1;i<j;i++) { 
                   4137:       sum=a[i][j]; 
                   4138:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4139:       a[i][j]=sum; 
                   4140:     } 
                   4141:     big=0.0; 
                   4142:     for (i=j;i<=n;i++) { 
                   4143:       sum=a[i][j]; 
                   4144:       for (k=1;k<j;k++) 
                   4145:        sum -= a[i][k]*a[k][j]; 
                   4146:       a[i][j]=sum; 
                   4147:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4148:        big=dum; 
                   4149:        imax=i; 
                   4150:       } 
                   4151:     } 
                   4152:     if (j != imax) { 
                   4153:       for (k=1;k<=n;k++) { 
                   4154:        dum=a[imax][k]; 
                   4155:        a[imax][k]=a[j][k]; 
                   4156:        a[j][k]=dum; 
                   4157:       } 
                   4158:       *d = -(*d); 
                   4159:       vv[imax]=vv[j]; 
                   4160:     } 
                   4161:     indx[j]=imax; 
                   4162:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4163:     if (j != n) { 
                   4164:       dum=1.0/(a[j][j]); 
                   4165:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4166:     } 
                   4167:   } 
                   4168:   free_vector(vv,1,n);  /* Doesn't work */
                   4169: ;
                   4170: } 
                   4171: 
                   4172: void lubksb(double **a, int n, int *indx, double b[]) 
                   4173: { 
                   4174:   int i,ii=0,ip,j; 
                   4175:   double sum; 
                   4176:  
                   4177:   for (i=1;i<=n;i++) { 
                   4178:     ip=indx[i]; 
                   4179:     sum=b[ip]; 
                   4180:     b[ip]=b[i]; 
                   4181:     if (ii) 
                   4182:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4183:     else if (sum) ii=i; 
                   4184:     b[i]=sum; 
                   4185:   } 
                   4186:   for (i=n;i>=1;i--) { 
                   4187:     sum=b[i]; 
                   4188:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4189:     b[i]=sum/a[i][i]; 
                   4190:   } 
                   4191: } 
                   4192: 
                   4193: void pstamp(FILE *fichier)
                   4194: {
1.196     brouard  4195:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4196: }
                   4197: 
1.253     brouard  4198: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4199: 
                   4200:   /* y=a+bx regression */
                   4201:   double   sumx = 0.0;                        /* sum of x                      */
                   4202:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4203:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4204:   double   sumy = 0.0;                        /* sum of y                      */
                   4205:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4206:   double   sume2; /* sum of square or residuals */
                   4207:   double yhat;
                   4208:   
                   4209:   double denom=0;
                   4210:   int i;
                   4211:   int ne=*no;
                   4212:   
                   4213:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4214:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4215:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4216:       continue;
                   4217:     }
                   4218:     ne=ne+1;
                   4219:     sumx  += x[i];       
                   4220:     sumx2 += x[i]*x[i];  
                   4221:     sumxy += x[i] * y[i];
                   4222:     sumy  += y[i];      
                   4223:     sumy2 += y[i]*y[i]; 
                   4224:     denom = (ne * sumx2 - sumx*sumx);
                   4225:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4226:   } 
                   4227:   
                   4228:   denom = (ne * sumx2 - sumx*sumx);
                   4229:   if (denom == 0) {
                   4230:     // vertical, slope m is infinity
                   4231:     *b = INFINITY;
                   4232:     *a = 0;
                   4233:     if (r) *r = 0;
                   4234:     return 1;
                   4235:   }
                   4236:   
                   4237:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   4238:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   4239:   if (r!=NULL) {
                   4240:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   4241:       sqrt((sumx2 - sumx*sumx/ne) *
                   4242:           (sumy2 - sumy*sumy/ne));
                   4243:   }
                   4244:   *no=ne;
                   4245:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4246:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4247:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4248:       continue;
                   4249:     }
                   4250:     ne=ne+1;
                   4251:     yhat = y[i] - *a -*b* x[i];
                   4252:     sume2  += yhat * yhat ;       
                   4253:     
                   4254:     denom = (ne * sumx2 - sumx*sumx);
                   4255:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4256:   } 
                   4257:   *sb = sqrt(sume2/(ne-2)/(sumx2 - sumx * sumx /ne));
                   4258:   *sa= *sb * sqrt(sumx2/ne);
                   4259:   
                   4260:   return 0; 
                   4261: }
                   4262: 
1.126     brouard  4263: /************ Frequencies ********************/
1.251     brouard  4264: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4265:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4266:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4267: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4268:   
1.253     brouard  4269:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0;
1.226     brouard  4270:   int iind=0, iage=0;
                   4271:   int mi; /* Effective wave */
                   4272:   int first;
                   4273:   double ***freq; /* Frequencies */
1.253     brouard  4274:   double *x, *y, a,b,r, sa, sb; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4275:   int no;
1.226     brouard  4276:   double *meanq;
                   4277:   double **meanqt;
                   4278:   double *pp, **prop, *posprop, *pospropt;
                   4279:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4280:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4281:   double agebegin, ageend;
                   4282:     
                   4283:   pp=vector(1,nlstate);
1.251     brouard  4284:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4285:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4286:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4287:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4288:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4289:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4290:   strcpy(fileresp,"P_");
                   4291:   strcat(fileresp,fileresu);
                   4292:   /*strcat(fileresphtm,fileresu);*/
                   4293:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4294:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4295:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4296:     exit(0);
                   4297:   }
1.240     brouard  4298:   
1.226     brouard  4299:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4300:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4301:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4302:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4303:     fflush(ficlog);
                   4304:     exit(70); 
                   4305:   }
                   4306:   else{
                   4307:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4308: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4309: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4310:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4311:   }
1.237     brouard  4312:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4313:   
1.226     brouard  4314:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4315:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4316:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4317:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4318:     fflush(ficlog);
                   4319:     exit(70); 
1.240     brouard  4320:   } else{
1.226     brouard  4321:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4322: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4323: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4324:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4325:   }
1.240     brouard  4326:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4327:   
1.253     brouard  4328:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4329:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4330:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4331:   j1=0;
1.126     brouard  4332:   
1.227     brouard  4333:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4334:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4335:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4336:   
                   4337:   
1.226     brouard  4338:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4339:      reference=low_education V1=0,V2=0
                   4340:      med_educ                V1=1 V2=0, 
                   4341:      high_educ               V1=0 V2=1
                   4342:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4343:   */
1.249     brouard  4344:   dateintsum=0;
                   4345:   k2cpt=0;
                   4346: 
1.253     brouard  4347:   if(cptcoveff == 0 )
                   4348:     nl=1;  /* Constant model only */
                   4349:   else
                   4350:     nl=2;
                   4351:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4352:     if(nj==1)
                   4353:       j=0;  /* First pass for the constant */
                   4354:     else
                   4355:       j=cptcoveff; /* Other passes for the covariate values */
1.251     brouard  4356:     first=1;
                   4357:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on covariates combination in order of model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
                   4358:       posproptt=0.;
                   4359:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4360:        scanf("%d", i);*/
                   4361:       for (i=-5; i<=nlstate+ndeath; i++)  
                   4362:        for (jk=-5; jk<=nlstate+ndeath; jk++)  
                   4363:          for(m=iagemin; m <= iagemax+3; m++)
                   4364:            freq[i][jk][m]=0;
                   4365:       
                   4366:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4367:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4368:          prop[i][m]=0;
                   4369:        posprop[i]=0;
                   4370:        pospropt[i]=0;
                   4371:       }
                   4372:       /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4373:       /*   meanq[z1]+=0.; */
                   4374:       /*   for(m=1;m<=lastpass;m++){ */
                   4375:       /*       meanqt[m][z1]=0.; */
                   4376:       /*   } */
                   4377:       /* } */
                   4378:       
                   4379:       /* dateintsum=0; */
                   4380:       /* k2cpt=0; */
                   4381:       
                   4382:       /* For that combination of covariate j1, we count and print the frequencies in one pass */
                   4383:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4384:        bool=1;
                   4385:        if(j !=0){
                   4386:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4387:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4388:              /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4389:              /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4390:              /* } */
                   4391:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4392:                /* if(Tvaraff[z1] ==-20){ */
                   4393:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4394:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4395:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4396:                /* }else  */
                   4397:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
                   4398:                  /* Tests if this individual iind responded to combination j1 (V4=1 V3=0) */
                   4399:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4400:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4401:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4402:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4403:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4404:                } /* Onlyf fixed */
                   4405:              } /* end z1 */
                   4406:            } /* cptcovn > 0 */
                   4407:          } /* end any */
                   4408:        }/* end j==0 */
                   4409:        if (bool==1){ /* We selected an individual iind satisfying combination j1 or all fixed */
                   4410:          /* for(m=firstpass; m<=lastpass; m++){ */
                   4411:          for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4412:            m=mw[mi][iind];
                   4413:            if(j!=0){
                   4414:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4415:                for (z1=1; z1<=cptcoveff; z1++) {
                   4416:                  if( Fixed[Tmodelind[z1]]==1){
                   4417:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4418:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4419:                                                                                      value is -1, we don't select. It differs from the 
                   4420:                                                                                      constant and age model which counts them. */
                   4421:                      bool=0; /* not selected */
                   4422:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4423:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4424:                      bool=0;
                   4425:                    }
                   4426:                  }
                   4427:                }
                   4428:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4429:            } /* end j==0 */
                   4430:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4431:            if(bool==1){
                   4432:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4433:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4434:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4435:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4436:              if(m >=firstpass && m <=lastpass){
                   4437:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4438:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4439:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4440:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4441:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4442:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4443:                if (m<lastpass) {
                   4444:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4445:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4446:                  if(s[m][iind]==-1)
                   4447:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4448:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4449:                  /* if((int)agev[m][iind] == 55) */
                   4450:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4451:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4452:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4453:                }
1.251     brouard  4454:              } /* end if between passes */  
                   4455:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4456:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4457:                k2cpt++;
                   4458:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4459:              }
1.251     brouard  4460:            }else{
                   4461:              bool=1;
                   4462:            }/* end bool 2 */
                   4463:          } /* end m */
                   4464:        } /* end bool */
                   4465:       } /* end iind = 1 to imx */
                   4466:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4467:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4468:       
                   4469:       
                   4470:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
                   4471:       pstamp(ficresp);
                   4472:       if  (cptcoveff>0 && j!=0){
                   4473:        printf( "\n#********** Variable "); 
                   4474:        fprintf(ficresp, "\n#********** Variable "); 
                   4475:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4476:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4477:        fprintf(ficlog, "\n#********** Variable "); 
                   4478:        for (z1=1; z1<=cptcoveff; z1++){
                   4479:          if(!FixedV[Tvaraff[z1]]){
                   4480:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4481:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4482:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4483:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4484:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4485:          }else{
1.251     brouard  4486:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4487:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4488:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4489:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4490:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4491:          }
                   4492:        }
                   4493:        printf( "**********\n#");
                   4494:        fprintf(ficresp, "**********\n#");
                   4495:        fprintf(ficresphtm, "**********</h3>\n");
                   4496:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4497:        fprintf(ficlog, "**********\n");
                   4498:       }
                   4499:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
                   4500:       for(i=1; i<=nlstate;i++) {
                   4501:        fprintf(ficresp, " Age Prev(%d)  N(%d)  N  ",i,i);
                   4502:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4503:       }
                   4504:       fprintf(ficresp, "\n");
                   4505:       fprintf(ficresphtm, "\n");
                   4506:       
                   4507:       /* Header of frequency table by age */
                   4508:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4509:       fprintf(ficresphtmfr,"<th>Age</th> ");
                   4510:       for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4511:        for(m=-1; m <=nlstate+ndeath; m++){
                   4512:          if(jk!=0 && m!=0)
                   4513:            fprintf(ficresphtmfr,"<th>%d%d</th> ",jk,m);
1.240     brouard  4514:        }
1.226     brouard  4515:       }
1.251     brouard  4516:       fprintf(ficresphtmfr, "\n");
                   4517:     
                   4518:       /* For each age */
                   4519:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4520:        fprintf(ficresphtm,"<tr>");
                   4521:        if(iage==iagemax+1){
                   4522:          fprintf(ficlog,"1");
                   4523:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4524:        }else if(iage==iagemax+2){
                   4525:          fprintf(ficlog,"0");
                   4526:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4527:        }else if(iage==iagemax+3){
                   4528:          fprintf(ficlog,"Total");
                   4529:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4530:        }else{
1.240     brouard  4531:          if(first==1){
1.251     brouard  4532:            first=0;
                   4533:            printf("See log file for details...\n");
                   4534:          }
                   4535:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4536:          fprintf(ficlog,"Age %d", iage);
                   4537:        }
                   4538:        for(jk=1; jk <=nlstate ; jk++){
                   4539:          for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
                   4540:            pp[jk] += freq[jk][m][iage]; 
                   4541:        }
                   4542:        for(jk=1; jk <=nlstate ; jk++){
                   4543:          for(m=-1, pos=0; m <=0 ; m++)
                   4544:            pos += freq[jk][m][iage];
                   4545:          if(pp[jk]>=1.e-10){
                   4546:            if(first==1){
                   4547:              printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4548:            }
                   4549:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4550:          }else{
                   4551:            if(first==1)
                   4552:              printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
                   4553:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
1.240     brouard  4554:          }
                   4555:        }
                   4556:       
1.251     brouard  4557:        for(jk=1; jk <=nlstate ; jk++){ 
                   4558:          /* posprop[jk]=0; */
                   4559:          for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4560:            pp[jk] += freq[jk][m][iage];
                   4561:        }       /* pp[jk] is the total number of transitions starting from state jk and any ending status until this age */
                   4562:       
                   4563:        for(jk=1,pos=0, pospropta=0.; jk <=nlstate ; jk++){
                   4564:          pos += pp[jk]; /* pos is the total number of transitions until this age */
                   4565:          posprop[jk] += prop[jk][iage]; /* prop is the number of transitions from a live state
                   4566:                                            from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4567:          pospropta += prop[jk][iage]; /* prop is the number of transitions from a live state
1.240     brouard  4568:                                          from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4569:        }
1.251     brouard  4570:        for(jk=1; jk <=nlstate ; jk++){
1.240     brouard  4571:          if(pos>=1.e-5){
1.251     brouard  4572:            if(first==1)
                   4573:              printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4574:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4575:          }else{
                   4576:            if(first==1)
                   4577:              printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4578:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4579:          }
                   4580:          if( iage <= iagemax){
                   4581:            if(pos>=1.e-5){
                   4582:              fprintf(ficresp," %d %.5f %.0f %.0f",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4583:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4584:              /*probs[iage][jk][j1]= pp[jk]/pos;*/
                   4585:              /*printf("\niage=%d jk=%d j1=%d %.5f %.0f %.0f %f",iage,jk,j1,pp[jk]/pos, pp[jk],pos,probs[iage][jk][j1]);*/
                   4586:            }
                   4587:            else{
                   4588:              fprintf(ficresp," %d NaNq %.0f %.0f",iage,prop[jk][iage],pospropta);
                   4589:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[jk][iage],pospropta);
                   4590:            }
1.240     brouard  4591:          }
1.251     brouard  4592:          pospropt[jk] +=posprop[jk];
                   4593:        } /* end loop jk */
                   4594:        /* pospropt=0.; */
                   4595:        for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4596:          for(m=-1; m <=nlstate+ndeath; m++){
                   4597:            if(freq[jk][m][iage] !=0 ) { /* minimizing output */
                   4598:              if(first==1){
                   4599:                printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4600:              }
1.253     brouard  4601:              /* printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]); */
1.251     brouard  4602:              fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4603:            }
                   4604:            if(jk!=0 && m!=0)
                   4605:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[jk][m][iage]);
1.240     brouard  4606:          }
1.251     brouard  4607:        } /* end loop jk */
                   4608:        posproptt=0.; 
                   4609:        for(jk=1; jk <=nlstate; jk++){
                   4610:          posproptt += pospropt[jk];
                   4611:        }
                   4612:        fprintf(ficresphtmfr,"</tr>\n ");
                   4613:        if(iage <= iagemax){
                   4614:          fprintf(ficresp,"\n");
                   4615:          fprintf(ficresphtm,"</tr>\n");
1.240     brouard  4616:        }
1.251     brouard  4617:        if(first==1)
                   4618:          printf("Others in log...\n");
                   4619:        fprintf(ficlog,"\n");
                   4620:       } /* end loop age iage */
                   4621:       fprintf(ficresphtm,"<tr><th>Tot</th>");
                   4622:       for(jk=1; jk <=nlstate ; jk++){
                   4623:        if(posproptt < 1.e-5){
                   4624:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[jk],posproptt); 
                   4625:        }else{
                   4626:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[jk]/posproptt,pospropt[jk],posproptt);  
1.240     brouard  4627:        }
1.226     brouard  4628:       }
1.251     brouard  4629:       fprintf(ficresphtm,"</tr>\n");
                   4630:       fprintf(ficresphtm,"</table>\n");
                   4631:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4632:       if(posproptt < 1.e-5){
1.251     brouard  4633:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4634:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4635:        fprintf(ficres,"\n  This combination (%d) is not valid and no result will be produced\n\n",j1);
                   4636:        invalidvarcomb[j1]=1;
1.226     brouard  4637:       }else{
1.251     brouard  4638:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4639:        invalidvarcomb[j1]=0;
1.226     brouard  4640:       }
1.251     brouard  4641:       fprintf(ficresphtmfr,"</table>\n");
                   4642:       fprintf(ficlog,"\n");
                   4643:       if(j!=0){
                   4644:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
                   4645:        for(i=1,jk=1; i <=nlstate; i++){
                   4646:          for(k=1; k <=(nlstate+ndeath); k++){
                   4647:            if (k != i) {
                   4648:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting jk */
1.253     brouard  4649:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4650:                  if(j1==1){ /* All dummy covariates to zero */
                   4651:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4652:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4653:                    printf("%d%d ",i,k);
                   4654:                    fprintf(ficlog,"%d%d ",i,k);
                   4655:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4656:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4657:                    pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4658:                  }
1.253     brouard  4659:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4660:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4661:                    x[iage]= (double)iage;
                   4662:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
                   4663:                    /* printf("i=%d, k=%d, jk=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,jk,j1,jj, iage, y[iage]); */
                   4664:                  }
                   4665:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
                   4666:                  pstart[jk]=b;
                   4667:                  pstart[jk-1]=a;
1.252     brouard  4668:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4669:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4670:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.251     brouard  4671:                  pstart[jk]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4672:                  printf("%d%d ",i,k);
                   4673:                  fprintf(ficlog,"%d%d ",i,k);
1.251     brouard  4674:                  printf("jk=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",jk,i,k,jk,p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
                   4675:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4676:                  ;
                   4677:                }
                   4678:                /* printf("%12.7f )", param[i][jj][k]); */
                   4679:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
                   4680:                jk++; 
                   4681:              } /* end jj */
                   4682:            } /* end k!= i */
                   4683:          } /* end k */
                   4684:        } /* end i, jk */
                   4685:       } /* end j !=0 */
                   4686:     } /* end selected combination of covariate j1 */
                   4687:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4688:       printf("#Freqsummary: Starting values for the constants:\n");
                   4689:       fprintf(ficlog,"\n");
                   4690:       for(i=1,jk=1; i <=nlstate; i++){
                   4691:        for(k=1; k <=(nlstate+ndeath); k++){
                   4692:          if (k != i) {
                   4693:            printf("%d%d ",i,k);
                   4694:            fprintf(ficlog,"%d%d ",i,k);
                   4695:            for(jj=1; jj <=ncovmodel; jj++){
1.253     brouard  4696:              pstart[jk]=p[jk]; /* Setting pstart to p values by default */
                   4697:              if(jj==1){ /* Age has to be done */
                   4698:                pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4699:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4700:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4701:              }
                   4702:              /* printf("%12.7f )", param[i][jj][k]); */
                   4703:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
                   4704:              jk++; 
1.250     brouard  4705:            }
1.251     brouard  4706:            printf("\n");
                   4707:            fprintf(ficlog,"\n");
1.250     brouard  4708:          }
                   4709:        }
                   4710:       }
1.251     brouard  4711:       printf("#Freqsummary\n");
                   4712:       fprintf(ficlog,"\n");
                   4713:       for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4714:        for(m=-1; m <=nlstate+ndeath; m++){
                   4715:          /* param[i]|j][k]= freq[jk][m][iagemax+3] */
1.250     brouard  4716:          printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
                   4717:          fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
1.251     brouard  4718:          /* if(freq[jk][m][iage] !=0 ) { /\* minimizing output *\/ */
                   4719:          /*   printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
                   4720:          /*   fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
                   4721:          /* } */
                   4722:        }
                   4723:       } /* end loop jk */
                   4724:       
                   4725:       printf("\n");
                   4726:       fprintf(ficlog,"\n");
                   4727:     } /* end j=0 */
1.249     brouard  4728:   } /* end j */
1.252     brouard  4729: 
1.253     brouard  4730:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4731:     for(i=1, jk=1; i <=nlstate; i++){
                   4732:       for(j=1; j <=nlstate+ndeath; j++){
                   4733:        if(j!=i){
                   4734:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4735:          printf("%1d%1d",i,j);
                   4736:          fprintf(ficparo,"%1d%1d",i,j);
                   4737:          for(k=1; k<=ncovmodel;k++){
                   4738:            /*    printf(" %lf",param[i][j][k]); */
                   4739:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4740:            p[jk]=pstart[jk];
                   4741:            printf(" %f ",pstart[jk]);
                   4742:            fprintf(ficparo," %f ",pstart[jk]);
                   4743:            jk++;
                   4744:          }
                   4745:          printf("\n");
                   4746:          fprintf(ficparo,"\n");
                   4747:        }
                   4748:       }
                   4749:     }
                   4750:   } /* end mle=-2 */
1.226     brouard  4751:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4752:   
1.226     brouard  4753:   fclose(ficresp);
                   4754:   fclose(ficresphtm);
                   4755:   fclose(ficresphtmfr);
                   4756:   free_vector(meanq,1,nqfveff);
                   4757:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4758:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4759:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4760:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4761:   free_vector(pospropt,1,nlstate);
                   4762:   free_vector(posprop,1,nlstate);
1.251     brouard  4763:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4764:   free_vector(pp,1,nlstate);
                   4765:   /* End of freqsummary */
                   4766: }
1.126     brouard  4767: 
                   4768: /************ Prevalence ********************/
1.227     brouard  4769: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4770: {  
                   4771:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4772:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4773:      We still use firstpass and lastpass as another selection.
                   4774:   */
1.126     brouard  4775:  
1.227     brouard  4776:   int i, m, jk, j1, bool, z1,j, iv;
                   4777:   int mi; /* Effective wave */
                   4778:   int iage;
                   4779:   double agebegin, ageend;
                   4780: 
                   4781:   double **prop;
                   4782:   double posprop; 
                   4783:   double  y2; /* in fractional years */
                   4784:   int iagemin, iagemax;
                   4785:   int first; /** to stop verbosity which is redirected to log file */
                   4786: 
                   4787:   iagemin= (int) agemin;
                   4788:   iagemax= (int) agemax;
                   4789:   /*pp=vector(1,nlstate);*/
1.251     brouard  4790:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  4791:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4792:   j1=0;
1.222     brouard  4793:   
1.227     brouard  4794:   /*j=cptcoveff;*/
                   4795:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4796:   
1.227     brouard  4797:   first=1;
                   4798:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4799:     for (i=1; i<=nlstate; i++)  
1.251     brouard  4800:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  4801:        prop[i][iage]=0.0;
                   4802:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4803:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4804:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4805:     
                   4806:     for (i=1; i<=imx; i++) { /* Each individual */
                   4807:       bool=1;
                   4808:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4809:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4810:        m=mw[mi][i];
                   4811:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4812:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4813:        for (z1=1; z1<=cptcoveff; z1++){
                   4814:          if( Fixed[Tmodelind[z1]]==1){
                   4815:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4816:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4817:              bool=0;
                   4818:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4819:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4820:              bool=0;
                   4821:            }
                   4822:        }
                   4823:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4824:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4825:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4826:          if(m >=firstpass && m <=lastpass){
                   4827:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4828:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4829:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   4830:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  4831:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  4832:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   4833:                exit(1);
                   4834:              }
                   4835:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   4836:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   4837:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   4838:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   4839:              } /* end valid statuses */ 
                   4840:            } /* end selection of dates */
                   4841:          } /* end selection of waves */
                   4842:        } /* end bool */
                   4843:       } /* end wave */
                   4844:     } /* end individual */
                   4845:     for(i=iagemin; i <= iagemax+3; i++){  
                   4846:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   4847:        posprop += prop[jk][i]; 
                   4848:       } 
                   4849:       
                   4850:       for(jk=1; jk <=nlstate ; jk++){      
                   4851:        if( i <=  iagemax){ 
                   4852:          if(posprop>=1.e-5){ 
                   4853:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   4854:          } else{
                   4855:            if(first==1){
                   4856:              first=0;
                   4857:              printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,j1,probs[i][jk][j1]);
                   4858:            }
                   4859:          }
                   4860:        } 
                   4861:       }/* end jk */ 
                   4862:     }/* end i */ 
1.222     brouard  4863:      /*} *//* end i1 */
1.227     brouard  4864:   } /* end j1 */
1.222     brouard  4865:   
1.227     brouard  4866:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   4867:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  4868:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  4869: }  /* End of prevalence */
1.126     brouard  4870: 
                   4871: /************* Waves Concatenation ***************/
                   4872: 
                   4873: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   4874: {
                   4875:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   4876:      Death is a valid wave (if date is known).
                   4877:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   4878:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4879:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  4880:   */
1.126     brouard  4881: 
1.224     brouard  4882:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  4883:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   4884:      double sum=0., jmean=0.;*/
1.224     brouard  4885:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  4886:   int j, k=0,jk, ju, jl;
                   4887:   double sum=0.;
                   4888:   first=0;
1.214     brouard  4889:   firstwo=0;
1.217     brouard  4890:   firsthree=0;
1.218     brouard  4891:   firstfour=0;
1.164     brouard  4892:   jmin=100000;
1.126     brouard  4893:   jmax=-1;
                   4894:   jmean=0.;
1.224     brouard  4895: 
                   4896: /* Treating live states */
1.214     brouard  4897:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  4898:     mi=0;  /* First valid wave */
1.227     brouard  4899:     mli=0; /* Last valid wave */
1.126     brouard  4900:     m=firstpass;
1.214     brouard  4901:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  4902:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   4903:        mli=m-1;/* mw[++mi][i]=m-1; */
                   4904:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   4905:        mw[++mi][i]=m;
                   4906:        mli=m;
1.224     brouard  4907:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   4908:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  4909:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  4910:       }
1.227     brouard  4911:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  4912: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  4913:        break;
1.224     brouard  4914: #else
1.227     brouard  4915:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   4916:          if(firsthree == 0){
                   4917:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4918:            firsthree=1;
                   4919:          }
                   4920:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4921:          mw[++mi][i]=m;
                   4922:          mli=m;
                   4923:        }
                   4924:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   4925:          nbwarn++;
                   4926:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   4927:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4928:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4929:          }
                   4930:          break;
                   4931:        }
                   4932:        break;
1.224     brouard  4933: #endif
1.227     brouard  4934:       }/* End m >= lastpass */
1.126     brouard  4935:     }/* end while */
1.224     brouard  4936: 
1.227     brouard  4937:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  4938:     /* After last pass */
1.224     brouard  4939: /* Treating death states */
1.214     brouard  4940:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  4941:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   4942:       /* } */
1.126     brouard  4943:       mi++;    /* Death is another wave */
                   4944:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  4945:       /* Only death is a correct wave */
1.126     brouard  4946:       mw[mi][i]=m;
1.224     brouard  4947:     }
                   4948: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.227     brouard  4949:     else if ((int) andc[i] != 9999) { /* Status is negative. A death occured after lastpass, we can't take it into account because of potential bias */
1.216     brouard  4950:       /* m++; */
                   4951:       /* mi++; */
                   4952:       /* s[m][i]=nlstate+1;  /\* We are setting the status to the last of non live state *\/ */
                   4953:       /* mw[mi][i]=m; */
1.218     brouard  4954:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  4955:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   4956:          nbwarn++;
                   4957:          if(firstfiv==0){
                   4958:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4959:            firstfiv=1;
                   4960:          }else{
                   4961:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4962:          }
                   4963:        }else{ /* Death occured afer last wave potential bias */
                   4964:          nberr++;
                   4965:          if(firstwo==0){
                   4966:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4967:            firstwo=1;
                   4968:          }
                   4969:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4970:        }
1.218     brouard  4971:       }else{ /* end date of interview is known */
1.227     brouard  4972:        /* death is known but not confirmed by death status at any wave */
                   4973:        if(firstfour==0){
                   4974:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4975:          firstfour=1;
                   4976:        }
                   4977:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  4978:       }
1.224     brouard  4979:     } /* end if date of death is known */
                   4980: #endif
                   4981:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   4982:     /* wav[i]=mw[mi][i]; */
1.126     brouard  4983:     if(mi==0){
                   4984:       nbwarn++;
                   4985:       if(first==0){
1.227     brouard  4986:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   4987:        first=1;
1.126     brouard  4988:       }
                   4989:       if(first==1){
1.227     brouard  4990:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  4991:       }
                   4992:     } /* end mi==0 */
                   4993:   } /* End individuals */
1.214     brouard  4994:   /* wav and mw are no more changed */
1.223     brouard  4995:        
1.214     brouard  4996:   
1.126     brouard  4997:   for(i=1; i<=imx; i++){
                   4998:     for(mi=1; mi<wav[i];mi++){
                   4999:       if (stepm <=0)
1.227     brouard  5000:        dh[mi][i]=1;
1.126     brouard  5001:       else{
1.227     brouard  5002:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death */
                   5003:          if (agedc[i] < 2*AGESUP) {
                   5004:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5005:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5006:            else if(j<0){
                   5007:              nberr++;
                   5008:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5009:              j=1; /* Temporary Dangerous patch */
                   5010:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5011:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5012:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5013:            }
                   5014:            k=k+1;
                   5015:            if (j >= jmax){
                   5016:              jmax=j;
                   5017:              ijmax=i;
                   5018:            }
                   5019:            if (j <= jmin){
                   5020:              jmin=j;
                   5021:              ijmin=i;
                   5022:            }
                   5023:            sum=sum+j;
                   5024:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5025:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5026:          }
                   5027:        }
                   5028:        else{
                   5029:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5030: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5031:                                        
1.227     brouard  5032:          k=k+1;
                   5033:          if (j >= jmax) {
                   5034:            jmax=j;
                   5035:            ijmax=i;
                   5036:          }
                   5037:          else if (j <= jmin){
                   5038:            jmin=j;
                   5039:            ijmin=i;
                   5040:          }
                   5041:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5042:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5043:          if(j<0){
                   5044:            nberr++;
                   5045:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5046:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5047:          }
                   5048:          sum=sum+j;
                   5049:        }
                   5050:        jk= j/stepm;
                   5051:        jl= j -jk*stepm;
                   5052:        ju= j -(jk+1)*stepm;
                   5053:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5054:          if(jl==0){
                   5055:            dh[mi][i]=jk;
                   5056:            bh[mi][i]=0;
                   5057:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5058:                  * to avoid the price of an extra matrix product in likelihood */
                   5059:            dh[mi][i]=jk+1;
                   5060:            bh[mi][i]=ju;
                   5061:          }
                   5062:        }else{
                   5063:          if(jl <= -ju){
                   5064:            dh[mi][i]=jk;
                   5065:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5066:                                 * is higher than the multiple of stepm and negative otherwise.
                   5067:                                 */
                   5068:          }
                   5069:          else{
                   5070:            dh[mi][i]=jk+1;
                   5071:            bh[mi][i]=ju;
                   5072:          }
                   5073:          if(dh[mi][i]==0){
                   5074:            dh[mi][i]=1; /* At least one step */
                   5075:            bh[mi][i]=ju; /* At least one step */
                   5076:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5077:          }
                   5078:        } /* end if mle */
1.126     brouard  5079:       }
                   5080:     } /* end wave */
                   5081:   }
                   5082:   jmean=sum/k;
                   5083:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5084:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5085: }
1.126     brouard  5086: 
                   5087: /*********** Tricode ****************************/
1.220     brouard  5088:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5089:  {
                   5090:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5091:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5092:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5093:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5094:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5095:     */
1.130     brouard  5096: 
1.242     brouard  5097:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5098:    int modmaxcovj=0; /* Modality max of covariates j */
                   5099:    int cptcode=0; /* Modality max of covariates j */
                   5100:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5101: 
                   5102: 
1.242     brouard  5103:    /* cptcoveff=0;  */
                   5104:    /* *cptcov=0; */
1.126     brouard  5105:  
1.242     brouard  5106:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  5107: 
1.242     brouard  5108:    /* Loop on covariates without age and products and no quantitative variable */
                   5109:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5110:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5111:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5112:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5113:        switch(Fixed[k]) {
                   5114:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5115:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5116:           ij=(int)(covar[Tvar[k]][i]);
                   5117:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5118:            * If product of Vn*Vm, still boolean *:
                   5119:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5120:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5121:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5122:              modality of the nth covariate of individual i. */
                   5123:           if (ij > modmaxcovj)
                   5124:             modmaxcovj=ij; 
                   5125:           else if (ij < modmincovj) 
                   5126:             modmincovj=ij; 
                   5127:           if ((ij < -1) && (ij > NCOVMAX)){
                   5128:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5129:             exit(1);
                   5130:           }else
                   5131:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5132:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5133:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5134:           /* getting the maximum value of the modality of the covariate
                   5135:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5136:              female ies 1, then modmaxcovj=1.
                   5137:           */
                   5138:         } /* end for loop on individuals i */
                   5139:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5140:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5141:         cptcode=modmaxcovj;
                   5142:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5143:         /*for (i=0; i<=cptcode; i++) {*/
                   5144:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5145:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5146:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5147:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5148:             if( j != -1){
                   5149:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5150:                                  covariate for which somebody answered excluding 
                   5151:                                  undefined. Usually 2: 0 and 1. */
                   5152:             }
                   5153:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5154:                                     covariate for which somebody answered including 
                   5155:                                     undefined. Usually 3: -1, 0 and 1. */
                   5156:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5157:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5158:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5159:                        
1.242     brouard  5160:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5161:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5162:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5163:         /* modmincovj=3; modmaxcovj = 7; */
                   5164:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5165:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5166:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5167:         /* nbcode[Tvar[j]][ij]=k; */
                   5168:         /* nbcode[Tvar[j]][1]=0; */
                   5169:         /* nbcode[Tvar[j]][2]=1; */
                   5170:         /* nbcode[Tvar[j]][3]=2; */
                   5171:         /* To be continued (not working yet). */
                   5172:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5173:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5174:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5175:             break;
                   5176:           }
                   5177:           ij++;
                   5178:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5179:           cptcode = ij; /* New max modality for covar j */
                   5180:         } /* end of loop on modality i=-1 to 1 or more */
                   5181:         break;
                   5182:        case 1: /* Testing on varying covariate, could be simple and
                   5183:                * should look at waves or product of fixed *
                   5184:                * varying. No time to test -1, assuming 0 and 1 only */
                   5185:         ij=0;
                   5186:         for(i=0; i<=1;i++){
                   5187:           nbcode[Tvar[k]][++ij]=i;
                   5188:         }
                   5189:         break;
                   5190:        default:
                   5191:         break;
                   5192:        } /* end switch */
                   5193:      } /* end dummy test */
                   5194:     
                   5195:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5196:      /*        /\*recode from 0 *\/ */
                   5197:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5198:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5199:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5200:      /*        } */
                   5201:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5202:      /*        if (ij > ncodemax[j]) { */
                   5203:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5204:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5205:      /*          break; */
                   5206:      /*        } */
                   5207:      /*   }  /\* end of loop on modality k *\/ */
                   5208:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5209:   
                   5210:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5211:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5212:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5213:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5214:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5215:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5216:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5217:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5218:   
                   5219:    ij=0;
                   5220:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5221:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5222:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5223:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5224:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5225:        /* If product not in single variable we don't print results */
                   5226:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5227:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5228:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5229:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5230:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5231:        if(Fixed[k]!=0)
                   5232:         anyvaryingduminmodel=1;
                   5233:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5234:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5235:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5236:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5237:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5238:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5239:      } 
                   5240:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5241:    /* ij--; */
                   5242:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5243:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5244:                * because they can be excluded from the model and real
                   5245:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5246:    for(j=ij+1; j<= cptcovt; j++){
                   5247:      Tvaraff[j]=0;
                   5248:      Tmodelind[j]=0;
                   5249:    }
                   5250:    for(j=ntveff+1; j<= cptcovt; j++){
                   5251:      TmodelInvind[j]=0;
                   5252:    }
                   5253:    /* To be sorted */
                   5254:    ;
                   5255:  }
1.126     brouard  5256: 
1.145     brouard  5257: 
1.126     brouard  5258: /*********** Health Expectancies ****************/
                   5259: 
1.235     brouard  5260:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5261: 
                   5262: {
                   5263:   /* Health expectancies, no variances */
1.164     brouard  5264:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5265:   int nhstepma, nstepma; /* Decreasing with age */
                   5266:   double age, agelim, hf;
                   5267:   double ***p3mat;
                   5268:   double eip;
                   5269: 
1.238     brouard  5270:   /* pstamp(ficreseij); */
1.126     brouard  5271:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5272:   fprintf(ficreseij,"# Age");
                   5273:   for(i=1; i<=nlstate;i++){
                   5274:     for(j=1; j<=nlstate;j++){
                   5275:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5276:     }
                   5277:     fprintf(ficreseij," e%1d. ",i);
                   5278:   }
                   5279:   fprintf(ficreseij,"\n");
                   5280: 
                   5281:   
                   5282:   if(estepm < stepm){
                   5283:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5284:   }
                   5285:   else  hstepm=estepm;   
                   5286:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5287:    * This is mainly to measure the difference between two models: for example
                   5288:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5289:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5290:    * progression in between and thus overestimating or underestimating according
                   5291:    * to the curvature of the survival function. If, for the same date, we 
                   5292:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5293:    * to compare the new estimate of Life expectancy with the same linear 
                   5294:    * hypothesis. A more precise result, taking into account a more precise
                   5295:    * curvature will be obtained if estepm is as small as stepm. */
                   5296: 
                   5297:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5298:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5299:      nhstepm is the number of hstepm from age to agelim 
                   5300:      nstepm is the number of stepm from age to agelin. 
                   5301:      Look at hpijx to understand the reason of that which relies in memory size
                   5302:      and note for a fixed period like estepm months */
                   5303:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5304:      survival function given by stepm (the optimization length). Unfortunately it
                   5305:      means that if the survival funtion is printed only each two years of age and if
                   5306:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5307:      results. So we changed our mind and took the option of the best precision.
                   5308:   */
                   5309:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5310: 
                   5311:   agelim=AGESUP;
                   5312:   /* If stepm=6 months */
                   5313:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5314:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5315:     
                   5316: /* nhstepm age range expressed in number of stepm */
                   5317:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5318:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5319:   /* if (stepm >= YEARM) hstepm=1;*/
                   5320:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5321:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5322: 
                   5323:   for (age=bage; age<=fage; age ++){ 
                   5324:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5325:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5326:     /* if (stepm >= YEARM) hstepm=1;*/
                   5327:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5328: 
                   5329:     /* If stepm=6 months */
                   5330:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5331:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5332:     
1.235     brouard  5333:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5334:     
                   5335:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5336:     
                   5337:     printf("%d|",(int)age);fflush(stdout);
                   5338:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5339:     
                   5340:     /* Computing expectancies */
                   5341:     for(i=1; i<=nlstate;i++)
                   5342:       for(j=1; j<=nlstate;j++)
                   5343:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5344:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5345:          
                   5346:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5347: 
                   5348:        }
                   5349: 
                   5350:     fprintf(ficreseij,"%3.0f",age );
                   5351:     for(i=1; i<=nlstate;i++){
                   5352:       eip=0;
                   5353:       for(j=1; j<=nlstate;j++){
                   5354:        eip +=eij[i][j][(int)age];
                   5355:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5356:       }
                   5357:       fprintf(ficreseij,"%9.4f", eip );
                   5358:     }
                   5359:     fprintf(ficreseij,"\n");
                   5360:     
                   5361:   }
                   5362:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5363:   printf("\n");
                   5364:   fprintf(ficlog,"\n");
                   5365:   
                   5366: }
                   5367: 
1.235     brouard  5368:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5369: 
                   5370: {
                   5371:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5372:      to initial status i, ei. .
1.126     brouard  5373:   */
                   5374:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5375:   int nhstepma, nstepma; /* Decreasing with age */
                   5376:   double age, agelim, hf;
                   5377:   double ***p3matp, ***p3matm, ***varhe;
                   5378:   double **dnewm,**doldm;
                   5379:   double *xp, *xm;
                   5380:   double **gp, **gm;
                   5381:   double ***gradg, ***trgradg;
                   5382:   int theta;
                   5383: 
                   5384:   double eip, vip;
                   5385: 
                   5386:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5387:   xp=vector(1,npar);
                   5388:   xm=vector(1,npar);
                   5389:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5390:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5391:   
                   5392:   pstamp(ficresstdeij);
                   5393:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5394:   fprintf(ficresstdeij,"# Age");
                   5395:   for(i=1; i<=nlstate;i++){
                   5396:     for(j=1; j<=nlstate;j++)
                   5397:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5398:     fprintf(ficresstdeij," e%1d. ",i);
                   5399:   }
                   5400:   fprintf(ficresstdeij,"\n");
                   5401: 
                   5402:   pstamp(ficrescveij);
                   5403:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5404:   fprintf(ficrescveij,"# Age");
                   5405:   for(i=1; i<=nlstate;i++)
                   5406:     for(j=1; j<=nlstate;j++){
                   5407:       cptj= (j-1)*nlstate+i;
                   5408:       for(i2=1; i2<=nlstate;i2++)
                   5409:        for(j2=1; j2<=nlstate;j2++){
                   5410:          cptj2= (j2-1)*nlstate+i2;
                   5411:          if(cptj2 <= cptj)
                   5412:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5413:        }
                   5414:     }
                   5415:   fprintf(ficrescveij,"\n");
                   5416:   
                   5417:   if(estepm < stepm){
                   5418:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5419:   }
                   5420:   else  hstepm=estepm;   
                   5421:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5422:    * This is mainly to measure the difference between two models: for example
                   5423:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5424:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5425:    * progression in between and thus overestimating or underestimating according
                   5426:    * to the curvature of the survival function. If, for the same date, we 
                   5427:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5428:    * to compare the new estimate of Life expectancy with the same linear 
                   5429:    * hypothesis. A more precise result, taking into account a more precise
                   5430:    * curvature will be obtained if estepm is as small as stepm. */
                   5431: 
                   5432:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5433:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5434:      nhstepm is the number of hstepm from age to agelim 
                   5435:      nstepm is the number of stepm from age to agelin. 
                   5436:      Look at hpijx to understand the reason of that which relies in memory size
                   5437:      and note for a fixed period like estepm months */
                   5438:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5439:      survival function given by stepm (the optimization length). Unfortunately it
                   5440:      means that if the survival funtion is printed only each two years of age and if
                   5441:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5442:      results. So we changed our mind and took the option of the best precision.
                   5443:   */
                   5444:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5445: 
                   5446:   /* If stepm=6 months */
                   5447:   /* nhstepm age range expressed in number of stepm */
                   5448:   agelim=AGESUP;
                   5449:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5450:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5451:   /* if (stepm >= YEARM) hstepm=1;*/
                   5452:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5453:   
                   5454:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5455:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5456:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5457:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5458:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5459:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5460: 
                   5461:   for (age=bage; age<=fage; age ++){ 
                   5462:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5463:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5464:     /* if (stepm >= YEARM) hstepm=1;*/
                   5465:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5466:                
1.126     brouard  5467:     /* If stepm=6 months */
                   5468:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5469:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5470:     
                   5471:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5472:                
1.126     brouard  5473:     /* Computing  Variances of health expectancies */
                   5474:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5475:        decrease memory allocation */
                   5476:     for(theta=1; theta <=npar; theta++){
                   5477:       for(i=1; i<=npar; i++){ 
1.222     brouard  5478:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5479:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5480:       }
1.235     brouard  5481:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5482:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5483:                        
1.126     brouard  5484:       for(j=1; j<= nlstate; j++){
1.222     brouard  5485:        for(i=1; i<=nlstate; i++){
                   5486:          for(h=0; h<=nhstepm-1; h++){
                   5487:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5488:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5489:          }
                   5490:        }
1.126     brouard  5491:       }
1.218     brouard  5492:                        
1.126     brouard  5493:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5494:        for(h=0; h<=nhstepm-1; h++){
                   5495:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5496:        }
1.126     brouard  5497:     }/* End theta */
                   5498:     
                   5499:     
                   5500:     for(h=0; h<=nhstepm-1; h++)
                   5501:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5502:        for(theta=1; theta <=npar; theta++)
                   5503:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5504:     
1.218     brouard  5505:                
1.222     brouard  5506:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5507:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5508:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5509:                
1.222     brouard  5510:     printf("%d|",(int)age);fflush(stdout);
                   5511:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5512:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5513:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5514:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5515:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5516:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5517:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5518:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5519:       }
                   5520:     }
1.218     brouard  5521:                
1.126     brouard  5522:     /* Computing expectancies */
1.235     brouard  5523:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5524:     for(i=1; i<=nlstate;i++)
                   5525:       for(j=1; j<=nlstate;j++)
1.222     brouard  5526:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5527:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5528:                                        
1.222     brouard  5529:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5530:                                        
1.222     brouard  5531:        }
1.218     brouard  5532:                
1.126     brouard  5533:     fprintf(ficresstdeij,"%3.0f",age );
                   5534:     for(i=1; i<=nlstate;i++){
                   5535:       eip=0.;
                   5536:       vip=0.;
                   5537:       for(j=1; j<=nlstate;j++){
1.222     brouard  5538:        eip += eij[i][j][(int)age];
                   5539:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5540:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5541:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5542:       }
                   5543:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5544:     }
                   5545:     fprintf(ficresstdeij,"\n");
1.218     brouard  5546:                
1.126     brouard  5547:     fprintf(ficrescveij,"%3.0f",age );
                   5548:     for(i=1; i<=nlstate;i++)
                   5549:       for(j=1; j<=nlstate;j++){
1.222     brouard  5550:        cptj= (j-1)*nlstate+i;
                   5551:        for(i2=1; i2<=nlstate;i2++)
                   5552:          for(j2=1; j2<=nlstate;j2++){
                   5553:            cptj2= (j2-1)*nlstate+i2;
                   5554:            if(cptj2 <= cptj)
                   5555:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5556:          }
1.126     brouard  5557:       }
                   5558:     fprintf(ficrescveij,"\n");
1.218     brouard  5559:                
1.126     brouard  5560:   }
                   5561:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5562:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5563:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5564:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5565:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5566:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5567:   printf("\n");
                   5568:   fprintf(ficlog,"\n");
1.218     brouard  5569:        
1.126     brouard  5570:   free_vector(xm,1,npar);
                   5571:   free_vector(xp,1,npar);
                   5572:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5573:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5574:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5575: }
1.218     brouard  5576:  
1.126     brouard  5577: /************ Variance ******************/
1.235     brouard  5578:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5579:  {
                   5580:    /* Variance of health expectancies */
                   5581:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5582:    /* double **newm;*/
                   5583:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5584:   
                   5585:    /* int movingaverage(); */
                   5586:    double **dnewm,**doldm;
                   5587:    double **dnewmp,**doldmp;
                   5588:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5589:    int k;
                   5590:    double *xp;
                   5591:    double **gp, **gm;  /* for var eij */
                   5592:    double ***gradg, ***trgradg; /*for var eij */
                   5593:    double **gradgp, **trgradgp; /* for var p point j */
                   5594:    double *gpp, *gmp; /* for var p point j */
                   5595:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5596:    double ***p3mat;
                   5597:    double age,agelim, hf;
                   5598:    /* double ***mobaverage; */
                   5599:    int theta;
                   5600:    char digit[4];
                   5601:    char digitp[25];
                   5602: 
                   5603:    char fileresprobmorprev[FILENAMELENGTH];
                   5604: 
                   5605:    if(popbased==1){
                   5606:      if(mobilav!=0)
                   5607:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5608:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5609:    }
                   5610:    else 
                   5611:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5612: 
1.218     brouard  5613:    /* if (mobilav!=0) { */
                   5614:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5615:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5616:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5617:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5618:    /*   } */
                   5619:    /* } */
                   5620: 
                   5621:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5622:    sprintf(digit,"%-d",ij);
                   5623:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5624:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5625:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5626:    strcat(fileresprobmorprev,fileresu);
                   5627:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5628:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5629:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5630:    }
                   5631:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5632:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5633:    pstamp(ficresprobmorprev);
                   5634:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5635:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5636:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5637:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5638:    }
                   5639:    for(j=1;j<=cptcoveff;j++) 
                   5640:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5641:    fprintf(ficresprobmorprev,"\n");
                   5642: 
1.218     brouard  5643:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5644:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5645:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5646:      for(i=1; i<=nlstate;i++)
                   5647:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5648:    }  
                   5649:    fprintf(ficresprobmorprev,"\n");
                   5650:   
                   5651:    fprintf(ficgp,"\n# Routine varevsij");
                   5652:    fprintf(ficgp,"\nunset title \n");
                   5653:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5654:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5655:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5656:    /*   } */
                   5657:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5658:    pstamp(ficresvij);
                   5659:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5660:    if(popbased==1)
                   5661:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5662:    else
                   5663:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5664:    fprintf(ficresvij,"# Age");
                   5665:    for(i=1; i<=nlstate;i++)
                   5666:      for(j=1; j<=nlstate;j++)
                   5667:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5668:    fprintf(ficresvij,"\n");
                   5669: 
                   5670:    xp=vector(1,npar);
                   5671:    dnewm=matrix(1,nlstate,1,npar);
                   5672:    doldm=matrix(1,nlstate,1,nlstate);
                   5673:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5674:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5675: 
                   5676:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5677:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5678:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5679:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5680:   
1.218     brouard  5681:    if(estepm < stepm){
                   5682:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5683:    }
                   5684:    else  hstepm=estepm;   
                   5685:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5686:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5687:       nhstepm is the number of hstepm from age to agelim 
                   5688:       nstepm is the number of stepm from age to agelim. 
                   5689:       Look at function hpijx to understand why because of memory size limitations, 
                   5690:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5691:       survival function given by stepm (the optimization length). Unfortunately it
                   5692:       means that if the survival funtion is printed every two years of age and if
                   5693:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5694:       results. So we changed our mind and took the option of the best precision.
                   5695:    */
                   5696:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5697:    agelim = AGESUP;
                   5698:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5699:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5700:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5701:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5702:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5703:      gp=matrix(0,nhstepm,1,nlstate);
                   5704:      gm=matrix(0,nhstepm,1,nlstate);
                   5705:                
                   5706:                
                   5707:      for(theta=1; theta <=npar; theta++){
                   5708:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5709:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5710:        }
                   5711:                        
1.242     brouard  5712:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5713:                        
                   5714:        if (popbased==1) {
                   5715:         if(mobilav ==0){
                   5716:           for(i=1; i<=nlstate;i++)
                   5717:             prlim[i][i]=probs[(int)age][i][ij];
                   5718:         }else{ /* mobilav */ 
                   5719:           for(i=1; i<=nlstate;i++)
                   5720:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5721:         }
                   5722:        }
                   5723:                        
1.235     brouard  5724:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5725:        for(j=1; j<= nlstate; j++){
                   5726:         for(h=0; h<=nhstepm; h++){
                   5727:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5728:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5729:         }
                   5730:        }
                   5731:        /* Next for computing probability of death (h=1 means
                   5732:          computed over hstepm matrices product = hstepm*stepm months) 
                   5733:          as a weighted average of prlim.
                   5734:        */
                   5735:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5736:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5737:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5738:        }    
                   5739:        /* end probability of death */
                   5740:                        
                   5741:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5742:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5743:                        
1.242     brouard  5744:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5745:                        
                   5746:        if (popbased==1) {
                   5747:         if(mobilav ==0){
                   5748:           for(i=1; i<=nlstate;i++)
                   5749:             prlim[i][i]=probs[(int)age][i][ij];
                   5750:         }else{ /* mobilav */ 
                   5751:           for(i=1; i<=nlstate;i++)
                   5752:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5753:         }
                   5754:        }
                   5755:                        
1.235     brouard  5756:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5757:                        
                   5758:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5759:         for(h=0; h<=nhstepm; h++){
                   5760:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5761:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5762:         }
                   5763:        }
                   5764:        /* This for computing probability of death (h=1 means
                   5765:          computed over hstepm matrices product = hstepm*stepm months) 
                   5766:          as a weighted average of prlim.
                   5767:        */
                   5768:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5769:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5770:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5771:        }    
                   5772:        /* end probability of death */
                   5773:                        
                   5774:        for(j=1; j<= nlstate; j++) /* vareij */
                   5775:         for(h=0; h<=nhstepm; h++){
                   5776:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5777:         }
                   5778:                        
                   5779:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5780:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5781:        }
                   5782:                        
                   5783:      } /* End theta */
                   5784:                
                   5785:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5786:                
                   5787:      for(h=0; h<=nhstepm; h++) /* veij */
                   5788:        for(j=1; j<=nlstate;j++)
                   5789:         for(theta=1; theta <=npar; theta++)
                   5790:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5791:                
                   5792:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5793:        for(theta=1; theta <=npar; theta++)
                   5794:         trgradgp[j][theta]=gradgp[theta][j];
                   5795:                
                   5796:                
                   5797:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5798:      for(i=1;i<=nlstate;i++)
                   5799:        for(j=1;j<=nlstate;j++)
                   5800:         vareij[i][j][(int)age] =0.;
                   5801:                
                   5802:      for(h=0;h<=nhstepm;h++){
                   5803:        for(k=0;k<=nhstepm;k++){
                   5804:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5805:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5806:         for(i=1;i<=nlstate;i++)
                   5807:           for(j=1;j<=nlstate;j++)
                   5808:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5809:        }
                   5810:      }
                   5811:                
                   5812:      /* pptj */
                   5813:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5814:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5815:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5816:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5817:         varppt[j][i]=doldmp[j][i];
                   5818:      /* end ppptj */
                   5819:      /*  x centered again */
                   5820:                
1.242     brouard  5821:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5822:                
                   5823:      if (popbased==1) {
                   5824:        if(mobilav ==0){
                   5825:         for(i=1; i<=nlstate;i++)
                   5826:           prlim[i][i]=probs[(int)age][i][ij];
                   5827:        }else{ /* mobilav */ 
                   5828:         for(i=1; i<=nlstate;i++)
                   5829:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   5830:        }
                   5831:      }
                   5832:                
                   5833:      /* This for computing probability of death (h=1 means
                   5834:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   5835:        as a weighted average of prlim.
                   5836:      */
1.235     brouard  5837:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  5838:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5839:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   5840:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   5841:      }    
                   5842:      /* end probability of death */
                   5843:                
                   5844:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   5845:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5846:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   5847:        for(i=1; i<=nlstate;i++){
                   5848:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   5849:        }
                   5850:      } 
                   5851:      fprintf(ficresprobmorprev,"\n");
                   5852:                
                   5853:      fprintf(ficresvij,"%.0f ",age );
                   5854:      for(i=1; i<=nlstate;i++)
                   5855:        for(j=1; j<=nlstate;j++){
                   5856:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   5857:        }
                   5858:      fprintf(ficresvij,"\n");
                   5859:      free_matrix(gp,0,nhstepm,1,nlstate);
                   5860:      free_matrix(gm,0,nhstepm,1,nlstate);
                   5861:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   5862:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   5863:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5864:    } /* End age */
                   5865:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   5866:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   5867:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   5868:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   5869:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   5870:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   5871:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   5872:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   5873:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5874:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   5875:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5876:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5877:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   5878:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   5879:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   5880:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   5881:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5882:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  5883:     */
1.218     brouard  5884:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   5885:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  5886: 
1.218     brouard  5887:    free_vector(xp,1,npar);
                   5888:    free_matrix(doldm,1,nlstate,1,nlstate);
                   5889:    free_matrix(dnewm,1,nlstate,1,npar);
                   5890:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5891:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   5892:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5893:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5894:    fclose(ficresprobmorprev);
                   5895:    fflush(ficgp);
                   5896:    fflush(fichtm); 
                   5897:  }  /* end varevsij */
1.126     brouard  5898: 
                   5899: /************ Variance of prevlim ******************/
1.235     brouard  5900:  void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  5901: {
1.205     brouard  5902:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  5903:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  5904: 
1.126     brouard  5905:   double **dnewm,**doldm;
                   5906:   int i, j, nhstepm, hstepm;
                   5907:   double *xp;
                   5908:   double *gp, *gm;
                   5909:   double **gradg, **trgradg;
1.208     brouard  5910:   double **mgm, **mgp;
1.126     brouard  5911:   double age,agelim;
                   5912:   int theta;
                   5913:   
                   5914:   pstamp(ficresvpl);
                   5915:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  5916:   fprintf(ficresvpl,"# Age ");
                   5917:   if(nresult >=1)
                   5918:     fprintf(ficresvpl," Result# ");
1.126     brouard  5919:   for(i=1; i<=nlstate;i++)
                   5920:       fprintf(ficresvpl," %1d-%1d",i,i);
                   5921:   fprintf(ficresvpl,"\n");
                   5922: 
                   5923:   xp=vector(1,npar);
                   5924:   dnewm=matrix(1,nlstate,1,npar);
                   5925:   doldm=matrix(1,nlstate,1,nlstate);
                   5926:   
                   5927:   hstepm=1*YEARM; /* Every year of age */
                   5928:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   5929:   agelim = AGESUP;
                   5930:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5931:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5932:     if (stepm >= YEARM) hstepm=1;
                   5933:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   5934:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  5935:     mgp=matrix(1,npar,1,nlstate);
                   5936:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  5937:     gp=vector(1,nlstate);
                   5938:     gm=vector(1,nlstate);
                   5939: 
                   5940:     for(theta=1; theta <=npar; theta++){
                   5941:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   5942:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5943:       }
1.209     brouard  5944:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5945:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5946:       else
1.235     brouard  5947:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5948:       for(i=1;i<=nlstate;i++){
1.126     brouard  5949:        gp[i] = prlim[i][i];
1.208     brouard  5950:        mgp[theta][i] = prlim[i][i];
                   5951:       }
1.126     brouard  5952:       for(i=1; i<=npar; i++) /* Computes gradient */
                   5953:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  5954:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5955:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5956:       else
1.235     brouard  5957:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5958:       for(i=1;i<=nlstate;i++){
1.126     brouard  5959:        gm[i] = prlim[i][i];
1.208     brouard  5960:        mgm[theta][i] = prlim[i][i];
                   5961:       }
1.126     brouard  5962:       for(i=1;i<=nlstate;i++)
                   5963:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  5964:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  5965:     } /* End theta */
                   5966: 
                   5967:     trgradg =matrix(1,nlstate,1,npar);
                   5968: 
                   5969:     for(j=1; j<=nlstate;j++)
                   5970:       for(theta=1; theta <=npar; theta++)
                   5971:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  5972:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5973:     /*   printf("\nmgm mgp %d ",(int)age); */
                   5974:     /*   for(j=1; j<=nlstate;j++){ */
                   5975:     /*         printf(" %d ",j); */
                   5976:     /*         for(theta=1; theta <=npar; theta++) */
                   5977:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   5978:     /*         printf("\n "); */
                   5979:     /*   } */
                   5980:     /* } */
                   5981:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5982:     /*   printf("\n gradg %d ",(int)age); */
                   5983:     /*   for(j=1; j<=nlstate;j++){ */
                   5984:     /*         printf("%d ",j); */
                   5985:     /*         for(theta=1; theta <=npar; theta++) */
                   5986:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   5987:     /*         printf("\n "); */
                   5988:     /*   } */
                   5989:     /* } */
1.126     brouard  5990: 
                   5991:     for(i=1;i<=nlstate;i++)
                   5992:       varpl[i][(int)age] =0.;
1.209     brouard  5993:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.205     brouard  5994:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   5995:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
                   5996:     }else{
1.126     brouard  5997:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   5998:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  5999:     }
1.126     brouard  6000:     for(i=1;i<=nlstate;i++)
                   6001:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6002: 
                   6003:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6004:     if(nresult >=1)
                   6005:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6006:     for(i=1; i<=nlstate;i++)
                   6007:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6008:     fprintf(ficresvpl,"\n");
                   6009:     free_vector(gp,1,nlstate);
                   6010:     free_vector(gm,1,nlstate);
1.208     brouard  6011:     free_matrix(mgm,1,npar,1,nlstate);
                   6012:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6013:     free_matrix(gradg,1,npar,1,nlstate);
                   6014:     free_matrix(trgradg,1,nlstate,1,npar);
                   6015:   } /* End age */
                   6016: 
                   6017:   free_vector(xp,1,npar);
                   6018:   free_matrix(doldm,1,nlstate,1,npar);
                   6019:   free_matrix(dnewm,1,nlstate,1,nlstate);
                   6020: 
                   6021: }
                   6022: 
                   6023: /************ Variance of one-step probabilities  ******************/
                   6024: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6025:  {
                   6026:    int i, j=0,  k1, l1, tj;
                   6027:    int k2, l2, j1,  z1;
                   6028:    int k=0, l;
                   6029:    int first=1, first1, first2;
                   6030:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6031:    double **dnewm,**doldm;
                   6032:    double *xp;
                   6033:    double *gp, *gm;
                   6034:    double **gradg, **trgradg;
                   6035:    double **mu;
                   6036:    double age, cov[NCOVMAX+1];
                   6037:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6038:    int theta;
                   6039:    char fileresprob[FILENAMELENGTH];
                   6040:    char fileresprobcov[FILENAMELENGTH];
                   6041:    char fileresprobcor[FILENAMELENGTH];
                   6042:    double ***varpij;
                   6043: 
                   6044:    strcpy(fileresprob,"PROB_"); 
                   6045:    strcat(fileresprob,fileres);
                   6046:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6047:      printf("Problem with resultfile: %s\n", fileresprob);
                   6048:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6049:    }
                   6050:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6051:    strcat(fileresprobcov,fileresu);
                   6052:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6053:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6054:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6055:    }
                   6056:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6057:    strcat(fileresprobcor,fileresu);
                   6058:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6059:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6060:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6061:    }
                   6062:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6063:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6064:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6065:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6066:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6067:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6068:    pstamp(ficresprob);
                   6069:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6070:    fprintf(ficresprob,"# Age");
                   6071:    pstamp(ficresprobcov);
                   6072:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6073:    fprintf(ficresprobcov,"# Age");
                   6074:    pstamp(ficresprobcor);
                   6075:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6076:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6077: 
                   6078: 
1.222     brouard  6079:    for(i=1; i<=nlstate;i++)
                   6080:      for(j=1; j<=(nlstate+ndeath);j++){
                   6081:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6082:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6083:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6084:      }  
                   6085:    /* fprintf(ficresprob,"\n");
                   6086:       fprintf(ficresprobcov,"\n");
                   6087:       fprintf(ficresprobcor,"\n");
                   6088:    */
                   6089:    xp=vector(1,npar);
                   6090:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6091:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6092:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6093:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6094:    first=1;
                   6095:    fprintf(ficgp,"\n# Routine varprob");
                   6096:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6097:    fprintf(fichtm,"\n");
                   6098: 
                   6099:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.</li>\n",optionfilehtmcov);
                   6100:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6101:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6102: and drawn. It helps understanding how is the covariance between two incidences.\
                   6103:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6104:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6105: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6106: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6107: standard deviations wide on each axis. <br>\
                   6108:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6109:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6110: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6111: 
1.222     brouard  6112:    cov[1]=1;
                   6113:    /* tj=cptcoveff; */
1.225     brouard  6114:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6115:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6116:    j1=0;
1.224     brouard  6117:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6118:      if  (cptcovn>0) {
                   6119:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6120:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6121:        fprintf(ficresprob, "**********\n#\n");
                   6122:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6123:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6124:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6125:                        
1.222     brouard  6126:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6127:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6128:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6129:                        
                   6130:                        
1.222     brouard  6131:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6132:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6133:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6134:                        
1.222     brouard  6135:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6136:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6137:        fprintf(ficresprobcor, "**********\n#");    
                   6138:        if(invalidvarcomb[j1]){
                   6139:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6140:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6141:         continue;
                   6142:        }
                   6143:      }
                   6144:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6145:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6146:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6147:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6148:      for (age=bage; age<=fage; age ++){ 
                   6149:        cov[2]=age;
                   6150:        if(nagesqr==1)
                   6151:         cov[3]= age*age;
                   6152:        for (k=1; k<=cptcovn;k++) {
                   6153:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6154:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6155:                                                                    * 1  1 1 1 1
                   6156:                                                                    * 2  2 1 1 1
                   6157:                                                                    * 3  1 2 1 1
                   6158:                                                                    */
                   6159:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6160:        }
                   6161:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6162:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6163:        for (k=1; k<=cptcovprod;k++)
                   6164:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6165:                        
                   6166:                        
1.222     brouard  6167:        for(theta=1; theta <=npar; theta++){
                   6168:         for(i=1; i<=npar; i++)
                   6169:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6170:                                
1.222     brouard  6171:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6172:                                
1.222     brouard  6173:         k=0;
                   6174:         for(i=1; i<= (nlstate); i++){
                   6175:           for(j=1; j<=(nlstate+ndeath);j++){
                   6176:             k=k+1;
                   6177:             gp[k]=pmmij[i][j];
                   6178:           }
                   6179:         }
1.220     brouard  6180:                                
1.222     brouard  6181:         for(i=1; i<=npar; i++)
                   6182:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6183:                                
1.222     brouard  6184:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6185:         k=0;
                   6186:         for(i=1; i<=(nlstate); i++){
                   6187:           for(j=1; j<=(nlstate+ndeath);j++){
                   6188:             k=k+1;
                   6189:             gm[k]=pmmij[i][j];
                   6190:           }
                   6191:         }
1.220     brouard  6192:                                
1.222     brouard  6193:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6194:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6195:        }
1.126     brouard  6196: 
1.222     brouard  6197:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6198:         for(theta=1; theta <=npar; theta++)
                   6199:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6200:                        
1.222     brouard  6201:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6202:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6203:                        
1.222     brouard  6204:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6205:                        
1.222     brouard  6206:        k=0;
                   6207:        for(i=1; i<=(nlstate); i++){
                   6208:         for(j=1; j<=(nlstate+ndeath);j++){
                   6209:           k=k+1;
                   6210:           mu[k][(int) age]=pmmij[i][j];
                   6211:         }
                   6212:        }
                   6213:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6214:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6215:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6216:                        
1.222     brouard  6217:        /*printf("\n%d ",(int)age);
                   6218:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6219:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6220:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6221:         }*/
1.220     brouard  6222:                        
1.222     brouard  6223:        fprintf(ficresprob,"\n%d ",(int)age);
                   6224:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6225:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6226:                        
1.222     brouard  6227:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6228:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6229:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6230:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6231:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6232:        }
                   6233:        i=0;
                   6234:        for (k=1; k<=(nlstate);k++){
                   6235:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6236:           i++;
                   6237:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6238:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6239:           for (j=1; j<=i;j++){
                   6240:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6241:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6242:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6243:           }
                   6244:         }
                   6245:        }/* end of loop for state */
                   6246:      } /* end of loop for age */
                   6247:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6248:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6249:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6250:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6251:     
                   6252:      /* Confidence intervalle of pij  */
                   6253:      /*
                   6254:        fprintf(ficgp,"\nunset parametric;unset label");
                   6255:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6256:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6257:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6258:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6259:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6260:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6261:      */
                   6262:                
                   6263:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6264:      first1=1;first2=2;
                   6265:      for (k2=1; k2<=(nlstate);k2++){
                   6266:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6267:         if(l2==k2) continue;
                   6268:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6269:         for (k1=1; k1<=(nlstate);k1++){
                   6270:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6271:             if(l1==k1) continue;
                   6272:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6273:             if(i<=j) continue;
                   6274:             for (age=bage; age<=fage; age ++){ 
                   6275:               if ((int)age %5==0){
                   6276:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6277:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6278:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6279:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6280:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6281:                 c12=cv12/sqrt(v1*v2);
                   6282:                 /* Computing eigen value of matrix of covariance */
                   6283:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6284:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6285:                 if ((lc2 <0) || (lc1 <0) ){
                   6286:                   if(first2==1){
                   6287:                     first1=0;
                   6288:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6289:                   }
                   6290:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6291:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6292:                   /* lc2=fabs(lc2); */
                   6293:                 }
1.220     brouard  6294:                                                                
1.222     brouard  6295:                 /* Eigen vectors */
                   6296:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   6297:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6298:                 v21=(lc1-v1)/cv12*v11;
                   6299:                 v12=-v21;
                   6300:                 v22=v11;
                   6301:                 tnalp=v21/v11;
                   6302:                 if(first1==1){
                   6303:                   first1=0;
                   6304:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6305:                 }
                   6306:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6307:                 /*printf(fignu*/
                   6308:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6309:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6310:                 if(first==1){
                   6311:                   first=0;
                   6312:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6313:                   fprintf(ficgp,"\nset parametric;unset label");
                   6314:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6315:                   fprintf(ficgp,"\nset ter svg size 640, 480");
                   6316:                   fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6317:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6318: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6319:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6320:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6321:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6322:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6323:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6324:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6325:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6326:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
                   6327:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                                                         \
                   6328:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6329:                 }else{
                   6330:                   first=0;
                   6331:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6332:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6333:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6334:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
                   6335:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                 \
                   6336:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6337:                 }/* if first */
                   6338:               } /* age mod 5 */
                   6339:             } /* end loop age */
                   6340:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6341:             first=1;
                   6342:           } /*l12 */
                   6343:         } /* k12 */
                   6344:        } /*l1 */
                   6345:      }/* k1 */
                   6346:    }  /* loop on combination of covariates j1 */
                   6347:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6348:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6349:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6350:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6351:    free_vector(xp,1,npar);
                   6352:    fclose(ficresprob);
                   6353:    fclose(ficresprobcov);
                   6354:    fclose(ficresprobcor);
                   6355:    fflush(ficgp);
                   6356:    fflush(fichtmcov);
                   6357:  }
1.126     brouard  6358: 
                   6359: 
                   6360: /******************* Printing html file ***********/
1.201     brouard  6361: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6362:                  int lastpass, int stepm, int weightopt, char model[],\
                   6363:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.217     brouard  6364:                  int popforecast, int prevfcast, int backcast, int estepm , \
1.213     brouard  6365:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   6366:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.237     brouard  6367:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6368: 
                   6369:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6370:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6371: </ul>");
1.237     brouard  6372:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6373: </ul>", model);
1.214     brouard  6374:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6375:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6376:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6377:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6378:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6379:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6380:    fprintf(fichtm,"\
                   6381:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6382:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6383:    fprintf(fichtm,"\
1.217     brouard  6384:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6385:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6386:    fprintf(fichtm,"\
1.126     brouard  6387:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6388:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6389:    fprintf(fichtm,"\
1.217     brouard  6390:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6391:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6392:    fprintf(fichtm,"\
1.211     brouard  6393:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6394:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6395:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6396:    if(prevfcast==1){
                   6397:      fprintf(fichtm,"\
                   6398:  - Prevalence projections by age and states:                           \
1.201     brouard  6399:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6400:    }
1.126     brouard  6401: 
1.222     brouard  6402:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
1.126     brouard  6403: 
1.225     brouard  6404:    m=pow(2,cptcoveff);
1.222     brouard  6405:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6406: 
1.222     brouard  6407:    jj1=0;
1.237     brouard  6408: 
                   6409:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6410:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6411:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6412:        continue;
1.220     brouard  6413: 
1.222     brouard  6414:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6415:      jj1++;
                   6416:      if (cptcovn > 0) {
                   6417:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6418:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6419:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6420:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6421:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6422:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6423:        }
1.237     brouard  6424:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6425:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6426:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6427:       }
                   6428:        
1.230     brouard  6429:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6430:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6431:        if(invalidvarcomb[k1]){
                   6432:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6433:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6434:         continue;
                   6435:        }
                   6436:      }
                   6437:      /* aij, bij */
1.241     brouard  6438:      fprintf(fichtm,"<br>- Logit model (yours is: 1+age+%s), for example: logit(pij)=log(pij/pii)= aij+ bij age + V1 age + etc. as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
                   6439: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6440:      /* Pij */
1.241     brouard  6441:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6442: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6443:      /* Quasi-incidences */
                   6444:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6445:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6446:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6447: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6448: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6449:      /* Survival functions (period) in state j */
                   6450:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6451:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6452: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6453:      }
                   6454:      /* State specific survival functions (period) */
                   6455:      for(cpt=1; cpt<=nlstate;cpt++){
                   6456:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6457:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.241     brouard  6458:  <a href=\"%s_%d-%d-%d.svg\">%s_%d%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6459:      }
                   6460:      /* Period (stable) prevalence in each health state */
                   6461:      for(cpt=1; cpt<=nlstate;cpt++){
1.255   ! brouard  6462:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d some years earlier, knowing that we will be in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6463: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6464:      }
                   6465:      if(backcast==1){
                   6466:        /* Period (stable) back prevalence in each health state */
                   6467:        for(cpt=1; cpt<=nlstate;cpt++){
1.255   ! brouard  6468:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability to be in state %d at a younger age, knowing that we will be in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6469: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6470:        }
1.217     brouard  6471:      }
1.222     brouard  6472:      if(prevfcast==1){
                   6473:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6474:        for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6475:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f) up to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6476: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6477:        }
                   6478:      }
1.220     brouard  6479:         
1.222     brouard  6480:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6481:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6482: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6483:      }
                   6484:      /* } /\* end i1 *\/ */
                   6485:    }/* End k1 */
                   6486:    fprintf(fichtm,"</ul>");
1.126     brouard  6487: 
1.222     brouard  6488:    fprintf(fichtm,"\
1.126     brouard  6489: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6490:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6491:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6492: But because parameters are usually highly correlated (a higher incidence of disability \
                   6493: and a higher incidence of recovery can give very close observed transition) it might \
                   6494: be very useful to look not only at linear confidence intervals estimated from the \
                   6495: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6496: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6497: covariance matrix of the one-step probabilities. \
                   6498: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6499: 
1.222     brouard  6500:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6501:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6502:    fprintf(fichtm,"\
1.126     brouard  6503:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6504:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6505: 
1.222     brouard  6506:    fprintf(fichtm,"\
1.126     brouard  6507:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6508:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6509:    fprintf(fichtm,"\
1.126     brouard  6510:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6511:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6512:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6513:    fprintf(fichtm,"\
1.126     brouard  6514:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6515:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6516:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6517:    fprintf(fichtm,"\
1.128     brouard  6518:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6519:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6520:    fprintf(fichtm,"\
1.128     brouard  6521:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6522:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6523:    fprintf(fichtm,"\
1.126     brouard  6524:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6525:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6526: 
                   6527: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6528: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6529: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6530: /*     <br>",fileres,fileres,fileres,fileres); */
                   6531: /*  else  */
                   6532: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6533:    fflush(fichtm);
                   6534:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6535: 
1.225     brouard  6536:    m=pow(2,cptcoveff);
1.222     brouard  6537:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6538: 
1.222     brouard  6539:    jj1=0;
1.237     brouard  6540: 
1.241     brouard  6541:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6542:    for(k1=1; k1<=m;k1++){
1.253     brouard  6543:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6544:        continue;
1.222     brouard  6545:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6546:      jj1++;
1.126     brouard  6547:      if (cptcovn > 0) {
                   6548:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6549:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6550:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6551:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6552:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6553:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6554:       }
                   6555: 
1.126     brouard  6556:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6557: 
1.222     brouard  6558:        if(invalidvarcomb[k1]){
                   6559:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6560:         continue;
                   6561:        }
1.126     brouard  6562:      }
                   6563:      for(cpt=1; cpt<=nlstate;cpt++) {
1.218     brouard  6564:        fprintf(fichtm,"\n<br>- Observed (cross-sectional) and period (incidence based) \
1.241     brouard  6565: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
                   6566: <img src=\"%s_%d-%d-%d.svg\">",cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  6567:      }
                   6568:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6569: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6570: true period expectancies (those weighted with period prevalences are also\
                   6571:  drawn in addition to the population based expectancies computed using\
1.241     brouard  6572:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   6573: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  6574:      /* } /\* end i1 *\/ */
                   6575:    }/* End k1 */
1.241     brouard  6576:   }/* End nres */
1.222     brouard  6577:    fprintf(fichtm,"</ul>");
                   6578:    fflush(fichtm);
1.126     brouard  6579: }
                   6580: 
                   6581: /******************* Gnuplot file **************/
1.223     brouard  6582: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[]){
1.126     brouard  6583: 
                   6584:   char dirfileres[132],optfileres[132];
1.223     brouard  6585:   char gplotcondition[132];
1.237     brouard  6586:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6587:   int lv=0, vlv=0, kl=0;
1.130     brouard  6588:   int ng=0;
1.201     brouard  6589:   int vpopbased;
1.223     brouard  6590:   int ioffset; /* variable offset for columns */
1.235     brouard  6591:   int nres=0; /* Index of resultline */
1.219     brouard  6592: 
1.126     brouard  6593: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6594: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6595: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6596: /*   } */
                   6597: 
                   6598:   /*#ifdef windows */
                   6599:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6600:   /*#endif */
1.225     brouard  6601:   m=pow(2,cptcoveff);
1.126     brouard  6602: 
1.202     brouard  6603:   /* Contribution to likelihood */
                   6604:   /* Plot the probability implied in the likelihood */
1.223     brouard  6605:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6606:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6607:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6608:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6609: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6610:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6611: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6612:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6613:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6614:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6615:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6616:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6617:   for (i=1; i<= nlstate ; i ++) {
                   6618:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6619:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6620:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6621:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6622:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6623:     }
                   6624:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6625:   }
                   6626:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6627:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6628:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6629:   fprintf(ficgp,"\nset out;unset log\n");
                   6630:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6631: 
1.126     brouard  6632:   strcpy(dirfileres,optionfilefiname);
                   6633:   strcpy(optfileres,"vpl");
1.223     brouard  6634:   /* 1eme*/
1.238     brouard  6635:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   6636:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  6637:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  6638:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  6639:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6640:          continue;
                   6641:        /* We are interested in selected combination by the resultline */
1.246     brouard  6642:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  6643:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
                   6644:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6645:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   6646:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6647:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6648:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6649:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   6650:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  6651:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  6652:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6653:        }
                   6654:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  6655:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  6656:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6657:        }       
1.246     brouard  6658:        /* printf("\n#\n"); */
1.238     brouard  6659:        fprintf(ficgp,"\n#\n");
                   6660:        if(invalidvarcomb[k1]){
                   6661:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6662:          continue;
                   6663:        }
1.235     brouard  6664:       
1.241     brouard  6665:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   6666:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
                   6667:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres);
1.235     brouard  6668:       
1.238     brouard  6669:        for (i=1; i<= nlstate ; i ++) {
                   6670:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6671:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   6672:        }
1.242     brouard  6673:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres);
1.238     brouard  6674:        for (i=1; i<= nlstate ; i ++) {
                   6675:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6676:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6677:        } 
1.242     brouard  6678:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); 
1.238     brouard  6679:        for (i=1; i<= nlstate ; i ++) {
                   6680:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6681:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6682:        }  
                   6683:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1));
                   6684:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   6685:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  6686:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  6687:          if(cptcoveff ==0){
1.245     brouard  6688:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  6689:          }else{
                   6690:            kl=0;
                   6691:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   6692:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6693:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6694:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6695:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6696:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  6697:              kl++;
1.238     brouard  6698:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6699:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6700:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6701:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6702:              if(k==cptcoveff){
1.245     brouard  6703:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  6704:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  6705:              }else{
                   6706:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   6707:                kl++;
                   6708:              }
                   6709:            } /* end covariate */
                   6710:          } /* end if no covariate */
                   6711:        } /* end if backcast */
                   6712:        fprintf(ficgp,"\nset out \n");
                   6713:       } /* nres */
1.201     brouard  6714:     } /* k1 */
                   6715:   } /* cpt */
1.235     brouard  6716: 
                   6717:   
1.126     brouard  6718:   /*2 eme*/
1.238     brouard  6719:   for (k1=1; k1<= m ; k1 ++){  
                   6720:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6721:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6722:        continue;
                   6723:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
                   6724:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  6725:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6726:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6727:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6728:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6729:        vlv= nbcode[Tvaraff[k]][lv];
                   6730:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6731:       }
1.237     brouard  6732:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  6733:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  6734:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  6735:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  6736:       }
1.211     brouard  6737:       fprintf(ficgp,"\n#\n");
1.223     brouard  6738:       if(invalidvarcomb[k1]){
                   6739:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6740:        continue;
                   6741:       }
1.219     brouard  6742:                        
1.241     brouard  6743:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  6744:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
                   6745:        if(vpopbased==0)
                   6746:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
                   6747:        else
                   6748:          fprintf(ficgp,"\nreplot ");
                   6749:        for (i=1; i<= nlstate+1 ; i ++) {
                   6750:          k=2*i;
                   6751:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1, vpopbased);
                   6752:          for (j=1; j<= nlstate+1 ; j ++) {
                   6753:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6754:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6755:          }   
                   6756:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   6757:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
                   6758:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6759:          for (j=1; j<= nlstate+1 ; j ++) {
                   6760:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6761:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6762:          }   
                   6763:          fprintf(ficgp,"\" t\"\" w l lt 0,");
                   6764:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6765:          for (j=1; j<= nlstate+1 ; j ++) {
                   6766:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6767:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6768:          }   
                   6769:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   6770:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   6771:        } /* state */
                   6772:       } /* vpopbased */
1.244     brouard  6773:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  6774:     } /* end nres */
                   6775:   } /* k1 end 2 eme*/
                   6776:        
                   6777:        
                   6778:   /*3eme*/
                   6779:   for (k1=1; k1<= m ; k1 ++){
                   6780:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6781:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6782:        continue;
                   6783: 
                   6784:       for (cpt=1; cpt<= nlstate ; cpt ++) {
                   6785:        fprintf(ficgp,"\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
                   6786:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6787:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6788:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6789:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6790:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6791:          vlv= nbcode[Tvaraff[k]][lv];
                   6792:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6793:        }
                   6794:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6795:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6796:        }       
                   6797:        fprintf(ficgp,"\n#\n");
                   6798:        if(invalidvarcomb[k1]){
                   6799:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6800:          continue;
                   6801:        }
                   6802:                        
                   6803:        /*       k=2+nlstate*(2*cpt-2); */
                   6804:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  6805:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.238     brouard  6806:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.201     brouard  6807: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),k1-1,k1-1,k,cpt);
1.238     brouard  6808:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6809:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6810:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   6811:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6812:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6813:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  6814:                                
1.238     brouard  6815:        */
                   6816:        for (i=1; i< nlstate ; i ++) {
                   6817:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+i,cpt,i+1);
                   6818:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  6819:                                
1.238     brouard  6820:        } 
                   6821:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+nlstate,cpt);
                   6822:       }
                   6823:     } /* end nres */
                   6824:   } /* end kl 3eme */
1.126     brouard  6825:   
1.223     brouard  6826:   /* 4eme */
1.201     brouard  6827:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  6828:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   6829:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6830:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  6831:        continue;
1.238     brouard  6832:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
                   6833:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   6834:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6835:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6836:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6837:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6838:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6839:          vlv= nbcode[Tvaraff[k]][lv];
                   6840:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6841:        }
                   6842:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6843:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6844:        }       
                   6845:        fprintf(ficgp,"\n#\n");
                   6846:        if(invalidvarcomb[k1]){
                   6847:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6848:          continue;
1.223     brouard  6849:        }
1.238     brouard  6850:       
1.241     brouard  6851:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.238     brouard  6852:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6853: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6854:        k=3;
                   6855:        for (i=1; i<= nlstate ; i ++){
                   6856:          if(i==1){
                   6857:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6858:          }else{
                   6859:            fprintf(ficgp,", '' ");
                   6860:          }
                   6861:          l=(nlstate+ndeath)*(i-1)+1;
                   6862:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6863:          for (j=2; j<= nlstate+ndeath ; j ++)
                   6864:            fprintf(ficgp,"+$%d",k+l+j-1);
                   6865:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   6866:        } /* nlstate */
                   6867:        fprintf(ficgp,"\nset out\n");
                   6868:       } /* end cpt state*/ 
                   6869:     } /* end nres */
                   6870:   } /* end covariate k1 */  
                   6871: 
1.220     brouard  6872: /* 5eme */
1.201     brouard  6873:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  6874:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   6875:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6876:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  6877:        continue;
1.238     brouard  6878:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
                   6879:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   6880:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6881:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6882:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6883:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6884:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6885:          vlv= nbcode[Tvaraff[k]][lv];
                   6886:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6887:        }
                   6888:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6889:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6890:        }       
                   6891:        fprintf(ficgp,"\n#\n");
                   6892:        if(invalidvarcomb[k1]){
                   6893:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6894:          continue;
                   6895:        }
1.227     brouard  6896:       
1.241     brouard  6897:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.238     brouard  6898:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6899: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6900:        k=3;
                   6901:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6902:          if(j==1)
                   6903:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6904:          else
                   6905:            fprintf(ficgp,", '' ");
                   6906:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6907:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   6908:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   6909:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   6910:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   6911:        } /* nlstate */
                   6912:        fprintf(ficgp,", '' ");
                   6913:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   6914:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6915:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6916:          if(j < nlstate)
                   6917:            fprintf(ficgp,"$%d +",k+l);
                   6918:          else
                   6919:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   6920:        }
                   6921:        fprintf(ficgp,"\nset out\n");
                   6922:       } /* end cpt state*/ 
                   6923:     } /* end covariate */  
                   6924:   } /* end nres */
1.227     brouard  6925:   
1.220     brouard  6926: /* 6eme */
1.202     brouard  6927:   /* CV preval stable (period) for each covariate */
1.237     brouard  6928:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6929:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6930:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6931:       continue;
1.255   ! brouard  6932:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.227     brouard  6933:       
1.211     brouard  6934:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  6935:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  6936:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6937:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6938:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6939:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6940:        vlv= nbcode[Tvaraff[k]][lv];
                   6941:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6942:       }
1.237     brouard  6943:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6944:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6945:       }        
1.211     brouard  6946:       fprintf(ficgp,"\n#\n");
1.223     brouard  6947:       if(invalidvarcomb[k1]){
1.227     brouard  6948:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6949:        continue;
1.223     brouard  6950:       }
1.227     brouard  6951:       
1.241     brouard  6952:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.126     brouard  6953:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  6954: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6955:       k=3; /* Offset */
1.255   ! brouard  6956:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  6957:        if(i==1)
                   6958:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6959:        else
                   6960:          fprintf(ficgp,", '' ");
1.255   ! brouard  6961:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  6962:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6963:        for (j=2; j<= nlstate ; j ++)
                   6964:          fprintf(ficgp,"+$%d",k+l+j-1);
                   6965:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  6966:       } /* nlstate */
1.201     brouard  6967:       fprintf(ficgp,"\nset out\n");
1.153     brouard  6968:     } /* end cpt state*/ 
                   6969:   } /* end covariate */  
1.227     brouard  6970:   
                   6971:   
1.220     brouard  6972: /* 7eme */
1.218     brouard  6973:   if(backcast == 1){
1.217     brouard  6974:     /* CV back preval stable (period) for each covariate */
1.237     brouard  6975:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6976:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6977:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6978:        continue;
1.255   ! brouard  6979:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life ending state */
        !          6980:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  6981:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6982:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6983:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6984:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  6985:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  6986:          vlv= nbcode[Tvaraff[k]][lv];
                   6987:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6988:        }
1.237     brouard  6989:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6990:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6991:        }       
1.227     brouard  6992:        fprintf(ficgp,"\n#\n");
                   6993:        if(invalidvarcomb[k1]){
                   6994:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6995:          continue;
                   6996:        }
                   6997:        
1.241     brouard  6998:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.227     brouard  6999:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7000: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7001:        k=3; /* Offset */
1.255   ! brouard  7002:        for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7003:          if(i==1)
                   7004:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7005:          else
                   7006:            fprintf(ficgp,", '' ");
                   7007:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255   ! brouard  7008:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7009:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7010:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255   ! brouard  7011:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7012:          /* for (j=2; j<= nlstate ; j ++) */
                   7013:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7014:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
                   7015:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",i,cpt);
                   7016:        } /* nlstate */
                   7017:        fprintf(ficgp,"\nset out\n");
1.218     brouard  7018:       } /* end cpt state*/ 
                   7019:     } /* end covariate */  
                   7020:   } /* End if backcast */
                   7021:   
1.223     brouard  7022:   /* 8eme */
1.218     brouard  7023:   if(prevfcast==1){
                   7024:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7025:     
1.237     brouard  7026:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7027:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7028:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7029:        continue;
1.211     brouard  7030:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  7031:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7032:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7033:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7034:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7035:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7036:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7037:          vlv= nbcode[Tvaraff[k]][lv];
                   7038:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7039:        }
1.237     brouard  7040:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7041:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7042:        }       
1.227     brouard  7043:        fprintf(ficgp,"\n#\n");
                   7044:        if(invalidvarcomb[k1]){
                   7045:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7046:          continue;
                   7047:        }
                   7048:        
                   7049:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7050:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.227     brouard  7051:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7052: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7053:        for (i=1; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7054:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7055:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7056:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7057:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7058:          if(i==1){
                   7059:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7060:          }else{
                   7061:            fprintf(ficgp,",\\\n '' ");
                   7062:          }
                   7063:          if(cptcoveff ==0){ /* No covariate */
                   7064:            ioffset=2; /* Age is in 2 */
                   7065:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7066:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7067:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7068:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7069:            fprintf(ficgp," u %d:(", ioffset); 
                   7070:            if(i==nlstate+1)
                   7071:              fprintf(ficgp," $%d/(1.-$%d)) t 'pw.%d' with line ",      \
                   7072:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7073:            else
                   7074:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7075:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7076:          }else{ /* more than 2 covariates */
                   7077:            if(cptcoveff ==1){
                   7078:              ioffset=4; /* Age is in 4 */
                   7079:            }else{
                   7080:              ioffset=6; /* Age is in 6 */
                   7081:              /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7082:              /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7083:            }   
                   7084:            fprintf(ficgp," u %d:(",ioffset); 
                   7085:            kl=0;
                   7086:            strcpy(gplotcondition,"(");
                   7087:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7088:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7089:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7090:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7091:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7092:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7093:              kl++;
                   7094:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7095:              kl++;
                   7096:              if(k <cptcoveff && cptcoveff>1)
                   7097:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7098:            }
                   7099:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7100:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7101:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7102:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7103:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7104:            if(i==nlstate+1){
                   7105:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p.%d' with line ", gplotcondition, \
                   7106:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7107:            }else{
                   7108:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7109:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7110:            }
                   7111:          } /* end if covariate */
                   7112:        } /* nlstate */
                   7113:        fprintf(ficgp,"\nset out\n");
1.223     brouard  7114:       } /* end cpt state*/
                   7115:     } /* end covariate */
                   7116:   } /* End if prevfcast */
1.227     brouard  7117:   
                   7118:   
1.238     brouard  7119:   /* 9eme writing MLE parameters */
                   7120:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7121:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7122:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7123:     for(k=1; k <=(nlstate+ndeath); k++){
                   7124:       if (k != i) {
1.227     brouard  7125:        fprintf(ficgp,"#   current state %d\n",k);
                   7126:        for(j=1; j <=ncovmodel; j++){
                   7127:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7128:          jk++; 
                   7129:        }
                   7130:        fprintf(ficgp,"\n");
1.126     brouard  7131:       }
                   7132:     }
1.223     brouard  7133:   }
1.187     brouard  7134:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7135:   
1.145     brouard  7136:   /*goto avoid;*/
1.238     brouard  7137:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7138:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7139:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7140:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7141:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7142:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7143:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7144:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7145:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7146:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7147:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7148:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7149:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7150:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7151:   fprintf(ficgp,"#\n");
1.223     brouard  7152:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7153:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7154:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7155:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.237     brouard  7156:     fprintf(ficgp,"#   jk=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7157:     for(jk=1; jk <=m; jk++)  /* For each combination of covariate */
                   7158:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7159:       if(m != 1 && TKresult[nres]!= jk)
1.237     brouard  7160:        continue;
                   7161:       fprintf(ficgp,"# Combination of dummy  jk=%d and ",jk);
                   7162:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7163:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7164:       }        
                   7165:       fprintf(ficgp,"\n#\n");
1.241     brouard  7166:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng,nres);
1.223     brouard  7167:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7168:       if (ng==1){
                   7169:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7170:        fprintf(ficgp,"\nunset log y");
                   7171:       }else if (ng==2){
                   7172:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7173:        fprintf(ficgp,"\nset log y");
                   7174:       }else if (ng==3){
                   7175:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7176:        fprintf(ficgp,"\nset log y");
                   7177:       }else
                   7178:        fprintf(ficgp,"\nunset title ");
                   7179:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7180:       i=1;
                   7181:       for(k2=1; k2<=nlstate; k2++) {
                   7182:        k3=i;
                   7183:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7184:          if (k != k2){
                   7185:            switch( ng) {
                   7186:            case 1:
                   7187:              if(nagesqr==0)
                   7188:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7189:              else /* nagesqr =1 */
                   7190:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7191:              break;
                   7192:            case 2: /* ng=2 */
                   7193:              if(nagesqr==0)
                   7194:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7195:              else /* nagesqr =1 */
                   7196:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7197:              break;
                   7198:            case 3:
                   7199:              if(nagesqr==0)
                   7200:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7201:              else /* nagesqr =1 */
                   7202:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7203:              break;
                   7204:            }
                   7205:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7206:            ijp=1; /* product no age */
                   7207:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7208:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7209:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.237     brouard  7210:              if(j==Tage[ij]) { /* Product by age */
                   7211:                if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
1.238     brouard  7212:                  if(DummyV[j]==0){
1.237     brouard  7213:                    fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7214:                  }else{ /* quantitative */
                   7215:                    fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7216:                    /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7217:                  }
                   7218:                  ij++;
                   7219:                }
                   7220:              }else if(j==Tprod[ijp]) { /* */ 
                   7221:                /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7222:                if(ijp <=cptcovprod) { /* Product */
1.238     brouard  7223:                  if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7224:                    if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
1.237     brouard  7225:                      /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],nbcode[Tvard[ijp][2]][codtabm(jk,j)]); */
                   7226:                      fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7227:                    }else{ /* Vn is dummy and Vm is quanti */
                   7228:                      /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7229:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7230:                    }
                   7231:                  }else{ /* Vn*Vm Vn is quanti */
1.238     brouard  7232:                    if(DummyV[Tvard[ijp][2]]==0){
1.237     brouard  7233:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7234:                    }else{ /* Both quanti */
                   7235:                      fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7236:                    }
                   7237:                  }
1.238     brouard  7238:                  ijp++;
1.237     brouard  7239:                }
                   7240:              } else{  /* simple covariate */
                   7241:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(jk,j)]); /\* Valgrind bug nbcode *\/ */
                   7242:                if(Dummy[j]==0){
                   7243:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7244:                }else{ /* quantitative */
                   7245:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.223     brouard  7246:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7247:                }
1.237     brouard  7248:              } /* end simple */
                   7249:            } /* end j */
1.223     brouard  7250:          }else{
                   7251:            i=i-ncovmodel;
                   7252:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7253:              fprintf(ficgp," (1.");
                   7254:          }
1.227     brouard  7255:          
1.223     brouard  7256:          if(ng != 1){
                   7257:            fprintf(ficgp,")/(1");
1.227     brouard  7258:            
1.223     brouard  7259:            for(k1=1; k1 <=nlstate; k1++){ 
                   7260:              if(nagesqr==0)
                   7261:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                   7262:              else /* nagesqr =1 */
                   7263:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1,k3+(k1-1)*ncovmodel+1+nagesqr);
1.217     brouard  7264:               
1.223     brouard  7265:              ij=1;
                   7266:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.237     brouard  7267:                if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7268:                  if(ij <=cptcovage) { /* Bug valgrind */
1.223     brouard  7269:                    fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                   7270:                    /* fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7271:                    ij++;
                   7272:                  }
                   7273:                }
                   7274:                else
1.225     brouard  7275:                  fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7276:              }
                   7277:              fprintf(ficgp,")");
                   7278:            }
                   7279:            fprintf(ficgp,")");
                   7280:            if(ng ==2)
                   7281:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   7282:            else /* ng= 3 */
                   7283:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   7284:          }else{ /* end ng <> 1 */
                   7285:            if( k !=k2) /* logit p11 is hard to draw */
                   7286:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   7287:          }
                   7288:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7289:            fprintf(ficgp,",");
                   7290:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7291:            fprintf(ficgp,",");
                   7292:          i=i+ncovmodel;
                   7293:        } /* end k */
                   7294:       } /* end k2 */
                   7295:       fprintf(ficgp,"\n set out\n");
                   7296:     } /* end jk */
                   7297:   } /* end ng */
                   7298:   /* avoid: */
                   7299:   fflush(ficgp); 
1.126     brouard  7300: }  /* end gnuplot */
                   7301: 
                   7302: 
                   7303: /*************** Moving average **************/
1.219     brouard  7304: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  7305:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  7306:    
1.222     brouard  7307:    int i, cpt, cptcod;
                   7308:    int modcovmax =1;
                   7309:    int mobilavrange, mob;
                   7310:    int iage=0;
                   7311: 
                   7312:    double sum=0.;
                   7313:    double age;
                   7314:    double *sumnewp, *sumnewm;
                   7315:    double *agemingood, *agemaxgood; /* Currently identical for all covariates */
                   7316:   
                   7317:   
1.225     brouard  7318:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  7319:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   7320: 
                   7321:    sumnewp = vector(1,ncovcombmax);
                   7322:    sumnewm = vector(1,ncovcombmax);
                   7323:    agemingood = vector(1,ncovcombmax); 
                   7324:    agemaxgood = vector(1,ncovcombmax);
                   7325: 
                   7326:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7327:      sumnewm[cptcod]=0.;
                   7328:      sumnewp[cptcod]=0.;
                   7329:      agemingood[cptcod]=0;
                   7330:      agemaxgood[cptcod]=0;
                   7331:    }
                   7332:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   7333:   
                   7334:    if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   7335:      if(mobilav==1) mobilavrange=5; /* default */
                   7336:      else mobilavrange=mobilav;
                   7337:      for (age=bage; age<=fage; age++)
                   7338:        for (i=1; i<=nlstate;i++)
                   7339:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   7340:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   7341:      /* We keep the original values on the extreme ages bage, fage and for 
                   7342:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   7343:        we use a 5 terms etc. until the borders are no more concerned. 
                   7344:      */ 
                   7345:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   7346:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
                   7347:         for (i=1; i<=nlstate;i++){
                   7348:           for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7349:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   7350:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   7351:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   7352:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   7353:             }
                   7354:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
                   7355:           }
                   7356:         }
                   7357:        }/* end age */
                   7358:      }/* end mob */
                   7359:    }else
                   7360:      return -1;
                   7361:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7362:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7363:      if(invalidvarcomb[cptcod]){
                   7364:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7365:        continue;
                   7366:      }
1.219     brouard  7367: 
1.222     brouard  7368:      agemingood[cptcod]=fage-(mob-1)/2;
                   7369:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, finding the youngest wrong */
                   7370:        sumnewm[cptcod]=0.;
                   7371:        for (i=1; i<=nlstate;i++){
                   7372:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7373:        }
                   7374:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7375:         agemingood[cptcod]=age;
                   7376:        }else{ /* bad */
                   7377:         for (i=1; i<=nlstate;i++){
                   7378:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7379:         } /* i */
                   7380:        } /* end bad */
                   7381:      }/* age */
                   7382:      sum=0.;
                   7383:      for (i=1; i<=nlstate;i++){
                   7384:        sum+=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7385:      }
                   7386:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7387:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any descending age!\n",cptcod);
                   7388:        /* for (i=1; i<=nlstate;i++){ */
                   7389:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7390:        /* } /\* i *\/ */
                   7391:      } /* end bad */
                   7392:      /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   7393:      /* From youngest, finding the oldest wrong */
                   7394:      agemaxgood[cptcod]=bage+(mob-1)/2;
                   7395:      for (age=bage+(mob-1)/2; age<=fage; age++){
                   7396:        sumnewm[cptcod]=0.;
                   7397:        for (i=1; i<=nlstate;i++){
                   7398:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7399:        }
                   7400:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7401:         agemaxgood[cptcod]=age;
                   7402:        }else{ /* bad */
                   7403:         for (i=1; i<=nlstate;i++){
                   7404:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7405:         } /* i */
                   7406:        } /* end bad */
                   7407:      }/* age */
                   7408:      sum=0.;
                   7409:      for (i=1; i<=nlstate;i++){
                   7410:        sum+=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7411:      }
                   7412:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7413:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any ascending age!\n",cptcod);
                   7414:        /* for (i=1; i<=nlstate;i++){ */
                   7415:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7416:        /* } /\* i *\/ */
                   7417:      } /* end bad */
                   7418:                
                   7419:      for (age=bage; age<=fage; age++){
1.235     brouard  7420:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  7421:        sumnewp[cptcod]=0.;
                   7422:        sumnewm[cptcod]=0.;
                   7423:        for (i=1; i<=nlstate;i++){
                   7424:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   7425:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7426:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   7427:        }
                   7428:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   7429:      }
                   7430:      /* printf("\n"); */
                   7431:      /* } */
                   7432:      /* brutal averaging */
                   7433:      for (i=1; i<=nlstate;i++){
                   7434:        for (age=1; age<=bage; age++){
                   7435:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7436:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7437:        }       
                   7438:        for (age=fage; age<=AGESUP; age++){
                   7439:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7440:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7441:        }
                   7442:      } /* end i status */
                   7443:      for (i=nlstate+1; i<=nlstate+ndeath;i++){
                   7444:        for (age=1; age<=AGESUP; age++){
                   7445:         /*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*/
                   7446:         mobaverage[(int)age][i][cptcod]=0.;
                   7447:        }
                   7448:      }
                   7449:    }/* end cptcod */
                   7450:    free_vector(sumnewm,1, ncovcombmax);
                   7451:    free_vector(sumnewp,1, ncovcombmax);
                   7452:    free_vector(agemaxgood,1, ncovcombmax);
                   7453:    free_vector(agemingood,1, ncovcombmax);
                   7454:    return 0;
                   7455:  }/* End movingaverage */
1.218     brouard  7456:  
1.126     brouard  7457: 
                   7458: /************** Forecasting ******************/
1.235     brouard  7459:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  7460:   /* proj1, year, month, day of starting projection 
                   7461:      agemin, agemax range of age
                   7462:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   7463:      anproj2 year of en of projection (same day and month as proj1).
                   7464:   */
1.235     brouard  7465:    int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  7466:   double agec; /* generic age */
                   7467:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   7468:   double *popeffectif,*popcount;
                   7469:   double ***p3mat;
1.218     brouard  7470:   /* double ***mobaverage; */
1.126     brouard  7471:   char fileresf[FILENAMELENGTH];
                   7472: 
                   7473:   agelim=AGESUP;
1.211     brouard  7474:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   7475:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   7476:      We still use firstpass and lastpass as another selection.
                   7477:   */
1.214     brouard  7478:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   7479:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  7480:  
1.201     brouard  7481:   strcpy(fileresf,"F_"); 
                   7482:   strcat(fileresf,fileresu);
1.126     brouard  7483:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   7484:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   7485:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   7486:   }
1.235     brouard  7487:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   7488:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  7489: 
1.225     brouard  7490:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  7491: 
                   7492: 
                   7493:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   7494:   if (stepm<=12) stepsize=1;
                   7495:   if(estepm < stepm){
                   7496:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   7497:   }
                   7498:   else  hstepm=estepm;   
                   7499: 
                   7500:   hstepm=hstepm/stepm; 
                   7501:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   7502:                                fractional in yp1 */
                   7503:   anprojmean=yp;
                   7504:   yp2=modf((yp1*12),&yp);
                   7505:   mprojmean=yp;
                   7506:   yp1=modf((yp2*30.5),&yp);
                   7507:   jprojmean=yp;
                   7508:   if(jprojmean==0) jprojmean=1;
                   7509:   if(mprojmean==0) jprojmean=1;
                   7510: 
1.227     brouard  7511:   i1=pow(2,cptcoveff);
1.126     brouard  7512:   if (cptcovn < 1){i1=1;}
                   7513:   
                   7514:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   7515:   
                   7516:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  7517:   
1.126     brouard  7518: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  7519:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7520:   for(k=1; k<=i1;k++){
1.253     brouard  7521:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  7522:       continue;
1.227     brouard  7523:     if(invalidvarcomb[k]){
                   7524:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   7525:       continue;
                   7526:     }
                   7527:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   7528:     for(j=1;j<=cptcoveff;j++) {
                   7529:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7530:     }
1.235     brouard  7531:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7532:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  7533:     }
1.227     brouard  7534:     fprintf(ficresf," yearproj age");
                   7535:     for(j=1; j<=nlstate+ndeath;j++){ 
                   7536:       for(i=1; i<=nlstate;i++)               
                   7537:        fprintf(ficresf," p%d%d",i,j);
                   7538:       fprintf(ficresf," wp.%d",j);
                   7539:     }
                   7540:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   7541:       fprintf(ficresf,"\n");
                   7542:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
                   7543:       for (agec=fage; agec>=(ageminpar-1); agec--){ 
                   7544:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   7545:        nhstepm = nhstepm/hstepm; 
                   7546:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7547:        oldm=oldms;savm=savms;
1.235     brouard  7548:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.227     brouard  7549:        
                   7550:        for (h=0; h<=nhstepm; h++){
                   7551:          if (h*hstepm/YEARM*stepm ==yearp) {
                   7552:            fprintf(ficresf,"\n");
                   7553:            for(j=1;j<=cptcoveff;j++) 
                   7554:              fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7555:            fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   7556:          } 
                   7557:          for(j=1; j<=nlstate+ndeath;j++) {
                   7558:            ppij=0.;
                   7559:            for(i=1; i<=nlstate;i++) {
                   7560:              if (mobilav==1) 
                   7561:                ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][k];
                   7562:              else {
                   7563:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   7564:              }
                   7565:              if (h*hstepm/YEARM*stepm== yearp) {
                   7566:                fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   7567:              }
                   7568:            } /* end i */
                   7569:            if (h*hstepm/YEARM*stepm==yearp) {
                   7570:              fprintf(ficresf," %.3f", ppij);
                   7571:            }
                   7572:          }/* end j */
                   7573:        } /* end h */
                   7574:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7575:       } /* end agec */
                   7576:     } /* end yearp */
                   7577:   } /* end  k */
1.219     brouard  7578:        
1.126     brouard  7579:   fclose(ficresf);
1.215     brouard  7580:   printf("End of Computing forecasting \n");
                   7581:   fprintf(ficlog,"End of Computing forecasting\n");
                   7582: 
1.126     brouard  7583: }
                   7584: 
1.218     brouard  7585: /* /\************** Back Forecasting ******************\/ */
1.225     brouard  7586: /* void prevbackforecast(char fileres[], double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
1.218     brouard  7587: /*   /\* back1, year, month, day of starting backection  */
                   7588: /*      agemin, agemax range of age */
                   7589: /*      dateprev1 dateprev2 range of dates during which prevalence is computed */
                   7590: /*      anback2 year of en of backection (same day and month as back1). */
                   7591: /*   *\/ */
                   7592: /*   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1; */
                   7593: /*   double agec; /\* generic age *\/ */
                   7594: /*   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean; */
                   7595: /*   double *popeffectif,*popcount; */
                   7596: /*   double ***p3mat; */
                   7597: /*   /\* double ***mobaverage; *\/ */
                   7598: /*   char fileresfb[FILENAMELENGTH]; */
                   7599:        
                   7600: /*   agelim=AGESUP; */
                   7601: /*   /\* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people */
                   7602: /*      in each health status at the date of interview (if between dateprev1 and dateprev2). */
                   7603: /*      We still use firstpass and lastpass as another selection. */
                   7604: /*   *\/ */
                   7605: /*   /\* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ *\/ */
                   7606: /*   /\*             firstpass, lastpass,  stepm,  weightopt, model); *\/ */
                   7607: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   7608:        
                   7609: /*   strcpy(fileresfb,"FB_");  */
                   7610: /*   strcat(fileresfb,fileresu); */
                   7611: /*   if((ficresfb=fopen(fileresfb,"w"))==NULL) { */
                   7612: /*     printf("Problem with back forecast resultfile: %s\n", fileresfb); */
                   7613: /*     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb); */
                   7614: /*   } */
                   7615: /*   printf("Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7616: /*   fprintf(ficlog,"Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7617:        
1.225     brouard  7618: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.218     brouard  7619:        
                   7620: /*   /\* if (mobilav!=0) { *\/ */
                   7621: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7622: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7623: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7624: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7625: /*   /\*   } *\/ */
                   7626: /*   /\* } *\/ */
                   7627:        
                   7628: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7629: /*   if (stepm<=12) stepsize=1; */
                   7630: /*   if(estepm < stepm){ */
                   7631: /*     printf ("Problem %d lower than %d\n",estepm, stepm); */
                   7632: /*   } */
                   7633: /*   else  hstepm=estepm;    */
                   7634:        
                   7635: /*   hstepm=hstepm/stepm;  */
                   7636: /*   yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   7637: /*                                fractional in yp1 *\/ */
                   7638: /*   anprojmean=yp; */
                   7639: /*   yp2=modf((yp1*12),&yp); */
                   7640: /*   mprojmean=yp; */
                   7641: /*   yp1=modf((yp2*30.5),&yp); */
                   7642: /*   jprojmean=yp; */
                   7643: /*   if(jprojmean==0) jprojmean=1; */
                   7644: /*   if(mprojmean==0) jprojmean=1; */
                   7645:        
1.225     brouard  7646: /*   i1=cptcoveff; */
1.218     brouard  7647: /*   if (cptcovn < 1){i1=1;} */
1.217     brouard  7648:   
1.218     brouard  7649: /*   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);  */
1.217     brouard  7650:   
1.218     brouard  7651: /*   fprintf(ficresfb,"#****** Routine prevbackforecast **\n"); */
                   7652:        
                   7653: /*     /\*           if (h==(int)(YEARM*yearp)){ *\/ */
                   7654: /*   for(cptcov=1, k=0;cptcov<=i1;cptcov++){ */
1.225     brouard  7655: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
1.218     brouard  7656: /*       k=k+1; */
                   7657: /*       fprintf(ficresfb,"\n#****** hbijx=probability over h years, hp.jx is weighted by observed prev \n#"); */
1.225     brouard  7658: /*       for(j=1;j<=cptcoveff;j++) { */
1.218     brouard  7659: /*                             fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7660: /*       } */
                   7661: /*       fprintf(ficresfb," yearbproj age"); */
                   7662: /*       for(j=1; j<=nlstate+ndeath;j++){  */
                   7663: /*                             for(i=1; i<=nlstate;i++)               */
                   7664: /*           fprintf(ficresfb," p%d%d",i,j); */
                   7665: /*                             fprintf(ficresfb," p.%d",j); */
                   7666: /*       } */
                   7667: /*       for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {  */
                   7668: /*                             /\* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  *\/ */
                   7669: /*                             fprintf(ficresfb,"\n"); */
                   7670: /*                             fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);    */
                   7671: /*                             for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   7672: /*                                     nhstepm=(int) rint((agelim-agec)*YEARM/stepm);  */
                   7673: /*                                     nhstepm = nhstepm/hstepm;  */
                   7674: /*                                     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7675: /*                                     oldm=oldms;savm=savms; */
                   7676: /*                                     hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm,oldm,savm, dnewm, doldm, dsavm, k);       */
                   7677: /*                                     for (h=0; h<=nhstepm; h++){ */
                   7678: /*                                             if (h*hstepm/YEARM*stepm ==yearp) { */
                   7679: /*               fprintf(ficresfb,"\n"); */
1.225     brouard  7680: /*               for(j=1;j<=cptcoveff;j++)  */
1.218     brouard  7681: /*                 fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7682: /*                                                     fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec+h*hstepm/YEARM*stepm); */
                   7683: /*                                             }  */
                   7684: /*                                             for(j=1; j<=nlstate+ndeath;j++) { */
                   7685: /*                                                     ppij=0.; */
                   7686: /*                                                     for(i=1; i<=nlstate;i++) { */
                   7687: /*                                                             if (mobilav==1)  */
                   7688: /*                                                                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod]; */
                   7689: /*                                                             else { */
                   7690: /*                                                                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod]; */
                   7691: /*                                                             } */
                   7692: /*                                                             if (h*hstepm/YEARM*stepm== yearp) { */
                   7693: /*                                                                     fprintf(ficresfb," %.3f", p3mat[i][j][h]); */
                   7694: /*                                                             } */
                   7695: /*                                                     } /\* end i *\/ */
                   7696: /*                                                     if (h*hstepm/YEARM*stepm==yearp) { */
                   7697: /*                                                             fprintf(ficresfb," %.3f", ppij); */
                   7698: /*                                                     } */
                   7699: /*                                             }/\* end j *\/ */
                   7700: /*                                     } /\* end h *\/ */
                   7701: /*                                     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7702: /*                             } /\* end agec *\/ */
                   7703: /*       } /\* end yearp *\/ */
                   7704: /*     } /\* end cptcod *\/ */
                   7705: /*   } /\* end  cptcov *\/ */
                   7706:        
                   7707: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7708:        
                   7709: /*   fclose(ficresfb); */
                   7710: /*   printf("End of Computing Back forecasting \n"); */
                   7711: /*   fprintf(ficlog,"End of Computing Back forecasting\n"); */
1.217     brouard  7712:        
1.218     brouard  7713: /* } */
1.217     brouard  7714: 
1.126     brouard  7715: /************** Forecasting *****not tested NB*************/
1.227     brouard  7716: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  7717:   
1.227     brouard  7718: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   7719: /*   int *popage; */
                   7720: /*   double calagedatem, agelim, kk1, kk2; */
                   7721: /*   double *popeffectif,*popcount; */
                   7722: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   7723: /*   /\* double ***mobaverage; *\/ */
                   7724: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  7725: 
1.227     brouard  7726: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7727: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7728: /*   agelim=AGESUP; */
                   7729: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  7730:   
1.227     brouard  7731: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  7732:   
                   7733:   
1.227     brouard  7734: /*   strcpy(filerespop,"POP_");  */
                   7735: /*   strcat(filerespop,fileresu); */
                   7736: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   7737: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   7738: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   7739: /*   } */
                   7740: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   7741: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  7742: 
1.227     brouard  7743: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  7744: 
1.227     brouard  7745: /*   /\* if (mobilav!=0) { *\/ */
                   7746: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7747: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7748: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7749: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7750: /*   /\*   } *\/ */
                   7751: /*   /\* } *\/ */
1.126     brouard  7752: 
1.227     brouard  7753: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7754: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  7755:   
1.227     brouard  7756: /*   agelim=AGESUP; */
1.126     brouard  7757:   
1.227     brouard  7758: /*   hstepm=1; */
                   7759: /*   hstepm=hstepm/stepm;  */
1.218     brouard  7760:        
1.227     brouard  7761: /*   if (popforecast==1) { */
                   7762: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   7763: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   7764: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   7765: /*     }  */
                   7766: /*     popage=ivector(0,AGESUP); */
                   7767: /*     popeffectif=vector(0,AGESUP); */
                   7768: /*     popcount=vector(0,AGESUP); */
1.126     brouard  7769:     
1.227     brouard  7770: /*     i=1;    */
                   7771: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  7772:     
1.227     brouard  7773: /*     imx=i; */
                   7774: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   7775: /*   } */
1.218     brouard  7776:   
1.227     brouard  7777: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   7778: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   7779: /*       k=k+1; */
                   7780: /*       fprintf(ficrespop,"\n#******"); */
                   7781: /*       for(j=1;j<=cptcoveff;j++) { */
                   7782: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7783: /*       } */
                   7784: /*       fprintf(ficrespop,"******\n"); */
                   7785: /*       fprintf(ficrespop,"# Age"); */
                   7786: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   7787: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  7788:       
1.227     brouard  7789: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   7790: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  7791:        
1.227     brouard  7792: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7793: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7794: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7795:          
1.227     brouard  7796: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7797: /*       oldm=oldms;savm=savms; */
                   7798: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  7799:          
1.227     brouard  7800: /*       for (h=0; h<=nhstepm; h++){ */
                   7801: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7802: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7803: /*         }  */
                   7804: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7805: /*           kk1=0.;kk2=0; */
                   7806: /*           for(i=1; i<=nlstate;i++) {               */
                   7807: /*             if (mobilav==1)  */
                   7808: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   7809: /*             else { */
                   7810: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   7811: /*             } */
                   7812: /*           } */
                   7813: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   7814: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   7815: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   7816: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   7817: /*           } */
                   7818: /*         } */
                   7819: /*         for(i=1; i<=nlstate;i++){ */
                   7820: /*           kk1=0.; */
                   7821: /*           for(j=1; j<=nlstate;j++){ */
                   7822: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   7823: /*           } */
                   7824: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   7825: /*         } */
1.218     brouard  7826:            
1.227     brouard  7827: /*         if (h==(int)(calagedatem+12*cpt)) */
                   7828: /*           for(j=1; j<=nlstate;j++)  */
                   7829: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   7830: /*       } */
                   7831: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7832: /*     } */
                   7833: /*       } */
1.218     brouard  7834:       
1.227     brouard  7835: /*       /\******\/ */
1.218     brouard  7836:       
1.227     brouard  7837: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   7838: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   7839: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7840: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7841: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7842:          
1.227     brouard  7843: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7844: /*       oldm=oldms;savm=savms; */
                   7845: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   7846: /*       for (h=0; h<=nhstepm; h++){ */
                   7847: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7848: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7849: /*         }  */
                   7850: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7851: /*           kk1=0.;kk2=0; */
                   7852: /*           for(i=1; i<=nlstate;i++) {               */
                   7853: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   7854: /*           } */
                   7855: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   7856: /*         } */
                   7857: /*       } */
                   7858: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7859: /*     } */
                   7860: /*       } */
                   7861: /*     }  */
                   7862: /*   } */
1.218     brouard  7863:   
1.227     brouard  7864: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  7865:   
1.227     brouard  7866: /*   if (popforecast==1) { */
                   7867: /*     free_ivector(popage,0,AGESUP); */
                   7868: /*     free_vector(popeffectif,0,AGESUP); */
                   7869: /*     free_vector(popcount,0,AGESUP); */
                   7870: /*   } */
                   7871: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7872: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7873: /*   fclose(ficrespop); */
                   7874: /* } /\* End of popforecast *\/ */
1.218     brouard  7875:  
1.126     brouard  7876: int fileappend(FILE *fichier, char *optionfich)
                   7877: {
                   7878:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   7879:     printf("Problem with file: %s\n", optionfich);
                   7880:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   7881:     return (0);
                   7882:   }
                   7883:   fflush(fichier);
                   7884:   return (1);
                   7885: }
                   7886: 
                   7887: 
                   7888: /**************** function prwizard **********************/
                   7889: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   7890: {
                   7891: 
                   7892:   /* Wizard to print covariance matrix template */
                   7893: 
1.164     brouard  7894:   char ca[32], cb[32];
                   7895:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  7896:   int numlinepar;
                   7897: 
                   7898:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7899:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7900:   for(i=1; i <=nlstate; i++){
                   7901:     jj=0;
                   7902:     for(j=1; j <=nlstate+ndeath; j++){
                   7903:       if(j==i) continue;
                   7904:       jj++;
                   7905:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   7906:       printf("%1d%1d",i,j);
                   7907:       fprintf(ficparo,"%1d%1d",i,j);
                   7908:       for(k=1; k<=ncovmodel;k++){
                   7909:        /*        printf(" %lf",param[i][j][k]); */
                   7910:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   7911:        printf(" 0.");
                   7912:        fprintf(ficparo," 0.");
                   7913:       }
                   7914:       printf("\n");
                   7915:       fprintf(ficparo,"\n");
                   7916:     }
                   7917:   }
                   7918:   printf("# Scales (for hessian or gradient estimation)\n");
                   7919:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   7920:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   7921:   for(i=1; i <=nlstate; i++){
                   7922:     jj=0;
                   7923:     for(j=1; j <=nlstate+ndeath; j++){
                   7924:       if(j==i) continue;
                   7925:       jj++;
                   7926:       fprintf(ficparo,"%1d%1d",i,j);
                   7927:       printf("%1d%1d",i,j);
                   7928:       fflush(stdout);
                   7929:       for(k=1; k<=ncovmodel;k++){
                   7930:        /*      printf(" %le",delti3[i][j][k]); */
                   7931:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   7932:        printf(" 0.");
                   7933:        fprintf(ficparo," 0.");
                   7934:       }
                   7935:       numlinepar++;
                   7936:       printf("\n");
                   7937:       fprintf(ficparo,"\n");
                   7938:     }
                   7939:   }
                   7940:   printf("# Covariance matrix\n");
                   7941: /* # 121 Var(a12)\n\ */
                   7942: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7943: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   7944: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   7945: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   7946: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   7947: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   7948: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   7949:   fflush(stdout);
                   7950:   fprintf(ficparo,"# Covariance matrix\n");
                   7951:   /* # 121 Var(a12)\n\ */
                   7952:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7953:   /* #   ...\n\ */
                   7954:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   7955:   
                   7956:   for(itimes=1;itimes<=2;itimes++){
                   7957:     jj=0;
                   7958:     for(i=1; i <=nlstate; i++){
                   7959:       for(j=1; j <=nlstate+ndeath; j++){
                   7960:        if(j==i) continue;
                   7961:        for(k=1; k<=ncovmodel;k++){
                   7962:          jj++;
                   7963:          ca[0]= k+'a'-1;ca[1]='\0';
                   7964:          if(itimes==1){
                   7965:            printf("#%1d%1d%d",i,j,k);
                   7966:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   7967:          }else{
                   7968:            printf("%1d%1d%d",i,j,k);
                   7969:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   7970:            /*  printf(" %.5le",matcov[i][j]); */
                   7971:          }
                   7972:          ll=0;
                   7973:          for(li=1;li <=nlstate; li++){
                   7974:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   7975:              if(lj==li) continue;
                   7976:              for(lk=1;lk<=ncovmodel;lk++){
                   7977:                ll++;
                   7978:                if(ll<=jj){
                   7979:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   7980:                  if(ll<jj){
                   7981:                    if(itimes==1){
                   7982:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7983:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7984:                    }else{
                   7985:                      printf(" 0.");
                   7986:                      fprintf(ficparo," 0.");
                   7987:                    }
                   7988:                  }else{
                   7989:                    if(itimes==1){
                   7990:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   7991:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   7992:                    }else{
                   7993:                      printf(" 0.");
                   7994:                      fprintf(ficparo," 0.");
                   7995:                    }
                   7996:                  }
                   7997:                }
                   7998:              } /* end lk */
                   7999:            } /* end lj */
                   8000:          } /* end li */
                   8001:          printf("\n");
                   8002:          fprintf(ficparo,"\n");
                   8003:          numlinepar++;
                   8004:        } /* end k*/
                   8005:       } /*end j */
                   8006:     } /* end i */
                   8007:   } /* end itimes */
                   8008: 
                   8009: } /* end of prwizard */
                   8010: /******************* Gompertz Likelihood ******************************/
                   8011: double gompertz(double x[])
                   8012: { 
                   8013:   double A,B,L=0.0,sump=0.,num=0.;
                   8014:   int i,n=0; /* n is the size of the sample */
                   8015: 
1.220     brouard  8016:   for (i=1;i<=imx ; i++) {
1.126     brouard  8017:     sump=sump+weight[i];
                   8018:     /*    sump=sump+1;*/
                   8019:     num=num+1;
                   8020:   }
                   8021:  
                   8022:  
                   8023:   /* for (i=0; i<=imx; i++) 
                   8024:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8025: 
                   8026:   for (i=1;i<=imx ; i++)
                   8027:     {
                   8028:       if (cens[i] == 1 && wav[i]>1)
                   8029:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8030:       
                   8031:       if (cens[i] == 0 && wav[i]>1)
                   8032:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8033:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8034:       
                   8035:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8036:       if (wav[i] > 1 ) { /* ??? */
                   8037:        L=L+A*weight[i];
                   8038:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8039:       }
                   8040:     }
                   8041: 
                   8042:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8043:  
                   8044:   return -2*L*num/sump;
                   8045: }
                   8046: 
1.136     brouard  8047: #ifdef GSL
                   8048: /******************* Gompertz_f Likelihood ******************************/
                   8049: double gompertz_f(const gsl_vector *v, void *params)
                   8050: { 
                   8051:   double A,B,LL=0.0,sump=0.,num=0.;
                   8052:   double *x= (double *) v->data;
                   8053:   int i,n=0; /* n is the size of the sample */
                   8054: 
                   8055:   for (i=0;i<=imx-1 ; i++) {
                   8056:     sump=sump+weight[i];
                   8057:     /*    sump=sump+1;*/
                   8058:     num=num+1;
                   8059:   }
                   8060:  
                   8061:  
                   8062:   /* for (i=0; i<=imx; i++) 
                   8063:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8064:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   8065:   for (i=1;i<=imx ; i++)
                   8066:     {
                   8067:       if (cens[i] == 1 && wav[i]>1)
                   8068:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   8069:       
                   8070:       if (cens[i] == 0 && wav[i]>1)
                   8071:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   8072:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   8073:       
                   8074:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8075:       if (wav[i] > 1 ) { /* ??? */
                   8076:        LL=LL+A*weight[i];
                   8077:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8078:       }
                   8079:     }
                   8080: 
                   8081:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8082:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   8083:  
                   8084:   return -2*LL*num/sump;
                   8085: }
                   8086: #endif
                   8087: 
1.126     brouard  8088: /******************* Printing html file ***********/
1.201     brouard  8089: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  8090:                  int lastpass, int stepm, int weightopt, char model[],\
                   8091:                  int imx,  double p[],double **matcov,double agemortsup){
                   8092:   int i,k;
                   8093: 
                   8094:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   8095:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   8096:   for (i=1;i<=2;i++) 
                   8097:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  8098:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  8099:   fprintf(fichtm,"</ul>");
                   8100: 
                   8101: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   8102: 
                   8103:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   8104: 
                   8105:  for (k=agegomp;k<(agemortsup-2);k++) 
                   8106:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   8107: 
                   8108:  
                   8109:   fflush(fichtm);
                   8110: }
                   8111: 
                   8112: /******************* Gnuplot file **************/
1.201     brouard  8113: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  8114: 
                   8115:   char dirfileres[132],optfileres[132];
1.164     brouard  8116: 
1.126     brouard  8117:   int ng;
                   8118: 
                   8119: 
                   8120:   /*#ifdef windows */
                   8121:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   8122:     /*#endif */
                   8123: 
                   8124: 
                   8125:   strcpy(dirfileres,optionfilefiname);
                   8126:   strcpy(optfileres,"vpl");
1.199     brouard  8127:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  8128:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  8129:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  8130:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  8131:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   8132: 
                   8133: } 
                   8134: 
1.136     brouard  8135: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   8136: {
1.126     brouard  8137: 
1.136     brouard  8138:   /*-------- data file ----------*/
                   8139:   FILE *fic;
                   8140:   char dummy[]="                         ";
1.240     brouard  8141:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  8142:   int lstra;
1.136     brouard  8143:   int linei, month, year,iout;
                   8144:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  8145:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  8146:   char *stratrunc;
1.223     brouard  8147: 
1.240     brouard  8148:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   8149:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  8150: 
1.240     brouard  8151:   for(v=1; v <=ncovcol;v++){
                   8152:     DummyV[v]=0;
                   8153:     FixedV[v]=0;
                   8154:   }
                   8155:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   8156:     DummyV[v]=1;
                   8157:     FixedV[v]=0;
                   8158:   }
                   8159:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   8160:     DummyV[v]=0;
                   8161:     FixedV[v]=1;
                   8162:   }
                   8163:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8164:     DummyV[v]=1;
                   8165:     FixedV[v]=1;
                   8166:   }
                   8167:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8168:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8169:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8170:   }
1.126     brouard  8171: 
1.136     brouard  8172:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  8173:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   8174:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  8175:   }
1.126     brouard  8176: 
1.136     brouard  8177:   i=1;
                   8178:   linei=0;
                   8179:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   8180:     linei=linei+1;
                   8181:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   8182:       if(line[j] == '\t')
                   8183:        line[j] = ' ';
                   8184:     }
                   8185:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   8186:       ;
                   8187:     };
                   8188:     line[j+1]=0;  /* Trims blanks at end of line */
                   8189:     if(line[0]=='#'){
                   8190:       fprintf(ficlog,"Comment line\n%s\n",line);
                   8191:       printf("Comment line\n%s\n",line);
                   8192:       continue;
                   8193:     }
                   8194:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  8195:     strcpy(line, linetmp);
1.223     brouard  8196:     
                   8197:     /* Loops on waves */
                   8198:     for (j=maxwav;j>=1;j--){
                   8199:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  8200:        cutv(stra, strb, line, ' '); 
                   8201:        if(strb[0]=='.') { /* Missing value */
                   8202:          lval=-1;
                   8203:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   8204:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   8205:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   8206:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   8207:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   8208:            return 1;
                   8209:          }
                   8210:        }else{
                   8211:          errno=0;
                   8212:          /* what_kind_of_number(strb); */
                   8213:          dval=strtod(strb,&endptr); 
                   8214:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   8215:          /* if(strb != endptr && *endptr == '\0') */
                   8216:          /*    dval=dlval; */
                   8217:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8218:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8219:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   8220:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   8221:            return 1;
                   8222:          }
                   8223:          cotqvar[j][iv][i]=dval; 
                   8224:          cotvar[j][ntv+iv][i]=dval; 
                   8225:        }
                   8226:        strcpy(line,stra);
1.223     brouard  8227:       }/* end loop ntqv */
1.225     brouard  8228:       
1.223     brouard  8229:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  8230:        cutv(stra, strb, line, ' '); 
                   8231:        if(strb[0]=='.') { /* Missing value */
                   8232:          lval=-1;
                   8233:        }else{
                   8234:          errno=0;
                   8235:          lval=strtol(strb,&endptr,10); 
                   8236:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8237:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8238:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   8239:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   8240:            return 1;
                   8241:          }
                   8242:        }
                   8243:        if(lval <-1 || lval >1){
                   8244:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8245:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8246:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8247:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8248:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8249:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8250:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8251:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8252:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  8253:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8254:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8255:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8256:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8257:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8258:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8259:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8260:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8261:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  8262:          return 1;
                   8263:        }
                   8264:        cotvar[j][iv][i]=(double)(lval);
                   8265:        strcpy(line,stra);
1.223     brouard  8266:       }/* end loop ntv */
1.225     brouard  8267:       
1.223     brouard  8268:       /* Statuses  at wave */
1.137     brouard  8269:       cutv(stra, strb, line, ' '); 
1.223     brouard  8270:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  8271:        lval=-1;
1.136     brouard  8272:       }else{
1.238     brouard  8273:        errno=0;
                   8274:        lval=strtol(strb,&endptr,10); 
                   8275:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8276:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8277:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   8278:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   8279:          return 1;
                   8280:        }
1.136     brouard  8281:       }
1.225     brouard  8282:       
1.136     brouard  8283:       s[j][i]=lval;
1.225     brouard  8284:       
1.223     brouard  8285:       /* Date of Interview */
1.136     brouard  8286:       strcpy(line,stra);
                   8287:       cutv(stra, strb,line,' ');
1.169     brouard  8288:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8289:       }
1.169     brouard  8290:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  8291:        month=99;
                   8292:        year=9999;
1.136     brouard  8293:       }else{
1.225     brouard  8294:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   8295:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   8296:        return 1;
1.136     brouard  8297:       }
                   8298:       anint[j][i]= (double) year; 
                   8299:       mint[j][i]= (double)month; 
                   8300:       strcpy(line,stra);
1.223     brouard  8301:     } /* End loop on waves */
1.225     brouard  8302:     
1.223     brouard  8303:     /* Date of death */
1.136     brouard  8304:     cutv(stra, strb,line,' '); 
1.169     brouard  8305:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8306:     }
1.169     brouard  8307:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  8308:       month=99;
                   8309:       year=9999;
                   8310:     }else{
1.141     brouard  8311:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  8312:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   8313:       return 1;
1.136     brouard  8314:     }
                   8315:     andc[i]=(double) year; 
                   8316:     moisdc[i]=(double) month; 
                   8317:     strcpy(line,stra);
                   8318:     
1.223     brouard  8319:     /* Date of birth */
1.136     brouard  8320:     cutv(stra, strb,line,' '); 
1.169     brouard  8321:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8322:     }
1.169     brouard  8323:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  8324:       month=99;
                   8325:       year=9999;
                   8326:     }else{
1.141     brouard  8327:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   8328:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8329:       return 1;
1.136     brouard  8330:     }
                   8331:     if (year==9999) {
1.141     brouard  8332:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   8333:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8334:       return 1;
                   8335:       
1.136     brouard  8336:     }
                   8337:     annais[i]=(double)(year);
                   8338:     moisnais[i]=(double)(month); 
                   8339:     strcpy(line,stra);
1.225     brouard  8340:     
1.223     brouard  8341:     /* Sample weight */
1.136     brouard  8342:     cutv(stra, strb,line,' '); 
                   8343:     errno=0;
                   8344:     dval=strtod(strb,&endptr); 
                   8345:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  8346:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   8347:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  8348:       fflush(ficlog);
                   8349:       return 1;
                   8350:     }
                   8351:     weight[i]=dval; 
                   8352:     strcpy(line,stra);
1.225     brouard  8353:     
1.223     brouard  8354:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   8355:       cutv(stra, strb, line, ' '); 
                   8356:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  8357:        lval=-1;
1.223     brouard  8358:       }else{
1.225     brouard  8359:        errno=0;
                   8360:        /* what_kind_of_number(strb); */
                   8361:        dval=strtod(strb,&endptr);
                   8362:        /* if(strb != endptr && *endptr == '\0') */
                   8363:        /*   dval=dlval; */
                   8364:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8365:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8366:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   8367:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   8368:          return 1;
                   8369:        }
                   8370:        coqvar[iv][i]=dval; 
1.226     brouard  8371:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  8372:       }
                   8373:       strcpy(line,stra);
                   8374:     }/* end loop nqv */
1.136     brouard  8375:     
1.223     brouard  8376:     /* Covariate values */
1.136     brouard  8377:     for (j=ncovcol;j>=1;j--){
                   8378:       cutv(stra, strb,line,' '); 
1.223     brouard  8379:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  8380:        lval=-1;
1.136     brouard  8381:       }else{
1.225     brouard  8382:        errno=0;
                   8383:        lval=strtol(strb,&endptr,10); 
                   8384:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8385:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   8386:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   8387:          return 1;
                   8388:        }
1.136     brouard  8389:       }
                   8390:       if(lval <-1 || lval >1){
1.225     brouard  8391:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8392:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8393:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8394:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8395:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8396:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8397:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8398:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8399:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  8400:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8401:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8402:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8403:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8404:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8405:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8406:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8407:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8408:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  8409:        return 1;
1.136     brouard  8410:       }
                   8411:       covar[j][i]=(double)(lval);
                   8412:       strcpy(line,stra);
                   8413:     }  
                   8414:     lstra=strlen(stra);
1.225     brouard  8415:     
1.136     brouard  8416:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   8417:       stratrunc = &(stra[lstra-9]);
                   8418:       num[i]=atol(stratrunc);
                   8419:     }
                   8420:     else
                   8421:       num[i]=atol(stra);
                   8422:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   8423:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   8424:     
                   8425:     i=i+1;
                   8426:   } /* End loop reading  data */
1.225     brouard  8427:   
1.136     brouard  8428:   *imax=i-1; /* Number of individuals */
                   8429:   fclose(fic);
1.225     brouard  8430:   
1.136     brouard  8431:   return (0);
1.164     brouard  8432:   /* endread: */
1.225     brouard  8433:   printf("Exiting readdata: ");
                   8434:   fclose(fic);
                   8435:   return (1);
1.223     brouard  8436: }
1.126     brouard  8437: 
1.234     brouard  8438: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  8439:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  8440:   while (*p2 == ' ')
1.234     brouard  8441:     p2++; 
                   8442:   /* while ((*p1++ = *p2++) !=0) */
                   8443:   /*   ; */
                   8444:   /* do */
                   8445:   /*   while (*p2 == ' ') */
                   8446:   /*     p2++; */
                   8447:   /* while (*p1++ == *p2++); */
                   8448:   *stri=p2; 
1.145     brouard  8449: }
                   8450: 
1.235     brouard  8451: int decoderesult ( char resultline[], int nres)
1.230     brouard  8452: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   8453: {
1.235     brouard  8454:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  8455:   char resultsav[MAXLINE];
1.234     brouard  8456:   int resultmodel[MAXLINE];
                   8457:   int modelresult[MAXLINE];
1.230     brouard  8458:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   8459: 
1.234     brouard  8460:   removefirstspace(&resultline);
1.233     brouard  8461:   printf("decoderesult:%s\n",resultline);
1.230     brouard  8462: 
                   8463:   if (strstr(resultline,"v") !=0){
                   8464:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   8465:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   8466:     return 1;
                   8467:   }
                   8468:   trimbb(resultsav, resultline);
                   8469:   if (strlen(resultsav) >1){
                   8470:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   8471:   }
1.253     brouard  8472:   if(j == 0){ /* Resultline but no = */
                   8473:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   8474:     return (0);
                   8475:   }
                   8476:     
1.234     brouard  8477:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   8478:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8479:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8480:   }
                   8481:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   8482:     if(nbocc(resultsav,'=') >1){
                   8483:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   8484:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   8485:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   8486:     }else
                   8487:       cutl(strc,strd,resultsav,'=');
1.230     brouard  8488:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  8489:     
1.230     brouard  8490:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   8491:     Tvarsel[k]=atoi(strc);
                   8492:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   8493:     /* cptcovsel++;     */
                   8494:     if (nbocc(stra,'=') >0)
                   8495:       strcpy(resultsav,stra); /* and analyzes it */
                   8496:   }
1.235     brouard  8497:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  8498:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8499:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  8500:       match=0;
1.236     brouard  8501:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  8502:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  8503:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  8504:          match=1;
                   8505:          break;
                   8506:        }
                   8507:       }
                   8508:       if(match == 0){
                   8509:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8510:       }
                   8511:     }
                   8512:   }
1.235     brouard  8513:   /* Checking for missing or useless values in comparison of current model needs */
                   8514:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  8515:     match=0;
1.235     brouard  8516:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8517:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  8518:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  8519:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  8520:          ++match;
                   8521:        }
                   8522:       }
                   8523:     }
                   8524:     if(match == 0){
                   8525:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8526:     }else if(match > 1){
                   8527:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   8528:     }
                   8529:   }
1.235     brouard  8530:       
1.234     brouard  8531:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  8532:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8533:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   8534:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   8535:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   8536:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   8537:   /*    1 0 0 0 */
                   8538:   /*    2 1 0 0 */
                   8539:   /*    3 0 1 0 */ 
                   8540:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   8541:   /*    5 0 0 1 */
                   8542:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   8543:   /*    7 0 1 1 */
                   8544:   /*    8 1 1 1 */
1.237     brouard  8545:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   8546:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   8547:   /* V5*age V5 known which value for nres?  */
                   8548:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  8549:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   8550:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  8551:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  8552:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   8553:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  8554:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   8555:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   8556:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  8557:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   8558:       k4++;;
                   8559:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   8560:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   8561:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  8562:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   8563:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   8564:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  8565:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   8566:       k4q++;;
                   8567:     }
                   8568:   }
1.234     brouard  8569:   
1.235     brouard  8570:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  8571:   return (0);
                   8572: }
1.235     brouard  8573: 
1.230     brouard  8574: int decodemodel( char model[], int lastobs)
                   8575:  /**< This routine decodes the model and returns:
1.224     brouard  8576:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   8577:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   8578:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   8579:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   8580:        * - cptcovage number of covariates with age*products =2
                   8581:        * - cptcovs number of simple covariates
                   8582:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   8583:        *     which is a new column after the 9 (ncovcol) variables. 
                   8584:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   8585:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   8586:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   8587:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   8588:        */
1.136     brouard  8589: {
1.238     brouard  8590:   int i, j, k, ks, v;
1.227     brouard  8591:   int  j1, k1, k2, k3, k4;
1.136     brouard  8592:   char modelsav[80];
1.145     brouard  8593:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  8594:   char *strpt;
1.136     brouard  8595: 
1.145     brouard  8596:   /*removespace(model);*/
1.136     brouard  8597:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  8598:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  8599:     if (strstr(model,"AGE") !=0){
1.192     brouard  8600:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   8601:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  8602:       return 1;
                   8603:     }
1.141     brouard  8604:     if (strstr(model,"v") !=0){
                   8605:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   8606:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   8607:       return 1;
                   8608:     }
1.187     brouard  8609:     strcpy(modelsav,model); 
                   8610:     if ((strpt=strstr(model,"age*age")) !=0){
                   8611:       printf(" strpt=%s, model=%s\n",strpt, model);
                   8612:       if(strpt != model){
1.234     brouard  8613:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8614:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8615:  corresponding column of parameters.\n",model);
1.234     brouard  8616:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8617:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8618:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  8619:        return 1;
1.225     brouard  8620:       }
1.187     brouard  8621:       nagesqr=1;
                   8622:       if (strstr(model,"+age*age") !=0)
1.234     brouard  8623:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  8624:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  8625:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  8626:       else 
1.234     brouard  8627:        substrchaine(modelsav, model, "age*age");
1.187     brouard  8628:     }else
                   8629:       nagesqr=0;
                   8630:     if (strlen(modelsav) >1){
                   8631:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   8632:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  8633:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  8634:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  8635:                     * cst, age and age*age 
                   8636:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   8637:       /* including age products which are counted in cptcovage.
                   8638:        * but the covariates which are products must be treated 
                   8639:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  8640:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   8641:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  8642:       
                   8643:       
1.187     brouard  8644:       /*   Design
                   8645:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   8646:        *  <          ncovcol=8                >
                   8647:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   8648:        *   k=  1    2      3       4     5       6      7        8
                   8649:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   8650:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  8651:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   8652:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  8653:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   8654:        *  Tage[++cptcovage]=k
                   8655:        *       if products, new covar are created after ncovcol with k1
                   8656:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   8657:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   8658:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   8659:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   8660:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   8661:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   8662:        *  <          ncovcol=8                >
                   8663:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   8664:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   8665:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   8666:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8667:        * p Tprod[1]@2={                         6, 5}
                   8668:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   8669:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   8670:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   8671:        *How to reorganize?
                   8672:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   8673:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8674:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   8675:        * Struct []
                   8676:        */
1.225     brouard  8677:       
1.187     brouard  8678:       /* This loop fills the array Tvar from the string 'model'.*/
                   8679:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   8680:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   8681:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   8682:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   8683:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   8684:       /*       k=1 Tvar[1]=2 (from V2) */
                   8685:       /*       k=5 Tvar[5] */
                   8686:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  8687:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  8688:       /*       } */
1.198     brouard  8689:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  8690:       /*
                   8691:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  8692:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   8693:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   8694:       }
1.187     brouard  8695:       cptcovage=0;
                   8696:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  8697:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  8698:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  8699:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   8700:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   8701:        /*scanf("%d",i);*/
                   8702:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   8703:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   8704:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   8705:            /* covar is not filled and then is empty */
                   8706:            cptcovprod--;
                   8707:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   8708:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   8709:            Typevar[k]=1;  /* 1 for age product */
                   8710:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   8711:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   8712:            /*printf("stre=%s ", stre);*/
                   8713:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   8714:            cptcovprod--;
                   8715:            cutl(stre,strb,strc,'V');
                   8716:            Tvar[k]=atoi(stre);
                   8717:            Typevar[k]=1;  /* 1 for age product */
                   8718:            cptcovage++;
                   8719:            Tage[cptcovage]=k;
                   8720:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   8721:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   8722:            cptcovn++;
                   8723:            cptcovprodnoage++;k1++;
                   8724:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   8725:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   8726:                                                because this model-covariate is a construction we invent a new column
                   8727:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   8728:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   8729:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   8730:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   8731:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   8732:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   8733:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   8734:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   8735:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   8736:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   8737:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   8738:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  8739:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  8740:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   8741:            for (i=1; i<=lastobs;i++){
                   8742:              /* Computes the new covariate which is a product of
                   8743:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   8744:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   8745:            }
                   8746:          } /* End age is not in the model */
                   8747:        } /* End if model includes a product */
                   8748:        else { /* no more sum */
                   8749:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   8750:          /*  scanf("%d",i);*/
                   8751:          cutl(strd,strc,strb,'V');
                   8752:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   8753:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   8754:          Tvar[k]=atoi(strd);
                   8755:          Typevar[k]=0;  /* 0 for simple covariates */
                   8756:        }
                   8757:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  8758:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  8759:                                  scanf("%d",i);*/
1.187     brouard  8760:       } /* end of loop + on total covariates */
                   8761:     } /* end if strlen(modelsave == 0) age*age might exist */
                   8762:   } /* end if strlen(model == 0) */
1.136     brouard  8763:   
                   8764:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   8765:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  8766:   
1.136     brouard  8767:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  8768:      printf("cptcovprod=%d ", cptcovprod);
                   8769:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   8770:      scanf("%d ",i);*/
                   8771: 
                   8772: 
1.230     brouard  8773: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   8774:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  8775: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   8776:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   8777:    k =           1    2   3     4       5       6      7      8        9
                   8778:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   8779:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  8780:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   8781:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   8782:          Tmodelind[combination of covar]=k;
1.225     brouard  8783: */  
                   8784: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  8785:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  8786:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  8787:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  8788:   printf("Model=%s\n\
                   8789: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8790: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8791: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8792:   fprintf(ficlog,"Model=%s\n\
                   8793: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8794: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8795: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  8796:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  8797:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   8798:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  8799:       Fixed[k]= 0;
                   8800:       Dummy[k]= 0;
1.225     brouard  8801:       ncoveff++;
1.232     brouard  8802:       ncovf++;
1.234     brouard  8803:       nsd++;
                   8804:       modell[k].maintype= FTYPE;
                   8805:       TvarsD[nsd]=Tvar[k];
                   8806:       TvarsDind[nsd]=k;
                   8807:       TvarF[ncovf]=Tvar[k];
                   8808:       TvarFind[ncovf]=k;
                   8809:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8810:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8811:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   8812:       Fixed[k]= 0;
                   8813:       Dummy[k]= 0;
                   8814:       ncoveff++;
                   8815:       ncovf++;
                   8816:       modell[k].maintype= FTYPE;
                   8817:       TvarF[ncovf]=Tvar[k];
                   8818:       TvarFind[ncovf]=k;
1.230     brouard  8819:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  8820:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  8821:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  8822:       Fixed[k]= 0;
                   8823:       Dummy[k]= 1;
1.230     brouard  8824:       nqfveff++;
1.234     brouard  8825:       modell[k].maintype= FTYPE;
                   8826:       modell[k].subtype= FQ;
                   8827:       nsq++;
                   8828:       TvarsQ[nsq]=Tvar[k];
                   8829:       TvarsQind[nsq]=k;
1.232     brouard  8830:       ncovf++;
1.234     brouard  8831:       TvarF[ncovf]=Tvar[k];
                   8832:       TvarFind[ncovf]=k;
1.231     brouard  8833:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  8834:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  8835:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  8836:       Fixed[k]= 1;
                   8837:       Dummy[k]= 0;
1.225     brouard  8838:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  8839:       modell[k].maintype= VTYPE;
                   8840:       modell[k].subtype= VD;
                   8841:       nsd++;
                   8842:       TvarsD[nsd]=Tvar[k];
                   8843:       TvarsDind[nsd]=k;
                   8844:       ncovv++; /* Only simple time varying variables */
                   8845:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8846:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8847:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   8848:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  8849:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   8850:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  8851:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  8852:       Fixed[k]= 1;
                   8853:       Dummy[k]= 1;
                   8854:       nqtveff++;
                   8855:       modell[k].maintype= VTYPE;
                   8856:       modell[k].subtype= VQ;
                   8857:       ncovv++; /* Only simple time varying variables */
                   8858:       nsq++;
                   8859:       TvarsQ[nsq]=Tvar[k];
                   8860:       TvarsQind[nsq]=k;
                   8861:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8862:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8863:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   8864:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  8865:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   8866:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   8867:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  8868:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  8869:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  8870:       ncova++;
                   8871:       TvarA[ncova]=Tvar[k];
                   8872:       TvarAind[ncova]=k;
1.231     brouard  8873:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  8874:        Fixed[k]= 2;
                   8875:        Dummy[k]= 2;
                   8876:        modell[k].maintype= ATYPE;
                   8877:        modell[k].subtype= APFD;
                   8878:        /* ncoveff++; */
1.227     brouard  8879:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  8880:        Fixed[k]= 2;
                   8881:        Dummy[k]= 3;
                   8882:        modell[k].maintype= ATYPE;
                   8883:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   8884:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  8885:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  8886:        Fixed[k]= 3;
                   8887:        Dummy[k]= 2;
                   8888:        modell[k].maintype= ATYPE;
                   8889:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   8890:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  8891:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  8892:        Fixed[k]= 3;
                   8893:        Dummy[k]= 3;
                   8894:        modell[k].maintype= ATYPE;
                   8895:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   8896:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  8897:       }
                   8898:     }else if (Typevar[k] == 2) {  /* product without age */
                   8899:       k1=Tposprod[k];
                   8900:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  8901:        if(Tvard[k1][2] <=ncovcol){
                   8902:          Fixed[k]= 1;
                   8903:          Dummy[k]= 0;
                   8904:          modell[k].maintype= FTYPE;
                   8905:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   8906:          ncovf++; /* Fixed variables without age */
                   8907:          TvarF[ncovf]=Tvar[k];
                   8908:          TvarFind[ncovf]=k;
                   8909:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8910:          Fixed[k]= 0;  /* or 2 ?*/
                   8911:          Dummy[k]= 1;
                   8912:          modell[k].maintype= FTYPE;
                   8913:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   8914:          ncovf++; /* Varying variables without age */
                   8915:          TvarF[ncovf]=Tvar[k];
                   8916:          TvarFind[ncovf]=k;
                   8917:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8918:          Fixed[k]= 1;
                   8919:          Dummy[k]= 0;
                   8920:          modell[k].maintype= VTYPE;
                   8921:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   8922:          ncovv++; /* Varying variables without age */
                   8923:          TvarV[ncovv]=Tvar[k];
                   8924:          TvarVind[ncovv]=k;
                   8925:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8926:          Fixed[k]= 1;
                   8927:          Dummy[k]= 1;
                   8928:          modell[k].maintype= VTYPE;
                   8929:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   8930:          ncovv++; /* Varying variables without age */
                   8931:          TvarV[ncovv]=Tvar[k];
                   8932:          TvarVind[ncovv]=k;
                   8933:        }
1.227     brouard  8934:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  8935:        if(Tvard[k1][2] <=ncovcol){
                   8936:          Fixed[k]= 0;  /* or 2 ?*/
                   8937:          Dummy[k]= 1;
                   8938:          modell[k].maintype= FTYPE;
                   8939:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   8940:          ncovf++; /* Fixed variables without age */
                   8941:          TvarF[ncovf]=Tvar[k];
                   8942:          TvarFind[ncovf]=k;
                   8943:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8944:          Fixed[k]= 1;
                   8945:          Dummy[k]= 1;
                   8946:          modell[k].maintype= VTYPE;
                   8947:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   8948:          ncovv++; /* Varying variables without age */
                   8949:          TvarV[ncovv]=Tvar[k];
                   8950:          TvarVind[ncovv]=k;
                   8951:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8952:          Fixed[k]= 1;
                   8953:          Dummy[k]= 1;
                   8954:          modell[k].maintype= VTYPE;
                   8955:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   8956:          ncovv++; /* Varying variables without age */
                   8957:          TvarV[ncovv]=Tvar[k];
                   8958:          TvarVind[ncovv]=k;
                   8959:          ncovv++; /* Varying variables without age */
                   8960:          TvarV[ncovv]=Tvar[k];
                   8961:          TvarVind[ncovv]=k;
                   8962:        }
1.227     brouard  8963:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  8964:        if(Tvard[k1][2] <=ncovcol){
                   8965:          Fixed[k]= 1;
                   8966:          Dummy[k]= 1;
                   8967:          modell[k].maintype= VTYPE;
                   8968:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   8969:          ncovv++; /* Varying variables without age */
                   8970:          TvarV[ncovv]=Tvar[k];
                   8971:          TvarVind[ncovv]=k;
                   8972:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8973:          Fixed[k]= 1;
                   8974:          Dummy[k]= 1;
                   8975:          modell[k].maintype= VTYPE;
                   8976:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   8977:          ncovv++; /* Varying variables without age */
                   8978:          TvarV[ncovv]=Tvar[k];
                   8979:          TvarVind[ncovv]=k;
                   8980:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8981:          Fixed[k]= 1;
                   8982:          Dummy[k]= 0;
                   8983:          modell[k].maintype= VTYPE;
                   8984:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   8985:          ncovv++; /* Varying variables without age */
                   8986:          TvarV[ncovv]=Tvar[k];
                   8987:          TvarVind[ncovv]=k;
                   8988:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8989:          Fixed[k]= 1;
                   8990:          Dummy[k]= 1;
                   8991:          modell[k].maintype= VTYPE;
                   8992:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   8993:          ncovv++; /* Varying variables without age */
                   8994:          TvarV[ncovv]=Tvar[k];
                   8995:          TvarVind[ncovv]=k;
                   8996:        }
1.227     brouard  8997:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  8998:        if(Tvard[k1][2] <=ncovcol){
                   8999:          Fixed[k]= 1;
                   9000:          Dummy[k]= 1;
                   9001:          modell[k].maintype= VTYPE;
                   9002:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9003:          ncovv++; /* Varying variables without age */
                   9004:          TvarV[ncovv]=Tvar[k];
                   9005:          TvarVind[ncovv]=k;
                   9006:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9007:          Fixed[k]= 1;
                   9008:          Dummy[k]= 1;
                   9009:          modell[k].maintype= VTYPE;
                   9010:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9011:          ncovv++; /* Varying variables without age */
                   9012:          TvarV[ncovv]=Tvar[k];
                   9013:          TvarVind[ncovv]=k;
                   9014:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9015:          Fixed[k]= 1;
                   9016:          Dummy[k]= 1;
                   9017:          modell[k].maintype= VTYPE;
                   9018:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9019:          ncovv++; /* Varying variables without age */
                   9020:          TvarV[ncovv]=Tvar[k];
                   9021:          TvarVind[ncovv]=k;
                   9022:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9023:          Fixed[k]= 1;
                   9024:          Dummy[k]= 1;
                   9025:          modell[k].maintype= VTYPE;
                   9026:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9027:          ncovv++; /* Varying variables without age */
                   9028:          TvarV[ncovv]=Tvar[k];
                   9029:          TvarVind[ncovv]=k;
                   9030:        }
1.227     brouard  9031:       }else{
1.240     brouard  9032:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9033:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9034:       } /*end k1*/
1.225     brouard  9035:     }else{
1.226     brouard  9036:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9037:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9038:     }
1.227     brouard  9039:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9040:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9041:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9042:   }
                   9043:   /* Searching for doublons in the model */
                   9044:   for(k1=1; k1<= cptcovt;k1++){
                   9045:     for(k2=1; k2 <k1;k2++){
                   9046:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  9047:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9048:          if(Tvar[k1]==Tvar[k2]){
                   9049:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9050:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9051:            return(1);
                   9052:          }
                   9053:        }else if (Typevar[k1] ==2){
                   9054:          k3=Tposprod[k1];
                   9055:          k4=Tposprod[k2];
                   9056:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   9057:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9058:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9059:            return(1);
                   9060:          }
                   9061:        }
1.227     brouard  9062:       }
                   9063:     }
1.225     brouard  9064:   }
                   9065:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   9066:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  9067:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   9068:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  9069:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  9070:   /*endread:*/
1.225     brouard  9071:   printf("Exiting decodemodel: ");
                   9072:   return (1);
1.136     brouard  9073: }
                   9074: 
1.169     brouard  9075: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  9076: {/* Check ages at death */
1.136     brouard  9077:   int i, m;
1.218     brouard  9078:   int firstone=0;
                   9079:   
1.136     brouard  9080:   for (i=1; i<=imx; i++) {
                   9081:     for(m=2; (m<= maxwav); m++) {
                   9082:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   9083:        anint[m][i]=9999;
1.216     brouard  9084:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   9085:          s[m][i]=-1;
1.136     brouard  9086:       }
                   9087:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.169     brouard  9088:        *nberr = *nberr + 1;
1.218     brouard  9089:        if(firstone == 0){
                   9090:          firstone=1;
                   9091:        printf("Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\nOther similar cases in log file\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
                   9092:        }
                   9093:        fprintf(ficlog,"Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
1.136     brouard  9094:        s[m][i]=-1;
                   9095:       }
                   9096:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  9097:        (*nberr)++;
1.136     brouard  9098:        printf("Error! Month of death of individual %ld on line %d was unknown %2d, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,(int)moisdc[i]); 
                   9099:        fprintf(ficlog,"Error! Month of death of individual %ld on line %d was unknown %f, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,moisdc[i]); 
                   9100:        s[m][i]=-1; /* We prefer to skip it (and to skip it in version 0.8a1 too */
                   9101:       }
                   9102:     }
                   9103:   }
                   9104: 
                   9105:   for (i=1; i<=imx; i++)  {
                   9106:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   9107:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  9108:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  9109:        if (s[m][i] >= nlstate+1) {
1.169     brouard  9110:          if(agedc[i]>0){
                   9111:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  9112:              agev[m][i]=agedc[i];
1.214     brouard  9113:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  9114:            }else {
1.136     brouard  9115:              if ((int)andc[i]!=9999){
                   9116:                nbwarn++;
                   9117:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   9118:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   9119:                agev[m][i]=-1;
                   9120:              }
                   9121:            }
1.169     brouard  9122:          } /* agedc > 0 */
1.214     brouard  9123:        } /* end if */
1.136     brouard  9124:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   9125:                                 years but with the precision of a month */
                   9126:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   9127:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   9128:            agev[m][i]=1;
                   9129:          else if(agev[m][i] < *agemin){ 
                   9130:            *agemin=agev[m][i];
                   9131:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   9132:          }
                   9133:          else if(agev[m][i] >*agemax){
                   9134:            *agemax=agev[m][i];
1.156     brouard  9135:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  9136:          }
                   9137:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   9138:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  9139:        } /* en if 9*/
1.136     brouard  9140:        else { /* =9 */
1.214     brouard  9141:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  9142:          agev[m][i]=1;
                   9143:          s[m][i]=-1;
                   9144:        }
                   9145:       }
1.214     brouard  9146:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  9147:        agev[m][i]=1;
1.214     brouard  9148:       else{
                   9149:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9150:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9151:        agev[m][i]=0;
                   9152:       }
                   9153:     } /* End for lastpass */
                   9154:   }
1.136     brouard  9155:     
                   9156:   for (i=1; i<=imx; i++)  {
                   9157:     for(m=firstpass; (m<=lastpass); m++){
                   9158:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  9159:        (*nberr)++;
1.136     brouard  9160:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9161:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9162:        return 1;
                   9163:       }
                   9164:     }
                   9165:   }
                   9166: 
                   9167:   /*for (i=1; i<=imx; i++){
                   9168:   for (m=firstpass; (m<lastpass); m++){
                   9169:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   9170: }
                   9171: 
                   9172: }*/
                   9173: 
                   9174: 
1.139     brouard  9175:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   9176:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  9177: 
                   9178:   return (0);
1.164     brouard  9179:  /* endread:*/
1.136     brouard  9180:     printf("Exiting calandcheckages: ");
                   9181:     return (1);
                   9182: }
                   9183: 
1.172     brouard  9184: #if defined(_MSC_VER)
                   9185: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9186: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9187: //#include "stdafx.h"
                   9188: //#include <stdio.h>
                   9189: //#include <tchar.h>
                   9190: //#include <windows.h>
                   9191: //#include <iostream>
                   9192: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   9193: 
                   9194: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9195: 
                   9196: BOOL IsWow64()
                   9197: {
                   9198:        BOOL bIsWow64 = FALSE;
                   9199: 
                   9200:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   9201:        //  (HANDLE, PBOOL);
                   9202: 
                   9203:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9204: 
                   9205:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   9206:        const char funcName[] = "IsWow64Process";
                   9207:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   9208:                GetProcAddress(module, funcName);
                   9209: 
                   9210:        if (NULL != fnIsWow64Process)
                   9211:        {
                   9212:                if (!fnIsWow64Process(GetCurrentProcess(),
                   9213:                        &bIsWow64))
                   9214:                        //throw std::exception("Unknown error");
                   9215:                        printf("Unknown error\n");
                   9216:        }
                   9217:        return bIsWow64 != FALSE;
                   9218: }
                   9219: #endif
1.177     brouard  9220: 
1.191     brouard  9221: void syscompilerinfo(int logged)
1.167     brouard  9222:  {
                   9223:    /* #include "syscompilerinfo.h"*/
1.185     brouard  9224:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   9225:    /* /GS /W3 /Gy
                   9226:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   9227:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   9228:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  9229:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   9230:    */ 
                   9231:    /* 64 bits */
1.185     brouard  9232:    /*
                   9233:      /GS /W3 /Gy
                   9234:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   9235:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   9236:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   9237:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   9238:    /* Optimization are useless and O3 is slower than O2 */
                   9239:    /*
                   9240:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   9241:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   9242:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   9243:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   9244:    */
1.186     brouard  9245:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  9246:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   9247:       /PDB:"visual studio
                   9248:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   9249:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   9250:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   9251:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   9252:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   9253:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   9254:       uiAccess='false'"
                   9255:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   9256:       /NOLOGO /TLBID:1
                   9257:    */
1.177     brouard  9258: #if defined __INTEL_COMPILER
1.178     brouard  9259: #if defined(__GNUC__)
                   9260:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   9261: #endif
1.177     brouard  9262: #elif defined(__GNUC__) 
1.179     brouard  9263: #ifndef  __APPLE__
1.174     brouard  9264: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  9265: #endif
1.177     brouard  9266:    struct utsname sysInfo;
1.178     brouard  9267:    int cross = CROSS;
                   9268:    if (cross){
                   9269:           printf("Cross-");
1.191     brouard  9270:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  9271:    }
1.174     brouard  9272: #endif
                   9273: 
1.171     brouard  9274: #include <stdint.h>
1.178     brouard  9275: 
1.191     brouard  9276:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  9277: #if defined(__clang__)
1.191     brouard  9278:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  9279: #endif
                   9280: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  9281:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  9282: #endif
                   9283: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  9284:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  9285: #endif
                   9286: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  9287:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  9288: #endif
                   9289: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  9290:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  9291: #endif
                   9292: #if defined(_MSC_VER)
1.191     brouard  9293:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  9294: #endif
                   9295: #if defined(__PGI)
1.191     brouard  9296:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  9297: #endif
                   9298: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  9299:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  9300: #endif
1.191     brouard  9301:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  9302:    
1.167     brouard  9303: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   9304: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   9305:     // Windows (x64 and x86)
1.191     brouard  9306:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  9307: #elif __unix__ // all unices, not all compilers
                   9308:     // Unix
1.191     brouard  9309:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  9310: #elif __linux__
                   9311:     // linux
1.191     brouard  9312:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  9313: #elif __APPLE__
1.174     brouard  9314:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  9315:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  9316: #endif
                   9317: 
                   9318: /*  __MINGW32__          */
                   9319: /*  __CYGWIN__  */
                   9320: /* __MINGW64__  */
                   9321: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   9322: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   9323: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   9324: /* _WIN64  // Defined for applications for Win64. */
                   9325: /* _M_X64 // Defined for compilations that target x64 processors. */
                   9326: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  9327: 
1.167     brouard  9328: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  9329:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  9330: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  9331:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  9332: #else
1.191     brouard  9333:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  9334: #endif
                   9335: 
1.169     brouard  9336: #if defined(__GNUC__)
                   9337: # if defined(__GNUC_PATCHLEVEL__)
                   9338: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9339:                             + __GNUC_MINOR__ * 100 \
                   9340:                             + __GNUC_PATCHLEVEL__)
                   9341: # else
                   9342: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9343:                             + __GNUC_MINOR__ * 100)
                   9344: # endif
1.174     brouard  9345:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  9346:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  9347: 
                   9348:    if (uname(&sysInfo) != -1) {
                   9349:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  9350:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  9351:    }
                   9352:    else
                   9353:       perror("uname() error");
1.179     brouard  9354:    //#ifndef __INTEL_COMPILER 
                   9355: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  9356:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  9357:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  9358: #endif
1.169     brouard  9359: #endif
1.172     brouard  9360: 
                   9361:    //   void main()
                   9362:    //   {
1.169     brouard  9363: #if defined(_MSC_VER)
1.174     brouard  9364:    if (IsWow64()){
1.191     brouard  9365:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   9366:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  9367:    }
                   9368:    else{
1.191     brouard  9369:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   9370:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  9371:    }
1.172     brouard  9372:    //     printf("\nPress Enter to continue...");
                   9373:    //     getchar();
                   9374:    //   }
                   9375: 
1.169     brouard  9376: #endif
                   9377:    
1.167     brouard  9378: 
1.219     brouard  9379: }
1.136     brouard  9380: 
1.219     brouard  9381: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  9382:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  9383:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  9384:   /* double ftolpl = 1.e-10; */
1.180     brouard  9385:   double age, agebase, agelim;
1.203     brouard  9386:   double tot;
1.180     brouard  9387: 
1.202     brouard  9388:   strcpy(filerespl,"PL_");
                   9389:   strcat(filerespl,fileresu);
                   9390:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   9391:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9392:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9393:   }
1.227     brouard  9394:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   9395:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  9396:   pstamp(ficrespl);
1.203     brouard  9397:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  9398:   fprintf(ficrespl,"#Age ");
                   9399:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   9400:   fprintf(ficrespl,"\n");
1.180     brouard  9401:   
1.219     brouard  9402:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  9403: 
1.219     brouard  9404:   agebase=ageminpar;
                   9405:   agelim=agemaxpar;
1.180     brouard  9406: 
1.227     brouard  9407:   /* i1=pow(2,ncoveff); */
1.234     brouard  9408:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  9409:   if (cptcovn < 1){i1=1;}
1.180     brouard  9410: 
1.238     brouard  9411:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   9412:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  9413:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9414:        continue;
1.235     brouard  9415: 
1.238     brouard  9416:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9417:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   9418:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   9419:       /* k=k+1; */
                   9420:       /* to clean */
                   9421:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9422:       fprintf(ficrespl,"#******");
                   9423:       printf("#******");
                   9424:       fprintf(ficlog,"#******");
                   9425:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9426:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   9427:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9428:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9429:       }
                   9430:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9431:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9432:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9433:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9434:       }
                   9435:       fprintf(ficrespl,"******\n");
                   9436:       printf("******\n");
                   9437:       fprintf(ficlog,"******\n");
                   9438:       if(invalidvarcomb[k]){
                   9439:        printf("\nCombination (%d) ignored because no case \n",k); 
                   9440:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   9441:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   9442:        continue;
                   9443:       }
1.219     brouard  9444: 
1.238     brouard  9445:       fprintf(ficrespl,"#Age ");
                   9446:       for(j=1;j<=cptcoveff;j++) {
                   9447:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9448:       }
                   9449:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   9450:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  9451:     
1.238     brouard  9452:       for (age=agebase; age<=agelim; age++){
                   9453:        /* for (age=agebase; age<=agebase; age++){ */
                   9454:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   9455:        fprintf(ficrespl,"%.0f ",age );
                   9456:        for(j=1;j<=cptcoveff;j++)
                   9457:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9458:        tot=0.;
                   9459:        for(i=1; i<=nlstate;i++){
                   9460:          tot +=  prlim[i][i];
                   9461:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   9462:        }
                   9463:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   9464:       } /* Age */
                   9465:       /* was end of cptcod */
                   9466:     } /* cptcov */
                   9467:   } /* nres */
1.219     brouard  9468:   return 0;
1.180     brouard  9469: }
                   9470: 
1.218     brouard  9471: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   9472:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   9473:        
                   9474:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   9475:    * at any age between ageminpar and agemaxpar
                   9476:         */
1.235     brouard  9477:   int i, j, k, i1, nres=0 ;
1.217     brouard  9478:   /* double ftolpl = 1.e-10; */
                   9479:   double age, agebase, agelim;
                   9480:   double tot;
1.218     brouard  9481:   /* double ***mobaverage; */
                   9482:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  9483: 
                   9484:   strcpy(fileresplb,"PLB_");
                   9485:   strcat(fileresplb,fileresu);
                   9486:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   9487:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9488:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9489:   }
                   9490:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9491:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9492:   pstamp(ficresplb);
                   9493:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   9494:   fprintf(ficresplb,"#Age ");
                   9495:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   9496:   fprintf(ficresplb,"\n");
                   9497:   
1.218     brouard  9498:   
                   9499:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   9500:   
                   9501:   agebase=ageminpar;
                   9502:   agelim=agemaxpar;
                   9503:   
                   9504:   
1.227     brouard  9505:   i1=pow(2,cptcoveff);
1.218     brouard  9506:   if (cptcovn < 1){i1=1;}
1.227     brouard  9507:   
1.238     brouard  9508:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9509:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  9510:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9511:        continue;
                   9512:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9513:       fprintf(ficresplb,"#******");
                   9514:       printf("#******");
                   9515:       fprintf(ficlog,"#******");
                   9516:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9517:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9518:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9519:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9520:       }
                   9521:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9522:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9523:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9524:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9525:       }
                   9526:       fprintf(ficresplb,"******\n");
                   9527:       printf("******\n");
                   9528:       fprintf(ficlog,"******\n");
                   9529:       if(invalidvarcomb[k]){
                   9530:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   9531:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   9532:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   9533:        continue;
                   9534:       }
1.218     brouard  9535:     
1.238     brouard  9536:       fprintf(ficresplb,"#Age ");
                   9537:       for(j=1;j<=cptcoveff;j++) {
                   9538:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9539:       }
                   9540:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   9541:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  9542:     
                   9543:     
1.238     brouard  9544:       for (age=agebase; age<=agelim; age++){
                   9545:        /* for (age=agebase; age<=agebase; age++){ */
                   9546:        if(mobilavproj > 0){
                   9547:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   9548:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9549:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  9550:        }else if (mobilavproj == 0){
                   9551:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9552:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9553:          exit(1);
                   9554:        }else{
                   9555:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9556:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.238     brouard  9557:        }
                   9558:        fprintf(ficresplb,"%.0f ",age );
                   9559:        for(j=1;j<=cptcoveff;j++)
                   9560:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9561:        tot=0.;
                   9562:        for(i=1; i<=nlstate;i++){
                   9563:          tot +=  bprlim[i][i];
                   9564:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   9565:        }
                   9566:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   9567:       } /* Age */
                   9568:       /* was end of cptcod */
1.255   ! brouard  9569:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  9570:     } /* end of any combination */
                   9571:   } /* end of nres */  
1.218     brouard  9572:   /* hBijx(p, bage, fage); */
                   9573:   /* fclose(ficrespijb); */
                   9574:   
                   9575:   return 0;
1.217     brouard  9576: }
1.218     brouard  9577:  
1.180     brouard  9578: int hPijx(double *p, int bage, int fage){
                   9579:     /*------------- h Pij x at various ages ------------*/
                   9580: 
                   9581:   int stepsize;
                   9582:   int agelim;
                   9583:   int hstepm;
                   9584:   int nhstepm;
1.235     brouard  9585:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  9586: 
                   9587:   double agedeb;
                   9588:   double ***p3mat;
                   9589: 
1.201     brouard  9590:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  9591:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   9592:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9593:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9594:     }
                   9595:     printf("Computing pij: result on file '%s' \n", filerespij);
                   9596:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   9597:   
                   9598:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9599:     /*if (stepm<=24) stepsize=2;*/
                   9600: 
                   9601:     agelim=AGESUP;
                   9602:     hstepm=stepsize*YEARM; /* Every year of age */
                   9603:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  9604:                
1.180     brouard  9605:     /* hstepm=1;   aff par mois*/
                   9606:     pstamp(ficrespij);
                   9607:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  9608:     i1= pow(2,cptcoveff);
1.218     brouard  9609:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9610:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9611:                /*      k=k+1;  */
1.235     brouard  9612:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9613:     for(k=1; k<=i1;k++){
1.253     brouard  9614:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  9615:        continue;
1.183     brouard  9616:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  9617:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  9618:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  9619:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9620:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9621:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9622:       }
1.183     brouard  9623:       fprintf(ficrespij,"******\n");
                   9624:       
                   9625:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   9626:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   9627:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   9628:        
                   9629:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  9630:        
1.183     brouard  9631:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9632:        oldm=oldms;savm=savms;
1.235     brouard  9633:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  9634:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   9635:        for(i=1; i<=nlstate;i++)
                   9636:          for(j=1; j<=nlstate+ndeath;j++)
                   9637:            fprintf(ficrespij," %1d-%1d",i,j);
                   9638:        fprintf(ficrespij,"\n");
                   9639:        for (h=0; h<=nhstepm; h++){
                   9640:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9641:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  9642:          for(i=1; i<=nlstate;i++)
                   9643:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  9644:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  9645:          fprintf(ficrespij,"\n");
                   9646:        }
1.183     brouard  9647:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9648:        fprintf(ficrespij,"\n");
                   9649:       }
1.180     brouard  9650:       /*}*/
                   9651:     }
1.218     brouard  9652:     return 0;
1.180     brouard  9653: }
1.218     brouard  9654:  
                   9655:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  9656:     /*------------- h Bij x at various ages ------------*/
                   9657: 
                   9658:   int stepsize;
1.218     brouard  9659:   /* int agelim; */
                   9660:        int ageminl;
1.217     brouard  9661:   int hstepm;
                   9662:   int nhstepm;
1.238     brouard  9663:   int h, i, i1, j, k, nres;
1.218     brouard  9664:        
1.217     brouard  9665:   double agedeb;
                   9666:   double ***p3mat;
1.218     brouard  9667:        
                   9668:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   9669:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   9670:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9671:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9672:   }
                   9673:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   9674:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   9675:   
                   9676:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9677:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  9678:   
1.218     brouard  9679:   /* agelim=AGESUP; */
                   9680:   ageminl=30;
                   9681:   hstepm=stepsize*YEARM; /* Every year of age */
                   9682:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   9683:   
                   9684:   /* hstepm=1;   aff par mois*/
                   9685:   pstamp(ficrespijb);
1.255   ! brouard  9686:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  9687:   i1= pow(2,cptcoveff);
1.218     brouard  9688:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9689:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9690:   /*   k=k+1;  */
1.238     brouard  9691:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9692:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  9693:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9694:        continue;
                   9695:       fprintf(ficrespijb,"\n#****** ");
                   9696:       for(j=1;j<=cptcoveff;j++)
                   9697:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9698:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9699:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9700:       }
                   9701:       fprintf(ficrespijb,"******\n");
                   9702:       if(invalidvarcomb[k]){
                   9703:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   9704:        continue;
                   9705:       }
                   9706:       
                   9707:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   9708:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   9709:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   9710:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   9711:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   9712:        
                   9713:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   9714:        
                   9715:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9716:        /* oldm=oldms;savm=savms; */
                   9717:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9718:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k);
                   9719:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255   ! brouard  9720:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  9721:        for(i=1; i<=nlstate;i++)
                   9722:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  9723:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  9724:        fprintf(ficrespijb,"\n");
1.238     brouard  9725:        for (h=0; h<=nhstepm; h++){
                   9726:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9727:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   9728:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   9729:          for(i=1; i<=nlstate;i++)
                   9730:            for(j=1; j<=nlstate+ndeath;j++)
                   9731:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   9732:          fprintf(ficrespijb,"\n");
                   9733:        }
                   9734:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9735:        fprintf(ficrespijb,"\n");
                   9736:       } /* end age deb */
                   9737:     } /* end combination */
                   9738:   } /* end nres */
1.218     brouard  9739:   return 0;
                   9740:  } /*  hBijx */
1.217     brouard  9741: 
1.180     brouard  9742: 
1.136     brouard  9743: /***********************************************/
                   9744: /**************** Main Program *****************/
                   9745: /***********************************************/
                   9746: 
                   9747: int main(int argc, char *argv[])
                   9748: {
                   9749: #ifdef GSL
                   9750:   const gsl_multimin_fminimizer_type *T;
                   9751:   size_t iteri = 0, it;
                   9752:   int rval = GSL_CONTINUE;
                   9753:   int status = GSL_SUCCESS;
                   9754:   double ssval;
                   9755: #endif
                   9756:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  9757:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  9758:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  9759:   int jj, ll, li, lj, lk;
1.136     brouard  9760:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  9761:   int num_filled;
1.136     brouard  9762:   int itimes;
                   9763:   int NDIM=2;
                   9764:   int vpopbased=0;
1.235     brouard  9765:   int nres=0;
1.136     brouard  9766: 
1.164     brouard  9767:   char ca[32], cb[32];
1.136     brouard  9768:   /*  FILE *fichtm; *//* Html File */
                   9769:   /* FILE *ficgp;*/ /*Gnuplot File */
                   9770:   struct stat info;
1.191     brouard  9771:   double agedeb=0.;
1.194     brouard  9772: 
                   9773:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  9774:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  9775: 
1.165     brouard  9776:   double fret;
1.191     brouard  9777:   double dum=0.; /* Dummy variable */
1.136     brouard  9778:   double ***p3mat;
1.218     brouard  9779:   /* double ***mobaverage; */
1.164     brouard  9780: 
                   9781:   char line[MAXLINE];
1.197     brouard  9782:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   9783: 
1.234     brouard  9784:   char  modeltemp[MAXLINE];
1.230     brouard  9785:   char resultline[MAXLINE];
                   9786:   
1.136     brouard  9787:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  9788:   char *tok, *val; /* pathtot */
1.136     brouard  9789:   int firstobs=1, lastobs=10;
1.195     brouard  9790:   int c,  h , cpt, c2;
1.191     brouard  9791:   int jl=0;
                   9792:   int i1, j1, jk, stepsize=0;
1.194     brouard  9793:   int count=0;
                   9794: 
1.164     brouard  9795:   int *tab; 
1.136     brouard  9796:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  9797:   int backcast=0;
1.136     brouard  9798:   int mobilav=0,popforecast=0;
1.191     brouard  9799:   int hstepm=0, nhstepm=0;
1.136     brouard  9800:   int agemortsup;
                   9801:   float  sumlpop=0.;
                   9802:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   9803:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   9804: 
1.191     brouard  9805:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  9806:   double ftolpl=FTOL;
                   9807:   double **prlim;
1.217     brouard  9808:   double **bprlim;
1.136     brouard  9809:   double ***param; /* Matrix of parameters */
1.251     brouard  9810:   double ***paramstart; /* Matrix of starting parameter values */
                   9811:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  9812:   double **matcov; /* Matrix of covariance */
1.203     brouard  9813:   double **hess; /* Hessian matrix */
1.136     brouard  9814:   double ***delti3; /* Scale */
                   9815:   double *delti; /* Scale */
                   9816:   double ***eij, ***vareij;
                   9817:   double **varpl; /* Variances of prevalence limits by age */
                   9818:   double *epj, vepp;
1.164     brouard  9819: 
1.136     brouard  9820:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  9821:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   9822: 
1.136     brouard  9823:   double **ximort;
1.145     brouard  9824:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  9825:   int *dcwave;
                   9826: 
1.164     brouard  9827:   char z[1]="c";
1.136     brouard  9828: 
                   9829:   /*char  *strt;*/
                   9830:   char strtend[80];
1.126     brouard  9831: 
1.164     brouard  9832: 
1.126     brouard  9833: /*   setlocale (LC_ALL, ""); */
                   9834: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   9835: /*   textdomain (PACKAGE); */
                   9836: /*   setlocale (LC_CTYPE, ""); */
                   9837: /*   setlocale (LC_MESSAGES, ""); */
                   9838: 
                   9839:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  9840:   rstart_time = time(NULL);  
                   9841:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   9842:   start_time = *localtime(&rstart_time);
1.126     brouard  9843:   curr_time=start_time;
1.157     brouard  9844:   /*tml = *localtime(&start_time.tm_sec);*/
                   9845:   /* strcpy(strstart,asctime(&tml)); */
                   9846:   strcpy(strstart,asctime(&start_time));
1.126     brouard  9847: 
                   9848: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  9849: /*  tp.tm_sec = tp.tm_sec +86400; */
                   9850: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  9851: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   9852: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   9853: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  9854: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  9855: /*   strt=asctime(&tmg); */
                   9856: /*   printf("Time(after) =%s",strstart);  */
                   9857: /*  (void) time (&time_value);
                   9858: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   9859: *  tm = *localtime(&time_value);
                   9860: *  strstart=asctime(&tm);
                   9861: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   9862: */
                   9863: 
                   9864:   nberr=0; /* Number of errors and warnings */
                   9865:   nbwarn=0;
1.184     brouard  9866: #ifdef WIN32
                   9867:   _getcwd(pathcd, size);
                   9868: #else
1.126     brouard  9869:   getcwd(pathcd, size);
1.184     brouard  9870: #endif
1.191     brouard  9871:   syscompilerinfo(0);
1.196     brouard  9872:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  9873:   if(argc <=1){
                   9874:     printf("\nEnter the parameter file name: ");
1.205     brouard  9875:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   9876:       printf("ERROR Empty parameter file name\n");
                   9877:       goto end;
                   9878:     }
1.126     brouard  9879:     i=strlen(pathr);
                   9880:     if(pathr[i-1]=='\n')
                   9881:       pathr[i-1]='\0';
1.156     brouard  9882:     i=strlen(pathr);
1.205     brouard  9883:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  9884:       pathr[i-1]='\0';
1.205     brouard  9885:     }
                   9886:     i=strlen(pathr);
                   9887:     if( i==0 ){
                   9888:       printf("ERROR Empty parameter file name\n");
                   9889:       goto end;
                   9890:     }
                   9891:     for (tok = pathr; tok != NULL; ){
1.126     brouard  9892:       printf("Pathr |%s|\n",pathr);
                   9893:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   9894:       printf("val= |%s| pathr=%s\n",val,pathr);
                   9895:       strcpy (pathtot, val);
                   9896:       if(pathr[0] == '\0') break; /* Dirty */
                   9897:     }
                   9898:   }
                   9899:   else{
                   9900:     strcpy(pathtot,argv[1]);
                   9901:   }
                   9902:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   9903:   /*cygwin_split_path(pathtot,path,optionfile);
                   9904:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   9905:   /* cutv(path,optionfile,pathtot,'\\');*/
                   9906: 
                   9907:   /* Split argv[0], imach program to get pathimach */
                   9908:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   9909:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9910:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9911:  /*   strcpy(pathimach,argv[0]); */
                   9912:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   9913:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   9914:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  9915: #ifdef WIN32
                   9916:   _chdir(path); /* Can be a relative path */
                   9917:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   9918: #else
1.126     brouard  9919:   chdir(path); /* Can be a relative path */
1.184     brouard  9920:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   9921: #endif
                   9922:   printf("Current directory %s!\n",pathcd);
1.126     brouard  9923:   strcpy(command,"mkdir ");
                   9924:   strcat(command,optionfilefiname);
                   9925:   if((outcmd=system(command)) != 0){
1.169     brouard  9926:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  9927:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   9928:     /* fclose(ficlog); */
                   9929: /*     exit(1); */
                   9930:   }
                   9931: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   9932: /*     perror("mkdir"); */
                   9933: /*   } */
                   9934: 
                   9935:   /*-------- arguments in the command line --------*/
                   9936: 
1.186     brouard  9937:   /* Main Log file */
1.126     brouard  9938:   strcat(filelog, optionfilefiname);
                   9939:   strcat(filelog,".log");    /* */
                   9940:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   9941:     printf("Problem with logfile %s\n",filelog);
                   9942:     goto end;
                   9943:   }
                   9944:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  9945:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  9946:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   9947:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   9948:  path=%s \n\
                   9949:  optionfile=%s\n\
                   9950:  optionfilext=%s\n\
1.156     brouard  9951:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  9952: 
1.197     brouard  9953:   syscompilerinfo(1);
1.167     brouard  9954: 
1.126     brouard  9955:   printf("Local time (at start):%s",strstart);
                   9956:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   9957:   fflush(ficlog);
                   9958: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  9959: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  9960: 
                   9961:   /* */
                   9962:   strcpy(fileres,"r");
                   9963:   strcat(fileres, optionfilefiname);
1.201     brouard  9964:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  9965:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  9966:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  9967: 
1.186     brouard  9968:   /* Main ---------arguments file --------*/
1.126     brouard  9969: 
                   9970:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  9971:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   9972:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  9973:     fflush(ficlog);
1.149     brouard  9974:     /* goto end; */
                   9975:     exit(70); 
1.126     brouard  9976:   }
                   9977: 
                   9978: 
                   9979: 
                   9980:   strcpy(filereso,"o");
1.201     brouard  9981:   strcat(filereso,fileresu);
1.126     brouard  9982:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   9983:     printf("Problem with Output resultfile: %s\n", filereso);
                   9984:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   9985:     fflush(ficlog);
                   9986:     goto end;
                   9987:   }
                   9988: 
                   9989:   /* Reads comments: lines beginning with '#' */
                   9990:   numlinepar=0;
1.197     brouard  9991: 
                   9992:     /* First parameter line */
                   9993:   while(fgets(line, MAXLINE, ficpar)) {
                   9994:     /* If line starts with a # it is a comment */
                   9995:     if (line[0] == '#') {
                   9996:       numlinepar++;
                   9997:       fputs(line,stdout);
                   9998:       fputs(line,ficparo);
                   9999:       fputs(line,ficlog);
                   10000:       continue;
                   10001:     }else
                   10002:       break;
                   10003:   }
                   10004:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   10005:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   10006:     if (num_filled != 5) {
                   10007:       printf("Should be 5 parameters\n");
                   10008:     }
1.126     brouard  10009:     numlinepar++;
1.197     brouard  10010:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   10011:   }
                   10012:   /* Second parameter line */
                   10013:   while(fgets(line, MAXLINE, ficpar)) {
                   10014:     /* If line starts with a # it is a comment */
                   10015:     if (line[0] == '#') {
                   10016:       numlinepar++;
                   10017:       fputs(line,stdout);
                   10018:       fputs(line,ficparo);
                   10019:       fputs(line,ficlog);
                   10020:       continue;
                   10021:     }else
                   10022:       break;
                   10023:   }
1.223     brouard  10024:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   10025:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   10026:     if (num_filled != 11) {
                   10027:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  10028:       printf("but line=%s\n",line);
1.197     brouard  10029:     }
1.223     brouard  10030:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  10031:   }
1.203     brouard  10032:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  10033:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  10034:   /* Third parameter line */
                   10035:   while(fgets(line, MAXLINE, ficpar)) {
                   10036:     /* If line starts with a # it is a comment */
                   10037:     if (line[0] == '#') {
                   10038:       numlinepar++;
                   10039:       fputs(line,stdout);
                   10040:       fputs(line,ficparo);
                   10041:       fputs(line,ficlog);
                   10042:       continue;
                   10043:     }else
                   10044:       break;
                   10045:   }
1.201     brouard  10046:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
                   10047:     if (num_filled == 0)
                   10048:             model[0]='\0';
                   10049:     else if (num_filled != 1){
1.197     brouard  10050:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10051:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10052:       model[0]='\0';
                   10053:       goto end;
                   10054:     }
                   10055:     else{
                   10056:       if (model[0]=='+'){
                   10057:        for(i=1; i<=strlen(model);i++)
                   10058:          modeltemp[i-1]=model[i];
1.201     brouard  10059:        strcpy(model,modeltemp); 
1.197     brouard  10060:       }
                   10061:     }
1.199     brouard  10062:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  10063:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  10064:   }
                   10065:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   10066:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   10067:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  10068:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   10069:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  10070:   fflush(ficlog);
1.190     brouard  10071:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   10072:   if(model[0]=='#'){
1.187     brouard  10073:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   10074:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   10075:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   10076:     if(mle != -1){
                   10077:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   10078:       exit(1);
                   10079:     }
                   10080:   }
1.126     brouard  10081:   while((c=getc(ficpar))=='#' && c!= EOF){
                   10082:     ungetc(c,ficpar);
                   10083:     fgets(line, MAXLINE, ficpar);
                   10084:     numlinepar++;
1.195     brouard  10085:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   10086:       z[0]=line[1];
                   10087:     }
                   10088:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  10089:     fputs(line, stdout);
                   10090:     //puts(line);
1.126     brouard  10091:     fputs(line,ficparo);
                   10092:     fputs(line,ficlog);
                   10093:   }
                   10094:   ungetc(c,ficpar);
                   10095: 
                   10096:    
1.145     brouard  10097:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.225     brouard  10098:   coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
1.233     brouard  10099:   cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.225     brouard  10100:   cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
1.136     brouard  10101:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   10102:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   10103:      v1+v2*age+v2*v3 makes cptcovn = 3
                   10104:   */
                   10105:   if (strlen(model)>1) 
1.187     brouard  10106:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  10107:   else
1.187     brouard  10108:     ncovmodel=2; /* Constant and age */
1.133     brouard  10109:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   10110:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  10111:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   10112:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10113:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10114:     fflush(stdout);
                   10115:     fclose (ficlog);
                   10116:     goto end;
                   10117:   }
1.126     brouard  10118:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10119:   delti=delti3[1][1];
                   10120:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   10121:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  10122: /* We could also provide initial parameters values giving by simple logistic regression 
                   10123:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   10124:       /* for(i=1;i<nlstate;i++){ */
                   10125:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10126:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10127:       /* } */
1.126     brouard  10128:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  10129:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   10130:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10131:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   10132:     fclose (ficparo);
                   10133:     fclose (ficlog);
                   10134:     goto end;
                   10135:     exit(0);
1.220     brouard  10136:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  10137:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  10138:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   10139:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10140:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10141:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10142:     hess=matrix(1,npar,1,npar);
1.220     brouard  10143:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  10144:     /* Read guessed parameters */
1.126     brouard  10145:     /* Reads comments: lines beginning with '#' */
                   10146:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10147:       ungetc(c,ficpar);
                   10148:       fgets(line, MAXLINE, ficpar);
                   10149:       numlinepar++;
1.141     brouard  10150:       fputs(line,stdout);
1.126     brouard  10151:       fputs(line,ficparo);
                   10152:       fputs(line,ficlog);
                   10153:     }
                   10154:     ungetc(c,ficpar);
                   10155:     
                   10156:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  10157:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  10158:     for(i=1; i <=nlstate; i++){
1.234     brouard  10159:       j=0;
1.126     brouard  10160:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  10161:        if(jj==i) continue;
                   10162:        j++;
                   10163:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10164:        if ((i1 != i) || (j1 != jj)){
                   10165:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  10166: It might be a problem of design; if ncovcol and the model are correct\n \
                   10167: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  10168:          exit(1);
                   10169:        }
                   10170:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10171:        if(mle==1)
                   10172:          printf("%1d%1d",i,jj);
                   10173:        fprintf(ficlog,"%1d%1d",i,jj);
                   10174:        for(k=1; k<=ncovmodel;k++){
                   10175:          fscanf(ficpar," %lf",&param[i][j][k]);
                   10176:          if(mle==1){
                   10177:            printf(" %lf",param[i][j][k]);
                   10178:            fprintf(ficlog," %lf",param[i][j][k]);
                   10179:          }
                   10180:          else
                   10181:            fprintf(ficlog," %lf",param[i][j][k]);
                   10182:          fprintf(ficparo," %lf",param[i][j][k]);
                   10183:        }
                   10184:        fscanf(ficpar,"\n");
                   10185:        numlinepar++;
                   10186:        if(mle==1)
                   10187:          printf("\n");
                   10188:        fprintf(ficlog,"\n");
                   10189:        fprintf(ficparo,"\n");
1.126     brouard  10190:       }
                   10191:     }  
                   10192:     fflush(ficlog);
1.234     brouard  10193:     
1.251     brouard  10194:     /* Reads parameters values */
1.126     brouard  10195:     p=param[1][1];
1.251     brouard  10196:     pstart=paramstart[1][1];
1.126     brouard  10197:     
                   10198:     /* Reads comments: lines beginning with '#' */
                   10199:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10200:       ungetc(c,ficpar);
                   10201:       fgets(line, MAXLINE, ficpar);
                   10202:       numlinepar++;
1.141     brouard  10203:       fputs(line,stdout);
1.126     brouard  10204:       fputs(line,ficparo);
                   10205:       fputs(line,ficlog);
                   10206:     }
                   10207:     ungetc(c,ficpar);
                   10208: 
                   10209:     for(i=1; i <=nlstate; i++){
                   10210:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  10211:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10212:        if ( (i1-i) * (j1-j) != 0){
                   10213:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   10214:          exit(1);
                   10215:        }
                   10216:        printf("%1d%1d",i,j);
                   10217:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10218:        fprintf(ficlog,"%1d%1d",i1,j1);
                   10219:        for(k=1; k<=ncovmodel;k++){
                   10220:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   10221:          printf(" %le",delti3[i][j][k]);
                   10222:          fprintf(ficparo," %le",delti3[i][j][k]);
                   10223:          fprintf(ficlog," %le",delti3[i][j][k]);
                   10224:        }
                   10225:        fscanf(ficpar,"\n");
                   10226:        numlinepar++;
                   10227:        printf("\n");
                   10228:        fprintf(ficparo,"\n");
                   10229:        fprintf(ficlog,"\n");
1.126     brouard  10230:       }
                   10231:     }
                   10232:     fflush(ficlog);
1.234     brouard  10233:     
1.145     brouard  10234:     /* Reads covariance matrix */
1.126     brouard  10235:     delti=delti3[1][1];
1.220     brouard  10236:                
                   10237:                
1.126     brouard  10238:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  10239:                
1.126     brouard  10240:     /* Reads comments: lines beginning with '#' */
                   10241:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10242:       ungetc(c,ficpar);
                   10243:       fgets(line, MAXLINE, ficpar);
                   10244:       numlinepar++;
1.141     brouard  10245:       fputs(line,stdout);
1.126     brouard  10246:       fputs(line,ficparo);
                   10247:       fputs(line,ficlog);
                   10248:     }
                   10249:     ungetc(c,ficpar);
1.220     brouard  10250:                
1.126     brouard  10251:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10252:     hess=matrix(1,npar,1,npar);
1.131     brouard  10253:     for(i=1; i <=npar; i++)
                   10254:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  10255:                
1.194     brouard  10256:     /* Scans npar lines */
1.126     brouard  10257:     for(i=1; i <=npar; i++){
1.226     brouard  10258:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  10259:       if(count != 3){
1.226     brouard  10260:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10261: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10262: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10263:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10264: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10265: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10266:        exit(1);
1.220     brouard  10267:       }else{
1.226     brouard  10268:        if(mle==1)
                   10269:          printf("%1d%1d%d",i1,j1,jk);
                   10270:       }
                   10271:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   10272:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  10273:       for(j=1; j <=i; j++){
1.226     brouard  10274:        fscanf(ficpar," %le",&matcov[i][j]);
                   10275:        if(mle==1){
                   10276:          printf(" %.5le",matcov[i][j]);
                   10277:        }
                   10278:        fprintf(ficlog," %.5le",matcov[i][j]);
                   10279:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  10280:       }
                   10281:       fscanf(ficpar,"\n");
                   10282:       numlinepar++;
                   10283:       if(mle==1)
1.220     brouard  10284:                                printf("\n");
1.126     brouard  10285:       fprintf(ficlog,"\n");
                   10286:       fprintf(ficparo,"\n");
                   10287:     }
1.194     brouard  10288:     /* End of read covariance matrix npar lines */
1.126     brouard  10289:     for(i=1; i <=npar; i++)
                   10290:       for(j=i+1;j<=npar;j++)
1.226     brouard  10291:        matcov[i][j]=matcov[j][i];
1.126     brouard  10292:     
                   10293:     if(mle==1)
                   10294:       printf("\n");
                   10295:     fprintf(ficlog,"\n");
                   10296:     
                   10297:     fflush(ficlog);
                   10298:     
                   10299:     /*-------- Rewriting parameter file ----------*/
                   10300:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   10301:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   10302:     strcat(rfileres,".");    /* */
                   10303:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10304:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  10305:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10306:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  10307:     }
                   10308:     fprintf(ficres,"#%s\n",version);
                   10309:   }    /* End of mle != -3 */
1.218     brouard  10310:   
1.186     brouard  10311:   /*  Main data
                   10312:    */
1.126     brouard  10313:   n= lastobs;
                   10314:   num=lvector(1,n);
                   10315:   moisnais=vector(1,n);
                   10316:   annais=vector(1,n);
                   10317:   moisdc=vector(1,n);
                   10318:   andc=vector(1,n);
1.220     brouard  10319:   weight=vector(1,n);
1.126     brouard  10320:   agedc=vector(1,n);
                   10321:   cod=ivector(1,n);
1.220     brouard  10322:   for(i=1;i<=n;i++){
1.234     brouard  10323:     num[i]=0;
                   10324:     moisnais[i]=0;
                   10325:     annais[i]=0;
                   10326:     moisdc[i]=0;
                   10327:     andc[i]=0;
                   10328:     agedc[i]=0;
                   10329:     cod[i]=0;
                   10330:     weight[i]=1.0; /* Equal weights, 1 by default */
                   10331:   }
1.126     brouard  10332:   mint=matrix(1,maxwav,1,n);
                   10333:   anint=matrix(1,maxwav,1,n);
1.131     brouard  10334:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  10335:   tab=ivector(1,NCOVMAX);
1.144     brouard  10336:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  10337:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  10338: 
1.136     brouard  10339:   /* Reads data from file datafile */
                   10340:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   10341:     goto end;
                   10342: 
                   10343:   /* Calculation of the number of parameters from char model */
1.234     brouard  10344:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  10345:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   10346:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   10347:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   10348:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  10349:   */
                   10350:   
                   10351:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   10352:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   10353:   TvarsD=ivector(1,NCOVMAX); /*  */
                   10354:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   10355:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  10356:   TvarF=ivector(1,NCOVMAX); /*  */
                   10357:   TvarFind=ivector(1,NCOVMAX); /*  */
                   10358:   TvarV=ivector(1,NCOVMAX); /*  */
                   10359:   TvarVind=ivector(1,NCOVMAX); /*  */
                   10360:   TvarA=ivector(1,NCOVMAX); /*  */
                   10361:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  10362:   TvarFD=ivector(1,NCOVMAX); /*  */
                   10363:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   10364:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   10365:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   10366:   TvarVD=ivector(1,NCOVMAX); /*  */
                   10367:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   10368:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   10369:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   10370: 
1.230     brouard  10371:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  10372:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  10373:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   10374:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   10375:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  10376:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   10377:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   10378:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   10379:   */
                   10380:   /* For model-covariate k tells which data-covariate to use but
                   10381:     because this model-covariate is a construction we invent a new column
                   10382:     ncovcol + k1
                   10383:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   10384:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  10385:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   10386:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  10387:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   10388:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  10389:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  10390:   */
1.145     brouard  10391:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   10392:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  10393:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   10394:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  10395:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  10396:                         4 covariates (3 plus signs)
                   10397:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   10398:                      */  
1.230     brouard  10399:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  10400:                                * individual dummy, fixed or varying:
                   10401:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   10402:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  10403:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   10404:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   10405:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   10406:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   10407:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  10408:                                * individual quantitative, fixed or varying:
                   10409:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   10410:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   10411:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  10412: /* Main decodemodel */
                   10413: 
1.187     brouard  10414: 
1.223     brouard  10415:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  10416:     goto end;
                   10417: 
1.137     brouard  10418:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   10419:     nbwarn++;
                   10420:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10421:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10422:   }
1.136     brouard  10423:     /*  if(mle==1){*/
1.137     brouard  10424:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   10425:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  10426:   }
                   10427: 
                   10428:     /*-calculation of age at interview from date of interview and age at death -*/
                   10429:   agev=matrix(1,maxwav,1,imx);
                   10430: 
                   10431:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   10432:     goto end;
                   10433: 
1.126     brouard  10434: 
1.136     brouard  10435:   agegomp=(int)agemin;
                   10436:   free_vector(moisnais,1,n);
                   10437:   free_vector(annais,1,n);
1.126     brouard  10438:   /* free_matrix(mint,1,maxwav,1,n);
                   10439:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  10440:   /* free_vector(moisdc,1,n); */
                   10441:   /* free_vector(andc,1,n); */
1.145     brouard  10442:   /* */
                   10443:   
1.126     brouard  10444:   wav=ivector(1,imx);
1.214     brouard  10445:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10446:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10447:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10448:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   10449:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   10450:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  10451:    
                   10452:   /* Concatenates waves */
1.214     brouard  10453:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   10454:      Death is a valid wave (if date is known).
                   10455:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   10456:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   10457:      and mw[mi+1][i]. dh depends on stepm.
                   10458:   */
                   10459: 
1.126     brouard  10460:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  10461:   /* Concatenates waves */
1.145     brouard  10462:  
1.215     brouard  10463:   free_vector(moisdc,1,n);
                   10464:   free_vector(andc,1,n);
                   10465: 
1.126     brouard  10466:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   10467:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   10468:   ncodemax[1]=1;
1.145     brouard  10469:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  10470:   cptcoveff=0;
1.220     brouard  10471:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   10472:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  10473:   }
                   10474:   
                   10475:   ncovcombmax=pow(2,cptcoveff);
                   10476:   invalidvarcomb=ivector(1, ncovcombmax); 
                   10477:   for(i=1;i<ncovcombmax;i++)
                   10478:     invalidvarcomb[i]=0;
                   10479:   
1.211     brouard  10480:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  10481:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  10482:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  10483:   
1.200     brouard  10484:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  10485:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  10486:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  10487:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   10488:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   10489:    * (currently 0 or 1) in the data.
                   10490:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   10491:    * corresponding modality (h,j).
                   10492:    */
                   10493: 
1.145     brouard  10494:   h=0;
                   10495:   /*if (cptcovn > 0) */
1.126     brouard  10496:   m=pow(2,cptcoveff);
                   10497:  
1.144     brouard  10498:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  10499:           * For k=4 covariates, h goes from 1 to m=2**k
                   10500:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   10501:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  10502:           *     h\k   1     2     3     4
1.143     brouard  10503:           *______________________________  
                   10504:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   10505:           *     2     2     1     1     1
                   10506:           *     3 i=2 1     2     1     1
                   10507:           *     4     2     2     1     1
                   10508:           *     5 i=3 1 i=2 1     2     1
                   10509:           *     6     2     1     2     1
                   10510:           *     7 i=4 1     2     2     1
                   10511:           *     8     2     2     2     1
1.197     brouard  10512:           *     9 i=5 1 i=3 1 i=2 1     2
                   10513:           *    10     2     1     1     2
                   10514:           *    11 i=6 1     2     1     2
                   10515:           *    12     2     2     1     2
                   10516:           *    13 i=7 1 i=4 1     2     2    
                   10517:           *    14     2     1     2     2
                   10518:           *    15 i=8 1     2     2     2
                   10519:           *    16     2     2     2     2
1.143     brouard  10520:           */
1.212     brouard  10521:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  10522:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   10523:      * and the value of each covariate?
                   10524:      * V1=1, V2=1, V3=2, V4=1 ?
                   10525:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   10526:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   10527:      * In order to get the real value in the data, we use nbcode
                   10528:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   10529:      * We are keeping this crazy system in order to be able (in the future?) 
                   10530:      * to have more than 2 values (0 or 1) for a covariate.
                   10531:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   10532:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   10533:      *              bbbbbbbb
                   10534:      *              76543210     
                   10535:      *   h-1        00000101 (6-1=5)
1.219     brouard  10536:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  10537:      *           &
                   10538:      *     1        00000001 (1)
1.219     brouard  10539:      *              00000000        = 1 & ((h-1) >> (k-1))
                   10540:      *          +1= 00000001 =1 
1.211     brouard  10541:      *
                   10542:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   10543:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   10544:      *    >>k'            11
                   10545:      *          &   00000001
                   10546:      *            = 00000001
                   10547:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   10548:      * Reverse h=6 and m=16?
                   10549:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   10550:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   10551:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   10552:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   10553:      * V3=decodtabm(14,3,2**4)=2
                   10554:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   10555:      *(h-1) >> (j-1)    0011 =13 >> 2
                   10556:      *          &1 000000001
                   10557:      *           = 000000001
                   10558:      *         +1= 000000010 =2
                   10559:      *                  2211
                   10560:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   10561:      *                  V3=2
1.220     brouard  10562:                 * codtabm and decodtabm are identical
1.211     brouard  10563:      */
                   10564: 
1.145     brouard  10565: 
                   10566:  free_ivector(Ndum,-1,NCOVMAX);
                   10567: 
                   10568: 
1.126     brouard  10569:     
1.186     brouard  10570:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  10571:   strcpy(optionfilegnuplot,optionfilefiname);
                   10572:   if(mle==-3)
1.201     brouard  10573:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  10574:   strcat(optionfilegnuplot,".gp");
                   10575: 
                   10576:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   10577:     printf("Problem with file %s",optionfilegnuplot);
                   10578:   }
                   10579:   else{
1.204     brouard  10580:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  10581:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  10582:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   10583:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  10584:   }
                   10585:   /*  fclose(ficgp);*/
1.186     brouard  10586: 
                   10587: 
                   10588:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  10589: 
                   10590:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   10591:   if(mle==-3)
1.201     brouard  10592:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  10593:   strcat(optionfilehtm,".htm");
                   10594:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  10595:     printf("Problem with %s \n",optionfilehtm);
                   10596:     exit(0);
1.126     brouard  10597:   }
                   10598: 
                   10599:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   10600:   strcat(optionfilehtmcov,"-cov.htm");
                   10601:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   10602:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   10603:   }
                   10604:   else{
                   10605:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   10606: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10607: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  10608:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   10609:   }
                   10610: 
1.213     brouard  10611:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  10612: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   10613: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  10614: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10615: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  10616: \n\
                   10617: <hr  size=\"2\" color=\"#EC5E5E\">\
                   10618:  <ul><li><h4>Parameter files</h4>\n\
                   10619:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   10620:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   10621:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   10622:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   10623:  - Date and time at start: %s</ul>\n",\
                   10624:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   10625:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   10626:          fileres,fileres,\
                   10627:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   10628:   fflush(fichtm);
                   10629: 
                   10630:   strcpy(pathr,path);
                   10631:   strcat(pathr,optionfilefiname);
1.184     brouard  10632: #ifdef WIN32
                   10633:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   10634: #else
1.126     brouard  10635:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  10636: #endif
                   10637:          
1.126     brouard  10638:   
1.220     brouard  10639:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   10640:                 and for any valid combination of covariates
1.126     brouard  10641:      and prints on file fileres'p'. */
1.251     brouard  10642:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  10643:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  10644: 
                   10645:   fprintf(fichtm,"\n");
                   10646:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   10647: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   10648: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   10649:          imx,agemin,agemax,jmin,jmax,jmean);
                   10650:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.220     brouard  10651:        oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10652:        newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10653:        savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10654:        oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  10655: 
1.126     brouard  10656:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   10657:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   10658:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   10659: 
                   10660:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  10661:   /* For mortality only */
1.126     brouard  10662:   if (mle==-3){
1.136     brouard  10663:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  10664:     for(i=1;i<=NDIM;i++)
                   10665:       for(j=1;j<=NDIM;j++)
                   10666:        ximort[i][j]=0.;
1.186     brouard  10667:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  10668:     cens=ivector(1,n);
                   10669:     ageexmed=vector(1,n);
                   10670:     agecens=vector(1,n);
                   10671:     dcwave=ivector(1,n);
1.223     brouard  10672:                
1.126     brouard  10673:     for (i=1; i<=imx; i++){
                   10674:       dcwave[i]=-1;
                   10675:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  10676:        if (s[m][i]>nlstate) {
                   10677:          dcwave[i]=m;
                   10678:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   10679:          break;
                   10680:        }
1.126     brouard  10681:     }
1.226     brouard  10682:     
1.126     brouard  10683:     for (i=1; i<=imx; i++) {
                   10684:       if (wav[i]>0){
1.226     brouard  10685:        ageexmed[i]=agev[mw[1][i]][i];
                   10686:        j=wav[i];
                   10687:        agecens[i]=1.; 
                   10688:        
                   10689:        if (ageexmed[i]> 1 && wav[i] > 0){
                   10690:          agecens[i]=agev[mw[j][i]][i];
                   10691:          cens[i]= 1;
                   10692:        }else if (ageexmed[i]< 1) 
                   10693:          cens[i]= -1;
                   10694:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   10695:          cens[i]=0 ;
1.126     brouard  10696:       }
                   10697:       else cens[i]=-1;
                   10698:     }
                   10699:     
                   10700:     for (i=1;i<=NDIM;i++) {
                   10701:       for (j=1;j<=NDIM;j++)
1.226     brouard  10702:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  10703:     }
                   10704:     
1.145     brouard  10705:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  10706:     /*printf("%lf %lf", p[1], p[2]);*/
                   10707:     
                   10708:     
1.136     brouard  10709: #ifdef GSL
                   10710:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  10711: #else
1.126     brouard  10712:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  10713: #endif
1.201     brouard  10714:     strcpy(filerespow,"POW-MORT_"); 
                   10715:     strcat(filerespow,fileresu);
1.126     brouard  10716:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   10717:       printf("Problem with resultfile: %s\n", filerespow);
                   10718:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   10719:     }
1.136     brouard  10720: #ifdef GSL
                   10721:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  10722: #else
1.126     brouard  10723:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  10724: #endif
1.126     brouard  10725:     /*  for (i=1;i<=nlstate;i++)
                   10726:        for(j=1;j<=nlstate+ndeath;j++)
                   10727:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   10728:     */
                   10729:     fprintf(ficrespow,"\n");
1.136     brouard  10730: #ifdef GSL
                   10731:     /* gsl starts here */ 
                   10732:     T = gsl_multimin_fminimizer_nmsimplex;
                   10733:     gsl_multimin_fminimizer *sfm = NULL;
                   10734:     gsl_vector *ss, *x;
                   10735:     gsl_multimin_function minex_func;
                   10736: 
                   10737:     /* Initial vertex size vector */
                   10738:     ss = gsl_vector_alloc (NDIM);
                   10739:     
                   10740:     if (ss == NULL){
                   10741:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   10742:     }
                   10743:     /* Set all step sizes to 1 */
                   10744:     gsl_vector_set_all (ss, 0.001);
                   10745: 
                   10746:     /* Starting point */
1.126     brouard  10747:     
1.136     brouard  10748:     x = gsl_vector_alloc (NDIM);
                   10749:     
                   10750:     if (x == NULL){
                   10751:       gsl_vector_free(ss);
                   10752:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   10753:     }
                   10754:   
                   10755:     /* Initialize method and iterate */
                   10756:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  10757:     /*     gsl_vector_set(x, 0, 0.0268); */
                   10758:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  10759:     gsl_vector_set(x, 0, p[1]);
                   10760:     gsl_vector_set(x, 1, p[2]);
                   10761: 
                   10762:     minex_func.f = &gompertz_f;
                   10763:     minex_func.n = NDIM;
                   10764:     minex_func.params = (void *)&p; /* ??? */
                   10765:     
                   10766:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   10767:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   10768:     
                   10769:     printf("Iterations beginning .....\n\n");
                   10770:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   10771: 
                   10772:     iteri=0;
                   10773:     while (rval == GSL_CONTINUE){
                   10774:       iteri++;
                   10775:       status = gsl_multimin_fminimizer_iterate(sfm);
                   10776:       
                   10777:       if (status) printf("error: %s\n", gsl_strerror (status));
                   10778:       fflush(0);
                   10779:       
                   10780:       if (status) 
                   10781:         break;
                   10782:       
                   10783:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   10784:       ssval = gsl_multimin_fminimizer_size (sfm);
                   10785:       
                   10786:       if (rval == GSL_SUCCESS)
                   10787:         printf ("converged to a local maximum at\n");
                   10788:       
                   10789:       printf("%5d ", iteri);
                   10790:       for (it = 0; it < NDIM; it++){
                   10791:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   10792:       }
                   10793:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   10794:     }
                   10795:     
                   10796:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   10797:     
                   10798:     gsl_vector_free(x); /* initial values */
                   10799:     gsl_vector_free(ss); /* inital step size */
                   10800:     for (it=0; it<NDIM; it++){
                   10801:       p[it+1]=gsl_vector_get(sfm->x,it);
                   10802:       fprintf(ficrespow," %.12lf", p[it]);
                   10803:     }
                   10804:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   10805: #endif
                   10806: #ifdef POWELL
                   10807:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   10808: #endif  
1.126     brouard  10809:     fclose(ficrespow);
                   10810:     
1.203     brouard  10811:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  10812: 
                   10813:     for(i=1; i <=NDIM; i++)
                   10814:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  10815:                                matcov[i][j]=matcov[j][i];
1.126     brouard  10816:     
                   10817:     printf("\nCovariance matrix\n ");
1.203     brouard  10818:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  10819:     for(i=1; i <=NDIM; i++) {
                   10820:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  10821:                                printf("%f ",matcov[i][j]);
                   10822:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  10823:       }
1.203     brouard  10824:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  10825:     }
                   10826:     
                   10827:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  10828:     for (i=1;i<=NDIM;i++) {
1.126     brouard  10829:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  10830:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   10831:     }
1.126     brouard  10832:     lsurv=vector(1,AGESUP);
                   10833:     lpop=vector(1,AGESUP);
                   10834:     tpop=vector(1,AGESUP);
                   10835:     lsurv[agegomp]=100000;
                   10836:     
                   10837:     for (k=agegomp;k<=AGESUP;k++) {
                   10838:       agemortsup=k;
                   10839:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   10840:     }
                   10841:     
                   10842:     for (k=agegomp;k<agemortsup;k++)
                   10843:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   10844:     
                   10845:     for (k=agegomp;k<agemortsup;k++){
                   10846:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   10847:       sumlpop=sumlpop+lpop[k];
                   10848:     }
                   10849:     
                   10850:     tpop[agegomp]=sumlpop;
                   10851:     for (k=agegomp;k<(agemortsup-3);k++){
                   10852:       /*  tpop[k+1]=2;*/
                   10853:       tpop[k+1]=tpop[k]-lpop[k];
                   10854:     }
                   10855:     
                   10856:     
                   10857:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   10858:     for (k=agegomp;k<(agemortsup-2);k++) 
                   10859:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   10860:     
                   10861:     
                   10862:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  10863:                ageminpar=50;
                   10864:                agemaxpar=100;
1.194     brouard  10865:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   10866:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10867: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10868: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   10869:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10870: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10871: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10872:     }else{
                   10873:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   10874:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  10875:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  10876:                }
1.201     brouard  10877:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  10878:                     stepm, weightopt,\
                   10879:                     model,imx,p,matcov,agemortsup);
                   10880:     
                   10881:     free_vector(lsurv,1,AGESUP);
                   10882:     free_vector(lpop,1,AGESUP);
                   10883:     free_vector(tpop,1,AGESUP);
1.220     brouard  10884:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  10885:     free_ivector(cens,1,n);
                   10886:     free_vector(agecens,1,n);
                   10887:     free_ivector(dcwave,1,n);
1.220     brouard  10888: #ifdef GSL
1.136     brouard  10889: #endif
1.186     brouard  10890:   } /* Endof if mle==-3 mortality only */
1.205     brouard  10891:   /* Standard  */
                   10892:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   10893:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10894:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  10895:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  10896:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10897:     for (k=1; k<=npar;k++)
                   10898:       printf(" %d %8.5f",k,p[k]);
                   10899:     printf("\n");
1.205     brouard  10900:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   10901:       /* mlikeli uses func not funcone */
1.247     brouard  10902:       /* for(i=1;i<nlstate;i++){ */
                   10903:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10904:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10905:       /* } */
1.205     brouard  10906:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   10907:     }
                   10908:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   10909:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10910:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   10911:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10912:     }
                   10913:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  10914:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10915:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10916:     for (k=1; k<=npar;k++)
                   10917:       printf(" %d %8.5f",k,p[k]);
                   10918:     printf("\n");
                   10919:     
                   10920:     /*--------- results files --------------*/
1.224     brouard  10921:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  10922:     
                   10923:     
                   10924:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10925:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10926:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10927:     for(i=1,jk=1; i <=nlstate; i++){
                   10928:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  10929:        if (k != i) {
                   10930:          printf("%d%d ",i,k);
                   10931:          fprintf(ficlog,"%d%d ",i,k);
                   10932:          fprintf(ficres,"%1d%1d ",i,k);
                   10933:          for(j=1; j <=ncovmodel; j++){
                   10934:            printf("%12.7f ",p[jk]);
                   10935:            fprintf(ficlog,"%12.7f ",p[jk]);
                   10936:            fprintf(ficres,"%12.7f ",p[jk]);
                   10937:            jk++; 
                   10938:          }
                   10939:          printf("\n");
                   10940:          fprintf(ficlog,"\n");
                   10941:          fprintf(ficres,"\n");
                   10942:        }
1.126     brouard  10943:       }
                   10944:     }
1.203     brouard  10945:     if(mle != 0){
                   10946:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  10947:       ftolhess=ftol; /* Usually correct */
1.203     brouard  10948:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   10949:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10950:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10951:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  10952:        for(k=1; k <=(nlstate+ndeath); k++){
                   10953:          if (k != i) {
                   10954:            printf("%d%d ",i,k);
                   10955:            fprintf(ficlog,"%d%d ",i,k);
                   10956:            for(j=1; j <=ncovmodel; j++){
                   10957:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10958:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10959:              jk++; 
                   10960:            }
                   10961:            printf("\n");
                   10962:            fprintf(ficlog,"\n");
                   10963:          }
                   10964:        }
1.193     brouard  10965:       }
1.203     brouard  10966:     } /* end of hesscov and Wald tests */
1.225     brouard  10967:     
1.203     brouard  10968:     /*  */
1.126     brouard  10969:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   10970:     printf("# Scales (for hessian or gradient estimation)\n");
                   10971:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   10972:     for(i=1,jk=1; i <=nlstate; i++){
                   10973:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  10974:        if (j!=i) {
                   10975:          fprintf(ficres,"%1d%1d",i,j);
                   10976:          printf("%1d%1d",i,j);
                   10977:          fprintf(ficlog,"%1d%1d",i,j);
                   10978:          for(k=1; k<=ncovmodel;k++){
                   10979:            printf(" %.5e",delti[jk]);
                   10980:            fprintf(ficlog," %.5e",delti[jk]);
                   10981:            fprintf(ficres," %.5e",delti[jk]);
                   10982:            jk++;
                   10983:          }
                   10984:          printf("\n");
                   10985:          fprintf(ficlog,"\n");
                   10986:          fprintf(ficres,"\n");
                   10987:        }
1.126     brouard  10988:       }
                   10989:     }
                   10990:     
                   10991:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  10992:     if(mle >= 1) /* To big for the screen */
1.126     brouard  10993:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   10994:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   10995:     /* # 121 Var(a12)\n\ */
                   10996:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   10997:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   10998:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   10999:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   11000:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   11001:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   11002:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   11003:     
                   11004:     
                   11005:     /* Just to have a covariance matrix which will be more understandable
                   11006:        even is we still don't want to manage dictionary of variables
                   11007:     */
                   11008:     for(itimes=1;itimes<=2;itimes++){
                   11009:       jj=0;
                   11010:       for(i=1; i <=nlstate; i++){
1.225     brouard  11011:        for(j=1; j <=nlstate+ndeath; j++){
                   11012:          if(j==i) continue;
                   11013:          for(k=1; k<=ncovmodel;k++){
                   11014:            jj++;
                   11015:            ca[0]= k+'a'-1;ca[1]='\0';
                   11016:            if(itimes==1){
                   11017:              if(mle>=1)
                   11018:                printf("#%1d%1d%d",i,j,k);
                   11019:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   11020:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   11021:            }else{
                   11022:              if(mle>=1)
                   11023:                printf("%1d%1d%d",i,j,k);
                   11024:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   11025:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   11026:            }
                   11027:            ll=0;
                   11028:            for(li=1;li <=nlstate; li++){
                   11029:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   11030:                if(lj==li) continue;
                   11031:                for(lk=1;lk<=ncovmodel;lk++){
                   11032:                  ll++;
                   11033:                  if(ll<=jj){
                   11034:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   11035:                    if(ll<jj){
                   11036:                      if(itimes==1){
                   11037:                        if(mle>=1)
                   11038:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11039:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11040:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11041:                      }else{
                   11042:                        if(mle>=1)
                   11043:                          printf(" %.5e",matcov[jj][ll]); 
                   11044:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   11045:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   11046:                      }
                   11047:                    }else{
                   11048:                      if(itimes==1){
                   11049:                        if(mle>=1)
                   11050:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   11051:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   11052:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   11053:                      }else{
                   11054:                        if(mle>=1)
                   11055:                          printf(" %.7e",matcov[jj][ll]); 
                   11056:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   11057:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   11058:                      }
                   11059:                    }
                   11060:                  }
                   11061:                } /* end lk */
                   11062:              } /* end lj */
                   11063:            } /* end li */
                   11064:            if(mle>=1)
                   11065:              printf("\n");
                   11066:            fprintf(ficlog,"\n");
                   11067:            fprintf(ficres,"\n");
                   11068:            numlinepar++;
                   11069:          } /* end k*/
                   11070:        } /*end j */
1.126     brouard  11071:       } /* end i */
                   11072:     } /* end itimes */
                   11073:     
                   11074:     fflush(ficlog);
                   11075:     fflush(ficres);
1.225     brouard  11076:     while(fgets(line, MAXLINE, ficpar)) {
                   11077:       /* If line starts with a # it is a comment */
                   11078:       if (line[0] == '#') {
                   11079:        numlinepar++;
                   11080:        fputs(line,stdout);
                   11081:        fputs(line,ficparo);
                   11082:        fputs(line,ficlog);
                   11083:        continue;
                   11084:       }else
                   11085:        break;
                   11086:     }
                   11087:     
1.209     brouard  11088:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11089:     /*   ungetc(c,ficpar); */
                   11090:     /*   fgets(line, MAXLINE, ficpar); */
                   11091:     /*   fputs(line,stdout); */
                   11092:     /*   fputs(line,ficparo); */
                   11093:     /* } */
                   11094:     /* ungetc(c,ficpar); */
1.126     brouard  11095:     
                   11096:     estepm=0;
1.209     brouard  11097:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  11098:       
                   11099:       if (num_filled != 6) {
                   11100:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11101:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11102:        goto end;
                   11103:       }
                   11104:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   11105:     }
                   11106:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   11107:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   11108:     
1.209     brouard  11109:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  11110:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   11111:     if (fage <= 2) {
                   11112:       bage = ageminpar;
                   11113:       fage = agemaxpar;
                   11114:     }
                   11115:     
                   11116:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  11117:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   11118:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  11119:                
1.186     brouard  11120:     /* Other stuffs, more or less useful */    
1.254     brouard  11121:     while(fgets(line, MAXLINE, ficpar)) {
                   11122:       /* If line starts with a # it is a comment */
                   11123:       if (line[0] == '#') {
                   11124:        numlinepar++;
                   11125:        fputs(line,stdout);
                   11126:        fputs(line,ficparo);
                   11127:        fputs(line,ficlog);
                   11128:        continue;
                   11129:       }else
                   11130:        break;
                   11131:     }
                   11132: 
                   11133:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   11134:       
                   11135:       if (num_filled != 7) {
                   11136:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11137:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11138:        goto end;
                   11139:       }
                   11140:     /* fscanf(ficpar,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav); */
                   11141:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11142:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11143:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11144:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11145:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  11146:     }
1.254     brouard  11147: 
                   11148:     while(fgets(line, MAXLINE, ficpar)) {
                   11149:       /* If line starts with a # it is a comment */
                   11150:       if (line[0] == '#') {
                   11151:        numlinepar++;
                   11152:        fputs(line,stdout);
                   11153:        fputs(line,ficparo);
                   11154:        fputs(line,ficlog);
                   11155:        continue;
                   11156:       }else
                   11157:        break;
1.126     brouard  11158:     }
                   11159:     
                   11160:     
                   11161:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   11162:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   11163:     
1.254     brouard  11164:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   11165:       if (num_filled != 1) {
                   11166:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11167:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11168:        goto end;
                   11169:       }
                   11170:       printf("pop_based=%d\n",popbased);
                   11171:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   11172:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   11173:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   11174:     }
                   11175:      
                   11176:     while(fgets(line, MAXLINE, ficpar)) {
                   11177:       /* If line starts with a # it is a comment */
                   11178:       if (line[0] == '#') {
                   11179:        numlinepar++;
                   11180:        fputs(line,stdout);
                   11181:        fputs(line,ficparo);
                   11182:        fputs(line,ficlog);
                   11183:        continue;
                   11184:       }else
                   11185:        break;
1.126     brouard  11186:     }
1.254     brouard  11187:    /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11188:    /*    ungetc(c,ficpar); */
                   11189:    /*    fgets(line, MAXLINE, ficpar); */
                   11190:    /*    fputs(line,stdout); */
                   11191:    /*    fputs(line,ficres); */
                   11192:    /*    fputs(line,ficparo); */
                   11193:    /*  } */
                   11194:    /*  ungetc(c,ficpar); */
                   11195:     
                   11196:     /* fscanf(ficpar,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj); */
                   11197:     if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   11198:       if (num_filled != 8) {
                   11199:        printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11200:        fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11201:        goto end;
                   11202:       }
                   11203:      fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11204:      printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11205:      fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11206:      fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
1.126     brouard  11207:     /* day and month of proj2 are not used but only year anproj2.*/
1.217     brouard  11208:     }
1.254     brouard  11209:      while(fgets(line, MAXLINE, ficpar)) {
                   11210:       /* If line starts with a # it is a comment */
                   11211:       if (line[0] == '#') {
                   11212:        numlinepar++;
                   11213:        fputs(line,stdout);
                   11214:        fputs(line,ficparo);
                   11215:        fputs(line,ficlog);
                   11216:        continue;
                   11217:       }else
                   11218:        break;
                   11219:     }
                   11220:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11221:     /*   ungetc(c,ficpar); */
                   11222:     /*   fgets(line, MAXLINE, ficpar); */
                   11223:     /*   fputs(line,stdout); */
                   11224:     /*   fputs(line,ficparo); */
                   11225:     /*   fputs(line,ficres); */
                   11226:     /* } */
                   11227:     /* ungetc(c,ficpar); */
1.217     brouard  11228:     
                   11229:     fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);
1.254     brouard  11230:     if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   11231:       if (num_filled != 8) {
                   11232:        printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 finloal-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11233:        fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 finloal-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11234:        goto end;
                   11235:       }
                   11236:       printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11237:       fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11238:       fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11239:       fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
1.217     brouard  11240:     /* day and month of proj2 are not used but only year anproj2.*/
1.254     brouard  11241:     }
1.230     brouard  11242:     /* Results */
1.235     brouard  11243:     nresult=0;
1.230     brouard  11244:     while(fgets(line, MAXLINE, ficpar)) {
                   11245:       /* If line starts with a # it is a comment */
                   11246:       if (line[0] == '#') {
                   11247:        numlinepar++;
                   11248:        fputs(line,stdout);
                   11249:        fputs(line,ficparo);
                   11250:        fputs(line,ficlog);
1.238     brouard  11251:        fputs(line,ficres);
1.230     brouard  11252:        continue;
                   11253:       }else
                   11254:        break;
                   11255:     }
1.240     brouard  11256:     if (!feof(ficpar))
1.230     brouard  11257:     while((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
1.240     brouard  11258:       if (num_filled == 0){
1.230     brouard  11259:        resultline[0]='\0';
1.253     brouard  11260:        printf("Warning %d: no result line should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
1.240     brouard  11261:       break;
                   11262:       } else if (num_filled != 1){
1.253     brouard  11263:        printf("ERROR %d: result line should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
1.230     brouard  11264:       }
1.235     brouard  11265:       nresult++; /* Sum of resultlines */
                   11266:       printf("Result %d: result=%s\n",nresult, resultline);
                   11267:       if(nresult > MAXRESULTLINES){
                   11268:        printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11269:        fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11270:        goto end;
                   11271:       }
                   11272:       decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
1.238     brouard  11273:       fprintf(ficparo,"result: %s\n",resultline);
                   11274:       fprintf(ficres,"result: %s\n",resultline);
                   11275:       fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  11276:       while(fgets(line, MAXLINE, ficpar)) {
                   11277:        /* If line starts with a # it is a comment */
                   11278:        if (line[0] == '#') {
                   11279:          numlinepar++;
                   11280:          fputs(line,stdout);
                   11281:          fputs(line,ficparo);
1.238     brouard  11282:          fputs(line,ficres);
1.230     brouard  11283:          fputs(line,ficlog);
                   11284:          continue;
                   11285:        }else
                   11286:          break;
                   11287:       }
                   11288:       if (feof(ficpar))
                   11289:        break;
                   11290:       else{ /* Processess output results for this combination of covariate values */
                   11291:       }                                   
1.240     brouard  11292:     } /* end while */
1.230     brouard  11293: 
                   11294: 
1.126     brouard  11295:     
1.230     brouard  11296:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  11297:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  11298:     
                   11299:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  11300:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  11301:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11302: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11303: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  11304:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11305: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11306: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11307:     }else{
1.218     brouard  11308:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p);
1.220     brouard  11309:     }
                   11310:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.225     brouard  11311:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,prevfcast,backcast, estepm, \
                   11312:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  11313:                
1.225     brouard  11314:     /*------------ free_vector  -------------*/
                   11315:     /*  chdir(path); */
1.220     brouard  11316:                
1.215     brouard  11317:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   11318:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   11319:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   11320:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  11321:     free_lvector(num,1,n);
                   11322:     free_vector(agedc,1,n);
                   11323:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   11324:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   11325:     fclose(ficparo);
                   11326:     fclose(ficres);
1.220     brouard  11327:                
                   11328:                
1.186     brouard  11329:     /* Other results (useful)*/
1.220     brouard  11330:                
                   11331:                
1.126     brouard  11332:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  11333:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   11334:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  11335:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  11336:     fclose(ficrespl);
                   11337: 
                   11338:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  11339:     /*#include "hpijx.h"*/
                   11340:     hPijx(p, bage, fage);
1.145     brouard  11341:     fclose(ficrespij);
1.227     brouard  11342:     
1.220     brouard  11343:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  11344:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  11345:     k=1;
1.126     brouard  11346:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  11347:     
1.219     brouard  11348:     /* Prevalence for each covariates in probs[age][status][cov] */
1.218     brouard  11349:     probs= ma3x(1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.126     brouard  11350:     for(i=1;i<=AGESUP;i++)
1.219     brouard  11351:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  11352:        for(k=1;k<=ncovcombmax;k++)
                   11353:          probs[i][j][k]=0.;
1.219     brouard  11354:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
                   11355:     if (mobilav!=0 ||mobilavproj !=0 ) {
                   11356:       mobaverages= ma3x(1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.227     brouard  11357:       for(i=1;i<=AGESUP;i++)
                   11358:        for(j=1;j<=nlstate;j++)
                   11359:          for(k=1;k<=ncovcombmax;k++)
                   11360:            mobaverages[i][j][k]=0.;
1.219     brouard  11361:       mobaverage=mobaverages;
                   11362:       if (mobilav!=0) {
1.235     brouard  11363:        printf("Movingaveraging observed prevalence\n");
1.227     brouard  11364:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   11365:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   11366:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   11367:        }
1.219     brouard  11368:       }
                   11369:       /* /\* Prevalence for each covariates in probs[age][status][cov] *\/ */
                   11370:       /* prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   11371:       else if (mobilavproj !=0) {
1.235     brouard  11372:        printf("Movingaveraging projected observed prevalence\n");
1.227     brouard  11373:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   11374:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11375:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11376:        }
1.219     brouard  11377:       }
                   11378:     }/* end if moving average */
1.227     brouard  11379:     
1.126     brouard  11380:     /*---------- Forecasting ------------------*/
                   11381:     /*if((stepm == 1) && (strcmp(model,".")==0)){*/
                   11382:     if(prevfcast==1){
                   11383:       /*    if(stepm ==1){*/
1.225     brouard  11384:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  11385:     }
1.217     brouard  11386:     if(backcast==1){
1.219     brouard  11387:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11388:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11389:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   11390: 
                   11391:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   11392: 
                   11393:       bprlim=matrix(1,nlstate,1,nlstate);
                   11394:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   11395:       fclose(ficresplb);
                   11396: 
1.222     brouard  11397:       hBijx(p, bage, fage, mobaverage);
                   11398:       fclose(ficrespijb);
1.219     brouard  11399:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11400: 
                   11401:       /* prevbackforecast(fileresu, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, mobilavproj,
1.225     brouard  11402:         bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
1.219     brouard  11403:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11404:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11405:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11406:     }
1.217     brouard  11407:     
1.186     brouard  11408:  
                   11409:     /* ------ Other prevalence ratios------------ */
1.126     brouard  11410: 
1.215     brouard  11411:     free_ivector(wav,1,imx);
                   11412:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   11413:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   11414:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  11415:                
                   11416:                
1.127     brouard  11417:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  11418:                
1.201     brouard  11419:     strcpy(filerese,"E_");
                   11420:     strcat(filerese,fileresu);
1.126     brouard  11421:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   11422:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11423:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11424:     }
1.208     brouard  11425:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   11426:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  11427: 
                   11428:     pstamp(ficreseij);
1.219     brouard  11429:                
1.235     brouard  11430:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11431:     if (cptcovn < 1){i1=1;}
                   11432:     
                   11433:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11434:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11435:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11436:        continue;
1.219     brouard  11437:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  11438:       printf("\n#****** ");
1.225     brouard  11439:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11440:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11441:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11442:       }
                   11443:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11444:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11445:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  11446:       }
                   11447:       fprintf(ficreseij,"******\n");
1.235     brouard  11448:       printf("******\n");
1.219     brouard  11449:       
                   11450:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11451:       oldm=oldms;savm=savms;
1.235     brouard  11452:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  11453:       
1.219     brouard  11454:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  11455:     }
                   11456:     fclose(ficreseij);
1.208     brouard  11457:     printf("done evsij\n");fflush(stdout);
                   11458:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.218     brouard  11459:                
1.227     brouard  11460:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  11461:                
                   11462:                
1.201     brouard  11463:     strcpy(filerest,"T_");
                   11464:     strcat(filerest,fileresu);
1.127     brouard  11465:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   11466:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   11467:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   11468:     }
1.208     brouard  11469:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   11470:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.218     brouard  11471:                
1.126     brouard  11472: 
1.201     brouard  11473:     strcpy(fileresstde,"STDE_");
                   11474:     strcat(fileresstde,fileresu);
1.126     brouard  11475:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  11476:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   11477:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  11478:     }
1.227     brouard  11479:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   11480:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  11481: 
1.201     brouard  11482:     strcpy(filerescve,"CVE_");
                   11483:     strcat(filerescve,fileresu);
1.126     brouard  11484:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  11485:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   11486:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  11487:     }
1.227     brouard  11488:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   11489:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  11490: 
1.201     brouard  11491:     strcpy(fileresv,"V_");
                   11492:     strcat(fileresv,fileresu);
1.126     brouard  11493:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   11494:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11495:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11496:     }
1.227     brouard  11497:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   11498:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  11499: 
1.145     brouard  11500:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11501:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   11502:           
1.235     brouard  11503:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11504:     if (cptcovn < 1){i1=1;}
                   11505:     
                   11506:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11507:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11508:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11509:        continue;
1.242     brouard  11510:       printf("\n#****** Result for:");
                   11511:       fprintf(ficrest,"\n#****** Result for:");
                   11512:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  11513:       for(j=1;j<=cptcoveff;j++){ 
                   11514:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11515:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11516:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11517:       }
1.235     brouard  11518:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11519:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11520:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11521:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11522:       }        
1.208     brouard  11523:       fprintf(ficrest,"******\n");
1.227     brouard  11524:       fprintf(ficlog,"******\n");
                   11525:       printf("******\n");
1.208     brouard  11526:       
                   11527:       fprintf(ficresstdeij,"\n#****** ");
                   11528:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  11529:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11530:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11531:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  11532:       }
1.235     brouard  11533:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11534:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11535:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11536:       }        
1.208     brouard  11537:       fprintf(ficresstdeij,"******\n");
                   11538:       fprintf(ficrescveij,"******\n");
                   11539:       
                   11540:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  11541:       /* pstamp(ficresvij); */
1.225     brouard  11542:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  11543:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11544:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11545:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11546:       }        
1.208     brouard  11547:       fprintf(ficresvij,"******\n");
                   11548:       
                   11549:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11550:       oldm=oldms;savm=savms;
1.235     brouard  11551:       printf(" cvevsij ");
                   11552:       fprintf(ficlog, " cvevsij ");
                   11553:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  11554:       printf(" end cvevsij \n ");
                   11555:       fprintf(ficlog, " end cvevsij \n ");
                   11556:       
                   11557:       /*
                   11558:        */
                   11559:       /* goto endfree; */
                   11560:       
                   11561:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11562:       pstamp(ficrest);
                   11563:       
                   11564:       
                   11565:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  11566:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   11567:        cptcod= 0; /* To be deleted */
                   11568:        printf("varevsij vpopbased=%d \n",vpopbased);
                   11569:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  11570:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  11571:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   11572:        if(vpopbased==1)
                   11573:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   11574:        else
                   11575:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   11576:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   11577:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   11578:        fprintf(ficrest,"\n");
                   11579:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   11580:        epj=vector(1,nlstate+1);
                   11581:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   11582:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   11583:        for(age=bage; age <=fage ;age++){
1.235     brouard  11584:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  11585:          if (vpopbased==1) {
                   11586:            if(mobilav ==0){
                   11587:              for(i=1; i<=nlstate;i++)
                   11588:                prlim[i][i]=probs[(int)age][i][k];
                   11589:            }else{ /* mobilav */ 
                   11590:              for(i=1; i<=nlstate;i++)
                   11591:                prlim[i][i]=mobaverage[(int)age][i][k];
                   11592:            }
                   11593:          }
1.219     brouard  11594:          
1.227     brouard  11595:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   11596:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   11597:          /* printf(" age %4.0f ",age); */
                   11598:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   11599:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   11600:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   11601:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   11602:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   11603:            }
                   11604:            epj[nlstate+1] +=epj[j];
                   11605:          }
                   11606:          /* printf(" age %4.0f \n",age); */
1.219     brouard  11607:          
1.227     brouard  11608:          for(i=1, vepp=0.;i <=nlstate;i++)
                   11609:            for(j=1;j <=nlstate;j++)
                   11610:              vepp += vareij[i][j][(int)age];
                   11611:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   11612:          for(j=1;j <=nlstate;j++){
                   11613:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   11614:          }
                   11615:          fprintf(ficrest,"\n");
                   11616:        }
1.208     brouard  11617:       } /* End vpopbased */
                   11618:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11619:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11620:       free_vector(epj,1,nlstate+1);
1.235     brouard  11621:       printf("done selection\n");fflush(stdout);
                   11622:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  11623:       
1.145     brouard  11624:       /*}*/
1.235     brouard  11625:     } /* End k selection */
1.227     brouard  11626: 
                   11627:     printf("done State-specific expectancies\n");fflush(stdout);
                   11628:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   11629: 
1.126     brouard  11630:     /*------- Variance of period (stable) prevalence------*/   
1.227     brouard  11631:     
1.201     brouard  11632:     strcpy(fileresvpl,"VPL_");
                   11633:     strcat(fileresvpl,fileresu);
1.126     brouard  11634:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   11635:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   11636:       exit(0);
                   11637:     }
1.208     brouard  11638:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   11639:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.227     brouard  11640:     
1.145     brouard  11641:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11642:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
1.227     brouard  11643:     
1.235     brouard  11644:     i1=pow(2,cptcoveff);
                   11645:     if (cptcovn < 1){i1=1;}
                   11646: 
                   11647:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11648:     for(k=1; k<=i1;k++){
1.253     brouard  11649:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11650:        continue;
1.227     brouard  11651:       fprintf(ficresvpl,"\n#****** ");
                   11652:       printf("\n#****** ");
                   11653:       fprintf(ficlog,"\n#****** ");
                   11654:       for(j=1;j<=cptcoveff;j++) {
                   11655:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11656:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11657:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11658:       }
1.235     brouard  11659:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11660:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11661:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11662:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11663:       }        
1.227     brouard  11664:       fprintf(ficresvpl,"******\n");
                   11665:       printf("******\n");
                   11666:       fprintf(ficlog,"******\n");
                   11667:       
                   11668:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   11669:       oldm=oldms;savm=savms;
1.235     brouard  11670:       varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, strstart, nres);
1.227     brouard  11671:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
1.145     brouard  11672:       /*}*/
1.126     brouard  11673:     }
1.227     brouard  11674:     
1.126     brouard  11675:     fclose(ficresvpl);
1.208     brouard  11676:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   11677:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
1.227     brouard  11678:     
                   11679:     free_vector(weight,1,n);
                   11680:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   11681:     free_imatrix(s,1,maxwav+1,1,n);
                   11682:     free_matrix(anint,1,maxwav,1,n); 
                   11683:     free_matrix(mint,1,maxwav,1,n);
                   11684:     free_ivector(cod,1,n);
                   11685:     free_ivector(tab,1,NCOVMAX);
                   11686:     fclose(ficresstdeij);
                   11687:     fclose(ficrescveij);
                   11688:     fclose(ficresvij);
                   11689:     fclose(ficrest);
                   11690:     fclose(ficpar);
                   11691:     
                   11692:     
1.126     brouard  11693:     /*---------- End : free ----------------*/
1.219     brouard  11694:     if (mobilav!=0 ||mobilavproj !=0)
                   11695:       free_ma3x(mobaverages,1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
1.218     brouard  11696:     free_ma3x(probs,1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  11697:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11698:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  11699:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  11700:   /* endfree:*/
                   11701:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11702:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11703:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11704:   free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
1.233     brouard  11705:   free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
1.227     brouard  11706:   free_matrix(coqvar,1,maxwav,1,n);
                   11707:   free_matrix(covar,0,NCOVMAX,1,n);
                   11708:   free_matrix(matcov,1,npar,1,npar);
                   11709:   free_matrix(hess,1,npar,1,npar);
                   11710:   /*free_vector(delti,1,npar);*/
                   11711:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11712:   free_matrix(agev,1,maxwav,1,imx);
                   11713:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   11714:   
                   11715:   free_ivector(ncodemax,1,NCOVMAX);
                   11716:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   11717:   free_ivector(Dummy,-1,NCOVMAX);
                   11718:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  11719:   free_ivector(DummyV,1,NCOVMAX);
                   11720:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  11721:   free_ivector(Typevar,-1,NCOVMAX);
                   11722:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  11723:   free_ivector(TvarsQ,1,NCOVMAX);
                   11724:   free_ivector(TvarsQind,1,NCOVMAX);
                   11725:   free_ivector(TvarsD,1,NCOVMAX);
                   11726:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  11727:   free_ivector(TvarFD,1,NCOVMAX);
                   11728:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  11729:   free_ivector(TvarF,1,NCOVMAX);
                   11730:   free_ivector(TvarFind,1,NCOVMAX);
                   11731:   free_ivector(TvarV,1,NCOVMAX);
                   11732:   free_ivector(TvarVind,1,NCOVMAX);
                   11733:   free_ivector(TvarA,1,NCOVMAX);
                   11734:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  11735:   free_ivector(TvarFQ,1,NCOVMAX);
                   11736:   free_ivector(TvarFQind,1,NCOVMAX);
                   11737:   free_ivector(TvarVD,1,NCOVMAX);
                   11738:   free_ivector(TvarVDind,1,NCOVMAX);
                   11739:   free_ivector(TvarVQ,1,NCOVMAX);
                   11740:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  11741:   free_ivector(Tvarsel,1,NCOVMAX);
                   11742:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  11743:   free_ivector(Tposprod,1,NCOVMAX);
                   11744:   free_ivector(Tprod,1,NCOVMAX);
                   11745:   free_ivector(Tvaraff,1,NCOVMAX);
                   11746:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   11747:   free_ivector(Tage,1,NCOVMAX);
                   11748:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  11749:   free_ivector(TmodelInvind,1,NCOVMAX);
                   11750:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  11751:   
                   11752:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   11753:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  11754:   fflush(fichtm);
                   11755:   fflush(ficgp);
                   11756:   
1.227     brouard  11757:   
1.126     brouard  11758:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  11759:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   11760:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  11761:   }else{
                   11762:     printf("End of Imach\n");
                   11763:     fprintf(ficlog,"End of Imach\n");
                   11764:   }
                   11765:   printf("See log file on %s\n",filelog);
                   11766:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  11767:   /*(void) gettimeofday(&end_time,&tzp);*/
                   11768:   rend_time = time(NULL);  
                   11769:   end_time = *localtime(&rend_time);
                   11770:   /* tml = *localtime(&end_time.tm_sec); */
                   11771:   strcpy(strtend,asctime(&end_time));
1.126     brouard  11772:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   11773:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  11774:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  11775:   
1.157     brouard  11776:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   11777:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   11778:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  11779:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   11780: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   11781:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11782:   fclose(fichtm);
                   11783:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11784:   fclose(fichtmcov);
                   11785:   fclose(ficgp);
                   11786:   fclose(ficlog);
                   11787:   /*------ End -----------*/
1.227     brouard  11788:   
                   11789:   
                   11790:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  11791: #ifdef WIN32
1.227     brouard  11792:   if (_chdir(pathcd) != 0)
                   11793:     printf("Can't move to directory %s!\n",path);
                   11794:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  11795: #else
1.227     brouard  11796:     if(chdir(pathcd) != 0)
                   11797:       printf("Can't move to directory %s!\n", path);
                   11798:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  11799: #endif 
1.126     brouard  11800:     printf("Current directory %s!\n",pathcd);
                   11801:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   11802:   sprintf(plotcmd,"gnuplot");
1.157     brouard  11803: #ifdef _WIN32
1.126     brouard  11804:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   11805: #endif
                   11806:   if(!stat(plotcmd,&info)){
1.158     brouard  11807:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11808:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  11809:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  11810:     }else
                   11811:       strcpy(pplotcmd,plotcmd);
1.157     brouard  11812: #ifdef __unix
1.126     brouard  11813:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   11814:     if(!stat(plotcmd,&info)){
1.158     brouard  11815:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11816:     }else
                   11817:       strcpy(pplotcmd,plotcmd);
                   11818: #endif
                   11819:   }else
                   11820:     strcpy(pplotcmd,plotcmd);
                   11821:   
                   11822:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  11823:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  11824:   
1.126     brouard  11825:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  11826:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  11827:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  11828:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  11829:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  11830:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  11831:   }
1.158     brouard  11832:   printf(" Successful, please wait...");
1.126     brouard  11833:   while (z[0] != 'q') {
                   11834:     /* chdir(path); */
1.154     brouard  11835:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  11836:     scanf("%s",z);
                   11837: /*     if (z[0] == 'c') system("./imach"); */
                   11838:     if (z[0] == 'e') {
1.158     brouard  11839: #ifdef __APPLE__
1.152     brouard  11840:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  11841: #elif __linux
                   11842:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  11843: #else
1.152     brouard  11844:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  11845: #endif
                   11846:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   11847:       system(pplotcmd);
1.126     brouard  11848:     }
                   11849:     else if (z[0] == 'g') system(plotcmd);
                   11850:     else if (z[0] == 'q') exit(0);
                   11851:   }
1.227     brouard  11852: end:
1.126     brouard  11853:   while (z[0] != 'q') {
1.195     brouard  11854:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  11855:     scanf("%s",z);
                   11856:   }
                   11857: }

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