Annotation of imach/src/imach.c, revision 1.256

1.256   ! brouard     1: /* $Id: imach.c,v 1.255 2017/03/08 16:02:28 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.256   ! brouard     4:   Revision 1.255  2017/03/08 16:02:28  brouard
        !             5:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
        !             6: 
1.255     brouard     7:   Revision 1.254  2017/03/08 07:13:00  brouard
                      8:   Summary: Fixing data parameter line
                      9: 
1.254     brouard    10:   Revision 1.253  2016/12/15 11:59:41  brouard
                     11:   Summary: 0.99 in progress
                     12: 
1.253     brouard    13:   Revision 1.252  2016/09/15 21:15:37  brouard
                     14:   *** empty log message ***
                     15: 
1.252     brouard    16:   Revision 1.251  2016/09/15 15:01:13  brouard
                     17:   Summary: not working
                     18: 
1.251     brouard    19:   Revision 1.250  2016/09/08 16:07:27  brouard
                     20:   Summary: continue
                     21: 
1.250     brouard    22:   Revision 1.249  2016/09/07 17:14:18  brouard
                     23:   Summary: Starting values from frequencies
                     24: 
1.249     brouard    25:   Revision 1.248  2016/09/07 14:10:18  brouard
                     26:   *** empty log message ***
                     27: 
1.248     brouard    28:   Revision 1.247  2016/09/02 11:11:21  brouard
                     29:   *** empty log message ***
                     30: 
1.247     brouard    31:   Revision 1.246  2016/09/02 08:49:22  brouard
                     32:   *** empty log message ***
                     33: 
1.246     brouard    34:   Revision 1.245  2016/09/02 07:25:01  brouard
                     35:   *** empty log message ***
                     36: 
1.245     brouard    37:   Revision 1.244  2016/09/02 07:17:34  brouard
                     38:   *** empty log message ***
                     39: 
1.244     brouard    40:   Revision 1.243  2016/09/02 06:45:35  brouard
                     41:   *** empty log message ***
                     42: 
1.243     brouard    43:   Revision 1.242  2016/08/30 15:01:20  brouard
                     44:   Summary: Fixing a lots
                     45: 
1.242     brouard    46:   Revision 1.241  2016/08/29 17:17:25  brouard
                     47:   Summary: gnuplot problem in Back projection to fix
                     48: 
1.241     brouard    49:   Revision 1.240  2016/08/29 07:53:18  brouard
                     50:   Summary: Better
                     51: 
1.240     brouard    52:   Revision 1.239  2016/08/26 15:51:03  brouard
                     53:   Summary: Improvement in Powell output in order to copy and paste
                     54: 
                     55:   Author:
                     56: 
1.239     brouard    57:   Revision 1.238  2016/08/26 14:23:35  brouard
                     58:   Summary: Starting tests of 0.99
                     59: 
1.238     brouard    60:   Revision 1.237  2016/08/26 09:20:19  brouard
                     61:   Summary: to valgrind
                     62: 
1.237     brouard    63:   Revision 1.236  2016/08/25 10:50:18  brouard
                     64:   *** empty log message ***
                     65: 
1.236     brouard    66:   Revision 1.235  2016/08/25 06:59:23  brouard
                     67:   *** empty log message ***
                     68: 
1.235     brouard    69:   Revision 1.234  2016/08/23 16:51:20  brouard
                     70:   *** empty log message ***
                     71: 
1.234     brouard    72:   Revision 1.233  2016/08/23 07:40:50  brouard
                     73:   Summary: not working
                     74: 
1.233     brouard    75:   Revision 1.232  2016/08/22 14:20:21  brouard
                     76:   Summary: not working
                     77: 
1.232     brouard    78:   Revision 1.231  2016/08/22 07:17:15  brouard
                     79:   Summary: not working
                     80: 
1.231     brouard    81:   Revision 1.230  2016/08/22 06:55:53  brouard
                     82:   Summary: Not working
                     83: 
1.230     brouard    84:   Revision 1.229  2016/07/23 09:45:53  brouard
                     85:   Summary: Completing for func too
                     86: 
1.229     brouard    87:   Revision 1.228  2016/07/22 17:45:30  brouard
                     88:   Summary: Fixing some arrays, still debugging
                     89: 
1.227     brouard    90:   Revision 1.226  2016/07/12 18:42:34  brouard
                     91:   Summary: temp
                     92: 
1.226     brouard    93:   Revision 1.225  2016/07/12 08:40:03  brouard
                     94:   Summary: saving but not running
                     95: 
1.225     brouard    96:   Revision 1.224  2016/07/01 13:16:01  brouard
                     97:   Summary: Fixes
                     98: 
1.224     brouard    99:   Revision 1.223  2016/02/19 09:23:35  brouard
                    100:   Summary: temporary
                    101: 
1.223     brouard   102:   Revision 1.222  2016/02/17 08:14:50  brouard
                    103:   Summary: Probably last 0.98 stable version 0.98r6
                    104: 
1.222     brouard   105:   Revision 1.221  2016/02/15 23:35:36  brouard
                    106:   Summary: minor bug
                    107: 
1.220     brouard   108:   Revision 1.219  2016/02/15 00:48:12  brouard
                    109:   *** empty log message ***
                    110: 
1.219     brouard   111:   Revision 1.218  2016/02/12 11:29:23  brouard
                    112:   Summary: 0.99 Back projections
                    113: 
1.218     brouard   114:   Revision 1.217  2015/12/23 17:18:31  brouard
                    115:   Summary: Experimental backcast
                    116: 
1.217     brouard   117:   Revision 1.216  2015/12/18 17:32:11  brouard
                    118:   Summary: 0.98r4 Warning and status=-2
                    119: 
                    120:   Version 0.98r4 is now:
                    121:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    122:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    123:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    124: 
1.216     brouard   125:   Revision 1.215  2015/12/16 08:52:24  brouard
                    126:   Summary: 0.98r4 working
                    127: 
1.215     brouard   128:   Revision 1.214  2015/12/16 06:57:54  brouard
                    129:   Summary: temporary not working
                    130: 
1.214     brouard   131:   Revision 1.213  2015/12/11 18:22:17  brouard
                    132:   Summary: 0.98r4
                    133: 
1.213     brouard   134:   Revision 1.212  2015/11/21 12:47:24  brouard
                    135:   Summary: minor typo
                    136: 
1.212     brouard   137:   Revision 1.211  2015/11/21 12:41:11  brouard
                    138:   Summary: 0.98r3 with some graph of projected cross-sectional
                    139: 
                    140:   Author: Nicolas Brouard
                    141: 
1.211     brouard   142:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   143:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   144:   Summary: Adding ftolpl parameter
                    145:   Author: N Brouard
                    146: 
                    147:   We had difficulties to get smoothed confidence intervals. It was due
                    148:   to the period prevalence which wasn't computed accurately. The inner
                    149:   parameter ftolpl is now an outer parameter of the .imach parameter
                    150:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    151:   computation are long.
                    152: 
1.209     brouard   153:   Revision 1.208  2015/11/17 14:31:57  brouard
                    154:   Summary: temporary
                    155: 
1.208     brouard   156:   Revision 1.207  2015/10/27 17:36:57  brouard
                    157:   *** empty log message ***
                    158: 
1.207     brouard   159:   Revision 1.206  2015/10/24 07:14:11  brouard
                    160:   *** empty log message ***
                    161: 
1.206     brouard   162:   Revision 1.205  2015/10/23 15:50:53  brouard
                    163:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    164: 
1.205     brouard   165:   Revision 1.204  2015/10/01 16:20:26  brouard
                    166:   Summary: Some new graphs of contribution to likelihood
                    167: 
1.204     brouard   168:   Revision 1.203  2015/09/30 17:45:14  brouard
                    169:   Summary: looking at better estimation of the hessian
                    170: 
                    171:   Also a better criteria for convergence to the period prevalence And
                    172:   therefore adding the number of years needed to converge. (The
                    173:   prevalence in any alive state shold sum to one
                    174: 
1.203     brouard   175:   Revision 1.202  2015/09/22 19:45:16  brouard
                    176:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    177: 
1.202     brouard   178:   Revision 1.201  2015/09/15 17:34:58  brouard
                    179:   Summary: 0.98r0
                    180: 
                    181:   - Some new graphs like suvival functions
                    182:   - Some bugs fixed like model=1+age+V2.
                    183: 
1.201     brouard   184:   Revision 1.200  2015/09/09 16:53:55  brouard
                    185:   Summary: Big bug thanks to Flavia
                    186: 
                    187:   Even model=1+age+V2. did not work anymore
                    188: 
1.200     brouard   189:   Revision 1.199  2015/09/07 14:09:23  brouard
                    190:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    191: 
1.199     brouard   192:   Revision 1.198  2015/09/03 07:14:39  brouard
                    193:   Summary: 0.98q5 Flavia
                    194: 
1.198     brouard   195:   Revision 1.197  2015/09/01 18:24:39  brouard
                    196:   *** empty log message ***
                    197: 
1.197     brouard   198:   Revision 1.196  2015/08/18 23:17:52  brouard
                    199:   Summary: 0.98q5
                    200: 
1.196     brouard   201:   Revision 1.195  2015/08/18 16:28:39  brouard
                    202:   Summary: Adding a hack for testing purpose
                    203: 
                    204:   After reading the title, ftol and model lines, if the comment line has
                    205:   a q, starting with #q, the answer at the end of the run is quit. It
                    206:   permits to run test files in batch with ctest. The former workaround was
                    207:   $ echo q | imach foo.imach
                    208: 
1.195     brouard   209:   Revision 1.194  2015/08/18 13:32:00  brouard
                    210:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    211: 
1.194     brouard   212:   Revision 1.193  2015/08/04 07:17:42  brouard
                    213:   Summary: 0.98q4
                    214: 
1.193     brouard   215:   Revision 1.192  2015/07/16 16:49:02  brouard
                    216:   Summary: Fixing some outputs
                    217: 
1.192     brouard   218:   Revision 1.191  2015/07/14 10:00:33  brouard
                    219:   Summary: Some fixes
                    220: 
1.191     brouard   221:   Revision 1.190  2015/05/05 08:51:13  brouard
                    222:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    223: 
                    224:   Fix 1+age+.
                    225: 
1.190     brouard   226:   Revision 1.189  2015/04/30 14:45:16  brouard
                    227:   Summary: 0.98q2
                    228: 
1.189     brouard   229:   Revision 1.188  2015/04/30 08:27:53  brouard
                    230:   *** empty log message ***
                    231: 
1.188     brouard   232:   Revision 1.187  2015/04/29 09:11:15  brouard
                    233:   *** empty log message ***
                    234: 
1.187     brouard   235:   Revision 1.186  2015/04/23 12:01:52  brouard
                    236:   Summary: V1*age is working now, version 0.98q1
                    237: 
                    238:   Some codes had been disabled in order to simplify and Vn*age was
                    239:   working in the optimization phase, ie, giving correct MLE parameters,
                    240:   but, as usual, outputs were not correct and program core dumped.
                    241: 
1.186     brouard   242:   Revision 1.185  2015/03/11 13:26:42  brouard
                    243:   Summary: Inclusion of compile and links command line for Intel Compiler
                    244: 
1.185     brouard   245:   Revision 1.184  2015/03/11 11:52:39  brouard
                    246:   Summary: Back from Windows 8. Intel Compiler
                    247: 
1.184     brouard   248:   Revision 1.183  2015/03/10 20:34:32  brouard
                    249:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    250: 
                    251:   We use directest instead of original Powell test; probably no
                    252:   incidence on the results, but better justifications;
                    253:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    254:   wrong results.
                    255: 
1.183     brouard   256:   Revision 1.182  2015/02/12 08:19:57  brouard
                    257:   Summary: Trying to keep directest which seems simpler and more general
                    258:   Author: Nicolas Brouard
                    259: 
1.182     brouard   260:   Revision 1.181  2015/02/11 23:22:24  brouard
                    261:   Summary: Comments on Powell added
                    262: 
                    263:   Author:
                    264: 
1.181     brouard   265:   Revision 1.180  2015/02/11 17:33:45  brouard
                    266:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    267: 
1.180     brouard   268:   Revision 1.179  2015/01/04 09:57:06  brouard
                    269:   Summary: back to OS/X
                    270: 
1.179     brouard   271:   Revision 1.178  2015/01/04 09:35:48  brouard
                    272:   *** empty log message ***
                    273: 
1.178     brouard   274:   Revision 1.177  2015/01/03 18:40:56  brouard
                    275:   Summary: Still testing ilc32 on OSX
                    276: 
1.177     brouard   277:   Revision 1.176  2015/01/03 16:45:04  brouard
                    278:   *** empty log message ***
                    279: 
1.176     brouard   280:   Revision 1.175  2015/01/03 16:33:42  brouard
                    281:   *** empty log message ***
                    282: 
1.175     brouard   283:   Revision 1.174  2015/01/03 16:15:49  brouard
                    284:   Summary: Still in cross-compilation
                    285: 
1.174     brouard   286:   Revision 1.173  2015/01/03 12:06:26  brouard
                    287:   Summary: trying to detect cross-compilation
                    288: 
1.173     brouard   289:   Revision 1.172  2014/12/27 12:07:47  brouard
                    290:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    291: 
1.172     brouard   292:   Revision 1.171  2014/12/23 13:26:59  brouard
                    293:   Summary: Back from Visual C
                    294: 
                    295:   Still problem with utsname.h on Windows
                    296: 
1.171     brouard   297:   Revision 1.170  2014/12/23 11:17:12  brouard
                    298:   Summary: Cleaning some \%% back to %%
                    299: 
                    300:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    301: 
1.170     brouard   302:   Revision 1.169  2014/12/22 23:08:31  brouard
                    303:   Summary: 0.98p
                    304: 
                    305:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    306: 
1.169     brouard   307:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   308:   Summary: update
1.169     brouard   309: 
1.168     brouard   310:   Revision 1.167  2014/12/22 13:50:56  brouard
                    311:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    312: 
                    313:   Testing on Linux 64
                    314: 
1.167     brouard   315:   Revision 1.166  2014/12/22 11:40:47  brouard
                    316:   *** empty log message ***
                    317: 
1.166     brouard   318:   Revision 1.165  2014/12/16 11:20:36  brouard
                    319:   Summary: After compiling on Visual C
                    320: 
                    321:   * imach.c (Module): Merging 1.61 to 1.162
                    322: 
1.165     brouard   323:   Revision 1.164  2014/12/16 10:52:11  brouard
                    324:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    325: 
                    326:   * imach.c (Module): Merging 1.61 to 1.162
                    327: 
1.164     brouard   328:   Revision 1.163  2014/12/16 10:30:11  brouard
                    329:   * imach.c (Module): Merging 1.61 to 1.162
                    330: 
1.163     brouard   331:   Revision 1.162  2014/09/25 11:43:39  brouard
                    332:   Summary: temporary backup 0.99!
                    333: 
1.162     brouard   334:   Revision 1.1  2014/09/16 11:06:58  brouard
                    335:   Summary: With some code (wrong) for nlopt
                    336: 
                    337:   Author:
                    338: 
                    339:   Revision 1.161  2014/09/15 20:41:41  brouard
                    340:   Summary: Problem with macro SQR on Intel compiler
                    341: 
1.161     brouard   342:   Revision 1.160  2014/09/02 09:24:05  brouard
                    343:   *** empty log message ***
                    344: 
1.160     brouard   345:   Revision 1.159  2014/09/01 10:34:10  brouard
                    346:   Summary: WIN32
                    347:   Author: Brouard
                    348: 
1.159     brouard   349:   Revision 1.158  2014/08/27 17:11:51  brouard
                    350:   *** empty log message ***
                    351: 
1.158     brouard   352:   Revision 1.157  2014/08/27 16:26:55  brouard
                    353:   Summary: Preparing windows Visual studio version
                    354:   Author: Brouard
                    355: 
                    356:   In order to compile on Visual studio, time.h is now correct and time_t
                    357:   and tm struct should be used. difftime should be used but sometimes I
                    358:   just make the differences in raw time format (time(&now).
                    359:   Trying to suppress #ifdef LINUX
                    360:   Add xdg-open for __linux in order to open default browser.
                    361: 
1.157     brouard   362:   Revision 1.156  2014/08/25 20:10:10  brouard
                    363:   *** empty log message ***
                    364: 
1.156     brouard   365:   Revision 1.155  2014/08/25 18:32:34  brouard
                    366:   Summary: New compile, minor changes
                    367:   Author: Brouard
                    368: 
1.155     brouard   369:   Revision 1.154  2014/06/20 17:32:08  brouard
                    370:   Summary: Outputs now all graphs of convergence to period prevalence
                    371: 
1.154     brouard   372:   Revision 1.153  2014/06/20 16:45:46  brouard
                    373:   Summary: If 3 live state, convergence to period prevalence on same graph
                    374:   Author: Brouard
                    375: 
1.153     brouard   376:   Revision 1.152  2014/06/18 17:54:09  brouard
                    377:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    378: 
1.152     brouard   379:   Revision 1.151  2014/06/18 16:43:30  brouard
                    380:   *** empty log message ***
                    381: 
1.151     brouard   382:   Revision 1.150  2014/06/18 16:42:35  brouard
                    383:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    384:   Author: brouard
                    385: 
1.150     brouard   386:   Revision 1.149  2014/06/18 15:51:14  brouard
                    387:   Summary: Some fixes in parameter files errors
                    388:   Author: Nicolas Brouard
                    389: 
1.149     brouard   390:   Revision 1.148  2014/06/17 17:38:48  brouard
                    391:   Summary: Nothing new
                    392:   Author: Brouard
                    393: 
                    394:   Just a new packaging for OS/X version 0.98nS
                    395: 
1.148     brouard   396:   Revision 1.147  2014/06/16 10:33:11  brouard
                    397:   *** empty log message ***
                    398: 
1.147     brouard   399:   Revision 1.146  2014/06/16 10:20:28  brouard
                    400:   Summary: Merge
                    401:   Author: Brouard
                    402: 
                    403:   Merge, before building revised version.
                    404: 
1.146     brouard   405:   Revision 1.145  2014/06/10 21:23:15  brouard
                    406:   Summary: Debugging with valgrind
                    407:   Author: Nicolas Brouard
                    408: 
                    409:   Lot of changes in order to output the results with some covariates
                    410:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    411:   improve the code.
                    412:   No more memory valgrind error but a lot has to be done in order to
                    413:   continue the work of splitting the code into subroutines.
                    414:   Also, decodemodel has been improved. Tricode is still not
                    415:   optimal. nbcode should be improved. Documentation has been added in
                    416:   the source code.
                    417: 
1.144     brouard   418:   Revision 1.143  2014/01/26 09:45:38  brouard
                    419:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    420: 
                    421:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    422:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    423: 
1.143     brouard   424:   Revision 1.142  2014/01/26 03:57:36  brouard
                    425:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    426: 
                    427:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    428: 
1.142     brouard   429:   Revision 1.141  2014/01/26 02:42:01  brouard
                    430:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    431: 
1.141     brouard   432:   Revision 1.140  2011/09/02 10:37:54  brouard
                    433:   Summary: times.h is ok with mingw32 now.
                    434: 
1.140     brouard   435:   Revision 1.139  2010/06/14 07:50:17  brouard
                    436:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    437:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    438: 
1.139     brouard   439:   Revision 1.138  2010/04/30 18:19:40  brouard
                    440:   *** empty log message ***
                    441: 
1.138     brouard   442:   Revision 1.137  2010/04/29 18:11:38  brouard
                    443:   (Module): Checking covariates for more complex models
                    444:   than V1+V2. A lot of change to be done. Unstable.
                    445: 
1.137     brouard   446:   Revision 1.136  2010/04/26 20:30:53  brouard
                    447:   (Module): merging some libgsl code. Fixing computation
                    448:   of likelione (using inter/intrapolation if mle = 0) in order to
                    449:   get same likelihood as if mle=1.
                    450:   Some cleaning of code and comments added.
                    451: 
1.136     brouard   452:   Revision 1.135  2009/10/29 15:33:14  brouard
                    453:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    454: 
1.135     brouard   455:   Revision 1.134  2009/10/29 13:18:53  brouard
                    456:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    457: 
1.134     brouard   458:   Revision 1.133  2009/07/06 10:21:25  brouard
                    459:   just nforces
                    460: 
1.133     brouard   461:   Revision 1.132  2009/07/06 08:22:05  brouard
                    462:   Many tings
                    463: 
1.132     brouard   464:   Revision 1.131  2009/06/20 16:22:47  brouard
                    465:   Some dimensions resccaled
                    466: 
1.131     brouard   467:   Revision 1.130  2009/05/26 06:44:34  brouard
                    468:   (Module): Max Covariate is now set to 20 instead of 8. A
                    469:   lot of cleaning with variables initialized to 0. Trying to make
                    470:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    471: 
1.130     brouard   472:   Revision 1.129  2007/08/31 13:49:27  lievre
                    473:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    474: 
1.129     lievre    475:   Revision 1.128  2006/06/30 13:02:05  brouard
                    476:   (Module): Clarifications on computing e.j
                    477: 
1.128     brouard   478:   Revision 1.127  2006/04/28 18:11:50  brouard
                    479:   (Module): Yes the sum of survivors was wrong since
                    480:   imach-114 because nhstepm was no more computed in the age
                    481:   loop. Now we define nhstepma in the age loop.
                    482:   (Module): In order to speed up (in case of numerous covariates) we
                    483:   compute health expectancies (without variances) in a first step
                    484:   and then all the health expectancies with variances or standard
                    485:   deviation (needs data from the Hessian matrices) which slows the
                    486:   computation.
                    487:   In the future we should be able to stop the program is only health
                    488:   expectancies and graph are needed without standard deviations.
                    489: 
1.127     brouard   490:   Revision 1.126  2006/04/28 17:23:28  brouard
                    491:   (Module): Yes the sum of survivors was wrong since
                    492:   imach-114 because nhstepm was no more computed in the age
                    493:   loop. Now we define nhstepma in the age loop.
                    494:   Version 0.98h
                    495: 
1.126     brouard   496:   Revision 1.125  2006/04/04 15:20:31  lievre
                    497:   Errors in calculation of health expectancies. Age was not initialized.
                    498:   Forecasting file added.
                    499: 
                    500:   Revision 1.124  2006/03/22 17:13:53  lievre
                    501:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    502:   The log-likelihood is printed in the log file
                    503: 
                    504:   Revision 1.123  2006/03/20 10:52:43  brouard
                    505:   * imach.c (Module): <title> changed, corresponds to .htm file
                    506:   name. <head> headers where missing.
                    507: 
                    508:   * imach.c (Module): Weights can have a decimal point as for
                    509:   English (a comma might work with a correct LC_NUMERIC environment,
                    510:   otherwise the weight is truncated).
                    511:   Modification of warning when the covariates values are not 0 or
                    512:   1.
                    513:   Version 0.98g
                    514: 
                    515:   Revision 1.122  2006/03/20 09:45:41  brouard
                    516:   (Module): Weights can have a decimal point as for
                    517:   English (a comma might work with a correct LC_NUMERIC environment,
                    518:   otherwise the weight is truncated).
                    519:   Modification of warning when the covariates values are not 0 or
                    520:   1.
                    521:   Version 0.98g
                    522: 
                    523:   Revision 1.121  2006/03/16 17:45:01  lievre
                    524:   * imach.c (Module): Comments concerning covariates added
                    525: 
                    526:   * imach.c (Module): refinements in the computation of lli if
                    527:   status=-2 in order to have more reliable computation if stepm is
                    528:   not 1 month. Version 0.98f
                    529: 
                    530:   Revision 1.120  2006/03/16 15:10:38  lievre
                    531:   (Module): refinements in the computation of lli if
                    532:   status=-2 in order to have more reliable computation if stepm is
                    533:   not 1 month. Version 0.98f
                    534: 
                    535:   Revision 1.119  2006/03/15 17:42:26  brouard
                    536:   (Module): Bug if status = -2, the loglikelihood was
                    537:   computed as likelihood omitting the logarithm. Version O.98e
                    538: 
                    539:   Revision 1.118  2006/03/14 18:20:07  brouard
                    540:   (Module): varevsij Comments added explaining the second
                    541:   table of variances if popbased=1 .
                    542:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    543:   (Module): Function pstamp added
                    544:   (Module): Version 0.98d
                    545: 
                    546:   Revision 1.117  2006/03/14 17:16:22  brouard
                    547:   (Module): varevsij Comments added explaining the second
                    548:   table of variances if popbased=1 .
                    549:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    550:   (Module): Function pstamp added
                    551:   (Module): Version 0.98d
                    552: 
                    553:   Revision 1.116  2006/03/06 10:29:27  brouard
                    554:   (Module): Variance-covariance wrong links and
                    555:   varian-covariance of ej. is needed (Saito).
                    556: 
                    557:   Revision 1.115  2006/02/27 12:17:45  brouard
                    558:   (Module): One freematrix added in mlikeli! 0.98c
                    559: 
                    560:   Revision 1.114  2006/02/26 12:57:58  brouard
                    561:   (Module): Some improvements in processing parameter
                    562:   filename with strsep.
                    563: 
                    564:   Revision 1.113  2006/02/24 14:20:24  brouard
                    565:   (Module): Memory leaks checks with valgrind and:
                    566:   datafile was not closed, some imatrix were not freed and on matrix
                    567:   allocation too.
                    568: 
                    569:   Revision 1.112  2006/01/30 09:55:26  brouard
                    570:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    571: 
                    572:   Revision 1.111  2006/01/25 20:38:18  brouard
                    573:   (Module): Lots of cleaning and bugs added (Gompertz)
                    574:   (Module): Comments can be added in data file. Missing date values
                    575:   can be a simple dot '.'.
                    576: 
                    577:   Revision 1.110  2006/01/25 00:51:50  brouard
                    578:   (Module): Lots of cleaning and bugs added (Gompertz)
                    579: 
                    580:   Revision 1.109  2006/01/24 19:37:15  brouard
                    581:   (Module): Comments (lines starting with a #) are allowed in data.
                    582: 
                    583:   Revision 1.108  2006/01/19 18:05:42  lievre
                    584:   Gnuplot problem appeared...
                    585:   To be fixed
                    586: 
                    587:   Revision 1.107  2006/01/19 16:20:37  brouard
                    588:   Test existence of gnuplot in imach path
                    589: 
                    590:   Revision 1.106  2006/01/19 13:24:36  brouard
                    591:   Some cleaning and links added in html output
                    592: 
                    593:   Revision 1.105  2006/01/05 20:23:19  lievre
                    594:   *** empty log message ***
                    595: 
                    596:   Revision 1.104  2005/09/30 16:11:43  lievre
                    597:   (Module): sump fixed, loop imx fixed, and simplifications.
                    598:   (Module): If the status is missing at the last wave but we know
                    599:   that the person is alive, then we can code his/her status as -2
                    600:   (instead of missing=-1 in earlier versions) and his/her
                    601:   contributions to the likelihood is 1 - Prob of dying from last
                    602:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    603:   the healthy state at last known wave). Version is 0.98
                    604: 
                    605:   Revision 1.103  2005/09/30 15:54:49  lievre
                    606:   (Module): sump fixed, loop imx fixed, and simplifications.
                    607: 
                    608:   Revision 1.102  2004/09/15 17:31:30  brouard
                    609:   Add the possibility to read data file including tab characters.
                    610: 
                    611:   Revision 1.101  2004/09/15 10:38:38  brouard
                    612:   Fix on curr_time
                    613: 
                    614:   Revision 1.100  2004/07/12 18:29:06  brouard
                    615:   Add version for Mac OS X. Just define UNIX in Makefile
                    616: 
                    617:   Revision 1.99  2004/06/05 08:57:40  brouard
                    618:   *** empty log message ***
                    619: 
                    620:   Revision 1.98  2004/05/16 15:05:56  brouard
                    621:   New version 0.97 . First attempt to estimate force of mortality
                    622:   directly from the data i.e. without the need of knowing the health
                    623:   state at each age, but using a Gompertz model: log u =a + b*age .
                    624:   This is the basic analysis of mortality and should be done before any
                    625:   other analysis, in order to test if the mortality estimated from the
                    626:   cross-longitudinal survey is different from the mortality estimated
                    627:   from other sources like vital statistic data.
                    628: 
                    629:   The same imach parameter file can be used but the option for mle should be -3.
                    630: 
1.133     brouard   631:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   632:   former routines in order to include the new code within the former code.
                    633: 
                    634:   The output is very simple: only an estimate of the intercept and of
                    635:   the slope with 95% confident intervals.
                    636: 
                    637:   Current limitations:
                    638:   A) Even if you enter covariates, i.e. with the
                    639:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    640:   B) There is no computation of Life Expectancy nor Life Table.
                    641: 
                    642:   Revision 1.97  2004/02/20 13:25:42  lievre
                    643:   Version 0.96d. Population forecasting command line is (temporarily)
                    644:   suppressed.
                    645: 
                    646:   Revision 1.96  2003/07/15 15:38:55  brouard
                    647:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    648:   rewritten within the same printf. Workaround: many printfs.
                    649: 
                    650:   Revision 1.95  2003/07/08 07:54:34  brouard
                    651:   * imach.c (Repository):
                    652:   (Repository): Using imachwizard code to output a more meaningful covariance
                    653:   matrix (cov(a12,c31) instead of numbers.
                    654: 
                    655:   Revision 1.94  2003/06/27 13:00:02  brouard
                    656:   Just cleaning
                    657: 
                    658:   Revision 1.93  2003/06/25 16:33:55  brouard
                    659:   (Module): On windows (cygwin) function asctime_r doesn't
                    660:   exist so I changed back to asctime which exists.
                    661:   (Module): Version 0.96b
                    662: 
                    663:   Revision 1.92  2003/06/25 16:30:45  brouard
                    664:   (Module): On windows (cygwin) function asctime_r doesn't
                    665:   exist so I changed back to asctime which exists.
                    666: 
                    667:   Revision 1.91  2003/06/25 15:30:29  brouard
                    668:   * imach.c (Repository): Duplicated warning errors corrected.
                    669:   (Repository): Elapsed time after each iteration is now output. It
                    670:   helps to forecast when convergence will be reached. Elapsed time
                    671:   is stamped in powell.  We created a new html file for the graphs
                    672:   concerning matrix of covariance. It has extension -cov.htm.
                    673: 
                    674:   Revision 1.90  2003/06/24 12:34:15  brouard
                    675:   (Module): Some bugs corrected for windows. Also, when
                    676:   mle=-1 a template is output in file "or"mypar.txt with the design
                    677:   of the covariance matrix to be input.
                    678: 
                    679:   Revision 1.89  2003/06/24 12:30:52  brouard
                    680:   (Module): Some bugs corrected for windows. Also, when
                    681:   mle=-1 a template is output in file "or"mypar.txt with the design
                    682:   of the covariance matrix to be input.
                    683: 
                    684:   Revision 1.88  2003/06/23 17:54:56  brouard
                    685:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    686: 
                    687:   Revision 1.87  2003/06/18 12:26:01  brouard
                    688:   Version 0.96
                    689: 
                    690:   Revision 1.86  2003/06/17 20:04:08  brouard
                    691:   (Module): Change position of html and gnuplot routines and added
                    692:   routine fileappend.
                    693: 
                    694:   Revision 1.85  2003/06/17 13:12:43  brouard
                    695:   * imach.c (Repository): Check when date of death was earlier that
                    696:   current date of interview. It may happen when the death was just
                    697:   prior to the death. In this case, dh was negative and likelihood
                    698:   was wrong (infinity). We still send an "Error" but patch by
                    699:   assuming that the date of death was just one stepm after the
                    700:   interview.
                    701:   (Repository): Because some people have very long ID (first column)
                    702:   we changed int to long in num[] and we added a new lvector for
                    703:   memory allocation. But we also truncated to 8 characters (left
                    704:   truncation)
                    705:   (Repository): No more line truncation errors.
                    706: 
                    707:   Revision 1.84  2003/06/13 21:44:43  brouard
                    708:   * imach.c (Repository): Replace "freqsummary" at a correct
                    709:   place. It differs from routine "prevalence" which may be called
                    710:   many times. Probs is memory consuming and must be used with
                    711:   parcimony.
                    712:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    713: 
                    714:   Revision 1.83  2003/06/10 13:39:11  lievre
                    715:   *** empty log message ***
                    716: 
                    717:   Revision 1.82  2003/06/05 15:57:20  brouard
                    718:   Add log in  imach.c and  fullversion number is now printed.
                    719: 
                    720: */
                    721: /*
                    722:    Interpolated Markov Chain
                    723: 
                    724:   Short summary of the programme:
                    725:   
1.227     brouard   726:   This program computes Healthy Life Expectancies or State-specific
                    727:   (if states aren't health statuses) Expectancies from
                    728:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    729: 
                    730:   -1- a first survey ("cross") where individuals from different ages
                    731:   are interviewed on their health status or degree of disability (in
                    732:   the case of a health survey which is our main interest)
                    733: 
                    734:   -2- at least a second wave of interviews ("longitudinal") which
                    735:   measure each change (if any) in individual health status.  Health
                    736:   expectancies are computed from the time spent in each health state
                    737:   according to a model. More health states you consider, more time is
                    738:   necessary to reach the Maximum Likelihood of the parameters involved
                    739:   in the model.  The simplest model is the multinomial logistic model
                    740:   where pij is the probability to be observed in state j at the second
                    741:   wave conditional to be observed in state i at the first
                    742:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    743:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    744:   have a more complex model than "constant and age", you should modify
                    745:   the program where the markup *Covariates have to be included here
                    746:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   747:   convergence.
                    748: 
                    749:   The advantage of this computer programme, compared to a simple
                    750:   multinomial logistic model, is clear when the delay between waves is not
                    751:   identical for each individual. Also, if a individual missed an
                    752:   intermediate interview, the information is lost, but taken into
                    753:   account using an interpolation or extrapolation.  
                    754: 
                    755:   hPijx is the probability to be observed in state i at age x+h
                    756:   conditional to the observed state i at age x. The delay 'h' can be
                    757:   split into an exact number (nh*stepm) of unobserved intermediate
                    758:   states. This elementary transition (by month, quarter,
                    759:   semester or year) is modelled as a multinomial logistic.  The hPx
                    760:   matrix is simply the matrix product of nh*stepm elementary matrices
                    761:   and the contribution of each individual to the likelihood is simply
                    762:   hPijx.
                    763: 
                    764:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   765:   of the life expectancies. It also computes the period (stable) prevalence.
                    766: 
                    767: Back prevalence and projections:
1.227     brouard   768: 
                    769:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    770:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    771:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    772:    mobilavproj)
                    773: 
                    774:     Computes the back prevalence limit for any combination of
                    775:     covariate values k at any age between ageminpar and agemaxpar and
                    776:     returns it in **bprlim. In the loops,
                    777: 
                    778:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    779:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    780: 
                    781:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   782:    Computes for any combination of covariates k and any age between bage and fage 
                    783:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    784:                        oldm=oldms;savm=savms;
1.227     brouard   785: 
                    786:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);
1.218     brouard   787:      Computes the transition matrix starting at age 'age' over
                    788:      'nhstepm*hstepm*stepm' months (i.e. until
                    789:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   790:      nhstepm*hstepm matrices. 
                    791: 
                    792:      Returns p3mat[i][j][h] after calling
                    793:      p3mat[i][j][h]=matprod2(newm,
                    794:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    795:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    796:      oldm);
1.226     brouard   797: 
                    798: Important routines
                    799: 
                    800: - func (or funcone), computes logit (pij) distinguishing
                    801:   o fixed variables (single or product dummies or quantitative);
                    802:   o varying variables by:
                    803:    (1) wave (single, product dummies, quantitative), 
                    804:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    805:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    806:        % varying dummy (not done) or quantitative (not done);
                    807: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    808:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    809: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    810:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    811:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   812: 
1.226     brouard   813: 
                    814:   
1.133     brouard   815:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    816:            Institut national d'études démographiques, Paris.
1.126     brouard   817:   This software have been partly granted by Euro-REVES, a concerted action
                    818:   from the European Union.
                    819:   It is copyrighted identically to a GNU software product, ie programme and
                    820:   software can be distributed freely for non commercial use. Latest version
                    821:   can be accessed at http://euroreves.ined.fr/imach .
                    822: 
                    823:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    824:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    825:   
                    826:   **********************************************************************/
                    827: /*
                    828:   main
                    829:   read parameterfile
                    830:   read datafile
                    831:   concatwav
                    832:   freqsummary
                    833:   if (mle >= 1)
                    834:     mlikeli
                    835:   print results files
                    836:   if mle==1 
                    837:      computes hessian
                    838:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    839:       begin-prev-date,...
                    840:   open gnuplot file
                    841:   open html file
1.145     brouard   842:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    843:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    844:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    845:     freexexit2 possible for memory heap.
                    846: 
                    847:   h Pij x                         | pij_nom  ficrestpij
                    848:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    849:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    850:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    851: 
                    852:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    853:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    854:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    855:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    856:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    857: 
1.126     brouard   858:   forecasting if prevfcast==1 prevforecast call prevalence()
                    859:   health expectancies
                    860:   Variance-covariance of DFLE
                    861:   prevalence()
                    862:    movingaverage()
                    863:   varevsij() 
                    864:   if popbased==1 varevsij(,popbased)
                    865:   total life expectancies
                    866:   Variance of period (stable) prevalence
                    867:  end
                    868: */
                    869: 
1.187     brouard   870: /* #define DEBUG */
                    871: /* #define DEBUGBRENT */
1.203     brouard   872: /* #define DEBUGLINMIN */
                    873: /* #define DEBUGHESS */
                    874: #define DEBUGHESSIJ
1.224     brouard   875: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   876: #define POWELL /* Instead of NLOPT */
1.224     brouard   877: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   878: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    879: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   880: 
                    881: #include <math.h>
                    882: #include <stdio.h>
                    883: #include <stdlib.h>
                    884: #include <string.h>
1.226     brouard   885: #include <ctype.h>
1.159     brouard   886: 
                    887: #ifdef _WIN32
                    888: #include <io.h>
1.172     brouard   889: #include <windows.h>
                    890: #include <tchar.h>
1.159     brouard   891: #else
1.126     brouard   892: #include <unistd.h>
1.159     brouard   893: #endif
1.126     brouard   894: 
                    895: #include <limits.h>
                    896: #include <sys/types.h>
1.171     brouard   897: 
                    898: #if defined(__GNUC__)
                    899: #include <sys/utsname.h> /* Doesn't work on Windows */
                    900: #endif
                    901: 
1.126     brouard   902: #include <sys/stat.h>
                    903: #include <errno.h>
1.159     brouard   904: /* extern int errno; */
1.126     brouard   905: 
1.157     brouard   906: /* #ifdef LINUX */
                    907: /* #include <time.h> */
                    908: /* #include "timeval.h" */
                    909: /* #else */
                    910: /* #include <sys/time.h> */
                    911: /* #endif */
                    912: 
1.126     brouard   913: #include <time.h>
                    914: 
1.136     brouard   915: #ifdef GSL
                    916: #include <gsl/gsl_errno.h>
                    917: #include <gsl/gsl_multimin.h>
                    918: #endif
                    919: 
1.167     brouard   920: 
1.162     brouard   921: #ifdef NLOPT
                    922: #include <nlopt.h>
                    923: typedef struct {
                    924:   double (* function)(double [] );
                    925: } myfunc_data ;
                    926: #endif
                    927: 
1.126     brouard   928: /* #include <libintl.h> */
                    929: /* #define _(String) gettext (String) */
                    930: 
1.251     brouard   931: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   932: 
                    933: #define GNUPLOTPROGRAM "gnuplot"
                    934: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    935: #define FILENAMELENGTH 132
                    936: 
                    937: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    938: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    939: 
1.144     brouard   940: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    941: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   942: 
                    943: #define NINTERVMAX 8
1.144     brouard   944: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    945: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    946: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   947: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   948: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    949: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   950: #define MAXN 20000
1.144     brouard   951: #define YEARM 12. /**< Number of months per year */
1.218     brouard   952: /* #define AGESUP 130 */
                    953: #define AGESUP 150
                    954: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard   955: #define AGEBASE 40
1.194     brouard   956: #define AGEOVERFLOW 1.e20
1.164     brouard   957: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard   958: #ifdef _WIN32
                    959: #define DIRSEPARATOR '\\'
                    960: #define CHARSEPARATOR "\\"
                    961: #define ODIRSEPARATOR '/'
                    962: #else
1.126     brouard   963: #define DIRSEPARATOR '/'
                    964: #define CHARSEPARATOR "/"
                    965: #define ODIRSEPARATOR '\\'
                    966: #endif
                    967: 
1.256   ! brouard   968: /* $Id: imach.c,v 1.255 2017/03/08 16:02:28 brouard Exp $ */
1.126     brouard   969: /* $State: Exp $ */
1.196     brouard   970: #include "version.h"
                    971: char version[]=__IMACH_VERSION__;
1.224     brouard   972: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.256   ! brouard   973: char fullversion[]="$Revision: 1.255 $ $Date: 2017/03/08 16:02:28 $"; 
1.126     brouard   974: char strstart[80];
                    975: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard   976: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard   977: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard   978: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                    979: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                    980: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard   981: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                    982: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard   983: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                    984: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                    985: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard   986: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                    987: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard   988: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard   989: int nsd=0; /**< Total number of single dummy variables (output) */
                    990: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard   991: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard   992: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard   993: int ntveff=0; /**< ntveff number of effective time varying variables */
                    994: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard   995: int cptcov=0; /* Working variable */
1.218     brouard   996: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard   997: int npar=NPARMAX;
                    998: int nlstate=2; /* Number of live states */
                    999: int ndeath=1; /* Number of dead states */
1.130     brouard  1000: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1001: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1002: int popbased=0;
                   1003: 
                   1004: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1005: int maxwav=0; /* Maxim number of waves */
                   1006: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1007: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1008: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1009:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1010: int mle=1, weightopt=0;
1.126     brouard  1011: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1012: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1013: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1014:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1015: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1016: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1017: 
1.130     brouard  1018: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1019: double **matprod2(); /* test */
1.126     brouard  1020: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1021: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1022: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1023: 
1.136     brouard  1024: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1025: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1026: FILE *ficlog, *ficrespow;
1.130     brouard  1027: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1028: double fretone; /* Only one call to likelihood */
1.130     brouard  1029: long ipmx=0; /* Number of contributions */
1.126     brouard  1030: double sw; /* Sum of weights */
                   1031: char filerespow[FILENAMELENGTH];
                   1032: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1033: FILE *ficresilk;
                   1034: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1035: FILE *ficresprobmorprev;
                   1036: FILE *fichtm, *fichtmcov; /* Html File */
                   1037: FILE *ficreseij;
                   1038: char filerese[FILENAMELENGTH];
                   1039: FILE *ficresstdeij;
                   1040: char fileresstde[FILENAMELENGTH];
                   1041: FILE *ficrescveij;
                   1042: char filerescve[FILENAMELENGTH];
                   1043: FILE  *ficresvij;
                   1044: char fileresv[FILENAMELENGTH];
                   1045: FILE  *ficresvpl;
                   1046: char fileresvpl[FILENAMELENGTH];
                   1047: char title[MAXLINE];
1.234     brouard  1048: char model[MAXLINE]; /**< The model line */
1.217     brouard  1049: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1050: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1051: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1052: char command[FILENAMELENGTH];
                   1053: int  outcmd=0;
                   1054: 
1.217     brouard  1055: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1056: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1057: char filelog[FILENAMELENGTH]; /* Log file */
                   1058: char filerest[FILENAMELENGTH];
                   1059: char fileregp[FILENAMELENGTH];
                   1060: char popfile[FILENAMELENGTH];
                   1061: 
                   1062: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1063: 
1.157     brouard  1064: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1065: /* struct timezone tzp; */
                   1066: /* extern int gettimeofday(); */
                   1067: struct tm tml, *gmtime(), *localtime();
                   1068: 
                   1069: extern time_t time();
                   1070: 
                   1071: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1072: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1073: struct tm tm;
                   1074: 
1.126     brouard  1075: char strcurr[80], strfor[80];
                   1076: 
                   1077: char *endptr;
                   1078: long lval;
                   1079: double dval;
                   1080: 
                   1081: #define NR_END 1
                   1082: #define FREE_ARG char*
                   1083: #define FTOL 1.0e-10
                   1084: 
                   1085: #define NRANSI 
1.240     brouard  1086: #define ITMAX 200
                   1087: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1088: 
                   1089: #define TOL 2.0e-4 
                   1090: 
                   1091: #define CGOLD 0.3819660 
                   1092: #define ZEPS 1.0e-10 
                   1093: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1094: 
                   1095: #define GOLD 1.618034 
                   1096: #define GLIMIT 100.0 
                   1097: #define TINY 1.0e-20 
                   1098: 
                   1099: static double maxarg1,maxarg2;
                   1100: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1101: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1102:   
                   1103: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1104: #define rint(a) floor(a+0.5)
1.166     brouard  1105: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1106: #define mytinydouble 1.0e-16
1.166     brouard  1107: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1108: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1109: /* static double dsqrarg; */
                   1110: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1111: static double sqrarg;
                   1112: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1113: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1114: int agegomp= AGEGOMP;
                   1115: 
                   1116: int imx; 
                   1117: int stepm=1;
                   1118: /* Stepm, step in month: minimum step interpolation*/
                   1119: 
                   1120: int estepm;
                   1121: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1122: 
                   1123: int m,nb;
                   1124: long *num;
1.197     brouard  1125: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1126: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1127:                   covariate for which somebody answered excluding 
                   1128:                   undefined. Usually 2: 0 and 1. */
                   1129: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1130:                             covariate for which somebody answered including 
                   1131:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1132: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1133: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1134: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1135: double *ageexmed,*agecens;
                   1136: double dateintmean=0;
                   1137: 
                   1138: double *weight;
                   1139: int **s; /* Status */
1.141     brouard  1140: double *agedc;
1.145     brouard  1141: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1142:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1143:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.225     brouard  1144: double **coqvar; /* Fixed quantitative covariate iqv */
                   1145: double ***cotvar; /* Time varying covariate itv */
                   1146: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1147: double  idx; 
                   1148: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1149: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1150: /*k          1  2   3   4     5    6    7     8    9 */
                   1151: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1152: /* Tndvar[k]    1   2   3               4          5 */
                   1153: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1154: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1155: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1156: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1157: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1158: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1159: /* Tprod[i]=k           4               7            */
                   1160: /* Tage[i]=k                  5               8      */
                   1161: /* */
                   1162: /* Type                    */
                   1163: /* V         1  2  3  4  5 */
                   1164: /*           F  F  V  V  V */
                   1165: /*           D  Q  D  D  Q */
                   1166: /*                         */
                   1167: int *TvarsD;
                   1168: int *TvarsDind;
                   1169: int *TvarsQ;
                   1170: int *TvarsQind;
                   1171: 
1.235     brouard  1172: #define MAXRESULTLINES 10
                   1173: int nresult=0;
                   1174: int TKresult[MAXRESULTLINES];
1.237     brouard  1175: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1176: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1177: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1178: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1179: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1180: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1181: 
1.234     brouard  1182: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1183: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1184: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1185: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1186: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1187: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1188: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1189: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1190: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1191: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1192: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1193: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1194: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1195: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1196: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1197: 
1.230     brouard  1198: int *Tvarsel; /**< Selected covariates for output */
                   1199: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1200: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1201: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1202: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1203: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1204: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1205: int *Tage;
1.227     brouard  1206: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1207: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1208: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1209: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1210: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1211: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1212: int **Tvard;
                   1213: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1214: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1215: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1216:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1217:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1218: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1219: double *lsurv, *lpop, *tpop;
                   1220: 
1.231     brouard  1221: #define FD 1; /* Fixed dummy covariate */
                   1222: #define FQ 2; /* Fixed quantitative covariate */
                   1223: #define FP 3; /* Fixed product covariate */
                   1224: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1225: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1226: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1227: #define VD 10; /* Varying dummy covariate */
                   1228: #define VQ 11; /* Varying quantitative covariate */
                   1229: #define VP 12; /* Varying product covariate */
                   1230: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1231: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1232: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1233: #define APFD 16; /* Age product * fixed dummy covariate */
                   1234: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1235: #define APVD 18; /* Age product * varying dummy covariate */
                   1236: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1237: 
                   1238: #define FTYPE 1; /* Fixed covariate */
                   1239: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1240: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1241: 
                   1242: struct kmodel{
                   1243:        int maintype; /* main type */
                   1244:        int subtype; /* subtype */
                   1245: };
                   1246: struct kmodel modell[NCOVMAX];
                   1247: 
1.143     brouard  1248: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1249: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1250: 
                   1251: /**************** split *************************/
                   1252: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1253: {
                   1254:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1255:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1256:   */ 
                   1257:   char *ss;                            /* pointer */
1.186     brouard  1258:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1259: 
                   1260:   l1 = strlen(path );                  /* length of path */
                   1261:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1262:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1263:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1264:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1265:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1266:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1267:     /* get current working directory */
                   1268:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1269: #ifdef WIN32
                   1270:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1271: #else
                   1272:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1273: #endif
1.126     brouard  1274:       return( GLOCK_ERROR_GETCWD );
                   1275:     }
                   1276:     /* got dirc from getcwd*/
                   1277:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1278:   } else {                             /* strip directory from path */
1.126     brouard  1279:     ss++;                              /* after this, the filename */
                   1280:     l2 = strlen( ss );                 /* length of filename */
                   1281:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1282:     strcpy( name, ss );                /* save file name */
                   1283:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1284:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1285:     printf(" DIRC2 = %s \n",dirc);
                   1286:   }
                   1287:   /* We add a separator at the end of dirc if not exists */
                   1288:   l1 = strlen( dirc );                 /* length of directory */
                   1289:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1290:     dirc[l1] =  DIRSEPARATOR;
                   1291:     dirc[l1+1] = 0; 
                   1292:     printf(" DIRC3 = %s \n",dirc);
                   1293:   }
                   1294:   ss = strrchr( name, '.' );           /* find last / */
                   1295:   if (ss >0){
                   1296:     ss++;
                   1297:     strcpy(ext,ss);                    /* save extension */
                   1298:     l1= strlen( name);
                   1299:     l2= strlen(ss)+1;
                   1300:     strncpy( finame, name, l1-l2);
                   1301:     finame[l1-l2]= 0;
                   1302:   }
                   1303: 
                   1304:   return( 0 );                         /* we're done */
                   1305: }
                   1306: 
                   1307: 
                   1308: /******************************************/
                   1309: 
                   1310: void replace_back_to_slash(char *s, char*t)
                   1311: {
                   1312:   int i;
                   1313:   int lg=0;
                   1314:   i=0;
                   1315:   lg=strlen(t);
                   1316:   for(i=0; i<= lg; i++) {
                   1317:     (s[i] = t[i]);
                   1318:     if (t[i]== '\\') s[i]='/';
                   1319:   }
                   1320: }
                   1321: 
1.132     brouard  1322: char *trimbb(char *out, char *in)
1.137     brouard  1323: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1324:   char *s;
                   1325:   s=out;
                   1326:   while (*in != '\0'){
1.137     brouard  1327:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1328:       in++;
                   1329:     }
                   1330:     *out++ = *in++;
                   1331:   }
                   1332:   *out='\0';
                   1333:   return s;
                   1334: }
                   1335: 
1.187     brouard  1336: /* char *substrchaine(char *out, char *in, char *chain) */
                   1337: /* { */
                   1338: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1339: /*   char *s, *t; */
                   1340: /*   t=in;s=out; */
                   1341: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1342: /*     *out++ = *in++; */
                   1343: /*   } */
                   1344: 
                   1345: /*   /\* *in matches *chain *\/ */
                   1346: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1347: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1348: /*   } */
                   1349: /*   in--; chain--; */
                   1350: /*   while ( (*in != '\0')){ */
                   1351: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1352: /*     *out++ = *in++; */
                   1353: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1354: /*   } */
                   1355: /*   *out='\0'; */
                   1356: /*   out=s; */
                   1357: /*   return out; */
                   1358: /* } */
                   1359: char *substrchaine(char *out, char *in, char *chain)
                   1360: {
                   1361:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1362:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1363: 
                   1364:   char *strloc;
                   1365: 
                   1366:   strcpy (out, in); 
                   1367:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1368:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1369:   if(strloc != NULL){ 
                   1370:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1371:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1372:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1373:   }
                   1374:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1375:   return out;
                   1376: }
                   1377: 
                   1378: 
1.145     brouard  1379: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1380: {
1.187     brouard  1381:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1382:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1383:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1384:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1385:   */
1.160     brouard  1386:   char *s, *t;
1.145     brouard  1387:   t=in;s=in;
                   1388:   while ((*in != occ) && (*in != '\0')){
                   1389:     *alocc++ = *in++;
                   1390:   }
                   1391:   if( *in == occ){
                   1392:     *(alocc)='\0';
                   1393:     s=++in;
                   1394:   }
                   1395:  
                   1396:   if (s == t) {/* occ not found */
                   1397:     *(alocc-(in-s))='\0';
                   1398:     in=s;
                   1399:   }
                   1400:   while ( *in != '\0'){
                   1401:     *blocc++ = *in++;
                   1402:   }
                   1403: 
                   1404:   *blocc='\0';
                   1405:   return t;
                   1406: }
1.137     brouard  1407: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1408: {
1.187     brouard  1409:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1410:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1411:      gives blocc="abcdef2ghi" and alocc="j".
                   1412:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1413:   */
                   1414:   char *s, *t;
                   1415:   t=in;s=in;
                   1416:   while (*in != '\0'){
                   1417:     while( *in == occ){
                   1418:       *blocc++ = *in++;
                   1419:       s=in;
                   1420:     }
                   1421:     *blocc++ = *in++;
                   1422:   }
                   1423:   if (s == t) /* occ not found */
                   1424:     *(blocc-(in-s))='\0';
                   1425:   else
                   1426:     *(blocc-(in-s)-1)='\0';
                   1427:   in=s;
                   1428:   while ( *in != '\0'){
                   1429:     *alocc++ = *in++;
                   1430:   }
                   1431: 
                   1432:   *alocc='\0';
                   1433:   return s;
                   1434: }
                   1435: 
1.126     brouard  1436: int nbocc(char *s, char occ)
                   1437: {
                   1438:   int i,j=0;
                   1439:   int lg=20;
                   1440:   i=0;
                   1441:   lg=strlen(s);
                   1442:   for(i=0; i<= lg; i++) {
1.234     brouard  1443:     if  (s[i] == occ ) j++;
1.126     brouard  1444:   }
                   1445:   return j;
                   1446: }
                   1447: 
1.137     brouard  1448: /* void cutv(char *u,char *v, char*t, char occ) */
                   1449: /* { */
                   1450: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1451: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1452: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1453: /*   int i,lg,j,p=0; */
                   1454: /*   i=0; */
                   1455: /*   lg=strlen(t); */
                   1456: /*   for(j=0; j<=lg-1; j++) { */
                   1457: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1458: /*   } */
1.126     brouard  1459: 
1.137     brouard  1460: /*   for(j=0; j<p; j++) { */
                   1461: /*     (u[j] = t[j]); */
                   1462: /*   } */
                   1463: /*      u[p]='\0'; */
1.126     brouard  1464: 
1.137     brouard  1465: /*    for(j=0; j<= lg; j++) { */
                   1466: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1467: /*   } */
                   1468: /* } */
1.126     brouard  1469: 
1.160     brouard  1470: #ifdef _WIN32
                   1471: char * strsep(char **pp, const char *delim)
                   1472: {
                   1473:   char *p, *q;
                   1474:          
                   1475:   if ((p = *pp) == NULL)
                   1476:     return 0;
                   1477:   if ((q = strpbrk (p, delim)) != NULL)
                   1478:   {
                   1479:     *pp = q + 1;
                   1480:     *q = '\0';
                   1481:   }
                   1482:   else
                   1483:     *pp = 0;
                   1484:   return p;
                   1485: }
                   1486: #endif
                   1487: 
1.126     brouard  1488: /********************** nrerror ********************/
                   1489: 
                   1490: void nrerror(char error_text[])
                   1491: {
                   1492:   fprintf(stderr,"ERREUR ...\n");
                   1493:   fprintf(stderr,"%s\n",error_text);
                   1494:   exit(EXIT_FAILURE);
                   1495: }
                   1496: /*********************** vector *******************/
                   1497: double *vector(int nl, int nh)
                   1498: {
                   1499:   double *v;
                   1500:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1501:   if (!v) nrerror("allocation failure in vector");
                   1502:   return v-nl+NR_END;
                   1503: }
                   1504: 
                   1505: /************************ free vector ******************/
                   1506: void free_vector(double*v, int nl, int nh)
                   1507: {
                   1508:   free((FREE_ARG)(v+nl-NR_END));
                   1509: }
                   1510: 
                   1511: /************************ivector *******************************/
                   1512: int *ivector(long nl,long nh)
                   1513: {
                   1514:   int *v;
                   1515:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1516:   if (!v) nrerror("allocation failure in ivector");
                   1517:   return v-nl+NR_END;
                   1518: }
                   1519: 
                   1520: /******************free ivector **************************/
                   1521: void free_ivector(int *v, long nl, long nh)
                   1522: {
                   1523:   free((FREE_ARG)(v+nl-NR_END));
                   1524: }
                   1525: 
                   1526: /************************lvector *******************************/
                   1527: long *lvector(long nl,long nh)
                   1528: {
                   1529:   long *v;
                   1530:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1531:   if (!v) nrerror("allocation failure in ivector");
                   1532:   return v-nl+NR_END;
                   1533: }
                   1534: 
                   1535: /******************free lvector **************************/
                   1536: void free_lvector(long *v, long nl, long nh)
                   1537: {
                   1538:   free((FREE_ARG)(v+nl-NR_END));
                   1539: }
                   1540: 
                   1541: /******************* imatrix *******************************/
                   1542: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1543:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1544: { 
                   1545:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1546:   int **m; 
                   1547:   
                   1548:   /* allocate pointers to rows */ 
                   1549:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1550:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1551:   m += NR_END; 
                   1552:   m -= nrl; 
                   1553:   
                   1554:   
                   1555:   /* allocate rows and set pointers to them */ 
                   1556:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1557:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1558:   m[nrl] += NR_END; 
                   1559:   m[nrl] -= ncl; 
                   1560:   
                   1561:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1562:   
                   1563:   /* return pointer to array of pointers to rows */ 
                   1564:   return m; 
                   1565: } 
                   1566: 
                   1567: /****************** free_imatrix *************************/
                   1568: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1569:       int **m;
                   1570:       long nch,ncl,nrh,nrl; 
                   1571:      /* free an int matrix allocated by imatrix() */ 
                   1572: { 
                   1573:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1574:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1575: } 
                   1576: 
                   1577: /******************* matrix *******************************/
                   1578: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1579: {
                   1580:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1581:   double **m;
                   1582: 
                   1583:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1584:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1585:   m += NR_END;
                   1586:   m -= nrl;
                   1587: 
                   1588:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1589:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1590:   m[nrl] += NR_END;
                   1591:   m[nrl] -= ncl;
                   1592: 
                   1593:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1594:   return m;
1.145     brouard  1595:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1596: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1597: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1598:    */
                   1599: }
                   1600: 
                   1601: /*************************free matrix ************************/
                   1602: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1603: {
                   1604:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1605:   free((FREE_ARG)(m+nrl-NR_END));
                   1606: }
                   1607: 
                   1608: /******************* ma3x *******************************/
                   1609: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1610: {
                   1611:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1612:   double ***m;
                   1613: 
                   1614:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1615:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1616:   m += NR_END;
                   1617:   m -= nrl;
                   1618: 
                   1619:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1620:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1621:   m[nrl] += NR_END;
                   1622:   m[nrl] -= ncl;
                   1623: 
                   1624:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1625: 
                   1626:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1627:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1628:   m[nrl][ncl] += NR_END;
                   1629:   m[nrl][ncl] -= nll;
                   1630:   for (j=ncl+1; j<=nch; j++) 
                   1631:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1632:   
                   1633:   for (i=nrl+1; i<=nrh; i++) {
                   1634:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1635:     for (j=ncl+1; j<=nch; j++) 
                   1636:       m[i][j]=m[i][j-1]+nlay;
                   1637:   }
                   1638:   return m; 
                   1639:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1640:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1641:   */
                   1642: }
                   1643: 
                   1644: /*************************free ma3x ************************/
                   1645: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1646: {
                   1647:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1648:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1649:   free((FREE_ARG)(m+nrl-NR_END));
                   1650: }
                   1651: 
                   1652: /*************** function subdirf ***********/
                   1653: char *subdirf(char fileres[])
                   1654: {
                   1655:   /* Caution optionfilefiname is hidden */
                   1656:   strcpy(tmpout,optionfilefiname);
                   1657:   strcat(tmpout,"/"); /* Add to the right */
                   1658:   strcat(tmpout,fileres);
                   1659:   return tmpout;
                   1660: }
                   1661: 
                   1662: /*************** function subdirf2 ***********/
                   1663: char *subdirf2(char fileres[], char *preop)
                   1664: {
                   1665:   
                   1666:   /* Caution optionfilefiname is hidden */
                   1667:   strcpy(tmpout,optionfilefiname);
                   1668:   strcat(tmpout,"/");
                   1669:   strcat(tmpout,preop);
                   1670:   strcat(tmpout,fileres);
                   1671:   return tmpout;
                   1672: }
                   1673: 
                   1674: /*************** function subdirf3 ***********/
                   1675: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1676: {
                   1677:   
                   1678:   /* Caution optionfilefiname is hidden */
                   1679:   strcpy(tmpout,optionfilefiname);
                   1680:   strcat(tmpout,"/");
                   1681:   strcat(tmpout,preop);
                   1682:   strcat(tmpout,preop2);
                   1683:   strcat(tmpout,fileres);
                   1684:   return tmpout;
                   1685: }
1.213     brouard  1686:  
                   1687: /*************** function subdirfext ***********/
                   1688: char *subdirfext(char fileres[], char *preop, char *postop)
                   1689: {
                   1690:   
                   1691:   strcpy(tmpout,preop);
                   1692:   strcat(tmpout,fileres);
                   1693:   strcat(tmpout,postop);
                   1694:   return tmpout;
                   1695: }
1.126     brouard  1696: 
1.213     brouard  1697: /*************** function subdirfext3 ***********/
                   1698: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1699: {
                   1700:   
                   1701:   /* Caution optionfilefiname is hidden */
                   1702:   strcpy(tmpout,optionfilefiname);
                   1703:   strcat(tmpout,"/");
                   1704:   strcat(tmpout,preop);
                   1705:   strcat(tmpout,fileres);
                   1706:   strcat(tmpout,postop);
                   1707:   return tmpout;
                   1708: }
                   1709:  
1.162     brouard  1710: char *asc_diff_time(long time_sec, char ascdiff[])
                   1711: {
                   1712:   long sec_left, days, hours, minutes;
                   1713:   days = (time_sec) / (60*60*24);
                   1714:   sec_left = (time_sec) % (60*60*24);
                   1715:   hours = (sec_left) / (60*60) ;
                   1716:   sec_left = (sec_left) %(60*60);
                   1717:   minutes = (sec_left) /60;
                   1718:   sec_left = (sec_left) % (60);
                   1719:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1720:   return ascdiff;
                   1721: }
                   1722: 
1.126     brouard  1723: /***************** f1dim *************************/
                   1724: extern int ncom; 
                   1725: extern double *pcom,*xicom;
                   1726: extern double (*nrfunc)(double []); 
                   1727:  
                   1728: double f1dim(double x) 
                   1729: { 
                   1730:   int j; 
                   1731:   double f;
                   1732:   double *xt; 
                   1733:  
                   1734:   xt=vector(1,ncom); 
                   1735:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1736:   f=(*nrfunc)(xt); 
                   1737:   free_vector(xt,1,ncom); 
                   1738:   return f; 
                   1739: } 
                   1740: 
                   1741: /*****************brent *************************/
                   1742: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1743: {
                   1744:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1745:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1746:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1747:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1748:    * returned function value. 
                   1749:   */
1.126     brouard  1750:   int iter; 
                   1751:   double a,b,d,etemp;
1.159     brouard  1752:   double fu=0,fv,fw,fx;
1.164     brouard  1753:   double ftemp=0.;
1.126     brouard  1754:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1755:   double e=0.0; 
                   1756:  
                   1757:   a=(ax < cx ? ax : cx); 
                   1758:   b=(ax > cx ? ax : cx); 
                   1759:   x=w=v=bx; 
                   1760:   fw=fv=fx=(*f)(x); 
                   1761:   for (iter=1;iter<=ITMAX;iter++) { 
                   1762:     xm=0.5*(a+b); 
                   1763:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1764:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1765:     printf(".");fflush(stdout);
                   1766:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1767: #ifdef DEBUGBRENT
1.126     brouard  1768:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1769:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1770:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1771: #endif
                   1772:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1773:       *xmin=x; 
                   1774:       return fx; 
                   1775:     } 
                   1776:     ftemp=fu;
                   1777:     if (fabs(e) > tol1) { 
                   1778:       r=(x-w)*(fx-fv); 
                   1779:       q=(x-v)*(fx-fw); 
                   1780:       p=(x-v)*q-(x-w)*r; 
                   1781:       q=2.0*(q-r); 
                   1782:       if (q > 0.0) p = -p; 
                   1783:       q=fabs(q); 
                   1784:       etemp=e; 
                   1785:       e=d; 
                   1786:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1787:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1788:       else { 
1.224     brouard  1789:                                d=p/q; 
                   1790:                                u=x+d; 
                   1791:                                if (u-a < tol2 || b-u < tol2) 
                   1792:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1793:       } 
                   1794:     } else { 
                   1795:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1796:     } 
                   1797:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1798:     fu=(*f)(u); 
                   1799:     if (fu <= fx) { 
                   1800:       if (u >= x) a=x; else b=x; 
                   1801:       SHFT(v,w,x,u) 
1.183     brouard  1802:       SHFT(fv,fw,fx,fu) 
                   1803:     } else { 
                   1804:       if (u < x) a=u; else b=u; 
                   1805:       if (fu <= fw || w == x) { 
1.224     brouard  1806:                                v=w; 
                   1807:                                w=u; 
                   1808:                                fv=fw; 
                   1809:                                fw=fu; 
1.183     brouard  1810:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1811:                                v=u; 
                   1812:                                fv=fu; 
1.183     brouard  1813:       } 
                   1814:     } 
1.126     brouard  1815:   } 
                   1816:   nrerror("Too many iterations in brent"); 
                   1817:   *xmin=x; 
                   1818:   return fx; 
                   1819: } 
                   1820: 
                   1821: /****************** mnbrak ***********************/
                   1822: 
                   1823: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1824:            double (*func)(double)) 
1.183     brouard  1825: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1826: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1827: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1828: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1829:    */
1.126     brouard  1830:   double ulim,u,r,q, dum;
                   1831:   double fu; 
1.187     brouard  1832: 
                   1833:   double scale=10.;
                   1834:   int iterscale=0;
                   1835: 
                   1836:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1837:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1838: 
                   1839: 
                   1840:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1841:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1842:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1843:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1844:   /* } */
                   1845: 
1.126     brouard  1846:   if (*fb > *fa) { 
                   1847:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1848:     SHFT(dum,*fb,*fa,dum) 
                   1849:   } 
1.126     brouard  1850:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1851:   *fc=(*func)(*cx); 
1.183     brouard  1852: #ifdef DEBUG
1.224     brouard  1853:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1854:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1855: #endif
1.224     brouard  1856:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1857:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1858:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1859:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1860:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1861:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1862:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1863:       fu=(*func)(u); 
1.163     brouard  1864: #ifdef DEBUG
                   1865:       /* f(x)=A(x-u)**2+f(u) */
                   1866:       double A, fparabu; 
                   1867:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1868:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1869:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1870:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1871:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1872:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1873:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1874:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1875: #endif 
1.184     brouard  1876: #ifdef MNBRAKORIGINAL
1.183     brouard  1877: #else
1.191     brouard  1878: /*       if (fu > *fc) { */
                   1879: /* #ifdef DEBUG */
                   1880: /*       printf("mnbrak4  fu > fc \n"); */
                   1881: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1882: /* #endif */
                   1883: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1884: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1885: /*     dum=u; /\* Shifting c and u *\/ */
                   1886: /*     u = *cx; */
                   1887: /*     *cx = dum; */
                   1888: /*     dum = fu; */
                   1889: /*     fu = *fc; */
                   1890: /*     *fc =dum; */
                   1891: /*       } else { /\* end *\/ */
                   1892: /* #ifdef DEBUG */
                   1893: /*       printf("mnbrak3  fu < fc \n"); */
                   1894: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1895: /* #endif */
                   1896: /*     dum=u; /\* Shifting c and u *\/ */
                   1897: /*     u = *cx; */
                   1898: /*     *cx = dum; */
                   1899: /*     dum = fu; */
                   1900: /*     fu = *fc; */
                   1901: /*     *fc =dum; */
                   1902: /*       } */
1.224     brouard  1903: #ifdef DEBUGMNBRAK
                   1904:                 double A, fparabu; 
                   1905:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1906:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1907:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1908:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1909: #endif
1.191     brouard  1910:       dum=u; /* Shifting c and u */
                   1911:       u = *cx;
                   1912:       *cx = dum;
                   1913:       dum = fu;
                   1914:       fu = *fc;
                   1915:       *fc =dum;
1.183     brouard  1916: #endif
1.162     brouard  1917:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1918: #ifdef DEBUG
1.224     brouard  1919:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1920:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1921: #endif
1.126     brouard  1922:       fu=(*func)(u); 
                   1923:       if (fu < *fc) { 
1.183     brouard  1924: #ifdef DEBUG
1.224     brouard  1925:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1926:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1927: #endif
                   1928:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1929:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1930: #ifdef DEBUG
                   1931:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1932: #endif
                   1933:       } 
1.162     brouard  1934:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1935: #ifdef DEBUG
1.224     brouard  1936:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1937:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1938: #endif
1.126     brouard  1939:       u=ulim; 
                   1940:       fu=(*func)(u); 
1.183     brouard  1941:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1942: #ifdef DEBUG
1.224     brouard  1943:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1944:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1945: #endif
1.126     brouard  1946:       u=(*cx)+GOLD*(*cx-*bx); 
                   1947:       fu=(*func)(u); 
1.224     brouard  1948: #ifdef DEBUG
                   1949:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1950:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1951: #endif
1.183     brouard  1952:     } /* end tests */
1.126     brouard  1953:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  1954:     SHFT(*fa,*fb,*fc,fu) 
                   1955: #ifdef DEBUG
1.224     brouard  1956:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   1957:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  1958: #endif
                   1959:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  1960: } 
                   1961: 
                   1962: /*************** linmin ************************/
1.162     brouard  1963: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   1964: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   1965: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   1966: the value of func at the returned location p . This is actually all accomplished by calling the
                   1967: routines mnbrak and brent .*/
1.126     brouard  1968: int ncom; 
                   1969: double *pcom,*xicom;
                   1970: double (*nrfunc)(double []); 
                   1971:  
1.224     brouard  1972: #ifdef LINMINORIGINAL
1.126     brouard  1973: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  1974: #else
                   1975: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   1976: #endif
1.126     brouard  1977: { 
                   1978:   double brent(double ax, double bx, double cx, 
                   1979:               double (*f)(double), double tol, double *xmin); 
                   1980:   double f1dim(double x); 
                   1981:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   1982:              double *fc, double (*func)(double)); 
                   1983:   int j; 
                   1984:   double xx,xmin,bx,ax; 
                   1985:   double fx,fb,fa;
1.187     brouard  1986: 
1.203     brouard  1987: #ifdef LINMINORIGINAL
                   1988: #else
                   1989:   double scale=10., axs, xxs; /* Scale added for infinity */
                   1990: #endif
                   1991:   
1.126     brouard  1992:   ncom=n; 
                   1993:   pcom=vector(1,n); 
                   1994:   xicom=vector(1,n); 
                   1995:   nrfunc=func; 
                   1996:   for (j=1;j<=n;j++) { 
                   1997:     pcom[j]=p[j]; 
1.202     brouard  1998:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  1999:   } 
1.187     brouard  2000: 
1.203     brouard  2001: #ifdef LINMINORIGINAL
                   2002:   xx=1.;
                   2003: #else
                   2004:   axs=0.0;
                   2005:   xxs=1.;
                   2006:   do{
                   2007:     xx= xxs;
                   2008: #endif
1.187     brouard  2009:     ax=0.;
                   2010:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2011:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2012:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2013:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2014:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2015:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2016:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2017: #ifdef LINMINORIGINAL
                   2018: #else
                   2019:     if (fx != fx){
1.224     brouard  2020:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2021:                        printf("|");
                   2022:                        fprintf(ficlog,"|");
1.203     brouard  2023: #ifdef DEBUGLINMIN
1.224     brouard  2024:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2025: #endif
                   2026:     }
1.224     brouard  2027:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2028: #endif
                   2029:   
1.191     brouard  2030: #ifdef DEBUGLINMIN
                   2031:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2032:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2033: #endif
1.224     brouard  2034: #ifdef LINMINORIGINAL
                   2035: #else
                   2036:        if(fb == fx){ /* Flat function in the direction */
                   2037:                xmin=xx;
                   2038:     *flat=1;
                   2039:        }else{
                   2040:     *flat=0;
                   2041: #endif
                   2042:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2043:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2044:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2045:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2046:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2047:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2048: #ifdef DEBUG
1.224     brouard  2049:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2050:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2051: #endif
                   2052: #ifdef LINMINORIGINAL
                   2053: #else
                   2054:                        }
1.126     brouard  2055: #endif
1.191     brouard  2056: #ifdef DEBUGLINMIN
                   2057:   printf("linmin end ");
1.202     brouard  2058:   fprintf(ficlog,"linmin end ");
1.191     brouard  2059: #endif
1.126     brouard  2060:   for (j=1;j<=n;j++) { 
1.203     brouard  2061: #ifdef LINMINORIGINAL
                   2062:     xi[j] *= xmin; 
                   2063: #else
                   2064: #ifdef DEBUGLINMIN
                   2065:     if(xxs <1.0)
                   2066:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2067: #endif
                   2068:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2069: #ifdef DEBUGLINMIN
                   2070:     if(xxs <1.0)
                   2071:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2072: #endif
                   2073: #endif
1.187     brouard  2074:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2075:   } 
1.191     brouard  2076: #ifdef DEBUGLINMIN
1.203     brouard  2077:   printf("\n");
1.191     brouard  2078:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2079:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2080:   for (j=1;j<=n;j++) { 
1.202     brouard  2081:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2082:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2083:     if(j % ncovmodel == 0){
1.191     brouard  2084:       printf("\n");
1.202     brouard  2085:       fprintf(ficlog,"\n");
                   2086:     }
1.191     brouard  2087:   }
1.203     brouard  2088: #else
1.191     brouard  2089: #endif
1.126     brouard  2090:   free_vector(xicom,1,n); 
                   2091:   free_vector(pcom,1,n); 
                   2092: } 
                   2093: 
                   2094: 
                   2095: /*************** powell ************************/
1.162     brouard  2096: /*
                   2097: Minimization of a function func of n variables. Input consists of an initial starting point
                   2098: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2099: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2100: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2101: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2102: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2103:  */
1.224     brouard  2104: #ifdef LINMINORIGINAL
                   2105: #else
                   2106:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2107:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2108: #endif
1.126     brouard  2109: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2110:            double (*func)(double [])) 
                   2111: { 
1.224     brouard  2112: #ifdef LINMINORIGINAL
                   2113:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2114:              double (*func)(double [])); 
1.224     brouard  2115: #else 
1.241     brouard  2116:  void linmin(double p[], double xi[], int n, double *fret,
                   2117:             double (*func)(double []),int *flat); 
1.224     brouard  2118: #endif
1.239     brouard  2119:  int i,ibig,j,jk,k; 
1.126     brouard  2120:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2121:   double directest;
1.126     brouard  2122:   double fp,fptt;
                   2123:   double *xits;
                   2124:   int niterf, itmp;
1.224     brouard  2125: #ifdef LINMINORIGINAL
                   2126: #else
                   2127: 
                   2128:   flatdir=ivector(1,n); 
                   2129:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2130: #endif
1.126     brouard  2131: 
                   2132:   pt=vector(1,n); 
                   2133:   ptt=vector(1,n); 
                   2134:   xit=vector(1,n); 
                   2135:   xits=vector(1,n); 
                   2136:   *fret=(*func)(p); 
                   2137:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2138:   rcurr_time = time(NULL);  
1.126     brouard  2139:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2140:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2141:     ibig=0; 
                   2142:     del=0.0; 
1.157     brouard  2143:     rlast_time=rcurr_time;
                   2144:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2145:     rcurr_time = time(NULL);  
                   2146:     curr_time = *localtime(&rcurr_time);
                   2147:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2148:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2149: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2150:     for (i=1;i<=n;i++) {
1.126     brouard  2151:       fprintf(ficrespow," %.12lf", p[i]);
                   2152:     }
1.239     brouard  2153:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2154:     printf("\n#model=  1      +     age ");
                   2155:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2156:     if(nagesqr==1){
1.241     brouard  2157:        printf("  + age*age  ");
                   2158:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2159:     }
                   2160:     for(j=1;j <=ncovmodel-2;j++){
                   2161:       if(Typevar[j]==0) {
                   2162:        printf("  +      V%d  ",Tvar[j]);
                   2163:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2164:       }else if(Typevar[j]==1) {
                   2165:        printf("  +    V%d*age ",Tvar[j]);
                   2166:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2167:       }else if(Typevar[j]==2) {
                   2168:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2169:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2170:       }
                   2171:     }
1.126     brouard  2172:     printf("\n");
1.239     brouard  2173: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2174: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2175:     fprintf(ficlog,"\n");
1.239     brouard  2176:     for(i=1,jk=1; i <=nlstate; i++){
                   2177:       for(k=1; k <=(nlstate+ndeath); k++){
                   2178:        if (k != i) {
                   2179:          printf("%d%d ",i,k);
                   2180:          fprintf(ficlog,"%d%d ",i,k);
                   2181:          for(j=1; j <=ncovmodel; j++){
                   2182:            printf("%12.7f ",p[jk]);
                   2183:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2184:            jk++; 
                   2185:          }
                   2186:          printf("\n");
                   2187:          fprintf(ficlog,"\n");
                   2188:        }
                   2189:       }
                   2190:     }
1.241     brouard  2191:     if(*iter <=3 && *iter >1){
1.157     brouard  2192:       tml = *localtime(&rcurr_time);
                   2193:       strcpy(strcurr,asctime(&tml));
                   2194:       rforecast_time=rcurr_time; 
1.126     brouard  2195:       itmp = strlen(strcurr);
                   2196:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2197:        strcurr[itmp-1]='\0';
1.162     brouard  2198:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2199:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2200:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2201:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2202:        forecast_time = *localtime(&rforecast_time);
                   2203:        strcpy(strfor,asctime(&forecast_time));
                   2204:        itmp = strlen(strfor);
                   2205:        if(strfor[itmp-1]=='\n')
                   2206:          strfor[itmp-1]='\0';
                   2207:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2208:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2209:       }
                   2210:     }
1.187     brouard  2211:     for (i=1;i<=n;i++) { /* For each direction i */
                   2212:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2213:       fptt=(*fret); 
                   2214: #ifdef DEBUG
1.203     brouard  2215:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2216:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2217: #endif
1.203     brouard  2218:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2219:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2220: #ifdef LINMINORIGINAL
1.188     brouard  2221:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2222: #else
                   2223:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2224:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2225: #endif
                   2226:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2227:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2228:                                /* because that direction will be replaced unless the gain del is small */
                   2229:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2230:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2231:                                /* with the new direction. */
                   2232:                                del=fabs(fptt-(*fret)); 
                   2233:                                ibig=i; 
1.126     brouard  2234:       } 
                   2235: #ifdef DEBUG
                   2236:       printf("%d %.12e",i,(*fret));
                   2237:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2238:       for (j=1;j<=n;j++) {
1.224     brouard  2239:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2240:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2241:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2242:       }
                   2243:       for(j=1;j<=n;j++) {
1.225     brouard  2244:                                printf(" p(%d)=%.12e",j,p[j]);
                   2245:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2246:       }
                   2247:       printf("\n");
                   2248:       fprintf(ficlog,"\n");
                   2249: #endif
1.187     brouard  2250:     } /* end loop on each direction i */
                   2251:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2252:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2253:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2254:       for(j=1;j<=n;j++) {
1.225     brouard  2255:                                if(flatdir[j] >0){
                   2256:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2257:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2258:                                }
                   2259:                                /* printf("\n"); */
                   2260:                                /* fprintf(ficlog,"\n"); */
                   2261:                        }
1.243     brouard  2262:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2263:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2264:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2265:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2266:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2267:       /* decreased of more than 3.84  */
                   2268:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2269:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2270:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2271:                        
1.188     brouard  2272:       /* Starting the program with initial values given by a former maximization will simply change */
                   2273:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2274:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2275:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2276: #ifdef DEBUG
                   2277:       int k[2],l;
                   2278:       k[0]=1;
                   2279:       k[1]=-1;
                   2280:       printf("Max: %.12e",(*func)(p));
                   2281:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2282:       for (j=1;j<=n;j++) {
                   2283:        printf(" %.12e",p[j]);
                   2284:        fprintf(ficlog," %.12e",p[j]);
                   2285:       }
                   2286:       printf("\n");
                   2287:       fprintf(ficlog,"\n");
                   2288:       for(l=0;l<=1;l++) {
                   2289:        for (j=1;j<=n;j++) {
                   2290:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2291:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2292:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2293:        }
                   2294:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2295:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2296:       }
                   2297: #endif
                   2298: 
1.224     brouard  2299: #ifdef LINMINORIGINAL
                   2300: #else
                   2301:       free_ivector(flatdir,1,n); 
                   2302: #endif
1.126     brouard  2303:       free_vector(xit,1,n); 
                   2304:       free_vector(xits,1,n); 
                   2305:       free_vector(ptt,1,n); 
                   2306:       free_vector(pt,1,n); 
                   2307:       return; 
1.192     brouard  2308:     } /* enough precision */ 
1.240     brouard  2309:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2310:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2311:       ptt[j]=2.0*p[j]-pt[j]; 
                   2312:       xit[j]=p[j]-pt[j]; 
                   2313:       pt[j]=p[j]; 
                   2314:     } 
1.181     brouard  2315:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2316: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2317:                if (*iter <=4) {
1.225     brouard  2318: #else
                   2319: #endif
1.224     brouard  2320: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2321: #else
1.161     brouard  2322:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2323: #endif
1.162     brouard  2324:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2325:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2326:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2327:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2328:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2329:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2330:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2331:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2332:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2333:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2334:       /* mu² and del² are equal when f3=f1 */
                   2335:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2336:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2337:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2338:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2339: #ifdef NRCORIGINAL
                   2340:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2341: #else
                   2342:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2343:       t= t- del*SQR(fp-fptt);
1.183     brouard  2344: #endif
1.202     brouard  2345:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2346: #ifdef DEBUG
1.181     brouard  2347:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2348:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2349:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2350:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2351:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2352:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2353:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2354:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2355: #endif
1.183     brouard  2356: #ifdef POWELLORIGINAL
                   2357:       if (t < 0.0) { /* Then we use it for new direction */
                   2358: #else
1.182     brouard  2359:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2360:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2361:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2362:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2363:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2364:       } 
1.181     brouard  2365:       if (directest < 0.0) { /* Then we use it for new direction */
                   2366: #endif
1.191     brouard  2367: #ifdef DEBUGLINMIN
1.234     brouard  2368:        printf("Before linmin in direction P%d-P0\n",n);
                   2369:        for (j=1;j<=n;j++) {
                   2370:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2371:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2372:          if(j % ncovmodel == 0){
                   2373:            printf("\n");
                   2374:            fprintf(ficlog,"\n");
                   2375:          }
                   2376:        }
1.224     brouard  2377: #endif
                   2378: #ifdef LINMINORIGINAL
1.234     brouard  2379:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2380: #else
1.234     brouard  2381:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2382:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2383: #endif
1.234     brouard  2384:        
1.191     brouard  2385: #ifdef DEBUGLINMIN
1.234     brouard  2386:        for (j=1;j<=n;j++) { 
                   2387:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2388:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2389:          if(j % ncovmodel == 0){
                   2390:            printf("\n");
                   2391:            fprintf(ficlog,"\n");
                   2392:          }
                   2393:        }
1.224     brouard  2394: #endif
1.234     brouard  2395:        for (j=1;j<=n;j++) { 
                   2396:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2397:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2398:        }
1.224     brouard  2399: #ifdef LINMINORIGINAL
                   2400: #else
1.234     brouard  2401:        for (j=1, flatd=0;j<=n;j++) {
                   2402:          if(flatdir[j]>0)
                   2403:            flatd++;
                   2404:        }
                   2405:        if(flatd >0){
1.255     brouard  2406:          printf("%d flat directions: ",flatd);
                   2407:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2408:          for (j=1;j<=n;j++) { 
                   2409:            if(flatdir[j]>0){
                   2410:              printf("%d ",j);
                   2411:              fprintf(ficlog,"%d ",j);
                   2412:            }
                   2413:          }
                   2414:          printf("\n");
                   2415:          fprintf(ficlog,"\n");
                   2416:        }
1.191     brouard  2417: #endif
1.234     brouard  2418:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2419:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2420:        
1.126     brouard  2421: #ifdef DEBUG
1.234     brouard  2422:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2423:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2424:        for(j=1;j<=n;j++){
                   2425:          printf(" %lf",xit[j]);
                   2426:          fprintf(ficlog," %lf",xit[j]);
                   2427:        }
                   2428:        printf("\n");
                   2429:        fprintf(ficlog,"\n");
1.126     brouard  2430: #endif
1.192     brouard  2431:       } /* end of t or directest negative */
1.224     brouard  2432: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2433: #else
1.234     brouard  2434:       } /* end if (fptt < fp)  */
1.192     brouard  2435: #endif
1.225     brouard  2436: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2437:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2438: #else
1.224     brouard  2439: #endif
1.234     brouard  2440:                } /* loop iteration */ 
1.126     brouard  2441: } 
1.234     brouard  2442:   
1.126     brouard  2443: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2444:   
1.235     brouard  2445:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2446:   {
1.235     brouard  2447:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2448:        (and selected quantitative values in nres)
                   2449:        by left multiplying the unit
1.234     brouard  2450:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2451:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2452:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2453:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2454:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2455:   /* Initial matrix pimij */
                   2456:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2457:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2458:   /*  0,                   0                  , 1} */
                   2459:   /*
                   2460:    * and after some iteration: */
                   2461:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2462:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2463:   /*  0,                   0                  , 1} */
                   2464:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2465:   /* {0.51571254859325999, 0.4842874514067399, */
                   2466:   /*  0.51326036147820708, 0.48673963852179264} */
                   2467:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2468:     
1.126     brouard  2469:   int i, ii,j,k;
1.209     brouard  2470:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2471:   /* double **matprod2(); */ /* test */
1.218     brouard  2472:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2473:   double **newm;
1.209     brouard  2474:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2475:   int ncvloop=0;
1.169     brouard  2476:   
1.209     brouard  2477:   min=vector(1,nlstate);
                   2478:   max=vector(1,nlstate);
                   2479:   meandiff=vector(1,nlstate);
                   2480: 
1.218     brouard  2481:        /* Starting with matrix unity */
1.126     brouard  2482:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2483:     for (j=1;j<=nlstate+ndeath;j++){
                   2484:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2485:     }
1.169     brouard  2486:   
                   2487:   cov[1]=1.;
                   2488:   
                   2489:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2490:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2491:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2492:     ncvloop++;
1.126     brouard  2493:     newm=savm;
                   2494:     /* Covariates have to be included here again */
1.138     brouard  2495:     cov[2]=agefin;
1.187     brouard  2496:     if(nagesqr==1)
                   2497:       cov[3]= agefin*agefin;;
1.234     brouard  2498:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2499:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2500:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2501:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2502:     }
                   2503:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2504:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2505:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2506:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2507:     }
1.237     brouard  2508:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2509:       if(Dummy[Tvar[Tage[k]]]){
                   2510:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2511:       } else{
1.235     brouard  2512:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2513:       }
1.235     brouard  2514:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2515:     }
1.237     brouard  2516:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2517:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2518:       if(Dummy[Tvard[k][1]==0]){
                   2519:        if(Dummy[Tvard[k][2]==0]){
                   2520:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2521:        }else{
                   2522:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2523:        }
                   2524:       }else{
                   2525:        if(Dummy[Tvard[k][2]==0]){
                   2526:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2527:        }else{
                   2528:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2529:        }
                   2530:       }
1.234     brouard  2531:     }
1.138     brouard  2532:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2533:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2534:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2535:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2536:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2537:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2538:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2539:     
1.126     brouard  2540:     savm=oldm;
                   2541:     oldm=newm;
1.209     brouard  2542: 
                   2543:     for(j=1; j<=nlstate; j++){
                   2544:       max[j]=0.;
                   2545:       min[j]=1.;
                   2546:     }
                   2547:     for(i=1;i<=nlstate;i++){
                   2548:       sumnew=0;
                   2549:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2550:       for(j=1; j<=nlstate; j++){ 
                   2551:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2552:        max[j]=FMAX(max[j],prlim[i][j]);
                   2553:        min[j]=FMIN(min[j],prlim[i][j]);
                   2554:       }
                   2555:     }
                   2556: 
1.126     brouard  2557:     maxmax=0.;
1.209     brouard  2558:     for(j=1; j<=nlstate; j++){
                   2559:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2560:       maxmax=FMAX(maxmax,meandiff[j]);
                   2561:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2562:     } /* j loop */
1.203     brouard  2563:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2564:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2565:     if(maxmax < ftolpl){
1.209     brouard  2566:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2567:       free_vector(min,1,nlstate);
                   2568:       free_vector(max,1,nlstate);
                   2569:       free_vector(meandiff,1,nlstate);
1.126     brouard  2570:       return prlim;
                   2571:     }
1.169     brouard  2572:   } /* age loop */
1.208     brouard  2573:     /* After some age loop it doesn't converge */
1.209     brouard  2574:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2575: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2576:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2577:   free_vector(min,1,nlstate);
                   2578:   free_vector(max,1,nlstate);
                   2579:   free_vector(meandiff,1,nlstate);
1.208     brouard  2580:   
1.169     brouard  2581:   return prlim; /* should not reach here */
1.126     brouard  2582: }
                   2583: 
1.217     brouard  2584: 
                   2585:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2586: 
1.218     brouard  2587:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2588:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2589:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2590: {
1.218     brouard  2591:   /* Computes the prevalence limit in each live state at age x and covariate ij by left multiplying the unit
1.217     brouard  2592:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2593:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2594:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2595:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2596:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2597:   /* Initial matrix pimij */
                   2598:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2599:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2600:   /*  0,                   0                  , 1} */
                   2601:   /*
                   2602:    * and after some iteration: */
                   2603:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2604:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2605:   /*  0,                   0                  , 1} */
                   2606:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2607:   /* {0.51571254859325999, 0.4842874514067399, */
                   2608:   /*  0.51326036147820708, 0.48673963852179264} */
                   2609:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2610: 
                   2611:   int i, ii,j,k;
1.247     brouard  2612:   int first=0;
1.217     brouard  2613:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2614:   /* double **matprod2(); */ /* test */
                   2615:   double **out, cov[NCOVMAX+1], **bmij();
                   2616:   double **newm;
1.218     brouard  2617:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2618:   double        **oldm, **savm;  /* for use */
                   2619: 
1.217     brouard  2620:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2621:   int ncvloop=0;
                   2622:   
                   2623:   min=vector(1,nlstate);
                   2624:   max=vector(1,nlstate);
                   2625:   meandiff=vector(1,nlstate);
                   2626: 
1.218     brouard  2627:        dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2628:        oldm=oldms; savm=savms;
                   2629: 
                   2630:        /* Starting with matrix unity */
                   2631:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   2632:                for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2633:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2634:     }
                   2635:   
                   2636:   cov[1]=1.;
                   2637:   
                   2638:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2639:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2640:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2641:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2642:     ncvloop++;
1.218     brouard  2643:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2644:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2645:     /* Covariates have to be included here again */
                   2646:     cov[2]=agefin;
                   2647:     if(nagesqr==1)
                   2648:       cov[3]= agefin*agefin;;
1.242     brouard  2649:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2650:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2651:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   2652:       /* printf("bprevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   2653:     }
                   2654:     /* for (k=1; k<=cptcovn;k++) { */
                   2655:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2656:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2657:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2658:     /* } */
                   2659:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2660:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2661:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2662:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2663:     }
                   2664:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2665:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2666:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2667:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2668:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2669:       if(Dummy[Tvar[Tage[k]]]){
                   2670:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2671:       } else{
                   2672:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2673:       }
                   2674:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2675:     }
                   2676:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2677:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2678:       if(Dummy[Tvard[k][1]==0]){
                   2679:        if(Dummy[Tvard[k][2]==0]){
                   2680:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2681:        }else{
                   2682:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2683:        }
                   2684:       }else{
                   2685:        if(Dummy[Tvard[k][2]==0]){
                   2686:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2687:        }else{
                   2688:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2689:        }
                   2690:       }
1.217     brouard  2691:     }
                   2692:     
                   2693:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2694:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2695:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2696:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2697:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2698:                /* ij should be linked to the correct index of cov */
                   2699:                /* age and covariate values ij are in 'cov', but we need to pass
                   2700:                 * ij for the observed prevalence at age and status and covariate
                   2701:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2702:                 */
                   2703:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2704:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2705:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.217     brouard  2706:     savm=oldm;
                   2707:     oldm=newm;
                   2708:     for(j=1; j<=nlstate; j++){
                   2709:       max[j]=0.;
                   2710:       min[j]=1.;
                   2711:     }
                   2712:     for(j=1; j<=nlstate; j++){ 
                   2713:       for(i=1;i<=nlstate;i++){
1.234     brouard  2714:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2715:        bprlim[i][j]= newm[i][j];
                   2716:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2717:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2718:       }
                   2719:     }
1.218     brouard  2720:                
1.217     brouard  2721:     maxmax=0.;
                   2722:     for(i=1; i<=nlstate; i++){
                   2723:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2724:       maxmax=FMAX(maxmax,meandiff[i]);
                   2725:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
                   2726:     } /* j loop */
                   2727:     *ncvyear= -( (int)age- (int)agefin);
1.218     brouard  2728:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear);*/
1.217     brouard  2729:     if(maxmax < ftolpl){
1.220     brouard  2730:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2731:       free_vector(min,1,nlstate);
                   2732:       free_vector(max,1,nlstate);
                   2733:       free_vector(meandiff,1,nlstate);
                   2734:       return bprlim;
                   2735:     }
                   2736:   } /* age loop */
                   2737:     /* After some age loop it doesn't converge */
1.247     brouard  2738:   if(first){
                   2739:     first=1;
                   2740:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2741: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2742:   }
                   2743:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2744: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2745:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2746:   free_vector(min,1,nlstate);
                   2747:   free_vector(max,1,nlstate);
                   2748:   free_vector(meandiff,1,nlstate);
                   2749:   
                   2750:   return bprlim; /* should not reach here */
                   2751: }
                   2752: 
1.126     brouard  2753: /*************** transition probabilities ***************/ 
                   2754: 
                   2755: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2756: {
1.138     brouard  2757:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2758:      computes the probability to be observed in state j being in state i by appying the
                   2759:      model to the ncovmodel covariates (including constant and age).
                   2760:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2761:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2762:      ncth covariate in the global vector x is given by the formula:
                   2763:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2764:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2765:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2766:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2767:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2768:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2769:   */
                   2770:   double s1, lnpijopii;
1.126     brouard  2771:   /*double t34;*/
1.164     brouard  2772:   int i,j, nc, ii, jj;
1.126     brouard  2773: 
1.223     brouard  2774:   for(i=1; i<= nlstate; i++){
                   2775:     for(j=1; j<i;j++){
                   2776:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2777:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2778:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2779:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2780:       }
                   2781:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2782:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2783:     }
                   2784:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2785:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2786:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2787:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2788:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2789:       }
                   2790:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2791:     }
                   2792:   }
1.218     brouard  2793:   
1.223     brouard  2794:   for(i=1; i<= nlstate; i++){
                   2795:     s1=0;
                   2796:     for(j=1; j<i; j++){
                   2797:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2798:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2799:     }
                   2800:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2801:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2802:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2803:     }
                   2804:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2805:     ps[i][i]=1./(s1+1.);
                   2806:     /* Computing other pijs */
                   2807:     for(j=1; j<i; j++)
                   2808:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2809:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2810:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2811:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2812:   } /* end i */
1.218     brouard  2813:   
1.223     brouard  2814:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2815:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2816:       ps[ii][jj]=0;
                   2817:       ps[ii][ii]=1;
                   2818:     }
                   2819:   }
1.218     brouard  2820:   
                   2821:   
1.223     brouard  2822:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2823:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2824:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2825:   /*   } */
                   2826:   /*   printf("\n "); */
                   2827:   /* } */
                   2828:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2829:   /*
                   2830:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2831:                goto end;*/
1.223     brouard  2832:   return ps;
1.126     brouard  2833: }
                   2834: 
1.218     brouard  2835: /*************** backward transition probabilities ***************/ 
                   2836: 
                   2837:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2838: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2839:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2840: {
1.222     brouard  2841:   /* Computes the backward probability at age agefin and covariate ij
                   2842:    * and returns in **ps as well as **bmij.
                   2843:    */
1.218     brouard  2844:   int i, ii, j,k;
1.222     brouard  2845:   
                   2846:   double **out, **pmij();
                   2847:   double sumnew=0.;
1.218     brouard  2848:   double agefin;
1.222     brouard  2849:   
                   2850:   double **dnewm, **dsavm, **doldm;
                   2851:   double **bbmij;
                   2852:   
1.218     brouard  2853:   doldm=ddoldms; /* global pointers */
1.222     brouard  2854:   dnewm=ddnewms;
                   2855:   dsavm=ddsavms;
                   2856:   
                   2857:   agefin=cov[2];
                   2858:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
                   2859:      the observed prevalence (with this covariate ij) */
                   2860:   dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate);
                   2861:   /* We do have the matrix Px in savm  and we need pij */
                   2862:   for (j=1;j<=nlstate+ndeath;j++){
                   2863:     sumnew=0.; /* w1 p11 + w2 p21 only on live states */
                   2864:     for (ii=1;ii<=nlstate;ii++){
                   2865:       sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij];
                   2866:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
                   2867:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2868:       if(sumnew >= 1.e-10){
                   2869:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
                   2870:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2871:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
                   2872:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2873:        /* }else */
                   2874:        doldm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2875:       }else{
1.242     brouard  2876:        ;
                   2877:        /* printf("ii=%d, i=%d, doldm=%lf dsavm=%lf, probs=%lf, sumnew=%lf,agefin=%d\n",ii,j,doldm[ii][j],dsavm[ii][j],prevacurrent[(int)agefin][ii][ij],sumnew, (int)agefin); */
1.222     brouard  2878:       }
                   2879:     } /*End ii */
                   2880:   } /* End j, At the end doldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2881:   /* left Product of this diag matrix by dsavm=Px (newm=dsavm*doldm) */
                   2882:   bbmij=matprod2(dnewm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, doldm); /* Bug Valgrind */
                   2883:   /* dsavm=doldm; /\* dsavm is now diag [1/(w_1p1i+w_2 p2i)] but can be overwritten*\/ */
                   2884:   /* doldm=dnewm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2885:   /* dnewm=dsavm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2886:   /* left Product of this matrix by diag matrix of prevalences (savm) */
                   2887:   for (j=1;j<=nlstate+ndeath;j++){
                   2888:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2889:       dsavm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij] : 0.0);
                   2890:     }
                   2891:   } /* End j, At the end oldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2892:   ps=matprod2(doldm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dnewm); /* Bug Valgrind */
                   2893:   /* newm or out is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
                   2894:   /* end bmij */
                   2895:   return ps; 
1.218     brouard  2896: }
1.217     brouard  2897: /*************** transition probabilities ***************/ 
                   2898: 
1.218     brouard  2899: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2900: {
                   2901:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2902:      computes the probability to be observed in state j being in state i by appying the
                   2903:      model to the ncovmodel covariates (including constant and age).
                   2904:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2905:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2906:      ncth covariate in the global vector x is given by the formula:
                   2907:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2908:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2909:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2910:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2911:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2912:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2913:   */
                   2914:   double s1, lnpijopii;
                   2915:   /*double t34;*/
                   2916:   int i,j, nc, ii, jj;
                   2917: 
1.234     brouard  2918:   for(i=1; i<= nlstate; i++){
                   2919:     for(j=1; j<i;j++){
                   2920:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2921:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2922:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2923:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2924:       }
                   2925:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2926:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2927:     }
                   2928:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2929:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2930:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2931:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2932:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2933:       }
                   2934:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2935:     }
                   2936:   }
                   2937:   
                   2938:   for(i=1; i<= nlstate; i++){
                   2939:     s1=0;
                   2940:     for(j=1; j<i; j++){
                   2941:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2942:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2943:     }
                   2944:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2945:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2946:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2947:     }
                   2948:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2949:     ps[i][i]=1./(s1+1.);
                   2950:     /* Computing other pijs */
                   2951:     for(j=1; j<i; j++)
                   2952:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2953:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2954:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2955:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2956:   } /* end i */
                   2957:   
                   2958:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2959:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2960:       ps[ii][jj]=0;
                   2961:       ps[ii][ii]=1;
                   2962:     }
                   2963:   }
                   2964:   /* Added for backcast */ /* Transposed matrix too */
                   2965:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2966:     s1=0.;
                   2967:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   2968:       s1+=ps[ii][jj];
                   2969:     }
                   2970:     for(ii=1; ii<= nlstate; ii++){
                   2971:       ps[ii][jj]=ps[ii][jj]/s1;
                   2972:     }
                   2973:   }
                   2974:   /* Transposition */
                   2975:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2976:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   2977:       s1=ps[ii][jj];
                   2978:       ps[ii][jj]=ps[jj][ii];
                   2979:       ps[jj][ii]=s1;
                   2980:     }
                   2981:   }
                   2982:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2983:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2984:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2985:   /*   } */
                   2986:   /*   printf("\n "); */
                   2987:   /* } */
                   2988:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2989:   /*
                   2990:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   2991:     goto end;*/
                   2992:   return ps;
1.217     brouard  2993: }
                   2994: 
                   2995: 
1.126     brouard  2996: /**************** Product of 2 matrices ******************/
                   2997: 
1.145     brouard  2998: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  2999: {
                   3000:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3001:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3002:   /* in, b, out are matrice of pointers which should have been initialized 
                   3003:      before: only the contents of out is modified. The function returns
                   3004:      a pointer to pointers identical to out */
1.145     brouard  3005:   int i, j, k;
1.126     brouard  3006:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3007:     for(k=ncolol; k<=ncoloh; k++){
                   3008:       out[i][k]=0.;
                   3009:       for(j=ncl; j<=nch; j++)
                   3010:        out[i][k] +=in[i][j]*b[j][k];
                   3011:     }
1.126     brouard  3012:   return out;
                   3013: }
                   3014: 
                   3015: 
                   3016: /************* Higher Matrix Product ***************/
                   3017: 
1.235     brouard  3018: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3019: {
1.218     brouard  3020:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3021:      'nhstepm*hstepm*stepm' months (i.e. until
                   3022:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3023:      nhstepm*hstepm matrices. 
                   3024:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3025:      (typically every 2 years instead of every month which is too big 
                   3026:      for the memory).
                   3027:      Model is determined by parameters x and covariates have to be 
                   3028:      included manually here. 
                   3029: 
                   3030:      */
                   3031: 
                   3032:   int i, j, d, h, k;
1.131     brouard  3033:   double **out, cov[NCOVMAX+1];
1.126     brouard  3034:   double **newm;
1.187     brouard  3035:   double agexact;
1.214     brouard  3036:   double agebegin, ageend;
1.126     brouard  3037: 
                   3038:   /* Hstepm could be zero and should return the unit matrix */
                   3039:   for (i=1;i<=nlstate+ndeath;i++)
                   3040:     for (j=1;j<=nlstate+ndeath;j++){
                   3041:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3042:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3043:     }
                   3044:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3045:   for(h=1; h <=nhstepm; h++){
                   3046:     for(d=1; d <=hstepm; d++){
                   3047:       newm=savm;
                   3048:       /* Covariates have to be included here again */
                   3049:       cov[1]=1.;
1.214     brouard  3050:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3051:       cov[2]=agexact;
                   3052:       if(nagesqr==1)
1.227     brouard  3053:        cov[3]= agexact*agexact;
1.235     brouard  3054:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3055:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3056:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3057:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3058:       }
                   3059:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3060:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3061:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3062:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3063:       }
                   3064:       for (k=1; k<=cptcovage;k++){
                   3065:        if(Dummy[Tvar[Tage[k]]]){
                   3066:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3067:        } else{
                   3068:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3069:        }
                   3070:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3071:       }
                   3072:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3073:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3074:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3075:       }
                   3076:       /* for (k=1; k<=cptcovn;k++)  */
                   3077:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3078:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3079:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3080:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3081:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3082:       
                   3083:       
1.126     brouard  3084:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3085:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3086:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3087:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3088:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3089:       /* if((int)age == 70){ */
                   3090:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3091:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3092:       /*         printf("%d pmmij ",i); */
                   3093:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3094:       /*           printf("%f ",pmmij[i][j]); */
                   3095:       /*         } */
                   3096:       /*         printf(" oldm "); */
                   3097:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3098:       /*           printf("%f ",oldm[i][j]); */
                   3099:       /*         } */
                   3100:       /*         printf("\n"); */
                   3101:       /*       } */
                   3102:       /* } */
1.126     brouard  3103:       savm=oldm;
                   3104:       oldm=newm;
                   3105:     }
                   3106:     for(i=1; i<=nlstate+ndeath; i++)
                   3107:       for(j=1;j<=nlstate+ndeath;j++) {
1.218     brouard  3108:                                po[i][j][h]=newm[i][j];
                   3109:                                /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3110:       }
1.128     brouard  3111:     /*printf("h=%d ",h);*/
1.126     brouard  3112:   } /* end h */
1.218     brouard  3113:        /*     printf("\n H=%d \n",h); */
1.126     brouard  3114:   return po;
                   3115: }
                   3116: 
1.217     brouard  3117: /************* Higher Back Matrix Product ***************/
1.218     brouard  3118: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.222     brouard  3119: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij )
1.217     brouard  3120: {
1.218     brouard  3121:   /* Computes the transition matrix starting at age 'age' over
1.217     brouard  3122:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3123:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3124:      nhstepm*hstepm matrices.
                   3125:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3126:      (typically every 2 years instead of every month which is too big
1.217     brouard  3127:      for the memory).
1.218     brouard  3128:      Model is determined by parameters x and covariates have to be
                   3129:      included manually here.
1.217     brouard  3130: 
1.222     brouard  3131:   */
1.217     brouard  3132: 
                   3133:   int i, j, d, h, k;
                   3134:   double **out, cov[NCOVMAX+1];
                   3135:   double **newm;
                   3136:   double agexact;
                   3137:   double agebegin, ageend;
1.222     brouard  3138:   double **oldm, **savm;
1.217     brouard  3139: 
1.222     brouard  3140:   oldm=oldms;savm=savms;
1.217     brouard  3141:   /* Hstepm could be zero and should return the unit matrix */
                   3142:   for (i=1;i<=nlstate+ndeath;i++)
                   3143:     for (j=1;j<=nlstate+ndeath;j++){
                   3144:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3145:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3146:     }
                   3147:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3148:   for(h=1; h <=nhstepm; h++){
                   3149:     for(d=1; d <=hstepm; d++){
                   3150:       newm=savm;
                   3151:       /* Covariates have to be included here again */
                   3152:       cov[1]=1.;
                   3153:       agexact=age-((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
                   3154:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3155:       cov[2]=agexact;
                   3156:       if(nagesqr==1)
1.222     brouard  3157:        cov[3]= agexact*agexact;
1.218     brouard  3158:       for (k=1; k<=cptcovn;k++)
1.222     brouard  3159:        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   3160:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.217     brouard  3161:       for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
1.222     brouard  3162:        /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   3163:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3164:       /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
1.217     brouard  3165:       for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
1.222     brouard  3166:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3167:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
1.218     brouard  3168:                        
                   3169:                        
1.217     brouard  3170:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3171:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3172:       /* Careful transposed matrix */
1.222     brouard  3173:       /* age is in cov[2] */
1.218     brouard  3174:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3175:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3176:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3177:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3178:       /* if((int)age == 70){ */
                   3179:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3180:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3181:       /*         printf("%d pmmij ",i); */
                   3182:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3183:       /*           printf("%f ",pmmij[i][j]); */
                   3184:       /*         } */
                   3185:       /*         printf(" oldm "); */
                   3186:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3187:       /*           printf("%f ",oldm[i][j]); */
                   3188:       /*         } */
                   3189:       /*         printf("\n"); */
                   3190:       /*       } */
                   3191:       /* } */
                   3192:       savm=oldm;
                   3193:       oldm=newm;
                   3194:     }
                   3195:     for(i=1; i<=nlstate+ndeath; i++)
                   3196:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3197:        po[i][j][h]=newm[i][j];
                   3198:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.217     brouard  3199:       }
                   3200:     /*printf("h=%d ",h);*/
                   3201:   } /* end h */
1.222     brouard  3202:   /*     printf("\n H=%d \n",h); */
1.217     brouard  3203:   return po;
                   3204: }
                   3205: 
                   3206: 
1.162     brouard  3207: #ifdef NLOPT
                   3208:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3209:   double fret;
                   3210:   double *xt;
                   3211:   int j;
                   3212:   myfunc_data *d2 = (myfunc_data *) pd;
                   3213: /* xt = (p1-1); */
                   3214:   xt=vector(1,n); 
                   3215:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3216: 
                   3217:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3218:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3219:   printf("Function = %.12lf ",fret);
                   3220:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3221:   printf("\n");
                   3222:  free_vector(xt,1,n);
                   3223:   return fret;
                   3224: }
                   3225: #endif
1.126     brouard  3226: 
                   3227: /*************** log-likelihood *************/
                   3228: double func( double *x)
                   3229: {
1.226     brouard  3230:   int i, ii, j, k, mi, d, kk;
                   3231:   int ioffset=0;
                   3232:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3233:   double **out;
                   3234:   double lli; /* Individual log likelihood */
                   3235:   int s1, s2;
1.228     brouard  3236:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3237:   double bbh, survp;
                   3238:   long ipmx;
                   3239:   double agexact;
                   3240:   /*extern weight */
                   3241:   /* We are differentiating ll according to initial status */
                   3242:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3243:   /*for(i=1;i<imx;i++) 
                   3244:     printf(" %d\n",s[4][i]);
                   3245:   */
1.162     brouard  3246: 
1.226     brouard  3247:   ++countcallfunc;
1.162     brouard  3248: 
1.226     brouard  3249:   cov[1]=1.;
1.126     brouard  3250: 
1.226     brouard  3251:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3252:   ioffset=0;
1.226     brouard  3253:   if(mle==1){
                   3254:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3255:       /* Computes the values of the ncovmodel covariates of the model
                   3256:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3257:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3258:         to be observed in j being in i according to the model.
                   3259:       */
1.243     brouard  3260:       ioffset=2+nagesqr ;
1.233     brouard  3261:    /* Fixed */
1.234     brouard  3262:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3263:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3264:       }
1.226     brouard  3265:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3266:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3267:         has been calculated etc */
                   3268:       /* For an individual i, wav[i] gives the number of effective waves */
                   3269:       /* We compute the contribution to Likelihood of each effective transition
                   3270:         mw[mi][i] is real wave of the mi th effectve wave */
                   3271:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3272:         s2=s[mw[mi+1][i]][i];
                   3273:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3274:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3275:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3276:       */
                   3277:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3278:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3279:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3280:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3281:        }
                   3282:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3283:          for (j=1;j<=nlstate+ndeath;j++){
                   3284:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3285:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3286:          }
                   3287:        for(d=0; d<dh[mi][i]; d++){
                   3288:          newm=savm;
                   3289:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3290:          cov[2]=agexact;
                   3291:          if(nagesqr==1)
                   3292:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3293:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3294:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3295:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3296:          else
                   3297:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3298:          }
                   3299:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3300:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3301:          savm=oldm;
                   3302:          oldm=newm;
                   3303:        } /* end mult */
                   3304:        
                   3305:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3306:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3307:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3308:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3309:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3310:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3311:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3312:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3313:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3314:                                 * -stepm/2 to stepm/2 .
                   3315:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3316:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3317:                                 */
1.234     brouard  3318:        s1=s[mw[mi][i]][i];
                   3319:        s2=s[mw[mi+1][i]][i];
                   3320:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3321:        /* bias bh is positive if real duration
                   3322:         * is higher than the multiple of stepm and negative otherwise.
                   3323:         */
                   3324:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3325:        if( s2 > nlstate){ 
                   3326:          /* i.e. if s2 is a death state and if the date of death is known 
                   3327:             then the contribution to the likelihood is the probability to 
                   3328:             die between last step unit time and current  step unit time, 
                   3329:             which is also equal to probability to die before dh 
                   3330:             minus probability to die before dh-stepm . 
                   3331:             In version up to 0.92 likelihood was computed
                   3332:             as if date of death was unknown. Death was treated as any other
                   3333:             health state: the date of the interview describes the actual state
                   3334:             and not the date of a change in health state. The former idea was
                   3335:             to consider that at each interview the state was recorded
                   3336:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3337:             introduced the exact date of death then we should have modified
                   3338:             the contribution of an exact death to the likelihood. This new
                   3339:             contribution is smaller and very dependent of the step unit
                   3340:             stepm. It is no more the probability to die between last interview
                   3341:             and month of death but the probability to survive from last
                   3342:             interview up to one month before death multiplied by the
                   3343:             probability to die within a month. Thanks to Chris
                   3344:             Jackson for correcting this bug.  Former versions increased
                   3345:             mortality artificially. The bad side is that we add another loop
                   3346:             which slows down the processing. The difference can be up to 10%
                   3347:             lower mortality.
                   3348:          */
                   3349:          /* If, at the beginning of the maximization mostly, the
                   3350:             cumulative probability or probability to be dead is
                   3351:             constant (ie = 1) over time d, the difference is equal to
                   3352:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3353:             s1 at precedent wave, to be dead a month before current
                   3354:             wave is equal to probability, being at state s1 at
                   3355:             precedent wave, to be dead at mont of the current
                   3356:             wave. Then the observed probability (that this person died)
                   3357:             is null according to current estimated parameter. In fact,
                   3358:             it should be very low but not zero otherwise the log go to
                   3359:             infinity.
                   3360:          */
1.183     brouard  3361: /* #ifdef INFINITYORIGINAL */
                   3362: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3363: /* #else */
                   3364: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3365: /*         lli=log(mytinydouble); */
                   3366: /*       else */
                   3367: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3368: /* #endif */
1.226     brouard  3369:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3370:          
1.226     brouard  3371:        } else if  ( s2==-1 ) { /* alive */
                   3372:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3373:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3374:          /*survp += out[s1][j]; */
                   3375:          lli= log(survp);
                   3376:        }
                   3377:        else if  (s2==-4) { 
                   3378:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3379:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3380:          lli= log(survp); 
                   3381:        } 
                   3382:        else if  (s2==-5) { 
                   3383:          for (j=1,survp=0. ; j<=2; j++)  
                   3384:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3385:          lli= log(survp); 
                   3386:        } 
                   3387:        else{
                   3388:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3389:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3390:        } 
                   3391:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3392:        /*if(lli ==000.0)*/
                   3393:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3394:        ipmx +=1;
                   3395:        sw += weight[i];
                   3396:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3397:        /* if (lli < log(mytinydouble)){ */
                   3398:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3399:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3400:        /* } */
                   3401:       } /* end of wave */
                   3402:     } /* end of individual */
                   3403:   }  else if(mle==2){
                   3404:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3405:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3406:       for(mi=1; mi<= wav[i]-1; mi++){
                   3407:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3408:          for (j=1;j<=nlstate+ndeath;j++){
                   3409:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3410:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3411:          }
                   3412:        for(d=0; d<=dh[mi][i]; d++){
                   3413:          newm=savm;
                   3414:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3415:          cov[2]=agexact;
                   3416:          if(nagesqr==1)
                   3417:            cov[3]= agexact*agexact;
                   3418:          for (kk=1; kk<=cptcovage;kk++) {
                   3419:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3420:          }
                   3421:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3422:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3423:          savm=oldm;
                   3424:          oldm=newm;
                   3425:        } /* end mult */
                   3426:       
                   3427:        s1=s[mw[mi][i]][i];
                   3428:        s2=s[mw[mi+1][i]][i];
                   3429:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3430:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3431:        ipmx +=1;
                   3432:        sw += weight[i];
                   3433:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3434:       } /* end of wave */
                   3435:     } /* end of individual */
                   3436:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3437:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3438:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3439:       for(mi=1; mi<= wav[i]-1; mi++){
                   3440:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3441:          for (j=1;j<=nlstate+ndeath;j++){
                   3442:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3443:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3444:          }
                   3445:        for(d=0; d<dh[mi][i]; d++){
                   3446:          newm=savm;
                   3447:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3448:          cov[2]=agexact;
                   3449:          if(nagesqr==1)
                   3450:            cov[3]= agexact*agexact;
                   3451:          for (kk=1; kk<=cptcovage;kk++) {
                   3452:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3453:          }
                   3454:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3455:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3456:          savm=oldm;
                   3457:          oldm=newm;
                   3458:        } /* end mult */
                   3459:       
                   3460:        s1=s[mw[mi][i]][i];
                   3461:        s2=s[mw[mi+1][i]][i];
                   3462:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3463:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3464:        ipmx +=1;
                   3465:        sw += weight[i];
                   3466:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3467:       } /* end of wave */
                   3468:     } /* end of individual */
                   3469:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3470:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3471:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3472:       for(mi=1; mi<= wav[i]-1; mi++){
                   3473:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3474:          for (j=1;j<=nlstate+ndeath;j++){
                   3475:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3476:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3477:          }
                   3478:        for(d=0; d<dh[mi][i]; d++){
                   3479:          newm=savm;
                   3480:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3481:          cov[2]=agexact;
                   3482:          if(nagesqr==1)
                   3483:            cov[3]= agexact*agexact;
                   3484:          for (kk=1; kk<=cptcovage;kk++) {
                   3485:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3486:          }
1.126     brouard  3487:        
1.226     brouard  3488:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3489:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3490:          savm=oldm;
                   3491:          oldm=newm;
                   3492:        } /* end mult */
                   3493:       
                   3494:        s1=s[mw[mi][i]][i];
                   3495:        s2=s[mw[mi+1][i]][i];
                   3496:        if( s2 > nlstate){ 
                   3497:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3498:        } else if  ( s2==-1 ) { /* alive */
                   3499:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3500:            survp += out[s1][j];
                   3501:          lli= log(survp);
                   3502:        }else{
                   3503:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3504:        }
                   3505:        ipmx +=1;
                   3506:        sw += weight[i];
                   3507:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3508: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3509:       } /* end of wave */
                   3510:     } /* end of individual */
                   3511:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3512:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3513:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3514:       for(mi=1; mi<= wav[i]-1; mi++){
                   3515:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3516:          for (j=1;j<=nlstate+ndeath;j++){
                   3517:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3518:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3519:          }
                   3520:        for(d=0; d<dh[mi][i]; d++){
                   3521:          newm=savm;
                   3522:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3523:          cov[2]=agexact;
                   3524:          if(nagesqr==1)
                   3525:            cov[3]= agexact*agexact;
                   3526:          for (kk=1; kk<=cptcovage;kk++) {
                   3527:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3528:          }
1.126     brouard  3529:        
1.226     brouard  3530:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3531:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3532:          savm=oldm;
                   3533:          oldm=newm;
                   3534:        } /* end mult */
                   3535:       
                   3536:        s1=s[mw[mi][i]][i];
                   3537:        s2=s[mw[mi+1][i]][i];
                   3538:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3539:        ipmx +=1;
                   3540:        sw += weight[i];
                   3541:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3542:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3543:       } /* end of wave */
                   3544:     } /* end of individual */
                   3545:   } /* End of if */
                   3546:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3547:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3548:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3549:   return -l;
1.126     brouard  3550: }
                   3551: 
                   3552: /*************** log-likelihood *************/
                   3553: double funcone( double *x)
                   3554: {
1.228     brouard  3555:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3556:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3557:   int ioffset=0;
1.131     brouard  3558:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3559:   double **out;
                   3560:   double lli; /* Individual log likelihood */
                   3561:   double llt;
                   3562:   int s1, s2;
1.228     brouard  3563:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3564: 
1.126     brouard  3565:   double bbh, survp;
1.187     brouard  3566:   double agexact;
1.214     brouard  3567:   double agebegin, ageend;
1.126     brouard  3568:   /*extern weight */
                   3569:   /* We are differentiating ll according to initial status */
                   3570:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3571:   /*for(i=1;i<imx;i++) 
                   3572:     printf(" %d\n",s[4][i]);
                   3573:   */
                   3574:   cov[1]=1.;
                   3575: 
                   3576:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3577:   ioffset=0;
                   3578:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3579:     /* ioffset=2+nagesqr+cptcovage; */
                   3580:     ioffset=2+nagesqr;
1.232     brouard  3581:     /* Fixed */
1.224     brouard  3582:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3583:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3584:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3585:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3586: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3587: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3588: /*    cov[2+6]=covar[2][i]; V2  */
                   3589: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3590: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3591: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3592: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3593: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3594: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3595:     }
1.232     brouard  3596:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3597:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3598:     /* } */
1.231     brouard  3599:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3600:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3601:     /* } */
1.225     brouard  3602:     
1.233     brouard  3603: 
                   3604:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3605:     /* Wave varying (but not age varying) */
                   3606:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3607:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3608:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3609:       }
1.232     brouard  3610:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3611:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3612:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3613:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3614:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3615:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3616:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3617:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3618:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3619:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3620:       /* } */
1.126     brouard  3621:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3622:        for (j=1;j<=nlstate+ndeath;j++){
                   3623:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3624:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3625:        }
1.214     brouard  3626:       
                   3627:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3628:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3629:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3630:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3631:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3632:          and mw[mi+1][i]. dh depends on stepm.*/
                   3633:        newm=savm;
1.247     brouard  3634:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3635:        cov[2]=agexact;
                   3636:        if(nagesqr==1)
                   3637:          cov[3]= agexact*agexact;
                   3638:        for (kk=1; kk<=cptcovage;kk++) {
                   3639:          if(!FixedV[Tvar[Tage[kk]]])
                   3640:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3641:          else
                   3642:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3643:        }
                   3644:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3645:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3646:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3647:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3648:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3649:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3650:        savm=oldm;
                   3651:        oldm=newm;
1.126     brouard  3652:       } /* end mult */
                   3653:       
                   3654:       s1=s[mw[mi][i]][i];
                   3655:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3656:       /* if(s2==-1){ */
                   3657:       /*       printf(" s1=%d, s2=%d i=%d \n", s1, s2, i); */
                   3658:       /*       /\* exit(1); *\/ */
                   3659:       /* } */
1.126     brouard  3660:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3661:       /* bias is positive if real duration
                   3662:        * is higher than the multiple of stepm and negative otherwise.
                   3663:        */
                   3664:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3665:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3666:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3667:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3668:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3669:        lli= log(survp);
1.126     brouard  3670:       }else if (mle==1){
1.242     brouard  3671:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3672:       } else if(mle==2){
1.242     brouard  3673:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3674:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3675:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3676:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3677:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3678:       } else{  /* mle=0 back to 1 */
1.242     brouard  3679:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3680:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3681:       } /* End of if */
                   3682:       ipmx +=1;
                   3683:       sw += weight[i];
                   3684:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3685:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3686:       if(globpr){
1.246     brouard  3687:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3688:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3689:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
                   3690:                2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
                   3691:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3692:          llt +=ll[k]*gipmx/gsw;
                   3693:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3694:        }
                   3695:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3696:       }
1.232     brouard  3697:        } /* end of wave */
                   3698: } /* end of individual */
                   3699: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3700: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3701: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3702: if(globpr==0){ /* First time we count the contributions and weights */
                   3703:        gipmx=ipmx;
                   3704:        gsw=sw;
                   3705: }
                   3706: return -l;
1.126     brouard  3707: }
                   3708: 
                   3709: 
                   3710: /*************** function likelione ***********/
                   3711: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3712: {
                   3713:   /* This routine should help understanding what is done with 
                   3714:      the selection of individuals/waves and
                   3715:      to check the exact contribution to the likelihood.
                   3716:      Plotting could be done.
                   3717:    */
                   3718:   int k;
                   3719: 
                   3720:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3721:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3722:     strcat(fileresilk,fileresu);
1.126     brouard  3723:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3724:       printf("Problem with resultfile: %s\n", fileresilk);
                   3725:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3726:     }
1.214     brouard  3727:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3728:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3729:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3730:     for(k=1; k<=nlstate; k++) 
                   3731:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3732:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3733:   }
                   3734: 
                   3735:   *fretone=(*funcone)(p);
                   3736:   if(*globpri !=0){
                   3737:     fclose(ficresilk);
1.205     brouard  3738:     if (mle ==0)
                   3739:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3740:     else if(mle >=1)
                   3741:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3742:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3743:     
1.208     brouard  3744:       
                   3745:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3746:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3747: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3748:     }
1.207     brouard  3749:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3750: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3751:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3752: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3753:     fflush(fichtm);
1.205     brouard  3754:   }
1.126     brouard  3755:   return;
                   3756: }
                   3757: 
                   3758: 
                   3759: /*********** Maximum Likelihood Estimation ***************/
                   3760: 
                   3761: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3762: {
1.165     brouard  3763:   int i,j, iter=0;
1.126     brouard  3764:   double **xi;
                   3765:   double fret;
                   3766:   double fretone; /* Only one call to likelihood */
                   3767:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3768: 
                   3769: #ifdef NLOPT
                   3770:   int creturn;
                   3771:   nlopt_opt opt;
                   3772:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3773:   double *lb;
                   3774:   double minf; /* the minimum objective value, upon return */
                   3775:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3776:   myfunc_data dinst, *d = &dinst;
                   3777: #endif
                   3778: 
                   3779: 
1.126     brouard  3780:   xi=matrix(1,npar,1,npar);
                   3781:   for (i=1;i<=npar;i++)
                   3782:     for (j=1;j<=npar;j++)
                   3783:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3784:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3785:   strcpy(filerespow,"POW_"); 
1.126     brouard  3786:   strcat(filerespow,fileres);
                   3787:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3788:     printf("Problem with resultfile: %s\n", filerespow);
                   3789:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3790:   }
                   3791:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3792:   for (i=1;i<=nlstate;i++)
                   3793:     for(j=1;j<=nlstate+ndeath;j++)
                   3794:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3795:   fprintf(ficrespow,"\n");
1.162     brouard  3796: #ifdef POWELL
1.126     brouard  3797:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3798: #endif
1.126     brouard  3799: 
1.162     brouard  3800: #ifdef NLOPT
                   3801: #ifdef NEWUOA
                   3802:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3803: #else
                   3804:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3805: #endif
                   3806:   lb=vector(0,npar-1);
                   3807:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3808:   nlopt_set_lower_bounds(opt, lb);
                   3809:   nlopt_set_initial_step1(opt, 0.1);
                   3810:   
                   3811:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3812:   d->function = func;
                   3813:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3814:   nlopt_set_min_objective(opt, myfunc, d);
                   3815:   nlopt_set_xtol_rel(opt, ftol);
                   3816:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3817:     printf("nlopt failed! %d\n",creturn); 
                   3818:   }
                   3819:   else {
                   3820:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3821:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3822:     iter=1; /* not equal */
                   3823:   }
                   3824:   nlopt_destroy(opt);
                   3825: #endif
1.126     brouard  3826:   free_matrix(xi,1,npar,1,npar);
                   3827:   fclose(ficrespow);
1.203     brouard  3828:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3829:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3830:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3831: 
                   3832: }
                   3833: 
                   3834: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3835: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3836: {
                   3837:   double  **a,**y,*x,pd;
1.203     brouard  3838:   /* double **hess; */
1.164     brouard  3839:   int i, j;
1.126     brouard  3840:   int *indx;
                   3841: 
                   3842:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3843:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3844:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3845:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3846:   double gompertz(double p[]);
1.203     brouard  3847:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3848: 
                   3849:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3850:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3851:   for (i=1;i<=npar;i++){
1.203     brouard  3852:     printf("%d-",i);fflush(stdout);
                   3853:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3854:    
                   3855:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3856:     
                   3857:     /*  printf(" %f ",p[i]);
                   3858:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3859:   }
                   3860:   
                   3861:   for (i=1;i<=npar;i++) {
                   3862:     for (j=1;j<=npar;j++)  {
                   3863:       if (j>i) { 
1.203     brouard  3864:        printf(".%d-%d",i,j);fflush(stdout);
                   3865:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3866:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3867:        
                   3868:        hess[j][i]=hess[i][j];    
                   3869:        /*printf(" %lf ",hess[i][j]);*/
                   3870:       }
                   3871:     }
                   3872:   }
                   3873:   printf("\n");
                   3874:   fprintf(ficlog,"\n");
                   3875: 
                   3876:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3877:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3878:   
                   3879:   a=matrix(1,npar,1,npar);
                   3880:   y=matrix(1,npar,1,npar);
                   3881:   x=vector(1,npar);
                   3882:   indx=ivector(1,npar);
                   3883:   for (i=1;i<=npar;i++)
                   3884:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3885:   ludcmp(a,npar,indx,&pd);
                   3886: 
                   3887:   for (j=1;j<=npar;j++) {
                   3888:     for (i=1;i<=npar;i++) x[i]=0;
                   3889:     x[j]=1;
                   3890:     lubksb(a,npar,indx,x);
                   3891:     for (i=1;i<=npar;i++){ 
                   3892:       matcov[i][j]=x[i];
                   3893:     }
                   3894:   }
                   3895: 
                   3896:   printf("\n#Hessian matrix#\n");
                   3897:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   3898:   for (i=1;i<=npar;i++) { 
                   3899:     for (j=1;j<=npar;j++) { 
1.203     brouard  3900:       printf("%.6e ",hess[i][j]);
                   3901:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  3902:     }
                   3903:     printf("\n");
                   3904:     fprintf(ficlog,"\n");
                   3905:   }
                   3906: 
1.203     brouard  3907:   /* printf("\n#Covariance matrix#\n"); */
                   3908:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   3909:   /* for (i=1;i<=npar;i++) {  */
                   3910:   /*   for (j=1;j<=npar;j++) {  */
                   3911:   /*     printf("%.6e ",matcov[i][j]); */
                   3912:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   3913:   /*   } */
                   3914:   /*   printf("\n"); */
                   3915:   /*   fprintf(ficlog,"\n"); */
                   3916:   /* } */
                   3917: 
1.126     brouard  3918:   /* Recompute Inverse */
1.203     brouard  3919:   /* for (i=1;i<=npar;i++) */
                   3920:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   3921:   /* ludcmp(a,npar,indx,&pd); */
                   3922: 
                   3923:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   3924: 
                   3925:   /* for (j=1;j<=npar;j++) { */
                   3926:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   3927:   /*   x[j]=1; */
                   3928:   /*   lubksb(a,npar,indx,x); */
                   3929:   /*   for (i=1;i<=npar;i++){  */
                   3930:   /*     y[i][j]=x[i]; */
                   3931:   /*     printf("%.3e ",y[i][j]); */
                   3932:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   3933:   /*   } */
                   3934:   /*   printf("\n"); */
                   3935:   /*   fprintf(ficlog,"\n"); */
                   3936:   /* } */
                   3937: 
                   3938:   /* Verifying the inverse matrix */
                   3939: #ifdef DEBUGHESS
                   3940:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  3941: 
1.203     brouard  3942:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   3943:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  3944: 
                   3945:   for (j=1;j<=npar;j++) {
                   3946:     for (i=1;i<=npar;i++){ 
1.203     brouard  3947:       printf("%.2f ",y[i][j]);
                   3948:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  3949:     }
                   3950:     printf("\n");
                   3951:     fprintf(ficlog,"\n");
                   3952:   }
1.203     brouard  3953: #endif
1.126     brouard  3954: 
                   3955:   free_matrix(a,1,npar,1,npar);
                   3956:   free_matrix(y,1,npar,1,npar);
                   3957:   free_vector(x,1,npar);
                   3958:   free_ivector(indx,1,npar);
1.203     brouard  3959:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  3960: 
                   3961: 
                   3962: }
                   3963: 
                   3964: /*************** hessian matrix ****************/
                   3965: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  3966: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  3967:   int i;
                   3968:   int l=1, lmax=20;
1.203     brouard  3969:   double k1,k2, res, fx;
1.132     brouard  3970:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  3971:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   3972:   int k=0,kmax=10;
                   3973:   double l1;
                   3974: 
                   3975:   fx=func(x);
                   3976:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  3977:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  3978:     l1=pow(10,l);
                   3979:     delts=delt;
                   3980:     for(k=1 ; k <kmax; k=k+1){
                   3981:       delt = delta*(l1*k);
                   3982:       p2[theta]=x[theta] +delt;
1.145     brouard  3983:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  3984:       p2[theta]=x[theta]-delt;
                   3985:       k2=func(p2)-fx;
                   3986:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  3987:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  3988:       
1.203     brouard  3989: #ifdef DEBUGHESSII
1.126     brouard  3990:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3991:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3992: #endif
                   3993:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   3994:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   3995:        k=kmax;
                   3996:       }
                   3997:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  3998:        k=kmax; l=lmax*10;
1.126     brouard  3999:       }
                   4000:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4001:        delts=delt;
                   4002:       }
1.203     brouard  4003:     } /* End loop k */
1.126     brouard  4004:   }
                   4005:   delti[theta]=delts;
                   4006:   return res; 
                   4007:   
                   4008: }
                   4009: 
1.203     brouard  4010: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4011: {
                   4012:   int i;
1.164     brouard  4013:   int l=1, lmax=20;
1.126     brouard  4014:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4015:   double p2[MAXPARM+1];
1.203     brouard  4016:   int k, kmax=1;
                   4017:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4018: 
                   4019:   int firstime=0;
1.203     brouard  4020:   
1.126     brouard  4021:   fx=func(x);
1.203     brouard  4022:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4023:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4024:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4025:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4026:     k1=func(p2)-fx;
                   4027:   
1.203     brouard  4028:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4029:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4030:     k2=func(p2)-fx;
                   4031:   
1.203     brouard  4032:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4033:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4034:     k3=func(p2)-fx;
                   4035:   
1.203     brouard  4036:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4037:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4038:     k4=func(p2)-fx;
1.203     brouard  4039:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4040:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4041:       firstime=1;
1.203     brouard  4042:       kmax=kmax+10;
1.208     brouard  4043:     }
                   4044:     if(kmax >=10 || firstime ==1){
1.246     brouard  4045:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4046:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4047:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4048:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4049:     }
                   4050: #ifdef DEBUGHESSIJ
                   4051:     v1=hess[thetai][thetai];
                   4052:     v2=hess[thetaj][thetaj];
                   4053:     cv12=res;
                   4054:     /* Computing eigen value of Hessian matrix */
                   4055:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4056:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4057:     if ((lc2 <0) || (lc1 <0) ){
                   4058:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4059:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4060:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4061:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4062:     }
1.126     brouard  4063: #endif
                   4064:   }
                   4065:   return res;
                   4066: }
                   4067: 
1.203     brouard  4068:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4069: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4070: /* { */
                   4071: /*   int i; */
                   4072: /*   int l=1, lmax=20; */
                   4073: /*   double k1,k2,k3,k4,res,fx; */
                   4074: /*   double p2[MAXPARM+1]; */
                   4075: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4076: /*   int k=0,kmax=10; */
                   4077: /*   double l1; */
                   4078:   
                   4079: /*   fx=func(x); */
                   4080: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4081: /*     l1=pow(10,l); */
                   4082: /*     delts=delt; */
                   4083: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4084: /*       delt = delti*(l1*k); */
                   4085: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4086: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4087: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4088: /*       k1=func(p2)-fx; */
                   4089:       
                   4090: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4091: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4092: /*       k2=func(p2)-fx; */
                   4093:       
                   4094: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4095: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4096: /*       k3=func(p2)-fx; */
                   4097:       
                   4098: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4099: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4100: /*       k4=func(p2)-fx; */
                   4101: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4102: /* #ifdef DEBUGHESSIJ */
                   4103: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4104: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4105: /* #endif */
                   4106: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4107: /*     k=kmax; */
                   4108: /*       } */
                   4109: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4110: /*     k=kmax; l=lmax*10; */
                   4111: /*       } */
                   4112: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4113: /*     delts=delt; */
                   4114: /*       } */
                   4115: /*     } /\* End loop k *\/ */
                   4116: /*   } */
                   4117: /*   delti[theta]=delts; */
                   4118: /*   return res;  */
                   4119: /* } */
                   4120: 
                   4121: 
1.126     brouard  4122: /************** Inverse of matrix **************/
                   4123: void ludcmp(double **a, int n, int *indx, double *d) 
                   4124: { 
                   4125:   int i,imax,j,k; 
                   4126:   double big,dum,sum,temp; 
                   4127:   double *vv; 
                   4128:  
                   4129:   vv=vector(1,n); 
                   4130:   *d=1.0; 
                   4131:   for (i=1;i<=n;i++) { 
                   4132:     big=0.0; 
                   4133:     for (j=1;j<=n;j++) 
                   4134:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256   ! brouard  4135:     if (big == 0.0){
        !          4136:       printf(" Singular Hessian matrix at row %d:\n",i);
        !          4137:       for (j=1;j<=n;j++) {
        !          4138:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
        !          4139:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
        !          4140:       }
        !          4141:       fflush(ficlog);
        !          4142:       fclose(ficlog);
        !          4143:       nrerror("Singular matrix in routine ludcmp"); 
        !          4144:     }
1.126     brouard  4145:     vv[i]=1.0/big; 
                   4146:   } 
                   4147:   for (j=1;j<=n;j++) { 
                   4148:     for (i=1;i<j;i++) { 
                   4149:       sum=a[i][j]; 
                   4150:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4151:       a[i][j]=sum; 
                   4152:     } 
                   4153:     big=0.0; 
                   4154:     for (i=j;i<=n;i++) { 
                   4155:       sum=a[i][j]; 
                   4156:       for (k=1;k<j;k++) 
                   4157:        sum -= a[i][k]*a[k][j]; 
                   4158:       a[i][j]=sum; 
                   4159:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4160:        big=dum; 
                   4161:        imax=i; 
                   4162:       } 
                   4163:     } 
                   4164:     if (j != imax) { 
                   4165:       for (k=1;k<=n;k++) { 
                   4166:        dum=a[imax][k]; 
                   4167:        a[imax][k]=a[j][k]; 
                   4168:        a[j][k]=dum; 
                   4169:       } 
                   4170:       *d = -(*d); 
                   4171:       vv[imax]=vv[j]; 
                   4172:     } 
                   4173:     indx[j]=imax; 
                   4174:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4175:     if (j != n) { 
                   4176:       dum=1.0/(a[j][j]); 
                   4177:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4178:     } 
                   4179:   } 
                   4180:   free_vector(vv,1,n);  /* Doesn't work */
                   4181: ;
                   4182: } 
                   4183: 
                   4184: void lubksb(double **a, int n, int *indx, double b[]) 
                   4185: { 
                   4186:   int i,ii=0,ip,j; 
                   4187:   double sum; 
                   4188:  
                   4189:   for (i=1;i<=n;i++) { 
                   4190:     ip=indx[i]; 
                   4191:     sum=b[ip]; 
                   4192:     b[ip]=b[i]; 
                   4193:     if (ii) 
                   4194:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4195:     else if (sum) ii=i; 
                   4196:     b[i]=sum; 
                   4197:   } 
                   4198:   for (i=n;i>=1;i--) { 
                   4199:     sum=b[i]; 
                   4200:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4201:     b[i]=sum/a[i][i]; 
                   4202:   } 
                   4203: } 
                   4204: 
                   4205: void pstamp(FILE *fichier)
                   4206: {
1.196     brouard  4207:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4208: }
                   4209: 
1.253     brouard  4210: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4211: 
                   4212:   /* y=a+bx regression */
                   4213:   double   sumx = 0.0;                        /* sum of x                      */
                   4214:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4215:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4216:   double   sumy = 0.0;                        /* sum of y                      */
                   4217:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4218:   double   sume2; /* sum of square or residuals */
                   4219:   double yhat;
                   4220:   
                   4221:   double denom=0;
                   4222:   int i;
                   4223:   int ne=*no;
                   4224:   
                   4225:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4226:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4227:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4228:       continue;
                   4229:     }
                   4230:     ne=ne+1;
                   4231:     sumx  += x[i];       
                   4232:     sumx2 += x[i]*x[i];  
                   4233:     sumxy += x[i] * y[i];
                   4234:     sumy  += y[i];      
                   4235:     sumy2 += y[i]*y[i]; 
                   4236:     denom = (ne * sumx2 - sumx*sumx);
                   4237:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4238:   } 
                   4239:   
                   4240:   denom = (ne * sumx2 - sumx*sumx);
                   4241:   if (denom == 0) {
                   4242:     // vertical, slope m is infinity
                   4243:     *b = INFINITY;
                   4244:     *a = 0;
                   4245:     if (r) *r = 0;
                   4246:     return 1;
                   4247:   }
                   4248:   
                   4249:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   4250:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   4251:   if (r!=NULL) {
                   4252:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   4253:       sqrt((sumx2 - sumx*sumx/ne) *
                   4254:           (sumy2 - sumy*sumy/ne));
                   4255:   }
                   4256:   *no=ne;
                   4257:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4258:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4259:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4260:       continue;
                   4261:     }
                   4262:     ne=ne+1;
                   4263:     yhat = y[i] - *a -*b* x[i];
                   4264:     sume2  += yhat * yhat ;       
                   4265:     
                   4266:     denom = (ne * sumx2 - sumx*sumx);
                   4267:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4268:   } 
                   4269:   *sb = sqrt(sume2/(ne-2)/(sumx2 - sumx * sumx /ne));
                   4270:   *sa= *sb * sqrt(sumx2/ne);
                   4271:   
                   4272:   return 0; 
                   4273: }
                   4274: 
1.126     brouard  4275: /************ Frequencies ********************/
1.251     brouard  4276: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4277:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4278:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4279: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4280:   
1.253     brouard  4281:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0;
1.226     brouard  4282:   int iind=0, iage=0;
                   4283:   int mi; /* Effective wave */
                   4284:   int first;
                   4285:   double ***freq; /* Frequencies */
1.253     brouard  4286:   double *x, *y, a,b,r, sa, sb; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4287:   int no;
1.226     brouard  4288:   double *meanq;
                   4289:   double **meanqt;
                   4290:   double *pp, **prop, *posprop, *pospropt;
                   4291:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4292:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4293:   double agebegin, ageend;
                   4294:     
                   4295:   pp=vector(1,nlstate);
1.251     brouard  4296:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4297:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4298:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4299:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4300:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4301:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4302:   strcpy(fileresp,"P_");
                   4303:   strcat(fileresp,fileresu);
                   4304:   /*strcat(fileresphtm,fileresu);*/
                   4305:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4306:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4307:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4308:     exit(0);
                   4309:   }
1.240     brouard  4310:   
1.226     brouard  4311:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4312:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4313:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4314:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4315:     fflush(ficlog);
                   4316:     exit(70); 
                   4317:   }
                   4318:   else{
                   4319:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4320: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4321: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4322:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4323:   }
1.237     brouard  4324:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4325:   
1.226     brouard  4326:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4327:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4328:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4329:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4330:     fflush(ficlog);
                   4331:     exit(70); 
1.240     brouard  4332:   } else{
1.226     brouard  4333:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4334: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4335: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4336:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4337:   }
1.240     brouard  4338:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4339:   
1.253     brouard  4340:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4341:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4342:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4343:   j1=0;
1.126     brouard  4344:   
1.227     brouard  4345:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4346:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4347:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4348:   
                   4349:   
1.226     brouard  4350:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4351:      reference=low_education V1=0,V2=0
                   4352:      med_educ                V1=1 V2=0, 
                   4353:      high_educ               V1=0 V2=1
                   4354:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4355:   */
1.249     brouard  4356:   dateintsum=0;
                   4357:   k2cpt=0;
                   4358: 
1.253     brouard  4359:   if(cptcoveff == 0 )
                   4360:     nl=1;  /* Constant model only */
                   4361:   else
                   4362:     nl=2;
                   4363:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4364:     if(nj==1)
                   4365:       j=0;  /* First pass for the constant */
                   4366:     else
                   4367:       j=cptcoveff; /* Other passes for the covariate values */
1.251     brouard  4368:     first=1;
                   4369:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on covariates combination in order of model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
                   4370:       posproptt=0.;
                   4371:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4372:        scanf("%d", i);*/
                   4373:       for (i=-5; i<=nlstate+ndeath; i++)  
                   4374:        for (jk=-5; jk<=nlstate+ndeath; jk++)  
                   4375:          for(m=iagemin; m <= iagemax+3; m++)
                   4376:            freq[i][jk][m]=0;
                   4377:       
                   4378:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4379:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4380:          prop[i][m]=0;
                   4381:        posprop[i]=0;
                   4382:        pospropt[i]=0;
                   4383:       }
                   4384:       /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4385:       /*   meanq[z1]+=0.; */
                   4386:       /*   for(m=1;m<=lastpass;m++){ */
                   4387:       /*       meanqt[m][z1]=0.; */
                   4388:       /*   } */
                   4389:       /* } */
                   4390:       
                   4391:       /* dateintsum=0; */
                   4392:       /* k2cpt=0; */
                   4393:       
                   4394:       /* For that combination of covariate j1, we count and print the frequencies in one pass */
                   4395:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4396:        bool=1;
                   4397:        if(j !=0){
                   4398:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4399:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4400:              /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4401:              /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4402:              /* } */
                   4403:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4404:                /* if(Tvaraff[z1] ==-20){ */
                   4405:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4406:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4407:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4408:                /* }else  */
                   4409:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
                   4410:                  /* Tests if this individual iind responded to combination j1 (V4=1 V3=0) */
                   4411:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4412:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4413:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4414:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4415:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4416:                } /* Onlyf fixed */
                   4417:              } /* end z1 */
                   4418:            } /* cptcovn > 0 */
                   4419:          } /* end any */
                   4420:        }/* end j==0 */
                   4421:        if (bool==1){ /* We selected an individual iind satisfying combination j1 or all fixed */
                   4422:          /* for(m=firstpass; m<=lastpass; m++){ */
                   4423:          for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4424:            m=mw[mi][iind];
                   4425:            if(j!=0){
                   4426:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4427:                for (z1=1; z1<=cptcoveff; z1++) {
                   4428:                  if( Fixed[Tmodelind[z1]]==1){
                   4429:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4430:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4431:                                                                                      value is -1, we don't select. It differs from the 
                   4432:                                                                                      constant and age model which counts them. */
                   4433:                      bool=0; /* not selected */
                   4434:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4435:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4436:                      bool=0;
                   4437:                    }
                   4438:                  }
                   4439:                }
                   4440:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4441:            } /* end j==0 */
                   4442:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4443:            if(bool==1){
                   4444:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4445:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4446:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4447:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4448:              if(m >=firstpass && m <=lastpass){
                   4449:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4450:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4451:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4452:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4453:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4454:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4455:                if (m<lastpass) {
                   4456:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4457:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4458:                  if(s[m][iind]==-1)
                   4459:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4460:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4461:                  /* if((int)agev[m][iind] == 55) */
                   4462:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4463:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4464:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4465:                }
1.251     brouard  4466:              } /* end if between passes */  
                   4467:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4468:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4469:                k2cpt++;
                   4470:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4471:              }
1.251     brouard  4472:            }else{
                   4473:              bool=1;
                   4474:            }/* end bool 2 */
                   4475:          } /* end m */
                   4476:        } /* end bool */
                   4477:       } /* end iind = 1 to imx */
                   4478:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4479:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4480:       
                   4481:       
                   4482:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
                   4483:       pstamp(ficresp);
                   4484:       if  (cptcoveff>0 && j!=0){
                   4485:        printf( "\n#********** Variable "); 
                   4486:        fprintf(ficresp, "\n#********** Variable "); 
                   4487:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4488:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4489:        fprintf(ficlog, "\n#********** Variable "); 
                   4490:        for (z1=1; z1<=cptcoveff; z1++){
                   4491:          if(!FixedV[Tvaraff[z1]]){
                   4492:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4493:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4494:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4495:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4496:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4497:          }else{
1.251     brouard  4498:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4499:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4500:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4501:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4502:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4503:          }
                   4504:        }
                   4505:        printf( "**********\n#");
                   4506:        fprintf(ficresp, "**********\n#");
                   4507:        fprintf(ficresphtm, "**********</h3>\n");
                   4508:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4509:        fprintf(ficlog, "**********\n");
                   4510:       }
                   4511:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
                   4512:       for(i=1; i<=nlstate;i++) {
                   4513:        fprintf(ficresp, " Age Prev(%d)  N(%d)  N  ",i,i);
                   4514:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4515:       }
                   4516:       fprintf(ficresp, "\n");
                   4517:       fprintf(ficresphtm, "\n");
                   4518:       
                   4519:       /* Header of frequency table by age */
                   4520:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4521:       fprintf(ficresphtmfr,"<th>Age</th> ");
                   4522:       for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4523:        for(m=-1; m <=nlstate+ndeath; m++){
                   4524:          if(jk!=0 && m!=0)
                   4525:            fprintf(ficresphtmfr,"<th>%d%d</th> ",jk,m);
1.240     brouard  4526:        }
1.226     brouard  4527:       }
1.251     brouard  4528:       fprintf(ficresphtmfr, "\n");
                   4529:     
                   4530:       /* For each age */
                   4531:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4532:        fprintf(ficresphtm,"<tr>");
                   4533:        if(iage==iagemax+1){
                   4534:          fprintf(ficlog,"1");
                   4535:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4536:        }else if(iage==iagemax+2){
                   4537:          fprintf(ficlog,"0");
                   4538:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4539:        }else if(iage==iagemax+3){
                   4540:          fprintf(ficlog,"Total");
                   4541:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4542:        }else{
1.240     brouard  4543:          if(first==1){
1.251     brouard  4544:            first=0;
                   4545:            printf("See log file for details...\n");
                   4546:          }
                   4547:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4548:          fprintf(ficlog,"Age %d", iage);
                   4549:        }
                   4550:        for(jk=1; jk <=nlstate ; jk++){
                   4551:          for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
                   4552:            pp[jk] += freq[jk][m][iage]; 
                   4553:        }
                   4554:        for(jk=1; jk <=nlstate ; jk++){
                   4555:          for(m=-1, pos=0; m <=0 ; m++)
                   4556:            pos += freq[jk][m][iage];
                   4557:          if(pp[jk]>=1.e-10){
                   4558:            if(first==1){
                   4559:              printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4560:            }
                   4561:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4562:          }else{
                   4563:            if(first==1)
                   4564:              printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
                   4565:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
1.240     brouard  4566:          }
                   4567:        }
                   4568:       
1.251     brouard  4569:        for(jk=1; jk <=nlstate ; jk++){ 
                   4570:          /* posprop[jk]=0; */
                   4571:          for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4572:            pp[jk] += freq[jk][m][iage];
                   4573:        }       /* pp[jk] is the total number of transitions starting from state jk and any ending status until this age */
                   4574:       
                   4575:        for(jk=1,pos=0, pospropta=0.; jk <=nlstate ; jk++){
                   4576:          pos += pp[jk]; /* pos is the total number of transitions until this age */
                   4577:          posprop[jk] += prop[jk][iage]; /* prop is the number of transitions from a live state
                   4578:                                            from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4579:          pospropta += prop[jk][iage]; /* prop is the number of transitions from a live state
1.240     brouard  4580:                                          from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4581:        }
1.251     brouard  4582:        for(jk=1; jk <=nlstate ; jk++){
1.240     brouard  4583:          if(pos>=1.e-5){
1.251     brouard  4584:            if(first==1)
                   4585:              printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4586:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4587:          }else{
                   4588:            if(first==1)
                   4589:              printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4590:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4591:          }
                   4592:          if( iage <= iagemax){
                   4593:            if(pos>=1.e-5){
                   4594:              fprintf(ficresp," %d %.5f %.0f %.0f",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4595:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4596:              /*probs[iage][jk][j1]= pp[jk]/pos;*/
                   4597:              /*printf("\niage=%d jk=%d j1=%d %.5f %.0f %.0f %f",iage,jk,j1,pp[jk]/pos, pp[jk],pos,probs[iage][jk][j1]);*/
                   4598:            }
                   4599:            else{
                   4600:              fprintf(ficresp," %d NaNq %.0f %.0f",iage,prop[jk][iage],pospropta);
                   4601:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[jk][iage],pospropta);
                   4602:            }
1.240     brouard  4603:          }
1.251     brouard  4604:          pospropt[jk] +=posprop[jk];
                   4605:        } /* end loop jk */
                   4606:        /* pospropt=0.; */
                   4607:        for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4608:          for(m=-1; m <=nlstate+ndeath; m++){
                   4609:            if(freq[jk][m][iage] !=0 ) { /* minimizing output */
                   4610:              if(first==1){
                   4611:                printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4612:              }
1.253     brouard  4613:              /* printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]); */
1.251     brouard  4614:              fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4615:            }
                   4616:            if(jk!=0 && m!=0)
                   4617:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[jk][m][iage]);
1.240     brouard  4618:          }
1.251     brouard  4619:        } /* end loop jk */
                   4620:        posproptt=0.; 
                   4621:        for(jk=1; jk <=nlstate; jk++){
                   4622:          posproptt += pospropt[jk];
                   4623:        }
                   4624:        fprintf(ficresphtmfr,"</tr>\n ");
                   4625:        if(iage <= iagemax){
                   4626:          fprintf(ficresp,"\n");
                   4627:          fprintf(ficresphtm,"</tr>\n");
1.240     brouard  4628:        }
1.251     brouard  4629:        if(first==1)
                   4630:          printf("Others in log...\n");
                   4631:        fprintf(ficlog,"\n");
                   4632:       } /* end loop age iage */
                   4633:       fprintf(ficresphtm,"<tr><th>Tot</th>");
                   4634:       for(jk=1; jk <=nlstate ; jk++){
                   4635:        if(posproptt < 1.e-5){
                   4636:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[jk],posproptt); 
                   4637:        }else{
                   4638:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[jk]/posproptt,pospropt[jk],posproptt);  
1.240     brouard  4639:        }
1.226     brouard  4640:       }
1.251     brouard  4641:       fprintf(ficresphtm,"</tr>\n");
                   4642:       fprintf(ficresphtm,"</table>\n");
                   4643:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4644:       if(posproptt < 1.e-5){
1.251     brouard  4645:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4646:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4647:        fprintf(ficres,"\n  This combination (%d) is not valid and no result will be produced\n\n",j1);
                   4648:        invalidvarcomb[j1]=1;
1.226     brouard  4649:       }else{
1.251     brouard  4650:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4651:        invalidvarcomb[j1]=0;
1.226     brouard  4652:       }
1.251     brouard  4653:       fprintf(ficresphtmfr,"</table>\n");
                   4654:       fprintf(ficlog,"\n");
                   4655:       if(j!=0){
                   4656:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
                   4657:        for(i=1,jk=1; i <=nlstate; i++){
                   4658:          for(k=1; k <=(nlstate+ndeath); k++){
                   4659:            if (k != i) {
                   4660:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting jk */
1.253     brouard  4661:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4662:                  if(j1==1){ /* All dummy covariates to zero */
                   4663:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4664:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4665:                    printf("%d%d ",i,k);
                   4666:                    fprintf(ficlog,"%d%d ",i,k);
                   4667:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4668:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4669:                    pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4670:                  }
1.253     brouard  4671:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4672:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4673:                    x[iage]= (double)iage;
                   4674:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
                   4675:                    /* printf("i=%d, k=%d, jk=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,jk,j1,jj, iage, y[iage]); */
                   4676:                  }
                   4677:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
                   4678:                  pstart[jk]=b;
                   4679:                  pstart[jk-1]=a;
1.252     brouard  4680:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4681:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4682:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.251     brouard  4683:                  pstart[jk]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4684:                  printf("%d%d ",i,k);
                   4685:                  fprintf(ficlog,"%d%d ",i,k);
1.251     brouard  4686:                  printf("jk=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",jk,i,k,jk,p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
                   4687:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4688:                  ;
                   4689:                }
                   4690:                /* printf("%12.7f )", param[i][jj][k]); */
                   4691:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
                   4692:                jk++; 
                   4693:              } /* end jj */
                   4694:            } /* end k!= i */
                   4695:          } /* end k */
                   4696:        } /* end i, jk */
                   4697:       } /* end j !=0 */
                   4698:     } /* end selected combination of covariate j1 */
                   4699:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4700:       printf("#Freqsummary: Starting values for the constants:\n");
                   4701:       fprintf(ficlog,"\n");
                   4702:       for(i=1,jk=1; i <=nlstate; i++){
                   4703:        for(k=1; k <=(nlstate+ndeath); k++){
                   4704:          if (k != i) {
                   4705:            printf("%d%d ",i,k);
                   4706:            fprintf(ficlog,"%d%d ",i,k);
                   4707:            for(jj=1; jj <=ncovmodel; jj++){
1.253     brouard  4708:              pstart[jk]=p[jk]; /* Setting pstart to p values by default */
                   4709:              if(jj==1){ /* Age has to be done */
                   4710:                pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4711:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4712:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4713:              }
                   4714:              /* printf("%12.7f )", param[i][jj][k]); */
                   4715:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
                   4716:              jk++; 
1.250     brouard  4717:            }
1.251     brouard  4718:            printf("\n");
                   4719:            fprintf(ficlog,"\n");
1.250     brouard  4720:          }
                   4721:        }
                   4722:       }
1.251     brouard  4723:       printf("#Freqsummary\n");
                   4724:       fprintf(ficlog,"\n");
                   4725:       for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4726:        for(m=-1; m <=nlstate+ndeath; m++){
                   4727:          /* param[i]|j][k]= freq[jk][m][iagemax+3] */
1.250     brouard  4728:          printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
                   4729:          fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
1.251     brouard  4730:          /* if(freq[jk][m][iage] !=0 ) { /\* minimizing output *\/ */
                   4731:          /*   printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
                   4732:          /*   fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
                   4733:          /* } */
                   4734:        }
                   4735:       } /* end loop jk */
                   4736:       
                   4737:       printf("\n");
                   4738:       fprintf(ficlog,"\n");
                   4739:     } /* end j=0 */
1.249     brouard  4740:   } /* end j */
1.252     brouard  4741: 
1.253     brouard  4742:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4743:     for(i=1, jk=1; i <=nlstate; i++){
                   4744:       for(j=1; j <=nlstate+ndeath; j++){
                   4745:        if(j!=i){
                   4746:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4747:          printf("%1d%1d",i,j);
                   4748:          fprintf(ficparo,"%1d%1d",i,j);
                   4749:          for(k=1; k<=ncovmodel;k++){
                   4750:            /*    printf(" %lf",param[i][j][k]); */
                   4751:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4752:            p[jk]=pstart[jk];
                   4753:            printf(" %f ",pstart[jk]);
                   4754:            fprintf(ficparo," %f ",pstart[jk]);
                   4755:            jk++;
                   4756:          }
                   4757:          printf("\n");
                   4758:          fprintf(ficparo,"\n");
                   4759:        }
                   4760:       }
                   4761:     }
                   4762:   } /* end mle=-2 */
1.226     brouard  4763:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4764:   
1.226     brouard  4765:   fclose(ficresp);
                   4766:   fclose(ficresphtm);
                   4767:   fclose(ficresphtmfr);
                   4768:   free_vector(meanq,1,nqfveff);
                   4769:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4770:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4771:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4772:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4773:   free_vector(pospropt,1,nlstate);
                   4774:   free_vector(posprop,1,nlstate);
1.251     brouard  4775:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4776:   free_vector(pp,1,nlstate);
                   4777:   /* End of freqsummary */
                   4778: }
1.126     brouard  4779: 
                   4780: /************ Prevalence ********************/
1.227     brouard  4781: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4782: {  
                   4783:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4784:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4785:      We still use firstpass and lastpass as another selection.
                   4786:   */
1.126     brouard  4787:  
1.227     brouard  4788:   int i, m, jk, j1, bool, z1,j, iv;
                   4789:   int mi; /* Effective wave */
                   4790:   int iage;
                   4791:   double agebegin, ageend;
                   4792: 
                   4793:   double **prop;
                   4794:   double posprop; 
                   4795:   double  y2; /* in fractional years */
                   4796:   int iagemin, iagemax;
                   4797:   int first; /** to stop verbosity which is redirected to log file */
                   4798: 
                   4799:   iagemin= (int) agemin;
                   4800:   iagemax= (int) agemax;
                   4801:   /*pp=vector(1,nlstate);*/
1.251     brouard  4802:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  4803:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4804:   j1=0;
1.222     brouard  4805:   
1.227     brouard  4806:   /*j=cptcoveff;*/
                   4807:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4808:   
1.227     brouard  4809:   first=1;
                   4810:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4811:     for (i=1; i<=nlstate; i++)  
1.251     brouard  4812:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  4813:        prop[i][iage]=0.0;
                   4814:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4815:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4816:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4817:     
                   4818:     for (i=1; i<=imx; i++) { /* Each individual */
                   4819:       bool=1;
                   4820:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4821:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4822:        m=mw[mi][i];
                   4823:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4824:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4825:        for (z1=1; z1<=cptcoveff; z1++){
                   4826:          if( Fixed[Tmodelind[z1]]==1){
                   4827:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4828:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4829:              bool=0;
                   4830:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4831:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4832:              bool=0;
                   4833:            }
                   4834:        }
                   4835:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4836:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4837:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4838:          if(m >=firstpass && m <=lastpass){
                   4839:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4840:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4841:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   4842:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  4843:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  4844:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   4845:                exit(1);
                   4846:              }
                   4847:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   4848:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   4849:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   4850:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   4851:              } /* end valid statuses */ 
                   4852:            } /* end selection of dates */
                   4853:          } /* end selection of waves */
                   4854:        } /* end bool */
                   4855:       } /* end wave */
                   4856:     } /* end individual */
                   4857:     for(i=iagemin; i <= iagemax+3; i++){  
                   4858:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   4859:        posprop += prop[jk][i]; 
                   4860:       } 
                   4861:       
                   4862:       for(jk=1; jk <=nlstate ; jk++){      
                   4863:        if( i <=  iagemax){ 
                   4864:          if(posprop>=1.e-5){ 
                   4865:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   4866:          } else{
                   4867:            if(first==1){
                   4868:              first=0;
                   4869:              printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,j1,probs[i][jk][j1]);
                   4870:            }
                   4871:          }
                   4872:        } 
                   4873:       }/* end jk */ 
                   4874:     }/* end i */ 
1.222     brouard  4875:      /*} *//* end i1 */
1.227     brouard  4876:   } /* end j1 */
1.222     brouard  4877:   
1.227     brouard  4878:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   4879:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  4880:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  4881: }  /* End of prevalence */
1.126     brouard  4882: 
                   4883: /************* Waves Concatenation ***************/
                   4884: 
                   4885: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   4886: {
                   4887:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   4888:      Death is a valid wave (if date is known).
                   4889:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   4890:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4891:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  4892:   */
1.126     brouard  4893: 
1.224     brouard  4894:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  4895:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   4896:      double sum=0., jmean=0.;*/
1.224     brouard  4897:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  4898:   int j, k=0,jk, ju, jl;
                   4899:   double sum=0.;
                   4900:   first=0;
1.214     brouard  4901:   firstwo=0;
1.217     brouard  4902:   firsthree=0;
1.218     brouard  4903:   firstfour=0;
1.164     brouard  4904:   jmin=100000;
1.126     brouard  4905:   jmax=-1;
                   4906:   jmean=0.;
1.224     brouard  4907: 
                   4908: /* Treating live states */
1.214     brouard  4909:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  4910:     mi=0;  /* First valid wave */
1.227     brouard  4911:     mli=0; /* Last valid wave */
1.126     brouard  4912:     m=firstpass;
1.214     brouard  4913:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  4914:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   4915:        mli=m-1;/* mw[++mi][i]=m-1; */
                   4916:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   4917:        mw[++mi][i]=m;
                   4918:        mli=m;
1.224     brouard  4919:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   4920:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  4921:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  4922:       }
1.227     brouard  4923:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  4924: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  4925:        break;
1.224     brouard  4926: #else
1.227     brouard  4927:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   4928:          if(firsthree == 0){
                   4929:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4930:            firsthree=1;
                   4931:          }
                   4932:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4933:          mw[++mi][i]=m;
                   4934:          mli=m;
                   4935:        }
                   4936:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   4937:          nbwarn++;
                   4938:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   4939:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4940:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4941:          }
                   4942:          break;
                   4943:        }
                   4944:        break;
1.224     brouard  4945: #endif
1.227     brouard  4946:       }/* End m >= lastpass */
1.126     brouard  4947:     }/* end while */
1.224     brouard  4948: 
1.227     brouard  4949:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  4950:     /* After last pass */
1.224     brouard  4951: /* Treating death states */
1.214     brouard  4952:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  4953:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   4954:       /* } */
1.126     brouard  4955:       mi++;    /* Death is another wave */
                   4956:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  4957:       /* Only death is a correct wave */
1.126     brouard  4958:       mw[mi][i]=m;
1.224     brouard  4959:     }
                   4960: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.227     brouard  4961:     else if ((int) andc[i] != 9999) { /* Status is negative. A death occured after lastpass, we can't take it into account because of potential bias */
1.216     brouard  4962:       /* m++; */
                   4963:       /* mi++; */
                   4964:       /* s[m][i]=nlstate+1;  /\* We are setting the status to the last of non live state *\/ */
                   4965:       /* mw[mi][i]=m; */
1.218     brouard  4966:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  4967:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   4968:          nbwarn++;
                   4969:          if(firstfiv==0){
                   4970:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4971:            firstfiv=1;
                   4972:          }else{
                   4973:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4974:          }
                   4975:        }else{ /* Death occured afer last wave potential bias */
                   4976:          nberr++;
                   4977:          if(firstwo==0){
                   4978:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4979:            firstwo=1;
                   4980:          }
                   4981:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4982:        }
1.218     brouard  4983:       }else{ /* end date of interview is known */
1.227     brouard  4984:        /* death is known but not confirmed by death status at any wave */
                   4985:        if(firstfour==0){
                   4986:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4987:          firstfour=1;
                   4988:        }
                   4989:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  4990:       }
1.224     brouard  4991:     } /* end if date of death is known */
                   4992: #endif
                   4993:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   4994:     /* wav[i]=mw[mi][i]; */
1.126     brouard  4995:     if(mi==0){
                   4996:       nbwarn++;
                   4997:       if(first==0){
1.227     brouard  4998:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   4999:        first=1;
1.126     brouard  5000:       }
                   5001:       if(first==1){
1.227     brouard  5002:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5003:       }
                   5004:     } /* end mi==0 */
                   5005:   } /* End individuals */
1.214     brouard  5006:   /* wav and mw are no more changed */
1.223     brouard  5007:        
1.214     brouard  5008:   
1.126     brouard  5009:   for(i=1; i<=imx; i++){
                   5010:     for(mi=1; mi<wav[i];mi++){
                   5011:       if (stepm <=0)
1.227     brouard  5012:        dh[mi][i]=1;
1.126     brouard  5013:       else{
1.227     brouard  5014:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death */
                   5015:          if (agedc[i] < 2*AGESUP) {
                   5016:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5017:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5018:            else if(j<0){
                   5019:              nberr++;
                   5020:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5021:              j=1; /* Temporary Dangerous patch */
                   5022:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5023:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5024:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5025:            }
                   5026:            k=k+1;
                   5027:            if (j >= jmax){
                   5028:              jmax=j;
                   5029:              ijmax=i;
                   5030:            }
                   5031:            if (j <= jmin){
                   5032:              jmin=j;
                   5033:              ijmin=i;
                   5034:            }
                   5035:            sum=sum+j;
                   5036:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5037:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5038:          }
                   5039:        }
                   5040:        else{
                   5041:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5042: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5043:                                        
1.227     brouard  5044:          k=k+1;
                   5045:          if (j >= jmax) {
                   5046:            jmax=j;
                   5047:            ijmax=i;
                   5048:          }
                   5049:          else if (j <= jmin){
                   5050:            jmin=j;
                   5051:            ijmin=i;
                   5052:          }
                   5053:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5054:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5055:          if(j<0){
                   5056:            nberr++;
                   5057:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5058:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5059:          }
                   5060:          sum=sum+j;
                   5061:        }
                   5062:        jk= j/stepm;
                   5063:        jl= j -jk*stepm;
                   5064:        ju= j -(jk+1)*stepm;
                   5065:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5066:          if(jl==0){
                   5067:            dh[mi][i]=jk;
                   5068:            bh[mi][i]=0;
                   5069:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5070:                  * to avoid the price of an extra matrix product in likelihood */
                   5071:            dh[mi][i]=jk+1;
                   5072:            bh[mi][i]=ju;
                   5073:          }
                   5074:        }else{
                   5075:          if(jl <= -ju){
                   5076:            dh[mi][i]=jk;
                   5077:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5078:                                 * is higher than the multiple of stepm and negative otherwise.
                   5079:                                 */
                   5080:          }
                   5081:          else{
                   5082:            dh[mi][i]=jk+1;
                   5083:            bh[mi][i]=ju;
                   5084:          }
                   5085:          if(dh[mi][i]==0){
                   5086:            dh[mi][i]=1; /* At least one step */
                   5087:            bh[mi][i]=ju; /* At least one step */
                   5088:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5089:          }
                   5090:        } /* end if mle */
1.126     brouard  5091:       }
                   5092:     } /* end wave */
                   5093:   }
                   5094:   jmean=sum/k;
                   5095:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5096:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5097: }
1.126     brouard  5098: 
                   5099: /*********** Tricode ****************************/
1.220     brouard  5100:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5101:  {
                   5102:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5103:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5104:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5105:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5106:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5107:     */
1.130     brouard  5108: 
1.242     brouard  5109:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5110:    int modmaxcovj=0; /* Modality max of covariates j */
                   5111:    int cptcode=0; /* Modality max of covariates j */
                   5112:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5113: 
                   5114: 
1.242     brouard  5115:    /* cptcoveff=0;  */
                   5116:    /* *cptcov=0; */
1.126     brouard  5117:  
1.242     brouard  5118:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  5119: 
1.242     brouard  5120:    /* Loop on covariates without age and products and no quantitative variable */
                   5121:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5122:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5123:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5124:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5125:        switch(Fixed[k]) {
                   5126:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5127:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5128:           ij=(int)(covar[Tvar[k]][i]);
                   5129:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5130:            * If product of Vn*Vm, still boolean *:
                   5131:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5132:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5133:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5134:              modality of the nth covariate of individual i. */
                   5135:           if (ij > modmaxcovj)
                   5136:             modmaxcovj=ij; 
                   5137:           else if (ij < modmincovj) 
                   5138:             modmincovj=ij; 
                   5139:           if ((ij < -1) && (ij > NCOVMAX)){
                   5140:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5141:             exit(1);
                   5142:           }else
                   5143:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5144:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5145:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5146:           /* getting the maximum value of the modality of the covariate
                   5147:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5148:              female ies 1, then modmaxcovj=1.
                   5149:           */
                   5150:         } /* end for loop on individuals i */
                   5151:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5152:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5153:         cptcode=modmaxcovj;
                   5154:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5155:         /*for (i=0; i<=cptcode; i++) {*/
                   5156:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5157:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5158:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5159:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5160:             if( j != -1){
                   5161:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5162:                                  covariate for which somebody answered excluding 
                   5163:                                  undefined. Usually 2: 0 and 1. */
                   5164:             }
                   5165:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5166:                                     covariate for which somebody answered including 
                   5167:                                     undefined. Usually 3: -1, 0 and 1. */
                   5168:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5169:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5170:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5171:                        
1.242     brouard  5172:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5173:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5174:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5175:         /* modmincovj=3; modmaxcovj = 7; */
                   5176:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5177:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5178:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5179:         /* nbcode[Tvar[j]][ij]=k; */
                   5180:         /* nbcode[Tvar[j]][1]=0; */
                   5181:         /* nbcode[Tvar[j]][2]=1; */
                   5182:         /* nbcode[Tvar[j]][3]=2; */
                   5183:         /* To be continued (not working yet). */
                   5184:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5185:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5186:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5187:             break;
                   5188:           }
                   5189:           ij++;
                   5190:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5191:           cptcode = ij; /* New max modality for covar j */
                   5192:         } /* end of loop on modality i=-1 to 1 or more */
                   5193:         break;
                   5194:        case 1: /* Testing on varying covariate, could be simple and
                   5195:                * should look at waves or product of fixed *
                   5196:                * varying. No time to test -1, assuming 0 and 1 only */
                   5197:         ij=0;
                   5198:         for(i=0; i<=1;i++){
                   5199:           nbcode[Tvar[k]][++ij]=i;
                   5200:         }
                   5201:         break;
                   5202:        default:
                   5203:         break;
                   5204:        } /* end switch */
                   5205:      } /* end dummy test */
                   5206:     
                   5207:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5208:      /*        /\*recode from 0 *\/ */
                   5209:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5210:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5211:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5212:      /*        } */
                   5213:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5214:      /*        if (ij > ncodemax[j]) { */
                   5215:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5216:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5217:      /*          break; */
                   5218:      /*        } */
                   5219:      /*   }  /\* end of loop on modality k *\/ */
                   5220:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5221:   
                   5222:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5223:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5224:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5225:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5226:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5227:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5228:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5229:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5230:   
                   5231:    ij=0;
                   5232:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5233:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5234:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5235:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5236:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5237:        /* If product not in single variable we don't print results */
                   5238:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5239:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5240:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5241:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5242:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5243:        if(Fixed[k]!=0)
                   5244:         anyvaryingduminmodel=1;
                   5245:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5246:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5247:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5248:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5249:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5250:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5251:      } 
                   5252:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5253:    /* ij--; */
                   5254:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5255:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5256:                * because they can be excluded from the model and real
                   5257:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5258:    for(j=ij+1; j<= cptcovt; j++){
                   5259:      Tvaraff[j]=0;
                   5260:      Tmodelind[j]=0;
                   5261:    }
                   5262:    for(j=ntveff+1; j<= cptcovt; j++){
                   5263:      TmodelInvind[j]=0;
                   5264:    }
                   5265:    /* To be sorted */
                   5266:    ;
                   5267:  }
1.126     brouard  5268: 
1.145     brouard  5269: 
1.126     brouard  5270: /*********** Health Expectancies ****************/
                   5271: 
1.235     brouard  5272:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5273: 
                   5274: {
                   5275:   /* Health expectancies, no variances */
1.164     brouard  5276:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5277:   int nhstepma, nstepma; /* Decreasing with age */
                   5278:   double age, agelim, hf;
                   5279:   double ***p3mat;
                   5280:   double eip;
                   5281: 
1.238     brouard  5282:   /* pstamp(ficreseij); */
1.126     brouard  5283:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5284:   fprintf(ficreseij,"# Age");
                   5285:   for(i=1; i<=nlstate;i++){
                   5286:     for(j=1; j<=nlstate;j++){
                   5287:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5288:     }
                   5289:     fprintf(ficreseij," e%1d. ",i);
                   5290:   }
                   5291:   fprintf(ficreseij,"\n");
                   5292: 
                   5293:   
                   5294:   if(estepm < stepm){
                   5295:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5296:   }
                   5297:   else  hstepm=estepm;   
                   5298:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5299:    * This is mainly to measure the difference between two models: for example
                   5300:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5301:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5302:    * progression in between and thus overestimating or underestimating according
                   5303:    * to the curvature of the survival function. If, for the same date, we 
                   5304:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5305:    * to compare the new estimate of Life expectancy with the same linear 
                   5306:    * hypothesis. A more precise result, taking into account a more precise
                   5307:    * curvature will be obtained if estepm is as small as stepm. */
                   5308: 
                   5309:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5310:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5311:      nhstepm is the number of hstepm from age to agelim 
                   5312:      nstepm is the number of stepm from age to agelin. 
                   5313:      Look at hpijx to understand the reason of that which relies in memory size
                   5314:      and note for a fixed period like estepm months */
                   5315:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5316:      survival function given by stepm (the optimization length). Unfortunately it
                   5317:      means that if the survival funtion is printed only each two years of age and if
                   5318:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5319:      results. So we changed our mind and took the option of the best precision.
                   5320:   */
                   5321:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5322: 
                   5323:   agelim=AGESUP;
                   5324:   /* If stepm=6 months */
                   5325:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5326:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5327:     
                   5328: /* nhstepm age range expressed in number of stepm */
                   5329:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5330:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5331:   /* if (stepm >= YEARM) hstepm=1;*/
                   5332:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5333:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5334: 
                   5335:   for (age=bage; age<=fage; age ++){ 
                   5336:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5337:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5338:     /* if (stepm >= YEARM) hstepm=1;*/
                   5339:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5340: 
                   5341:     /* If stepm=6 months */
                   5342:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5343:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5344:     
1.235     brouard  5345:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5346:     
                   5347:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5348:     
                   5349:     printf("%d|",(int)age);fflush(stdout);
                   5350:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5351:     
                   5352:     /* Computing expectancies */
                   5353:     for(i=1; i<=nlstate;i++)
                   5354:       for(j=1; j<=nlstate;j++)
                   5355:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5356:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5357:          
                   5358:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5359: 
                   5360:        }
                   5361: 
                   5362:     fprintf(ficreseij,"%3.0f",age );
                   5363:     for(i=1; i<=nlstate;i++){
                   5364:       eip=0;
                   5365:       for(j=1; j<=nlstate;j++){
                   5366:        eip +=eij[i][j][(int)age];
                   5367:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5368:       }
                   5369:       fprintf(ficreseij,"%9.4f", eip );
                   5370:     }
                   5371:     fprintf(ficreseij,"\n");
                   5372:     
                   5373:   }
                   5374:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5375:   printf("\n");
                   5376:   fprintf(ficlog,"\n");
                   5377:   
                   5378: }
                   5379: 
1.235     brouard  5380:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5381: 
                   5382: {
                   5383:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5384:      to initial status i, ei. .
1.126     brouard  5385:   */
                   5386:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5387:   int nhstepma, nstepma; /* Decreasing with age */
                   5388:   double age, agelim, hf;
                   5389:   double ***p3matp, ***p3matm, ***varhe;
                   5390:   double **dnewm,**doldm;
                   5391:   double *xp, *xm;
                   5392:   double **gp, **gm;
                   5393:   double ***gradg, ***trgradg;
                   5394:   int theta;
                   5395: 
                   5396:   double eip, vip;
                   5397: 
                   5398:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5399:   xp=vector(1,npar);
                   5400:   xm=vector(1,npar);
                   5401:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5402:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5403:   
                   5404:   pstamp(ficresstdeij);
                   5405:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5406:   fprintf(ficresstdeij,"# Age");
                   5407:   for(i=1; i<=nlstate;i++){
                   5408:     for(j=1; j<=nlstate;j++)
                   5409:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5410:     fprintf(ficresstdeij," e%1d. ",i);
                   5411:   }
                   5412:   fprintf(ficresstdeij,"\n");
                   5413: 
                   5414:   pstamp(ficrescveij);
                   5415:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5416:   fprintf(ficrescveij,"# Age");
                   5417:   for(i=1; i<=nlstate;i++)
                   5418:     for(j=1; j<=nlstate;j++){
                   5419:       cptj= (j-1)*nlstate+i;
                   5420:       for(i2=1; i2<=nlstate;i2++)
                   5421:        for(j2=1; j2<=nlstate;j2++){
                   5422:          cptj2= (j2-1)*nlstate+i2;
                   5423:          if(cptj2 <= cptj)
                   5424:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5425:        }
                   5426:     }
                   5427:   fprintf(ficrescveij,"\n");
                   5428:   
                   5429:   if(estepm < stepm){
                   5430:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5431:   }
                   5432:   else  hstepm=estepm;   
                   5433:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5434:    * This is mainly to measure the difference between two models: for example
                   5435:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5436:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5437:    * progression in between and thus overestimating or underestimating according
                   5438:    * to the curvature of the survival function. If, for the same date, we 
                   5439:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5440:    * to compare the new estimate of Life expectancy with the same linear 
                   5441:    * hypothesis. A more precise result, taking into account a more precise
                   5442:    * curvature will be obtained if estepm is as small as stepm. */
                   5443: 
                   5444:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5445:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5446:      nhstepm is the number of hstepm from age to agelim 
                   5447:      nstepm is the number of stepm from age to agelin. 
                   5448:      Look at hpijx to understand the reason of that which relies in memory size
                   5449:      and note for a fixed period like estepm months */
                   5450:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5451:      survival function given by stepm (the optimization length). Unfortunately it
                   5452:      means that if the survival funtion is printed only each two years of age and if
                   5453:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5454:      results. So we changed our mind and took the option of the best precision.
                   5455:   */
                   5456:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5457: 
                   5458:   /* If stepm=6 months */
                   5459:   /* nhstepm age range expressed in number of stepm */
                   5460:   agelim=AGESUP;
                   5461:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5462:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5463:   /* if (stepm >= YEARM) hstepm=1;*/
                   5464:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5465:   
                   5466:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5467:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5468:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5469:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5470:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5471:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5472: 
                   5473:   for (age=bage; age<=fage; age ++){ 
                   5474:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5475:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5476:     /* if (stepm >= YEARM) hstepm=1;*/
                   5477:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5478:                
1.126     brouard  5479:     /* If stepm=6 months */
                   5480:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5481:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5482:     
                   5483:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5484:                
1.126     brouard  5485:     /* Computing  Variances of health expectancies */
                   5486:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5487:        decrease memory allocation */
                   5488:     for(theta=1; theta <=npar; theta++){
                   5489:       for(i=1; i<=npar; i++){ 
1.222     brouard  5490:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5491:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5492:       }
1.235     brouard  5493:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5494:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5495:                        
1.126     brouard  5496:       for(j=1; j<= nlstate; j++){
1.222     brouard  5497:        for(i=1; i<=nlstate; i++){
                   5498:          for(h=0; h<=nhstepm-1; h++){
                   5499:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5500:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5501:          }
                   5502:        }
1.126     brouard  5503:       }
1.218     brouard  5504:                        
1.126     brouard  5505:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5506:        for(h=0; h<=nhstepm-1; h++){
                   5507:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5508:        }
1.126     brouard  5509:     }/* End theta */
                   5510:     
                   5511:     
                   5512:     for(h=0; h<=nhstepm-1; h++)
                   5513:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5514:        for(theta=1; theta <=npar; theta++)
                   5515:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5516:     
1.218     brouard  5517:                
1.222     brouard  5518:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5519:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5520:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5521:                
1.222     brouard  5522:     printf("%d|",(int)age);fflush(stdout);
                   5523:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5524:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5525:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5526:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5527:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5528:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5529:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5530:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5531:       }
                   5532:     }
1.218     brouard  5533:                
1.126     brouard  5534:     /* Computing expectancies */
1.235     brouard  5535:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5536:     for(i=1; i<=nlstate;i++)
                   5537:       for(j=1; j<=nlstate;j++)
1.222     brouard  5538:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5539:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5540:                                        
1.222     brouard  5541:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5542:                                        
1.222     brouard  5543:        }
1.218     brouard  5544:                
1.126     brouard  5545:     fprintf(ficresstdeij,"%3.0f",age );
                   5546:     for(i=1; i<=nlstate;i++){
                   5547:       eip=0.;
                   5548:       vip=0.;
                   5549:       for(j=1; j<=nlstate;j++){
1.222     brouard  5550:        eip += eij[i][j][(int)age];
                   5551:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5552:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5553:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5554:       }
                   5555:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5556:     }
                   5557:     fprintf(ficresstdeij,"\n");
1.218     brouard  5558:                
1.126     brouard  5559:     fprintf(ficrescveij,"%3.0f",age );
                   5560:     for(i=1; i<=nlstate;i++)
                   5561:       for(j=1; j<=nlstate;j++){
1.222     brouard  5562:        cptj= (j-1)*nlstate+i;
                   5563:        for(i2=1; i2<=nlstate;i2++)
                   5564:          for(j2=1; j2<=nlstate;j2++){
                   5565:            cptj2= (j2-1)*nlstate+i2;
                   5566:            if(cptj2 <= cptj)
                   5567:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5568:          }
1.126     brouard  5569:       }
                   5570:     fprintf(ficrescveij,"\n");
1.218     brouard  5571:                
1.126     brouard  5572:   }
                   5573:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5574:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5575:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5576:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5577:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5578:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5579:   printf("\n");
                   5580:   fprintf(ficlog,"\n");
1.218     brouard  5581:        
1.126     brouard  5582:   free_vector(xm,1,npar);
                   5583:   free_vector(xp,1,npar);
                   5584:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5585:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5586:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5587: }
1.218     brouard  5588:  
1.126     brouard  5589: /************ Variance ******************/
1.235     brouard  5590:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5591:  {
                   5592:    /* Variance of health expectancies */
                   5593:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5594:    /* double **newm;*/
                   5595:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5596:   
                   5597:    /* int movingaverage(); */
                   5598:    double **dnewm,**doldm;
                   5599:    double **dnewmp,**doldmp;
                   5600:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5601:    int k;
                   5602:    double *xp;
                   5603:    double **gp, **gm;  /* for var eij */
                   5604:    double ***gradg, ***trgradg; /*for var eij */
                   5605:    double **gradgp, **trgradgp; /* for var p point j */
                   5606:    double *gpp, *gmp; /* for var p point j */
                   5607:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5608:    double ***p3mat;
                   5609:    double age,agelim, hf;
                   5610:    /* double ***mobaverage; */
                   5611:    int theta;
                   5612:    char digit[4];
                   5613:    char digitp[25];
                   5614: 
                   5615:    char fileresprobmorprev[FILENAMELENGTH];
                   5616: 
                   5617:    if(popbased==1){
                   5618:      if(mobilav!=0)
                   5619:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5620:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5621:    }
                   5622:    else 
                   5623:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5624: 
1.218     brouard  5625:    /* if (mobilav!=0) { */
                   5626:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5627:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5628:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5629:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5630:    /*   } */
                   5631:    /* } */
                   5632: 
                   5633:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5634:    sprintf(digit,"%-d",ij);
                   5635:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5636:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5637:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5638:    strcat(fileresprobmorprev,fileresu);
                   5639:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5640:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5641:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5642:    }
                   5643:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5644:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5645:    pstamp(ficresprobmorprev);
                   5646:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5647:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5648:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5649:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5650:    }
                   5651:    for(j=1;j<=cptcoveff;j++) 
                   5652:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5653:    fprintf(ficresprobmorprev,"\n");
                   5654: 
1.218     brouard  5655:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5656:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5657:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5658:      for(i=1; i<=nlstate;i++)
                   5659:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5660:    }  
                   5661:    fprintf(ficresprobmorprev,"\n");
                   5662:   
                   5663:    fprintf(ficgp,"\n# Routine varevsij");
                   5664:    fprintf(ficgp,"\nunset title \n");
                   5665:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5666:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5667:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5668:    /*   } */
                   5669:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5670:    pstamp(ficresvij);
                   5671:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5672:    if(popbased==1)
                   5673:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5674:    else
                   5675:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5676:    fprintf(ficresvij,"# Age");
                   5677:    for(i=1; i<=nlstate;i++)
                   5678:      for(j=1; j<=nlstate;j++)
                   5679:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5680:    fprintf(ficresvij,"\n");
                   5681: 
                   5682:    xp=vector(1,npar);
                   5683:    dnewm=matrix(1,nlstate,1,npar);
                   5684:    doldm=matrix(1,nlstate,1,nlstate);
                   5685:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5686:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5687: 
                   5688:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5689:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5690:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5691:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5692:   
1.218     brouard  5693:    if(estepm < stepm){
                   5694:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5695:    }
                   5696:    else  hstepm=estepm;   
                   5697:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5698:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5699:       nhstepm is the number of hstepm from age to agelim 
                   5700:       nstepm is the number of stepm from age to agelim. 
                   5701:       Look at function hpijx to understand why because of memory size limitations, 
                   5702:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5703:       survival function given by stepm (the optimization length). Unfortunately it
                   5704:       means that if the survival funtion is printed every two years of age and if
                   5705:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5706:       results. So we changed our mind and took the option of the best precision.
                   5707:    */
                   5708:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5709:    agelim = AGESUP;
                   5710:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5711:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5712:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5713:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5714:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5715:      gp=matrix(0,nhstepm,1,nlstate);
                   5716:      gm=matrix(0,nhstepm,1,nlstate);
                   5717:                
                   5718:                
                   5719:      for(theta=1; theta <=npar; theta++){
                   5720:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5721:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5722:        }
                   5723:                        
1.242     brouard  5724:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5725:                        
                   5726:        if (popbased==1) {
                   5727:         if(mobilav ==0){
                   5728:           for(i=1; i<=nlstate;i++)
                   5729:             prlim[i][i]=probs[(int)age][i][ij];
                   5730:         }else{ /* mobilav */ 
                   5731:           for(i=1; i<=nlstate;i++)
                   5732:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5733:         }
                   5734:        }
                   5735:                        
1.235     brouard  5736:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5737:        for(j=1; j<= nlstate; j++){
                   5738:         for(h=0; h<=nhstepm; h++){
                   5739:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5740:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5741:         }
                   5742:        }
                   5743:        /* Next for computing probability of death (h=1 means
                   5744:          computed over hstepm matrices product = hstepm*stepm months) 
                   5745:          as a weighted average of prlim.
                   5746:        */
                   5747:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5748:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5749:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5750:        }    
                   5751:        /* end probability of death */
                   5752:                        
                   5753:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5754:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5755:                        
1.242     brouard  5756:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5757:                        
                   5758:        if (popbased==1) {
                   5759:         if(mobilav ==0){
                   5760:           for(i=1; i<=nlstate;i++)
                   5761:             prlim[i][i]=probs[(int)age][i][ij];
                   5762:         }else{ /* mobilav */ 
                   5763:           for(i=1; i<=nlstate;i++)
                   5764:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5765:         }
                   5766:        }
                   5767:                        
1.235     brouard  5768:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5769:                        
                   5770:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5771:         for(h=0; h<=nhstepm; h++){
                   5772:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5773:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5774:         }
                   5775:        }
                   5776:        /* This for computing probability of death (h=1 means
                   5777:          computed over hstepm matrices product = hstepm*stepm months) 
                   5778:          as a weighted average of prlim.
                   5779:        */
                   5780:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5781:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5782:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5783:        }    
                   5784:        /* end probability of death */
                   5785:                        
                   5786:        for(j=1; j<= nlstate; j++) /* vareij */
                   5787:         for(h=0; h<=nhstepm; h++){
                   5788:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5789:         }
                   5790:                        
                   5791:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5792:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5793:        }
                   5794:                        
                   5795:      } /* End theta */
                   5796:                
                   5797:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5798:                
                   5799:      for(h=0; h<=nhstepm; h++) /* veij */
                   5800:        for(j=1; j<=nlstate;j++)
                   5801:         for(theta=1; theta <=npar; theta++)
                   5802:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5803:                
                   5804:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5805:        for(theta=1; theta <=npar; theta++)
                   5806:         trgradgp[j][theta]=gradgp[theta][j];
                   5807:                
                   5808:                
                   5809:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5810:      for(i=1;i<=nlstate;i++)
                   5811:        for(j=1;j<=nlstate;j++)
                   5812:         vareij[i][j][(int)age] =0.;
                   5813:                
                   5814:      for(h=0;h<=nhstepm;h++){
                   5815:        for(k=0;k<=nhstepm;k++){
                   5816:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5817:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5818:         for(i=1;i<=nlstate;i++)
                   5819:           for(j=1;j<=nlstate;j++)
                   5820:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5821:        }
                   5822:      }
                   5823:                
                   5824:      /* pptj */
                   5825:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5826:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5827:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5828:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5829:         varppt[j][i]=doldmp[j][i];
                   5830:      /* end ppptj */
                   5831:      /*  x centered again */
                   5832:                
1.242     brouard  5833:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5834:                
                   5835:      if (popbased==1) {
                   5836:        if(mobilav ==0){
                   5837:         for(i=1; i<=nlstate;i++)
                   5838:           prlim[i][i]=probs[(int)age][i][ij];
                   5839:        }else{ /* mobilav */ 
                   5840:         for(i=1; i<=nlstate;i++)
                   5841:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   5842:        }
                   5843:      }
                   5844:                
                   5845:      /* This for computing probability of death (h=1 means
                   5846:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   5847:        as a weighted average of prlim.
                   5848:      */
1.235     brouard  5849:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  5850:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5851:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   5852:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   5853:      }    
                   5854:      /* end probability of death */
                   5855:                
                   5856:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   5857:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5858:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   5859:        for(i=1; i<=nlstate;i++){
                   5860:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   5861:        }
                   5862:      } 
                   5863:      fprintf(ficresprobmorprev,"\n");
                   5864:                
                   5865:      fprintf(ficresvij,"%.0f ",age );
                   5866:      for(i=1; i<=nlstate;i++)
                   5867:        for(j=1; j<=nlstate;j++){
                   5868:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   5869:        }
                   5870:      fprintf(ficresvij,"\n");
                   5871:      free_matrix(gp,0,nhstepm,1,nlstate);
                   5872:      free_matrix(gm,0,nhstepm,1,nlstate);
                   5873:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   5874:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   5875:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5876:    } /* End age */
                   5877:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   5878:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   5879:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   5880:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   5881:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   5882:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   5883:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   5884:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   5885:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5886:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   5887:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5888:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5889:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   5890:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   5891:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   5892:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   5893:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5894:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  5895:     */
1.218     brouard  5896:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   5897:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  5898: 
1.218     brouard  5899:    free_vector(xp,1,npar);
                   5900:    free_matrix(doldm,1,nlstate,1,nlstate);
                   5901:    free_matrix(dnewm,1,nlstate,1,npar);
                   5902:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5903:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   5904:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5905:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5906:    fclose(ficresprobmorprev);
                   5907:    fflush(ficgp);
                   5908:    fflush(fichtm); 
                   5909:  }  /* end varevsij */
1.126     brouard  5910: 
                   5911: /************ Variance of prevlim ******************/
1.235     brouard  5912:  void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  5913: {
1.205     brouard  5914:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  5915:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  5916: 
1.126     brouard  5917:   double **dnewm,**doldm;
                   5918:   int i, j, nhstepm, hstepm;
                   5919:   double *xp;
                   5920:   double *gp, *gm;
                   5921:   double **gradg, **trgradg;
1.208     brouard  5922:   double **mgm, **mgp;
1.126     brouard  5923:   double age,agelim;
                   5924:   int theta;
                   5925:   
                   5926:   pstamp(ficresvpl);
                   5927:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  5928:   fprintf(ficresvpl,"# Age ");
                   5929:   if(nresult >=1)
                   5930:     fprintf(ficresvpl," Result# ");
1.126     brouard  5931:   for(i=1; i<=nlstate;i++)
                   5932:       fprintf(ficresvpl," %1d-%1d",i,i);
                   5933:   fprintf(ficresvpl,"\n");
                   5934: 
                   5935:   xp=vector(1,npar);
                   5936:   dnewm=matrix(1,nlstate,1,npar);
                   5937:   doldm=matrix(1,nlstate,1,nlstate);
                   5938:   
                   5939:   hstepm=1*YEARM; /* Every year of age */
                   5940:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   5941:   agelim = AGESUP;
                   5942:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5943:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5944:     if (stepm >= YEARM) hstepm=1;
                   5945:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   5946:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  5947:     mgp=matrix(1,npar,1,nlstate);
                   5948:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  5949:     gp=vector(1,nlstate);
                   5950:     gm=vector(1,nlstate);
                   5951: 
                   5952:     for(theta=1; theta <=npar; theta++){
                   5953:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   5954:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5955:       }
1.209     brouard  5956:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5957:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5958:       else
1.235     brouard  5959:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5960:       for(i=1;i<=nlstate;i++){
1.126     brouard  5961:        gp[i] = prlim[i][i];
1.208     brouard  5962:        mgp[theta][i] = prlim[i][i];
                   5963:       }
1.126     brouard  5964:       for(i=1; i<=npar; i++) /* Computes gradient */
                   5965:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  5966:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5967:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5968:       else
1.235     brouard  5969:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5970:       for(i=1;i<=nlstate;i++){
1.126     brouard  5971:        gm[i] = prlim[i][i];
1.208     brouard  5972:        mgm[theta][i] = prlim[i][i];
                   5973:       }
1.126     brouard  5974:       for(i=1;i<=nlstate;i++)
                   5975:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  5976:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  5977:     } /* End theta */
                   5978: 
                   5979:     trgradg =matrix(1,nlstate,1,npar);
                   5980: 
                   5981:     for(j=1; j<=nlstate;j++)
                   5982:       for(theta=1; theta <=npar; theta++)
                   5983:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  5984:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5985:     /*   printf("\nmgm mgp %d ",(int)age); */
                   5986:     /*   for(j=1; j<=nlstate;j++){ */
                   5987:     /*         printf(" %d ",j); */
                   5988:     /*         for(theta=1; theta <=npar; theta++) */
                   5989:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   5990:     /*         printf("\n "); */
                   5991:     /*   } */
                   5992:     /* } */
                   5993:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5994:     /*   printf("\n gradg %d ",(int)age); */
                   5995:     /*   for(j=1; j<=nlstate;j++){ */
                   5996:     /*         printf("%d ",j); */
                   5997:     /*         for(theta=1; theta <=npar; theta++) */
                   5998:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   5999:     /*         printf("\n "); */
                   6000:     /*   } */
                   6001:     /* } */
1.126     brouard  6002: 
                   6003:     for(i=1;i<=nlstate;i++)
                   6004:       varpl[i][(int)age] =0.;
1.209     brouard  6005:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.205     brouard  6006:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6007:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
                   6008:     }else{
1.126     brouard  6009:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6010:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6011:     }
1.126     brouard  6012:     for(i=1;i<=nlstate;i++)
                   6013:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6014: 
                   6015:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6016:     if(nresult >=1)
                   6017:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6018:     for(i=1; i<=nlstate;i++)
                   6019:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6020:     fprintf(ficresvpl,"\n");
                   6021:     free_vector(gp,1,nlstate);
                   6022:     free_vector(gm,1,nlstate);
1.208     brouard  6023:     free_matrix(mgm,1,npar,1,nlstate);
                   6024:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6025:     free_matrix(gradg,1,npar,1,nlstate);
                   6026:     free_matrix(trgradg,1,nlstate,1,npar);
                   6027:   } /* End age */
                   6028: 
                   6029:   free_vector(xp,1,npar);
                   6030:   free_matrix(doldm,1,nlstate,1,npar);
                   6031:   free_matrix(dnewm,1,nlstate,1,nlstate);
                   6032: 
                   6033: }
                   6034: 
                   6035: /************ Variance of one-step probabilities  ******************/
                   6036: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6037:  {
                   6038:    int i, j=0,  k1, l1, tj;
                   6039:    int k2, l2, j1,  z1;
                   6040:    int k=0, l;
                   6041:    int first=1, first1, first2;
                   6042:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6043:    double **dnewm,**doldm;
                   6044:    double *xp;
                   6045:    double *gp, *gm;
                   6046:    double **gradg, **trgradg;
                   6047:    double **mu;
                   6048:    double age, cov[NCOVMAX+1];
                   6049:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6050:    int theta;
                   6051:    char fileresprob[FILENAMELENGTH];
                   6052:    char fileresprobcov[FILENAMELENGTH];
                   6053:    char fileresprobcor[FILENAMELENGTH];
                   6054:    double ***varpij;
                   6055: 
                   6056:    strcpy(fileresprob,"PROB_"); 
                   6057:    strcat(fileresprob,fileres);
                   6058:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6059:      printf("Problem with resultfile: %s\n", fileresprob);
                   6060:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6061:    }
                   6062:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6063:    strcat(fileresprobcov,fileresu);
                   6064:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6065:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6066:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6067:    }
                   6068:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6069:    strcat(fileresprobcor,fileresu);
                   6070:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6071:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6072:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6073:    }
                   6074:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6075:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6076:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6077:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6078:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6079:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6080:    pstamp(ficresprob);
                   6081:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6082:    fprintf(ficresprob,"# Age");
                   6083:    pstamp(ficresprobcov);
                   6084:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6085:    fprintf(ficresprobcov,"# Age");
                   6086:    pstamp(ficresprobcor);
                   6087:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6088:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6089: 
                   6090: 
1.222     brouard  6091:    for(i=1; i<=nlstate;i++)
                   6092:      for(j=1; j<=(nlstate+ndeath);j++){
                   6093:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6094:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6095:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6096:      }  
                   6097:    /* fprintf(ficresprob,"\n");
                   6098:       fprintf(ficresprobcov,"\n");
                   6099:       fprintf(ficresprobcor,"\n");
                   6100:    */
                   6101:    xp=vector(1,npar);
                   6102:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6103:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6104:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6105:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6106:    first=1;
                   6107:    fprintf(ficgp,"\n# Routine varprob");
                   6108:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6109:    fprintf(fichtm,"\n");
                   6110: 
                   6111:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.</li>\n",optionfilehtmcov);
                   6112:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6113:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6114: and drawn. It helps understanding how is the covariance between two incidences.\
                   6115:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6116:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6117: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6118: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6119: standard deviations wide on each axis. <br>\
                   6120:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6121:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6122: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6123: 
1.222     brouard  6124:    cov[1]=1;
                   6125:    /* tj=cptcoveff; */
1.225     brouard  6126:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6127:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6128:    j1=0;
1.224     brouard  6129:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6130:      if  (cptcovn>0) {
                   6131:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6132:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6133:        fprintf(ficresprob, "**********\n#\n");
                   6134:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6135:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6136:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6137:                        
1.222     brouard  6138:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6139:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6140:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6141:                        
                   6142:                        
1.222     brouard  6143:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6144:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6145:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6146:                        
1.222     brouard  6147:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6148:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6149:        fprintf(ficresprobcor, "**********\n#");    
                   6150:        if(invalidvarcomb[j1]){
                   6151:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6152:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6153:         continue;
                   6154:        }
                   6155:      }
                   6156:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6157:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6158:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6159:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6160:      for (age=bage; age<=fage; age ++){ 
                   6161:        cov[2]=age;
                   6162:        if(nagesqr==1)
                   6163:         cov[3]= age*age;
                   6164:        for (k=1; k<=cptcovn;k++) {
                   6165:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6166:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6167:                                                                    * 1  1 1 1 1
                   6168:                                                                    * 2  2 1 1 1
                   6169:                                                                    * 3  1 2 1 1
                   6170:                                                                    */
                   6171:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6172:        }
                   6173:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6174:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6175:        for (k=1; k<=cptcovprod;k++)
                   6176:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6177:                        
                   6178:                        
1.222     brouard  6179:        for(theta=1; theta <=npar; theta++){
                   6180:         for(i=1; i<=npar; i++)
                   6181:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6182:                                
1.222     brouard  6183:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6184:                                
1.222     brouard  6185:         k=0;
                   6186:         for(i=1; i<= (nlstate); i++){
                   6187:           for(j=1; j<=(nlstate+ndeath);j++){
                   6188:             k=k+1;
                   6189:             gp[k]=pmmij[i][j];
                   6190:           }
                   6191:         }
1.220     brouard  6192:                                
1.222     brouard  6193:         for(i=1; i<=npar; i++)
                   6194:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6195:                                
1.222     brouard  6196:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6197:         k=0;
                   6198:         for(i=1; i<=(nlstate); i++){
                   6199:           for(j=1; j<=(nlstate+ndeath);j++){
                   6200:             k=k+1;
                   6201:             gm[k]=pmmij[i][j];
                   6202:           }
                   6203:         }
1.220     brouard  6204:                                
1.222     brouard  6205:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6206:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6207:        }
1.126     brouard  6208: 
1.222     brouard  6209:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6210:         for(theta=1; theta <=npar; theta++)
                   6211:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6212:                        
1.222     brouard  6213:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6214:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6215:                        
1.222     brouard  6216:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6217:                        
1.222     brouard  6218:        k=0;
                   6219:        for(i=1; i<=(nlstate); i++){
                   6220:         for(j=1; j<=(nlstate+ndeath);j++){
                   6221:           k=k+1;
                   6222:           mu[k][(int) age]=pmmij[i][j];
                   6223:         }
                   6224:        }
                   6225:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6226:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6227:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6228:                        
1.222     brouard  6229:        /*printf("\n%d ",(int)age);
                   6230:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6231:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6232:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6233:         }*/
1.220     brouard  6234:                        
1.222     brouard  6235:        fprintf(ficresprob,"\n%d ",(int)age);
                   6236:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6237:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6238:                        
1.222     brouard  6239:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6240:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6241:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6242:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6243:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6244:        }
                   6245:        i=0;
                   6246:        for (k=1; k<=(nlstate);k++){
                   6247:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6248:           i++;
                   6249:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6250:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6251:           for (j=1; j<=i;j++){
                   6252:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6253:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6254:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6255:           }
                   6256:         }
                   6257:        }/* end of loop for state */
                   6258:      } /* end of loop for age */
                   6259:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6260:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6261:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6262:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6263:     
                   6264:      /* Confidence intervalle of pij  */
                   6265:      /*
                   6266:        fprintf(ficgp,"\nunset parametric;unset label");
                   6267:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6268:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6269:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6270:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6271:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6272:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6273:      */
                   6274:                
                   6275:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6276:      first1=1;first2=2;
                   6277:      for (k2=1; k2<=(nlstate);k2++){
                   6278:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6279:         if(l2==k2) continue;
                   6280:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6281:         for (k1=1; k1<=(nlstate);k1++){
                   6282:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6283:             if(l1==k1) continue;
                   6284:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6285:             if(i<=j) continue;
                   6286:             for (age=bage; age<=fage; age ++){ 
                   6287:               if ((int)age %5==0){
                   6288:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6289:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6290:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6291:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6292:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6293:                 c12=cv12/sqrt(v1*v2);
                   6294:                 /* Computing eigen value of matrix of covariance */
                   6295:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6296:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6297:                 if ((lc2 <0) || (lc1 <0) ){
                   6298:                   if(first2==1){
                   6299:                     first1=0;
                   6300:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6301:                   }
                   6302:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6303:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6304:                   /* lc2=fabs(lc2); */
                   6305:                 }
1.220     brouard  6306:                                                                
1.222     brouard  6307:                 /* Eigen vectors */
                   6308:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   6309:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6310:                 v21=(lc1-v1)/cv12*v11;
                   6311:                 v12=-v21;
                   6312:                 v22=v11;
                   6313:                 tnalp=v21/v11;
                   6314:                 if(first1==1){
                   6315:                   first1=0;
                   6316:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6317:                 }
                   6318:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6319:                 /*printf(fignu*/
                   6320:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6321:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6322:                 if(first==1){
                   6323:                   first=0;
                   6324:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6325:                   fprintf(ficgp,"\nset parametric;unset label");
                   6326:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6327:                   fprintf(ficgp,"\nset ter svg size 640, 480");
                   6328:                   fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6329:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6330: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6331:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6332:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6333:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6334:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6335:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6336:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6337:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6338:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
                   6339:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                                                         \
                   6340:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6341:                 }else{
                   6342:                   first=0;
                   6343:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6344:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6345:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6346:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
                   6347:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                 \
                   6348:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6349:                 }/* if first */
                   6350:               } /* age mod 5 */
                   6351:             } /* end loop age */
                   6352:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6353:             first=1;
                   6354:           } /*l12 */
                   6355:         } /* k12 */
                   6356:        } /*l1 */
                   6357:      }/* k1 */
                   6358:    }  /* loop on combination of covariates j1 */
                   6359:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6360:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6361:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6362:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6363:    free_vector(xp,1,npar);
                   6364:    fclose(ficresprob);
                   6365:    fclose(ficresprobcov);
                   6366:    fclose(ficresprobcor);
                   6367:    fflush(ficgp);
                   6368:    fflush(fichtmcov);
                   6369:  }
1.126     brouard  6370: 
                   6371: 
                   6372: /******************* Printing html file ***********/
1.201     brouard  6373: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6374:                  int lastpass, int stepm, int weightopt, char model[],\
                   6375:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.217     brouard  6376:                  int popforecast, int prevfcast, int backcast, int estepm , \
1.213     brouard  6377:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   6378:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.237     brouard  6379:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6380: 
                   6381:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6382:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6383: </ul>");
1.237     brouard  6384:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6385: </ul>", model);
1.214     brouard  6386:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6387:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6388:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6389:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6390:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6391:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6392:    fprintf(fichtm,"\
                   6393:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6394:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6395:    fprintf(fichtm,"\
1.217     brouard  6396:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6397:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6398:    fprintf(fichtm,"\
1.126     brouard  6399:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6400:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6401:    fprintf(fichtm,"\
1.217     brouard  6402:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6403:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6404:    fprintf(fichtm,"\
1.211     brouard  6405:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6406:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6407:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6408:    if(prevfcast==1){
                   6409:      fprintf(fichtm,"\
                   6410:  - Prevalence projections by age and states:                           \
1.201     brouard  6411:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6412:    }
1.126     brouard  6413: 
1.222     brouard  6414:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
1.126     brouard  6415: 
1.225     brouard  6416:    m=pow(2,cptcoveff);
1.222     brouard  6417:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6418: 
1.222     brouard  6419:    jj1=0;
1.237     brouard  6420: 
                   6421:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6422:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6423:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6424:        continue;
1.220     brouard  6425: 
1.222     brouard  6426:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6427:      jj1++;
                   6428:      if (cptcovn > 0) {
                   6429:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6430:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6431:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6432:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6433:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6434:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6435:        }
1.237     brouard  6436:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6437:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6438:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6439:       }
                   6440:        
1.230     brouard  6441:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6442:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6443:        if(invalidvarcomb[k1]){
                   6444:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6445:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6446:         continue;
                   6447:        }
                   6448:      }
                   6449:      /* aij, bij */
1.241     brouard  6450:      fprintf(fichtm,"<br>- Logit model (yours is: 1+age+%s), for example: logit(pij)=log(pij/pii)= aij+ bij age + V1 age + etc. as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
                   6451: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6452:      /* Pij */
1.241     brouard  6453:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6454: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6455:      /* Quasi-incidences */
                   6456:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6457:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6458:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6459: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6460: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6461:      /* Survival functions (period) in state j */
                   6462:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6463:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6464: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6465:      }
                   6466:      /* State specific survival functions (period) */
                   6467:      for(cpt=1; cpt<=nlstate;cpt++){
                   6468:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6469:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.241     brouard  6470:  <a href=\"%s_%d-%d-%d.svg\">%s_%d%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6471:      }
                   6472:      /* Period (stable) prevalence in each health state */
                   6473:      for(cpt=1; cpt<=nlstate;cpt++){
1.255     brouard  6474:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d some years earlier, knowing that we will be in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6475: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6476:      }
                   6477:      if(backcast==1){
                   6478:        /* Period (stable) back prevalence in each health state */
                   6479:        for(cpt=1; cpt<=nlstate;cpt++){
1.255     brouard  6480:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability to be in state %d at a younger age, knowing that we will be in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6481: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6482:        }
1.217     brouard  6483:      }
1.222     brouard  6484:      if(prevfcast==1){
                   6485:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6486:        for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6487:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f) up to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6488: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6489:        }
                   6490:      }
1.220     brouard  6491:         
1.222     brouard  6492:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6493:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6494: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6495:      }
                   6496:      /* } /\* end i1 *\/ */
                   6497:    }/* End k1 */
                   6498:    fprintf(fichtm,"</ul>");
1.126     brouard  6499: 
1.222     brouard  6500:    fprintf(fichtm,"\
1.126     brouard  6501: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6502:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6503:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6504: But because parameters are usually highly correlated (a higher incidence of disability \
                   6505: and a higher incidence of recovery can give very close observed transition) it might \
                   6506: be very useful to look not only at linear confidence intervals estimated from the \
                   6507: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6508: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6509: covariance matrix of the one-step probabilities. \
                   6510: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6511: 
1.222     brouard  6512:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6513:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6514:    fprintf(fichtm,"\
1.126     brouard  6515:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6516:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6517: 
1.222     brouard  6518:    fprintf(fichtm,"\
1.126     brouard  6519:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6520:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6521:    fprintf(fichtm,"\
1.126     brouard  6522:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6523:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6524:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6525:    fprintf(fichtm,"\
1.126     brouard  6526:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6527:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6528:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6529:    fprintf(fichtm,"\
1.128     brouard  6530:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6531:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6532:    fprintf(fichtm,"\
1.128     brouard  6533:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6534:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6535:    fprintf(fichtm,"\
1.126     brouard  6536:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6537:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6538: 
                   6539: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6540: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6541: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6542: /*     <br>",fileres,fileres,fileres,fileres); */
                   6543: /*  else  */
                   6544: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6545:    fflush(fichtm);
                   6546:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6547: 
1.225     brouard  6548:    m=pow(2,cptcoveff);
1.222     brouard  6549:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6550: 
1.222     brouard  6551:    jj1=0;
1.237     brouard  6552: 
1.241     brouard  6553:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6554:    for(k1=1; k1<=m;k1++){
1.253     brouard  6555:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6556:        continue;
1.222     brouard  6557:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6558:      jj1++;
1.126     brouard  6559:      if (cptcovn > 0) {
                   6560:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6561:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6562:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6563:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6564:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6565:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6566:       }
                   6567: 
1.126     brouard  6568:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6569: 
1.222     brouard  6570:        if(invalidvarcomb[k1]){
                   6571:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6572:         continue;
                   6573:        }
1.126     brouard  6574:      }
                   6575:      for(cpt=1; cpt<=nlstate;cpt++) {
1.218     brouard  6576:        fprintf(fichtm,"\n<br>- Observed (cross-sectional) and period (incidence based) \
1.241     brouard  6577: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
                   6578: <img src=\"%s_%d-%d-%d.svg\">",cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  6579:      }
                   6580:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6581: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6582: true period expectancies (those weighted with period prevalences are also\
                   6583:  drawn in addition to the population based expectancies computed using\
1.241     brouard  6584:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   6585: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  6586:      /* } /\* end i1 *\/ */
                   6587:    }/* End k1 */
1.241     brouard  6588:   }/* End nres */
1.222     brouard  6589:    fprintf(fichtm,"</ul>");
                   6590:    fflush(fichtm);
1.126     brouard  6591: }
                   6592: 
                   6593: /******************* Gnuplot file **************/
1.223     brouard  6594: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[]){
1.126     brouard  6595: 
                   6596:   char dirfileres[132],optfileres[132];
1.223     brouard  6597:   char gplotcondition[132];
1.237     brouard  6598:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6599:   int lv=0, vlv=0, kl=0;
1.130     brouard  6600:   int ng=0;
1.201     brouard  6601:   int vpopbased;
1.223     brouard  6602:   int ioffset; /* variable offset for columns */
1.235     brouard  6603:   int nres=0; /* Index of resultline */
1.219     brouard  6604: 
1.126     brouard  6605: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6606: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6607: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6608: /*   } */
                   6609: 
                   6610:   /*#ifdef windows */
                   6611:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6612:   /*#endif */
1.225     brouard  6613:   m=pow(2,cptcoveff);
1.126     brouard  6614: 
1.202     brouard  6615:   /* Contribution to likelihood */
                   6616:   /* Plot the probability implied in the likelihood */
1.223     brouard  6617:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6618:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6619:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6620:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6621: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6622:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6623: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6624:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6625:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6626:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6627:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6628:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6629:   for (i=1; i<= nlstate ; i ++) {
                   6630:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6631:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6632:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6633:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6634:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6635:     }
                   6636:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6637:   }
                   6638:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6639:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6640:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6641:   fprintf(ficgp,"\nset out;unset log\n");
                   6642:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6643: 
1.126     brouard  6644:   strcpy(dirfileres,optionfilefiname);
                   6645:   strcpy(optfileres,"vpl");
1.223     brouard  6646:   /* 1eme*/
1.238     brouard  6647:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   6648:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  6649:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  6650:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  6651:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6652:          continue;
                   6653:        /* We are interested in selected combination by the resultline */
1.246     brouard  6654:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  6655:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
                   6656:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6657:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   6658:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6659:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6660:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6661:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   6662:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  6663:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  6664:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6665:        }
                   6666:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  6667:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  6668:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6669:        }       
1.246     brouard  6670:        /* printf("\n#\n"); */
1.238     brouard  6671:        fprintf(ficgp,"\n#\n");
                   6672:        if(invalidvarcomb[k1]){
                   6673:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6674:          continue;
                   6675:        }
1.235     brouard  6676:       
1.241     brouard  6677:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   6678:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
                   6679:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres);
1.235     brouard  6680:       
1.238     brouard  6681:        for (i=1; i<= nlstate ; i ++) {
                   6682:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6683:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   6684:        }
1.242     brouard  6685:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres);
1.238     brouard  6686:        for (i=1; i<= nlstate ; i ++) {
                   6687:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6688:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6689:        } 
1.242     brouard  6690:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); 
1.238     brouard  6691:        for (i=1; i<= nlstate ; i ++) {
                   6692:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6693:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6694:        }  
                   6695:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1));
                   6696:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   6697:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  6698:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  6699:          if(cptcoveff ==0){
1.245     brouard  6700:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  6701:          }else{
                   6702:            kl=0;
                   6703:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   6704:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6705:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6706:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6707:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6708:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  6709:              kl++;
1.238     brouard  6710:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6711:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6712:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6713:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6714:              if(k==cptcoveff){
1.245     brouard  6715:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  6716:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  6717:              }else{
                   6718:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   6719:                kl++;
                   6720:              }
                   6721:            } /* end covariate */
                   6722:          } /* end if no covariate */
                   6723:        } /* end if backcast */
                   6724:        fprintf(ficgp,"\nset out \n");
                   6725:       } /* nres */
1.201     brouard  6726:     } /* k1 */
                   6727:   } /* cpt */
1.235     brouard  6728: 
                   6729:   
1.126     brouard  6730:   /*2 eme*/
1.238     brouard  6731:   for (k1=1; k1<= m ; k1 ++){  
                   6732:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6733:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6734:        continue;
                   6735:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
                   6736:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  6737:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6738:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6739:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6740:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6741:        vlv= nbcode[Tvaraff[k]][lv];
                   6742:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6743:       }
1.237     brouard  6744:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  6745:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  6746:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  6747:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  6748:       }
1.211     brouard  6749:       fprintf(ficgp,"\n#\n");
1.223     brouard  6750:       if(invalidvarcomb[k1]){
                   6751:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6752:        continue;
                   6753:       }
1.219     brouard  6754:                        
1.241     brouard  6755:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  6756:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
                   6757:        if(vpopbased==0)
                   6758:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
                   6759:        else
                   6760:          fprintf(ficgp,"\nreplot ");
                   6761:        for (i=1; i<= nlstate+1 ; i ++) {
                   6762:          k=2*i;
                   6763:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1, vpopbased);
                   6764:          for (j=1; j<= nlstate+1 ; j ++) {
                   6765:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6766:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6767:          }   
                   6768:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   6769:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
                   6770:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6771:          for (j=1; j<= nlstate+1 ; j ++) {
                   6772:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6773:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6774:          }   
                   6775:          fprintf(ficgp,"\" t\"\" w l lt 0,");
                   6776:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6777:          for (j=1; j<= nlstate+1 ; j ++) {
                   6778:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6779:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6780:          }   
                   6781:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   6782:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   6783:        } /* state */
                   6784:       } /* vpopbased */
1.244     brouard  6785:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  6786:     } /* end nres */
                   6787:   } /* k1 end 2 eme*/
                   6788:        
                   6789:        
                   6790:   /*3eme*/
                   6791:   for (k1=1; k1<= m ; k1 ++){
                   6792:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6793:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6794:        continue;
                   6795: 
                   6796:       for (cpt=1; cpt<= nlstate ; cpt ++) {
                   6797:        fprintf(ficgp,"\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
                   6798:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6799:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6800:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6801:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6802:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6803:          vlv= nbcode[Tvaraff[k]][lv];
                   6804:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6805:        }
                   6806:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6807:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6808:        }       
                   6809:        fprintf(ficgp,"\n#\n");
                   6810:        if(invalidvarcomb[k1]){
                   6811:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6812:          continue;
                   6813:        }
                   6814:                        
                   6815:        /*       k=2+nlstate*(2*cpt-2); */
                   6816:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  6817:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.238     brouard  6818:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.201     brouard  6819: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),k1-1,k1-1,k,cpt);
1.238     brouard  6820:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6821:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6822:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   6823:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6824:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6825:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  6826:                                
1.238     brouard  6827:        */
                   6828:        for (i=1; i< nlstate ; i ++) {
                   6829:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+i,cpt,i+1);
                   6830:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  6831:                                
1.238     brouard  6832:        } 
                   6833:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+nlstate,cpt);
                   6834:       }
                   6835:     } /* end nres */
                   6836:   } /* end kl 3eme */
1.126     brouard  6837:   
1.223     brouard  6838:   /* 4eme */
1.201     brouard  6839:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  6840:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   6841:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6842:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  6843:        continue;
1.238     brouard  6844:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
                   6845:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   6846:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6847:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6848:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6849:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6850:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6851:          vlv= nbcode[Tvaraff[k]][lv];
                   6852:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6853:        }
                   6854:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6855:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6856:        }       
                   6857:        fprintf(ficgp,"\n#\n");
                   6858:        if(invalidvarcomb[k1]){
                   6859:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6860:          continue;
1.223     brouard  6861:        }
1.238     brouard  6862:       
1.241     brouard  6863:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.238     brouard  6864:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6865: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6866:        k=3;
                   6867:        for (i=1; i<= nlstate ; i ++){
                   6868:          if(i==1){
                   6869:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6870:          }else{
                   6871:            fprintf(ficgp,", '' ");
                   6872:          }
                   6873:          l=(nlstate+ndeath)*(i-1)+1;
                   6874:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6875:          for (j=2; j<= nlstate+ndeath ; j ++)
                   6876:            fprintf(ficgp,"+$%d",k+l+j-1);
                   6877:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   6878:        } /* nlstate */
                   6879:        fprintf(ficgp,"\nset out\n");
                   6880:       } /* end cpt state*/ 
                   6881:     } /* end nres */
                   6882:   } /* end covariate k1 */  
                   6883: 
1.220     brouard  6884: /* 5eme */
1.201     brouard  6885:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  6886:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   6887:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6888:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  6889:        continue;
1.238     brouard  6890:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
                   6891:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   6892:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6893:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6894:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6895:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6896:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6897:          vlv= nbcode[Tvaraff[k]][lv];
                   6898:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6899:        }
                   6900:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6901:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6902:        }       
                   6903:        fprintf(ficgp,"\n#\n");
                   6904:        if(invalidvarcomb[k1]){
                   6905:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6906:          continue;
                   6907:        }
1.227     brouard  6908:       
1.241     brouard  6909:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.238     brouard  6910:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6911: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6912:        k=3;
                   6913:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6914:          if(j==1)
                   6915:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6916:          else
                   6917:            fprintf(ficgp,", '' ");
                   6918:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6919:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   6920:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   6921:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   6922:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   6923:        } /* nlstate */
                   6924:        fprintf(ficgp,", '' ");
                   6925:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   6926:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6927:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6928:          if(j < nlstate)
                   6929:            fprintf(ficgp,"$%d +",k+l);
                   6930:          else
                   6931:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   6932:        }
                   6933:        fprintf(ficgp,"\nset out\n");
                   6934:       } /* end cpt state*/ 
                   6935:     } /* end covariate */  
                   6936:   } /* end nres */
1.227     brouard  6937:   
1.220     brouard  6938: /* 6eme */
1.202     brouard  6939:   /* CV preval stable (period) for each covariate */
1.237     brouard  6940:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6941:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6942:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6943:       continue;
1.255     brouard  6944:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.227     brouard  6945:       
1.211     brouard  6946:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  6947:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  6948:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6949:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6950:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6951:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6952:        vlv= nbcode[Tvaraff[k]][lv];
                   6953:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6954:       }
1.237     brouard  6955:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6956:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6957:       }        
1.211     brouard  6958:       fprintf(ficgp,"\n#\n");
1.223     brouard  6959:       if(invalidvarcomb[k1]){
1.227     brouard  6960:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6961:        continue;
1.223     brouard  6962:       }
1.227     brouard  6963:       
1.241     brouard  6964:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.126     brouard  6965:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  6966: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6967:       k=3; /* Offset */
1.255     brouard  6968:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  6969:        if(i==1)
                   6970:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6971:        else
                   6972:          fprintf(ficgp,", '' ");
1.255     brouard  6973:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  6974:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6975:        for (j=2; j<= nlstate ; j ++)
                   6976:          fprintf(ficgp,"+$%d",k+l+j-1);
                   6977:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  6978:       } /* nlstate */
1.201     brouard  6979:       fprintf(ficgp,"\nset out\n");
1.153     brouard  6980:     } /* end cpt state*/ 
                   6981:   } /* end covariate */  
1.227     brouard  6982:   
                   6983:   
1.220     brouard  6984: /* 7eme */
1.218     brouard  6985:   if(backcast == 1){
1.217     brouard  6986:     /* CV back preval stable (period) for each covariate */
1.237     brouard  6987:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6988:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6989:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6990:        continue;
1.255     brouard  6991:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life ending state */
                   6992:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  6993:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6994:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6995:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6996:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  6997:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  6998:          vlv= nbcode[Tvaraff[k]][lv];
                   6999:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7000:        }
1.237     brouard  7001:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7002:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7003:        }       
1.227     brouard  7004:        fprintf(ficgp,"\n#\n");
                   7005:        if(invalidvarcomb[k1]){
                   7006:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7007:          continue;
                   7008:        }
                   7009:        
1.241     brouard  7010:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.227     brouard  7011:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7012: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7013:        k=3; /* Offset */
1.255     brouard  7014:        for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7015:          if(i==1)
                   7016:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7017:          else
                   7018:            fprintf(ficgp,", '' ");
                   7019:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7020:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7021:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7022:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7023:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7024:          /* for (j=2; j<= nlstate ; j ++) */
                   7025:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7026:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
                   7027:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",i,cpt);
                   7028:        } /* nlstate */
                   7029:        fprintf(ficgp,"\nset out\n");
1.218     brouard  7030:       } /* end cpt state*/ 
                   7031:     } /* end covariate */  
                   7032:   } /* End if backcast */
                   7033:   
1.223     brouard  7034:   /* 8eme */
1.218     brouard  7035:   if(prevfcast==1){
                   7036:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7037:     
1.237     brouard  7038:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7039:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7040:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7041:        continue;
1.211     brouard  7042:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  7043:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7044:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7045:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7046:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7047:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7048:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7049:          vlv= nbcode[Tvaraff[k]][lv];
                   7050:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7051:        }
1.237     brouard  7052:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7053:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7054:        }       
1.227     brouard  7055:        fprintf(ficgp,"\n#\n");
                   7056:        if(invalidvarcomb[k1]){
                   7057:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7058:          continue;
                   7059:        }
                   7060:        
                   7061:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7062:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.227     brouard  7063:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7064: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7065:        for (i=1; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7066:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7067:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7068:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7069:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7070:          if(i==1){
                   7071:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7072:          }else{
                   7073:            fprintf(ficgp,",\\\n '' ");
                   7074:          }
                   7075:          if(cptcoveff ==0){ /* No covariate */
                   7076:            ioffset=2; /* Age is in 2 */
                   7077:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7078:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7079:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7080:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7081:            fprintf(ficgp," u %d:(", ioffset); 
                   7082:            if(i==nlstate+1)
                   7083:              fprintf(ficgp," $%d/(1.-$%d)) t 'pw.%d' with line ",      \
                   7084:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7085:            else
                   7086:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7087:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7088:          }else{ /* more than 2 covariates */
                   7089:            if(cptcoveff ==1){
                   7090:              ioffset=4; /* Age is in 4 */
                   7091:            }else{
                   7092:              ioffset=6; /* Age is in 6 */
                   7093:              /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7094:              /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7095:            }   
                   7096:            fprintf(ficgp," u %d:(",ioffset); 
                   7097:            kl=0;
                   7098:            strcpy(gplotcondition,"(");
                   7099:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7100:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7101:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7102:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7103:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7104:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7105:              kl++;
                   7106:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7107:              kl++;
                   7108:              if(k <cptcoveff && cptcoveff>1)
                   7109:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7110:            }
                   7111:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7112:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7113:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7114:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7115:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7116:            if(i==nlstate+1){
                   7117:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p.%d' with line ", gplotcondition, \
                   7118:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7119:            }else{
                   7120:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7121:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7122:            }
                   7123:          } /* end if covariate */
                   7124:        } /* nlstate */
                   7125:        fprintf(ficgp,"\nset out\n");
1.223     brouard  7126:       } /* end cpt state*/
                   7127:     } /* end covariate */
                   7128:   } /* End if prevfcast */
1.227     brouard  7129:   
                   7130:   
1.238     brouard  7131:   /* 9eme writing MLE parameters */
                   7132:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7133:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7134:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7135:     for(k=1; k <=(nlstate+ndeath); k++){
                   7136:       if (k != i) {
1.227     brouard  7137:        fprintf(ficgp,"#   current state %d\n",k);
                   7138:        for(j=1; j <=ncovmodel; j++){
                   7139:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7140:          jk++; 
                   7141:        }
                   7142:        fprintf(ficgp,"\n");
1.126     brouard  7143:       }
                   7144:     }
1.223     brouard  7145:   }
1.187     brouard  7146:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7147:   
1.145     brouard  7148:   /*goto avoid;*/
1.238     brouard  7149:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7150:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7151:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7152:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7153:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7154:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7155:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7156:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7157:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7158:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7159:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7160:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7161:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7162:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7163:   fprintf(ficgp,"#\n");
1.223     brouard  7164:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7165:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7166:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7167:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.237     brouard  7168:     fprintf(ficgp,"#   jk=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7169:     for(jk=1; jk <=m; jk++)  /* For each combination of covariate */
                   7170:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7171:       if(m != 1 && TKresult[nres]!= jk)
1.237     brouard  7172:        continue;
                   7173:       fprintf(ficgp,"# Combination of dummy  jk=%d and ",jk);
                   7174:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7175:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7176:       }        
                   7177:       fprintf(ficgp,"\n#\n");
1.241     brouard  7178:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng,nres);
1.223     brouard  7179:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7180:       if (ng==1){
                   7181:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7182:        fprintf(ficgp,"\nunset log y");
                   7183:       }else if (ng==2){
                   7184:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7185:        fprintf(ficgp,"\nset log y");
                   7186:       }else if (ng==3){
                   7187:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7188:        fprintf(ficgp,"\nset log y");
                   7189:       }else
                   7190:        fprintf(ficgp,"\nunset title ");
                   7191:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7192:       i=1;
                   7193:       for(k2=1; k2<=nlstate; k2++) {
                   7194:        k3=i;
                   7195:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7196:          if (k != k2){
                   7197:            switch( ng) {
                   7198:            case 1:
                   7199:              if(nagesqr==0)
                   7200:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7201:              else /* nagesqr =1 */
                   7202:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7203:              break;
                   7204:            case 2: /* ng=2 */
                   7205:              if(nagesqr==0)
                   7206:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7207:              else /* nagesqr =1 */
                   7208:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7209:              break;
                   7210:            case 3:
                   7211:              if(nagesqr==0)
                   7212:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7213:              else /* nagesqr =1 */
                   7214:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7215:              break;
                   7216:            }
                   7217:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7218:            ijp=1; /* product no age */
                   7219:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7220:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7221:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.237     brouard  7222:              if(j==Tage[ij]) { /* Product by age */
                   7223:                if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
1.238     brouard  7224:                  if(DummyV[j]==0){
1.237     brouard  7225:                    fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7226:                  }else{ /* quantitative */
                   7227:                    fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7228:                    /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7229:                  }
                   7230:                  ij++;
                   7231:                }
                   7232:              }else if(j==Tprod[ijp]) { /* */ 
                   7233:                /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7234:                if(ijp <=cptcovprod) { /* Product */
1.238     brouard  7235:                  if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7236:                    if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
1.237     brouard  7237:                      /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],nbcode[Tvard[ijp][2]][codtabm(jk,j)]); */
                   7238:                      fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7239:                    }else{ /* Vn is dummy and Vm is quanti */
                   7240:                      /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7241:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7242:                    }
                   7243:                  }else{ /* Vn*Vm Vn is quanti */
1.238     brouard  7244:                    if(DummyV[Tvard[ijp][2]]==0){
1.237     brouard  7245:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7246:                    }else{ /* Both quanti */
                   7247:                      fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7248:                    }
                   7249:                  }
1.238     brouard  7250:                  ijp++;
1.237     brouard  7251:                }
                   7252:              } else{  /* simple covariate */
                   7253:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(jk,j)]); /\* Valgrind bug nbcode *\/ */
                   7254:                if(Dummy[j]==0){
                   7255:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7256:                }else{ /* quantitative */
                   7257:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.223     brouard  7258:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7259:                }
1.237     brouard  7260:              } /* end simple */
                   7261:            } /* end j */
1.223     brouard  7262:          }else{
                   7263:            i=i-ncovmodel;
                   7264:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7265:              fprintf(ficgp," (1.");
                   7266:          }
1.227     brouard  7267:          
1.223     brouard  7268:          if(ng != 1){
                   7269:            fprintf(ficgp,")/(1");
1.227     brouard  7270:            
1.223     brouard  7271:            for(k1=1; k1 <=nlstate; k1++){ 
                   7272:              if(nagesqr==0)
                   7273:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                   7274:              else /* nagesqr =1 */
                   7275:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1,k3+(k1-1)*ncovmodel+1+nagesqr);
1.217     brouard  7276:               
1.223     brouard  7277:              ij=1;
                   7278:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.237     brouard  7279:                if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7280:                  if(ij <=cptcovage) { /* Bug valgrind */
1.223     brouard  7281:                    fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                   7282:                    /* fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7283:                    ij++;
                   7284:                  }
                   7285:                }
                   7286:                else
1.225     brouard  7287:                  fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7288:              }
                   7289:              fprintf(ficgp,")");
                   7290:            }
                   7291:            fprintf(ficgp,")");
                   7292:            if(ng ==2)
                   7293:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   7294:            else /* ng= 3 */
                   7295:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   7296:          }else{ /* end ng <> 1 */
                   7297:            if( k !=k2) /* logit p11 is hard to draw */
                   7298:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   7299:          }
                   7300:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7301:            fprintf(ficgp,",");
                   7302:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7303:            fprintf(ficgp,",");
                   7304:          i=i+ncovmodel;
                   7305:        } /* end k */
                   7306:       } /* end k2 */
                   7307:       fprintf(ficgp,"\n set out\n");
                   7308:     } /* end jk */
                   7309:   } /* end ng */
                   7310:   /* avoid: */
                   7311:   fflush(ficgp); 
1.126     brouard  7312: }  /* end gnuplot */
                   7313: 
                   7314: 
                   7315: /*************** Moving average **************/
1.219     brouard  7316: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  7317:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  7318:    
1.222     brouard  7319:    int i, cpt, cptcod;
                   7320:    int modcovmax =1;
                   7321:    int mobilavrange, mob;
                   7322:    int iage=0;
                   7323: 
                   7324:    double sum=0.;
                   7325:    double age;
                   7326:    double *sumnewp, *sumnewm;
                   7327:    double *agemingood, *agemaxgood; /* Currently identical for all covariates */
                   7328:   
                   7329:   
1.225     brouard  7330:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  7331:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   7332: 
                   7333:    sumnewp = vector(1,ncovcombmax);
                   7334:    sumnewm = vector(1,ncovcombmax);
                   7335:    agemingood = vector(1,ncovcombmax); 
                   7336:    agemaxgood = vector(1,ncovcombmax);
                   7337: 
                   7338:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7339:      sumnewm[cptcod]=0.;
                   7340:      sumnewp[cptcod]=0.;
                   7341:      agemingood[cptcod]=0;
                   7342:      agemaxgood[cptcod]=0;
                   7343:    }
                   7344:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   7345:   
                   7346:    if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   7347:      if(mobilav==1) mobilavrange=5; /* default */
                   7348:      else mobilavrange=mobilav;
                   7349:      for (age=bage; age<=fage; age++)
                   7350:        for (i=1; i<=nlstate;i++)
                   7351:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   7352:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   7353:      /* We keep the original values on the extreme ages bage, fage and for 
                   7354:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   7355:        we use a 5 terms etc. until the borders are no more concerned. 
                   7356:      */ 
                   7357:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   7358:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
                   7359:         for (i=1; i<=nlstate;i++){
                   7360:           for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7361:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   7362:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   7363:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   7364:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   7365:             }
                   7366:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
                   7367:           }
                   7368:         }
                   7369:        }/* end age */
                   7370:      }/* end mob */
                   7371:    }else
                   7372:      return -1;
                   7373:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7374:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7375:      if(invalidvarcomb[cptcod]){
                   7376:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7377:        continue;
                   7378:      }
1.219     brouard  7379: 
1.222     brouard  7380:      agemingood[cptcod]=fage-(mob-1)/2;
                   7381:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, finding the youngest wrong */
                   7382:        sumnewm[cptcod]=0.;
                   7383:        for (i=1; i<=nlstate;i++){
                   7384:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7385:        }
                   7386:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7387:         agemingood[cptcod]=age;
                   7388:        }else{ /* bad */
                   7389:         for (i=1; i<=nlstate;i++){
                   7390:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7391:         } /* i */
                   7392:        } /* end bad */
                   7393:      }/* age */
                   7394:      sum=0.;
                   7395:      for (i=1; i<=nlstate;i++){
                   7396:        sum+=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7397:      }
                   7398:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7399:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any descending age!\n",cptcod);
                   7400:        /* for (i=1; i<=nlstate;i++){ */
                   7401:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7402:        /* } /\* i *\/ */
                   7403:      } /* end bad */
                   7404:      /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   7405:      /* From youngest, finding the oldest wrong */
                   7406:      agemaxgood[cptcod]=bage+(mob-1)/2;
                   7407:      for (age=bage+(mob-1)/2; age<=fage; age++){
                   7408:        sumnewm[cptcod]=0.;
                   7409:        for (i=1; i<=nlstate;i++){
                   7410:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7411:        }
                   7412:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7413:         agemaxgood[cptcod]=age;
                   7414:        }else{ /* bad */
                   7415:         for (i=1; i<=nlstate;i++){
                   7416:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7417:         } /* i */
                   7418:        } /* end bad */
                   7419:      }/* age */
                   7420:      sum=0.;
                   7421:      for (i=1; i<=nlstate;i++){
                   7422:        sum+=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7423:      }
                   7424:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7425:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any ascending age!\n",cptcod);
                   7426:        /* for (i=1; i<=nlstate;i++){ */
                   7427:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7428:        /* } /\* i *\/ */
                   7429:      } /* end bad */
                   7430:                
                   7431:      for (age=bage; age<=fage; age++){
1.235     brouard  7432:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  7433:        sumnewp[cptcod]=0.;
                   7434:        sumnewm[cptcod]=0.;
                   7435:        for (i=1; i<=nlstate;i++){
                   7436:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   7437:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7438:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   7439:        }
                   7440:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   7441:      }
                   7442:      /* printf("\n"); */
                   7443:      /* } */
                   7444:      /* brutal averaging */
                   7445:      for (i=1; i<=nlstate;i++){
                   7446:        for (age=1; age<=bage; age++){
                   7447:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7448:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7449:        }       
                   7450:        for (age=fage; age<=AGESUP; age++){
                   7451:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7452:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7453:        }
                   7454:      } /* end i status */
                   7455:      for (i=nlstate+1; i<=nlstate+ndeath;i++){
                   7456:        for (age=1; age<=AGESUP; age++){
                   7457:         /*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*/
                   7458:         mobaverage[(int)age][i][cptcod]=0.;
                   7459:        }
                   7460:      }
                   7461:    }/* end cptcod */
                   7462:    free_vector(sumnewm,1, ncovcombmax);
                   7463:    free_vector(sumnewp,1, ncovcombmax);
                   7464:    free_vector(agemaxgood,1, ncovcombmax);
                   7465:    free_vector(agemingood,1, ncovcombmax);
                   7466:    return 0;
                   7467:  }/* End movingaverage */
1.218     brouard  7468:  
1.126     brouard  7469: 
                   7470: /************** Forecasting ******************/
1.235     brouard  7471:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  7472:   /* proj1, year, month, day of starting projection 
                   7473:      agemin, agemax range of age
                   7474:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   7475:      anproj2 year of en of projection (same day and month as proj1).
                   7476:   */
1.235     brouard  7477:    int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  7478:   double agec; /* generic age */
                   7479:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   7480:   double *popeffectif,*popcount;
                   7481:   double ***p3mat;
1.218     brouard  7482:   /* double ***mobaverage; */
1.126     brouard  7483:   char fileresf[FILENAMELENGTH];
                   7484: 
                   7485:   agelim=AGESUP;
1.211     brouard  7486:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   7487:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   7488:      We still use firstpass and lastpass as another selection.
                   7489:   */
1.214     brouard  7490:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   7491:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  7492:  
1.201     brouard  7493:   strcpy(fileresf,"F_"); 
                   7494:   strcat(fileresf,fileresu);
1.126     brouard  7495:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   7496:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   7497:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   7498:   }
1.235     brouard  7499:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   7500:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  7501: 
1.225     brouard  7502:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  7503: 
                   7504: 
                   7505:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   7506:   if (stepm<=12) stepsize=1;
                   7507:   if(estepm < stepm){
                   7508:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   7509:   }
                   7510:   else  hstepm=estepm;   
                   7511: 
                   7512:   hstepm=hstepm/stepm; 
                   7513:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   7514:                                fractional in yp1 */
                   7515:   anprojmean=yp;
                   7516:   yp2=modf((yp1*12),&yp);
                   7517:   mprojmean=yp;
                   7518:   yp1=modf((yp2*30.5),&yp);
                   7519:   jprojmean=yp;
                   7520:   if(jprojmean==0) jprojmean=1;
                   7521:   if(mprojmean==0) jprojmean=1;
                   7522: 
1.227     brouard  7523:   i1=pow(2,cptcoveff);
1.126     brouard  7524:   if (cptcovn < 1){i1=1;}
                   7525:   
                   7526:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   7527:   
                   7528:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  7529:   
1.126     brouard  7530: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  7531:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7532:   for(k=1; k<=i1;k++){
1.253     brouard  7533:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  7534:       continue;
1.227     brouard  7535:     if(invalidvarcomb[k]){
                   7536:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   7537:       continue;
                   7538:     }
                   7539:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   7540:     for(j=1;j<=cptcoveff;j++) {
                   7541:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7542:     }
1.235     brouard  7543:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7544:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  7545:     }
1.227     brouard  7546:     fprintf(ficresf," yearproj age");
                   7547:     for(j=1; j<=nlstate+ndeath;j++){ 
                   7548:       for(i=1; i<=nlstate;i++)               
                   7549:        fprintf(ficresf," p%d%d",i,j);
                   7550:       fprintf(ficresf," wp.%d",j);
                   7551:     }
                   7552:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   7553:       fprintf(ficresf,"\n");
                   7554:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
                   7555:       for (agec=fage; agec>=(ageminpar-1); agec--){ 
                   7556:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   7557:        nhstepm = nhstepm/hstepm; 
                   7558:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7559:        oldm=oldms;savm=savms;
1.235     brouard  7560:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.227     brouard  7561:        
                   7562:        for (h=0; h<=nhstepm; h++){
                   7563:          if (h*hstepm/YEARM*stepm ==yearp) {
                   7564:            fprintf(ficresf,"\n");
                   7565:            for(j=1;j<=cptcoveff;j++) 
                   7566:              fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7567:            fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   7568:          } 
                   7569:          for(j=1; j<=nlstate+ndeath;j++) {
                   7570:            ppij=0.;
                   7571:            for(i=1; i<=nlstate;i++) {
                   7572:              if (mobilav==1) 
                   7573:                ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][k];
                   7574:              else {
                   7575:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   7576:              }
                   7577:              if (h*hstepm/YEARM*stepm== yearp) {
                   7578:                fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   7579:              }
                   7580:            } /* end i */
                   7581:            if (h*hstepm/YEARM*stepm==yearp) {
                   7582:              fprintf(ficresf," %.3f", ppij);
                   7583:            }
                   7584:          }/* end j */
                   7585:        } /* end h */
                   7586:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7587:       } /* end agec */
                   7588:     } /* end yearp */
                   7589:   } /* end  k */
1.219     brouard  7590:        
1.126     brouard  7591:   fclose(ficresf);
1.215     brouard  7592:   printf("End of Computing forecasting \n");
                   7593:   fprintf(ficlog,"End of Computing forecasting\n");
                   7594: 
1.126     brouard  7595: }
                   7596: 
1.218     brouard  7597: /* /\************** Back Forecasting ******************\/ */
1.225     brouard  7598: /* void prevbackforecast(char fileres[], double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
1.218     brouard  7599: /*   /\* back1, year, month, day of starting backection  */
                   7600: /*      agemin, agemax range of age */
                   7601: /*      dateprev1 dateprev2 range of dates during which prevalence is computed */
                   7602: /*      anback2 year of en of backection (same day and month as back1). */
                   7603: /*   *\/ */
                   7604: /*   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1; */
                   7605: /*   double agec; /\* generic age *\/ */
                   7606: /*   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean; */
                   7607: /*   double *popeffectif,*popcount; */
                   7608: /*   double ***p3mat; */
                   7609: /*   /\* double ***mobaverage; *\/ */
                   7610: /*   char fileresfb[FILENAMELENGTH]; */
                   7611:        
                   7612: /*   agelim=AGESUP; */
                   7613: /*   /\* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people */
                   7614: /*      in each health status at the date of interview (if between dateprev1 and dateprev2). */
                   7615: /*      We still use firstpass and lastpass as another selection. */
                   7616: /*   *\/ */
                   7617: /*   /\* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ *\/ */
                   7618: /*   /\*             firstpass, lastpass,  stepm,  weightopt, model); *\/ */
                   7619: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   7620:        
                   7621: /*   strcpy(fileresfb,"FB_");  */
                   7622: /*   strcat(fileresfb,fileresu); */
                   7623: /*   if((ficresfb=fopen(fileresfb,"w"))==NULL) { */
                   7624: /*     printf("Problem with back forecast resultfile: %s\n", fileresfb); */
                   7625: /*     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb); */
                   7626: /*   } */
                   7627: /*   printf("Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7628: /*   fprintf(ficlog,"Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7629:        
1.225     brouard  7630: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.218     brouard  7631:        
                   7632: /*   /\* if (mobilav!=0) { *\/ */
                   7633: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7634: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7635: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7636: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7637: /*   /\*   } *\/ */
                   7638: /*   /\* } *\/ */
                   7639:        
                   7640: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7641: /*   if (stepm<=12) stepsize=1; */
                   7642: /*   if(estepm < stepm){ */
                   7643: /*     printf ("Problem %d lower than %d\n",estepm, stepm); */
                   7644: /*   } */
                   7645: /*   else  hstepm=estepm;    */
                   7646:        
                   7647: /*   hstepm=hstepm/stepm;  */
                   7648: /*   yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   7649: /*                                fractional in yp1 *\/ */
                   7650: /*   anprojmean=yp; */
                   7651: /*   yp2=modf((yp1*12),&yp); */
                   7652: /*   mprojmean=yp; */
                   7653: /*   yp1=modf((yp2*30.5),&yp); */
                   7654: /*   jprojmean=yp; */
                   7655: /*   if(jprojmean==0) jprojmean=1; */
                   7656: /*   if(mprojmean==0) jprojmean=1; */
                   7657:        
1.225     brouard  7658: /*   i1=cptcoveff; */
1.218     brouard  7659: /*   if (cptcovn < 1){i1=1;} */
1.217     brouard  7660:   
1.218     brouard  7661: /*   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);  */
1.217     brouard  7662:   
1.218     brouard  7663: /*   fprintf(ficresfb,"#****** Routine prevbackforecast **\n"); */
                   7664:        
                   7665: /*     /\*           if (h==(int)(YEARM*yearp)){ *\/ */
                   7666: /*   for(cptcov=1, k=0;cptcov<=i1;cptcov++){ */
1.225     brouard  7667: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
1.218     brouard  7668: /*       k=k+1; */
                   7669: /*       fprintf(ficresfb,"\n#****** hbijx=probability over h years, hp.jx is weighted by observed prev \n#"); */
1.225     brouard  7670: /*       for(j=1;j<=cptcoveff;j++) { */
1.218     brouard  7671: /*                             fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7672: /*       } */
                   7673: /*       fprintf(ficresfb," yearbproj age"); */
                   7674: /*       for(j=1; j<=nlstate+ndeath;j++){  */
                   7675: /*                             for(i=1; i<=nlstate;i++)               */
                   7676: /*           fprintf(ficresfb," p%d%d",i,j); */
                   7677: /*                             fprintf(ficresfb," p.%d",j); */
                   7678: /*       } */
                   7679: /*       for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {  */
                   7680: /*                             /\* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  *\/ */
                   7681: /*                             fprintf(ficresfb,"\n"); */
                   7682: /*                             fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);    */
                   7683: /*                             for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   7684: /*                                     nhstepm=(int) rint((agelim-agec)*YEARM/stepm);  */
                   7685: /*                                     nhstepm = nhstepm/hstepm;  */
                   7686: /*                                     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7687: /*                                     oldm=oldms;savm=savms; */
                   7688: /*                                     hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm,oldm,savm, dnewm, doldm, dsavm, k);       */
                   7689: /*                                     for (h=0; h<=nhstepm; h++){ */
                   7690: /*                                             if (h*hstepm/YEARM*stepm ==yearp) { */
                   7691: /*               fprintf(ficresfb,"\n"); */
1.225     brouard  7692: /*               for(j=1;j<=cptcoveff;j++)  */
1.218     brouard  7693: /*                 fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7694: /*                                                     fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec+h*hstepm/YEARM*stepm); */
                   7695: /*                                             }  */
                   7696: /*                                             for(j=1; j<=nlstate+ndeath;j++) { */
                   7697: /*                                                     ppij=0.; */
                   7698: /*                                                     for(i=1; i<=nlstate;i++) { */
                   7699: /*                                                             if (mobilav==1)  */
                   7700: /*                                                                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod]; */
                   7701: /*                                                             else { */
                   7702: /*                                                                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod]; */
                   7703: /*                                                             } */
                   7704: /*                                                             if (h*hstepm/YEARM*stepm== yearp) { */
                   7705: /*                                                                     fprintf(ficresfb," %.3f", p3mat[i][j][h]); */
                   7706: /*                                                             } */
                   7707: /*                                                     } /\* end i *\/ */
                   7708: /*                                                     if (h*hstepm/YEARM*stepm==yearp) { */
                   7709: /*                                                             fprintf(ficresfb," %.3f", ppij); */
                   7710: /*                                                     } */
                   7711: /*                                             }/\* end j *\/ */
                   7712: /*                                     } /\* end h *\/ */
                   7713: /*                                     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7714: /*                             } /\* end agec *\/ */
                   7715: /*       } /\* end yearp *\/ */
                   7716: /*     } /\* end cptcod *\/ */
                   7717: /*   } /\* end  cptcov *\/ */
                   7718:        
                   7719: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7720:        
                   7721: /*   fclose(ficresfb); */
                   7722: /*   printf("End of Computing Back forecasting \n"); */
                   7723: /*   fprintf(ficlog,"End of Computing Back forecasting\n"); */
1.217     brouard  7724:        
1.218     brouard  7725: /* } */
1.217     brouard  7726: 
1.126     brouard  7727: /************** Forecasting *****not tested NB*************/
1.227     brouard  7728: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  7729:   
1.227     brouard  7730: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   7731: /*   int *popage; */
                   7732: /*   double calagedatem, agelim, kk1, kk2; */
                   7733: /*   double *popeffectif,*popcount; */
                   7734: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   7735: /*   /\* double ***mobaverage; *\/ */
                   7736: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  7737: 
1.227     brouard  7738: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7739: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7740: /*   agelim=AGESUP; */
                   7741: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  7742:   
1.227     brouard  7743: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  7744:   
                   7745:   
1.227     brouard  7746: /*   strcpy(filerespop,"POP_");  */
                   7747: /*   strcat(filerespop,fileresu); */
                   7748: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   7749: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   7750: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   7751: /*   } */
                   7752: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   7753: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  7754: 
1.227     brouard  7755: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  7756: 
1.227     brouard  7757: /*   /\* if (mobilav!=0) { *\/ */
                   7758: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7759: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7760: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7761: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7762: /*   /\*   } *\/ */
                   7763: /*   /\* } *\/ */
1.126     brouard  7764: 
1.227     brouard  7765: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7766: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  7767:   
1.227     brouard  7768: /*   agelim=AGESUP; */
1.126     brouard  7769:   
1.227     brouard  7770: /*   hstepm=1; */
                   7771: /*   hstepm=hstepm/stepm;  */
1.218     brouard  7772:        
1.227     brouard  7773: /*   if (popforecast==1) { */
                   7774: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   7775: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   7776: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   7777: /*     }  */
                   7778: /*     popage=ivector(0,AGESUP); */
                   7779: /*     popeffectif=vector(0,AGESUP); */
                   7780: /*     popcount=vector(0,AGESUP); */
1.126     brouard  7781:     
1.227     brouard  7782: /*     i=1;    */
                   7783: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  7784:     
1.227     brouard  7785: /*     imx=i; */
                   7786: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   7787: /*   } */
1.218     brouard  7788:   
1.227     brouard  7789: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   7790: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   7791: /*       k=k+1; */
                   7792: /*       fprintf(ficrespop,"\n#******"); */
                   7793: /*       for(j=1;j<=cptcoveff;j++) { */
                   7794: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7795: /*       } */
                   7796: /*       fprintf(ficrespop,"******\n"); */
                   7797: /*       fprintf(ficrespop,"# Age"); */
                   7798: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   7799: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  7800:       
1.227     brouard  7801: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   7802: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  7803:        
1.227     brouard  7804: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7805: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7806: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7807:          
1.227     brouard  7808: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7809: /*       oldm=oldms;savm=savms; */
                   7810: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  7811:          
1.227     brouard  7812: /*       for (h=0; h<=nhstepm; h++){ */
                   7813: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7814: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7815: /*         }  */
                   7816: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7817: /*           kk1=0.;kk2=0; */
                   7818: /*           for(i=1; i<=nlstate;i++) {               */
                   7819: /*             if (mobilav==1)  */
                   7820: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   7821: /*             else { */
                   7822: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   7823: /*             } */
                   7824: /*           } */
                   7825: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   7826: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   7827: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   7828: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   7829: /*           } */
                   7830: /*         } */
                   7831: /*         for(i=1; i<=nlstate;i++){ */
                   7832: /*           kk1=0.; */
                   7833: /*           for(j=1; j<=nlstate;j++){ */
                   7834: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   7835: /*           } */
                   7836: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   7837: /*         } */
1.218     brouard  7838:            
1.227     brouard  7839: /*         if (h==(int)(calagedatem+12*cpt)) */
                   7840: /*           for(j=1; j<=nlstate;j++)  */
                   7841: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   7842: /*       } */
                   7843: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7844: /*     } */
                   7845: /*       } */
1.218     brouard  7846:       
1.227     brouard  7847: /*       /\******\/ */
1.218     brouard  7848:       
1.227     brouard  7849: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   7850: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   7851: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7852: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7853: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7854:          
1.227     brouard  7855: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7856: /*       oldm=oldms;savm=savms; */
                   7857: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   7858: /*       for (h=0; h<=nhstepm; h++){ */
                   7859: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7860: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7861: /*         }  */
                   7862: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7863: /*           kk1=0.;kk2=0; */
                   7864: /*           for(i=1; i<=nlstate;i++) {               */
                   7865: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   7866: /*           } */
                   7867: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   7868: /*         } */
                   7869: /*       } */
                   7870: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7871: /*     } */
                   7872: /*       } */
                   7873: /*     }  */
                   7874: /*   } */
1.218     brouard  7875:   
1.227     brouard  7876: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  7877:   
1.227     brouard  7878: /*   if (popforecast==1) { */
                   7879: /*     free_ivector(popage,0,AGESUP); */
                   7880: /*     free_vector(popeffectif,0,AGESUP); */
                   7881: /*     free_vector(popcount,0,AGESUP); */
                   7882: /*   } */
                   7883: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7884: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7885: /*   fclose(ficrespop); */
                   7886: /* } /\* End of popforecast *\/ */
1.218     brouard  7887:  
1.126     brouard  7888: int fileappend(FILE *fichier, char *optionfich)
                   7889: {
                   7890:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   7891:     printf("Problem with file: %s\n", optionfich);
                   7892:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   7893:     return (0);
                   7894:   }
                   7895:   fflush(fichier);
                   7896:   return (1);
                   7897: }
                   7898: 
                   7899: 
                   7900: /**************** function prwizard **********************/
                   7901: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   7902: {
                   7903: 
                   7904:   /* Wizard to print covariance matrix template */
                   7905: 
1.164     brouard  7906:   char ca[32], cb[32];
                   7907:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  7908:   int numlinepar;
                   7909: 
                   7910:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7911:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7912:   for(i=1; i <=nlstate; i++){
                   7913:     jj=0;
                   7914:     for(j=1; j <=nlstate+ndeath; j++){
                   7915:       if(j==i) continue;
                   7916:       jj++;
                   7917:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   7918:       printf("%1d%1d",i,j);
                   7919:       fprintf(ficparo,"%1d%1d",i,j);
                   7920:       for(k=1; k<=ncovmodel;k++){
                   7921:        /*        printf(" %lf",param[i][j][k]); */
                   7922:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   7923:        printf(" 0.");
                   7924:        fprintf(ficparo," 0.");
                   7925:       }
                   7926:       printf("\n");
                   7927:       fprintf(ficparo,"\n");
                   7928:     }
                   7929:   }
                   7930:   printf("# Scales (for hessian or gradient estimation)\n");
                   7931:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   7932:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   7933:   for(i=1; i <=nlstate; i++){
                   7934:     jj=0;
                   7935:     for(j=1; j <=nlstate+ndeath; j++){
                   7936:       if(j==i) continue;
                   7937:       jj++;
                   7938:       fprintf(ficparo,"%1d%1d",i,j);
                   7939:       printf("%1d%1d",i,j);
                   7940:       fflush(stdout);
                   7941:       for(k=1; k<=ncovmodel;k++){
                   7942:        /*      printf(" %le",delti3[i][j][k]); */
                   7943:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   7944:        printf(" 0.");
                   7945:        fprintf(ficparo," 0.");
                   7946:       }
                   7947:       numlinepar++;
                   7948:       printf("\n");
                   7949:       fprintf(ficparo,"\n");
                   7950:     }
                   7951:   }
                   7952:   printf("# Covariance matrix\n");
                   7953: /* # 121 Var(a12)\n\ */
                   7954: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7955: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   7956: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   7957: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   7958: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   7959: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   7960: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   7961:   fflush(stdout);
                   7962:   fprintf(ficparo,"# Covariance matrix\n");
                   7963:   /* # 121 Var(a12)\n\ */
                   7964:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7965:   /* #   ...\n\ */
                   7966:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   7967:   
                   7968:   for(itimes=1;itimes<=2;itimes++){
                   7969:     jj=0;
                   7970:     for(i=1; i <=nlstate; i++){
                   7971:       for(j=1; j <=nlstate+ndeath; j++){
                   7972:        if(j==i) continue;
                   7973:        for(k=1; k<=ncovmodel;k++){
                   7974:          jj++;
                   7975:          ca[0]= k+'a'-1;ca[1]='\0';
                   7976:          if(itimes==1){
                   7977:            printf("#%1d%1d%d",i,j,k);
                   7978:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   7979:          }else{
                   7980:            printf("%1d%1d%d",i,j,k);
                   7981:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   7982:            /*  printf(" %.5le",matcov[i][j]); */
                   7983:          }
                   7984:          ll=0;
                   7985:          for(li=1;li <=nlstate; li++){
                   7986:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   7987:              if(lj==li) continue;
                   7988:              for(lk=1;lk<=ncovmodel;lk++){
                   7989:                ll++;
                   7990:                if(ll<=jj){
                   7991:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   7992:                  if(ll<jj){
                   7993:                    if(itimes==1){
                   7994:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7995:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7996:                    }else{
                   7997:                      printf(" 0.");
                   7998:                      fprintf(ficparo," 0.");
                   7999:                    }
                   8000:                  }else{
                   8001:                    if(itimes==1){
                   8002:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8003:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8004:                    }else{
                   8005:                      printf(" 0.");
                   8006:                      fprintf(ficparo," 0.");
                   8007:                    }
                   8008:                  }
                   8009:                }
                   8010:              } /* end lk */
                   8011:            } /* end lj */
                   8012:          } /* end li */
                   8013:          printf("\n");
                   8014:          fprintf(ficparo,"\n");
                   8015:          numlinepar++;
                   8016:        } /* end k*/
                   8017:       } /*end j */
                   8018:     } /* end i */
                   8019:   } /* end itimes */
                   8020: 
                   8021: } /* end of prwizard */
                   8022: /******************* Gompertz Likelihood ******************************/
                   8023: double gompertz(double x[])
                   8024: { 
                   8025:   double A,B,L=0.0,sump=0.,num=0.;
                   8026:   int i,n=0; /* n is the size of the sample */
                   8027: 
1.220     brouard  8028:   for (i=1;i<=imx ; i++) {
1.126     brouard  8029:     sump=sump+weight[i];
                   8030:     /*    sump=sump+1;*/
                   8031:     num=num+1;
                   8032:   }
                   8033:  
                   8034:  
                   8035:   /* for (i=0; i<=imx; i++) 
                   8036:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8037: 
                   8038:   for (i=1;i<=imx ; i++)
                   8039:     {
                   8040:       if (cens[i] == 1 && wav[i]>1)
                   8041:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8042:       
                   8043:       if (cens[i] == 0 && wav[i]>1)
                   8044:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8045:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8046:       
                   8047:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8048:       if (wav[i] > 1 ) { /* ??? */
                   8049:        L=L+A*weight[i];
                   8050:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8051:       }
                   8052:     }
                   8053: 
                   8054:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8055:  
                   8056:   return -2*L*num/sump;
                   8057: }
                   8058: 
1.136     brouard  8059: #ifdef GSL
                   8060: /******************* Gompertz_f Likelihood ******************************/
                   8061: double gompertz_f(const gsl_vector *v, void *params)
                   8062: { 
                   8063:   double A,B,LL=0.0,sump=0.,num=0.;
                   8064:   double *x= (double *) v->data;
                   8065:   int i,n=0; /* n is the size of the sample */
                   8066: 
                   8067:   for (i=0;i<=imx-1 ; i++) {
                   8068:     sump=sump+weight[i];
                   8069:     /*    sump=sump+1;*/
                   8070:     num=num+1;
                   8071:   }
                   8072:  
                   8073:  
                   8074:   /* for (i=0; i<=imx; i++) 
                   8075:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8076:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   8077:   for (i=1;i<=imx ; i++)
                   8078:     {
                   8079:       if (cens[i] == 1 && wav[i]>1)
                   8080:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   8081:       
                   8082:       if (cens[i] == 0 && wav[i]>1)
                   8083:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   8084:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   8085:       
                   8086:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8087:       if (wav[i] > 1 ) { /* ??? */
                   8088:        LL=LL+A*weight[i];
                   8089:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8090:       }
                   8091:     }
                   8092: 
                   8093:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8094:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   8095:  
                   8096:   return -2*LL*num/sump;
                   8097: }
                   8098: #endif
                   8099: 
1.126     brouard  8100: /******************* Printing html file ***********/
1.201     brouard  8101: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  8102:                  int lastpass, int stepm, int weightopt, char model[],\
                   8103:                  int imx,  double p[],double **matcov,double agemortsup){
                   8104:   int i,k;
                   8105: 
                   8106:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   8107:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   8108:   for (i=1;i<=2;i++) 
                   8109:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  8110:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  8111:   fprintf(fichtm,"</ul>");
                   8112: 
                   8113: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   8114: 
                   8115:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   8116: 
                   8117:  for (k=agegomp;k<(agemortsup-2);k++) 
                   8118:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   8119: 
                   8120:  
                   8121:   fflush(fichtm);
                   8122: }
                   8123: 
                   8124: /******************* Gnuplot file **************/
1.201     brouard  8125: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  8126: 
                   8127:   char dirfileres[132],optfileres[132];
1.164     brouard  8128: 
1.126     brouard  8129:   int ng;
                   8130: 
                   8131: 
                   8132:   /*#ifdef windows */
                   8133:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   8134:     /*#endif */
                   8135: 
                   8136: 
                   8137:   strcpy(dirfileres,optionfilefiname);
                   8138:   strcpy(optfileres,"vpl");
1.199     brouard  8139:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  8140:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  8141:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  8142:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  8143:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   8144: 
                   8145: } 
                   8146: 
1.136     brouard  8147: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   8148: {
1.126     brouard  8149: 
1.136     brouard  8150:   /*-------- data file ----------*/
                   8151:   FILE *fic;
                   8152:   char dummy[]="                         ";
1.240     brouard  8153:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  8154:   int lstra;
1.136     brouard  8155:   int linei, month, year,iout;
                   8156:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  8157:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  8158:   char *stratrunc;
1.223     brouard  8159: 
1.240     brouard  8160:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   8161:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  8162: 
1.240     brouard  8163:   for(v=1; v <=ncovcol;v++){
                   8164:     DummyV[v]=0;
                   8165:     FixedV[v]=0;
                   8166:   }
                   8167:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   8168:     DummyV[v]=1;
                   8169:     FixedV[v]=0;
                   8170:   }
                   8171:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   8172:     DummyV[v]=0;
                   8173:     FixedV[v]=1;
                   8174:   }
                   8175:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8176:     DummyV[v]=1;
                   8177:     FixedV[v]=1;
                   8178:   }
                   8179:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8180:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8181:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8182:   }
1.126     brouard  8183: 
1.136     brouard  8184:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  8185:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   8186:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  8187:   }
1.126     brouard  8188: 
1.136     brouard  8189:   i=1;
                   8190:   linei=0;
                   8191:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   8192:     linei=linei+1;
                   8193:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   8194:       if(line[j] == '\t')
                   8195:        line[j] = ' ';
                   8196:     }
                   8197:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   8198:       ;
                   8199:     };
                   8200:     line[j+1]=0;  /* Trims blanks at end of line */
                   8201:     if(line[0]=='#'){
                   8202:       fprintf(ficlog,"Comment line\n%s\n",line);
                   8203:       printf("Comment line\n%s\n",line);
                   8204:       continue;
                   8205:     }
                   8206:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  8207:     strcpy(line, linetmp);
1.223     brouard  8208:     
                   8209:     /* Loops on waves */
                   8210:     for (j=maxwav;j>=1;j--){
                   8211:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  8212:        cutv(stra, strb, line, ' '); 
                   8213:        if(strb[0]=='.') { /* Missing value */
                   8214:          lval=-1;
                   8215:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   8216:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   8217:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   8218:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   8219:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   8220:            return 1;
                   8221:          }
                   8222:        }else{
                   8223:          errno=0;
                   8224:          /* what_kind_of_number(strb); */
                   8225:          dval=strtod(strb,&endptr); 
                   8226:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   8227:          /* if(strb != endptr && *endptr == '\0') */
                   8228:          /*    dval=dlval; */
                   8229:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8230:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8231:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   8232:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   8233:            return 1;
                   8234:          }
                   8235:          cotqvar[j][iv][i]=dval; 
                   8236:          cotvar[j][ntv+iv][i]=dval; 
                   8237:        }
                   8238:        strcpy(line,stra);
1.223     brouard  8239:       }/* end loop ntqv */
1.225     brouard  8240:       
1.223     brouard  8241:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  8242:        cutv(stra, strb, line, ' '); 
                   8243:        if(strb[0]=='.') { /* Missing value */
                   8244:          lval=-1;
                   8245:        }else{
                   8246:          errno=0;
                   8247:          lval=strtol(strb,&endptr,10); 
                   8248:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8249:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8250:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   8251:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   8252:            return 1;
                   8253:          }
                   8254:        }
                   8255:        if(lval <-1 || lval >1){
                   8256:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8257:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8258:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8259:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8260:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8261:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8262:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8263:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8264:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  8265:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8266:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8267:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8268:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8269:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8270:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8271:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8272:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8273:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  8274:          return 1;
                   8275:        }
                   8276:        cotvar[j][iv][i]=(double)(lval);
                   8277:        strcpy(line,stra);
1.223     brouard  8278:       }/* end loop ntv */
1.225     brouard  8279:       
1.223     brouard  8280:       /* Statuses  at wave */
1.137     brouard  8281:       cutv(stra, strb, line, ' '); 
1.223     brouard  8282:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  8283:        lval=-1;
1.136     brouard  8284:       }else{
1.238     brouard  8285:        errno=0;
                   8286:        lval=strtol(strb,&endptr,10); 
                   8287:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8288:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8289:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   8290:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   8291:          return 1;
                   8292:        }
1.136     brouard  8293:       }
1.225     brouard  8294:       
1.136     brouard  8295:       s[j][i]=lval;
1.225     brouard  8296:       
1.223     brouard  8297:       /* Date of Interview */
1.136     brouard  8298:       strcpy(line,stra);
                   8299:       cutv(stra, strb,line,' ');
1.169     brouard  8300:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8301:       }
1.169     brouard  8302:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  8303:        month=99;
                   8304:        year=9999;
1.136     brouard  8305:       }else{
1.225     brouard  8306:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   8307:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   8308:        return 1;
1.136     brouard  8309:       }
                   8310:       anint[j][i]= (double) year; 
                   8311:       mint[j][i]= (double)month; 
                   8312:       strcpy(line,stra);
1.223     brouard  8313:     } /* End loop on waves */
1.225     brouard  8314:     
1.223     brouard  8315:     /* Date of death */
1.136     brouard  8316:     cutv(stra, strb,line,' '); 
1.169     brouard  8317:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8318:     }
1.169     brouard  8319:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  8320:       month=99;
                   8321:       year=9999;
                   8322:     }else{
1.141     brouard  8323:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  8324:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   8325:       return 1;
1.136     brouard  8326:     }
                   8327:     andc[i]=(double) year; 
                   8328:     moisdc[i]=(double) month; 
                   8329:     strcpy(line,stra);
                   8330:     
1.223     brouard  8331:     /* Date of birth */
1.136     brouard  8332:     cutv(stra, strb,line,' '); 
1.169     brouard  8333:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8334:     }
1.169     brouard  8335:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  8336:       month=99;
                   8337:       year=9999;
                   8338:     }else{
1.141     brouard  8339:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   8340:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8341:       return 1;
1.136     brouard  8342:     }
                   8343:     if (year==9999) {
1.141     brouard  8344:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   8345:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8346:       return 1;
                   8347:       
1.136     brouard  8348:     }
                   8349:     annais[i]=(double)(year);
                   8350:     moisnais[i]=(double)(month); 
                   8351:     strcpy(line,stra);
1.225     brouard  8352:     
1.223     brouard  8353:     /* Sample weight */
1.136     brouard  8354:     cutv(stra, strb,line,' '); 
                   8355:     errno=0;
                   8356:     dval=strtod(strb,&endptr); 
                   8357:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  8358:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   8359:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  8360:       fflush(ficlog);
                   8361:       return 1;
                   8362:     }
                   8363:     weight[i]=dval; 
                   8364:     strcpy(line,stra);
1.225     brouard  8365:     
1.223     brouard  8366:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   8367:       cutv(stra, strb, line, ' '); 
                   8368:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  8369:        lval=-1;
1.223     brouard  8370:       }else{
1.225     brouard  8371:        errno=0;
                   8372:        /* what_kind_of_number(strb); */
                   8373:        dval=strtod(strb,&endptr);
                   8374:        /* if(strb != endptr && *endptr == '\0') */
                   8375:        /*   dval=dlval; */
                   8376:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8377:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8378:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   8379:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   8380:          return 1;
                   8381:        }
                   8382:        coqvar[iv][i]=dval; 
1.226     brouard  8383:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  8384:       }
                   8385:       strcpy(line,stra);
                   8386:     }/* end loop nqv */
1.136     brouard  8387:     
1.223     brouard  8388:     /* Covariate values */
1.136     brouard  8389:     for (j=ncovcol;j>=1;j--){
                   8390:       cutv(stra, strb,line,' '); 
1.223     brouard  8391:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  8392:        lval=-1;
1.136     brouard  8393:       }else{
1.225     brouard  8394:        errno=0;
                   8395:        lval=strtol(strb,&endptr,10); 
                   8396:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8397:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   8398:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   8399:          return 1;
                   8400:        }
1.136     brouard  8401:       }
                   8402:       if(lval <-1 || lval >1){
1.225     brouard  8403:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8404:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8405:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8406:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8407:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8408:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8409:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8410:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8411:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  8412:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8413:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8414:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8415:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8416:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8417:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8418:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8419:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8420:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  8421:        return 1;
1.136     brouard  8422:       }
                   8423:       covar[j][i]=(double)(lval);
                   8424:       strcpy(line,stra);
                   8425:     }  
                   8426:     lstra=strlen(stra);
1.225     brouard  8427:     
1.136     brouard  8428:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   8429:       stratrunc = &(stra[lstra-9]);
                   8430:       num[i]=atol(stratrunc);
                   8431:     }
                   8432:     else
                   8433:       num[i]=atol(stra);
                   8434:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   8435:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   8436:     
                   8437:     i=i+1;
                   8438:   } /* End loop reading  data */
1.225     brouard  8439:   
1.136     brouard  8440:   *imax=i-1; /* Number of individuals */
                   8441:   fclose(fic);
1.225     brouard  8442:   
1.136     brouard  8443:   return (0);
1.164     brouard  8444:   /* endread: */
1.225     brouard  8445:   printf("Exiting readdata: ");
                   8446:   fclose(fic);
                   8447:   return (1);
1.223     brouard  8448: }
1.126     brouard  8449: 
1.234     brouard  8450: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  8451:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  8452:   while (*p2 == ' ')
1.234     brouard  8453:     p2++; 
                   8454:   /* while ((*p1++ = *p2++) !=0) */
                   8455:   /*   ; */
                   8456:   /* do */
                   8457:   /*   while (*p2 == ' ') */
                   8458:   /*     p2++; */
                   8459:   /* while (*p1++ == *p2++); */
                   8460:   *stri=p2; 
1.145     brouard  8461: }
                   8462: 
1.235     brouard  8463: int decoderesult ( char resultline[], int nres)
1.230     brouard  8464: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   8465: {
1.235     brouard  8466:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  8467:   char resultsav[MAXLINE];
1.234     brouard  8468:   int resultmodel[MAXLINE];
                   8469:   int modelresult[MAXLINE];
1.230     brouard  8470:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   8471: 
1.234     brouard  8472:   removefirstspace(&resultline);
1.233     brouard  8473:   printf("decoderesult:%s\n",resultline);
1.230     brouard  8474: 
                   8475:   if (strstr(resultline,"v") !=0){
                   8476:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   8477:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   8478:     return 1;
                   8479:   }
                   8480:   trimbb(resultsav, resultline);
                   8481:   if (strlen(resultsav) >1){
                   8482:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   8483:   }
1.253     brouard  8484:   if(j == 0){ /* Resultline but no = */
                   8485:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   8486:     return (0);
                   8487:   }
                   8488:     
1.234     brouard  8489:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   8490:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8491:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8492:   }
                   8493:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   8494:     if(nbocc(resultsav,'=') >1){
                   8495:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   8496:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   8497:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   8498:     }else
                   8499:       cutl(strc,strd,resultsav,'=');
1.230     brouard  8500:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  8501:     
1.230     brouard  8502:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   8503:     Tvarsel[k]=atoi(strc);
                   8504:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   8505:     /* cptcovsel++;     */
                   8506:     if (nbocc(stra,'=') >0)
                   8507:       strcpy(resultsav,stra); /* and analyzes it */
                   8508:   }
1.235     brouard  8509:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  8510:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8511:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  8512:       match=0;
1.236     brouard  8513:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  8514:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  8515:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  8516:          match=1;
                   8517:          break;
                   8518:        }
                   8519:       }
                   8520:       if(match == 0){
                   8521:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8522:       }
                   8523:     }
                   8524:   }
1.235     brouard  8525:   /* Checking for missing or useless values in comparison of current model needs */
                   8526:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  8527:     match=0;
1.235     brouard  8528:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8529:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  8530:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  8531:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  8532:          ++match;
                   8533:        }
                   8534:       }
                   8535:     }
                   8536:     if(match == 0){
                   8537:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8538:     }else if(match > 1){
                   8539:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   8540:     }
                   8541:   }
1.235     brouard  8542:       
1.234     brouard  8543:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  8544:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8545:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   8546:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   8547:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   8548:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   8549:   /*    1 0 0 0 */
                   8550:   /*    2 1 0 0 */
                   8551:   /*    3 0 1 0 */ 
                   8552:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   8553:   /*    5 0 0 1 */
                   8554:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   8555:   /*    7 0 1 1 */
                   8556:   /*    8 1 1 1 */
1.237     brouard  8557:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   8558:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   8559:   /* V5*age V5 known which value for nres?  */
                   8560:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  8561:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   8562:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  8563:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  8564:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   8565:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  8566:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   8567:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   8568:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  8569:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   8570:       k4++;;
                   8571:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   8572:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   8573:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  8574:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   8575:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   8576:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  8577:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   8578:       k4q++;;
                   8579:     }
                   8580:   }
1.234     brouard  8581:   
1.235     brouard  8582:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  8583:   return (0);
                   8584: }
1.235     brouard  8585: 
1.230     brouard  8586: int decodemodel( char model[], int lastobs)
                   8587:  /**< This routine decodes the model and returns:
1.224     brouard  8588:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   8589:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   8590:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   8591:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   8592:        * - cptcovage number of covariates with age*products =2
                   8593:        * - cptcovs number of simple covariates
                   8594:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   8595:        *     which is a new column after the 9 (ncovcol) variables. 
                   8596:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   8597:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   8598:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   8599:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   8600:        */
1.136     brouard  8601: {
1.238     brouard  8602:   int i, j, k, ks, v;
1.227     brouard  8603:   int  j1, k1, k2, k3, k4;
1.136     brouard  8604:   char modelsav[80];
1.145     brouard  8605:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  8606:   char *strpt;
1.136     brouard  8607: 
1.145     brouard  8608:   /*removespace(model);*/
1.136     brouard  8609:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  8610:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  8611:     if (strstr(model,"AGE") !=0){
1.192     brouard  8612:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   8613:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  8614:       return 1;
                   8615:     }
1.141     brouard  8616:     if (strstr(model,"v") !=0){
                   8617:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   8618:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   8619:       return 1;
                   8620:     }
1.187     brouard  8621:     strcpy(modelsav,model); 
                   8622:     if ((strpt=strstr(model,"age*age")) !=0){
                   8623:       printf(" strpt=%s, model=%s\n",strpt, model);
                   8624:       if(strpt != model){
1.234     brouard  8625:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8626:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8627:  corresponding column of parameters.\n",model);
1.234     brouard  8628:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8629:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8630:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  8631:        return 1;
1.225     brouard  8632:       }
1.187     brouard  8633:       nagesqr=1;
                   8634:       if (strstr(model,"+age*age") !=0)
1.234     brouard  8635:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  8636:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  8637:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  8638:       else 
1.234     brouard  8639:        substrchaine(modelsav, model, "age*age");
1.187     brouard  8640:     }else
                   8641:       nagesqr=0;
                   8642:     if (strlen(modelsav) >1){
                   8643:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   8644:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  8645:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  8646:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  8647:                     * cst, age and age*age 
                   8648:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   8649:       /* including age products which are counted in cptcovage.
                   8650:        * but the covariates which are products must be treated 
                   8651:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  8652:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   8653:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  8654:       
                   8655:       
1.187     brouard  8656:       /*   Design
                   8657:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   8658:        *  <          ncovcol=8                >
                   8659:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   8660:        *   k=  1    2      3       4     5       6      7        8
                   8661:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   8662:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  8663:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   8664:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  8665:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   8666:        *  Tage[++cptcovage]=k
                   8667:        *       if products, new covar are created after ncovcol with k1
                   8668:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   8669:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   8670:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   8671:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   8672:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   8673:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   8674:        *  <          ncovcol=8                >
                   8675:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   8676:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   8677:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   8678:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8679:        * p Tprod[1]@2={                         6, 5}
                   8680:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   8681:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   8682:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   8683:        *How to reorganize?
                   8684:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   8685:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8686:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   8687:        * Struct []
                   8688:        */
1.225     brouard  8689:       
1.187     brouard  8690:       /* This loop fills the array Tvar from the string 'model'.*/
                   8691:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   8692:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   8693:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   8694:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   8695:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   8696:       /*       k=1 Tvar[1]=2 (from V2) */
                   8697:       /*       k=5 Tvar[5] */
                   8698:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  8699:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  8700:       /*       } */
1.198     brouard  8701:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  8702:       /*
                   8703:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  8704:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   8705:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   8706:       }
1.187     brouard  8707:       cptcovage=0;
                   8708:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  8709:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  8710:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  8711:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   8712:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   8713:        /*scanf("%d",i);*/
                   8714:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   8715:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   8716:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   8717:            /* covar is not filled and then is empty */
                   8718:            cptcovprod--;
                   8719:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   8720:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   8721:            Typevar[k]=1;  /* 1 for age product */
                   8722:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   8723:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   8724:            /*printf("stre=%s ", stre);*/
                   8725:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   8726:            cptcovprod--;
                   8727:            cutl(stre,strb,strc,'V');
                   8728:            Tvar[k]=atoi(stre);
                   8729:            Typevar[k]=1;  /* 1 for age product */
                   8730:            cptcovage++;
                   8731:            Tage[cptcovage]=k;
                   8732:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   8733:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   8734:            cptcovn++;
                   8735:            cptcovprodnoage++;k1++;
                   8736:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   8737:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   8738:                                                because this model-covariate is a construction we invent a new column
                   8739:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   8740:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   8741:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   8742:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   8743:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   8744:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   8745:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   8746:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   8747:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   8748:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   8749:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   8750:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  8751:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  8752:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   8753:            for (i=1; i<=lastobs;i++){
                   8754:              /* Computes the new covariate which is a product of
                   8755:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   8756:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   8757:            }
                   8758:          } /* End age is not in the model */
                   8759:        } /* End if model includes a product */
                   8760:        else { /* no more sum */
                   8761:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   8762:          /*  scanf("%d",i);*/
                   8763:          cutl(strd,strc,strb,'V');
                   8764:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   8765:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   8766:          Tvar[k]=atoi(strd);
                   8767:          Typevar[k]=0;  /* 0 for simple covariates */
                   8768:        }
                   8769:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  8770:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  8771:                                  scanf("%d",i);*/
1.187     brouard  8772:       } /* end of loop + on total covariates */
                   8773:     } /* end if strlen(modelsave == 0) age*age might exist */
                   8774:   } /* end if strlen(model == 0) */
1.136     brouard  8775:   
                   8776:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   8777:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  8778:   
1.136     brouard  8779:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  8780:      printf("cptcovprod=%d ", cptcovprod);
                   8781:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   8782:      scanf("%d ",i);*/
                   8783: 
                   8784: 
1.230     brouard  8785: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   8786:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  8787: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   8788:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   8789:    k =           1    2   3     4       5       6      7      8        9
                   8790:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   8791:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  8792:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   8793:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   8794:          Tmodelind[combination of covar]=k;
1.225     brouard  8795: */  
                   8796: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  8797:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  8798:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  8799:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  8800:   printf("Model=%s\n\
                   8801: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8802: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8803: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8804:   fprintf(ficlog,"Model=%s\n\
                   8805: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8806: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8807: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  8808:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  8809:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   8810:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  8811:       Fixed[k]= 0;
                   8812:       Dummy[k]= 0;
1.225     brouard  8813:       ncoveff++;
1.232     brouard  8814:       ncovf++;
1.234     brouard  8815:       nsd++;
                   8816:       modell[k].maintype= FTYPE;
                   8817:       TvarsD[nsd]=Tvar[k];
                   8818:       TvarsDind[nsd]=k;
                   8819:       TvarF[ncovf]=Tvar[k];
                   8820:       TvarFind[ncovf]=k;
                   8821:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8822:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8823:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   8824:       Fixed[k]= 0;
                   8825:       Dummy[k]= 0;
                   8826:       ncoveff++;
                   8827:       ncovf++;
                   8828:       modell[k].maintype= FTYPE;
                   8829:       TvarF[ncovf]=Tvar[k];
                   8830:       TvarFind[ncovf]=k;
1.230     brouard  8831:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  8832:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  8833:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  8834:       Fixed[k]= 0;
                   8835:       Dummy[k]= 1;
1.230     brouard  8836:       nqfveff++;
1.234     brouard  8837:       modell[k].maintype= FTYPE;
                   8838:       modell[k].subtype= FQ;
                   8839:       nsq++;
                   8840:       TvarsQ[nsq]=Tvar[k];
                   8841:       TvarsQind[nsq]=k;
1.232     brouard  8842:       ncovf++;
1.234     brouard  8843:       TvarF[ncovf]=Tvar[k];
                   8844:       TvarFind[ncovf]=k;
1.231     brouard  8845:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  8846:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  8847:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  8848:       Fixed[k]= 1;
                   8849:       Dummy[k]= 0;
1.225     brouard  8850:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  8851:       modell[k].maintype= VTYPE;
                   8852:       modell[k].subtype= VD;
                   8853:       nsd++;
                   8854:       TvarsD[nsd]=Tvar[k];
                   8855:       TvarsDind[nsd]=k;
                   8856:       ncovv++; /* Only simple time varying variables */
                   8857:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8858:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8859:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   8860:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  8861:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   8862:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  8863:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  8864:       Fixed[k]= 1;
                   8865:       Dummy[k]= 1;
                   8866:       nqtveff++;
                   8867:       modell[k].maintype= VTYPE;
                   8868:       modell[k].subtype= VQ;
                   8869:       ncovv++; /* Only simple time varying variables */
                   8870:       nsq++;
                   8871:       TvarsQ[nsq]=Tvar[k];
                   8872:       TvarsQind[nsq]=k;
                   8873:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8874:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8875:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   8876:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  8877:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   8878:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   8879:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  8880:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  8881:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  8882:       ncova++;
                   8883:       TvarA[ncova]=Tvar[k];
                   8884:       TvarAind[ncova]=k;
1.231     brouard  8885:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  8886:        Fixed[k]= 2;
                   8887:        Dummy[k]= 2;
                   8888:        modell[k].maintype= ATYPE;
                   8889:        modell[k].subtype= APFD;
                   8890:        /* ncoveff++; */
1.227     brouard  8891:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  8892:        Fixed[k]= 2;
                   8893:        Dummy[k]= 3;
                   8894:        modell[k].maintype= ATYPE;
                   8895:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   8896:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  8897:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  8898:        Fixed[k]= 3;
                   8899:        Dummy[k]= 2;
                   8900:        modell[k].maintype= ATYPE;
                   8901:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   8902:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  8903:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  8904:        Fixed[k]= 3;
                   8905:        Dummy[k]= 3;
                   8906:        modell[k].maintype= ATYPE;
                   8907:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   8908:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  8909:       }
                   8910:     }else if (Typevar[k] == 2) {  /* product without age */
                   8911:       k1=Tposprod[k];
                   8912:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  8913:        if(Tvard[k1][2] <=ncovcol){
                   8914:          Fixed[k]= 1;
                   8915:          Dummy[k]= 0;
                   8916:          modell[k].maintype= FTYPE;
                   8917:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   8918:          ncovf++; /* Fixed variables without age */
                   8919:          TvarF[ncovf]=Tvar[k];
                   8920:          TvarFind[ncovf]=k;
                   8921:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8922:          Fixed[k]= 0;  /* or 2 ?*/
                   8923:          Dummy[k]= 1;
                   8924:          modell[k].maintype= FTYPE;
                   8925:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   8926:          ncovf++; /* Varying variables without age */
                   8927:          TvarF[ncovf]=Tvar[k];
                   8928:          TvarFind[ncovf]=k;
                   8929:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8930:          Fixed[k]= 1;
                   8931:          Dummy[k]= 0;
                   8932:          modell[k].maintype= VTYPE;
                   8933:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   8934:          ncovv++; /* Varying variables without age */
                   8935:          TvarV[ncovv]=Tvar[k];
                   8936:          TvarVind[ncovv]=k;
                   8937:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8938:          Fixed[k]= 1;
                   8939:          Dummy[k]= 1;
                   8940:          modell[k].maintype= VTYPE;
                   8941:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   8942:          ncovv++; /* Varying variables without age */
                   8943:          TvarV[ncovv]=Tvar[k];
                   8944:          TvarVind[ncovv]=k;
                   8945:        }
1.227     brouard  8946:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  8947:        if(Tvard[k1][2] <=ncovcol){
                   8948:          Fixed[k]= 0;  /* or 2 ?*/
                   8949:          Dummy[k]= 1;
                   8950:          modell[k].maintype= FTYPE;
                   8951:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   8952:          ncovf++; /* Fixed variables without age */
                   8953:          TvarF[ncovf]=Tvar[k];
                   8954:          TvarFind[ncovf]=k;
                   8955:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8956:          Fixed[k]= 1;
                   8957:          Dummy[k]= 1;
                   8958:          modell[k].maintype= VTYPE;
                   8959:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   8960:          ncovv++; /* Varying variables without age */
                   8961:          TvarV[ncovv]=Tvar[k];
                   8962:          TvarVind[ncovv]=k;
                   8963:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8964:          Fixed[k]= 1;
                   8965:          Dummy[k]= 1;
                   8966:          modell[k].maintype= VTYPE;
                   8967:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   8968:          ncovv++; /* Varying variables without age */
                   8969:          TvarV[ncovv]=Tvar[k];
                   8970:          TvarVind[ncovv]=k;
                   8971:          ncovv++; /* Varying variables without age */
                   8972:          TvarV[ncovv]=Tvar[k];
                   8973:          TvarVind[ncovv]=k;
                   8974:        }
1.227     brouard  8975:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  8976:        if(Tvard[k1][2] <=ncovcol){
                   8977:          Fixed[k]= 1;
                   8978:          Dummy[k]= 1;
                   8979:          modell[k].maintype= VTYPE;
                   8980:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   8981:          ncovv++; /* Varying variables without age */
                   8982:          TvarV[ncovv]=Tvar[k];
                   8983:          TvarVind[ncovv]=k;
                   8984:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8985:          Fixed[k]= 1;
                   8986:          Dummy[k]= 1;
                   8987:          modell[k].maintype= VTYPE;
                   8988:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   8989:          ncovv++; /* Varying variables without age */
                   8990:          TvarV[ncovv]=Tvar[k];
                   8991:          TvarVind[ncovv]=k;
                   8992:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8993:          Fixed[k]= 1;
                   8994:          Dummy[k]= 0;
                   8995:          modell[k].maintype= VTYPE;
                   8996:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   8997:          ncovv++; /* Varying variables without age */
                   8998:          TvarV[ncovv]=Tvar[k];
                   8999:          TvarVind[ncovv]=k;
                   9000:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9001:          Fixed[k]= 1;
                   9002:          Dummy[k]= 1;
                   9003:          modell[k].maintype= VTYPE;
                   9004:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9005:          ncovv++; /* Varying variables without age */
                   9006:          TvarV[ncovv]=Tvar[k];
                   9007:          TvarVind[ncovv]=k;
                   9008:        }
1.227     brouard  9009:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9010:        if(Tvard[k1][2] <=ncovcol){
                   9011:          Fixed[k]= 1;
                   9012:          Dummy[k]= 1;
                   9013:          modell[k].maintype= VTYPE;
                   9014:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9015:          ncovv++; /* Varying variables without age */
                   9016:          TvarV[ncovv]=Tvar[k];
                   9017:          TvarVind[ncovv]=k;
                   9018:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9019:          Fixed[k]= 1;
                   9020:          Dummy[k]= 1;
                   9021:          modell[k].maintype= VTYPE;
                   9022:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9023:          ncovv++; /* Varying variables without age */
                   9024:          TvarV[ncovv]=Tvar[k];
                   9025:          TvarVind[ncovv]=k;
                   9026:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9027:          Fixed[k]= 1;
                   9028:          Dummy[k]= 1;
                   9029:          modell[k].maintype= VTYPE;
                   9030:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9031:          ncovv++; /* Varying variables without age */
                   9032:          TvarV[ncovv]=Tvar[k];
                   9033:          TvarVind[ncovv]=k;
                   9034:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9035:          Fixed[k]= 1;
                   9036:          Dummy[k]= 1;
                   9037:          modell[k].maintype= VTYPE;
                   9038:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9039:          ncovv++; /* Varying variables without age */
                   9040:          TvarV[ncovv]=Tvar[k];
                   9041:          TvarVind[ncovv]=k;
                   9042:        }
1.227     brouard  9043:       }else{
1.240     brouard  9044:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9045:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9046:       } /*end k1*/
1.225     brouard  9047:     }else{
1.226     brouard  9048:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9049:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9050:     }
1.227     brouard  9051:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9052:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9053:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9054:   }
                   9055:   /* Searching for doublons in the model */
                   9056:   for(k1=1; k1<= cptcovt;k1++){
                   9057:     for(k2=1; k2 <k1;k2++){
                   9058:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  9059:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9060:          if(Tvar[k1]==Tvar[k2]){
                   9061:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9062:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9063:            return(1);
                   9064:          }
                   9065:        }else if (Typevar[k1] ==2){
                   9066:          k3=Tposprod[k1];
                   9067:          k4=Tposprod[k2];
                   9068:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   9069:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9070:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9071:            return(1);
                   9072:          }
                   9073:        }
1.227     brouard  9074:       }
                   9075:     }
1.225     brouard  9076:   }
                   9077:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   9078:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  9079:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   9080:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  9081:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  9082:   /*endread:*/
1.225     brouard  9083:   printf("Exiting decodemodel: ");
                   9084:   return (1);
1.136     brouard  9085: }
                   9086: 
1.169     brouard  9087: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  9088: {/* Check ages at death */
1.136     brouard  9089:   int i, m;
1.218     brouard  9090:   int firstone=0;
                   9091:   
1.136     brouard  9092:   for (i=1; i<=imx; i++) {
                   9093:     for(m=2; (m<= maxwav); m++) {
                   9094:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   9095:        anint[m][i]=9999;
1.216     brouard  9096:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   9097:          s[m][i]=-1;
1.136     brouard  9098:       }
                   9099:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.169     brouard  9100:        *nberr = *nberr + 1;
1.218     brouard  9101:        if(firstone == 0){
                   9102:          firstone=1;
                   9103:        printf("Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\nOther similar cases in log file\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
                   9104:        }
                   9105:        fprintf(ficlog,"Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
1.136     brouard  9106:        s[m][i]=-1;
                   9107:       }
                   9108:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  9109:        (*nberr)++;
1.136     brouard  9110:        printf("Error! Month of death of individual %ld on line %d was unknown %2d, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,(int)moisdc[i]); 
                   9111:        fprintf(ficlog,"Error! Month of death of individual %ld on line %d was unknown %f, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,moisdc[i]); 
                   9112:        s[m][i]=-1; /* We prefer to skip it (and to skip it in version 0.8a1 too */
                   9113:       }
                   9114:     }
                   9115:   }
                   9116: 
                   9117:   for (i=1; i<=imx; i++)  {
                   9118:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   9119:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  9120:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  9121:        if (s[m][i] >= nlstate+1) {
1.169     brouard  9122:          if(agedc[i]>0){
                   9123:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  9124:              agev[m][i]=agedc[i];
1.214     brouard  9125:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  9126:            }else {
1.136     brouard  9127:              if ((int)andc[i]!=9999){
                   9128:                nbwarn++;
                   9129:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   9130:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   9131:                agev[m][i]=-1;
                   9132:              }
                   9133:            }
1.169     brouard  9134:          } /* agedc > 0 */
1.214     brouard  9135:        } /* end if */
1.136     brouard  9136:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   9137:                                 years but with the precision of a month */
                   9138:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   9139:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   9140:            agev[m][i]=1;
                   9141:          else if(agev[m][i] < *agemin){ 
                   9142:            *agemin=agev[m][i];
                   9143:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   9144:          }
                   9145:          else if(agev[m][i] >*agemax){
                   9146:            *agemax=agev[m][i];
1.156     brouard  9147:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  9148:          }
                   9149:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   9150:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  9151:        } /* en if 9*/
1.136     brouard  9152:        else { /* =9 */
1.214     brouard  9153:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  9154:          agev[m][i]=1;
                   9155:          s[m][i]=-1;
                   9156:        }
                   9157:       }
1.214     brouard  9158:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  9159:        agev[m][i]=1;
1.214     brouard  9160:       else{
                   9161:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9162:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9163:        agev[m][i]=0;
                   9164:       }
                   9165:     } /* End for lastpass */
                   9166:   }
1.136     brouard  9167:     
                   9168:   for (i=1; i<=imx; i++)  {
                   9169:     for(m=firstpass; (m<=lastpass); m++){
                   9170:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  9171:        (*nberr)++;
1.136     brouard  9172:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9173:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9174:        return 1;
                   9175:       }
                   9176:     }
                   9177:   }
                   9178: 
                   9179:   /*for (i=1; i<=imx; i++){
                   9180:   for (m=firstpass; (m<lastpass); m++){
                   9181:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   9182: }
                   9183: 
                   9184: }*/
                   9185: 
                   9186: 
1.139     brouard  9187:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   9188:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  9189: 
                   9190:   return (0);
1.164     brouard  9191:  /* endread:*/
1.136     brouard  9192:     printf("Exiting calandcheckages: ");
                   9193:     return (1);
                   9194: }
                   9195: 
1.172     brouard  9196: #if defined(_MSC_VER)
                   9197: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9198: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9199: //#include "stdafx.h"
                   9200: //#include <stdio.h>
                   9201: //#include <tchar.h>
                   9202: //#include <windows.h>
                   9203: //#include <iostream>
                   9204: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   9205: 
                   9206: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9207: 
                   9208: BOOL IsWow64()
                   9209: {
                   9210:        BOOL bIsWow64 = FALSE;
                   9211: 
                   9212:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   9213:        //  (HANDLE, PBOOL);
                   9214: 
                   9215:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9216: 
                   9217:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   9218:        const char funcName[] = "IsWow64Process";
                   9219:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   9220:                GetProcAddress(module, funcName);
                   9221: 
                   9222:        if (NULL != fnIsWow64Process)
                   9223:        {
                   9224:                if (!fnIsWow64Process(GetCurrentProcess(),
                   9225:                        &bIsWow64))
                   9226:                        //throw std::exception("Unknown error");
                   9227:                        printf("Unknown error\n");
                   9228:        }
                   9229:        return bIsWow64 != FALSE;
                   9230: }
                   9231: #endif
1.177     brouard  9232: 
1.191     brouard  9233: void syscompilerinfo(int logged)
1.167     brouard  9234:  {
                   9235:    /* #include "syscompilerinfo.h"*/
1.185     brouard  9236:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   9237:    /* /GS /W3 /Gy
                   9238:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   9239:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   9240:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  9241:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   9242:    */ 
                   9243:    /* 64 bits */
1.185     brouard  9244:    /*
                   9245:      /GS /W3 /Gy
                   9246:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   9247:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   9248:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   9249:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   9250:    /* Optimization are useless and O3 is slower than O2 */
                   9251:    /*
                   9252:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   9253:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   9254:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   9255:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   9256:    */
1.186     brouard  9257:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  9258:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   9259:       /PDB:"visual studio
                   9260:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   9261:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   9262:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   9263:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   9264:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   9265:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   9266:       uiAccess='false'"
                   9267:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   9268:       /NOLOGO /TLBID:1
                   9269:    */
1.177     brouard  9270: #if defined __INTEL_COMPILER
1.178     brouard  9271: #if defined(__GNUC__)
                   9272:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   9273: #endif
1.177     brouard  9274: #elif defined(__GNUC__) 
1.179     brouard  9275: #ifndef  __APPLE__
1.174     brouard  9276: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  9277: #endif
1.177     brouard  9278:    struct utsname sysInfo;
1.178     brouard  9279:    int cross = CROSS;
                   9280:    if (cross){
                   9281:           printf("Cross-");
1.191     brouard  9282:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  9283:    }
1.174     brouard  9284: #endif
                   9285: 
1.171     brouard  9286: #include <stdint.h>
1.178     brouard  9287: 
1.191     brouard  9288:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  9289: #if defined(__clang__)
1.191     brouard  9290:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  9291: #endif
                   9292: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  9293:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  9294: #endif
                   9295: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  9296:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  9297: #endif
                   9298: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  9299:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  9300: #endif
                   9301: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  9302:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  9303: #endif
                   9304: #if defined(_MSC_VER)
1.191     brouard  9305:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  9306: #endif
                   9307: #if defined(__PGI)
1.191     brouard  9308:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  9309: #endif
                   9310: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  9311:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  9312: #endif
1.191     brouard  9313:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  9314:    
1.167     brouard  9315: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   9316: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   9317:     // Windows (x64 and x86)
1.191     brouard  9318:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  9319: #elif __unix__ // all unices, not all compilers
                   9320:     // Unix
1.191     brouard  9321:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  9322: #elif __linux__
                   9323:     // linux
1.191     brouard  9324:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  9325: #elif __APPLE__
1.174     brouard  9326:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  9327:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  9328: #endif
                   9329: 
                   9330: /*  __MINGW32__          */
                   9331: /*  __CYGWIN__  */
                   9332: /* __MINGW64__  */
                   9333: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   9334: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   9335: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   9336: /* _WIN64  // Defined for applications for Win64. */
                   9337: /* _M_X64 // Defined for compilations that target x64 processors. */
                   9338: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  9339: 
1.167     brouard  9340: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  9341:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  9342: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  9343:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  9344: #else
1.191     brouard  9345:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  9346: #endif
                   9347: 
1.169     brouard  9348: #if defined(__GNUC__)
                   9349: # if defined(__GNUC_PATCHLEVEL__)
                   9350: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9351:                             + __GNUC_MINOR__ * 100 \
                   9352:                             + __GNUC_PATCHLEVEL__)
                   9353: # else
                   9354: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9355:                             + __GNUC_MINOR__ * 100)
                   9356: # endif
1.174     brouard  9357:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  9358:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  9359: 
                   9360:    if (uname(&sysInfo) != -1) {
                   9361:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  9362:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  9363:    }
                   9364:    else
                   9365:       perror("uname() error");
1.179     brouard  9366:    //#ifndef __INTEL_COMPILER 
                   9367: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  9368:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  9369:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  9370: #endif
1.169     brouard  9371: #endif
1.172     brouard  9372: 
                   9373:    //   void main()
                   9374:    //   {
1.169     brouard  9375: #if defined(_MSC_VER)
1.174     brouard  9376:    if (IsWow64()){
1.191     brouard  9377:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   9378:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  9379:    }
                   9380:    else{
1.191     brouard  9381:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   9382:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  9383:    }
1.172     brouard  9384:    //     printf("\nPress Enter to continue...");
                   9385:    //     getchar();
                   9386:    //   }
                   9387: 
1.169     brouard  9388: #endif
                   9389:    
1.167     brouard  9390: 
1.219     brouard  9391: }
1.136     brouard  9392: 
1.219     brouard  9393: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  9394:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  9395:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  9396:   /* double ftolpl = 1.e-10; */
1.180     brouard  9397:   double age, agebase, agelim;
1.203     brouard  9398:   double tot;
1.180     brouard  9399: 
1.202     brouard  9400:   strcpy(filerespl,"PL_");
                   9401:   strcat(filerespl,fileresu);
                   9402:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   9403:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9404:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9405:   }
1.227     brouard  9406:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   9407:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  9408:   pstamp(ficrespl);
1.203     brouard  9409:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  9410:   fprintf(ficrespl,"#Age ");
                   9411:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   9412:   fprintf(ficrespl,"\n");
1.180     brouard  9413:   
1.219     brouard  9414:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  9415: 
1.219     brouard  9416:   agebase=ageminpar;
                   9417:   agelim=agemaxpar;
1.180     brouard  9418: 
1.227     brouard  9419:   /* i1=pow(2,ncoveff); */
1.234     brouard  9420:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  9421:   if (cptcovn < 1){i1=1;}
1.180     brouard  9422: 
1.238     brouard  9423:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   9424:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  9425:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9426:        continue;
1.235     brouard  9427: 
1.238     brouard  9428:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9429:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   9430:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   9431:       /* k=k+1; */
                   9432:       /* to clean */
                   9433:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9434:       fprintf(ficrespl,"#******");
                   9435:       printf("#******");
                   9436:       fprintf(ficlog,"#******");
                   9437:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9438:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   9439:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9440:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9441:       }
                   9442:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9443:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9444:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9445:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9446:       }
                   9447:       fprintf(ficrespl,"******\n");
                   9448:       printf("******\n");
                   9449:       fprintf(ficlog,"******\n");
                   9450:       if(invalidvarcomb[k]){
                   9451:        printf("\nCombination (%d) ignored because no case \n",k); 
                   9452:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   9453:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   9454:        continue;
                   9455:       }
1.219     brouard  9456: 
1.238     brouard  9457:       fprintf(ficrespl,"#Age ");
                   9458:       for(j=1;j<=cptcoveff;j++) {
                   9459:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9460:       }
                   9461:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   9462:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  9463:     
1.238     brouard  9464:       for (age=agebase; age<=agelim; age++){
                   9465:        /* for (age=agebase; age<=agebase; age++){ */
                   9466:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   9467:        fprintf(ficrespl,"%.0f ",age );
                   9468:        for(j=1;j<=cptcoveff;j++)
                   9469:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9470:        tot=0.;
                   9471:        for(i=1; i<=nlstate;i++){
                   9472:          tot +=  prlim[i][i];
                   9473:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   9474:        }
                   9475:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   9476:       } /* Age */
                   9477:       /* was end of cptcod */
                   9478:     } /* cptcov */
                   9479:   } /* nres */
1.219     brouard  9480:   return 0;
1.180     brouard  9481: }
                   9482: 
1.218     brouard  9483: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   9484:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   9485:        
                   9486:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   9487:    * at any age between ageminpar and agemaxpar
                   9488:         */
1.235     brouard  9489:   int i, j, k, i1, nres=0 ;
1.217     brouard  9490:   /* double ftolpl = 1.e-10; */
                   9491:   double age, agebase, agelim;
                   9492:   double tot;
1.218     brouard  9493:   /* double ***mobaverage; */
                   9494:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  9495: 
                   9496:   strcpy(fileresplb,"PLB_");
                   9497:   strcat(fileresplb,fileresu);
                   9498:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   9499:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9500:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9501:   }
                   9502:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9503:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9504:   pstamp(ficresplb);
                   9505:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   9506:   fprintf(ficresplb,"#Age ");
                   9507:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   9508:   fprintf(ficresplb,"\n");
                   9509:   
1.218     brouard  9510:   
                   9511:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   9512:   
                   9513:   agebase=ageminpar;
                   9514:   agelim=agemaxpar;
                   9515:   
                   9516:   
1.227     brouard  9517:   i1=pow(2,cptcoveff);
1.218     brouard  9518:   if (cptcovn < 1){i1=1;}
1.227     brouard  9519:   
1.238     brouard  9520:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9521:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  9522:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9523:        continue;
                   9524:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9525:       fprintf(ficresplb,"#******");
                   9526:       printf("#******");
                   9527:       fprintf(ficlog,"#******");
                   9528:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9529:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9530:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9531:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9532:       }
                   9533:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9534:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9535:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9536:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9537:       }
                   9538:       fprintf(ficresplb,"******\n");
                   9539:       printf("******\n");
                   9540:       fprintf(ficlog,"******\n");
                   9541:       if(invalidvarcomb[k]){
                   9542:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   9543:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   9544:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   9545:        continue;
                   9546:       }
1.218     brouard  9547:     
1.238     brouard  9548:       fprintf(ficresplb,"#Age ");
                   9549:       for(j=1;j<=cptcoveff;j++) {
                   9550:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9551:       }
                   9552:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   9553:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  9554:     
                   9555:     
1.238     brouard  9556:       for (age=agebase; age<=agelim; age++){
                   9557:        /* for (age=agebase; age<=agebase; age++){ */
                   9558:        if(mobilavproj > 0){
                   9559:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   9560:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9561:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  9562:        }else if (mobilavproj == 0){
                   9563:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9564:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9565:          exit(1);
                   9566:        }else{
                   9567:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9568:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.238     brouard  9569:        }
                   9570:        fprintf(ficresplb,"%.0f ",age );
                   9571:        for(j=1;j<=cptcoveff;j++)
                   9572:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9573:        tot=0.;
                   9574:        for(i=1; i<=nlstate;i++){
                   9575:          tot +=  bprlim[i][i];
                   9576:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   9577:        }
                   9578:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   9579:       } /* Age */
                   9580:       /* was end of cptcod */
1.255     brouard  9581:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  9582:     } /* end of any combination */
                   9583:   } /* end of nres */  
1.218     brouard  9584:   /* hBijx(p, bage, fage); */
                   9585:   /* fclose(ficrespijb); */
                   9586:   
                   9587:   return 0;
1.217     brouard  9588: }
1.218     brouard  9589:  
1.180     brouard  9590: int hPijx(double *p, int bage, int fage){
                   9591:     /*------------- h Pij x at various ages ------------*/
                   9592: 
                   9593:   int stepsize;
                   9594:   int agelim;
                   9595:   int hstepm;
                   9596:   int nhstepm;
1.235     brouard  9597:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  9598: 
                   9599:   double agedeb;
                   9600:   double ***p3mat;
                   9601: 
1.201     brouard  9602:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  9603:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   9604:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9605:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9606:     }
                   9607:     printf("Computing pij: result on file '%s' \n", filerespij);
                   9608:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   9609:   
                   9610:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9611:     /*if (stepm<=24) stepsize=2;*/
                   9612: 
                   9613:     agelim=AGESUP;
                   9614:     hstepm=stepsize*YEARM; /* Every year of age */
                   9615:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  9616:                
1.180     brouard  9617:     /* hstepm=1;   aff par mois*/
                   9618:     pstamp(ficrespij);
                   9619:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  9620:     i1= pow(2,cptcoveff);
1.218     brouard  9621:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9622:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9623:                /*      k=k+1;  */
1.235     brouard  9624:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9625:     for(k=1; k<=i1;k++){
1.253     brouard  9626:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  9627:        continue;
1.183     brouard  9628:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  9629:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  9630:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  9631:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9632:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9633:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9634:       }
1.183     brouard  9635:       fprintf(ficrespij,"******\n");
                   9636:       
                   9637:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   9638:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   9639:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   9640:        
                   9641:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  9642:        
1.183     brouard  9643:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9644:        oldm=oldms;savm=savms;
1.235     brouard  9645:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  9646:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   9647:        for(i=1; i<=nlstate;i++)
                   9648:          for(j=1; j<=nlstate+ndeath;j++)
                   9649:            fprintf(ficrespij," %1d-%1d",i,j);
                   9650:        fprintf(ficrespij,"\n");
                   9651:        for (h=0; h<=nhstepm; h++){
                   9652:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9653:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  9654:          for(i=1; i<=nlstate;i++)
                   9655:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  9656:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  9657:          fprintf(ficrespij,"\n");
                   9658:        }
1.183     brouard  9659:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9660:        fprintf(ficrespij,"\n");
                   9661:       }
1.180     brouard  9662:       /*}*/
                   9663:     }
1.218     brouard  9664:     return 0;
1.180     brouard  9665: }
1.218     brouard  9666:  
                   9667:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  9668:     /*------------- h Bij x at various ages ------------*/
                   9669: 
                   9670:   int stepsize;
1.218     brouard  9671:   /* int agelim; */
                   9672:        int ageminl;
1.217     brouard  9673:   int hstepm;
                   9674:   int nhstepm;
1.238     brouard  9675:   int h, i, i1, j, k, nres;
1.218     brouard  9676:        
1.217     brouard  9677:   double agedeb;
                   9678:   double ***p3mat;
1.218     brouard  9679:        
                   9680:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   9681:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   9682:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9683:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9684:   }
                   9685:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   9686:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   9687:   
                   9688:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9689:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  9690:   
1.218     brouard  9691:   /* agelim=AGESUP; */
                   9692:   ageminl=30;
                   9693:   hstepm=stepsize*YEARM; /* Every year of age */
                   9694:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   9695:   
                   9696:   /* hstepm=1;   aff par mois*/
                   9697:   pstamp(ficrespijb);
1.255     brouard  9698:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  9699:   i1= pow(2,cptcoveff);
1.218     brouard  9700:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9701:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9702:   /*   k=k+1;  */
1.238     brouard  9703:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9704:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  9705:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9706:        continue;
                   9707:       fprintf(ficrespijb,"\n#****** ");
                   9708:       for(j=1;j<=cptcoveff;j++)
                   9709:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9710:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9711:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9712:       }
                   9713:       fprintf(ficrespijb,"******\n");
                   9714:       if(invalidvarcomb[k]){
                   9715:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   9716:        continue;
                   9717:       }
                   9718:       
                   9719:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   9720:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   9721:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   9722:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   9723:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   9724:        
                   9725:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   9726:        
                   9727:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9728:        /* oldm=oldms;savm=savms; */
                   9729:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9730:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k);
                   9731:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  9732:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  9733:        for(i=1; i<=nlstate;i++)
                   9734:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  9735:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  9736:        fprintf(ficrespijb,"\n");
1.238     brouard  9737:        for (h=0; h<=nhstepm; h++){
                   9738:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9739:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   9740:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   9741:          for(i=1; i<=nlstate;i++)
                   9742:            for(j=1; j<=nlstate+ndeath;j++)
                   9743:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   9744:          fprintf(ficrespijb,"\n");
                   9745:        }
                   9746:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9747:        fprintf(ficrespijb,"\n");
                   9748:       } /* end age deb */
                   9749:     } /* end combination */
                   9750:   } /* end nres */
1.218     brouard  9751:   return 0;
                   9752:  } /*  hBijx */
1.217     brouard  9753: 
1.180     brouard  9754: 
1.136     brouard  9755: /***********************************************/
                   9756: /**************** Main Program *****************/
                   9757: /***********************************************/
                   9758: 
                   9759: int main(int argc, char *argv[])
                   9760: {
                   9761: #ifdef GSL
                   9762:   const gsl_multimin_fminimizer_type *T;
                   9763:   size_t iteri = 0, it;
                   9764:   int rval = GSL_CONTINUE;
                   9765:   int status = GSL_SUCCESS;
                   9766:   double ssval;
                   9767: #endif
                   9768:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  9769:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  9770:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  9771:   int jj, ll, li, lj, lk;
1.136     brouard  9772:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  9773:   int num_filled;
1.136     brouard  9774:   int itimes;
                   9775:   int NDIM=2;
                   9776:   int vpopbased=0;
1.235     brouard  9777:   int nres=0;
1.136     brouard  9778: 
1.164     brouard  9779:   char ca[32], cb[32];
1.136     brouard  9780:   /*  FILE *fichtm; *//* Html File */
                   9781:   /* FILE *ficgp;*/ /*Gnuplot File */
                   9782:   struct stat info;
1.191     brouard  9783:   double agedeb=0.;
1.194     brouard  9784: 
                   9785:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  9786:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  9787: 
1.165     brouard  9788:   double fret;
1.191     brouard  9789:   double dum=0.; /* Dummy variable */
1.136     brouard  9790:   double ***p3mat;
1.218     brouard  9791:   /* double ***mobaverage; */
1.164     brouard  9792: 
                   9793:   char line[MAXLINE];
1.197     brouard  9794:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   9795: 
1.234     brouard  9796:   char  modeltemp[MAXLINE];
1.230     brouard  9797:   char resultline[MAXLINE];
                   9798:   
1.136     brouard  9799:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  9800:   char *tok, *val; /* pathtot */
1.136     brouard  9801:   int firstobs=1, lastobs=10;
1.195     brouard  9802:   int c,  h , cpt, c2;
1.191     brouard  9803:   int jl=0;
                   9804:   int i1, j1, jk, stepsize=0;
1.194     brouard  9805:   int count=0;
                   9806: 
1.164     brouard  9807:   int *tab; 
1.136     brouard  9808:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  9809:   int backcast=0;
1.136     brouard  9810:   int mobilav=0,popforecast=0;
1.191     brouard  9811:   int hstepm=0, nhstepm=0;
1.136     brouard  9812:   int agemortsup;
                   9813:   float  sumlpop=0.;
                   9814:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   9815:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   9816: 
1.191     brouard  9817:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  9818:   double ftolpl=FTOL;
                   9819:   double **prlim;
1.217     brouard  9820:   double **bprlim;
1.136     brouard  9821:   double ***param; /* Matrix of parameters */
1.251     brouard  9822:   double ***paramstart; /* Matrix of starting parameter values */
                   9823:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  9824:   double **matcov; /* Matrix of covariance */
1.203     brouard  9825:   double **hess; /* Hessian matrix */
1.136     brouard  9826:   double ***delti3; /* Scale */
                   9827:   double *delti; /* Scale */
                   9828:   double ***eij, ***vareij;
                   9829:   double **varpl; /* Variances of prevalence limits by age */
                   9830:   double *epj, vepp;
1.164     brouard  9831: 
1.136     brouard  9832:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  9833:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   9834: 
1.136     brouard  9835:   double **ximort;
1.145     brouard  9836:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  9837:   int *dcwave;
                   9838: 
1.164     brouard  9839:   char z[1]="c";
1.136     brouard  9840: 
                   9841:   /*char  *strt;*/
                   9842:   char strtend[80];
1.126     brouard  9843: 
1.164     brouard  9844: 
1.126     brouard  9845: /*   setlocale (LC_ALL, ""); */
                   9846: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   9847: /*   textdomain (PACKAGE); */
                   9848: /*   setlocale (LC_CTYPE, ""); */
                   9849: /*   setlocale (LC_MESSAGES, ""); */
                   9850: 
                   9851:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  9852:   rstart_time = time(NULL);  
                   9853:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   9854:   start_time = *localtime(&rstart_time);
1.126     brouard  9855:   curr_time=start_time;
1.157     brouard  9856:   /*tml = *localtime(&start_time.tm_sec);*/
                   9857:   /* strcpy(strstart,asctime(&tml)); */
                   9858:   strcpy(strstart,asctime(&start_time));
1.126     brouard  9859: 
                   9860: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  9861: /*  tp.tm_sec = tp.tm_sec +86400; */
                   9862: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  9863: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   9864: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   9865: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  9866: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  9867: /*   strt=asctime(&tmg); */
                   9868: /*   printf("Time(after) =%s",strstart);  */
                   9869: /*  (void) time (&time_value);
                   9870: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   9871: *  tm = *localtime(&time_value);
                   9872: *  strstart=asctime(&tm);
                   9873: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   9874: */
                   9875: 
                   9876:   nberr=0; /* Number of errors and warnings */
                   9877:   nbwarn=0;
1.184     brouard  9878: #ifdef WIN32
                   9879:   _getcwd(pathcd, size);
                   9880: #else
1.126     brouard  9881:   getcwd(pathcd, size);
1.184     brouard  9882: #endif
1.191     brouard  9883:   syscompilerinfo(0);
1.196     brouard  9884:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  9885:   if(argc <=1){
                   9886:     printf("\nEnter the parameter file name: ");
1.205     brouard  9887:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   9888:       printf("ERROR Empty parameter file name\n");
                   9889:       goto end;
                   9890:     }
1.126     brouard  9891:     i=strlen(pathr);
                   9892:     if(pathr[i-1]=='\n')
                   9893:       pathr[i-1]='\0';
1.156     brouard  9894:     i=strlen(pathr);
1.205     brouard  9895:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  9896:       pathr[i-1]='\0';
1.205     brouard  9897:     }
                   9898:     i=strlen(pathr);
                   9899:     if( i==0 ){
                   9900:       printf("ERROR Empty parameter file name\n");
                   9901:       goto end;
                   9902:     }
                   9903:     for (tok = pathr; tok != NULL; ){
1.126     brouard  9904:       printf("Pathr |%s|\n",pathr);
                   9905:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   9906:       printf("val= |%s| pathr=%s\n",val,pathr);
                   9907:       strcpy (pathtot, val);
                   9908:       if(pathr[0] == '\0') break; /* Dirty */
                   9909:     }
                   9910:   }
                   9911:   else{
                   9912:     strcpy(pathtot,argv[1]);
                   9913:   }
                   9914:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   9915:   /*cygwin_split_path(pathtot,path,optionfile);
                   9916:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   9917:   /* cutv(path,optionfile,pathtot,'\\');*/
                   9918: 
                   9919:   /* Split argv[0], imach program to get pathimach */
                   9920:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   9921:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9922:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9923:  /*   strcpy(pathimach,argv[0]); */
                   9924:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   9925:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   9926:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  9927: #ifdef WIN32
                   9928:   _chdir(path); /* Can be a relative path */
                   9929:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   9930: #else
1.126     brouard  9931:   chdir(path); /* Can be a relative path */
1.184     brouard  9932:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   9933: #endif
                   9934:   printf("Current directory %s!\n",pathcd);
1.126     brouard  9935:   strcpy(command,"mkdir ");
                   9936:   strcat(command,optionfilefiname);
                   9937:   if((outcmd=system(command)) != 0){
1.169     brouard  9938:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  9939:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   9940:     /* fclose(ficlog); */
                   9941: /*     exit(1); */
                   9942:   }
                   9943: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   9944: /*     perror("mkdir"); */
                   9945: /*   } */
                   9946: 
                   9947:   /*-------- arguments in the command line --------*/
                   9948: 
1.186     brouard  9949:   /* Main Log file */
1.126     brouard  9950:   strcat(filelog, optionfilefiname);
                   9951:   strcat(filelog,".log");    /* */
                   9952:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   9953:     printf("Problem with logfile %s\n",filelog);
                   9954:     goto end;
                   9955:   }
                   9956:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  9957:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  9958:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   9959:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   9960:  path=%s \n\
                   9961:  optionfile=%s\n\
                   9962:  optionfilext=%s\n\
1.156     brouard  9963:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  9964: 
1.197     brouard  9965:   syscompilerinfo(1);
1.167     brouard  9966: 
1.126     brouard  9967:   printf("Local time (at start):%s",strstart);
                   9968:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   9969:   fflush(ficlog);
                   9970: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  9971: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  9972: 
                   9973:   /* */
                   9974:   strcpy(fileres,"r");
                   9975:   strcat(fileres, optionfilefiname);
1.201     brouard  9976:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  9977:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  9978:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  9979: 
1.186     brouard  9980:   /* Main ---------arguments file --------*/
1.126     brouard  9981: 
                   9982:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  9983:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   9984:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  9985:     fflush(ficlog);
1.149     brouard  9986:     /* goto end; */
                   9987:     exit(70); 
1.126     brouard  9988:   }
                   9989: 
                   9990: 
                   9991: 
                   9992:   strcpy(filereso,"o");
1.201     brouard  9993:   strcat(filereso,fileresu);
1.126     brouard  9994:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   9995:     printf("Problem with Output resultfile: %s\n", filereso);
                   9996:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   9997:     fflush(ficlog);
                   9998:     goto end;
                   9999:   }
                   10000: 
                   10001:   /* Reads comments: lines beginning with '#' */
                   10002:   numlinepar=0;
1.197     brouard  10003: 
                   10004:     /* First parameter line */
                   10005:   while(fgets(line, MAXLINE, ficpar)) {
                   10006:     /* If line starts with a # it is a comment */
                   10007:     if (line[0] == '#') {
                   10008:       numlinepar++;
                   10009:       fputs(line,stdout);
                   10010:       fputs(line,ficparo);
                   10011:       fputs(line,ficlog);
                   10012:       continue;
                   10013:     }else
                   10014:       break;
                   10015:   }
                   10016:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   10017:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   10018:     if (num_filled != 5) {
                   10019:       printf("Should be 5 parameters\n");
                   10020:     }
1.126     brouard  10021:     numlinepar++;
1.197     brouard  10022:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   10023:   }
                   10024:   /* Second parameter line */
                   10025:   while(fgets(line, MAXLINE, ficpar)) {
                   10026:     /* If line starts with a # it is a comment */
                   10027:     if (line[0] == '#') {
                   10028:       numlinepar++;
                   10029:       fputs(line,stdout);
                   10030:       fputs(line,ficparo);
                   10031:       fputs(line,ficlog);
                   10032:       continue;
                   10033:     }else
                   10034:       break;
                   10035:   }
1.223     brouard  10036:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   10037:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   10038:     if (num_filled != 11) {
                   10039:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  10040:       printf("but line=%s\n",line);
1.197     brouard  10041:     }
1.223     brouard  10042:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  10043:   }
1.203     brouard  10044:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  10045:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  10046:   /* Third parameter line */
                   10047:   while(fgets(line, MAXLINE, ficpar)) {
                   10048:     /* If line starts with a # it is a comment */
                   10049:     if (line[0] == '#') {
                   10050:       numlinepar++;
                   10051:       fputs(line,stdout);
                   10052:       fputs(line,ficparo);
                   10053:       fputs(line,ficlog);
                   10054:       continue;
                   10055:     }else
                   10056:       break;
                   10057:   }
1.201     brouard  10058:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
                   10059:     if (num_filled == 0)
                   10060:             model[0]='\0';
                   10061:     else if (num_filled != 1){
1.197     brouard  10062:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10063:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10064:       model[0]='\0';
                   10065:       goto end;
                   10066:     }
                   10067:     else{
                   10068:       if (model[0]=='+'){
                   10069:        for(i=1; i<=strlen(model);i++)
                   10070:          modeltemp[i-1]=model[i];
1.201     brouard  10071:        strcpy(model,modeltemp); 
1.197     brouard  10072:       }
                   10073:     }
1.199     brouard  10074:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  10075:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  10076:   }
                   10077:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   10078:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   10079:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  10080:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   10081:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  10082:   fflush(ficlog);
1.190     brouard  10083:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   10084:   if(model[0]=='#'){
1.187     brouard  10085:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   10086:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   10087:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   10088:     if(mle != -1){
                   10089:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   10090:       exit(1);
                   10091:     }
                   10092:   }
1.126     brouard  10093:   while((c=getc(ficpar))=='#' && c!= EOF){
                   10094:     ungetc(c,ficpar);
                   10095:     fgets(line, MAXLINE, ficpar);
                   10096:     numlinepar++;
1.195     brouard  10097:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   10098:       z[0]=line[1];
                   10099:     }
                   10100:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  10101:     fputs(line, stdout);
                   10102:     //puts(line);
1.126     brouard  10103:     fputs(line,ficparo);
                   10104:     fputs(line,ficlog);
                   10105:   }
                   10106:   ungetc(c,ficpar);
                   10107: 
                   10108:    
1.145     brouard  10109:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.225     brouard  10110:   coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
1.233     brouard  10111:   cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.225     brouard  10112:   cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
1.136     brouard  10113:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   10114:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   10115:      v1+v2*age+v2*v3 makes cptcovn = 3
                   10116:   */
                   10117:   if (strlen(model)>1) 
1.187     brouard  10118:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  10119:   else
1.187     brouard  10120:     ncovmodel=2; /* Constant and age */
1.133     brouard  10121:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   10122:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  10123:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   10124:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10125:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10126:     fflush(stdout);
                   10127:     fclose (ficlog);
                   10128:     goto end;
                   10129:   }
1.126     brouard  10130:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10131:   delti=delti3[1][1];
                   10132:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   10133:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  10134: /* We could also provide initial parameters values giving by simple logistic regression 
                   10135:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   10136:       /* for(i=1;i<nlstate;i++){ */
                   10137:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10138:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10139:       /* } */
1.126     brouard  10140:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  10141:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   10142:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10143:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   10144:     fclose (ficparo);
                   10145:     fclose (ficlog);
                   10146:     goto end;
                   10147:     exit(0);
1.220     brouard  10148:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  10149:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  10150:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   10151:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10152:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10153:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10154:     hess=matrix(1,npar,1,npar);
1.220     brouard  10155:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  10156:     /* Read guessed parameters */
1.126     brouard  10157:     /* Reads comments: lines beginning with '#' */
                   10158:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10159:       ungetc(c,ficpar);
                   10160:       fgets(line, MAXLINE, ficpar);
                   10161:       numlinepar++;
1.141     brouard  10162:       fputs(line,stdout);
1.126     brouard  10163:       fputs(line,ficparo);
                   10164:       fputs(line,ficlog);
                   10165:     }
                   10166:     ungetc(c,ficpar);
                   10167:     
                   10168:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  10169:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  10170:     for(i=1; i <=nlstate; i++){
1.234     brouard  10171:       j=0;
1.126     brouard  10172:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  10173:        if(jj==i) continue;
                   10174:        j++;
                   10175:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10176:        if ((i1 != i) || (j1 != jj)){
                   10177:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  10178: It might be a problem of design; if ncovcol and the model are correct\n \
                   10179: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  10180:          exit(1);
                   10181:        }
                   10182:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10183:        if(mle==1)
                   10184:          printf("%1d%1d",i,jj);
                   10185:        fprintf(ficlog,"%1d%1d",i,jj);
                   10186:        for(k=1; k<=ncovmodel;k++){
                   10187:          fscanf(ficpar," %lf",&param[i][j][k]);
                   10188:          if(mle==1){
                   10189:            printf(" %lf",param[i][j][k]);
                   10190:            fprintf(ficlog," %lf",param[i][j][k]);
                   10191:          }
                   10192:          else
                   10193:            fprintf(ficlog," %lf",param[i][j][k]);
                   10194:          fprintf(ficparo," %lf",param[i][j][k]);
                   10195:        }
                   10196:        fscanf(ficpar,"\n");
                   10197:        numlinepar++;
                   10198:        if(mle==1)
                   10199:          printf("\n");
                   10200:        fprintf(ficlog,"\n");
                   10201:        fprintf(ficparo,"\n");
1.126     brouard  10202:       }
                   10203:     }  
                   10204:     fflush(ficlog);
1.234     brouard  10205:     
1.251     brouard  10206:     /* Reads parameters values */
1.126     brouard  10207:     p=param[1][1];
1.251     brouard  10208:     pstart=paramstart[1][1];
1.126     brouard  10209:     
                   10210:     /* Reads comments: lines beginning with '#' */
                   10211:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10212:       ungetc(c,ficpar);
                   10213:       fgets(line, MAXLINE, ficpar);
                   10214:       numlinepar++;
1.141     brouard  10215:       fputs(line,stdout);
1.126     brouard  10216:       fputs(line,ficparo);
                   10217:       fputs(line,ficlog);
                   10218:     }
                   10219:     ungetc(c,ficpar);
                   10220: 
                   10221:     for(i=1; i <=nlstate; i++){
                   10222:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  10223:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10224:        if ( (i1-i) * (j1-j) != 0){
                   10225:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   10226:          exit(1);
                   10227:        }
                   10228:        printf("%1d%1d",i,j);
                   10229:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10230:        fprintf(ficlog,"%1d%1d",i1,j1);
                   10231:        for(k=1; k<=ncovmodel;k++){
                   10232:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   10233:          printf(" %le",delti3[i][j][k]);
                   10234:          fprintf(ficparo," %le",delti3[i][j][k]);
                   10235:          fprintf(ficlog," %le",delti3[i][j][k]);
                   10236:        }
                   10237:        fscanf(ficpar,"\n");
                   10238:        numlinepar++;
                   10239:        printf("\n");
                   10240:        fprintf(ficparo,"\n");
                   10241:        fprintf(ficlog,"\n");
1.126     brouard  10242:       }
                   10243:     }
                   10244:     fflush(ficlog);
1.234     brouard  10245:     
1.145     brouard  10246:     /* Reads covariance matrix */
1.126     brouard  10247:     delti=delti3[1][1];
1.220     brouard  10248:                
                   10249:                
1.126     brouard  10250:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  10251:                
1.126     brouard  10252:     /* Reads comments: lines beginning with '#' */
                   10253:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10254:       ungetc(c,ficpar);
                   10255:       fgets(line, MAXLINE, ficpar);
                   10256:       numlinepar++;
1.141     brouard  10257:       fputs(line,stdout);
1.126     brouard  10258:       fputs(line,ficparo);
                   10259:       fputs(line,ficlog);
                   10260:     }
                   10261:     ungetc(c,ficpar);
1.220     brouard  10262:                
1.126     brouard  10263:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10264:     hess=matrix(1,npar,1,npar);
1.131     brouard  10265:     for(i=1; i <=npar; i++)
                   10266:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  10267:                
1.194     brouard  10268:     /* Scans npar lines */
1.126     brouard  10269:     for(i=1; i <=npar; i++){
1.226     brouard  10270:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  10271:       if(count != 3){
1.226     brouard  10272:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10273: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10274: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10275:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10276: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10277: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10278:        exit(1);
1.220     brouard  10279:       }else{
1.226     brouard  10280:        if(mle==1)
                   10281:          printf("%1d%1d%d",i1,j1,jk);
                   10282:       }
                   10283:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   10284:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  10285:       for(j=1; j <=i; j++){
1.226     brouard  10286:        fscanf(ficpar," %le",&matcov[i][j]);
                   10287:        if(mle==1){
                   10288:          printf(" %.5le",matcov[i][j]);
                   10289:        }
                   10290:        fprintf(ficlog," %.5le",matcov[i][j]);
                   10291:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  10292:       }
                   10293:       fscanf(ficpar,"\n");
                   10294:       numlinepar++;
                   10295:       if(mle==1)
1.220     brouard  10296:                                printf("\n");
1.126     brouard  10297:       fprintf(ficlog,"\n");
                   10298:       fprintf(ficparo,"\n");
                   10299:     }
1.194     brouard  10300:     /* End of read covariance matrix npar lines */
1.126     brouard  10301:     for(i=1; i <=npar; i++)
                   10302:       for(j=i+1;j<=npar;j++)
1.226     brouard  10303:        matcov[i][j]=matcov[j][i];
1.126     brouard  10304:     
                   10305:     if(mle==1)
                   10306:       printf("\n");
                   10307:     fprintf(ficlog,"\n");
                   10308:     
                   10309:     fflush(ficlog);
                   10310:     
                   10311:     /*-------- Rewriting parameter file ----------*/
                   10312:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   10313:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   10314:     strcat(rfileres,".");    /* */
                   10315:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10316:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  10317:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10318:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  10319:     }
                   10320:     fprintf(ficres,"#%s\n",version);
                   10321:   }    /* End of mle != -3 */
1.218     brouard  10322:   
1.186     brouard  10323:   /*  Main data
                   10324:    */
1.126     brouard  10325:   n= lastobs;
                   10326:   num=lvector(1,n);
                   10327:   moisnais=vector(1,n);
                   10328:   annais=vector(1,n);
                   10329:   moisdc=vector(1,n);
                   10330:   andc=vector(1,n);
1.220     brouard  10331:   weight=vector(1,n);
1.126     brouard  10332:   agedc=vector(1,n);
                   10333:   cod=ivector(1,n);
1.220     brouard  10334:   for(i=1;i<=n;i++){
1.234     brouard  10335:     num[i]=0;
                   10336:     moisnais[i]=0;
                   10337:     annais[i]=0;
                   10338:     moisdc[i]=0;
                   10339:     andc[i]=0;
                   10340:     agedc[i]=0;
                   10341:     cod[i]=0;
                   10342:     weight[i]=1.0; /* Equal weights, 1 by default */
                   10343:   }
1.126     brouard  10344:   mint=matrix(1,maxwav,1,n);
                   10345:   anint=matrix(1,maxwav,1,n);
1.131     brouard  10346:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  10347:   tab=ivector(1,NCOVMAX);
1.144     brouard  10348:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  10349:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  10350: 
1.136     brouard  10351:   /* Reads data from file datafile */
                   10352:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   10353:     goto end;
                   10354: 
                   10355:   /* Calculation of the number of parameters from char model */
1.234     brouard  10356:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  10357:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   10358:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   10359:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   10360:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  10361:   */
                   10362:   
                   10363:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   10364:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   10365:   TvarsD=ivector(1,NCOVMAX); /*  */
                   10366:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   10367:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  10368:   TvarF=ivector(1,NCOVMAX); /*  */
                   10369:   TvarFind=ivector(1,NCOVMAX); /*  */
                   10370:   TvarV=ivector(1,NCOVMAX); /*  */
                   10371:   TvarVind=ivector(1,NCOVMAX); /*  */
                   10372:   TvarA=ivector(1,NCOVMAX); /*  */
                   10373:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  10374:   TvarFD=ivector(1,NCOVMAX); /*  */
                   10375:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   10376:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   10377:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   10378:   TvarVD=ivector(1,NCOVMAX); /*  */
                   10379:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   10380:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   10381:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   10382: 
1.230     brouard  10383:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  10384:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  10385:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   10386:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   10387:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  10388:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   10389:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   10390:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   10391:   */
                   10392:   /* For model-covariate k tells which data-covariate to use but
                   10393:     because this model-covariate is a construction we invent a new column
                   10394:     ncovcol + k1
                   10395:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   10396:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  10397:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   10398:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  10399:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   10400:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  10401:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  10402:   */
1.145     brouard  10403:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   10404:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  10405:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   10406:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  10407:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  10408:                         4 covariates (3 plus signs)
                   10409:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   10410:                      */  
1.230     brouard  10411:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  10412:                                * individual dummy, fixed or varying:
                   10413:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   10414:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  10415:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   10416:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   10417:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   10418:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   10419:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  10420:                                * individual quantitative, fixed or varying:
                   10421:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   10422:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   10423:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  10424: /* Main decodemodel */
                   10425: 
1.187     brouard  10426: 
1.223     brouard  10427:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  10428:     goto end;
                   10429: 
1.137     brouard  10430:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   10431:     nbwarn++;
                   10432:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10433:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10434:   }
1.136     brouard  10435:     /*  if(mle==1){*/
1.137     brouard  10436:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   10437:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  10438:   }
                   10439: 
                   10440:     /*-calculation of age at interview from date of interview and age at death -*/
                   10441:   agev=matrix(1,maxwav,1,imx);
                   10442: 
                   10443:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   10444:     goto end;
                   10445: 
1.126     brouard  10446: 
1.136     brouard  10447:   agegomp=(int)agemin;
                   10448:   free_vector(moisnais,1,n);
                   10449:   free_vector(annais,1,n);
1.126     brouard  10450:   /* free_matrix(mint,1,maxwav,1,n);
                   10451:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  10452:   /* free_vector(moisdc,1,n); */
                   10453:   /* free_vector(andc,1,n); */
1.145     brouard  10454:   /* */
                   10455:   
1.126     brouard  10456:   wav=ivector(1,imx);
1.214     brouard  10457:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10458:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10459:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10460:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   10461:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   10462:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  10463:    
                   10464:   /* Concatenates waves */
1.214     brouard  10465:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   10466:      Death is a valid wave (if date is known).
                   10467:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   10468:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   10469:      and mw[mi+1][i]. dh depends on stepm.
                   10470:   */
                   10471: 
1.126     brouard  10472:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  10473:   /* Concatenates waves */
1.145     brouard  10474:  
1.215     brouard  10475:   free_vector(moisdc,1,n);
                   10476:   free_vector(andc,1,n);
                   10477: 
1.126     brouard  10478:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   10479:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   10480:   ncodemax[1]=1;
1.145     brouard  10481:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  10482:   cptcoveff=0;
1.220     brouard  10483:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   10484:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  10485:   }
                   10486:   
                   10487:   ncovcombmax=pow(2,cptcoveff);
                   10488:   invalidvarcomb=ivector(1, ncovcombmax); 
                   10489:   for(i=1;i<ncovcombmax;i++)
                   10490:     invalidvarcomb[i]=0;
                   10491:   
1.211     brouard  10492:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  10493:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  10494:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  10495:   
1.200     brouard  10496:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  10497:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  10498:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  10499:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   10500:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   10501:    * (currently 0 or 1) in the data.
                   10502:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   10503:    * corresponding modality (h,j).
                   10504:    */
                   10505: 
1.145     brouard  10506:   h=0;
                   10507:   /*if (cptcovn > 0) */
1.126     brouard  10508:   m=pow(2,cptcoveff);
                   10509:  
1.144     brouard  10510:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  10511:           * For k=4 covariates, h goes from 1 to m=2**k
                   10512:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   10513:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  10514:           *     h\k   1     2     3     4
1.143     brouard  10515:           *______________________________  
                   10516:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   10517:           *     2     2     1     1     1
                   10518:           *     3 i=2 1     2     1     1
                   10519:           *     4     2     2     1     1
                   10520:           *     5 i=3 1 i=2 1     2     1
                   10521:           *     6     2     1     2     1
                   10522:           *     7 i=4 1     2     2     1
                   10523:           *     8     2     2     2     1
1.197     brouard  10524:           *     9 i=5 1 i=3 1 i=2 1     2
                   10525:           *    10     2     1     1     2
                   10526:           *    11 i=6 1     2     1     2
                   10527:           *    12     2     2     1     2
                   10528:           *    13 i=7 1 i=4 1     2     2    
                   10529:           *    14     2     1     2     2
                   10530:           *    15 i=8 1     2     2     2
                   10531:           *    16     2     2     2     2
1.143     brouard  10532:           */
1.212     brouard  10533:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  10534:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   10535:      * and the value of each covariate?
                   10536:      * V1=1, V2=1, V3=2, V4=1 ?
                   10537:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   10538:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   10539:      * In order to get the real value in the data, we use nbcode
                   10540:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   10541:      * We are keeping this crazy system in order to be able (in the future?) 
                   10542:      * to have more than 2 values (0 or 1) for a covariate.
                   10543:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   10544:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   10545:      *              bbbbbbbb
                   10546:      *              76543210     
                   10547:      *   h-1        00000101 (6-1=5)
1.219     brouard  10548:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  10549:      *           &
                   10550:      *     1        00000001 (1)
1.219     brouard  10551:      *              00000000        = 1 & ((h-1) >> (k-1))
                   10552:      *          +1= 00000001 =1 
1.211     brouard  10553:      *
                   10554:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   10555:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   10556:      *    >>k'            11
                   10557:      *          &   00000001
                   10558:      *            = 00000001
                   10559:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   10560:      * Reverse h=6 and m=16?
                   10561:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   10562:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   10563:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   10564:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   10565:      * V3=decodtabm(14,3,2**4)=2
                   10566:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   10567:      *(h-1) >> (j-1)    0011 =13 >> 2
                   10568:      *          &1 000000001
                   10569:      *           = 000000001
                   10570:      *         +1= 000000010 =2
                   10571:      *                  2211
                   10572:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   10573:      *                  V3=2
1.220     brouard  10574:                 * codtabm and decodtabm are identical
1.211     brouard  10575:      */
                   10576: 
1.145     brouard  10577: 
                   10578:  free_ivector(Ndum,-1,NCOVMAX);
                   10579: 
                   10580: 
1.126     brouard  10581:     
1.186     brouard  10582:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  10583:   strcpy(optionfilegnuplot,optionfilefiname);
                   10584:   if(mle==-3)
1.201     brouard  10585:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  10586:   strcat(optionfilegnuplot,".gp");
                   10587: 
                   10588:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   10589:     printf("Problem with file %s",optionfilegnuplot);
                   10590:   }
                   10591:   else{
1.204     brouard  10592:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  10593:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  10594:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   10595:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  10596:   }
                   10597:   /*  fclose(ficgp);*/
1.186     brouard  10598: 
                   10599: 
                   10600:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  10601: 
                   10602:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   10603:   if(mle==-3)
1.201     brouard  10604:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  10605:   strcat(optionfilehtm,".htm");
                   10606:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  10607:     printf("Problem with %s \n",optionfilehtm);
                   10608:     exit(0);
1.126     brouard  10609:   }
                   10610: 
                   10611:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   10612:   strcat(optionfilehtmcov,"-cov.htm");
                   10613:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   10614:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   10615:   }
                   10616:   else{
                   10617:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   10618: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10619: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  10620:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   10621:   }
                   10622: 
1.213     brouard  10623:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  10624: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   10625: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  10626: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10627: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  10628: \n\
                   10629: <hr  size=\"2\" color=\"#EC5E5E\">\
                   10630:  <ul><li><h4>Parameter files</h4>\n\
                   10631:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   10632:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   10633:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   10634:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   10635:  - Date and time at start: %s</ul>\n",\
                   10636:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   10637:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   10638:          fileres,fileres,\
                   10639:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   10640:   fflush(fichtm);
                   10641: 
                   10642:   strcpy(pathr,path);
                   10643:   strcat(pathr,optionfilefiname);
1.184     brouard  10644: #ifdef WIN32
                   10645:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   10646: #else
1.126     brouard  10647:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  10648: #endif
                   10649:          
1.126     brouard  10650:   
1.220     brouard  10651:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   10652:                 and for any valid combination of covariates
1.126     brouard  10653:      and prints on file fileres'p'. */
1.251     brouard  10654:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  10655:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  10656: 
                   10657:   fprintf(fichtm,"\n");
                   10658:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   10659: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   10660: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   10661:          imx,agemin,agemax,jmin,jmax,jmean);
                   10662:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.220     brouard  10663:        oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10664:        newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10665:        savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10666:        oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  10667: 
1.126     brouard  10668:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   10669:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   10670:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   10671: 
                   10672:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  10673:   /* For mortality only */
1.126     brouard  10674:   if (mle==-3){
1.136     brouard  10675:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  10676:     for(i=1;i<=NDIM;i++)
                   10677:       for(j=1;j<=NDIM;j++)
                   10678:        ximort[i][j]=0.;
1.186     brouard  10679:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  10680:     cens=ivector(1,n);
                   10681:     ageexmed=vector(1,n);
                   10682:     agecens=vector(1,n);
                   10683:     dcwave=ivector(1,n);
1.223     brouard  10684:                
1.126     brouard  10685:     for (i=1; i<=imx; i++){
                   10686:       dcwave[i]=-1;
                   10687:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  10688:        if (s[m][i]>nlstate) {
                   10689:          dcwave[i]=m;
                   10690:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   10691:          break;
                   10692:        }
1.126     brouard  10693:     }
1.226     brouard  10694:     
1.126     brouard  10695:     for (i=1; i<=imx; i++) {
                   10696:       if (wav[i]>0){
1.226     brouard  10697:        ageexmed[i]=agev[mw[1][i]][i];
                   10698:        j=wav[i];
                   10699:        agecens[i]=1.; 
                   10700:        
                   10701:        if (ageexmed[i]> 1 && wav[i] > 0){
                   10702:          agecens[i]=agev[mw[j][i]][i];
                   10703:          cens[i]= 1;
                   10704:        }else if (ageexmed[i]< 1) 
                   10705:          cens[i]= -1;
                   10706:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   10707:          cens[i]=0 ;
1.126     brouard  10708:       }
                   10709:       else cens[i]=-1;
                   10710:     }
                   10711:     
                   10712:     for (i=1;i<=NDIM;i++) {
                   10713:       for (j=1;j<=NDIM;j++)
1.226     brouard  10714:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  10715:     }
                   10716:     
1.145     brouard  10717:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  10718:     /*printf("%lf %lf", p[1], p[2]);*/
                   10719:     
                   10720:     
1.136     brouard  10721: #ifdef GSL
                   10722:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  10723: #else
1.126     brouard  10724:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  10725: #endif
1.201     brouard  10726:     strcpy(filerespow,"POW-MORT_"); 
                   10727:     strcat(filerespow,fileresu);
1.126     brouard  10728:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   10729:       printf("Problem with resultfile: %s\n", filerespow);
                   10730:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   10731:     }
1.136     brouard  10732: #ifdef GSL
                   10733:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  10734: #else
1.126     brouard  10735:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  10736: #endif
1.126     brouard  10737:     /*  for (i=1;i<=nlstate;i++)
                   10738:        for(j=1;j<=nlstate+ndeath;j++)
                   10739:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   10740:     */
                   10741:     fprintf(ficrespow,"\n");
1.136     brouard  10742: #ifdef GSL
                   10743:     /* gsl starts here */ 
                   10744:     T = gsl_multimin_fminimizer_nmsimplex;
                   10745:     gsl_multimin_fminimizer *sfm = NULL;
                   10746:     gsl_vector *ss, *x;
                   10747:     gsl_multimin_function minex_func;
                   10748: 
                   10749:     /* Initial vertex size vector */
                   10750:     ss = gsl_vector_alloc (NDIM);
                   10751:     
                   10752:     if (ss == NULL){
                   10753:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   10754:     }
                   10755:     /* Set all step sizes to 1 */
                   10756:     gsl_vector_set_all (ss, 0.001);
                   10757: 
                   10758:     /* Starting point */
1.126     brouard  10759:     
1.136     brouard  10760:     x = gsl_vector_alloc (NDIM);
                   10761:     
                   10762:     if (x == NULL){
                   10763:       gsl_vector_free(ss);
                   10764:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   10765:     }
                   10766:   
                   10767:     /* Initialize method and iterate */
                   10768:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  10769:     /*     gsl_vector_set(x, 0, 0.0268); */
                   10770:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  10771:     gsl_vector_set(x, 0, p[1]);
                   10772:     gsl_vector_set(x, 1, p[2]);
                   10773: 
                   10774:     minex_func.f = &gompertz_f;
                   10775:     minex_func.n = NDIM;
                   10776:     minex_func.params = (void *)&p; /* ??? */
                   10777:     
                   10778:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   10779:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   10780:     
                   10781:     printf("Iterations beginning .....\n\n");
                   10782:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   10783: 
                   10784:     iteri=0;
                   10785:     while (rval == GSL_CONTINUE){
                   10786:       iteri++;
                   10787:       status = gsl_multimin_fminimizer_iterate(sfm);
                   10788:       
                   10789:       if (status) printf("error: %s\n", gsl_strerror (status));
                   10790:       fflush(0);
                   10791:       
                   10792:       if (status) 
                   10793:         break;
                   10794:       
                   10795:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   10796:       ssval = gsl_multimin_fminimizer_size (sfm);
                   10797:       
                   10798:       if (rval == GSL_SUCCESS)
                   10799:         printf ("converged to a local maximum at\n");
                   10800:       
                   10801:       printf("%5d ", iteri);
                   10802:       for (it = 0; it < NDIM; it++){
                   10803:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   10804:       }
                   10805:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   10806:     }
                   10807:     
                   10808:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   10809:     
                   10810:     gsl_vector_free(x); /* initial values */
                   10811:     gsl_vector_free(ss); /* inital step size */
                   10812:     for (it=0; it<NDIM; it++){
                   10813:       p[it+1]=gsl_vector_get(sfm->x,it);
                   10814:       fprintf(ficrespow," %.12lf", p[it]);
                   10815:     }
                   10816:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   10817: #endif
                   10818: #ifdef POWELL
                   10819:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   10820: #endif  
1.126     brouard  10821:     fclose(ficrespow);
                   10822:     
1.203     brouard  10823:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  10824: 
                   10825:     for(i=1; i <=NDIM; i++)
                   10826:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  10827:                                matcov[i][j]=matcov[j][i];
1.126     brouard  10828:     
                   10829:     printf("\nCovariance matrix\n ");
1.203     brouard  10830:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  10831:     for(i=1; i <=NDIM; i++) {
                   10832:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  10833:                                printf("%f ",matcov[i][j]);
                   10834:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  10835:       }
1.203     brouard  10836:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  10837:     }
                   10838:     
                   10839:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  10840:     for (i=1;i<=NDIM;i++) {
1.126     brouard  10841:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  10842:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   10843:     }
1.126     brouard  10844:     lsurv=vector(1,AGESUP);
                   10845:     lpop=vector(1,AGESUP);
                   10846:     tpop=vector(1,AGESUP);
                   10847:     lsurv[agegomp]=100000;
                   10848:     
                   10849:     for (k=agegomp;k<=AGESUP;k++) {
                   10850:       agemortsup=k;
                   10851:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   10852:     }
                   10853:     
                   10854:     for (k=agegomp;k<agemortsup;k++)
                   10855:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   10856:     
                   10857:     for (k=agegomp;k<agemortsup;k++){
                   10858:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   10859:       sumlpop=sumlpop+lpop[k];
                   10860:     }
                   10861:     
                   10862:     tpop[agegomp]=sumlpop;
                   10863:     for (k=agegomp;k<(agemortsup-3);k++){
                   10864:       /*  tpop[k+1]=2;*/
                   10865:       tpop[k+1]=tpop[k]-lpop[k];
                   10866:     }
                   10867:     
                   10868:     
                   10869:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   10870:     for (k=agegomp;k<(agemortsup-2);k++) 
                   10871:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   10872:     
                   10873:     
                   10874:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  10875:                ageminpar=50;
                   10876:                agemaxpar=100;
1.194     brouard  10877:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   10878:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10879: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10880: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   10881:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10882: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10883: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10884:     }else{
                   10885:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   10886:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  10887:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  10888:                }
1.201     brouard  10889:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  10890:                     stepm, weightopt,\
                   10891:                     model,imx,p,matcov,agemortsup);
                   10892:     
                   10893:     free_vector(lsurv,1,AGESUP);
                   10894:     free_vector(lpop,1,AGESUP);
                   10895:     free_vector(tpop,1,AGESUP);
1.220     brouard  10896:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  10897:     free_ivector(cens,1,n);
                   10898:     free_vector(agecens,1,n);
                   10899:     free_ivector(dcwave,1,n);
1.220     brouard  10900: #ifdef GSL
1.136     brouard  10901: #endif
1.186     brouard  10902:   } /* Endof if mle==-3 mortality only */
1.205     brouard  10903:   /* Standard  */
                   10904:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   10905:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10906:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  10907:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  10908:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10909:     for (k=1; k<=npar;k++)
                   10910:       printf(" %d %8.5f",k,p[k]);
                   10911:     printf("\n");
1.205     brouard  10912:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   10913:       /* mlikeli uses func not funcone */
1.247     brouard  10914:       /* for(i=1;i<nlstate;i++){ */
                   10915:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10916:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10917:       /* } */
1.205     brouard  10918:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   10919:     }
                   10920:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   10921:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10922:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   10923:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10924:     }
                   10925:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  10926:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10927:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10928:     for (k=1; k<=npar;k++)
                   10929:       printf(" %d %8.5f",k,p[k]);
                   10930:     printf("\n");
                   10931:     
                   10932:     /*--------- results files --------------*/
1.224     brouard  10933:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  10934:     
                   10935:     
                   10936:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10937:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10938:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10939:     for(i=1,jk=1; i <=nlstate; i++){
                   10940:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  10941:        if (k != i) {
                   10942:          printf("%d%d ",i,k);
                   10943:          fprintf(ficlog,"%d%d ",i,k);
                   10944:          fprintf(ficres,"%1d%1d ",i,k);
                   10945:          for(j=1; j <=ncovmodel; j++){
                   10946:            printf("%12.7f ",p[jk]);
                   10947:            fprintf(ficlog,"%12.7f ",p[jk]);
                   10948:            fprintf(ficres,"%12.7f ",p[jk]);
                   10949:            jk++; 
                   10950:          }
                   10951:          printf("\n");
                   10952:          fprintf(ficlog,"\n");
                   10953:          fprintf(ficres,"\n");
                   10954:        }
1.126     brouard  10955:       }
                   10956:     }
1.203     brouard  10957:     if(mle != 0){
                   10958:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  10959:       ftolhess=ftol; /* Usually correct */
1.203     brouard  10960:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   10961:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10962:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10963:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  10964:        for(k=1; k <=(nlstate+ndeath); k++){
                   10965:          if (k != i) {
                   10966:            printf("%d%d ",i,k);
                   10967:            fprintf(ficlog,"%d%d ",i,k);
                   10968:            for(j=1; j <=ncovmodel; j++){
                   10969:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10970:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10971:              jk++; 
                   10972:            }
                   10973:            printf("\n");
                   10974:            fprintf(ficlog,"\n");
                   10975:          }
                   10976:        }
1.193     brouard  10977:       }
1.203     brouard  10978:     } /* end of hesscov and Wald tests */
1.225     brouard  10979:     
1.203     brouard  10980:     /*  */
1.126     brouard  10981:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   10982:     printf("# Scales (for hessian or gradient estimation)\n");
                   10983:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   10984:     for(i=1,jk=1; i <=nlstate; i++){
                   10985:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  10986:        if (j!=i) {
                   10987:          fprintf(ficres,"%1d%1d",i,j);
                   10988:          printf("%1d%1d",i,j);
                   10989:          fprintf(ficlog,"%1d%1d",i,j);
                   10990:          for(k=1; k<=ncovmodel;k++){
                   10991:            printf(" %.5e",delti[jk]);
                   10992:            fprintf(ficlog," %.5e",delti[jk]);
                   10993:            fprintf(ficres," %.5e",delti[jk]);
                   10994:            jk++;
                   10995:          }
                   10996:          printf("\n");
                   10997:          fprintf(ficlog,"\n");
                   10998:          fprintf(ficres,"\n");
                   10999:        }
1.126     brouard  11000:       }
                   11001:     }
                   11002:     
                   11003:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  11004:     if(mle >= 1) /* To big for the screen */
1.126     brouard  11005:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11006:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11007:     /* # 121 Var(a12)\n\ */
                   11008:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   11009:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   11010:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   11011:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   11012:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   11013:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   11014:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   11015:     
                   11016:     
                   11017:     /* Just to have a covariance matrix which will be more understandable
                   11018:        even is we still don't want to manage dictionary of variables
                   11019:     */
                   11020:     for(itimes=1;itimes<=2;itimes++){
                   11021:       jj=0;
                   11022:       for(i=1; i <=nlstate; i++){
1.225     brouard  11023:        for(j=1; j <=nlstate+ndeath; j++){
                   11024:          if(j==i) continue;
                   11025:          for(k=1; k<=ncovmodel;k++){
                   11026:            jj++;
                   11027:            ca[0]= k+'a'-1;ca[1]='\0';
                   11028:            if(itimes==1){
                   11029:              if(mle>=1)
                   11030:                printf("#%1d%1d%d",i,j,k);
                   11031:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   11032:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   11033:            }else{
                   11034:              if(mle>=1)
                   11035:                printf("%1d%1d%d",i,j,k);
                   11036:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   11037:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   11038:            }
                   11039:            ll=0;
                   11040:            for(li=1;li <=nlstate; li++){
                   11041:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   11042:                if(lj==li) continue;
                   11043:                for(lk=1;lk<=ncovmodel;lk++){
                   11044:                  ll++;
                   11045:                  if(ll<=jj){
                   11046:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   11047:                    if(ll<jj){
                   11048:                      if(itimes==1){
                   11049:                        if(mle>=1)
                   11050:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11051:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11052:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11053:                      }else{
                   11054:                        if(mle>=1)
                   11055:                          printf(" %.5e",matcov[jj][ll]); 
                   11056:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   11057:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   11058:                      }
                   11059:                    }else{
                   11060:                      if(itimes==1){
                   11061:                        if(mle>=1)
                   11062:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   11063:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   11064:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   11065:                      }else{
                   11066:                        if(mle>=1)
                   11067:                          printf(" %.7e",matcov[jj][ll]); 
                   11068:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   11069:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   11070:                      }
                   11071:                    }
                   11072:                  }
                   11073:                } /* end lk */
                   11074:              } /* end lj */
                   11075:            } /* end li */
                   11076:            if(mle>=1)
                   11077:              printf("\n");
                   11078:            fprintf(ficlog,"\n");
                   11079:            fprintf(ficres,"\n");
                   11080:            numlinepar++;
                   11081:          } /* end k*/
                   11082:        } /*end j */
1.126     brouard  11083:       } /* end i */
                   11084:     } /* end itimes */
                   11085:     
                   11086:     fflush(ficlog);
                   11087:     fflush(ficres);
1.225     brouard  11088:     while(fgets(line, MAXLINE, ficpar)) {
                   11089:       /* If line starts with a # it is a comment */
                   11090:       if (line[0] == '#') {
                   11091:        numlinepar++;
                   11092:        fputs(line,stdout);
                   11093:        fputs(line,ficparo);
                   11094:        fputs(line,ficlog);
                   11095:        continue;
                   11096:       }else
                   11097:        break;
                   11098:     }
                   11099:     
1.209     brouard  11100:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11101:     /*   ungetc(c,ficpar); */
                   11102:     /*   fgets(line, MAXLINE, ficpar); */
                   11103:     /*   fputs(line,stdout); */
                   11104:     /*   fputs(line,ficparo); */
                   11105:     /* } */
                   11106:     /* ungetc(c,ficpar); */
1.126     brouard  11107:     
                   11108:     estepm=0;
1.209     brouard  11109:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  11110:       
                   11111:       if (num_filled != 6) {
                   11112:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11113:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11114:        goto end;
                   11115:       }
                   11116:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   11117:     }
                   11118:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   11119:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   11120:     
1.209     brouard  11121:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  11122:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   11123:     if (fage <= 2) {
                   11124:       bage = ageminpar;
                   11125:       fage = agemaxpar;
                   11126:     }
                   11127:     
                   11128:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  11129:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   11130:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  11131:                
1.186     brouard  11132:     /* Other stuffs, more or less useful */    
1.254     brouard  11133:     while(fgets(line, MAXLINE, ficpar)) {
                   11134:       /* If line starts with a # it is a comment */
                   11135:       if (line[0] == '#') {
                   11136:        numlinepar++;
                   11137:        fputs(line,stdout);
                   11138:        fputs(line,ficparo);
                   11139:        fputs(line,ficlog);
                   11140:        continue;
                   11141:       }else
                   11142:        break;
                   11143:     }
                   11144: 
                   11145:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   11146:       
                   11147:       if (num_filled != 7) {
                   11148:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11149:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11150:        goto end;
                   11151:       }
                   11152:     /* fscanf(ficpar,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav); */
                   11153:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11154:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11155:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11156:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11157:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  11158:     }
1.254     brouard  11159: 
                   11160:     while(fgets(line, MAXLINE, ficpar)) {
                   11161:       /* If line starts with a # it is a comment */
                   11162:       if (line[0] == '#') {
                   11163:        numlinepar++;
                   11164:        fputs(line,stdout);
                   11165:        fputs(line,ficparo);
                   11166:        fputs(line,ficlog);
                   11167:        continue;
                   11168:       }else
                   11169:        break;
1.126     brouard  11170:     }
                   11171:     
                   11172:     
                   11173:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   11174:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   11175:     
1.254     brouard  11176:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   11177:       if (num_filled != 1) {
                   11178:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11179:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11180:        goto end;
                   11181:       }
                   11182:       printf("pop_based=%d\n",popbased);
                   11183:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   11184:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   11185:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   11186:     }
                   11187:      
                   11188:     while(fgets(line, MAXLINE, ficpar)) {
                   11189:       /* If line starts with a # it is a comment */
                   11190:       if (line[0] == '#') {
                   11191:        numlinepar++;
                   11192:        fputs(line,stdout);
                   11193:        fputs(line,ficparo);
                   11194:        fputs(line,ficlog);
                   11195:        continue;
                   11196:       }else
                   11197:        break;
1.126     brouard  11198:     }
1.254     brouard  11199:    /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11200:    /*    ungetc(c,ficpar); */
                   11201:    /*    fgets(line, MAXLINE, ficpar); */
                   11202:    /*    fputs(line,stdout); */
                   11203:    /*    fputs(line,ficres); */
                   11204:    /*    fputs(line,ficparo); */
                   11205:    /*  } */
                   11206:    /*  ungetc(c,ficpar); */
                   11207:     
                   11208:     /* fscanf(ficpar,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj); */
                   11209:     if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   11210:       if (num_filled != 8) {
                   11211:        printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11212:        fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11213:        goto end;
                   11214:       }
                   11215:      fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11216:      printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11217:      fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11218:      fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
1.126     brouard  11219:     /* day and month of proj2 are not used but only year anproj2.*/
1.217     brouard  11220:     }
1.254     brouard  11221:      while(fgets(line, MAXLINE, ficpar)) {
                   11222:       /* If line starts with a # it is a comment */
                   11223:       if (line[0] == '#') {
                   11224:        numlinepar++;
                   11225:        fputs(line,stdout);
                   11226:        fputs(line,ficparo);
                   11227:        fputs(line,ficlog);
                   11228:        continue;
                   11229:       }else
                   11230:        break;
                   11231:     }
                   11232:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11233:     /*   ungetc(c,ficpar); */
                   11234:     /*   fgets(line, MAXLINE, ficpar); */
                   11235:     /*   fputs(line,stdout); */
                   11236:     /*   fputs(line,ficparo); */
                   11237:     /*   fputs(line,ficres); */
                   11238:     /* } */
                   11239:     /* ungetc(c,ficpar); */
1.217     brouard  11240:     
                   11241:     fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);
1.254     brouard  11242:     if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   11243:       if (num_filled != 8) {
                   11244:        printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 finloal-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11245:        fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 finloal-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11246:        goto end;
                   11247:       }
                   11248:       printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11249:       fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11250:       fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11251:       fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
1.217     brouard  11252:     /* day and month of proj2 are not used but only year anproj2.*/
1.254     brouard  11253:     }
1.230     brouard  11254:     /* Results */
1.235     brouard  11255:     nresult=0;
1.230     brouard  11256:     while(fgets(line, MAXLINE, ficpar)) {
                   11257:       /* If line starts with a # it is a comment */
                   11258:       if (line[0] == '#') {
                   11259:        numlinepar++;
                   11260:        fputs(line,stdout);
                   11261:        fputs(line,ficparo);
                   11262:        fputs(line,ficlog);
1.238     brouard  11263:        fputs(line,ficres);
1.230     brouard  11264:        continue;
                   11265:       }else
                   11266:        break;
                   11267:     }
1.240     brouard  11268:     if (!feof(ficpar))
1.230     brouard  11269:     while((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
1.240     brouard  11270:       if (num_filled == 0){
1.230     brouard  11271:        resultline[0]='\0';
1.253     brouard  11272:        printf("Warning %d: no result line should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
1.240     brouard  11273:       break;
                   11274:       } else if (num_filled != 1){
1.253     brouard  11275:        printf("ERROR %d: result line should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
1.230     brouard  11276:       }
1.235     brouard  11277:       nresult++; /* Sum of resultlines */
                   11278:       printf("Result %d: result=%s\n",nresult, resultline);
                   11279:       if(nresult > MAXRESULTLINES){
                   11280:        printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11281:        fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11282:        goto end;
                   11283:       }
                   11284:       decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
1.238     brouard  11285:       fprintf(ficparo,"result: %s\n",resultline);
                   11286:       fprintf(ficres,"result: %s\n",resultline);
                   11287:       fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  11288:       while(fgets(line, MAXLINE, ficpar)) {
                   11289:        /* If line starts with a # it is a comment */
                   11290:        if (line[0] == '#') {
                   11291:          numlinepar++;
                   11292:          fputs(line,stdout);
                   11293:          fputs(line,ficparo);
1.238     brouard  11294:          fputs(line,ficres);
1.230     brouard  11295:          fputs(line,ficlog);
                   11296:          continue;
                   11297:        }else
                   11298:          break;
                   11299:       }
                   11300:       if (feof(ficpar))
                   11301:        break;
                   11302:       else{ /* Processess output results for this combination of covariate values */
                   11303:       }                                   
1.240     brouard  11304:     } /* end while */
1.230     brouard  11305: 
                   11306: 
1.126     brouard  11307:     
1.230     brouard  11308:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  11309:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  11310:     
                   11311:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  11312:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  11313:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11314: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11315: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  11316:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11317: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11318: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11319:     }else{
1.218     brouard  11320:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p);
1.220     brouard  11321:     }
                   11322:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.225     brouard  11323:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,prevfcast,backcast, estepm, \
                   11324:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  11325:                
1.225     brouard  11326:     /*------------ free_vector  -------------*/
                   11327:     /*  chdir(path); */
1.220     brouard  11328:                
1.215     brouard  11329:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   11330:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   11331:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   11332:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  11333:     free_lvector(num,1,n);
                   11334:     free_vector(agedc,1,n);
                   11335:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   11336:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   11337:     fclose(ficparo);
                   11338:     fclose(ficres);
1.220     brouard  11339:                
                   11340:                
1.186     brouard  11341:     /* Other results (useful)*/
1.220     brouard  11342:                
                   11343:                
1.126     brouard  11344:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  11345:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   11346:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  11347:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  11348:     fclose(ficrespl);
                   11349: 
                   11350:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  11351:     /*#include "hpijx.h"*/
                   11352:     hPijx(p, bage, fage);
1.145     brouard  11353:     fclose(ficrespij);
1.227     brouard  11354:     
1.220     brouard  11355:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  11356:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  11357:     k=1;
1.126     brouard  11358:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  11359:     
1.219     brouard  11360:     /* Prevalence for each covariates in probs[age][status][cov] */
1.218     brouard  11361:     probs= ma3x(1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.126     brouard  11362:     for(i=1;i<=AGESUP;i++)
1.219     brouard  11363:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  11364:        for(k=1;k<=ncovcombmax;k++)
                   11365:          probs[i][j][k]=0.;
1.219     brouard  11366:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
                   11367:     if (mobilav!=0 ||mobilavproj !=0 ) {
                   11368:       mobaverages= ma3x(1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.227     brouard  11369:       for(i=1;i<=AGESUP;i++)
                   11370:        for(j=1;j<=nlstate;j++)
                   11371:          for(k=1;k<=ncovcombmax;k++)
                   11372:            mobaverages[i][j][k]=0.;
1.219     brouard  11373:       mobaverage=mobaverages;
                   11374:       if (mobilav!=0) {
1.235     brouard  11375:        printf("Movingaveraging observed prevalence\n");
1.227     brouard  11376:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   11377:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   11378:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   11379:        }
1.219     brouard  11380:       }
                   11381:       /* /\* Prevalence for each covariates in probs[age][status][cov] *\/ */
                   11382:       /* prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   11383:       else if (mobilavproj !=0) {
1.235     brouard  11384:        printf("Movingaveraging projected observed prevalence\n");
1.227     brouard  11385:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   11386:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11387:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11388:        }
1.219     brouard  11389:       }
                   11390:     }/* end if moving average */
1.227     brouard  11391:     
1.126     brouard  11392:     /*---------- Forecasting ------------------*/
                   11393:     /*if((stepm == 1) && (strcmp(model,".")==0)){*/
                   11394:     if(prevfcast==1){
                   11395:       /*    if(stepm ==1){*/
1.225     brouard  11396:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  11397:     }
1.217     brouard  11398:     if(backcast==1){
1.219     brouard  11399:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11400:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11401:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   11402: 
                   11403:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   11404: 
                   11405:       bprlim=matrix(1,nlstate,1,nlstate);
                   11406:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   11407:       fclose(ficresplb);
                   11408: 
1.222     brouard  11409:       hBijx(p, bage, fage, mobaverage);
                   11410:       fclose(ficrespijb);
1.219     brouard  11411:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11412: 
                   11413:       /* prevbackforecast(fileresu, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, mobilavproj,
1.225     brouard  11414:         bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
1.219     brouard  11415:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11416:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11417:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11418:     }
1.217     brouard  11419:     
1.186     brouard  11420:  
                   11421:     /* ------ Other prevalence ratios------------ */
1.126     brouard  11422: 
1.215     brouard  11423:     free_ivector(wav,1,imx);
                   11424:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   11425:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   11426:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  11427:                
                   11428:                
1.127     brouard  11429:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  11430:                
1.201     brouard  11431:     strcpy(filerese,"E_");
                   11432:     strcat(filerese,fileresu);
1.126     brouard  11433:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   11434:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11435:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11436:     }
1.208     brouard  11437:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   11438:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  11439: 
                   11440:     pstamp(ficreseij);
1.219     brouard  11441:                
1.235     brouard  11442:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11443:     if (cptcovn < 1){i1=1;}
                   11444:     
                   11445:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11446:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11447:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11448:        continue;
1.219     brouard  11449:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  11450:       printf("\n#****** ");
1.225     brouard  11451:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11452:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11453:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11454:       }
                   11455:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11456:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11457:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  11458:       }
                   11459:       fprintf(ficreseij,"******\n");
1.235     brouard  11460:       printf("******\n");
1.219     brouard  11461:       
                   11462:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11463:       oldm=oldms;savm=savms;
1.235     brouard  11464:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  11465:       
1.219     brouard  11466:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  11467:     }
                   11468:     fclose(ficreseij);
1.208     brouard  11469:     printf("done evsij\n");fflush(stdout);
                   11470:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.218     brouard  11471:                
1.227     brouard  11472:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  11473:                
                   11474:                
1.201     brouard  11475:     strcpy(filerest,"T_");
                   11476:     strcat(filerest,fileresu);
1.127     brouard  11477:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   11478:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   11479:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   11480:     }
1.208     brouard  11481:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   11482:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.218     brouard  11483:                
1.126     brouard  11484: 
1.201     brouard  11485:     strcpy(fileresstde,"STDE_");
                   11486:     strcat(fileresstde,fileresu);
1.126     brouard  11487:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  11488:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   11489:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  11490:     }
1.227     brouard  11491:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   11492:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  11493: 
1.201     brouard  11494:     strcpy(filerescve,"CVE_");
                   11495:     strcat(filerescve,fileresu);
1.126     brouard  11496:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  11497:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   11498:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  11499:     }
1.227     brouard  11500:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   11501:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  11502: 
1.201     brouard  11503:     strcpy(fileresv,"V_");
                   11504:     strcat(fileresv,fileresu);
1.126     brouard  11505:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   11506:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11507:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11508:     }
1.227     brouard  11509:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   11510:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  11511: 
1.145     brouard  11512:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11513:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   11514:           
1.235     brouard  11515:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11516:     if (cptcovn < 1){i1=1;}
                   11517:     
                   11518:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11519:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11520:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11521:        continue;
1.242     brouard  11522:       printf("\n#****** Result for:");
                   11523:       fprintf(ficrest,"\n#****** Result for:");
                   11524:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  11525:       for(j=1;j<=cptcoveff;j++){ 
                   11526:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11527:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11528:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11529:       }
1.235     brouard  11530:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11531:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11532:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11533:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11534:       }        
1.208     brouard  11535:       fprintf(ficrest,"******\n");
1.227     brouard  11536:       fprintf(ficlog,"******\n");
                   11537:       printf("******\n");
1.208     brouard  11538:       
                   11539:       fprintf(ficresstdeij,"\n#****** ");
                   11540:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  11541:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11542:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11543:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  11544:       }
1.235     brouard  11545:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11546:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11547:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11548:       }        
1.208     brouard  11549:       fprintf(ficresstdeij,"******\n");
                   11550:       fprintf(ficrescveij,"******\n");
                   11551:       
                   11552:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  11553:       /* pstamp(ficresvij); */
1.225     brouard  11554:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  11555:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11556:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11557:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11558:       }        
1.208     brouard  11559:       fprintf(ficresvij,"******\n");
                   11560:       
                   11561:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11562:       oldm=oldms;savm=savms;
1.235     brouard  11563:       printf(" cvevsij ");
                   11564:       fprintf(ficlog, " cvevsij ");
                   11565:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  11566:       printf(" end cvevsij \n ");
                   11567:       fprintf(ficlog, " end cvevsij \n ");
                   11568:       
                   11569:       /*
                   11570:        */
                   11571:       /* goto endfree; */
                   11572:       
                   11573:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11574:       pstamp(ficrest);
                   11575:       
                   11576:       
                   11577:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  11578:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   11579:        cptcod= 0; /* To be deleted */
                   11580:        printf("varevsij vpopbased=%d \n",vpopbased);
                   11581:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  11582:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  11583:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   11584:        if(vpopbased==1)
                   11585:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   11586:        else
                   11587:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   11588:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   11589:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   11590:        fprintf(ficrest,"\n");
                   11591:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   11592:        epj=vector(1,nlstate+1);
                   11593:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   11594:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   11595:        for(age=bage; age <=fage ;age++){
1.235     brouard  11596:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  11597:          if (vpopbased==1) {
                   11598:            if(mobilav ==0){
                   11599:              for(i=1; i<=nlstate;i++)
                   11600:                prlim[i][i]=probs[(int)age][i][k];
                   11601:            }else{ /* mobilav */ 
                   11602:              for(i=1; i<=nlstate;i++)
                   11603:                prlim[i][i]=mobaverage[(int)age][i][k];
                   11604:            }
                   11605:          }
1.219     brouard  11606:          
1.227     brouard  11607:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   11608:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   11609:          /* printf(" age %4.0f ",age); */
                   11610:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   11611:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   11612:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   11613:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   11614:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   11615:            }
                   11616:            epj[nlstate+1] +=epj[j];
                   11617:          }
                   11618:          /* printf(" age %4.0f \n",age); */
1.219     brouard  11619:          
1.227     brouard  11620:          for(i=1, vepp=0.;i <=nlstate;i++)
                   11621:            for(j=1;j <=nlstate;j++)
                   11622:              vepp += vareij[i][j][(int)age];
                   11623:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   11624:          for(j=1;j <=nlstate;j++){
                   11625:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   11626:          }
                   11627:          fprintf(ficrest,"\n");
                   11628:        }
1.208     brouard  11629:       } /* End vpopbased */
                   11630:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11631:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11632:       free_vector(epj,1,nlstate+1);
1.235     brouard  11633:       printf("done selection\n");fflush(stdout);
                   11634:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  11635:       
1.145     brouard  11636:       /*}*/
1.235     brouard  11637:     } /* End k selection */
1.227     brouard  11638: 
                   11639:     printf("done State-specific expectancies\n");fflush(stdout);
                   11640:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   11641: 
1.126     brouard  11642:     /*------- Variance of period (stable) prevalence------*/   
1.227     brouard  11643:     
1.201     brouard  11644:     strcpy(fileresvpl,"VPL_");
                   11645:     strcat(fileresvpl,fileresu);
1.126     brouard  11646:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   11647:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   11648:       exit(0);
                   11649:     }
1.208     brouard  11650:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   11651:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.227     brouard  11652:     
1.145     brouard  11653:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11654:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
1.227     brouard  11655:     
1.235     brouard  11656:     i1=pow(2,cptcoveff);
                   11657:     if (cptcovn < 1){i1=1;}
                   11658: 
                   11659:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11660:     for(k=1; k<=i1;k++){
1.253     brouard  11661:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11662:        continue;
1.227     brouard  11663:       fprintf(ficresvpl,"\n#****** ");
                   11664:       printf("\n#****** ");
                   11665:       fprintf(ficlog,"\n#****** ");
                   11666:       for(j=1;j<=cptcoveff;j++) {
                   11667:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11668:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11669:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11670:       }
1.235     brouard  11671:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11672:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11673:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11674:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11675:       }        
1.227     brouard  11676:       fprintf(ficresvpl,"******\n");
                   11677:       printf("******\n");
                   11678:       fprintf(ficlog,"******\n");
                   11679:       
                   11680:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   11681:       oldm=oldms;savm=savms;
1.235     brouard  11682:       varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, strstart, nres);
1.227     brouard  11683:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
1.145     brouard  11684:       /*}*/
1.126     brouard  11685:     }
1.227     brouard  11686:     
1.126     brouard  11687:     fclose(ficresvpl);
1.208     brouard  11688:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   11689:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
1.227     brouard  11690:     
                   11691:     free_vector(weight,1,n);
                   11692:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   11693:     free_imatrix(s,1,maxwav+1,1,n);
                   11694:     free_matrix(anint,1,maxwav,1,n); 
                   11695:     free_matrix(mint,1,maxwav,1,n);
                   11696:     free_ivector(cod,1,n);
                   11697:     free_ivector(tab,1,NCOVMAX);
                   11698:     fclose(ficresstdeij);
                   11699:     fclose(ficrescveij);
                   11700:     fclose(ficresvij);
                   11701:     fclose(ficrest);
                   11702:     fclose(ficpar);
                   11703:     
                   11704:     
1.126     brouard  11705:     /*---------- End : free ----------------*/
1.219     brouard  11706:     if (mobilav!=0 ||mobilavproj !=0)
                   11707:       free_ma3x(mobaverages,1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
1.218     brouard  11708:     free_ma3x(probs,1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  11709:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11710:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  11711:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  11712:   /* endfree:*/
                   11713:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11714:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11715:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11716:   free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
1.233     brouard  11717:   free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
1.227     brouard  11718:   free_matrix(coqvar,1,maxwav,1,n);
                   11719:   free_matrix(covar,0,NCOVMAX,1,n);
                   11720:   free_matrix(matcov,1,npar,1,npar);
                   11721:   free_matrix(hess,1,npar,1,npar);
                   11722:   /*free_vector(delti,1,npar);*/
                   11723:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11724:   free_matrix(agev,1,maxwav,1,imx);
                   11725:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   11726:   
                   11727:   free_ivector(ncodemax,1,NCOVMAX);
                   11728:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   11729:   free_ivector(Dummy,-1,NCOVMAX);
                   11730:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  11731:   free_ivector(DummyV,1,NCOVMAX);
                   11732:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  11733:   free_ivector(Typevar,-1,NCOVMAX);
                   11734:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  11735:   free_ivector(TvarsQ,1,NCOVMAX);
                   11736:   free_ivector(TvarsQind,1,NCOVMAX);
                   11737:   free_ivector(TvarsD,1,NCOVMAX);
                   11738:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  11739:   free_ivector(TvarFD,1,NCOVMAX);
                   11740:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  11741:   free_ivector(TvarF,1,NCOVMAX);
                   11742:   free_ivector(TvarFind,1,NCOVMAX);
                   11743:   free_ivector(TvarV,1,NCOVMAX);
                   11744:   free_ivector(TvarVind,1,NCOVMAX);
                   11745:   free_ivector(TvarA,1,NCOVMAX);
                   11746:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  11747:   free_ivector(TvarFQ,1,NCOVMAX);
                   11748:   free_ivector(TvarFQind,1,NCOVMAX);
                   11749:   free_ivector(TvarVD,1,NCOVMAX);
                   11750:   free_ivector(TvarVDind,1,NCOVMAX);
                   11751:   free_ivector(TvarVQ,1,NCOVMAX);
                   11752:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  11753:   free_ivector(Tvarsel,1,NCOVMAX);
                   11754:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  11755:   free_ivector(Tposprod,1,NCOVMAX);
                   11756:   free_ivector(Tprod,1,NCOVMAX);
                   11757:   free_ivector(Tvaraff,1,NCOVMAX);
                   11758:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   11759:   free_ivector(Tage,1,NCOVMAX);
                   11760:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  11761:   free_ivector(TmodelInvind,1,NCOVMAX);
                   11762:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  11763:   
                   11764:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   11765:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  11766:   fflush(fichtm);
                   11767:   fflush(ficgp);
                   11768:   
1.227     brouard  11769:   
1.126     brouard  11770:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  11771:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   11772:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  11773:   }else{
                   11774:     printf("End of Imach\n");
                   11775:     fprintf(ficlog,"End of Imach\n");
                   11776:   }
                   11777:   printf("See log file on %s\n",filelog);
                   11778:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  11779:   /*(void) gettimeofday(&end_time,&tzp);*/
                   11780:   rend_time = time(NULL);  
                   11781:   end_time = *localtime(&rend_time);
                   11782:   /* tml = *localtime(&end_time.tm_sec); */
                   11783:   strcpy(strtend,asctime(&end_time));
1.126     brouard  11784:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   11785:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  11786:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  11787:   
1.157     brouard  11788:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   11789:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   11790:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  11791:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   11792: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   11793:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11794:   fclose(fichtm);
                   11795:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11796:   fclose(fichtmcov);
                   11797:   fclose(ficgp);
                   11798:   fclose(ficlog);
                   11799:   /*------ End -----------*/
1.227     brouard  11800:   
                   11801:   
                   11802:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  11803: #ifdef WIN32
1.227     brouard  11804:   if (_chdir(pathcd) != 0)
                   11805:     printf("Can't move to directory %s!\n",path);
                   11806:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  11807: #else
1.227     brouard  11808:     if(chdir(pathcd) != 0)
                   11809:       printf("Can't move to directory %s!\n", path);
                   11810:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  11811: #endif 
1.126     brouard  11812:     printf("Current directory %s!\n",pathcd);
                   11813:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   11814:   sprintf(plotcmd,"gnuplot");
1.157     brouard  11815: #ifdef _WIN32
1.126     brouard  11816:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   11817: #endif
                   11818:   if(!stat(plotcmd,&info)){
1.158     brouard  11819:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11820:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  11821:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  11822:     }else
                   11823:       strcpy(pplotcmd,plotcmd);
1.157     brouard  11824: #ifdef __unix
1.126     brouard  11825:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   11826:     if(!stat(plotcmd,&info)){
1.158     brouard  11827:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11828:     }else
                   11829:       strcpy(pplotcmd,plotcmd);
                   11830: #endif
                   11831:   }else
                   11832:     strcpy(pplotcmd,plotcmd);
                   11833:   
                   11834:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  11835:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  11836:   
1.126     brouard  11837:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  11838:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  11839:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  11840:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  11841:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  11842:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  11843:   }
1.158     brouard  11844:   printf(" Successful, please wait...");
1.126     brouard  11845:   while (z[0] != 'q') {
                   11846:     /* chdir(path); */
1.154     brouard  11847:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  11848:     scanf("%s",z);
                   11849: /*     if (z[0] == 'c') system("./imach"); */
                   11850:     if (z[0] == 'e') {
1.158     brouard  11851: #ifdef __APPLE__
1.152     brouard  11852:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  11853: #elif __linux
                   11854:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  11855: #else
1.152     brouard  11856:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  11857: #endif
                   11858:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   11859:       system(pplotcmd);
1.126     brouard  11860:     }
                   11861:     else if (z[0] == 'g') system(plotcmd);
                   11862:     else if (z[0] == 'q') exit(0);
                   11863:   }
1.227     brouard  11864: end:
1.126     brouard  11865:   while (z[0] != 'q') {
1.195     brouard  11866:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  11867:     scanf("%s",z);
                   11868:   }
                   11869: }

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